pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/301-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 5,079E-08 1,222E-04 ! positive regulation of vasoconstriction GO:0045907 9 5 2,000 6,073E-08 7,306E-05 ! positive regulation of microtubule polymerization GO:0031116 13 6 2,000 1,213E-07 9,728E-05 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 2,12E-07 1,275E-04 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 2,000 2,12E-07 1,02E-04 ! regulation of microtubule polymerization GO:0031113 15 7 2,000 2,12E-07 8,501E-05 ! cholesterol homeostasis GO:0042632 53 31 3,000 3,249E-07 1,117E-04 GO:0055092|sterol homeostasis, ! protein oligomerization GO:0051259 139 78 4,000 3,524E-07 1,06E-04 ! cholesterol transport GO:0030301 56 32 3,000 3,707E-07 9,911E-05 ! negative regulation of MAP kinase activity GO:0043407 69 32 3,000 3,707E-07 8,92E-05 ! sterol transport GO:0015918 57 33 3,000 4,213E-07 9,215E-05 ! cholesterol metabolic process GO:0008203 136 82 4,000 4,529E-07 9,081E-05 ! regulation of epithelial cell differentiation GO:0030856 14 9 2,000 5,074E-07 9,392E-05 ! gas homeostasis GO:0033483 16 9 2,000 5,074E-07 8,721E-05 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 7,24E-07 1,161E-04 ! lipid homeostasis GO:0055088 67 38 3,000 7,547E-07 1,135E-04 ! isoprenoid metabolic process GO:0006720 66 38 3,000 7,547E-07 1,068E-04 ! sterol metabolic process GO:0016125 152 91 4,000 7,622E-07 1,019E-04 ! gland morphogenesis GO:0022612 29 12 2,000 1,324E-06 1,676E-04 ! lipid localization GO:0010876 28 13 2,000 1,719E-06 2,068E-04 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 25 13 2,000 1,719E-06 1,969E-04 ! protein homooligomerization GO:0051260 76 47 3,000 1,801E-06 1,97E-04 ! isoprenoid biosynthetic process GO:0008299 32 15 2,000 2,727E-06 2,853E-04 ! regulation of vasodilation GO:0042312 26 15 2,000 2,727E-06 2,734E-04 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 2,000 3,352E-06 3,226E-04 ! positive regulation of protein complex assembly GO:0031334 32 17 2,000 4,065E-06 3,761E-04 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 5,169E-06 4,606E-04 ! regulation of fatty acid metabolic process GO:0019217 38 20 2,000 6,788E-06 5,832E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 7,53E-06 6,247E-04 ! inactivation of MAPK activity GO:0000188 39 21 2,000 7,908E-06 6,342E-04 ! cholesterol biosynthetic process GO:0006695 37 21 2,000 7,908E-06 6,138E-04 ! regulation of vasoconstriction GO:0019229 39 21 2,000 7,908E-06 5,946E-04 ! negative regulation of kinase activity GO:0033673 131 68 3,000 7,989E-06 5,825E-04 ! positive regulation of cytoskeleton organization GO:0051495 48 22 2,000 9,145E-06 6,471E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 9,145E-06 6,286E-04 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,004E-05 6,708E-04 ! membrane depolarization GO:0051899 39 24 2,000 1,199E-05 7,795E-04 ! vasculogenesis GO:0001570 46 25 2,000 1,36E-05 8,614E-04 ! regulation of smooth muscle contraction GO:0006940 43 25 2,000 1,36E-05 8,393E-04 ! interaction with host GO:0051701 62 25 2,000 1,36E-05 8,183E-04 ! regulation of blood coagulation GO:0030193 40 25 2,000 1,36E-05 7,983E-04 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,452E-05 8,317E-04 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,536E-05 8,593E-04 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 1,536E-05 8,398E-04 ! regulation of cellular ketone metabolic process GO:0010565 44 26 2,000 1,536E-05 8,212E-04 ! complement activation, classical pathway GO:0006958 48 29 2,000 2,15E-05 1,124E-03 ! sterol biosynthetic process GO:0016126 52 29 2,000 2,15E-05 1,101E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 2,15E-05 1,078E-03 ! regulation of coagulation GO:0050818 46 29 2,000 2,15E-05 1,056E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 2,000 2,386E-05 1,148E-03 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 2,000 2,638E-05 1,244E-03 ! triglyceride metabolic process GO:0006641 43 31 2,000 2,638E-05 1,22E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,384E-05 1,536E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,384E-05 1,508E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 3,384E-05 1,48E-03 ! lipoprotein catabolic process GO:0042159 11 5 1,000 3,384E-05 1,454E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 3,498E-05 1,476E-03 ! neutral lipid metabolic process GO:0006638 50 35 2,000 3,821E-05 1,585E-03 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 2,000 3,821E-05 1,558E-03 ! tissue remodeling GO:0048771 76 37 2,000 4,524E-05 1,814E-03 ! glycerol ether metabolic process GO:0006662 53 37 2,000 4,524E-05 1,784E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 4,524E-05 1,755E-03 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 2,000 4,905E-05 1,873E-03 GO:0006956|complement activation, ! male sex determination GO:0030238 15 6 1,000 5,069E-05 1,906E-03 ! interaction with symbiont GO:0051702 13 6 1,000 5,069E-05 1,876E-03 ! mammary gland development GO:0030879 86 39 2,000 5,307E-05 1,935E-03 ! organic ether metabolic process GO:0018904 55 39 2,000 5,307E-05 1,906E-03 ! vesicle fusion GO:0006906 17 7 1,000 7,089E-05 2,508E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,089E-05 2,472E-03 ! coenzyme A metabolic process GO:0015936 12 7 1,000 7,089E-05 2,436E-03 ! receptor-mediated endocytosis GO:0006898 88 43 2,000 7,128E-05 2,416E-03 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 8,175E-05 2,732E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 8,734E-05 2,878E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 9,44E-05 3,069E-03 ! immunoglobulin mediated immune response GO:0016064 83 49 2,000 1,056E-04 3,387E-03 GO:0019724|B cell mediated immunity, ! vesicle organization GO:0016050 107 51 2,000 1,19E-04 3,768E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,212E-04 3,788E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,212E-04 3,739E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 1,212E-04 3,692E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,212E-04 3,646E-03 ! receptor clustering GO:0043113 18 9 1,000 1,212E-04 3,601E-03 ! retinol metabolic process GO:0042572 18 9 1,000 1,212E-04 3,557E-03 ! intestinal cholesterol absorption GO:0030299 16 9 1,000 1,212E-04 3,514E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,212E-04 3,472E-03 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,212E-04 3,432E-03 ! regulation of muscle contraction GO:0006937 81 52 2,000 1,261E-04 3,529E-03 ! regulation of protein polymerization GO:0032271 103 53 2,000 1,335E-04 3,693E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,514E-04 4,138E-03 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 1,000 1,514E-04 4,092E-03 ! positive regulation of organelle organization GO:0010638 100 56 2,000 1,574E-04 4,208E-03 ! lipid digestion GO:0044241 18 11 1,000 1,848E-04 4,885E-03 ! germ cell migration GO:0008354 25 11 1,000 1,848E-04 4,832E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 1,848E-04 4,78E-03 ! regulation of protein complex assembly GO:0043254 117 61 2,000 2,03E-04 5,196E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,215E-04 5,609E-03 ! virus-host interaction GO:0019048 29 12 1,000 2,215E-04 5,55E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,215E-04 5,493E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,215E-04 5,437E-03 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 2,234E-04 5,43E-03 ! lymphocyte mediated immunity GO:0002449 114 64 2,000 2,341E-04 5,632E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,614E-04 6,227E-03 GO:0000725|recombinational repair, ! organelle fusion GO:0048284 32 13 1,000 2,614E-04 6,166E-03 ! endocrine pancreas development GO:0031018 22 13 1,000 2,614E-04 6,106E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,614E-04 6,048E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,614E-04 5,99E-03 ! adaptive immune response GO:0002250 119 67 2,000 2,681E-04 6,085E-03 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 2,000 2,681E-04 6,028E-03 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 2,801E-04 6,24E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,046E-04 6,724E-03 ! intestinal absorption GO:0050892 25 14 1,000 3,046E-04 6,663E-03 ! regulation of RNA stability GO:0043487 32 14 1,000 3,046E-04 6,603E-03 ! humoral immune response GO:0006959 109 71 2,000 3,182E-04 6,835E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 3,182E-04 6,775E-03 ! acute inflammatory response GO:0002526 113 72 2,000 3,316E-04 6,998E-03 ! regulation of exocytosis GO:0017157 22 15 1,000 3,511E-04 7,345E-03 ! cell killing GO:0001906 29 15 1,000 3,511E-04 7,281E-03 ! leukocyte mediated immunity GO:0002443 128 74 2,000 3,595E-04 7,392E-03 ! steroid biosynthetic process GO:0006694 131 76 2,000 3,888E-04 7,928E-03 ! regulation of catabolic process GO:0009894 161 76 2,000 3,888E-04 7,861E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,007E-04 8,035E-03 ! complement activation, alternative pathway GO:0006957 18 16 1,000 4,007E-04 7,968E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,007E-04 7,903E-03 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 4,007E-04 7,839E-03 ! signal complex assembly GO:0007172 41 17 1,000 4,536E-04 8,802E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,536E-04 8,731E-03 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,536E-04 8,662E-03 ! response to hypoxia GO:0001666 171 81 2,000 4,688E-04 8,881E-03 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 4,859E-04 9,134E-03 ! response to oxygen levels GO:0070482 176 83 2,000 5,035E-04 9,391E-03 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,097E-04 9,434E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,097E-04 9,362E-03 ! negative regulation of defense response GO:0031348 25 19 1,000 5,69E-04 0,0103714 ! lipid phosphorylation GO:0046834 35 19 1,000 5,69E-04 0,01029342 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,69E-04 0,0102166 ! visual learning GO:0008542 36 19 1,000 5,69E-04 0,01014092 ! regulation of DNA binding GO:0051101 155 88 2,000 5,974E-04 0,01056884 ! gland development GO:0048732 206 88 2,000 5,974E-04 0,01049169 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,315E-04 0,01100959 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,315E-04 0,01093039 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,315E-04 0,01085231 GO:0010675|regulation of cellular carbohydrate metabolic process, ! retinoid metabolic process GO:0001523 32 20 1,000 6,315E-04 0,01077535 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 1,000 6,315E-04 0,01069946 ! cellular response to starvation GO:0009267 33 20 1,000 6,315E-04 0,01062464 ! detection of chemical stimulus GO:0009593 37 20 1,000 6,315E-04 0,01055086 ! vitamin metabolic process GO:0006766 139 92 2,000 6,801E-04 0,01128463 ! cytolysis GO:0019835 24 21 1,000 6,971E-04 0,01148801 ! vitamin A metabolic process GO:0006776 33 21 1,000 6,971E-04 0,01140986 ! terpenoid metabolic process GO:0006721 37 21 1,000 6,971E-04 0,01133277 ! regulation of membrane potential GO:0042391 164 93 2,000 7,018E-04 0,01133285 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 7,018E-04 0,0112573 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,659E-04 0,0122038 ! protein stabilization GO:0050821 39 22 1,000 7,659E-04 0,01212352 ! positive regulation of immune response GO:0050778 156 96 2,000 7,697E-04 0,01210413 ! positive regulation of DNA replication GO:0045740 43 23 1,000 8,379E-04 0,01309007 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 8,379E-04 0,01300561 ! visual behavior GO:0007632 42 23 1,000 8,379E-04 0,01292224 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 8,379E-04 0,01283994 GO:0042278|purine nucleoside metabolic process, ! sex determination GO:0007530 47 23 1,000 8,379E-04 0,01275867 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,379E-04 0,01267843 ! skeletal muscle tissue development GO:0007519 186 99 2,000 8,416E-04 0,01265624 GO:0060538|skeletal muscle organ development, ! regulation of cellular catabolic process GO:0031329 52 24 1,000 9,129E-04 0,01364291 ! vesicle docking GO:0048278 47 24 1,000 9,129E-04 0,0135587 ! digestive system process GO:0022600 39 24 1,000 9,129E-04 0,01347552 ! protein tetramerization GO:0051262 52 24 1,000 9,129E-04 0,01339335 ! response to starvation GO:0042594 42 25 1,000 9,911E-04 0,01445251 ! receptor metabolic process GO:0043112 46 25 1,000 9,911E-04 0,01436544 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,911E-04 0,01427942 ! macromolecular complex disassembly GO:0032984 53 26 1,000 1,072E-03 0,01535897 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,072E-03 0,01526809 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,072E-03 0,01517827 ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 1,072E-03 0,01508951 ! fat-soluble vitamin metabolic process GO:0006775 40 27 1,000 1,157E-03 0,01618261 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,244E-03 0,01730605 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 1,335E-03 0,01845913 ! membrane docking GO:0022406 61 30 1,000 1,429E-03 0,01964119 ! neurotransmitter secretion GO:0007269 48 30 1,000 1,429E-03 0,0195296 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 1,525E-03 0,02073379 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 1,625E-03 0,0219656 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 1,625E-03 0,02184289 ! positive regulation of catabolic process GO:0009896 64 32 1,000 1,625E-03 0,02172154 ! negative regulation of protein transport GO:0051224 69 33 1,000 1,728E-03 0,02296779 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 2,054E-03 0,02715695 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 2,054E-03 0,02700855 ! negative regulation of DNA binding GO:0043392 68 37 1,000 2,169E-03 0,02836292 ! regulation of protein stability GO:0031647 73 37 1,000 2,169E-03 0,02820961 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 2,287E-03 0,02958147 ! carbohydrate homeostasis GO:0033500 53 38 1,000 2,287E-03 0,02942328 GO:0042593|glucose homeostasis, ! learning GO:0007612 77 39 1,000 2,408E-03 0,03081205 ! Rho protein signal transduction GO:0007266 74 39 1,000 2,408E-03 0,03064902 ! negative regulation of binding GO:0051100 72 40 1,000 2,531E-03 0,03205414 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 2,531E-03 0,03188632 ! maintenance of protein location GO:0045185 91 40 1,000 2,531E-03 0,03172024 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 2,788E-03 0,03475002 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 2,92E-03 0,03621416 ! double-strand break repair GO:0006302 81 44 1,000 3,055E-03 0,0376992 ! maintenance of location in cell GO:0051651 97 44 1,000 3,055E-03 0,03750685 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 3,335E-03 0,04073018 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 3,335E-03 0,04052447 ! positive regulation of protein transport GO:0051222 72 46 1,000 3,335E-03 0,04032083 ! response to calcium ion GO:0051592 81 47 1,000 3,479E-03 0,04185249 ! endosome transport GO:0016197 108 47 1,000 3,479E-03 0,04164427 ! positive regulation of DNA binding GO:0043388 73 47 1,000 3,479E-03 0,04143811 ! cellular component disassembly GO:0022411 86 48 1,000 3,626E-03 0,04297562 ! activation of caspase activity GO:0006919 84 48 1,000 3,626E-03 0,04276495 ! regulation of inflammatory response GO:0050727 75 48 1,000 3,626E-03 0,04255634 ! endocrine system development GO:0035270 104 49 1,000 3,776E-03 0,0440994 ! positive regulation of binding GO:0051099 78 51 1,000 4,084E-03 0,04746787 ! excretion GO:0007588 83 51 1,000 4,084E-03 0,04723965 ! membrane fusion GO:0006944 110 52 1,000 4,242E-03 0,04883608 ! positive regulation of growth GO:0045927 90 52 1,000 4,242E-03 0,04860353 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 4,567E-03 0,0520797 ! positive regulation of caspase activity GO:0043280 95 55 1,000 4,734E-03 0,05372616 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 1,000 4,734E-03 0,05347392 ! heart morphogenesis GO:0003007 97 55 1,000 4,734E-03 0,05322404 ! regulation of DNA replication GO:0006275 101 56 1,000 4,903E-03 0,05487335 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 5,076E-03 0,05653825 ! positive regulation of cell migration GO:0030335 126 57 1,000 5,076E-03 0,05627771 ! lipid modification GO:0030258 97 57 1,000 5,076E-03 0,05601955 ! regulation of intracellular transport GO:0032386 101 57 1,000 5,076E-03 0,05576376 ! maintenance of location GO:0051235 118 57 1,000 5,076E-03 0,05551029 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 5,609E-03 0,06106563 ! nucleoside metabolic process GO:0009116 81 60 1,000 5,609E-03 0,06079056 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 5,609E-03 0,06051796 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 5,609E-03 0,06024779 ! viral reproductive process GO:0022415 126 62 1,000 5,978E-03 0,06392836 ! gonad development GO:0008406 98 62 1,000 5,978E-03 0,0636455 ! positive regulation of cell motion GO:0051272 146 64 1,000 6,358E-03 0,06739354 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 6,749E-03 0,07122218 ! actin filament organization GO:0007015 148 66 1,000 6,749E-03 0,07091117 ! secondary metabolic process GO:0019748 116 66 1,000 6,749E-03 0,07060286 ! cellular hormone metabolic process GO:0034754 113 67 1,000 6,949E-03 0,07237429 ! activation of MAPK activity GO:0000187 115 67 1,000 6,949E-03 0,07206233 ! viral reproduction GO:0016032 134 68 1,000 7,151E-03 0,07383974 ! cAMP-mediated signaling GO:0019933 120 69 1,000 7,355E-03 0,07562918 ! reproductive structure development GO:0048608 113 71 1,000 7,773E-03 0,07958032 ! regulation of caspase activity GO:0043281 122 72 1,000 7,985E-03 0,08141062 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 7,985E-03 0,08106711 ! learning or memory GO:0007611 147 73 1,000 8,201E-03 0,08290214 ! lipoprotein metabolic process GO:0042157 131 73 1,000 8,201E-03 0,08255527 ! regulation of transcription factor activity GO:0051090 126 74 1,000 8,418E-03 0,08439484 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 1,000 8,418E-03 0,08404465 ! meiosis GO:0007126 121 74 1,000 8,418E-03 0,08369736 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 8,418E-03 0,08335293 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 8,639E-03 0,08518458 ! meiotic cell cycle GO:0051321 122 75 1,000 8,639E-03 0,08483688 ! development of primary sexual characteristics GO:0045137 124 76 1,000 8,862E-03 0,08667281 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 9,263E-03 0,0902316 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 9,263E-03 0,08986776 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,263E-03 0,08950685 ! positive regulation of helicase activity GO:0051096 11 5 0,000 9,263E-03 0,08914882 ! neuron fate determination GO:0048664 7 5 0,000 9,263E-03 0,08879365 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,263E-03 0,08844129 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 9,263E-03 0,08809172 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 9,263E-03 0,0877449 ! polyol transport GO:0015791 12 5 0,000 9,263E-03 0,08740081 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 9,263E-03 0,0870594 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,263E-03 0,08672064 ! response to superoxide GO:0000303 10 5 0,000 9,263E-03 0,08638452 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,263E-03 0,08605099 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 9,263E-03 0,08572002 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 9,263E-03 0,08539159 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,263E-03 0,08506567 ! female meiosis GO:0007143 7 5 0,000 9,263E-03 0,08474223 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,263E-03 0,08442123 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,263E-03 0,08410266 ! cobalt ion transport GO:0006824 11 5 0,000 9,263E-03 0,08378649 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 9,263E-03 0,08347268 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 9,263E-03 0,08316121 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 9,263E-03 0,08285206 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,263E-03 0,0825452 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,263E-03 0,08224061 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 9,263E-03 0,08193825 ! embryonic camera-type eye development GO:0031076 10 5 0,000 9,263E-03 0,08163811 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,263E-03 0,08134017 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 9,263E-03 0,08104438 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 9,263E-03 0,08075074 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,263E-03 0,08045923 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,263E-03 0,0801698 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,263E-03 0,07988246 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 9,263E-03 0,07959716 ! negative chemotaxis GO:0050919 14 5 0,000 9,263E-03 0,0793139 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,263E-03 0,07903264 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,263E-03 0,07875338 ! sensory perception of bitter taste GO:0050913 7 5 0,000 9,263E-03 0,07847608 ! behavioral response to pain GO:0048266 9 5 0,000 9,263E-03 0,07820072 ! clathrin coat assembly GO:0048268 14 5 0,000 9,263E-03 0,07792729 ! Notch receptor processing GO:0007220 8 5 0,000 9,263E-03 0,07765577 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,263E-03 0,07738613 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,263E-03 0,07711836 ! micturition GO:0060073 9 5 0,000 9,263E-03 0,07685243 