pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/517-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 7,602E-10 1,857E-06 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 4,000 3,229E-08 3,945E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 4,000 1,831E-07 1,491E-04 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 2,671E-07 1,632E-04 ! carbohydrate homeostasis GO:0033500 59 39 4,000 8,562E-07 4,184E-04 GO:0042593|glucose homeostasis, ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 3,000 8,769E-07 3,57E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 3,000 1,124E-06 3,921E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 1,74E-06 5,312E-04 ! nuclear migration GO:0007097 13 6 2,000 1,74E-06 4,722E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 1,74E-06 4,25E-04 GO:0031272|regulation of pseudopodium assembly, ! pancreas development GO:0031016 40 20 3,000 1,767E-06 3,923E-04 ! cell growth GO:0016049 90 46 4,000 1,988E-06 4,047E-04 ! response to insulin stimulus GO:0032868 98 47 4,000 2,216E-06 4,165E-04 ! inner ear receptor cell differentiation GO:0060113 42 22 3,000 2,649E-06 4,622E-04 ! positive regulation of protein ubiquitination GO:0031398 14 7 2,000 3,034E-06 4,942E-04 ! mechanoreceptor differentiation GO:0042490 48 24 3,000 3,821E-06 5,834E-04 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 4,000 4,058E-06 5,831E-04 ! myeloid leukocyte differentiation GO:0002573 46 25 3,000 4,533E-06 6,152E-04 ! regulation of insulin secretion GO:0050796 42 25 3,000 4,533E-06 5,828E-04 ! interaction with host GO:0051701 66 25 3,000 4,533E-06 5,536E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 4,839E-06 5,629E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 4,839E-06 5,373E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 4,839E-06 5,139E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 4,839E-06 4,925E-04 ! forebrain development GO:0030900 210 98 5,000 5,463E-06 5,339E-04 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 6,245E-06 5,867E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 7,234E-06 6,545E-04 ! macrophage differentiation GO:0030225 15 9 2,000 7,234E-06 6,312E-04 ! regulation of peptide secretion GO:0002791 52 29 3,000 8,392E-06 7,07E-04 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 1,036E-05 8,438E-04 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 1,036E-05 8,166E-04 ! positive regulation of cell motion GO:0051272 157 65 4,000 1,118E-05 8,539E-04 ! regulation of lipid metabolic process GO:0019216 132 66 4,000 1,206E-05 8,927E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 1,412E-05 1,014E-03 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 1,412E-05 9,853E-04 ! neuroblast proliferation GO:0007405 25 11 2,000 1,412E-05 9,58E-04 ! nucleus localization GO:0051647 22 11 2,000 1,412E-05 9,321E-04 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 3,000 1,61E-05 1,035E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 1,876E-05 1,175E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 1,876E-05 1,146E-03 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 1,876E-05 1,118E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 2,431E-05 1,414E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 2,528E-05 1,436E-03 ! protein oligomerization GO:0051259 149 79 4,000 2,902E-05 1,611E-03 ! activation of protein kinase activity GO:0032147 170 80 4,000 3,084E-05 1,674E-03 ! response to hypoxia GO:0001666 178 81 4,000 3,275E-05 1,74E-03 ! regulation of hormone secretion GO:0046883 69 41 3,000 3,432E-05 1,784E-03 ! response to oxygen levels GO:0070482 183 83 4,000 3,685E-05 1,876E-03 ! regulation of T cell mediated immunity GO:0002709 36 15 2,000 3,842E-05 1,915E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 3,842E-05 1,877E-03 ! regulation of protein ubiquitination GO:0031396 28 16 2,000 4,713E-05 2,258E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 4,713E-05 2,214E-03 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 2,000 4,713E-05 2,172E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 4,979E-05 2,253E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 5,435E-05 2,414E-03 ! filopodium assembly GO:0046847 42 17 2,000 5,704E-05 2,488E-03 ! myoblast differentiation GO:0045445 50 17 2,000 5,704E-05 2,445E-03 ! microspike assembly GO:0030035 46 18 2,000 6,822E-05 2,874E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 8,075E-05 3,344E-03 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 2,000 8,075E-05 3,288E-03 ! leukocyte differentiation GO:0002521 232 98 4,000 8,167E-05 3,271E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 8,99E-05 3,542E-03 GO:0060538|skeletal muscle organ development, ! regulation of carbohydrate metabolic process GO:0006109 37 20 2,000 9,469E-05 3,672E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of interleukin-2 production GO:0032663 39 20 2,000 9,469E-05 3,614E-03 ! inner ear development GO:0048839 89 53 3,000 9,518E-05 3,577E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 1,355E-04 5,017E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 1,457E-04 5,311E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 1,659E-04 5,961E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 1,659E-04 5,874E-03 ! regulation of protein complex assembly GO:0043254 132 63 3,000 1,87E-04 6,527E-03 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 1,000 1,971E-04 6,782E-03 ! neuron fate determination GO:0048664 7 5 1,000 1,971E-04 6,688E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,971E-04 6,596E-03 ! anagen GO:0042640 7 5 1,000 1,971E-04 6,507E-03 ! microvillus organization GO:0032528 8 5 1,000 1,971E-04 6,42E-03 GO:0030033|microvillus assembly, ! muscle cell migration GO:0014812 8 5 1,000 1,971E-04 6,336E-03 ! regulation of response to food GO:0032095 7 5 1,000 1,971E-04 6,254E-03 ! response to food GO:0032094 6 5 1,000 1,971E-04 6,173E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 1,971E-04 6,095E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,971E-04 6,019E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 1,971E-04 5,945E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 1,971E-04 5,872E-03 ! cellular glucose homeostasis GO:0001678 6 5 1,000 1,971E-04 5,801E-03 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 1,971E-04 5,732E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! regulation of sterol transport GO:0032371 7 5 1,000 1,971E-04 5,665E-03 GO:0032374|regulation of cholesterol transport, ! protein insertion into membrane GO:0051205 17 5 1,000 1,971E-04 5,599E-03 ! regulation of cellular ketone metabolic process GO:0010565 51 26 2,000 2,117E-04 5,946E-03 ! regulation of blood coagulation GO:0030193 46 26 2,000 2,117E-04 5,878E-03 ! ear development GO:0043583 114 66 3,000 2,239E-04 6,147E-03 ! myeloid cell differentiation GO:0030099 126 67 3,000 2,373E-04 6,442E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 2,374E-04 6,374E-03 ! cell projection assembly GO:0030031 138 68 3,000 2,513E-04 6,673E-03 ! neuron fate commitment GO:0048663 52 28 2,000 2,65E-04 6,962E-03 ! fat cell differentiation GO:0045444 57 28 2,000 2,65E-04 6,888E-03 ! lung development GO:0030324 165 69 3,000 2,658E-04 6,836E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 2,658E-04 6,764E-03 ! negative regulation of neuron differentiation GO:0045665 46 29 2,000 2,947E-04 7,421E-03 ! regulation of interferon-beta production GO:0032648 8 6 1,000 2,948E-04 7,349E-03 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,948E-04 7,274E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,948E-04 7,202E-03 GO:0045686|negative regulation of glial cell differentiation, ! response to exogenous dsRNA GO:0043330 13 6 1,000 2,948E-04 7,13E-03 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 1,000 2,948E-04 7,06E-03 ! hyperosmotic response GO:0006972 10 6 1,000 2,948E-04 6,992E-03 ! regulation of appetite GO:0032098 10 6 1,000 2,948E-04 6,925E-03 ! interaction with symbiont GO:0051702 14 6 1,000 2,948E-04 6,859E-03 ! positive regulation of cytokine production during immune response GO:0002720 11 6 1,000 2,948E-04 6,794E-03 ! hair follicle maturation GO:0048820 8 6 1,000 2,948E-04 6,73E-03 ! regulation of interleukin-13 production GO:0032656 12 6 1,000 2,948E-04 6,668E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 2,948E-04 6,607E-03 GO:0043011|myeloid dendritic cell differentiation, ! respiratory tube development GO:0030323 171 72 3,000 3,131E-04 6,953E-03 ! regulation of MAPKKK cascade GO:0043408 157 72 3,000 3,131E-04 6,89E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 3,263E-04 7,118E-03 ! complement activation, classical pathway GO:0006958 51 30 2,000 3,263E-04 7,055E-03 ! regulation of coagulation GO:0050818 52 30 2,000 3,263E-04 6,993E-03 ! respiratory system development GO:0060541 175 74 3,000 3,477E-04 7,387E-03 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 2,000 3,961E-04 8,341E-03 ! positive regulation of catabolic process GO:0009896 72 32 2,000 3,961E-04 8,27E-03 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 4,115E-04 8,519E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 4,115E-04 8,448E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,115E-04 8,377E-03 ! regulation of gluconeogenesis GO:0006111 8 7 1,000 4,115E-04 8,308E-03 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 4,115E-04 8,24E-03 ! vesicle fusion GO:0006906 20 7 1,000 4,115E-04 8,173E-03 ! response to dietary excess GO:0002021 8 7 1,000 4,115E-04 8,107E-03 ! male sex determination GO:0030238 15 7 1,000 4,115E-04 8,042E-03 ! fibrinolysis GO:0042730 11 7 1,000 4,115E-04 7,978E-03 ! eating behavior GO:0042755 8 7 1,000 4,115E-04 7,915E-03 ! regulation of interleukin-10 production GO:0032653 13 7 1,000 4,115E-04 7,854E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 4,115E-04 7,793E-03 ! regulation of lipid transport GO:0032368 14 7 1,000 4,115E-04 7,733E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 1,000 4,115E-04 7,674E-03 ! negative regulation of osteoclast differentiation GO:0045671 10 7 1,000 4,115E-04 7,616E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 4,115E-04 7,558E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 4,115E-04 7,502E-03 ! cell fate specification GO:0001708 56 34 2,000 4,747E-04 8,59E-03 ! muscle cell differentiation GO:0042692 178 81 3,000 4,907E-04 8,815E-03 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 4,907E-04 8,751E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 5,141E-04 9,101E-03 ! protein import into nucleus GO:0006606 174 82 3,000 5,141E-04 9,036E-03 ! calcium-mediated signaling GO:0019722 67 35 2,000 5,175E-04 9,031E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 5,383E-04 9,327E-03 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 3,000 5,383E-04 9,261E-03 ! regulation of interferon-alpha production GO:0032647 11 8 1,000 5,47E-04 9,345E-03 ! regulation of response to extracellular stimulus GO:0032104 14 8 1,000 5,47E-04 9,281E-03 GO:0032107|regulation of response to nutrient levels, ! hemoglobin metabolic process GO:0020027 14 8 1,000 5,47E-04 9,217E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 5,47E-04 9,153E-03 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 1,000 5,47E-04 9,091E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 5,47E-04 9,03E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 5,47E-04 8,969E-03 ! regulation of interleukin-4 production GO:0032673 18 8 1,000 5,47E-04 8,909E-03 ! gas homeostasis GO:0033483 14 8 1,000 5,47E-04 8,85E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 5,47E-04 8,792E-03 ! lymph node development GO:0048535 11 8 1,000 5,47E-04 8,735E-03 ! adult feeding behavior GO:0008343 10 8 1,000 5,47E-04 8,678E-03 ! regulation of Rac protein signal transduction GO:0035020 18 8 1,000 5,47E-04 8,622E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 1,000 5,47E-04 8,567E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 5,47E-04 8,512E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 5,47E-04 8,458E-03 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 5,89E-04 9,05E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 6,104E-04 9,319E-03 ! protein localization in nucleus GO:0034504 192 89 3,000 7,005E-04 0,01062978 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 7,013E-04 0,01057519 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 7,013E-04 0,01051032 ! regulation of glycolysis GO:0006110 20 9 1,000 7,013E-04 0,01044623 ! regulation of type I interferon production GO:0032479 12 9 1,000 7,013E-04 0,01038292 ! retinol metabolic process GO:0042572 20 9 1,000 7,013E-04 0,01032037 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 7,013E-04 0,01025857 GO:0002820|negative regulation of adaptive immune response, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 2,000 7,132E-04 0,01037126 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 2,000 7,685E-04 0,0111094 GO:0006956|complement activation, ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 8,265E-04 0,01187701 ! mesenchymal cell development GO:0014031 94 41 2,000 8,265E-04 0,01180756 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of developmental growth GO:0048638 16 10 1,000 8,74E-04 0,01241387 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 8,74E-04 0,01234212 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 8,74E-04 0,01227118 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 8,74E-04 0,01220106 ! glucan biosynthetic process GO:0009250 14 10 1,000 8,74E-04 0,01213174 GO:0005978|glycogen biosynthetic process, ! protein heterooligomerization GO:0051291 17 10 1,000 8,74E-04 0,0120632 ! regulation of gliogenesis GO:0014013 23 10 1,000 8,74E-04 0,01199543 GO:0045685|regulation of glial cell differentiation, ! response to dsRNA GO:0043331 23 10 1,000 8,74E-04 0,01192841 ! spinal cord motor neuron differentiation GO:0021522 19 10 1,000 8,74E-04 0,01186214 ! induction of an organ GO:0001759 17 10 1,000 8,74E-04 0,01179661 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 8,74E-04 0,01173179 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 8,74E-04 0,01166768 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 23 10 1,000 8,74E-04 0,01160427 ! regulation of leukocyte mediated immunity GO:0002703 84 42 2,000 8,871E-04 0,01171516 ! regulation of T cell differentiation GO:0045580 78 42 2,000 8,871E-04 0,01165217 ! regulation of T cell activation GO:0050863 175 96 3,000 9,303E-04 0,01215398 ! positive regulation of transcription factor activity GO:0051091 71 43 2,000 9,506E-04 0,01235235 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 9,506E-04 0,012287 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 1,005E-03 0,01291795 ! energy reserve metabolic process GO:0006112 76 44 2,000 1,017E-03 0,01300536 ! neuron fate specification GO:0048665 18 11 1,000 1,065E-03 0,01355213 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 1,000 1,065E-03 0,01348191 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,065E-03 0,01341241 ! positive regulation of T cell mediated immunity GO:0002711 26 11 1,000 1,065E-03 0,01334363 ! regulation of osteoclast differentiation GO:0045670 17 11 1,000 1,065E-03 0,01327555 ! positive regulation of JNK cascade GO:0046330 23 11 1,000 1,065E-03 0,01320816 ! regulation of embryonic development GO:0045995 35 11 1,000 1,065E-03 0,01314145 ! positive regulation of immune response GO:0050778 175 100 3,000 1,083E-03 0,01329645 ! receptor-mediated endocytosis GO:0006898 98 45 2,000 1,086E-03 0,01326383 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 2,000 1,086E-03 0,01319784 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 2,000 1,158E-03 0,01400287 ! regulation of JNK cascade GO:0046328 104 47 2,000 1,233E-03 0,01483535 ! virus-host interaction GO:0019048 30 12 1,000 1,274E-03 0,015261 ! hippocampus development GO:0021766 29 12 1,000 1,274E-03 0,01518655 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,274E-03 0,01511283 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,274E-03 0,01503982 ! ventral spinal cord development GO:0021517 25 12 1,000 1,274E-03 0,01496752 ! entry into host cell GO:0030260 34 12 1,000 1,274E-03 0,0148959 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 1,000 1,274E-03 0,01482497 ! histone acetylation GO:0016573 27 12 1,000 1,274E-03 0,01475471 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,274E-03 0,01468511 ! T cell homeostasis GO:0043029 28 12 1,000 1,274E-03 0,01461617 ! developmental induction GO:0031128 22 12 1,000 1,274E-03 0,01454787 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 1,274E-03 0,0144802 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,311E-03 0,01482346 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 2,000 1,311E-03 0,01475515 ! positive regulation of DNA binding GO:0043388 83 48 2,000 1,311E-03 0,01468746 ! regulation of adaptive immune response GO:0002819 92 48 2,000 1,311E-03 0,0146204 ! JAK-STAT cascade GO:0007259 82 48 2,000 1,311E-03 0,01455394 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 1,392E-03 0,01538262 ! protein homooligomerization GO:0051260 84 49 2,000 1,392E-03 0,01531333 ! endocrine system development GO:0035270 109 50 2,000 1,476E-03 0,01616483 ! immunoglobulin mediated immune response GO:0016064 89 50 2,000 1,476E-03 0,01609266 GO:0019724|B cell mediated immunity, ! regulation of chemokine production GO:0032642 18 13 1,000 1,502E-03 0,0163044 ! organelle fusion GO:0048284 36 13 1,000 1,502E-03 0,01623226 ! endocrine pancreas development GO:0031018 25 13 1,000 1,502E-03 0,01616075 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 1,000 1,502E-03 0,01608987 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 1,000 1,502E-03 0,01601961 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 1,502E-03 0,01594996 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,502E-03 0,01588091 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cytokine production during immune response GO:0002718 25 13 1,000 1,502E-03 0,01581246 ! gland morphogenesis GO:0022612 31 13 1,000 1,502E-03 0,01574459 ! regulation of steroid biosynthetic process GO:0050810 20 13 1,000 1,502E-03 0,01567731 ! regulation of cell projection organization GO:0031344 135 51 2,000 1,563E-03 0,01624496 ! positive regulation of binding GO:0051099 88 52 2,000 1,653E-03 0,01711054 ! positive regulation of growth GO:0045927 96 53 2,000 1,746E-03 0,01800177 ! chromatin remodeling GO:0006338 122 53 2,000 1,746E-03 0,01792614 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 1,746E-03 0,01785113 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 1,747E-03 0,01778063 GO:0046579|positive regulation of Ras protein signal transduction, ! lipid localization GO:0010876 32 14 1,000 1,747E-03 0,01770685 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 1,000 1,747E-03 0,01763368 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 1,943E-03 0,01953464 ! response to UV GO:0009411 120 55 2,000 1,943E-03 0,01945458 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,01E-03 0,02003847 ! sulfate transport GO:0008272 27 15 1,000 2,01E-03 0,01995702 ! regulation of vasodilation GO:0042312 27 15 1,000 2,01E-03 0,01987622 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,01E-03 0,01979607 ! cell killing GO:0001906 32 15 1,000 2,01E-03 0,01971657 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,01E-03 0,01963771 ! skeletal muscle fiber development GO:0048741 130 56 2,000 2,046E-03 0,01991743 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 2,153E-03 0,02087233 ! muscle fiber development GO:0048747 131 57 2,000 2,153E-03 0,02078983 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 2,29E-03 0,0220249 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 1,000 2,29E-03 0,02193853 ! pituitary gland development GO:0021983 30 16 1,000 2,29E-03 0,02185283 ! response to osmotic stress GO:0006970 27 16 1,000 2,29E-03 0,0217678 ! negative regulation of immune response GO:0050777 38 16 1,000 2,29E-03 0,02168343 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,29E-03 0,02159971 ! regulation of T-helper cell differentiation GO:0045622 30 16 1,000 2,29E-03 0,02151663 ! establishment of organelle localization GO:0051656 122 59 2,000 2,377E-03 0,02224477 ! auditory receptor cell differentiation GO:0042491 36 17 1,000 2,588E-03 0,02412846 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 2,588E-03 0,02403671 ! regulation of survival gene product expression GO:0045884 38 17 1,000 2,588E-03 0,02394566 ! complement activation, alternative pathway GO:0006957 19 17 1,000 2,588E-03 0,0238553 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 1,000 2,588E-03 0,02376562 ! negative regulation of blood coagulation GO:0030195 25 17 1,000 2,588E-03 0,02367661 ! positive regulation of secretion GO:0051047 110 61 2,000 2,614E-03 0,02382761 ! cytokine-mediated signaling pathway GO:0019221 112 61 2,000 2,614E-03 0,02373904 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 2,614E-03 0,02365111 ! viral reproductive process GO:0022415 132 62 2,000 2,738E-03 0,02468145 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 2,903E-03 0,02606996 ! limbic system development GO:0021761 40 18 1,000 2,903E-03 0,02597446 ! positive regulation of proteolysis GO:0045862 36 18 1,000 2,903E-03 0,02587967 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 2,903E-03 0,02578556 ! lymphocyte mediated immunity GO:0002449 122 65 2,000 3,131E-03 0,02771713 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 3,235E-03 0,02852729 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 3,235E-03 0,02842467 ! cell differentiation in spinal cord GO:0021515 37 19 1,000 3,235E-03 0,02832279 ! response to lipopolysaccharide GO:0032496 34 19 1,000 3,235E-03 0,02822164 ! peptide cross-linking GO:0018149 39 19 1,000 3,235E-03 0,02812121 ! regulation of steroid metabolic process GO:0019218 35 19 1,000 3,235E-03 0,02802149 ! visual learning GO:0008542 38 19 1,000 3,235E-03 0,02792247 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 1,000 3,235E-03 0,02782415 ! proximal/distal pattern formation GO:0009954 33 19 1,000 3,235E-03 0,02772652 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 3,27E-03 0,02793063 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 3,27E-03 0,02783331 ! regulation of cellular