pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/427-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein sumoylation GO:0016925 17 10 5,000 1,681E-13 4,108E-10 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 1,234E-10 1,508E-07 ! myoblast cell fate commitment GO:0048625 18 6 3,000 1,345E-09 1,095E-06 ! steroid hormone receptor signaling pathway GO:0030518 146 66 5,000 6,312E-08 3,855E-05 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 5,000 9,825E-08 4,8E-05 ! myoblast differentiation GO:0045445 50 17 3,000 2,078E-07 8,459E-05 ! positive regulation of protein complex assembly GO:0031334 34 18 3,000 2,665E-07 9,3E-05 ! Notch receptor processing GO:0007220 11 5 2,000 2,951E-07 9,01E-05 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 2,951E-07 8,009E-05 ! skeletal muscle fiber development GO:0048741 130 56 4,000 9,125E-07 2,229E-04 ! muscle fiber development GO:0048747 131 57 4,000 9,977E-07 2,216E-04 ! amyloid precursor protein catabolic process GO:0042987 15 7 2,000 1,028E-06 2,093E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 1,641E-06 3,084E-04 ! fat cell differentiation GO:0045444 57 28 3,000 1,741E-06 3,037E-04 ! negative regulation of transcription regulator activity GO:0090048 57 30 3,000 2,318E-06 3,776E-04 GO:0043433|negative regulation of transcription factor activity, ! amyloid precursor protein metabolic process GO:0042982 18 9 2,000 2,456E-06 3,75E-04 ! cell cycle checkpoint GO:0000075 145 71 4,000 2,997E-06 4,306E-04 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 4,802E-06 6,518E-04 ! negative regulation of DNA binding GO:0043392 67 36 3,000 4,912E-06 6,316E-04 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 5,494E-06 6,711E-04 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 6,388E-06 7,432E-04 ! negative regulation of binding GO:0051100 71 39 3,000 6,809E-06 7,562E-04 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 8,286E-06 8,801E-04 GO:0000725|recombinational repair, ! membrane protein proteolysis GO:0033619 33 13 2,000 8,286E-06 8,434E-04 GO:0006509|membrane protein ectodomain proteolysis, ! glycoprotein catabolic process GO:0006516 33 15 2,000 1,312E-05 1,282E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 1,312E-05 1,233E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 1,391E-05 1,258E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 1,613E-05 1,407E-03 GO:0060538|skeletal muscle organ development, ! positive regulation of hormone secretion GO:0046887 35 19 2,000 2,769E-05 2,333E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 3,132E-05 2,55E-03 ! pancreas development GO:0031016 40 20 2,000 3,251E-05 2,562E-03 ! estrogen receptor signaling pathway GO:0030520 45 20 2,000 3,251E-05 2,482E-03 ! regulation of protein complex assembly GO:0043254 132 63 3,000 4,655E-05 3,446E-03 ! chromosome segregation GO:0007059 127 67 3,000 5,933E-05 4,263E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 6,484E-05 4,526E-03 ! regulation of transcription factor activity GO:0051090 137 75 3,000 9,229E-05 6,263E-03 GO:0090046|regulation of transcription regulator activity, ! lymph vessel development GO:0001945 10 5 1,000 9,606E-05 6,342E-03 ! anagen GO:0042640 7 5 1,000 9,606E-05 6,175E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 9,606E-05 6,017E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 9,606E-05 5,867E-03 ! G2/M transition checkpoint GO:0031576 8 5 1,000 9,606E-05 5,724E-03 GO:0031572|G2/M transition DNA damage checkpoint, ! mitotic recombination GO:0006312 9 5 1,000 9,606E-05 5,587E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 9,606E-05 5,457E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 9,606E-05 5,333E-03 GO:0051930|regulation of sensory perception of pain, ! cellular iron ion homeostasis GO:0006879 57 29 2,000 1,021E-04 5,542E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 1,021E-04 5,421E-03 ! muscle cell differentiation GO:0042692 178 81 3,000 1,245E-04 6,473E-03 ! iron ion homeostasis GO:0055072 60 31 2,000 1,25E-04 6,362E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 1,438E-04 7,169E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,438E-04 7,026E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! hair follicle maturation GO:0048820 8 6 1,000 1,438E-04 6,888E-03 ! regulation of DNA binding GO:0051101 167 89 3,000 1,793E-04 8,423E-03 ! positive regulation of protein ubiquitination GO:0031398 14 7 1,000 2,009E-04 9,26E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,009E-04 9,089E-03 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 2,309E-04 0,01025587 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 2,496E-04 0,01088737 ! carbohydrate homeostasis GO:0033500 59 39 2,000 2,496E-04 0,01069636 GO:0042593|glucose homeostasis, ! regulation of protein localization GO:0032880 188 97 3,000 2,496E-04 0,0105126 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,673E-04 0,01106866 ! prostaglandin biosynthetic process GO:0001516 15 8 1,000 2,673E-04 0,01088418 GO:0046457|prostanoid biosynthetic process, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 2,673E-04 0,01070575 ! osteoblast development GO:0002076 17 8 1,000 2,673E-04 0,01053308 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 2,673E-04 0,01036588 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 2,673E-04 0,01020392 ! mast cell activation GO:0045576 14 8 1,000 2,673E-04 0,01004693 ! regulation of hormone secretion GO:0046883 69 41 2,000 2,898E-04 0,01072638 ! mesenchymal cell development GO:0014031 94 41 2,000 2,898E-04 0,01056629 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! middle ear morphogenesis GO:0042474 14 9 1,000 3,43E-04 0,01232239 ! postreplication repair GO:0006301 25 9 1,000 3,43E-04 0,0121438 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 3,43E-04 0,01197032 ! regulation of telomere maintenance GO:0032204 17 9 1,000 3,43E-04 0,01180172 ! double-strand break repair GO:0006302 85 44 2,000 3,576E-04 0,01213303 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 3,823E-04 0,01279253 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 3,823E-04 0,01261966 ! pigmentation GO:0043473 103 46 2,000 4,08E-04 0,01328991 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 1,000 4,279E-04 0,01375349 ! COPI coating of Golgi vesicle GO:0048205 23 10 1,000 4,279E-04 0,01357487 GO:0048200|Golgi transport vesicle coating, ! motor axon guidance GO:0008045 22 10 1,000 4,279E-04 0,01340083 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 1,000 5,219E-04 0,01613847 ! Golgi vesicle budding GO:0048194 26 11 1,000 5,219E-04 0,01593674 ! detection of mechanical stimulus GO:0050982 22 11 1,000 5,219E-04 0,01573999 ! apical protein localization GO:0045176 18 11 1,000 5,219E-04 0,01554804 ! sequestering of metal ion GO:0051238 15 11 1,000 5,219E-04 0,01536071 ! regulation of embryonic development GO:0045995 35 11 1,000 5,219E-04 0,01517785 ! regulation of action potential GO:0001508 102 50 2,000 5,22E-04 0,01500405 ! Notch signaling pathway GO:0007219 111 52 2,000 5,86E-04 0,01664545 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 5,86E-04 0,01645413 ! focal adhesion formation GO:0048041 37 12 1,000 6,25E-04 0,01735006 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 6,25E-04 0,01715512 GO:0042130|negative regulation of T cell proliferation, ! regulation of cell shape GO:0008360 142 54 2,000 6,547E-04 0,01777101 ! asymmetric protein localization GO:0008105 24 13 1,000 7,371E-04 0,0197882 ! regulation of DNA repair GO:0006282 23 13 1,000 7,371E-04 0,01957311 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 7,371E-04 0,01936265 ! negative regulation of lipid metabolic process GO:0045833 20 13 1,000 7,371E-04 0,01915666 ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 1,000 8,582E-04 0,02206908 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 8,582E-04 0,0218392 ! positive regulation of secretion GO:0051047 110 61 2,000 9,35E-04 0,02354812 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 9,803E-04 0,02443759 ! copper ion transport GO:0006825 22 15 1,000 9,882E-04 0,02438565 ! vesicle coating GO:0006901 38 15 1,000 9,882E-04 0,02414179 ! G1/S transition checkpoint GO:0031575 37 15 1,000 9,882E-04 0,02390276 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 1,127E-03 0,02699449 ! startle response GO:0001964 28 16 1,000 1,127E-03 0,02673241 ! pituitary gland development GO:0021983 30 16 1,000 1,127E-03 0,02647537 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 1,000 1,127E-03 0,02622322 ! DNA replication initiation GO:0006270 28 16 1,000 1,127E-03 0,02597583 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 1,127E-03 0,02573307 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell cycle process GO:0010948 35 17 1,000 1,275E-03 0,02883523 ! regulation of survival gene product expression GO:0045884 38 17 1,000 1,275E-03 0,02857068 ! regulation of striated muscle contraction GO:0006942 23 17 1,000 1,275E-03 0,02831095 ! membrane budding GO:0006900 42 17 1,000 1,275E-03 0,0280559 ! DNA unwinding during replication GO:0006268 26 17 1,000 1,275E-03 0,0278054 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 1,275E-03 0,02755933 ! protein maturation by peptide bond cleavage GO:0051605 118 70 2,000 1,393E-03 0,02986079 ! patterning of blood vessels GO:0001569 43 18 1,000 1,431E-03 0,03040298 ! centrosome cycle GO:0007098 26 18 1,000 1,431E-03 0,03014088 ! cell-substrate junction assembly GO:0007044 56 18 1,000 1,431E-03 0,02988327 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 1,596E-03 0,03304845 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 1,596E-03 0,03277074 ! neuromuscular junction development GO:0007528 43 19 1,000 1,596E-03 0,03249765 ! cellular pigmentation GO:0033059 37 19 1,000 1,596E-03 0,03222907 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 1,000 1,77E-03 0,03544423 ! response to alkaloid GO:0043279 38 20 1,000 1,77E-03 0,03515607 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,77E-03 0,03487255 ! DNA duplex unwinding GO:0032508 30 20 1,000 1,77E-03 0,03459357 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,77E-03 0,03431902 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 1,77E-03 0,03404879 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 1,77E-03 0,03378278 ! negative regulation of T cell activation GO:0050868 41 20 1,000 1,77E-03 0,0335209 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 1,952E-03 0,03668957 ! prostaglandin metabolic process GO:0006693 43 21 1,000 1,952E-03 0,0364095 GO:0006692|prostanoid metabolic process, ! diencephalon development GO:0021536 36 21 1,000 1,952E-03 0,03613367 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 1,952E-03 0,03586199 ! collagen catabolic process GO:0030574 29 21 1,000 1,952E-03 0,03559436 ! reciprocal meiotic recombination GO:0007131 44 22 1,000 2,143E-03 0,03878467 ! hindlimb morphogenesis GO:0035137 47 22 1,000 2,143E-03 0,03849949 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 2,143E-03 0,03821847 ! apoptotic nuclear changes GO:0030262 34 22 1,000 2,143E-03 0,03794152 ! regulation of DNA recombination GO:0000018 51 23 1,000 2,343E-03 0,04117209 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 2,343E-03 0,04087801 ! vesicle targeting GO:0006903 49 23 1,000 2,343E-03 0,04058809 ! response to metal ion GO:0010038 158 84 2,000 2,35E-03 0,0404293 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 2,55E-03 0,04356983 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 2,55E-03 0,04326726 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 2,55E-03 0,04296887 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 2,55E-03 0,04267456 ! platelet activation GO:0030168 41 24 1,000 2,55E-03 0,04238426 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 2,766E-03 0,04566549 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 2,766E-03 0,04535901 ! response to inorganic substance GO:0010035 173 90 2,000 2,858E-03 0,04655414 ! positive regulation of protein modification process GO:0031401 156 90 2,000 2,858E-03 0,04624583 ! gland development GO:0048732 220 91 2,000 2,949E-03 0,04740076 ! myelination GO:0042552 50 26 1,000 2,991E-03 0,04775695 ! molting cycle process GO:0022404 52 26 1,000 2,991E-03 0,04744684 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! microtubule organizing center organization GO:0031023 42 26 1,000 2,991E-03 0,04714073 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,991E-03 0,04683854 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 2,991E-03 0,04654021 ! osteoblast differentiation GO:0001649 63 26 1,000 2,991E-03 0,04624565 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,991E-03 0,0459548 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 2,991E-03 0,04566758 ! regulation of cell adhesion GO:0030155 241 92 2,000 3,042E-03 0,0461553 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 3,136E-03 0,04729267 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 3,224E-03 0,04831482 ! multicellular organismal catabolic process GO:0044243 38 27 1,000 3,224E-03 0,04802021 ! regulation of chromosome organization GO:0033044 49 27 1,000 3,224E-03 0,04772918 ! cellular response to nutrient levels GO:0031669 45 27 1,000 3,224E-03 0,04744166 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 3,224E-03 0,04715758 ! regulation of membrane potential GO:0042391 179 94 2,000 3,232E-03 0,047001 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 3,635E-03 0,05253946 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 3,714E-03 0,05336678 ! icosanoid biosynthetic process GO:0046456 60 30 1,000 3,971E-03 0,05672884 ! cell junction assembly GO:0034329 85 31 1,000 4,236E-03 0,06016616 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 4,236E-03 0,05981838 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 4,236E-03 0,0594746 ! ensheathment of neurons GO:0007272 64 31 1,000 4,236E-03 0,05913474 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 4,236E-03 0,05879875 ! collagen metabolic process GO:0032963 49 32 1,000 4,509E-03 0,06223769 ! response to mechanical stimulus GO:0009612 60 32 1,000 4,509E-03 0,06188804 ! peripheral nervous system development GO:0007422 68 32 1,000 4,509E-03 0,0615423 ! myeloid leukocyte activation GO:0002274 53 32 1,000 4,509E-03 0,0612004 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 1,000 4,79E-03 0,06465735 ! establishment of vesicle localization GO:0051650 67 33 1,000 4,79E-03 0,06430209 ! adult locomotory behavior GO:0008344 62 34 1,000 5,079E-03 0,06780973 ! DNA damage checkpoint GO:0000077 78 35 1,000 5,376E-03 0,07138341 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 5,376E-03 0,07099756 ! vesicle localization GO:0051648 70 35 1,000 5,376E-03 0,07061585 ! cell junction organization GO:0034330 96 37 1,000 5,994E-03 0,07830099 ! regulation of microtubule-based process GO:0032886 86 37 1,000 5,994E-03 0,07788449 ! negative regulation of cell activation GO:0050866 69 37 1,000 5,994E-03 0,07747241 ! meiosis I GO:0007127 74 38 1,000 6,314E-03 0,08118109 ! DNA integrity checkpoint GO:0031570 82 38 1,000 6,314E-03 0,08075606 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 6,314E-03 0,08033546 ! mammary gland development GO:0030879 93 40 1,000 6,977E-03 0,08831373 ! nucleus organization GO:0006997 73 40 1,000 6,977E-03 0,0878585 ! regulation of action potential in neuron GO:0019228 80 40 1,000 6,977E-03 0,08740794 ! Rho protein signal transduction GO:0007266 88 40 1,000 6,977E-03 0,08696199 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 7,32E-03 0,09077322 ! ear morphogenesis GO:0042471 64 42 1,000 7,67E-03 0,09463842 ! T cell differentiation GO:0030217 93 42 1,000 7,67E-03 0,09416285 ! regulation of T cell differentiation GO:0045580 78 42 1,000 7,67E-03 0,09369203 ! glucose transport GO:0015758 66 43 1,000 8,028E-03 0,09757551 ! regulation of T cell proliferation GO:0042129 80 43 1,000 8,028E-03 0,09709246 ! hexose transport GO:0008645 68 44 1,000 8,393E-03 0,10100993 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 8,393E-03 0,10051478 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 8,766E-03 0,10446489 ! developmental growth GO:0048589 88 45 1,000 8,766E-03 0,10395777 ! maintenance of location in cell GO:0051651 101 45 1,000 8,766E-03 0,10345556 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 9,146E-03 0,10742028 ! response to insulin stimulus GO:0032868 98 47 1,000 9,533E-03 0,1114318 ! positive regulation of cell cycle GO:0045787 96 48 1,000 9,927E-03 0,11548889 ! cellular component disassembly GO:0022411 89 48 1,000 9,927E-03 0,11494155 ! icosanoid metabolic process GO:0006690 92 48 1,000 9,927E-03 0,11439937 ! regulation of inflammatory response GO:0050727 84 48 1,000 9,927E-03 0,11386229 ! response to calcium ion GO:0051592 94 49 1,000 0,01032893 0,11791386 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,01032893 0,11736542 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,01032893 0,11682207 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,01032893 0,11628372 ! protein homooligomerization GO:0051260 84 49 1,000 0,01032893 0,1157503 ! endocrine system development GO:0035270 109 50 1,000 0,01073755 0,11978003 ! activation of caspase activity GO:0006919 95 50 1,000 0,01073755 0,11923557 ! regulation of ossification GO:0030278 123 50 1,000 0,01073755 0,11869604 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01073755 0,11816138 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,01115323 0,12218533 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,01115323 0,12163986 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,01157592 0,12568872 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 0,01157592 0,12513258 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,01157592 0,12458133 ! vesicle organization GO:0016050 127 53 1,000 0,01200557 0,12863864 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,01200557 0,1280769 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 1,000 0,01200557 0,12752004 ! synapse organization GO:0050808 102 53 1,000 0,01200557 0,12696801 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01244214 0,13101791 ! neuromuscular process GO:0050905 107 54 1,000 0,01244214 0,13045561 ! regulation of muscle contraction GO:0006937 94 54 1,000 0,01244214 0,1298981 ! cell recognition GO:0008037 98 55 1,000 0,01288559 0,13395527 ! response to UV GO:0009411 120 55 1,000 0,01288559 0,13338766 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,01333586 0,13746622 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,0137929 0,14158009 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,0137929 0,1409877 GO:0010952|positive regulation of peptidase activity, ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01425668 0,14512114 ! maintenance of location GO:0051235 124 58 1,000 0,01425668 0,14451898 ! establishment of organelle localization GO:0051656 122 59 1,000 0,01472715 0,14867117 ! DNA catabolic process GO:0006308 94 60 1,000 0,01520426 0,15285596 ! adult behavior GO:0030534 104 60 1,000 0,01520426 0,1522295 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,0155181 0,1547376 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,0155181 0,15410858 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,0155181 0,15348466 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0155181 0,15286577 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,0155181 0,15225185 ! neuron fate determination GO:0048664 7 5 0,000 0,0155181 0,15164284 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0155181 0,15103869 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,0155181 0,15043933 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,0155181 0,14984471 ! polyol transport GO:0015791 12 5 0,000 0,0155181 0,14925477 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0155181 0,14866946 ! response to superoxide GO:0000303 10 5 0,000 0,0155181 0,14808872 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0155181 0,1475125 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,0155181 0,14694074 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,0155181 0,1463734 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0155181 0,14581043 ! female meiosis GO:0007143 10 5 0,000 0,0155181 0,14525177 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,0155181 0,14469737 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0155181 0,14414719 ! hypothalamus development GO:0021854 9 5 0,000 0,0155181 0,14360118 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,0155181 0,14305929 ! cobalt ion transport GO:0006824 11 5 0,000 0,0155181 0,14252147 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,0155181 0,14198768 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,0155181 0,14145788 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0155181 0,14093201 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0155181 0,14041004 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,0155181 0,13989192 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,0155181 0,13937761 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0155181 0,13886707 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0155181 0,13836026 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,0155181 0,13785713 ! transposition GO:0032196 9 5 0,000 0,0155181 0,13735765 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,0155181 0,13686177 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,0155181 0,13636946 ! negative chemotaxis GO:0050919 16 5 0,000 0,0155181 0,13588069 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,0155181 0,1353954 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0155181 0,13491356 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,0155181 0,13443515 ! behavioral response to pain GO:0048266 10 5 0,000 0,0155181 0,13396011 ! clathrin coat assembly GO:0048268 15 5 0,000 0,0155181 0,13348842 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0155181 0,13302004 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,0155181 0,13255493 ! micturition GO:0060073 9 5 0,000 0,0155181 0,13209307 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0155181 0,13163441 ! copulation GO:0007620 9 5 0,000 0,0155181 0,13117893 ! glial cell fate commitment GO:0021781 14 5 0,000 0,0155181 0,13072659 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,0155181 0,13027736 ! bioluminescence GO:0008218 9 5 0,000 0,0155181 0,1298312 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0155181 0,12938809 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0155181 0,128948 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0155181 0,12851089 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,0155181 0,12807673 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0155181 0,12764549 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,0155181 0,12721715 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0155181 0,12679168 ! grooming behavior GO:0007625 6 5 0,000 0,0155181 0,12636904 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,0155181 0,12594921 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0155181 0,12553216 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,0155181 0,12511786 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0155181 0,12470629 ! response to protozoan GO:0001562 13 5 0,000 0,0155181 0,12429741 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,0155181 0,12389121 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,0155181 0,12348766 ! endochondral ossification GO:0001958 17 5 0,000 0,0155181 0,12308672 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0155181 0,12268839 ! single strand break repair GO:0000012 8 5 0,000 0,0155181 0,12229262 ! parathyroid gland development GO:0060017 14 5 0,000 0,0155181 0,12189939 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0155181 0,12150869 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0155181 0,12112048 ! cytokine secretion GO:0050663 15 5 0,000 0,0155181 0,12073475 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,0155181 0,12035146 ! ceramide catabolic process GO:0046514 7 5 0,000 0,0155181 0,11997061 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,0155181 0,11959215 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,0155181 0,11921607 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0155181 0,11884235 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0155181 0,11847097 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0155181 0,1181019 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,0155181 0,11773513 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0155181 0,11737062 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0155181 0,11700837 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,0155181 0,11664834 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0155181 0,11629053 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,0155181 0,1159349 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0155181 0,11558144 ! microvillus organization GO:0032528 8 5 0,000 0,0155181 0,11523013 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,0155181 0,11488094 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,0155181 0,11453387 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,0155181 0,11418889 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,0155181 0,11384598 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,0155181 0,11350512 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,0155181 0,1131663 ! polyol catabolic process GO:0046174 9 5 0,000 0,0155181 0,1128295 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,0155181 0,11249469 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,0155181 0,11216187 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,0155181 0,11183101 ! muscle cell migration GO:0014812 8 5 0,000 0,0155181 0,11150209 ! mitochondrial fission GO:0000266 8 5 0,000 0,0155181 0,11117511 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,0155181 0,11085003 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,0155181 0,11052685 ! mRNA transcription GO:0009299 10 5 0,000 0,0155181 0,11020556 ! nerve growth factor processing GO:0032455 9 5 0,000 0,0155181 0,10988612 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,0155181 0,10956853 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,0155181 0,10925277 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,0155181 0,10893883 ! monocyte activation GO:0042117 10 5 0,000 0,0155181 0,10862668 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0155181 0,10831632 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0155181 0,10800772 ! response to food GO:0032094 6 5 0,000 0,0155181 0,10770088 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0155181 0,10739578 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0155181 0,1070924 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,0155181 0,10679074 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0155181 0,10649076 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,0155181 0,10619247 ! forebrain neuron development GO:0021884 13 5 0,000 0,0155181 0,10589584 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0155181 0,10560087 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,0155181 0,10530753 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,0155181 0,10501582 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0155181 0,10472572 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0155181 0,10443722 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,0155181 0,10415031 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0155181 0,10386496 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,0155181 0,10358118 ! lipid glycosylation GO:0030259 7 5 0,000 0,0155181 0,10329894 ! nucleobase transport GO:0015851 6 5 0,000 0,0155181 0,10301824 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0155181 0,10273905 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,0155181 0,10246138 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,0155181 0,10218521 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,0155181 0,10191051 ! basic amino acid transport GO:0015802 12 5 0,000 0,0155181 0,1016373 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,0155181 0,10136554 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,0155181 0,10109523 ! actin nucleation GO:0045010 11 5 0,000 0,0155181 0,10082636 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0155181 0,10055892 ! depurination GO:0045007 5 5 0,000 0,0155181 0,10029289 ! depyrimidination GO:0045008 10 5 0,000 0,0155181 0,10002826 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0155181 0,09976503 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0155181 0,09950318 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,0155181 0,0992427 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,0155181 0,09898358 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,0155181 0,09872581 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0155181 0,09846938 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0155181 0,09821428 ! activated T cell proliferation GO:0050798 16 5 0,000 0,0155181 0,09796049 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0155181 0,09770802 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,0155181 0,09745684 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0155181 0,09720695 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0155181 0,09695834 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,0155181 0,096711 ! response to arsenic GO:0046685 11 5 0,000 0,0155181 0,09646491 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,0155181 0,09622008 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0155181 0,09597648 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,0155181 0,09573412 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,0155181 0,09549298 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,0155181 0,09525304 ! response to mercury ion GO:0046689 8 5 0,000 0,0155181 0,09501431 ! response to cadmium ion GO:0046686 7 5 0,000 0,0155181 0,09477678 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,0155181 0,09454043 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,0155181 0,09430525 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,0155181 0,09407124 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,0155181 0,09383839 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,0155181 0,09360669 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,0155181 0,09337614 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0155181 0,09314671 ! decidualization GO:0046697 11 5 0,000 0,0155181 0,09291841 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,0155181 0,09269123 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,0155181 0,09246515 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,0155181 0,09224017 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,0155181 0,09201629 ! embryonic cleavage GO:0040016 6 5 0,000 0,0155181 0,09179349 ! peroxisome fission GO:0016559 5 5 0,000 0,0155181 0,09157177 ! histone demethylation GO:0016577 13 5 0,000 0,0155181 0,09135111 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,0155181 0,09113152 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,0155181 0,09091298 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0155181 0,09069548 ! metaphase plate congression GO:0051310 7 5 0,000 0,0155181 0,09047902 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0155181 0,0902636 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0155181 0,0900492 ! enteric nervous system development GO:0048484 8 5 0,000 0,0155181 0,08983581 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,0155181 0,08962343 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,0155181 0,08941205 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,0155181 0,08920167 ! muscle cell proliferation GO:0033002 12 5 0,000 0,0155181 0,08899228 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0155181 0,08878387 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,0155181 0,08857643 ! B cell homeostasis GO:0001782 13 5 0,000 0,0155181 0,08836996 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,0155181 0,08816444 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0155181 0,08795989 ! metaphase GO:0051323 11 5 0,000 0,0155181 0,08775628 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,0155181 0,08755361 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,0155181 0,08735187 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0155181 0,08715106 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,0155181 0,08695117 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,0155181 0,0867522 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0155181 0,08655414 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,0155181 0,08635697 ! response to redox state GO:0051775 6 5 0,000 0,0155181 0,08616071 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,0155181 0,08596533 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,0155181 0,08577084 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0155181 0,08557723 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,0155181 0,08538448 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,0155181 0,08519261 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0155181 0,08500159 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,0155181 0,08481143 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0155181 0,08462212 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,0155181 0,08443366 ! striatum development GO:0021756 14 5 0,000 0,0155181 0,08424602 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,0155181 0,08405923 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0155181 0,08387325 ! glial cell migration GO:0008347 10 5 0,000 0,0155181 0,0836881 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0155181 0,08350377 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,0155181 0,08332024 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,0155181 0,08313752 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0155181 0,0829556 ! T cell activation during immune response GO:0002286 9 5 0,000 0,0155181 0,08277448 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0155181 0,08259414 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0155181 0,08241459 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,0155181 0,08223582 ! neuroprotection GO:0043526 8 5 0,000 0,0155181 0,08205782 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0155181 0,08188059 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0155181 0,08170412 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0155181 0,08152841 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,0155181 0,08135346 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,0155181 0,08117925 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0155181 0,08100579 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,0155181 0,08083307 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0155181 0,08066109 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,0155181 0,08048983 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,0155181 0,0803193 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,0155181 0,0801495 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0155181 0,0799804 ! spindle assembly GO:0051225 6 5 0,000 0,0155181 0,07981202 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0155181 0,07964435 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0155181 0,07947738 ! protein palmitoylation GO:0018345 12 5 0,000 0,0155181 0,07931111 ! drug metabolic process GO:0017144 7 5 0,000 0,0155181 0,07914553 ! stem cell division GO:0017145 11 5 0,000 0,0155181 0,07898065 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0155181 0,07881645 ! organ regeneration GO:0031100 7 5 0,000 0,0155181 0,07865293 ! carnitine metabolic process GO:0009437 8 5 0,000 0,0155181 0,07849009 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0155181 0,07832792 ! regulation of heart contraction GO:0008016 123 61 1,000 0,01568796 0,07902204 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,01617822 0,08132383 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,01667498 0,08364881 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,0171782 0,0859966 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,0171782 0,08582074 ! ear development GO:0043583 114 66 1,000 0,01820385 0,09075921 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,01820385 0,09057437 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01859296 0,09232235 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01859296 0,09213509 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01859296 0,09194858 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01859296 0,09176282 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01859296 0,09157782 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01859296 0,09139356 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01859296 0,09121003 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01859296 0,09102725 ! response to oxygen radical GO:0000305 11 6 0,000 0,01859296 0,09084519 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01859296 0,09066387 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01859296 0,09048326 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01859296 0,09030337 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01859296 0,0901242 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01859296 0,08994574 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01859296 0,08976798 ! forebrain regionalization GO:0021871 9 6 0,000 0,01859296 0,08959092 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01859296 0,08941456 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01859296 0,08923889 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01859296 0,08906392 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01859296 0,08888962 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01859296 0,08871601 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01859296 0,08854307 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01859296 0,08837081 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01859296 0,08819922 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01859296 0,08802829 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01859296 0,08785802 ! malate metabolic process GO:0006108 13 6 0,000 0,01859296 0,08768841 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01859296 0,08751945 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01859296 0,08735115 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01859296 0,08718349 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01859296 0,08701647 ! protein refolding GO:0042026 15 6 0,000 0,01859296 0,08685009 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01859296 0,08668435 ! opsonization GO:0008228 8 6 0,000 0,01859296 0,08651923 ! mating behavior GO:0007617 7 6 0,000 0,01859296 0,08635475 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01859296 0,08619089 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01859296 0,08602765 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01859296 0,08586502 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01859296 0,08570301 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01859296 0,08554161 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01859296 0,08538082 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01859296 0,08522063 ! toxin metabolic process GO:0009404 11 6 0,000 0,01859296 0,08506104 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01859296 0,08490205 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01859296 0,08474365 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01859296 0,08458584 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01859296 0,08442862 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01859296 0,08427198 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01859296 0,08411592 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01859296 0,08396044 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01859296 0,08380553 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01859296 0,08365119 ! thymic T cell selection GO:0045061 16 6 0,000 0,01859296 0,08349742 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01859296 0,08334421 ! protein lipoylation GO:0009249 10 6 0,000 0,01859296 0,08319157 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01859296 0,08303948 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01859296 0,08288795 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01859296 0,08273697 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01859296 0,08258654 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01859296 0,08243666 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01859296 0,08228731 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01859296 0,08213851 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01859296 0,08199025 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01859296 0,08184252 ! hyperosmotic response GO:0006972 10 6 0,000 0,01859296 0,08169532 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01859296 0,08154865 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01859296 0,0814025 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01859296 0,08125688 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01859296 0,08111178 ! urea metabolic process GO:0019627 7 6 0,000 0,01859296 0,0809672 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01859296 0,08082313 ! neutrophil activation GO:0042119 7 6 0,000 0,01859296 0,08067957 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01859296 0,08053652 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01859296 0,08039398 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01859296 0,08025194 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01859296 0,0801104 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01859296 0,07996936 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01859296 0,07982882 ! neuron apoptosis GO:0051402 15 6 0,000 0,01859296 0,07968877 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01859296 0,07954921 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01859296 0,07941013 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01859296 0,07927155 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01859296 0,07913344 ! carnitine transport GO:0015879 10 6 0,000 0,01859296 0,07899582 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01859296 0,07885868 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01859296 0,07872201 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01859296 0,07858581 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01859296 0,07845008 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01859296 0,07831482 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01859296 0,07818003 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01859296 0,0780457 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01859296 0,07791183 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01859296 0,07777842 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01859296 0,07764547 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01859296 0,07751296 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01859296 0,07738091 ! response to UV-C GO:0010225 14 6 0,000 0,01859296 0,07724931 ! astrocyte development GO:0014002 16 6 0,000 0,01859296 0,07711816 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01859296 0,07698745 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01859296 0,07685719 ! interaction with symbiont GO:0051702 14 6 0,000 0,01859296 0,07672736 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01859296 0,07659797 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01859296 0,07646902 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01859296 0,0763405 ! response to copper ion GO:0046688 10 6 0,000 0,01859296 0,07621241 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01859296 0,07608475 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01859296 0,07595752 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01859296 