pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1324-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of vasoconstriction GO:0045907 10 5 2,000 6,384E-08 1,56E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 6,735E-08 8,226E-05 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,958E-07 1,595E-04 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 2,228E-07 1,361E-04 ! positive regulation of microtubule polymerization GO:0031116 15 7 2,000 2,228E-07 1,089E-04 ! regulation of MAPKKK cascade GO:0043408 157 72 4,000 2,594E-07 1,056E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 3,561E-07 1,243E-04 ! gas homeostasis GO:0033483 14 8 2,000 3,561E-07 1,087E-04 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 2,000 3,561E-07 9,665E-05 ! regulation of microtubule polymerization GO:0031113 17 8 2,000 3,561E-07 8,699E-05 ! regulation of epithelial cell differentiation GO:0030856 18 9 2,000 5,334E-07 1,185E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 5,334E-07 1,086E-04 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 7,609E-07 1,43E-04 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 8,108E-07 1,415E-04 ! gland development GO:0048732 220 91 4,000 8,386E-07 1,366E-04 ! mammary gland development GO:0030879 93 40 3,000 1,001E-06 1,528E-04 ! T cell receptor signaling pathway GO:0050852 29 11 2,000 1,045E-06 1,502E-04 ! gland morphogenesis GO:0022612 31 13 2,000 1,806E-06 2,451E-04 ! response to insulin stimulus GO:0032868 98 47 3,000 1,934E-06 2,487E-04 ! lipid localization GO:0010876 32 14 2,000 2,296E-06 2,804E-04 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 2,000 2,296E-06 2,671E-04 ! regulation of vasodilation GO:0042312 27 15 2,000 2,866E-06 3,182E-04 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 2,000 4,271E-06 4,537E-04 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 2,000 4,271E-06 4,348E-04 ! positive regulation of cell migration GO:0030335 137 58 3,000 4,53E-06 4,427E-04 ! positive regulation of protein complex assembly GO:0031334 34 18 2,000 5,119E-06 4,81E-04 ! DNA integration GO:0015074 32 18 2,000 5,119E-06 4,631E-04 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 6,727E-06 5,869E-04 ! regulation of fatty acid metabolic process GO:0019217 45 20 2,000 7,132E-06 6,008E-04 ! positive regulation of cell motion GO:0051272 157 65 3,000 7,158E-06 5,829E-04 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 7,609E-06 5,996E-04 ! regulation of vasoconstriction GO:0019229 40 21 2,000 8,309E-06 6,344E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 9,088E-06 6,728E-04 ! inactivation of MAPK activity GO:0000188 45 22 2,000 9,608E-06 6,904E-04 ! negative regulation of kinase activity GO:0033673 145 70 3,000 9,625E-06 6,718E-04 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,201E-05 8,151E-04 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 2,000 1,259E-05 8,315E-04 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 1,259E-05 8,097E-04 ! membrane depolarization GO:0051899 45 24 2,000 1,259E-05 7,889E-04 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 1,259E-05 7,692E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 1,259E-05 7,504E-04 ! vasculogenesis GO:0001570 49 25 2,000 1,429E-05 8,313E-04 ! regulation of smooth muscle contraction GO:0006940 48 26 2,000 1,613E-05 9,167E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 1,613E-05 8,958E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 2,000 1,613E-05 8,759E-04 ! regulation of blood coagulation GO:0030193 46 26 2,000 1,613E-05 8,569E-04 ! response to hypoxia GO:0001666 178 81 3,000 1,72E-05 8,938E-04 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 1,813E-05 9,226E-04 ! response to oxygen levels GO:0070482 183 83 3,000 1,894E-05 9,442E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 2,027E-05 9,906E-04 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 2,081E-05 9,968E-04 ! negative regulation of protein kinase cascade GO:0010741 72 30 2,000 2,506E-05 1,177E-03 ! immune response-activating signal transduction GO:0002757 58 30 2,000 2,506E-05 1,155E-03 GO:0002764|immune response-regulating signal transduction, ! regulation of coagulation GO:0050818 52 30 2,000 2,506E-05 1,134E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 2,771E-05 1,231E-03 ! cholesterol homeostasis GO:0042632 60 33 2,000 3,354E-05 1,463E-03 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 2,000 3,354E-05 1,437E-03 ! parathyroid gland development GO:0060017 14 5 1,000 3,487E-05 1,469E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,487E-05 1,444E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 3,487E-05 1,42E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 3,645E-05 1,46E-03 ! cholesterol transport GO:0030301 62 34 2,000 3,674E-05 1,447E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 3,674E-05 1,425E-03 ! skeletal muscle tissue development GO:0007519 223 100 3,000 3,945E-05 1,506E-03 GO:0060538|skeletal muscle organ development, ! sterol transport GO:0015918 63 35 2,000 4,013E-05 1,508E-03 ! tissue remodeling GO:0048771 78 37 2,000 4,751E-05 1,758E-03 ! regulation of microtubule-based process GO:0032886 86 37 2,000 4,751E-05 1,732E-03 ! neutral lipid metabolic process GO:0006638 54 38 2,000 5,151E-05 1,851E-03 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 75 40 2,000 6,016E-05 2,13E-03 ! glycerol ether metabolic process GO:0006662 57 40 2,000 6,016E-05 2,1E-03 ! organic ether metabolic process GO:0018904 59 42 2,000 6,972E-05 2,399E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 7,306E-05 2,479E-03 ! vesicle fusion GO:0006906 20 7 1,000 7,306E-05 2,445E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 8,583E-05 2,834E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 9,169E-05 2,987E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 9,729E-05 3,127E-03 ! male meiosis GO:0007140 9 8 1,000 9,729E-05 3,087E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 9,729E-05 3,047E-03 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 9,729E-05 3,009E-03 ! regulation of JNK cascade GO:0046328 104 47 2,000 9,781E-05 2,987E-03 ! regulation of JAK-STAT cascade GO:0046425 76 48 2,000 1,042E-04 3,143E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 2,000 1,042E-04 3,104E-03 ! positive regulation of DNA binding GO:0043388 83 48 2,000 1,042E-04 3,067E-03 ! JNK cascade GO:0007254 106 49 2,000 1,108E-04 3,224E-03 ! protein homooligomerization GO:0051260 84 49 2,000 1,108E-04 3,186E-03 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 1,000 1,249E-04 3,549E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 1,249E-04 3,508E-03 ! S phase GO:0051320 10 9 1,000 1,249E-04 3,468E-03 GO:0000084|S phase of mitotic cell cycle, ! stress-activated protein kinase signaling pathway GO:0031098 113 51 2,000 