response to stress GO:0080135 142 68 2,000 3,558E-03 0,03017989 ! positive regulation of T cell activation GO:0050870 124 68 2,000 3,558E-03 0,03007546 ! viral reproduction GO:0016032 142 68 2,000 3,558E-03 0,02997175 ! adaptive immune response GO:0002250 126 68 2,000 3,558E-03 0,02986876 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,583E-03 0,0299807 ! protein amino acid acetylation GO:0006473 41 20 1,000 3,583E-03 0,02987837 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 3,583E-03 0,02977675 ! bile acid metabolic process GO:0008206 34 20 1,000 3,583E-03 0,02967581 ! retinoid metabolic process GO:0001523 34 20 1,000 3,583E-03 0,02957555 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 3,583E-03 0,02947597 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 3,583E-03 0,02937706 ! actin filament bundle formation GO:0051017 47 20 1,000 3,583E-03 0,02927881 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 3,583E-03 0,02918121 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 3,583E-03 0,02908426 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 1,000 3,583E-03 0,02898796 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 3,583E-03 0,02889229 ! negative regulation of coagulation GO:0050819 30 20 1,000 3,583E-03 0,02879725 ! homeostasis of number of cells GO:0048872 131 69 2,000 3,707E-03 0,0296963 ! developmental maturation GO:0021700 128 69 2,000 3,707E-03 0,02959926 ! activation of immune response GO:0002253 120 70 2,000 3,861E-03 0,03072376 ! protein maturation by peptide bond cleavage GO:0051605 118 70 2,000 3,861E-03 0,030624 ! regulation of cell killing GO:0031341 46 21 1,000 3,949E-03 0,03122188 ! lipid phosphorylation GO:0046834 43 21 1,000 3,949E-03 0,03112116 ! regulation of vasoconstriction GO:0019229 40 21 1,000 3,949E-03 0,0310211 ! diencephalon development GO:0021536 36 21 1,000 3,949E-03 0,03092167 ! vitamin A metabolic process GO:0006776 35 21 1,000 3,949E-03 0,03082288 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 4,018E-03 0,03126224 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 4,331E-03 0,03359134 ! inactivation of MAPK activity GO:0000188 45 22 1,000 4,331E-03 0,03348504 ! cellular response to starvation GO:0009267 37 22 1,000 4,331E-03 0,03337941 ! central nervous system neuron development GO:0021954 47 22 1,000 4,331E-03 0,03327444 ! cell aging GO:0007569 48 22 1,000 4,331E-03 0,03317013 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 4,331E-03 0,03306648 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 4,331E-03 0,03296347 ! cytolysis GO:0019835 27 22 1,000 4,331E-03 0,0328611 ! positive regulation of adaptive immune response GO:0002821 42 22 1,000 4,331E-03 0,03275936 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 4,331E-03 0,03265825 ! peptidyl-serine modification GO:0018209 50 22 1,000 4,331E-03 0,03255776 ! terpenoid metabolic process GO:0006721 40 22 1,000 4,331E-03 0,03245789 ! protein stabilization GO:0050821 41 22 1,000 4,331E-03 0,03235863 ! humoral immune response GO:0006959 115 73 2,000 4,344E-03 0,03235639 ! regulation of immune effector process GO:0002697 156 73 2,000 4,344E-03 0,03225804 ! acute inflammatory response GO:0002526 118 74 2,000 4,513E-03 0,03341041 ! regulation of caspase activity GO:0043281 136 74 2,000 4,513E-03 0,03330947 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 4,513E-03 0,03320914 ! organelle localization GO:0051640 155 74 2,000 4,513E-03 0,03310941 ! regulation of transcription factor activity GO:0051090 137 75 2,000 4,686E-03 0,03427416 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 2,000 4,686E-03 0,03417185 ! positive regulation of DNA replication GO:0045740 44 23 1,000 4,73E-03 0,03439025 ! visual behavior GO:0007632 46 23 1,000 4,73E-03 0,0342882 ! regulation of DNA recombination GO:0000018 51 23 1,000 4,73E-03 0,03418676 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 4,73E-03 0,03408591 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 4,73E-03 0,03398566 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 5,043E-03 0,03613159 ! regulation of catabolic process GO:0009894 173 77 2,000 5,043E-03 0,03602594 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 5,145E-03 0,03664356 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 5,145E-03 0,03653704 ! central nervous system neuron differentiation GO:0021953 51 24 1,000 5,145E-03 0,03643113 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 5,145E-03 0,03632584 ! sex determination GO:0007530 48 24 1,000 5,145E-03 0,03622116 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 1,000 5,145E-03 0,03611707 GO:0002708|positive regulation of lymphocyte mediated immunity, ! membrane depolarization GO:0051899 45 24 1,000 5,145E-03 0,03601359 ! pallium development GO:0021543 56 24 1,000 5,145E-03 0,03591069 ! detection of biotic stimulus GO:0009595 34 24 1,000 5,145E-03 0,03580838 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 5,145E-03 0,03570665 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 5,228E-03 0,03618176 ! blood coagulation GO:0007596 151 79 2,000 5,417E-03 0,03738218 GO:0050817|coagulation, ! protein import into nucleus, translocation GO:0000060 51 25 1,000 5,576E-03 0,03837114 ! regulation of transmembrane transport GO:0034762 39 25 1,000 5,576E-03 0,03826335 ! vasculogenesis GO:0001570 49 25 1,000 5,576E-03 0,03815617 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 5,576E-03 0,03804959 ! leukocyte homeostasis GO:0001776 50 25 1,000 5,576E-03 0,0379436 ! liver development GO:0001889 55 25 1,000 5,576E-03 0,03783821 ! protein tetramerization GO:0051262 57 25 1,000 5,576E-03 0,03773339 ! initiation of viral infection GO:0019059 60 26 1,000 6,023E-03 0,04064584 ! molting cycle process GO:0022404 52 26 1,000 6,023E-03 0,04053387 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 6,023E-03 0,04042251 ! spinal cord development GO:0021510 54 26 1,000 6,023E-03 0,04031176 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 6,023E-03 0,04020162 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 6,023E-03 0,04009208 ! negative regulation of cell development GO:0010721 83 26 1,000 6,023E-03 0,03998314 GO:0050768|negative regulation of neurogenesis, ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 6,023E-03 0,03987478 ! T cell activation GO:0042110 189 84 2,000 6,422E-03 0,04240132 ! regulation of interferon-gamma production GO:0032649 43 27 1,000 6,486E-03 0,04270753 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 6,486E-03 0,04259273 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 6,486E-03 0,04247854 ! response to starvation GO:0042594 47 27 1,000 6,486E-03 0,04236496 ! cellular response to nutrient levels GO:0031669 45 27 1,000 6,486E-03 0,04225199 ! fat-soluble vitamin metabolic process GO:0006775 42 27 1,000 6,486E-03 0,04213961 ! hemostasis GO:0007599 165 85 2,000 6,635E-03 0,04299684 ! regulation of neuron differentiation GO:0045664 187 85 2,000 6,635E-03 0,0428831 ! positive regulation of cell activation GO:0050867 161 86 2,000 6,853E-03 0,04417242 GO:0002696|positive regulation of leukocyte activation, ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 6,964E-03 0,04477235 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 6,964E-03 0,04465484 ! protein amino acid acylation GO:0043543 59 28 1,000 6,964E-03 0,04453794 ! vesicle docking GO:0048278 55 28 1,000 6,964E-03 0,04442166 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 6,964E-03 0,04430597 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 6,964E-03 0,04419089 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 7,458E-03 0,04720319 ! somitogenesis GO:0001756 52 29 1,000 7,458E-03 0,04708122 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 7,458E-03 0,04695987 ! regulation of DNA binding GO:0051101 167 89 2,000 7,531E-03 0,04729488 ! positive regulation of protein modification process GO:0031401 156 90 2,000 7,765E-03 0,04864248 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 1,000 7,968E-03 0,04978247 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 7,968E-03 0,04965547 ! cell fate determination GO:0001709 64 30 1,000 7,968E-03 0,04952912 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 7,968E-03 0,04940342 ! gland development GO:0048732 220 91 2,000 8,004E-03 0,04950346 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 8,492E-03 0,05239062 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 8,492E-03 0,05225865 ! response to heat GO:0009408 54 31 1,000 8,492E-03 0,05212735 ! positive regulation of immune effector process GO:0002699 78 31 1,000 8,492E-03 0,0519967 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 8,494E-03 0,0518799 ! vitamin metabolic process GO:0006766 153 93 2,000 8,494E-03 0,05175052 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 9,002E-03 0,05470723 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 9,032E-03 0,05475258 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 9,032E-03 0,05461706 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 9,032E-03 0,0544822 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 9,032E-03 0,05434801 ! myeloid leukocyte activation GO:0002274 53 32 1,000 9,032E-03 0,05421448 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 9,527E-03 0,05704708 ! negative regulation of response to external stimulus GO:0032102 50 33 1,000 9,587E-03 0,05726263 ! cholesterol homeostasis GO:0042632 60 33 1,000 9,587E-03 0,05712297 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 9,587E-03 0,05698398 ! cholesterol transport GO:0030301 62 34 1,000 0,01015625 0,0602226 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01015625 0,06007678 ! hormone metabolic process GO:0042445 171 100 2,000 0,01034792 0,06106273 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01074041 0,06322609 ! membrane docking GO:0022406 69 35 1,000 0,01074041 0,06307411 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,01074041 0,06292285 ! telencephalon development GO:0021537 81 35 1,000 0,01074041 0,06277232 ! sterol transport GO:0015918 63 35 1,000 0,01074041 0,0626225 ! placenta development GO:0001890 53 35 1,000 0,01074041 0,0624734 ! regulation of proteolysis GO:0030162 77 36 1,000 0,0113391 0,06579911 ! cytokine production GO:0001816 68 36 1,000 0,0113391 0,06564319 ! tissue remodeling GO:0048771 78 37 1,000 0,01195217 0,06902874 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01195217 0,06886594 ! actomyosin structure organization GO:0031032 68 37 1,000 0,01195217 0,0687039 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01257949 0,07214011 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,01257949 0,07197117 GO:0006639|acylglycerol metabolic process, ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,01257949 0,07180301 ! regulation of protein stability GO:0031647 77 38 1,000 0,01257949 0,07163564 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01257949 0,07146904 ! isoprenoid metabolic process GO:0006720 70 39 1,000 0,01322091 0,07493893 ! glucan metabolic process GO:0044042 64 39 1,000 0,01322091 0,07476546 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,0138763 0,07829052 ! learning GO:0007612 82 40 1,000 0,0138763 0,07811012 ! lipid homeostasis GO:0055088 75 40 1,000 0,0138763 0,07793056 ! glycerol ether metabolic process GO:0006662 57 40 1,000 0,0138763 0,07775182 ! Rho protein signal transduction GO:0007266 88 40 1,000 0,0138763 0,0775739 ! feeding behavior GO:0007631 69 41 1,000 0,01454552 0,08112945 ! organic ether metabolic process GO:0018904 59 42 1,000 0,01522844 0,08474504 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01522844 0,08455243 ! T cell differentiation GO:0030217 93 42 1,000 0,01522844 0,0843607 ! cytokinesis GO:0000910 84 42 1,000 0,01522844 0,08416984 ! glucose transport GO:0015758 66 43 1,000 0,01592492 0,08782071 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,01592492 0,08762292 ! segmentation GO:0035282 78 43 1,000 0,01592492 0,08742601 ! hexose transport GO:0008645 68 44 1,000 0,01663483 0,09111858 GO:0015749|monosaccharide transport, ! keratinocyte differentiation GO:0030216 81 45 1,000 0,01735804 0,0948673 ! developmental growth GO:0048589 88 45 1,000 0,01735804 0,09465554 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01809441 0,09845132 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01809441 0,09823254 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,01809441 0,09801473 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01809441 0,09779788 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,01960613 0,1057346 ! activation of caspase activity GO:0006919 95 50 1,000 0,02116895 0,11391136 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,02116895 0,113661 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,02116895 0,11341174 ! viral infectious cycle GO:0019058 104 51 1,000 0,02196921 0,11744154 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02196921 0,11718512 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02196921 0,11692981 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02216867 0,1177349 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02216867 0,11747951 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02216867 0,11722522 GO:0045844|positive regulation of striated muscle development, ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02216867 0,11697204 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02216867 0,11671994 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02216867 0,11646893 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02216867 0,116219 ! polyol transport GO:0015791 12 5 0,000 0,02216867 0,11597014 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02216867 0,11572234 ! response to superoxide GO:0000303 10 5 0,000 0,02216867 0,11547559 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02216867 0,1152299 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02216867 0,11498525 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02216867 0,11474164 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02216867 0,11449906 ! female meiosis GO:0007143 10 5 0,000 0,02216867 0,1142575 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02216867 0,11401695 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02216867 0,11377742 ! hypothalamus development GO:0021854 9 5 0,000 0,02216867 0,1135389 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02216867 0,11330137 ! cobalt ion transport GO:0006824 11 5 0,000 0,02216867 0,11306483 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02216867 0,11282928 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02216867 0,11259471 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02216867 0,11236111 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02216867 0,11212847 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02216867 0,1118968 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02216867 0,11166609 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02216867 0,11143632 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02216867 0,1112075 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02216867 0,11097962 ! transposition GO:0032196 9 5 0,000 0,02216867 0,11075266 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02216867 0,11052664 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02216867 0,11030153 ! negative chemotaxis GO:0050919 16 5 0,000 0,02216867 0,11007734 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02216867 0,10985406 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02216867 0,10963169 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02216867 0,10941021 ! behavioral response to pain GO:0048266 10 5 0,000 0,02216867 0,10918962 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02216867 0,10896993 ! Notch receptor processing GO:0007220 11 5 0,000 0,02216867 0,10875111 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02216867 0,10853317 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02216867 0,10831611 ! micturition GO:0060073 9 5 0,000 0,02216867 0,10809991 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02216867 0,10788457 ! copulation GO:0007620 9 5 0,000 0,02216867 0,10767009 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02216867 0,10745645 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02216867 0,10724367 ! bioluminescence GO:0008218 9 5 0,000 0,02216867 0,10703173 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02216867 0,10682062 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02216867 0,10661034 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02216867 0,10640089 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02216867 0,10619226 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02216867 0,10598445 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02216867 0,10577745 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02216867 0,10557125 ! grooming behavior GO:0007625 6 5 0,000 0,02216867 0,10536586 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02216867 0,10516127 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02216867 0,10495747 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02216867 0,10475445 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02216867 0,10455223 ! response to protozoan GO:0001562 13 5 0,000 0,02216867 0,10435078 ! lymph vessel development GO:0001945 10 5 0,000 0,02216867 0,1041501 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02216867 0,1039502 ! endochondral ossification GO:0001958 17 5 0,000 0,02216867 0,10375106 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02216867 0,10355268 ! single strand break repair GO:0000012 8 5 0,000 0,02216867 0,10335506 ! parathyroid gland development GO:0060017 14 5 0,000 0,02216867 0,1031582 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02216867 0,10296208 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02216867 0,1027667 ! cytokine secretion GO:0050663 15 5 0,000 0,02216867 0,10257207 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02216867 0,10237817 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02216867 0,10218501 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02216867 0,10199257 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02216867 0,10180085 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02216867 0,10160986 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02216867 0,10141958 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02216867 0,10123001 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02216867 0,10104114 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02216867 0,10085299 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02216867 0,10066553 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02216867 0,10047876 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02216867 0,10029269 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02216867 0,10010731 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02216867 0,09992261 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02216867 0,09973859 ! valine metabolic process GO:0006573 12 5 0,000 0,02216867 0,09955524 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02216867 0,09937257 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02216867 0,09919057 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02216867 0,09900924 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02216867 0,09882856 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02216867 0,09864855 ! polyol catabolic process GO:0046174 9 5 0,000 0,02216867 0,09846919 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02216867 0,09829048 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02216867 0,09811242 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02216867 0,097935 ! mitochondrial fission GO:0000266 8 5 0,000 0,02216867 0,09775822 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02216867 0,09758208 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02216867 0,09740657 ! mRNA transcription GO:0009299 10 5 0,000 0,02216867 0,09723169 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02216867 0,09705744 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02216867 0,09688382 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02216867 0,09671081 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02216867 0,09653842 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02216867 0,09636664 ! monocyte activation GO:0042117 10 5 0,000 0,02216867 0,09619548 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02216867 0,09602492 GO:0060177|regulation of angiotensin metabolic process, ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02216867 0,09585496 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02216867 0,09568561 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02216867 0,09551685 ! forebrain neuron development GO:0021884 13 5 0,000 0,02216867 0,09534869 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02216867 0,09518111 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02216867 0,09501413 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02216867 0,09484773 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02216867 0,09468191 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02216867 0,09451667 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02216867 0,09435201 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02216867 0,09418792 ! lipid glycosylation GO:0030259 7 5 0,000 0,02216867 0,0940244 ! nucleobase transport GO:0015851 6 5 0,000 0,02216867 0,09386144 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02216867 0,09369905 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02216867 0,09353722 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02216867 0,09337595 ! basic amino acid transport GO:0015802 12 5 0,000 0,02216867 0,09321524 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02216867 0,09305507 ! actin nucleation GO:0045010 11 5 0,000 0,02216867 0,09289546 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02216867 0,09273639 ! depurination GO:0045007 5 5 0,000 0,02216867 0,09257787 ! depyrimidination GO:0045008 10 5 0,000 0,02216867 0,09241989 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02216867 0,09226244 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02216867 0,09210553 