pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/427-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein sumoylation GO:0016925 15 10 5,000 2,541E-13 6,115E-10 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 9,543E-11 1,148E-07 ! myoblast cell fate commitment GO:0048625 16 6 3,000 1,778E-09 1,426E-06 ! steroid hormone receptor signaling pathway GO:0030518 129 63 5,000 7,124E-08 4,285E-05 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 5,000 1,132E-07 5,448E-05 ! positive regulation of protein complex assembly GO:0031334 32 17 3,000 2,742E-07 1,099E-04 ! myoblast differentiation GO:0045445 45 17 3,000 2,742E-07 9,424E-05 ! Notch receptor processing GO:0007220 8 5 2,000 3,643E-07 1,096E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 3,643E-07 9,739E-05 ! amyloid precursor protein catabolic process GO:0042987 11 7 2,000 1,269E-06 3,053E-04 ! skeletal muscle fiber development GO:0048741 111 56 4,000 1,28E-06 2,8E-04 ! muscle fiber development GO:0048747 112 57 4,000 1,399E-06 2,806E-04 ! fat cell differentiation GO:0045444 50 27 3,000 1,97E-06 3,647E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 2,025E-06 3,48E-04 ! amyloid precursor protein metabolic process GO:0042982 14 9 2,000 3,03E-06 4,861E-04 ! negative regulation of transcription regulator activity GO:0090048 58 31 3,000 3,496E-06 5,258E-04 GO:0043433|negative regulation of transcription factor activity, ! cell cycle checkpoint GO:0000075 137 69 4,000 3,638E-06 5,15E-04 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 5,923E-06 7,917E-04 ! androgen receptor signaling pathway GO:0030521 74 36 3,000 6,462E-06 8,183E-04 ! negative regulation of DNA binding GO:0043392 68 37 3,000 7,227E-06 8,694E-04 ! membrane protein proteolysis GO:0033619 25 12 2,000 7,878E-06 9,026E-04 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of hormone metabolic process GO:0032350 26 12 2,000 7,878E-06 8,616E-04 ! negative regulation of binding GO:0051100 72 40 3,000 9,923E-06 1,038E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 1,022E-05 1,024E-03 GO:0000725|recombinational repair, ! glycoprotein catabolic process GO:0006516 26 15 2,000 1,618E-05 1,557E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,618E-05 1,497E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 1,937E-05 1,726E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 2,139E-05 1,838E-03 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 4,000 2,245E-05 1,863E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 3,411E-05 2,736E-03 ! estrogen receptor signaling pathway GO:0030520 38 19 2,000 3,411E-05 2,648E-03 ! pancreas development GO:0031016 35 20 2,000 4,004E-05 3,01E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 4,105E-05 2,993E-03 ! regulation of protein complex assembly GO:0043254 117 61 3,000 5,368E-05 3,799E-03 ! chromosome segregation GO:0007059 113 67 3,000 7,764E-05 5,337E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 7,98E-05 5,333E-03 ! lymph vessel development GO:0001945 10 5 1,000 1,106E-04 7,194E-03 ! anagen GO:0042640 6 5 1,000 1,106E-04 7,004E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,106E-04 6,825E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,106E-04 6,654E-03 ! mitotic recombination GO:0006312 9 5 1,000 1,106E-04 6,492E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 1,106E-04 6,337E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 1,106E-04 6,19E-03 GO:0051930|regulation of sensory perception of pain, ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,145E-04 6,26E-03 GO:0090046|regulation of transcription regulator activity, ! cellular iron ion homeostasis GO:0006879 51 29 2,000 1,255E-04 6,712E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 1,255E-04 6,566E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 1,537E-04 7,867E-03 ! muscle cell differentiation GO:0042692 159 80 3,000 1,55E-04 7,767E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 1,656E-04 8,13E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,656E-04 7,967E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! hair follicle maturation GO:0048820 7 6 1,000 1,656E-04 7,811E-03 ! regulation of DNA binding GO:0051101 155 88 3,000 2,238E-04 0,01035649 ! positive regulation of protein ubiquitination GO:0031398 12 7 1,000 2,313E-04 0,01050001 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,313E-04 0,01030556 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,836E-04 0,01240441 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 2,836E-04 0,0121829 ! carbohydrate homeostasis GO:0033500 53 38 2,000 2,836E-04 0,01196917 GO:0042593|glucose homeostasis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,077E-04 0,01276511 ! prostaglandin biosynthetic process GO:0001516 14 8 1,000 3,077E-04 0,01254875 GO:0046457|prostanoid biosynthetic process, ! osteoblast development GO:0002076 16 8 1,000 3,077E-04 0,01233961 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 3,077E-04 0,01213732 ! mast cell activation GO:0045576 14 8 1,000 3,077E-04 0,01194155 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 3,077E-04 0,01175201 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 3,077E-04 0,01156838 ! regulation of protein localization GO:0032880 176 97 3,000 3,25E-04 0,01203002 ! regulation of hormone secretion GO:0046883 62 40 2,000 3,305E-04 0,01204767 ! mesenchymal cell development GO:0014031 87 40 2,000 3,305E-04 0,01186786 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! middle ear morphogenesis GO:0042474 14 9 1,000 3,948E-04 0,01396808 ! motor axon guidance GO:0008045 16 9 1,000 3,948E-04 0,01376564 ! postreplication repair GO:0006301 22 9 1,000 3,948E-04 0,01356899 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 3,948E-04 0,01337788 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 3,948E-04 0,01319207 ! regulation of telomere maintenance GO:0032204 14 9 1,000 3,948E-04 0,01301136 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 4,098E-04 0,01332422 ! double-strand break repair GO:0006302 81 44 2,000 4,387E-04 0,01407426 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 4,689E-04 0,01484504 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 4,924E-04 0,01538557 ! COPI coating of Golgi vesicle GO:0048205 19 10 1,000 4,924E-04 0,01518832 GO:0048200|Golgi transport vesicle coating, ! apical protein localization GO:0045176 15 10 1,000 4,924E-04 0,01499607 ! pigmentation GO:0043473 100 46 2,000 5,004E-04 0,01505009 ! Notch signaling pathway GO:0007219 96 48 2,000 5,674E-04 0,01685421 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 1,000 6,005E-04 0,01761935 ! Golgi vesicle budding GO:0048194 22 11 1,000 6,005E-04 0,01740707 ! detection of mechanical stimulus GO:0050982 22 11 1,000 6,005E-04 0,01719984 ! sequestering of metal ion GO:0051238 14 11 1,000 6,005E-04 0,01699749 ! regulation of embryonic development GO:0045995 27 11 1,000 6,005E-04 0,01679984 ! regulation of action potential GO:0001508 95 49 2,000 6,029E-04 0,01667469 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 6,029E-04 0,0164852 ! regulation of cell shape GO:0008360 125 51 2,000 6,782E-04 0,01833493 ! focal adhesion formation GO:0048041 35 12 1,000 7,19E-04 0,0192217 ! asymmetric protein localization GO:0008105 20 12 1,000 7,19E-04 0,01901047 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 7,19E-04 0,01880383 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 8,479E-04 0,0219357 ! regulation of DNA repair GO:0006282 21 13 1,000 8,479E-04 0,02170234 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 8,479E-04 0,0214739 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 1,000 9,87E-04 0,02473773 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 9,87E-04 0,0244827 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 9,87E-04 0,02423287 ! positive regulation of secretion GO:0051047 95 59 2,000 1,038E-03 0,02523616 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 1,09E-03 0,02623505 ! copper ion transport GO:0006825 20 15 1,000 1,136E-03 0,0270712 ! pituitary gland development GO:0021983 29 15 1,000 1,136E-03 0,0268058 ! vesicle coating GO:0006901 33 15 1,000 1,136E-03 0,02654555 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,136E-03 0,0262903 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,199E-03 0,02748075 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 1,296E-03 0,02941476 ! startle response GO:0001964 28 16 1,000 1,296E-03 0,02913985 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 1,296E-03 0,02887004 ! DNA replication initiation GO:0006270 27 16 1,000 1,296E-03 0,02860518 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,296E-03 0,02834513 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,465E-03 0,03176555 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,465E-03 0,03148193 ! regulation of striated muscle contraction GO:0006942 21 17 1,000 1,465E-03 0,03120333 ! membrane budding GO:0006900 37 17 1,000 1,465E-03 0,03092961 ! DNA unwinding during replication GO:0006268 27 17 1,000 1,465E-03 0,03066066 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,465E-03 0,03039634 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 1,566E-03 0,03220876 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 1,645E-03 0,0335429 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 1,645E-03 0,03326102 ! patterning of blood vessels GO:0001569 39 18 1,000 1,645E-03 0,03298385 ! centrosome cycle GO:0007098 25 18 1,000 1,645E-03 0,03271126 ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,645E-03 0,03244313 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,835E-03 0,03588667 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,835E-03 0,03559726 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 1,835E-03 0,03531248 ! neuromuscular junction development GO:0007528 34 19 1,000 1,835E-03 0,03503222 ! prostaglandin metabolic process GO:0006693 37 19 1,000 1,835E-03 0,03475638 GO:0006692|prostanoid metabolic process, ! cellular pigmentation GO:0033059 36 19 1,000 1,835E-03 0,03448485 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 1,835E-03 0,03421752 ! response to alkaloid GO:0043279 38 20 1,000 2,034E-03 0,03764468 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,034E-03 0,03735732 ! DNA duplex unwinding GO:0032508 31 20 1,000 2,034E-03 0,03707431 GO:0032392|DNA geometric change, ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 2,034E-03 0,03679555 ! diencephalon development GO:0021536 34 20 1,000 2,034E-03 0,03652096 ! negative regulation of T cell activation GO:0050868 40 20 1,000 2,034E-03 0,03625043 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 2,243E-03 0,03968489 ! hindlimb morphogenesis GO:0035137 43 21 1,000 2,243E-03 0,03939522 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 2,243E-03 0,03910975 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 2,243E-03 0,03882838 ! collagen catabolic process GO:0030574 28 21 1,000 2,243E-03 0,03855104 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,462E-03 0,04201355 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,462E-03 0,04171768 ! apoptotic nuclear changes GO:0030262 32 22 1,000 2,462E-03 0,04142595 ! response to metal ion GO:0010038 140 80 2,000 2,494E-03 0,04167466 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,691E-03 0,0446479 ! regulation of DNA recombination GO:0000018 48 23 1,000 2,691E-03 0,04434209 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 2,691E-03 0,04404044 ! vesicle targeting GO:0006903 43 23 1,000 2,691E-03 0,04374287 ! platelet activation GO:0030168 37 23 1,000 2,691E-03 0,0434493 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 2,929E-03 0,04698059 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,929E-03 0,04666946 ! response to inorganic substance GO:0010035 153 86 2,000 3,062E-03 0,04847074 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 3,177E-03 0,04995546 ! myelination GO:0042552 45 25 1,000 3,177E-03 0,04963107 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 3,177E-03 0,04931087 ! osteoblast differentiation GO:0001649 60 25 1,000 3,177E-03 0,04899477 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,177E-03 0,04868271 ! cellular response to nutrient levels GO:0031669 41 25 1,000 3,177E-03 0,04837459 ! positive regulation of protein modification process GO:0031401 136 88 2,000 3,268E-03 0,04944613 ! gland development GO:0048732 206 88 2,000 3,268E-03 0,04913709 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 3,373E-03 0,05041346 ! regulation of cell adhesion GO:0030155 212 89 2,000 3,373E-03 0,05010227 ! molting cycle process GO:0022404 50 26 1,000 3,434E-03 0,05068758 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! microtubule organizing center organization GO:0031023 39 26 1,000 3,434E-03 0,05037851 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 1,000 3,434E-03 0,05007318 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,434E-03 0,04977154 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 3,434E-03 0,0494735 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 3,434E-03 0,04917902 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 3,701E-03 0,05268404 ! regulation of chromosome organization GO:0033044 42 27 1,000 3,701E-03 0,05237414 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,701E-03 0,05206786 ! regulation of membrane potential GO:0042391 164 93 2,000 3,818E-03 0,05340373 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,977E-03 0,05530413 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 4,053E-03 0,05603736 ! icosanoid biosynthetic process GO:0046456 54 29 1,000 4,262E-03 0,05859401 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 4,262E-03 0,05826109 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 4,262E-03 0,05793193 ! interphase GO:0051325 213 98 2,000 4,421E-03 0,0597585 ! cell junction assembly GO:0034329 78 30 1,000 4,556E-03 0,06124281 ! ensheathment of neurons GO:0007272 57 30 1,000 4,556E-03 0,06090257 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 4,556E-03 0,06056609 ! collagen metabolic process GO:0032963 45 31 1,000 4,86E-03 0,06424722 ! myeloid leukocyte activation GO:0002274 49 31 1,000 4,86E-03 0,06389614 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 1,000 5,173E-03 0,06763799 ! response to mechanical stimulus GO:0009612 57 32 1,000 5,173E-03 0,06727238 ! peripheral nervous system development GO:0007422 64 32 1,000 5,173E-03 0,0669107 ! DNA damage checkpoint GO:0000077 71 33 1,000 5,494E-03 0,07069253 ! adult locomotory behavior GO:0008344 59 33 1,000 5,494E-03 0,07031651 ! establishment of vesicle localization GO:0051650 61 33 1,000 5,494E-03 0,06994446 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 5,825E-03 0,07376411 ! regulation of microtubule-based process GO:0032886 78 35 1,000 6,165E-03 0,07765587 ! vesicle localization GO:0051648 64 35 1,000 6,165E-03 0,07725141 ! cell junction organization GO:0034330 86 36 1,000 6,513E-03 0,08119495 ! DNA integrity checkpoint GO:0031570 75 36 1,000 6,513E-03 0,08077642 ! negative regulation of cell activation GO:0050866 65 36 1,000 6,513E-03 0,08036218 ! meiosis I GO:0007127 65 37 1,000 6,87E-03 0,08433722 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 6,87E-03 0,08390911 ! nucleus organization GO:0006997 67 38 1,000 7,236E-03 0,08793197 ! mammary gland development GO:0030879 86 39 1,000 7,611E-03 0,09201903 ! ear morphogenesis GO:0042471 60 39 1,000 7,611E-03 0,09155893 ! regulation of action potential in neuron GO:0019228 73 39 1,000 7,611E-03 0,09110342 ! Rho protein signal transduction GO:0007266 74 39 1,000 7,611E-03 0,09065241 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 7,994E-03 0,09474737 ! regulation of T cell proliferation GO:0042129 71 41 1,000 8,386E-03 0,0989028 ! T cell differentiation GO:0030217 81 41 1,000 8,386E-03 0,09842034 ! regulation of T cell differentiation GO:0045580 70 41 1,000 8,386E-03 0,09794257 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 8,786E-03 0,10212081 ! glucose transport GO:0015758 65 43 1,000 9,195E-03 0,10635616 ! hexose transport GO:0008645 67 44 1,000 9,611E-03 0,11064712 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 9,611E-03 0,11012023 ! developmental growth GO:0048589 82 44 1,000 9,611E-03 0,10959833 ! maintenance of location in cell GO:0051651 97 44 1,000 9,611E-03 0,10908136 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01003673 0,11337261 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,01003673 0,11284283 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,01003673 0,11231798 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,0104702 0,11662635 ! response to insulin stimulus GO:0032868 95 46 1,000 0,0104702 0,1160889 ! response to calcium ion GO:0051592 81 47 1,000 0,01091184 0,12043066 ! protein homooligomerization GO:0051260 76 47 1,000 0,01091184 0,11988074 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,0113616 0,12425454 ! cellular component disassembly GO:0022411 86 48 1,000 0,0113616 0,12369231 ! activation of caspase activity GO:0006919 84 48 1,000 0,0113616 0,12313513 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,0113616 0,12258296 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0113616 0,12203571 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,0113616 0,12149333 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,01181941 0,12582966 ! endocrine system development GO:0035270 104 49 1,000 0,01181941 0,12527534 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01181941 0,12472589 ! neuromuscular process GO:0050905 99 50 1,000 0,01228522 0,12907533 ! regulation of ossification GO:0030278 117 50 1,000 0,01228522 0,12851413 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01228522 0,12795779 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01228522 0,12740625 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01275898 0,13175152 ! vesicle organization GO:0016050 107 51 1,000 0,01275898 0,13118848 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01275898 0,13063023 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01324062 0,13498698 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,01324062 0,13441742 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,01324062 0,13385264 ! cartilage development GO:0051216 90 52 1,000 0,01324062 0,13329259 ! synapse organization GO:0050808 85 52 1,000 0,01324062 0,1327372 ! response to UV GO:0009411 104 53 1,000 0,01373008 0,13707296 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01422732 0,14145014 ! cell recognition GO:0008037 85 54 1,000 0,01422732 0,14086804 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01473227 0,14526984 GO:0010952|positive regulation of peptidase activity, ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01576508 0,15481956 ! maintenance of location GO:0051235 118 57 1,000 0,01576508 0,15419021 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01629284 0,15870675 ! adult behavior GO:0030534 99 58 1,000 0,01629284 0,1580668 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01665695 0,16095027 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01665695 0,16030647 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01665695 0,1596678 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01665695 0,1590342 ! neuron fate determination GO:0048664 7 5 0,000 0,01665695 0,1584056 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01665695 0,15778196 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01665695 0,15716321 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01665695 0,15654929 ! polyol transport GO:0015791 12 5 0,000 0,01665695 0,15594015 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01665695 0,15533573 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01665695 0,15473597 ! response to superoxide GO:0000303 10 5 0,000 0,01665695 0,15414084 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01665695 0,15355026 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01665695 0,15296419 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01665695 0,15238258 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01665695 0,15180537 ! female meiosis GO:0007143 7 5 0,000 0,01665695 0,15123252 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01665695 0,15066397 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01665695 0,15009969 ! cobalt ion transport GO:0006824 11 5 0,000 0,01665695 0,14953962 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01665695 0,14898371 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01665695 0,14843192 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01665695 0,1478842 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01665695 0,1473405 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01665695 0,1468008 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01665695 0,14626503 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01665695 0,14573315 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01665695 0,14520514 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01665695 0,14468093 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01665695 0,14416049 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01665695 0,14364379 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01665695 0,14313078 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01665695 0,14262141 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01665695 0,14211566 ! negative chemotaxis GO:0050919 14 5 0,000 0,01665695 0,14161349 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01665695 0,14111485 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01665695 0,14061971 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01665695 0,14012803 ! behavioral response to pain GO:0048266 9 5 