pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/517-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 4,478E-10 1,077E-06 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 4,000 2,656E-08 3,195E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 8,937E-08 7,168E-05 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 2,838E-07 1,707E-04 ! carbohydrate homeostasis GO:0033500 53 38 4,000 8,052E-07 3,875E-04 GO:0042593|glucose homeostasis, ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 9,314E-07 3,735E-04 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 3,000 9,314E-07 3,201E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 1,823E-06 5,484E-04 ! nuclear migration GO:0007097 12 6 2,000 1,823E-06 4,874E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,823E-06 4,387E-04 GO:0031272|regulation of pseudopodium assembly, ! pancreas development GO:0031016 35 20 3,000 1,876E-06 4,104E-04 ! inner ear receptor cell differentiation GO:0060113 37 20 3,000 1,876E-06 3,762E-04 ! cell growth GO:0016049 84 45 4,000 1,91E-06 3,536E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 2,136E-06 3,67E-04 ! mechanoreceptor differentiation GO:0042490 40 22 3,000 2,813E-06 4,511E-04 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 3,18E-06 4,782E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 3,18E-06 4,501E-04 ! macrophage differentiation GO:0030225 11 7 2,000 3,18E-06 4,251E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 3,000 3,393E-06 4,296E-04 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 4,000 3,594E-06 4,323E-04 ! regulation of insulin secretion GO:0050796 37 25 3,000 4,813E-06 5,514E-04 ! interaction with host GO:0051701 62 25 3,000 4,813E-06 5,263E-04 ! forebrain development GO:0030900 188 95 5,000 4,948E-06 5,176E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 5,071E-06 5,084E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 5,071E-06 4,881E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 5,071E-06 4,693E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 5,668E-06 5,051E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 7,582E-06 6,515E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 8,086E-06 6,708E-04 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 8,776E-06 7,038E-04 ! regulation of peptide secretion GO:0002791 47 29 3,000 8,909E-06 6,915E-04 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 1,029E-05 7,739E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 1,112E-05 8,111E-04 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 1,479E-05 1,047E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 1,479E-05 1,017E-03 ! neuroblast proliferation GO:0007405 24 11 2,000 1,479E-05 9,887E-04 ! nucleus localization GO:0051647 19 11 2,000 1,479E-05 9,62E-04 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 3,000 1,709E-05 1,082E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 1,966E-05 1,213E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,966E-05 1,183E-03 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 1,966E-05 1,154E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 2,409E-05 1,38E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 2,547E-05 1,425E-03 ! protein oligomerization GO:0051259 139 78 4,000 2,927E-05 1,601E-03 ! activation of protein kinase activity GO:0032147 147 79 4,000 3,114E-05 1,665E-03 ! regulation of hormone secretion GO:0046883 62 40 3,000 3,298E-05 1,725E-03 ! response to hypoxia GO:0001666 171 81 4,000 3,514E-05 1,799E-03 ! response to oxygen levels GO:0070482 176 83 4,000 3,953E-05 1,982E-03 ! regulation of T cell mediated immunity GO:0002709 33 15 2,000 4,025E-05 1,977E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 4,025E-05 1,937E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 4,406E-05 2,079E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 4,938E-05 2,285E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 4,938E-05 2,242E-03 ! filopodium assembly GO:0046847 32 16 2,000 4,938E-05 2,2E-03 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 2,000 4,938E-05 2,16E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 5,765E-05 2,477E-03 ! myoblast differentiation GO:0045445 45 17 2,000 5,976E-05 2,523E-03 ! microspike assembly GO:0030035 36 17 2,000 5,976E-05 2,479E-03 ! leukocyte differentiation GO:0002521 202 96 4,000 7,938E-05 3,237E-03 ! inner ear development GO:0048839 79 50 3,000 8,023E-05 3,217E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 8,459E-05 3,337E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 8,459E-05 3,283E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 9,188E-05 3,509E-03 GO:0060538|skeletal muscle organ development, ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 9,919E-05 3,729E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of interleukin-2 production GO:0032663 35 20 2,000 9,919E-05 3,672E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 1,343E-04 4,894E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 1,526E-04 5,478E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 1,738E-04 6,149E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 1,738E-04 6,059E-03 ! regulation of protein complex assembly GO:0043254 117 61 3,000 1,749E-04 6,011E-03 ! ear development GO:0043583 103 62 3,000 1,863E-04 6,313E-03 ! regulation of blood coagulation GO:0030193 40 25 2,000 1,968E-04 6,577E-03 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 1,000 2,036E-04 6,71E-03 ! neuron fate determination GO:0048664 7 5 1,000 2,036E-04 6,619E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,036E-04 6,531E-03 ! anagen GO:0042640 6 5 1,000 2,036E-04 6,445E-03 ! microvillus organization GO:0032528 7 5 1,000 2,036E-04 6,361E-03 GO:0030033|microvillus assembly, ! muscle cell migration GO:0014812 8 5 1,000 2,036E-04 6,28E-03 ! regulation of response to food GO:0032095 7 5 1,000 2,036E-04 6,2E-03 ! response to food GO:0032094 6 5 1,000 2,036E-04 6,123E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,036E-04 6,047E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,036E-04 5,974E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,036E-04 5,902E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 2,036E-04 5,831E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 2,036E-04 5,763E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 2,036E-04 5,696E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! regulation of sterol transport GO:0032371 7 5 1,000 2,036E-04 5,63E-03 GO:0032374|regulation of cholesterol transport, ! regulation of cellular ketone metabolic process GO:0010565 44 26 2,000 2,217E-04 6,063E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 2,237E-04 6,048E-03 ! cell projection assembly GO:0030031 120 66 3,000 2,373E-04 6,345E-03 ! neuron fate commitment GO:0048663 48 27 2,000 2,486E-04 6,574E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 2,486E-04 6,502E-03 ! fat cell differentiation GO:0045444 50 27 2,000 2,486E-04 6,432E-03 ! negative regulation of neuron differentiation GO:0045665 42 27 2,000 2,486E-04 6,364E-03 ! lung development GO:0030324 144 67 3,000 2,515E-04 6,37E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 2,515E-04 6,304E-03 ! respiratory tube development GO:0030323 150 70 3,000 2,977E-04 7,385E-03 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 1,000 3,045E-04 7,475E-03 ! regulation of interferon-beta production GO:0032648 8 6 1,000 3,045E-04 7,4E-03 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! hyperosmotic response GO:0006972 9 6 1,000 3,045E-04 7,326E-03 ! regulation of appetite GO:0032098 9 6 1,000 3,045E-04 7,253E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,045E-04 7,182E-03 ! male sex determination GO:0030238 15 6 1,000 3,045E-04 7,112E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 3,045E-04 7,044E-03 GO:0045686|negative regulation of glial cell differentiation, ! interaction with symbiont GO:0051702 13 6 1,000 3,045E-04 6,977E-03 ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 3,045E-04 6,911E-03 ! response to exogenous dsRNA GO:0043330 10 6 1,000 3,045E-04 6,846E-03 ! hair follicle maturation GO:0048820 7 6 1,000 3,045E-04 6,783E-03 ! regulation of interleukin-13 production GO:0032656 11 6 1,000 3,045E-04 6,721E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 3,045E-04 6,66E-03 GO:0043011|myeloid dendritic cell differentiation, ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 3,045E-04 6,6E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 3,085E-04 6,628E-03 ! complement activation, classical pathway GO:0006958 48 29 2,000 3,085E-04 6,57E-03 ! regulation of coagulation GO:0050818 46 29 2,000 3,085E-04 6,512E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 3,000 3,144E-04 6,578E-03 ! respiratory system development GO:0060541 153 72 3,000 3,317E-04 6,88E-03 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 2,000 3,77E-04 7,754E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 4,147E-04 8,455E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 4,25E-04 8,593E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,25E-04 8,521E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,25E-04 8,451E-03 ! regulation of gluconeogenesis GO:0006111 7 7 1,000 4,25E-04 8,381E-03 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 4,25E-04 8,313E-03 ! vesicle fusion GO:0006906 17 7 1,000 4,25E-04 8,246E-03 ! response to dietary excess GO:0002021 8 7 1,000 4,25E-04 8,18E-03 ! fibrinolysis GO:0042730 10 7 1,000 4,25E-04 8,115E-03 ! eating behavior GO:0042755 7 7 1,000 4,25E-04 8,051E-03 ! regulation of interleukin-10 production GO:0032653 13 7 1,000 4,25E-04 7,988E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 4,25E-04 7,926E-03 ! regulation of lipid transport GO:0032368 14 7 1,000 4,25E-04 7,866E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 4,25E-04 7,805E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 4,25E-04 7,746E-03 ! negative regulation of osteoclast differentiation GO:0045671 10 7 1,000 4,25E-04 7,688E-03 ! lymph node development GO:0048535 10 7 1,000 4,25E-04 7,631E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 4,25E-04 7,574E-03 ! adult feeding behavior GO:0008343 9 7 1,000 4,25E-04 7,519E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 4,25E-04 7,464E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 4,25E-04 7,41E-03 ! cell fate specification GO:0001708 52 33 2,000 4,546E-04 7,869E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 4,727E-04 8,124E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 4,727E-04 8,066E-03 ! muscle cell differentiation GO:0042692 159 80 3,000 4,958E-04 8,401E-03 ! protein import into nucleus GO:0006606 158 80 3,000 4,958E-04 8,343E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 5,198E-04 8,685E-03 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 3,000 5,198E-04 8,625E-03 ! calcium-mediated signaling GO:0019722 62 35 2,000 5,417E-04 8,928E-03 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 5,445E-04 8,912E-03 ! regulation of interferon-alpha production GO:0032647 11 8 1,000 5,65E-04 9,184E-03 ! regulation of response to extracellular stimulus GO:0032104 13 8 1,000 5,65E-04 9,123E-03 GO:0032107|regulation of response to nutrient levels, ! hemoglobin metabolic process GO:0020027 13 8 1,000 5,65E-04 9,062E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 5,65E-04 9,002E-03 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 5,65E-04 8,943E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 5,65E-04 8,884E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,65E-04 8,827E-03 ! regulation of interleukin-4 production GO:0032673 17 8 1,000 5,65E-04 8,77E-03 ! regulation of Rac protein signal transduction GO:0035020 11 8 1,000 5,65E-04 8,713E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 1,000 5,65E-04 8,658E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 5,89E-04 8,97E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 6,389E-04 9,668E-03 ! protein localization in nucleus GO:0034504 176 87 3,000 6,809E-04 0,01023943 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 2,000 6,913E-04 0,01033158 GO:0006956|complement activation, ! regulation of developmental growth GO:0048638 15 9 1,000 7,242E-04 0,01075584 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 7,242E-04 0,01068985 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 7,242E-04 0,01062467 ! regulation of glycolysis GO:0006110 21 9 1,000 7,242E-04 0,01056028 ! regulation of type I interferon production GO:0032479 12 9 1,000 7,242E-04 0,01049666 ! retinol metabolic process GO:0042572 18 9 1,000 7,242E-04 0,01043381 ! protein heterooligomerization GO:0051291 16 9 1,000 7,242E-04 0,0103717 ! gas homeostasis GO:0033483 16 9 1,000 7,242E-04 0,01031033 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 7,242E-04 0,01024968 ! induction of an organ GO:0001759 14 9 1,000 7,242E-04 0,01018974 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 7,242E-04 0,0101305 GO:0002820|negative regulation of adaptive immune response, ! regulation of lymphocyte mediated immunity GO:0002706 74 39 2,000 7,465E-04 0,01038166 ! mesenchymal cell development GO:0014031 87 40 2,000 8,043E-04 0,01112194 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of T cell differentiation GO:0045580 70 41 2,000 8,65E-04 0,0118919 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 9,026E-04 0,01233843 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 9,026E-04 0,01226872 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 9,026E-04 0,0121998 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 1,000 9,026E-04 0,01213164 ! glucan biosynthetic process GO:0009250 14 10 1,000 9,026E-04 0,01206424 GO:0005978|glycogen biosynthetic process, ! regulation of gliogenesis GO:0014013 23 10 1,000 9,026E-04 0,01199759 GO:0045685|regulation of glial cell differentiation, ! response to dsRNA GO:0043331 20 10 1,000 9,026E-04 0,01193167 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 9,026E-04 0,01186647 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 9,026E-04 0,01180198 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 20 10 1,000 9,026E-04 0,01173818 ! localization within membrane GO:0051668 20 10 1,000 9,026E-04 0,01167507 ! regulation of T cell activation GO:0050863 158 94 3,000 9,103E-04 0,01171208 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 9,284E-04 0,01188161 GO:0090047|positive regulation of transcription regulator activity, ! regulation of leukocyte mediated immunity GO:0002703 79 42 2,000 9,284E-04 0,01181874 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 9,284E-04 0,01175654 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 9,47E-04 0,01192902 ! positive regulation of immune response GO:0050778 156 96 3,000 9,847E-04 0,01233959 ! receptor-mediated endocytosis GO:0006898 88 43 2,000 9,947E-04 0,01240063 ! energy reserve metabolic process GO:0006112 74 43 2,000 9,947E-04 0,01233671 ! interphase GO:0051325 213 98 3,000 1,063E-03 0,01311946 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 2,000 1,064E-03 0,01306092 ! JAK-STAT cascade GO:0007259 71 44 2,000 1,064E-03 0,01299462 ! neuron fate specification GO:0048665 17 11 1,000 1,1E-03 0,01336477 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 1,1E-03 0,01329761 GO:0046579|positive regulation of Ras protein signal transduction, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,1E-03 0,01323112 ! ventral spinal cord development GO:0021517 21 11 1,000 1,1E-03 0,01316529 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 1,1E-03 0,01310012 ! regulation of osteoclast differentiation GO:0045670 17 11 1,000 1,1E-03 0,01303558 ! positive regulation of JNK cascade GO:0046330 23 11 1,000 1,1E-03 0,01297168 ! developmental induction GO:0031128 19 11 1,000 1,1E-03 0,01290841 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 1,1E-03 0,01284575 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 2,000 1,136E-03 0,01320635 ! positive regulation of DNA binding GO:0043388 73 47 2,000 1,29E-03 0,0149192 ! regulation of adaptive immune response GO:0002819 84 47 2,000 1,29E-03 0,01484782 ! regulation of JNK cascade GO:0046328 94 47 2,000 1,29E-03 0,01477712 ! protein homooligomerization GO:0051260 76 47 2,000 1,29E-03 0,01470708 ! virus-host interaction GO:0019048 29 12 1,000 1,316E-03 0,014934 ! hippocampus development GO:0021766 26 12 1,000 1,316E-03 0,01486389 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,316E-03 0,01479443 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,316E-03 0,01472562 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 1,000 1,316E-03 0,01465745 ! entry into host cell GO:0030260 32 12 1,000 1,316E-03 0,0145899 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 1,000 1,316E-03 0,01452297 ! histone acetylation GO:0016573 26 12 1,000 1,316E-03 0,01445666 ! gland morphogenesis GO:0022612 29 12 1,000 1,316E-03 0,01439095 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,316E-03 0,01432583 ! T cell homeostasis GO:0043029 25 12 1,000 1,316E-03 0,0142613 ! regulation of steroid biosynthetic process GO:0050810 17 12 1,000 1,316E-03 0,01419735 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,371E-03 0,01472824 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 1,371E-03 0,01466278 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 1,371E-03 0,0145979 ! endocrine system development GO:0035270 104 49 2,000 1,456E-03 0,01543023 ! immunoglobulin mediated immune response GO:0016064 83 49 2,000 1,456E-03 0,01536256 GO:0019724|B cell mediated immunity, ! regulation of cell projection organization GO:0031344 121 50 2,000 1,544E-03 0,01621798 ! regulation of chemokine production GO:0032642 18 13 1,000 1,551E-03 0,01621958 ! lipid localization GO:0010876 28 13 1,000 1,551E-03 0,01614937 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 1,551E-03 0,01607976 ! endocrine pancreas development GO:0031018 22 13 1,000 1,551E-03 0,01601074 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 1,000 1,551E-03 0,01594232 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,551E-03 0,01587448 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,551E-03 0,01580722 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 1,551E-03 0,01574052 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 1,551E-03 0,01567438 ! positive regulation of binding GO:0051099 78 51 2,000 1,635E-03 0,01645603 ! chromatin remodeling GO:0006338 109 51 2,000 1,635E-03 0,01638747 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 1,635E-03 0,01631947 ! positive regulation of growth GO:0045927 90 52 2,000 1,729E-03 0,01719005 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,804E-03 0,01785719 ! response to UV GO:0009411 104 53 2,000 1,827E-03 0,01801238 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 2,032E-03 0,01995739 ! sulfate transport GO:0008272 23 15 1,000 2,075E-03 0,02029261 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 2,075E-03 0,02021045 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! pituitary gland development GO:0021983 29 15 1,000 2,075E-03 0,02012896 ! regulation of vasodilation GO:0042312 26 15 1,000 2,075E-03 0,02004812 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,075E-03 0,01996793 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 2,075E-03 0,01988837 ! cell killing GO:0001906 29 15 1,000 2,075E-03 0,01980945 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,075E-03 0,01973115 ! skeletal muscle fiber development GO:0048741 111 56 2,000 2,14E-03 0,02027271 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 2,252E-03 0,02124468 ! muscle fiber development GO:0048747 112 57 2,000 2,252E-03 0,02116169 ! auditory receptor cell differentiation GO:0042491 32 16 1,000 2,364E-03 0,02213288 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 2,364E-03 0,02204709 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 1,000 2,364E-03 0,02196197 ! complement activation, alternative pathway GO:0006957 18 16 1,000 2,364E-03 0,0218775 ! response to osmotic stress GO:0006970 25 16 1,000 2,364E-03 0,02179368 ! negative regulation of immune response GO:0050777 35 16 1,000 2,364E-03 0,02171049 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,364E-03 0,02162794 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 2,364E-03 0,02154602 ! positive regulation of secretion GO:0051047 95 59 2,000 2,485E-03 0,02256327 ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 2,485E-03 0,02247845 ! establishment of organelle localization GO:0051656 109 59 2,000 2,485E-03 0,02239426 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 2,607E-03 0,02340746 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 2,671E-03 0,02389367 ! limbic system development GO:0021761 36 17 1,000 2,671E-03 0,02380518 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 2,671E-03 0,02371734 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,671E-03 0,02363014 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 2,671E-03 0,02354358 ! viral reproductive process GO:0022415 126 62 2,000 2,863E-03 0,02513681 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,996E-03 0,02621096 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 2,996E-03 0,02612075 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,996E-03 0,02602645 ! positive regulation of proteolysis GO:0045862 31 18 1,000 2,996E-03 0,02593283 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,996E-03 0,02583988 ! regulation of steroid metabolic process GO:0019218 30 18 1,000 2,996E-03 0,0257476 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,996E-03 0,02565597 ! lymphocyte mediated immunity GO:0002449 114 64 2,000 3,133E-03 0,02672899 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 3,274E-03 0,02783127 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 3,339E-03 0,02828711 ! lipid phosphorylation GO:0046834 35 19 1,000 