1,249E-04 3,43E-03 ! positive regulation of binding GO:0051099 88 52 2,000 1,324E-04 3,594E-03 ! vesicle organization GO:0016050 127 53 2,000 1,402E-04 3,763E-03 ! regulation of muscle contraction GO:0006937 94 54 2,000 1,482E-04 3,936E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,56E-04 4,097E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,56E-04 4,054E-03 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 1,56E-04 4,011E-03 ! regulation of protein polymerization GO:0032271 117 55 2,000 1,566E-04 3,984E-03 ! response to UV GO:0009411 120 55 2,000 1,566E-04 3,943E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 1,741E-04 4,341E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 1,834E-04 4,526E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,904E-04 4,652E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,904E-04 4,606E-03 ! thymus development GO:0048538 29 11 1,000 1,904E-04 4,561E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,282E-04 5,413E-03 ! hippocampus development GO:0021766 29 12 1,000 2,282E-04 5,361E-03 ! histone acetylation GO:0016573 27 12 1,000 2,282E-04 5,31E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,282E-04 5,26E-03 ! localization within membrane GO:0051668 26 12 1,000 2,282E-04 5,211E-03 ! regulation of protein complex assembly GO:0043254 132 63 2,000 2,344E-04 5,303E-03 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 2,456E-04 5,506E-03 ! organelle fusion GO:0048284 36 13 1,000 2,694E-04 5,983E-03 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,694E-04 5,929E-03 ! regulation of cellular response to stress GO:0080135 142 68 2,000 2,939E-04 6,41E-03 ! activation of immune response GO:0002253 120 70 2,000 3,201E-04 6,921E-03 ! actin filament organization GO:0007015 167 72 2,000 3,479E-04 7,455E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 3,617E-04 7,685E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,617E-04 7,619E-03 ! cell-matrix adhesion GO:0007160 181 76 2,000 4,078E-04 8,516E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 4,129E-04 8,549E-03 ! protein oligomerization GO:0051259 149 79 2,000 4,569E-04 9,38E-03 ! signal complex assembly GO:0007172 47 17 1,000 4,674E-04 9,516E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 4,674E-04 9,437E-03 ! regulation of peptidase activity GO:0052547 150 82 2,000 5,096E-04 0,01020534 ! cell-substrate adhesion GO:0031589 189 82 2,000 5,096E-04 0,01012237 ! limbic system development GO:0021761 40 18 1,000 5,252E-04 0,0103472 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 5,252E-04 0,01026442 ! cerebral cortex development GO:0021987 40 19 1,000 5,863E-04 0,01136711 ! regulation of DNA binding GO:0051101 167 89 2,000 6,474E-04 0,01245379 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 6,506E-04 0,01241765 ! protein amino acid acetylation GO:0006473 41 20 1,000 6,506E-04 0,01232139 ! actin filament bundle formation GO:0051017 47 20 1,000 6,506E-04 0,01222661 ! lipid phosphorylation GO:0046834 43 21 1,000 7,182E-04 0,01339415 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 7,358E-04 0,01361814 ! regulation of membrane potential GO:0042391 179 94 2,000 7,591E-04 0,01394259 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 7,828E-04 0,01427062 ! positive regulation of B cell activation GO:0050871 42 22 1,000 7,891E-04 0,01427963 ! activation of JUN kinase activity GO:0007257 47 22 1,000 7,891E-04 0,01417463 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 8,632E-04 0,01539254 ! positive regulation of immune response GO:0050778 175 100 2,000 9,083E-04 0,01607977 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 9,405E-04 0,01653013 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 9,405E-04 0,01641205 ! pallium development GO:0021543 56 24 1,000 9,405E-04 0,01629566 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,021E-03 0,01756655 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,021E-03 0,01744371 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,021E-03 0,01732257 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,105E-03 0,01861405 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 1,105E-03 0,01848655 ! cellular response to oxidative stress GO:0034599 43 27 1,000 1,192E-03 0,01980556 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 1,282E-03 0,0211592 ! protein amino acid acylation GO:0043543 59 28 1,000 1,282E-03 0,02101719 ! vesicle docking GO:0048278 55 28 1,000 1,282E-03 0,02087708 ! negative regulation of protein modification process GO:0031400 66 28 1,000 1,282E-03 0,02073882 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,282E-03 0,02060238 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 1,282E-03 0,02046772 ! respiratory gaseous exchange GO:0007585 61 29 1,000 1,375E-03 0,02181456 ! somitogenesis GO:0001756 52 29 1,000 1,375E-03 0,02167382 ! regulation of B cell activation GO:0050864 55 30 1,000 1,472E-03 0,02304506 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 1,571E-03 0,02444774 ! membrane docking GO:0022406 69 35 1,000 2,001E-03 0,03093389 ! telencephalon development GO:0021537 81 35 1,000 2,001E-03 0,03073934 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,001E-03 0,03054722 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 2,479E-03 0,03762335 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 82 40 1,000 2,607E-03 0,0393113 ! mismatch repair GO:0006298 58 40 1,000 2,607E-03 0,03907013 ! feeding behavior GO:0007631 69 41 1,000 2,737E-03 0,04077375 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 3,007E-03 0,04452054 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 3,007E-03 0,04425234 ! neuron migration GO:0001764 85 43 1,000 3,007E-03 0,04398736 ! response to reactive oxygen species GO:0000302 75 44 1,000 3,146E-03 0,04575215 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 3,289E-03 0,04753914 ! positive regulation of cell cycle GO:0045787 96 48 1,000 3,733E-03 0,05365161 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 3,888E-03 0,05554017 ! endocrine system development GO:0035270 109 50 1,000 4,045E-03 0,0574483 ! histone modification GO:0016570 104 52 1,000 4,368E-03 0,0616757 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 4,533E-03 0,06364882 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! activation of phospholipase C activity GO:0007202 110 54 1,000 4,702E-03 0,06563957 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 4,702E-03 0,06526662 ! covalent chromatin modification GO:0016569 115 54 1,000 4,702E-03 0,06489788 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 4,874E-03 0,06688742 ! regulation of phospholipase activity GO:0010517 113 57 1,000 5,225E-03 0,07131251 ! positive regulation of lipase activity GO:0060193 115 58 1,000 5,405E-03 0,07336016 ! lipid modification GO:0030258 