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,263E-03 0,07658833 ! copulation GO:0007620 9 5 0,000 9,263E-03 0,07632605 ! glial cell fate commitment GO:0021781 13 5 0,000 9,263E-03 0,07606555 ! protein maturation by protein folding GO:0022417 13 5 0,000 9,263E-03 0,07580682 ! spermidine metabolic process GO:0008216 7 5 0,000 9,263E-03 0,07554985 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,263E-03 0,07529461 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,263E-03 0,0750411 ! apoptotic cell clearance GO:0043277 20 5 0,000 9,263E-03 0,07478928 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,263E-03 0,07453915 ! grooming behavior GO:0007625 6 5 0,000 9,263E-03 0,07429068 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,263E-03 0,07404387 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 9,263E-03 0,07379869 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,263E-03 0,07355513 ! response to protozoan GO:0001562 10 5 0,000 9,263E-03 0,07331318 ! lymph vessel development GO:0001945 10 5 0,000 9,263E-03 0,0730728 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 9,263E-03 0,072834 ! endochondral ossification GO:0001958 16 5 0,000 9,263E-03 0,07259676 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,263E-03 0,07236106 ! parathyroid gland development GO:0060017 13 5 0,000 9,263E-03 0,07212688 ! anagen GO:0042640 6 5 0,000 9,263E-03 0,07189421 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,263E-03 0,07166304 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,263E-03 0,07143335 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 9,263E-03 0,07120513 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 9,263E-03 0,07097836 ! dorsal spinal cord development GO:0021516 7 5 0,000 9,263E-03 0,07075303 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 9,263E-03 0,07052913 ! sphingoid catabolic process GO:0046521 6 5 0,000 9,263E-03 0,07030664 ! skeletal myofibril assembly GO:0014866 10 5 0,000 9,263E-03 0,07008555 ! smooth muscle tissue development GO:0048745 28 5 0,000 9,263E-03 0,06986585 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,263E-03 0,06964752 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,263E-03 0,06943055 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,263E-03 0,06921492 ! cardiac muscle fiber development GO:0048739 10 5 0,000 9,263E-03 0,06900064 ! transepithelial chloride transport GO:0030321 9 5 0,000 9,263E-03 0,06878767 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,263E-03 0,06857602 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 9,263E-03 0,06836566 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 9,263E-03 0,06815659 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,263E-03 0,0679488 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,263E-03 0,06774227 ! histidine catabolic process GO:0006548 6 5 0,000 9,263E-03 0,06753699 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 9,263E-03 0,06733295 ! microvillus organization GO:0032528 7 5 0,000 9,263E-03 0,06713014 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 9,263E-03 0,06692854 ! L-serine biosynthetic process GO:0006564 6 5 0,000 9,263E-03 0,06672816 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,263E-03 0,06652897 ! tryptophan metabolic process GO:0006568 9 5 0,000 9,263E-03 0,06633097 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 9,263E-03 0,06613414 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,263E-03 0,06593848 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 9,263E-03 0,06574397 ! polyol catabolic process GO:0046174 7 5 0,000 9,263E-03 0,0655506 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 9,263E-03 0,06535837 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,263E-03 0,06516727 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,263E-03 0,06497728 ! muscle cell migration GO:0014812 8 5 0,000 9,263E-03 0,06478839 ! mitochondrial fission GO:0000266 8 5 0,000 9,263E-03 0,0646006 ! sister chromatid cohesion GO:0007062 12 5 0,000 9,263E-03 0,06441389 ! mRNA transcription GO:0009299 9 5 0,000 9,263E-03 0,06422826 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 9,263E-03 0,06404369 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 9,263E-03 0,06386019 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 9,263E-03 0,06367773 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,263E-03 0,06349631 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,263E-03 0,06331592 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,263E-03 0,06313656 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,263E-03 0,06295821 ! response to food GO:0032094 6 5 0,000 9,263E-03 0,06278086 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,263E-03 0,06260451 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,263E-03 0,06242915 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 9,263E-03 0,06225476 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,263E-03 0,06208135 ! paraxial mesoderm development GO:0048339 14 5 0,000 9,263E-03 0,0619089 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 9,263E-03 0,06173741 ! forebrain neuron development GO:0021884 13 5 0,000 9,263E-03 0,06156687 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 9,263E-03 0,06139726 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,263E-03 0,06122859 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,263E-03 0,06106084 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,263E-03 0,060894 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 9,263E-03 0,06072808 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,263E-03 0,06056306 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 9,263E-03 0,06039893 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 9,263E-03 0,06023569 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 9,263E-03 0,06007333 ! basic amino acid transport GO:0015802 11 5 0,000 9,263E-03 0,05991184 ! cellular glucose homeostasis GO:0001678 5 5 0,000 9,263E-03 0,05975122 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,263E-03 0,05959146 ! depyrimidination GO:0045008 10 5 0,000 9,263E-03 0,05943255 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,263E-03 0,05927448 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,263E-03 0,05911726 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,263E-03 0,05896086 ! zinc ion homeostasis GO:0055069 8 5 0,000 9,263E-03 0,05880529 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 9,263E-03 0,05865054 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 9,263E-03 0,0584966 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,263E-03 0,05834347 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,263E-03 0,05819114 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,263E-03 0,0580396 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 9,263E-03 0,05788885 ! peptidyl-arginine modification GO:0018195 9 5 0,000 9,263E-03 0,05773887 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,263E-03 0,05758968 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,263E-03 0,05744125 ! response to arsenic GO:0046685 10 5 0,000 9,263E-03 0,05729359 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 9,263E-03 0,05714668 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 9,263E-03 0,05700053 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 9,263E-03 0,05685512 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 9,263E-03 0,05671045 ! response to cadmium ion GO:0046686 7 5 0,000 9,263E-03 0,05656651 ! bile acid biosynthetic process GO:0006699 6 5 0,000 9,263E-03 0,0564233 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 9,263E-03 0,05628082 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,263E-03 0,05613906 ! decidualization GO:0046697 11 5 0,000 9,263E-03 0,055998 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 9,263E-03 0,05585766 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 9,263E-03 0,05571801 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,263E-03 0,05557907 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,263E-03 0,05544081 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 9,263E-03 0,05530324 ! base conversion or substitution editing GO:0016553 5 5 0,000 9,263E-03 0,05516635 ! neural tube patterning GO:0021532 7 5 0,000 9,263E-03 0,05503014 ! embryonic cleavage GO:0040016 6 5 0,000 9,263E-03 0,05489459 ! peroxisome fission GO:0016559 5 5 0,000 9,263E-03 0,05475972 ! histone demethylation GO:0016577 10 5 0,000 9,263E-03 0,0546255 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 9,263E-03 0,05449194 ! mitotic recombination GO:0006312 9 5 0,000 9,263E-03 0,05435904 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,263E-03 0,05422678 ! metaphase plate congression GO:0051310 7 5 0,000 9,263E-03 0,05409516 ! regulation of sterol transport GO:0032371 7 5 0,000 9,263E-03 0,05396418 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,263E-03 0,05383383 ! enteric nervous system development GO:0048484 8 5 0,000 9,263E-03 0,05370411 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 9,263E-03 0,05357501 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 9,263E-03 0,05344654 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 9,263E-03 0,05331867 ! muscle cell proliferation GO:0033002 11 5 0,000 9,263E-03 0,05319142 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,263E-03 0,05306477 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 9,263E-03 0,05293873 ! plasminogen activation GO:0031639 5 5 0,000 9,263E-03 0,05281328 ! B cell homeostasis GO:0001782 13 5 0,000 9,263E-03 0,05268843 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 9,263E-03 0,05256416 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,263E-03 0,05244048 ! metaphase GO:0051323 8 5 0,000 9,263E-03 0,05231738 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 9,263E-03 0,05219486 ! cellular response to nutrient GO:0031670 8 5 0,000 9,263E-03 0,05207291 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,263E-03 0,05195153 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,263E-03 0,05183071 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,263E-03 0,05171045 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 9,263E-03 0,05159075 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 9,263E-03 0,05147161 ! response to redox state GO:0051775 5 5 0,000 9,263E-03 0,05135301 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 9,263E-03 0,05123495 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 9,263E-03 0,05111744 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,263E-03 0,05100047 ! regulation of telomerase activity GO:0051972 6 5 0,000 9,263E-03 0,05088403 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,263E-03 0,05076812 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 9,263E-03 0,05065274 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,263E-03 0,05053788 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 9,263E-03 0,05042354 ! striatum development GO:0021756 9 5 0,000 9,263E-03 0,05030972 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 9,263E-03 0,05019641 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 9,263E-03 0,05008361 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,263E-03 0,04997131 ! glial cell migration GO:0008347 11 5 0,000 9,263E-03 0,04985952 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,263E-03 0,04974823 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 9,263E-03 0,04963743 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,263E-03 0,04952712 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,263E-03 0,04941731 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,263E-03 0,04930798 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,263E-03 0,04919913 ! neuroprotection GO:0043526 6 5 0,000 9,263E-03 0,04909076 ! neural plate development GO:0001840 8 5 0,000 9,263E-03 0,04898287 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 9,263E-03 0,04887545 ! regulation of sensory perception GO:0051931 7 5 0,000 9,263E-03 0,0487685 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,263E-03 0,04866202 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,263E-03 0,048556 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 9,263E-03 0,04845045 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 9,263E-03 0,04834535 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,263E-03 0,0482407 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,263E-03 0,04813651 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,263E-03 0,04803277 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,263E-03 0,04792947 ! spindle assembly GO:0051225 6 5 0,000 9,263E-03 0,04782662 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 9,263E-03 0,04772421 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,263E-03 0,04762223 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,263E-03 0,04752069 ! drug metabolic process GO:0017144 6 5 0,000 9,263E-03 0,04741959 ! stem cell division GO:0017145 11 5 0,000 9,263E-03 0,04731891 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,263E-03 0,04721866 ! organ regeneration GO:0031100 7 5 0,000 9,263E-03 0,04711883 ! carnitine metabolic process GO:0009437 7 5 0,000 9,263E-03 0,04701942 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 9,263E-03 0,04692043 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,263E-03 0,04682186 ! blood coagulation GO:0007596 146 78 1,000 9,315E-03 0,04698735 GO:0050817|coagulation, ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 9,779E-03 0,04922371 ! response to metal ion GO:0010038 140 80 1,000 9,779E-03 0,04912094 ! digestion GO:0007586 112 81 1,000 0,01001498 0,0502001 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,01025321 0,05128736 ! response to drug GO:0042493 143 82 1,000 0,01025321 0,05118095 ! response to nutrient GO:0007584 125 82 1,000 0,01025321 0,05107499 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,01025321 0,05096946 ! regulation of lyase activity GO:0051339 160 83 1,000 0,01049394 0,0520586 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,01073717 0,05315563 ! hemostasis GO:0007599 158 84 1,000 0,01073717 0,05304648 ! negative regulation of transport GO:0051051 153 84 1,000 0,01073717 0,05293778 ! nucleosome assembly GO:0006334 122 85 1,000 0,01098289 0,05403852 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01110567 0,05453113 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01110567 0,05442007 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01110567 0,05430946 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01110567 0,0541993 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01110567 0,05408958 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01110567 0,05398031 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01110567 0,05387148 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01110567 0,05376308 ! sleep GO:0030431 13 6 0,000 0,01110567 0,05365513 ! response to oxygen radical GO:0000305 11 6 0,000 0,01110567 0,0535476 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01110567 0,05344051 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01110567 0,05333384 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01110567 0,05322759 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01110567 0,05312177 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01110567 0,05301637 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01110567 0,05291139 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01110567 0,05280682 ! forebrain regionalization GO:0021871 8 6 0,000 0,01110567 0,05270267 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01110567 0,05259892 ! male meiosis GO:0007140 7 6 0,000 0,01110567 0,05249558 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01110567 0,05239265 ! response to zinc ion GO:0010043 9 6 0,000 0,01110567 0,05229012 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01110567 0,05218799 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01110567 0,05208626 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01110567 0,05198493 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01110567 0,05188399 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01110567 0,05178344 ! malate metabolic process GO:0006108 11 6 0,000 0,01110567 0,05168327 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01110567 0,0515835 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01110567 0,05148411 ! protein refolding GO:0042026 15 6 0,000 0,01110567 0,0513851 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01110567 0,05128647 ! opsonization GO:0008228 8 6 0,000 0,01110567 0,05118822 ! mating behavior GO:0007617 7 6 0,000 0,01110567 0,05109035 ! neuron remodeling GO:0016322 15 6 0,000 0,01110567 0,05099285 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01110567 0,05089572 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01110567 0,05079896 ! equilibrioception GO:0050957 14 6 0,000 0,01110567 0,05070257 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01110567 0,05060654 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01110567 0,05051087 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01110567 0,05041557 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01110567 0,05032063 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01110567 0,05022604 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01110567 0,05013181 ! toxin metabolic process GO:0009404 11 6 0,000 0,01110567 0,05003793 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01110567 0,0499444 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01110567 0,04985122 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01110567 0,04975838 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01110567 0,0496659 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01110567 0,04957375 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01110567 0,04948195 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01110567 0,04939049 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01110567 0,04929936 ! thymic T cell selection GO:0045061 12 6 0,000 0,01110567 0,04920857 ! protein lipoylation GO:0009249 10 6 0,000 0,01110567 0,04911811 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01110567 0,04902799 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01110567 0,04893819 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01110567 0,04884872 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01110567 0,04875958 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01110567 0,04867077 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01110567 0,04858228 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01110567 0,04849411 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01110567 0,04840625 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01110567 0,04831872 ! hyperosmotic response GO:0006972 9 6 0,000 0,01110567 0,0482315 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01110567 0,0481446 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01110567 0,04805801 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01110567 0,04797173 ! urea metabolic process GO:0019627 7 6 0,000 0,01110567 0,04788576 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01110567 0,04780009 ! neutrophil activation GO:0042119 8 6 0,000 0,01110567 0,04771474 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01110567 0,04762968 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01110567 0,04754493 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01110567 0,04746048 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01110567 0,04737633 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01110567 0,04729248 ! neuron apoptosis GO:0051402 9 6 0,000 0,01110567 0,04720893 ! nucleoside salvage GO:0043174 9 6 0,000 0,01110567 0,04712567 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01110567 0,0470427 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01110567 0,04696002 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01110567 0,04687764 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01110567 0,04679554 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01110567 0,04671373 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01110567 0,0466322 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01110567 0,04655096 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01110567 0,04647 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01110567 0,04638933 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01110567 0,04630893 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01110567 0,04622881 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01110567 0,04614897 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01110567 0,0460694 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01110567 0,04599011 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01110567 0,04591109 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01110567 0,04583234 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01110567 0,04575386 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01110567 0,04567565 ! neural nucleus development GO:0048857 14 6 0,000 0,01110567 0,0455977 ! response to UV-C GO:0010225 11 6 0,000 0,01110567 0,04552002 ! astrocyte development GO:0014002 15 6 0,000 0,01110567 0,04544261 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01110567 0,04536545 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01110567 0,04528856 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01110567 0,04521193 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01110567 0,04513556 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01110567 