3,339E-03 0,02818786 ! bile acid metabolic process GO:0008206 29 19 1,000 3,339E-03 0,0280893 ! actin filament bundle formation GO:0051017 42 19 1,000 3,339E-03 0,02799143 ! response to lipopolysaccharide GO:0032496 30 19 1,000 3,339E-03 0,02789423 ! peptide cross-linking GO:0018149 37 19 1,000 3,339E-03 0,02779771 ! visual learning GO:0008542 36 19 1,000 3,339E-03 0,02770186 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 3,339E-03 0,02760666 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 3,339E-03 0,02751212 ! proximal/distal pattern formation GO:0009954 32 19 1,000 3,339E-03 0,02741822 ! developmental maturation GO:0021700 116 66 2,000 3,418E-03 0,02797319 ! regulation of cellular response to stress GO:0080135 128 67 2,000 3,567E-03 0,02908901 ! homeostasis of number of cells GO:0048872 114 67 2,000 3,567E-03 0,02899073 ! positive regulation of T cell activation GO:0050870 109 67 2,000 3,567E-03 0,02889312 ! adaptive immune response GO:0002250 119 67 2,000 3,567E-03 0,02879617 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 2,000 3,567E-03 0,02869986 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,699E-03 0,02966546 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,699E-03 0,0295669 ! retinoid metabolic process GO:0001523 32 20 1,000 3,699E-03 0,029469 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 3,699E-03 0,02937174 ! cellular response to starvation GO:0009267 33 20 1,000 3,699E-03 0,02927512 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 3,699E-03 0,02917914 ! diencephalon development GO:0021536 34 20 1,000 3,699E-03 0,02908378 ! peptidyl-serine modification GO:0018209 43 20 1,000 3,699E-03 0,02898905 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 1,000 3,699E-03 0,02889493 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 3,699E-03 0,02880142 ! negative regulation of coagulation GO:0050819 29 20 1,000 3,699E-03 0,02870851 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 3,719E-03 0,02877088 ! viral reproduction GO:0016032 134 68 2,000 3,719E-03 0,02867867 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 3,719E-03 0,02858704 ! regulation of cell killing GO:0031341 42 21 1,000 4,076E-03 0,03123322 ! inactivation of MAPK activity GO:0000188 39 21 1,000 4,076E-03 0,03113407 ! cell aging GO:0007569 44 21 1,000 4,076E-03 0,03103554 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 4,076E-03 0,03093764 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 4,076E-03 0,03084035 ! cytolysis GO:0019835 24 21 1,000 4,076E-03 0,03074367 ! regulation of vasoconstriction GO:0019229 39 21 1,000 4,076E-03 0,0306476 ! detection of biotic stimulus GO:0009595 29 21 1,000 4,076E-03 0,03055212 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 4,076E-03 0,03045724 ! vitamin A metabolic process GO:0006776 33 21 1,000 4,076E-03 0,03036295 ! terpenoid metabolic process GO:0006721 37 21 1,000 4,076E-03 0,03026923 ! humoral immune response GO:0006959 109 71 2,000 4,2E-03 0,03108931 ! regulation of immune effector process GO:0002697 137 71 2,000 4,2E-03 0,03099394 ! acute inflammatory response GO:0002526 113 72 2,000 4,368E-03 0,03213649 ! regulation of caspase activity GO:0043281 122 72 2,000 4,368E-03 0,03203851 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 4,368E-03 0,03194113 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 4,47E-03 0,03259373 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 4,47E-03 0,03249526 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,47E-03 0,03239738 ! central nervous system neuron development GO:0021954 46 22 1,000 4,47E-03 0,03230009 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 4,47E-03 0,03220338 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 4,47E-03 0,03210725 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 4,47E-03 0,0320117 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 4,47E-03 0,03191671 ! protein stabilization GO:0050821 39 22 1,000 4,47E-03 0,03182228 ! regulation of transcription factor activity GO:0051090 126 74 2,000 4,716E-03 0,03347204 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 2,000 4,716E-03 0,03337359 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 4,716E-03 0,03327572 ! organelle localization GO:0051640 136 74 2,000 4,716E-03 0,03317842 ! positive regulation of DNA replication GO:0045740 43 23 1,000 4,882E-03 0,03424299 ! visual behavior GO:0007632 42 23 1,000 4,882E-03 0,03414345 ! regulation of DNA recombination GO:0000018 48 23 1,000 4,882E-03 0,03404448 ! sex determination GO:0007530 47 23 1,000 4,882E-03 0,03394609 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 4,882E-03 0,03384826 ! regulation of catabolic process GO:0009894 161 76 2,000 5,081E-03 0,0351286 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 5,27E-03 0,03632816 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 5,31E-03 0,03650027 ! regulation of transmembrane transport GO:0034762 38 24 1,000 5,31E-03 0,03639629 ! vesicle docking GO:0048278 47 24 1,000 5,31E-03 0,03629289 ! spinal cord development GO:0021510 47 24 1,000 5,31E-03 0,03619007 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 5,31E-03 0,03608784 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 5,31E-03 0,03598619 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 5,31E-03 0,0358851 GO:0002708|positive regulation of lymphocyte mediated immunity, ! membrane depolarization GO:0051899 39 24 1,000 5,31E-03 0,03578458 ! pallium development GO:0021543 49 24 1,000 5,31E-03 0,03568463 ! leukocyte homeostasis GO:0001776 44 24 1,000 5,31E-03 0,03558523 ! protein tetramerization GO:0051262 52 24 1,000 5,31E-03 0,03548638 ! blood coagulation GO:0007596 146 78 2,000 5,462E-03 0,03640534 GO:0050817|coagulation, ! vasculogenesis GO:0001570 46 25 1,000 5,754E-03 0,0382453 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 5,754E-03 0,03813994 ! response to starvation GO:0042594 42 25 1,000 5,754E-03 0,03803516 ! negative regulation of cell development GO:0010721 73 25 1,000 5,754E-03 0,03793095 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 5,754E-03 0,03782731 ! cellular response to nutrient levels GO:0031669 41 25 1,000 5,754E-03 0,03772424 ! liver development GO:0001889 53 25 1,000 5,754E-03 0,03762173 ! T cell activation GO:0042110 168 81 2,000 6,066E-03 0,03955136 ! regulation of neuron differentiation GO:0045664 167 81 2,000 6,066E-03 0,03944446 ! initiation of viral infection GO:0019059 57 26 1,000 6,215E-03 0,04030747 ! regulation of interferon-gamma production GO:0032649 39 26 1,000 6,215E-03 0,04019911 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 6,215E-03 0,04009134 ! molting cycle process GO:0022404 50 26 1,000 6,215E-03 0,03998415 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 6,215E-03 0,03987752 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 6,215E-03 0,03977146 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 6,215E-03 0,03966597 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 6,215E-03 0,03956103 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 6,693E-03 0,04248691 ! spliceosomal snRNP biogenesis GO:0000387 36 27 1,000 6,693E-03 0,0423751 ! protein amino acid acylation GO:0043543 55 27 1,000 6,693E-03 0,04226388 ! fat-soluble vitamin metabolic process GO:0006775 40 27 1,000 6,693E-03 0,04215324 ! hemostasis GO:0007599 158 84 2,000 6,708E-03 0,04213792 ! positive regulation of cell activation GO:0050867 145 85 2,000 6,93E-03 0,04342282 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 7,186E-03 0,04490864 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 7,186E-03 0,0447923 ! positive regulation of protein modification process GO:0031401 136 88 2,000 7,624E-03 0,0474003 ! regulation of DNA binding GO:0051101 155 88 2,000 7,624E-03 0,04727813 ! gland development GO:0048732 206 88 2,000 7,624E-03 0,0471566 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 7,696E-03 0,04747581 ! cell fate determination GO:0001709 60 29 1,000 7,696E-03 0,04735439 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 7,696E-03 0,04723359 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 7,696E-03 0,0471134 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 7,696E-03 0,04699382 ! membrane docking GO:0022406 61 30 1,000 8,221E-03 0,05007439 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 8,221E-03 0,04994794 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 8,221E-03 0,04982213 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 8,221E-03 0,04969695 ! response to heat GO:0009408 50 30 1,000 8,221E-03 0,04957239 ! vitamin metabolic process GO:0006766 139 92 2,000 8,611E-03 0,05179637 ! cholesterol homeostasis GO:0042632 53 31 1,000 8,762E-03 0,05257087 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 8,762E-03 0,05244009 ! triglyceride metabolic process GO:0006641 43 31 1,000 8,762E-03 0,05230997 ! myeloid leukocyte activation GO:0002274 49 31 1,000 8,762E-03 0,05218049 ! positive regulation of immune effector process GO:0002699 67 31 1,000 8,762E-03 0,05205165 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 8,869E-03 0,05255917 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 8,869E-03 0,05243004 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 9,318E-03 0,05495049 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 9,318E-03 0,05481614 ! cholesterol transport GO:0030301 56 32 1,000 9,318E-03 0,05468244 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 9,318E-03 0,05454939 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 9,318E-03 0,05441699 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 9,318E-03 0,05428523 ! sterol transport GO:0015918 57 33 1,000 9,89E-03 0,05747746 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 9,946E-03 0,05766112 ! hormone metabolic process GO:0042445 157 97 2,000 9,946E-03 0,05752251 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01047721 0,06045125 ! placenta development GO:0001890 53 34 1,000 0,01047721 0,06030662 ! cell cycle arrest GO:0007050 213 100 2,000 0,0108009 0,06202142 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01107936 0,06346891 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,01107936 0,06331815 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 1,000 0,01107936 0,06316811 ! cytokine production GO:0001816 59 35 1,000 0,01107936 0,06301877 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01107936 0,06287014 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01169644 0,0662156 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01169644 0,06606016 ! actomyosin structure organization GO:0031032 62 37 1,000 0,0123283 0,06946577 ! tissue remodeling GO:0048771 76 37 1,000 0,0123283 0,06930347 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,0123283 0,06914192 ! regulation of protein stability GO:0031647 73 37 1,000 0,0123283 0,06898113 ! glycogen metabolic process GO:0005977 61 37 1,000 0,0123283 0,06882108 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,0129748 0,0722624 ! lipid homeostasis GO:0055088 67 38 1,000 0,0129748 0,07209551 ! isoprenoid metabolic process GO:0006720 66 38 1,000 0,0129748 0,0719294 ! glucan metabolic process GO:0044042 62 38 1,000 0,0129748 0,07176404 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01363579 0,07524702 ! learning GO:0007612 77 39 1,000 0,01363579 0,07507483 ! segmentation GO:0035282 67 39 1,000 0,01363579 0,07490342 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,01363579 0,0747328 ! organic ether metabolic process GO:0018904 55 39 1,000 0,01363579 0,07456295 ! feeding behavior GO:0007631 59 40 1,000 0,01431113 0,07807838 ! cytokinesis GO:0000910 72 40 1,000 0,01431113 0,07790174 ! T cell differentiation GO:0030217 81 41 1,000 0,01500067 0,08147092 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01500067 0,08128743 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01570429 0,08490901 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01642182 0,08858949 ! glucose transport GO:0015758 65 43 1,000 0,01642182 0,0883913 ! hexose transport GO:0008645 67 44 1,000 0,01715315 0,09212161 GO:0015749|monosaccharide transport, ! developmental growth GO:0048589 82 44 1,000 0,01715315 0,09191644 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01789812 0,09569531 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,01789812 0,09548312 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01865661 0,0993093 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01865661 0,09909007 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01865661 0,09887181 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01865661 0,09865451 ! activation of caspase activity GO:0006919 84 48 1,000 0,02021357 0,10665317 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02101177 0,11062214 ! neuromuscular process GO:0050905 99 50 1,000 0,02182294 0,11464193 ! histone modification GO:0016570 91 50 1,000 0,02182294 0,11439216 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,02182294 0,11414348 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,02182294 0,11389588 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02254012 0,11738428 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02254012 0,11713075 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02254012 0,11687832 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02254012 0,11662697 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02254012 0,11637669 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02254012 0,11612749 ! polyol transport GO:0015791 12 5 0,000 0,02254012 0,11587936 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02254012 0,11563228 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02254012 0,11538625 ! response to superoxide GO:0000303 10 5 0,000 0,02254012 0,11514127 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02254012 0,11489733 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02254012 0,11465442 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02254012 0,11441253 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02254012 0,11417166 ! female meiosis GO:0007143 7 5 0,000 0,02254012 0,11393181 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02254012 0,11369295 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02254012 0,1134551 ! cobalt ion transport GO:0006824 11 5 0,000 0,02254012 0,11321825 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02254012 0,11298237 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02254012 0,11274748 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02254012 0,11251357 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02254012 0,11228062 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02254012 0,11204864 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02254012 0,11181761 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02254012 0,11158753 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02254012 0,1113584 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02254012 0,1111302 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02254012 0,11090294 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02254012 0,11067661 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02254012 0,1104512 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02254012 0,11022671 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02254012 0,11000312 ! negative chemotaxis GO:0050919 14 5 0,000 0,02254012 0,10978044 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02254012 0,10955867 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02254012 0,10933778 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02254012 0,10911779 ! behavioral response to pain GO:0048266 9 5 0,000 0,02254012 0,10889867 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02254012 0,10868044 ! Notch receptor processing GO:0007220 8 5 0,000 0,02254012 0,10846308 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02254012 0,10824659 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02254012 0,10803095 ! micturition GO:0060073 9 5 0,000 0,02254012 0,10781618 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02254012 0,10760226 ! copulation GO:0007620 9 5 0,000 0,02254012 0,10738919 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02254012 0,10717696 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02254012 0,10696556 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02254012 0,106755 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02254012 0,10654526 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02254012 0,10633635 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02254012 0,10612826 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02254012 0,10592098 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02254012 0,1057145 ! grooming behavior GO:0007625 6 5 0,000 0,02254012 0,10550883 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02254012 0,10530396 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02254012 0,10509988 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02254012 0,10489659 ! response to protozoan GO:0001562 10 5 0,000 0,02254012 0,10469409 ! lymph vessel development GO:0001945 10 5 0,000 0,02254012 0,10449237 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02254012 0,10429142 ! endochondral ossification GO:0001958 16 5 0,000 0,02254012 0,10409125 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02254012 0,10389184 ! parathyroid gland development GO:0060017 13 5 0,000 0,02254012 0,10369319 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02254012 0,1034953 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02254012 0,10329817 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02254012 0,10310179 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02254012 0,10290615 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02254012 0,10271125 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02254012 0,10251709 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02254012 0,10232366 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02254012 0,10213096 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02254012 0,10193898 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02254012 0,10174773 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02254012 0,10155719 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02254012 0,10136736 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02254012 0,10117825 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02254012 0,10098983 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02254012 0,10080212 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02254012 0,1006151 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02254012 0,10042878 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02254012 0,10024314 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02254012 0,10005819 ! histidine catabolic process GO:0006548 6 5 0,000 0,02254012 0,09987392 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02254012 0,09969033 ! valine metabolic process GO:0006573 10 5 0,000 0,02254012 0,09950741 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02254012 0,09932516 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02254012 0,09914358 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02254012 0,09896266 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02254012 0,0987824 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02254012 0,0986028 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02254012 0,09842385 ! polyol catabolic process GO:0046174 7 5 0,000 0,02254012 0,09824554 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02254012 0,09806788 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02254012 0,09789087 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02254012 0,09771449 ! mitochondrial fission GO:0000266 8 5 0,000 0,02254012 0,09753874 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02254012 0,09736363 ! mRNA transcription GO:0009299 9 5 0,000 0,02254012 0,09718914 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02254012 0,09701528 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02254012 0,09684203 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02254012 0,09666941 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02254012 0,0964974 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02254012 0,096326 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02254012 0,09615521 GO:0060177|regulation of angiotensin metabolic process, ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02254012 0,09598503 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02254012 0,09581544 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02254012 0,09564645 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02254012 0,09547806 ! forebrain neuron development GO:0021884 13 5 0,000 0,02254012 0,09531026 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02254012 0,09514305 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02254012 0,09497643 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02254012 0,09481038 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02254012 0,09464492 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02254012 0,09448003 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02254012 0,09431572 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02254012 0,09415198 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02254012 0,0939888 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02254012 0,09382619 ! basic amino acid transport GO:0015802 11 5 0,000 0,02254012 0,09366414 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02254012 0,09350265 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02254012 0,09334172 ! depyrimidination GO:0045008 10 5 0,000 0,02254012 0,09318134 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02254012 0,09302151 