0,000 0,01665695 0,13963978 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01665695 0,13915492 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01665695 0,13867342 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01665695 0,13819523 ! micturition GO:0060073 9 5 0,000 0,01665695 0,13772033 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01665695 0,13724869 ! copulation GO:0007620 9 5 0,000 0,01665695 0,13678026 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01665695 0,13631502 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01665695 0,13585294 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01665695 0,13539398 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01665695 0,13493811 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01665695 0,13448529 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01665695 0,13403551 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01665695 0,13358872 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01665695 0,13314491 ! grooming behavior GO:0007625 6 5 0,000 0,01665695 0,13270403 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01665695 0,13226606 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01665695 0,13183098 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01665695 0,13139875 ! response to protozoan GO:0001562 10 5 0,000 0,01665695 0,13096934 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01665695 0,13054273 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01665695 0,13011889 ! endochondral ossification GO:0001958 16 5 0,000 0,01665695 0,12969779 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01665695 0,12927941 ! parathyroid gland development GO:0060017 13 5 0,000 0,01665695 0,12886372 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01665695 0,1284507 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01665695 0,12804031 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01665695 0,12763254 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01665695 0,12722736 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01665695 0,12682474 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01665695 0,12642466 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01665695 0,1260271 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01665695 0,12563203 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01665695 0,12523943 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01665695 0,12484928 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01665695 0,12446154 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01665695 0,12407621 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01665695 0,12369326 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01665695 0,12331267 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01665695 0,12293441 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01665695 0,12255846 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01665695 0,12218481 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01665695 0,12181343 ! histidine catabolic process GO:0006548 6 5 0,000 0,01665695 0,12144429 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01665695 0,12107739 ! microvillus organization GO:0032528 7 5 0,000 0,01665695 0,1207127 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01665695 0,1203502 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01665695 0,11998987 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01665695 0,11963169 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01665695 0,11927565 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01665695 0,11892171 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01665695 0,11856987 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01665695 0,11822011 ! polyol catabolic process GO:0046174 7 5 0,000 0,01665695 0,1178724 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01665695 0,11752674 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01665695 0,11718309 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01665695 0,11684145 ! muscle cell migration GO:0014812 8 5 0,000 0,01665695 0,11650179 ! mitochondrial fission GO:0000266 8 5 0,000 0,01665695 0,11616411 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01665695 0,11582837 ! mRNA transcription GO:0009299 9 5 0,000 0,01665695 0,11549457 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01665695 0,11516269 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01665695 0,11483271 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01665695 0,11450462 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01665695 0,1141784 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01665695 0,11385403 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01665695 0,11353149 ! response to food GO:0032094 6 5 0,000 0,01665695 0,11321078 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01665695 0,11289188 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01665695 0,11257477 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01665695 0,11225943 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01665695 0,11194586 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01665695 0,11163403 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01665695 0,11132394 ! forebrain neuron development GO:0021884 13 5 0,000 0,01665695 0,11101556 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01665695 0,11070889 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01665695 0,1104039 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01665695 0,1101006 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01665695 0,10979895 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01665695 0,10949895 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01665695 0,10920059 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01665695 0,10890385 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01665695 0,10860872 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01665695 0,10831518 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01665695 0,10802323 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01665695 0,10773284 ! basic amino acid transport GO:0015802 11 5 0,000 0,01665695 0,10744401 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01665695 0,10715673 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01665695 0,10687098 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01665695 0,10658675 ! depyrimidination GO:0045008 10 5 0,000 0,01665695 0,10630402 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01665695 0,1060228 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01665695 0,10574305 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01665695 0,10546478 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01665695 0,10518797 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01665695 0,10491261 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01665695 0,10463869 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01665695 0,10436619 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01665695 0,10409511 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01665695 0,10382543 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01665695 0,10355715 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01665695 0,10329025 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01665695 0,10302472 ! response to arsenic GO:0046685 10 5 0,000 0,01665695 0,10276056 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01665695 0,10249774 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01665695 0,10223627 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01665695 0,10197613 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01665695 0,1017173 ! response to cadmium ion GO:0046686 7 5 0,000 0,01665695 0,10145979 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01665695 0,10120358 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01665695 0,10094866 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01665695 0,10069502 ! decidualization GO:0046697 11 5 0,000 0,01665695 0,10044265 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01665695 0,10019154 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01665695 0,09994169 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01665695 0,09969308 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01665695 0,0994457 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01665695 0,09919955 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01665695 0,09895461 ! neural tube patterning GO:0021532 7 5 0,000 0,01665695 0,09871088 ! embryonic cleavage GO:0040016 6 5 0,000 0,01665695 0,09846835 ! peroxisome fission GO:0016559 5 5 0,000 0,01665695 0,098227 ! histone demethylation GO:0016577 10 5 0,000 0,01665695 0,09798684 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01665695 0,09774785 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01665695 0,09751002 ! metaphase plate congression GO:0051310 7 5 0,000 0,01665695 0,09727334 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01665695 0,09703781 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01665695 0,09680342 ! enteric nervous system development GO:0048484 8 5 0,000 0,01665695 0,09657016 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01665695 0,09633802 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01665695 0,096107 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01665695 0,09587707 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01665695 0,09564825 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01665695 0,09542052 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01665695 0,09519387 ! plasminogen activation GO:0031639 5 5 0,000 0,01665695 0,09496829 ! B cell homeostasis GO:0001782 13 5 0,000 0,01665695 0,09474378 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01665695 0,09452032 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01665695 0,09429792 ! metaphase GO:0051323 8 5 0,000 0,01665695 0,09407657 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01665695 0,09385625 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01665695 0,09363696 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01665695 0,09341869 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01665695 0,09320144 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01665695 0,09298519 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01665695 0,09276995 ! response to redox state GO:0051775 5 5 0,000 0,01665695 0,0925557 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01665695 0,09234244 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01665695 0,09213015 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01665695 0,09191885 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01665695 0,09170851 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01665695 0,09149913 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01665695 0,0912907 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01665695 0,09108322 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01665695 0,09087668 ! striatum development GO:0021756 9 5 0,000 0,01665695 0,09067108 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01665695 0,0904664 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01665695 0,09026265 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01665695 0,09005981 ! glial cell migration GO:0008347 11 5 0,000 0,01665695 0,08985789 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01665695 0,08965686 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01665695 0,08945674 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01665695 0,0892575 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01665695 0,08905915 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01665695 0,08886168 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01665695 0,08866508 ! neuroprotection GO:0043526 6 5 0,000 0,01665695 0,08846935 ! neural plate development GO:0001840 8 5 0,000 0,01665695 0,08827449 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01665695 0,08808048 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01665695 0,08788732 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01665695 0,08769501 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01665695 0,08750353 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01665695 0,08731289 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01665695 0,08712308 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01665695 0,08693409 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01665695 0,08674592 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01665695 0,08655857 ! spindle assembly GO:0051225 6 5 0,000 0,01665695 0,08637202 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01665695 0,08618627 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01665695 0,08600132 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01665695 0,08581717 ! drug metabolic process GO:0017144 6 5 0,000 0,01665695 0,0856338 ! stem cell division GO:0017145 11 5 0,000 0,01665695 0,08545121 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01665695 0,0852694 ! organ regeneration GO:0031100 7 5 0,000 0,01665695 0,08508836 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01665695 0,08490809 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01665695 0,08472858 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01665695 0,08454983 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,01682808 0,08523866 ! DNA catabolic process GO:0006308 86 59 1,000 0,01682808 0,08505959 ! establishment of organelle localization GO:0051656 109 59 1,000 0,01682808 0,08488126 ! regulation of heart contraction GO:0008016 110 60 1,000 0,01737076 0,08743525 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01737076 0,08725271 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,01792082 0,0898281 ! ear development GO:0043583 103 62 1,000 0,0184782 0,09242943 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,01904286 0,09505626 ! detection of external stimulus GO:0009581 91 63 1,000 0,01904286 0,09485946 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01995522 0,0991989 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01995522 0,09899436 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01995522 0,09879067 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01995522 0,09858782 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01995522 0,09838579 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01995522 0,09818459 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01995522 0,09798422 ! sleep GO:0030431 13 6 0,000 0,01995522 0,09778466 ! response to oxygen radical GO:0000305 11 6 0,000 0,01995522 0,09758591 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01995522 0,09738796 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01995522 0,09719082 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01995522 0,09699448 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01995522 0,09679892 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01995522 0,09660416 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01995522 0,09641017 ! forebrain regionalization GO:0021871 8 6 0,000 0,01995522 0,09621697 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01995522 0,09602453 ! male meiosis GO:0007140 7 6 0,000 0,01995522 0,09583287 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01995522 0,09564196 ! response to zinc ion GO:0010043 9 6 0,000 0,01995522 0,09545182 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01995522 0,09526243 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01995522 0,09507379 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01995522 0,0948859 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01995522 0,09469875 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01995522 0,09451234 ! malate metabolic process GO:0006108 11 6 0,000 0,01995522 0,09432665 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01995522 0,0941417 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01995522 0,09395747 ! protein refolding GO:0042026 15 6 0,000 0,01995522 0,09377396 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01995522 0,09359116 ! opsonization GO:0008228 8 6 0,000 0,01995522 0,09340908 ! mating behavior GO:0007617 7 6 0,000 0,01995522 0,0932277 ! neuron remodeling GO:0016322 15 6 0,000 0,01995522 0,09304703 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01995522 0,09286705 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01995522 0,09268777 ! equilibrioception GO:0050957 14 6 0,000 0,01995522 0,09250918 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01995522 0,09233128 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01995522 0,09215406 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01995522 0,09197752 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01995522 0,09180166 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01995522 0,09162646 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01995522 0,09145194 ! toxin metabolic process GO:0009404 11 6 0,000 0,01995522 0,09127807 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01995522 0,09110487 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01995522 0,09093232 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01995522 0,09076043 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01995522 0,09058918 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01995522 0,09041858 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01995522 0,09024862 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01995522 0,0900793 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01995522 0,08991061 ! thymic T cell selection GO:0045061 12 6 0,000 0,01995522 0,08974255 ! protein lipoylation GO:0009249 10 6 0,000 0,01995522 0,08957512 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01995522 0,08940832 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01995522 0,08924213 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01995522 0,08907656 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01995522 0,0889116 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01995522 0,08874726 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01995522 0,08858352 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01995522 0,08842038 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01995522 0,08825784 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01995522 0,0880959 ! hyperosmotic response GO:0006972 9 6 0,000 0,01995522 0,08793455 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01995522 0,0877738 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01995522 0,08761362 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01995522 0,08745404 ! urea metabolic process GO:0019627 7 6 0,000 0,01995522 0,08729503 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01995522 0,0871366 ! neutrophil activation GO:0042119 8 6 0,000 0,01995522 0,08697874 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01995522 0,08682146 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01995522 0,08666474 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01995522 0,08650859 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01995522 0,086353 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01995522 0,08619796 ! neuron apoptosis GO:0051402 9 6 0,000 0,01995522 0,08604349 ! nucleoside salvage GO:0043174 9 6 0,000 0,01995522 0,08588956 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01995522 0,08573619 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01995522 0,08558336 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01995522 0,08543108 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01995522 0,08527934 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01995522 0,08512813 ! carnitine transport GO:0015879 10 6 0,000 0,01995522 0,08497746 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01995522 0,08482733 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01995522 0,08467772 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01995522 0,08452864 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01995522 0,08438008 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01995522 0,08423205 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01995522 0,08408453 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01995522 0,08393753 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01995522 0,08379104 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01995522 0,08364506 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01995522 0,08349959 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01995522 0,08335463 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01995522 0,08321017 ! neural nucleus development GO:0048857 14 6 0,000 0,01995522 0,0830662 ! response to UV-C GO:0010225 11 6 0,000 0,01995522 0,08292274 ! astrocyte development GO:0014002 15 6 0,000 0,01995522 0,08277977 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01995522 0,08263729 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01995522 0,0824953 ! interaction with symbiont GO:0051702 13 6 0,000 0,01995522 0,0823538 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01995522 0,08221278 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01995522 0,08207225 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01995522 0,08193219 ! response to copper ion GO:0046688 10 6 0,000 0,01995522 0,08179262 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01995522 0,08165351 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01995522 0,08151488 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01995522 0,08137672 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01995522 