0,04505945 ! response to copper ion GO:0046688 10 6 0,000 0,01110567 0,04498359 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01110567 0,04490799 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01110567 0,04483264 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01110567 0,04475754 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01110567 0,0446827 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01110567 0,0446081 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01110567 0,04453375 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01110567 0,04445965 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01110567 0,0443858 ! hair follicle maturation GO:0048820 7 6 0,000 0,01110567 0,04431219 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01110567 0,04423883 ! Schwann cell development GO:0014044 15 6 0,000 0,01110567 0,04416571 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01110567 0,04409283 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01110567 0,04402019 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01110567 0,04394778 ! subpallium development GO:0021544 10 6 0,000 0,01110567 0,04387562 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01110567 0,04380369 ! histone ubiquitination GO:0016574 8 6 0,000 0,01110567 0,043732 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01110567 0,04366054 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01110567 0,04358932 ! G2 phase GO:0051319 16 6 0,000 0,01110567 0,04351833 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01110567 0,04344757 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01110567 0,04337703 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01110567 0,04330673 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01110567 0,04323665 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01110567 0,04316681 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01110567 0,04309718 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01110567 0,04302778 ! receptor internalization GO:0031623 10 6 0,000 0,01110567 0,04295861 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01110567 0,04288965 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01110567 0,04282092 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01110567 0,0427524 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01110567 0,04268411 ! protein deubiquitination GO:0016579 14 6 0,000 0,01110567 0,04261603 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01110567 0,04254817 ! protein destabilization GO:0031648 9 6 0,000 0,01110567 0,04248053 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01110567 0,0424131 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01110567 0,04234588 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01110567 0,04227888 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01110567 0,04221209 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01110567 0,04214551 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01110567 0,04207914 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01110567 0,04201298 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01110567 0,04194702 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01110567 0,04188127 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01110567 0,04181573 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01110567 0,04175039 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01110567 0,04168526 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01110567 0,04162033 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01110567 0,0415556 ! catecholamine transport GO:0051937 9 6 0,000 0,01110567 0,04149108 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01110567 0,04142675 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01110567 0,04136262 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01110567 0,04129869 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01110567 0,04123496 ! maternal placenta development GO:0001893 12 6 0,000 0,01110567 0,04117142 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01110567 0,04110808 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01110567 0,04104493 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01110567 0,04098198 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01110567 0,04091922 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01110567 0,04085666 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01110567 0,04079428 ! response to inorganic substance GO:0010035 153 86 1,000 0,01123109 0,04119207 ! chromatin assembly GO:0031497 124 86 1,000 0,01123109 0,04112938 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,01148175 0,04198344 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 1,000 0,01148175 0,04191973 GO:0070201|regulation of establishment of protein localization, ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,01224847 0,04465122 ! sex differentiation GO:0007548 145 90 1,000 0,01224847 0,04458367 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,01224847 0,04451632 ! regulation of defense response GO:0031347 149 92 1,000 0,01277177 0,04634824 ! nucleosome organization GO:0034728 138 92 1,000 0,01277177 0,04627843 ! tRNA transcription GO:0009304 14 7 0,000 0,01294481 0,04683489 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01294481 0,04676457 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01294481 0,04669446 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01294481 0,04662455 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01294481 0,04655486 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01294481 0,04648538 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01294481 0,0464161 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01294481 0,04634703 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01294481 0,04627816 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01294481 0,0462095 ! prostate gland development GO:0030850 13 7 0,000 0,01294481 0,04614104 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01294481 0,04607278 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01294481 0,04600473 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01294481 0,04593688 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01294481 0,04586922 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01294481 0,04580177 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01294481 0,04573451 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01294481 0,04566745 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01294481 0,04560059 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01294481 0,04553392 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01294481 0,04546745 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01294481 0,04540117 ! glycolipid transport GO:0046836 10 7 0,000 0,01294481 0,04533508 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01294481 0,04526919 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01294481 0,04520349 ! neuron adhesion GO:0007158 12 7 0,000 0,01294481 0,04513797 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01294481 0,04507265 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01294481 0,04500752 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01294481 0,04494257 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01294481 0,04487781 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01294481 0,04481324 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01294481 0,04474885 ! mRNA stabilization GO:0048255 18 7 0,000 0,01294481 0,04468465 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01294481 0,04462063 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01294481 0,0445568 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01294481 0,04449315 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01294481 0,04442968 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01294481 0,04436639 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01294481 0,04430328 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01294481 0,04424034 ! lipoprotein transport GO:0042953 14 7 0,000 0,01294481 0,04417759 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01294481 0,04411502 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01294481 0,04405262 ! rhythmic behavior GO:0007622 15 7 0,000 0,01294481 0,0439904 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01294481 0,04392835 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01294481 0,04386648 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01294481 0,04380479 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01294481 0,04374326 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01294481 0,04368191 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01294481 0,04362073 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01294481 0,04355972 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01294481 0,04349889 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01294481 0,04343822 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01294481 0,04337772 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01294481 0,04331739 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01294481 0,04325723 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01294481 0,04319723 ! spinal cord patterning GO:0021511 13 7 0,000 0,01294481 0,0431374 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01294481 0,04307773 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01294481 0,04301824 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01294481 0,0429589 ! adrenal gland development GO:0030325 17 7 0,000 0,01294481 0,04289973 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01294481 0,04284072 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01294481 0,04278187 ! ovulation GO:0030728 9 7 0,000 0,01294481 0,04272319 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01294481 0,04266466 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01294481 0,0426063 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01294481 0,04254809 ! microtubule nucleation GO:0007020 20 7 0,000 0,01294481 0,04249004 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01294481 0,04243216 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01294481 0,04237443 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01294481 0,04231685 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01294481 0,04225943 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01294481 0,04220217 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01294481 0,04214506 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01294481 0,04208811 ! galactose metabolic process GO:0006012 13 7 0,000 0,01294481 0,04203131 ! response to dietary excess GO:0002021 8 7 0,000 0,01294481 0,04197467 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01294481 0,04191817 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01294481 0,04186183 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01294481 0,04180564 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01294481 0,0417496 ! organ growth GO:0035265 15 7 0,000 0,01294481 0,04169371 ! purine salvage GO:0043101 10 7 0,000 0,01294481 0,04163797 ! nucleoside transport GO:0015858 8 7 0,000 0,01294481 0,04158238 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01294481 0,04152694 ! parturition GO:0007567 14 7 0,000 0,01294481 0,04147164 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01294481 0,04141649 ! rRNA modification GO:0000154 14 7 0,000 0,01294481 0,04136149 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01294481 0,04130663 ! spindle checkpoint GO:0031577 15 7 0,000 0,01294481 0,04125192 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01294481 0,04119736 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01294481 0,04114294 ! macrophage differentiation GO:0030225 11 7 0,000 0,01294481 0,04108866 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01294481 0,04103452 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01294481 0,04098053 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01294481 0,04092668 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01294481 0,04087297 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01294481 0,0408194 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01294481 0,04076597 ! fibrinolysis GO:0042730 10 7 0,000 0,01294481 0,04071268 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01294481 0,04065953 ! eating behavior GO:0042755 7 7 0,000 0,01294481 0,04060652 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01294481 0,04055365 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01294481 0,04050091 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01294481 0,04044831 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01294481 0,04039585 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01294481 0,04034353 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01294481 0,04029134 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01294481 0,04023928 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01294481 0,04018736 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01294481 0,04013557 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01294481 0,04008392 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01294481 0,04003239 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01294481 0,039981 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01294481 0,03992975 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01294481 0,03987862 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01294481 0,03982762 ! regulation of meiosis GO:0040020 12 7 0,000 0,01294481 0,03977676 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01294481 0,03972602 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01294481 0,03967542 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01294481 0,03962494 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01294481 0,03957459 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01294481 0,03952437 ! transcription termination GO:0006353 13 7 0,000 0,01294481 0,03947427 ! response to tumor cell GO:0002347 13 7 0,000 0,01294481 0,03942431 ! anaphase GO:0051322 17 7 0,000 0,01294481 0,03937447 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01294481 0,03932475 ! axonal fasciculation GO:0007413 18 7 0,000 0,01294481 0,03927516 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01294481 0,0392257 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01294481 0,03917636 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01294481 0,03912714 ! diuresis GO:0030146 12 7 0,000 0,01294481 0,03907805 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01294481 0,03902908 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01294481 0,03898023 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01294481 0,0389315 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01294481 0,0388829 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01294481 0,03883442 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01294481 0,03878606 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01294481 0,03873781 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01294481 0,03868969 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01294481 0,03864169 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01294481 0,03859381 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01294481 0,03854604 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01294481 0,0384984 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01294481 0,03845087 ! lymph node development GO:0048535 10 7 0,000 0,01294481 0,03840346 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01294481 0,03835616 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01294481 0,03830898 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01294481 0,03826192 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01294481 0,03821497 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01294481 0,03816814 ! adult feeding behavior GO:0008343 9 7 0,000 0,01294481 0,03812142 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01294481 0,03807482 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01294481 0,03802833 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01294481 0,03798195 ! muscle adaptation GO:0043500 14 7 0,000 0,01294481 0,03793569 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01294481 0,03788954 ! retina homeostasis GO:0001895 12 7 0,000 0,01294481 0,0378435 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01294481 0,03779758 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01294481 0,03775176 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01294481 0,03770606 ! protein prenylation GO:0018342 18 7 0,000 0,01294481 0,03766046 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01294481 0,03761498 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,01303704 0,03783731 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,01303704 0,03779172 ! forebrain development GO:0030900 188 95 1,000 0,01357478 0,03930317 ! detection of stimulus GO:0051606 151 96 1,000 0,01384723 0,0400438 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,01412205 0,04078951 ! hormone metabolic process GO:0042445 157 97 1,000 0,01412205 0,0407406 ! regulation of protein localization GO:0032880 176 97 1,000 0,01412205 0,04069181 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,01467878 0,04224538 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01478058 0,04248754 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01478058 0,04243684 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01478058 0,04238626 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01478058 0,0423358 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01478058 0,04228546 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01478058 0,04223524 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01478058 0,04218514 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01478058 0,04213515 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01478058 0,04208529 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01478058 0,04203554 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01478058 0,04198591 ! meiotic prophase I GO:0007128 13 8 0,000 0,01478058 0,0419364 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01478058 0,04188701 ! oligopeptide transport GO:0006857 15 8 0,000 0,01478058 0,04183773 ! UTP metabolic process GO:0046051 8 8 0,000 0,01478058 0,04178857 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01478058 0,04173952 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01478058 0,04169059 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01478058 0,04164177 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01478058 0,04159306 ! succinate metabolic process GO:0006105 14 8 0,000 0,01478058 0,04154447 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01478058 0,041496 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01478058 0,04144763 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01478058 0,04139938 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01478058 0,04135124 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01478058 0,04130322 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01478058 0,0412553 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01478058 0,0412075 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01478058 0,0411598 ! reflex GO:0060004 16 8 0,000 0,01478058 0,04111222 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01478058 0,04106475 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01478058 0,04101738 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01478058 0,04097013 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01478058 0,04092298 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01478058 0,04087594 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01478058 0,04082901 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01478058 0,04078219 ! pigment granule organization GO:0048753 16 8 0,000 0,01478058 0,04073547 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01478058 0,04068887 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01478058 0,04064237 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01478058 0,04059597 ! histidine metabolic process GO:0006547 16 8 0,000 0,01478058 0,04054968 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01478058 0,0405035 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01478058 0,04045742 ! glycine catabolic process GO:0006546 13 8 0,000 0,01478058 0,04041144 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01478058 0,04036557 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01478058 0,04031981 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01478058 0,04027414 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01478058 0,04022859 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01478058 0,04018313 ! melanin metabolic process GO:0006582 15 8 0,000 0,01478058 0,04013778 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01478058 0,04009252 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01478058 0,04004738 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01478058 0,04000233 ! macrophage activation GO:0042116 12 8 0,000 0,01478058 0,03995738 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01478058 0,03991254 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01478058 0,03986779 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01478058 0,03982315 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01478058 0,0397786 