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02254012 0,09286223 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02254012 0,09270349 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02254012 0,09254529 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02254012 0,09238763 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02254012 0,09223051 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02254012 0,09207392 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02254012 0,09191786 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02254012 0,09176233 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02254012 0,09160733 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02254012 0,09145285 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02254012 0,09129889 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02254012 0,09114544 ! response to arsenic GO:0046685 10 5 0,000 0,02254012 0,09099252 ! mast cell degranulation GO:0043303 7 5 0,000 0,02254012 0,0908401 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02254012 0,09068819 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02254012 0,09053679 ! response to cadmium ion GO:0046686 7 5 0,000 0,02254012 0,0903859 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02254012 0,09023551 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02254012 0,09008561 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02254012 0,08993622 ! decidualization GO:0046697 11 5 0,000 0,02254012 0,08978732 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02254012 0,08963891 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02254012 0,08949099 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02254012 0,08934356 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02254012 0,08919661 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02254012 0,08905015 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02254012 0,08890416 ! neural tube patterning GO:0021532 7 5 0,000 0,02254012 0,08875866 ! embryonic cleavage GO:0040016 6 5 0,000 0,02254012 0,08861363 ! peroxisome fission GO:0016559 5 5 0,000 0,02254012 0,08846907 ! histone demethylation GO:0016577 10 5 0,000 0,02254012 0,08832498 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02254012 0,08818136 ! mitotic recombination GO:0006312 9 5 0,000 0,02254012 0,08803821 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02254012 0,08789553 ! metaphase plate congression GO:0051310 7 5 0,000 0,02254012 0,0877533 ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02254012 0,08761153 ! enteric nervous system development GO:0048484 8 5 0,000 0,02254012 0,08747022 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02254012 0,08732937 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02254012 0,08718897 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02254012 0,08704902 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02254012 0,08690952 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02254012 0,08677046 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02254012 0,08663185 ! plasminogen activation GO:0031639 5 5 0,000 0,02254012 0,08649368 ! B cell homeostasis GO:0001782 13 5 0,000 0,02254012 0,08635595 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02254012 0,08621866 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02254012 0,08608181 ! metaphase GO:0051323 8 5 0,000 0,02254012 0,08594539 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02254012 0,0858094 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02254012 0,08567384 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02254012 0,08553871 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02254012 0,085404 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02254012 0,08526972 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02254012 0,08513585 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02254012 0,08500241 ! response to redox state GO:0051775 5 5 0,000 0,02254012 0,08486939 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02254012 0,08473678 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02254012 0,08460459 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02254012 0,0844728 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02254012 0,08434143 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02254012 0,08421046 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02254012 0,08407991 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02254012 0,08394975 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02254012 0,08382 ! striatum development GO:0021756 9 5 0,000 0,02254012 0,08369065 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02254012 0,08356169 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02254012 0,08343314 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02254012 0,08330498 ! glial cell migration GO:0008347 11 5 0,000 0,02254012 0,08317721 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02254012 0,08304983 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02254012 0,08292284 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02254012 0,08279624 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02254012 0,08267003 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02254012 0,0825442 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02254012 0,08241875 ! neuroprotection GO:0043526 6 5 0,000 0,02254012 0,08229369 ! neural plate development GO:0001840 8 5 0,000 0,02254012 0,082169 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02254012 0,08204469 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02254012 0,08192075 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02254012 0,08179719 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02254012 0,08167401 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02254012 0,08155119 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02254012 0,08142874 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02254012 0,08130666 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02254012 0,08118494 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02254012 0,08106359 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02254012 0,0809426 ! spindle assembly GO:0051225 6 5 0,000 0,02254012 0,08082197 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02254012 0,0807017 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02254012 0,08058178 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02254012 0,08046222 ! drug metabolic process GO:0017144 6 5 0,000 0,02254012 0,08034302 ! stem cell division GO:0017145 11 5 0,000 0,02254012 0,08022417 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02254012 0,08010567 ! organ regeneration GO:0031100 7 5 0,000 0,02254012 0,07998752 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02254012 0,07986972 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02254012 0,07975226 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02254012 0,07963515 ! viral infectious cycle GO:0019058 99 51 1,000 0,02264696 0,07989527 ! excretion GO:0007588 83 51 1,000 0,02264696 0,07977829 ! vesicle organization GO:0016050 107 51 1,000 0,02264696 0,07966166 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,02348367 0,08248426 ! membrane fusion GO:0006944 110 52 1,000 0,02348367 0,08236402 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02348367 0,08224413 ! cell maturation GO:0048469 100 53 1,000 0,02433297 0,08509465 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02433297 0,08497114 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,02433297 0,084848 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02519471 0,0877257 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,02606876 0,09063792 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02606876 0,09050713 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02606876 0,09037671 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,02606876 0,09024668 ! aging GO:0007568 103 55 1,000 0,02606876 0,09011701 ! heart morphogenesis GO:0003007 97 55 1,000 0,02606876 0,08998772 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,02606876 0,0898588 ! regulation of DNA replication GO:0006275 101 56 1,000 0,026955 0,09278075 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,026955 0,0926482 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02698726 0,09262673 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02698726 0,09249478 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02698726 0,09236321 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02698726 0,09223201 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02698726 0,09210119 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02698726 0,09197073 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02698726 0,09184065 ! sleep GO:0030431 13 6 0,000 0,02698726 0,09171093 ! response to oxygen radical GO:0000305 11 6 0,000 0,02698726 0,09158157 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02698726 0,09145259 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02698726 0,09132396 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02698726 0,0911957 ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02698726 0,09106779 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02698726 0,09094025 ! forebrain regionalization GO:0021871 8 6 0,000 0,02698726 0,09081306 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02698726 0,09068622 ! male meiosis GO:0007140 7 6 0,000 0,02698726 0,09055974 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02698726 0,09043362 ! response to zinc ion GO:0010043 9 6 0,000 0,02698726 0,09030784 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02698726 0,09018241 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02698726 0,09005733 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02698726 0,0899326 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02698726 0,08980821 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02698726 0,08968417 ! malate metabolic process GO:0006108 11 6 0,000 0,02698726 0,08956046 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02698726 0,0894371 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02698726 0,08931408 ! protein refolding GO:0042026 15 6 0,000 0,02698726 0,0891914 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02698726 0,08906905 ! opsonization GO:0008228 8 6 0,000 0,02698726 0,08894704 ! mating behavior GO:0007617 7 6 0,000 0,02698726 0,08882536 ! neuron remodeling GO:0016322 15 6 0,000 0,02698726 0,08870401 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02698726 0,088583 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02698726 0,08846231 ! equilibrioception GO:0050957 14 6 0,000 0,02698726 0,08834195 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02698726 0,08822192 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02698726 0,08810222 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02698726 0,08798284 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02698726 0,08786378 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02698726 0,08774505 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02698726 0,08762663 ! toxin metabolic process GO:0009404 11 6 0,000 0,02698726 0,08750854 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02698726 0,08739076 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02698726 0,0872733 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02698726 0,08715616 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02698726 0,08703932 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02698726 0,08692281 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02698726 0,0868066 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02698726 0,0866907 ! thymic T cell selection GO:0045061 12 6 0,000 0,02698726 0,08657511 ! protein lipoylation GO:0009249 10 6 0,000 0,02698726 0,08645984 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02698726 0,08634486 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02698726 0,08623019 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02698726 0,08611583 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02698726 0,08600177 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02698726 0,08588801 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02698726 0,08577455 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02698726 0,08566139 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02698726 0,08554853 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02698726 0,08543597 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02698726 0,0853237 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02698726 0,08521173 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02698726 0,08510005 ! urea metabolic process GO:0019627 7 6 0,000 0,02698726 0,08498866 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02698726 0,08487756 ! neutrophil activation GO:0042119 8 6 0,000 0,02698726 0,08476676 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02698726 0,08465624 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02698726 0,08454601 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02698726 0,08443607 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02698726 0,08432641 ! neuron apoptosis GO:0051402 9 6 0,000 0,02698726 0,08421704 ! nucleoside salvage GO:0043174 9 6 0,000 0,02698726 0,08410795 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02698726 0,08399914 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02698726 0,08389062 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02698726 0,08378237 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02698726 0,0836744 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02698726 0,08356671 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02698726 0,0834593 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02698726 0,08335216 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02698726 0,0832453 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02698726 0,08313871 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02698726 0,0830324 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02698726 0,08292636 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02698726 0,08282058 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02698726 0,08271508 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02698726 0,08260984 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02698726 0,08250487 ! monocyte differentiation GO:0030224 12 6 0,000 0,02698726 0,08240017 ! neural nucleus development GO:0048857 14 6 0,000 0,02698726 0,08229574 ! response to UV-C GO:0010225 11 6 0,000 0,02698726 0,08219156 ! astrocyte development GO:0014002 15 6 0,000 0,02698726 0,08208766 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02698726 0,08198401 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02698726 0,08188063 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02698726 0,0817775 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02698726 0,08167464 ! response to copper ion GO:0046688 10 6 0,000 0,02698726 0,08157203 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02698726 0,08146968 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02698726 0,08136759 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02698726 0,08126575 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02698726 0,08116417 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02698726 0,08106284 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02698726 0,08096177 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02698726 0,08086094 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02698726 0,08076037 ! Schwann cell development GO:0014044 15 6 0,000 0,02698726 0,08066004 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02698726 0,08055997 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02698726 0,08046014 ! subpallium development GO:0021544 10 6 0,000 0,02698726 0,08036056 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02698726 0,08026123 ! histone ubiquitination GO:0016574 8 6 0,000 0,02698726 0,08016214 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02698726 0,0800633 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02698726 0,0799647 ! G2 phase GO:0051319 16 6 0,000 0,02698726 0,07986634 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02698726 0,07976823 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02698726 0,07967035 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02698726 0,07957272 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02698726 0,07947532 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02698726 0,07937816 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02698726 0,07928124 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02698726 0,07918456 ! receptor internalization GO:0031623 10 6 0,000 0,02698726 0,07908811 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02698726 0,07899189 ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02698726 0,07889591 ! protein deubiquitination GO:0016579 14 6 0,000 0,02698726 0,07880017 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02698726 0,07870465 ! protein destabilization GO:0031648 9 6 0,000 0,02698726 0,07860937 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02698726 0,07851431 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02698726 0,07841949 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02698726 0,07832489 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02698726 0,07823053 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02698726 0,07813639 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02698726 0,07804247 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02698726 0,07794878 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02698726 0,07785532 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02698726 0,07776208 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02698726 0,07766906 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02698726 0,07757627 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02698726 0,07748369 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02698726 0,07739134 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02698726 0,07729921 ! catecholamine transport GO:0051937 9 6 0,000 0,02698726 0,0772073 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02698726 0,0771156 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02698726 0,07702412 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02698726 0,07693286 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02698726 0,07684182 ! maternal placenta development GO:0001893 12 6 0,000 0,02698726 0,07675099 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02698726 0,07666037 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02698726 0,07656997 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02698726 0,07647978 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02698726 0,07638981 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02698726 0,07630004 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02698726 0,07621049 ! lipid modification GO:0030258 97 57 1,000 0,02785331 0,07856397 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02785331 0,07847197 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02785331 0,07838019 ! regulation of endocytosis GO:0030100 91 58 1,000 0,02876355 0,08084708 ! adult behavior GO:0030534 99 58 1,000 0,02876355 0,08075274 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02876355 0,08065863 ! tRNA transcription GO:0009304 14 7 0,000 0,0314143 0,0879893 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0314143 0,08788698 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0314143 0,08778491 ! regulation of helicase activity GO:0051095 15 7 0,000 0,0314143 0,08768307 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0314143 0,08758147 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0314143 0,0874801 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0314143 0,08737897 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0314143 0,08727807 ! prostate gland development GO:0030850 13 7 0,000 0,0314143 0,0871774 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0314143 0,08707697 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0314143 0,08697676 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0314143 0,08687679 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0314143 0,08677704 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0314143 0,08667753 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0314143 0,08657824 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0314143 0,08647918 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0314143 0,08638035 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0314143 0,08628174 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0314143 0,08618336 ! glycolipid transport GO:0046836 10 7 0,000 0,0314143 0,0860852 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0314143 0,08598726 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0314143 0,08588955 ! neuron adhesion GO:0007158 12 7 0,000 0,0314143 0,08579206 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0314143 0,08569479 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0314143 0,08559774 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0314143 0,08550091 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0314143 0,0854043 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0314143 0,08530791 ! mRNA stabilization GO:0048255 18 7 0,000 0,0314143 0,08521173 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,0314143 0,08511577 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0314143 0,08502003 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0314143 0,0849245 