pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/502-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 9,000 8,186E-12 1,969E-08 ! apoptotic mitochondrial changes GO:0008637 41 20 6,000 5,748E-11 6,915E-08 ! regulation of lipid kinase activity GO:0043550 13 7 4,000 3,505E-10 2,811E-07 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 7,000 1,137E-09 6,837E-07 ! interphase of mitotic cell cycle GO:0051329 209 95 9,000 1,517E-09 7,299E-07 ! interphase GO:0051325 213 98 9,000 2,064E-09 8,277E-07 ! peptide or protein amino-terminal blocking GO:0018409 21 11 4,000 7,534E-09 2,59E-06 ! negative regulation of cell size GO:0045792 134 69 7,000 3,169E-08 9,53E-06 ! N-terminal protein amino acid modification GO:0031365 27 14 4,000 3,209E-08 8,579E-06 ! release of cytochrome c from mitochondria GO:0001836 30 14 4,000 3,209E-08 7,721E-06 ! N-terminal protein amino acid acetylation GO:0006474 13 7 3,000 8,373E-08 1,831E-05 ! response to UV GO:0009411 104 53 6,000 9,379E-08 1,881E-05 ! mitochondrion organization GO:0007005 148 86 7,000 1,814E-07 3,358E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 3,000 2,981E-07 5,123E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 4,867E-07 7,806E-05 ! negative regulation of cell growth GO:0030308 132 67 6,000 4,867E-07 7,318E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 3,000 4,941E-07 6,992E-05 ! activation of pro-apoptotic gene products GO:0008633 47 23 4,000 5,121E-07 6,845E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 5,393E-07 6,829E-05 ! cell cycle arrest GO:0007050 213 100 7,000 5,846E-07 7,033E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 8,001E-07 9,167E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 9,839E-07 1,076E-04 ! regulation of B cell proliferation GO:0030888 20 12 3,000 1,152E-06 1,205E-04 ! T cell homeostasis GO:0043029 25 12 3,000 1,152E-06 1,155E-04 ! protein amino acid acylation GO:0043543 55 27 4,000 1,201E-06 1,155E-04 ! negative regulation of growth GO:0045926 155 84 6,000 2,29E-06 2,119E-04 ! aging GO:0007568 103 55 5,000 2,532E-06 2,257E-04 ! lymphocyte homeostasis GO:0002260 30 15 3,000 3,123E-06 2,684E-04 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 3,452E-06 2,864E-04 ! B cell homeostasis GO:0001782 13 5 2,000 3,452E-06 2,768E-04 ! response to peptide hormone stimulus GO:0043434 122 61 5,000 4,682E-06 3,634E-04 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 3,000 5,386E-06 4,049E-04 ! regulation of protein stability GO:0031647 73 37 4,000 6,12E-06 4,462E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 6,12E-06 4,331E-04 ! nuclear migration GO:0007097 12 6 2,000 6,868E-06 4,721E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 6,868E-06 4,59E-04 GO:0031272|regulation of pseudopodium assembly, ! negative regulation of B cell activation GO:0050869 13 6 2,000 6,868E-06 4,466E-04 ! peptidyl-serine phosphorylation GO:0018105 38 18 3,000 6,886E-06 4,36E-04 ! G1 phase GO:0051318 40 19 3,000 8,674E-06 5,351E-04 ! protein amino acid acetylation GO:0006473 39 20 3,000 1,078E-05 6,486E-04 ! peptidyl-serine modification GO:0018209 43 20 3,000 1,078E-05 6,328E-04 ! macrophage differentiation GO:0030225 11 7 2,000 1,196E-05 6,849E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 1,196E-05 6,69E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 1,196E-05 6,538E-04 ! cell structure disassembly during apoptosis GO:0006921 30 21 3,000 1,325E-05 7,082E-04 ! cell aging GO:0007569 44 21 3,000 1,325E-05 6,928E-04 ! apoptotic nuclear changes GO:0030262 32 22 3,000 1,61E-05 8,242E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 1,638E-05 8,213E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 1,828E-05 8,974E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 1,903E-05 9,157E-04 ! ER overload response GO:0006983 12 8 2,000 1,903E-05 8,977E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,903E-05 8,805E-04 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 1,938E-05 8,798E-04 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell cycle GO:0045787 89 48 4,000 2,257E-05 1,006E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 3,000 2,313E-05 1,012E-03 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 2,313E-05 9,937E-04 ! leukocyte homeostasis GO:0001776 44 24 3,000 2,313E-05 9,763E-04 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 2,61E-05 1,083E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 2,738E-05 1,117E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 3,218E-05 1,291E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 3,757E-05 1,482E-03 ! protein sumoylation GO:0016925 15 10 2,000 4,035E-05 1,566E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 4,359E-05 1,665E-03 ! regulation of DNA replication GO:0006275 101 56 4,000 4,809E-05 1,808E-03 ! regulation of embryonic development GO:0045995 27 11 2,000 5,519E-05 2,043E-03 ! nucleus localization GO:0051647 19 11 2,000 5,519E-05 2,012E-03 ! transcription initiation GO:0006352 153 94 5,000 5,657E-05 2,032E-03 ! regulation of B cell activation GO:0050864 50 30 3,000 5,77E-05 2,042E-03 ! DNA catabolic process GO:0006308 86 59 4,000 6,196E-05 2,16E-03 ! leukocyte differentiation GO:0002521 202 96 5,000 6,366E-05 2,188E-03 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 6,747E-05 2,286E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 7,321E-05 2,446E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 7,321E-05 2,413E-03 ! focal adhesion formation GO:0048041 35 12 2,000 7,321E-05 2,38E-03 ! histone acetylation GO:0016573 26 12 2,000 7,321E-05 2,349E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 7,321E-05 2,318E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 7,321E-05 2,288E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of homeostatic process GO:0032844 134 62 4,000 7,872E-05 2,428E-03 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 8,502E-05 2,589E-03 ! homeostasis of number of cells GO:0048872 114 67 4,000 1,142E-04 3,434E-03 ! response to gamma radiation GO:0010332 28 14 2,000 1,199E-04 3,56E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 2,000 1,199E-04 3,517E-03 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 3,000 1,2E-04 3,478E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 1,313E-04 3,762E-03 ! nucleus organization GO:0006997 67 38 3,000 1,487E-04 4,209E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 2,000 1,825E-04 5,106E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,825E-04 5,047E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,825E-04 4,99E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of survival gene product expression GO:0045884 33 17 2,000 2,204E-04 5,959E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,204E-04 5,893E-03 ! microspike assembly GO:0030035 36 17 2,000 2,204E-04 5,828E-03 ! regulation of myeloid cell differentiation GO:0045637 98 42 3,000 2,205E-04 5,767E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 4,000 2,344E-04 6,063E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 2,632E-04 6,736E-03 ! protein import into nucleus GO:0006606 158 80 4,000 2,638E-04 6,682E-03 ! B cell differentiation GO:0030183 107 44 3,000 2,645E-04 6,63E-03 ! nuclear import GO:0051170 161 81 4,000 2,796E-04 6,935E-03 ! ATP synthesis coupled electron transport GO:0042773 64 45 3,000 2,887E-04 7,089E-03 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular pigmentation GO:0033059 36 19 2,000 3,109E-04 7,555E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 3,109E-04 7,48E-03 ! pigmentation GO:0043473 100 46 3,000 3,145E-04 7,492E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 3,638E-04 8,582E-03 ! response to alkaloid GO:0043279 38 20 2,000 3,638E-04 8,499E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,638E-04 8,417E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 3,638E-04 8,337E-03 ! oxidative phosphorylation GO:0006119 133 86 4,000 3,694E-04 8,384E-03 ! cellular component disassembly GO:0022411 86 48 3,000 3,709E-04 8,34E-03 ! activation of caspase activity GO:0006919 84 48 3,000 3,709E-04 8,262E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 3,709E-04 8,187E-03 ! protein localization in nucleus GO:0034504 176 87 4,000 3,896E-04 8,523E-03 ! regulation of cell adhesion GO:0030155 212 89 4,000 4,327E-04 9,38E-03 ! histone modification GO:0016570 91 50 3,000 4,342E-04 9,327E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 4,685E-04 9,976E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of intracellular transport GO:0032388 37 22 2,000 4,864E-04 0,01026538 ! protein stabilization GO:0050821 39 22 2,000 4,864E-04 0,01017611 ! protein maturation by protein folding GO:0022417 13 5 1,000 4,909E-04 0,01018234 ! positive regulation of glycolysis GO:0045821 14 5 1,000 4,909E-04 0,01009531 ! anagen GO:0042640 6 5 1,000 4,909E-04 0,01000976 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 4,909E-04 9,926E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 4,909E-04 9,843E-03 ! microvillus organization GO:0032528 7 5 1,000 4,909E-04 9,762E-03 GO:0030033|microvillus assembly, ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 4,909E-04 9,682E-03 ! response to food GO:0032094 6 5 1,000 4,909E-04 9,603E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 4,909E-04 9,525E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 4,909E-04 9,449E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 4,909E-04 9,374E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 4,909E-04 9,3E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 4,909E-04 9,228E-03 ! circadian behavior GO:0048512 13 5 1,000 4,909E-04 9,156E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 4,909E-04 9,086E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 4,909E-04 9,016E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 4,909E-04 8,948E-03 ! stem cell division GO:0017145 11 5 1,000 4,909E-04 8,881E-03 GO:0048103|somatic stem cell division, ! positive regulation of growth GO:0045927 90 52 3,000 5,048E-04 9,063E-03 ! covalent chromatin modification GO:0016569 101 52 3,000 5,048E-04 8,996E-03 ! respiratory electron transport chain GO:0022904 76 53 3,000 5,43E-04 9,606E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 5,564E-04 9,772E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 5,564E-04 9,701E-03 ! positive regulation of caspase activity GO:0043280 95 55 3,000 6,255E-04 0,01082651 GO:0010952|positive regulation of peptidase activity, ! protein import into nucleus, translocation GO:0000060 46 24 2,000 6,326E-04 0,01087216 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 6,326E-04 0,01079506 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 6,326E-04 0,01071904 ! protein tetramerization GO:0051262 52 24 2,000 6,326E-04 0,01064408 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 7,152E-04 0,01194916 ! interaction with host GO:0051701 62 25 2,000 7,152E-04 0,01186675 ! positive regulation of cell migration GO:0030335 126 57 3,000 7,165E-04 0,01180731 ! sleep GO:0030431 13 6 1,000 7,329E-04 0,01199636 ! protein lipoylation GO:0009249 10 6 1,000 7,329E-04 0,01191531 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 1,000 7,329E-04 0,01183534 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! neuron apoptosis GO:0051402 9 6 1,000 7,329E-04 0,01175643 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 7,329E-04 0,01167858 ! male sex determination GO:0030238 15 6 1,000 7,329E-04 0,01160174 ! establishment of spindle localization GO:0051293 12 6 1,000 7,329E-04 0,01152592 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 14 6 1,000 7,329E-04 0,01145107 ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 7,329E-04 0,01137719 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 7,329E-04 0,01130426 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 1,000 7,329E-04 0,01123226 ! hair follicle maturation GO:0048820 7 6 1,000 7,329E-04 0,01116117 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 7,329E-04 0,01109098 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 7,329E-04 0,01102166 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 7,329E-04 0,0109532 ! molting cycle process GO:0022404 50 26 2,000 8,042E-04 0,01194454 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! establishment of organelle localization GO:0051656 109 59 3,000 8,165E-04 0,01205199 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 8,7E-04 0,01276369 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 9,001E-04 0,01312481 ! mitochondrial membrane organization GO:0007006 57 27 2,000 9,001E-04 0,01304574 ! regulation of chromosome organization GO:0033044 42 27 2,000 9,001E-04 0,01296762 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 9,001E-04 0,01289043 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 1,000 1,021E-03 0,0145405 GO:0045346|regulation of MHC class II biosynthetic process, ! regulation of helicase activity GO:0051095 15 7 1,000 1,021E-03 0,01445497 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,021E-03 0,01437044 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 1,021E-03 0,01428689 GO:0031958|corticosteroid receptor signaling pathway, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,021E-03 0,01420431 ! rhythmic behavior GO:0007622 15 7 1,000 1,021E-03 0,01412267 ! protein-cofactor linkage GO:0018065 13 7 1,000 1,021E-03 0,01404197 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 1,021E-03 0,01396219 ! organ growth GO:0035265 15 7 1,000 1,021E-03 0,01388331 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,021E-03 0,01380531 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,021E-03 0,01372819 ! regulation of meiosis GO:0040020 12 7 1,000 1,021E-03 0,01365192 GO:0051445|regulation of meiotic cell cycle, ! response to tumor cell GO:0002347 13 7 1,000 1,021E-03 0,01357649 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,021E-03 0,0135019 ! peptidyl-threonine modification GO:0018210 25 7 1,000 1,021E-03 0,01342812 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 1,021E-03 0,01335514 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 1,045E-03 0,01359534 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,109E-03 0,01434465 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,113E-03 0,01431726 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,113E-03 0,01424111 ! myeloid cell differentiation GO:0030099 111 65 3,000 1,175E-03 0,01496021 ! cell junction assembly GO:0034329 78 30 2,000 1,23E-03 0,0155757 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 1,23E-03 0,01549416 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 1,23E-03 0,01541346 ! response to heat GO:0009408 50 30 2,000 1,23E-03 0,01533359 ! actin filament organization GO:0007015 148 66 3,000 1,244E-03 0,01542992 ! cell projection assembly GO:0030031 120 66 3,000 1,244E-03 0,01535079 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 1,355E-03 0,01662998 GO:0043433|negative regulation of transcription factor activity, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,355E-03 0,01655431 ! pigment granule organization GO:0048753 16 8 1,000 1,355E-03 0,0164707 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,355E-03 0,01638794 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,355E-03 0,016306 ! melanin metabolic process GO:0006582 15 8 1,000 1,355E-03 0,01622487 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,355E-03 0,01614455 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 1,355E-03 0,01606502 ! response to UV-B GO:0010224 16 8 1,000 1,355E-03 0,01598627 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,355E-03 0,01590829 ! regulation of circadian rhythm GO:0042752 16 8 1,000 1,355E-03 0,01583106 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 1,355E-03 0,01575458 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,355E-03 0,01567884 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,355E-03 0,01560382 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 1,39E-03 0,01593082 ! response to ionizing radiation GO:0010212 65 32 2,000 1,487E-03 0,01695747 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,487E-03 0,01687749 ! B cell activation GO:0042113 160 71 3,000 1,632E-03 0,01843311 ! regulation of caspase activity GO:0043281 122 72 3,000 1,718E-03 0,0193199 ! regulation of developmental growth GO:0048638 15 9 1,000 1,735E-03 0,0194114 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,735E-03 0,01932153 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 1,735E-03 0,01923249 ! regulation of glycolysis GO:0006110 21 9 1,000 1,735E-03 0,01914427 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,735E-03 0,01905685 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,735E-03 0,01897023 ! T cell selection GO:0045058 23 9 1,000 1,735E-03 0,01888439 ! receptor clustering GO:0043113 18 9 1,000 1,735E-03 0,01879933 ! behavioral fear response GO:0001662 22 9 1,000 1,735E-03 0,01871503 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 16 9 1,000 1,735E-03 0,01863148 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,735E-03 0,01854867 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,735E-03 0,0184666 ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 1,735E-03 0,01838525 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,735E-03 0,01830461 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,735E-03 0,01822468 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,735E-03 0,01814544 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 1,776E-03 0,01849402 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,776E-03 0,0184143 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,901E-03 0,01962934 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,901E-03 0,01954545 ! organelle localization GO:0051640 136 74 3,000 1,901E-03 0,01946228 ! regulation of muscle development GO:0048634 70 35 2,000 1,932E-03 0,01969679 ! cell-matrix adhesion GO:0007160 163 75 3,000 1,997E-03 0,02027378 ! lymphocyte differentiation GO:0030098 167 75 3,000 1,997E-03 0,02018859 ! regulation of catabolic process GO:0009894 161 76 3,000 2,096E-03 0,021105 ! mitotic sister chromatid segregation GO:0000070 57 36 2,000 2,097E-03 0,02101994 ! cell junction organization GO:0034330 86 36 2,000 2,097E-03 0,02093272 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 2,097E-03 0,02084622 ! negative regulation of cell activation GO:0050866 65 36 2,000 2,097E-03 0,02076044 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,158E-03 0,02128091 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,158E-03 0,02119405 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 2,158E-03 0,0211079 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 2,158E-03 0,02102244 ! glucan biosynthetic process GO:0009250 14 10 1,000 2,158E-03 0,02093767 GO:0005978|glycogen biosynthetic process, ! B cell proliferation GO:0042100 18 10 1,000 2,158E-03 0,02085358 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,158E-03 0,02077017 ! alpha-beta T cell activation GO:0046631 23 10 1,000 2,158E-03 0,02068742 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 2,158E-03 0,02060533 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 1,000 2,158E-03 0,02052388 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 1,000 2,158E-03 0,02044308 ! apical protein localization GO:0045176 15 10 1,000 2,158E-03 0,02036291 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,158E-03 0,02028337 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 2,158E-03 0,02020445 ! response to nicotine GO:0035094 20 10 1,000 2,158E-03 0,02012613 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 2,27E-03 0,02108693 ! sister chromatid segregation GO:0000819 58 37 2,000 2,27E-03 0,02100583 ! negative regulation of DNA binding GO:0043392 68 37 2,000 2,27E-03 0,02092535 ! glycogen metabolic process GO:0005977 61 37 2,000 2,27E-03 0,02084548 ! regulation of peptidase activity GO:0052547 134 79 3,000 2,415E-03 0,02209452 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,452E-03 0,02234463 ! glucan metabolic process GO:0044042 62 38 2,000 2,452E-03 0,02226031 GO:0006073|cellular glucan metabolic process, ! negative regulation of muscle development GO:0048635 20 11 1,000 2,625E-03 0,02374786 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 2,625E-03 0,02365892 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,625E-03 0,02357064 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,625E-03 0,02348301 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,625E-03 0,02339604 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of intracellular pH GO:0051453 19 11 1,000 2,625E-03 0,02330971 ! negative regulation of ossification GO:0030279 26 11 1,000 2,625E-03 0,02322401 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 2,625E-03 0,02313894 ! DNA methylation GO:0006306 19 11 1,000 2,625E-03 0,02305449 GO:0006305|DNA alkylation, ! oocyte differentiation GO:0009994 18 11 1,000 2,625E-03 0,02297066 ! thymus development GO:0048538 27 11 1,000 2,625E-03 0,02288743 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 2,625E-03 0,0228048 ! sequestering of metal ion GO:0051238 14 11 1,000 2,625E-03 0,02272277 ! response to hypoxia GO:0001666 171 81 3,000 2,645E-03 0,0228113 ! cell-substrate adhesion GO:0031589 171 81 3,000 2,645E-03 0,02272983 ! response to drug GO:0042493 143 82 3,000 2,766E-03 0,02368043 ! negative regulation of binding GO:0051100 72 40 2,000 2,842E-03 0,02424641 ! response to oxygen levels GO:0070482 176 83 3,000 2,89E-03 0,02456877 ! regulation of T cell proliferation GO:0042129 71 41 2,000 3,05E-03 0,02584218 ! T cell differentiation GO:0030217 81 41 2,000 3,05E-03 0,0257515 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 3,136E-03 0,02638143 ! virus-host interaction GO:0019048 29 12 1,000 3,136E-03 0,02628951 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 3,136E-03 0,02619822 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 3,136E-03 0,02610757 ! asymmetric protein localization GO:0008105 20 12 1,000 3,136E-03 0,02601755 ! entry into host cell GO:0030260 32 12 1,000 3,136E-03 0,02592814 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 1,000 3,136E-03 0,02583934 ! regulation of phagocytosis GO:0050764 16 12 1,000 3,136E-03 0,02575116 ! gland morphogenesis GO:0022612 29 12 1,000 3,136E-03 0,02566357 ! spleen development GO:0048536 22 12 1,000 3,136E-03 0,02557657 ! digestive tract morphogenesis GO:0048546 26 12 1,000 3,136E-03 0,02549016 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! response to reactive oxygen species GO:0000302 67 42 2,000 3,268E-03 0,02647446 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 3,268E-03 0,02638562 ! energy reserve metabolic process GO:0006112 74 43 2,000 3,495E-03 0,02812374 ! glucose transport GO:0015758 65 43 2,000 3,495E-03 0,02803 ! cellular respiration GO:0045333 135 88 3,000 3,568E-03 0,02852193 ! regulation of DNA binding GO:0051101 155 88 3,000 3,568E-03 0,02842749 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 3,689E-03 0,0292921 ! response to X-ray GO:0010165 25 13 1,000 3,689E-03 0,02919575 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 3,689E-03 0,02910002 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,689E-03 0,02900493 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 3,689E-03 0,02891045 ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 3,689E-03 0,02881658 ! regulation of cellular pH GO:0030641 22 13 1,000 3,689E-03 0,02872332 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,689E-03 0,02863067 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 3,689E-03 0,02853861 ! hexose transport GO:0008645 67 44 2,000 3,731E-03 0,02877475 GO:0015749|monosaccharide transport, ! developmental growth GO:0048589 82 44 2,000 3,731E-03 0,02868282 ! regulation of cell cycle process GO:0010564 149 90 3,000 3,867E-03 0,02963358 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 4,233E-03 0,03233081 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,233E-03 0,0322285 ! positive regulation of protein transport GO:0051222 72 46 2,000 4,233E-03 0,03212683 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 4,284E-03 0,03241098 ! hair follicle morphogenesis GO:0031069 26 14 1,000 4,284E-03 0,03230938 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 4,284E-03 0,03220841 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 4,284E-03 0,03210808 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 4,284E-03 0,03200836 ! regulation of T cell activation GO:0050863 158 94 3,000 4,516E-03 0,03363799 ! mitochondrial transport GO:0006839 82 48 2,000 4,773E-03 0,03544603 ! positive regulation of immune response GO:0050778 156 96 3,000 4,866E-03 0,03602258 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 4,92E-03 0,03631032 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 4,92E-03 0,03619928 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 4,92E-03 0,03608892 ! G1/S transition checkpoint GO:0031575 40 15 1,000 4,92E-03 0,03597922 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 4,92E-03 0,0358702 ! histone deacetylation GO:0016575 20 15 1,000 4,92E-03 0,03576183 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 4,92E-03 0,03565411 ! regulation of protein localization GO:0032880 176 97 3,000 5,048E-03 0,03646981 ! response to temperature stimulus GO:0009266 76 49 2,000 5,058E-03 0,03643857 ! regulation of cell projection organization GO:0031344 121 50 2,000 5,354E-03 0,03844969 ! regulation of ossification GO:0030278 117 50 2,000 5,354E-03 0,03833525 ! negative regulation of immune system process GO:0002683 95 50 2,000 5,354E-03 0,0382215 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 5,597E-03 0,03983865 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 5,597E-03 0,03972113 ! intermediate filament-based process GO:0045103 32 16 1,000 5,597E-03 0,0396043 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,597E-03 0,03948816 ! DNA replication initiation GO:0006270 27 16 1,000 5,597E-03 0,0393727 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 5,597E-03 0,03925791 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 5,597E-03 0,03914379 ! defense response to virus GO:0051607 37 16 1,000 5,597E-03 0,03903033 ! response to estrogen stimulus GO:0043627 93 51 2,000 5,659E-03 0,03935038 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 2,000 5,659E-03 0,03923698 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 5,659E-03 0,03912423 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 6,3E-03 0,04343424 ! metencephalon development GO:0022037 30 17 1,000 6,313E-03 0,0434004 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 6,313E-03 0,04327675 ! signal complex assembly GO:0007172 41 17 1,000 6,313E-03 0,04315381 ! regulation of viral genome replication GO:0045069 28 17 1,000 6,313E-03 0,04303156 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 6,313E-03 0,04291 ! regulation of protein binding GO:0043393 33 17 1,000 6,313E-03 0,04278913 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 6,313E-03 0,04266893 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 6,313E-03 0,04254941 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 6,313E-03 0,04243056 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 6,983E-03 0,04680246 ! regulation of protein catabolic process GO:0042176 116 55 2,000 6,983E-03 0,04667245 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 6,983E-03 0,04654316 ! RNA elongation GO:0006354 79 55 2,000 6,983E-03 0,04641459 ! positive regulation of proteolysis GO:0045862 31 18 1,000 7,07E-03 0,04685885 ! epidermis morphogenesis GO:0048730 40 18 1,000 7,07E-03 0,04673012 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 7,07E-03 0,04660209 ! nucleotide-excision repair GO:0006289 83 56 2,000 7,341E-03 0,04825659 ! regulation of bone remodeling GO:0046850 137 57 2,000 7,709E-03 0,05053776 ! regulation of intracellular transport GO:0032386 101 57 2,000 7,709E-03 0,05040043 ! maintenance of location GO:0051235 118 57 2,000 7,709E-03 0,05026385 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 7,865E-03 0,05114302 ! mitotic chromosome condensation GO:0007076 34 19 1,000 7,865E-03 0,05100516 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 7,865E-03 0,05086805 ! cellular response to unfolded protein GO:0034620 33 19 1,000 7,865E-03 0,05073168 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 7,865E-03 0,05059603 ! protein export from nucleus GO:0006611 36 19 1,000 7,865E-03 0,05046111 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 7,865E-03 0,0503269 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 7,865E-03 0,05019341 ! regulation of tissue remodeling GO:0034103 140 58 2,000 8,088E-03 0,05147776 ! regulation of endocytosis GO:0030100 91 58 2,000 8,088E-03 0,05134194 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 8,698E-03 0,05507421 ! protein amino acid deacetylation GO:0006476 29 20 1,000 8,698E-03 0,05492966 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 8,698E-03 0,05478586 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 8,698E-03 0,05464282 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 8,698E-03 0,05450052 ! negative regulation of translation GO:0017148 29 20 1,000 8,698E-03 0,05435896 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 8,698E-03 0,05421813 ! regulation of protein complex assembly GO:0043254 117 61 2,000 9,289E-03 0,05774836 ! ovarian follicle development GO:0001541 35 21 1,000 9,57E-03 0,05934079 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 9,57E-03 0,05918824 ! cytolysis GO:0019835 24 21 1,000 9,57E-03 0,05903647 ! oogenesis GO:0048477 36 21 1,000 9,57E-03 0,05888548 ! DNA modification GO:0006304 34 21 1,000 9,57E-03 0,05873527 ! response to cytokine stimulus GO:0034097 63 21 1,000 9,57E-03 0,05858581 ! gut development GO:0048565 39 21 1,000 9,57E-03 0,05843712 ! ear development GO:0043583 103 62 2,000 9,711E-03 0,05915078 ! viral reproductive process GO:0022415 126 62 2,000 9,711E-03 0,05900141 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 0,01047781 0,06350031 ! regeneration GO:0031099 41 22 1,000 0,01047781 0,06334076 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 0,01047781 0,06318201 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 0,01047781 0,06302405 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 0,01047781 0,06286689 ! ureteric bud development GO:0001657 43 22 1,000 0,01047781 0,0627105 ! renal system process GO:0003014 41 22 1,000 0,01047781 0,06255489 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 0,01047781 0,06240005 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 0,01047781 0,06224598 ! positive regulation of B cell activation GO:0050871 38 22 1,000 0,01047781 0,06209266 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 0,01047781 0,0619401 ! germ cell development GO:0007281 118 65 2,000 0,01104408 0,0651276 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,01142271 0,06719568 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 0,01142271 0,06703179 ! response to ethanol GO:0045471 46 23 1,000 0,01142271 0,0668687 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 0,01142271 0,06670639 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! sex determination GO:0007530 47 23 1,000 0,01142271 0,06654488 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 0,01142271 0,06638414 ! regulation of viral reproduction GO:0050792 38 23 1,000 0,01142271 0,06622418 ! synaptic vesicle transport GO:0048489 46 23 1,000 0,01142271 0,06606498 ! negative regulation of catabolic process GO:0009895 50 23 1,000 0,01142271 0,06590656 ! chromosome segregation GO:0007059 113 67 2,000 0,01198863 0,06900632 ! activation of immune response GO:0002253 105 67 2,000 0,01198863 0,06884163 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 0,01240362 0,07105504 ! multicellular organismal response to stress GO:0033555 49 24 1,000 0,01240362 0,07088627 ! lymphocyte proliferation GO:0046651 48 24 1,000 0,01240362 0,07071829 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 0,01240362 0,07055111 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,01240362 0,07038471 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 0,01240362 0,0702191 ! viral reproduction GO:0016032 134 68 2,000 0,01247777 0,07047307 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01342001 0,07561721 ! negative regulation of DNA replication GO:0008156 42 25 1,000 0,01342001 0,07544053 ! receptor metabolic process GO:0043112 46 25 1,000 0,01342001 0,07526468 ! chromosome condensation GO:0030261 45 25 1,000 0,01342001 0,07508965 ! response to starvation GO:0042594 42 25 1,000 0,01342001 0,07491542 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01342001 0,07474201 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 0,01342001 0,07456939 ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01342001 0,07439758 ! neural tube closure GO:0001843 49 25 1,000 0,01342001 0,07422655 GO:0060606|tube closure, ! humoral immune response GO:0006959 109 71 2,000 0,01401316 0,07732949 ! initiation of viral infection GO:0019059 57 26 1,000 0,01447133 0,07967508 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 0,01447133 0,07949317 ! tube lumen formation GO:0035148 50 26 1,000 0,01447133 0,07931209 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01447133 0,07913184 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01447133 0,0789524 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01447133 0,07877378 ! response to estradiol stimulus GO:0032355 40 26 1,000 0,01447133 0,07859596 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01447133 0,07841894 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 0,01447133 0,07824272 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01447133 0,07806728 GO:0032943|mononuclear cell proliferation, ! carbohydrate transport GO:0008643 110 72 2,000 0,01454771 0,0783038 ! fat cell differentiation GO:0045444 50 27 1,000 0,01555703 0,08354956 ! male gonad development GO:0008584 44 27 1,000 0,01555703 0,08336348 ! response to toxin GO:0009636 47 27 1,000 0,01555703 0,08317823 ! primary neural tube formation GO:0014020 51 27 1,000 0,01555703 0,0829938 ! base-excision repair GO:0006284 41 27 1,000 0,01555703 0,08281018 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01555703 0,08262738 ! regulation of vesicle-mediated transport GO:0060627 119 75 2,000 0,01622006 0,08595917 ! rhythmic process GO:0048511 128 75 2,000 0,01622006 0,08577025 ! circadian rhythm GO:0007623 50 28 1,000 0,01667658 0,08799088 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 0,01667658 0,08779834 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01667658 0,08760664 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01739242 0,09116812 ! regulation of pH GO:0006885 43 29 1,000 0,01782945 0,09325578 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01782945 0,09305349 ! complement activation, classical pathway GO:0006958 48 29 1,000 0,01782945 0,09285207 ! immune response-activating signal transduction GO:0002757 47 29 1,000 0,01782945 0,09265153 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01782945 0,09245185 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01782945 0,09225303 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01782945 0,09205506 ! tissue homeostasis GO:0001894 48 29 1,000 0,01782945 0,09185794 GO:0048871|multicellular organismal homeostasis, ! response to steroid hormone stimulus GO:0048545 137 78 2,000 0,0179959 0,09251739 ! protein oligomerization GO:0051259 139 78 2,000 0,0179959 0,09232012 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,01901513 0,09734126 ! response to metal ion GO:0010038 140 80 2,000 0,01923752 0,09827066 ! T cell activation GO:0042110 168 81 2,000 0,01987569 0,10131549 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01987569 0,10110129 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,02023308 0,10270211 ! ovulation cycle process GO:0022602 49 31 1,000 0,02023308 0,1024859 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 0,02023308 0,10227059 ! iron ion homeostasis GO:0055072 54 31 1,000 0,02023308 0,10205618 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,02023308 0,10184268 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,02023308 0,10163006 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,02148281 0,10768261 ! spindle organization GO:0007051 46 32 1,000 0,02148281 0,10745874 ! metanephros development GO:0001656 74 32 1,000 0,02148281 0,10723579 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,02148281 0,10701377 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,02148281 0,10679267 ! ovulation cycle GO:0042698 51 32 1,000 0,02148281 0,10657248 ! hindbrain development GO:0030902 61 32 1,000 0,02148281 0,10635319 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,02254422 0,11137861 GO:0002696|positive regulation of leukocyte activation, ! DNA damage checkpoint GO:0000077 71 33 1,000 0,02276381 0,11223305 ! post-embryonic development GO:0009791 69 33 1,000 0,02276381 0,11200354 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,02276381 0,11177496 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,02276381 0,11154731 ! response to inorganic substance GO:0010035 153 86 2,000 0,02324033 0,11365087 ! tube morphogenesis GO:0035239 176 86 2,000 0,02324033 0,11342034 ! regulation of protein transport GO:0051223 154 87 2,000 0,02394803 0,11663757 GO:0070201|regulation of establishment of protein localization, ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,02407557 0,11702188 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,02407557 0,11678595 ! placenta development GO:0001890 53 34 1,000 0,02407557 0,11655097 ! gland development GO:0048732 206 88 2,000 0,02466732 0,11917583 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,02541761 0,12255464 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,02541761 0,12230953 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,02541761 0,1220654 ! female gonad development GO:0008585 58 35 1,000 0,02541761 0,12182224 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02541761 0,12158005 ! neural tube formation GO:0001841 67 35 1,000 0,02541761 0,12133882 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02678942 0,12763436 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02678942 0,12738211 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02678942 0,12713087 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,02678942 0,12688061 ! regulation of proteolysis GO:0030162 72 36 1,000 0,02678942 0,12663134 ! response to protein stimulus GO:0051789 149 91 2,000 0,02689463 0,12687938 ! meiosis I GO:0007127 65 37 1,000 0,02819053 0,13273273 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,02819053 0,13247349 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 1,000 0,02819053 0,13221526 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 1,000 0,02819053 0,13195803 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,02962047 0,13838221 GO:0006956|complement activation, ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02962047 0,13811403 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02962047 0,13784689 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02962047 0,13758077 GO:0046660|female sex differentiation, ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02962047 0,13731568 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02962047 0,13705162 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02962047 0,13678856 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,03107874 0,14324799 ! learning GO:0007612 77 39 1,000 0,03107874 0,14297409 ! ear morphogenesis GO:0042471 60 39 1,000 0,03107874 0,14270124 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,03107874 0,14242943 ! segmentation GO:0035282 67 39 1,000 0,03107874 0,14215865 ! ion transmembrane transport GO:0034220 66 39 1,000 0,03107874 0,1418889 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,03107874 0,14162017 ! feeding behavior GO:0007631 59 40 1,000 0,03256489 0,14811178 ! mesenchymal cell development GO:0014031 87 40 1,000 0,03256489 0,14783233 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,03256489 0,14755392 ! cytokinesis GO:0000910 72 40 1,000 0,03256489 0,14727657 ! gliogenesis GO:0042063 88 41 1,000 0,03407846 0,15383259 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,03407846 0,15354452 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,03407846 0,15325752 ! female gamete generation GO:0007292 61 41 1,000 0,03407846 0,15297159 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0348677 0,1562229 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0348677 0,15593252 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0348677 0,15564322 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0348677 0,155355 ! neuron fate determination GO:0048664 7 5 0,000 0,0348677 0,15506783 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0348677 0,15478173 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0348677 0,15449668 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0348677 0,15421268 ! polyol transport GO:0015791 12 5 0,000 0,0348677 0,15392972 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0348677 0,1536478 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0348677 0,15336691 ! response to superoxide GO:0000303 10 5 0,000 0,0348677 0,15308704 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0348677 0,15280819 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0348677 0,15253036 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0348677 0,15225354 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0348677 0,15197771 ! female meiosis GO:0007143 7 5 0,000 0,0348677 0,15170289 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0348677 0,15142906 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0348677 0,15115621 ! cobalt ion transport GO:0006824 11 5 0,000 0,0348677 0,15088435 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0348677 0,15061346 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0348677 0,15034354 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0348677 0,15007459 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0348677 0,1498066 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0348677 0,14953957 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0348677 0,14927348 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0348677 0,14900834 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0348677 0,14874415 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0348677 0,14848088 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0348677 0,14821855 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0348677 0,14795714 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0348677 0,14769665 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0348677 0,14743708 ! negative chemotaxis GO:0050919 14 5 0,000 0,0348677 0,14717842 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0348677 0,14692066 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0348677 0,14666381 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0348677 0,14640785 ! behavioral response to pain GO:0048266 9 5 0,000 0,0348677 0,14615278 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0348677 0,1458986 ! Notch receptor processing GO:0007220 8 5 0,000 0,0348677 0,14564531 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0348677 0,14539289 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0348677 0,14514135 ! micturition GO:0060073 9 5 0,000 0,0348677 0,14489067 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0348677 0,14464086 ! copulation GO:0007620 9 5 0,000 0,0348677 0,14439191 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0348677 0,14414381 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0348677 0,14389657 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0348677 