pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/524-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 7,464E-05 0,17957286 ! positive regulation of muscle cell differentiation GO:0051149 13 5 1,000 7,464E-05 0,08978643 ! positive regulation of glycolysis GO:0045821 14 5 1,000 7,464E-05 0,05985762 ! microvillus organization GO:0032528 7 5 1,000 7,464E-05 0,04489322 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 9 5 1,000 7,464E-05 0,03591457 ! positive regulation of chemokine production GO:0032722 8 5 1,000 7,464E-05 0,02992881 ! regulation of hair follicle development GO:0051797 10 5 1,000 7,464E-05 0,02565327 GO:0042634|regulation of hair cycle, ! collagen metabolic process GO:0032963 45 31 2,000 8,58E-05 0,02580495 ! BMP signaling pathway GO:0030509 64 32 2,000 9,449E-05 0,02526032 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 1,118E-04 0,02688766 ! embryonic hemopoiesis GO:0035162 14 6 1,000 1,118E-04 0,02444333 ! cGMP-mediated signaling GO:0019934 13 6 1,000 1,118E-04 0,02240638 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 1,118E-04 0,02068281 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 1,118E-04 0,01920547 ! interaction with symbiont GO:0051702 13 6 1,000 1,118E-04 0,01792511 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 1,135E-04 0,01707436 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 2,000 1,135E-04 0,01606999 ! regulation of muscle development GO:0048634 70 35 2,000 1,239E-04 0,01656711 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,562E-04 0,01977646 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,562E-04 0,01878764 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,562E-04 0,01789299 ! oxygen homeostasis GO:0032364 12 7 1,000 1,562E-04 0,01707967 ! regulation of myoblast differentiation GO:0045661 16 7 1,000 1,562E-04 0,01633708 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 1,852E-04 0,01857122 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 2,079E-04 0,02000425 ! hemoglobin metabolic process GO:0020027 13 8 1,000 2,079E-04 0,01923486 ! ER overload response GO:0006983 12 8 1,000 2,079E-04 0,01852245 ! positive regulation of epidermis development GO:0045684 13 8 1,000 2,079E-04 0,01786094 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,079E-04 0,01724504 ! JAK-STAT cascade GO:0007259 71 44 2,000 2,464E-04 0,01975797 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,668E-04 0,02070459 ! regulation of glycolysis GO:0006110 21 9 1,000 2,668E-04 0,02005757 ! keratinocyte proliferation GO:0043616 14 9 1,000 2,668E-04 0,01944976 ! Rac protein signal transduction GO:0016601 17 9 1,000 2,668E-04 0,01887771 ! gas homeostasis GO:0033483 16 9 1,000 2,668E-04 0,01833835 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 2,668E-04 0,01782895 ! mitochondrion localization GO:0051646 15 9 1,000 2,668E-04 0,01734709 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 3,329E-04 0,02107542 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 3,329E-04 0,02053503 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 3,329E-04 0,02002165 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 3,329E-04 0,01953332 ! midbrain development GO:0030901 13 10 1,000 3,329E-04 0,01906824 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 3,329E-04 0,01862479 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 3,329E-04 0,0182015 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 3,329E-04 0,01779702 ! negative regulation of muscle development GO:0048635 20 11 1,000 4,061E-04 0,02124096 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,061E-04 0,02078902 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 4,061E-04 0,02035592 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 4,061E-04 0,01994049 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 4,061E-04 0,01954168 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 4,865E-04 0,02294906 ! histone acetylation GO:0016573 26 12 1,000 4,865E-04 0,02250773 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 4,865E-04 0,02208306 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,865E-04 0,02167411 ! regulation of chemokine production GO:0032642 18 13 1,000 5,739E-04 0,02510413 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 5,739E-04 0,02465584 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 5,739E-04 0,02422328 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 5,739E-04 0,02380564 ! chromatin silencing GO:0006342 26 13 1,000 5,739E-04 0,02340216 ! regulation of epidermis development GO:0045682 19 13 1,000 5,739E-04 0,02301212 ! embryonic placenta development GO:0001892 23 13 1,000 5,739E-04 0,02263487 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 6,683E-04 0,02593494 ! hair follicle morphogenesis GO:0031069 26 14 1,000 6,683E-04 0,02552327 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 6,683E-04 0,02512447 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 6,683E-04 0,02473794 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 7,698E-04 0,02806101 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 7,698E-04 0,02764219 ! muscle maintenance GO:0046716 26 15 1,000 7,698E-04 0,02723569 ! cell killing GO:0001906 29 15 1,000 7,698E-04 0,02684097 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 7,698E-04 0,02645753 ! lung development GO:0030324 144 67 2,000 8,514E-04 0,02885079 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 8,781E-04 0,02934468 ! respiratory tube development GO:0030323 150 70 2,000 9,671E-04 0,03187404 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 9,935E-04 0,03230059 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 9,935E-04 0,03186992 ! heart looping GO:0001947 30 17 1,000 9,935E-04 0,03145058 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 9,935E-04 0,03104213 ! neural crest cell migration GO:0001755 37 17 1,000 9,935E-04 0,03064415 ! respiratory system development GO:0060541 153 72 2,000 1,049E-03 0,03196289 ! epidermis morphogenesis GO:0048730 40 18 1,000 1,116E-03 0,03355271 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,116E-03 0,03313848 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 1,116E-03 0,03273435 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 1,116E-03 0,03233996 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,116E-03 0,03195497 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 1,245E-03 0,03523112 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,245E-03 0,03482146 ! peptide cross-linking GO:0018149 37 19 1,000 1,245E-03 0,03442121 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 1,245E-03 0,03403006 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 1,372E-03 0,03710149 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,38E-03 0,03690486 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,38E-03 0,03649931 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,38E-03 0,03610258 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 1,38E-03 0,03571438 ! peptidyl-serine modification GO:0018209 43 20 1,000 1,38E-03 0,03533444 ! response to hypoxia GO:0001666 171 81 2,000 1,475E-03 0,03735335 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 1,523E-03 0,03817191 ! collagen catabolic process GO:0030574 28 21 1,000 1,523E-03 0,03777839 ! response to oxygen levels GO:0070482 176 83 2,000 1,582E-03 0,03884047 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,672E-03 0,04064397 ! activation of JUN kinase activity GO:0007257 42 22 1,000 1,672E-03 0,04023753 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,991E-03 0,04743016 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,991E-03 0,04696516 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,991E-03 0,04650919 ! response to starvation GO:0042594 42 25 1,000 2,16E-03 0,049978 ! osteoblast differentiation GO:0001649 60 25 1,000 2,16E-03 0,04950201 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,16E-03 0,04903501 ! neural crest cell development GO:0014032 54 25 1,000 2,16E-03 0,04857674 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 2,16E-03 0,04812696 ! somitogenesis GO:0001756 43 25 1,000 2,16E-03 0,04768543 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,16E-03 0,04725192 ! embryonic pattern specification GO:0009880 44 26 1,000 2,336E-03 0,05063787 ! molting cycle process GO:0022404 50 26 1,000 2,336E-03 0,05018575 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 2,336E-03 0,04974163 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 2,336E-03 0,0493053 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,336E-03 0,04887656 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 2,336E-03 0,04845521 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 2,336E-03 0,04804106 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 2,336E-03 0,04763393 ! protein amino acid acylation GO:0043543 55 27 1,000 2,519E-03 0,05092131 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 2,519E-03 0,05049696 ! response to virus GO:0009615 160 98 2,000 2,542E-03 0,05055325 ! negative regulation of protein modification process GO:0031400 60 28 1,000 2,707E-03 0,05339442 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,707E-03 0,05296031 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 2,707E-03 0,05253322 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 2,903E-03 0,05587333 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 2,903E-03 0,05542989 ! acute-phase response GO:0006953 49 30 1,000 3,105E-03 0,05881645 ! iron ion homeostasis GO:0055072 54 31 1,000 3,313E-03 0,06227034 ! mesoderm formation GO:0001707 69 31 1,000 3,313E-03 0,06178762 ! hindbrain development GO:0030902 61 32 1,000 3,527E-03 0,06528324 ! positive regulation of catabolic process GO:0009896 64 32 1,000 3,527E-03 0,06478489 ! gene silencing GO:0016458 65 32 1,000 3,527E-03 0,0642941 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 3,748E-03 0,06780643 ! ceramide metabolic process GO:0006672 64 33 1,000 3,748E-03 0,06730041 ! formation of primary germ layer GO:0001704 72 33 1,000 3,748E-03 0,06680189 ! mesoderm morphogenesis GO:0048332 76 34 1,000 3,975E-03 0,07032957 ! placenta development GO:0001890 53 34 1,000 3,975E-03 0,06981622 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 3,975E-03 0,0693103 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 4,209E-03 0,07285205 ! negative regulation of secretion GO:0051048 63 35 1,000 4,209E-03 0,07233168 ! odontogenesis GO:0042476 66 35 1,000 4,209E-03 0,07181869 ! female gonad development GO:0008585 58 35 1,000 4,209E-03 0,07131292 ! sphingoid metabolic process GO:0046519 70 36 1,000 4,448E-03 0,07484622 ! embryonic organ development GO:0048568 57 36 1,000 4,448E-03 0,07432645 ! tissue remodeling GO:0048771 76 37 1,000 4,694E-03 0,07789283 ! glycogen metabolic process GO:0005977 61 37 1,000 4,694E-03 0,07735932 ! carbohydrate homeostasis GO:0033500 53 38 1,000 4,946E-03 0,08095717 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 4,946E-03 0,08041016 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 62 38 1,000 4,946E-03 0,07987049 GO:0006073|cellular glucan metabolic process, ! segmentation GO:0035282 67 39 1,000 5,204E-03 0,0834777 ! Rho protein signal transduction GO:0007266 74 39 1,000 5,204E-03 0,08292487 ! regulation of hormone secretion GO:0046883 62 40 1,000 5,469E-03 0,08656073 ! mesenchymal cell development GO:0014031 87 40 1,000 5,469E-03 0,08599497 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 6,015E-03 0,09397353 GO:0090047|positive regulation of transcription regulator activity, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 6,015E-03 0,09336725 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 6,015E-03 0,09276874 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 6,297E-03 0,09650239 ! energy reserve metabolic process GO:0006112 74 43 1,000 6,297E-03 0,09589162 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 6,297E-03 0,09528852 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 6,585E-03 0,09902575 ! B cell differentiation GO:0030183 107 44 1,000 6,585E-03 0,09841068 ! maintenance of location in cell GO:0051651 97 44 1,000 6,585E-03 0,09780321 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 7,179E-03 0,10597032 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 7,179E-03 0,10532415 ! negative regulation of cell migration GO:0030336 115 46 1,000 7,179E-03 0,10468583 ! positive regulation of protein transport GO:0051222 72 46 1,000 7,179E-03 0,10405519 ! positive regulation of DNA binding GO:0043388 73 47 1,000 7,485E-03 0,1078371 ! JNK cascade GO:0007254 91 47 1,000 7,485E-03 0,10719521 ! regulation of JNK cascade GO:0046328 94 47 1,000 7,485E-03 0,10656092 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 7,797E-03 0,11034351 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 8,114E-03 0,11416307 ! regulation of ossification GO:0030278 117 50 1,000 8,437E-03 0,11801848 ! histone modification GO:0016570 91 50 1,000 8,437E-03 0,1173363 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 8,437E-03 0,11666195 ! positive regulation of cytokine production GO:0001819 86 50 1,000 8,437E-03 0,11599531 ! positive regulation of binding GO:0051099 78 51 1,000 8,766E-03 0,11983068 ! chromatin remodeling GO:0006338 109 51 1,000 8,766E-03 0,11915367 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 8,766E-03 0,11848427 ! regulation of cell shape GO:0008360 125 51 1,000 8,766E-03 0,11782235 ! regulation of angiogenesis GO:0045765 114 52 1,000 9,1E-03 0,12163815 ! covalent chromatin modification GO:0016569 101 52 1,000 9,1E-03 0,12096612 ! cartilage development GO:0051216 90 52 1,000 9,1E-03 0,12030147 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01013714 0,13327846 ! gastrulation GO:0007369 112 55 1,000 0,01013714 0,13255412 ! heart morphogenesis GO:0003007 97 55 1,000 0,01013714 0,13183762 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,01013714 0,13112881 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01085625 0,1396799 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,01085625 0,13893692 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01085625 0,1382018 ! maintenance of location GO:0051235 118 57 1,000 0,01085625 0,13747442 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01122404 0,14138761 ! mesoderm development GO:0007498 119 61 1,000 0,01235993 0,15488538 ! sphingolipid metabolic process GO:0006665 107 61 1,000 0,01235993 0,15408286 ! gonad development GO:0008406 98 62 1,000 0,0127493 0,15811761 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0127493 0,15730675 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,01354396 0,166259 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01370476 0,1673789 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01370476 0,16653355 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01370476 0,1656967 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01370476 0,16486822 ! neuron fate determination GO:0048664 7 5 0,000 0,01370476 0,16404798 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01370476 0,16323586 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01370476 0,16243174 ! polyol transport GO:0015791 12 5 0,000 0,01370476 0,16163551 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01370476 0,16084704 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01370476 0,16006623 ! response to superoxide GO:0000303 10 5 0,000 0,01370476 0,15929296 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01370476 0,15852713 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01370476 0,15776863 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01370476 0,15701735 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01370476 0,15627319 ! female meiosis GO:0007143 7 5 0,000 0,01370476 0,15553605 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01370476 0,15480584 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01370476 0,15408245 ! cobalt ion transport GO:0006824 11 5 0,000 0,01370476 0,15336578 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01370476 0,15265576 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01370476 0,15195227 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01370476 0,15125524 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01370476 0,15056458 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01370476 0,1498802 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01370476 0,14920201 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01370476 0,14852993 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01370476 0,14786387 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01370476 0,14720377 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01370476 0,14654953 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01370476 0,14590108 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01370476 0,14525834 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01370476 0,14462124 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01370476 0,14398971 ! negative chemotaxis GO:0050919 14 5 0,000 0,01370476 0,14336367 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01370476 0,14274304 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01370476 0,14212777 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01370476 0,14151778 ! behavioral response to pain GO:0048266 9 5 0,000 0,01370476 0,14091301 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01370476 0,14031338 ! Notch receptor processing GO:0007220 8 5 0,000 0,01370476 0,13971883 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01370476 0,1391293 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01370476 0,13854472 ! micturition GO:0060073 9 5 0,000 0,01370476 0,13796504 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01370476 0,13739018 ! copulation GO:0007620 9 5 0,000 0,01370476 0,1368201 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01370476 0,13625472 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01370476 0,13569401 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01370476 0,13513788 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01370476 0,1345863 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01370476 0,1340392 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01370476 0,13349653 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01370476 0,13295824 ! grooming behavior GO:0007625 6 5 0,000 0,01370476 0,13242427 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01370476 0,13189457 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01370476 0,1313691 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01370476 0,13084779 ! response to protozoan GO:0001562 10 5 0,000 0,01370476 0,13033061 ! lymph vessel development GO:0001945 10 5 0,000 0,01370476 0,12981749 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01370476 0,12930841 ! endochondral ossification GO:0001958 16 5 0,000 0,01370476 0,12880329 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01370476 0,12830211 ! parathyroid gland development GO:0060017 13 5 0,000 0,01370476 0,12780482 ! anagen GO:0042640 6 5 0,000 0,01370476 0,12731136 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01370476 0,12682171 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01370476 0,1263358 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01370476 0,1258536 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01370476 0,12537507 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01370476 0,12490016 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01370476 0,12442884 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01370476 0,12396107 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01370476 0,12349679 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01370476 0,12303598 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01370476 0,1225786 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01370476 0,12212461 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01370476 0,12167396 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01370476 0,12122663 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01370476 0,12078258 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01370476 0,12034176 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01370476 0,11990416 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01370476 0,11946972 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01370476 0,11903842 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01370476 0,11861023 ! histidine catabolic process GO:0006548 6 5 0,000 0,01370476 0,1181851 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01370476 0,11776301 ! valine metabolic process GO:0006573 10 5 0,000 0,01370476 0,11734393 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01370476 0,11692781 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01370476 0,11651464 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01370476 0,11610438 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01370476 0,11569699 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01370476 0,11529246 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01370476 0,11489074 ! polyol catabolic process GO:0046174 7 5 0,000 0,01370476 0,11449182 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01370476 0,11409565 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01370476 0,11370222 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01370476 0,11331149 ! muscle cell migration GO:0014812 8 5 0,000 0,01370476 0,11292344 ! mitochondrial fission GO:0000266 8 5 0,000 0,01370476 0,11253803 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01370476 0,11215525 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01370476 0,11177506 