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01478058 0,03973416 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01478058 0,03968981 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01478058 0,03964556 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01478058 0,03960141 ! osteoblast development GO:0002076 16 8 0,000 0,01478058 0,03955736 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01478058 0,03951341 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01478058 0,03946956 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01478058 0,0394258 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01478058 0,03938214 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01478058 0,03933857 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01478058 0,0392951 ! response to UV-B GO:0010224 16 8 0,000 0,01478058 0,03925173 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01478058 0,03920846 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01478058 0,03916527 ! intermediate filament organization GO:0045109 12 8 0,000 0,01478058 0,03912219 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01478058 0,0390792 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01478058 0,0390363 ! cellular extravasation GO:0045123 12 8 0,000 0,01478058 0,0389935 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01478058 0,03895079 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01478058 0,03890817 ! response to antibiotic GO:0046677 11 8 0,000 0,01478058 0,03886565 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01478058 0,03882322 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01478058 0,03878088 ! DNA topological change GO:0006265 12 8 0,000 0,01478058 0,03873864 ! response to tropane GO:0014073 15 8 0,000 0,01478058 0,03869648 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01478058 0,03865442 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01478058 0,03861245 ! melanosome transport GO:0032402 13 8 0,000 0,01478058 0,03857057 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01478058 0,03852879 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01478058 0,03848709 ! mast cell activation GO:0045576 14 8 0,000 0,01478058 0,03844548 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01478058 0,03840396 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01478058 0,03836253 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01478058 0,0383212 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01478058 0,03827995 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01478058 0,03823878 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01478058 0,03819771 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01478058 0,03815673 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01478058 0,03811583 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01478058 0,03807502 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01478058 0,0380343 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01478058 0,03799366 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01478058 0,03795312 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01478058 0,03791265 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01478058 0,03787228 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01478058 0,03783199 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01478058 0,03779178 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01478058 0,03775167 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01478058 0,03771163 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01478058 0,03767168 ! hormone catabolic process GO:0042447 17 8 0,000 0,01478058 0,03763182 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01478058 0,03759204 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01478058 0,03755234 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01478058 0,03751273 ! ATP catabolic process GO:0006200 11 8 0,000 0,01478058 0,0374732 ! blastocyst growth GO:0001832 19 8 0,000 0,01478058 0,03743376 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01478058 0,03739439 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01478058 0,03735512 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01478058 0,03731592 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01478058 0,0372768 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01478058 0,03723777 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01478058 0,03719882 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01478058 0,03715995 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01478058 0,03712116 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01478058 0,03708245 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01478058 0,03704382 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01478058 0,03700528 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01478058 0,03696681 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01478058 0,03692842 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01478058 0,03689011 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01478058 0,03685189 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01478058 0,03681374 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01478058 0,03677567 ! axon extension GO:0048675 15 9 0,000 0,016613 0,04129222 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,016613 0,04124961 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,016613 0,04120708 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,016613 0,04116464 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,016613 0,04112229 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,016613 0,04108003 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,016613 0,04103785 ! phosphate transport GO:0006817 19 9 0,000 0,016613 0,04099576 ! reproductive behavior GO:0019098 19 9 0,000 0,016613 0,04095376 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,016613 0,04091184 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,016613 0,04087001 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,016613 0,04082826 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,016613 0,0407866 ! GTP metabolic process GO:0046039 9 9 0,000 0,016613 0,04074502 ! RNA methylation GO:0001510 15 9 0,000 0,016613 0,04070353 ! elastic fiber assembly GO:0048251 15 9 0,000 0,016613 0,04066212 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,016613 0,0406208 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,016613 0,04057956 ! artery development GO:0060840 24 9 0,000 0,016613 0,04053841 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,016613 0,04049733 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,016613 0,04045634 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,016613 0,04041544 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,016613 0,04037461 ! chemosensory behavior GO:0007635 20 9 0,000 0,016613 0,04033387 ! microtubule bundle formation GO:0001578 21 9 0,000 0,016613 0,04029321 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,016613 0,04025264 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,016613 0,04021214 ! leukocyte degranulation GO:0043299 16 9 0,000 0,016613 0,04017173 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,016613 0,04013139 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,016613 0,04009114 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,016613 0,04005097 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,016613 0,04001088 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,016613 0,03997087 ! protein targeting to ER GO:0045047 22 9 0,000 0,016613 0,03993094 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,016613 0,03989109 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,016613 0,03985131 ! T cell selection GO:0045058 23 9 0,000 0,016613 0,03981162 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,016613 0,03977201 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,016613 0,03973247 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,016613 0,03969302 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,016613 0,03965364 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,016613 0,03961434 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,016613 0,03957512 ! mannose metabolic process GO:0006013 13 9 0,000 0,016613 0,03953597 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,016613 0,03949691 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,016613 0,03945792 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,016613 0,039419 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,016613 0,03938017 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,016613 0,03934141 ! ruffle organization GO:0031529 15 9 0,000 0,016613 0,03930272 ! behavioral fear response GO:0001662 22 9 0,000 0,016613 0,03926411 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,016613 0,03922558 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,016613 0,03918713 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,016613 0,03914874 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,016613 0,03911044 ! oligodendrocyte development GO:0014003 10 9 0,000 0,016613 0,03907221 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,016613 0,03903405 ! segment specification GO:0007379 13 9 0,000 0,016613 0,03899597 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,016613 0,03895796 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,016613 0,03892003 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,016613 0,03888217 ! response to amine stimulus GO:0014075 13 9 0,000 0,016613 0,03884438 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,016613 0,03880667 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,016613 0,03876903 ! erythrocyte development GO:0048821 15 9 0,000 0,016613 0,03873146 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,016613 0,03869397 ! renal water homeostasis GO:0003091 14 9 0,000 0,016613 0,03865655 ! postreplication repair GO:0006301 22 9 0,000 0,016613 0,0386192 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,016613 0,03858192 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,016613 0,03854471 ! icosanoid secretion GO:0032309 15 9 0,000 0,016613 0,03850758 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,016613 0,03847052 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,016613 0,03843353 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,016613 0,03839661 ! regulation of cell division GO:0051302 15 9 0,000 0,016613 0,03835976 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,016613 0,03832298 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,016613 0,03828627 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,016613 0,03824963 ! sterol catabolic process GO:0016127 11 9 0,000 0,016613 0,03821307 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,016613 0,03817657 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,016613 0,03814014 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,016613 0,03810378 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,016613 0,03806749 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,016613 0,03803127 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,016613 0,03799512 ! musculoskeletal movement GO:0050881 14 9 0,000 0,016613 0,03795904 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,016613 0,03792302 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,016613 0,03788708 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,016613 0,0378512 ! purine base metabolic process GO:0006144 21 9 0,000 0,016613 0,03781539 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,016613 0,03777965 ! pigment granule transport GO:0051904 17 9 0,000 0,016613 0,03774397 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,016613 0,03770837 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,016613 0,03767283 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,016613 0,03763735 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,016613 0,03760195 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,016613 0,03756661 ! mitochondrion localization GO:0051646 15 9 0,000 0,016613 0,03753133 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01844207 0,0416244 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01844207 0,04158539 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01844207 0,04154645 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01844207 0,04150759 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01844207 0,0414688 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01844207 0,04143008 ! synapsis GO:0007129 13 10 0,000 0,01844207 0,04139143 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01844207 0,04135285 ! N-glycan processing GO:0006491 20 10 0,000 0,01844207 0,04131435 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01844207 0,04127592 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01844207 0,04123756 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01844207 0,04119927 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01844207 0,04116105 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01844207 0,0411229 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01844207 0,04108483 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01844207 0,04104682 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01844207 0,04100888 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01844207 0,04097102 ! androgen metabolic process GO:0008209 17 10 0,000 0,01844207 0,04093322 ! phospholipid efflux GO:0033700 16 10 0,000 0,01844207 0,0408955 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01844207 0,04085784 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01844207 0,04082025 ! lung alveolus development GO:0048286 26 10 0,000 0,01844207 0,04078273 ! pathogenesis GO:0009405 13 10 0,000 0,01844207 0,04074528 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01844207 0,0407079 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01844207 0,04067059 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01844207 0,04063335 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01844207 0,04059617 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01844207 0,04055906 ! endoderm development GO:0007492 16 10 0,000 0,01844207 0,04052202 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01844207 0,04048505 ! arginine catabolic process GO:0006527 13 10 0,000 0,01844207 0,04044814 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01844207 0,04041131 ! proline metabolic process GO:0006560 13 10 0,000 0,01844207 0,04037453 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01844207 0,04033783 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01844207 0,04030119 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01844207 0,04026462 ! V(D)J recombination GO:0033151 28 10 0,000 0,01844207 0,04022812 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01844207 0,04019168 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01844207 0,04015531 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01844207 0,040119 ! B cell proliferation GO:0042100 18 10 0,000 0,01844207 0,04008276 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01844207 0,04004658 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01844207 0,04001047 ! multicellular organism growth GO:0035264 18 10 0,000 0,01844207 0,03997443 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01844207 0,03993845 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01844207 0,03990253 ! epithelial cell development GO:0002064 20 10 0,000 0,01844207 0,03986668 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01844207 0,03983089 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01844207 0,03979517 ! macroautophagy GO:0016236 17 10 0,000 0,01844207 0,03975951 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01844207 0,03972392 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01844207 0,03968838 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01844207 0,03965292 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01844207 0,03961751 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01844207 0,03958217 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01844207 0,03954689 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01844207 0,03951168 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01844207 0,03947652 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01844207 0,03944143 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01844207 0,03940641 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01844207 0,03937144 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01844207 0,03933654 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01844207 0,03930169 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01844207 0,03926691 ! response to dsRNA GO:0043331 20 10 0,000 0,01844207 0,0392322 ! DNA ligation GO:0006266 19 10 0,000 0,01844207 0,03919754 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01844207 0,03916294 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01844207 0,03912841 ! melanosome localization GO:0032400 16 10 0,000 0,01844207 0,03909393 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01844207 0,03905952 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01844207 0,03902517 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01844207 0,03899087 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01844207 0,03895664 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01844207 0,03892247 ! mRNA cleavage GO:0006379 17 10 0,000 0,01844207 0,03888836 ! protein sumoylation GO:0016925 15 10 0,000 0,01844207 0,0388543 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01844207 0,03882031 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01844207 0,03878638 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01844207 0,0387525 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01844207 0,03871869 ! salivary gland development GO:0007431 27 10 0,000 0,01844207 0,03868493 ! prophase GO:0051324 15 10 0,000 0,01844207 0,03865123 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01844207 0,03861759 ! apical protein localization GO:0045176 15 10 0,000 0,01844207 0,03858401 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01844207 0,03855049 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01844207 0,03851703 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01844207 0,03848362 ! midbrain development GO:0030901 13 10 0,000 0,01844207 0,03845027 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01844207 0,03841698 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01844207 0,03838375 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01844207 0,03835057 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01844207 0,03831746 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01844207 0,03828439 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01844207 0,03825139 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01844207 0,03821844 ! oocyte development GO:0048599 17 10 0,000 0,01844207 0,03818555 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01844207 0,03815272 ! blastocyst formation GO:0001825 17 10 0,000 0,01844207 0,03811994 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01844207 0,03808722 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01844207 0,03805456 ! activation of innate immune response GO:0002218 12 10 0,000 0,01844207 0,03802195 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01844207 0,03798939 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01844207 0,0379569 ! response to nicotine GO:0035094 20 10 0,000 0,01844207 0,03792446 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01844207 0,03789207 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01844207 0,03785974 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01844207 0,03782746 ! localization within membrane GO:0051668 20 10 0,000 0,01844207 0,03779524 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0202678 0,04150155 ! respiratory burst GO:0045730 17 11 0,000 0,0202678 0,04146626 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0202678 0,04143103 ! neuron fate specification GO:0048665 17 11 0,000 0,0202678 0,04139586 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0202678 0,04136075 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0202678 0,04132569 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0202678 0,0412907 ! thyroid gland development GO:0030878 26 11 0,000 0,0202678 0,04125577 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,0202678 0,0412209 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0202678 0,04118608 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0202678 0,04115132 ! response to pain GO:0048265 24 11 0,000 0,0202678 0,04111663 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0202678 0,04108199 ! T cell proliferation GO:0042098 26 11 0,000 0,0202678 0,04104741 ! blood vessel remodeling GO:0001974 29 11 0,000 0,0202678 0,04101288 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0202678 0,04097842 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,0202678 0,04094401 ! bone resorption GO:0045453 16 11 0,000 0,0202678 0,04090966 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,0202678 0,04087537 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0202678 0,04084114 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0202678 0,04080696 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0202678 0,04077284 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0202678 0,04073878 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0202678 0,04070477 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0202678 