0,14365017 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0348677 0,14340461 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0348677 0,14315989 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0348677 0,14291601 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0348677 0,14267296 ! grooming behavior GO:0007625 6 5 0,000 0,0348677 0,14243073 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0348677 0,14218932 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0348677 0,14194873 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0348677 0,14170895 ! response to protozoan GO:0001562 10 5 0,000 0,0348677 0,14146998 ! lymph vessel development GO:0001945 10 5 0,000 0,0348677 0,14123181 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0348677 0,14099445 ! endochondral ossification GO:0001958 16 5 0,000 0,0348677 0,14075788 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0348677 0,14052211 ! parathyroid gland development GO:0060017 13 5 0,000 0,0348677 0,14028712 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0348677 0,14005292 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0348677 0,1398195 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0348677 0,13958685 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0348677 0,13935498 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0348677 0,13912388 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0348677 0,13889354 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0348677 0,13866396 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0348677 0,13843514 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0348677 0,13820708 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0348677 0,13797977 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0348677 0,1377532 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0348677 0,13752737 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0348677 0,13730229 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0348677 0,13707794 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0348677 0,13685432 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0348677 0,13663143 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0348677 0,13640926 ! histidine catabolic process GO:0006548 6 5 0,000 0,0348677 0,13618782 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0348677 0,1359671 ! valine metabolic process GO:0006573 10 5 0,000 0,0348677 0,13574708 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0348677 0,13552778 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0348677 0,13530919 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0348677 0,1350913 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0348677 0,13487411 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0348677 0,13465762 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0348677 0,13444182 ! polyol catabolic process GO:0046174 7 5 0,000 0,0348677 0,13422672 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0348677 0,1340123 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0348677 0,13379856 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0348677 0,13358551 ! muscle cell migration GO:0014812 8 5 0,000 0,0348677 0,13337313 ! mitochondrial fission GO:0000266 8 5 0,000 0,0348677 0,13316143 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0348677 0,13295039 ! mRNA transcription GO:0009299 9 5 0,000 0,0348677 0,13274003 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0348677 0,13253033 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0348677 0,13232129 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0348677 0,13211291 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0348677 0,13190519 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0348677 0,13169811 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0348677 0,13149169 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0348677 0,13128591 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0348677 0,13108078 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0348677 0,13087628 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0348677 0,13067243 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0348677 0,1304692 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,0348677 0,13026661 ! forebrain neuron development GO:0021884 13 5 0,000 0,0348677 0,13006465 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0348677 0,12986331 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0348677 0,12966259 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0348677 0,1294625 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0348677 0,12926302 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0348677 0,12906415 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0348677 0,1288659 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0348677 0,12866825 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0348677 0,12847121 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0348677 0,12827477 ! basic amino acid transport GO:0015802 11 5 0,000 0,0348677 0,12807893 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0348677 0,12788369 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0348677 0,12768904 ! depyrimidination GO:0045008 10 5 0,000 0,0348677 0,12749498 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0348677 0,12730151 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0348677 0,12710863 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0348677 0,12691634 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0348677 0,12672462 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0348677 0,12653348 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0348677 0,12634292 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0348677 0,12615293 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0348677 0,12596351 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0348677 0,12577466 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0348677 0,12558637 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0348677 0,12539865 ! response to arsenic GO:0046685 10 5 0,000 0,0348677 0,12521149 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0348677 0,12502488 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0348677 0,12483884 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0348677 0,12465334 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0348677 0,12446839 ! response to cadmium ion GO:0046686 7 5 0,000 0,0348677 0,124284 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0348677 0,12410014 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0348677 0,12391684 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0348677 0,12373407 ! decidualization GO:0046697 11 5 0,000 0,0348677 0,12355184 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0348677 0,12337014 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0348677 0,12318898 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0348677 0,12300835 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0348677 0,12282825 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0348677 0,12264868 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0348677 0,12246963 ! neural tube patterning GO:0021532 7 5 0,000 0,0348677 0,1222911 ! embryonic cleavage GO:0040016 6 5 0,000 0,0348677 0,1221131 ! peroxisome fission GO:0016559 5 5 0,000 0,0348677 0,12193561 ! histone demethylation GO:0016577 10 5 0,000 0,0348677 0,12175863 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0348677 0,12158217 ! mitotic recombination GO:0006312 9 5 0,000 0,0348677 0,12140622 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0348677 0,12123078 ! metaphase plate congression GO:0051310 7 5 0,000 0,0348677 0,12105584 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0348677 0,12088141 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0348677 0,12070748 ! enteric nervous system development GO:0048484 8 5 0,000 0,0348677 0,12053405 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0348677 0,12036112 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0348677 0,12018868 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0348677 0,12001674 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0348677 0,11984528 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0348677 0,11967432 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0348677 0,11950384 ! plasminogen activation GO:0031639 5 5 0,000 0,0348677 0,11933385 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0348677 0,11916434 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0348677 0,11899532 ! metaphase GO:0051323 8 5 0,000 0,0348677 0,11882677 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0348677 0,1186587 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0348677 0,1184911 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0348677 0,11832397 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0348677 0,11815732 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0348677 0,11799114 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0348677 0,11782542 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0348677 0,11766017 ! response to redox state GO:0051775 5 5 0,000 0,0348677 0,11749538 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0348677 0,11733105 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0348677 0,11716718 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0348677 0,11700376 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0348677 0,1168408 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0348677 0,1166783 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0348677 0,11651625 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0348677 0,11635464 GO:0033015|tetrapyrrole catabolic process, ! striatum development GO:0021756 9 5 0,000 0,0348677 0,11619349 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0348677 0,11603278 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0348677 0,11587251 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0348677 0,11571269 ! glial cell migration GO:0008347 11 5 0,000 0,0348677 0,1155533 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0348677 0,11539436 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0348677 0,11523585 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0348677 0,11507777 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0348677 0,11492013 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0348677 0,11476292 ! neuroprotection GO:0043526 6 5 0,000 0,0348677 0,11460614 ! neural plate development GO:0001840 8 5 0,000 0,0348677 0,11444979 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0348677 0,11429387 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0348677 0,11413836 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0348677 0,11398329 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0348677 0,11382863 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0348677 0,11367439 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0348677 0,11352057 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0348677 0,11336716 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0348677 0,11321417 ! spindle assembly GO:0051225 6 5 0,000 0,0348677 0,11306159 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0348677 0,11290942 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0348677 0,11275766 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0348677 0,11260631 ! drug metabolic process GO:0017144 6 5 0,000 0,0348677 0,11245536 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0348677 0,11230482 ! organ regeneration GO:0031100 7 5 0,000 0,0348677 0,11215468 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0348677 0,11200494 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0348677 0,1118556 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0348677 0,11170665 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,03561898 0,11396179 ! neuron migration GO:0001764 79 42 1,000 0,03561898 0,11381045 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03561898 0,1136595 GO:0090047|positive regulation of transcription regulator activity, ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,037186 0,11850268 ! neural tube development GO:0021915 77 43 1,000 0,037186 0,11834593 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,037186 0,11818959 ! male sex differentiation GO:0046661 76 44 1,000 0,03877908 0,12309032 ! double-strand break repair GO:0006302 81 44 1,000 0,03877908 0,12292815 ! biopolymer methylation GO:0043414 84 44 1,000 0,03877908 0,1227664 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,03877908 0,12260508 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,03877908 0,12244418 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03877908 0,1222837 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,04039777 0,12722124 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,04039777 0,12705494 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,04039777 0,12688907 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04169466 0,13079184 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04169466 0,13062154 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04169466 0,13045168 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04169466 0,13028227 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04169466 0,13011329 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04169466 0,12994475 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04169466 0,12977664 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04169466 0,12960897 ! response to oxygen radical GO:0000305 11 6 0,000 0,04169466 0,12944173 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04169466 0,12927493 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,04169466 0,12910855 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04169466 0,1289426 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04169466 0,12877708 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04169466 0,12861198 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,04169466 0,1284473 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04169466 0,12828305 ! forebrain regionalization GO:0021871 8 6 0,000 0,04169466 0,12811921 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04169466 0,1279558 ! male meiosis GO:0007140 7 6 0,000 0,04169466 0,1277928 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04169466 0,12763021 ! response to zinc ion GO:0010043 9 6 0,000 0,04169466 0,12746804 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04169466 0,12730627 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,04169466 0,12714492 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,04169466 0,12698398 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04169466 0,12682344 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04169466 0,12666331 ! malate metabolic process GO:0006108 11 6 0,000 0,04169466 0,12650359 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04169466 0,12634426 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04169466 0,12618534 ! protein refolding GO:0042026 15 6 0,000 0,04169466 0,12602681 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,04169466 0,12586869 ! opsonization GO:0008228 8 6 0,000 0,04169466 0,12571096 ! mating behavior GO:0007617 7 6 0,000 0,04169466 0,12555362 ! neuron remodeling GO:0016322 15 6 0,000 0,04169466 0,12539668 ! erythrocyte maturation GO:0043249 7 6 0,000 0,04169466 0,12524013 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,04169466 0,12508397 ! equilibrioception GO:0050957 14 6 0,000 0,04169466 0,1249282 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04169466 0,12477282 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04169466 0,12461782 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04169466 0,12446321 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,04169466 0,12430898 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04169466 0,12415513 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04169466 0,12400166 ! toxin metabolic process GO:0009404 11 6 0,000 0,04169466 0,12384857 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04169466 0,12369586 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04169466 0,12354353 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,04169466 0,12339157 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,04169466 0,12323998 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04169466 0,12308877 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,04169466 0,12293792 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04169466 0,12278745 ! thymic T cell selection GO:0045061 12 6 0,000 0,04169466 0,12263734 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04169466 0,1224876 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,04169466 0,12233822 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04169466 0,12218921 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04169466 0,12204056 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,04169466 0,12189228 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,04169466 0,12174435 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,04169466 0,12159678 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04169466 0,12144957 ! hyperosmotic response GO:0006972 9 6 0,000 0,04169466 0,12130271 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04169466 0,12115621 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04169466 0,12101007 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04169466 0,12086427 ! urea metabolic process GO:0019627 7 6 0,000 0,04169466 0,12071883 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04169466 0,12057373 ! neutrophil activation GO:0042119 8 6 0,000 0,04169466 0,12042898 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04169466 0,12028459 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04169466 0,12014053 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04169466 0,11999682 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04169466 0,11985346 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04169466 0,11971043 ! nucleoside salvage GO:0043174 9 6 0,000 0,04169466 0,11956775 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04169466 0,11942541 ! T cell mediated immunity GO:0002456 16 6 0,000 0,04169466 0,11928341 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04169466 0,11914174 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,04169466 0,11900041 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04169466 0,11885941 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04169466 0,11871875 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04169466 0,11857842 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04169466 0,11843842 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04169466 0,11829876 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,04169466 0,11815942 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,04169466 0,11802041 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,04169466 0,11788172 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04169466 0,11774336 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,04169466 0,11760533 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,04169466 0,11746762 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,04169466 0,11733023 ! response to UV-C GO:0010225 11 6 0,000 0,04169466 0,11719316 ! astrocyte development GO:0014002 15 6 0,000 0,04169466 0,11705641 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04169466 0,11691998 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04169466 0,11678387 ! interaction with symbiont GO:0051702 13 6 0,000 0,04169466 0,11664807 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04169466 0,1165126 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04169466 0,11637743 ! response to copper ion GO:0046688 10 6 0,000 0,04169466 0,11624258 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04169466 0,11610804 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04169466 0,11597381 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04169466 0,11583989 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04169466 0,11570628 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04169466 0,11557298 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04169466 0,11543998 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04169466 0,11530729 ! Schwann cell development GO:0014044 15 6 0,000 0,04169466 0,11517491 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04169466 0,11504283 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04169466 0,11491105 ! subpallium development GO:0021544 10 6 0,000 0,04169466 0,11477957 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04169466 0,11464839 ! histone ubiquitination GO:0016574 8 6 0,000 0,04169466 0,11451752 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04169466 0,11438694 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04169466 0,11425666 ! G2 phase GO:0051319 16 6 0,000 0,04169466 0,11412667 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04169466 0,11399698 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04169466 0,11386759 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04169466 0,11373849 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04169466 0,11360968 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04169466 0,11348116 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04169466 0,11335293 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04169466 0,11322499 ! receptor internalization GO:0031623 10 6 0,000 0,04169466 0,11309734 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,04169466 0,11296998 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04169466 0,11284291 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,04169466 0,11271612 ! protein