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0314143 0,08482919 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0314143 0,08473409 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0314143 0,0846392 ! lipoprotein transport GO:0042953 14 7 0,000 0,0314143 0,08454453 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0314143 0,08445006 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0314143 0,08435581 ! rhythmic behavior GO:0007622 15 7 0,000 0,0314143 0,08426177 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0314143 0,08416794 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0314143 0,08407431 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0314143 0,0839809 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0314143 0,08388769 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0314143 0,08379469 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0314143 0,08370189 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0314143 0,0836093 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0314143 0,08351691 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0314143 0,08342473 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0314143 0,08333275 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0314143 0,08324098 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0314143 0,0831494 ! spinal cord patterning GO:0021511 13 7 0,000 0,0314143 0,08305803 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0314143 0,08296686 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0314143 0,08287588 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0314143 0,08278511 ! adrenal gland development GO:0030325 17 7 0,000 0,0314143 0,08269454 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0314143 0,08260416 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0314143 0,08251398 ! ovulation GO:0030728 9 7 0,000 0,0314143 0,082424 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0314143 0,08233421 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0314143 0,08224462 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0314143 0,08215522 ! microtubule nucleation GO:0007020 20 7 0,000 0,0314143 0,08206602 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0314143 0,08197701 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0314143 0,0818882 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0314143 0,08179957 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0314143 0,08171114 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0314143 0,0816229 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0314143 0,08153485 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0314143 0,08144699 ! galactose metabolic process GO:0006012 13 7 0,000 0,0314143 0,08135932 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0314143 0,08127183 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0314143 0,08118454 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0314143 0,08109743 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0314143 0,08101051 ! organ growth GO:0035265 15 7 0,000 0,0314143 0,08092378 ! purine salvage GO:0043101 10 7 0,000 0,0314143 0,08083723 ! nucleoside transport GO:0015858 8 7 0,000 0,0314143 0,08075086 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0314143 0,08066468 ! parturition GO:0007567 14 7 0,000 0,0314143 0,08057868 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0314143 0,08049287 ! rRNA modification GO:0000154 14 7 0,000 0,0314143 0,08040724 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0314143 0,08032179 ! spindle checkpoint GO:0031577 15 7 0,000 0,0314143 0,08023652 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0314143 0,08015144 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0314143 0,08006653 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0314143 0,07998181 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0314143 0,07989726 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0314143 0,07981289 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0314143 0,0797287 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,0314143 0,07964468 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0314143 0,07956085 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0314143 0,07947719 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0314143 0,0793937 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0314143 0,07931039 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0314143 0,07922726 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0314143 0,0791443 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0314143 0,07906151 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0314143 0,0789789 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0314143 0,07889646 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0314143 0,07881419 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0314143 0,07873209 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0314143 0,07865016 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0314143 0,07856841 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0314143 0,07848682 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0314143 0,0784054 ! regulation of meiosis GO:0040020 12 7 0,000 0,0314143 0,07832415 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0314143 0,07824307 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0314143 0,07816216 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0314143 0,07808141 GO:0002714|positive regulation of B cell mediated immunity, ! oxygen homeostasis GO:0032364 12 7 0,000 0,0314143 0,07800083 ! transcription termination GO:0006353 13 7 0,000 0,0314143 0,07792042 ! response to tumor cell GO:0002347 13 7 0,000 0,0314143 0,07784017 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0314143 0,07776009 ! anaphase GO:0051322 17 7 0,000 0,0314143 0,07768017 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0314143 0,07760042 ! axonal fasciculation GO:0007413 18 7 0,000 0,0314143 0,07752083 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0314143 0,0774414 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0314143 0,07736214 ! diuresis GO:0030146 12 7 0,000 0,0314143 0,07728303 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0314143 0,07720409 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0314143 0,07712531 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0314143 0,07704669 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0314143 0,07696823 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0314143 0,07688993 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0314143 0,07681179 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0314143 0,07673381 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0314143 0,07665599 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0314143 0,07657832 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0314143 0,07650082 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0314143 0,07642346 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0314143 0,07634627 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0314143 0,07626923 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0314143 0,07619234 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0314143 0,07611562 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0314143 0,07603904 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0314143 0,07596262 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0314143 0,07588635 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0314143 0,07581024 ! muscle adaptation GO:0043500 14 7 0,000 0,0314143 0,07573427 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0314143 0,07565846 ! retina homeostasis GO:0001895 12 7 0,000 0,0314143 0,07558281 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0314143 0,0755073 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0314143 0,07543194 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0314143 0,07535674 ! protein prenylation GO:0018342 18 7 0,000 0,0314143 0,07528168 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0314143 0,07520677 ! regulation of mitosis GO:0007088 105 63 1,000 0,03348941 0,08009495 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,03348941 0,08001541 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,03545898 0,0846372 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,03545898 0,08455331 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03582135 0,08533284 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03582135 0,08524843 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03582135 0,0851642 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03582135 0,08508012 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03582135 0,08499622 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03582135 0,08491248 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03582135 0,0848289 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03582135 0,08474549 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03582135 0,08466225 ! meiotic prophase I GO:0007128 13 8 0,000 0,03582135 0,08457916 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03582135 0,08449624 ! oligopeptide transport GO:0006857 15 8 0,000 0,03582135 0,08441348 ! UTP metabolic process GO:0046051 8 8 0,000 0,03582135 0,08433089 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03582135 0,08424845 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03582135 0,08416618 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03582135 0,08408406 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03582135 0,08400211 ! succinate metabolic process GO:0006105 14 8 0,000 0,03582135 0,08392032 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03582135 0,08383868 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03582135 0,08375721 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03582135 0,08367589 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03582135 0,08359473 ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03582135 0,08351373 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03582135 0,08343288 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03582135 0,08335219 ! reflex GO:0060004 16 8 0,000 0,03582135 0,08327166 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03582135 0,08319128 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03582135 0,08311106 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03582135 0,08303099 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03582135 0,08295107 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03582135 0,08287131 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03582135 0,08279171 ! pigment granule organization GO:0048753 16 8 0,000 0,03582135 0,08271225 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03582135 0,08263295 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03582135 0,0825538 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03582135 0,0824748 ! histidine metabolic process GO:0006547 16 8 0,000 0,03582135 0,08239595 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03582135 0,08231725 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03582135 0,08223871 ! glycine catabolic process GO:0006546 13 8 0,000 0,03582135 0,08216031 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03582135 0,08208206 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03582135 0,08200396 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,03582135 0,08192601 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03582135 0,08184821 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03582135 0,08177056 ! melanin metabolic process GO:0006582 15 8 0,000 0,03582135 0,08169305 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03582135 0,08161569 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03582135 0,08153847 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03582135 0,0814614 ! macrophage activation GO:0042116 12 8 0,000 0,03582135 0,08138448 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03582135 0,0813077 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03582135 0,08123107 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03582135 0,08115458 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03582135 0,08107824 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03582135 0,08100204 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03582135 0,08092598 ! osteoblast development GO:0002076 16 8 0,000 0,03582135 0,08085006 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03582135 0,08077429 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03582135 0,08069866 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03582135 0,08062317 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03582135 0,08054782 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03582135 0,08047261 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03582135 0,08039754 ! response to UV-B GO:0010224 16 8 0,000 0,03582135 0,08032261 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03582135 0,08024783 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03582135 0,08017318 ! intermediate filament organization GO:0045109 12 8 0,000 0,03582135 0,08009867 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03582135 0,08002429 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03582135 0,07995006 ! cellular extravasation GO:0045123 12 8 0,000 0,03582135 0,07987596 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03582135 0,07980201 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03582135 0,07972818 ! response to antibiotic GO:0046677 11 8 0,000 0,03582135 0,0796545 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03582135 0,07958095 ! DNA topological change GO:0006265 12 8 0,000 0,03582135 0,07950753 ! response to tropane GO:0014073 15 8 0,000 0,03582135 0,07943425 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03582135 0,07936111 ! melanosome transport GO:0032402 13 8 0,000 0,03582135 0,0792881 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03582135 0,07921523 ! mast cell activation GO:0045576 14 8 0,000 0,03582135 0,07914248 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03582135 0,07906988 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03582135 0,0789974 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03582135 0,07892506 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03582135 0,07885285 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03582135 0,07878077 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03582135 0,07870883 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03582135 0,07863701 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03582135 0,07856533 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03582135 0,07849378 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03582135 0,07842235 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03582135 0,07835106 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03582135 0,0782799 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03582135 0,07820886 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03582135 0,07813796 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03582135 0,07806718 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03582135 0,07799653 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03582135 0,07792601 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03582135 0,07785561 ! hormone catabolic process GO:0042447 17 8 0,000 0,03582135 0,07778535 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03582135 0,07771521 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03582135 0,07764519 ! ATP catabolic process GO:0006200 11 8 0,000 0,03582135 0,07757531 ! blastocyst growth GO:0001832 19 8 0,000 0,03582135 0,07750554 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03582135 0,07743591 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03582135 0,0773664 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03582135 0,07729701 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03582135 0,07722775 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03582135 0,07715861 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03582135 0,07708959 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03582135 0,0770207 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03582135 0,07695193 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03582135 0,07688329 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03582135 0,07681476 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03582135 0,07674636 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03582135 0,07667808 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03582135 0,07660992 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03582135 0,07654189 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03582135 0,07647397 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03582135 0,07640618 ! actin filament organization GO:0007015 148 66 1,000 0,03646025 0,07770006 ! secondary metabolic process GO:0019748 116 66 1,000 0,03646025 0,07763129 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,03747236 0,07971574 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,03747236 0,07964532 ! activation of MAPK activity GO:0000187 115 67 1,000 0,03747236 0,07957503 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,03849519 0,08167499 ! regulation of lipase activity GO:0060191 130 68 1,000 0,03849519 0,08160303 ! negative regulation of cell size GO:0045792 134 69 1,000 0,03952863 0,08371996 ! axon extension GO:0048675 15 9 0,000 0,04020849 0,08508499 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04020849 0,08501022 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04020849 0,08493558 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04020849 0,08486108 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04020849 0,08478671 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04020849 0,08471246 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04020849 0,08463835 ! phosphate transport GO:0006817 19 9 0,000 0,04020849 0,08456436 ! reproductive behavior GO:0019098 19 9 0,000 0,04020849 0,08449051 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04020849 0,08441678 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04020849 0,08434318 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04020849 0,08426971 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04020849 0,08419637 ! GTP metabolic process GO:0046039 9 9 0,000 0,04020849 0,08412316 ! RNA methylation GO:0001510 15 9 0,000 0,04020849 0,08405007 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04020849 0,08397711 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04020849 0,08390428 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04020849 0,08383157 ! artery development GO:0060840 24 9 0,000 0,04020849 0,08375899 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04020849 0,08368653 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04020849 0,0836142 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04020849 0,083542 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04020849 0,08346991 ! chemosensory behavior GO:0007635 20 9 0,000 0,04020849 0,08339796 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04020849 0,08332612 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04020849 0,08325442 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04020849 0,08318283 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04020849 0,08311137 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04020849 0,08304003 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04020849 0,08296881 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04020849 0,08289771 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04020849 0,08282674 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04020849 0,08275589 ! protein targeting to ER GO:0045047 22 9 0,000 0,04020849 0,08268515 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04020849 0,08261454 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04020849 0,08254405 ! T cell selection GO:0045058 23 9 0,000 0,04020849 0,08247368 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04020849 0,08240343 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04020849 0,0823333 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04020849 0,08226329 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04020849 0,0821934 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04020849 0,08212363 ! mannose metabolic process GO:0006013 13 9 0,000 0,04020849 0,08205397 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04020849 0,08198443 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04020849 0,08191501 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04020849 0,08184571 ! receptor clustering GO:0043113 18 9 0,000 0,04020849 0,08177653 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04020849 0,08170746 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04020849 0,08163851 ! ruffle organization GO:0031529 15 9 0,000 0,04020849 0,08156967 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04020849 0,08150095 ! behavioral fear response GO:0001662 22 9 0,000 0,04020849 0,08143235 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04020849 0,08136386 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04020849 0,08129549 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04020849 0,08122723 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04020849 0,08115909 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04020849 0,08109106 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04020849 0,08102314 ! segment specification GO:0007379 13 9 0,000 0,04020849 0,08095534 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04020849 