0,04067082 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0202678 0,04063693 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0202678 0,0406031 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0202678 0,04056932 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,0202678 0,04053559 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0202678 0,04050193 ! UV protection GO:0009650 19 11 0,000 0,0202678 0,04046831 ! adult heart development GO:0007512 14 11 0,000 0,0202678 0,04043476 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0202678 0,04040126 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0202678 0,04036781 ! temperature homeostasis GO:0001659 17 11 0,000 0,0202678 0,04033442 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0202678 0,04030109 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0202678 0,04026781 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0202678 0,04023459 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0202678 0,04020142 ! regulation of organ growth GO:0046620 13 11 0,000 0,0202678 0,0401683 ! pigment granule localization GO:0051875 20 11 0,000 0,0202678 0,04013524 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0202678 0,04010224 ! vasoconstriction GO:0042310 18 11 0,000 0,0202678 0,04006928 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0202678 0,04003639 ! embryonic axis specification GO:0000578 18 11 0,000 0,0202678 0,04000354 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0202678 0,03997075 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0202678 0,03993802 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0202678 0,03990533 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0202678 0,03987271 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0202678 0,03984013 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0202678 0,03980761 ! zymogen activation GO:0031638 15 11 0,000 0,0202678 0,03977514 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0202678 0,03974272 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0202678 0,03971036 ! nucleosome positioning GO:0016584 15 11 0,000 0,0202678 0,03967805 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0202678 0,03964579 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0202678 0,03961358 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0202678 0,03958143 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,0202678 0,03954933 ! acid secretion GO:0046717 18 11 0,000 0,0202678 0,03951728 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0202678 0,03948528 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0202678 0,03945333 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0202678 0,03942144 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0202678 0,0393896 ! oocyte differentiation GO:0009994 18 11 0,000 0,0202678 0,0393578 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0202678 0,03932606 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0202678 0,03929437 ! cholesterol efflux GO:0033344 19 11 0,000 0,0202678 0,03926274 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0202678 0,03923115 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0202678 0,03919961 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0202678 0,03916813 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,0202678 0,03913669 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0202678 0,03910531 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0202678 0,03907397 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0202678 0,03904269 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0202678 0,03901146 ! defense response to fungus GO:0050832 13 11 0,000 0,0202678 0,03898027 ! developmental induction GO:0031128 19 11 0,000 0,0202678 0,03894914 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0202678 0,03891805 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0202678 0,03888702 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0202678 0,03885603 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0202678 0,03882509 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0202678 0,03879421 ! nucleus localization GO:0051647 19 11 0,000 0,0202678 0,03876337 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0202678 0,03873258 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02209019 0,04218175 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02209019 0,04214829 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02209019 0,0421149 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02209019 0,04208155 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02209019 0,04204826 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02209019 0,04201502 ! cartilage condensation GO:0001502 20 12 0,000 0,02209019 0,04198183 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02209019 0,0419487 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02209019 0,04191561 ! protein complex disassembly GO:0043241 27 12 0,000 0,02209019 0,04188258 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02209019 0,04184961 ! hippocampus development GO:0021766 26 12 0,000 0,02209019 0,04181668 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02209019 0,0417838 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02209019 0,04175098 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02209019 0,04171821 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02209019 0,04168549 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02209019 0,04165282 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02209019 0,0416202 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02209019 0,04158764 ! drug transport GO:0015893 16 12 0,000 0,02209019 0,04155512 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02209019 0,04152266 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02209019 0,04149024 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02209019 0,04145788 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02209019 0,04142556 ! focal adhesion formation GO:0048041 35 12 0,000 0,02209019 0,0413933 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02209019 0,04136109 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02209019 0,04132893 ! forebrain cell migration GO:0021885 21 12 0,000 0,02209019 0,04129681 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02209019 0,04126475 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02209019 0,04123274 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02209019 0,04120078 ! entry into host cell GO:0030260 32 12 0,000 0,02209019 0,04116886 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02209019 0,041137 ! monoamine transport GO:0015844 18 12 0,000 0,02209019 0,04110518 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02209019 0,04107342 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02209019 0,0410417 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02209019 0,04101003 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02209019 0,04097841 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02209019 0,04094684 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02209019 0,04091532 ! protein homotetramerization GO:0051289 21 12 0,000 0,02209019 0,04088385 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02209019 0,04085242 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02209019 0,04082104 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02209019 0,04078972 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02209019 0,04075844 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02209019 0,0407272 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02209019 0,04069602 ! cranial nerve development GO:0021545 20 12 0,000 0,02209019 0,04066488 ! fucose catabolic process GO:0019317 22 12 0,000 0,02209019 0,04063379 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02209019 0,04060275 ! histone acetylation GO:0016573 26 12 0,000 0,02209019 0,04057176 ! histone methylation GO:0016571 26 12 0,000 0,02209019 0,04054081 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02209019 0,04050991 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02209019 0,04047906 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02209019 0,04044825 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02209019 0,04041749 ! T cell homeostasis GO:0043029 25 12 0,000 0,02209019 0,04038678 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02209019 0,04035611 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02209019 0,04032549 ! spleen development GO:0048536 22 12 0,000 0,02209019 0,04029492 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02209019 0,04026439 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02209019 0,04023391 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02209019 0,04020348 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02209019 0,04017309 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02209019 0,04014275 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02209019 0,04011245 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02209019 0,0400822 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02209019 0,040052 ! response to cold GO:0009409 17 12 0,000 0,02209019 0,04002184 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02209019 0,03999172 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02209019 0,03996165 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02390926 0,04321989 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02390926 0,04318744 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02390926 0,04315504 ! peroxisomal transport GO:0043574 24 13 0,000 0,02390926 0,04312269 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02390926 0,04309039 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02390926 0,04305814 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02390926 0,04302593 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02390926 0,04299377 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02390926 0,04296167 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02390926 0,0429296 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02390926 0,04289759 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02390926 0,04286563 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02390926 0,04283371 ! methionine metabolic process GO:0006555 27 13 0,000 0,02390926 0,04280184 ! plasma membrane organization GO:0007009 24 13 0,000 0,02390926 0,04277001 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02390926 0,04273824 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02390926 0,04270651 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02390926 0,04267483 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02390926 0,04264319 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02390926 0,04261161 ! response to X-ray GO:0010165 25 13 0,000 0,02390926 0,04258007 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02390926 0,04254857 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02390926 0,04251712 ! exocrine system development GO:0035272 32 13 0,000 0,02390926 0,04248572 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02390926 0,04245437 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02390926 0,04242306 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02390926 0,0423918 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02390926 0,04236058 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02390926 0,04232941 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02390926 0,04229829 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02390926 0,04226721 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02390926 0,04223617 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02390926 0,04220519 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02390926 0,04217424 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02390926 0,04214335 ! ribosome assembly GO:0042255 17 13 0,000 0,02390926 0,0421125 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02390926 0,04208169 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02390926 0,04205093 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02390926 0,04202021 ! chromatin silencing GO:0006342 26 13 0,000 0,02390926 0,04198954 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02390926 0,04195891 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02390926 0,04192833 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02390926 0,04189779 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02390926 0,0418673 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02390926 0,04183685 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02390926 0,04180645 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02390926 0,04177609 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02390926 0,04174577 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02390926 0,0417155 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02390926 0,04168527 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02390926 0,04165508 ! embryonic placenta development GO:0001892 23 13 0,000 0,02390926 0,04162494 ! insulin secretion GO:0030073 23 13 0,000 0,02390926 0,04159484 ! actin filament polymerization GO:0030041 24 13 0,000 0,02390926 0,04156479 ! acrosome reaction GO:0007340 18 13 0,000 0,02390926 0,04153478 ! rRNA transcription GO:0009303 25 14 0,000 0,025725 0,04465681 ! lactation GO:0007595 26 14 0,000 0,025725 0,04462462 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,025725 0,04459247 ! reproductive cellular process GO:0048610 20 14 0,000 0,025725 0,04456036 ! tRNA modification GO:0006400 20 14 0,000 0,025725 0,04452831 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,025725 0,04449629 ! regulation of S phase GO:0033261 23 14 0,000 0,025725 0,04446433 ! water transport GO:0006833 21 14 0,000 0,025725 0,04443241 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,025725 0,04440053 ! non-recombinational repair GO:0000726 25 14 0,000 0,025725 0,04436871 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,025725 0,04433692 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,025725 0,04430519 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,025725 0,04427349 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,025725 0,04424185 ! RNA polyadenylation GO:0043631 30 14 0,000 0,025725 0,04421025 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,025725 0,04417869 ! palate development GO:0060021 31 14 0,000 0,025725 0,04414718 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,025725 0,04411571 ! regulated secretory pathway GO:0045055 23 14 0,000 0,025725 0,04408429 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,025725 0,04405291 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,025725 0,04402158 ! arginine metabolic process GO:0006525 17 14 0,000 0,025725 0,04399029 ! regulation of heart rate GO:0002027 24 14 0,000 0,025725 0,04395905 ! organic alcohol transport GO:0015850 29 14 0,000 0,025725 0,04392785 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,025725 0,0438967 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,025725 0,04386559 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,025725 0,04383452 ! neutral amino acid transport GO:0015804 26 14 0,000 0,025725 0,0438035 ! L-amino acid transport GO:0015807 30 14 0,000 0,025725 0,04377252 ! bone mineralization GO:0030282 17 14 0,000 0,025725 0,04374159 ! stem cell development GO:0048864 43 14 0,000 0,025725 0,04371069 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,025725 0,04367985 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,025725 0,04364904 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,025725 0,04361828 ! cerebellum development GO:0021549 21 14 0,000 0,025725 0,04358757 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,025725 0,04355689 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,025725 0,04352626 ! response to gamma radiation GO:0010332 28 14 0,000 0,025725 0,04349567 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,025725 0,04346513 ! cofactor transport GO:0051181 26 14 0,000 0,025725 0,04343463 ! NADP metabolic process GO:0006739 24 14 0,000 0,025725 0,04340417 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,025725 0,04337375 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,025725 0,04334338 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,025725 0,04331305 ! oxygen transport GO:0015671 21 14 0,000 0,025725 0,04328276 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,025725 0,04325251 ! male genitalia development GO:0030539 24 14 0,000 0,025725 0,04322231 ! regulation of axon extension GO:0030516 37 14 0,000 0,025725 0,04319215 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,025725 0,04316203 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,025725 0,04313195 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02753742 0,0461386 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02753742 0,0461065 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02753742 0,04607443 ! superoxide anion generation GO:0042554 20 15 0,000 0,02753742 0,04604242 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02753742 0,04601044 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02753742 0,04597851 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02753742 0,04594663 ! copper ion transport GO:0006825 20 15 0,000 0,02753742 0,04591479 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02753742 0,04588299 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02753742 0,04585124 ! sulfate transport GO:0008272 23 15 0,000 0,02753742 0,04581953 ! response to cAMP GO:0051591 22 15 0,000 0,02753742 0,04578786 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02753742 0,04575624 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02753742 0,04572466 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02753742 0,04569313 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02753742 0,04566164 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! response to hexose stimulus GO:0009746 22 15 0,000 0,02753742 0,04563019 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02753742 0,04559879 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02753742 0,04556743 ! pituitary gland development GO:0021983 29 15 0,000 0,02753742 0,04553611 ! vesicle coating GO:0006901 33 15 0,000 0,02753742 0,04550483 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02753742 0,0454736 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02753742 0,04544241 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02753742 0,04541127 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02753742 0,04538016 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02753742 0,0453491 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02753742 0,04531808 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02753742 0,04528711 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02753742 0,04525617 ! histone deacetylation GO:0016575 20 15 0,000 0,02753742 0,04522528 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02753742 0,04519443 ! tissue regeneration GO:0042246 26 15 0,000 0,02753742 0,04516362 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02753742 0,04513286 ! water homeostasis GO:0030104 27 15 0,000 0,02753742 0,04510213 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02753742 0,04507145 ! muscle maintenance GO:0046716 26 15 0,000 0,02753742 0,04504081 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02753742 0,04501021 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02753742 0,04497966 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02753742 0,04494914 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02753742 0,04491867 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02753742 0,04488824 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02753742 0,04485784 ! detection of bacterium GO:0016045 18 15 0,000 0,02753742 0,04482749 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02753742 0,04479718 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02753742 0,04476692 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02753742 0,04473669 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02753742 0,0447065 ! peptide hormone processing GO:0016486 23 15 0,000 0,02753742 0,04467636 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02934653 0,04757935 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02934653 0,04754731 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02934653 0,04751532 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02934653 0,04748336 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02934653 0,04745145 ! bone remodeling GO:0046849 27 16 0,000 0,02934653 0,04741958 ! filopodium assembly GO:0046847 32 16 0,000 0,02934653 0,04738776 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02934653 0,04735598 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02934653 0,04732424 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02934653 0,04729254 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02934653 0,04726088 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02934653 0,04722927 ! startle response GO:0001964 28 16 0,000 0,02934653 0,0471977 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02934653 0,04716617 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02934653 0,04713469 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02934653 0,04710324 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02934653 0,04707184 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02934653 0,04704048 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02934653 