0,08123903 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01995522 0,0811018 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01995522 0,08096504 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01995522 0,08082873 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01995522 0,08069288 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01995522 0,08055749 ! Schwann cell development GO:0014044 15 6 0,000 0,01995522 0,08042256 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01995522 0,08028807 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01995522 0,08015403 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01995522 0,08002044 ! subpallium development GO:0021544 10 6 0,000 0,01995522 0,0798873 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01995522 0,0797546 ! histone ubiquitination GO:0016574 8 6 0,000 0,01995522 0,07962233 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01995522 0,07949051 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01995522 0,07935912 ! G2 phase GO:0051319 16 6 0,000 0,01995522 0,07922816 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01995522 0,07909764 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01995522 0,07896754 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01995522 0,07883788 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01995522 0,07870863 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01995522 0,07857981 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01995522 0,07845142 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01995522 0,07832344 ! receptor internalization GO:0031623 10 6 0,000 0,01995522 0,07819587 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01995522 0,07806873 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01995522 0,07794199 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01995522 0,07781567 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01995522 0,07768975 ! protein deubiquitination GO:0016579 14 6 0,000 0,01995522 0,07756424 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01995522 0,07743914 ! protein destabilization GO:0031648 9 6 0,000 0,01995522 0,07731444 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01995522 0,07719014 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01995522 0,07706624 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01995522 0,07694273 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01995522 0,07681963 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01995522 0,07669691 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01995522 0,07657459 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01995522 0,07645265 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01995522 0,07633111 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01995522 0,07620995 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01995522 0,07608917 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01995522 0,07596878 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01995522 0,07584876 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01995522 0,07572913 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01995522 0,07560987 ! catecholamine transport GO:0051937 9 6 0,000 0,01995522 0,07549098 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01995522 0,07537247 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01995522 0,07525434 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01995522 0,07513657 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01995522 0,07501917 ! maternal placenta development GO:0001893 12 6 0,000 0,01995522 0,07490213 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01995522 0,07478546 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01995522 0,07466915 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01995522 0,07455321 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01995522 0,07443762 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01995522 0,07432239 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01995522 0,07420752 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01995522 0,074093 ! actin filament organization GO:0007015 148 66 1,000 0,02077992 0,07703617 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,02077992 0,07691766 ! developmental maturation GO:0021700 116 66 1,000 0,02077992 0,0767995 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,02137312 0,07887074 ! appendage morphogenesis GO:0035107 135 70 1,000 0,02319454 0,08546106 GO:0035108|limb morphogenesis, ! tRNA transcription GO:0009304 14 7 0,000 0,02324254 0,08550697 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02324254 0,08537643 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02324254 0,08524628 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02324254 0,08511653 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02324254 0,08498717 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02324254 0,08485821 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02324254 0,08472964 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02324254 0,08460145 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02324254 0,08447366 ! prostate gland development GO:0030850 13 7 0,000 0,02324254 0,08434625 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02324254 0,08421922 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02324254 0,08409257 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02324254 0,08396631 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02324254 0,08384042 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02324254 0,08371491 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02324254 0,08358978 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02324254 0,08346502 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02324254 0,08334063 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02324254 0,08321661 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02324254 0,08309296 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02324254 0,08296967 ! glycolipid transport GO:0046836 10 7 0,000 0,02324254 0,08284676 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02324254 0,0827242 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02324254 0,08260201 ! neuron adhesion GO:0007158 12 7 0,000 0,02324254 0,08248018 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02324254 0,0823587 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02324254 0,08223759 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02324254 0,08211683 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02324254 0,08199642 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02324254 0,08187637 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02324254 0,08175667 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02324254 0,08163731 ! mRNA stabilization GO:0048255 18 7 0,000 0,02324254 0,08151831 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02324254 0,08139965 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02324254 0,08128134 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02324254 0,08116337 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02324254 0,08104574 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02324254 0,08092845 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02324254 0,0808115 ! lipoprotein transport GO:0042953 14 7 0,000 0,02324254 0,08069489 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02324254 0,08057862 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02324254 0,08046268 ! rhythmic behavior GO:0007622 15 7 0,000 0,02324254 0,08034707 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02324254 0,08023179 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02324254 0,08011685 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02324254 0,08000223 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02324254 0,07988794 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02324254 0,07977398 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02324254 0,07966034 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02324254 0,07954703 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02324254 0,07943403 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02324254 0,07932136 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02324254 0,07920901 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02324254 0,07909697 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02324254 0,07898526 ! spinal cord patterning GO:0021511 13 7 0,000 0,02324254 0,07887385 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02324254 0,07876276 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02324254 0,07865198 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02324254 0,07854152 ! adrenal gland development GO:0030325 17 7 0,000 0,02324254 0,07843136 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02324254 0,07832151 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02324254 0,07821197 ! ovulation GO:0030728 9 7 0,000 0,02324254 0,07810274 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02324254 0,07799381 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02324254 0,07788518 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02324254 0,07777686 ! microtubule nucleation GO:0007020 20 7 0,000 0,02324254 0,07766883 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02324254 0,07756111 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02324254 0,07745369 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02324254 0,07734656 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02324254 0,07723972 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02324254 0,07713319 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02324254 0,07702694 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02324254 0,07692099 ! galactose metabolic process GO:0006012 13 7 0,000 0,02324254 0,07681533 ! vesicle fusion GO:0006906 17 7 0,000 0,02324254 0,07670996 ! response to dietary excess GO:0002021 8 7 0,000 0,02324254 0,07660488 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02324254 0,07650008 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02324254 0,07639557 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02324254 0,07629135 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02324254 0,07618741 ! organ growth GO:0035265 15 7 0,000 0,02324254 0,07608376 ! purine salvage GO:0043101 10 7 0,000 0,02324254 0,07598038 ! nucleoside transport GO:0015858 8 7 0,000 0,02324254 0,07587729 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02324254 0,07577447 ! parturition GO:0007567 14 7 0,000 0,02324254 0,07567194 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02324254 0,07556968 ! rRNA modification GO:0000154 14 7 0,000 0,02324254 0,07546769 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02324254 0,07536598 ! spindle checkpoint GO:0031577 15 7 0,000 0,02324254 0,07526455 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02324254 0,07516339 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02324254 0,0750625 ! macrophage differentiation GO:0030225 11 7 0,000 0,02324254 0,07496188 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02324254 0,07486153 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02324254 0,07476144 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02324254 0,07466163 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02324254 0,07456208 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02324254 0,0744628 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02324254 0,07436378 ! fibrinolysis GO:0042730 10 7 0,000 0,02324254 0,07426502 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02324254 0,07416653 ! eating behavior GO:0042755 7 7 0,000 0,02324254 0,07406829 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02324254 0,07397032 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02324254 0,0738726 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02324254 0,07377515 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02324254 0,07367795 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02324254 0,073581 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02324254 0,07348431 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02324254 0,07338787 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02324254 0,07329169 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02324254 0,07319576 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02324254 0,07310008 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02324254 0,07300465 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02324254 0,07290947 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02324254 0,07281453 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02324254 0,07271984 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02324254 0,0726254 ! regulation of meiosis GO:0040020 12 7 0,000 0,02324254 0,07253121 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02324254 0,07243725 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02324254 0,07234355 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02324254 0,07225008 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02324254 0,07215685 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02324254 0,07206387 ! transcription termination GO:0006353 13 7 0,000 0,02324254 0,07197112 ! response to tumor cell GO:0002347 13 7 0,000 0,02324254 0,07187861 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02324254 0,07178634 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02324254 0,07169431 ! anaphase GO:0051322 17 7 0,000 0,02324254 0,07160251 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02324254 0,07151095 ! axonal fasciculation GO:0007413 18 7 0,000 0,02324254 0,07141962 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02324254 0,07132852 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02324254 0,07123766 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02324254 0,07114702 ! diuresis GO:0030146 12 7 0,000 0,02324254 0,07105662 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02324254 0,07096645 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02324254 0,0708765 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02324254 0,07078679 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02324254 0,0706973 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02324254 0,07060803 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02324254 0,07051899 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02324254 0,07043018 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02324254 0,07034159 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02324254 0,07025322 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02324254 0,07016507 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02324254 0,07007714 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02324254 0,06998944 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02324254 0,06990195 ! lymph node development GO:0048535 10 7 0,000 0,02324254 0,06981468 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02324254 0,06972763 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02324254 0,0696408 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02324254 0,06955418 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02324254 0,06946778 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02324254 0,06938159 ! adult feeding behavior GO:0008343 9 7 0,000 0,02324254 0,06929561 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02324254 0,06920985 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02324254 0,0691243 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02324254 0,06903896 ! muscle adaptation GO:0043500 14 7 0,000 0,02324254 0,06895384 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02324254 0,06886892 ! retina homeostasis GO:0001895 12 7 0,000 0,02324254 0,06878421 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02324254 0,06869971 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02324254 0,06861541 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02324254 0,06853132 ! protein prenylation GO:0018342 18 7 0,000 0,02324254 0,06844744 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02324254 0,06836377 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02324254 0,06828029 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02324254 0,06819703 ! appendage development GO:0048736 136 71 1,000 0,02381545 0,0697929 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 1,000 0,02444315 0,07154528 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,02444315 0,07145834 ! carbohydrate transport GO:0008643 110 72 1,000 0,02444315 0,07137162 ! learning or memory GO:0007611 147 73 1,000 0,02507759 0,07313538 ! regulation of blood pressure GO:0008217 125 73 1,000 0,02507759 0,07304684 ! axon guidance GO:0007411 139 73 1,000 0,02507759 0,07295851 ! transition metal ion transport GO:0000041 126 74 1,000 0,02571873 0,07473341 ! meiosis GO:0007126 121 74 1,000 0,02571873 0,07464326 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02571873 0,07455333 ! organelle localization GO:0051640 136 74 1,000 0,02571873 0,07446361 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,0263665 0,07624737 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,0263665 0,07615584 ! meiotic cell cycle GO:0051321 122 75 1,000 0,0263665 0,07606452 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,0263665 0,07597343 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02651895 0,07632128 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02651895 0,07623009 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02651895 0,07613913 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02651895 0,07604838 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02651895 0,07595784 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02651895 0,07586752 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02651895 0,07577742 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02651895 0,07568753 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02651895 0,07559785 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02651895 0,07550839 ! meiotic prophase I GO:0007128 13 8 0,000 0,02651895 0,07541913 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02651895 0,07533009 ! oligopeptide transport GO:0006857 15 8 0,000 0,02651895 0,07524126 ! UTP metabolic process GO:0046051 8 8 0,000 0,02651895 0,07515263 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02651895 0,07506422 ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02651895 0,07497601 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02651895 0,07488801 ! succinate metabolic process GO:0006105 14 8 0,000 0,02651895 0,07480022 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02651895 0,07471263 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02651895 0,07462525 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02651895 0,07453807 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02651895 0,07445109 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02651895 0,07436432 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02651895 0,07427775 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02651895 0,07419138 ! reflex GO:0060004 16 8 0,000 0,02651895 0,07410521 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02651895 0,07401924 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02651895 0,07393347 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02651895 0,0738479 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02651895 0,07376253 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02651895 0,07367735 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02651895 0,07359237 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02651895 0,07350759 ! pigment granule organization GO:0048753 16 8 0,000 0,02651895 0,073423 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02651895 0,07333861 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02651895 0,07325441 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02651895 0,0731704 ! histidine metabolic process GO:0006547 16 8 0,000 0,02651895 0,07308658 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02651895 0,07300296 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02651895 0,07291953 ! glycine catabolic process GO:0006546 13 8 0,000 0,02651895 0,07283629 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02651895 0,07275323 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02651895 0,07267037 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02651895 0,0725877 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02651895 0,07250521 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02651895 0,07242291 ! melanin metabolic process GO:0006582 15 8 0,000 0,02651895 0,0723408 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02651895 0,07225888 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02651895 0,07217713 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02651895 0,07209558 ! macrophage activation GO:0042116 12 8 0,000 0,02651895 0,07201421 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02651895 0,07193302 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02651895 0,07185201 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02651895 0,07177119 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02651895 0,07169055 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02651895 0,07161009 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02651895 0,07152981 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02651895 0,07144971 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02651895 