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01370476 0,11139744 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01370476 0,11102237 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01370476 0,11064981 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01370476 0,11027974 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01370476 0,10991214 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01370476 0,10954699 ! response to food GO:0032094 6 5 0,000 0,01370476 0,10918425 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01370476 0,10882391 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01370476 0,10846593 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01370476 0,10811031 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01370476 0,107757 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01370476 0,107406 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01370476 0,10705728 ! forebrain neuron development GO:0021884 13 5 0,000 0,01370476 0,10671082 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01370476 0,10636659 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01370476 0,10602458 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01370476 0,10568475 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01370476 0,1053471 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01370476 0,1050116 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01370476 0,10467823 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01370476 0,10434697 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01370476 0,1040178 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01370476 0,1036907 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01370476 0,10336565 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01370476 0,10304264 ! basic amino acid transport GO:0015802 11 5 0,000 0,01370476 0,10272163 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01370476 0,10240262 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01370476 0,10208558 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01370476 0,1017705 ! depyrimidination GO:0045008 10 5 0,000 0,01370476 0,10145736 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01370476 0,10114615 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01370476 0,10083683 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01370476 0,1005294 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01370476 0,10022384 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01370476 0,09992013 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01370476 0,09961826 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01370476 0,0993182 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01370476 0,09901995 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01370476 0,09872348 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01370476 0,09842879 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01370476 0,09813584 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01370476 0,09784464 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01370476 0,09755516 ! response to arsenic GO:0046685 10 5 0,000 0,01370476 0,09726738 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01370476 0,0969813 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01370476 0,0966969 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01370476 0,09641416 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01370476 0,09613307 ! response to cadmium ion GO:0046686 7 5 0,000 0,01370476 0,09585361 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01370476 0,09557578 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01370476 0,09529955 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01370476 0,09502491 ! decidualization GO:0046697 11 5 0,000 0,01370476 0,09475185 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01370476 0,09448035 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01370476 0,09421041 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01370476 0,093942 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01370476 0,09367512 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01370476 0,09340975 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01370476 0,09314589 ! neural tube patterning GO:0021532 7 5 0,000 0,01370476 0,0928835 ! embryonic cleavage GO:0040016 6 5 0,000 0,01370476 0,09262259 ! peroxisome fission GO:0016559 5 5 0,000 0,01370476 0,09236315 ! histone demethylation GO:0016577 10 5 0,000 0,01370476 0,09210515 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01370476 0,09184859 ! mitotic recombination GO:0006312 9 5 0,000 0,01370476 0,09159345 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01370476 0,09133973 ! metaphase plate congression GO:0051310 7 5 0,000 0,01370476 0,09108741 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01370476 0,09083648 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01370476 0,09058693 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01370476 0,09033875 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01370476 0,09009192 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01370476 0,08984644 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01370476 0,08960229 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01370476 0,08935947 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01370476 0,08911796 ! plasminogen activation GO:0031639 5 5 0,000 0,01370476 0,08887774 ! B cell homeostasis GO:0001782 13 5 0,000 0,01370476 0,08863883 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01370476 0,08840119 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01370476 0,08816482 ! metaphase GO:0051323 8 5 0,000 0,01370476 0,08792972 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01370476 0,08769586 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01370476 0,08746325 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01370476 0,08723186 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01370476 0,0870017 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01370476 0,08677275 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01370476 0,086545 ! response to redox state GO:0051775 5 5 0,000 0,01370476 0,08631844 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01370476 0,08609306 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01370476 0,08586886 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01370476 0,08564583 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01370476 0,08542395 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01370476 0,08520321 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01370476 0,08498362 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01370476 0,08476515 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01370476 0,0845478 ! striatum development GO:0021756 9 5 0,000 0,01370476 0,08433157 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01370476 0,08411644 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01370476 0,0839024 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01370476 0,08368945 ! glial cell migration GO:0008347 11 5 0,000 0,01370476 0,08347758 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01370476 0,08326678 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01370476 0,08305704 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01370476 0,08284835 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01370476 0,08264071 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01370476 0,08243411 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01370476 0,08222854 ! neuroprotection GO:0043526 6 5 0,000 0,01370476 0,08202399 ! neural plate development GO:0001840 8 5 0,000 0,01370476 0,08182046 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01370476 0,08161793 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01370476 0,0814164 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01370476 0,08121587 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01370476 0,08101632 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01370476 0,08081775 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01370476 0,08062015 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01370476 0,08042352 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01370476 0,08022784 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01370476 0,08003312 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01370476 0,07983933 ! spindle assembly GO:0051225 6 5 0,000 0,01370476 0,07964648 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01370476 0,07945456 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01370476 0,07926357 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01370476 0,07907349 ! drug metabolic process GO:0017144 6 5 0,000 0,01370476 0,07888431 ! stem cell division GO:0017145 11 5 0,000 0,01370476 0,07869605 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01370476 0,07850867 ! organ regeneration GO:0031100 7 5 0,000 0,01370476 0,07832219 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01370476 0,0781366 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01370476 0,07795188 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01370476 0,07776803 ! extracellular matrix organization GO:0030198 133 66 1,000 0,01435963 0,0812924 ! cell projection assembly GO:0030031 120 66 1,000 0,01435963 0,08110158 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,01477527 0,08325363 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01477527 0,08305911 ! membrane lipid metabolic process GO:0006643 117 68 1,000 0,01519607 0,0852255 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01642336 0,09189441 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01642336 0,0916812 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01642336 0,09146897 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01642336 0,09125773 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01642336 0,09104746 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01642336 0,09083815 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01642336 0,09062981 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01642336 0,09042242 ! sleep GO:0030431 13 6 0,000 0,01642336 0,09021597 ! response to oxygen radical GO:0000305 11 6 0,000 0,01642336 0,09001047 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01642336 0,0898059 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01642336 0,08960226 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01642336 0,08939954 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01642336 0,08919774 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01642336 0,08899684 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01642336 0,08879685 ! forebrain regionalization GO:0021871 8 6 0,000 0,01642336 0,08859775 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01642336 0,08839955 ! male meiosis GO:0007140 7 6 0,000 0,01642336 0,08820222 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01642336 0,08800578 ! response to zinc ion GO:0010043 9 6 0,000 0,01642336 0,08781022 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01642336 0,08761551 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01642336 0,08742167 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01642336 0,08722869 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01642336 0,08703656 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01642336 0,08684527 ! malate metabolic process GO:0006108 11 6 0,000 0,01642336 0,08665482 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01642336 0,0864652 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01642336 0,08627641 ! protein refolding GO:0042026 15 6 0,000 0,01642336 0,08608845 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01642336 0,0859013 ! opsonization GO:0008228 8 6 0,000 0,01642336 0,08571496 ! mating behavior GO:0007617 7 6 0,000 0,01642336 0,08552943 ! neuron remodeling GO:0016322 15 6 0,000 0,01642336 0,0853447 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01642336 0,08516077 ! equilibrioception GO:0050957 14 6 0,000 0,01642336 0,08497763 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01642336 0,08479527 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01642336 0,0846137 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01642336 0,0844329 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01642336 0,08425287 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01642336 0,08407361 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01642336 0,08389511 ! toxin metabolic process GO:0009404 11 6 0,000 0,01642336 0,08371737 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01642336 0,08354037 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01642336 0,08336413 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01642336 0,08318862 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01642336 0,08301386 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01642336 0,08283983 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01642336 0,08266652 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01642336 0,08249394 ! thymic T cell selection GO:0045061 12 6 0,000 0,01642336 0,08232208 ! protein lipoylation GO:0009249 10 6 0,000 0,01642336 0,08215093 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01642336 0,08198049 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01642336 0,08181076 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01642336 0,08164173 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01642336 0,0814734 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01642336 0,08130575 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,01642336 0,0811388 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01642336 0,08097253 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01642336 0,08080695 ! hyperosmotic response GO:0006972 9 6 0,000 0,01642336 0,08064203 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01642336 0,08047779 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01642336 0,08031422 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01642336 0,08015131 ! urea metabolic process GO:0019627 7 6 0,000 0,01642336 0,07998906 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01642336 0,07982747 ! neutrophil activation GO:0042119 8 6 0,000 0,01642336 0,07966653 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01642336 0,07950623 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01642336 0,07934658 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01642336 0,07918757 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01642336 0,07902919 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01642336 0,07887145 ! neuron apoptosis GO:0051402 9 6 0,000 0,01642336 0,07871434 ! nucleoside salvage GO:0043174 9 6 0,000 0,01642336 0,07855785 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01642336 0,07840198 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01642336 0,07824673 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01642336 0,07809209 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01642336 0,07793806 ! carnitine transport GO:0015879 10 6 0,000 0,01642336 0,07778464 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01642336 0,07763182 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01642336 0,0774796 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01642336 0,07732798 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01642336 0,07717695 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01642336 0,0770265 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01642336 0,07687665 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01642336 0,07672737 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01642336 0,07657868 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01642336 0,07643055 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01642336 0,07628301 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01642336 0,07613602 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01642336 0,07598961 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01642336 0,07584376 ! neural nucleus development GO:0048857 14 6 0,000 0,01642336 0,07569846 ! response to UV-C GO:0010225 11 6 0,000 0,01642336 0,07555372 ! astrocyte development GO:0014002 15 6 0,000 0,01642336 0,07540954 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01642336 0,0752659 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01642336 0,07512281 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01642336 0,07498026 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01642336 0,07483825 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01642336 0,07469678 ! response to copper ion GO:0046688 10 6 0,000 0,01642336 0,07455584 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01642336 0,07441544 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01642336 0,07427556 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01642336 0,0741362 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01642336 0,07399737 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01642336 0,07385906 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01642336 0,07372126 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01642336 0,07358398 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01642336 0,07344721 ! hair follicle maturation GO:0048820 7 6 0,000 0,01642336 0,07331094 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01642336 0,07317518 ! Schwann cell development GO:0014044 15 6 0,000 0,01642336 0,07303992 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01642336 0,07290516 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01642336 0,0727709 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01642336 0,07263713 ! subpallium development GO:0021544 10 6 0,000 0,01642336 0,07250385 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01642336 0,07237106 ! histone ubiquitination GO:0016574 8 6 0,000 0,01642336 0,07223875 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01642336 0,07210693 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01642336 0,07197559 ! G2 phase GO:0051319 16 6 0,000 0,01642336 0,07184472 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01642336 0,07171433 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01642336 0,07158441 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01642336 0,07145497 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01642336 0,07132599 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01642336 0,07119747 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01642336 0,07106942 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01642336 0,07094183 ! receptor internalization GO:0031623 10 6 0,000 0,01642336 0,07081469 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01642336 0,07068801 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01642336 0,07056178 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01642336 0,070436 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01642336 0,07031067 ! protein deubiquitination GO:0016579 14 6 0,000 0,01642336 0,07018578 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01642336 0,07006134 ! protein destabilization GO:0031648 9 6 0,000 0,01642336 0,06993734 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01642336 0,06981378 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01642336 0,06969065 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01642336 0,06956795 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01642336 0,06944569 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01642336 0,06932385 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01642336 0,06920245 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01642336 0,06908146 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01642336 0,0689609 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01642336 0,06884076 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01642336 0,06872104 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01642336 0,06860173 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01642336 0,06848284 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01642336 0,06836435 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01642336 0,06824628 ! catecholamine transport GO:0051937 9 6 0,000 0,01642336 0,06812862 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01642336 0,06801135 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01642336 0,0678945 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01642336 0,06777804 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01642336 0,06766198 ! maternal placenta development GO:0001893 12 6 0,000 0,01642336 0,06754632 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01642336 0,06743105 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01642336 0,06731618 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01642336 0,0672017 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01642336 0,0670876 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01642336 0,06697389 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01642336 0,06686057 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01642336 0,06674763 ! reproductive structure development GO:0048608 113 71 1,000 0,01648912 0,06690189 ! B cell activation GO:0042113 160 71 1,000 0,01648912 0,06678926 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,01648912 0,06667701 ! acute inflammatory response GO:0002526 113 72 1,000 0,01693025 0,06834594 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01782751 0,07184754 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 1,000 0,01782751 