0,04700916 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02934653 0,04697788 ! response to osmotic stress GO:0006970 25 16 0,000 0,02934653 0,04694665 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02934653 0,04691546 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02934653 0,0468843 ! fructose metabolic process GO:0006000 25 16 0,000 0,02934653 0,04685319 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02934653 0,04682212 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02934653 0,04679109 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02934653 0,04676011 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02934653 0,04672916 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02934653 0,04669825 ! axon cargo transport GO:0008088 43 16 0,000 0,02934653 0,04666739 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02934653 0,04663657 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02934653 0,04660578 ! DNA replication initiation GO:0006270 27 16 0,000 0,02934653 0,04657504 ! neuron recognition GO:0008038 35 16 0,000 0,02934653 0,04654434 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02934653 0,04651368 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02934653 0,04648306 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02934653 0,04645247 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02934653 0,04642193 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02934653 0,04639143 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02934653 0,04636097 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02934653 0,04633055 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02934653 0,04630017 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02934653 0,04626983 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02934653 0,04623953 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02934653 0,04620927 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02934653 0,04617905 ! defense response to virus GO:0051607 37 16 0,000 0,02934653 0,04614886 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03115234 0,04895659 ! metencephalon development GO:0022037 30 17 0,000 0,03115234 0,04892463 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03115234 0,04889272 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03115234 0,04886084 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03115234 0,04882901 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03115234 0,04879722 ! endothelial cell migration GO:0043542 28 17 0,000 0,03115234 0,04876547 ! inositol metabolic process GO:0006020 28 17 0,000 0,03115234 0,04873377 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03115234 0,0487021 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03115234 0,04867048 ! glial cell development GO:0021782 27 17 0,000 0,03115234 0,04863889 ! limbic system development GO:0021761 36 17 0,000 0,03115234 0,04860735 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03115234 0,04857585 ! adult walking behavior GO:0007628 33 17 0,000 0,03115234 0,04854439 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03115234 0,04851297 ! heart looping GO:0001947 30 17 0,000 0,03115234 0,04848159 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03115234 0,04845025 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03115234 0,04841895 ! myoblast differentiation GO:0045445 45 17 0,000 0,03115234 0,04838769 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03115234 0,04835647 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03115234 0,04832529 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03115234 0,04829416 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03115234 0,04826306 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03115234 0,048232 ! glycine metabolic process GO:0006544 28 17 0,000 0,03115234 0,04820099 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03115234 0,04817001 ! NAD metabolic process GO:0019674 29 17 0,000 0,03115234 0,04813907 ! membrane budding GO:0006900 37 17 0,000 0,03115234 0,04810817 ! DNA integration GO:0015074 29 17 0,000 0,03115234 0,04807731 ! regulation of protein binding GO:0043393 33 17 0,000 0,03115234 0,0480465 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03115234 0,04801572 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03115234 0,04798498 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03115234 0,04795428 ! genitalia development GO:0048806 30 17 0,000 0,03115234 0,04792361 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03115234 0,04789299 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03115234 0,04786241 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03115234 0,04783186 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03115234 0,04780136 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03115234 0,04777089 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03115234 0,04774047 ! steroid catabolic process GO:0006706 31 17 0,000 0,03115234 0,04771008 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03115234 0,04767973 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03115234 0,04764942 ! gas transport GO:0015669 25 17 0,000 0,03115234 0,04761914 ! organic cation transport GO:0015695 31 17 0,000 0,03115234 0,04758891 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03115234 0,04755871 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03115234 0,04752856 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03115234 0,04749844 ! microspike assembly GO:0030035 36 17 0,000 0,03115234 0,04746835 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03115234 0,04743831 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03115234 0,04740831 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03295485 0,0501197 ! neuron maturation GO:0042551 42 18 0,000 0,03295485 0,05008804 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03295485 0,05005642 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03295485 0,05002484 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03295485 0,04999329 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03295485 0,04996179 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03295485 0,04993033 ! memory GO:0007613 31 18 0,000 0,03295485 0,04989891 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03295485 0,04986753 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03295485 0,04983618 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03295485 0,04980488 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03295485 0,04977361 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03295485 0,04974239 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03295485 0,0497112 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03295485 0,04968005 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03295485 0,04964894 ! response to retinoic acid GO:0032526 26 18 0,000 0,03295485 0,04961788 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03295485 0,04958684 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03295485 0,04955585 ! response to fungus GO:0009620 21 18 0,000 0,03295485 0,0495249 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03295485 0,04949399 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03295485 0,04946311 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03295485 0,04943227 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03295485 0,04940147 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03295485 0,04937071 ! vitamin transport GO:0051180 27 18 0,000 0,03295485 0,04933999 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03295485 0,04930931 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03295485 0,04927866 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03295485 0,04924805 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03295485 0,04921748 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03295485 0,04918695 ! nerve development GO:0021675 28 18 0,000 0,03295485 0,04915646 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03295485 0,049126 ! protein secretion GO:0009306 39 19 0,000 0,03475406 0,05177602 ! positive regulation of translation GO:0045727 30 19 0,000 0,03475406 0,05174398 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03475406 0,05171198 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03475406 0,05168002 ! skin development GO:0043588 36 19 0,000 0,03475406 0,0516481 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03475406 0,05161622 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03475406 0,05158438 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03475406 0,05155257 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03475406 0,05152081 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03475406 0,05148908 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03475406 0,0514574 ! cerebral cortex development GO:0021987 36 19 0,000 0,03475406 0,05142575 ! pigmentation during development GO:0048066 41 19 0,000 0,03475406 0,05139414 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03475406 0,05136258 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03475406 0,05133105 ! heme metabolic process GO:0042168 36 19 0,000 0,03475406 0,05129955 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03475406 0,0512681 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03475406 0,05123669 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03475406 0,05120531 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03475406 0,05117397 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03475406 0,05114267 ! peptide cross-linking GO:0018149 37 19 0,000 0,03475406 0,05111141 ! protein export from nucleus GO:0006611 36 19 0,000 0,03475406 0,05108019 ! heart process GO:0003015 30 19 0,000 0,03475406 0,05104901 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03475406 0,05101786 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03475406 0,05098675 ! cellular pigmentation GO:0033059 36 19 0,000 0,03475406 0,05095568 ! G1 phase GO:0051318 40 19 0,000 0,03475406 0,05092465 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03475406 0,05089365 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03475406 0,0508627 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03475406 0,05083178 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03475406 0,05080089 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03475406 0,05077005 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03475406 0,05073924 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03475406 0,05070847 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03475406 0,05067774 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03475406 0,05064705 ! cilium assembly GO:0042384 37 19 0,000 0,03475406 0,05061639 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03475406 0,05058577 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03654999 0,05316764 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03654999 0,05313551 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03654999 0,05310342 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03654999 0,05307138 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03654999 0,05303937 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03654999 0,0530074 ! response to vitamin GO:0033273 31 20 0,000 0,03654999 0,05297546 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03654999 0,05294357 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03654999 0,05291171 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03654999 0,0528799 ! response to alkaloid GO:0043279 38 20 0,000 0,03654999 0,05284812 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03654999 0,05281638 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03654999 0,05278468 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03654999 0,05275301 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03654999 0,05272138 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03654999 0,0526898 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03654999 0,05265825 ! body fluid secretion GO:0007589 31 20 0,000 0,03654999 0,05262673 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03654999 0,05259526 ! peptide secretion GO:0002790 35 20 0,000 0,03654999 0,05256382 ! stem cell differentiation GO:0048863 53 20 0,000 0,03654999 0,05253242 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03654999 0,05250106 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03654999 0,05246973 ! sensory perception of pain GO:0019233 30 20 0,000 0,03654999 0,05243844 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03654999 0,05240719 ! diencephalon development GO:0021536 34 20 0,000 0,03654999 0,05237598 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03654999 0,0523448 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03654999 0,05231366 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03654999 0,05228256 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03654999 0,0522515 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03654999 0,05222047 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03654999 0,05218948 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03654999 0,05215852 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03654999 0,05212761 ! regulation of glucose import GO:0046324 29 20 0,000 0,03654999 0,05209672 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03654999 0,05206588 ! actin filament-based movement GO:0030048 43 20 0,000 0,03654999 0,05203507 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03654999 0,0520043 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03654999 0,05197356 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03654999 0,05194286 ! negative regulation of translation GO:0017148 29 20 0,000 0,03654999 0,0519122 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03654999 0,05188158 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03654999 0,05185098 ! regulation of cell killing GO:0031341 42 21 0,000 0,03834263 0,05436203 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03834263 0,05433002 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03834263 0,05429804 ! hormone secretion GO:0046879 38 21 0,000 0,03834263 0,0542661 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03834263 0,0542342 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03834263 0,05420233 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03834263 0,05417051 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03834263 0,05413872 ! axis specification GO:0009798 38 21 0,000 0,03834263 0,05410696 ! ovarian follicle development GO:0001541 35 21 0,000 0,03834263 0,05407525 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03834263 0,05404357 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03834263 0,05401193 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03834263 0,05398032 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03834263 0,05394875 ! cell aging GO:0007569 44 21 0,000 0,03834263 0,05391722 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03834263 0,05388573 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03834263 0,05385427 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03834263 0,05382285 ! vasodilation GO:0042311 39 21 0,000 0,03834263 0,05379147 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03834263 0,05376012 ! oogenesis GO:0048477 36 21 0,000 0,03834263 0,05372881 ! DNA modification GO:0006304 34 21 0,000 0,03834263 0,05369754 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03834263 0,0536663 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03834263 0,0536351 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03834263 0,05360393 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03834263 0,05357281 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03834263 0,05354171 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03834263 0,05351066 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03834263 0,05347964 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03834263 0,05344865 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03834263 0,0534177 ! collagen catabolic process GO:0030574 28 21 0,000 0,03834263 0,05338679 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03834263 0,05335591 ! gut development GO:0048565 39 21 0,000 0,03834263 0,05332507 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,040132 0,05578139 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,040132 0,05574919 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,040132 0,05571702 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,040132 0,05568488 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,040132 0,05565279 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,040132 0,05562073 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,040132 0,05558871 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,040132 0,05555673 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,040132 0,05552478 ! regeneration GO:0031099 41 22 0,000 0,040132 0,05549287 ! keratinization GO:0031424 28 22 0,000 0,040132 0,05546099 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,040132 0,05542916 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,040132 0,05539735 ! sensory perception of taste GO:0050909 28 22 0,000 0,040132 0,05536559 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,040132 0,05533386 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,040132 0,05530217 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,040132 0,05527052 ! vacuolar transport GO:0007034 36 22 0,000 0,040132 0,0552389 ! lysosome organization GO:0007040 41 22 0,000 0,040132 0,05520731 ! central nervous system neuron development GO:0021954 46 22 0,000 0,040132 0,05517577 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,040132 0,05514425 ! fucose metabolic process GO:0006004 39 22 0,000 0,040132 0,05511278 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,040132 0,05508134 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,040132 0,05504994 ! ureteric bud development GO:0001657 43 22 0,000 0,040132 0,05501857 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,040132 0,05498724 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,040132 0,05495594 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,040132 0,05492468 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,040132 0,05489346 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,040132 0,05486227 ! sarcomere organization GO:0045214 30 22 0,000 0,040132 0,05483111 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,040132 0,05479999 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,040132 0,05476891 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,040132 0,05473786 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,040132 0,05470685 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,040132 0,05467587 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0419181 0,05707693 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,0419181 0,05704465 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,0419181 0,0570124 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0419181 0,05698019 ! gluconeogenesis GO:0006094 33 23 0,000 0,0419181 0,05694802 ! viral genome replication GO:0019079 41 23 0,000 0,0419181 0,05691588 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0419181 0,05688378 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0419181 0,05685171 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0419181 0,05681968 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0419181 0,05678769 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0419181 0,05675573 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0419181 0,05672381 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0419181 0,05669193 ! response to ethanol GO:0045471 46 23 0,000 0,0419181 0,05666008 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0419181 0,05662827 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0419181 0,05659649 ! peroxisome organization GO:0007031 37 23 0,000 0,0419181 0,05656475 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0419181 0,05653304 ! vesicle targeting GO:0006903 43 23 0,000 0,0419181 0,05650137 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0419181 0,05646973 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,0419181 0,05643813 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0419181 0,05640657 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0419181 0,05637504 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0419181 0,05634354 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0419181 0,05631208 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0419181 0,05628066 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0419181 0,05624927 ! fatty acid transport GO:0015908 44 23 0,000 0,0419181 0,05621792 ! platelet activation GO:0030168 37 23 0,000 0,0419181 0,0561866 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0419181 0,05615531 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0419181 0,05612406 ! hormone transport GO:0009914 40 23 0,000 0,0419181 0,05609285 ! cell-cell recognition GO:0009988 25 23 0,000 0,0419181 0,05606167 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0419181 0,05603052 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0419181 0,05599941 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0419181 0,05596834 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0419181 0,05593729 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04370093 0,05828406 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,04370093 0,05825177 