0,07583071 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01859296 0,07570433 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01859296 0,07557836 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01859296 0,07545282 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01859296 0,07532769 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01859296 0,07520298 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01859296 0,07507867 ! Schwann cell development GO:0014044 15 6 0,000 0,01859296 0,07495478 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01859296 0,0748313 ! response to pheromone GO:0019236 6 6 0,000 0,01859296 0,07470822 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01859296 0,07458555 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01859296 0,07446327 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01859296 0,0743414 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01859296 0,07421993 ! subpallium development GO:0021544 15 6 0,000 0,01859296 0,07409885 ! neural tube patterning GO:0021532 8 6 0,000 0,01859296 0,07397817 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01859296 0,07385788 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01859296 0,07373798 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01859296 0,07361847 ! G2 phase GO:0051319 16 6 0,000 0,01859296 0,07349935 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01859296 0,07338061 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01859296 0,07326225 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01859296 0,07314428 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01859296 0,07302668 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01859296 0,07290947 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01859296 0,07279262 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01859296 0,07267616 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01859296 0,07256006 ! receptor internalization GO:0031623 11 6 0,000 0,01859296 0,07244433 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01859296 0,07232898 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01859296 0,07221399 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01859296 0,07209936 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01859296 0,0719851 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01859296 0,0718712 ! protein deubiquitination GO:0016579 16 6 0,000 0,01859296 0,07175766 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01859296 0,07164447 ! protein destabilization GO:0031648 9 6 0,000 0,01859296 0,07153165 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01859296 0,07141918 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01859296 0,07130706 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01859296 0,07119529 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01859296 0,07108388 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01859296 0,07097281 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01859296 0,07086209 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01859296 0,07075171 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01859296 0,07064168 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01859296 0,07053198 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01859296 0,07042263 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01859296 0,07031362 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01859296 0,07020494 ! neural plate development GO:0001840 9 6 0,000 0,01859296 0,0700966 ! catecholamine transport GO:0051937 9 6 0,000 0,01859296 0,06998859 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01859296 0,06988092 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01859296 0,06977357 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01859296 0,06966656 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01859296 0,06955987 ! maternal placenta development GO:0001893 12 6 0,000 0,01859296 0,06945351 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01859296 0,06934748 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01859296 0,06924176 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01859296 0,06913637 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01859296 0,0690313 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01859296 0,06892655 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01859296 0,06882212 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01859296 0,068718 GO:0055081|anion homeostasis, ! fatty acid biosynthetic process GO:0006633 139 67 1,000 0,0187262 0,06910588 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,01925482 0,07094952 ! detection of external stimulus GO:0009581 102 68 1,000 0,01925482 0,07084267 ! developmental maturation GO:0021700 128 69 1,000 0,01978969 0,07270108 ! appendage morphogenesis GO:0035107 150 72 1,000 0,02143131 0,07861366 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,02143131 0,0784958 ! actin filament organization GO:0007015 167 72 1,000 0,02143131 0,07837829 ! tRNA transcription GO:0009304 17 7 0,000 0,0216583 0,07909003 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,0216583 0,07897199 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0216583 0,07885429 ! regulation of helicase activity GO:0051095 16 7 0,000 0,0216583 0,07873695 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,0216583 0,07861996 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,0216583 0,07850331 ! sleep GO:0030431 16 7 0,000 0,0216583 0,07838701 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0216583 0,07827105 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,0216583 0,07815544 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0216583 0,07804016 ! prostate gland development GO:0030850 14 7 0,000 0,0216583 0,07792523 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,0216583 0,07781063 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0216583 0,07769638 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0216583 0,07758245 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,0216583 0,07746886 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0216583 0,0773556 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,0216583 0,07724267 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,0216583 0,07713008 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0216583 0,0770178 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,0216583 0,07690586 ! glycolipid transport GO:0046836 11 7 0,000 0,0216583 0,07679424 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0216583 0,07668294 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0216583 0,07657197 ! neuron adhesion GO:0007158 14 7 0,000 0,0216583 0,07646132 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,0216583 0,07635098 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0216583 0,07624097 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0216583 0,07613127 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,0216583 0,07602188 ! mRNA stabilization GO:0048255 18 7 0,000 0,0216583 0,07591281 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,0216583 0,07580406 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,0216583 0,07569561 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,0216583 0,07558747 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,0216583 0,07547965 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,0216583 0,07537212 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0216583 0,07526491 ! lipoprotein transport GO:0042953 14 7 0,000 0,0216583 0,075158 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,0216583 0,07505139 ! rhythmic behavior GO:0007622 17 7 0,000 0,0216583 0,07494509 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,0216583 0,07483908 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,0216583 0,07473338 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,0216583 0,07462797 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,0216583 0,07452286 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0216583 0,07441805 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,0216583 0,07431353 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0216583 0,0742093 ! mechanosensory behavior GO:0007638 16 7 0,000 0,0216583 0,07410537 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,0216583 0,07400172 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,0216583 0,07389837 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,0216583 0,0737953 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,0216583 0,07369252 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0216583 0,07359003 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0216583 0,07348782 ! spinal cord patterning GO:0021511 14 7 0,000 0,0216583 0,0733859 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,0216583 0,07328425 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,0216583 0,07318289 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0216583 0,07308181 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,0216583 0,07298101 ! adrenal gland development GO:0030325 17 7 0,000 0,0216583 0,07288048 ! cysteine metabolic process GO:0006534 13 7 0,000 0,0216583 0,07278024 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,0216583 0,07268026 ! ovulation GO:0030728 10 7 0,000 0,0216583 0,07258056 ! adenohypophysis development GO:0021984 11 7 0,000 0,0216583 0,07248114 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,0216583 0,07238199 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,0216583 0,0722831 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,0216583 0,07218449 ! microtubule nucleation GO:0007020 21 7 0,000 0,0216583 0,07208615 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0216583 0,07198807 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,0216583 0,07189026 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0216583 0,07179272 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,0216583 0,07169544 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,0216583 0,07159842 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0216583 0,07150166 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,0216583 0,07140517 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,0216583 0,07130894 ! galactose metabolic process GO:0006012 13 7 0,000 0,0216583 0,07121296 ! vesicle fusion GO:0006906 20 7 0,000 0,0216583 0,07111725 ! response to dietary excess GO:0002021 8 7 0,000 0,0216583 0,07102179 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0216583 0,07092658 ! intracellular pH reduction GO:0051452 13 7 0,000 0,0216583 0,07083164 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0216583 0,07073694 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,0216583 0,0706425 ! organ growth GO:0035265 15 7 0,000 0,0216583 0,07054831 ! nucleoside transport GO:0015858 11 7 0,000 0,0216583 0,07045437 ! nucleoside salvage GO:0043174 11 7 0,000 0,0216583 0,07036068 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,0216583 0,07026724 ! male sex determination GO:0030238 15 7 0,000 0,0216583 0,07017405 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,0216583 0,0700811 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,0216583 0,0699884 ! parturition GO:0007567 16 7 0,000 0,0216583 0,06989595 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,0216583 0,06980374 ! rRNA modification GO:0000154 14 7 0,000 0,0216583 0,06971177 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,0216583 0,06962004 ! spindle checkpoint GO:0031577 16 7 0,000 0,0216583 0,06952856 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,0216583 0,06943731 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,0216583 0,06934631 ! monocyte differentiation GO:0030224 16 7 0,000 0,0216583 0,06925554 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,0216583 0,06916501 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0216583 0,06907471 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,0216583 0,06898466 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,0216583 0,06889483 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,0216583 0,06880524 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0216583 0,06871589 ! fibrinolysis GO:0042730 11 7 0,000 0,0216583 0,06862676 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,0216583 0,06853786 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,0216583 0,0684492 ! eating behavior GO:0042755 8 7 0,000 0,0216583 0,06836076 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0216583 0,06827256 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0216583 0,06818458 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,0216583 0,06809682 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,0216583 0,0680093 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0216583 0,06792199 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,0216583 0,06783491 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0216583 0,06774806 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,0216583 0,06766142 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,0216583 0,06757501 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,0216583 0,06748882 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,0216583 0,06740284 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0216583 0,06731709 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,0216583 0,06723155 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0216583 0,06714623 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0216583 0,06706113 ! histone ubiquitination GO:0016574 9 7 0,000 0,0216583 0,06697624 ! regulation of meiosis GO:0040020 12 7 0,000 0,0216583 0,06689157 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,0216583 0,06680711 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0216583 0,06672286 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,0216583 0,06663883 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0216583 0,06655501 ! membrane to membrane docking GO:0022614 14 7 0,000 0,0216583 0,0664714 ! transcription termination GO:0006353 14 7 0,000 0,0216583 0,06638799 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0216583 0,0663048 ! anaphase GO:0051322 18 7 0,000 0,0216583 0,06622182 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,0216583 0,06613904 ! axonal fasciculation GO:0007413 19 7 0,000 0,0216583 0,06605647 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,0216583 0,0659741 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,0216583 0,06589194 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,0216583 0,06580999 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,0216583 0,06572824 ! diuresis GO:0030146 12 7 0,000 0,0216583 0,06564669 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0216583 0,06556534 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0216583 0,0654842 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0216583 0,06540325 ! antibiotic transport GO:0042891 9 7 0,000 0,0216583 0,06532251 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0216583 0,06524196 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,0216583 0,06516162 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,0216583 0,06508147 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,0216583 0,06500151 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,0216583 0,06492176 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,0216583 0,0648422 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,0216583 0,06476283 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0216583 0,06468366 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0216583 0,06460468 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,0216583 0,06452589 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,0216583 0,0644473 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,0216583 0,06436889 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,0216583 0,06429068 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,0216583 0,06421266 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,0216583 0,06413483 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,0216583 0,06405718 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,0216583 0,06397972 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,0216583 0,06390245 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0216583 0,06382537 ! muscle adaptation GO:0043500 13 7 0,000 0,0216583 0,06374847 ! embryonic heart tube development GO:0035050 14 7 0,000 0,0216583 0,06367176 ! retina homeostasis GO:0001895 12 7 0,000 0,0216583 0,06359523 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,0216583 0,06351889 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,0216583 0,06344272 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,0216583 0,06336674 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,0216583 0,06329095 ! appendage development GO:0048736 151 73 1,000 0,02199072 0,06418557 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 0,02255615 0,06575735 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,02255615 0,06567898 ! organelle localization GO:0051640 155 74 1,000 0,02255615 0,06560079 ! transition metal ion transport GO:0000041 143 75 1,000 0,02312756 0,06718267 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,02312756 0,06710288 ! axon guidance GO:0007411 162 75 1,000 0,02312756 0,06702328 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,02370491 0,06861505 ! learning or memory GO:0007611 161 76 1,000 0,02370491 0,06853385 ! regulation of blood pressure GO:0008217 134 76 1,000 0,02370491 0,06845284 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,02370491 0,06837203 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,02428817 0,0699717 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02471416 0,07111506 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02471416 0,0710314 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02471416 0,07094793 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02471416 0,07086465 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02471416 0,07078158 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02471416 0,0706987 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02471416 0,07061601 ! male meiosis GO:0007140 9 8 0,000 0,02471416 0,07053351 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02471416 0,07045121 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02471416 0,0703691 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02471416 0,07028718 ! meiotic prophase I GO:0007128 14 8 0,000 0,02471416 0,07020545 ! response to zinc ion GO:0010043 12 8 0,000 0,02471416 0,07012391 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02471416 0,07004256 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02471416 0,0699614 ! oligopeptide transport GO:0006857 16 8 0,000 0,02471416 0,06988042 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02471416 0,06979964 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02471416 0,06971904 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02471416 0,06963862 ! signal peptide processing GO:0006465 12 8 0,000 0,02471416 0,06955839 ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02471416 0,06947835 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02471416 0,06939849 ! succinate metabolic process GO:0006105 17 8 0,000 0,02471416 0,06931881 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02471416 0,06923932 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02471416 0,06916001 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02471416 0,06908088 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02471416 0,06900193 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02471416 0,06892316 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02471416 0,06884457 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02471416 0,06876616 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02471416 0,06868792 ! reflex GO:0060004 17 8 0,000 0,02471416 0,06860987 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02471416 0,06853199 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02471416 0,06845429 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02471416 0,06837677 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02471416 0,06829942 ! pigment granule organization GO:0048753 17 8 0,000 0,02471416 0,06822224 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02471416 0,06814524 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02471416 0,06806842 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02471416 0,06799176 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02471416 0,06791528 ! histidine catabolic process GO:0006548 10 8 0,000 0,02471416 0,06783897 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02471416 0,06776283 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02471416 0,06768687 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02471416 0,06761107 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,02471416 0,06753544 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02471416 0,06745998 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02471416 0,06738469 ! melanin metabolic process GO:0006582 17 8 0,000 0,02471416 0,06730957 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02471416 0,06723462 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02471416 0,06715983 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02471416 0,06708521 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02471416 0,06701075 ! macrophage activation GO:0042116 13 8 0,000 0,02471416 0,06693646 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02471416 0,06686233 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02471416 0,06678837 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02471416 0,06671457 ! purine salvage GO:0043101 12 8 0,000 0,02471416 0,06664093 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02471416 0,06656746 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02471416 0,06649415 