0,08088765 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04020849 0,08082008 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04020849 0,08075261 ! response to amine stimulus GO:0014075 13 9 0,000 0,04020849 0,08068526 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04020849 0,08061803 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04020849 0,0805509 ! erythrocyte development GO:0048821 15 9 0,000 0,04020849 0,08048389 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04020849 0,08041698 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04020849 0,08035019 ! renal water homeostasis GO:0003091 14 9 0,000 0,04020849 0,08028351 ! postreplication repair GO:0006301 22 9 0,000 0,04020849 0,08021694 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04020849 0,08015048 ! icosanoid secretion GO:0032309 15 9 0,000 0,04020849 0,08008413 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04020849 0,08001789 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04020849 0,07995176 ! regulation of cell division GO:0051302 15 9 0,000 0,04020849 0,07988574 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04020849 0,07981983 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04020849 0,07975402 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04020849 0,07968833 ! sterol catabolic process GO:0016127 11 9 0,000 0,04020849 0,07962274 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04020849 0,07955726 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04020849 0,07949189 ! S phase GO:0051320 9 9 0,000 0,04020849 0,07942663 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04020849 0,07936147 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04020849 0,07929642 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04020849 0,07923147 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04020849 0,07916664 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04020849 0,07910191 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04020849 0,07903728 ! purine base metabolic process GO:0006144 21 9 0,000 0,04020849 0,07897276 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04020849 0,07890834 ! pigment granule transport GO:0051904 17 9 0,000 0,04020849 0,07884403 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04020849 0,07877983 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04020849 0,07871573 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04020849 0,07865173 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04020849 0,07858784 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04020849 0,07852405 ! mitochondrion localization GO:0051646 15 9 0,000 0,04020849 0,07846037 ! appendage morphogenesis GO:0035107 135 70 1,000 0,04057255 0,0791066 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,04162684 0,0810965 GO:0060173|limb development, ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,04269139 0,08310313 ! carbohydrate transport GO:0008643 110 72 1,000 0,04269139 0,08303595 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,04269139 0,08296888 ! learning or memory GO:0007611 147 73 1,000 0,04376608 0,08498884 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04457582 0,08649146 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,04457582 0,08642177 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04457582 0,08635219 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04457582 0,08628272 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04457582 0,08621336 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04457582 0,08614411 ! synapsis GO:0007129 13 10 0,000 0,04457582 0,08607497 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04457582 0,08600595 ! N-glycan processing GO:0006491 20 10 0,000 0,04457582 0,08593703 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04457582 0,08586823 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04457582 0,08579953 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04457582 0,08573095 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04457582 0,08566247 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04457582 0,08559411 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04457582 0,08552585 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04457582 0,0854577 ! androgen metabolic process GO:0008209 17 10 0,000 0,04457582 0,08538966 ! phospholipid efflux GO:0033700 16 10 0,000 0,04457582 0,08532173 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04457582 0,08525391 ! lung alveolus development GO:0048286 26 10 0,000 0,04457582 0,08518619 ! pathogenesis GO:0009405 13 10 0,000 0,04457582 0,08511858 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04457582 0,08505108 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04457582 0,08498369 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04457582 0,0849164 ! endoderm development GO:0007492 16 10 0,000 0,04457582 0,08484922 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04457582 0,08478215 ! arginine catabolic process GO:0006527 13 10 0,000 0,04457582 0,08471518 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04457582 0,08464832 ! proline metabolic process GO:0006560 13 10 0,000 0,04457582 0,08458156 ! L-serine metabolic process GO:0006563 18 10 0,000 0,04457582 0,08451491 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04457582 0,08444836 ! V(D)J recombination GO:0033151 28 10 0,000 0,04457582 0,08438192 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04457582 0,08431558 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04457582 0,08424934 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04457582 0,08418321 ! B cell proliferation GO:0042100 18 10 0,000 0,04457582 0,08411719 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04457582 0,08405127 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04457582 0,08398545 ! multicellular organism growth GO:0035264 18 10 0,000 0,04457582 0,08391973 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04457582 0,08385412 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04457582 0,08378861 ! epithelial cell development GO:0002064 20 10 0,000 0,04457582 0,0837232 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04457582 0,08365789 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04457582 0,08359269 ! macroautophagy GO:0016236 17 10 0,000 0,04457582 0,08352758 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04457582 0,08346258 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04457582 0,08339768 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04457582 0,08333288 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04457582 0,08326818 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04457582 0,08320358 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04457582 0,08313908 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04457582 0,08307468 ! brain morphogenesis GO:0048854 23 10 0,000 0,04457582 0,08301038 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04457582 0,08294618 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04457582 0,08288208 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04457582 0,08281808 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04457582 0,08275418 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04457582 0,08269037 ! DNA ligation GO:0006266 19 10 0,000 0,04457582 0,08262667 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04457582 0,08256306 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04457582 0,08249955 ! melanosome localization GO:0032400 16 10 0,000 0,04457582 0,08243614 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04457582 0,08237282 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04457582 0,08230961 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04457582 0,08224648 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04457582 0,08218346 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04457582 0,08212053 ! mRNA cleavage GO:0006379 17 10 0,000 0,04457582 0,0820577 ! protein sumoylation GO:0016925 15 10 0,000 0,04457582 0,08199497 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04457582 0,08193233 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04457582 0,08186978 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04457582 0,08180733 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04457582 0,08174498 ! salivary gland development GO:0007431 27 10 0,000 0,04457582 0,08168272 ! prophase GO:0051324 15 10 0,000 0,04457582 0,08162056 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04457582 0,08155849 ! apical protein localization GO:0045176 15 10 0,000 0,04457582 0,08149652 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04457582 0,08143464 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04457582 0,08137285 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04457582 0,08131116 ! midbrain development GO:0030901 13 10 0,000 0,04457582 0,08124956 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04457582 0,08118805 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04457582 0,08112664 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04457582 0,08106532 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04457582 0,08100409 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04457582 0,08094296 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04457582 0,08088191 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04457582 0,08082096 ! detection of calcium ion GO:0005513 23 10 0,000 0,04457582 0,0807601 ! oocyte development GO:0048599 17 10 0,000 0,04457582 0,08069933 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04457582 0,08063866 ! blastocyst formation GO:0001825 17 10 0,000 0,04457582 0,08057807 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04457582 0,08051758 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04457582 0,08045718 ! activation of innate immune response GO:0002218 12 10 0,000 0,04457582 0,08039686 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04457582 0,08033664 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04457582 0,08027651 ! response to nicotine GO:0035094 20 10 0,000 0,04457582 0,08021647 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04457582 0,08015651 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04457582 0,08009665 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,04594544 0,08249606 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,04594544 0,08243454 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04594544 0,08237311 ! defense response to bacterium GO:0042742 89 76 1,000 0,04704988 0,0842904 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04892341 0,08758165 ! respiratory burst GO:0045730 17 11 0,000 0,04892341 0,08751653 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04892341 0,08745151 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04892341 0,08738659 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04892341 0,08732176 ! thyroid gland development GO:0030878 26 11 0,000 0,04892341 0,08725703 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04892341 0,0871924 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04892341 0,08712786 ! response to pain GO:0048265 24 11 0,000 0,04892341 0,08706341 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04892341 0,08699906 ! T cell proliferation GO:0042098 26 11 0,000 0,04892341 0,08693481 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04892341 0,08687065 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04892341 0,08680659 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04892341 0,08674262 ! bone resorption GO:0045453 16 11 0,000 0,04892341 0,08667874 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04892341 0,08661496 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04892341 0,08655128 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04892341 0,08648768 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04892341 0,08642418 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04892341 0,08636077 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04892341 0,08629746 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04892341 0,08623424 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04892341 0,08617111 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04892341 0,08610807 ! lipid digestion GO:0044241 18 11 0,000 0,04892341 0,08604513 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04892341 0,08598228 ! UV protection GO:0009650 19 11 0,000 0,04892341 0,08591951 ! adult heart development GO:0007512 14 11 0,000 0,04892341 0,08585685 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04892341 0,08579427 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04892341 0,08573178 ! temperature homeostasis GO:0001659 17 11 0,000 0,04892341 0,08566938 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04892341 0,08560708 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04892341 0,08554487 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04892341 0,08548274 ! regulation of organ growth GO:0046620 13 11 0,000 0,04892341 0,08542071 ! pigment granule localization GO:0051875 20 11 0,000 0,04892341 0,08535876 ! vasoconstriction GO:0042310 18 11 0,000 0,04892341 0,08529691 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04892341 0,08523514 ! embryonic axis specification GO:0000578 18 11 0,000 0,04892341 0,08517347 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04892341 0,08511188 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04892341 0,08505039 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04892341 0,08498898 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04892341 0,08492766 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04892341 0,08486643 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04892341 0,08480528 ! zymogen activation GO:0031638 15 11 0,000 0,04892341 0,08474423 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04892341 0,08468326 ! nucleosome positioning GO:0016584 15 11 0,000 0,04892341 0,08462238 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04892341 0,08456159 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04892341 0,08450089 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04892341 0,08444027 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04892341 0,08437974 ! acid secretion GO:0046717 18 11 0,000 0,04892341 0,08431929 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04892341 0,08425894 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04892341 0,08419867 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04892341 0,08413848 ! oocyte differentiation GO:0009994 18 11 0,000 0,04892341 0,08407838 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04892341 0,08401837 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04892341 0,08395844 ! cholesterol efflux GO:0033344 19 11 0,000 0,04892341 0,0838986 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04892341 0,08383884 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04892341 0,08377917 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04892341 0,08371958 ! embryonic gut development GO:0048566 15 11 0,000 0,04892341 0,08366008 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04892341 0,08360066 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04892341 0,08354133 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04892341 0,08348208 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04892341 0,08342292 ! defense response to fungus GO:0050832 13 11 0,000 0,04892341 0,08336383 ! lysogeny GO:0030069 21 11 0,000 0,04892341 0,08330484 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04892341 0,08324592 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04892341 0,08318709 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04892341 0,08312834 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04892341 0,08306968 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04892341 0,0830111 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,05042096 0,08549178 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,05042096 0,08543157 ! inorganic anion transport GO:0015698 138 80 1,000 0,05156354 0,08730603 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,05271538 0,08919353 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05325137 0,09003711 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05325137 0,08997388 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05325137 0,08991074 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05325137 0,08984769 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,05325137 0,08978472 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05325137 0,08972185 ! cartilage condensation GO:0001502 20 12 0,000 0,05325137 0,08965906 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05325137 0,08959636 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05325137 0,08953375 ! protein complex disassembly GO:0043241 27 12 0,000 0,05325137 0,08947123 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05325137 0,08940879 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05325137 0,08934644 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05325137 0,08928418 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05325137 0,08922201 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05325137 0,08915992 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05325137 0,08909791 ! drug transport GO:0015893 16 12 0,000 0,05325137 0,089036 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05325137 0,08897417 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05325137 0,08891242 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05325137 0,08885076 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05325137 0,08878919 ! focal adhesion formation GO:0048041 35 12 0,000 0,05325137 0,0887277 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05325137 0,0886663 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05325137 0,08860498 ! forebrain cell migration GO:0021885 21 12 0,000 0,05325137 0,08854375 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05325137 0,0884826 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05325137 0,08842153 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05325137 0,08836055 ! fear response GO:0042596 26 12 0,000 0,05325137 0,08829966 ! monoamine transport GO:0015844 18 12 0,000 0,05325137 0,08823884 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05325137 0,08817811 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05325137 0,08811747 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05325137 0,08805691 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05325137 0,08799643 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05325137 0,08793603 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05325137 0,08787572 ! protein homotetramerization GO:0051289 21 12 0,000 0,05325137 0,08781549 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05325137 0,08775534 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05325137 0,08769528 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05325137 0,08763529 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05325137 0,08757539 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05325137 0,08751557 ! cranial nerve development GO:0021545 20 12 0,000 0,05325137 0,08745584 ! fucose catabolic process GO:0019317 22 12 0,000 0,05325137 0,08739618 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05325137 0,08733661 ! histone methylation GO:0016571 26 12 0,000 0,05325137 0,08727711 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05325137 0,0872177 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05325137 0,08715837 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05325137 0,08709912 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05325137 0,08703995 ! spleen development GO:0048536 22 12 0,000 0,05325137 0,08698086 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05325137 0,08692185 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05325137 0,08686292 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05325137 0,08680407 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05325137 0,0867453 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05325137 0,0866866 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,05325137 0,08662799 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05325137 0,08656946 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05325137 0,08651101 ! response to cold GO:0009409 17 12 0,000 0,05325137 0,08645263 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05325137 0,08639434 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,05387637 0,08734943 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,05622541 0,09109653 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05755978 0,09319571 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05755978 0,09313304 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05755978 0,09307045 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05755978 0,09300794 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05755978 0,09294552 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05755978 0,09288318 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05755978 0,09282093 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05755978 0,09275876 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05755978 0,09269667 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05755978 0,09263467 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05755978 0,09257274 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05755978 0,09251091 ! methionine metabolic process GO:0006555 27 13 0,000 0,05755978 0,09244915 ! plasma membrane organization GO:0007009 24 13 0,000 0,05755978 0,09238748 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05755978 