112 60 1,000 5,774E-03 0,07792969 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 5,962E-03 0,08003174 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 6,154E-03 0,08214806 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 6,544E-03 0,08689173 ! negative regulation of cell growth GO:0030308 142 67 1,000 7,151E-03 0,09443797 ! activation of MAPK activity GO:0000187 124 67 1,000 7,151E-03 0,09393024 ! regulation of lipase activity GO:0060191 137 68 1,000 7,359E-03 0,09614274 ! negative regulation of cell size GO:0045792 144 69 1,000 7,57E-03 0,09836699 ! lung development GO:0030324 165 69 1,000 7,57E-03 0,09784653 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 7,57E-03 0,09733155 ! respiratory tube development GO:0030323 171 72 1,000 8,218E-03 0,10510701 ! respiratory system development GO:0060541 175 74 1,000 8,663E-03 0,11022443 ! regulation of transcription factor activity GO:0051090 137 75 1,000 8,889E-03 0,11252148 GO:0090046|regulation of transcription regulator activity, ! axon guidance GO:0007411 162 75 1,000 8,889E-03 0,11194148 ! learning or memory GO:0007611 161 76 1,000 9,119E-03 0,11423925 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 9,35E-03 0,11654638 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 9,39E-03 0,11644553 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 9,39E-03 0,11585742 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 9,39E-03 0,11527522 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,39E-03 0,11469885 ! positive regulation of helicase activity GO:0051096 12 5 0,000 9,39E-03 0,1141282 ! neuron fate determination GO:0048664 7 5 0,000 9,39E-03 0,11356321 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,39E-03 0,11300379 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 9,39E-03 0,11244985 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 9,39E-03 0,11190131 ! polyol transport GO:0015791 12 5 0,000 9,39E-03 0,1113581 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,39E-03 0,11082014 ! response to superoxide GO:0000303 10 5 0,000 9,39E-03 0,11028735 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,39E-03 0,10975966 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 9,39E-03 0,109237 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 9,39E-03 0,10871928 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,39E-03 0,10820646 ! female meiosis GO:0007143 10 5 0,000 9,39E-03 0,10769845 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 9,39E-03 0,10719518 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,39E-03 0,1066966 ! hypothalamus development GO:0021854 9 5 0,000 9,39E-03 0,10620263 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 9,39E-03 0,10571322 ! cobalt ion transport GO:0006824 11 5 0,000 9,39E-03 0,1052283 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 9,39E-03 0,1047478 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 9,39E-03 0,10427168 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,39E-03 0,10379986 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,39E-03 0,10333229 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 9,39E-03 0,10286892 ! embryonic camera-type eye development GO:0031076 12 5 0,000 9,39E-03 0,10240968 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,39E-03 0,10195453 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,39E-03 0,1015034 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 9,39E-03 0,10105625 ! transposition GO:0032196 9 5 0,000 9,39E-03 0,10061302 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 9,39E-03 0,10017366 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 9,39E-03 0,09973813 ! negative chemotaxis GO:0050919 16 5 0,000 9,39E-03 0,09930636 ! positive regulation of histone modification GO:0031058 6 5 0,000 9,39E-03 0,09887831 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,39E-03 0,09845394 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 9,39E-03 0,0980332 ! behavioral response to pain GO:0048266 10 5 0,000 9,39E-03 0,09761604 ! clathrin coat assembly GO:0048268 15 5 0,000 9,39E-03 0,09720241 ! Notch receptor processing GO:0007220 11 5 0,000 9,39E-03 0,09679227 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,39E-03 0,09638558 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 9,39E-03 0,0959823 ! micturition GO:0060073 9 5 0,000 9,39E-03 0,09558237 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,39E-03 0,09518576 ! copulation GO:0007620 9 5 0,000 9,39E-03 0,09479243 ! glial cell fate commitment GO:0021781 14 5 0,000 9,39E-03 0,09440234 ! protein maturation by protein folding GO:0022417 14 5 0,000 9,39E-03 0,09401545 ! bioluminescence GO:0008218 9 5 0,000 9,39E-03 0,09363171 ! spermidine metabolic process GO:0008216 7 5 0,000 9,39E-03 0,09325109 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,39E-03 0,09287356 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,39E-03 0,09249907 ! apoptotic cell clearance GO:0043277 23 5 0,000 9,39E-03 0,09212759 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,39E-03 0,09175908 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 9,39E-03 0,0913935 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,39E-03 0,09103083 ! grooming behavior GO:0007625 6 5 0,000 9,39E-03 0,09067102 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 9,39E-03 0,09031405 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,39E-03 0,08995988 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 9,39E-03 0,08960847 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,39E-03 0,0892598 ! response to protozoan GO:0001562 13 5 0,000 9,39E-03 0,08891383 ! positive regulation of glycolysis GO:0045821 13 5 0,000 9,39E-03 0,08857054 ! lymph vessel development GO:0001945 10 5 0,000 9,39E-03 0,08822988 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 9,39E-03 0,08789184 ! endochondral ossification GO:0001958 17 5 0,000 9,39E-03 0,08755637 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,39E-03 0,08722346 ! single strand break repair GO:0000012 8 5 0,000 9,39E-03 0,08689306 ! anagen GO:0042640 7 5 0,000 9,39E-03 0,08656517 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,39E-03 0,08623973 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,39E-03 0,08591674 ! cytokine secretion GO:0050663 15 5 0,000 9,39E-03 0,08559615 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 9,39E-03 0,08527795 ! ceramide catabolic process GO:0046514 7 5 0,000 9,39E-03 0,08496211 ! skeletal myofibril assembly GO:0014866 12 5 0,000 9,39E-03 0,08464859 ! smooth muscle tissue development GO:0048745 32 5 0,000 9,39E-03 0,08433739 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,39E-03 0,08402846 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,39E-03 0,08372178 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,39E-03 0,08341734 ! cardiac muscle fiber development GO:0048739 12 5 0,000 9,39E-03 0,08311511 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,39E-03 0,08281505 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 9,39E-03 0,08251715 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,39E-03 0,08222139 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 9,39E-03 0,08192775 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,39E-03 0,08163619 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 9,39E-03 0,0813467 ! glycine biosynthetic process GO:0006545 7 5 0,000 9,39E-03 0,08105925 ! microvillus organization GO:0032528 8 5 0,000 9,39E-03 0,08077383 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 9,39E-03 0,08049042 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 9,39E-03 0,08020898 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 9,39E-03 0,07992951 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 9,39E-03 0,07965198 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 9,39E-03 0,07937636 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 9,39E-03 0,07910265 ! polyol catabolic process GO:0046174 9 5 0,000 9,39E-03 0,07883082 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 9,39E-03 0,07856085 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 9,39E-03 0,07829273 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 9,39E-03 0,07802643 ! muscle cell migration GO:0014812 8 5 0,000 9,39E-03 0,07776193 ! mitochondrial fission GO:0000266 8 5 0,000 9,39E-03 0,07749922 ! sister chromatid cohesion GO:0007062 15 5 0,000 9,39E-03 0,07723828 ! response to tumor necrosis factor GO:0034612 10 5 0,000 9,39E-03 0,07697909 ! mRNA transcription GO:0009299 10 5 0,000 9,39E-03 0,07672164 ! nerve growth factor processing GO:0032455 9 5 0,000 9,39E-03 0,0764659 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 9,39E-03 0,07621186 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 9,39E-03 0,0759595 ! anaerobic glycolysis GO:0019642 6 5 0,000 9,39E-03 0,07570881 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,39E-03 0,07545977 ! monocyte activation GO:0042117 10 5 0,000 9,39E-03 0,07521236 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,39E-03 0,07496657 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,39E-03 0,07472237 ! response to food GO:0032094 6 5 0,000 9,39E-03 0,07447977 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,39E-03 0,07423873 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,39E-03 0,07399926 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 9,39E-03 0,07376132 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,39E-03 0,0735249 ! forebrain neuron development GO:0021884 13 5 0,000 9,39E-03 0,07329 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,39E-03 0,07305659 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 9,39E-03 0,07282466 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 9,39E-03 0,07259421 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,39E-03 0,0723652 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,39E-03 0,07213764 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 9,39E-03 0,0719115 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,39E-03 0,07168678 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 9,39E-03 0,07146346 ! lipid glycosylation GO:0030259 7 5 0,000 9,39E-03 0,07124152 ! nucleobase transport GO:0015851 6 5 0,000 9,39E-03 0,07102096 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,39E-03 0,07080176 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 9,39E-03 0,0705839 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 9,39E-03 0,07036739 ! basic amino acid transport GO:0015802 12 5 0,000 9,39E-03 0,0701522 ! cellular glucose homeostasis GO:0001678 6 5 0,000 9,39E-03 0,06993832 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 9,39E-03 0,06972574 ! actin nucleation GO:0045010 11 5 0,000 9,39E-03 0,06951445 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,39E-03 0,06930444 ! depurination GO:0045007 5 5 0,000 9,39E-03 0,06909569 ! depyrimidination GO:0045008 10 5 0,000 9,39E-03 0,0688882 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,39E-03 0,06868194 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,39E-03 0,06847692 ! G2/M transition checkpoint GO:0031576 8 5 0,000 9,39E-03 0,06827312 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,39E-03 0,06807053 ! zinc ion homeostasis GO:0055069 9 5 0,000 9,39E-03 0,06786914 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 9,39E-03 0,06766894 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 9,39E-03 0,06746991 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,39E-03 0,06727205 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,39E-03 0,06707535 ! activated T cell proliferation GO:0050798 16 5 0,000 9,39E-03 0,06687979 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,39E-03 0,06668538 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 9,39E-03 0,06649208 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,39E-03 0,06629991 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,39E-03 0,06610884 ! gamma-delta T cell activation GO:0046629 6 5 0,000 9,39E-03 0,06591888 ! response to arsenic GO:0046685 11 5 0,000 9,39E-03 0,06573 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 9,39E-03 0,0655422 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 9,39E-03 0,06535547 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 9,39E-03 0,0651698 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 9,39E-03 0,06498518 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 9,39E-03 0,06480161 ! response to mercury ion GO:0046689 8 5 0,000 9,39E-03 0,06461907 ! response to cadmium ion GO:0046686 7 5 0,000 9,39E-03 0,06443755 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 9,39E-03 0,06425706 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 9,39E-03 0,06407757 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 9,39E-03 0,06389908 ! bile acid biosynthetic process GO:0006699 7 5 0,000 9,39E-03 0,06372158 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 9,39E-03 0,06354507 ! ganglioside catabolic process GO:0006689 12 5 0,000 9,39E-03 0,06336953 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,39E-03 0,06319496 ! decidualization GO:0046697 11 5 0,000 9,39E-03 0,06302134 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 9,39E-03 0,06284868 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 9,39E-03 0,06267696 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 9,39E-03 0,06250618 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 9,39E-03 0,06233633 ! embryonic cleavage GO:0040016 6 5 0,000 9,39E-03 0,0621674 ! peroxisome fission GO:0016559 5 5 0,000 9,39E-03 0,06199938 ! histone demethylation GO:0016577 13 5 0,000 9,39E-03 