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02471416 0,066421 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02471416 0,06634801 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02471416 0,06627518 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02471416 0,06620251 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02471416 0,06613 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02471416 0,06605764 ! response to UV-B GO:0010224 17 8 0,000 0,02471416 0,06598545 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02471416 0,06591341 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02471416 0,06584153 ! intermediate filament organization GO:0045109 12 8 0,000 0,02471416 0,06576981 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02471416 0,06569824 ! cellular extravasation GO:0045123 13 8 0,000 0,02471416 0,06562683 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02471416 0,06555558 ! response to antibiotic GO:0046677 11 8 0,000 0,02471416 0,06548448 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02471416 0,06541353 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02471416 0,06534273 ! DNA topological change GO:0006265 12 8 0,000 0,02471416 0,06527209 ! response to tropane GO:0014073 15 8 0,000 0,02471416 0,0652016 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,02471416 0,06513127 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02471416 0,06506108 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02471416 0,06499105 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02471416 0,06492117 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02471416 0,06485143 ! gas homeostasis GO:0033483 14 8 0,000 0,02471416 0,06478185 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02471416 0,06471242 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02471416 0,06464313 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02471416 0,064574 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02471416 0,06450501 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02471416 0,06443616 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02471416 0,06436747 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02471416 0,06429892 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02471416 0,06423052 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02471416 0,06416226 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02471416 0,06409415 ! response to tumor cell GO:0002347 16 8 0,000 0,02471416 0,06402618 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02471416 0,06395835 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,02471416 0,06389067 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02471416 0,06382314 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02471416 0,06375574 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02471416 0,06368849 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02471416 0,06362138 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02471416 0,06355441 ! hormone catabolic process GO:0042447 17 8 0,000 0,02471416 0,06348758 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02471416 0,06342089 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02471416 0,06335434 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02471416 0,06328793 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02471416 0,06322166 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02471416 0,06315553 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02471416 0,06308954 ! adult feeding behavior GO:0008343 10 8 0,000 0,02471416 0,06302368 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02471416 0,06295796 ! ATP catabolic process GO:0006200 11 8 0,000 0,02471416 0,06289238 ! blastocyst growth GO:0001832 19 8 0,000 0,02471416 0,06282694 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02471416 0,06276163 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02471416 0,06269645 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02471416 0,06263142 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02471416 0,06256651 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02471416 0,06250175 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02471416 0,06243711 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02471416 0,06237261 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02471416 0,06230824 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02471416 0,06224401 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02471416 0,0621799 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02471416 0,06211593 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02471416 0,06205209 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02471416 0,06198838 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02471416 0,06192481 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02471416 0,06186136 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02471416 0,06179804 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02471416 0,06173485 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02471416 0,06167179 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02471416 0,06160886 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02471416 0,06154606 ! blood coagulation GO:0007596 151 79 1,000 0,02547222 0,06336927 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,02547222 0,0633048 ! protein oligomerization GO:0051259 149 79 1,000 0,02547222 0,06324047 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,02607292 0,06466614 ! meiosis GO:0007126 143 81 1,000 0,02667936 0,06610313 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,02667936 0,06603615 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,0272915 0,06748292 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,0272915 0,06741469 ! protein import into nucleus GO:0006606 174 82 1,000 0,0272915 0,06734659 ! meiotic cell cycle GO:0051321 144 82 1,000 0,0272915 0,06727863 ! axon extension GO:0048675 16 9 0,000 0,02776055 0,06836596 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02776055 0,06829711 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02776055 0,0682284 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02776055 0,06815983 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02776055 0,0680914 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02776055 0,0680231 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02776055 0,06795494 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02776055 0,06788692 ! reproductive behavior GO:0019098 22 9 0,000 0,02776055 0,06781903 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02776055 0,06775128 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02776055 0,06768366 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02776055 0,06761618 ! UTP metabolic process GO:0046051 10 9 0,000 0,02776055 0,06754884 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02776055 0,06748162 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02776055 0,06741454 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02776055 0,0673476 ! artery development GO:0060840 25 9 0,000 0,02776055 0,06728079 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02776055 0,0672141 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02776055 0,06714756 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02776055 0,06708114 ! equilibrioception GO:0050957 20 9 0,000 0,02776055 0,06701485 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02776055 0,0669487 ! chemosensory behavior GO:0007635 21 9 0,000 0,02776055 0,06688267 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02776055 0,06681678 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02776055 0,06675102 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02776055 0,06668538 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02776055 0,06661987 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02776055 0,0665545 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02776055 0,06648925 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02776055 0,06642412 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02776055 0,06635913 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02776055 0,06629426 ! protein targeting to ER GO:0045047 25 9 0,000 0,02776055 0,06622952 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02776055 0,06616491 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02776055 0,06610042 ! T cell selection GO:0045058 27 9 0,000 0,02776055 0,06603606 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,02776055 0,06597182 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02776055 0,06590771 ! glycine catabolic process GO:0006546 15 9 0,000 0,02776055 0,06584372 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02776055 0,06577986 ! endosome organization GO:0007032 20 9 0,000 0,02776055 0,06571612 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02776055 0,0656525 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02776055 0,06558901 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02776055 0,06552563 ! mannose metabolic process GO:0006013 13 9 0,000 0,02776055 0,06546239 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02776055 0,06539926 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02776055 0,06533625 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02776055 0,06527337 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02776055 0,06521061 ! receptor clustering GO:0043113 20 9 0,000 0,02776055 0,06514796 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02776055 0,06508544 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02776055 0,06502304 ! retinol metabolic process GO:0042572 20 9 0,000 0,02776055 0,06496076 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02776055 0,06489859 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02776055 0,06483655 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02776055 0,06477462 ! macrophage differentiation GO:0030225 15 9 0,000 0,02776055 0,06471282 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02776055 0,06465113 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02776055 0,06458955 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02776055 0,0645281 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02776055 0,06446676 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02776055 0,06440554 ! response to amine stimulus GO:0014075 13 9 0,000 0,02776055 0,06434443 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02776055 0,06428344 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02776055 0,06422257 ! erythrocyte development GO:0048821 17 9 0,000 0,02776055 0,06416181 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02776055 0,06410116 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02776055 0,06404063 ! renal water homeostasis GO:0003091 15 9 0,000 0,02776055 0,06398022 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02776055 0,06391992 ! icosanoid secretion GO:0032309 15 9 0,000 0,02776055 0,06385973 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02776055 0,06379965 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02776055 0,06373969 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02776055 0,06367984 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02776055 0,0636201 ! sterol catabolic process GO:0016127 14 9 0,000 0,02776055 0,06356048 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02776055 0,06350097 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02776055 0,06344156 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02776055 0,06338227 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02776055 0,06332309 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02776055 0,06326402 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02776055 0,06320506 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02776055 0,06314621 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02776055 0,06308747 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02776055 0,06302884 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02776055 0,06297032 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02776055 0,0629119 ! purine base metabolic process GO:0006144 25 9 0,000 0,02776055 0,0628536 ! pigment granule transport GO:0051904 17 9 0,000 0,02776055 0,0627954 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02776055 0,06273731 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02776055 0,06267933 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02776055 0,06262145 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02776055 0,06256368 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02776055 0,06250602 ! mitochondrion localization GO:0051646 18 9 0,000 0,02776055 0,06244846 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,02790928 0,06272528 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,02790928 0,06266762 ! T cell activation GO:0042110 189 84 1,000 0,02853268 0,06400857 ! response to nutrient GO:0007584 135 84 1,000 0,02853268 0,06394985 ! hemostasis GO:0007599 165 85 1,000 0,02916165 0,06529964 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,02916165 0,06523984 ! mitochondrion organization GO:0007005 159 87 1,000 0,03043614 0,06802882 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03079752 0,06877362 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03079752 0,06871081 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03079752 0,06864812 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03079752 0,06858554 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03079752 0,06852308 ! associative learning GO:0008306 21 10 0,000 0,03079752 0,06846073 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03079752 0,06839849 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03079752 0,06833637 ! phosphate transport GO:0006817 24 10 0,000 0,03079752 0,06827435 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03079752 0,06821246 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03079752 0,06815067 ! CTP metabolic process GO:0046036 11 10 0,000 0,03079752 0,06808899 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03079752 0,06802743 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03079752 0,06796598 ! GTP metabolic process GO:0046039 11 10 0,000 0,03079752 0,06790464 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03079752 0,06784341 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03079752 0,06778229 ! social behavior GO:0035176 29 10 0,000 0,03079752 0,06772128 ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03079752 0,06766038 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03079752 0,06759959 ! androgen metabolic process GO:0008209 17 10 0,000 0,03079752 0,0675389 ! phospholipid efflux GO:0033700 19 10 0,000 0,03079752 0,06747833 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03079752 0,06741787 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03079752 0,06735751 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03079752 0,06729726 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03079752 0,06723712 ! lung alveolus development GO:0048286 26 10 0,000 0,03079752 0,06717709 ! pathogenesis GO:0009405 17 10 0,000 0,03079752 0,06711716 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03079752 0,06705734 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03079752 0,06699763 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03079752 0,06693802 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03079752 0,06687852 ! endoderm development GO:0007492 18 10 0,000 0,03079752 0,06681913 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03079752 0,06675984 ! arginine catabolic process GO:0006527 17 10 0,000 0,03079752 0,06670065 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03079752 0,06664158 ! proline metabolic process GO:0006560 13 10 0,000 0,03079752 0,0665826 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03079752 0,06652373 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03079752 0,06646496 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03079752 0,0664063 ! V(D)J recombination GO:0033151 34 10 0,000 0,03079752 0,06634774 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03079752 0,06628929 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03079752 0,06623093 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03079752 0,06617268 ! B cell proliferation GO:0042100 19 10 0,000 0,03079752 0,06611453 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03079752 0,06605649 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03079752 0,06599854 ! multicellular organism growth GO:0035264 19 10 0,000 0,03079752 0,0659407 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03079752 0,06588296 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03079752 0,06582532 ! ruffle organization GO:0031529 17 10 0,000 0,03079752 0,06576778 ! epithelial cell development GO:0002064 21 10 0,000 0,03079752 0,06571034 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03079752 0,065653 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03079752 0,06559576 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03079752 0,06553862 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03079752 0,06548158 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03079752 0,06542464 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03079752 0,0653678 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,03079752 0,06531106 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03079752 0,06525441 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03079752 0,06519787 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03079752 0,06514142 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03079752 0,06508507 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03079752 0,06502881 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03079752 0,06497266 ! segment specification GO:0007379 15 10 0,000 0,03079752 0,0649166 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03079752 0,06486064 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03079752 0,06480477 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03079752 0,064749 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03079752 0,06469333 ! response to dsRNA GO:0043331 23 10 0,000 0,03079752 0,06463775 ! DNA ligation GO:0006266 18 10 0,000 0,03079752 0,06458227 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03079752 0,06452688 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03079752 0,06447158 ! melanosome localization GO:0032400 16 10 0,000 0,03079752 0,06441639 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03079752 0,06436128 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03079752 0,06430627 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03079752 0,06425136 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03079752 0,06419653 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03079752 0,06414181 ! induction of an organ GO:0001759 17 10 0,000 0,03079752 0,06408717 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03079752 0,06403263 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03079752 0,06397818 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03079752 0,06392382 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03079752 0,06386956 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03079752 0,06381538 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03079752 0,0637613 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03079752 0,06370731 ! salivary gland development GO:0007431 28 10 0,000 0,03079752 0,06365342 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03079752 0,06359961 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03079752 0,06354589 ! midbrain development GO:0030901 14 10 0,000 0,03079752 0,06349227 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03079752 0,06343873 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03079752 0,06338529 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03079752 0,06333194 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03079752 0,06327867 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03079752 0,06322549 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03079752 0,06317241 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03079752 0,06311941 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03079752 0,0630665 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03079752 0,06301368 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,03079752 0,06296095 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,03079752 0,06290831 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03079752 0,06285576 ! blastocyst formation GO:0001825 18 10 0,000 0,03079752 0,06280329 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03079752 0,06275091 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03079752 0,06269862 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03079752 0,06264641 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03079752 0,06259429 ! response to nicotine GO:0035094 20 10 0,000 0,03079752 0,06254226 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03079752 0,06249031 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03079752 0,06243846 ! tube morphogenesis GO:0035239 194 89 1,000 0,03173244 0,06428056 ! cellular defense response GO:0006968 123 89 1,000 0,03173244 0,0642273 ! protein localization in nucleus GO:0034504 192 89 1,000 0,03173244 0,06417413 ! regulation of neurological system process GO:0031644 175 89 1,000 0,03173244 0,06412105 ! response to unfolded protein GO:0006986 139 90 1,000 0,03238867 0,06539299 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,03238867 0,06533899 ! ossification GO:0001503 205 91 1,000 0,03305023 0,06661857 ! bone development GO:0060348 206 92 1,000 0,03371708 0,06790671 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03382508 0,0680681 ! respiratory burst GO:0045730 17 11 0,000 0,03382508 0,06801208 ! neuron fate specification GO:0048665 18 11 0,000 0,03382508 0,06795615 