0,07136978 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02651895 0,07129004 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02651895 0,07121048 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02651895 0,07113109 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02651895 0,07105188 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02651895 0,07097284 ! response to UV-B GO:0010224 16 8 0,000 0,02651895 0,07089399 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02651895 0,0708153 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02651895 0,07073679 ! intermediate filament organization GO:0045109 12 8 0,000 0,02651895 0,07065846 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02651895 0,0705803 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02651895 0,07050231 ! cellular extravasation GO:0045123 12 8 0,000 0,02651895 0,07042449 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02651895 0,07034684 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02651895 0,07026937 ! response to antibiotic GO:0046677 11 8 0,000 0,02651895 0,07019206 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02651895 0,07011493 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02651895 0,07003797 ! DNA topological change GO:0006265 12 8 0,000 0,02651895 0,06996117 ! response to tropane GO:0014073 15 8 0,000 0,02651895 0,06988454 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02651895 0,06980808 ! melanosome transport GO:0032402 13 8 0,000 0,02651895 0,06973179 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02651895 0,06965566 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02651895 0,0695797 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02651895 0,06950391 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02651895 0,06942828 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02651895 0,06935281 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02651895 0,06927751 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02651895 0,06920237 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02651895 0,0691274 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02651895 0,06905258 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02651895 0,06897793 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02651895 0,06890344 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02651895 0,06882911 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02651895 0,06875494 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02651895 0,06868093 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02651895 0,06860708 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02651895 0,06853339 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02651895 0,06845986 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02651895 0,06838648 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02651895 0,06831326 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02651895 0,0682402 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02651895 0,06816729 ! hormone catabolic process GO:0042447 17 8 0,000 0,02651895 0,06809454 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02651895 0,06802195 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02651895 0,06794951 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02651895 0,06787722 ! ATP catabolic process GO:0006200 11 8 0,000 0,02651895 0,06780509 ! blastocyst growth GO:0001832 19 8 0,000 0,02651895 0,06773311 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02651895 0,06766128 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02651895 0,0675896 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02651895 0,06751808 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02651895 0,06744671 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02651895 0,06737549 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02651895 0,06730442 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02651895 0,0672335 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02651895 0,06716272 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02651895 0,0670921 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02651895 0,06702162 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02651895 0,0669513 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02651895 0,06688112 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02651895 0,06681109 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02651895 0,0667412 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02651895 0,06667146 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02651895 0,06660187 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02651895 0,06653242 ! blood coagulation GO:0007596 146 78 1,000 0,02834917 0,07105012 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02834917 0,07097618 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,02834917 0,0709024 ! protein oligomerization GO:0051259 139 78 1,000 0,02834917 0,07082878 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02902301 0,07243709 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02902301 0,07236203 ! protein import into nucleus GO:0006606 158 80 1,000 0,02970323 0,07398135 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02978447 0,07410696 ! axon extension GO:0048675 15 9 0,000 0,02978447 0,0740304 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02978447 0,07395401 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02978447 0,07387776 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02978447 0,07380168 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02978447 0,07372575 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02978447 0,07364998 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02978447 0,07357437 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02978447 0,0734989 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02978447 0,0734236 ! phosphate transport GO:0006817 19 9 0,000 0,02978447 0,07334845 ! reproductive behavior GO:0019098 19 9 0,000 0,02978447 0,07327345 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02978447 0,0731986 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02978447 0,07312391 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02978447 0,07304937 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02978447 0,07297498 ! GTP metabolic process GO:0046039 9 9 0,000 0,02978447 0,07290074 ! RNA methylation GO:0001510 15 9 0,000 0,02978447 0,07282666 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02978447 0,07275272 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02978447 0,07267894 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02978447 0,0726053 ! artery development GO:0060840 24 9 0,000 0,02978447 0,07253181 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02978447 0,07245847 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02978447 0,07238528 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02978447 0,07231224 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02978447 0,07223935 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02978447 0,0721666 ! chemosensory behavior GO:0007635 20 9 0,000 0,02978447 0,072094 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02978447 0,07202154 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02978447 0,07194923 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02978447 0,07187706 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02978447 0,07180504 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02978447 0,07173316 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02978447 0,07166143 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02978447 0,07158984 ! protein targeting to ER GO:0045047 22 9 0,000 0,02978447 0,07151839 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02978447 0,07144709 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02978447 0,07137593 ! T cell selection GO:0045058 23 9 0,000 0,02978447 0,07130491 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02978447 0,07123403 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02978447 0,07116329 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02978447 0,07109269 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02978447 0,07102223 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02978447 0,07095191 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02978447 0,07088173 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02978447 0,07081169 ! mannose metabolic process GO:0006013 13 9 0,000 0,02978447 0,07074179 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02978447 0,07067202 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02978447 0,0706024 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02978447 0,07053291 ! receptor clustering GO:0043113 18 9 0,000 0,02978447 0,07046355 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02978447 0,07039433 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02978447 0,07032525 ! ruffle organization GO:0031529 15 9 0,000 0,02978447 0,07025631 ! retinol metabolic process GO:0042572 18 9 0,000 0,02978447 0,07018749 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02978447 0,07011882 ! behavioral fear response GO:0001662 22 9 0,000 0,02978447 0,07005028 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02978447 0,06998187 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02978447 0,06991359 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02978447 0,06984545 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,02978447 0,06977744 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02978447 0,06970956 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02978447 0,06964182 ! segment specification GO:0007379 13 9 0,000 0,02978447 0,06957421 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02978447 0,06950672 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02978447 0,06943937 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02978447 0,06937215 ! response to amine stimulus GO:0014075 13 9 0,000 0,02978447 0,06930506 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02978447 0,0692381 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02978447 0,06917127 ! erythrocyte development GO:0048821 15 9 0,000 0,02978447 0,06910456 ! gas homeostasis GO:0033483 16 9 0,000 0,02978447 0,06903799 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02978447 0,06897154 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02978447 0,06890522 ! renal water homeostasis GO:0003091 14 9 0,000 0,02978447 0,06883903 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02978447 0,06877297 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02978447 0,06870703 ! icosanoid secretion GO:0032309 15 9 0,000 0,02978447 0,06864122 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02978447 0,06857553 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02978447 0,06850997 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02978447 0,06844454 ! regulation of cell division GO:0051302 15 9 0,000 0,02978447 0,06837923 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02978447 0,06831404 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02978447 0,06824898 ! sterol catabolic process GO:0016127 11 9 0,000 0,02978447 0,06818405 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02978447 0,06811923 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02978447 0,06805454 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02978447 0,06798997 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02978447 0,06792553 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02978447 0,0678612 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02978447 0,067797 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02978447 0,06773292 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02978447 0,06766896 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02978447 0,06760512 ! purine base metabolic process GO:0006144 21 9 0,000 0,02978447 0,06754141 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02978447 0,06747781 ! pigment granule transport GO:0051904 17 9 0,000 0,02978447 0,06741433 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02978447 0,06735097 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02978447 0,06728773 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02978447 0,06722461 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02978447 0,0671616 ! mitochondrion localization GO:0051646 15 9 0,000 0,02978447 0,06709872 ! T cell activation GO:0042110 168 81 1,000 0,0303898 0,06839837 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,0303898 0,06833444 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,0303898 0,06827064 ! nuclear import GO:0051170 161 81 1,000 0,0303898 0,06820695 ! response to nutrient GO:0007584 125 82 1,000 0,03108265 0,06969699 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,03108265 0,06963209 ! hemostasis GO:0007599 158 84 1,000 0,03248704 0,07271053 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03303914 0,07387749 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03303914 0,0738089 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03303914 0,07374043 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03303914 0,07367209 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03303914 0,07360387 ! synapsis GO:0007129 13 10 0,000 0,03303914 0,07353578 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03303914 0,07346782 ! N-glycan processing GO:0006491 20 10 0,000 0,03303914 0,07339998 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03303914 0,07333227 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03303914 0,07326468 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03303914 0,07319722 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03303914 0,07312988 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03303914 0,07306267 ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03303914 0,07299557 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03303914 0,07292861 ! androgen metabolic process GO:0008209 17 10 0,000 0,03303914 0,07286176 ! phospholipid efflux GO:0033700 16 10 0,000 0,03303914 0,07279504 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03303914 0,07272844 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03303914 0,07266196 ! lung alveolus development GO:0048286 26 10 0,000 0,03303914 0,0725956 ! pathogenesis GO:0009405 13 10 0,000 0,03303914 0,07252936 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03303914 0,07246325 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03303914 0,07239725 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03303914 0,07233137 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03303914 0,07226562 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03303914 0,07219998 ! endoderm development GO:0007492 16 10 0,000 0,03303914 0,07213447 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03303914 0,07206907 ! arginine catabolic process GO:0006527 13 10 0,000 0,03303914 0,07200379 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03303914 0,07193863 ! proline metabolic process GO:0006560 13 10 0,000 0,03303914 0,07187358 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03303914 0,07180865 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03303914 0,07174385 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03303914 0,07167915 ! V(D)J recombination GO:0033151 28 10 0,000 0,03303914 0,07161458 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03303914 0,07155012 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03303914 0,07148577 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03303914 0,07142155 ! B cell proliferation GO:0042100 18 10 0,000 0,03303914 0,07135743 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03303914 0,07129344 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03303914 0,07122955 ! multicellular organism growth GO:0035264 18 10 0,000 0,03303914 0,07116578 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03303914 0,07110213 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03303914 0,07103859 ! epithelial cell development GO:0002064 20 10 0,000 0,03303914 0,07097516 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03303914 0,07091185 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03303914 0,07084865 ! macroautophagy GO:0016236 17 10 0,000 0,03303914 0,07078556 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03303914 0,07072258 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03303914 0,07065972 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03303914 0,07059696 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03303914 0,07053432 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,03303914 0,07047179 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03303914 0,07040937 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03303914 0,07034706 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03303914 0,07028486 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03303914 0,07022277 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03303914 0,07016079 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03303914 0,07009892 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03303914 0,07003716 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03303914 0,06997551 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03303914 0,06991397 ! response to dsRNA GO:0043331 20 10 0,000 0,03303914 0,06985253 ! DNA ligation GO:0006266 19 10 0,000 0,03303914 0,0697912 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03303914 0,06972998 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03303914 0,06966887 ! melanosome localization GO:0032400 16 10 0,000 0,03303914 0,06960786 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03303914 0,06954696 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03303914 0,06948617 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03303914 0,06942549 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03303914 0,0693649 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03303914 0,06930443 ! mRNA cleavage GO:0006379 17 10 0,000 0,03303914 0,06924406 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03303914 0,0691838 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03303914 0,06912364 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03303914 0,06906358 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03303914 0,06900363 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03303914 0,06894378 ! salivary gland development GO:0007431 27 10 0,000 0,03303914 0,06888404 ! prophase GO:0051324 15 10 0,000 0,03303914 0,0688244 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03303914 0,06876486 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03303914 0,06870543 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03303914 0,0686461 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03303914 0,06858687 ! midbrain development GO:0030901 13 10 0,000 0,03303914 0,06852774 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03303914 0,06846872 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03303914 0,06840979 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03303914 0,06835097 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03303914 0,06829225 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03303914 0,06823363 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03303914 0,06817511 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03303914 0,06811669 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,03303914 0,06805837 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,03303914 0,06800015 ! oocyte development GO:0048599 17 10 0,000 0,03303914 0,06794203 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03303914 0,06788401 ! blastocyst formation GO:0001825 17 10 0,000 0,03303914 0,06782609 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03303914 0,06776827 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03303914 0,06771055 ! activation of innate immune response GO:0002218 12 10 0,000 0,03303914 0,06765292 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03303914 0,06759539 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03303914 0,06753796 ! response to nicotine GO:0035094 20 10 0,000 0,03303914 0,06748063 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03303914 0,06742339 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03303914 0,06736625 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03303914 0,06730921 ! localization within membrane GO:0051668 20 10 0,000 0,03303914 0,06725227 ! response to unfolded protein GO:0006986 131 85 1,000 0,03319848 0,06751947 ! tube morphogenesis GO:0035239 176 86 1,000 0,03391601 0,06892054 ! mitochondrion organization GO:0007005 148 86 1,000 0,03391601 0,06886238 ! protein localization in nucleus GO:0034504 176 87 1,000 0,03463959 0,07027222 ! regulation of neurological system process GO:0031644 148 88 1,000 0,03536917 0,07169184 ! cellular defense response GO:0006968 114 89 1,000 0,0361047 0,07312114 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03628301 0,07342045 ! respiratory burst GO:0045730 17 11 0,000 0,03628301 0,07335876 ! neuron fate specification GO:0048665 17 11 0,000 0,03628301 0,07329716 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03628301 0,07323567 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03628301 0,07317428 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03628301 0,073113 ! thyroid gland development GO:0030878 26 11 0,000 0,03628301 0,07305182 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,03628301 0,07299074 