0,07172739 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01828357 0,07343951 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,01874455 0,07516564 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01874455 0,07504057 ! tRNA transcription GO:0009304 14 7 0,000 0,01913455 0,07647465 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01913455 0,07634782 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01913455 0,07622142 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01913455 0,07609543 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01913455 0,07596986 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01913455 0,07584471 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01913455 0,07571996 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01913455 0,07559563 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01913455 0,0754717 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01913455 0,07534818 ! prostate gland development GO:0030850 13 7 0,000 0,01913455 0,07522506 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01913455 0,07510234 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01913455 0,07498003 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01913455 0,07485811 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01913455 0,07473659 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01913455 0,07461546 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01913455 0,07449472 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01913455 0,07437437 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01913455 0,07425442 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01913455 0,07413484 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01913455 0,07401566 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01913455 0,07389685 ! glycolipid transport GO:0046836 10 7 0,000 0,01913455 0,07377843 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01913455 0,07366038 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01913455 0,07354271 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01913455 0,07342542 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01913455 0,0733085 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01913455 0,07319195 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01913455 0,07307577 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01913455 0,07295996 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01913455 0,07284452 ! mRNA stabilization GO:0048255 18 7 0,000 0,01913455 0,07272944 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01913455 0,07261473 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01913455 0,07250037 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01913455 0,07238638 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01913455 0,07227274 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01913455 0,07215946 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01913455 0,07204654 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01913455 0,07193396 ! lipoprotein transport GO:0042953 14 7 0,000 0,01913455 0,07182174 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01913455 0,07170987 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01913455 0,07159835 ! rhythmic behavior GO:0007622 15 7 0,000 0,01913455 0,07148717 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01913455 0,07137634 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01913455 0,07126585 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01913455 0,0711557 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01913455 0,07104589 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01913455 0,07093642 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01913455 0,07082729 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01913455 0,07071849 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01913455 0,07061003 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01913455 0,07050189 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01913455 0,07039409 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01913455 0,07028662 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01913455 0,07017948 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01913455 0,07007266 ! spinal cord patterning GO:0021511 13 7 0,000 0,01913455 0,06996617 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01913455 0,06986 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01913455 0,06975415 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01913455 0,06964862 ! adrenal gland development GO:0030325 17 7 0,000 0,01913455 0,06954341 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01913455 0,06943852 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01913455 0,06933394 ! ovulation GO:0030728 9 7 0,000 0,01913455 0,06922968 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01913455 0,06912573 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01913455 0,0690221 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01913455 0,06891877 ! microtubule nucleation GO:0007020 20 7 0,000 0,01913455 0,06881575 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01913455 0,06871304 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01913455 0,06861064 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01913455 0,06850854 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01913455 0,06840674 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01913455 0,06830525 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01913455 0,06820406 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01913455 0,06810316 ! galactose metabolic process GO:0006012 13 7 0,000 0,01913455 0,06800257 ! vesicle fusion GO:0006906 17 7 0,000 0,01913455 0,06790227 ! response to dietary excess GO:0002021 8 7 0,000 0,01913455 0,06780226 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01913455 0,06770256 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01913455 0,06760314 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01913455 0,06750401 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01913455 0,06740518 ! organ growth GO:0035265 15 7 0,000 0,01913455 0,06730663 ! purine salvage GO:0043101 10 7 0,000 0,01913455 0,06720838 ! nucleoside transport GO:0015858 8 7 0,000 0,01913455 0,0671104 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01913455 0,06701272 ! parturition GO:0007567 14 7 0,000 0,01913455 0,06691532 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01913455 0,0668182 ! rRNA modification GO:0000154 14 7 0,000 0,01913455 0,06672136 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01913455 0,0666248 ! spindle checkpoint GO:0031577 15 7 0,000 0,01913455 0,06652852 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01913455 0,06643252 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01913455 0,0663368 ! macrophage differentiation GO:0030225 11 7 0,000 0,01913455 0,06624135 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01913455 0,06614617 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01913455 0,06605127 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01913455 0,06595664 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01913455 0,06586229 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01913455 0,0657682 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01913455 0,06567438 ! fibrinolysis GO:0042730 10 7 0,000 0,01913455 0,06558082 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01913455 0,06548754 ! eating behavior GO:0042755 7 7 0,000 0,01913455 0,06539451 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01913455 0,06530176 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01913455 0,06520926 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01913455 0,06511703 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01913455 0,06502505 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01913455 0,06493334 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01913455 0,06484188 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01913455 0,06475069 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01913455 0,06465974 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01913455 0,06456906 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01913455 0,06447862 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01913455 0,06438844 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01913455 0,06429852 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01913455 0,06420884 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01913455 0,06411941 ! regulation of meiosis GO:0040020 12 7 0,000 0,01913455 0,06403023 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01913455 0,0639413 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01913455 0,06385262 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01913455 0,06376418 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01913455 0,06367599 ! transcription termination GO:0006353 13 7 0,000 0,01913455 0,06358804 ! response to tumor cell GO:0002347 13 7 0,000 0,01913455 0,06350033 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01913455 0,06341286 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01913455 0,06332564 ! anaphase GO:0051322 17 7 0,000 0,01913455 0,06323865 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01913455 0,0631519 ! axonal fasciculation GO:0007413 18 7 0,000 0,01913455 0,06306539 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01913455 0,06297912 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01913455 0,06289308 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01913455 0,06280728 ! diuresis GO:0030146 12 7 0,000 0,01913455 0,06272171 GO:0030147|natriuresis, ! thiamin metabolic process GO:0006772 7 7 0,000 0,01913455 0,06263638 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01913455 0,06255127 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01913455 0,0624664 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01913455 0,06238176 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01913455 0,06229734 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01913455 0,06221316 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01913455 0,0621292 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01913455 0,06204547 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01913455 0,06196196 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01913455 0,06187868 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01913455 0,06179562 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01913455 0,06171278 ! lymph node development GO:0048535 10 7 0,000 0,01913455 0,06163017 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01913455 0,06154778 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01913455 0,0614656 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01913455 0,06138365 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01913455 0,06130191 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01913455 0,0612204 ! adult feeding behavior GO:0008343 9 7 0,000 0,01913455 0,06113909 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01913455 0,06105801 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01913455 0,06097714 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01913455 0,06089648 ! muscle adaptation GO:0043500 14 7 0,000 0,01913455 0,06081603 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01913455 0,0607358 ! retina homeostasis GO:0001895 12 7 0,000 0,01913455 0,06065578 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01913455 0,06057597 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01913455 0,06049637 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01913455 0,06041698 ! protein prenylation GO:0018342 18 7 0,000 0,01913455 0,06033779 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01913455 0,06025882 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01913455 0,06018005 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01913455 0,06010148 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02183837 0,06850471 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02183837 0,06841551 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,02183837 0,06832655 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02183837 0,06823781 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02183837 0,0681493 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02183837 0,06806103 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02183837 0,06797298 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02183837 0,06788516 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02183837 0,06779757 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02183837 0,0677102 ! meiotic prophase I GO:0007128 13 8 0,000 0,02183837 0,06762305 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02183837 0,06753614 ! oligopeptide transport GO:0006857 15 8 0,000 0,02183837 0,06744944 ! UTP metabolic process GO:0046051 8 8 0,000 0,02183837 0,06736297 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02183837 0,06727671 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02183837 0,06719068 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02183837 0,06710487 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02183837 0,06701928 ! succinate metabolic process GO:0006105 14 8 0,000 0,02183837 0,0669339 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02183837 0,06684874 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02183837 0,0667638 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02183837 0,06667908 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02183837 0,06659457 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02183837 0,06651027 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02183837 0,06642619 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02183837 0,06634231 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02183837 0,06625865 ! reflex GO:0060004 16 8 0,000 0,02183837 0,06617521 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02183837 0,06609197 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02183837 0,06600894 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02183837 0,06592611 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02183837 0,0658435 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02183837 0,06576109 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02183837 0,06567889 ! pigment granule organization GO:0048753 16 8 0,000 0,02183837 0,0655969 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02183837 0,0655151 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02183837 0,06543352 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02183837 0,06535213 ! histidine metabolic process GO:0006547 16 8 0,000 0,02183837 0,06527095 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02183837 0,06518997 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02183837 0,06510919 ! glycine catabolic process GO:0006546 13 8 0,000 0,02183837 0,06502861 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02183837 0,06494822 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02183837 0,06486804 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02183837 0,06478806 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02183837 0,06470827 ! melanin metabolic process GO:0006582 15 8 0,000 0,02183837 0,06462868 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02183837 0,06454928 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02183837 0,06447008 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02183837 0,06439107 ! macrophage activation GO:0042116 12 8 0,000 0,02183837 0,06431226 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02183837 0,06423363 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02183837 0,06415521 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02183837 0,06407697 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02183837 0,06399892 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02183837 0,06392106 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02183837 0,06384339 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02183837 0,06376591 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02183837 0,06368862 ! osteoblast development GO:0002076 16 8 0,000 0,02183837 0,06361152 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02183837 0,0635346 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02183837 0,06345787 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02183837 0,06338132 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02183837 0,06330496 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02183837 0,06322878 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02183837 0,06315278 ! response to UV-B GO:0010224 16 8 0,000 0,02183837 0,06307697 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02183837 0,06300133 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02183837 0,06292588 ! intermediate filament organization GO:0045109 12 8 0,000 0,02183837 0,06285061 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02183837 0,06277552 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02183837 0,06270061 ! cellular extravasation GO:0045123 12 8 0,000 0,02183837 0,06262588 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02183837 0,06255133 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02183837 0,06247695 ! response to antibiotic GO:0046677 11 8 0,000 0,02183837 0,06240275 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02183837 0,06232872 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02183837 0,06225487 ! DNA topological change GO:0006265 12 8 0,000 0,02183837 0,0621812 ! response to tropane GO:0014073 15 8 0,000 0,02183837 0,0621077 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02183837 0,06203437 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02183837 0,06196122 ! melanosome transport GO:0032402 13 8 0,000 0,02183837 0,06188824 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,02183837 0,06181543 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02183837 0,06174279 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02183837 0,06167032 ! mast cell activation GO:0045576 14 8 0,000 0,02183837 0,06159802 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02183837 0,06152589 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02183837 0,06145393 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02183837 0,06138214 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02183837 0,06131052 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02183837 0,06123906 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02183837 0,06116777 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02183837 0,06109664 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02183837 0,06102568 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02183837 0,06095489 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02183837 0,06088426 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02183837 0,06081379 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02183837 0,06074348 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02183837 0,06067334 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02183837 0,06060336 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02183837 0,06053354 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02183837 0,06046388 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02183837 0,06039438 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02183837 0,06032504 ! hormone catabolic process GO:0042447 17 8 0,000 0,02183837 0,06025586 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02183837 0,06018684 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02183837 0,06011798 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02183837 0,06004927 ! ATP catabolic process GO:0006200 11 8 0,000 0,02183837 0,05998072 ! blastocyst growth GO:0001832 19 8 0,000 0,02183837 0,05991233 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02183837 0,05984409 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02183837 0,05977601 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02183837 0,05970808 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02183837 0,05964031 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02183837 0,05957269 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02183837 0,05950522 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02183837 0,05943791 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02183837 0,05937075 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02183837 0,05930374 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02183837 0,05923688 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02183837 0,05917017 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02183837 0,05910361 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02183837 0,05903721 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02183837 0,05897095 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02183837 0,05890484 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02183837 0,05883887 ! negative regulation of transport GO:0051051 153 84 1,000 0,02260583 0,06083851 ! negative regulation of growth GO:0045926 155 84 1,000 0,02260583 0,06077054 ! regulation of protein transport GO:0051223 154 87 1,000 0,02413138 0,06479921 GO:0070201|regulation of establishment of protein localization, ! regulation of developmental growth GO:0048638 15 9 0,000 0,02453482 0,06580911 ! axon extension GO:0048675 15 9 0,000 0,02453482 0,06573583 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02453482 0,06566271 