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02216867 0,09194916 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02216867 0,09179331 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02216867 0,09163799 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02216867 0,0914832 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02216867 0,09132893 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02216867 0,09117517 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02216867 0,09102194 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02216867 0,09086922 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02216867 0,09071701 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02216867 0,09056531 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02216867 0,09041411 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02216867 0,09026342 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02216867 0,09011323 ! response to arsenic GO:0046685 11 5 0,000 0,02216867 0,08996354 ! mast cell degranulation GO:0043303 7 5 0,000 0,02216867 0,08981435 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02216867 0,08966565 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02216867 0,08951744 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02216867 0,08936972 ! response to mercury ion GO:0046689 8 5 0,000 0,02216867 0,08922249 ! response to cadmium ion GO:0046686 7 5 0,000 0,02216867 0,08907575 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02216867 0,08892948 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02216867 0,08878369 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02216867 0,08863838 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02216867 0,08849355 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02216867 0,08834919 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02216867 0,0882053 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02216867 0,08806188 ! decidualization GO:0046697 11 5 0,000 0,02216867 0,08791892 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02216867 0,08777642 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02216867 0,08763439 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02216867 0,08749282 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02216867 0,0873517 ! embryonic cleavage GO:0040016 6 5 0,000 0,02216867 0,08721104 ! peroxisome fission GO:0016559 5 5 0,000 0,02216867 0,08707082 ! histone demethylation GO:0016577 13 5 0,000 0,02216867 0,08693106 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02216867 0,08679175 ! mitotic recombination GO:0006312 9 5 0,000 0,02216867 0,08665289 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02216867 0,08651446 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02216867 0,08637648 ! metaphase plate congression GO:0051310 7 5 0,000 0,02216867 0,08623894 ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02216867 0,08610183 ! enteric nervous system development GO:0048484 8 5 0,000 0,02216867 0,08596516 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02216867 0,08582893 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02216867 0,08569312 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02216867 0,08555775 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02216867 0,0854228 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02216867 0,08528827 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02216867 0,08515417 ! B cell homeostasis GO:0001782 13 5 0,000 0,02216867 0,08502049 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02216867 0,08488723 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02216867 0,08475439 ! metaphase GO:0051323 11 5 0,000 0,02216867 0,08462196 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02216867 0,08448994 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02216867 0,08435834 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02216867 0,08422714 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02216867 0,08409636 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02216867 0,08396597 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02216867 0,083836 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02216867 0,08370642 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02216867 0,08357724 ! response to redox state GO:0051775 6 5 0,000 0,02216867 0,08344846 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02216867 0,08332008 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02216867 0,08319209 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02216867 0,0830645 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02216867 0,08293729 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02216867 0,08281048 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02216867 0,08268405 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02216867 0,08255801 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02216867 0,08243235 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02216867 0,08230707 ! striatum development GO:0021756 14 5 0,000 0,02216867 0,08218217 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02216867 0,08205766 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02216867 0,08193351 ! glial cell migration GO:0008347 10 5 0,000 0,02216867 0,08180975 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02216867 0,08168635 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02216867 0,08156333 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02216867 0,08144068 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02216867 0,0813184 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02216867 0,08119648 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02216867 0,08107493 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02216867 0,08095374 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02216867 0,08083292 ! neuroprotection GO:0043526 8 5 0,000 0,02216867 0,08071245 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02216867 0,08059234 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02216867 0,08047259 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02216867 0,08035319 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02216867 0,08023415 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02216867 0,08011546 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02216867 0,07999712 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02216867 0,07987913 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02216867 0,07976149 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02216867 0,0796442 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02216867 0,07952724 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02216867 0,07941064 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02216867 0,07929437 ! spindle assembly GO:0051225 6 5 0,000 0,02216867 0,07917844 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02216867 0,07906285 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02216867 0,0789476 ! protein palmitoylation GO:0018345 12 5 0,000 0,02216867 0,07883268 ! drug metabolic process GO:0017144 7 5 0,000 0,02216867 0,0787181 ! stem cell division GO:0017145 11 5 0,000 0,02216867 0,07860385 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02216867 0,07848993 ! organ regeneration GO:0031100 7 5 0,000 0,02216867 0,07837634 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02216867 0,07826308 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02216867 0,07815015 ! excretion GO:0007588 87 52 1,000 0,02278186 0,0801961 ! histone modification GO:0016570 104 52 1,000 0,02278186 0,08008071 ! vesicle organization GO:0016050 127 53 1,000 0,02360678 0,08286117 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,02360678 0,08274228 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,02444385 0,08555347 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,02444385 0,08543108 ! regulation of muscle contraction GO:0006937 94 54 1,000 0,02444385 0,08530903 ! membrane fusion GO:0006944 122 54 1,000 0,02444385 0,08518734 ! covalent chromatin modification GO:0016569 115 54 1,000 0,02444385 0,08506599 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02529293 0,08789565 ! cell maturation GO:0048469 107 55 1,000 0,02529293 0,0877708 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,02529293 0,0876463 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,02529293 0,08752215 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,02615392 0,09037344 ! regulation of DNA replication GO:0006275 105 56 1,000 0,02615392 0,0902458 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02654344 0,09146069 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02654344 0,09133188 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02654344 0,09120342 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02654344 0,09107533 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02654344 0,09094759 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02654344 0,09082021 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02654344 0,09069319 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02654344 0,09056653 ! response to oxygen radical GO:0000305 11 6 0,000 0,02654344 0,09044021 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02654344 0,09031425 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02654344 0,09018864 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02654344 0,09006338 ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02654344 0,08993846 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02654344 0,08981389 ! forebrain regionalization GO:0021871 9 6 0,000 0,02654344 0,08968967 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02654344 0,08956579 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02654344 0,08944225 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02654344 0,08931905 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02654344 0,08919619 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02654344 0,08907367 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02654344 0,08895148 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02654344 0,08882963 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02654344 0,08870812 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02654344 0,08858693 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02654344 0,08846607 ! malate metabolic process GO:0006108 13 6 0,000 0,02654344 0,08834555 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02654344 0,08822535 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02654344 0,08810548 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02654344 0,08798593 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02654344 0,08786671 ! protein refolding GO:0042026 15 6 0,000 0,02654344 0,08774781 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02654344 0,08762923 ! opsonization GO:0008228 8 6 0,000 0,02654344 0,08751097 ! mating behavior GO:0007617 7 6 0,000 0,02654344 0,08739304 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02654344 0,08727541 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02654344 0,08715811 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02654344 0,08704112 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02654344 0,08692444 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02654344 0,08680808 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02654344 0,08669202 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02654344 0,08657628 ! toxin metabolic process GO:0009404 11 6 0,000 0,02654344 0,08646084 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02654344 0,08634572 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02654344 0,08623089 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02654344 0,08611638 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02654344 0,08600216 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02654344 0,08588825 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02654344 0,08577465 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02654344 0,08566134 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02654344 0,08554833 ! thymic T cell selection GO:0045061 16 6 0,000 0,02654344 0,08543562 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02654344 0,0853232 ! protein lipoylation GO:0009249 10 6 0,000 0,02654344 0,08521108 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02654344 0,08509925 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02654344 0,08498772 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02654344 0,08487648 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02654344 0,08476553 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02654344 0,08465487 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02654344 0,0845445 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02654344 0,08443442 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02654344 0,08432462 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02654344 0,08421511 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02654344 0,08410588 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02654344 0,08399693 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02654344 0,08388827 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02654344 0,08377989 ! urea metabolic process GO:0019627 7 6 0,000 0,02654344 0,08367178 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02654344 0,08356396 ! neutrophil activation GO:0042119 7 6 0,000 0,02654344 0,08345641 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02654344 0,08334914 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02654344 0,08324215 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02654344 0,08313543 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02654344 0,08302898 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02654344 0,0829228 ! neuron apoptosis GO:0051402 15 6 0,000 0,02654344 0,0828169 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02654344 0,08271127 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02654344 0,0826059 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02654344 0,0825008 ! carnitine transport GO:0015879 10 6 0,000 0,02654344 0,08239597 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02654344 0,08229141 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02654344 0,08218711 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02654344 0,08208308 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02654344 0,08197931 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02654344 0,0818758 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02654344 0,08177255 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02654344 0,08166956 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02654344 0,08156683 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02654344 0,08146436 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02654344 0,08136215 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02654344 0,08126019 ! neural nucleus development GO:0048857 19 6 0,000 0,02654344 0,08115849 ! response to UV-C GO:0010225 14 6 0,000 0,02654344 0,08105704 ! astrocyte development GO:0014002 16 6 0,000 0,02654344 0,08095585 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02654344 0,0808549 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02654344 0,08075421 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02654344 0,08065377 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02654344 0,08055358 ! response to copper ion GO:0046688 10 6 0,000 0,02654344 0,08045364 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02654344 0,08035394 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02654344 0,0802545 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02654344 0,08015529 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02654344 0,08005634 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02654344 0,07995762 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02654344 0,07985915 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02654344 0,07976093 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02654344 0,07966294 ! Schwann cell development GO:0014044 15 6 0,000 0,02654344 0,07956519 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02654344 0,07946769 ! response to pheromone GO:0019236 6 6 0,000 0,02654344 0,07937042 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02654344 0,07927339 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02654344 0,0791766 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02654344 0,07908004 ! subpallium development GO:0021544 15 6 0,000 0,02654344 0,07898372 ! neural tube patterning GO:0021532 8 6 0,000 0,02654344 0,07888763 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02654344 0,07879178 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02654344 0,07869616 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02654344 0,07860077 ! G2 phase GO:0051319 16 6 0,000 0,02654344 0,07850561 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02654344 0,07841068 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02654344 0,07831598 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02654344 0,07822151 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02654344 0,07812727 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02654344 0,07803325 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02654344 0,07793946 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02654344 0,0778459 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02654344 0,07775256 ! receptor internalization GO:0031623 11 6 0,000 0,02654344 0,07765944 ! plasminogen activation GO:0031639 9 6 0,000 0,02654344 0,07756655 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02654344 0,07747387 ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02654344 0,07738142 ! protein deubiquitination GO:0016579 16 6 0,000 0,02654344 0,07728919 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02654344 0,07719718 ! protein destabilization GO:0031648 9 6 0,000 0,02654344 0,07710539 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02654344 0,07701381 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02654344 0,07692246 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02654344 0,07683132 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02654344 0,07674039 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02654344 0,07664968 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02654344 0,07655919 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02654344 0,07646891 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02654344 0,07637884 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02654344 0,07628898 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02654344 0,07619933 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02654344 0,0761099 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02654344 0,07602067 ! neural plate development GO:0001840 9 6 0,000 0,02654344 0,07593165 ! catecholamine transport GO:0051937 9 6 0,000 0,02654344 0,07584284 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02654344 0,07575424 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02654344 0,07566585 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02654344 0,07557766 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02654344 0,07548968 ! maternal placenta development GO:0001893 12 6 0,000 0,02654344 0,0754019 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02654344 0,07531432 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02654344 0,07522695 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02654344 0,07513978 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02654344 0,07505281 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02654344 0,07496605 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02654344 0,07487948 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02654344 0,07479312 GO:0055081|anion homeostasis, ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,02702668 0,07606702 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,02702668 0,07597949 ! heart morphogenesis GO:0003007 105 57 1,000 0,02702668 0,07589216 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,02702668 0,07580502 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,02791109 0,07819587 ! aging GO:0007568 112 58 1,000 0,02791109 0,0781063 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,02791109 0,07801694 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,02791109 0,07792777 ! lipid modification GO:0030258 112 60 1,000 0,02971441 0,08286792 ! regulation of endocytosis GO:0030100 104 60 1,000 0,02971441 0,08277343 ! adult behavior GO:0030534 104 60 1,000 0,02971441 0,08267915 ! tRNA transcription GO:0009304 17 7 0,000 0,03089877 0,08587679 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03089877 0,0857792 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03089877 0,08568183 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03089877 0,08558469 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03089877 0,08548776 ! sleep GO:0030431 16 7 0,000 0,03089877 0,08539106 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03089877 0,08529457 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03089877 0,0851983 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03089877 0,08510225 ! prostate gland development GO:0030850 14 7 0,000 0,03089877 0,08500641 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03089877 0,08491079 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03089877 0,08481539 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03089877 0,0847202 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03089877 0,08462522 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03089877 0,08453045 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03089877 0,0844359 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03089877 0,08434156 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03089877 0,08424743 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03089877 0,08415351 ! glycolipid transport GO:0046836 11 7 0,000 0,03089877 0,08405979 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03089877 0,08396629 