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03628301 0,07292976 ! response to pain GO:0048265 24 11 0,000 0,03628301 0,07286888 ! T cell proliferation GO:0042098 26 11 0,000 0,03628301 0,07280811 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03628301 0,07274743 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03628301 0,07268686 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03628301 0,07262639 ! bone resorption GO:0045453 16 11 0,000 0,03628301 0,07256602 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,03628301 0,07250575 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03628301 0,07244558 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03628301 0,07238551 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03628301 0,07232553 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03628301 0,07226566 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03628301 0,07220589 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03628301 0,07214621 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03628301 0,07208664 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03628301 0,07202716 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03628301 0,07196778 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03628301 0,0719085 ! lipid digestion GO:0044241 18 11 0,000 0,03628301 0,07184932 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03628301 0,07179023 ! UV protection GO:0009650 19 11 0,000 0,03628301 0,07173124 ! adult heart development GO:0007512 14 11 0,000 0,03628301 0,07167235 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03628301 0,07161355 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03628301 0,07155485 ! temperature homeostasis GO:0001659 17 11 0,000 0,03628301 0,07149625 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03628301 0,07143774 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03628301 0,07137933 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03628301 0,07132101 ! regulation of organ growth GO:0046620 13 11 0,000 0,03628301 0,07126279 ! pigment granule localization GO:0051875 20 11 0,000 0,03628301 0,07120467 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03628301 0,07114663 ! vasoconstriction GO:0042310 18 11 0,000 0,03628301 0,0710887 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03628301 0,07103085 ! embryonic axis specification GO:0000578 18 11 0,000 0,03628301 0,07097311 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03628301 0,07091545 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03628301 0,07085789 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03628301 0,07080042 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03628301 0,07074305 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03628301 0,07068577 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03628301 0,07062858 ! zymogen activation GO:0031638 15 11 0,000 0,03628301 0,07057148 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03628301 0,07051448 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03628301 0,07045756 ! nucleosome positioning GO:0016584 15 11 0,000 0,03628301 0,07040074 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03628301 0,07034401 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03628301 0,07028738 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03628301 0,07023083 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03628301 0,07017437 ! acid secretion GO:0046717 18 11 0,000 0,03628301 0,07011801 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03628301 0,07006173 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03628301 0,07000555 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03628301 0,06994946 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03628301 0,06989345 ! oocyte differentiation GO:0009994 18 11 0,000 0,03628301 0,06983754 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03628301 0,06978171 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03628301 0,06972597 ! cholesterol efflux GO:0033344 19 11 0,000 0,03628301 0,06967033 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03628301 0,06961477 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03628301 0,0695593 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03628301 0,06950392 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03628301 0,06944862 ! embryonic gut development GO:0048566 15 11 0,000 0,03628301 0,06939342 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03628301 0,0693383 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03628301 0,06928327 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03628301 0,06922833 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03628301 0,06917347 ! defense response to fungus GO:0050832 13 11 0,000 0,03628301 0,0691187 ! developmental induction GO:0031128 19 11 0,000 0,03628301 0,06906402 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03628301 0,06900942 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03628301 0,06895491 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03628301 0,06890049 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03628301 0,06884615 ! nucleus localization GO:0051647 19 11 0,000 0,03628301 0,0687919 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03628301 0,06873773 ! ossification GO:0001503 188 90 1,000 0,03684614 0,06974966 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03684614 0,06969482 ! bone development GO:0060348 189 91 1,000 0,03759344 0,07105249 ! response to protein stimulus GO:0051789 149 91 1,000 0,03759344 0,07099671 ! regulation of defense response GO:0031347 149 92 1,000 0,03834655 0,07236219 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,03910542 0,0737364 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0395161 0,07445242 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0395161 0,07439416 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0395161 0,07433599 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0395161 0,07427792 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0395161 0,07421993 ! virus-host interaction GO:0019048 29 12 0,000 0,0395161 0,07416204 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,0395161 0,07410424 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0395161 0,07404652 ! cartilage condensation GO:0001502 20 12 0,000 0,0395161 0,0739889 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0395161 0,07393136 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0395161 0,07387392 ! protein complex disassembly GO:0043241 27 12 0,000 0,0395161 0,07381656 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0395161 0,0737593 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0395161 0,07370212 ! hippocampus development GO:0021766 26 12 0,000 0,0395161 0,07364503 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0395161 0,07358803 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0395161 0,07353112 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0395161 0,07347429 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0395161 0,07341756 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0395161 0,07336091 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0395161 0,07330434 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0395161 0,07324787 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0395161 0,07319148 ! drug transport GO:0015893 16 12 0,000 0,0395161 0,07313518 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0395161 0,07307897 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0395161 0,07302284 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0395161 0,0729668 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0395161 0,07291084 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0395161 0,07285497 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0395161 0,07279918 ! forebrain cell migration GO:0021885 21 12 0,000 0,0395161 0,07274349 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0395161 0,07268787 ! entry into host cell GO:0030260 32 12 0,000 0,0395161 0,07263234 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0395161 0,0725769 ! monoamine transport GO:0015844 18 12 0,000 0,0395161 0,07252154 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0395161 0,07246626 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0395161 0,07241107 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0395161 0,07235596 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0395161 0,07230094 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0395161 0,072246 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0395161 0,07219114 ! protein homotetramerization GO:0051289 21 12 0,000 0,0395161 0,07213637 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0395161 0,07208168 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0395161 0,07202707 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0395161 0,07197255 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0395161 0,07191811 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0395161 0,07186375 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0395161 0,07180947 ! cranial nerve development GO:0021545 20 12 0,000 0,0395161 0,07175527 ! fucose catabolic process GO:0019317 22 12 0,000 0,0395161 0,07170116 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0395161 0,07164713 ! histone acetylation GO:0016573 26 12 0,000 0,0395161 0,07159317 ! histone methylation GO:0016571 26 12 0,000 0,0395161 0,0715393 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0395161 0,07148552 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0395161 0,07143181 ! gland morphogenesis GO:0022612 29 12 0,000 0,0395161 0,07137818 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0395161 0,07132463 ! T cell homeostasis GO:0043029 25 12 0,000 0,0395161 0,07127117 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0395161 0,07121778 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0395161 0,07116447 ! spleen development GO:0048536 22 12 0,000 0,0395161 0,07111125 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0395161 0,0710581 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0395161 0,07100503 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0395161 0,07095204 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0395161 0,07089913 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0395161 0,0708463 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0395161 0,07079355 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0395161 0,07074087 ! response to cold GO:0009409 17 12 0,000 0,0395161 0,07068828 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0395161 0,07063576 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0395161 0,07058332 ! transcription initiation GO:0006352 153 94 1,000 0,03987002 0,07116266 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03987002 0,07110991 ! forebrain development GO:0030900 188 95 1,000 0,04064029 0,07243002 ! leukocyte differentiation GO:0002521 202 96 1,000 0,04141618 0,0737582 ! detection of stimulus GO:0051606 151 96 1,000 0,04141618 0,07370365 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04273845 0,07600053 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04273845 0,0759444 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04273845 0,07588835 ! peroxisomal transport GO:0043574 24 13 0,000 0,04273845 0,07583238 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04273845 0,0757765 ! lipid localization GO:0010876 28 13 0,000 0,04273845 0,0757207 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04273845 0,07566498 ! organelle fusion GO:0048284 32 13 0,000 0,04273845 0,07560935 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04273845 0,07555379 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04273845 0,07549832 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04273845 0,07544293 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04273845 0,07538762 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04273845 0,07533239 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04273845 0,07527724 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04273845 0,07522217 ! methionine metabolic process GO:0006555 27 13 0,000 0,04273845 0,07516719 ! plasma membrane organization GO:0007009 24 13 0,000 0,04273845 0,07511228 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04273845 0,07505745 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04273845 0,07500271 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04273845 0,07494804 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04273845 0,07489345 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04273845 0,07483895 ! response to X-ray GO:0010165 25 13 0,000 0,04273845 0,07478452 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04273845 0,07473017 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04273845 0,0746759 ! exocrine system development GO:0035272 32 13 0,000 0,04273845 0,07462171 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,04273845 0,07456759 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04273845 0,07451356 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04273845 0,0744596 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04273845 0,07440572 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04273845 0,07435192 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04273845 0,0742982 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04273845 0,07424456 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04273845 0,07419099 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04273845 0,0741375 ! regulation of cellular pH GO:0030641 22 13 0,000 0,04273845 0,07408409 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04273845 0,07403075 ! ribosome assembly GO:0042255 17 13 0,000 0,04273845 0,07397749 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,04273845 0,07392431 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04273845 0,0738712 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04273845 0,07381817 ! chromatin silencing GO:0006342 26 13 0,000 0,04273845 0,07376522 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04273845 0,07371234 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04273845 0,07365954 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04273845 0,07360681 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04273845 0,07355416 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04273845 0,07350158 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04273845 0,07344908 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04273845 0,07339665 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04273845 0,0733443 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04273845 0,07329203 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04273845 0,07323982 ! embryonic placenta development GO:0001892 23 13 0,000 0,04273845 0,0731877 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04273845 0,07313564 ! insulin secretion GO:0030073 23 13 0,000 0,04273845 0,07308366 ! actin filament polymerization GO:0030041 24 13 0,000 0,04273845 0,07303176 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04273845 0,07297992 ! acrosome reaction GO:0007340 18 13 0,000 0,04273845 0,07292816 ! response to virus GO:0009615 160 98 1,000 0,04298467 0,07329633 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,04377717 0,07459482 ! rRNA transcription GO:0009303 25 14 0,000 0,0459501 0,07824199 ! lactation GO:0007595 26 14 0,000 0,0459501 0,07818666 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0459501 0,0781314 ! reproductive cellular process GO:0048610 20 14 0,000 0,0459501 0,07807622 ! tRNA modification GO:0006400 20 14 0,000 0,0459501 0,07802112 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0459501 0,0779661 ! regulation of S phase GO:0033261 23 14 0,000 0,0459501 0,07791116 ! water transport GO:0006833 21 14 0,000 0,0459501 0,07785629 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0459501 0,0778015 ! non-recombinational repair GO:0000726 25 14 0,000 0,0459501 0,07774679 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0459501 0,07769215 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0459501 0,07763759 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0459501 0,07758311 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0459501 0,07752871 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0459501 0,07747438 ! palate development GO:0060021 31 14 0,000 0,0459501 0,07742012 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0459501 0,07736594 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0459501 0,07731184 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0459501 0,07725782 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0459501 0,07720386 ! arginine metabolic process GO:0006525 17 14 0,000 0,0459501 0,07714999 ! regulation of heart rate GO:0002027 24 14 0,000 0,0459501 0,07709619 ! organic alcohol transport GO:0015850 29 14 0,000 0,0459501 0,07704246 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0459501 0,07698881 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0459501 0,07693524 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0459501 0,07688173 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0459501 0,07682831 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0459501 0,07677495 ! L-amino acid transport GO:0015807 30 14 0,000 0,0459501 0,07672168 ! bone mineralization GO:0030282 17 14 0,000 0,0459501 0,07666847 ! stem cell development GO:0048864 43 14 0,000 0,0459501 0,07661534 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0459501 0,07656228 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0459501 0,0765093 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0459501 0,07645639 ! cerebellum development GO:0021549 21 14 0,000 0,0459501 0,07640355 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0459501 0,07635078 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0459501 0,07629809 ! response to gamma radiation GO:0010332 28 14 0,000 0,0459501 0,07624547 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0459501 0,07619292 ! cofactor transport GO:0051181 26 14 0,000 0,0459501 0,07614045 ! NADP metabolic process GO:0006739 24 14 0,000 0,0459501 0,07608805 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0459501 0,07603572 ! intestinal absorption GO:0050892 25 14 0,000 0,0459501 0,07598346 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0459501 0,07593127 ! oxygen transport GO:0015671 21 14 0,000 0,0459501 0,07587916 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0459501 0,07582712 ! male genitalia development GO:0030539 24 14 0,000 0,0459501 0,07577514 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0459501 0,07572324 ! regulation of axon extension GO:0030516 37 14 0,000 0,0459501 0,07567141 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0459501 0,07561965 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04915108 0,08083219 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04915108 0,08077697 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04915108 0,08072183 ! superoxide anion generation GO:0042554 20 15 0,000 0,04915108 0,08066677 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04915108 0,08061178 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04915108 0,08055687 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04915108 0,08050203 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04915108 0,08044727 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04915108 0,08039258 ! sulfate transport GO:0008272 23 15 0,000 0,04915108 0,08033797 ! response to cAMP GO:0051591 22 15 0,000 0,04915108 0,08028343 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04915108 0,08022896 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04915108 0,08017457 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04915108 0,08012025 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04915108 0,080066 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04915108 0,08001183 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04915108 0,07995773 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04915108 0,07990371 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04915108 0,07984975 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04915108 0,07979588 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04915108 0,07974207 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04915108 0,07968833 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04915108 0,07963467 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04915108 0,07958108 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04915108 0,07952756 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04915108 0,07947412 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04915108 0,07942074 ! histone deacetylation GO:0016575 20 15 0,000 0,04915108 0,07936744 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04915108 0,07931421 ! tissue regeneration GO:0042246 26 15 0,000 0,04915108 0,07926105 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04915108 0,07920796 ! water homeostasis GO:0030104 27 15 0,000 0,04915108 0,07915494 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04915108 0,079102 ! muscle maintenance GO:0046716 26 15 0,000 0,04915108 0,07904912 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04915108 0,07899632 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04915108 0,07894358 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04915108 0,07889092 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04915108 0,07883832 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04915108 0,0787858 ! cell killing