0,06183226 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 9,39E-03 0,06166605 ! mitotic recombination GO:0006312 9 5 0,000 9,39E-03 0,06150072 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 9,39E-03 0,06133628 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,39E-03 0,06117272 ! metaphase plate congression GO:0051310 7 5 0,000 9,39E-03 0,06101002 ! regulation of sterol transport GO:0032371 7 5 0,000 9,39E-03 0,06084819 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,39E-03 0,06068722 ! enteric nervous system development GO:0048484 8 5 0,000 9,39E-03 0,0605271 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 9,39E-03 0,06036781 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 9,39E-03 0,06020937 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 9,39E-03 0,06005175 ! muscle cell proliferation GO:0033002 12 5 0,000 9,39E-03 0,05989496 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,39E-03 0,05973898 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 9,39E-03 0,05958382 ! B cell homeostasis GO:0001782 13 5 0,000 9,39E-03 0,05942945 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 9,39E-03 0,05927589 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,39E-03 0,05912312 ! metaphase GO:0051323 11 5 0,000 9,39E-03 0,05897113 ! melatonin biosynthetic process GO:0030187 7 5 0,000 9,39E-03 0,05881992 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 9,39E-03 0,05866949 ! cellular response to nutrient GO:0031670 8 5 0,000 9,39E-03 0,05851982 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,39E-03 0,05837091 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 9,39E-03 0,05822276 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 9,39E-03 0,05807536 ! regulation of hair follicle development GO:0051797 10 5 0,000 9,39E-03 0,05792871 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 9,39E-03 0,05778279 ! response to redox state GO:0051775 6 5 0,000 9,39E-03 0,05763761 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 9,39E-03 0,05749316 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 9,39E-03 0,05734942 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,39E-03 0,05720641 ! brown fat cell differentiation GO:0050873 7 5 0,000 9,39E-03 0,0570641 ! regulation of telomerase activity GO:0051972 7 5 0,000 9,39E-03 0,0569225 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,39E-03 0,05678161 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 9,39E-03 0,05664141 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,39E-03 0,05650189 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 9,39E-03 0,05636307 ! striatum development GO:0021756 14 5 0,000 9,39E-03 0,05622492 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 9,39E-03 0,05608745 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,39E-03 0,05595066 ! glial cell migration GO:0008347 10 5 0,000 9,39E-03 0,05581452 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,39E-03 0,05567905 ! neural plate morphogenesis GO:0001839 7 5 0,000 9,39E-03 0,05554424 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 9,39E-03 0,05541007 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,39E-03 0,05527655 ! T cell activation during immune response GO:0002286 9 5 0,000 9,39E-03 0,05514368 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,39E-03 0,05501144 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,39E-03 0,05487983 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 9,39E-03 0,05474885 ! neuroprotection GO:0043526 8 5 0,000 9,39E-03 0,0546185 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 9,39E-03 0,05448876 ! regulation of sensory perception GO:0051931 8 5 0,000 9,39E-03 0,05435964 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,39E-03 0,05423113 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,39E-03 0,05410323 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 9,39E-03 0,05397593 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 9,39E-03 0,05384922 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,39E-03 0,05372311 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 9,39E-03 0,05359759 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,39E-03 0,05347266 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 9,39E-03 0,0533483 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 9,39E-03 0,05322452 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,39E-03 0,05310132 ! spindle assembly GO:0051225 6 5 0,000 9,39E-03 0,05297868 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,39E-03 0,05285661 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,39E-03 0,0527351 ! protein palmitoylation GO:0018345 12 5 0,000 9,39E-03 0,05261415 ! drug metabolic process GO:0017144 7 5 0,000 9,39E-03 0,05249375 ! stem cell division GO:0017145 11 5 0,000 9,39E-03 0,0523739 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,39E-03 0,0522546 ! organ regeneration GO:0031100 7 5 0,000 9,39E-03 0,05213584 ! carnitine metabolic process GO:0009437 8 5 0,000 9,39E-03 0,05201762 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,39E-03 0,05189993 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 9,585E-03 0,05285762 ! meiosis GO:0007126 143 81 1,000 0,01030397 0,05669502 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01030397 0,05656762 ! meiotic cell cycle GO:0051321 144 82 1,000 0,01054882 0,05778201 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01079625 0,05900501 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01125755 0,06138883 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01125755 0,0612521 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01125755 0,06111599 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01125755 0,06098048 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01125755 0,06084556 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01125755 0,06071125 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01125755 0,06057752 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01125755 0,06044438 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01125755 0,06031183 ! response to oxygen radical GO:0000305 11 6 0,000 0,01125755 0,06017986 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01125755 0,06004846 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01125755 0,05991763 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01125755 0,05978738 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01125755 0,05965769 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01125755 0,05952856 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01125755 0,05939999 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01125755 0,05927197 ! forebrain regionalization GO:0021871 9 6 0,000 0,01125755 0,0591445 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01125755 