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04370093 0,05821951 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04370093 0,05818729 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04370093 0,05815511 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04370093 0,05812296 ! spinal cord development GO:0021510 47 24 0,000 0,04370093 0,05809085 ! vacuole organization GO:0007033 43 24 0,000 0,04370093 0,05805877 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04370093 0,05802673 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04370093 0,05799473 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04370093 0,05796276 ! regulation of behavior GO:0050795 43 24 0,000 0,04370093 0,05793082 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04370093 0,05789892 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04370093 0,05786705 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04370093 0,05783522 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,04370093 0,05780343 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04370093 0,05777167 ! pallium development GO:0021543 49 24 0,000 0,04370093 0,05773994 ! pentose metabolic process GO:0019321 35 24 0,000 0,04370093 0,05770825 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,04370093 0,0576766 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04370093 0,05764498 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04370093 0,05761339 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04370093 0,05758184 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04370093 0,05755032 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04370093 0,05751884 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04370093 0,05748739 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04370093 0,05745598 ! regulation of amine transport GO:0051952 40 24 0,000 0,04370093 0,0574246 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0454805 0,0597304 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,0454805 0,05969781 ! myelination GO:0042552 45 25 0,000 0,0454805 0,05966526 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0454805 0,05963275 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0454805 0,05960027 ! phototransduction GO:0007602 33 25 0,000 0,0454805 0,05956783 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0454805 0,05953542 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,0454805 0,05950304 ! sperm motility GO:0030317 31 25 0,000 0,0454805 0,0594707 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,0454805 0,0594384 ! chromosome condensation GO:0030261 45 25 0,000 0,0454805 0,05940613 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0454805 0,0593739 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,0454805 0,0593417 ! neural crest cell development GO:0014032 54 25 0,000 0,0454805 0,05930954 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0454805 0,05927741 ! negative regulation of cell development GO:0010721 73 25 0,000 0,0454805 0,05924531 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0454805 0,05921325 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0454805 0,05918123 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0454805 0,05914924 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0454805 0,05911729 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0454805 0,05908536 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,0454805 0,05905348 ! immunoglobulin production GO:0002377 55 25 0,000 0,0454805 0,05902163 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0454805 0,05898981 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0454805 0,05895803 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0454805 0,05892628 ! telomere organization GO:0032200 43 25 0,000 0,0454805 0,05889456 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0454805 0,05886288 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0454805 0,05883123 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04725683 0,06109615 ! embryonic pattern specification GO:0009880 44 26 0,000 0,04725683 0,06106333 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,04725683 0,06103056 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,04725683 0,06099781 ! initiation of viral infection GO:0019059 57 26 0,000 0,04725683 0,06096511 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04725683 0,06093244 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04725683 0,0608998 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04725683 0,0608672 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04725683 0,06083463 ! molting cycle process GO:0022404 50 26 0,000 0,04725683 0,0608021 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04725683 0,0607696 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04725683 0,06073714 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04725683 0,06070471 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,04725683 0,06067232 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,04725683 0,06063996 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,04725683 0,06060764 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,04725683 0,06057535 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04725683 0,06054309 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,04725683 0,06051087 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,04725683 0,06047868 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04725683 0,06044653 ! blastocyst development GO:0001824 49 26 0,000 0,04725683 0,06041441 ! leukocyte proliferation GO:0070661 52 26 0,000 0,04725683 0,06038233 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04725683 0,06035028 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04725683 0,06031826 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,0490299 0,06254822 ! neuron fate commitment GO:0048663 48 27 0,000 0,0490299 0,06251507 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0490299 0,06248196 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0490299 0,06244889 ! iron ion transport GO:0006826 59 27 0,000 0,0490299 0,06241584 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,0490299 0,06238284 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0490299 0,06234987 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0490299 0,06231693 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0490299 0,06228403 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0490299 0,06225116 ! fat cell differentiation GO:0045444 50 27 0,000 0,0490299 0,06221833 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0490299 0,06218553 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0490299 0,06215276 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0490299 0,06212003 ! autophagy GO:0006914 41 27 0,000 0,0490299 0,06208734 ! male gonad development GO:0008584 44 27 0,000 0,0490299 0,06205468 ! response to toxin GO:0009636 47 27 0,000 0,0490299 0,06202205 ! primary neural tube formation GO:0014020 51 27 0,000 0,0490299 0,06198946 ! base-excision repair GO:0006284 41 27 0,000 0,0490299 0,0619569 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0490299 0,06192438 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0490299 0,06189189 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0490299 0,06185944 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0490299 0,06182702 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0490299 0,06179463 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0490299 0,06176228 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0490299 0,06172996 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05079974 0,06392477 ! circadian rhythm GO:0007623 50 28 0,000 0,05079974 0,06389136 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05079974 0,06385798 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05079974 0,06382463 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05079974 0,06379132 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05079974 0,06375804 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,05079974 0,0637248 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05079974 0,06369159 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05079974 0,06365842 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05079974 0,06362528 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05079974 0,06359218 ! synaptogenesis GO:0007416 42 28 0,000 0,05079974 0,06355911 ! lipid oxidation GO:0034440 43 28 0,000 0,05079974 0,06352608 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05079974 0,06349307 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05079974 0,06346011 ! translational initiation GO:0006413 65 29 0,000 0,05256634 0,0656329 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,05256634 0,06559886 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,05256634 0,06556486 ! regulation of pH GO:0006885 43 29 0,000 0,05256634 0,06553088 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,05256634 0,06549695 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,05256634 0,06546305 ! catechol metabolic process GO:0009712 54 29 0,000 0,05256634 0,06542918 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,05256634 0,06539535 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,05256634 0,06536155 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,05256634 0,06532779 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,05256634 0,06529407 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,05256634 0,06526038 ! cell fate determination GO:0001709 60 29 0,000 0,05256634 0,06522672 ! detection of light stimulus GO:0009583 38 29 0,000 0,05256634 0,0651931 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,05256634 0,06515951 ! tissue homeostasis GO:0001894 48 29 0,000 0,05256634 0,06512596 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,05432971 0,067276 ! zinc ion transport GO:0006829 45 30 0,000 0,05432971 0,0672414 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,05432971 0,06720683 ! cell junction assembly GO:0034329 78 30 0,000 0,05432971 0,06717229 ! regulation of innate immune response GO:0045088 51 30 0,000 0,05432971 0,06713779 ! acute-phase response GO:0006953 49 30 0,000 0,05432971 0,06710332 ! myofibril assembly GO:0030239 47 30 0,000 0,05432971 0,06706889 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,05432971 0,0670345 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,05432971 0,06700014 ! phospholipid transport GO:0015914 51 30 0,000 0,05432971 0,06696582 ! ensheathment of neurons GO:0007272 57 30 0,000 0,05432971 0,06693153 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,05432971 0,06689728 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,05432971 0,06686306 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,05432971 0,06682887 ! eye morphogenesis GO:0048592 60 30 0,000 0,05432971 0,06679472 ! regulation of B cell activation GO:0050864 50 30 0,000 0,05432971 0,06676061 ! response to heat GO:0009408 50 30 0,000 0,05432971 0,06672653 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05608985 0,06885316 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05608985 0,06881805 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05608985 0,06878297 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05608985 0,06874793 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05608985 0,06871293 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05608985 0,06867796 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05608985 0,06864303 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05608985 0,06860813 ! ovulation cycle process GO:0022602 49 31 0,000 0,05608985 0,06857327 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05608985 0,06853844 ! peptide transport GO:0015833 55 31 0,000 0,05608985 0,06850365 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05608985 0,06846889 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05608985 0,06843417 ! mesoderm formation GO:0001707 69 31 0,000 0,05608985 0,06839949 ! natural killer cell activation GO:0030101 45 31 0,000 0,05608985 0,06836484 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,05608985 0,06833022 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05608985 0,06829564 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05608985 0,0682611 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05608985 0,06822659 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,05784678 0,07032813 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,05784678 0,07029261 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,05784678 0,07025712 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,05784678 0,07022168 ! spliceosome assembly GO:0000245 67 32 0,000 0,05784678 0,07018626 ! spindle organization GO:0007051 46 32 0,000 0,05784678 0,07015089 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,05784678 0,07011555 ! metanephros development GO:0001656 74 32 0,000 0,05784678 0,07008024 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,05784678 0,07004497 ! response to ionizing radiation GO:0010212 65 32 0,000 0,05784678 0,07000974 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,05784678 0,06997454 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,05784678 0,06993938 ! muscle cell development GO:0055001 49 32 0,000 0,05784678 0,06990425 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,05784678 0,06986916 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,05784678 0,0698341 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,05784678 0,06979908 ! ovulation cycle GO:0042698 51 32 0,000 0,05784678 0,06976409 ! peripheral nervous system development GO:0007422 64 32 0,000 0,05784678 0,06972914 ! BMP signaling pathway GO:0030509 64 32 0,000 0,05784678 0,06969422 ! hindbrain development GO:0030902 61 32 0,000 0,05784678 0,06965934 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,05784678 0,06962449 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,05784678 0,06958968 ! gene silencing GO:0016458 65 32 0,000 0,05784678 0,0695549 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0596005 0,07162777 ! post-embryonic development GO:0009791 69 33 0,000 0,0596005 0,07159201 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0596005 0,07155629 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0596005 0,0715206 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0596005 0,07148495 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0596005 0,07144933 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0596005 0,07141375 ! cell fate specification GO:0001708 52 33 0,000 0,0596005 0,0713782 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0596005 0,07134269 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0596005 0,07130721 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0596005 0,07127177 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0596005 0,07123637 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,06135101 0,07329222 ! glial cell differentiation GO:0010001 63 34 0,000 0,06135101 0,07325585 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,06135101 0,07321951 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,06135101 0,07318321 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,06135101 0,07314694 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,06135101 0,07311071 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,06135101 0,07307452 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,06135101 0,07303836 ! mismatch repair GO:0006298 46 34 0,000 0,06135101 0,07300224 ! spermatid development GO:0007286 63 34 0,000 0,06135101 0,07296616 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,06135101 0,07293011 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,06135101 0,07289409 ! placenta development GO:0001890 53 34 0,000 0,06135101 0,07285811 ! regulation of muscle development GO:0048634 70 35 0,000 0,06309832 0,07489618 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,06309832 0,07485925 ! negative regulation of secretion GO:0051048 63 35 0,000 0,06309832 0,07482236 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,06309832 0,0747855 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,06309832 0,07474868 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,06309832 0,07471189 ! odontogenesis GO:0042476 66 35 0,000 0,06309832 0,07467514 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,06309832 0,07463843 ! female gonad development GO:0008585 58 35 0,000 0,06309832 0,07460175 ! telencephalon development GO:0021537 68 35 0,000 0,06309832 0,07456511 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,06309832 0,0745285 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,06309832 0,07449193 ! cytokine production GO:0001816 59 35 0,000 0,06309832 0,0744554 ! neural tube formation GO:0001841 67 35 0,000 0,06309832 0,0744189 ! vesicle localization GO:0051648 64 35 0,000 0,06309832 0,07438244 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,06484244 0,07640103 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,06484244 0,07636363 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,06484244 0,07632627 ! cell junction organization GO:0034330 86 36 0,000 0,06484244 0,07628895 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,06484244 0,07625166 ! positive regulation of cell development GO:0010720 80 36 0,000 0,06484244 0,07621441 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,06484244 0,0761772 ! regulation of proteolysis GO:0030162 72 36 0,000 0,06484244 0,07614002 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,06484244 0,07610288 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,06484244 0,07606578 ! aerobic respiration GO:0009060 55 36 0,000 0,06484244 0,07602871 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,06484244 0,07599167 ! embryonic organ development GO:0048568 57 36 0,000 0,06484244 0,07595468 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,06484244 0,07591772 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,06484244 0,07588079 ! RNA export from nucleus GO:0006405 56 37 0,000 0,06658336 0,0778802 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,06658336 0,07784236 ! meiosis I GO:0007127 65 37 0,000 0,06658336 0,07780455 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,06658336 0,07776678 ! sister chromatid segregation GO:0000819 58 37 0,000 0,06658336 0,07772905 ! actomyosin structure organization GO:0031032 62 37 0,000 0,06658336 0,07769136 ! organic anion transport GO:0015711 68 37 0,000 0,06658336 0,0776537 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,06658336 0,07761607 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,06658336 0,07757849 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,06658336 0,07754094 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,06658336 0,07750342 ! pigment metabolic process GO:0042440 80 37 0,000 0,06658336 0,07746595 ! spermatid differentiation GO:0048515 66 37 0,000 0,06658336 0,0774285 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,06832111 0,07941091 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,06832111 0,07937257 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,06832111 0,07933426 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,06832111 0,07929599 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,06832111 0,07925776 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,06832111 0,07921956 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,06832111 0,0791814 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,06832111 0,07914328 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,06832111 0,07910519 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,06832111 0,07906714 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,06832111 0,07902913 ! glucan metabolic process GO:0044042 62 38 0,000 0,06832111 0,07899115 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,07005567 0,08095771 ! ear morphogenesis GO:0042471 60 39 0,000 0,07005567 0,08091884 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,07005567 0,08088002 ! segmentation GO:0035282 67 39 0,000 0,07005567 0,08084122 ! ion transmembrane transport GO:0034220 66 39 0,000 0,07005567 0,08080247 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,07005567 0,08076375 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,07005567 0,08072507 ! RNA modification GO:0009451 57 39 0,000 0,07005567 0,08068643 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,07005567 0,08064782 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,07178707 0,08260148 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,07178707 0,08256199 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,07178707 0,08252255 ! feeding behavior GO:0007631 59 40 0,000 0,07178707 0,08248314 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,07178707 0,08244377 ! mesenchymal cell development GO:0014031 87 40 0,000 0,07178707 0,08240443 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 0,000 0,07178707 0,08236514 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,0735153 0,08430782 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,0735153 0,08426765 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,0735153 0,08422753 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,0735153 0,08418744 ! gliogenesis GO:0042063 88 41 0,000 0,0735153 0,08414739 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,0735153 0,08410737 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,0735153 0,0840674 ! T cell differentiation GO:0030217 81 41 0,000 0,0735153 0,08402746 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,0735153 0,08398756 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,0735153 