GO:0001906 29 15 0,000 0,04915108 0,07873335 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04915108 0,07868096 ! detection of bacterium GO:0016045 18 15 0,000 0,04915108 0,07862865 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04915108 0,0785764 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04915108 0,07852423 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04915108 0,07847212 ! peptide hormone processing GO:0016486 23 15 0,000 0,04915108 0,07842008 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,05234142 0,08345491 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,05234142 0,08339964 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05234142 0,08334444 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05234142 0,08328932 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05234142 0,08323427 ! bone remodeling GO:0046849 27 16 0,000 0,05234142 0,0831793 ! filopodium assembly GO:0046847 32 16 0,000 0,05234142 0,08312439 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05234142 0,08306956 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05234142 0,0830148 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05234142 0,08296012 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05234142 0,0829055 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05234142 0,08285096 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05234142 0,08279649 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05234142 0,08274209 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05234142 0,08268776 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05234142 0,0826335 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05234142 0,08257931 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05234142 0,0825252 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05234142 0,08247116 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05234142 0,08241718 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05234142 0,08236328 ! response to osmotic stress GO:0006970 25 16 0,000 0,05234142 0,08230945 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05234142 0,08225569 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05234142 0,08220199 ! fructose metabolic process GO:0006000 25 16 0,000 0,05234142 0,08214837 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05234142 0,08209482 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05234142 0,08204134 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05234142 0,08198793 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05234142 0,08193458 ! axon cargo transport GO:0008088 43 16 0,000 0,05234142 0,08188131 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05234142 0,08182811 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05234142 0,08177497 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,05234142 0,0817219 ! neuron recognition GO:0008038 35 16 0,000 0,05234142 0,08166891 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05234142 0,08161598 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05234142 0,08156312 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05234142 0,08151033 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05234142 0,0814576 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05234142 0,08140495 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05234142 0,08135236 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05234142 0,08129984 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05234142 0,08124739 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05234142 0,08119501 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05234142 0,08114269 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05234142 0,08109044 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,05234142 0,08103826 ! defense response to virus GO:0051607 37 16 0,000 0,05234142 0,08098614 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05552116 0,08585085 ! metencephalon development GO:0022037 30 17 0,000 0,05552116 0,08579571 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05552116 0,08574064 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05552116 0,08568565 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05552116 0,08563072 ! signal complex assembly GO:0007172 41 17 0,000 0,05552116 0,08557586 ! endothelial cell migration GO:0043542 28 17 0,000 0,05552116 0,08552108 ! inositol metabolic process GO:0006020 28 17 0,000 0,05552116 0,08546636 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05552116 0,08541172 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05552116 0,08535714 ! glial cell development GO:0021782 27 17 0,000 0,05552116 0,08530263 ! limbic system development GO:0021761 36 17 0,000 0,05552116 0,0852482 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05552116 0,08519383 ! adult walking behavior GO:0007628 33 17 0,000 0,05552116 0,08513953 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05552116 0,0850853 ! heart looping GO:0001947 30 17 0,000 0,05552116 0,08503114 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05552116 0,08497705 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05552116 0,08492303 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05552116 0,08486907 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05552116 0,08481519 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05552116 0,08476137 ! glycine metabolic process GO:0006544 28 17 0,000 0,05552116 0,08470762 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,05552116 0,08465394 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05552116 0,08460033 ! NAD metabolic process GO:0019674 29 17 0,000 0,05552116 0,08454679 ! DNA integration GO:0015074 29 17 0,000 0,05552116 0,08449331 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05552116 0,0844399 ! regulation of protein binding GO:0043393 33 17 0,000 0,05552116 0,08438656 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05552116 0,08433328 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05552116 0,08428008 ! genitalia development GO:0048806 30 17 0,000 0,05552116 0,08422694 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05552116 0,08417386 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05552116 0,08412086 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05552116 0,08406792 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05552116 0,08401505 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05552116 0,08396224 ! steroid catabolic process GO:0006706 31 17 0,000 0,05552116 0,0839095 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05552116 0,08385683 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05552116 0,08380422 ! gas transport GO:0015669 25 17 0,000 0,05552116 0,08375168 ! organic cation transport GO:0015695 31 17 0,000 0,05552116 0,0836992 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05552116 0,08364679 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05552116 0,08359444 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05552116 0,08354217 ! microspike assembly GO:0030035 36 17 0,000 0,05552116 0,08348995 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05552116 0,0834378 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05552116 0,08338572 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05869035 0,08809044 ! neuron maturation GO:0042551 42 18 0,000 0,05869035 0,08803552 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05869035 0,08798067 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,05869035 0,08792589 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05869035 0,08787117 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05869035 0,08781653 ! memory GO:0007613 31 18 0,000 0,05869035 0,08776195 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05869035 0,08770744 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05869035 0,08765299 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05869035 0,08759862 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05869035 0,08754431 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05869035 0,08749007 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05869035 0,0874359 ! response to retinoic acid GO:0032526 26 18 0,000 0,05869035 0,08738179 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05869035 0,08732775 ! response to fungus GO:0009620 21 18 0,000 0,05869035 0,08727378 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05869035 0,08721987 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05869035 0,08716603 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05869035 0,08711226 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05869035 0,08705855 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05869035 0,08700491 ! vitamin transport GO:0051180 27 18 0,000 0,05869035 0,08695134 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05869035 0,08689783 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05869035 0,08684439 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05869035 0,08679101 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05869035 0,0867377 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,05869035 0,08668445 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05869035 0,08663127 ! nerve development GO:0021675 28 18 0,000 0,05869035 0,08657816 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05869035 0,08652511 ! protein secretion GO:0009306 39 19 0,000 0,061849 0,09112596 ! positive regulation of translation GO:0045727 30 19 0,000 0,061849 0,09107019 ! negative regulation of defense response GO:0031348 25 19 0,000 0,061849 0,09101449 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,061849 0,09095886 ! skin development GO:0043588 36 19 0,000 0,061849 0,09090329 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,061849 0,0908478 ! lipid phosphorylation GO:0046834 35 19 0,000 0,061849 0,09079237 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,061849 0,09073701 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,061849 0,09068171 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,061849 0,09062649 ! bile acid metabolic process GO:0008206 29 19 0,000 0,061849 0,09057133 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,061849 0,09051624 ! cerebral cortex development GO:0021987 36 19 0,000 0,061849 0,09046121 ! pigmentation during development GO:0048066 41 19 0,000 0,061849 0,09040625 ! response to vitamin A GO:0033189 27 19 0,000 0,061849 0,09035136 ! heme metabolic process GO:0042168 36 19 0,000 0,061849 0,09029654 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,061849 0,09024178 ! plasma membrane fusion GO:0045026 28 19 0,000 0,061849 0,09018709 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,061849 0,09013246 ! peptide cross-linking GO:0018149 37 19 0,000 0,061849 0,0900779 ! protein export from nucleus GO:0006611 36 19 0,000 0,061849 0,09002341 ! heart process GO:0003015 30 19 0,000 0,061849 0,08996898 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,061849 0,08991462 ! visual learning GO:0008542 36 19 0,000 0,061849 0,08986032 ! G1 phase GO:0051318 40 19 0,000 0,061849 0,08980609 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,061849 0,08975192 ! cell-cell junction organization GO:0045216 35 19 0,000 0,061849 0,08969782 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,061849 0,08964379 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,061849 0,08958982 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,061849 0,08953591 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,061849 0,08948207 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,061849 0,0894283 ! cilium assembly GO:0042384 37 19 0,000 0,061849 0,08937459 ! peptide hormone secretion GO:0030072 31 19 0,000 0,061849 0,08932094 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06499716 0,09381113 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06499716 0,09375489 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06499716 0,09369872 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06499716 0,09364261 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06499716 0,09358657 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,06499716 0,0935306 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,06499716 0,09347469 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06499716 0,09341885 ! response to vitamin GO:0033273 31 20 0,000 0,06499716 0,09336308 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06499716 0,09330737 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,06499716 0,09325173 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06499716 0,09319616 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06499716 0,09314065 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06499716 0,09308521 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06499716 0,09302984 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06499716 0,09297453 ! cellular response to starvation GO:0009267 33 20 0,000 0,06499716 0,09291929 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,06499716 0,09286411 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06499716 0,092809 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06499716 0,09275395 ! body fluid secretion GO:0007589 31 20 0,000 0,06499716 0,09269897 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06499716 0,09264405 ! peptide secretion GO:0002790 35 20 0,000 0,06499716 0,0925892 ! stem cell differentiation GO:0048863 53 20 0,000 0,06499716 0,09253441 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06499716 0,09247969 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06499716 0,09242503 ! sensory perception of pain GO:0019233 30 20 0,000 0,06499716 0,09237044 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06499716 0,09231591 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06499716 0,09226145 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06499716 0,09220705 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06499716 0,09215272 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,06499716 0,09209844 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06499716 0,09204424 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06499716 0,09199009 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06499716 0,09193601 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06499716 0,091882 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06499716 0,09182804 ! regulation of glucose import GO:0046324 29 20 0,000 0,06499716 0,09177415 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06499716 0,09172033 ! actin filament-based movement GO:0030048 43 20 0,000 0,06499716 0,09166656 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06499716 0,09161286 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06499716 0,09155923 ! negative regulation of translation GO:0017148 29 20 0,000 0,06499716 0,09150565 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06499716 0,09145214 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,06499716 0,09139869 ! regulation of cell killing GO:0031341 42 21 0,000 0,06813485 0,09575494 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06813485 0,09569904 ! hormone secretion GO:0046879 38 21 0,000 0,06813485 0,09564321 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06813485 0,09558744 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06813485 0,09553174 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06813485 0,0954761 ! axis specification GO:0009798 38 21 0,000 0,06813485 0,09542052 ! ovarian follicle development GO:0001541 35 21 0,000 0,06813485 0,09536501 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06813485 0,09530957 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06813485 0,09525419 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06813485 0,09519887 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06813485 0,09514362 ! cell aging GO:0007569 44 21 0,000 0,06813485 0,09508843 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06813485 0,09503331 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06813485 0,09497825 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06813485 0,09492325 ! cytolysis GO:0019835 24 21 0,000 0,06813485 0,09486832 ! vasodilation GO:0042311 39 21 0,000 0,06813485 0,09481345 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06813485 0,09475865 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06813485 0,0947039 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06813485 0,09464923 ! oogenesis GO:0048477 36 21 0,000 0,06813485 0,09459461 ! DNA modification GO:0006304 34 21 0,000 0,06813485 0,09454006 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,06813485 0,09448557 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,06813485 0,09443114 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06813485 0,09437678 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06813485 0,09432247 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06813485 0,09426823 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06813485 0,09421406 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06813485 0,09415994 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06813485 0,09410589 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06813485 0,0940519 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06813485 0,09399797 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06813485 0,0939441 ! gut development GO:0048565 39 21 0,000 0,06813485 0,0938903 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,07126213 0,09814349 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,07126213 0,09808734 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07126213 0,09803126 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07126213 0,09797524 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,07126213 0,09791929 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,07126213 0,0978634 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,07126213 0,09780757 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07126213 0,09775181 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07126213 0,09769611 ! regeneration GO:0031099 41 22 0,000 0,07126213 0,09764048 ! keratinization GO:0031424 28 22 0,000 0,07126213 0,0975849 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,07126213 0,09752939 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07126213 0,09747395 ! sensory perception of taste GO:0050909 28 22 0,000 0,07126213 0,09741857 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07126213 0,09736325 ! vacuolar transport GO:0007034 36 22 0,000 0,07126213 0,09730799 ! lysosome organization GO:0007040 41 22 0,000 0,07126213 0,09725279 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07126213 0,09719766 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,07126213 0,09714259 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,07126213 0,09708759 ! fucose metabolic process GO:0006004 39 22 0,000 0,07126213 0,09703264 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07126213 0,09697776 ! ureteric bud development GO:0001657 43 22 0,000 0,07126213 0,09692294 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,07126213 0,09686818 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,07126213 0,09681348 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07126213 0,09675885 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,07126213 0,09670427 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07126213 0,09664976 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07126213 0,09659531 ! sarcomere organization GO:0045214 30 22 0,000 0,07126213 0,09654092 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,07126213 0,09648659 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07126213 0,09643233 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07126213 0,09637812 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07126213 0,09632397 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07126213 0,09626989 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,07126213 0,09621587 ! protein stabilization GO:0050821 39 22 0,000 0,07126213 0,0961619 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,07437901 0,1003116 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07437901 0,1002554 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07437901 0,10019927 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07437901 0,1001432 ! gluconeogenesis GO:0006094 33 23 0,000 0,07437901 0,10008719 ! viral genome replication GO:0019079 41 23 0,000 0,07437901 0,10003124 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07437901 0,09997536 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07437901 0,09991954 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07437901 0,09986378 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07437901 0,09980808 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07437901 0,09975245 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07437901 0,09969687 ! visual behavior GO:0007632 42 23 0,000 0,07437901 0,09964136 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,07437901 0,09958592 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,07437901 0,09953053 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07437901 0,0994752 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,07437901 0,09941994 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07437901 0,09936474 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07437901 0,0993096 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07437901 0,09925451 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,07437901 0,0991995 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,07437901 