0,09232588 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05755978 0,09226437 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05755978 0,09220295 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05755978 0,0921416 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05755978 0,09208034 ! response to X-ray GO:0010165 25 13 0,000 0,05755978 0,09201915 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05755978 0,09195805 ! exocrine system development GO:0035272 32 13 0,000 0,05755978 0,09189703 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05755978 0,09183609 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05755978 0,09177523 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05755978 0,09171445 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05755978 0,09165376 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05755978 0,09159314 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05755978 0,0915326 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05755978 0,09147214 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05755978 0,09141177 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05755978 0,09135147 ! ribosome assembly GO:0042255 17 13 0,000 0,05755978 0,09129125 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05755978 0,09123111 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05755978 0,09117105 ! chromatin silencing GO:0006342 26 13 0,000 0,05755978 0,09111107 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05755978 0,09105117 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05755978 0,09099134 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05755978 0,0909316 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05755978 0,09087193 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05755978 0,09081234 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05755978 0,09075283 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05755978 0,0906934 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05755978 0,09063405 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05755978 0,09057477 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05755978 0,09051557 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05755978 0,09045645 ! embryonic placenta development GO:0001892 23 13 0,000 0,05755978 0,09039741 ! insulin secretion GO:0030073 23 13 0,000 0,05755978 0,09033844 ! actin filament polymerization GO:0030041 24 13 0,000 0,05755978 0,09027955 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05755978 0,09022073 ! acrosome reaction GO:0007340 18 13 0,000 0,05755978 0,090162 ! mitochondrion organization GO:0007005 148 86 1,000 0,05860982 0,09174705 ! regulation of protein transport GO:0051223 154 87 1,000 0,05981502 0,09357279 GO:0070201|regulation of establishment of protein localization, ! regulation of neurological system process GO:0031644 148 88 1,000 0,06102876 0,09540949 ! rRNA transcription GO:0009303 25 14 0,000 0,06184872 0,09662858 ! lactation GO:0007595 26 14 0,000 0,06184872 0,09656588 ! reproductive cellular process GO:0048610 20 14 0,000 0,06184872 0,09650326 ! tRNA modification GO:0006400 20 14 0,000 0,06184872 0,09644071 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06184872 0,09637825 ! regulation of S phase GO:0033261 23 14 0,000 0,06184872 0,09631587 ! water transport GO:0006833 21 14 0,000 0,06184872 0,09625357 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06184872 0,09619135 ! non-recombinational repair GO:0000726 25 14 0,000 0,06184872 0,09612921 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06184872 0,09606715 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06184872 0,09600517 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06184872 0,09594328 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06184872 0,09588146 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06184872 0,09581972 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06184872 0,09575806 ! palate development GO:0060021 31 14 0,000 0,06184872 0,09569648 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,06184872 0,09563497 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06184872 0,09557355 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06184872 0,09551221 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06184872 0,09545094 ! arginine metabolic process GO:0006525 17 14 0,000 0,06184872 0,09538976 ! regulation of heart rate GO:0002027 24 14 0,000 0,06184872 0,09532865 ! organic alcohol transport GO:0015850 29 14 0,000 0,06184872 0,09526762 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06184872 0,09520667 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06184872 0,09514579 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06184872 0,095085 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06184872 0,09502428 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06184872 0,09496364 ! L-amino acid transport GO:0015807 30 14 0,000 0,06184872 0,09490307 ! bone mineralization GO:0030282 17 14 0,000 0,06184872 0,09484259 ! stem cell development GO:0048864 43 14 0,000 0,06184872 0,09478218 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06184872 0,09472185 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06184872 0,09466159 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06184872 0,09460141 ! cerebellum development GO:0021549 21 14 0,000 0,06184872 0,09454131 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06184872 0,09448128 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06184872 0,09442133 ! response to gamma radiation GO:0010332 28 14 0,000 0,06184872 0,09436146 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06184872 0,09430166 ! cofactor transport GO:0051181 26 14 0,000 0,06184872 0,09424194 ! NADP metabolic process GO:0006739 24 14 0,000 0,06184872 0,09418229 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06184872 0,09412272 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06184872 0,09406322 ! intestinal absorption GO:0050892 25 14 0,000 0,06184872 0,0940038 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06184872 0,09394446 ! oxygen transport GO:0015671 21 14 0,000 0,06184872 0,09388519 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06184872 0,09382599 ! male genitalia development GO:0030539 24 14 0,000 0,06184872 0,09376687 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06184872 0,09370782 ! regulation of axon extension GO:0030516 37 14 0,000 0,06184872 0,09364885 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,06184872 0,09358995 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06184872 0,09353113 ! ossification GO:0001503 188 90 1,000 0,06348144 0,09593991 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,06348144 0,09587968 ! bone development GO:0060348 189 91 1,000 0,06472017 0,09768929 ! sterol metabolic process GO:0016125 152 91 1,000 0,06472017 0,09762804 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06611829 0,09967456 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06611829 0,09961214 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06611829 0,09954981 ! superoxide anion generation GO:0042554 20 15 0,000 0,06611829 0,09948755 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06611829 0,09942537 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06611829 0,09936327 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06611829 0,09930124 ! copper ion transport GO:0006825 20 15 0,000 0,06611829 0,0992393 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06611829 0,09917743 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06611829 0,09911564 ! response to cAMP GO:0051591 22 15 0,000 0,06611829 0,09905392 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06611829 0,09899228 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06611829 0,09893072 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06611829 0,09886923 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06611829 0,09880782 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06611829 0,09874649 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06611829 0,09868523 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06611829 0,09862405 ! vesicle coating GO:0006901 33 15 0,000 0,06611829 0,09856295 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06611829 0,09850192 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06611829 0,09844096 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,06611829 0,09838008 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06611829 0,09831928 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,06611829 0,09825855 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06611829 0,0981979 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06611829 0,09813732 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06611829 0,09807682 ! histone deacetylation GO:0016575 20 15 0,000 0,06611829 0,09801639 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06611829 0,09795603 ! tissue regeneration GO:0042246 26 15 0,000 0,06611829 0,09789575 ! water homeostasis GO:0030104 27 15 0,000 0,06611829 0,09783554 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06611829 0,09777541 ! muscle maintenance GO:0046716 26 15 0,000 0,06611829 0,09771535 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06611829 0,09765537 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06611829 0,09759546 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06611829 0,09753562 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06611829 0,09747585 ! detection of bacterium GO:0016045 18 15 0,000 0,06611829 0,09741616 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06611829 0,09735654 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06611829 0,097297 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06611829 0,09723753 ! peptide hormone processing GO:0016486 23 15 0,000 0,06611829 0,09717813 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,06722193 0,09873991 ! regulation of membrane potential GO:0042391 164 93 1,000 0,06722193 0,09867967 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07036856 0,10323583 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07036856 0,10317292 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07036856 0,10311008 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,07036856 0,10304733 ! bone remodeling GO:0046849 27 16 0,000 0,07036856 0,10298465 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07036856 0,10292204 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07036856 0,10285951 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07036856 0,10279706 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07036856 0,10273468 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07036856 0,10267238 ! startle response GO:0001964 28 16 0,000 0,07036856 0,10261016 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07036856 0,10254801 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07036856 0,10248593 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07036856 0,10242393 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07036856 0,10236201 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07036856 0,10230016 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,07036856 0,10223838 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,07036856 0,10217668 ! fructose metabolic process GO:0006000 25 16 0,000 0,07036856 0,10211505 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07036856 0,1020535 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07036856 0,10199202 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07036856 0,10193062 ! axon cargo transport GO:0008088 43 16 0,000 0,07036856 0,10186929 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07036856 0,10180803 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07036856 0,10174685 ! DNA replication initiation GO:0006270 27 16 0,000 0,07036856 0,10168574 ! neuron recognition GO:0008038 35 16 0,000 0,07036856 0,1016247 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07036856 0,10156374 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07036856 0,10150285 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07036856 0,10144204 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,07036856 0,10138129 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07036856 0,10132062 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07036856 0,10126002 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07036856 0,1011995 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07036856 0,10113904 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07036856 0,10107866 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07036856 0,10101835 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,07036856 0,10095811 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07036856 0,10089795 ! defense response to virus GO:0051607 37 16 0,000 0,07036856 0,10083785 ! detection of stimulus GO:0051606 151 96 1,000 0,07103387 0,10173064 ! protein ubiquitination GO:0016567 217 97 1,000 0,07231993 0,10351086 ! regulation of protein localization GO:0032880 176 97 1,000 0,07231993 0,10344932 ! response to virus GO:0009615 160 98 1,000 0,07361355 0,1052372 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07459963 0,10658356 ! metencephalon development GO:0022037 30 17 0,000 0,07459963 0,10652031 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07459963 0,10645713 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,07459963 0,10639402 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07459963 0,10633099 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07459963 0,10626804 ! signal complex assembly GO:0007172 41 17 0,000 0,07459963 0,10620516 ! endothelial cell migration GO:0043542 28 17 0,000 0,07459963 0,10614235 ! inositol metabolic process GO:0006020 28 17 0,000 0,07459963 0,10607962 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07459963 0,10601696 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07459963 0,10595438 ! glial cell development GO:0021782 27 17 0,000 0,07459963 0,10589187 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07459963 0,10582943 ! adult walking behavior GO:0007628 33 17 0,000 0,07459963 0,10576707 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07459963 0,10570478 ! heart looping GO:0001947 30 17 0,000 0,07459963 0,10564256 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07459963 0,10558042 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07459963 0,10551835 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07459963 0,10545636 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07459963 0,10539443 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07459963 0,10533258 ! glycine metabolic process GO:0006544 28 17 0,000 0,07459963 0,1052708 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07459963 0,1052091 ! NAD metabolic process GO:0019674 29 17 0,000 0,07459963 0,10514746 ! membrane budding GO:0006900 37 17 0,000 0,07459963 0,1050859 ! DNA integration GO:0015074 29 17 0,000 0,07459963 0,10502441 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07459963 0,10496299 ! regulation of protein binding GO:0043393 33 17 0,000 0,07459963 0,10490165 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07459963 0,10484037 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07459963 0,10477917 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07459963 0,10471804 ! genitalia development GO:0048806 30 17 0,000 0,07459963 0,10465698 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,07459963 0,10459599 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07459963 0,10453507 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07459963 0,10447422 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07459963 0,10441345 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07459963 0,10435274 ! steroid catabolic process GO:0006706 31 17 0,000 0,07459963 0,10429211 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07459963 0,10423154 ! gas transport GO:0015669 25 17 0,000 0,07459963 0,10417105 ! organic cation transport GO:0015695 31 17 0,000 0,07459963 0,10411062 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07459963 0,10405027 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07459963 0,10398999 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07459963 0,10392977 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07459963 0,10386963 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07459963 0,10380955 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07881159 0,10960733 ! neuron maturation GO:0042551 42 18 0,000 0,07881159 0,10954401 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07881159 0,10948076 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07881159 0,10941759 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07881159 0,10935449 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07881159 0,10929146 ! memory GO:0007613 31 18 0,000 0,07881159 0,1092285 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07881159 0,10916562 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07881159 0,10910281 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07881159 0,10904007 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07881159 0,1089774 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07881159 0,10891481 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07881159 0,10885229 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07881159 0,10878983 ! response to retinoic acid GO:0032526 26 18 0,000 0,07881159 0,10872745 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,07881159 0,10866515 ! response to fungus GO:0009620 21 18 0,000 0,07881159 0,10860291 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07881159 0,10854074 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07881159 0,10847865 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07881159 0,10841663 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07881159 0,10835468 ! vitamin transport GO:0051180 27 18 0,000 0,07881159 0,10829279 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07881159 0,10823098 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07881159 0,10816924 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07881159 0,10810757 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07881159 0,10804597 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07881159 0,10798444 ! nerve development GO:0021675 28 18 0,000 0,07881159 0,10792298 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07881159 0,10786159 ! protein secretion GO:0009306 39 19 0,000 0,08300451 0,11353545 ! positive regulation of translation GO:0045727 30 19 0,000 0,08300451 0,11347094 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08300451 0,11340651 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08300451 0,11334214 ! skin development GO:0043588 36 19 0,000 0,08300451 0,11327785 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08300451 0,11321364 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08300451 0,11314949 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08300451 0,11308542 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08300451 0,11302142 ! cerebral cortex development GO:0021987 36 19 0,000 0,08300451 0,1129575 ! pigmentation during development GO:0048066 41 19 0,000 0,08300451 0,11289364 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08300451 0,11282986 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,08300451 0,11276615 ! heme metabolic process GO:0042168 36 19 0,000 0,08300451 0,11270251 ! neuromuscular junction development GO:0007528 34 19 0,000 0,08300451 0,11263895 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08300451 0,11257545 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08300451 0,11251203 ! protein export from nucleus GO:0006611 36 19 0,000 0,08300451 0,11244868 ! heart process GO:0003015 30 19 0,000 0,08300451 0,1123854 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08300451 0,11232219 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08300451 0,11225905 ! cellular pigmentation GO:0033059 36 19 0,000 0,08300451 0,11219599 ! G1 phase GO:0051318 40 19 0,000 0,08300451 0,11213299 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08300451 0,11207007 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08300451 0,11200721 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08300451 0,11194443 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08300451 0,11188171 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08300451 0,11181907 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08300451 0,11175649 ! cilium assembly GO:0042384 37 19 0,000 0,08300451 0,11169399 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08300451 0,11163156 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08717849 0,11717958 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08717849 0,11711415 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08717849 0,1170488 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08717849 0,11698352 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08717849 0,11691831 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08717849 0,11685317 ! response to vitamin GO:0033273 31 20 0,000 0,08717849 0,11678811 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08717849 0,11672312 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08717849 0,1166582 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08717849 0,11659336 ! response to alkaloid GO:0043279 38 20 0,000 0,08717849 0,11652858 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08717849 0,11646388 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08717849 0,11639925 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08717849 