deubiquitination GO:0016579 14 6 0,000 0,04169466 0,11258961 ! protein destabilization GO:0031648 9 6 0,000 0,04169466 0,11246339 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04169466 0,11233745 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04169466 0,11221179 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,04169466 0,11208642 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04169466 0,11196132 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04169466 0,1118365 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04169466 0,11171196 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04169466 0,1115877 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04169466 0,11146372 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,04169466 0,11134 ! determination of adult lifespan GO:0008340 15 6 0,000 0,04169466 0,11121657 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,04169466 0,1110934 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04169466 0,11097051 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04169466 0,11084789 ! catecholamine transport GO:0051937 9 6 0,000 0,04169466 0,11072555 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04169466 0,11060347 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04169466 0,11048166 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04169466 0,11036011 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,04169466 0,11023884 ! maternal placenta development GO:0001893 12 6 0,000 0,04169466 0,11011783 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04169466 0,10999709 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04169466 0,10987661 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04169466 0,10975639 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04169466 0,10963644 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04169466 0,10951675 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04169466 0,10939732 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,04204163 0,11018753 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,04204163 0,11006763 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,04371023 0,11431175 ! response to calcium ion GO:0051592 81 47 1,000 0,04371023 0,11418763 ! endosome transport GO:0016197 108 47 1,000 0,04371023 0,11406378 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,04371023 0,1139402 ! methylation GO:0032259 90 47 1,000 0,04371023 0,11381689 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,04540314 0,11809724 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,04540314 0,11796971 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,04711994 0,12229835 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,04711994 0,12216656 ! peptide metabolic process GO:0006518 76 49 1,000 0,04711994 0,12203506 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,04711994 0,12190383 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,04711994 0,1217729 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,04711994 0,12164224 ! tRNA transcription GO:0009304 14 7 0,000 0,04847354 0,12500251 ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04847354 0,12486868 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04847354 0,12473513 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04847354 0,12460186 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04847354 0,12446888 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04847354 0,12433619 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04847354 0,12420377 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04847354 0,12407164 ! prostate gland development GO:0030850 13 7 0,000 0,04847354 0,12393979 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04847354 0,12380822 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04847354 0,12367693 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04847354 0,12354592 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04847354 0,12341518 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04847354 0,12328472 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04847354 0,12315453 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04847354 0,12302462 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04847354 0,12289499 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04847354 0,12276563 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04847354 0,12263653 ! glycolipid transport GO:0046836 10 7 0,000 0,04847354 0,12250771 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04847354 0,12237916 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04847354 0,12225088 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04847354 0,12212287 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04847354 0,12199513 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04847354 0,12186765 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04847354 0,12174044 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04847354 0,1216135 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04847354 0,12148682 ! mRNA stabilization GO:0048255 18 7 0,000 0,04847354 0,1213604 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04847354 0,12123425 ! fibril organization GO:0043206 16 7 0,000 0,04847354 0,12110835 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04847354 0,12098272 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04847354 0,12085735 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04847354 0,12073224 ! lipoprotein transport GO:0042953 14 7 0,000 0,04847354 0,12060739 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04847354 0,12048279 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04847354 0,12035846 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04847354 0,12023438 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04847354 0,12011055 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04847354 0,11998698 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04847354 0,11986366 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04847354 0,1197406 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04847354 0,11961779 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04847354 0,11949523 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04847354 0,11937292 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04847354 0,11925086 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04847354 0,11912905 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04847354 0,11900749 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04847354 0,11888618 ! spinal cord patterning GO:0021511 13 7 0,000 0,04847354 0,11876512 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04847354 0,1186443 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04847354 0,11852372 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04847354 0,1184034 ! adrenal gland development GO:0030325 17 7 0,000 0,04847354 0,11828331 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04847354 0,11816347 ! ovulation GO:0030728 9 7 0,000 0,04847354 0,11804387 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04847354 0,11792451 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04847354 0,1178054 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04847354 0,11768652 ! microtubule nucleation GO:0007020 20 7 0,000 0,04847354 0,11756789 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04847354 0,11744949 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04847354 0,11733133 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04847354 0,11721341 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04847354 0,11709573 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04847354 0,11697828 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04847354 0,11686107 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04847354 0,11674409 ! galactose metabolic process GO:0006012 13 7 0,000 0,04847354 0,11662734 ! vesicle fusion GO:0006906 17 7 0,000 0,04847354 0,11651083 ! response to dietary excess GO:0002021 8 7 0,000 0,04847354 0,11639456 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04847354 0,11627851 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04847354 0,11616269 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04847354 0,11604711 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04847354 0,11593175 ! purine salvage GO:0043101 10 7 0,000 0,04847354 0,11581663 ! nucleoside transport GO:0015858 8 7 0,000 0,04847354 0,11570173 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04847354 0,11558706 ! parturition GO:0007567 14 7 0,000 0,04847354 0,11547262 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04847354 0,1153584 ! rRNA modification GO:0000154 14 7 0,000 0,04847354 0,11524441 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04847354 0,11513065 ! spindle checkpoint GO:0031577 15 7 0,000 0,04847354 0,1150171 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04847354 0,11490379 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04847354 0,11479069 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04847354 0,11467782 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04847354 0,11456517 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04847354 0,11445274 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04847354 0,11434053 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04847354 0,11422854 ! fibrinolysis GO:0042730 10 7 0,000 0,04847354 0,11411678 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04847354 0,11400522 ! eating behavior GO:0042755 7 7 0,000 0,04847354 0,11389389 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04847354 0,11378277 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04847354 0,11367188 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04847354 0,11356119 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04847354 0,11345072 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04847354 0,11334047 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04847354 0,11323043 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04847354 0,11312061 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04847354 0,11301099 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04847354 0,11290159 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04847354 0,1127924 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04847354 0,11268342 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04847354 0,11257466 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04847354 0,1124661 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04847354 0,11235775 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04847354 0,11224961 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04847354 0,11214168 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04847354 0,11203395 ! transcription termination GO:0006353 13 7 0,000 0,04847354 0,11192643 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04847354 0,11181912 ! anaphase GO:0051322 17 7 0,000 0,04847354 0,11171202 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04847354 0,11160511 ! axonal fasciculation GO:0007413 18 7 0,000 0,04847354 0,11149842 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04847354 0,11139192 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04847354 0,11128563 ! diuresis GO:0030146 12 7 0,000 0,04847354 0,11117955 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04847354 0,11107366 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04847354 0,11096798 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04847354 0,11086249 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04847354 0,11075721 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04847354 0,11065213 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04847354 0,11054725 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04847354 0,11044256 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04847354 0,11033807 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04847354 0,11023378 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04847354 0,11012969 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04847354 0,1100258 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04847354 0,1099221 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04847354 0,10981859 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04847354 0,10971528 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04847354 0,10961217 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04847354 0,10950924 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04847354 0,10940651 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04847354 0,10930398 ! adult feeding behavior GO:0008343 9 7 0,000 0,04847354 0,10920163 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04847354 0,10909948 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04847354 0,10899752 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04847354 0,10889575 ! muscle adaptation GO:0043500 14 7 0,000 0,04847354 0,10879416 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04847354 0,10869277 ! retina homeostasis GO:0001895 12 7 0,000 0,04847354 0,10859157 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04847354 0,10849055 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04847354 0,10838973 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04847354 0,10828908 ! protein prenylation GO:0018342 18 7 0,000 0,04847354 0,10818863 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04847354 0,10808836 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04847354 0,10798828 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04847354 0,10788839 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,0488602 0,10864847 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,0488602 0,10854815 ! positive regulation of binding GO:0051099 78 51 1,000 0,05062352 0,1123618 ! viral infectious cycle GO:0019058 99 51 1,000 0,05062352 0,11225824 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,05062352 0,11215487 ! vesicle organization GO:0016050 107 51 1,000 0,05062352 0,1120517 ! regulation of cell shape GO:0008360 125 51 1,000 0,05062352 0,11194871 ! membrane fusion GO:0006944 110 52 1,000 0,05240949 0,11579176 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,05240949 0,11568553 ! amino acid activation GO:0043038 92 52 1,000 0,05240949 0,11557949 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,05421769 0,11945766 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0552047 0,12152105 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0552047 0,12140997 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0552047 0,12129909 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0552047 0,12118842 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0552047 0,12107795 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0552047 0,12096768 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0552047 0,1208576 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0552047 0,12074773 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0552047 0,12063806 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0552047 0,12052859 ! meiotic prophase I GO:0007128 13 8 0,000 0,0552047 0,12041932 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0552047 0,12031024 ! oligopeptide transport GO:0006857 15 8 0,000 0,0552047 0,12020136 ! UTP metabolic process GO:0046051 8 8 0,000 0,0552047 0,12009268 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0552047 0,1199842 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0552047 0,11987591 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0552047 0,11976782 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0552047 0,11965992 ! succinate metabolic process GO:0006105 14 8 0,000 0,0552047 0,11955221 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0552047 0,1194447 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0552047 0,11933738 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0552047 0,11923026 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0552047 0,11912333 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0552047 0,11901658 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0552047 0,11891003 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0552047 0,11880367 ! reflex GO:0060004 16 8 0,000 0,0552047 0,1186975 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0552047 0,11859152 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0552047 0,11848573 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0552047 0,11838013 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0552047 0,11827472 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0552047 0,11816949 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0552047 0,11806445 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0552047 0,1179596 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0552047 0,11785493 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0552047 0,11775045 ! histidine metabolic process GO:0006547 16 8 0,000 0,0552047 0,11764615 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0552047 0,11754204 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0552047 0,11743811 ! glycine catabolic process GO:0006546 13 8 0,000 0,0552047 0,11733437 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0552047 0,11723081 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0552047 0,11712743 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0552047 0,11702424 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0552047 0,11692122 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0552047 0,11681839 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0552047 0,11671574 ! macrophage activation GO:0042116 12 8 0,000 0,0552047 0,11661326 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0552047 0,11651097 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0552047 0,11640886 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0552047 0,11630692 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0552047 0,11620517 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0552047 0,11610359 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0552047 0,11600219 ! osteoblast development GO:0002076 16 8 0,000 0,0552047 0,11590097 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0552047 0,11579992 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0552047 0,11569905 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0552047 0,11559835 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0552047 0,11549783 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0552047 0,11539749 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0552047 0,11529732 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0552047 0,11519732 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0552047 0,11509749 ! intermediate filament organization GO:0045109 12 8 0,000 0,0552047 0,11499784 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0552047 0,11489836 ! cellular extravasation GO:0045123 12 8 0,000 0,0552047 0,11479906 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0552047 0,11469992 ! response to antibiotic GO:0046677 11 8 0,000 0,0552047 0,11460096 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0552047 0,11450216 ! DNA topological change GO:0006265 12 8 0,000 0,0552047 0,11440354 ! response to tropane GO:0014073 15 8 0,000 0,0552047 0,11430508 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0552047 0,1142068 ! melanosome transport GO:0032402 13 8 0,000 0,0552047 0,11410868 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0552047 0,11401074 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0552047 0,11391296 ! mast cell activation GO:0045576 14 8 0,000 0,0552047 0,11381535 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0552047 0,1137179 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0552047 0,11362062 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0552047 0,11352351 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0552047 0,11342657 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0552047 0,11332978 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0552047 0,11323317 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0552047 0,11313672 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0552047 0,11304043 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0552047 0,11294431 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0552047 0,11284835 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0552047 0,11275255 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0552047 0,11265692 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0552047 0,11256145 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0552047 0,11246614 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0552047 0,11237099 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0552047 0,112276 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0552047 0,11218117 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0552047 0,1120865 ! hormone catabolic process GO:0042447 17 8 0,000 0,0552047 0,111992 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0552047 0,11189765 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0552047 0,11180346 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0552047 0,11170943 ! ATP catabolic process GO:0006200 11 8 0,000 0,0552047 0,11161555 ! blastocyst growth GO:0001832 19 8 0,000 0,0552047 0,11152184 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0552047 0,11142828 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0552047 0,11133488 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0552047 0,11124163 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0552047 0,11114854 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0552047 0,11105561 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0552047 0,11096283 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0552047 