0,09914454 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07437901 0,09908964 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07437901 0,0990348 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07437901 0,09898003 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07437901 0,09892531 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07437901 0,09887066 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07437901 0,09881606 ! fatty acid transport GO:0015908 44 23 0,000 0,07437901 0,09876153 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07437901 0,09870705 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07437901 0,09865264 ! hormone transport GO:0009914 40 23 0,000 0,07437901 0,09859829 ! cell-cell recognition GO:0009988 25 23 0,000 0,07437901 0,09854399 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07437901 0,09848976 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07437901 0,09843558 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07437901 0,09838147 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07437901 0,09832741 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07437901 0,09827342 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,07748553 0,10232173 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,07748553 0,1022656 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07748553 0,10220953 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,07748553 0,10215353 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07748553 0,10209758 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07748553 0,1020417 ! vesicle docking GO:0048278 47 24 0,000 0,07748553 0,10198588 ! spinal cord development GO:0021510 47 24 0,000 0,07748553 0,10193012 ! vacuole organization GO:0007033 43 24 0,000 0,07748553 0,10187442 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07748553 0,10181878 ! digestive system process GO:0022600 39 24 0,000 0,07748553 0,1017632 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07748553 0,10170768 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07748553 0,10165223 ! regulation of behavior GO:0050795 43 24 0,000 0,07748553 0,10159683 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07748553 0,1015415 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07748553 0,10148622 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07748553 0,101431 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07748553 0,10137585 ! membrane depolarization GO:0051899 39 24 0,000 0,07748553 0,10132075 ! pallium development GO:0021543 49 24 0,000 0,07748553 0,10126572 ! pentose metabolic process GO:0019321 35 24 0,000 0,07748553 0,10121074 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,07748553 0,10115583 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07748553 0,10110097 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07748553 0,10104617 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07748553 0,10099143 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07748553 0,10093675 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07748553 0,10088214 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07748553 0,10082757 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07748553 0,10077307 ! regulation of amine transport GO:0051952 40 24 0,000 0,07748553 0,10071863 ! protein tetramerization GO:0051262 52 24 0,000 0,07748553 0,10066425 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,08058173 0,10463014 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,08058173 0,1045737 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,08058173 0,10451733 ! phototransduction GO:0007602 33 25 0,000 0,08058173 0,10446102 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,08058173 0,10440476 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,08058173 0,10434857 ! sperm motility GO:0030317 31 25 0,000 0,08058173 0,10429244 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,08058173 0,10423637 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,08058173 0,10418036 ! receptor metabolic process GO:0043112 46 25 0,000 0,08058173 0,10412441 ! chromosome condensation GO:0030261 45 25 0,000 0,08058173 0,10406852 ! response to starvation GO:0042594 42 25 0,000 0,08058173 0,10401268 ! neural crest cell development GO:0014032 54 25 0,000 0,08058173 0,10395691 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,08058173 0,1039012 ! negative regulation of cell development GO:0010721 73 25 0,000 0,08058173 0,10384555 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,08058173 0,10378996 ! interaction with host GO:0051701 62 25 0,000 0,08058173 0,10373443 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,08058173 0,10367895 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,08058173 0,10362354 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,08058173 0,10356819 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,08058173 0,10351289 ! immunoglobulin production GO:0002377 55 25 0,000 0,08058173 0,10345765 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,08058173 0,10340248 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,08058173 0,10334736 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,08058173 0,1032923 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,08058173 0,1032373 ! telomere organization GO:0032200 43 25 0,000 0,08058173 0,10318235 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,08058173 0,10312747 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,08058173 0,10307264 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08366764 0,10696299 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08366764 0,10690619 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,08366764 0,10684944 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,08366764 0,10679276 ! initiation of viral infection GO:0019059 57 26 0,000 0,08366764 0,10673613 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08366764 0,10667957 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08366764 0,10662307 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08366764 0,10656662 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08366764 0,10651024 ! tube lumen formation GO:0035148 50 26 0,000 0,08366764 0,10645391 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08366764 0,10639765 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,08366764 0,10634144 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,08366764 0,10628529 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,08366764 0,10622921 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,08366764 0,10617318 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,08366764 0,10611721 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08366764 0,1060613 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,08366764 0,10600545 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08366764 0,10594966 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,08366764 0,10589392 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08366764 0,10583825 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08366764 0,10578263 ! blastocyst development GO:0001824 49 26 0,000 0,08366764 0,10572707 ! leukocyte proliferation GO:0070661 52 26 0,000 0,08366764 0,10567157 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08366764 0,10561613 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,08366764 0,10556075 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,0867433 0,10938384 ! neuron fate commitment GO:0048663 48 27 0,000 0,0867433 0,10932655 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0867433 0,10926931 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0867433 0,10921213 ! iron ion transport GO:0006826 59 27 0,000 0,0867433 0,10915501 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,0867433 0,10909795 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0867433 0,10904095 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0867433 0,10898401 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0867433 0,10892713 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0867433 0,10887031 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0867433 0,10881354 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0867433 0,10875684 ! autophagy GO:0006914 41 27 0,000 0,0867433 0,1087002 ! male gonad development GO:0008584 44 27 0,000 0,0867433 0,10864361 ! response to toxin GO:0009636 47 27 0,000 0,0867433 0,10858708 ! primary neural tube formation GO:0014020 51 27 0,000 0,0867433 0,10853062 ! base-excision repair GO:0006284 41 27 0,000 0,0867433 0,10847421 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0867433 0,10841786 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0867433 0,10836157 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0867433 0,10830533 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0867433 0,10824916 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0867433 0,10819304 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0867433 0,10813698 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08980873 0,11190047 ! circadian rhythm GO:0007623 50 28 0,000 0,08980873 0,11184255 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08980873 0,11178469 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08980873 0,11172689 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08980873 0,11166915 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08980873 0,11161147 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08980873 0,11155385 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08980873 0,11149629 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08980873 0,11143879 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08980873 0,11138135 ! synaptogenesis GO:0007416 42 28 0,000 0,08980873 0,11132396 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,08980873 0,11126664 ! lipid oxidation GO:0034440 43 28 0,000 0,08980873 0,11120937 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08980873 0,11115217 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08980873 0,11109502 ! translational initiation GO:0006413 65 29 0,000 0,09286398 0,11481538 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,09286398 0,11475641 ! regulation of pH GO:0006885 43 29 0,000 0,09286398 0,1146975 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,09286398 0,11463865 ! catechol metabolic process GO:0009712 54 29 0,000 0,09286398 0,11457986 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,09286398 0,11452114 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,09286398 0,11446247 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,09286398 0,11440386 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,09286398 0,11434531 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,09286398 0,11428682 ! cell fate determination GO:0001709 60 29 0,000 0,09286398 0,11422839 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,09286398 0,11417002 ! detection of light stimulus GO:0009583 38 29 0,000 0,09286398 0,11411171 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,09286398 0,11405346 ! tissue homeostasis GO:0001894 48 29 0,000 0,09286398 0,11399527 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,09286398 0,11393714 ! phenol metabolic process GO:0018958 55 30 0,000 0,09590907 0,11761327 ! zinc ion transport GO:0006829 45 30 0,000 0,09590907 0,11755335 ! membrane docking GO:0022406 61 30 0,000 0,09590907 0,1174935 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09590907 0,1174337 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09590907 0,11737397 ! acute-phase response GO:0006953 49 30 0,000 0,09590907 0,1173143 ! myofibril assembly GO:0030239 47 30 0,000 0,09590907 0,11725469 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,09590907 0,11719514 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09590907 0,11713565 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,09590907 0,11707622 ! phospholipid transport GO:0015914 51 30 0,000 0,09590907 0,11701685 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,09590907 0,11695754 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,09590907 0,11689829 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09590907 0,1168391 ! eye morphogenesis GO:0048592 60 30 0,000 0,09590907 0,11677997 ! regulation of B cell activation GO:0050864 50 30 0,000 0,09590907 0,1167209 ! response to heat GO:0009408 50 30 0,000 0,09590907 0,11666189 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09894404 0,12029276 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09894404 0,120232 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09894404 0,12017131 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09894404 0,12011068 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09894404 0,12005011 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09894404 0,1199896 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09894404 0,11992915 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09894404 0,11986877 ! ovulation cycle process GO:0022602 49 31 0,000 0,09894404 0,11980844 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09894404 0,11974817 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09894404 0,11968797 ! peptide transport GO:0015833 55 31 0,000 0,09894404 0,11962782 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09894404 0,11956774 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09894404 0,11950771 ! mesoderm formation GO:0001707 69 31 0,000 0,09894404 0,11944775 ! natural killer cell activation GO:0030101 45 31 0,000 0,09894404 0,11938785 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09894404 0,119328 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09894404 0,11926822 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09894404 0,1192085 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,10196893 0,12279141 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,10196893 0,12272998 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,10196893 0,12266862 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,10196893 0,12260732 ! cholesterol transport GO:0030301 56 32 0,000 0,10196893 0,12254607 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,10196893 0,12248489 ! spliceosome assembly GO:0000245 67 32 0,000 0,10196893 0,12242377 ! spindle organization GO:0007051 46 32 0,000 0,10196893 0,12236271 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,10196893 0,12230171 ! metanephros development GO:0001656 74 32 0,000 0,10196893 0,12224078 ! response to ionizing radiation GO:0010212 65 32 0,000 0,10196893 0,1221799 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,10196893 0,12211908 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,10196893 0,12205833 ! muscle cell development GO:0055001 49 32 0,000 0,10196893 0,12199763 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,10196893 0,121937 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,10196893 0,12187642 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,10196893 0,12181591 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,10196893 0,12175545 ! ovulation cycle GO:0042698 51 32 0,000 0,10196893 0,12169506 ! BMP signaling pathway GO:0030509 64 32 0,000 0,10196893 0,12163472 ! hindbrain development GO:0030902 61 32 0,000 0,10196893 0,12157445 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,10196893 0,12151423 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,10196893 0,12145408 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,10196893 0,12139398 ! gene silencing GO:0016458 65 32 0,000 0,10196893 0,12133395 ! post-embryonic development GO:0009791 69 33 0,000 0,10498376 0,12485957 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,10498376 0,12479788 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10498376 0,12473626 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10498376 0,12467469 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10498376 0,12461318 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10498376 0,12455173 ! cell fate specification GO:0001708 52 33 0,000 0,10498376 0,12449035 ! sterol transport GO:0015918 57 33 0,000 0,10498376 0,12442902 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10498376 0,12436776 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10498376 0,12430655 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,10498376 0,12424541 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,10798856 0,12773869 ! glial cell differentiation GO:0010001 63 34 0,000 0,10798856 0,12767591 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10798856 0,12761321 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10798856 0,12755056 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10798856 0,12748797 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10798856 0,12742545 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10798856 0,12736298 ! mismatch repair GO:0006298 46 34 0,000 0,10798856 0,12730058 ! spermatid development GO:0007286 63 34 0,000 0,10798856 0,12723824 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10798856 0,12717596 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10798856 0,12711374 ! placenta development GO:0001890 53 34 0,000 0,10798856 0,12705158 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,10798856 0,12698948 ! regulation of muscle development GO:0048634 70 35 0,000 0,11098338 0,13044749 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,11098338 0,1303838 ! negative regulation of secretion GO:0051048 63 35 0,000 0,11098338 0,13032017 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,11098338 0,1302566 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,11098338 0,13019309 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,11098338 0,13012964 ! odontogenesis GO:0042476 66 35 0,000 0,11098338 0,13006625 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,11098338 0,13000293 ! female gonad development GO:0008585 58 35 0,000 0,11098338 0,12993967 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,11098338 0,12987647 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,11098338 0,12981333 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,11098338 0,12975025 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,11098338 0,12968724 ! cytokine production GO:0001816 59 35 0,000 0,11098338 0,12962428 ! neural tube formation GO:0001841 67 35 0,000 0,11098338 0,12956139 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,11396825 0,13298138 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,11396825 0,13291692 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,11396825 0,13285252 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,11396825 0,13278819 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,11396825 0,13272391 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,11396825 0,1326597 ! positive regulation of cell development GO:0010720 80 36 0,000 0,11396825 0,13259555 ! regulation of proteolysis GO:0030162 72 36 0,000 0,11396825 0,13253147 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,11396825 0,13246744 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,11396825 0,13240348 ! aerobic respiration GO:0009060 55 36 0,000 0,11396825 0,13233958 ! embryonic organ development GO:0048568 57 36 0,000 0,11396825 0,13227574 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,11396825 0,13221196 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11694319 0,13559774 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11694319 0,13553242 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,11694319 0,13546717 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11694319 0,13540198 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11694319 0,13533685 ! organic anion transport GO:0015711 68 37 0,000 0,11694319 0,13527178 ! tissue remodeling GO:0048771 76 37 0,000 0,11694319 0,13520678 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,11694319 0,13514184 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11694319 0,13507696 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11694319 0,13501215 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11694319 0,13494739 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,11694319 0,1348827 ! glycogen metabolic process GO:0005977 61 37 0,000 0,11694319 0,13481807 ! pigment metabolic process GO:0042440 80 37 0,000 0,11694319 0,1347535 ! spermatid differentiation GO:0048515 66 37 0,000 0,11694319 0,134689 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11990824 0,13803791 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11990824 0,13797189 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11990824 0,13790594 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11990824 0,13784005 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11990824 0,13777422 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,11990824 0,13770846 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11990824 0,13764276 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11990824 0,13757712 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11990824 0,13751155 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11990824 0,13744603 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,11990824 0,13738058 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11990824 0,1373152 ! glucan metabolic process GO:0044042 62 38 0,000 0,11990824 0,13724987 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,12286343 0,14056558 ! learning GO:0007612 77 39 0,000 0,12286343 0,14049877 ! organic ether metabolic process GO:0018904 55 39 0,000 0,12286343 0,14043203 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,12286343 0,14036535 ! segmentation GO:0035282 