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02453482 0,06558975 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02453482 0,06551695 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02453482 0,06544432 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02453482 0,06537184 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02453482 0,06529953 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02453482 0,06522737 ! phosphate transport GO:0006817 19 9 0,000 0,02453482 0,06515538 ! reproductive behavior GO:0019098 19 9 0,000 0,02453482 0,06508354 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02453482 0,06501186 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02453482 0,06494034 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02453482 0,06486898 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02453482 0,06479777 ! GTP metabolic process GO:0046039 9 9 0,000 0,02453482 0,06472672 ! RNA methylation GO:0001510 15 9 0,000 0,02453482 0,06465583 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02453482 0,06458509 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02453482 0,06451451 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02453482 0,06444407 ! artery development GO:0060840 24 9 0,000 0,02453482 0,0643738 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02453482 0,06430367 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02453482 0,0642337 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02453482 0,06416388 ! chemosensory behavior GO:0007635 20 9 0,000 0,02453482 0,06409422 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02453482 0,0640247 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02453482 0,06395533 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02453482 0,06388612 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02453482 0,06381705 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02453482 0,06374813 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02453482 0,06367937 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02453482 0,06361075 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02453482 0,06354227 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02453482 0,06347395 ! protein targeting to ER GO:0045047 22 9 0,000 0,02453482 0,06340577 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02453482 0,06333774 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02453482 0,06326985 ! T cell selection GO:0045058 23 9 0,000 0,02453482 0,06320211 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02453482 0,06313452 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02453482 0,06306706 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02453482 0,06299976 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02453482 0,06293259 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02453482 0,06286557 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02453482 0,06279869 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02453482 0,06273196 ! mannose metabolic process GO:0006013 13 9 0,000 0,02453482 0,06266536 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02453482 0,06259891 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02453482 0,0625326 ! receptor clustering GO:0043113 18 9 0,000 0,02453482 0,06246643 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02453482 0,06240039 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02453482 0,0623345 ! ruffle organization GO:0031529 15 9 0,000 0,02453482 0,06226875 ! retinol metabolic process GO:0042572 18 9 0,000 0,02453482 0,06220313 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02453482 0,06213765 ! behavioral fear response GO:0001662 22 9 0,000 0,02453482 0,06207232 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02453482 0,06200711 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02453482 0,06194205 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02453482 0,06187712 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02453482 0,06181233 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02453482 0,06174767 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02453482 0,06168315 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02453482 0,06161876 ! segment specification GO:0007379 13 9 0,000 0,02453482 0,06155451 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02453482 0,06149039 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02453482 0,0614264 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02453482 0,06136255 ! response to amine stimulus GO:0014075 13 9 0,000 0,02453482 0,06129883 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02453482 0,06123524 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02453482 0,06117178 ! erythrocyte development GO:0048821 15 9 0,000 0,02453482 0,06110846 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02453482 0,06104527 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02453482 0,0609822 ! renal water homeostasis GO:0003091 14 9 0,000 0,02453482 0,06091927 ! postreplication repair GO:0006301 22 9 0,000 0,02453482 0,06085647 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02453482 0,06079379 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02453482 0,06073125 ! icosanoid secretion GO:0032309 15 9 0,000 0,02453482 0,06066883 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02453482 0,06060654 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02453482 0,06054438 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02453482 0,06048235 ! regulation of cell division GO:0051302 15 9 0,000 0,02453482 0,06042044 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02453482 0,06035866 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02453482 0,06029701 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02453482 0,06023548 ! sterol catabolic process GO:0016127 11 9 0,000 0,02453482 0,06017408 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02453482 0,0601128 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02453482 0,06005165 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02453482 0,05999062 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02453482 0,05992972 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02453482 0,05986894 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02453482 0,05980828 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02453482 0,05974775 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02453482 0,05968733 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02453482 0,05962704 ! purine base metabolic process GO:0006144 21 9 0,000 0,02453482 0,05956687 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02453482 0,05950683 ! pigment granule transport GO:0051904 17 9 0,000 0,02453482 0,0594469 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02453482 0,05938709 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02453482 0,05932741 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02453482 0,05926784 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02453482 0,0592084 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02453482 0,05914907 ! regulation of DNA binding GO:0051101 155 88 1,000 0,02464906 0,05936501 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02517129 0,06056212 ! ossification GO:0001503 188 90 1,000 0,02569802 0,06176767 ! sex differentiation GO:0007548 145 90 1,000 0,02569802 0,06170602 ! bone development GO:0060348 189 91 1,000 0,02622923 0,06291878 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02722392 0,0652398 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02722392 0,06517489 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02722392 0,0651101 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02722392 0,06504544 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02722392 0,06498091 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02722392 0,06491651 ! synapsis GO:0007129 13 10 0,000 0,02722392 0,06485224 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02722392 0,06478809 ! N-glycan processing GO:0006491 20 10 0,000 0,02722392 0,06472407 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02722392 0,06466018 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02722392 0,06459641 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02722392 0,06453277 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02722392 0,06446925 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02722392 0,06440586 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02722392 0,0643426 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02722392 0,06427945 ! androgen metabolic process GO:0008209 17 10 0,000 0,02722392 0,06421643 ! phospholipid efflux GO:0033700 16 10 0,000 0,02722392 0,06415354 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02722392 0,06409076 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02722392 0,06402812 ! lung alveolus development GO:0048286 26 10 0,000 0,02722392 0,06396559 ! pathogenesis GO:0009405 13 10 0,000 0,02722392 0,06390318 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02722392 0,0638409 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02722392 0,06377874 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02722392 0,06371669 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02722392 0,06365477 ! endoderm development GO:0007492 16 10 0,000 0,02722392 0,06359297 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02722392 0,06353129 ! arginine catabolic process GO:0006527 13 10 0,000 0,02722392 0,06346973 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02722392 0,06340829 ! proline metabolic process GO:0006560 13 10 0,000 0,02722392 0,06334696 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02722392 0,06328576 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02722392 0,06322467 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02722392 0,0631637 ! V(D)J recombination GO:0033151 28 10 0,000 0,02722392 0,06310285 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02722392 0,06304212 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02722392 0,0629815 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02722392 0,062921 ! B cell proliferation GO:0042100 18 10 0,000 0,02722392 0,06286062 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02722392 0,06280035 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02722392 0,06274019 ! multicellular organism growth GO:0035264 18 10 0,000 0,02722392 0,06268015 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02722392 0,06262023 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02722392 0,06256042 ! epithelial cell development GO:0002064 20 10 0,000 0,02722392 0,06250073 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02722392 0,06244115 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02722392 0,06238168 ! macroautophagy GO:0016236 17 10 0,000 0,02722392 0,06232232 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02722392 0,06226308 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02722392 0,06220395 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02722392 0,06214494 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02722392 0,06208603 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02722392 0,06202724 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02722392 0,06196855 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02722392 0,06190998 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02722392 0,06185152 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02722392 0,06179317 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02722392 0,06173493 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02722392 0,0616768 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02722392 0,06161878 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02722392 0,06156087 ! response to dsRNA GO:0043331 20 10 0,000 0,02722392 0,06150306 ! DNA ligation GO:0006266 19 10 0,000 0,02722392 0,06144537 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02722392 0,06138778 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02722392 0,0613303 ! melanosome localization GO:0032400 16 10 0,000 0,02722392 0,06127293 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02722392 0,06121567 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02722392 0,06115851 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02722392 0,06110146 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02722392 0,06104451 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02722392 0,06098767 ! mRNA cleavage GO:0006379 17 10 0,000 0,02722392 0,06093094 ! protein sumoylation GO:0016925 15 10 0,000 0,02722392 0,06087431 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02722392 0,06081779 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02722392 0,06076137 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02722392 0,06070506 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02722392 0,06064885 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02722392 0,06059275 ! salivary gland development GO:0007431 27 10 0,000 0,02722392 0,06053675 ! prophase GO:0051324 15 10 0,000 0,02722392 0,06048085 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02722392 0,06042506 ! apical protein localization GO:0045176 15 10 0,000 0,02722392 0,06036937 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02722392 0,06031378 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02722392 0,06025829 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02722392 0,06020291 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02722392 0,06014762 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02722392 0,06009244 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02722392 0,06003736 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02722392 0,05998238 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02722392 0,0599275 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02722392 0,05987273 ! detection of calcium ion GO:0005513 23 10 0,000 0,02722392 0,05981805 ! oocyte development GO:0048599 17 10 0,000 0,02722392 0,05976347 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02722392 0,05970899 ! blastocyst formation GO:0001825 17 10 0,000 0,02722392 0,05965461 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02722392 0,05960033 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02722392 0,05954615 ! activation of innate immune response GO:0002218 12 10 0,000 0,02722392 0,05949206 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02722392 0,05943808 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02722392 0,05938419 ! response to nicotine GO:0035094 20 10 0,000 0,02722392 0,0593304 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02722392 0,05927671 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02722392 0,05922311 ! localization within membrane GO:0051668 20 10 0,000 0,02722392 0,05916961 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,027305 0,05929226 ! leukocyte differentiation GO:0002521 202 96 1,000 0,02895155 0,06281104 ! regulation of protein localization GO:0032880 176 97 1,000 0,02950907 0,06396291 ! respiratory burst GO:0045730 17 11 0,000 0,02990571 0,06476429 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02990571 0,06470605 ! neuron fate specification GO:0048665 17 11 0,000 0,02990571 0,06464792 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02990571 0,06458988 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02990571 0,06453195 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02990571 0,06447413 ! thyroid gland development GO:0030878 26 11 0,000 0,02990571 0,06441641 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02990571 0,06435879 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02990571 0,06430128 ! response to pain GO:0048265 24 11 0,000 0,02990571 0,06424387 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02990571 0,06418656 ! T cell proliferation GO:0042098 26 11 0,000 0,02990571 0,06412935 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02990571 0,06407224 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02990571 0,06401524 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02990571 0,06395834 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02990571 0,06390154 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02990571 0,06384484 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02990571 0,06378824 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02990571 0,06373174 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02990571 0,06367534 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02990571 0,06361904 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02990571 0,06356284 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02990571 0,06350673 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02990571 0,06345073 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02990571 0,06339483 ! lipid digestion GO:0044241 18 11 0,000 0,02990571 0,06333902 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02990571 0,06328332 ! UV protection GO:0009650 19 11 0,000 0,02990571 0,06322771 ! adult heart development GO:0007512 14 11 0,000 0,02990571 0,06317219 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02990571 0,06311678 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02990571 0,06306146 ! temperature homeostasis GO:0001659 17 11 0,000 0,02990571 0,06300624 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02990571 0,06295112 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02990571 0,06289609 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02990571 0,06284116 ! regulation of organ growth GO:0046620 13 11 0,000 0,02990571 0,06278633 ! pigment granule localization GO:0051875 20 11 0,000 0,02990571 0,06273159 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02990571 0,06267694 ! vasoconstriction GO:0042310 18 11 0,000 0,02990571 0,06262239 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02990571 0,06256794 ! embryonic axis specification GO:0000578 18 11 0,000 0,02990571 0,06251358 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02990571 0,06245931 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02990571 0,06240514 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02990571 0,06235107 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02990571 0,06229708 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02990571 0,06224319 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02990571 0,06218939 ! zymogen activation GO:0031638 15 11 0,000 0,02990571 0,06213569 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02990571 0,06208208 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02990571 0,06202856 ! nucleosome positioning GO:0016584 15 11 0,000 0,02990571 0,06197513 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02990571 0,0619218 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02990571 0,06186856 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02990571 0,0618154 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02990571 0,06176234 ! acid secretion GO:0046717 18 11 0,000 0,02990571 0,06170937 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02990571 0,06165649 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02990571 0,06160371 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02990571 0,06155101 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02990571 0,0614984 ! oocyte differentiation GO:0009994 18 11 0,000 0,02990571 0,06144588 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02990571 0,06139346 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02990571 0,06134112 ! cholesterol efflux GO:0033344 19 11 0,000 0,02990571 0,06128887 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02990571 0,06123671 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02990571 0,06118463 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02990571 0,06113265 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02990571 0,06108076 ! embryonic gut development GO:0048566 15 11 0,000 0,02990571 0,06102895 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02990571 0,06097723 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02990571 0,0609256 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02990571 0,06087405 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02990571 0,06082259 ! defense response to fungus GO:0050832 13 11 0,000 0,02990571 0,06077122 ! developmental induction GO:0031128 19 11 0,000 0,02990571 0,06071994 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02990571 0,06066874 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02990571 0,06061763 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02990571 0,06056661 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02990571 0,06051567 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02990571 0,06046481 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02990571 0,06041405 ! nucleus localization GO:0051647 19 11 0,000 0,02990571 0,06036336 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02990571 0,06031277 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,03063695 0,06173576 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03063695 0,06168409 GO:0060538|skeletal muscle organ development, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03258018 0,06554174 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03258018 0,06548699 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03258018 0,06543232 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03258018 0,06537775 ! virus-host interaction GO:0019048 29 12 0,000 0,03258018 0,06532327 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03258018 