0,11087021 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0552047 0,11077774 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0552047 0,11068542 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0552047 0,11059326 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0552047 0,11050125 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0552047 0,1104094 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0552047 0,1103177 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0552047 0,11022615 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0552047 0,11013475 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0552047 0,1100435 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0552047 0,10995241 ! chloride transport GO:0006821 90 55 1,000 0,05789921 0,11522375 ! heart morphogenesis GO:0003007 97 55 1,000 0,05789921 0,11512852 ! nuclear export GO:0051168 97 55 1,000 0,05789921 0,11503345 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,05789921 0,11493854 ! proton transport GO:0015992 94 56 1,000 0,05977175 0,11855798 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,05977175 0,11846032 ! axon extension GO:0048675 15 9 0,000 0,06188846 0,12255444 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,06188846 0,12245365 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,06188846 0,12235303 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,06188846 0,12225258 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06188846 0,12215229 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,06188846 0,12205216 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,06188846 0,1219522 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,06188846 0,12185241 ! phosphate transport GO:0006817 19 9 0,000 0,06188846 0,12175277 ! reproductive behavior GO:0019098 19 9 0,000 0,06188846 0,1216533 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06188846 0,12155399 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,06188846 0,12145484 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06188846 0,12135586 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,06188846 0,12125704 ! GTP metabolic process GO:0046039 9 9 0,000 0,06188846 0,12115837 ! RNA methylation GO:0001510 15 9 0,000 0,06188846 0,12105987 ! elastic fiber assembly GO:0048251 15 9 0,000 0,06188846 0,12096153 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,06188846 0,12086334 ! artery development GO:0060840 24 9 0,000 0,06188846 0,12076532 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,06188846 0,12066746 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,06188846 0,12056975 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,06188846 0,1204722 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,06188846 0,12037481 ! chemosensory behavior GO:0007635 20 9 0,000 0,06188846 0,12027758 ! microtubule bundle formation GO:0001578 21 9 0,000 0,06188846 0,1201805 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,06188846 0,12008358 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06188846 0,11998682 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,06188846 0,11989021 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,06188846 0,11979376 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06188846 0,11969746 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06188846 0,11960132 ! protein targeting to ER GO:0045047 22 9 0,000 0,06188846 0,11950533 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,06188846 0,11940949 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,06188846 0,11931381 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,06188846 0,11921829 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06188846 0,11912291 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,06188846 0,11902769 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06188846 0,11893262 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06188846 0,1188377 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06188846 0,11874293 ! mannose metabolic process GO:0006013 13 9 0,000 0,06188846 0,11864832 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,06188846 0,11855385 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,06188846 0,11845954 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,06188846 0,11836537 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,06188846 0,11827136 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06188846 0,11817749 ! ruffle organization GO:0031529 15 9 0,000 0,06188846 0,11808377 ! retinol metabolic process GO:0042572 18 9 0,000 0,06188846 0,11799021 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,06188846 0,11789679 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,06188846 0,11780351 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,06188846 0,11771039 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,06188846 0,11761741 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,06188846 0,11752458 ! oligodendrocyte development GO:0014003 10 9 0,000 0,06188846 0,11743189 ! segment specification GO:0007379 13 9 0,000 0,06188846 0,11733935 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06188846 0,11724696 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,06188846 0,11715471 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06188846 0,11706261 ! response to amine stimulus GO:0014075 13 9 0,000 0,06188846 0,11697065 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,06188846 0,11687884 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,06188846 0,11678717 ! erythrocyte development GO:0048821 15 9 0,000 0,06188846 0,11669564 ! gas homeostasis GO:0033483 16 9 0,000 0,06188846 0,11660426 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,06188846 0,11651302 ! renal water homeostasis GO:0003091 14 9 0,000 0,06188846 0,11642192 ! postreplication repair GO:0006301 22 9 0,000 0,06188846 0,11633097 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,06188846 0,11624016 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,06188846 0,11614949 ! icosanoid secretion GO:0032309 15 9 0,000 0,06188846 0,11605896 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,06188846 0,11596857 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06188846 0,11587832 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 15 9 0,000 0,06188846 0,11578821 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,06188846 0,11569824 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,06188846 0,11560842 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,06188846 0,11551873 ! sterol catabolic process GO:0016127 11 9 0,000 0,06188846 0,11542918 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06188846 0,11533977 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,06188846 0,1152505 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,06188846 0,11516136 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,06188846 0,11507236 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 0,000 0,06188846 0,11498351 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,06188846 0,11489478 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,06188846 0,1148062 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,06188846 0,11471775 ! purine base metabolic process GO:0006144 21 9 0,000 0,06188846 0,11462944 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,06188846 0,11454126 ! pigment granule transport GO:0051904 17 9 0,000 0,06188846 0,11445322 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,06188846 0,11436531 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,06188846 0,11427754 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06188846 0,11418991 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06188846 0,11410241 ! mitochondrion localization GO:0051646 15 9 0,000 0,06188846 0,11401504 ! hydrogen transport GO:0006818 97 58 1,000 0,06357843 0,11703879 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,06551181 0,12050567 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,06551181 0,12041361 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,06746472 0,12390848 ! kidney development GO:0001822 122 60 1,000 0,06746472 0,12381397 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06852516 0,12566428 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06852516 0,12556858 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06852516 0,12547301 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06852516 0,1253776 ! synapsis GO:0007129 13 10 0,000 0,06852516 0,12528232 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06852516 0,1251872 ! N-glycan processing GO:0006491 20 10 0,000 0,06852516 0,12509222 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06852516 0,12499738 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06852516 0,12490268 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06852516 0,12480813 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06852516 0,12471372 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06852516 0,12461946 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06852516 0,12452533 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06852516 0,12443135 ! androgen metabolic process GO:0008209 17 10 0,000 0,06852516 0,12433751 ! phospholipid efflux GO:0033700 16 10 0,000 0,06852516 0,12424381 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06852516 0,12415026 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06852516 0,12405684 ! lung alveolus development GO:0048286 26 10 0,000 0,06852516 0,12396356 ! pathogenesis GO:0009405 13 10 0,000 0,06852516 0,12387043 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06852516 0,12377743 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06852516 0,12368458 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06852516 0,12359186 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06852516 0,12349928 ! endoderm development GO:0007492 16 10 0,000 0,06852516 0,12340684 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06852516 0,12331454 ! arginine catabolic process GO:0006527 13 10 0,000 0,06852516 0,12322238 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06852516 0,12313035 ! proline metabolic process GO:0006560 13 10 0,000 0,06852516 0,12303846 ! L-serine metabolic process GO:0006563 18 10 0,000 0,06852516 0,12294671 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06852516 0,1228551 ! V(D)J recombination GO:0033151 28 10 0,000 0,06852516 0,12276362 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06852516 0,12267228 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06852516 0,12258107 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06852516 0,12249 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06852516 0,12239906 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06852516 0,12230826 ! multicellular organism growth GO:0035264 18 10 0,000 0,06852516 0,1222176 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06852516 0,12212707 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06852516 0,12203667 ! epithelial cell development GO:0002064 20 10 0,000 0,06852516 0,12194641 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06852516 0,12185627 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06852516 0,12176628 ! macroautophagy GO:0016236 17 10 0,000 0,06852516 0,12167641 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06852516 0,12158668 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06852516 0,12149708 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06852516 0,12140761 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06852516 0,12131828 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06852516 0,12122907 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06852516 0,12114 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06852516 0,12105106 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06852516 0,12096224 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06852516 0,12087356 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06852516 0,12078501 ! response to dsRNA GO:0043331 20 10 0,000 0,06852516 0,12069659 ! DNA ligation GO:0006266 19 10 0,000 0,06852516 0,1206083 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06852516 0,12052013 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06852516 0,1204321 ! melanosome localization GO:0032400 16 10 0,000 0,06852516 0,12034419 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06852516 0,12025641 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06852516 0,12016876 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06852516 0,12008124 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06852516 0,11999384 ! mRNA cleavage GO:0006379 17 10 0,000 0,06852516 0,11990657 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06852516 0,11981943 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06852516 0,11973242 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06852516 0,11964553 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06852516 0,11955877 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06852516 0,11947213 ! salivary gland development GO:0007431 27 10 0,000 0,06852516 0,11938562 ! prophase GO:0051324 15 10 0,000 0,06852516 0,11929923 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06852516 0,11921297 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06852516 0,11912683 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06852516 0,11904082 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,06852516 0,11895493 ! midbrain development GO:0030901 13 10 0,000 0,06852516 0,11886917 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06852516 0,11878353 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06852516 0,11869801 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06852516 0,11861262 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06852516 0,11852735 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06852516 0,1184422 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06852516 0,11835717 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06852516 0,11827227 ! detection of calcium ion GO:0005513 23 10 0,000 0,06852516 0,11818748 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06852516 0,11810282 ! blastocyst formation GO:0001825 17 10 0,000 0,06852516 0,11801828 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06852516 0,11793386 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06852516 0,11784956 ! activation of innate immune response GO:0002218 12 10 0,000 0,06852516 0,11776539 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06852516 0,11768133 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06852516 0,11759739 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06852516 0,11751357 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06852516 0,11742987 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06852516 0,11734629 ! localization within membrane GO:0051668 20 10 0,000 0,06852516 0,11726283 ! gonad development GO:0008406 98 62 1,000 0,07142765 0,1221428 ! regulation of mitosis GO:0007088 105 63 1,000 0,07343694 0,12548954 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,07343694 0,12540048 ! respiratory burst GO:0045730 17 11 0,000 0,07511513 0,12817518 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,07511513 0,12808434 ! neuron fate specification GO:0048665 17 11 0,000 0,07511513 0,12799363 ! telencephalon cell migration GO:0022029 20 11 0,000 0,07511513 0,12790304 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,07511513 0,12781259 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,07511513 0,12772226 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,07511513 0,12763206 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,07511513 0,12754199 ! response to pain GO:0048265 24 11 0,000 0,07511513 0,12745205 ! T cell proliferation GO:0042098 26 11 0,000 0,07511513 0,12736223 ! blood vessel remodeling GO:0001974 29 11 0,000 0,07511513 0,12727254 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,07511513 0,12718297 ! bone resorption GO:0045453 16 11 0,000 0,07511513 0,12709353 ! ventral spinal cord development GO:0021517 21 11 0,000 0,07511513 0,12700422 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07511513 0,12691503 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07511513 0,12682597 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,07511513 0,12673703 ! melanocyte differentiation GO:0030318 21 11 0,000 0,07511513 0,12664821 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,07511513 0,12655952 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,07511513 0,12647096 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,07511513 0,12638252 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,07511513 0,1262942 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,07511513 0,12620601 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,07511513 0,12611793 ! UV protection GO:0009650 19 11 0,000 0,07511513 0,12602999 ! adult heart development GO:0007512 14 11 0,000 0,07511513 0,12594216 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,07511513 0,12585446 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07511513 0,12576688 ! temperature homeostasis GO:0001659 17 11 0,000 0,07511513 0,12567942 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,07511513 0,12559208 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,07511513 0,12550486 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,07511513 0,12541777 ! regulation of organ growth GO:0046620 13 11 0,000 0,07511513 0,12533079 ! pigment granule localization GO:0051875 20 11 0,000 0,07511513 0,12524394 ! vasoconstriction GO:0042310 18 11 0,000 0,07511513 0,1251572 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07511513 0,12507059 ! embryonic axis specification GO:0000578 18 11 0,000 0,07511513 0,12498409 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,07511513 0,12489772 ! snRNA metabolic process GO:0016073 24 11 0,000 0,07511513 0,12481146 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07511513 0,12472533 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,07511513 0,12463931 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,07511513 0,12455341 ! zymogen activation GO:0031638 15 11 0,000 0,07511513 0,12446763 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,07511513 0,12438197 ! neuroblast proliferation GO:0007405 24 11 0,000 0,07511513 0,12429642 ! nucleosome positioning GO:0016584 15 11 0,000 0,07511513 0,124211 ! regulation of isotype switching GO:0045191 22 11 0,000 0,07511513 0,12412569 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,07511513 0,12404049 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,07511513 0,12395542 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,07511513 0,12387046 ! acid secretion GO:0046717 18 11 0,000 0,07511513 0,12378562 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07511513 0,12370089 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,07511513 0,12361628 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,07511513 0,12353178 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,07511513 0,1234474 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,07511513 0,12336314 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,07511513 0,12327899 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,07511513 0,12319496 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07511513 0,12311104 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,07511513 0,12302723 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,07511513 0,12294354 ! embryonic gut development GO:0048566 15 11 0,000 0,07511513 0,12285996 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,07511513 0,12277649 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,07511513 0,12269314 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,07511513 0,12260991 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,07511513 0,12252678 ! defense response to fungus GO:0050832 13 11 0,000 0,07511513 0,12244377 ! developmental induction GO:0031128 19 11 0,000 0,07511513 0,12236087 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,07511513 0,12227808 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07511513 0,1221954 ! lamellipodium assembly GO:0030032 20 11 0,000 0,07511513 0,12211284 ! regulation of synapse organization GO:0050807 17 11 0,000 0,07511513 0,12203039 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,07546431 0,12251493 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,07546431 0,12243231 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,07546431 0,12234981 GO:0048609|reproductive process in a multicellular organism, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,07957185 0,12892247 ! secondary metabolic process GO:0019748 116 66 1,000 0,07957185 0,12883571 ! developmental maturation GO:0021700 116 66 1,000 0,07957185 0,12874907 ! activation of MAPK activity GO:0000187 115 67 1,000 0,08165133 0,13202494 ! lung development GO:0030324 144 67 1,000 0,08165133 0,13193627 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,08165133 0,13184772 ! adaptive immune response GO:0002250 119 67 1,000 0,08165133 0,13175929 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,08165869 0,13168285 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,08165869 0,13159465 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,08165869 0,13150657 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,08165869 0,1314186 ! cartilage condensation GO:0001502 20 12 0,000 0,08165869 0,13133076 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,08165869 0,13124303 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,08165869 0,13115541 ! protein complex disassembly GO:0043241 27 12 0,000 0,08165869 0,13106792 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,08165869 0,13098054 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,08165869 