67 39 0,000 0,12286343 0,14029873 ! ion transmembrane transport GO:0034220 66 39 0,000 0,12286343 0,14023217 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,12286343 0,14016568 ! RNA modification GO:0009451 57 39 0,000 0,12286343 0,14009925 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,12286343 0,14003289 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,1258088 0,14332196 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,1258088 0,14325413 ! feeding behavior GO:0007631 59 40 0,000 0,1258088 0,14318637 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,1258088 0,14311867 ! maintenance of protein location GO:0045185 91 40 0,000 0,1258088 0,14305103 ! cytokinesis GO:0000910 72 40 0,000 0,1258088 0,14298346 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12874438 0,1462507 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12874438 0,14618168 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12874438 0,14611272 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12874438 0,14604383 ! gliogenesis GO:0042063 88 41 0,000 0,12874438 0,14597501 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12874438 0,14590625 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,12874438 0,14583756 ! female gamete generation GO:0007292 61 41 0,000 0,12874438 0,14576893 ! polyol metabolic process GO:0019751 66 41 0,000 0,12874438 0,14570036 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12874438 0,14563186 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,13167019 0,14887147 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,13167019 0,14880154 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,13167019 0,14873168 ! regulation of tube size GO:0035150 71 42 0,000 0,13167019 0,14866189 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,13167019 0,14859216 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,13167019 0,1485225 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,13167019 0,1484529 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,13167019 0,14838337 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,13167019 0,1483139 ! neuron migration GO:0001764 79 42 0,000 0,13167019 0,14824449 ! regulation of protein secretion GO:0050708 71 42 0,000 0,13167019 0,14817516 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,13458628 0,15138597 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,13458628 0,15131523 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,13458628 0,15124455 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,13458628 0,15117394 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,13458628 0,1511034 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,13458628 0,15103292 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,13458628 0,15096251 ! neural tube development GO:0021915 77 43 0,000 0,13458628 0,15089217 ! striated muscle contraction GO:0006941 77 43 0,000 0,13458628 0,15082189 ! phagocytosis GO:0006909 90 43 0,000 0,13458628 0,15075167 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,13458628 0,15068152 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13749267 0,15386389 ! male sex differentiation GO:0046661 76 44 0,000 0,13749267 0,15379236 ! biopolymer methylation GO:0043414 84 44 0,000 0,13749267 0,15372089 ! B cell differentiation GO:0030183 107 44 0,000 0,13749267 0,1536495 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,13749267 0,15357816 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,13749267 0,1535069 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,1403894 0,15666832 ! glycolysis GO:0006096 65 45 0,000 0,1403894 0,15659568 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,1403894 0,15652312 ! leukocyte migration GO:0050900 68 45 0,000 0,1403894 0,15645062 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,1403894 0,15637819 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,1403894 0,15630582 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,1403894 0,15623353 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,1403894 0,1561613 ! cell growth GO:0016049 84 45 0,000 0,1403894 0,15608913 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,14327649 0,15922551 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,14327649 0,159152 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,14327649 0,15907856 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,14327649 0,15900518 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,14327649 0,15893187 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,14327649 0,15885863 ! positive regulation of defense response GO:0031349 76 47 0,000 0,14615398 0,16197443 ! endosome transport GO:0016197 108 47 0,000 0,14615398 0,16189985 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,14615398 0,16182535 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,14615398 0,16175091 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,14615398 0,16167654 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,14615398 0,16160224 ! JNK cascade GO:0007254 91 47 0,000 0,14615398 0,16152801 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,14615398 0,16145385 ! methylation GO:0032259 90 47 0,000 0,14615398 0,16137975 ! mitochondrial transport GO:0006839 82 48 0,000 0,14902191 0,16447096 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14902191 0,16439555 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,14902191 0,16432021 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14902191 0,16424494 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14902191 0,16416974 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,15188029 0,1672421 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,15188029 0,16716559 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,15188029 0,16708915 ! regulation of ion transport GO:0043269 77 49 0,000 0,15188029 0,16701279 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,15188029 0,16693649 ! peptide metabolic process GO:0006518 76 49 0,000 0,15188029 0,16686026 ! response to temperature stimulus GO:0009266 76 49 0,000 0,15188029 0,16678411 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,15188029 0,16670802 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,15188029 0,166632 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,15472917 0,16968021 ! inner ear development GO:0048839 79 50 0,000 0,15472917 0,16960291 ! histone modification GO:0016570 91 50 0,000 0,15472917 0,16952567 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,15472917 0,16944851 ! positive regulation of binding GO:0051099 78 51 0,000 0,15756857 0,17247952 ! viral infectious cycle GO:0019058 99 51 0,000 0,15756857 0,17240109 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15756857 0,17232272 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15756857 0,17224443 ! excretion GO:0007588 83 51 0,000 0,15756857 0,17216621 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,15756857 0,17208806 ! chromatin remodeling GO:0006338 109 51 0,000 0,15756857 0,17200998 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,15756857 0,17193197 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,15756857 0,17185403 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,15756857 0,17177616 ! membrane fusion GO:0006944 110 52 0,000 0,16039853 0,1747821 ! positive regulation of growth GO:0045927 90 52 0,000 0,16039853 0,17470297 ! covalent chromatin modification GO:0016569 101 52 0,000 0,16039853 0,17462392 ! amino acid activation GO:0043038 92 52 0,000 0,16039853 0,17454494 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,16321908 0,17753395 ! RNA catabolic process GO:0006401 93 53 0,000 0,16321908 0,17745373 ! regulation of translational initiation GO:0006446 82 53 0,000 0,16321908 0,17737358 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,16321908 0,1772935 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,16321908 0,1772135 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,16321908 0,17713356 ! cell maturation GO:0048469 100 53 0,000 0,16321908 0,1770537 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,16321908 0,17697391 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,16321908 0,17689419 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,16603025 0,17985987 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,16603025 0,17977892 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,16603025 0,17969805 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,16603025 0,17961725 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,16603025 0,17953653 ! chloride transport GO:0006821 90 55 0,000 0,16883206 0,18248425 ! glucose catabolic process GO:0006007 82 55 0,000 0,16883206 0,18240231 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,16883206 0,18232044 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16883206 0,18223864 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,16883206 0,18215692 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,16883206 0,18207527 ! aging GO:0007568 103 55 0,000 0,16883206 0,1819937 ! gastrulation GO:0007369 112 55 0,000 0,16883206 0,1819122 ! heart morphogenesis GO:0003007 97 55 0,000 0,16883206 0,18183077 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,16883206 0,18174941 ! RNA elongation GO:0006354 79 55 0,000 0,16883206 0,18166813 ! nuclear export GO:0051168 97 55 0,000 0,16883206 0,18158692 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,16883206 0,18150578 ! regulation of actin filament length GO:0030832 105 56 0,000 0,17162455 0,18442549 ! sensory perception of smell GO:0007608 80 56 0,000 0,17162455 0,18434316 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,17162455 0,1842609 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,17162455 0,18417871 ! regulation of DNA replication GO:0006275 101 56 0,000 0,17162455 0,1840966 ! proton transport GO:0015992 94 56 0,000 0,17162455 0,18401456 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,17162455 0,1839326 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,17440776 0,18683218 ! lipid modification GO:0030258 97 57 0,000 0,17440776 0,18674903 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,17440776 0,18666596 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,17440776 0,18658296 ! hydrogen transport GO:0006818 97 58 0,000 0,1771817 0,1894663 ! regulation of endocytosis GO:0030100 91 58 0,000 0,1771817 0,18938213 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,1771817 0,18929804 ! regulation of cellular component size GO:0032535 109 59 0,000 0,17994642 0,19216649 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17994642 0,19208123 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,17994642 0,19199605 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,17994642 0,19191095 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,18270194 0,19476335 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,18270194 0,19467709 ! camera-type eye development GO:0043010 116 60 0,000 0,18270194 0,19459091 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,18270194 0,19450481 ! kidney development GO:0001822 122 60 0,000 0,18270194 0,19441878 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,18544829 0,19725402 ! mesoderm development GO:0007498 119 61 0,000 0,18544829 0,19716686 ! tRNA processing GO:0008033 89 61 0,000 0,18544829 0,19707977 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,18544829 0,19699276 ! viral reproductive process GO:0022415 126 62 0,000 0,18818551 0,19981215 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,18818551 0,19972401 ! gonad development GO:0008406 98 62 0,000 0,18818551 0,19963595 ! regulation of mitosis GO:0007088 105 63 0,000 0,19091362 0,20244079 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,19091362 0,20235161 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,19091362 0,20226251 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,19363265 0,20505288 ! cell redox homeostasis GO:0045454 102 64 0,000 0,19363265 0,20496267 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,19363265 0,20487254 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,19363265 0,20478248 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,19363265 0,20469251 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,19363265 0,20460261 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,19634263 0,20737505 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,19634263 0,20728406 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,19634263 0,20719314 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,19634263 0,20710231 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,19634263 0,20701155 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,19904359 0,20976736 ! extracellular matrix organization GO:0030198 133 66 0,000 0,19904359 0,20967552 ! secondary metabolic process GO:0019748 116 66 0,000 0,19904359 0,20958376 ! cell projection assembly GO:0030031 120 66 0,000 0,19904359 0,20949208 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,20173557 0,21223252 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,20173557 0,21213976 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,20173557 0,21204709 ! activation of MAPK activity GO:0000187 115 67 0,000 0,20173557 0,21195449 ! lung development GO:0030324 144 67 0,000 0,20173557 0,21186197 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,20173557 0,21176954 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,20173557 0,21167718 ! hexose catabolic process GO:0019320 104 67 0,000 0,20173557 0,21158491 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,20173557 0,21149272 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,20173557 0,2114006 ! adaptive immune response GO:0002250 119 67 0,000 0,20173557 0,21130857 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,20173557 0,21121662 ! amino acid transport GO:0006865 125 68 0,000 0,20441859 0,21393263 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,20441859 0,21383962 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,20441859 0,21374669 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,20441859 0,21365383 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,20441859 0,21356106 ! regulation of lipase activity GO:0060191 130 68 0,000 0,20441859 0,21346837 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,20441859 0,21337576 ! negative regulation of cell size GO:0045792 134 69 0,000 0,20709268 0,21607328 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,20709268 0,21597962 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,20709268 0,21588604 ! urogenital system development GO:0001655 137 69 0,000 0,20709268 0,21579254 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,20709268 0,21569913 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,20709268 0,21560579 ! antigen processing and presentation GO:0019882 104 69 0,000 0,20709268 0,21551254 ! respiratory tube development GO:0030323 150 70 0,000 0,20975787 0,21819171 ! amine catabolic process GO:0009310 117 71 0,000 0,21241419 0,22085935 ! reproductive structure development GO:0048608 113 71 0,000 0,21241419 0,22076395 ! humoral immune response GO:0006959 109 71 0,000 0,21241419 0,22066863 ! B cell activation GO:0042113 160 71 0,000 0,21241419 0,22057339 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,21241419 0,22047823 ! regulation of immune effector process GO:0002697 137 71 0,000 0,21241419 0,22038316 ! acute inflammatory response GO:0002526 113 72 0,000 0,21506167 0,22303378 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,21506167 0,22293769 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,21506167 0,22284168 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,21506167 0,22274575 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,21506167 0,2226499 ! respiratory system development GO:0060541 153 72 0,000 0,21506167 0,22255414 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,21770034 0,22518788 ! fertilization GO:0009566 90 73 0,000 0,21770034 0,22509111 ! neurotransmitter transport GO:0006836 123 74 0,000 0,22033022 0,22771242 ! exocytosis GO:0006887 133 74 0,000 0,22033022 0,22761465 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,22033022 0,22751696 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,22033022 0,22741935 ! eye development GO:0001654 143 74 0,000 0,22033022 0,22732183 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,22295135 0,22992754 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,22295135 0,22982903 ! rhythmic process GO:0048511 128 75 0,000 0,22295135 0,2297306 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,22556376 0,23232295 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,22556376 0,23222354 ! defense response to bacterium GO:0042742 89 76 0,000 0,22556376 0,23212421 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,22556376 0,23202497 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,22556376 0,23192581 ! regulation of catabolic process GO:0009894 161 76 0,000 0,22556376 0,23182674 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,22816747 0,23440262 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,22816747 0,23430257 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,22816747 0,23420262 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,22816747 0,23410274 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,23076251 0,23666437 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,23334892 0,23921495 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,23334892 0,23911307 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,23334892 0,23901128 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,23334892 0,23890957 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,23334892 0,23880795 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,23592671 0,24134339 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,23592671 0,24124083 ! inorganic anion transport GO:0015698 138 80 0,000 0,23592671 0,24113834 ! response to hypoxia GO:0001666 171 81 0,000 0,23849592 0,2436608 ! digestion GO:0007586 112 81 0,000 0,23849592 0,24355738 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,23849592 0,24345405 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,23849592 0,2433508 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,24105658 0,24585932 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,24105658 0,24575514 ! response to drug GO:0042493 143 82 0,000 0,24105658 0,24565105 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,24105658 0,24554705 ! response to oxygen levels GO:0070482 176 83 0,000 0,24360871 0,24804171 ! regulation of lyase activity GO:0051339 160 83 0,000 0,24360871 0,24793678 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,24615234 0,25041968 ! negative regulation of transport GO:0051051 153 84 0,000 0,24615234 0,25031384 ! negative regulation of growth GO:0045926 155 84 0,000 0,24615234 0,25020809 ! regulation of ligase activity GO:0051340 142 84 0,000 0,24615234 0,25010242 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,24615234 0,24999685 ! nucleosome assembly GO:0006334 122 85 0,000 0,24868751 0,25246504 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,24868751 0,25235856 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,24868751 0,25225217 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,25121423 0,25470773 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,25121423 0,25460044 ! chromatin assembly GO:0031497 124 86 0,000 0,25121423 0,25449324 ! alcohol catabolic process GO:0046164 130 86 0,000 0,25121423 0,25438613 ! amine transport GO:0015837 155 86 0,000 0,25121423 0,25427911 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,25373254 0,25672014 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,25373254 0,25661223 ! regulation of protein transport GO:0051223 154 87 0,000 0,25373254 0,25650441 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,25624247 0,25893296 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,25624247 0,25882426 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,26123727 0,26375865 ! sex differentiation GO:0007548 145 90 0,000 0,26123727 0,26364801 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,26123727 0,26353747 ! sterol metabolic process GO:0016125 152 91 0,000 0,2637222 0,26593278 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,2637222 0,26582137 ! nucleosome organization GO:0034728 138 92 0,000 0,26619885 0,26820538 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,26619885 0,26809311 ! vitamin metabolic process GO:0006766 139 92 0,000 0,26619885 0,26798094 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,26866726 0,27035275 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,26866726 0,27023973 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,26866726 0,2701268 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,26866726 0,27001396 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,27112745 0,27237271 ! female pregnancy GO:0007565 164 94 0,000 0,27112745 0,27225903 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,27357944 0,27460664 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,27602326 0,27694411 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,27602326 0,27682866 ! positive regulation of immune response GO:0050778 156 96 0,000 0,27602326 0,27671332 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,27845894 0,27903883 ! protein ubiquitination GO:0016567 217 97 0,000 0,27845894 0,27892266 ! hormone metabolic process GO:0042445 157 97 0,000 0,27845894 0,27880658 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,28088651 0,2811202 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,28088651 0,28100331 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,283306 0,283306