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03089877 0,08387299 ! neuron adhesion GO:0007158 14 7 0,000 0,03089877 0,08377991 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03089877 0,08368702 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03089877 0,08359435 ! mRNA stabilization GO:0048255 18 7 0,000 0,03089877 0,08350187 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03089877 0,08340961 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03089877 0,08331754 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03089877 0,08322568 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03089877 0,08313403 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03089877 0,08304257 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03089877 0,08295131 ! lipoprotein transport GO:0042953 14 7 0,000 0,03089877 0,08286026 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03089877 0,0827694 ! rhythmic behavior GO:0007622 17 7 0,000 0,03089877 0,08267875 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03089877 0,08258829 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03089877 0,08249803 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03089877 0,08240796 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03089877 0,0823181 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03089877 0,08222843 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03089877 0,08213895 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03089877 0,08204967 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03089877 0,08196058 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03089877 0,08187169 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03089877 0,08178298 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03089877 0,08169447 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03089877 0,08160616 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03089877 0,08151803 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03089877 0,08143009 ! spinal cord patterning GO:0021511 14 7 0,000 0,03089877 0,08134234 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03089877 0,08125478 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03089877 0,08116741 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03089877 0,08108023 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03089877 0,08099323 ! adrenal gland development GO:0030325 17 7 0,000 0,03089877 0,08090643 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03089877 0,0808198 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03089877 0,08073336 ! ovulation GO:0030728 10 7 0,000 0,03089877 0,08064711 ! adenohypophysis development GO:0021984 11 7 0,000 0,03089877 0,08056104 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03089877 0,08047515 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03089877 0,08038945 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03089877 0,08030393 ! microtubule nucleation GO:0007020 21 7 0,000 0,03089877 0,08021859 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03089877 0,08013343 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03089877 0,08004846 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03089877 0,07996366 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03089877 0,07987904 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03089877 0,0797946 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03089877 0,07971034 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03089877 0,07962626 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03089877 0,07954235 ! galactose metabolic process GO:0006012 13 7 0,000 0,03089877 0,07945863 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03089877 0,07937507 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03089877 0,0792917 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03089877 0,07920849 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03089877 0,07912547 ! organ growth GO:0035265 15 7 0,000 0,03089877 0,07904261 ! nucleoside transport GO:0015858 11 7 0,000 0,03089877 0,07895993 ! nucleoside salvage GO:0043174 11 7 0,000 0,03089877 0,07887742 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03089877 0,07879509 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03089877 0,07871292 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03089877 0,07863093 ! parturition GO:0007567 16 7 0,000 0,03089877 0,07854911 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03089877 0,07846746 ! rRNA modification GO:0000154 14 7 0,000 0,03089877 0,07838598 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03089877 0,07830466 ! spindle checkpoint GO:0031577 16 7 0,000 0,03089877 0,07822352 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03089877 0,07814254 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03089877 0,07806173 ! monocyte differentiation GO:0030224 16 7 0,000 0,03089877 0,07798109 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03089877 0,07790061 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03089877 0,0778203 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03089877 0,07774016 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03089877 0,07766018 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03089877 0,07758036 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03089877 0,07750071 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03089877 0,07742123 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03089877 0,0773419 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03089877 0,07726274 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03089877 0,07718374 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03089877 0,0771049 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03089877 0,07702622 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03089877 0,0769477 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03089877 0,07686934 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03089877 0,07679114 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03089877 0,0767131 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03089877 0,07663522 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03089877 0,0765575 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03089877 0,07647993 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03089877 0,07640253 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03089877 0,07632527 ! histone ubiquitination GO:0016574 9 7 0,000 0,03089877 0,07624818 ! regulation of meiosis GO:0040020 12 7 0,000 0,03089877 0,07617124 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03089877 0,07609445 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03089877 0,07601782 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03089877 0,07594134 GO:0002714|positive regulation of B cell mediated immunity, ! membrane to membrane docking GO:0022614 14 7 0,000 0,03089877 0,07586502 ! transcription termination GO:0006353 14 7 0,000 0,03089877 0,07578885 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03089877 0,07571283 ! anaphase GO:0051322 18 7 0,000 0,03089877 0,07563697 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03089877 0,07556126 ! axonal fasciculation GO:0007413 19 7 0,000 0,03089877 0,07548569 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03089877 0,07541028 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03089877 0,07533502 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03089877 0,07525991 ! diuresis GO:0030146 12 7 0,000 0,03089877 0,07518495 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03089877 0,07511014 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03089877 0,07503548 ! antibiotic transport GO:0042891 9 7 0,000 0,03089877 0,07496097 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03089877 0,0748866 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03089877 0,07481238 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03089877 0,07473831 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03089877 0,07466439 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03089877 0,07459061 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03089877 0,07451697 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03089877 0,07444349 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03089877 0,07437014 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03089877 0,07429694 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03089877 0,07422389 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03089877 0,07415098 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03089877 0,07407821 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03089877 0,07400558 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03089877 0,0739331 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03089877 0,07386076 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03089877 0,07378856 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03089877 0,0737165 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03089877 0,07364458 ! muscle adaptation GO:0043500 13 7 0,000 0,03089877 0,0735728 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03089877 0,07350116 ! retina homeostasis GO:0001895 12 7 0,000 0,03089877 0,07342966 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03089877 0,0733583 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03089877 0,07328708 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03089877 0,073216 ! regulation of mitosis GO:0007088 112 63 1,000 0,03250381 0,07694458 GO:0051783|regulation of nuclear division, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03523473 0,08332861 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03523473 0,08324802 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03523473 0,08316759 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03523473 0,08308731 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03523473 0,08300719 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03523473 0,08292722 ! male meiosis GO:0007140 9 8 0,000 0,03523473 0,0828474 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03523473 0,08276774 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03523473 0,08268823 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03523473 0,08260888 ! meiotic prophase I GO:0007128 14 8 0,000 0,03523473 0,08252967 ! response to zinc ion GO:0010043 12 8 0,000 0,03523473 0,08245062 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03523473 0,08237172 ! oligopeptide transport GO:0006857 16 8 0,000 0,03523473 0,08229297 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03523473 0,08221438 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03523473 0,08213593 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03523473 0,08205763 ! signal peptide processing GO:0006465 12 8 0,000 0,03523473 0,08197948 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03523473 0,08190148 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03523473 0,08182362 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03523473 0,08174592 ! succinate metabolic process GO:0006105 17 8 0,000 0,03523473 0,08166836 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03523473 0,08159095 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03523473 0,08151368 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03523473 0,08143657 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03523473 0,08135959 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03523473 0,08128277 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03523473 0,08120609 ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03523473 0,08112955 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03523473 0,08105316 ! reflex GO:0060004 17 8 0,000 0,03523473 0,08097691 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03523473 0,0809008 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03523473 0,08082484 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03523473 0,08074902 ! pigment granule organization GO:0048753 17 8 0,000 0,03523473 0,08067334 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03523473 0,0805978 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03523473 0,0805224 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03523473 0,08044715 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03523473 0,08037204 ! histidine catabolic process GO:0006548 10 8 0,000 0,03523473 0,08029706 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03523473 0,08022223 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03523473 0,08014753 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03523473 0,08007298 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,03523473 0,07999856 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03523473 0,07992428 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03523473 0,07985014 ! melanin metabolic process GO:0006582 17 8 0,000 0,03523473 0,07977614 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03523473 0,07970227 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03523473 0,07962854 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03523473 0,07955495 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03523473 0,07948149 ! macrophage activation GO:0042116 13 8 0,000 0,03523473 0,07940816 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03523473 0,07933498 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03523473 0,07926193 ! purine salvage GO:0043101 12 8 0,000 0,03523473 0,07918901 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03523473 0,07911622 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03523473 0,07904357 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03523473 0,07897106 ! osteoblast development GO:0002076 17 8 0,000 0,03523473 0,07889867 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03523473 0,07882642 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03523473 0,0787543 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03523473 0,07868231 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03523473 0,07861046 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03523473 0,07853873 ! response to UV-B GO:0010224 17 8 0,000 0,03523473 0,07846714 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03523473 0,07839567 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03523473 0,07832434 ! intermediate filament organization GO:0045109 12 8 0,000 0,03523473 0,07825314 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03523473 0,07818206 ! cellular extravasation GO:0045123 13 8 0,000 0,03523473 0,07811112 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03523473 0,0780403 ! response to antibiotic GO:0046677 11 8 0,000 0,03523473 0,07796961 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03523473 0,07789905 ! DNA topological change GO:0006265 12 8 0,000 0,03523473 0,07782862 ! response to tropane GO:0014073 15 8 0,000 0,03523473 0,07775831 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03523473 0,07768813 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03523473 0,07761808 ! mast cell activation GO:0045576 14 8 0,000 0,03523473 0,07754815 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03523473 0,07747835 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03523473 0,07740868 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03523473 0,07733913 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03523473 0,0772697 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03523473 0,0772004 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03523473 0,07713123 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03523473 0,07706218 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03523473 0,07699325 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03523473 0,07692444 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03523473 0,07685576 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03523473 0,0767872 ! response to tumor cell GO:0002347 16 8 0,000 0,03523473 0,07671876 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03523473 0,07665045 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03523473 0,07658225 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03523473 0,07651418 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03523473 0,07644623 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03523473 0,07637839 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03523473 0,07631068 ! hormone catabolic process GO:0042447 17 8 0,000 0,03523473 0,07624309 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03523473 0,07617562 GO:0046479|glycosphingolipid catabolic process, ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03523473 0,07610827 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03523473 0,07604103 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03523473 0,07597392 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03523473 0,07590692 ! ATP catabolic process GO:0006200 11 8 0,000 0,03523473 0,07584004 ! blastocyst growth GO:0001832 19 8 0,000 0,03523473 0,07577328 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03523473 0,07570664 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03523473 0,07564011 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03523473 0,07557371 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03523473 0,07550741 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03523473 0,07544124 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03523473 0,07537518 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03523473 0,07530923 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03523473 0,0752434 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03523473 0,07517769 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03523473 0,07511209 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03523473 0,0750466 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03523473 0,07498123 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03523473 0,07491597 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03523473 0,07485083 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03523473 0,0747858 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03523473 0,07472088 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03523473 0,07465607 ! activation of MAPK activity GO:0000187 124 67 1,000 0,03637571 0,07700682 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,03637571 0,07694014 GO:0035113|embryonic appendage morphogenesis, ! secondary metabolic process GO:0019748 125 67 1,000 0,03637571 0,07687359 ! detection of external stimulus GO:0009581 102 68 1,000 0,03737019 0,07890699 ! regulation of lipase activity GO:0060191 137 68 1,000 0,03737019 0,07883885 ! negative regulation of cell size GO:0045792 144 69 1,000 0,03837505 0,08088891 ! cellular hormone metabolic process GO:0034754 120 69 1,000 0,03837505 0,08081918 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,03837505 0,08074957 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,03939017 0,08281428 ! germ cell development GO:0007281 133 70 1,000 0,03939017 0,08274307 ! axon extension GO:0048675 16 9 0,000 0,03955142 0,0830104 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03955142 0,08293915 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03955142 0,08286802 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03955142 0,08279701 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03955142 0,08272612 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03955142 0,08265535 ! reproductive behavior GO:0019098 22 9 0,000 0,03955142 0,08258471 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03955142 0,08251418 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03955142 0,08244378 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03955142 0,08237349 ! UTP metabolic process GO:0046051 10 9 0,000 0,03955142 0,08230333 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03955142 0,08223328 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03955142 0,08216336 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03955142 0,08209355 ! artery development GO:0060840 25 9 0,000 0,03955142 0,08202386 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03955142 0,08195429 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03955142 0,08188484 ! equilibrioception GO:0050957 20 9 0,000 0,03955142 0,0818155 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03955142 0,08174629 ! chemosensory behavior GO:0007635 21 9 0,000 0,03955142 0,08167718 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03955142 0,0816082 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03955142 0,08153933 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03955142 0,08147058 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03955142 0,08140195 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03955142 0,08133343 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03955142 0,08126502 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03955142 0,08119673 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03955142 0,08112856 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03955142 0,08106049 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03955142 0,08099255 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03955142 0,08092471 ! protein targeting to ER GO:0045047 25 9 0,000 0,03955142 0,080857 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03955142 0,08078939 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03955142 0,0807219 ! T cell selection GO:0045058 27 9 0,000 0,03955142 0,08065452 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03955142 0,08058725 ! glycine catabolic process GO:0006546 15 9 0,000 0,03955142 0,08052009 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03955142 0,08045305 ! endosome organization GO:0007032 20 9 0,000 0,03955142 0,08038611 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03955142 0,08031929 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03955142 0,08025258 ! mannose metabolic process GO:0006013 13 9 0,000 0,03955142 0,08018598 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03955142 0,08011949 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03955142 0,08005311 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03955142 