0,05901758 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01125755 0,05889121 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01125755 0,05876537 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01125755 0,05864007 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01125755 0,05851531 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01125755 0,05839107 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01125755 0,05826736 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01125755 0,05814417 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01125755 0,05802151 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01125755 0,05789936 ! malate metabolic process GO:0006108 13 6 0,000 0,01125755 0,05777772 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01125755 0,05765659 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01125755 0,05753597 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01125755 0,05741585 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01125755 0,05729624 ! protein refolding GO:0042026 15 6 0,000 0,01125755 0,05717712 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01125755 0,05705849 ! opsonization GO:0008228 8 6 0,000 0,01125755 0,05694036 ! mating behavior GO:0007617 7 6 0,000 0,01125755 0,05682272 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01125755 0,05670556 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01125755 0,05658888 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01125755 0,05647268 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01125755 0,05635696 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01125755 0,05624171 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01125755 0,05612693 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01125755 0,05601262 ! toxin metabolic process GO:0009404 11 6 0,000 0,01125755 0,05589877 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01125755 0,05578538 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01125755 0,05567246 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01125755 0,05555999 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01125755 0,05544797 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01125755 0,05533641 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01125755 0,05522529 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01125755 0,05511462 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01125755 0,05500439 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01125755 0,0548946 ! thymic T cell selection GO:0045061 16 6 0,000 0,01125755 0,05478525 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01125755 0,05467633 ! protein lipoylation GO:0009249 10 6 0,000 0,01125755 0,05456785 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01125755 0,05445979 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01125755 0,05435216 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01125755 0,05424496 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01125755 0,05413818 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01125755 0,05403182 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01125755 0,05392587 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01125755 0,05382034 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01125755 0,05371522 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01125755 0,05361052 ! hyperosmotic response GO:0006972 10 6 0,000 0,01125755 0,05350621 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01125755 0,05340232 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01125755 0,05329883 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01125755 0,05319573 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01125755 0,05309304 ! urea metabolic process GO:0019627 7 6 0,000 0,01125755 0,05299074 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01125755 0,05288884 ! neutrophil activation GO:0042119 7 6 0,000 0,01125755 0,05278732 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01125755 0,0526862 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01125755 0,05258546 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01125755 0,0524851 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01125755 0,05238513 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01125755 0,05228554 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01125755 0,05218633 ! neuron apoptosis GO:0051402 15 6 0,000 0,01125755 0,05208749 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01125755 0,05198903 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01125755 0,05189093 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01125755 0,05179321 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01125755 0,05169585 ! carnitine transport GO:0015879 10 6 0,000 0,01125755 0,05159886 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01125755 0,05150224 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01125755 0,05140597 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01125755 0,05131006 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01125755 0,05121451 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01125755 0,05111932 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01125755 0,05102448 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01125755 0,05092999 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01125755 0,05083585 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01125755 0,05074206 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01125755 0,05064861 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01125755 0,0505555 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01125755 0,05046274 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01125755 0,05037032 ! response to UV-C GO:0010225 14 6 0,000 0,01125755 0,05027823 ! astrocyte development GO:0014002 16 6 0,000 0,01125755 0,05018649 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01125755 0,05009507 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01125755 0,05000399 ! interaction with symbiont GO:0051702 14 6 0,000 0,01125755 0,04991324 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01125755 0,04982282 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01125755 0,04973272 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01125755 0,04964295 ! response to copper ion GO:0046688 10 6 0,000 0,01125755 0,0495535 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01125755 0,04946438 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01125755 0,04937557 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01125755 0,04928709 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01125755 0,04919892 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01125755 0,04911106 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01125755 