0,13089328 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,08165869 0,13080613 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,08165869 0,1307191 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,08165869 0,13063219 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,08165869 0,13054539 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,08165869 0,13045871 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,08165869 0,13037214 ! drug transport GO:0015893 16 12 0,000 0,08165869 0,13028568 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,08165869 0,13019934 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,08165869 0,13011312 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,08165869 0,13002701 ! polyamine metabolic process GO:0006595 17 12 0,000 0,08165869 0,12994101 ! mitotic spindle organization GO:0007052 21 12 0,000 0,08165869 0,12985513 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,08165869 0,12976936 ! forebrain cell migration GO:0021885 21 12 0,000 0,08165869 0,1296837 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,08165869 0,12959816 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,08165869 0,12951273 ! monoamine transport GO:0015844 18 12 0,000 0,08165869 0,12942741 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08165869 0,12934221 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,08165869 0,12925711 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,08165869 0,12917213 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,08165869 0,12908726 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,08165869 0,1290025 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,08165869 0,12891785 ! protein homotetramerization GO:0051289 21 12 0,000 0,08165869 0,12883332 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,08165869 0,12874889 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08165869 0,12866458 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,08165869 0,12858037 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,08165869 0,12849628 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,08165869 0,12841229 ! cranial nerve development GO:0021545 20 12 0,000 0,08165869 0,12832842 ! fucose catabolic process GO:0019317 22 12 0,000 0,08165869 0,12824465 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,08165869 0,128161 ! histone methylation GO:0016571 26 12 0,000 0,08165869 0,12807745 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,08165869 0,12799401 ! autonomic nervous system development GO:0048483 24 12 0,000 0,08165869 0,12791068 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,08165869 0,12782746 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,08165869 0,12774435 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,08165869 0,12766135 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,08165869 0,12757845 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,08165869 0,12749566 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,08165869 0,12741298 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,08165869 0,1273304 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,08165869 0,12724793 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,08165869 0,12716557 ! response to cold GO:0009409 17 12 0,000 0,08165869 0,12708332 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,08165869 0,12700117 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,08165869 0,12691913 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,0837475 0,13008166 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,0837475 0,12999774 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,08586002 0,13319098 ! urogenital system development GO:0001655 137 69 1,000 0,08586002 0,13310516 ! antigen processing and presentation GO:0019882 104 69 1,000 0,08586002 0,13301945 ! respiratory tube development GO:0030323 150 70 1,000 0,08798855 0,13622937 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08815617 0,13640113 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08815617 0,13631347 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08815617 0,13622592 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08815617 0,13613848 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,08815617 0,13605116 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08815617 0,13596394 ! lipid localization GO:0010876 28 13 0,000 0,08815617 0,13587684 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,08815617 0,13578985 ! organelle fusion GO:0048284 32 13 0,000 0,08815617 0,13570298 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,08815617 0,13561621 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,08815617 0,13552955 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,08815617 0,13544301 ! endocrine pancreas development GO:0031018 22 13 0,000 0,08815617 0,13535657 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08815617 0,13527025 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,08815617 0,13518404 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08815617 0,13509793 ! methionine metabolic process GO:0006555 27 13 0,000 0,08815617 0,13501194 ! plasma membrane organization GO:0007009 24 13 0,000 0,08815617 0,13492605 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,08815617 0,13484028 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08815617 0,13475461 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,08815617 0,13466905 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,08815617 0,1345836 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,08815617 0,13449826 ! cytokine metabolic process GO:0042107 22 13 0,000 0,08815617 0,13441302 ! exocrine system development GO:0035272 32 13 0,000 0,08815617 0,1343279 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08815617 0,13424288 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08815617 0,13415797 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,08815617 0,13407317 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,08815617 0,13398847 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,08815617 0,13390388 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,08815617 0,1338194 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08815617 0,13373503 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08815617 0,13365076 ! ribosome assembly GO:0042255 17 13 0,000 0,08815617 0,13356659 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08815617 0,13348254 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08815617 0,13339859 ! chromatin silencing GO:0006342 26 13 0,000 0,08815617 0,13331474 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,08815617 0,133231 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08815617 0,13314737 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08815617 0,13306383 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,08815617 0,13298041 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08815617 0,13289709 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,08815617 0,13281387 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08815617 0,13273076 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,08815617 0,13264775 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08815617 0,13256485 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,08815617 0,13248204 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08815617 0,13239935 ! embryonic placenta development GO:0001892 23 13 0,000 0,08815617 0,13231675 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,08815617 0,13223426 ! insulin secretion GO:0030073 23 13 0,000 0,08815617 0,13215187 ! actin filament polymerization GO:0030041 24 13 0,000 0,08815617 0,13206958 ! acrosome reaction GO:0007340 18 13 0,000 0,08815617 0,1319874 ! reproductive structure development GO:0048608 113 71 1,000 0,09013276 0,13486283 ! regulation of immune effector process GO:0002697 137 71 1,000 0,09013276 0,13477901 ! acute inflammatory response GO:0002526 113 72 1,000 0,09229233 0,13792258 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,09229233 0,13783697 ! respiratory system development GO:0060541 153 72 1,000 0,09229233 0,13775146 ! learning or memory GO:0007611 147 73 1,000 0,09446694 0,14090978 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,09446694 0,14082247 ! rRNA transcription GO:0009303 25 14 0,000 0,0946079 0,14094527 ! lactation GO:0007595 26 14 0,000 0,0946079 0,14085805 ! reproductive cellular process GO:0048610 20 14 0,000 0,0946079 0,14077094 ! tRNA modification GO:0006400 20 14 0,000 0,0946079 0,14068393 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0946079 0,14059704 ! regulation of S phase GO:0033261 23 14 0,000 0,0946079 0,14051025 ! water transport GO:0006833 21 14 0,000 0,0946079 0,14042357 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0946079 0,14033699 ! non-recombinational repair GO:0000726 25 14 0,000 0,0946079 0,14025053 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0946079 0,14016416 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0946079 0,14007791 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0946079 0,13999176 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0946079 0,13990572 ! palate development GO:0060021 31 14 0,000 0,0946079 0,13981978 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0946079 0,13973395 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0946079 0,13964822 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0946079 0,1395626 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0946079 0,13947709 ! arginine metabolic process GO:0006525 17 14 0,000 0,0946079 0,13939167 ! regulation of heart rate GO:0002027 24 14 0,000 0,0946079 0,13930637 ! organic alcohol transport GO:0015850 29 14 0,000 0,0946079 0,13922116 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0946079 0,13913607 ! embryo implantation GO:0007566 30 14 0,000 0,0946079 0,13905107 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0946079 0,13896618 ! L-amino acid transport GO:0015807 30 14 0,000 0,0946079 0,13888139 ! bone mineralization GO:0030282 17 14 0,000 0,0946079 0,13879671 ! stem cell development GO:0048864 43 14 0,000 0,0946079 0,13871213 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0946079 0,13862765 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0946079 0,13854328 ! cerebellum development GO:0021549 21 14 0,000 0,0946079 0,138459 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0946079 0,13837483 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0946079 0,13829077 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0946079 0,1382068 ! cofactor transport GO:0051181 26 14 0,000 0,0946079 0,13812294 ! NADP metabolic process GO:0006739 24 14 0,000 0,0946079 0,13803918 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0946079 0,13795552 ! intestinal absorption GO:0050892 25 14 0,000 0,0946079 0,13787196 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0946079 0,1377885 ! oxygen transport GO:0015671 21 14 0,000 0,0946079 0,13770514 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0946079 0,13762189 ! male genitalia development GO:0030539 24 14 0,000 0,0946079 0,13753873 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0946079 0,13745568 ! regulation of axon extension GO:0030516 37 14 0,000 0,0946079 0,13737272 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0946079 0,13728987 ! meiosis GO:0007126 121 74 1,000 0,09665627 0,14017781 GO:0051327|M phase of meiotic cell cycle, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,09665627 0,14009337 ! meiotic cell cycle GO:0051321 122 75 1,000 0,09886 0,14320119 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,10101419 0,14623353 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,10101419 0,1461456 ! superoxide anion generation GO:0042554 20 15 0,000 0,10101419 0,14605777 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,10101419 0,14597005 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,10101419 0,14588243 ! copper ion transport GO:0006825 20 15 0,000 0,10101419 0,14579492 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,10101419 0,14570751 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,10101419 0,14562021 ! sulfate transport GO:0008272 23 15 0,000 0,10101419 0,14553301 ! response to cAMP GO:0051591 22 15 0,000 0,10101419 0,14544592 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,10101419 0,14535893 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,10101419 0,14527205 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,10101419 0,14518527 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,10101419 0,14509859 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,10101419 0,14501201 ! response to hexose stimulus GO:0009746 22 15 0,000 0,10101419 0,14492554 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,10101419 0,14483917 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,10101419 0,14475291 ! pituitary gland development GO:0021983 29 15 0,000 0,10101419 0,14466675 ! vesicle coating GO:0006901 33 15 0,000 0,10101419 0,14458069 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,10101419 0,14449473 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,10101419 0,14440887 ! regulation of exocytosis GO:0017157 22 15 0,000 0,10101419 0,14432312 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,10101419 0,14423747 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,10101419 0,14415192 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,10101419 0,14406647 ! regulation of vasodilation GO:0042312 26 15 0,000 0,10101419 0,14398112 ! mRNA splice site selection GO:0006376 38 15 0,000 0,10101419 0,14389588 ! tissue regeneration GO:0042246 26 15 0,000 0,10101419 0,14381073 ! water homeostasis GO:0030104 27 15 0,000 0,10101419 0,14372569 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,10101419 0,14364074 ! muscle maintenance GO:0046716 26 15 0,000 0,10101419 0,1435559 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,10101419 0,14347115 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,10101419 0,14338651 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,10101419 0,14330197 ! dopamine metabolic process GO:0042417 35 15 0,000 0,10101419 0,14321752 ! heme biosynthetic process GO:0006783 29 15 0,000 0,10101419 0,14313318 ! cell killing GO:0001906 29 15 0,000 0,10101419 0,14304893 ! detection of bacterium GO:0016045 18 15 0,000 0,10101419 0,14296479 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,10101419 0,14288074 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,10101419 0,14279679 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,10101419 0,14271294 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,10101419 0,14262919 ! peptide hormone processing GO:0016486 23 15 0,000 0,10101419 0,14254553 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,10107783 0,14255173 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,10555453 0,14877809 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,10737536 0,15125592 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,10737536 0,15116742 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,10737536 0,15107901 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,10737536 0,15099071 ! bone remodeling GO:0046849 27 16 0,000 0,10737536 0,15090252 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,10737536 0,15081443 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,10737536 0,15072644 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,10737536 0,15063855 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,10737536 0,15055077 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,10737536 0,15046308 ! startle response GO:0001964 28 16 0,000 0,10737536 0,1503755 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,10737536 0,15028802 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,10737536 0,15020065 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,10737536 0,15011337 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,10737536 0,1500262 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,10737536 0,14993913 ! protein polyubiquitination GO:0000209 34 16 0,000 0,10737536 0,14985215 ! glutamate metabolic process GO:0006536 22 16 0,000 0,10737536 0,14976528 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,10737536 0,14967851 ! response to osmotic stress GO:0006970 25 16 0,000 0,10737536 0,14959184 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,10737536 0,14950527 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,10737536 0,1494188 ! fructose metabolic process GO:0006000 25 16 0,000 0,10737536 0,14933244 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10737536 0,14924617 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10737536 0,14916 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,10737536 0,14907393 ! negative regulation of immune response GO:0050777 35 16 0,000 0,10737536 0,14898795 ! axon cargo transport GO:0008088 43 16 0,000 0,10737536 0,14890208 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,10737536 0,14881631 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,10737536 0,14873063 ! neuron recognition GO:0008038 35 16 0,000 0,10737536 0,14864506 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,10737536 0,14855958 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,10737536 0,1484742 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,10737536 0,14838892 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,10737536 0,14830374 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,10737536 0,14821865 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,10737536 0,14813367 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,10737536 0,14804878 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10737536 0,14796398 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,10737536 0,14787929 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,10737536 0,14779469 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,10781281 0,14831196 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,10781281 0,14822721 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,10781281 0,14814256 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,10781281 0,148058 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,11008397 0,15109072 ! muscle cell differentiation GO:0042692 159 80 1,000 0,11008397 0,15100458 ! inorganic anion transport GO:0015698 138 80 1,000 0,11008397 0,15091854 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,11236772 0,1539617 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,11236772 0,15387407 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,11369173 0,15559858 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,11369173 0,15551012 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,11369173 0,15542176 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,11369173 0,1553335 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,11369173 0,15524535 ! endothelial cell migration GO:0043542 28 17 0,000 0,11369173 0,15515729 ! inositol metabolic process GO:0006020 28 17 0,000 0,11369173 0,15506933 ! gene silencing by RNA GO:0031047 36 17 0,000 0,11369173 0,15498147 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,11369173 0,15489371 ! glial cell development GO:0021782 27 17 0,000 0,11369173 0,15480605 ! limbic system development GO:0021761 36 17 0,000 0,11369173 0,15471849 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,11369173 0,15463103 ! adult walking behavior GO:0007628 33 17 0,000 0,11369173 0,15454367 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,11369173 0,15445641 ! heart looping GO:0001947 30 17 0,000 0,11369173 0,15436924 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,11369173 0,15428218 ! myoblast differentiation GO:0045445 45 17 0,000 0,11369173 0,15419521 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,11369173 0,15410834 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,11369173 0,15402156 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,11369173 0,15393489 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,11369173 0,15384831 ! glycine metabolic process GO:0006544 28 17 0,000 0,11369173 0,15376183 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,11369173 0,15367545 ! NAD metabolic process GO:0019674 29 17 0,000 0,11369173 0,15358916 ! membrane budding GO:0006900 37 17 0,000 0,11369173 0,15350297 ! DNA integration GO:0015074 29 17 0,000 0,11369173 0,15341688 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,11369173 0,15333088 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,11369173 0,15324499 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,11369173 0,15315918 ! genitalia development GO:0048806 30 17 0,000 0,11369173 0,15307347 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,11369173 0,15298786 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,11369173 0,15290235 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,11369173 0,15281693 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,11369173 0,1527316 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,11369173 0,15264637 ! steroid catabolic process GO:0006706 31 17 0,000 0,11369173 0,15256124 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,11369173 0,1524762 ! gas transport GO:0015669 25 17 0,000 0,11369173 0,15239125 ! organic cation transport GO:0015695 31 17 0,000 0,11369173 0,1523064 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,11369173 0,15222165 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,11369173 0,15213698 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,11369173 0,15205242 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,11466378 0,15326725 ! response to nutrient GO:0007584 125 82 1,000 0,11466378 0,15318215 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,11466378 0,15309715 ! regulation of lyase activity GO:0051339 160 83 1,000 0,11697185 0,15609223 