0,07998685 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03955142 0,07992069 ! receptor clustering GO:0043113 20 9 0,000 0,03955142 0,07985464 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03955142 0,07978869 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03955142 0,07972286 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03955142 0,07965714 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03955142 0,07959152 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03955142 0,07952602 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03955142 0,07946062 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03955142 0,07939532 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03955142 0,07933014 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03955142 0,07926506 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03955142 0,07920009 ! response to amine stimulus GO:0014075 13 9 0,000 0,03955142 0,07913522 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03955142 0,07907047 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03955142 0,07900581 ! erythrocyte development GO:0048821 17 9 0,000 0,03955142 0,07894127 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03955142 0,07887682 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03955142 0,07881249 ! renal water homeostasis GO:0003091 15 9 0,000 0,03955142 0,07874826 ! postreplication repair GO:0006301 25 9 0,000 0,03955142 0,07868413 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03955142 0,07862011 ! icosanoid secretion GO:0032309 15 9 0,000 0,03955142 0,07855619 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03955142 0,07849237 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03955142 0,07842866 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03955142 0,07836505 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03955142 0,07830155 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03955142 0,07823815 ! sterol catabolic process GO:0016127 14 9 0,000 0,03955142 0,07817485 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03955142 0,07811165 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03955142 0,07804855 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03955142 0,07798556 ! S phase GO:0051320 10 9 0,000 0,03955142 0,07792267 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03955142 0,07785988 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03955142 0,07779719 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03955142 0,0777346 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03955142 0,07767211 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03955142 0,07760973 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03955142 0,07754744 ! purine base metabolic process GO:0006144 25 9 0,000 0,03955142 0,07748525 ! pigment granule transport GO:0051904 17 9 0,000 0,03955142 0,07742316 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03955142 0,07736118 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03955142 0,07729929 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03955142 0,0772375 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03955142 0,07717581 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03955142 0,07711421 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03955142 0,07705272 ! mitochondrion localization GO:0051646 18 9 0,000 0,03955142 0,07699132 ! appendage morphogenesis GO:0035107 150 72 1,000 0,04145077 0,08062439 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,04145077 0,08056025 ! actin filament organization GO:0007015 167 72 1,000 0,04145077 0,08049621 ! appendage development GO:0048736 151 73 1,000 0,04249602 0,08246051 GO:0060173|limb development, ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,04355111 0,08444076 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04384891 0,08495074 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,04384891 0,08488342 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04384891 0,08481621 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04384891 0,08474911 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04384891 0,08468212 ! associative learning GO:0008306 21 10 0,000 0,04384891 0,08461523 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,04384891 0,08454844 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04384891 0,08448177 ! phosphate transport GO:0006817 24 10 0,000 0,04384891 0,08441519 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04384891 0,08434872 ! CTP metabolic process GO:0046036 11 10 0,000 0,04384891 0,08428236 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04384891 0,0842161 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04384891 0,08414994 ! GTP metabolic process GO:0046039 11 10 0,000 0,04384891 0,08408389 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04384891 0,08401794 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04384891 0,0839521 ! social behavior GO:0035176 29 10 0,000 0,04384891 0,08388636 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04384891 0,08382072 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04384891 0,08375518 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04384891 0,08368975 ! androgen metabolic process GO:0008209 17 10 0,000 0,04384891 0,08362442 ! phospholipid efflux GO:0033700 19 10 0,000 0,04384891 0,08355919 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04384891 0,08349406 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04384891 0,08342903 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04384891 0,08336411 ! lung alveolus development GO:0048286 26 10 0,000 0,04384891 0,08329928 ! pathogenesis GO:0009405 17 10 0,000 0,04384891 0,08323456 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04384891 0,08316994 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04384891 0,08310541 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04384891 0,08304099 ! endoderm development GO:0007492 18 10 0,000 0,04384891 0,08297667 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04384891 0,08291244 ! arginine catabolic process GO:0006527 17 10 0,000 0,04384891 0,08284832 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04384891 0,0827843 ! proline metabolic process GO:0006560 13 10 0,000 0,04384891 0,08272037 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04384891 0,08265654 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04384891 0,08259281 ! V(D)J recombination GO:0033151 34 10 0,000 0,04384891 0,08252918 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04384891 0,08246565 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04384891 0,08240221 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04384891 0,08233888 ! B cell proliferation GO:0042100 19 10 0,000 0,04384891 0,08227564 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04384891 0,08221249 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04384891 0,08214945 ! multicellular organism growth GO:0035264 19 10 0,000 0,04384891 0,0820865 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04384891 0,08202364 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04384891 0,08196089 ! ruffle organization GO:0031529 17 10 0,000 0,04384891 0,08189823 ! epithelial cell development GO:0002064 21 10 0,000 0,04384891 0,08183566 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04384891 0,08177319 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04384891 0,08171082 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04384891 0,08164854 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04384891 0,08158635 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04384891 0,08152426 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04384891 0,08146227 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,04384891 0,08140036 ! motor axon guidance GO:0008045 22 10 0,000 0,04384891 0,08133856 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04384891 0,08127684 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04384891 0,08121522 ! brain morphogenesis GO:0048854 23 10 0,000 0,04384891 0,0811537 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04384891 0,08109226 ! segment specification GO:0007379 15 10 0,000 0,04384891 0,08103092 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04384891 0,08096967 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04384891 0,08090852 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04384891 0,08084746 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04384891 0,08078648 ! DNA ligation GO:0006266 18 10 0,000 0,04384891 0,08072561 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04384891 0,08066482 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04384891 0,08060412 ! melanosome localization GO:0032400 16 10 0,000 0,04384891 0,08054352 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04384891 0,080483 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04384891 0,08042258 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04384891 0,08036225 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04384891 0,08030201 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04384891 0,08024186 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04384891 0,0801818 ! protein sumoylation GO:0016925 17 10 0,000 0,04384891 0,08012182 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04384891 0,08006194 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04384891 0,08000215 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04384891 0,07994245 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04384891 0,07988283 ! salivary gland development GO:0007431 28 10 0,000 0,04384891 0,07982331 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04384891 0,07976387 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04384891 0,07970452 ! midbrain development GO:0030901 14 10 0,000 0,04384891 0,07964526 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04384891 0,07958609 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04384891 0,07952701 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04384891 0,07946801 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04384891 0,0794091 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04384891 0,07935028 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04384891 0,07929155 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04384891 0,0792329 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04384891 0,07917434 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04384891 0,07911586 ! detection of calcium ion GO:0005513 24 10 0,000 0,04384891 0,07905748 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04384891 0,07899917 ! blastocyst formation GO:0001825 18 10 0,000 0,04384891 0,07894096 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04384891 0,07888283 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04384891 0,07882478 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04384891 0,07876682 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04384891 0,07870895 ! response to nicotine GO:0035094 20 10 0,000 0,04384891 0,07865116 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04384891 0,07859345 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,04569032 0,08183391 ! learning or memory GO:0007611 161 76 1,000 0,04569032 0,08177396 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,04569032 0,0817141 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,04677424 0,08359142 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,04677424 0,08353031 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04812729 0,08588383 ! respiratory burst GO:0045730 17 11 0,000 0,04812729 0,08582114 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04812729 0,08575855 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04812729 0,08569604 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04812729 0,08563362 ! thyroid gland development GO:0030878 26 11 0,000 0,04812729 0,0855713 ! synapsis GO:0007129 14 11 0,000 0,04812729 0,08550907 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04812729 0,08544692 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04812729 0,08538487 ! response to pain GO:0048265 27 11 0,000 0,04812729 0,08532291 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04812729 0,08526103 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04812729 0,08519925 ! blood vessel remodeling GO:0001974 30 11 0,000 0,04812729 0,08513756 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,04812729 0,08507595 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,04812729 0,08501444 ! bone resorption GO:0045453 16 11 0,000 0,04812729 0,08495301 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04812729 0,08489167 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04812729 0,08483042 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04812729 0,08476926 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04812729 0,08470819 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04812729 0,0846472 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04812729 0,08458631 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04812729 0,0845255 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,04812729 0,08446477 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04812729 0,08440414 ! UV protection GO:0009650 20 11 0,000 0,04812729 0,08434359 ! adult heart development GO:0007512 16 11 0,000 0,04812729 0,08428313 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04812729 0,08422275 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04812729 0,08416247 ! macroautophagy GO:0016236 19 11 0,000 0,04812729 0,08410226 ! temperature homeostasis GO:0001659 18 11 0,000 0,04812729 0,08404215 ! behavioral fear response GO:0001662 27 11 0,000 0,04812729 0,08398212 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04812729 0,08392217 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04812729 0,08386232 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04812729 0,08380254 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04812729 0,08374285 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04812729 0,08368325 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04812729 0,08362373 ! regulation of organ growth GO:0046620 14 11 0,000 0,04812729 0,0835643 ! pigment granule localization GO:0051875 20 11 0,000 0,04812729 0,08350495 ! vasoconstriction GO:0042310 20 11 0,000 0,04812729 0,08344568 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04812729 0,0833865 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04812729 0,0833274 ! embryonic axis specification GO:0000578 19 11 0,000 0,04812729 0,08326839 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04812729 0,08320946 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04812729 0,08315061 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04812729 0,08309185 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04812729 0,08303317 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04812729 0,08297457 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04812729 0,08291605 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04812729 0,08285762 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04812729 0,08279927 ! prophase GO:0051324 17 11 0,000 0,04812729 0,082741 ! nucleosome positioning GO:0016584 15 11 0,000 0,04812729 0,08268282 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04812729 0,08262471 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04812729 0,08256669 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04812729 0,08250875 ! apical protein localization GO:0045176 18 11 0,000 0,04812729 0,08245089 ! acid secretion GO:0046717 20 11 0,000 0,04812729 0,08239311 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04812729 0,08233541 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,04812729 0,08227779 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04812729 0,08222026 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04812729 0,0821628 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04812729 0,08210542 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04812729 0,08204813 ! cholesterol efflux GO:0033344 21 11 0,000 0,04812729 0,08199091 ! oocyte development GO:0048599 20 11 0,000 0,04812729 0,08193377 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04812729 0,08187672 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04812729 0,08181974 ! embryonic gut development GO:0048566 19 11 0,000 0,04812729 0,08176284 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04812729 0,08170602 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04812729 0,08164928 ! activation of innate immune response GO:0002218 16 11 0,000 0,04812729 0,08159262 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04812729 0,08153604 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04812729 0,08147953 ! lysogeny GO:0030069 22 11 0,000 0,04812729 0,08142311 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04812729 0,08136676 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04812729 0,08131049 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04812729 0,0812543 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,04897018 0,08262027 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,05008199 0,08443775 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,05233277 0,08817169 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05238665 0,08820164 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05238665 0,08814089 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05238665 0,08808023 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,05238665 0,08801965 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,05238665 0,08795916 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05238665 0,08789875 ! protein complex disassembly GO:0043241 28 12 0,000 0,05238665 0,08783842 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05238665 0,08777817 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05238665 0,08771801 ! T cell proliferation GO:0042098 32 12 0,000 0,05238665 0,08765793 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05238665 0,08759793 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05238665 0,08753801 ! drug transport GO:0015893 16 12 0,000 0,05238665 0,08747818 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05238665 0,08741843 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05238665 0,08735876 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05238665 0,08729917 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05238665 0,08723966 ! focal adhesion formation GO:0048041 37 12 0,000 0,05238665 0,08718023 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05238665 0,08712088 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05238665 0,08706162 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05238665 0,08700243 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05238665 0,08694333 ! lipid digestion GO:0044241 21 12 0,000 0,05238665 0,0868843 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05238665 0,08682536 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05238665 0,08676649 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05238665 0,08670771 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05238665 0,086649 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05238665 0,08659038 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05238665 0,08653183 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05238665 0,08647336 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05238665 0,08641497 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05238665 0,08635666 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05238665 0,08629843 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05238665 0,08624028 ! cranial nerve development GO:0021545 23 12 0,000 0,05238665 0,08618221 ! fucose catabolic process GO:0019317 25 12 0,000 0,05238665 0,08612421 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05238665 0,08606629 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05238665 0,08600845 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05238665 0,08595069 ! zymogen activation GO:0031638 18 12 0,000 0,05238665 0,085893 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05238665 0,0858354 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05238665 0,08577787 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,05238665 0,08572041 ! oocyte differentiation GO:0009994 21 12 0,000 0,05238665 0,08566304 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05238665 0,08560574 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05238665 0,08554851 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,05238665 0,08549137 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,05238665 0,0854343 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05238665 0,0853773 ! defense response to fungus GO:0050832 15 12 0,000 0,05238665 0,08532038 ! embryonic placenta development GO:0001892 21 12 0,000 0,05238665 0,08526354 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05238665 0,08520678 ! response to cold GO:0009409 17 12 0,000 0,05238665 0,08515008 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05238665 0,08509347 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05238665 0,08503693 ! inorganic anion transport GO:0015698 156 83 1,000 0,05347154 0,08674035 ! cholesterol metabolic process GO:0008203 148 85 1,000 0,05577533 0,09041748 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,05577533 0,09035752 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05662706 0,09167655 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05662706 0,09161584 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05662706 0,09155521 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05662706 0,09149465 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05662706 0,09143418 ! peroxisomal transport GO:0043574 28 13 0,000 0,05662706 0,09137379 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05662706 0,09131348 ! cartilage condensation GO:0001502 22 13 0,000 0,05662706 0,09125324 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05662706 0,09119309 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05662706 