0,0839477 ! female gamete generation GO:0007292 61 41 0,000 0,0735153 0,08390788 ! polyol metabolic process GO:0019751 66 41 0,000 0,0735153 0,08386809 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,0735153 0,08382834 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,07524037 0,08575477 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,07524037 0,08571417 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,07524037 0,0856736 ! regulation of tube size GO:0035150 71 42 0,000 0,07524037 0,08563307 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,07524037 0,08559259 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,07524037 0,08555214 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,07524037 0,08551172 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,07524037 0,08547135 ! neuron migration GO:0001764 79 42 0,000 0,07524037 0,08543101 ! regulation of protein secretion GO:0050708 71 42 0,000 0,07524037 0,08539072 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,07524037 0,08535046 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,07696228 0,0872626 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,07696228 0,0872215 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,07696228 0,08718043 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,07696228 0,08713941 ! glucose transport GO:0015758 65 43 0,000 0,07696228 0,08709842 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,07696228 0,08705747 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,07696228 0,08701656 ! neural tube development GO:0021915 77 43 0,000 0,07696228 0,08697569 ! striated muscle contraction GO:0006941 77 43 0,000 0,07696228 0,08693486 ! phagocytosis GO:0006909 90 43 0,000 0,07696228 0,08689406 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,07696228 0,0868533 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,07868104 0,08875133 ! hexose transport GO:0008645 67 44 0,000 0,07868104 0,08870974 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,07868104 0,08866819 ! male sex differentiation GO:0046661 76 44 0,000 0,07868104 0,08862668 ! biopolymer methylation GO:0043414 84 44 0,000 0,07868104 0,08858521 ! B cell differentiation GO:0030183 107 44 0,000 0,07868104 0,08854377 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,07868104 0,08850238 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,07868104 0,08846102 ! developmental growth GO:0048589 82 44 0,000 0,07868104 0,08841971 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,08039666 0,0903055 ! glycolysis GO:0006096 65 45 0,000 0,08039666 0,09026336 ! leukocyte migration GO:0050900 68 45 0,000 0,08039666 0,09022126 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,08039666 0,09017919 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,08039666 0,09013717 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,08039666 0,09009519 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,08039666 0,09005325 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,08039666 0,09001134 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,08039666 0,08996948 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,08039666 0,08992765 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,08039666 0,08988586 ! cell growth GO:0016049 84 45 0,000 0,08039666 0,08984411 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,08210915 0,09171523 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,08210915 0,09167267 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,08210915 0,09163015 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,08210915 0,09158767 ! pigmentation GO:0043473 100 46 0,000 0,08210915 0,09154523 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0838185 0,09340774 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,0838185 0,09336449 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0838185 0,09332129 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,0838185 0,09327812 ! JNK cascade GO:0007254 91 47 0,000 0,0838185 0,093235 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,0838185 0,09319192 ! methylation GO:0032259 90 47 0,000 0,0838185 0,09314887 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,08552472 0,09500114 ! mitochondrial transport GO:0006839 82 48 0,000 0,08552472 0,09495731 ! Notch signaling pathway GO:0007219 96 48 0,000 0,08552472 0,09491351 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,08552472 0,09486975 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,08552472 0,09482603 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,08552472 0,09478235 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,08552472 0,09473871 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,08552472 0,09469511 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,08552472 0,09465155 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,08722782 0,09649202 ! regulation of action potential GO:0001508 95 49 0,000 0,08722782 0,09644768 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,08722782 0,09640337 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,08722782 0,09635911 ! regulation of ion transport GO:0043269 77 49 0,000 0,08722782 0,09631489 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,08722782 0,09627071 ! peptide metabolic process GO:0006518 76 49 0,000 0,08722782 0,09622657 ! response to temperature stimulus GO:0009266 76 49 0,000 0,08722782 0,09618247 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,08722782 0,09613841 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,08722782 0,09609439 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,08722782 0,09605041 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,08722782 0,09600647 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,08892781 0,09783279 ! neuromuscular process GO:0050905 99 50 0,000 0,08892781 0,09778808 ! regulation of ossification GO:0030278 117 50 0,000 0,08892781 0,09774341 ! inner ear development GO:0048839 79 50 0,000 0,08892781 0,09769878 ! histone modification GO:0016570 91 50 0,000 0,08892781 0,09765418 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,08892781 0,09760963 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,08892781 0,09756512 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,08892781 0,09752066 ! viral infectious cycle GO:0019058 99 51 0,000 0,09062469 0,09933622 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,09062469 0,09929099 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,09062469 0,09924579 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,09062469 0,09920064 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,09062469 0,09915553 ! chromatin remodeling GO:0006338 109 51 0,000 0,09062469 0,09911046 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,09062469 0,09906543 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,09062469 0,09902044 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,09062469 0,09897549 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,09062469 0,09893058 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,09062469 0,09888572 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,09231847 0,10068823 ! covalent chromatin modification GO:0016569 101 52 0,000 0,09231847 0,1006426 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,09231847 0,10059702 ! amino acid activation GO:0043038 92 52 0,000 0,09231847 0,10055148 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,09231847 0,10050599 ! synapse organization GO:0050808 85 52 0,000 0,09231847 0,10046053 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,09400914 0,10225407 ! RNA catabolic process GO:0006401 93 53 0,000 0,09400914 0,10220786 ! regulation of translational initiation GO:0006446 82 53 0,000 0,09400914 0,1021617 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,09400914 0,10211557 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,09400914 0,10206949 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,09400914 0,10202345 ! cell maturation GO:0048469 100 53 0,000 0,09400914 0,10197745 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,09400914 0,1019315 ! response to UV GO:0009411 104 53 0,000 0,09400914 0,10188558 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,09569672 0,10366786 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,09569672 0,10362121 ! cell recognition GO:0008037 85 54 0,000 0,09569672 0,10357459 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,09569672 0,10352802 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,09569672 0,10348149 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,09569672 0,103435 ! chloride transport GO:0006821 90 55 0,000 0,09738122 0,10520845 ! glucose catabolic process GO:0006007 82 55 0,000 0,09738122 0,10516123 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,09738122 0,10511405 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,09738122 0,10506691 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,09738122 0,10501982 ! aging GO:0007568 103 55 0,000 0,09738122 0,10497277 ! gastrulation GO:0007369 112 55 0,000 0,09738122 0,10492576 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,09738122 0,10487879 ! RNA elongation GO:0006354 79 55 0,000 0,09738122 0,10483186 ! nuclear export GO:0051168 97 55 0,000 0,09738122 0,10478498 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,09738122 0,10473814 ! regulation of actin filament length GO:0030832 105 56 0,000 0,09906263 0,10649897 ! sensory perception of smell GO:0007608 80 56 0,000 0,09906263 0,1064514 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,09906263 0,10640388 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,09906263 0,1063564 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,09906263 0,10630896 ! proton transport GO:0015992 94 56 0,000 0,09906263 0,10626157 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,10074097 0,10801371 ! muscle fiber development GO:0048747 112 57 0,000 0,10074097 0,1079656 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,10074097 0,10791753 ! hydrogen transport GO:0006818 97 58 0,000 0,10241624 0,10966331 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,10241624 0,10961453 ! regulation of endocytosis GO:0030100 91 58 0,000 0,10241624 0,10956579 ! adult behavior GO:0030534 99 58 0,000 0,10241624 0,1095171 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,10241624 0,10946844 ! positive regulation of secretion GO:0051047 95 59 0,000 0,10408844 0,11120639 ! regulation of cellular component size GO:0032535 109 59 0,000 0,10408844 0,11115703 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,10408844 0,11110771 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,10408844 0,11105844 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,10408844 0,11100921 ! DNA catabolic process GO:0006308 86 59 0,000 0,10408844 0,11096003 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,10408844 0,11091089 ! establishment of organelle localization GO:0051656 109 59 0,000 0,10408844 0,11086179 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,10575758 0,11258971 ! regulation of heart contraction GO:0008016 110 60 0,000 0,10575758 0,11253991 ! camera-type eye development GO:0043010 116 60 0,000 0,10575758 0,11249016 ! kidney development GO:0001822 122 60 0,000 0,10575758 0,11244045 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,10742367 0,11416137 ! mesoderm development GO:0007498 119 61 0,000 0,10742367 0,11411097 ! tRNA processing GO:0008033 89 61 0,000 0,10742367 0,11406061 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,10742367 0,1140103 ! ear development GO:0043583 103 62 0,000 0,1090867 0,11572425 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,1090867 0,11567325 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,1090867 0,11562229 ! regulation of mitosis GO:0007088 105 63 0,000 0,1107467 0,11733006 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,1107467 0,11727841 ! detection of external stimulus GO:0009581 91 63 0,000 0,1107467 0,11722682 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,1107467 0,11717527 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,1107467 0,11712376 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,11240366 0,1188239 ! cell redox homeostasis GO:0045454 102 64 0,000 0,11240366 0,11877172 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,11240366 0,11871958 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,11240366 0,11866748 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,11405758 0,12036076 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,11405758 0,120308 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,11405758 0,12025528 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,11405758 0,1202026 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,11405758 0,12014997 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,11570848 0,12183571 ! extracellular matrix organization GO:0030198 133 66 0,000 0,11570848 0,12178241 ! developmental maturation GO:0021700 116 66 0,000 0,11570848 0,12172916 ! cell projection assembly GO:0030031 120 66 0,000 0,11570848 0,12167596 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,11735635 0,12335491 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,11735635 0,12330104 ! lung development GO:0030324 144 67 0,000 0,11735635 0,12324722 ! chromosome segregation GO:0007059 113 67 0,000 0,11735635 0,12319345 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,11735635 0,12313972 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,11735635 0,12308605 ! hexose catabolic process GO:0019320 104 67 0,000 0,11735635 0,12303241 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,11735635 0,12297883 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,11735635 0,12292529 ! amino acid transport GO:0006865 125 68 0,000 0,11900121 0,12459396 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,11900121 0,12453977 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,11900121 0,12448562 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,11900121 0,12443152 ! regulation of lipase activity GO:0060191 130 68 0,000 0,11900121 0,12437746 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,11900121 0,12432346 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,12064306 0,12598403 ! negative regulation of cell size GO:0045792 134 69 0,000 0,12064306 0,12592938 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,12064306 0,12587477 ! urogenital system development GO:0001655 137 69 0,000 0,12064306 0,1258202 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,12064306 0,12576569 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,12064306 0,12571122 ! antigen processing and presentation GO:0019882 104 69 0,000 0,12064306 0,1256568 ! appendage morphogenesis GO:0035107 135 70 0,000 0,12228191 0,12730864 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,12228191 0,12725358 ! amine catabolic process GO:0009310 117 71 0,000 0,12391775 0,12890018 ! appendage development GO:0048736 136 71 0,000 0,12391775 0,12884447 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,12391775 0,12878882 ! regulation of immune effector process GO:0002697 137 71 0,000 0,12391775 0,12873321 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,1255506 0,13037322 ! carbohydrate transport GO:0008643 110 72 0,000 0,1255506 0,13031697 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,1255506 0,13026078 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,1255506 0,13020463 ! respiratory system development GO:0060541 153 72 0,000 0,1255506 0,13014853 ! regulation of blood pressure GO:0008217 125 73 0,000 0,12718046 0,13178131 ! axon guidance GO:0007411 139 73 0,000 0,12718046 0,13172458 ! fertilization GO:0009566 90 73 0,000 0,12718046 0,1316679 ! transition metal ion transport GO:0000041 126 74 0,000 0,12880734 0,13329482 ! exocytosis GO:0006887 133 74 0,000 0,12880734 0,13323751 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,12880734 0,13318026 ! eye development GO:0001654 143 74 0,000 0,12880734 0,13312305 ! organelle localization GO:0051640 136 74 0,000 0,12880734 0,13306589 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,13043124 0,13468565 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,13043124 0,13462787 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,13043124 0,13457014 ! rhythmic process GO:0048511 128 75 0,000 0,13043124 0,13451246 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,13043124 0,13445482 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,13205216 0,13606745 ! defense response to bacterium GO:0042742 89 76 0,000 0,13205216 0,13600921 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,13205216 0,13595101 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,13367012 0,13755788 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,13367012 0,13749907 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,13367012 0,1374403 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,13367012 0,13738159 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,13528512 0,13898206 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,13528512 0,13892275 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,13528512 0,13886348 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,13689716 0,14045823 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,13689716 0,14039836 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,13689716 0,14033854 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,13689716 0,14027877 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,13689716 0,14021905 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,13689716 0,14015939 ! muscle cell differentiation GO:0042692 159 80 0,000 0,13850624 0,1417465 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,13850624 0,14168623 ! protein import into nucleus GO:0006606 158 80 0,000 0,13850624 0,14162602 ! inorganic anion transport GO:0015698 138 80 0,000 0,13850624 0,14156585 ! T cell activation GO:0042110 168 81 0,000 0,14011238 0,14314667 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,14011238 0,14308591 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 0,000 0,14011238 0,1430252 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,14011238 0,14296454 ! nuclear import GO:0051170 161 81 0,000 0,14011238 0,14290394 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,14011238 0,14284339 ! negative regulation of growth GO:0045926 155 84 0,000 0,14491318 0,14767519 ! regulation of ligase activity GO:0051340 142 84 0,000 0,14491318 0,14761266 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,14491318 0,1475502 ! response to unfolded protein GO:0006986 131 85 0,000 0,14650759 0,14911052 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,14650759 0,14904747 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,14650759 0,14898447 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,14809908 0,15053924 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,14809908 0,15047567 ! tube morphogenesis GO:0035239 176 86 0,000 0,14809908 0,15041215 ! mitochondrion organization GO:0007005 148 86 0,000 0,14809908 0,15034868 ! alcohol catabolic process GO:0046164 130 86 0,000 0,14809908 0,15028527 ! amine transport GO:0015837 155 86 0,000 0,14809908 0,15022191 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,14968765 0,15176927 ! protein localization in nucleus GO:0034504 176 87 0,000 0,14968765 0,15170535 ! cellular respiration GO:0045333 135 88 0,000 0,15127332 0,15324783 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,15127332 0,15318333 ! regulation of neurological system process GO:0031644 148 88 0,000 0,15127332 0,15311889 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,15127332 0,1530545 ! cellular defense response GO:0006968 114 89 0,000 0,15285608 0,15459089 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,15285608 0,15452593 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,15285608 0,15446103 ! ossification GO:0001503 188 90 0,000 0,15443594 0,15599197 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,15443594 0,15592651 ! bone development GO:0060348 189 91 0,000 0,1560129 0,15745262 ! response to protein stimulus GO:0051789 149 91 0,000 0,1560129 0,1573866 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,1560129 0,15732064 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,15758698 0,15884134 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,15915818 0,16035786 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,15915818 0,16029074 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,16072649 0,16180249 ! female pregnancy GO:0007565 164 94 0,000 0,16072649 0,16173481 ! transcription initiation GO:0006352 153 94 0,000 0,16072649 0,1616672 ! regulation of T cell activation GO:0050863 158 94 0,000 0,16072649 0,16159964 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,16229194 0,16310543 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,16229194 0,16303733 ! leukocyte differentiation GO:0002521 202 96 0,000 0,16385451 0,16453838 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,16385451 0,16446974 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,16385451 0,16440115 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,16541423 0,16589689 ! protein ubiquitination GO:0016567 217 97 0,000 0,16541423 0,16582776 ! response to virus GO:0009615 160 98 0,000 0,16697108 0,16731879 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,16697108 0,16724913 ! interphase GO:0051325 213 98 0,000 0,16697108 0,16717953 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,16697108 0,16710999 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,16852508 0,16859516 ! cell cycle arrest GO:0007050 213 100 0,000 0,17007624 0,17007624