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03382508 0,06790031 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03382508 0,06784456 ! thyroid gland development GO:0030878 26 11 0,000 0,03382508 0,06778891 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,03382508 0,06773334 ! synapsis GO:0007129 14 11 0,000 0,03382508 0,06767787 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03382508 0,06762249 ! response to pain GO:0048265 27 11 0,000 0,03382508 0,06756719 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03382508 0,06751199 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03382508 0,06745688 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03382508 0,06740186 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,03382508 0,06734693 ! bone resorption GO:0045453 16 11 0,000 0,03382508 0,06729208 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03382508 0,06723733 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,03382508 0,06718267 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03382508 0,06712809 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03382508 0,0670736 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03382508 0,0670192 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03382508 0,06696489 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03382508 0,06691067 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03382508 0,06685654 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03382508 0,06680249 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,03382508 0,06674853 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03382508 0,06669466 ! UV protection GO:0009650 20 11 0,000 0,03382508 0,06664087 ! adult heart development GO:0007512 16 11 0,000 0,03382508 0,06658717 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03382508 0,06653356 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03382508 0,06648003 ! macroautophagy GO:0016236 19 11 0,000 0,03382508 0,06642659 ! temperature homeostasis GO:0001659 18 11 0,000 0,03382508 0,06637324 ! behavioral fear response GO:0001662 27 11 0,000 0,03382508 0,06631997 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03382508 0,06626678 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03382508 0,06621368 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03382508 0,06616067 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03382508 0,06610774 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03382508 0,0660549 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03382508 0,06600214 ! regulation of organ growth GO:0046620 14 11 0,000 0,03382508 0,06594946 ! pigment granule localization GO:0051875 20 11 0,000 0,03382508 0,06589687 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03382508 0,06584437 ! vasoconstriction GO:0042310 20 11 0,000 0,03382508 0,06579194 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03382508 0,0657396 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03382508 0,06568734 ! embryonic axis specification GO:0000578 19 11 0,000 0,03382508 0,06563517 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03382508 0,06558308 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03382508 0,06553107 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03382508 0,06547914 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03382508 0,0654273 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03382508 0,06537554 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03382508 0,06532386 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03382508 0,06527226 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03382508 0,06522074 ! prophase GO:0051324 17 11 0,000 0,03382508 0,06516931 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03382508 0,06511795 ! nucleosome positioning GO:0016584 15 11 0,000 0,03382508 0,06506668 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03382508 0,06501548 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03382508 0,06496437 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03382508 0,06491334 ! acid secretion GO:0046717 20 11 0,000 0,03382508 0,06486239 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03382508 0,06481151 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03382508 0,06476072 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03382508 0,06471001 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03382508 0,06465937 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03382508 0,06460882 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03382508 0,06455834 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03382508 0,06450795 ! cholesterol efflux GO:0033344 21 11 0,000 0,03382508 0,06445763 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03382508 0,06440739 ! oocyte development GO:0048599 20 11 0,000 0,03382508 0,06435723 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03382508 0,06430714 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03382508 0,06425714 ! embryonic gut development GO:0048566 19 11 0,000 0,03382508 0,06420721 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03382508 0,06415736 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03382508 0,06410759 ! activation of innate immune response GO:0002218 16 11 0,000 0,03382508 0,06405789 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03382508 0,06400827 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03382508 0,06395873 ! lysogeny GO:0030069 22 11 0,000 0,03382508 0,06390926 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03382508 0,06385988 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03382508 0,06381056 ! nucleus localization GO:0051647 22 11 0,000 0,03382508 0,06376133 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,03438919 0,06477471 ! regulation of defense response GO:0031347 171 95 1,000 0,03574903 0,06728419 ! response to protein stimulus GO:0051789 158 96 1,000 0,03643667 0,06852563 ! regulation of T cell activation GO:0050863 175 96 1,000 0,03643667 0,06847291 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03684328 0,0691838 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03684328 0,06913066 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,03684328 0,06907761 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03684328 0,06902463 ! virus-host interaction GO:0019048 30 12 0,000 0,03684328 0,06897174 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,03684328 0,06891893 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,03684328 0,0688662 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03684328 0,06881355 ! protein complex disassembly GO:0043241 28 12 0,000 0,03684328 0,06876098 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03684328 0,06870849 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,03684328 0,06865608 ! hippocampus development GO:0021766 29 12 0,000 0,03684328 0,06860375 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,03684328 0,0685515 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03684328 0,06849933 ! T cell proliferation GO:0042098 32 12 0,000 0,03684328 0,06844724 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03684328 0,06839523 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03684328 0,0683433 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03684328 0,06829144 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03684328 0,06823967 ! drug transport GO:0015893 16 12 0,000 0,03684328 0,06818797 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03684328 0,06813635 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03684328 0,06808481 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03684328 0,06803335 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03684328 0,06798197 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03684328 0,06793066 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03684328 0,06787943 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03684328 0,06782828 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03684328 0,0677772 ! lipid digestion GO:0044241 21 12 0,000 0,03684328 0,0677262 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03684328 0,06767528 ! entry into host cell GO:0030260 34 12 0,000 0,03684328 0,06762443 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03684328 0,06757366 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03684328 0,06752297 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03684328 0,06747236 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03684328 0,06742181 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03684328 0,06737135 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03684328 0,06732096 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03684328 0,06727064 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03684328 0,0672204 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03684328 0,06717024 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03684328 0,06712015 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03684328 0,06707014 ! cranial nerve development GO:0021545 23 12 0,000 0,03684328 0,06702019 ! fucose catabolic process GO:0019317 25 12 0,000 0,03684328 0,06697033 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03684328 0,06692054 ! histone acetylation GO:0016573 27 12 0,000 0,03684328 0,06687082 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03684328 0,06682117 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03684328 0,0667716 ! zymogen activation GO:0031638 18 12 0,000 0,03684328 0,06672211 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03684328 0,06667268 ! T cell homeostasis GO:0043029 28 12 0,000 0,03684328 0,06662333 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03684328 0,06657405 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03684328 0,06652485 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,03684328 0,06647572 ! oocyte differentiation GO:0009994 21 12 0,000 0,03684328 0,06642666 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03684328 0,06637767 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03684328 0,06632876 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,03684328 0,06627991 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03684328 0,06623114 ! defense response to fungus GO:0050832 15 12 0,000 0,03684328 0,06618244 ! developmental induction GO:0031128 22 12 0,000 0,03684328 0,06613381 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,03684328 0,06608526 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03684328 0,06603677 ! response to cold GO:0009409 17 12 0,000 0,03684328 0,06598836 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03684328 0,06594002 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03684328 0,06589174 ! localization within membrane GO:0051668 26 12 0,000 0,03684328 0,06584354 ! transcription initiation GO:0006352 171 97 1,000 0,03712942 0,06630641 ! leukocyte differentiation GO:0002521 232 98 1,000 0,03782723 0,06750323 ! forebrain development GO:0030900 210 98 1,000 0,03782723 0,06745395 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03985212 0,07101294 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03985212 0,07096118 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03985212 0,0709095 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03985212 0,07085789 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03985212 0,07080635 ! peroxisomal transport GO:0043574 28 13 0,000 0,03985212 0,0707549 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03985212 0,07070351 ! cartilage condensation GO:0001502 22 13 0,000 0,03985212 0,0706522 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03985212 0,07060097 ! organelle fusion GO:0048284 36 13 0,000 0,03985212 0,07054981 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03985212 0,07049872 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03985212 0,07044771 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03985212 0,07039677 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03985212 0,07034591 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03985212 0,07029512 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03985212 0,0702444 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03985212 0,07019375 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03985212 0,07014318 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03985212 0,07009268 ! methionine metabolic process GO:0006555 31 13 0,000 0,03985212 0,07004226 ! plasma membrane organization GO:0007009 27 13 0,000 0,03985212 0,0699919 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03985212 0,06994162 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03985212 0,06989141 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03985212 0,06984128 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03985212 0,06979121 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03985212 0,06974122 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03985212 0,06969129 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,03985212 0,06964144 ! exocrine system development GO:0035272 34 13 0,000 0,03985212 0,06959166 ! monoamine transport GO:0015844 21 13 0,000 0,03985212 0,06954196 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,03985212 0,06949232 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,03985212 0,06944275 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03985212 0,06939326 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03985212 0,06934383 ! protein homotetramerization GO:0051289 24 13 0,000 0,03985212 0,06929448 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03985212 0,06924519 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03985212 0,06919598 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03985212 0,06914683 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03985212 0,06909776 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03985212 0,06904875 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,03985212 0,06899981 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03985212 0,06895095 ! histone methylation GO:0016571 29 13 0,000 0,03985212 0,06890215 ! chromatin silencing GO:0006342 29 13 0,000 0,03985212 0,06885342 ! gland morphogenesis GO:0022612 31 13 0,000 0,03985212 0,06880476 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03985212 0,06875617 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03985212 0,06870765 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03985212 0,06865919 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03985212 0,06861081 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03985212 0,06856249 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03985212 0,06851424 ! spleen development GO:0048536 24 13 0,000 0,03985212 0,06846606 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03985212 0,06841795 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03985212 0,0683699 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03985212 0,06832192 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03985212 0,06827401 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03985212 0,06822617 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03985212 0,06817839 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03985212 0,06813068 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03985212 0,06808303 ! insulin secretion GO:0030073 24 13 0,000 0,03985212 0,06803546 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03985212 0,06798795 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03985212 0,0679405 ! acrosome reaction GO:0007340 19 13 0,000 0,03985212 0,06789312 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03985212 0,06784581 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03985212 0,06779856 ! rRNA transcription GO:0009303 28 14 0,000 0,04285166 0,0728508 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04285166 0,07280014 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04285166 0,07274955 ! water transport GO:0006833 21 14 0,000 0,04285166 0,07269903 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04285166 0,07264858 ! non-recombinational repair GO:0000726 29 14 0,000 0,04285166 0,0725982 GO:0006303|double-strand break repair via nonhomologous end joining, ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04285166 0,07254788 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04285166 0,07249764 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04285166 0,07244747 ! lipid localization GO:0010876 32 14 0,000 0,04285166 0,07239737 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04285166 0,07234734 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04285166 0,07229737 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04285166 0,07224748 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04285166 0,07219765 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04285166 0,0721479 ! arginine metabolic process GO:0006525 21 14 0,000 0,04285166 0,07209821 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04285166 0,07204859 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,04285166 0,07199904 ! regulation of heart rate GO:0002027 25 14 0,000 0,04285166 0,07194955 ! fear response GO:0042596 34 14 0,000 0,04285166 0,07190014 ! organic alcohol transport GO:0015850 29 14 0,000 0,04285166 0,07185079 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04285166 0,07180151 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,04285166 0,07175229 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04285166 0,07170315 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04285166 0,07165407 ! bone mineralization GO:0030282 18 14 0,000 0,04285166 0,07160506 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04285166 0,07155612 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04285166 0,07150724 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04285166 0,07145843 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04285166 0,07140968 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04285166 0,07136101 ! regulation of cellular pH GO:0030641 27 14 0,000 0,04285166 0,0713124 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04285166 0,07126385 ! ribosome assembly GO:0042255 18 14 0,000 0,04285166 0,07121537 ! cerebellum development GO:0021549 23 14 0,000 0,04285166 0,07116696 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04285166 0,07111861 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04285166 0,07107033 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04285166 0,07102212 ! response to gamma radiation GO:0010332 30 14 0,000 0,04285166 0,07097396 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04285166 0,07092588 ! NADP metabolic process GO:0006739 24 14 0,000 0,04285166 0,07087786 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04285166 0,0708299 ! oxygen transport GO:0015671 22 14 0,000 0,04285166 0,07078201 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04285166 0,07073419 ! male genitalia development GO:0030539 26 14 0,000 0,04285166 0,07068643 ! regulation of RNA stability GO:0043487 33 14 0,000 0,04285166 0,07063873 ! regulation of axon extension GO:0030516 43 14 0,000 0,04285166 0,0705911 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04285166 0,07054353 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,04285166 0,07049603 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0458419 0,07536458 ! lactation GO:0007595 30 15 0,000 0,0458419 0,0753139 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,0458419 0,07526329 ! reproductive cellular process GO:0048610 22 15 0,000 0,0458419 0,07521274 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0458419 0,07516226 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0458419 0,07511185 ! superoxide anion generation GO:0042554 22 15 0,000 0,0458419 0,07506151 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0458419 0,07501123 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,0458419 0,07496102 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0458419 0,07491088 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0458419 0,07486081 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0458419 0,0748108 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0458419 0,07476086 ! sulfate transport GO:0008272 27 15 0,000 0,0458419 0,07471099 ! response to cAMP GO:0051591 25 15 0,000 0,0458419 0,07466118 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0458419 0,07461144 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0458419 0,07456176 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0458419 0,07451216 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0458419 0,07446261 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0458419 0,07441314 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0458419 0,07436373 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,0458419 0,07431438 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0458419 0,0742651 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0458419 0,07421588 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0458419 0,07416674 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0458419 0,07411765 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0458419 0,07406863 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0458419 0,07401968 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0458419 0,07397079 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0458419 0,07392196 ! histone deacetylation GO:0016575 24 15 0,000 0,0458419 0,0738732 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0458419 0,0738245 ! water homeostasis GO:0030104 28 15 0,000 0,0458419 0,07377587 ! cofactor transport GO:0051181 30 15 0,000 0,0458419 0,0737273 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0458419 0,0736788 ! muscle maintenance GO:0046716 26 15 0,000 0,0458419 0,07363036 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0458419 0,07358198 ! intestinal absorption GO:0050892 31 15 0,000 0,0458419 0,07353366 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0458419 0,07348541 