0,09113302 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05662706 0,09107302 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05662706 0,0910131 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05662706 0,09095327 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05662706 0,09089351 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05662706 0,09083383 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05662706 0,09077422 ! methionine metabolic process GO:0006555 31 13 0,000 0,05662706 0,0907147 ! plasma membrane organization GO:0007009 27 13 0,000 0,05662706 0,09065525 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05662706 0,09059589 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05662706 0,0905366 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05662706 0,09047738 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05662706 0,09041825 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,05662706 0,09035919 ! cytokine metabolic process GO:0042107 24 13 0,000 0,05662706 0,09030021 ! exocrine system development GO:0035272 34 13 0,000 0,05662706 0,0902413 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05662706 0,09018248 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05662706 0,09012372 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05662706 0,09006505 ! L-glutamate transport GO:0015813 30 13 0,000 0,05662706 0,09000645 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05662706 0,08994793 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05662706 0,08988949 ! protein homotetramerization GO:0051289 24 13 0,000 0,05662706 0,08983112 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05662706 0,08977282 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05662706 0,0897146 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05662706 0,08965646 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05662706 0,08959839 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05662706 0,0895404 ! histone methylation GO:0016571 29 13 0,000 0,05662706 0,08948248 ! chromatin silencing GO:0006342 29 13 0,000 0,05662706 0,08942464 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05662706 0,08936687 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05662706 0,08930918 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05662706 0,08925156 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05662706 0,08919402 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05662706 0,08913654 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05662706 0,08907915 ! spleen development GO:0048536 24 13 0,000 0,05662706 0,08902183 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05662706 0,08896458 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05662706 0,0889074 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05662706 0,0888503 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05662706 0,08879327 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05662706 0,08873632 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05662706 0,08867943 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05662706 0,08862262 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05662706 0,08856589 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05662706 0,08850922 ! insulin secretion GO:0030073 24 13 0,000 0,05662706 0,08845263 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05662706 0,08839611 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05662706 0,08833967 ! acrosome reaction GO:0007340 19 13 0,000 0,05662706 0,08828329 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05662706 0,08822699 ! mitochondrion organization GO:0007005 159 87 1,000 0,05811346 0,09048514 ! regulation of protein transport GO:0051223 165 87 1,000 0,05811346 0,09042751 GO:0070201|regulation of establishment of protein localization, ! regulation of neurological system process GO:0031644 175 89 1,000 0,06048515 0,09405806 ! rRNA transcription GO:0009303 28 14 0,000 0,06084863 0,0945631 ! regulation of S phase GO:0033261 26 14 0,000 0,06084863 0,09450298 ! water transport GO:0006833 21 14 0,000 0,06084863 0,09444294 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06084863 0,09438298 ! non-recombinational repair GO:0000726 29 14 0,000 0,06084863 0,09432309 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06084863 0,09426328 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06084863 0,09420354 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06084863 0,09414388 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06084863 0,0940843 ! palate development GO:0060021 32 14 0,000 0,06084863 0,09402479 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,06084863 0,09396536 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06084863 0,093906 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06084863 0,09384671 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06084863 0,0937875 ! arginine metabolic process GO:0006525 21 14 0,000 0,06084863 0,09372837 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06084863 0,09366931 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06084863 0,09361032 ! regulation of heart rate GO:0002027 25 14 0,000 0,06084863 0,09355141 ! fear response GO:0042596 34 14 0,000 0,06084863 0,09349257 ! organic alcohol transport GO:0015850 29 14 0,000 0,06084863 0,09343381 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06084863 0,09337512 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06084863 0,0933165 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06084863 0,09325796 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06084863 0,09319949 ! bone mineralization GO:0030282 18 14 0,000 0,06084863 0,0931411 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06084863 0,09308278 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06084863 0,09302453 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06084863 0,09296635 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06084863 0,09290824 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06084863 0,09285021 ! regulation of cellular pH GO:0030641 27 14 0,000 0,06084863 0,09279225 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06084863 0,09273437 ! ribosome assembly GO:0042255 18 14 0,000 0,06084863 0,09267655 ! cerebellum development GO:0021549 23 14 0,000 0,06084863 0,09261881 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06084863 0,09256114 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06084863 0,09250354 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06084863 0,09244601 ! response to gamma radiation GO:0010332 30 14 0,000 0,06084863 0,09238856 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06084863 0,09233118 ! NADP metabolic process GO:0006739 24 14 0,000 0,06084863 0,09227386 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06084863 0,09221662 ! oxygen transport GO:0015671 22 14 0,000 0,06084863 0,09215945 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06084863 0,09210235 ! male genitalia development GO:0030539 26 14 0,000 0,06084863 0,09204532 ! regulation of RNA stability GO:0043487 33 14 0,000 0,06084863 0,09198836 ! regulation of axon extension GO:0030516 43 14 0,000 0,06084863 0,09193147 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,06084863 0,09187466 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06084863 0,09181791 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,06168332 0,09301998 ! ossification GO:0001503 205 91 1,000 0,0628896 0,09478056 ! defense response to bacterium GO:0042742 112 91 1,000 0,0628896 0,09472213 ! bone development GO:0060348 206 92 1,000 0,06410388 0,09649154 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06505141 0,09785751 ! lactation GO:0007595 30 15 0,000 0,06505141 0,09779729 ! reproductive cellular process GO:0048610 22 15 0,000 0,06505141 0,09773715 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06505141 0,09767708 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06505141 0,09761708 ! superoxide anion generation GO:0042554 22 15 0,000 0,06505141 0,09755715 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06505141 0,0974973 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,06505141 0,09743753 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06505141 0,09737782 ! copper ion transport GO:0006825 22 15 0,000 0,06505141 0,09731819 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06505141 0,09725863 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06505141 0,09719915 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06505141 0,09713973 ! response to cAMP GO:0051591 25 15 0,000 0,06505141 0,09708039 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06505141 0,09702113 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06505141 0,09696193 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,06505141 0,09690281 ! response to hexose stimulus GO:0009746 25 15 0,000 0,06505141 0,09684376 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06505141 0,09678478 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,06505141 0,09672587 ! vesicle coating GO:0006901 38 15 0,000 0,06505141 0,09666703 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,06505141 0,09660827 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,06505141 0,09654958 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,06505141 0,09649096 ! regulation of exocytosis GO:0017157 26 15 0,000 0,06505141 0,09643241 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06505141 0,09637393 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,06505141 0,09631552 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06505141 0,09625718 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06505141 0,09619891 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06505141 0,09614072 ! histone deacetylation GO:0016575 24 15 0,000 0,06505141 0,09608259 ! water homeostasis GO:0030104 28 15 0,000 0,06505141 0,09602453 ! cofactor transport GO:0051181 30 15 0,000 0,06505141 0,09596655 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06505141 0,09590863 ! muscle maintenance GO:0046716 26 15 0,000 0,06505141 0,09585079 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06505141 0,09579301 ! intestinal absorption GO:0050892 31 15 0,000 0,06505141 0,0957353 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06505141 0,09567767 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06505141 0,0956201 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06505141 0,0955626 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,06505141 0,09550517 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06505141 0,09544781 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06505141 0,09539052 ! actin filament polymerization GO:0030041 27 15 0,000 0,06505141 0,0953333 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06505141 0,09527614 ! sterol metabolic process GO:0016125 166 94 1,000 0,06655606 0,09742148 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,06655606 0,09736315 ! regulation of membrane potential GO:0042391 179 94 1,000 0,06655606 0,09730488 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06923551 0,1011617 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06923551 0,10110123 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06923551 0,10104083 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06923551 0,10098051 ! bone remodeling GO:0046849 28 16 0,000 0,06923551 0,10092026 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06923551 0,10086008 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06923551 0,10079997 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06923551 0,10073994 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06923551 0,10067997 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06923551 0,10062008 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06923551 0,10056026 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06923551 0,10050051 ! startle response GO:0001964 28 16 0,000 0,06923551 0,10044083 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06923551 0,10038122 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06923551 0,10032168 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06923551 0,10026221 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06923551 0,10020282 ! lysosomal transport GO:0007041 31 16 0,000 0,06923551 0,10014349 ! fructose metabolic process GO:0006000 25 16 0,000 0,06923551 0,10008423 ! L-amino acid transport GO:0015807 33 16 0,000 0,06923551 0,10002505 ! stem cell development GO:0048864 46 16 0,000 0,06923551 0,09996593 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06923551 0,09990688 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06923551 0,09984791 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06923551 0,099789 ! axon cargo transport GO:0008088 46 16 0,000 0,06923551 0,09973016 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06923551 0,09967139 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06923551 0,09961269 ! DNA replication initiation GO:0006270 28 16 0,000 0,06923551 0,09955406 ! neuron recognition GO:0008038 40 16 0,000 0,06923551 0,0994955 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06923551 0,09943701 ! tissue regeneration GO:0042246 27 16 0,000 0,06923551 0,09937859 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06923551 0,09932023 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06923551 0,09926195 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,06923551 0,09920373 ! biomineral formation GO:0031214 22 16 0,000 0,06923551 0,09914558 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06923551 0,0990875 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06923551 0,09902948 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06923551 0,09897154 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06923551 0,09891366 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06923551 0,09885585 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06923551 0,0987981 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,06923551 0,09874043 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06923551 0,09868282 ! peptide hormone processing GO:0016486 27 16 0,000 0,06923551 0,09862528 ! regulation of protein localization GO:0032880 188 97 1,000 0,070292 0,10007189 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,073401 0,10443719 ! metencephalon development GO:0022037 32 17 0,000 0,073401 0,1043764 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,073401 0,10431568 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,073401 0,10425503 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,073401 0,10419445 ! signal complex assembly GO:0007172 47 17 0,000 0,073401 0,10413394 ! endothelial cell migration GO:0043542 31 17 0,000 0,073401 0,10407351 ! gene silencing by RNA GO:0031047 38 17 0,000 0,073401 0,10401314 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,073401 0,10395284 ! glial cell development GO:0021782 28 17 0,000 0,073401 0,10389261 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,073401 0,10383245 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,073401 0,10377237 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,073401 0,10371235 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,073401 0,1036524 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,073401 0,10359252 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,073401 0,10353271 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,073401 0,10347297 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,073401 0,10341329 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,073401 0,10335369 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,073401 0,10329415 ! membrane budding GO:0006900 42 17 0,000 0,073401 0,10323469 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,073401 0,10317529 ! regulation of protein binding GO:0043393 33 17 0,000 0,073401 0,10311596 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,073401 0,1030567 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,073401 0,1029975 ! genitalia development GO:0048806 32 17 0,000 0,073401 0,10293838 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,073401 0,10287932 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,073401 0,10282033 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,073401 0,1027614 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,073401 0,10270255 ! steroid catabolic process GO:0006706 34 17 0,000 0,073401 0,10264376 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,073401 0,10258504 ! gas transport GO:0015669 26 17 0,000 0,073401 0,10252639 ! organic cation transport GO:0015695 32 17 0,000 0,073401 0,1024678 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,073401 0,10240928 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,073401 0,10235083 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,073401 0,10229244 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07754797 0,10801008 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07754797 0,10794854 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07754797 0,10788706 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07754797 0,10782566 ! adult walking behavior GO:0007628 36 18 0,000 0,07754797 0,10776433 ! patterning of blood vessels GO:0001569 43 18 0,000 0,07754797 0,10770306 ! heart looping GO:0001947 34 18 0,000 0,07754797 0,10764187 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07754797 0,10758074 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,07754797 0,10751969 ! centrosome cycle GO:0007098 26 18 0,000 0,07754797 0,1074587 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07754797 0,10739778 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,07754797 0,10733693 ! glycine metabolic process GO:0006544 30 18 0,000 0,07754797 0,10727615 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07754797 0,10721544 ! response to retinoic acid GO:0032526 31 18 0,000 0,07754797 0,1071548 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,07754797 0,10709423 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07754797 0,10703372 ! DNA integration GO:0015074 32 18 0,000 0,07754797 0,10697328 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07754797 0,10691292 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07754797 0,10685261 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07754797 0,10679238 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07754797 0,10673222 ! neural crest cell migration GO:0001755 41 18 0,000 0,07754797 0,10667212 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,07754797 0,10661209 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07754797 0,10655213 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,07754797 0,10649223 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07754797 0,10643241 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,07754797 0,10637265 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,07754797 0,10631296 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07754797 0,10625333 ! detection of bacterium GO:0016045 22 18 0,000 0,07754797 0,10619377 ! nerve development GO:0021675 34 18 0,000 0,07754797 0,10613428 ! defense response to virus GO:0051607 43 18 0,000 0,07754797 0,10607485 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07754797 0,10601549 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,07754797 0,1059562 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,08167649 0,11153475 ! positive regulation of translation GO:0045727 31 19 0,000 0,08167649 0,11147244 ! negative regulation of defense response GO:0031348 27 19 0,000 0,08167649 0,1114102 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,08167649 0,11134803 ! neuron maturation GO:0042551 46 19 0,000 0,08167649 0,11128593 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,08167649 0,11122389 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,08167649 0,11116193 ! inositol metabolic process GO:0006020 33 19 0,000 0,08167649 0,11110004 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08167649 0,11103821 ! memory GO:0007613 34 19 0,000 0,08167649 0,11097645 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,08167649 0,11091477 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,08167649 0,11085315 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,08167649 0,1107916 ! cerebral cortex development GO:0021987 40 19 0,000 0,08167649 0,11073011 ! pigmentation during development GO:0048066 42 19 0,000 0,08167649 0,1106687 ! response to vitamin A GO:0033189 32 19 0,000 0,08167649 0,11060735 ! heme metabolic process GO:0042168 40 19 0,000 0,08167649 0,11054607 ! neuromuscular junction development GO:0007528 43 19 0,000 0,08167649 0,11048486 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,08167649 0,11042372 ! response to fungus GO:0009620 26 19 0,000 0,08167649 0,11036265 ! protein export from nucleus GO:0006611 40 19 0,000 0,08167649 0,11030164 ! heart process GO:0003015 32 19 0,000 0,08167649 0,1102407 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,08167649 0,11017983 ! cellular pigmentation GO:0033059 37 19 0,000 0,08167649 0,11011902 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,08167649 0,11005828 ! vitamin transport GO:0051180 31 19 0,000 0,08167649 0,10999761 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,08167649 0,10993701 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,08167649 0,10987647 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,08167649 0,109816 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,08167649 0,10975559 ! cilium assembly GO:0042384 38 19 0,000 0,08167649 0,10969525 ! peptide hormone secretion GO:0030072 32 19 0,000 0,08167649 0,10963498 ! protein secretion GO:0009306 45 20 0,000 0,08578665 0,11508884 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08578665 0,11502568 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,08578665 0,11496258 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08578665 0,11489955 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,08578665 0,1148366 ! skin development GO:0043588 42 20 0,000 0,08578665 0,11477371 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08578665 0,11471088 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08578665 