0,06526888 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03258018 0,06521458 ! cartilage condensation GO:0001502 20 12 0,000 0,03258018 0,06516037 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03258018 0,06510625 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03258018 0,06505222 ! protein complex disassembly GO:0043241 27 12 0,000 0,03258018 0,06499828 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03258018 0,06494443 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03258018 0,06489066 ! hippocampus development GO:0021766 26 12 0,000 0,03258018 0,06483699 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03258018 0,06478341 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03258018 0,06472991 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03258018 0,0646765 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03258018 0,06462318 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03258018 0,06456995 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03258018 0,06451681 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03258018 0,06446375 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03258018 0,06441078 ! drug transport GO:0015893 16 12 0,000 0,03258018 0,0643579 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03258018 0,0643051 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03258018 0,0642524 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03258018 0,06419977 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03258018 0,06414724 ! focal adhesion formation GO:0048041 35 12 0,000 0,03258018 0,06409479 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03258018 0,06404242 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03258018 0,06399014 ! forebrain cell migration GO:0021885 21 12 0,000 0,03258018 0,06393795 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03258018 0,06388584 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03258018 0,06383381 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03258018 0,06378187 ! entry into host cell GO:0030260 32 12 0,000 0,03258018 0,06373002 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03258018 0,06367825 ! monoamine transport GO:0015844 18 12 0,000 0,03258018 0,06362656 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03258018 0,06357496 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03258018 0,06352344 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03258018 0,063472 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03258018 0,06342065 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03258018 0,06336938 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03258018 0,06331819 ! protein homotetramerization GO:0051289 21 12 0,000 0,03258018 0,06326709 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03258018 0,06321607 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03258018 0,06316513 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03258018 0,06311427 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03258018 0,06306349 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03258018 0,0630128 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03258018 0,06296219 ! cranial nerve development GO:0021545 20 12 0,000 0,03258018 0,06291166 ! fucose catabolic process GO:0019317 22 12 0,000 0,03258018 0,06286121 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03258018 0,06281084 ! histone methylation GO:0016571 26 12 0,000 0,03258018 0,06276055 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03258018 0,06271034 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03258018 0,06266021 ! gland morphogenesis GO:0022612 29 12 0,000 0,03258018 0,06261016 ! T cell homeostasis GO:0043029 25 12 0,000 0,03258018 0,06256019 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03258018 0,06251031 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03258018 0,0624605 ! spleen development GO:0048536 22 12 0,000 0,03258018 0,06241077 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03258018 0,06236112 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03258018 0,06231154 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03258018 0,06226205 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03258018 0,06221264 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03258018 0,0621633 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03258018 0,06211404 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03258018 0,06206486 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03258018 0,06201576 ! response to cold GO:0009409 17 12 0,000 0,03258018 0,06196674 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03258018 0,06191779 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03258018 0,06186892 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03524738 0,06688106 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03524738 0,06682836 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03524738 0,06677574 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03524738 0,0667232 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03524738 0,06667075 ! lipid localization GO:0010876 28 13 0,000 0,03524738 0,06661837 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03524738 0,06656608 ! organelle fusion GO:0048284 32 13 0,000 0,03524738 0,06651387 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03524738 0,06646175 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03524738 0,0664097 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03524738 0,06635774 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03524738 0,06630586 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03524738 0,06625405 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03524738 0,06620233 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03524738 0,06615069 ! methionine metabolic process GO:0006555 27 13 0,000 0,03524738 0,06609913 ! plasma membrane organization GO:0007009 24 13 0,000 0,03524738 0,06604766 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03524738 0,06599626 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03524738 0,06594494 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03524738 0,0658937 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03524738 0,06584254 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03524738 0,06579146 ! response to X-ray GO:0010165 25 13 0,000 0,03524738 0,06574046 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03524738 0,06568953 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03524738 0,06563869 ! exocrine system development GO:0035272 32 13 0,000 0,03524738 0,06558793 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03524738 0,06553724 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03524738 0,06548663 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03524738 0,0654361 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03524738 0,06538565 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03524738 0,06533528 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03524738 0,06528498 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03524738 0,06523476 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03524738 0,06518462 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03524738 0,06513455 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03524738 0,06508457 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03524738 0,06503465 ! ribosome assembly GO:0042255 17 13 0,000 0,03524738 0,06498482 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03524738 0,06493506 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03524738 0,06488538 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03524738 0,06483577 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03524738 0,06478624 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03524738 0,06473679 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03524738 0,06468741 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03524738 0,0646381 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03524738 0,06458887 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03524738 0,06453972 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03524738 0,06449064 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03524738 0,06444163 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03524738 0,0643927 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03524738 0,06434385 ! insulin secretion GO:0030073 23 13 0,000 0,03524738 0,06429506 ! actin filament polymerization GO:0030041 24 13 0,000 0,03524738 0,06424636 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03524738 0,06419772 ! acrosome reaction GO:0007340 18 13 0,000 0,03524738 0,06414916 ! rRNA transcription GO:0009303 25 14 0,000 0,0379073 0,068938 ! lactation GO:0007595 26 14 0,000 0,0379073 0,06888593 ! reproductive cellular process GO:0048610 20 14 0,000 0,0379073 0,06883394 ! tRNA modification GO:0006400 20 14 0,000 0,0379073 0,06878203 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0379073 0,0687302 ! regulation of S phase GO:0033261 23 14 0,000 0,0379073 0,06867845 ! water transport GO:0006833 21 14 0,000 0,0379073 0,06862677 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0379073 0,06857517 ! non-recombinational repair GO:0000726 25 14 0,000 0,0379073 0,06852365 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0379073 0,0684722 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0379073 0,06842084 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0379073 0,06836955 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0379073 0,06831833 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0379073 0,0682672 ! palate development GO:0060021 31 14 0,000 0,0379073 0,06821614 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0379073 0,06816515 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0379073 0,06811425 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0379073 0,06806341 ! arginine metabolic process GO:0006525 17 14 0,000 0,0379073 0,06801266 ! regulation of heart rate GO:0002027 24 14 0,000 0,0379073 0,06796198 ! organic alcohol transport GO:0015850 29 14 0,000 0,0379073 0,06791137 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0379073 0,06786084 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0379073 0,06781039 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0379073 0,06776001 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0379073 0,06770971 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0379073 0,06765948 ! L-amino acid transport GO:0015807 30 14 0,000 0,0379073 0,06760932 ! bone mineralization GO:0030282 17 14 0,000 0,0379073 0,06755924 ! stem cell development GO:0048864 43 14 0,000 0,0379073 0,06750923 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0379073 0,0674593 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0379073 0,06740944 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0379073 0,06735966 ! cerebellum development GO:0021549 21 14 0,000 0,0379073 0,06730995 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0379073 0,06726031 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0379073 0,06721074 ! response to gamma radiation GO:0010332 28 14 0,000 0,0379073 0,06716125 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0379073 0,06711183 ! cofactor transport GO:0051181 26 14 0,000 0,0379073 0,06706248 ! NADP metabolic process GO:0006739 24 14 0,000 0,0379073 0,06701321 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0379073 0,06696401 ! intestinal absorption GO:0050892 25 14 0,000 0,0379073 0,06691488 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0379073 0,06686582 ! oxygen transport GO:0015671 21 14 0,000 0,0379073 0,06681683 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0379073 0,06676792 ! male genitalia development GO:0030539 24 14 0,000 0,0379073 0,06671908 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0379073 0,0666703 ! regulation of axon extension GO:0030516 37 14 0,000 0,0379073 0,0666216 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,0379073 0,06657297 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0379073 0,06652442 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04055999 0,07112779 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04055999 0,07107599 ! superoxide anion generation GO:0042554 20 15 0,000 0,04055999 0,07102426 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04055999 0,0709726 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04055999 0,07092102 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04055999 0,07086952 ! copper ion transport GO:0006825 20 15 0,000 0,04055999 0,07081809 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04055999 0,07076674 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04055999 0,07071546 ! sulfate transport GO:0008272 23 15 0,000 0,04055999 0,07066425 ! response to cAMP GO:0051591 22 15 0,000 0,04055999 0,07061312 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04055999 0,07056206 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04055999 0,07051108 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04055999 0,07046017 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04055999 0,07040933 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04055999 0,07035856 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04055999 0,07030787 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04055999 0,07025726 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04055999 0,07020671 ! pituitary gland development GO:0021983 29 15 0,000 0,04055999 0,07015624 ! vesicle coating GO:0006901 33 15 0,000 0,04055999 0,07010584 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04055999 0,07005551 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04055999 0,07000526 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04055999 0,06995507 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04055999 0,06990496 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04055999 0,06985492 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04055999 0,06980496 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04055999 0,06975506 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04055999 0,06970524 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04055999 0,06965548 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04055999 0,0696058 ! histone deacetylation GO:0016575 20 15 0,000 0,04055999 0,06955619 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04055999 0,06950664 ! tissue regeneration GO:0042246 26 15 0,000 0,04055999 0,06945717 ! water homeostasis GO:0030104 27 15 0,000 0,04055999 0,06940777 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04055999 0,06935844 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04055999 0,06930918 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04055999 0,06925999 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04055999 0,06921087 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04055999 0,06916182 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04055999 0,06911284 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04055999 0,06906393 ! detection of bacterium GO:0016045 18 15 0,000 0,04055999 0,06901508 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04055999 0,06896631 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04055999 0,06891761 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04055999 0,06886897 ! peptide hormone processing GO:0016486 23 15 0,000 0,04055999 0,0688204 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04320544 0,07325743 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04320544 0,07320584 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04320544 0,07315433 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04320544 0,07310288 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04320544 0,07305151 ! bone remodeling GO:0046849 27 16 0,000 0,04320544 0,07300021 ! filopodium assembly GO:0046847 32 16 0,000 0,04320544 0,07294898 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04320544 0,07289782 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04320544 0,07284674 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04320544 0,07279573 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04320544 0,07274478 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04320544 0,07269391 ! startle response GO:0001964 28 16 0,000 0,04320544 0,07264311 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04320544 0,07259239 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04320544 0,07254173 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04320544 0,07249114 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04320544 0,07244062 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04320544 0,07239018 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04320544 0,0723398 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04320544 0,0722895 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04320544 0,07223926 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04320544 0,07218909 ! response to osmotic stress GO:0006970 25 16 0,000 0,04320544 0,072139 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04320544 0,07208897 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04320544 0,07203901 ! fructose metabolic process GO:0006000 25 16 0,000 0,04320544 0,07198913 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04320544 0,07193931 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04320544 0,07188956 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04320544 0,07183987 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04320544 0,07179026 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04320544 0,07174072 ! axon cargo transport GO:0008088 43 16 0,000 0,04320544 0,07169124 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04320544 0,07164183 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04320544 0,07159249 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04320544 0,07154322 ! DNA replication initiation GO:0006270 27 16 0,000 0,04320544 0,07149401 ! neuron recognition GO:0008038 35 16 0,000 0,04320544 0,07144488 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04320544 0,07139581 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04320544 0,07134681 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04320544 0,07129787 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04320544 0,071249 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04320544 0,0712002 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04320544 0,07115147 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04320544 0,0711028 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04320544 0,0710542 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04320544 0,07100567 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04320544 0,0709572 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04320544 0,0709088 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04320544 0,07086046 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04320544 0,07081219 ! defense response to virus GO:0051607 37 16 0,000 0,04320544 0,07076399 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04584369 0,07503396 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04584369 0,07498295 ! metencephalon development GO:0022037 30 17 0,000 0,04584369 0,07493201 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04584369 0,07488114 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04584369 0,07483034 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04584369 0,07477961 ! signal complex assembly GO:0007172 41 17 0,000 0,04584369 0,07472895 ! endothelial cell migration GO:0043542 28 17 0,000 0,04584369 0,07467835 ! inositol metabolic process GO:0006020 28 17 0,000 0,04584369 0,07462782 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04584369 0,07457737 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04584369 0,07452698 ! glial cell development GO:0021782 27 17 0,000 0,04584369 0,07447665 ! limbic system development GO:0021761 36 17 0,000 0,04584369 0,0744264 ! adult walking behavior GO:0007628 33 17 0,000 0,04584369 0,07437621 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04584369 0,07432609 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04584369 0,07427604 ! myoblast differentiation GO:0045445 45 17 0,000 0,04584369 0,07422606 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04584369 0,07417614 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04584369 0,07412629 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04584369 0,07407651 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04584369 0,0740268 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04584369 0,07397715 ! glycine metabolic process GO:0006544 28 17 0,000 0,04584369 0,07392756 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,04584369 0,07387805 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04584369 0,0738286 ! NAD metabolic process GO:0019674 29 17 0,000 0,04584369 0,07377921 ! membrane budding GO:0006900 37 17 0,000 0,04584369 0,0737299 ! DNA integration GO:0015074 29 17 0,000 0,04584369 0,07368064 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04584369 0,07363146 ! regulation of protein binding GO:0043393 33 17 0,000 0,04584369 0,07358234 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04584369 0,07353328 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04584369 0,07348429 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04584369 0,07343537 ! genitalia development GO:0048806 30 17 0,000 0,04584369 0,07338651 