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0458419 0,07343723 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0458419 0,0733891 ! cell killing GO:0001906 32 15 0,000 0,0458419 0,07334104 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0458419 0,07329304 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0458419 0,07324511 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0458419 0,07319724 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0458419 0,07314943 ! actin filament polymerization GO:0030041 27 15 0,000 0,0458419 0,07310168 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0458419 0,07305399 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04882289 0,0777538 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04882289 0,07770314 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04882289 0,07765256 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04882289 0,07760203 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04882289 0,07755158 ! bone remodeling GO:0046849 28 16 0,000 0,04882289 0,07750119 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04882289 0,07745086 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04882289 0,0774006 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04882289 0,07735041 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04882289 0,07730028 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04882289 0,07725021 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04882289 0,07720021 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04882289 0,07715028 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04882289 0,0771004 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04882289 0,0770506 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04882289 0,07700086 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04882289 0,07695118 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04882289 0,07690156 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04882289 0,07685201 ! response to osmotic stress GO:0006970 27 16 0,000 0,04882289 0,07680253 ! lysosomal transport GO:0007041 31 16 0,000 0,04882289 0,07675311 ! fructose metabolic process GO:0006000 25 16 0,000 0,04882289 0,07670375 ! L-amino acid transport GO:0015807 33 16 0,000 0,04882289 0,07665445 ! stem cell development GO:0048864 46 16 0,000 0,04882289 0,07660522 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04882289 0,07655605 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04882289 0,07650694 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04882289 0,0764579 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04882289 0,07640892 ! axon cargo transport GO:0008088 46 16 0,000 0,04882289 0,07636 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04882289 0,07631115 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04882289 0,07626236 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,04882289 0,07621363 ! neuron recognition GO:0008038 40 16 0,000 0,04882289 0,07616496 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04882289 0,07611635 ! tissue regeneration GO:0042246 27 16 0,000 0,04882289 0,07606781 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04882289 0,07601933 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04882289 0,07597091 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04882289 0,07592255 ! biomineral formation GO:0031214 22 16 0,000 0,04882289 0,07587425 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04882289 0,07582602 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04882289 0,07577784 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04882289 0,07572973 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04882289 0,07568168 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04882289 0,07563369 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04882289 0,07558576 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04882289 0,07553789 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04882289 0,07549008 ! peptide hormone processing GO:0016486 27 16 0,000 0,04882289 0,07544233 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05179465 0,07998378 ! metencephalon development GO:0022037 32 17 0,000 0,05179465 0,07993325 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,05179465 0,07988279 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,05179465 0,07983239 ! signal complex assembly GO:0007172 47 17 0,000 0,05179465 0,07978205 ! filopodium assembly GO:0046847 42 17 0,000 0,05179465 0,07973178 ! endothelial cell migration GO:0043542 31 17 0,000 0,05179465 0,07968157 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05179465 0,07963142 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05179465 0,07958134 ! glial cell development GO:0021782 28 17 0,000 0,05179465 0,07953132 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05179465 0,07948137 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05179465 0,07943147 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,05179465 0,07938164 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,05179465 0,07933187 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05179465 0,07928216 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05179465 0,07923252 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,05179465 0,07918294 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,05179465 0,07913342 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,05179465 0,07908396 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,05179465 0,07903456 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,05179465 0,07898523 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,05179465 0,07893595 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05179465 0,07888674 ! regulation of protein binding GO:0043393 33 17 0,000 0,05179465 0,07883759 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,05179465 0,0787885 ! genitalia development GO:0048806 32 17 0,000 0,05179465 0,07873947 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,05179465 0,07869051 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05179465 0,0786416 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,05179465 0,07859275 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05179465 0,07854397 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05179465 0,07849524 ! steroid catabolic process GO:0006706 34 17 0,000 0,05179465 0,07844658 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,05179465 0,07839798 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05179465 0,07834943 ! gas transport GO:0015669 26 17 0,000 0,05179465 0,07830095 ! organic cation transport GO:0015695 32 17 0,000 0,05179465 0,07825253 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,05179465 0,07820416 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05179465 0,07815586 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,05179465 0,07810761 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,05475721 0,08252428 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,05475721 0,0824734 ! limbic system development GO:0021761 40 18 0,000 0,05475721 0,08242259 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05475721 0,08237184 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,05475721 0,08232115 ! adult walking behavior GO:0007628 36 18 0,000 0,05475721 0,08227052 ! heart looping GO:0001947 34 18 0,000 0,05475721 0,08221995 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,05475721 0,08216945 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,05475721 0,08211901 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,05475721 0,08206863 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,05475721 0,08201831 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,05475721 0,08196805 ! glycine metabolic process GO:0006544 30 18 0,000 0,05475721 0,08191786 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05475721 0,08186772 ! response to retinoic acid GO:0032526 31 18 0,000 0,05475721 0,08181765 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,05475721 0,08176764 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,05475721 0,08171769 ! DNA integration GO:0015074 32 18 0,000 0,05475721 0,0816678 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,05475721 0,08161798 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,05475721 0,08156821 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,05475721 0,0815185 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,05475721 0,08146886 ! neural crest cell migration GO:0001755 41 18 0,000 0,05475721 0,08141927 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,05475721 0,08136975 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,05475721 0,08132028 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,05475721 0,08127088 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,05475721 0,08122153 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,05475721 0,08117225 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,05475721 0,08112302 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,05475721 0,08107386 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,05475721 0,08102475 ! detection of bacterium GO:0016045 22 18 0,000 0,05475721 0,0809757 ! nerve development GO:0021675 34 18 0,000 0,05475721 0,08092672 ! defense response to virus GO:0051607 43 18 0,000 0,05475721 0,08087779 ! microspike assembly GO:0030035 46 18 0,000 0,05475721 0,08082892 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,05475721 0,08078011 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,05475721 0,08073136 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05771059 0,08503437 ! positive regulation of translation GO:0045727 31 19 0,000 0,05771059 0,08498311 ! negative regulation of defense response GO:0031348 27 19 0,000 0,05771059 0,08493192 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,05771059 0,08488078 ! neuron maturation GO:0042551 46 19 0,000 0,05771059 0,08482971 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05771059 0,0847787 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05771059 0,08472775 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05771059 0,08467687 ! inositol metabolic process GO:0006020 33 19 0,000 0,05771059 0,08462604 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05771059 0,08457527 ! memory GO:0007613 34 19 0,000 0,05771059 0,08452457 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05771059 0,08447393 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05771059 0,08442334 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,05771059 0,08437282 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05771059 0,08432236 ! cerebral cortex development GO:0021987 40 19 0,000 0,05771059 0,08427196 ! pigmentation during development GO:0048066 42 19 0,000 0,05771059 0,08422161 ! response to vitamin A GO:0033189 32 19 0,000 0,05771059 0,08417133 ! heme metabolic process GO:0042168 40 19 0,000 0,05771059 0,08412111 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05771059 0,08407095 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,05771059 0,08402085 ! response to fungus GO:0009620 26 19 0,000 0,05771059 0,0839708 ! peptide cross-linking GO:0018149 39 19 0,000 0,05771059 0,08392082 ! protein export from nucleus GO:0006611 40 19 0,000 0,05771059 0,0838709 ! heart process GO:0003015 32 19 0,000 0,05771059 0,08382104 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05771059 0,08377123 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05771059 0,08372149 ! visual learning GO:0008542 38 19 0,000 0,05771059 0,0836718 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05771059 0,08362217 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05771059 0,0835726 ! vitamin transport GO:0051180 31 19 0,000 0,05771059 0,08352309 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05771059 0,08347364 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05771059 0,08342425 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05771059 0,08337492 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05771059 0,08332564 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05771059 0,08327642 ! cilium assembly GO:0042384 38 19 0,000 0,05771059 0,08322726 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05771059 0,08317816 ! protein secretion GO:0009306 45 20 0,000 0,06065483 0,08737014 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,06065483 0,08731866 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,06065483 0,08726723 ! positive regulation of ossification GO:0045778 50 20 0,000 0,06065483 0,08721587 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,06065483 0,08716456 ! skin development GO:0043588 42 20 0,000 0,06065483 0,08711332 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,06065483 0,08706214 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,06065483 0,08701102 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,06065483 0,08695995 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,06065483 0,08690895 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,06065483 0,08685801 ! response to vitamin GO:0033273 36 20 0,000 0,06065483 0,08680712 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,06065483 0,0867563 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,06065483 0,08670554 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,06065483 0,08665483 ! bile acid metabolic process GO:0008206 34 20 0,000 0,06065483 0,08660418 ! retinoid metabolic process GO:0001523 34 20 0,000 0,06065483 0,0865536 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,06065483 0,08650307 ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,06065483 0,0864526 ! body fluid secretion GO:0007589 33 20 0,000 0,06065483 0,08640219 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,06065483 0,08635184 ! peptide secretion GO:0002790 38 20 0,000 0,06065483 0,08630155 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,06065483 0,08625132 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,06065483 0,08620114 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,06065483 0,08615102 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,06065483 0,08610096 ! cell-cell junction organization GO:0045216 43 20 0,000 0,06065483 0,08605096 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,06065483 0,08600102 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,06065483 0,08595114 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,06065483 0,08590131 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,06065483 0,08585154 ! regulation of glucose import GO:0046324 30 20 0,000 0,06065483 0,08580183 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,06065483 0,08575218 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,06065483 0,08570258 ! negative regulation of translation GO:0017148 32 20 0,000 0,06065483 0,08565304 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,06065483 0,08560356 ! regulation of cell killing GO:0031341 46 21 0,000 0,06358996 0,08969415 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,06358996 0,08964239 ! hormone secretion GO:0046879 39 21 0,000 0,06358996 0,0895907 ! lipid phosphorylation GO:0046834 43 21 0,000 0,06358996 0,08953906 ! cAMP metabolic process GO:0046058 41 21 0,000 0,06358996 0,08948748 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,06358996 0,08943596 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,06358996 0,0893845 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,06358996 0,0893331 ! ovarian follicle development GO:0001541 39 21 0,000 0,06358996 0,08928176 ! smooth muscle contraction GO:0006939 48 21 0,000 0,06358996 0,08923048 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,06358996 0,08917926 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,06358996 0,08912809 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,06358996 0,08907699 ! plasma membrane fusion GO:0045026 33 21 0,000 0,06358996 0,08902594 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,06358996 0,08897495 ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,06358996 0,08892402 ! sensory perception of pain GO:0019233 33 21 0,000 0,06358996 0,08887315 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,06358996 0,08882234 ! collagen fibril organization GO:0030199 62 21 0,000 0,06358996 0,08877158 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,06358996 0,08872088 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,06358996 0,08867024 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,06358996 0,08861966 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,06358996 0,08856914 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,06358996 0,08851867 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,06358996 0,08846826 ! sperm-egg recognition GO:0035036 23 21 0,000 0,06358996 0,08841791 ! actin filament-based movement GO:0030048 47 21 0,000 0,06358996 0,08836761 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,06358996 0,08831738 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,06651599 0,09232873 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06651599 0,0922763 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06651599 0,09222393 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06651599 0,09217162 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06651599 0,09211937 ! microtubule-based transport GO:0010970 59 22 0,000 0,06651599 0,09206718 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06651599 0,09201504 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,06651599 0,09196297 ! cellular response to starvation GO:0009267 37 22 0,000 0,06651599 0,09191095 ! vacuolar transport GO:0007034 41 22 0,000 0,06651599 0,091859 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06651599 0,0918071 ! fucose metabolic process GO:0006004 44 22 0,000 0,06651599 0,09175526 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06651599 0,09170348 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06651599 0,09165176 ! ureteric bud development GO:0001657 50 22 0,000 0,06651599 0,09160009 ! cell aging GO:0007569 48 22 0,000 0,06651599 0,09154849 ! stem cell differentiation GO:0048863 57 22 0,000 0,06651599 0,09149694 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,06651599 0,09144545 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06651599 0,09139402 ! cytolysis GO:0019835 27 22 0,000 0,06651599 0,09134265 ! renal system process GO:0003014 42 22 0,000 0,06651599 0,09129133 ! vasodilation GO:0042311 40 22 0,000 0,06651599 0,09124007 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06651599 0,09118887 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,06651599 0,09113773 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,06651599 0,09108664 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06651599 0,09103561 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06651599 0,09098464 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,06651599 0,09093373 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,06651599 0,09088287 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,06651599 0,09083207 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06651599 0,09078132 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06651599 0,09073063 ! sarcomere organization GO:0045214 32 22 0,000 0,06651599 0,09068 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,06651599 0,09062943 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,06651599 0,09057891 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,06651599 0,09052845 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06651599 0,09047804 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06651599 0,09042769 ! gut development GO:0048565 44 22 0,000 0,06651599 0,0903774 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,06651599 0,09032716 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,06651599 0,09027698 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,06651599 0,09022686 ! protein stabilization GO:0050821 41 22 0,000 0,06651599 0,09017679 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,06943296 0,09407916 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06943296 0,09402701 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06943296 0,09397492 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06943296 0,09392289 ! gluconeogenesis GO:0006094 38 23 0,000 0,06943296 0,09387091 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06943296 0,09381899 ! viral genome replication GO:0019079 44 23 0,000 0,06943296 0,09376713 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06943296 0,09371532 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06943296 0,09366357 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,06943296 0,09361188 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06943296 0,09356025 ! regeneration GO:0031099 42 23 0,000 0,06943296 0,09350867 ! axis specification GO:0009798 43 23 0,000 0,06943296 0,09345715 ! visual behavior GO:0007632 46 23 0,000 0,06943296 0,09340569 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,06943296 0,09335428 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,06943296 0,09330293 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06943296 0,09325164 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06943296 0,0932004 ! peroxisome organization GO:0007031 43 23 0,000 0,06943296 0,09314922 ! lysosome organization GO:0007040 47 23 0,000 0,06943296 0,0930981 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,06943296 0,09304703 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,06943296 0,09299602 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06943296 0,09294506 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06943296 0,09289416 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06943296 0,09284331 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06943296 0,09279252 ! DNA modification GO:0006304 36 23 0,000 0,06943296 0,09274179 ! fatty acid transport GO:0015908 47 23 0,000 0,06943296 0,09269111 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06943296 0,09264049 