0,04902352 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01125755 0,04893629 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01125755 0,04884937 ! hair follicle maturation GO:0048820 8 6 0,000 0,01125755 0,04876276 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01125755 0,04867645 ! Schwann cell development GO:0014044 15 6 0,000 0,01125755 0,04859045 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01125755 0,04850475 ! response to pheromone GO:0019236 6 6 0,000 0,01125755 0,04841936 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01125755 0,04833426 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01125755 0,04824946 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01125755 0,04816496 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01125755 0,04808076 ! subpallium development GO:0021544 15 6 0,000 0,01125755 0,04799685 ! neural tube patterning GO:0021532 8 6 0,000 0,01125755 0,04791323 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01125755 0,0478299 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01125755 0,04774687 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01125755 0,04766412 ! G2 phase GO:0051319 16 6 0,000 0,01125755 0,04758165 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01125755 0,04749947 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01125755 0,04741758 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01125755 0,04733596 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01125755 0,04725463 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01125755 0,04717358 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01125755 0,0470928 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01125755 0,0470123 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01125755 0,04693207 ! receptor internalization GO:0031623 11 6 0,000 0,01125755 0,04685212 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01125755 0,04677244 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01125755 0,04669303 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01125755 0,04661389 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01125755 0,04653502 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01125755 0,04645641 ! protein deubiquitination GO:0016579 16 6 0,000 0,01125755 0,04637807 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01125755 0,04629999 ! protein destabilization GO:0031648 9 6 0,000 0,01125755 0,04622218 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01125755 0,04614462 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01125755 0,04606733 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01125755 0,04599029 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01125755 0,04591351 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01125755 0,04583699 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01125755 0,04576072 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01125755 0,04568471 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01125755 0,04560895 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01125755 0,04553343 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01125755 0,04545817 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01125755 0,04538316 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01125755 0,04530839 ! neural plate development GO:0001840 9 6 0,000 0,01125755 0,04523387 ! catecholamine transport GO:0051937 9 6 0,000 0,01125755 0,0451596 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01125755 0,04508556 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01125755 0,04501177 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01125755 0,04493823 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01125755 0,04486492 ! maternal placenta development GO:0001893 12 6 0,000 0,01125755 0,04479185 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01125755 0,04471902 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01125755 0,04464642 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01125755 0,04457406 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01125755 0,04450193 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01125755 0,04443004 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01125755 0,04435838 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01125755 0,04428695 GO:0055081|anion homeostasis, ! negative regulation of growth GO:0045926 168 85 1,000 0,01129877 0,04437764 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01155384 0,04530663 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 205 91 1,000 0,01286691 0,05037478 ! tRNA transcription GO:0009304 17 7 0,000 0,01312163 0,05128983 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01312163 0,0512079 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01312163 0,05112623 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01312163 0,05104482 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01312163 0,05096367 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01312163 0,05088277 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01312163 0,05080213 ! sleep GO:0030431 16 7 0,000 0,01312163 0,05072175 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01312163 0,05064162 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01312163 0,05056175 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01312163 0,05048212 ! prostate gland development GO:0030850 14 7 0,000 0,01312163 0,05040275 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01312163 0,05032362 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01312163 0,05024474 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01312163 0,05016611 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01312163 0,05008773 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01312163 0,05000959 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01312163 0,04993169 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01312163 0,04985404 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01312163 0,04977663 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01312163 0,04969945 ! glycolipid transport GO:0046836 11 7 0,000 0,01312163 0,04962252 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01312163 0,04954582 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01312163 0,04946936 ! neuron adhesion GO:0007158 14 7 0,000 0,01312163 0,04939314 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01312163 0,04931715 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01312163 0,04924139 ! mRNA stabilization GO:0048255 18 7 0,000 0,01312163 0,04916587 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01312163 0,04909058 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01312163 0,04901551 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01312163 