0,11633469 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08717849 0,1162702 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08717849 0,11620579 ! body fluid secretion GO:0007589 31 20 0,000 0,08717849 0,11614144 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08717849 0,11607717 ! peptide secretion GO:0002790 35 20 0,000 0,08717849 0,11601297 ! stem cell differentiation GO:0048863 53 20 0,000 0,08717849 0,11594884 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08717849 0,11588478 ! sensory perception of pain GO:0019233 30 20 0,000 0,08717849 0,11582079 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08717849 0,11575687 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08717849 0,11569302 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08717849 0,11562924 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08717849 0,11556554 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08717849 0,1155019 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08717849 0,11543833 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08717849 0,11537483 ! regulation of glucose import GO:0046324 29 20 0,000 0,08717849 0,11531141 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08717849 0,11524805 ! actin filament-based movement GO:0030048 43 20 0,000 0,08717849 0,11518476 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,08717849 0,11512154 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08717849 0,11505839 ! negative regulation of translation GO:0017148 29 20 0,000 0,08717849 0,11499531 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,08717849 0,1149323 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,09133361 0,12034428 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09133361 0,12027841 ! hormone secretion GO:0046879 38 21 0,000 0,09133361 0,12021261 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09133361 0,12014689 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09133361 0,12008123 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,09133361 0,12001565 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09133361 0,11995014 ! axis specification GO:0009798 38 21 0,000 0,09133361 0,1198847 ! ovarian follicle development GO:0001541 35 21 0,000 0,09133361 0,11981933 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09133361 0,11975404 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09133361 0,11968881 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,09133361 0,11962366 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09133361 0,11955857 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09133361 0,11949356 ! vasodilation GO:0042311 39 21 0,000 0,09133361 0,11942862 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09133361 0,11936375 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09133361 0,11929895 ! oogenesis GO:0048477 36 21 0,000 0,09133361 0,11923421 ! DNA modification GO:0006304 34 21 0,000 0,09133361 0,11916955 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,09133361 0,11910496 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,09133361 0,11904044 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,09133361 0,11897599 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,09133361 0,11891161 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09133361 0,1188473 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,09133361 0,11878306 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,09133361 0,11871889 ! collagen catabolic process GO:0030574 28 21 0,000 0,09133361 0,11865478 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09133361 0,11859075 ! gut development GO:0048565 39 21 0,000 0,09133361 0,11852678 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09546995 0,12382787 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09546995 0,12376115 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09546995 0,1236945 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09546995 0,12362793 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09546995 0,12356143 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09546995 0,123495 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09546995 0,12342864 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09546995 0,12336235 ! regeneration GO:0031099 41 22 0,000 0,09546995 0,12329613 ! keratinization GO:0031424 28 22 0,000 0,09546995 0,12322998 ! sensory perception of taste GO:0050909 28 22 0,000 0,09546995 0,12316391 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,09546995 0,12309791 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09546995 0,12303197 ! vacuolar transport GO:0007034 36 22 0,000 0,09546995 0,12296611 ! lysosome organization GO:0007040 41 22 0,000 0,09546995 0,12290032 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09546995 0,12283459 ! fucose metabolic process GO:0006004 39 22 0,000 0,09546995 0,12276894 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09546995 0,12270336 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,09546995 0,12263785 ! ureteric bud development GO:0001657 43 22 0,000 0,09546995 0,12257241 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09546995 0,12250704 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09546995 0,12244173 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09546995 0,1223765 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09546995 0,12231134 ! sarcomere organization GO:0045214 30 22 0,000 0,09546995 0,12224624 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,09546995 0,12218122 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09546995 0,12211626 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09546995 0,12205138 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09546995 0,12198656 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,09546995 0,12192181 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09958759 0,12711287 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,09958759 0,12704547 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09958759 0,12697814 ! gluconeogenesis GO:0006094 33 23 0,000 0,09958759 0,12691089 ! viral genome replication GO:0019079 41 23 0,000 0,09958759 0,1268437 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09958759 0,12677659 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09958759 0,12670955 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09958759 0,12664258 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09958759 0,12657568 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09958759 0,12650885 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09958759 0,12644209 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,09958759 0,1263754 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,09958759 0,12630878 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09958759 0,12624223 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09958759 0,12617575 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09958759 0,12610934 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09958759 0,12604301 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09958759 0,12597674 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09958759 0,12591054 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,09958759 0,12584441 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09958759 0,12577835 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09958759 0,12571236 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09958759 0,12564644 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09958759 0,12558058 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09958759 0,1255148 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09958759 0,12544909 ! fatty acid transport GO:0015908 44 23 0,000 0,09958759 0,12538344 ! platelet activation GO:0030168 37 23 0,000 0,09958759 0,12531786 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09958759 0,12525235 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09958759 0,12518691 ! hormone transport GO:0009914 40 23 0,000 0,09958759 0,12512154 ! cell-cell recognition GO:0009988 25 23 0,000 0,09958759 0,12505624 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09958759 0,124991 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09958759 0,12492584 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,09958759 0,12486074 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09958759 0,1247957 GO:0006099|tricarboxylic acid cycle, ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,10368663 0,12986468 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10368663 0,12979711 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,10368663 0,12972961 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10368663 0,12966218 ! vacuole organization GO:0007033 43 24 0,000 0,10368663 0,12959483 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10368663 0,12952754 ! digestive system process GO:0022600 39 24 0,000 0,10368663 0,12946032 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10368663 0,12939318 ! regulation of behavior GO:0050795 43 24 0,000 0,10368663 0,1293261 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,10368663 0,12925909 ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,10368663 0,12919215 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10368663 0,12912528 ! pentose metabolic process GO:0019321 35 24 0,000 0,10368663 0,12905848 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10368663 0,12899175 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10368663 0,12892509 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10368663 0,12885849 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10368663 0,12879197 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10368663 0,12872551 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10368663 0,12865912 ! regulation of amine transport GO:0051952 40 24 0,000 0,10368663 0,12859281 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10776715 0,13358463 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,10776715 0,13351584 ! myelination GO:0042552 45 25 0,000 0,10776715 0,13344712 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10776715 0,13337848 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10776715 0,1333099 ! phototransduction GO:0007602 33 25 0,000 0,10776715 0,1332414 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10776715 0,13317296 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,10776715 0,1331046 ! sperm motility GO:0030317 31 25 0,000 0,10776715 0,13303631 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,10776715 0,13296808 ! receptor metabolic process GO:0043112 46 25 0,000 0,10776715 0,13289993 ! chromosome condensation GO:0030261 45 25 0,000 0,10776715 0,13283184 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10776715 0,13276383 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,10776715 0,13269589 ! neural crest cell development GO:0014032 54 25 0,000 0,10776715 0,13262801 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10776715 0,1325602 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10776715 0,13249247 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10776715 0,1324248 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10776715 0,1323572 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10776715 0,13228967 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10776715 0,13222221 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10776715 0,13215482 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10776715 0,1320875 ! telomere organization GO:0032200 43 25 0,000 0,10776715 0,13202024 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10776715 0,13195306 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11182922 0,13685713 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11182922 0,13678755 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,11182922 0,13671804 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,11182922 0,13664861 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,11182922 0,13657924 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11182922 0,13650995 ! tube lumen formation GO:0035148 50 26 0,000 0,11182922 0,13644072 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11182922 0,13637157 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11182922 0,13630249 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11182922 0,13623347 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,11182922 0,13616453 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,11182922 0,13609565 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,11182922 0,13602685 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11182922 0,13595811 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,11182922 0,13588945 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11182922 0,13582085 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,11182922 0,13575233 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11182922 0,13568387 ! blastocyst development GO:0001824 49 26 0,000 0,11182922 0,13561548 ! leukocyte proliferation GO:0070661 52 26 0,000 0,11182922 0,13554716 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11182922 0,13547891 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,11182922 0,13541072 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,11587294 0,14023656 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,11587294 0,14016606 ! iron ion transport GO:0006826 59 27 0,000 0,11587294 0,14009562 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,11587294 0,14002526 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,11587294 0,13995496 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,11587294 0,13988474 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,11587294 0,13981459 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,11587294 0,1397445 ! autophagy GO:0006914 41 27 0,000 0,11587294 0,13967449 ! male gonad development GO:0008584 44 27 0,000 0,11587294 0,13960455 ! response to toxin GO:0009636 47 27 0,000 0,11587294 0,13953468 ! primary neural tube formation GO:0014020 51 27 0,000 0,11587294 0,13946487 ! base-excision repair GO:0006284 41 27 0,000 0,11587294 0,13939514 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,11587294 0,13932548 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,11587294 0,13925589 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,11587294 0,13918636 ! glutathione metabolic process GO:0006749 39 27 0,000 0,11587294 0,13911691 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,11587294 0,13904752 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,11587294 0,13897821 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,11989837 0,14373467 ! circadian rhythm GO:0007623 50 28 0,000 0,11989837 0,14366309 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11989837 0,14359158 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,11989837 0,14352014 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11989837 0,14344877 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,11989837 0,14337748 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,11989837 0,14330625 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,11989837 0,1432351 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11989837 0,14316401 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11989837 0,143093 ! synaptogenesis GO:0007416 42 28 0,000 0,11989837 0,14302206 ! lipid oxidation GO:0034440 43 28 0,000 0,11989837 0,14295118 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11989837 0,14288038 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,11989837 0,14280965 ! translational initiation GO:0006413 65 29 0,000 0,12390562 0,14750961 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12390562 0,14743665 ! regulation of pH GO:0006885 43 29 0,000 0,12390562 0,14736377 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,12390562 0,14729096 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12390562 0,14721823 ! catechol metabolic process GO:0009712 54 29 0,000 0,12390562 0,14714556 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12390562 0,14707297 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12390562 0,14700045 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,12390562 0,146928 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12390562 0,14685562 ! detection of light stimulus GO:0009583 38 29 0,000 0,12390562 0,14678331 ! tissue homeostasis GO:0001894 48 29 0,000 0,12390562 0,14671108 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,12789475 0,15135994 ! zinc ion transport GO:0006829 45 30 0,000 0,12789475 0,15128553 ! cell junction assembly GO:0034329 78 30 0,000 0,12789475 0,15121118 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12789475 0,15113691 ! acute-phase response GO:0006953 49 30 0,000 0,12789475 0,15106272 ! myofibril assembly GO:0030239 47 30 0,000 0,12789475 0,1509886 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12789475 0,15091455 ! phospholipid transport GO:0015914 51 30 0,000 0,12789475 0,15084057 ! ensheathment of neurons GO:0007272 57 30 0,000 0,12789475 0,15076666 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12789475 0,15069283 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12789475 0,15061907 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,12789475 0,15054538 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12789475 0,15047176 ! eye morphogenesis GO:0048592 60 30 0,000 0,12789475 0,15039822 ! regulation of B cell activation GO:0050864 50 30 0,000 0,12789475 0,15032475 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,13186584 0,15491661 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,13186584 0,154841 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,13186584 0,15476547 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,13186584 0,15469001 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,13186584 0,15461463 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,13186584 0,15453932 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,13186584 0,15446408 ! ovulation cycle process GO:0022602 49 31 0,000 0,13186584 0,15438891 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,13186584 0,15431382 ! peptide transport GO:0015833 55 31 0,000 0,13186584 0,1542388 ! iron ion homeostasis GO:0055072 54 31 0,000 0,13186584 0,15416386 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,13186584 0,15408898 ! mesoderm formation GO:0001707 69 31 0,000 0,13186584 0,15401418 ! natural killer cell activation GO:0030101 45 31 0,000 0,13186584 0,15393946 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,13186584 0,1538648 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,13186584 0,15379022 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,13186584 0,15371571 GO:0043433|negative regulation of transcription factor activity, ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13581899 0,15824721 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13581899 0,15817062 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13581899 0,15809409 ! spliceosome assembly GO:0000245 67 32 0,000 0,13581899 0,15801765 ! spindle organization GO:0007051 46 32 0,000 0,13581899 0,15794127 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13581899 0,15786497 ! metanephros development GO:0001656 74 32 0,000 0,13581899 0,15778874 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13581899 0,15771259 ! response to ionizing radiation GO:0010212 65 32 0,000 0,13581899 0,15763651 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,13581899 0,15756051 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,13581899 0,15748457 ! muscle cell development GO:0055001 49 32 0,000 0,13581899 0,15740871 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,13581899 0,15733293 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13581899 0,15725721 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,13581899 0,15718157 ! ovulation cycle GO:0042698 51 32 0,000 0,13581899 0,15710601 ! peripheral nervous system development GO:0007422 64 32 0,000 0,13581899 0,15703051 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13581899 0,15695509 ! hindbrain development GO:0030902 61 32 0,000 0,13581899 0,15687974 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13581899 0,15680446 ! gene silencing GO:0016458 65 32 0,000 0,13581899 0,15672925 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,13975427 0,16119308 ! post-embryonic development GO:0009791 69 33 0,000 0,13975427 0,16111584 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,13975427 0,16103868 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13975427 0,16096159 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13975427 0,16088458 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13975427 0,16080764 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13975427 0,16073077 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13975427 0,16065397 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13975427 0,16057725 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13975427 0,1605006 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,13975427 0,16042403 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13975427 0,16034753 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,14367175 0,1647637 ! glial cell differentiation GO:0010001 63 34 0,000 0,14367175 0,1646852 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,14367175 0,16460678 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,14367175 0,16452843 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,14367175 0,16445016 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,14367175 0,16437196 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,14367175 0,16429384 ! mismatch repair GO:0006298 46 34 0,000 0,14367175 0,16421579 ! spermatid development GO:0007286 63 34 0,000 0,14367175 0,16413782 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,14367175 0,16405991 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,14367175 0,16398209 ! regulation of muscle development GO:0048634 70 35 0,000 0,14757153 0,1683533 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,14757153 0,16827351 ! negative regulation of secretion GO:0051048 63 35 0,000 0,14757153 0,16819379 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,14757153 0,16811416 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,14757153 0,1680346 ! odontogenesis GO:0042476 66 35 0,000 0,14757153 0,16795511 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14757153 0,1678757 ! female gonad development GO:0008585 58 35 0,000 0,14757153 0,16779636 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,14757153 0,1677171 ! neural tube formation GO:0001841 67 35 0,000 0,14757153 0,16763791 ! vesicle localization GO:0051648 64 35 0,000 0,14757153 0,1675588 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,15145368 0,17188563 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,15145368 0,17180459 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,15145368 0,17172363 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,15145368 0,17164274 ! cell junction organization GO:0034330 86 36 0,000 0,15145368 0,17156193 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,15145368 0,1714812 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,15145368 0,17140054 ! positive regulation of cell development GO:0010720 80 36 0,000 0,15145368 0,17131995 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,15145368 0,17123945 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,15145368 0,17115901 ! aerobic respiration GO:0009060 55 36 0,000 0,15145368 0,17107866 ! embryonic organ development GO:0048568 57 36 0,000 0,15145368 0,17099838 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,15145368 0,17091817 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,15145368 0,17083804 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15531827 0,17511516 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,15531827 0,17503314 ! meiosis I GO:0007127 65 37 0,000 0,15531827 0,1749512 ! sister chromatid segregation GO:0000819 58 37 0,000 0,15531827 0,17486933 ! organic anion transport GO:0015711 68 37 0,000 0,15531827 0,17478754 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,15531827 0,17470582 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,15531827 0,17462418 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15531827 0,17454262 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15531827 0,17446114 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,15531827 0,17437973 ! spermatid differentiation GO:0048515 66 37 0,000 0,15531827 0,17429839 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,15916539 0,17853237 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,15916539 0,17844917 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,15916539 0,17836606 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,15916539 0,17828302 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,15916539 0,17820006 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,15916539 0,17811718 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,15916539 0,17803437 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,15916539 0,17795164 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,15916539 0,17786899 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,15916539 0,17778641 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,15916539 0,17770391 ! mRNA catabolic process GO:0006402 71 39 0,000 0,16299512 0,18189529 ! ear morphogenesis GO:0042471 60 39 0,000 0,16299512 0,18181096 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,16299512 0,18172671 ! ion transmembrane transport GO:0034220 66 39 0,000 0,16299512 0,18164254 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,16299512 0,18155845 ! RNA modification GO:0009451 57 39 0,000 0,16299512 0,18147443 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,16299512 0,1813905 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,16680753 0,18554735 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,16680753 0,1854616 ! negative regulation of binding GO:0051100 72 40 0,000 0,16680753 0,18537594 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,16680753 0,18529035 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,16680753 0,18520485 ! maintenance of protein location GO:0045185 91 40 0,000 0,16680753 0,18511942 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1706027 0,18924393 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,1706027 0,18915672 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,1706027 0,1890696 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1706027 0,18898255 ! gliogenesis GO:0042063 88 41 0,000 0,1706027 0,18889558 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,1706027 0,18880869 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,1706027 0,18872188 ! female gamete generation GO:0007292 61 41 0,000 0,1706027 0,18863515 ! polyol metabolic process GO:0019751 66 41 0,000 0,1706027 0,1885485 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,1706027 0,18846193 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,17438071 0,19254703 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,17438071 0,19245871 ! regulation of tube size GO:0035150 71 42 0,000 0,17438071 0,19237046 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,17438071 0,1922823 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,17438071 0,19219422 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,17438071 0,19210622 ! neuron migration GO:0001764 79 42 0,000 0,17438071 0,1920183 ! regulation of protein secretion GO:0050708 71 42 0,000 0,17438071 0,19193046 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,17814163 0,19598023 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,17814163 0,19589066 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,17814163 0,19580117 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,17814163 0,19571177 ! neural tube development GO:0021915 77 43 0,000 0,17814163 0,19562244 ! striated muscle contraction GO:0006941 77 43 0,000 0,17814163 0,1955332 ! phagocytosis GO:0006909 90 43 0,000 0,17814163 0,19544404 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,17814163 0,19535495 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,18188555 0,19936977 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,18188555 0,19927898 ! male sex differentiation GO:0046661 76 44 0,000 0,18188555 0,19918827 ! double-strand break repair GO:0006302 81 44 0,000 0,18188555 0,19909765 ! biopolymer methylation GO:0043414 84 44 0,000 0,18188555 0,19900711 ! B cell differentiation GO:0030183 107 44 0,000 0,18188555 0,19891665 ! maintenance of location in cell GO:0051651 97 44 0,000 0,18188555 0,19882628 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,18561254 0,20280825 ! glycolysis GO:0006096 65 45 0,000 0,18561254 0,20271619 ! leukocyte migration GO:0050900 68 45 0,000 0,18561254 0,20262421 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,18561254 0,20253232 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,18561254 0,20244051 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,18561254 0,20234879 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,18561254 0,20225714 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18561254 0,20216558 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,18561254 0,2020741 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,18932267 0,20602006 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,18932267 0,20592692 ! pigmentation GO:0043473 100 46 0,000 0,18932267 0,20583387 ! positive regulation of defense response GO:0031349 76 47 0,000 0,19301602 0,20975454 ! response to calcium ion GO:0051592 81 47 0,000 0,19301602 0,20965984 ! endosome transport GO:0016197 108 47 0,000 0,19301602 0,20956523 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,19301602 0,2094707 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,19301602 0,20937626 ! JNK cascade GO:0007254 91 47 0,000 0,19301602 0,20928191 ! methylation GO:0032259 90 47 0,000 0,19301602 0,20918764 ! mitochondrial transport GO:0006839 82 48 0,000 0,19669267 0,21307635 ! Notch signaling pathway GO:0007219 96 48 0,000 0,19669267 0,21298045 ! cellular component disassembly GO:0022411 86 48 0,000 0,19669267 0,21288465 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,19669267 0,21278892 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,19669267 0,21269329 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,19669267 0,21259774 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,19669267 0,21250227 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,19669267 0,2124069 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,20035269 0,21626226 ! regulation of action potential GO:0001508 95 49 0,000 0,20035269 0,21616528 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,20035269 0,21606839 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,20035269 0,21597158 ! regulation of ion transport GO:0043269 77 49 0,000 0,20035269 0,21587486 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,20035269 0,21577823 ! peptide metabolic process GO:0006518 76 49 0,000 0,20035269 0,21568169 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,20035269 0,21558523 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,20035269 0,21548886 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,20035269 0,21539257 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,20035269 0,21529637 ! regulation of ossification GO:0030278 117 50 0,000 0,20399615 0,21911373 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,20399615 0,21901595 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,20762314 0,22281056 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,20762314 0,22271122 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,20762314 0,22261197 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,20762314 0,22251281 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,20762314 0,22241374 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,20762314 0,22231476 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,20762314 0,22221587 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,21123372 0,22597969 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,21123372 0,22587925 ! amino acid activation GO:0043038 92 52 0,000 0,21123372 0,22577891 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,21123372 0,22567865 ! synapse organization GO:0050808 85 52 0,000 0,21123372 0,22557848 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,21482796 0,22931503 ! RNA catabolic process GO:0006401 93 53 0,000 0,21482796 0,22921334 ! regulation of translational initiation GO:0006446 82 53 0,000 0,21482796 0,22911173 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,21482796 0,22901022 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,21482796 0,2289088 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,21482796 0,22880747 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,21840595 0,23251536 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,21840595 0,23241252 ! cell recognition GO:0008037 85 54 0,000 0,21840595 0,23230977 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,21840595 0,23220712 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,21840595 0,23210455 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,21840595 0,23200208 ! chloride transport GO:0006821 90 55 0,000 0,22196775 0,23568155 ! glucose catabolic process GO:0006007 82 55 0,000 0,22196775 0,23557759 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,22196775 0,23547372 ! gastrulation GO:0007369 112 55 0,000 0,22196775 0,23536994 ! RNA elongation GO:0006354 79 55 0,000 0,22196775 0,23526625 ! nuclear export GO:0051168 97 55 0,000 0,22196775 0,23516266 ! regulation of actin filament length GO:0030832 105 56 0,000 0,22551343 0,23881396 ! sensory perception of smell GO:0007608 80 56 0,000 0,22551343 0,2387089 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,22551343 0,23860392 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,22551343 0,23849904 ! proton transport GO:0015992 94 56 0,000 0,22551343 0,23839425 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,22904308 0,24201917 ! maintenance of location GO:0051235 118 57 0,000 0,22904308 0,24191293 ! hydrogen transport GO:0006818 97 58 0,000 0,23255675 0,24551626 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,23255675 0,24540857 ! regulation of cellular component size GO:0032535 109 59 0,000 0,23605453 0,24899044 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,23605453 0,24888133 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,23605453 0,24877232 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,23605453 0,2486634 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,23605453 0,24855458 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,23953648 0,25211058 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,23953648 0,25200034 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,23953648 0,2518902 ! regulation of heart contraction GO:0008016 110 60 0,000 0,23953648 0,25178016 ! camera-type eye development GO:0043010 116 60 0,000 0,23953648 0,25167021 ! kidney development GO:0001822 122 60 0,000 0,23953648 0,25156036 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,24300268 0,2550892 ! mesoderm development GO:0007498 119 61 0,000 0,24300268 0,25497796 ! tRNA processing GO:0008033 89 61 0,000 0,24300268 0,25486681 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,24300268 0,25475575 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,2464532 0,25826062 ! gonad development GO:0008406 98 62 0,000 0,2464532 0,25814819 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,2464532 0,25803585 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,2498881 0,26151838 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,2498881 0,26140468 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,25330745 0,26486646 ! cell redox homeostasis GO:0045454 102 64 0,000 0,25330745 0,2647514 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,25330745 0,26463644 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,25330745 0,26452158 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,25671133 0,26795986 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,26009981 0,27137908 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,26009981 0,27126144 ! extracellular matrix organization GO:0030198 133 66 0,000 0,26009981 0,27114391 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,26347296 0,27454133 ! chromosome segregation GO:0007059 113 67 0,000 0,26347296 0,27442248 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,26347296 0,27430373 ! hexose catabolic process GO:0019320 104 67 0,000 0,26347296 0,27418509 ! amino acid transport GO:0006865 125 68 0,000 0,26683083 0,27755944 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,26683083 0,27743949 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,26683083 0,27731965 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,26683083 0,27719991 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,27017351 0,28055135 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,27017351 0,28043031 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,27017351 0,28030939 ! urogenital system development GO:0001655 137 69 0,000 0,27017351 0,28018856 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,27017351 0,28006785 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,27017351 0,27994723 ! antigen processing and presentation GO:0019882 104 69 0,000 0,27017351 0,27982672 ! amine catabolic process GO:0009310 117 71 0,000 0,27681355 0,28658064 ! reproductive structure development GO:0048608 113 71 0,000 0,27681355 0,28645738 ! B cell activation GO:0042113 160 71 0,000 0,27681355 0,28633422 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,28011105 0,28962062 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,28011105 0,28949621 ! regulation of blood pressure GO:0008217 125 73 0,000 0,28339362 0,29276301 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,28339362 0,29263736 ! axon guidance GO:0007411 139 73 0,000 0,28339362 0,29251181 ! fertilization GO:0009566 90 73 0,000 0,28339362 0,29238638 ! transition metal ion transport GO:0000041 126 74 0,000 0,28666133 0,29563101 ! neurotransmitter transport GO:0006836 123 74 0,000 0,28666133 0,29550435 ! meiosis GO:0007126 121 74 0,000 0,28666133 0,29537779 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,28666133 0,29525135 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,28666133 0,29512501 ! eye development GO:0001654 143 74 0,000 0,28666133 0,29499878 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,28991424 0,29821876 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,28991424 0,29809131 ! meiotic cell cycle GO:0051321 122 75 0,000 0,28991424 0,29796398 ! rhythmic process GO:0048511 128 75 0,000 0,28991424 0,29783675 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,29315243 0,30103489 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,29315243 0,30090647 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,29315243 0,30077815 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,29315243 0,30064994 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,29637597 0,30382641 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,29637597 0,30369701 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,29637597 0,30356772 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,2995849 0,30672395 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,2995849 0,30659348 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,2995849 0,30646313 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,30277931 0,30959925 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,30277931 0,30946773 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,30595926 0,31258513 ! response to metal ion GO:0010038 140 80 0,000 0,30595926 0,31245245 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,30595926 0,31231989 ! digestion GO:0007586 112 81 0,000 0,30912481 0,31541743 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,30912481 0,31528372 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,31227602 0,31836276 ! response to drug GO:0042493 143 82 0,000 0,31227602 0,31822792 ! response to nutrient GO:0007584 125 82 0,000 0,31227602 0,31809319 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,31227602 0,31795858 ! regulation of lyase activity GO:0051339 160 83 0,000 0,31541297 0,32101675 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,31853571 0,3240579 ! negative regulation of transport GO:0051051 153 84 0,000 0,31853571 0,32392093 ! negative regulation of growth GO:0045926 155 84 0,000 0,31853571 0,32378408 ! regulation of ligase activity GO:0051340 142 84 0,000 0,31853571 0,32364735 ! response to unfolded protein GO:0006986 131 85 0,000 0,32164431 0,32666788 ! nucleosome assembly GO:0006334 122 85 0,000 0,32164431 0,32653005 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,32164431 0,32639233 ! amine biosynthetic process GO:0009309 138 86 0,000 0,32473884 0,32939361 ! response to inorganic substance GO:0010035 153 86 0,000 0,32473884 0,3292548 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,32473884 0,32911611 ! chromatin assembly GO:0031497 124 86 0,000 0,32473884 0,32897753 ! tube morphogenesis GO:0035239 176 86 0,000 0,32473884 0,32883907 ! alcohol catabolic process GO:0046164 130 86 0,000 0,32473884 0,32870073 ! amine transport GO:0015837 155 86 0,000 0,32473884 0,32856251 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,32781935 0,33153987 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,32781935 0,33140057 ! cellular respiration GO:0045333 135 88 0,000 0,3308859 0,33436014 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,3308859 0,33421977 ! cellular defense response GO:0006968 114 89 0,000 0,33393857 0,33716165 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,33393857 0,33702022 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,33393857 0,33687891 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,33697742 0,33980204 ! sex differentiation GO:0007548 145 90 0,000 0,33697742 0,33965969 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,33697742 0,33951745 ! response to protein stimulus GO:0051789 149 91 0,000 0,3400025 0,34242194 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,3400025 0,34227867 ! regulation of defense response GO:0031347 149 92 0,000 0,34301388 0,34516578 ! nucleosome organization GO:0034728 138 92 0,000 0,34301388 0,34502148 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,34301388 0,3448773 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,34601162 0,34774601 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,34601162 0,34760081 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,34899578 0,35045235 ! female pregnancy GO:0007565 164 94 0,000 0,34899578 0,35030615 ! transcription initiation GO:0006352 153 94 0,000 0,34899578 0,35016007 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,35196642 0,35299341 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,3549236 0,35581091 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,3549236 0,35566272 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,35786739 0,35846334 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,36079784 0,36124828 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,36079784 0,36109801 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,36371502 0,36386625 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,36371502 0,36371502