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06943296 0,09258992 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06943296 0,09253941 ! hormone transport GO:0009914 41 23 0,000 0,06943296 0,09248895 ! cell-cell recognition GO:0009988 28 23 0,000 0,06943296 0,09243855 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06943296 0,0923882 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06943296 0,09233791 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06943296 0,09228767 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0723409 0,09610051 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0723409 0,09604828 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0723409 0,09599611 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0723409 0,09594399 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0723409 0,09589193 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0723409 0,09583993 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0723409 0,09578798 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0723409 0,09573609 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0723409 0,09568426 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0723409 0,09563248 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0723409 0,09558076 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0723409 0,0955291 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,0723409 0,09547749 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0723409 0,09542593 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0723409 0,09537444 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0723409 0,09532299 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0723409 0,09527161 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0723409 0,09522028 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0723409 0,095169 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0723409 0,09511778 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0723409 0,09506661 ! membrane depolarization GO:0051899 45 24 0,000 0,0723409 0,0950155 ! pallium development GO:0021543 56 24 0,000 0,0723409 0,09496444 ! oogenesis GO:0048477 44 24 0,000 0,0723409 0,09491344 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0723409 0,0948625 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0723409 0,0948116 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,0723409 0,09476077 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0723409 0,09470998 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0723409 0,09465926 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0723409 0,09460858 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0723409 0,09455796 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0723409 0,0945074 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0723409 0,09445688 ! regulation of amine transport GO:0051952 41 24 0,000 0,0723409 0,09440643 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,0723409 0,09435602 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,07523984 0,09808481 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,07523984 0,09803249 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,07523984 0,09798024 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,07523984 0,09792804 ! leukocyte adhesion GO:0007159 55 25 0,000 0,07523984 0,09787589 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,07523984 0,0978238 ! phototransduction GO:0007602 37 25 0,000 0,07523984 0,09777177 ! keratinization GO:0031424 37 25 0,000 0,07523984 0,09771979 ! vasculogenesis GO:0001570 49 25 0,000 0,07523984 0,09766787 ! vacuole organization GO:0007033 49 25 0,000 0,07523984 0,097616 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,07523984 0,09756419 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,07523984 0,09751243 ! receptor metabolic process GO:0043112 53 25 0,000 0,07523984 0,09746073 ! chromosome condensation GO:0030261 48 25 0,000 0,07523984 0,09740908 ! regulation of behavior GO:0050795 48 25 0,000 0,07523984 0,09735748 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,07523984 0,09730594 ! interaction with host GO:0051701 66 25 0,000 0,07523984 0,09725446 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,07523984 0,09720303 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,07523984 0,09715165 ! immunoglobulin production GO:0002377 62 25 0,000 0,07523984 0,09710033 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,07523984 0,09704906 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,07523984 0,09699785 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,07523984 0,09694669 ! liver development GO:0001889 55 25 0,000 0,07523984 0,09689559 ! protein tetramerization GO:0051262 57 25 0,000 0,07523984 0,09684454 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,0781298 0,10051137 ! initiation of viral infection GO:0019059 60 26 0,000 0,0781298 0,10045847 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,0781298 0,10040562 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,0781298 0,10035284 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,0781298 0,1003001 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,0781298 0,10024742 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,0781298 0,1001948 ! spinal cord development GO:0021510 54 26 0,000 0,0781298 0,10014223 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,0781298 0,10008972 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,0781298 0,10003726 ! digestive system process GO:0022600 49 26 0,000 0,0781298 0,09998486 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,0781298 0,09993251 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,0781298 0,09988022 ! neural crest cell development GO:0014032 59 26 0,000 0,0781298 0,09982798 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,0781298 0,09977579 ! negative regulation of cell development GO:0010721 83 26 0,000 0,0781298 0,09972366 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,0781298 0,09967159 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,0781298 0,09961957 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,0781298 0,0995676 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,0781298 0,09951569 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,0781298 0,09946383 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,0781298 0,09941203 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,0781298 0,09936028 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,0781298 0,09930858 ! blastocyst development GO:0001824 50 26 0,000 0,0781298 0,09925694 ! telomere organization GO:0032200 46 26 0,000 0,0781298 0,09920535 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,0781298 0,09915381 ! neural tube closure GO:0001843 58 26 0,000 0,0781298 0,09910233 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,0781298 0,0990509 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,0781298 0,09899953 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,0781298 0,09894821 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0810108 0,10254373 ! embryonic pattern specification GO:0009880 49 27 0,000 0,0810108 0,10249062 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,0810108 0,10243757 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,0810108 0,10238458 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,0810108 0,10233164 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,0810108 0,10227876 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,0810108 0,10222593 ! iron ion transport GO:0006826 65 27 0,000 0,0810108 0,10217315 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,0810108 0,10212043 ! superoxide metabolic process GO:0006801 41 27 0,000 0,0810108 0,10206776 ! tube lumen formation GO:0035148 59 27 0,000 0,0810108 0,10201515 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,0810108 0,10196259 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,0810108 0,10191009 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,0810108 0,10185764 ! response to starvation GO:0042594 47 27 0,000 0,0810108 0,10180524 ! response to toxin GO:0009636 49 27 0,000 0,0810108 0,1017529 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,0810108 0,10170061 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,0810108 0,10164838 ! leukocyte proliferation GO:0070661 59 27 0,000 0,0810108 0,1015962 GO:0032943|mononuclear cell proliferation, ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,08388289 0,10514412 ! neuron fate commitment GO:0048663 52 28 0,000 0,08388289 0,1050902 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,08388289 0,10503634 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,08388289 0,10498253 ! protein amino acid acylation GO:0043543 59 28 0,000 0,08388289 0,10492877 ! vesicle docking GO:0048278 55 28 0,000 0,08388289 0,10487507 ! circadian rhythm GO:0007623 56 28 0,000 0,08388289 0,10482143 ! dendrite development GO:0016358 67 28 0,000 0,08388289 0,10476784 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,08388289 0,1047143 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,08388289 0,10466082 ! sperm motility GO:0030317 37 28 0,000 0,08388289 0,1046074 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,08388289 0,10455403 ! base-excision repair GO:0006284 41 28 0,000 0,08388289 0,10450071 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,08388289 0,10444745 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,08388289 0,10439424 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,08388289 0,10434109 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,08388289 0,10428799 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,08388289 0,10423494 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,08388289 0,10418195 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,08388289 0,10412901 ! glutathione metabolic process GO:0006749 42 28 0,000 0,08388289 0,10407613 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,08388289 0,1040233 ! lipid oxidation GO:0034440 48 28 0,000 0,08388289 0,10397052 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,08388289 0,1039178 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,08388289 0,10386513 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,08674608 0,10735596 ! translational initiation GO:0006413 66 29 0,000 0,08674608 0,1073016 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,08674608 0,1072473 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,08674608 0,10719305 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,08674608 0,10713886 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,08674608 0,10708472 ! primary neural tube formation GO:0014020 61 29 0,000 0,08674608 0,10703064 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,08674608 0,10697661 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,08674608 0,10692263 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,08674608 0,10686871 ! somitogenesis GO:0001756 52 29 0,000 0,08674608 0,10681485 ! synaptogenesis GO:0007416 46 29 0,000 0,08674608 0,10676104 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,08674608 0,10670728 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,08674608 0,10665358 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,08674608 0,10659993 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,08674608 0,10654634 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0896004 0,10999687 ! phenol metabolic process GO:0018958 56 30 0,000 0,0896004 0,10994162 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,0896004 0,10988643 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0896004 0,10983129 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0896004 0,10977621 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0896004 0,10972119 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0896004 0,10966622 ! acute-phase response GO:0006953 50 30 0,000 0,0896004 0,1096113 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0896004 0,10955644 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0896004 0,10950163 ! myofibril assembly GO:0030239 50 30 0,000 0,0896004 0,10944688 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,0896004 0,10939219 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,0896004 0,10933755 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0896004 0,10928296 ! cell fate determination GO:0001709 64 30 0,000 0,0896004 0,10922843 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0896004 0,10917395 ! phospholipid transport GO:0015914 65 30 0,000 0,0896004 0,10911952 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,0896004 0,10906516 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0896004 0,10901084 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0896004 0,10895658 ! tissue homeostasis GO:0001894 50 30 0,000 0,0896004 0,10890237 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,0896004 0,10884822 ! regulation of coagulation GO:0050818 52 30 0,000 0,0896004 0,10879412 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,09244587 0,11219338 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,09244587 0,11213767 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,09244587 0,11208202 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,09244587 0,11202642 ! regulation of innate immune response GO:0045088 57 31 0,000 0,09244587 0,11197088 ! ovulation cycle process GO:0022602 55 31 0,000 0,09244587 0,1119154 ! peptide transport GO:0015833 60 31 0,000 0,09244587 0,11185997 ! male gonad development GO:0008584 56 31 0,000 0,09244587 0,11180459 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,09244587 0,11174927 ! detection of light stimulus GO:0009583 44 31 0,000 0,09244587 0,111694 ! natural killer cell activation GO:0030101 50 31 0,000 0,09244587 0,11163879 ! cofactor catabolic process GO:0051187 54 31 0,000 0,09244587 0,11158363 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,09244587 0,11152853 ! eye morphogenesis GO:0048592 65 31 0,000 0,09244587 0,11147348 ! response to heat GO:0009408 54 31 0,000 0,09244587 0,11141849 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,09244587 0,11136355 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,09528254 0,11472412 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,09528254 0,11466761 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,09528254 0,11461115 ! spindle organization GO:0007051 50 32 0,000 0,09528254 0,11455475 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,09528254 0,1144984 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,09528254 0,11444211 ! metanephros development GO:0001656 81 32 0,000 0,09528254 0,11438587 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,09528254 0,11432969 ! muscle cell development GO:0055001 52 32 0,000 0,09528254 0,11427356 ! mesoderm formation GO:0001707 73 32 0,000 0,09528254 0,11421749 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,09528254 0,11416147 ! ovulation cycle GO:0042698 57 32 0,000 0,09528254 0,11410551 ! BMP signaling pathway GO:0030509 71 32 0,000 0,09528254 0,11404961 ! hindbrain development GO:0030902 65 32 0,000 0,09528254 0,11399375 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,09528254 0,11393796 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,09528254 0,11388221 ! gene silencing GO:0016458 71 32 0,000 0,09528254 0,11382653 ! regulation of pH GO:0006885 56 33 0,000 0,09811042 0,11714749 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,09811042 0,11709026 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,09811042 0,11703308 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,09811042 0,11697597 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,09811042 0,1169189 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,09811042 0,1168619 ! response to ionizing radiation GO:0010212 74 33 0,000 0,09811042 0,11680495 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,09811042 0,11674805 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,09811042 0,11669121 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,09811042 0,11663443 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,09811042 0,1165777 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,09811042 0,11652103 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,09811042 0,11646441 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,10092954 0,11975273 ! glial cell differentiation GO:0010001 67 34 0,000 0,10092954 0,11969459 ! post-embryonic development GO:0009791 76 34 0,000 0,10092954 0,11963652 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,10092954 0,1195785 ! cholesterol transport GO:0030301 62 34 0,000 0,10092954 0,11952053 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,10092954 0,11946263 ! spliceosome assembly GO:0000245 75 34 0,000 0,10092954 0,11940478 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,10092954 0,11934698 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,10092954 0,11928924 ! formation of primary germ layer GO:0001704 76 34 0,000 0,10092954 0,11923156 ! cell fate specification GO:0001708 56 34 0,000 0,10092954 0,11917393 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,10092954 0,11911636 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,10092954 0,11905884 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,10092954 0,11900138 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,10373993 0,12225598 ! negative regulation of secretion GO:0051048 68 35 0,000 0,10373993 0,12219703 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,10373993 0,12213814 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,10373993 0,12207931 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,10373993 0,12202053 ! membrane docking GO:0022406 69 35 0,000 0,10373993 0,12196181 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,10373993 0,12190314 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,10373993 0,12184454 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,10373993 0,12178599 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,10373993 0,12172749 ! ceramide metabolic process GO:0006672 72 35 0,000 0,10373993 0,12166905 ! telencephalon development GO:0021537 81 35 0,000 0,10373993 0,12161067 ! sterol transport GO:0015918 63 35 0,000 0,10373993 0,12155234 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,10373993 0,12149407 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,10373993 0,12143586 ! placenta development GO:0001890 53 35 0,000 0,10373993 0,1213777 ! regulation of muscle development GO:0048634 82 36 0,000 0,10654161 0,12459605 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,10654161 0,12453643 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,10654161 0,12447687 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,10654161 0,12441737 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,10654161 0,12435793 ! positive regulation of cell development GO:0010720 85 36 0,000 0,10654161 0,12429854 ! protein targeting to membrane GO:0006612 75 36 0,000 0,10654161 0,12423921 ! regulation of proteolysis GO:0030162 77 36 0,000 0,10654161 0,12417993 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,10654161 0,12412072 ! aerobic respiration GO:0009060 56 36 0,000 0,10654161 0,12406156 ! cytokine production GO:0001816 68 36 0,000 0,10654161 0,12400245 ! embryonic organ development GO:0048568 67 36 0,000 0,10654161 0,1239434 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,10654161 0,12388441 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,10654161 0,12382547 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,10933461 0,12701115 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,10933461 0,12695078 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,10933461 0,12689047 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,10933461 0,12683022 ! sister chromatid segregation GO:0000819 65 37 0,000 0,10933461 0,12677003 ! odontogenesis GO:0042476 74 37 0,000 0,10933461 0,12670989 ! actomyosin structure organization GO:0031032 68 37 0,000 0,10933461 0,12664981 ! tissue remodeling GO:0048771 78 37 0,000 0,10933461 0,12658978 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,10933461 0,12652982 ! female gonad development GO:0008585 71 37 0,000 0,10933461 0,12646991 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,10933461 0,12641005 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,11211896 0,12956793 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,11211896 0,12950667 ! organic anion transport GO:0015711 82 38 0,000 0,11211896 0,12944547 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,11211896 0,12938432 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,11211896 0,12932323 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,11211896 0,1292622 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,11211896 0,12920123 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,11211896 0,12914031 ! regulation of protein stability GO:0031647 77 38 0,000 0,11211896 0,12907946 ! spermatid development GO:0007286 69 38 0,000 0,11211896 0,12901866 ! glycogen metabolic process GO:0005977 63 38 0,000 0,11211896 0,12895791 ! pigment metabolic process GO:0042440 87 38 0,000 0,11211896 0,12889723 ! neural tube formation GO:0001841 79 38 0,000 0,11211896 0,1288366 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,11489468 0,13196413 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,11489468 0,13190211 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,11489468 0,13184016 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,11489468 0,13177826 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,11489468 0,13171642 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,11489468 0,13165464 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,11489468 0,13159292 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,11489468 0,13153125 ! glucan metabolic process GO:0044042 64 39 0,000 0,11489468 0,13146965 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,1176618 0,13457293 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,1176618 0,13450996 ! learning GO:0007612 82 40 0,000 0,1176618 0,13444704 