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,11929166 0,15909964 ! negative regulation of transport GO:0051051 153 84 1,000 0,11929166 0,15901149 ! regulation of ligase activity GO:0051340 142 84 1,000 0,11929166 0,15892345 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,11929166 0,1588355 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,11996361 0,15964184 ! neuron maturation GO:0042551 42 18 0,000 0,11996361 0,15955359 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,11996361 0,15946544 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,11996361 0,15937739 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,11996361 0,15928943 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,11996361 0,15920157 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,11996361 0,15911381 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,11996361 0,15902614 ! memory GO:0007613 31 18 0,000 0,11996361 0,15893857 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11996361 0,1588511 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,11996361 0,15876372 ! patterning of blood vessels GO:0001569 39 18 0,000 0,11996361 0,15867644 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,11996361 0,15858926 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,11996361 0,15850217 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11996361 0,15841517 ! response to retinoic acid GO:0032526 26 18 0,000 0,11996361 0,15832828 ! response to fungus GO:0009620 21 18 0,000 0,11996361 0,15824147 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,11996361 0,15815477 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,11996361 0,15806815 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,11996361 0,15798164 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,11996361 0,15789521 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,11996361 0,15780888 ! vitamin transport GO:0051180 27 18 0,000 0,11996361 0,15772265 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,11996361 0,15763651 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,11996361 0,15755046 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,11996361 0,15746451 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,11996361 0,15737865 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,11996361 0,15729289 ! nerve development GO:0021675 28 18 0,000 0,11996361 0,15720722 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,11996361 0,15712164 ! response to unfolded protein GO:0006986 131 85 1,000 0,12162293 0,15920825 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,12162293 0,15912168 ! protein secretion GO:0009306 39 19 0,000 0,12619132 0,16500886 ! positive regulation of translation GO:0045727 30 19 0,000 0,12619132 0,16491923 ! negative regulation of defense response GO:0031348 25 19 0,000 0,12619132 0,1648297 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,12619132 0,16474027 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,12619132 0,16465093 ! skin development GO:0043588 36 19 0,000 0,12619132 0,16456169 ! lipid phosphorylation GO:0046834 35 19 0,000 0,12619132 0,16447254 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,12619132 0,16438349 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,12619132 0,16429454 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,12619132 0,16420568 ! bile acid metabolic process GO:0008206 29 19 0,000 0,12619132 0,16411692 ! cerebral cortex development GO:0021987 36 19 0,000 0,12619132 0,16402826 ! pigmentation during development GO:0048066 41 19 0,000 0,12619132 0,16393969 ! response to vitamin A GO:0033189 27 19 0,000 0,12619132 0,16385122 ! heme metabolic process GO:0042168 36 19 0,000 0,12619132 0,16376284 ! neuromuscular junction development GO:0007528 34 19 0,000 0,12619132 0,16367456 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,12619132 0,16358637 ! plasma membrane fusion GO:0045026 28 19 0,000 0,12619132 0,16349828 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,12619132 0,16341029 ! peptide cross-linking GO:0018149 37 19 0,000 0,12619132 0,16332238 ! heart process GO:0003015 30 19 0,000 0,12619132 0,16323458 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,12619132 0,16314686 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,12619132 0,16305924 ! cell-cell junction organization GO:0045216 35 19 0,000 0,12619132 0,16297172 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,12619132 0,16288429 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,12619132 0,16279695 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,12619132 0,16270971 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,12619132 0,16262256 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,12619132 0,1625355 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,12619132 0,16244853 ! cilium assembly GO:0042384 37 19 0,000 0,12619132 0,16236166 ! peptide hormone secretion GO:0030072 31 19 0,000 0,12619132 0,16227489 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,12631872 0,16235194 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,12868271 0,16530197 ! regulation of neurological system process GO:0031644 148 88 1,000 0,12868271 0,16521376 ! ATP biosynthetic process GO:0006754 159 88 1,000 0,12868271 0,16512565 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,13105706 0,16808278 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,13237516 0,16968281 ! positive regulation of ossification GO:0045778 47 20 0,000 0,13237516 0,16959246 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,13237516 0,1695022 ! cAMP metabolic process GO:0046058 36 20 0,000 0,13237516 0,16941204 ! response to vitamin GO:0033273 31 20 0,000 0,13237516 0,16932197 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,13237516 0,169232 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,13237516 0,16914213 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,13237516 0,16905235 ! retinoid metabolic process GO:0001523 32 20 0,000 0,13237516 0,16896267 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,13237516 0,16887308 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,13237516 0,16878359 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,13237516 0,16869419 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,13237516 0,16860489 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,13237516 0,16851568 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,13237516 0,16842656 ! body fluid secretion GO:0007589 31 20 0,000 0,13237516 0,16833754 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,13237516 0,16824862 ! peptide secretion GO:0002790 35 20 0,000 0,13237516 0,16815978 ! stem cell differentiation GO:0048863 53 20 0,000 0,13237516 0,16807105 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,13237516 0,1679824 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,13237516 0,16789385 ! sensory perception of pain GO:0019233 30 20 0,000 0,13237516 0,16780539 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,13237516 0,16771703 ! diencephalon development GO:0021536 34 20 0,000 0,13237516 0,16762875 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,13237516 0,16754057 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,13237516 0,16745249 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,13237516 0,16736449 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,13237516 0,16727659 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,13237516 0,16718878 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,13237516 0,16710107 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,13237516 0,16701344 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,13237516 0,16692591 ! regulation of glucose import GO:0046324 29 20 0,000 0,13237516 0,16683847 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,13237516 0,16675112 ! actin filament-based movement GO:0030048 43 20 0,000 0,13237516 0,16666386 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,13237516 0,16657669 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,13237516 0,16648961 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,13237516 0,16640263 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,13344153 0,16765552 ! sex differentiation GO:0007548 145 90 1,000 0,13344153 0,16756801 ! regulation of cell killing GO:0031341 42 21 0,000 0,13851544 0,1738488 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,13851544 0,17375816 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,13851544 0,17366761 ! hormone secretion GO:0046879 38 21 0,000 0,13851544 0,17357716 ! glycerol metabolic process GO:0006071 34 21 0,000 0,13851544 0,17348681 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,13851544 0,17339654 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,13851544 0,17330637 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,13851544 0,1732163 ! axis specification GO:0009798 38 21 0,000 0,13851544 0,17312631 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,13851544 0,17303642 ! smooth muscle contraction GO:0006939 46 21 0,000 0,13851544 0,17294663 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,13851544 0,17285693 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,13851544 0,17276732 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,13851544 0,1726778 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,13851544 0,17258838 ! vasodilation GO:0042311 39 21 0,000 0,13851544 0,17249904 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,13851544 0,1724098 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,13851544 0,17232066 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,13851544 0,1722316 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,13851544 0,17214264 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,13851544 0,17205377 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,13851544 0,17196499 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,13851544 0,1718763 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,13851544 0,17178771 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,13851544 0,1716992 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,13851544 0,17161079 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,13851544 0,17152247 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,13851544 0,17143424 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,13851544 0,17134609 ! collagen catabolic process GO:0030574 28 21 0,000 0,13851544 0,17125804 ! sperm-egg recognition GO:0035036 21 21 0,000 0,13851544 0,17117008 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,14065298 0,17372232 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,14065298 0,17363318 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,14065298 0,17354414 ! regulation of membrane potential GO:0042391 164 93 1,000 0,14065298 0,17345519 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,14065298 0,17336633 ! female pregnancy GO:0007565 164 94 1,000 0,14307531 0,17626175 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,14461247 0,17806428 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,14461247 0,1779732 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,14461247 0,17788221 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,14461247 0,17779132 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,14461247 0,17770051 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,14461247 0,1776098 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,14461247 0,17751919 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,14461247 0,17742866 ! keratinization GO:0031424 28 22 0,000 0,14461247 0,17733823 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,14461247 0,17724789 ! sensory perception of taste GO:0050909 28 22 0,000 0,14461247 0,17715764 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,14461247 0,17706748 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,14461247 0,17697742 ! vacuolar transport GO:0007034 36 22 0,000 0,14461247 0,17688745 ! lysosome organization GO:0007040 41 22 0,000 0,14461247 0,17679756 ! central nervous system neuron development GO:0021954 46 22 0,000 0,14461247 0,17670777 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,14461247 0,17661807 ! fucose metabolic process GO:0006004 39 22 0,000 0,14461247 0,17652847 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,14461247 0,17643895 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,14461247 0,17634952 GO:0060415|muscle tissue morphogenesis, ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,14461247 0,17626019 ! sarcomere organization GO:0045214 30 22 0,000 0,14461247 0,17617094 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,14461247 0,17608178 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,14461247 0,17599272 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,14461247 0,17590374 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,14461247 0,17581486 ! forebrain development GO:0030900 188 95 1,000 0,14550648 0,17681242 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,14550648 0,17672316 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 0,14794624 0,17959569 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 1,000 0,14794624 0,17950512 ! detection of stimulus GO:0051606 151 96 1,000 0,14794624 0,17941464 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,15039436 0,1822916 ! protein ubiquitination GO:0016567 217 97 1,000 0,15039436 0,18219981 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,15066655 0,18243771 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,15066655 0,18234594 ! gluconeogenesis GO:0006094 33 23 0,000 0,15066655 0,18225426 ! viral genome replication GO:0019079 41 23 0,000 0,15066655 0,18216268 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,15066655 0,18207118 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,15066655 0,18197978 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,15066655 0,18188847 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,15066655 0,18179725 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,15066655 0,18170613 ! visual behavior GO:0007632 42 23 0,000 0,15066655 0,18161509 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,15066655 0,18152415 ! peroxisome organization GO:0007031 37 23 0,000 0,15066655 0,1814333 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,15066655 0,18134253 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,15066655 0,18125186 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,15066655 0,18116128 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,15066655 0,18107079 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,15066655 0,18098039 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,15066655 0,18089008 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,15066655 0,18079986 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,15066655 0,18070973 ! fatty acid transport GO:0015908 44 23 0,000 0,15066655 0,18061969 ! platelet activation GO:0030168 37 23 0,000 0,15066655 0,18052974 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,15066655 0,18043988 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,15066655 0,18035011 ! hormone transport GO:0009914 40 23 0,000 0,15066655 0,18026043 ! cell-cell recognition GO:0009988 25 23 0,000 0,15066655 0,18017084 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,15066655 0,18008133 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,15066655 0,17999192 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,15066655 0,17990259 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,15066655 0,17981335 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,15285059 0,18232946 ! response to virus GO:0009615 160 98 1,000 0,15285059 0,1822391 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,1553147 0,18508527 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,1553147 0,18499365 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,1553147 0,18490211 GO:0060538|skeletal muscle organ development, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,15667798 0,18643285 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,15667798 0,1863407 ! vesicle docking GO:0048278 47 24 0,000 0,15667798 0,18624863 ! spinal cord development GO:0021510 47 24 0,000 0,15667798 0,18615666 ! vacuole organization GO:0007033 43 24 0,000 0,15667798 0,18606477 ! digestive system process GO:0022600 39 24 0,000 0,15667798 0,18597298 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,15667798 0,18588128 ! regulation of behavior GO:0050795 43 24 0,000 0,15667798 0,18578966 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,15667798 0,18569814 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,15667798 0,18560671 ! membrane depolarization GO:0051899 39 24 0,000 0,15667798 0,18551537 ! pallium development GO:0021543 49 24 0,000 0,15667798 0,18542412 ! pentose metabolic process GO:0019321 35 24 0,000 0,15667798 0,18533295 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,15667798 0,18524188 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,15667798 0,1851509 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,15667798 0,18506 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,15667798 0,1849692 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,15667798 0,18487848 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,15667798 0,18478786 ! regulation of amine transport GO:0051952 40 24 0,000 0,15667798 0,18469732 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,16264707 0,19163998 ! myelination GO:0042552 45 25 0,000 0,16264707 0,19154618 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,16264707 0,19145247 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,16264707 0,19135885 ! phototransduction GO:0007602 33 25 0,000 0,16264707 0,19126532 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,16264707 0,19117188 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,16264707 0,19107854 ! sperm motility GO:0030317 31 25 0,000 0,16264707 0,19098528 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,16264707 0,19089212 ! osteoblast differentiation GO:0001649 60 25 0,000 0,16264707 0,19079904 ! neural crest cell development GO:0014032 54 25 0,000 0,16264707 0,19070606 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,16264707 0,19061317 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,16264707 0,19052037 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,16264707 0,19042766 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,16264707 0,19033504 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,16264707 0,19024251 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,16264707 0,19015007 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,16264707 0,19005772 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,16264707 0,18996546 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,16264707 0,18987328 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,16264707 0,1897812 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,16264707 0,18968921 ! telomere organization GO:0032200 43 25 0,000 0,16264707 0,18959731 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,16264707 0,18950549 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,1685741 0,1963162 ! embryonic pattern specification GO:0009880 44 26 0,000 0,1685741 0,19622123 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,1685741 0,19612634 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,1685741 0,19603155 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,1685741 0,19593685 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,1685741 0,19584224 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,1685741 0,19574772 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,1685741 0,19565329 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,1685741 0,19555896 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,1685741 0,19546471 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,1685741 0,19537056 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,1685741 0,19527649 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,1685741 0,19518252 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,1685741 0,19508864 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,1685741 0,19499484 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,1685741 0,19490114 ! blastocyst development GO:0001824 49 26 0,000 0,1685741 0,19480753 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,1685741 0,19471401 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,1685741 0,19462057 ! neuron fate commitment GO:0048663 48 27 0,000 0,17445937 0,20131858 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,17445937 0,20122207 ! iron ion transport GO:0006826 59 27 0,000 0,17445937 0,20112565 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,17445937 0,20102933 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,17445937 0,2009331 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,17445937 0,20083696 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,17445937 0,20074091 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,17445937 0,20064495 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,17445937 0,20054909 ! autophagy GO:0006914 41 27 0,000 0,17445937 0,20045331 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,17445937 0,20035763 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,17445937 0,20026204 ! glutathione metabolic process GO:0006749 39 27 0,000 0,17445937 0,20016654 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,17445937 0,20007113 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,17445937 0,19997582 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,18030317 0,20657592 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,18030317 0,2064776 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,18030317 0,20637937 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,18030317 0,20628124 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,18030317 