0,11464813 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08578665 0,11458545 ! response to vitamin GO:0033273 36 20 0,000 0,08578665 0,11452283 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08578665 0,11446029 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,08578665 0,11439781 ! response to alkaloid GO:0043279 38 20 0,000 0,08578665 0,1143354 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08578665 0,11427306 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08578665 0,11421078 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,08578665 0,11414858 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,08578665 0,11408644 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08578665 0,11402437 ! peptide secretion GO:0002790 38 20 0,000 0,08578665 0,11396236 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08578665 0,11390043 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08578665 0,11383856 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08578665 0,11377676 ! cell-cell junction organization GO:0045216 43 20 0,000 0,08578665 0,11371502 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08578665 0,11365335 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08578665 0,11359175 ! regulation of glucose import GO:0046324 30 20 0,000 0,08578665 0,11353022 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,08578665 0,11346875 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,08578665 0,11340735 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08578665 0,11334602 ! negative regulation of translation GO:0017148 32 20 0,000 0,08578665 0,11328475 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08987853 0,11862412 ! hormone secretion GO:0046879 39 21 0,000 0,08987853 0,11856007 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08987853 0,11849609 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08987853 0,11843217 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08987853 0,11836833 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08987853 0,11830455 ! ovarian follicle development GO:0001541 39 21 0,000 0,08987853 0,11824084 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08987853 0,11817721 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08987853 0,11811364 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,08987853 0,11805013 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08987853 0,1179867 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08987853 0,11792333 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08987853 0,11786004 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08987853 0,11779681 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,08987853 0,11773364 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08987853 0,11767055 ! collagen fibril organization GO:0030199 62 21 0,000 0,08987853 0,11760752 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,08987853 0,11754457 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08987853 0,11748167 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08987853 0,11741885 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08987853 0,11735609 ! collagen catabolic process GO:0030574 29 21 0,000 0,08987853 0,1172934 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08987853 0,11723078 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08987853 0,11716822 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08987853 0,11710573 ! actin filament-based movement GO:0030048 47 21 0,000 0,08987853 0,11704331 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,08987853 0,11698095 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,09395221 0,12221792 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,09395221 0,12215287 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,09395221 0,1220879 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,09395221 0,12202299 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,09395221 0,12195815 ! microtubule-based transport GO:0010970 59 22 0,000 0,09395221 0,12189339 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,09395221 0,12182869 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,09395221 0,12176406 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,09395221 0,12169949 ! vacuolar transport GO:0007034 41 22 0,000 0,09395221 0,121635 ! fucose metabolic process GO:0006004 44 22 0,000 0,09395221 0,12157058 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09395221 0,12150622 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09395221 0,12144193 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,09395221 0,12137771 ! ureteric bud development GO:0001657 50 22 0,000 0,09395221 0,12131356 ! stem cell differentiation GO:0048863 57 22 0,000 0,09395221 0,12124947 ! renal system process GO:0003014 42 22 0,000 0,09395221 0,12118545 ! vasodilation GO:0042311 40 22 0,000 0,09395221 0,1211215 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09395221 0,12105762 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,09395221 0,1209938 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,09395221 0,12093006 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,09395221 0,12086638 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,09395221 0,12080276 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09395221 0,12073921 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09395221 0,12067573 ! sarcomere organization GO:0045214 32 22 0,000 0,09395221 0,12061232 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,09395221 0,12054897 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09395221 0,12048569 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,09395221 0,12042248 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,09395221 0,12035933 ! gut development GO:0048565 44 22 0,000 0,09395221 0,12029625 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09395221 0,12023324 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,09395221 0,12017029 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,09800777 0,12529198 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,09800777 0,12522645 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,09800777 0,12516099 ! gluconeogenesis GO:0006094 38 23 0,000 0,09800777 0,1250956 ! glycerol metabolic process GO:0006071 40 23 0,000 0,09800777 0,12503028 ! viral genome replication GO:0019079 44 23 0,000 0,09800777 0,12496502 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,09800777 0,12489983 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,09800777 0,12483471 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,09800777 0,12476966 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,09800777 0,12470468 ! regeneration GO:0031099 42 23 0,000 0,09800777 0,12463976 ! axis specification GO:0009798 43 23 0,000 0,09800777 0,12457491 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,09800777 0,12451013 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,09800777 0,12444542 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,09800777 0,12438077 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,09800777 0,12431619 ! peroxisome organization GO:0007031 43 23 0,000 0,09800777 0,12425168 ! lysosome organization GO:0007040 47 23 0,000 0,09800777 0,12418723 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,09800777 0,12412285 ! vesicle targeting GO:0006903 49 23 0,000 0,09800777 0,12405854 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,09800777 0,12399429 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,09800777 0,12393011 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,09800777 0,123866 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,09800777 0,12380195 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,09800777 0,12373797 ! DNA modification GO:0006304 36 23 0,000 0,09800777 0,12367406 ! fatty acid transport GO:0015908 47 23 0,000 0,09800777 0,12361021 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,09800777 0,12354643 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,09800777 0,12348271 ! hormone transport GO:0009914 41 23 0,000 0,09800777 0,12341906 ! cell-cell recognition GO:0009988 28 23 0,000 0,09800777 0,12335548 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,09800777 0,12329196 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,09800777 0,1232285 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,10204529 0,12823901 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,10204529 0,12817308 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,10204529 0,12810722 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,10204529 0,12804142 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,10204529 0,12797569 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,10204529 0,12791003 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,10204529 0,12784443 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,10204529 0,1277789 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,10204529 0,12771344 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,10204529 0,12764805 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,10204529 0,12758272 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,10204529 0,12751746 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,10204529 0,12745227 ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,10204529 0,12738714 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,10204529 0,12732208 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,10204529 0,12725709 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,10204529 0,12719216 ! oogenesis GO:0048477 44 24 0,000 0,10204529 0,1271273 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,10204529 0,12706251 ! platelet activation GO:0030168 41 24 0,000 0,10204529 0,12699778 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,10204529 0,12693312 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,10204529 0,12686852 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,10204529 0,12680399 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,10204529 0,12673952 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,10204529 0,12667512 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,10204529 0,12661079 ! regulation of amine transport GO:0051952 41 24 0,000 0,10204529 0,12654652 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,10606485 0,13146445 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,10606485 0,13139778 ! leukocyte adhesion GO:0007159 55 25 0,000 0,10606485 0,13133119 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,10606485 0,13126465 ! phototransduction GO:0007602 37 25 0,000 0,10606485 0,13119819 ! keratinization GO:0031424 37 25 0,000 0,10606485 0,1311318 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,10606485 0,13106547 ! vacuole organization GO:0007033 49 25 0,000 0,10606485 0,13099921 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,10606485 0,13093301 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,10606485 0,13086688 ! receptor metabolic process GO:0043112 53 25 0,000 0,10606485 0,13080082 ! chromosome condensation GO:0030261 48 25 0,000 0,10606485 0,13073483 ! regulation of behavior GO:0050795 48 25 0,000 0,10606485 0,1306689 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,10606485 0,13060304 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,10606485 0,13053724 ! immunoglobulin production GO:0002377 62 25 0,000 0,10606485 0,13047152 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,10606485 0,13040585 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,10606485 0,13034026 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,11006653 0,13518981 ! myelination GO:0042552 50 26 0,000 0,11006653 0,13512188 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,11006653 0,13505401 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,11006653 0,13498621 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,11006653 0,13491848 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,11006653 0,13485082 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,11006653 0,13478323 GO:0051297|centrosome organization, ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,11006653 0,1347157 ! digestive system process GO:0022600 49 26 0,000 0,11006653 0,13464824 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,11006653 0,13458085 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,11006653 0,13451352 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 0,000 0,11006653 0,13444627 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,11006653 0,13437908 ! neural crest cell development GO:0014032 59 26 0,000 0,11006653 0,13431196 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,11006653 0,1342449 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,11006653 0,13417791 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,11006653 0,13411099 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,11006653 0,13404413 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,11006653 0,13397735 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,11006653 0,13391062 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,11006653 0,13384397 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,11006653 0,13377738 ! blastocyst development GO:0001824 50 26 0,000 0,11006653 0,13371086 ! telomere organization GO:0032200 46 26 0,000 0,11006653 0,1336444 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,11006653 0,13357801 ! neural tube closure GO:0001843 58 26 0,000 0,11006653 0,13351169 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,11006653 0,13344543 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,11006653 0,13337923 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,11006653 0,13331311 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,11405041 0,13806995 ! embryonic pattern specification GO:0009880 49 27 0,000 0,11405041 0,13800156 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,11405041 0,13793324 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,11405041 0,13786499 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,11405041 0,13779681 ! iron ion transport GO:0006826 65 27 0,000 0,11405041 0,1377287 ! superoxide metabolic process GO:0006801 41 27 0,000 0,11405041 0,13766065 ! tube lumen formation GO:0035148 59 27 0,000 0,11405041 0,13759267 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,11405041 0,13752475 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,11405041 0,13745691 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,11405041 0,13738913 ! response to toxin GO:0009636 49 27 0,000 0,11405041 0,13732142 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,11405041 0,13725377 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,11405041 0,13718619 ! leukocyte proliferation GO:0070661 59 27 0,000 0,11405041 0,13711868 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,11405041 0,13705123 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,11801657 0,14174753 ! circadian rhythm GO:0007623 56 28 0,000 0,11801657 0,14167787 ! dendrite development GO:0016358 67 28 0,000 0,11801657 0,14160829 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,11801657 0,14153877 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,11801657 0,14146932 ! sperm motility GO:0030317 37 28 0,000 0,11801657 0,14139994 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,11801657 0,14133062 ! base-excision repair GO:0006284 41 28 0,000 0,11801657 0,14126138 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,11801657 0,1411922 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,11801657 0,14112309 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,11801657 0,14105405 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,11801657 0,14098507 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,11801657 0,14091616 ! glutathione metabolic process GO:0006749 42 28 0,000 0,11801657 0,14084732 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,11801657 0,14077855 ! lipid oxidation GO:0034440 48 28 0,000 0,11801657 0,14070984 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,11801657 0,14064121 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,11801657 0,14057263 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,12196508 0,14520501 ! translational initiation GO:0006413 66 29 0,000 0,12196508 0,14513429 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,12196508 0,14506363 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,12196508 0,14499304 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,12196508 0,14492251 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,12196508 0,14485206 ! autophagy GO:0006914 47 29 0,000 0,12196508 0,14478168 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,12196508 0,14471136 ! primary neural tube formation GO:0014020 61 29 0,000 0,12196508 0,14464111 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,12196508 0,14457093 ! synaptogenesis GO:0007416 46 29 0,000 0,12196508 0,14450082 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,12196508 0,14443077 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,12196508 0,1443608 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,12589602 0,1489414 ! phenol metabolic process GO:0018958 56 30 0,000 0,12589602 0,14886931 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,12589602 0,14879729 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,12589602 0,14872533 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,12589602 0,14865345 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,12589602 0,14858164 ! acute-phase response GO:0006953 50 30 0,000 0,12589602 0,14850989 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,12589602 0,14843822 ! myofibril assembly GO:0030239 50 30 0,000 0,12589602 0,14836661 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,12589602 0,14829508 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,12589602 0,14822361 ! phospholipid transport GO:0015914 65 30 0,000 0,12589602 0,14815221 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,12589602 0,14808088 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,12589602 0,14800962 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,12589602 0,14793843 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,12589602 0,1478673 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,12589602 0,14779625 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,12589602 0,14772526 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,12980948 0,15224415 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,12980948 0,1521711 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,12980948 0,15209811 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,12980948 0,1520252 ! cell junction assembly GO:0034329 85 31 0,000 0,12980948 0,15195236 ! regulation of innate immune response GO:0045088 57 31 0,000 0,12980948 0,15187958 ! ovulation cycle process GO:0022602 55 31 0,000 0,12980948 0,15180688 ! peptide transport GO:0015833 60 31 0,000 0,12980948 0,15173424 ! male gonad development GO:0008584 56 31 0,000 0,12980948 0,15166168 ! iron ion homeostasis GO:0055072 60 31 0,000 0,12980948 0,15158918 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,12980948 0,15151675 ! detection of light stimulus GO:0009583 44 31 0,000 0,12980948 0,1514444 ! natural killer cell activation GO:0030101 50 31 0,000 0,12980948 0,15137211 ! ensheathment of neurons GO:0007272 64 31 0,000 0,12980948 0,15129989 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,12980948 0,15122774 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,12980948 0,15115566 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,12980948 0,15108364 ! eye morphogenesis GO:0048592 65 31 0,000 0,12980948 0,1510117 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,13370553 0,15547007 ! collagen metabolic process GO:0032963 49 32 0,000 0,13370553 0,1553961 ! spindle organization GO:0007051 50 32 0,000 0,13370553 0,15532221 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,13370553 0,15524839 ! metanephros development GO:0001656 81 32 0,000 0,13370553 0,15517464 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,13370553 0,15510095 ! muscle cell development GO:0055001 52 32 0,000 0,13370553 0,15502734 ! mesoderm formation GO:0001707 73 32 0,000 0,13370553 0,1549538 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,13370553 0,15488033 ! ovulation cycle GO:0042698 57 32 0,000 0,13370553 0,15480692 ! peripheral nervous system development GO:0007422 68 32 0,000 0,13370553 0,15473359 ! BMP signaling pathway GO:0030509 71 32 0,000 0,13370553 0,15466033 ! hindbrain development GO:0030902 65 32 0,000 0,13370553 0,15458713 ! gene silencing GO:0016458 71 32 0,000 0,13370553 0,15451401 ! regulation of pH GO:0006885 56 33 0,000 0,13758424 0,15892118 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,13758424 0,15884608 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,13758424 0,15877104 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,13758424 0,15869608 ! response to ionizing radiation GO:0010212 74 33 0,000 0,13758424 0,15862119 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,13758424 0,15854637 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,13758424 0,15847162 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,13758424 0,15839694 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,13758424 0,15832233 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,13758424 0,15824779 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,13758424 0,15817332 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,13758424 0,15809892 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,1414457 0,16245972 ! glial cell differentiation GO:0010001 67 34 0,000 0,1414457 0,16238338 ! post-embryonic development GO:0009791 76 34 0,000 0,1414457 0,16230711 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,1414457 0,16223091 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,1414457 0,16215478 ! spliceosome assembly GO:0000245 75 34 0,000 0,1414457 0,16207872 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,1414457 0,16200273 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,1414457 0,16192682 ! formation of primary germ layer GO:0001704 76 34 0,000 0,1414457 0,16185098 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,1414457 