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,1176618 0,13438419 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,1176618 0,13432139 ! mismatch repair GO:0006298 58 40 0,000 0,1176618 0,13425865 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,1176618 0,13419597 ! RNA export from nucleus GO:0006405 61 41 0,000 0,12042035 0,13727807 ! mRNA catabolic process GO:0006402 79 41 0,000 0,12042035 0,13721405 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,12042035 0,13715008 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,12042035 0,13708617 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,12042035 0,13702232 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,12042035 0,13695853 ! gliogenesis GO:0042063 91 41 0,000 0,12042035 0,13689479 ! feeding behavior GO:0007631 69 41 0,000 0,12042035 0,13683112 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,12042035 0,13676751 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,12042035 0,13670396 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,12042035 0,13664046 ! spermatid differentiation GO:0048515 73 41 0,000 0,12042035 0,13657703 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,12042035 0,13651365 ! RNA modification GO:0009451 64 41 0,000 0,12042035 0,13645033 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,12317035 0,1395017 ! organic ether metabolic process GO:0018904 59 42 0,000 0,12317035 0,13943706 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,12317035 0,13937247 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,12317035 0,13930795 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,12317035 0,13924348 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,12317035 0,13917908 ! regulation of protein secretion GO:0050708 77 42 0,000 0,12317035 0,13911473 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,12317035 0,13905045 ! cytokinesis GO:0000910 84 42 0,000 0,12317035 0,13898622 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,12317035 0,13892205 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,12591183 0,1419486 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,12591183 0,14188312 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,12591183 0,14181771 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,12591183 0,14175236 ! regulation of tube size GO:0035150 76 43 0,000 0,12591183 0,14168706 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,12591183 0,14162183 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,12591183 0,14155665 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,12591183 0,14149154 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,12591183 0,14142649 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,12591183 0,14136149 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,12591183 0,14129656 ! segmentation GO:0035282 78 43 0,000 0,12591183 0,14123169 ! ion transmembrane transport GO:0034220 79 43 0,000 0,12591183 0,14116687 ! neuron migration GO:0001764 85 43 0,000 0,12591183 0,14110211 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,12591183 0,14103742 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,12864482 0,14403268 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,12864482 0,1439667 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,12864482 0,14390078 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,12864482 0,14383492 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,12864482 0,14376912 ! striated muscle contraction GO:0006941 85 44 0,000 0,12864482 0,14370338 ! phagocytosis GO:0006909 105 44 0,000 0,12864482 0,14363771 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,12864482 0,14357209 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,13136934 0,1465458 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,13136934 0,14647891 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,13136934 0,14641209 ! biopolymer methylation GO:0043414 91 45 0,000 0,13136934 0,14634533 ! B cell differentiation GO:0030183 124 45 0,000 0,13136934 0,14627862 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,13136934 0,14621198 ! female gamete generation GO:0007292 71 45 0,000 0,13136934 0,1461454 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,13136934 0,14607888 ! polyol metabolic process GO:0019751 77 45 0,000 0,13136934 0,14601242 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,13408542 0,14896347 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,13408542 0,14889576 ! glycolysis GO:0006096 71 46 0,000 0,13408542 0,14882811 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,13408542 0,14876052 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,13408542 0,148693 ! leukocyte migration GO:0050900 75 46 0,000 0,13408542 0,14862553 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,13408542 0,14855813 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,13408542 0,14849079 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,13408542 0,1484235 ! cell growth GO:0016049 90 46 0,000 0,13408542 0,14835628 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,13408542 0,14828912 ! neural tube development GO:0021915 91 47 0,000 0,13679308 0,15121515 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,13679308 0,15114676 ! positive regulation of defense response GO:0031349 88 48 0,000 0,13949235 0,15405959 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,13949235 0,15398997 ! mitochondrial transport GO:0006839 94 48 0,000 0,13949235 0,15392042 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,13949235 0,15385093 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,13949235 0,1537815 ! endosome transport GO:0016197 127 48 0,000 0,13949235 0,15371213 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,13949235 0,15364283 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,13949235 0,15357359 ! male sex differentiation GO:0046661 93 48 0,000 0,13949235 0,15350442 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,13949235 0,1534353 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,13949235 0,15336625 ! methylation GO:0032259 97 48 0,000 0,13949235 0,15329726 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,14218325 0,15618421 ! JNK cascade GO:0007254 106 49 0,000 0,14218325 0,15611401 ! regulation of ion transport GO:0043269 86 50 0,000 0,14486582 0,15898796 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,14486582 0,15891656 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,14486582 0,15884524 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,14486582 0,15877397 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,14486582 0,15870278 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,14486582 0,15863164 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,14486582 0,15856057 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,14754007 0,16141531 ! viral infectious cycle GO:0019058 104 51 0,000 0,14754007 0,16134306 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,14754007 0,16127087 ! peptide metabolic process GO:0006518 80 51 0,000 0,14754007 0,16119874 ! response to temperature stimulus GO:0009266 84 51 0,000 0,14754007 0,16112668 ! positive regulation of binding GO:0051099 88 52 0,000 0,15020603 0,16396485 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,15020603 0,16389162 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,15020603 0,16381845 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,15020603 0,16374535 ! excretion GO:0007588 87 52 0,000 0,15020603 0,16367232 ! histone modification GO:0016570 104 52 0,000 0,15020603 0,16359935 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,15020603 0,16352644 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,15020603 0,1634536 ! amino acid activation GO:0043038 98 52 0,000 0,15020603 0,16338083 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,15286373 0,16619764 ! positive regulation of growth GO:0045927 96 53 0,000 0,15286373 0,16612371 ! inner ear development GO:0048839 89 53 0,000 0,15286373 0,16604984 ! chromatin remodeling GO:0006338 122 53 0,000 0,15286373 0,16597604 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,15286373 0,16590231 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,15286373 0,16582864 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,15286373 0,16575504 ! regulation of translational initiation GO:0006446 87 54 0,000 0,1555132 0,16855312 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,1555132 0,16847838 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,1555132 0,1684037 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 0,000 0,1555132 0,16832908 ! membrane fusion GO:0006944 122 54 0,000 0,1555132 0,16825454 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,1555132 0,16818005 ! covalent chromatin modification GO:0016569 115 54 0,000 0,1555132 0,16810564 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,1555132 0,16803129 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,1555132 0,167957 ! RNA catabolic process GO:0006401 103 55 0,000 0,15815445 0,17073412 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,15815445 0,17065871 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,15815445 0,17058336 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,15815445 0,17050808 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,15815445 0,17043287 ! cell maturation GO:0048469 107 55 0,000 0,15815445 0,17035772 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,15815445 0,17028264 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,15815445 0,17020763 ! glucose catabolic process GO:0006007 88 56 0,000 0,16078751 0,17296517 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,16078751 0,17288904 ! regulation of DNA replication GO:0006275 105 56 0,000 0,16078751 0,17281298 ! RNA elongation GO:0006354 90 56 0,000 0,16078751 0,17273698 ! chloride transport GO:0006821 102 57 0,000 0,16341242 0,1754798 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,16341242 0,1754027 ! heart morphogenesis GO:0003007 105 57 0,000 0,16341242 0,17532566 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,16341242 0,1752487 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,16341242 0,1751718 ! regulation of actin filament length GO:0030832 118 58 0,000 0,16602919 0,17789882 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,16602919 0,17782082 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,16602919 0,1777429 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,16602919 0,17766505 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,16602919 0,17758726 ! aging GO:0007568 112 58 0,000 0,16602919 0,17750954 ! gastrulation GO:0007369 122 58 0,000 0,16602919 0,17743189 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,16602919 0,17735431 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,16602919 0,17727679 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,16602919 0,17719935 ! nuclear export GO:0051168 110 59 0,000 0,16863784 0,17990491 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,17123841 0,18259949 ! lipid modification GO:0030258 112 60 0,000 0,17123841 0,18251982 ! regulation of endocytosis GO:0030100 104 60 0,000 0,17123841 0,18244023 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,17123841 0,1823607 ! kidney development GO:0001822 133 60 0,000 0,17123841 0,18228124 ! regulation of cellular component size GO:0032535 125 61 0,000 0,17383092 0,18496034 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,17383092 0,18487981 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,17383092 0,18479936 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,17383092 0,18471898 ! camera-type eye development GO:0043010 126 61 0,000 0,17383092 0,18463867 ! proton transport GO:0015992 117 61 0,000 0,17383092 0,18455842 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,17383092 0,18447825 ! viral reproductive process GO:0022415 132 62 0,000 0,17641539 0,18713973 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,17641539 0,1870585 ! tRNA processing GO:0008033 102 62 0,000 0,17641539 0,18697735 ! regulation of mitosis GO:0007088 112 63 0,000 0,17899185 0,18962579 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,17899185 0,1895436 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,17899185 0,18946147 ! hydrogen transport GO:0006818 121 64 0,000 0,18156032 0,19209695 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,18156032 0,19201379 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,18156032 0,1919307 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,18412083 0,19455328 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,18412083 0,19446916 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,18412083 0,19438512 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,18412083 0,19430116 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,18412083 0,19421726 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,18412083 0,19413344 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,18667339 0,19673991 ! gonad development GO:0008406 115 66 0,000 0,18667339 0,19665507 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,18921805 0,19924987 ! activation of MAPK activity GO:0000187 124 67 0,000 0,18921805 0,19916402 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,18921805 0,19907825 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,18921805 0,19899255 ! secondary metabolic process GO:0019748 125 67 0,000 0,18921805 0,19890692 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,18921805 0,19882137 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,19175481 0,20140026 ! hexose catabolic process GO:0019320 113 68 0,000 0,19175481 0,20131371 ! extracellular matrix organization GO:0030198 146 68 0,000 0,19175481 0,20122724 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,19175481 0,20114084 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,19175481 0,20105451 ! viral reproduction GO:0016032 142 68 0,000 0,19175481 0,20096826 ! regulation of lipase activity GO:0060191 137 68 0,000 0,19175481 0,20088208 ! adaptive immune response GO:0002250 126 68 0,000 0,19175481 0,20079597 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,19175481 0,20070994 ! cell projection assembly GO:0030031 138 68 0,000 0,19175481 0,20062399 ! negative regulation of cell size GO:0045792 144 69 0,000 0,19428371 0,20318284 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,19428371 0,2030959 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,19428371 0,20300903 ! lung development GO:0030324 165 69 0,000 0,19428371 0,20292224 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,19428371 0,20283552 ! urogenital system development GO:0001655 149 69 0,000 0,19428371 0,20274887 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,19428371 0,2026623 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,19428371 0,2025758 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,19428371 0,20248938 ! single fertilization GO:0007338 83 69 0,000 0,19428371 0,20240303 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,19680477 0,20494205 ! cell redox homeostasis GO:0045454 114 70 0,000 0,19680477 0,20485473 ! germ cell development GO:0007281 133 70 0,000 0,19680477 0,20476748 ! activation of immune response GO:0002253 120 70 0,000 0,19680477 0,20468031 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,19931801 0,20720591 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,19931801 0,20711778 ! respiratory tube development GO:0030323 171 72 0,000 0,20182346 0,2096321 ! B cell activation GO:0042113 179 72 0,000 0,20182346 0,20954301 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,20182346 0,20945399 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,20182346 0,20936505 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,20182346 0,20927619 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,20182346 0,2091874 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,20182346 0,20909869 ! humoral immune response GO:0006959 115 73 0,000 0,20432113 0,21159666 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,20432113 0,211507 ! regulation of immune effector process GO:0002697 156 73 0,000 0,20432113 0,21141742 ! acute inflammatory response GO:0002526 118 74 0,000 0,20681106 0,21390323 ! amino acid transport GO:0006865 148 74 0,000 0,20681106 0,21381271 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,20681106 0,21372226 ! respiratory system development GO:0060541 175 74 0,000 0,20681106 0,21363189 ! reproductive structure development GO:0048608 131 75 0,000 0,20929327 0,21610459 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,20929327 0,21601329 ! eye development GO:0001654 155 75 0,000 0,20929327 0,21592207 ! rhythmic process GO:0048511 142 75 0,000 0,20929327 0,21583093 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,21176778 0,21829059 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,21176778 0,21819852 ! amine catabolic process GO:0009310 136 77 0,000 0,21423462 0,22064721 ! neurotransmitter transport GO:0006836 142 77 0,000 0,21423462 0,22055423 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,21423462 0,22046132 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,21423462 0,2203685 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,21423462 0,22027575 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,21423462 0,22018308 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,21423462 0,22009049 ! regulation of catabolic process GO:0009894 173 77 0,000 0,21423462 0,21999797 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,21669381 0,22242982 ! antigen processing and presentation GO:0019882 117 78 0,000 0,21669381 0,2223364 ! fertilization GO:0009566 99 78 0,000 0,21669381 0,22224306 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,21669381 0,2221498 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,21914537 0,22456885 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,21914537 0,22447469 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,21914537 0,22438061 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,21914537 0,22428661 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,22158932 0,22669293 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,22158932 0,22659804 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,22158932 0,22650323 ! response to hypoxia GO:0001666 178 81 0,000 0,2240257 0,22889786 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,2240257 0,22880216 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,2288758 0,23365799 ! exocytosis GO:0006887 153 83 0,000 0,2288758 0,23356039 ! response to drug GO:0042493 149 83 0,000 0,2288758 0,23346287 ! response to oxygen levels GO:0070482 183 83 0,000 0,2288758 0,23336543 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,2288758 0,23326807 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,2288758 0,2331708 ! inorganic anion transport GO:0015698 156 83 0,000 0,2288758 0,2330736 ! digestion GO:0007586 130 84 0,000 0,23128957 0,23543351 ! regulation of ligase activity GO:0051340 147 84 0,000 0,23128957 0,23533545 ! negative regulation of transport GO:0051051 164 85 0,000 0,23369585 0,23768483 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,23369585 0,23758592 ! negative regulation of growth GO:0045926 168 85 0,000 0,23369585 0,23748709 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,23369585 0,23738835 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,23369585 0,23728968 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,23369585 0,2371911 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,23609467 0,23952628 ! regulation of lyase activity GO:0051339 169 86 0,000 0,23609467 0,23942685 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,23609467 0,23932751 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,23848605 0,24165136 ! alcohol catabolic process GO:0046164 142 87 0,000 0,23848605 0,24155117 ! nucleosome assembly GO:0006334 126 87 0,000 0,23848605 0,24145107 ! regulation of protein transport GO:0051223 165 87 0,000 0,23848605 0,24135105 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,24087001 0,24366271 ! amine biosynthetic process GO:0009309 146 88 0,000 0,24087001 0,24356185 ! sensory perception of smell GO:0007608 117 88 0,000 0,24087001 0,24346108 ! chromatin assembly GO:0031497 128 88 0,000 0,24087001 0,2433604 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,24087001 0,24325979 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,24324658 0,24555842 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,24561577 0,24784771 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,2479776 0,2501277 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,2479776 0,25002447 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,25033212 0,25229429 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,25267932 0,25455488 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,25267932 0,25444995 ! vitamin metabolic process GO:0006766 153 93 0,000 0,25267932 0,25434511 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,25501924 0,25659473 ! female pregnancy GO:0007565 166 94 0,000 0,25501924 0,2564891 ! sterol metabolic process GO:0016125 166 94 0,000 0,25501924 0,25638354 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,25501924 0,25627808 ! nucleosome organization GO:0034728 143 95 0,000 0,25735191 0,25851592 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,25735191 0,25840966 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,25735191 0,25830349 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,25735191 0,25819742 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,25735191 0,25809142 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,25735191 0,25798552 ! sex differentiation GO:0007548 171 96 0,000 0,25967733 0,26020989 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,26199554 0,26242521 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,26430655 0,26463152 ! mRNA transport GO:0051028 185 100 0,000 0,26890708 0,26912741 ! positive regulation of immune response GO:0050778 175 100 0,000 0,26890708 0,2690172 ! hormone metabolic process GO:0042445 171 100 0,000 0,26890708 0,26890708