0,20618319 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,18030317 0,20608524 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,18030317 0,20598739 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,18030317 0,20588962 ! synaptogenesis GO:0007416 42 28 0,000 0,18030317 0,20579195 ! lipid oxidation GO:0034440 43 28 0,000 0,18030317 0,20569438 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,18030317 0,20559689 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,18030317 0,2054995 ! translational initiation GO:0006413 65 29 0,000 0,18610581 0,21201258 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,18610581 0,21191224 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,18610581 0,211812 ! catechol metabolic process GO:0009712 54 29 0,000 0,18610581 0,21171185 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,18610581 0,2116118 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,18610581 0,21151184 ! cell fate determination GO:0001709 60 29 0,000 0,18610581 0,21141198 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,18610581 0,21131221 ! detection of light stimulus GO:0009583 38 29 0,000 0,18610581 0,21121253 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,18610581 0,21111295 ! regulation of coagulation GO:0050818 46 29 0,000 0,18610581 0,21101346 ! phenol metabolic process GO:0018958 55 30 0,000 0,19186755 0,21744387 ! zinc ion transport GO:0006829 45 30 0,000 0,19186755 0,2173415 ! membrane docking GO:0022406 61 30 0,000 0,19186755 0,21723922 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,19186755 0,21713704 ! regulation of innate immune response GO:0045088 51 30 0,000 0,19186755 0,21703495 ! acute-phase response GO:0006953 49 30 0,000 0,19186755 0,21693296 ! myofibril assembly GO:0030239 47 30 0,000 0,19186755 0,21683106 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,19186755 0,21672927 ! phospholipid transport GO:0015914 51 30 0,000 0,19186755 0,21662756 ! ensheathment of neurons GO:0007272 57 30 0,000 0,19186755 0,21652596 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,19186755 0,21642444 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,19186755 0,21632303 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,19186755 0,2162217 ! eye morphogenesis GO:0048592 60 30 0,000 0,19186755 0,21612048 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1975887 0,22246066 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,1975887 0,22235661 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1975887 0,22225265 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1975887 0,2221488 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,1975887 0,22204504 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1975887 0,22194137 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,1975887 0,22183781 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1975887 0,22173434 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,1975887 0,22163097 ! peptide transport GO:0015833 55 31 0,000 0,1975887 0,22152769 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,1975887 0,22142451 ! mesoderm formation GO:0001707 69 31 0,000 0,1975887 0,22132143 ! natural killer cell activation GO:0030101 45 31 0,000 0,1975887 0,22121844 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,1975887 0,22111554 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,1975887 0,22101275 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1975887 0,22091005 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,20326954 0,22715583 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,20326954 0,22705038 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,20326954 0,22694502 ! cholesterol transport GO:0030301 56 32 0,000 0,20326954 0,22683975 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,20326954 0,22673459 ! spliceosome assembly GO:0000245 67 32 0,000 0,20326954 0,22662952 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,20326954 0,22652455 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,20326954 0,22641968 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,20326954 0,22631491 ! muscle cell development GO:0055001 49 32 0,000 0,20326954 0,22621023 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,20326954 0,22610565 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,20326954 0,22600116 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,20326954 0,22589677 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,20326954 0,22579248 ! peripheral nervous system development GO:0007422 64 32 0,000 0,20326954 0,22568828 ! BMP signaling pathway GO:0030509 64 32 0,000 0,20326954 0,22558418 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,20326954 0,22548018 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,20326954 0,22537627 ! gene silencing GO:0016458 65 32 0,000 0,20326954 0,22527246 ! protein targeting to membrane GO:0006612 68 33 0,000 0,20891034 0,23141726 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,20891034 0,23131076 ! ceramide metabolic process GO:0006672 64 33 0,000 0,20891034 0,23120436 ! formation of primary germ layer GO:0001704 72 33 0,000 0,20891034 0,23109806 ! cell fate specification GO:0001708 52 33 0,000 0,20891034 0,23099186 ! sterol transport GO:0015918 57 33 0,000 0,20891034 0,23088575 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,20891034 0,23077975 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,20891034 0,23067383 ! adult locomotory behavior GO:0008344 59 33 0,000 0,20891034 0,23056802 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,20891034 0,2304623 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,2145114 0,23653273 ! glial cell differentiation GO:0010001 63 34 0,000 0,2145114 0,23642438 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,2145114 0,23631613 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,2145114 0,23620797 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,2145114 0,23609992 ! mismatch repair GO:0006298 46 34 0,000 0,2145114 0,23599196 ! spermatid development GO:0007286 63 34 0,000 0,2145114 0,2358841 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,2145114 0,23577635 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,2145114 0,23566869 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,22007298 0,24166846 ! negative regulation of secretion GO:0051048 63 35 0,000 0,22007298 0,24155821 ! odontogenesis GO:0042476 66 35 0,000 0,22007298 0,24144806 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,22007298 0,24133801 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,22007298 0,24122806 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,22007298 0,24111821 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,22007298 0,24100846 ! cytokine production GO:0001816 59 35 0,000 0,22007298 0,24089881 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,22007298 0,24078926 ! vesicle localization GO:0051648 64 35 0,000 0,22007298 0,24067981 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,22559537 0,2466072 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,22559537 0,24649521 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,22559537 0,24638332 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,22559537 0,24627153 ! aerobic respiration GO:0009060 55 36 0,000 0,22559537 0,24615984 ! embryonic organ development GO:0048568 57 36 0,000 0,22559537 0,24604826 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,22559537 0,24593677 ! RNA export from nucleus GO:0006405 56 37 0,000 0,23107883 0,25180058 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,23107883 0,25168659 ! actomyosin structure organization GO:0031032 62 37 0,000 0,23107883 0,2515727 ! organic anion transport GO:0015711 68 37 0,000 0,23107883 0,25145892 ! tissue remodeling GO:0048771 76 37 0,000 0,23107883 0,25134524 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,23107883 0,25123166 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,23107883 0,25111819 ! spermatid differentiation GO:0048515 66 37 0,000 0,23107883 0,25100482 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,23652365 0,25680321 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,23652365 0,25668738 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,23652365 0,25657165 ! lipid homeostasis GO:0055088 67 38 0,000 0,23652365 0,25645602 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,23652365 0,2563405 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,23652365 0,25622508 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,23652365 0,25610977 ! mRNA catabolic process GO:0006402 71 39 0,000 0,2419301 0,26184607 ! organic ether metabolic process GO:0018904 55 39 0,000 0,2419301 0,26172834 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,2419301 0,26161071 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,2419301 0,26149318 ! RNA modification GO:0009451 57 39 0,000 0,2419301 0,26137576 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,2419301 0,26125845 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,24729844 0,26693586 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,24729844 0,26681616 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,24729844 0,26669657 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,24729844 0,26657708 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,24729844 0,2664577 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,25262894 0,27207933 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,25262894 0,27195759 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,25262894 0,27183597 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,25262894 0,27171445 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,25262894 0,27159304 ! polyol metabolic process GO:0019751 66 41 0,000 0,25262894 0,27147174 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,25262894 0,27135055 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,25792186 0,27691209 ! regulation of tube size GO:0035150 71 42 0,000 0,25792186 0,27678858 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,25792186 0,27666518 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,25792186 0,27654189 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,25792186 0,27641871 ! regulation of protein secretion GO:0050708 71 42 0,000 0,25792186 0,27629564 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,26317748 0,28180018 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,26317748 0,28167483 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,26317748 0,28154958 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,26317748 0,28142445 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,26317748 0,28129943 ! striated muscle contraction GO:0006941 77 43 0,000 0,26317748 0,28117452 ! phagocytosis GO:0006909 90 43 0,000 0,26317748 0,28104972 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,26317748 0,28092503 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,26839605 0,28636846 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,26839605 0,28624153 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,27357783 0,29163857 ! glycolysis GO:0006096 65 45 0,000 0,27357783 0,29150941 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,27357783 0,29138037 ! leukocyte migration GO:0050900 68 45 0,000 0,27357783 0,29125144 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,27357783 0,29112262 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,27357783 0,29099392 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,27357783 0,29086533 ! cell growth GO:0016049 84 45 0,000 0,27357783 0,29073686 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,27872307 0,29607405 ! positive regulation of defense response GO:0031349 76 47 0,000 0,28383205 0,30136801 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,28383205 0,30123507 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,28383205 0,30110225 ! JNK cascade GO:0007254 91 47 0,000 0,28383205 0,30096955 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,28383205 0,30083697 ! protein homooligomerization GO:0051260 76 47 0,000 0,28383205 0,3007045 ! Notch signaling pathway GO:0007219 96 48 0,000 0,288905 0,3059443 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,288905 0,3058097 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,288905 0,30567522 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,288905 0,30554085 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,288905 0,30540661 ! regulation of action potential GO:0001508 95 49 0,000 0,29394219 0,31059505 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,29394219 0,3104587 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,29394219 0,31032247 ! regulation of ion transport GO:0043269 77 49 0,000 0,29394219 0,31018637 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,29394219 0,31005038 ! endocrine system development GO:0035270 104 49 0,000 0,29394219 0,30991451 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,29394219 0,30977876 ! neuromuscular process GO:0050905 99 50 0,000 0,29894387 0,31491197 ! inner ear development GO:0048839 79 50 0,000 0,29894387 0,31477416 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,30391027 0,31986357 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,30391027 0,31972371 ! excretion GO:0007588 83 51 0,000 0,30391027 0,31958397 ! chromatin remodeling GO:0006338 109 51 0,000 0,30391027 0,31944435 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,30391027 0,31930486 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,30884166 0,32434441 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,30884166 0,3242029 ! cartilage development GO:0051216 90 52 0,000 0,30884166 0,32406151 ! synapse organization GO:0050808 85 52 0,000 0,30884166 0,32392024 ! RNA catabolic process GO:0006401 93 53 0,000 0,31373828 0,32891255 ! regulation of translational initiation GO:0006446 82 53 0,000 0,31373828 0,32876929 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,31373828 0,32862616 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,31373828 0,32848316 ! cell maturation GO:0048469 100 53 0,000 0,31373828 0,32834028 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,31373828 0,32819752 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,31860036 0,33313884 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,31860036 0,33299412 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,31860036 0,33284953 ! cell recognition GO:0008037 85 54 0,000 0,31860036 0,33270507 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,31860036 0,33256073 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,31860036 0,33241651 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,31860036 0,33227242 ! glucose catabolic process GO:0006007 82 55 0,000 0,32342816 0,33716125 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,32342816 0,33701523 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,32342816 0,33686933 ! gastrulation GO:0007369 112 55 0,000 0,32342816 0,33672356 ! regulation of actin filament length GO:0030832 105 56 0,000 0,32822191 0,34156658 ! sensory perception of smell GO:0007608 80 56 0,000 0,32822191 0,3414189 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,32822191 0,34127136 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,32822191 0,34112394 ! muscle fiber development GO:0048747 112 57 0,000 0,33298186 0,34592157 ! lipid modification GO:0030258 97 57 0,000 0,33298186 0,34577227 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,33298186 0,3456231 ! adult behavior GO:0030534 99 58 0,000 0,33770824 0,35037776 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,33770824 0,35022673 ! positive regulation of secretion GO:0051047 95 59 0,000 0,34240128 0,35494075 ! regulation of cellular component size GO:0032535 109 59 0,000 0,34240128 0,35478789 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,34240128 0,35463516 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,34240128 0,35448256 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,34706122 0,35915239 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,34706122 0,35899798 ! regulation of heart contraction GO:0008016 110 60 0,000 0,34706122 0,3588437 ! camera-type eye development GO:0043010 116 60 0,000 0,34706122 0,35868956 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,34706122 0,35853555 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,35168829 0,36315967 ! mesoderm development GO:0007498 119 61 0,000 0,35168829 0,36300388 ! tRNA processing GO:0008033 89 61 0,000 0,35168829 0,36284821 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,35168829 0,36269269 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,35628273 0,36727346 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,36084476 0,37181691 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,36084476 0,37165774 ! cell redox homeostasis GO:0045454 102 64 0,000 0,36537461 0,37616231 ! single fertilization GO:0007338 75 64 0,000 0,36537461 0,37600141 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,3698725 0,3804674 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,3698725 0,3803048 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,3698725 0,38014235 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,37433867 0,38456825 ! extracellular matrix organization GO:0030198 133 66 0,000 0,37433867 0,38440411 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,37877332 0,38879207 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,37877332 0,38862627 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,37877332 0,38846062 ! hexose catabolic process GO:0019320 104 67 0,000 0,37877332 0,38829511 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,37877332 0,38812973 ! amino acid transport GO:0006865 125 68 0,000 0,38317669 0,39247472 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,38317669 0,39230771 ! regulation of lipase activity GO:0060191 130 68 0,000 0,38317669 0,39214084 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,38317669 0,39197412 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,387549 0,39627832 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,387549 0,39610998 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,387549 0,39594178 ! appendage morphogenesis GO:0035107 135 70 0,000 0,39189045 0,40020731 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,39620128 0,40443796 ! appendage development GO:0048736 136 71 0,000 0,39620128 0,40426644 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,39620128 0,40409507 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,40048168 0,40828768 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,40048168 0,40811475 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,40048168 0,40794197 ! regulation of blood pressure GO:0008217 125 73 0,000 0,40473189 0,41209688 ! axon guidance GO:0007411 139 73 0,000 0,40473189 0,41192256 ! fertilization GO:0009566 90 73 0,000 0,40473189 0,41174838 ! transition metal ion transport GO:0000041 126 74 0,000 0,4089521 0,41586592 ! neurotransmitter transport GO:0006836 123 74 0,000 0,4089521 0,41569022 ! exocytosis GO:0006887 133 74 0,000 0,4089521 0,41551468 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,4089521 0,41533928 ! eye development GO:0001654 143 74 0,000 0,4089521 0,41516403 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,41314254 0,41924123 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,41314254 0,41906448 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,4173034 0,42310661 ! defense response to bacterium GO:0042742 89 76 0,000 0,4173034 0,42292838 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,4173034 0,42275031 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,4173034 0,42257238 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,4214349 0,42657651 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,4214349 0,42639713 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,4214349 0,42621789 ! blood coagulation GO:0007596 146 78 0,000 0,42553724 0,43018597 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,42961063 0,43412145 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,42961063 0,4339392 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,43365527 0,43784078 ! digestion GO:0007586 112 81 0,000 0,43767137 0,44171028 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,44165912 0,44554794 ! hemostasis GO:0007599 158 84 0,000 0,44955037 0,4533186 ! nucleosome assembly GO:0006334 122 85 0,000 0,45345427 0,45706366 ! amine biosynthetic process GO:0009309 138 86 0,000 0,45733061 0,46077782 ! chromatin assembly GO:0031497 124 86 0,000 0,45733061 0,46058495 ! alcohol catabolic process GO:0046164 130 86 0,000 0,45733061 0,46039223 ! amine transport GO:0015837 155 86 0,000 0,45733061 0,46019968 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,46117958 0,46387879 ! cellular defense response GO:0006968 114 89 0,000 0,46879621 0,47134295 ! ossification GO:0001503 188 90 0,000 0,47256424 0,47493298 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,47256424 0,47473468 ! bone development GO:0060348 189 91 0,000 0,47630566 0,47829358 ! sterol metabolic process GO:0016125 152 91 0,000 0,47630566 0,47809404 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,47630566 0,47789467 ! regulation of defense response GO:0031347 149 92 0,000 0,48002067 0,48142132 ! nucleosome organization GO:0034728 138 92 0,000 0,48002067 0,48122072 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,48002067 0,4810203 ! vitamin metabolic process GO:0006766 139 92 0,000 0,48002067 0,48082004 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,48370945 0,48431333 GO:0010498|proteasomal protein catabolic process, ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,48737218 0,48777765 ! hormone metabolic process GO:0042445 157 97 0,000 0,49820593 0,49841308 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,50176629 0,50176629 GO:0016054|organic acid catabolic process,