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04584369 0,07333772 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04584369 0,07328899 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04584369 0,07324032 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04584369 0,07319172 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04584369 0,07314319 ! steroid catabolic process GO:0006706 31 17 0,000 0,04584369 0,07309471 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04584369 0,07304631 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04584369 0,07299796 ! gas transport GO:0015669 25 17 0,000 0,04584369 0,07294969 ! organic cation transport GO:0015695 31 17 0,000 0,04584369 0,07290147 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04584369 0,07285332 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04584369 0,07280523 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04584369 0,07275721 ! microspike assembly GO:0030035 36 17 0,000 0,04584369 0,07270925 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04584369 0,07266135 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04584369 0,07261351 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04847476 0,07673043 ! neuron maturation GO:0042551 42 18 0,000 0,04847476 0,07667999 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04847476 0,07662961 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04847476 0,07657929 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04847476 0,07652904 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04847476 0,07647886 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04847476 0,07642874 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04847476 0,07637869 ! memory GO:0007613 31 18 0,000 0,04847476 0,0763287 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04847476 0,07627878 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04847476 0,07622893 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04847476 0,07617914 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04847476 0,07612941 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04847476 0,07607975 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04847476 0,07603016 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04847476 0,07598063 ! response to retinoic acid GO:0032526 26 18 0,000 0,04847476 0,07593116 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04847476 0,07588176 ! response to fungus GO:0009620 21 18 0,000 0,04847476 0,07583242 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04847476 0,07578315 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04847476 0,07573394 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04847476 0,07568479 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04847476 0,07563571 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04847476 0,07558669 ! vitamin transport GO:0051180 27 18 0,000 0,04847476 0,07553773 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04847476 0,07548884 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04847476 0,07544001 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04847476 0,07539125 ! nerve development GO:0021675 28 18 0,000 0,04847476 0,07534255 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04847476 0,07529391 ! protein secretion GO:0009306 39 19 0,000 0,05109865 0,07931829 ! positive regulation of translation GO:0045727 30 19 0,000 0,05109865 0,07926715 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05109865 0,07921608 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05109865 0,07916507 ! skin development GO:0043588 36 19 0,000 0,05109865 0,07911413 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05109865 0,07906325 ! lipid phosphorylation GO:0046834 35 19 0,000 0,05109865 0,07901244 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05109865 0,07896169 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05109865 0,07891101 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05109865 0,07886039 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05109865 0,07880984 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05109865 0,07875935 ! cerebral cortex development GO:0021987 36 19 0,000 0,05109865 0,07870893 ! pigmentation during development GO:0048066 41 19 0,000 0,05109865 0,07865857 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05109865 0,07860828 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05109865 0,07855805 ! heme metabolic process GO:0042168 36 19 0,000 0,05109865 0,07850789 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05109865 0,07845779 ! neuromuscular junction development GO:0007528 34 19 0,000 0,05109865 0,07840775 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05109865 0,07835778 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05109865 0,07830787 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05109865 0,07825802 ! protein export from nucleus GO:0006611 36 19 0,000 0,05109865 0,07820824 ! heart process GO:0003015 30 19 0,000 0,05109865 0,07815852 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05109865 0,07810886 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05109865 0,07805927 ! visual learning GO:0008542 36 19 0,000 0,05109865 0,07800974 ! cellular pigmentation GO:0033059 36 19 0,000 0,05109865 0,07796027 ! G1 phase GO:0051318 40 19 0,000 0,05109865 0,07791087 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05109865 0,07786153 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05109865 0,07781225 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05109865 0,07776303 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05109865 0,07771388 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05109865 0,07766478 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05109865 0,07761575 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05109865 0,07756678 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05109865 0,07751788 ! cilium assembly GO:0042384 37 19 0,000 0,05109865 0,07746903 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05109865 0,07742025 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0537154 0,08133369 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0537154 0,08128254 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0537154 0,08123145 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0537154 0,08118043 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0537154 0,08112947 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0537154 0,08107857 ! response to vitamin GO:0033273 31 20 0,000 0,0537154 0,08102774 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0537154 0,08097697 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0537154 0,08092626 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0537154 0,08087562 ! response to alkaloid GO:0043279 38 20 0,000 0,0537154 0,08082504 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0537154 0,08077453 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0537154 0,08072407 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,0537154 0,08067368 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0537154 0,08062336 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0537154 0,08057309 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0537154 0,08052289 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,0537154 0,08047275 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0537154 0,08042268 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0537154 0,08037266 ! body fluid secretion GO:0007589 31 20 0,000 0,0537154 0,08032271 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0537154 0,08027282 ! peptide secretion GO:0002790 35 20 0,000 0,0537154 0,08022299 ! stem cell differentiation GO:0048863 53 20 0,000 0,0537154 0,08017323 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0537154 0,08012352 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0537154 0,08007388 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0537154 0,0800243 ! sensory perception of pain GO:0019233 30 20 0,000 0,0537154 0,07997478 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0537154 0,07992532 ! diencephalon development GO:0021536 34 20 0,000 0,0537154 0,07987592 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0537154 0,07982658 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0537154 0,07977731 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0537154 0,07972809 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0537154 0,07967894 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0537154 0,07962985 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0537154 0,07958081 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0537154 0,07953184 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0537154 0,07948293 ! regulation of glucose import GO:0046324 29 20 0,000 0,0537154 0,07943408 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0537154 0,07938528 ! actin filament-based movement GO:0030048 43 20 0,000 0,0537154 0,07933655 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0537154 0,07928788 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,0537154 0,07923926 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0537154 0,07919071 ! negative regulation of translation GO:0017148 29 20 0,000 0,0537154 0,07914222 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0537154 0,07909378 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0537154 0,07904541 ! regulation of cell killing GO:0031341 42 21 0,000 0,05632501 0,08283495 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05632501 0,08278435 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05632501 0,08273381 ! hormone secretion GO:0046879 38 21 0,000 0,05632501 0,08268333 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05632501 0,08263291 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05632501 0,08258256 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05632501 0,08253226 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05632501 0,08248203 ! axis specification GO:0009798 38 21 0,000 0,05632501 0,08243186 ! ovarian follicle development GO:0001541 35 21 0,000 0,05632501 0,08238175 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05632501 0,0823317 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05632501 0,08228171 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05632501 0,08223178 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05632501 0,08218191 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05632501 0,08213211 ! cell aging GO:0007569 44 21 0,000 0,05632501 0,08208236 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05632501 0,08203267 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05632501 0,08198305 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05632501 0,08193348 ! cytolysis GO:0019835 24 21 0,000 0,05632501 0,08188397 ! vasodilation GO:0042311 39 21 0,000 0,05632501 0,08183453 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05632501 0,08178514 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05632501 0,08173581 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05632501 0,08168654 ! oogenesis GO:0048477 36 21 0,000 0,05632501 0,08163734 ! DNA modification GO:0006304 34 21 0,000 0,05632501 0,08158819 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05632501 0,0815391 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05632501 0,08149006 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05632501 0,08144109 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05632501 0,08139218 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05632501 0,08134332 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05632501 0,08129453 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05632501 0,08124579 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05632501 0,08119711 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05632501 0,08114849 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05632501 0,08109993 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05632501 0,08105142 ! gut development GO:0048565 39 21 0,000 0,05632501 0,08100298 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05892752 0,08469511 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05892752 0,08464454 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05892752 0,08459404 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05892752 0,08454359 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05892752 0,08449321 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05892752 0,08444289 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,05892752 0,08439262 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05892752 0,08434242 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05892752 0,08429228 ! regeneration GO:0031099 41 22 0,000 0,05892752 0,08424219 ! keratinization GO:0031424 28 22 0,000 0,05892752 0,08419217 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05892752 0,0841422 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05892752 0,08409229 ! sensory perception of taste GO:0050909 28 22 0,000 0,05892752 0,08404245 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,05892752 0,08399266 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05892752 0,08394293 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05892752 0,08389326 ! vacuolar transport GO:0007034 36 22 0,000 0,05892752 0,08384365 ! lysosome organization GO:0007040 41 22 0,000 0,05892752 0,08379409 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05892752 0,0837446 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05892752 0,08369516 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05892752 0,08364579 ! fucose metabolic process GO:0006004 39 22 0,000 0,05892752 0,08359647 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05892752 0,08354721 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05892752 0,083498 ! ureteric bud development GO:0001657 43 22 0,000 0,05892752 0,08344886 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05892752 0,08339977 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05892752 0,08335074 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05892752 0,08330177 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05892752 0,08325285 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05892752 0,08320399 ! sarcomere organization GO:0045214 30 22 0,000 0,05892752 0,08315519 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,05892752 0,08310645 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05892752 0,08305777 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05892752 0,08300914 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05892752 0,08296057 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05892752 0,08291205 ! protein stabilization GO:0050821 39 22 0,000 0,05892752 0,08286359 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,06152293 0,08646272 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06152293 0,08641225 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,06152293 0,08636183 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06152293 0,08631147 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06152293 0,08626117 ! gluconeogenesis GO:0006094 33 23 0,000 0,06152293 0,08621094 ! viral genome replication GO:0019079 41 23 0,000 0,06152293 0,08616075 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06152293 0,08611063 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06152293 0,08606057 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06152293 0,08601056 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06152293 0,08596061 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06152293 0,08591072 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06152293 0,08586089 ! visual behavior GO:0007632 42 23 0,000 0,06152293 0,08581112 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06152293 0,0857614 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06152293 0,08571174 ! response to ethanol GO:0045471 46 23 0,000 0,06152293 0,08566214 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06152293 0,08561259 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06152293 0,08556311 ! peroxisome organization GO:0007031 37 23 0,000 0,06152293 0,08551368 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06152293 0,0854643 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06152293 0,08541499 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06152293 0,08536573 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06152293 0,08531653 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,06152293 0,08526738 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06152293 0,08521829 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06152293 0,08516926 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06152293 0,08512029 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06152293 0,08507137 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06152293 0,0850225 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06152293 0,08497369 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06152293 0,08492494 ! fatty acid transport GO:0015908 44 23 0,000 0,06152293 0,08487625 ! platelet activation GO:0030168 37 23 0,000 0,06152293 0,08482761 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06152293 0,08477902 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06152293 0,0847305 ! hormone transport GO:0009914 40 23 0,000 0,06152293 0,08468202 ! cell-cell recognition GO:0009988 25 23 0,000 0,06152293 0,08463361 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06152293 0,08458524 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06152293 0,08453694 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06152293 0,08448868 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06152293 0,08444049 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06152293 0,08439235 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06411128 0,08789272 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,06411128 0,08784267 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06411128 0,08779267 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06411128 0,08774274 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06411128 0,08769285 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06411128 0,08764303 ! vesicle docking GO:0048278 47 24 0,000 0,06411128 0,08759326 ! spinal cord development GO:0021510 47 24 0,000 0,06411128 0,08754355 ! vacuole organization GO:0007033 43 24 0,000 0,06411128 0,08749389 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06411128 0,08744429 ! digestive system process GO:0022600 39 24 0,000 0,06411128 0,08739475 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06411128 0,08734526 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06411128 0,08729583 ! regulation of behavior GO:0050795 43 24 0,000 0,06411128 0,08724645 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06411128 0,08719713 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06411128 0,08714787 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06411128 0,08709866 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06411128 0,08704951 ! membrane depolarization GO:0051899 39 24 0,000 0,06411128 0,08700041 ! pallium development GO:0021543 49 24 0,000 0,06411128 0,08695137 ! pentose metabolic process GO:0019321 35 24 0,000 0,06411128 0,08690238 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06411128 0,08685345 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06411128 0,08680457 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06411128 0,08675575 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06411128 0,08670699 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06411128 0,08665827 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06411128 0,08660962 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06411128 0,08656102 ! regulation of amine transport GO:0051952 40 24 0,000 0,06411128 0,08651247 ! protein tetramerization GO:0051262 52 24 0,000 0,06411128 0,08646397 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06669257 0,08989485 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,06669257 0,08984452 ! myelination GO:0042552 45 25 0,000 0,06669257 0,08979424 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06669257 0,08974402 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06669257 0,08969386 ! phototransduction GO:0007602 33 25 0,000 0,06669257 0,08964375 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06669257 0,0895937 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06669257 0,0895437 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,06669257 0,08949376 ! sperm motility GO:0030317 31 25 0,000 0,06669257 0,08944388 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06669257 0,08939405 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,06669257 0,08934427 ! receptor metabolic process GO:0043112 46 25 0,000 0,06669257 0,08929455 ! chromosome condensation GO:0030261 45 25 0,000 0,06669257 0,08924489 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06669257 0,08919528 ! negative regulation of cell development GO:0010721 73 25 0,000 0,06669257 0,08914573 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06669257 0,08909623 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06669257 0,08904679 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06669257 0,0889974 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06669257 0,08894807 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06669257 0,08889879 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,06669257 0,08884956 