0,1617752 ! adult locomotory behavior GO:0008344 62 34 0,000 0,1414457 0,1616995 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,14528997 0,16601655 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,14528997 0,16593894 ! negative regulation of secretion GO:0051048 68 35 0,000 0,14528997 0,1658614 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,14528997 0,16578393 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,14528997 0,16570653 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,14528997 0,16562921 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,14528997 0,16555196 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,14528997 0,16547478 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,14528997 0,16539767 ! ceramide metabolic process GO:0006672 72 35 0,000 0,14528997 0,16532063 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,14528997 0,16524366 ! vesicle localization GO:0051648 70 35 0,000 0,14528997 0,16516677 ! regulation of muscle development GO:0048634 82 36 0,000 0,14911714 0,16943868 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,14911714 0,16935991 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,14911714 0,16928121 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,14911714 0,16920258 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,14911714 0,16912403 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,14911714 0,16904555 ! positive regulation of cell development GO:0010720 85 36 0,000 0,14911714 0,16896714 ! protein targeting to membrane GO:0006612 75 36 0,000 0,14911714 0,16888881 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,14911714 0,16881055 ! aerobic respiration GO:0009060 56 36 0,000 0,14911714 0,16873236 ! embryonic organ development GO:0048568 67 36 0,000 0,14911714 0,16865424 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,14911714 0,1685762 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,14911714 0,16849823 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,15292727 0,17272368 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,15292727 0,17264387 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,15292727 0,17256412 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,15292727 0,17248446 ! sister chromatid segregation GO:0000819 65 37 0,000 0,15292727 0,17240486 ! odontogenesis GO:0042476 74 37 0,000 0,15292727 0,17232534 ! cell junction organization GO:0034330 96 37 0,000 0,15292727 0,17224589 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,15292727 0,17216651 ! female gonad development GO:0008585 71 37 0,000 0,15292727 0,17208721 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,15292727 0,17200798 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,15292727 0,17192882 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,15672046 0,17611227 ! meiosis I GO:0007127 74 38 0,000 0,15672046 0,1760313 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,15672046 0,1759504 ! organic anion transport GO:0015711 82 38 0,000 0,15672046 0,17586958 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,15672046 0,17578883 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,15672046 0,17570816 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,15672046 0,17562756 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,15672046 0,17554703 ! spermatid development GO:0007286 69 38 0,000 0,15672046 0,17546658 ! pigment metabolic process GO:0042440 87 38 0,000 0,15672046 0,1753862 ! neural tube formation GO:0001841 79 38 0,000 0,15672046 0,1753059 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,16049676 0,17944787 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,16049676 0,17936578 ! negative regulation of binding GO:0051100 71 39 0,000 0,16049676 0,17928376 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,16049676 0,17920182 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,16049676 0,17911996 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,16049676 0,17903817 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,16049676 0,17895645 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,16049676 0,17887481 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,16425626 0,18298132 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,16425626 0,18289792 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,16425626 0,1828146 ! mismatch repair GO:0006298 58 40 0,000 0,16425626 0,18273135 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,16425626 0,18264818 ! RNA export from nucleus GO:0006405 61 41 0,000 0,16799903 0,18672504 ! mRNA catabolic process GO:0006402 79 41 0,000 0,16799903 0,18664012 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,16799903 0,18655529 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,16799903 0,18647053 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,16799903 0,18638584 ! gliogenesis GO:0042063 91 41 0,000 0,16799903 0,18630124 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,16799903 0,18621671 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,16799903 0,18613226 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,16799903 0,18604788 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,16799903 0,18596358 ! spermatid differentiation GO:0048515 73 41 0,000 0,16799903 0,18587936 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,16799903 0,18579521 ! RNA modification GO:0009451 64 41 0,000 0,16799903 0,18571114 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,17172514 0,18974424 ! ear morphogenesis GO:0042471 64 42 0,000 0,17172514 0,18965846 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,17172514 0,18957276 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,17172514 0,18948714 ! regulation of protein secretion GO:0050708 77 42 0,000 0,17172514 0,18940159 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,17172514 0,18931612 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,17172514 0,18923073 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,17543467 0,19323124 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,17543467 0,19314416 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,17543467 0,19305716 ! regulation of tube size GO:0035150 76 43 0,000 0,17543467 0,19297024 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,17543467 0,19288339 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,17543467 0,19279663 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,17543467 0,19270994 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,17543467 0,19262333 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,17543467 0,19253679 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,17543467 0,19245034 ! ion transmembrane transport GO:0034220 79 43 0,000 0,17543467 0,19236396 ! neuron migration GO:0001764 85 43 0,000 0,17543467 0,19227766 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,17912769 0,1962372 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,17912769 0,19614924 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,17912769 0,19606136 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,17912769 0,19597355 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,17912769 0,19588583 ! striated muscle contraction GO:0006941 85 44 0,000 0,17912769 0,19579819 ! phagocytosis GO:0006909 105 44 0,000 0,17912769 0,19571062 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,17912769 0,19562313 ! double-strand break repair GO:0006302 85 44 0,000 0,17912769 0,19553572 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,18280427 0,19945995 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,18280427 0,19937091 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,18280427 0,19928194 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,18280427 0,19919306 ! B cell differentiation GO:0030183 124 45 0,000 0,18280427 0,19910425 ! female gamete generation GO:0007292 71 45 0,000 0,18280427 0,19901552 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,18280427 0,19892688 ! polyol metabolic process GO:0019751 77 45 0,000 0,18280427 0,19883831 ! maintenance of location in cell GO:0051651 101 45 0,000 0,18280427 0,19874982 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,18646449 0,20263912 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,18646449 0,20254902 ! glycolysis GO:0006096 71 46 0,000 0,18646449 0,202459 ! leukocyte migration GO:0050900 75 46 0,000 0,18646449 0,20236906 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,18646449 0,2022792 ! pigmentation GO:0043473 103 46 0,000 0,18646449 0,20218942 ! neural tube development GO:0021915 91 47 0,000 0,19010842 0,20604919 ! positive regulation of defense response GO:0031349 88 48 0,000 0,19373613 0,20988796 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,19373613 0,20979493 ! mitochondrial transport GO:0006839 94 48 0,000 0,19373613 0,20970198 ! cellular component disassembly GO:0022411 89 48 0,000 0,19373613 0,20960911 ! endosome transport GO:0016197 127 48 0,000 0,19373613 0,20951632 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,19373613 0,20942361 ! male sex differentiation GO:0046661 93 48 0,000 0,19373613 0,20933099 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,19373613 0,20923844 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,19373613 0,20914598 ! methylation GO:0032259 97 48 0,000 0,19373613 0,2090536 ! response to calcium ion GO:0051592 94 49 0,000 0,19734769 0,21285669 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,19734769 0,21276275 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,19734769 0,2126689 ! JNK cascade GO:0007254 106 49 0,000 0,19734769 0,21257513 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,19734769 0,21248145 ! regulation of action potential GO:0001508 102 50 0,000 0,20094317 0,21625734 ! regulation of ion transport GO:0043269 86 50 0,000 0,20094317 0,21616212 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,20094317 0,21606698 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,20094317 0,21597192 ! regulation of ossification GO:0030278 123 50 0,000 0,20094317 0,21587694 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,20094317 0,21578205 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,20094317 0,21568725 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,20452265 0,21943295 ! peptide metabolic process GO:0006518 80 51 0,000 0,20452265 0,21933663 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,20452265 0,21924039 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,2080862 0,22296253 ! Notch signaling pathway GO:0007219 111 52 0,000 0,2080862 0,22286479 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,2080862 0,22276712 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,2080862 0,22266955 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,2080862 0,22257206 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,2080862 0,22247465 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,2080862 0,22237733 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,2080862 0,2222801 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,2080862 0,22218295 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,2080862 0,22208588 ! amino acid activation GO:0043038 98 52 0,000 0,2080862 0,2219889 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,21163388 0,22567506 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,21163388 0,2255766 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,21163388 0,22547822 ! synapse organization GO:0050808 102 53 0,000 0,21163388 0,22537993 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,21516577 0,22904138 ! regulation of translational initiation GO:0006446 87 54 0,000 0,21516577 0,22894162 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,21516577 0,22884195 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,21516577 0,22874237 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,21516577 0,22864287 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,21516577 0,22854346 ! regulation of cell shape GO:0008360 142 54 0,000 0,21516577 0,22844414 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,21516577 0,2283449 ! RNA catabolic process GO:0006401 103 55 0,000 0,21868193 0,23197566 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,21868193 0,23187498 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,21868193 0,23177438 ! cell recognition GO:0008037 98 55 0,000 0,21868193 0,23167387 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,22218244 0,23528032 ! glucose catabolic process GO:0006007 88 56 0,000 0,22218244 0,23517838 ! RNA elongation GO:0006354 90 56 0,000 0,22218244 0,23507652 ! chloride transport GO:0006821 102 57 0,000 0,22566736 0,23866033 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,22566736 0,23855706 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,22566736 0,23845388 ! regulation of actin filament length GO:0030832 118 58 0,000 0,22913677 0,24201519 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,22913677 0,2419106 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,22913677 0,2418061 ! gastrulation GO:0007369 122 58 0,000 0,22913677 0,2417017 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,22913677 0,24159738 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,22913677 0,24149315 ! maintenance of location GO:0051235 124 58 0,000 0,22913677 0,24138902 ! nuclear export GO:0051168 110 59 0,000 0,23259073 0,24492205 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,23602931 0,24843585 ! DNA catabolic process GO:0006308 94 60 0,000 0,23602931 0,24832886 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,23602931 0,24822196 ! kidney development GO:0001822 133 60 0,000 0,23602931 0,24811515 ! regulation of cellular component size GO:0032535 125 61 0,000 0,23945258 0,25160545 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,23945258 0,25149728 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,23945258 0,2513892 ! regulation of heart contraction GO:0008016 123 61 0,000 0,23945258 0,25128121 ! camera-type eye development GO:0043010 126 61 0,000 0,23945258 0,25117332 ! proton transport GO:0015992 117 61 0,000 0,23945258 0,25106552 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,24286061 0,25452959 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,24286061 0,25442044 ! tRNA processing GO:0008033 102 62 0,000 0,24286061 0,25431139 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,24286061 0,25420243 ! mesoderm development GO:0007498 128 63 0,000 0,24625346 0,25764334 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,24625346 0,25753305 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,24625346 0,25742285 ! hydrogen transport GO:0006818 121 64 0,000 0,24963121 0,26084219 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,24963121 0,26073067 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,24963121 0,26061925 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,25299391 0,26401714 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,25299391 0,2639044 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,25299391 0,26379177 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,25299391 0,26367923 ! gonad development GO:0008406 115 66 0,000 0,25634163 0,26705442 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,25967445 0,2704112 ! chromosome segregation GO:0007059 127 67 0,000 0,25967445 0,27029599 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,25967445 0,27018087 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,25967445 0,27006585 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,26299242 0,27340021 ! hexose catabolic process GO:0019320 113 68 0,000 0,26299242 0,27328392 ! extracellular matrix organization GO:0030198 146 68 0,000 0,26299242 0,27316773 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,26299242 0,27305163 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,26299242 0,27293564 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,26629562 0,27624637 ! urogenital system development GO:0001655 149 69 0,000 0,26629562 0,27612912 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,26629562 0,27601196 ! single fertilization GO:0007338 83 69 0,000 0,26629562 0,27589491 ! cell redox homeostasis GO:0045454 114 70 0,000 0,26958411 0,27918354 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,27285794 0,28245422 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,27285794 0,28233459 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,27285794 0,28221505 ! B cell activation GO:0042113 179 72 0,000 0,2761172 0,28546522 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,2761172 0,28534447 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,2761172 0,28522381 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,2761172 0,28510326 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,2761172 0,28498281 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,27936194 0,28820997 ! amino acid transport GO:0006865 148 74 0,000 0,28259222 0,2914195 ! transition metal ion transport GO:0000041 143 75 0,000 0,28580812 0,29461149 ! reproductive structure development GO:0048608 131 75 0,000 0,28580812 0,29448724 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,28580812 0,29436308 ! eye development GO:0001654 155 75 0,000 0,28580812 0,29423904 ! axon guidance GO:0007411 162 75 0,000 0,28580812 0,29411509 ! rhythmic process GO:0048511 142 75 0,000 0,28580812 0,29399126 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,28900969 0,29715937 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,28900969 0,29703436 ! regulation of blood pressure GO:0008217 134 76 0,000 0,28900969 0,29690945 ! amine catabolic process GO:0009310 136 77 0,000 0,292197 0,3000577 ! neurotransmitter transport GO:0006836 142 77 0,000 0,292197 0,29993162 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,292197 0,29980566 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,292197 0,29967979 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,292197 0,29955404 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,29537011 0,30268002 ! antigen processing and presentation GO:0019882 117 78 0,000 0,29537011 0,30255311 ! fertilization GO:0009566 99 78 0,000 0,29537011 0,30242631 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,29852908 0,3055327 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,29852908 0,30540475 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,29852908 0,30527691 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,29852908 0,30514918 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,30167398 0,30823485 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,30167398 0,30810599 ! meiosis GO:0007126 143 81 0,000 0,30480487 0,31117355 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,30480487 0,31104357 ! meiotic cell cycle GO:0051321 144 82 0,000 0,30792181 0,3140931 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,31102486 0,31712593 ! exocytosis GO:0006887 153 83 0,000 0,31102486 0,31699363 ! response to drug GO:0042493 149 83 0,000 0,31102486 0,31686144 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,31102486 0,31672936 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,31102486 0,31659739 ! response to metal ion GO:0010038 158 84 0,000 0,31411409 0,31960879 ! response to nutrient GO:0007584 135 84 0,000 0,31411409 0,31947574 ! digestion GO:0007586 130 84 0,000 0,31411409 0,31934279 ! regulation of ligase activity GO:0051340 147 84 0,000 0,31411409 0,31920995 ! negative regulation of transport GO:0051051 164 85 0,000 0,31718955 0,32220128 ! negative regulation of growth GO:0045926 168 85 0,000 0,31718955 0,32206736 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,31718955 0,32193356 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,32025131 0,32490612 ! regulation of lyase activity GO:0051339 169 86 0,000 0,32025131 0,32477125 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,32329942 0,32772634 ! alcohol catabolic process GO:0046164 142 87 0,000 0,32329942 0,32759041 ! nucleosome assembly GO:0006334 126 87 0,000 0,32329942 0,3274546 ! cellular respiration GO:0045333 143 88 0,000 0,32633395 0,33039115 ! amine biosynthetic process GO:0009309 146 88 0,000 0,32633395 0,33025429 ! sensory perception of smell GO:0007608 117 88 0,000 0,32633395 0,33011753 ! chromatin assembly GO:0031497 128 88 0,000 0,32633395 0,3299809 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,32633395 0,32984437 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,32935496 0,3327602 ! tube morphogenesis GO:0035239 194 89 0,000 0,32935496 0,33262264 ! cellular defense response GO:0006968 123 89 0,000 0,32935496 0,3324852 ! response to inorganic substance GO:0010035 173 90 0,000 0,33236251 0,33538274 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,33236251 0,33524426 ! response to unfolded protein GO:0006986 139 90 0,000 0,33236251 0,33510591 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,33535665 0,33798527 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,33833745 0,34084882 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,33833745 0,34070832 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,34130497 0,34355502 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,34130497 0,34341352 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,34130497 0,34327214 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,34425926 0,34610097 ! female pregnancy GO:0007565 166 94 0,000 0,34425926 0,3459586 ! regulation of defense response GO:0031347 171 95 0,000 0,34720038 0,34877077 ! nucleosome organization GO:0034728 143 95 0,000 0,34720038 0,34862742 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,34720038 0,34848419 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,34720038 0,34834108 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,34720038 0,34819808 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,34720038 0,3480552 ! sex differentiation GO:0007548 171 96 0,000 0,35012839 0,35084646 ! response to protein stimulus GO:0051789 158 96 0,000 0,35012839 0,35070261 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,35304335 0,35347742 ! transcription initiation GO:0006352 171 97 0,000 0,35304335 0,35333262 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,35594532 0,35609108 ! mRNA transport GO:0051028 185 100 0,000 0,36171051 0,36171051