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06669257 0,08880039 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06669257 0,08875128 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06669257 0,08870222 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06669257 0,08865321 ! telomere organization GO:0032200 43 25 0,000 0,06669257 0,08860426 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06669257 0,08855536 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06669257 0,08850652 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06926682 0,09187209 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06926682 0,09182147 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06926682 0,09177091 ! initiation of viral infection GO:0019059 57 26 0,000 0,06926682 0,0917204 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06926682 0,09166995 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06926682 0,09161956 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06926682 0,09156922 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06926682 0,09151893 ! tube lumen formation GO:0035148 50 26 0,000 0,06926682 0,0914687 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06926682 0,09141853 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,06926682 0,09136841 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06926682 0,09131834 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,06926682 0,09126833 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,06926682 0,09121838 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06926682 0,09116848 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06926682 0,09111863 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06926682 0,09106884 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06926682 0,0910191 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06926682 0,09096942 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06926682 0,09091979 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06926682 0,09087021 ! blastocyst development GO:0001824 49 26 0,000 0,06926682 0,09082069 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06926682 0,09077123 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06926682 0,09072181 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,07183406 0,09403306 ! neuron fate commitment GO:0048663 48 27 0,000 0,07183406 0,09398192 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,07183406 0,09393085 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07183406 0,09387982 ! iron ion transport GO:0006826 59 27 0,000 0,07183406 0,09382886 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,07183406 0,09377795 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07183406 0,09372709 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07183406 0,09367629 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07183406 0,09362554 ! fat cell differentiation GO:0045444 50 27 0,000 0,07183406 0,09357485 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07183406 0,09352422 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,07183406 0,09347364 ! autophagy GO:0006914 41 27 0,000 0,07183406 0,09342311 ! male gonad development GO:0008584 44 27 0,000 0,07183406 0,09337264 ! response to toxin GO:0009636 47 27 0,000 0,07183406 0,09332222 ! primary neural tube formation GO:0014020 51 27 0,000 0,07183406 0,09327186 ! base-excision repair GO:0006284 41 27 0,000 0,07183406 0,09322155 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07183406 0,0931713 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07183406 0,0931211 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07183406 0,09307095 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07183406 0,09302086 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07183406 0,09297082 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07183406 0,09292084 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07183406 0,09287091 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,07183406 0,09282103 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07439431 0,09607767 ! circadian rhythm GO:0007623 50 28 0,000 0,07439431 0,09602613 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07439431 0,09597464 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,07439431 0,09592321 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07439431 0,09587183 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07439431 0,09582051 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07439431 0,09576924 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07439431 0,09571802 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07439431 0,09566687 ! synaptogenesis GO:0007416 42 28 0,000 0,07439431 0,09561576 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,07439431 0,09556471 ! lipid oxidation GO:0034440 43 28 0,000 0,07439431 0,09551372 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07439431 0,09546278 ! translational initiation GO:0006413 65 29 0,000 0,07694758 0,0986865 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07694758 0,09863392 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07694758 0,0985814 ! regulation of pH GO:0006885 43 29 0,000 0,07694758 0,09852893 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07694758 0,09847653 ! catechol metabolic process GO:0009712 54 29 0,000 0,07694758 0,09842417 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07694758 0,09837187 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07694758 0,09831963 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07694758 0,09826745 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07694758 0,09821531 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07694758 0,09816324 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07694758 0,09811122 ! cell fate determination GO:0001709 60 29 0,000 0,07694758 0,09805925 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07694758 0,09800734 ! detection of light stimulus GO:0009583 38 29 0,000 0,07694758 0,09795549 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,07694758 0,09790368 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07694758 0,09785194 ! tissue homeostasis GO:0001894 48 29 0,000 0,07694758 0,09780025 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07694758 0,09774861 ! phenol metabolic process GO:0018958 55 30 0,000 0,07949389 0,10092997 ! zinc ion transport GO:0006829 45 30 0,000 0,07949389 0,10087673 ! membrane docking GO:0022406 61 30 0,000 0,07949389 0,10082356 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07949389 0,10077044 ! cell junction assembly GO:0034329 78 30 0,000 0,07949389 0,10071737 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07949389 0,10066436 ! myofibril assembly GO:0030239 47 30 0,000 0,07949389 0,10061141 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07949389 0,10055851 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07949389 0,10050567 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07949389 0,10045288 ! phospholipid transport GO:0015914 51 30 0,000 0,07949389 0,10040015 ! ensheathment of neurons GO:0007272 57 30 0,000 0,07949389 0,10034748 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07949389 0,10029485 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07949389 0,10024229 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,07949389 0,10018978 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07949389 0,10013732 ! eye morphogenesis GO:0048592 60 30 0,000 0,07949389 0,10008492 ! regulation of B cell activation GO:0050864 50 30 0,000 0,07949389 0,10003258 ! response to heat GO:0009408 50 30 0,000 0,07949389 0,09998029 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08203325 0,10312017 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,08203325 0,10306632 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08203325 0,10301253 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08203325 0,1029588 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08203325 0,10290511 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08203325 0,10285149 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08203325 0,10279792 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08203325 0,10274441 ! ovulation cycle process GO:0022602 49 31 0,000 0,08203325 0,10269095 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08203325 0,10263755 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08203325 0,1025842 ! peptide transport GO:0015833 55 31 0,000 0,08203325 0,10253091 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08203325 0,10247768 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08203325 0,1024245 ! natural killer cell activation GO:0030101 45 31 0,000 0,08203325 0,10237137 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08203325 0,1023183 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08203325 0,10226529 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08203325 0,10221233 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,08203325 0,10215943 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08203325 0,10210658 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0845657 0,10520428 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0845657 0,10514991 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0845657 0,1050956 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0845657 0,10504134 ! cholesterol transport GO:0030301 56 32 0,000 0,0845657 0,10498714 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0845657 0,104933 ! spliceosome assembly GO:0000245 67 32 0,000 0,0845657 0,10487891 ! spindle organization GO:0007051 46 32 0,000 0,0845657 0,10482487 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0845657 0,1047709 ! metanephros development GO:0001656 74 32 0,000 0,0845657 0,10471697 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0845657 0,10466311 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0845657 0,1046093 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0845657 0,10455554 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0845657 0,10450184 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0845657 0,10444819 ! muscle cell development GO:0055001 49 32 0,000 0,0845657 0,1043946 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0845657 0,10434107 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0845657 0,10428759 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0845657 0,10423416 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0845657 0,10418079 ! ovulation cycle GO:0042698 51 32 0,000 0,0845657 0,10412747 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0845657 0,10407421 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0845657 0,104021 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0845657 0,10396785 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,08709125 0,10701815 ! post-embryonic development GO:0009791 69 33 0,000 0,08709125 0,10696352 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08709125 0,10690895 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08709125 0,10685443 ! cell fate specification GO:0001708 52 33 0,000 0,08709125 0,10679997 ! sterol transport GO:0015918 57 33 0,000 0,08709125 0,10674557 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,08709125 0,10669121 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08709125 0,10663692 ! adult locomotory behavior GO:0008344 59 33 0,000 0,08709125 0,10658268 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,08709125 0,10652849 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08709125 0,10647436 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08960991 0,10949794 ! glial cell differentiation GO:0010001 63 34 0,000 0,08960991 0,10944236 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08960991 0,10938683 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08960991 0,10933136 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08960991 0,10927595 ! mismatch repair GO:0006298 46 34 0,000 0,08960991 0,10922059 ! spermatid development GO:0007286 63 34 0,000 0,08960991 0,10916529 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08960991 0,10911004 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08960991 0,10905485 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,09212171 0,11205502 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,09212171 0,1119984 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,09212171 0,11194183 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,09212171 0,11188532 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,09212171 0,11182887 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,09212171 0,11177248 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,09212171 0,11171614 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,09212171 0,11165986 ! cytokine production GO:0001816 59 35 0,000 0,09212171 0,11160364 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,09212171 0,11154747 ! neural tube formation GO:0001841 67 35 0,000 0,09212171 0,11149136 ! vesicle localization GO:0051648 64 35 0,000 0,09212171 0,11143531 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,09462666 0,11440791 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,09462666 0,11435045 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,09462666 0,11429304 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,09462666 0,11423569 ! cell junction organization GO:0034330 86 36 0,000 0,09462666 0,1141784 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,09462666 0,11412117 ! positive regulation of cell development GO:0010720 80 36 0,000 0,09462666 0,114064 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,09462666 0,11400688 ! regulation of proteolysis GO:0030162 72 36 0,000 0,09462666 0,11394982 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,09462666 0,11389281 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,09462666 0,11383587 ! aerobic respiration GO:0009060 55 36 0,000 0,09462666 0,11377898 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,09462666 0,11372215 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,09462666 0,11366537 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,09462666 0,11360865 ! RNA export from nucleus GO:0006405 56 37 0,000 0,09712478 0,11654973 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,09712478 0,11649163 ! meiosis I GO:0007127 65 37 0,000 0,09712478 0,11643359 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,09712478 0,11637561 ! sister chromatid segregation GO:0000819 58 37 0,000 0,09712478 0,11631768 ! actomyosin structure organization GO:0031032 62 37 0,000 0,09712478 0,11625981 ! organic anion transport GO:0015711 68 37 0,000 0,09712478 0,116202 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,09712478 0,11614424 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,09712478 0,11608655 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,09712478 0,11602891 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,09712478 0,11597132 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,09712478 0,1159138 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,09712478 0,11585633 ! pigment metabolic process GO:0042440 80 37 0,000 0,09712478 0,11579892 ! spermatid differentiation GO:0048515 66 37 0,000 0,09712478 0,11574156 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,09712478 0,11568427 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,09961609 0,11859293 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,09961609 0,11853428 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,09961609 0,11847569 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,09961609 0,11841715 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,09961609 0,11835867 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,09961609 0,11830025 ! nucleus organization GO:0006997 67 38 0,000 0,09961609 0,11824189 ! lipid homeostasis GO:0055088 67 38 0,000 0,09961609 0,11818359 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,09961609 0,11812534 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,09961609 0,11806715 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,09961609 0,11800902 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,09961609 0,11795094 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,09961609 0,11789292 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,09961609 0,11783496 ! mRNA catabolic process GO:0006402 71 39 0,000 0,10210061 0,12071453 ! mammary gland development GO:0030879 86 39 0,000 0,10210061 0,12065524 ! learning GO:0007612 77 39 0,000 0,10210061 0,12059601 ! ear morphogenesis GO:0042471 60 39 0,000 0,10210061 0,12053683 ! organic ether metabolic process GO:0018904 55 39 0,000 0,10210061 0,12047772 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,10210061 0,12041866 ! ion transmembrane transport GO:0034220 66 39 0,000 0,10210061 0,12035966 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,10210061 0,12030072 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,10210061 0,12024183 ! RNA modification GO:0009451 57 39 0,000 0,10210061 0,12018301 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,10210061 0,12012424 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,10457836 0,12297924 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,10457836 0,12291916 ! feeding behavior GO:0007631 59 40 0,000 0,10457836 0,12285914 ! negative regulation of binding GO:0051100 72 40 0,000 0,10457836 0,12279918 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,10457836 0,12273928 ! maintenance of protein location GO:0045185 91 40 0,000 0,10457836 0,12267944 ! cytokinesis GO:0000910 72 40 0,000 0,10457836 0,12261965 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,10704935 0,12545579 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,10704935 0,12539471 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,10704935 0,12533369 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,10704935 0,12527273 ! gliogenesis GO:0042063 88 41 0,000 0,10704935 0,12521183 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,10704935 0,12515099 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,10704935 0,1250902 ! T cell differentiation GO:0030217 81 41 0,000 0,10704935 0,12502948 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,10704935 0,12496881 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,10704935 0,12490821 ! female gamete generation GO:0007292 61 41 0,000 0,10704935 0,12484766 ! polyol metabolic process GO:0019751 66 41 0,000 0,10704935 0,12478717 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,10704935 0,12472674 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,1095136 0,12753617 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,1095136 0,12747447 ! regulation of tube size GO:0035150 71 42 0,000 0,1095136 0,12741283 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,1095136 0,12735124 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,1095136 0,12728972 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,1095136 0,12722826 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,1095136 0,12716685 ! neuron migration GO:0001764 79 42 0,000 0,1095136 0,12710551 ! regulation of protein secretion GO:0050708 71 42 0,000 0,1095136 0,12704422 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,11197114 0,12983256 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,11197114 0,12977002 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,11197114 0,12970754 ! glucose transport GO:0015758 65 43 0,000 0,11197114 0,12964512 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,11197114 0,12958276 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,11197114 0,12952046 ! neural tube development GO:0021915 77 43 0,000 0,11197114 0,12945822 ! striated muscle contraction GO:0006941 77 43 0,000 0,11197114 0,12939604 ! phagocytosis GO:0006909 90 43 0,000 0,11197114 0,12933392 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,11197114 0,12927186 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,11442197 0,13203801 ! hexose transport GO:0008645 67 44 0,000 0,11442197 0,13197472 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,11442197 0,13191148 ! double-strand break repair GO:0006302 81 44 0,000 0,11442197 0,1318483 ! biopolymer methylation GO:0043414 84 44 0,000 0,11442197 0,13178519 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,11442197 0,13172213 ! developmental growth GO:0048589 82 44 0,000 0,11442197 0,13165914 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,11686612 0,13440721 ! glycolysis GO:0006096 65 45 0,000 0,11686612 0,134343 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,11686612 0,13427884 ! leukocyte migration GO:0050900 68 45 0,000 0,11686612 0,13421474 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,11686612 0,13415071 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,11686612 0,13408674 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,11686612 0,13402283 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,11686612 0,13395898 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,11686612 0,13389519 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,11686612 0,13383146 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,11686612 0,13376779 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,11686612 0,13370418 ! cell growth GO:0016049 84 45 0,000 0,11686612 0,13364063 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,11930361 0,13636317 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,11930361 0,13629842 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,11930361 0,13623374 ! pigmentation GO:0043473 100 46 0,000 0,11930361 0,13616911 ! response to insulin stimulus GO:0032868 95 46 0,000 0,11930361 0,13610454 ! positive regulation of defense response GO:0031349 76 47 0,000 0,12173445 0,13881189 ! response to calcium ion GO:0051592 81 47 0,000 0,12173445 0,13874613 ! endosome transport GO:0016197 108 47 0,000 0,12173445 0,13868044 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,12173445 0,13861481 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,12173445 0,13854924 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,12173445 0,13848373 ! methylation GO:0032259 90 47 0,000 0,12173445 0,13841828 ! protein homooligomerization GO:0051260 76 47 0,000 0,12173445 0,1383529 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,12415866 0,14104142 ! mitochondrial transport GO:0006839 82 48 0,000 0,12415866 0,14097486 ! Notch signaling pathway GO:0007219 96 48 0,000 0,12415866 0,14090837 ! cellular component disassembly GO:0022411 86 48 0,000 0,12415866 0,14084193 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,12415866 0,14077556 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,12415866 0,14070925 ! activation of caspase activity GO:0006919 84 48 0,000 0,12415866 0,140643 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,12415866 0,14057682 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,12415866 0,1405107 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,12415866 0,14044463 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,12415866 0,14037864 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,12657626 0,14304485 ! regulation of action potential GO:0001508 95 49 0,000 0,12657626 0,14297769 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,12657626 0,1429106 ! regulation of ion transport GO:0043269 77 49 0,000 0,12657626 0,14284357 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,12657626 0,1427766 ! peptide metabolic process GO:0006518 76 49 0,000 0,12657626 0,14270969 ! response to temperature stimulus GO:0009266 76 49 0,000 0,12657626 0,14264285 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,12657626 0,14257607 ! endocrine system development GO:0035270 104 49 0,000 0,12657626 0,14250935 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,12657626 0,1424427 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,12657626 0,1423761 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,12657626 0,14230957 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,12657626 0,1422431 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,12898727 0,14488486 ! neuromuscular process GO:0050905 99 50 0,000 0,12898727 0,14481725 ! inner ear development GO:0048839 79 50 0,000 0,12898727 0,14474971 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,12898727 0,14468222 ! viral infectious cycle GO:0019058 99 51 0,000 0,1313917 0,14731055 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,1313917 0,14724193 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1313917 0,14717339 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,1313917 0,1471049 ! excretion GO:0007588 83 51 0,000 0,1313917 0,14703648 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1313917 0,14696812 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1313917 0,14689983 ! vesicle organization GO:0016050 107 51 0,000 0,1313917 0,1468316 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,1313917 0,14676343 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,1313917 0,14669533 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,13378958 0,14930321 ! membrane fusion GO:0006944 110 52 0,000 0,13378958 0,14923399 ! positive regulation of growth GO:0045927 90 52 0,000 0,13378958 0,14916484 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,13378958 0,14909575 ! amino acid activation GO:0043038 92 52 0,000 0,13378958 0,14902672 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,13378958 0,14895776 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,13618091 0,15155008 ! RNA catabolic process GO:0006401 93 53 0,000 0,13618091 0,15148001 ! regulation of translational initiation GO:0006446 82 53 0,000 0,13618091 0,15141001 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,13618091 0,15134008 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,13618091 0,15127021 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,13618091 0,1512004 ! cell maturation GO:0048469 100 53 0,000 0,13618091 0,15113066 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,13618091 0,15106098 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,13618091 0,15099137 ! response to UV GO:0009411 104 53 0,000 0,13618091 0,15092182 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,13856572 0,15349407 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,13856572 0,15342344 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,13856572 0,15335286 ! cell recognition GO:0008037 85 54 0,000 0,13856572 0,15328236 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,13856572 0,15321191 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,13856572 0,15314154 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,13856572 0,15307122 ! chloride transport GO:0006821 90 55 0,000 0,14094403 0,15562705 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,14094403 0,15555566 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,14094403 0,15548433 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,14094403 0,15541308 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,14094403 0,15534188 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,14094403 0,15527076 ! aging GO:0007568 103 55 0,000 0,14094403 0,15519969 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,14094403 0,1551287 ! RNA elongation GO:0006354 79 55 0,000 0,14094403 0,15505776 ! nuclear export GO:0051168 97 55 0,000 0,14094403 0,1549869 ! regulation of actin filament length GO:0030832 105 56 0,000 0,14331585 0,15752304 ! sensory perception of smell GO:0007608 80 56 0,000 0,14331585 0,15745111 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,14331585 0,15737925 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,14331585 0,15730745 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,14331585 0,15723572 ! regulation of DNA replication GO:0006275 101 56 0,000 0,14331585 0,15716405 ! proton transport GO:0015992 94 56 0,000 0,14331585 0,15709245 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,14331585 0,15702092 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,1456812 0,15953981 ! muscle fiber development GO:0048747 112 57 0,000 0,1456812 0,15946723 ! lipid modification GO:0030258 97 57 0,000 0,1456812 0,15939471 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,1456812 0,15932226 ! hydrogen transport GO:0006818 97 58 0,000 0,1480401 0,16182847 ! regulation of endocytosis GO:0030100 91 58 0,000 0,1480401 0,16175498 ! adult behavior GO:0030534 99 58 0,000 0,1480401 0,16168156 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,1480401 0,1616082 ! positive regulation of secretion GO:0051047 95 59 0,000 0,15039256 0,16410181 ! regulation of cellular component size GO:0032535 109 59 0,000 0,15039256 0,16402742 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,15039256 0,1639531 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,15039256 0,16387885 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,15039256 0,16380466 ! DNA catabolic process GO:0006308 86 59 0,000 0,15039256 0,16373054 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,15039256 0,16365649 ! establishment of organelle localization GO:0051656 109 59 0,000 0,15039256 0,1635825 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1527386 0,16605923 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,1527386 0,16598423 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1527386 0,16590929 ! regulation of heart contraction GO:0008016 110 60 0,000 0,1527386 0,16583442 ! camera-type eye development GO:0043010 116 60 0,000 0,1527386 0,16575962 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,1527386 0,16568489 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,1527386 0,16561022 ! kidney development GO:0001822 122 60 0,000 0,1527386 0,16553562 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,15507825 0,16799562 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,15507825 0,16792001 ! tRNA processing GO:0008033 89 61 0,000 0,15507825 0,16784447 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,15507825 0,167769 ! ear development GO:0043583 103 62 0,000 0,15741151 0,17021667 ! viral reproductive process GO:0022415 126 62 0,000 0,15741151 0,1701402 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,15741151 0,1700638 ! regulation of mitosis GO:0007088 105 63 0,000 0,1597384 0,17250027 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,1597384 0,17242288 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,1597384 0,17234556 ! detection of external stimulus GO:0009581 91 63 0,000 0,1597384 0,17226831 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,1597384 0,17219113 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,1597384 0,17211402 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,16205895 0,17453618 ! cell redox homeostasis GO:0045454 102 64 0,000 0,16205895 0,17445809 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,16205895 0,17438007 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,16205895 0,17430212 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,16205895 0,17422423 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,16437317 0,17663325 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,16437317 0,17655439 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,16437317 0,17647561 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,16437317 0,17639689 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,16437317 0,17631825 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,16668107 0,17871419 ! actin filament organization GO:0007015 148 66 0,000 0,16668107 0,17863459 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,16668107 0,17855505 ! secondary metabolic process GO:0019748 116 66 0,000 0,16668107 0,17847559 ! developmental maturation GO:0021700 116 66 0,000 0,16668107 0,1783962 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,16898267 0,18077915 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,16898267 0,1806988 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,16898267 0,18061853 ! chromosome segregation GO:0007059 113 67 0,000 0,16898267 0,18053832 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,16898267 0,18045819 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,16898267 0,18037813 ! hexose catabolic process GO:0019320 104 67 0,000 0,16898267 0,18029814 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,16898267 0,18021822 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,16898267 0,18013837 ! adaptive immune response GO:0002250 119 67 0,000 0,16898267 0,18005859 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,16898267 0,17997889 ! amino acid transport GO:0006865 125 68 0,000 0,17127799 0,18234285 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,17127799 0,18226221 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,17127799 0,18218163 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,17127799 0,18210113 ! viral reproduction GO:0016032 134 68 0,000 0,17127799 0,18202069 ! regulation of lipase activity GO:0060191 130 68 0,000 0,17127799 0,18194033 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,17127799 0,18186004 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,17127799 0,18177982 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,17356705 0,18412801 ! negative regulation of cell size GO:0045792 134 69 0,000 0,17356705 0,18404686 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,17356705 0,18396578 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,17356705 0,18388478 ! urogenital system development GO:0001655 137 69 0,000 0,17356705 0,18380384 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,17356705 0,18372298 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,17356705 0,18364218 ! antigen processing and presentation GO:0019882 104 69 0,000 0,17356705 0,18356146 ! appendage morphogenesis GO:0035107 135 70 0,000 0,17584986 0,18589401 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,17812645 0,18821793 ! appendage development GO:0048736 136 71 0,000 0,17812645 0,18813531 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,17812645 0,18805275 ! regulation of immune effector process GO:0002697 137 71 0,000 0,17812645 0,18797027 ! regulation of caspase activity GO:0043281 122 72 0,000 0,18039681 0,19028265 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,18039681 0,19019927 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,18039681 0,19011596 ! carbohydrate transport GO:0008643 110 72 0,000 0,18039681 0,19003272 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,18039681 0,18994956 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,18039681 0,18986646 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,18039681 0,18978344 ! learning or memory GO:0007611 147 73 0,000 0,18266099 0,19208144 ! regulation of blood pressure GO:0008217 125 73 0,000 0,18266099 0,19199752 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,18266099 0,19191368 ! axon guidance GO:0007411 139 73 0,000 0,18266099 0,19182991 ! fertilization GO:0009566 90 73 0,000 0,18266099 0,19174622 ! transition metal ion transport GO:0000041 126 74 0,000 0,18491898 0,19403186 ! neurotransmitter transport GO:0006836 123 74 0,000 0,18491898 0,19394728 ! meiosis GO:0007126 121 74 0,000 0,18491898 0,19386277 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,18491898 0,19377834 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,18491898 0,19369398 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,18491898 0,19360969 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,18491898 0,19352547 ! eye development GO:0001654 143 74 0,000 0,18491898 0,19344133 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,18717081 0,19571185 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,18717081 0,19562683 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,18717081 0,19554189 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,18717081 0,19545702 ! meiotic cell cycle GO:0051321 122 75 0,000 0,18717081 0,19537222 ! rhythmic process GO:0048511 128 75 0,000 0,18717081 0,1952875 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,18941649 0,1975449 ! defense response to bacterium GO:0042742 89 76 0,000 0,18941649 0,19745931 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,18941649 0,19737379 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,18941649 0,19728835 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,19165605 0,19953459 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,19165605 0,19944829 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,19165605 0,19936206 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,19165605 0,19927591 ! blood coagulation GO:0007596 146 78 0,000 0,19388949 0,20151106 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,19388949 0,20142405 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,19388949 0,20133712 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,19388949 0,20125026 ! protein oligomerization GO:0051259 139 78 0,000 0,19388949 0,20116348 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,19611683 0,20338668 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,19611683 0,20329905 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,19611683 0,2032115 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,19611683 0,20312402 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,19611683 0,20303662 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,19611683 0,20294929 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,19833809 0,2051597 ! response to metal ion GO:0010038 140 80 0,000 0,19833809 0,20507153 ! muscle cell differentiation GO:0042692 159 80 0,000 0,19833809 0,20498344 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,19833809 0,20489543 ! protein import into nucleus GO:0006606 158 80 0,000 0,19833809 0,20480749 ! inorganic anion transport GO:0015698 138 80 0,000 0,19833809 0,20471963 ! T cell activation GO:0042110 168 81 0,000 0,20055329 0,20691733 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,20055329 0,20682864 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,20055329 0,20674003 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,20055329 0,20665149 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,20055329 0,20656302 ! nuclear import GO:0051170 161 81 0,000 0,20055329 0,20647464 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,20055329 0,20638632 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,20276244 0,20857052 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,20276244 0,20848139 ! response to drug GO:0042493 143 82 0,000 0,20276244 0,20839233 ! response to nutrient GO:0007584 125 82 0,000 0,20276244 0,20830335 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,20276244 0,20821444 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,20276244 0,20812561 ! regulation of lyase activity GO:0051339 160 83 0,000 0,20496556 0,21029729 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,20716267 0,21246095 ! hemostasis GO:0007599 158 84 0,000 0,20716267 0,21237042 ! regulation of ligase activity GO:0051340 142 84 0,000 0,20716267 0,21227998 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,20716267 0,21218961 ! response to unfolded protein GO:0006986 131 85 0,000 0,20935378 0,21434263 ! nucleosome assembly GO:0006334 122 85 0,000 0,20935378 0,21425146 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,20935378 0,21416037 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,20935378 0,21406935 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,2115389 0,21621181 ! response to inorganic substance GO:0010035 153 86 0,000 0,2115389 0,21612 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,2115389 0,21602827 ! chromatin assembly GO:0031497 124 86 0,000 0,2115389 0,21593661 ! tube morphogenesis GO:0035239 176 86 0,000 0,2115389 0,21584504 ! mitochondrion organization GO:0007005 148 86 0,000 0,2115389 0,21575354 ! alcohol catabolic process GO:0046164 130 86 0,000 0,2115389 0,21566212 ! amine transport GO:0015837 155 86 0,000 0,2115389 0,21557077 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,21371806 0,21769926 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,21371806 0,21760713 ! protein localization in nucleus GO:0034504 176 87 0,000 0,21371806 0,21751508 ! cellular respiration GO:0045333 135 88 0,000 0,21589126 0,21963399 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,21589126 0,21954116 ! gland development GO:0048732 206 88 0,000 0,21589126 0,21944841 ! regulation of neurological system process GO:0031644 148 88 0,000 0,21589126 0,21935574 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,21589126 0,21926314 ! cellular defense response GO:0006968 114 89 0,000 0,21805854 0,22137082 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,21805854 0,22127745 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,22021989 0,2233765 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,22021989 0,22328237 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,22021989 0,22318831 ! sterol metabolic process GO:0016125 152 91 0,000 0,22237534 0,22527793 ! response to protein stimulus GO:0051789 149 91 0,000 0,22237534 0,22518311 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,22237534 0,22508838 ! regulation of defense response GO:0031347 149 92 0,000 0,22452491 0,2271686 ! nucleosome organization GO:0034728 138 92 0,000 0,22452491 0,22707311 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,22452491 0,2269777 ! vitamin metabolic process GO:0006766 139 92 0,000 0,22452491 0,22688237 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,2266686 0,22895242 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,2266686 0,22885634 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,2266686 0,22876034 ! regulation of membrane potential GO:0042391 164 93 0,000 0,2266686 0,22866443 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,2266686 0,22856859 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,22880644 0,23062769 ! female pregnancy GO:0007565 164 94 0,000 0,22880644 0,23053111 ! transcription initiation GO:0006352 153 94 0,000 0,22880644 0,23043462 ! regulation of T cell activation GO:0050863 158 94 0,000 0,22880644 0,2303382 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,23093844 0,23238724 ! forebrain development GO:0030900 188 95 0,000 0,23093844 0,23229009 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,23093844 0,23219302 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,23306462 0,23423286 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,23306462 0,23413506 ! positive regulation of immune response GO:0050778 156 96 0,000 0,23306462 0,23403734 ! detection of stimulus GO:0051606 151 96 0,000 0,23306462 0,23393971 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,23518499 0,2359696 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,23518499 0,23587123 ! protein ubiquitination GO:0016567 217 97 0,000 0,23518499 0,23577295 ! hormone metabolic process GO:0042445 157 97 0,000 0,23518499 0,23567476 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,23729957 0,23769474 ! interphase GO:0051325 213 98 0,000 0,23729957 0,23759582 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,23729957 0,23749699 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,23940837 0,23950792 ! cell cycle arrest GO:0007050 213 100 0,000 0,24151141 0,24151141