0,04894068 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01312163 0,04886608 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01312163 0,0487917 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01312163 0,04871755 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01312163 0,04864362 ! lipoprotein transport GO:0042953 14 7 0,000 0,01312163 0,04856992 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01312163 0,04849644 ! rhythmic behavior GO:0007622 17 7 0,000 0,01312163 0,04842318 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01312163 0,04835015 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01312163 0,04827733 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01312163 0,04820473 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01312163 0,04813235 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01312163 0,04806019 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01312163 0,04798824 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01312163 0,04791651 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01312163 0,04784499 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01312163 0,04777369 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01312163 0,0477026 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01312163 0,04763172 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01312163 0,04756105 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01312163 0,04749059 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01312163 0,04742034 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01312163 0,04735029 ! spinal cord patterning GO:0021511 14 7 0,000 0,01312163 0,04728045 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01312163 0,04721082 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01312163 0,04714139 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01312163 0,04707217 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01312163 0,04700315 ! adrenal gland development GO:0030325 17 7 0,000 0,01312163 0,04693433 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01312163 0,04686571 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01312163 0,04679729 ! ovulation GO:0030728 10 7 0,000 0,01312163 0,04672908 ! adenohypophysis development GO:0021984 11 7 0,000 0,01312163 0,04666106 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01312163 0,04659324 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01312163 0,04652561 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01312163 0,04645818 ! microtubule nucleation GO:0007020 21 7 0,000 0,01312163 0,04639095 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01312163 0,04632391 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01312163 0,04625707 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01312163 0,04619041 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01312163 0,04612395 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01312163 0,04605768 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01312163 0,0459916 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01312163 0,04592571 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01312163 0,04586001 ! galactose metabolic process GO:0006012 13 7 0,000 0,01312163 0,0457945 ! response to dietary excess GO:0002021 8 7 0,000 0,01312163 0,04572917 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01312163 0,04566403 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01312163 0,04559907 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01312163 0,0455343 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01312163 0,04546971 ! organ growth GO:0035265 15 7 0,000 0,01312163 0,04540531 ! nucleoside transport GO:0015858 11 7 0,000 0,01312163 0,04534108 ! nucleoside salvage GO:0043174 11 7 0,000 0,01312163 0,04527704 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01312163 0,04521318 ! male sex determination GO:0030238 15 7 0,000 0,01312163 0,0451495 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01312163 0,045086 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01312163 0,04502268 ! parturition GO:0007567 16 7 0,000 0,01312163 0,04495953 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01312163 0,04489656 ! rRNA modification GO:0000154 14 7 0,000 0,01312163 0,04483377 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01312163 0,04477115 ! spindle checkpoint GO:0031577 16 7 0,000 0,01312163 0,04470871 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01312163 0,04464644 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01312163 0,04458435 ! monocyte differentiation GO:0030224 16 7 0,000 0,01312163 0,04452243 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01312163 0,04446067 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01312163 0,0443991 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01312163 0,04433769 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01312163 0,04427645 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01312163 0,04421537 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01312163 0,04415447 ! fibrinolysis GO:0042730 11 7 0,000 0,01312163 0,04409374 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01312163 0,04403317 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01312163 0,04397277 ! eating behavior GO:0042755 8 7 0,000 0,01312163 0,04391253 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01312163 0,04385246 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01312163 0,04379255 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01312163 0,04373281 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01312163 0,04367322 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01312163 0,0436138 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01312163 0,04355455 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01312163 0,04349545 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01312163 0,04343651 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01312163 0,04337774 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01312163 0,04331912 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01312163 0,04326066 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01312163 0,04320235 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01312163 0,04314421 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01312163 0,04308622 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01312163 0,04302838 ! histone ubiquitination GO:0016574 9 7 0,000 0,01312163 0,04297071 ! regulation of meiosis GO:0040020 12 7 0,000 0,01312163 0,04291318 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01312163 0,04285581 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01312163 0,04279859 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01312163 0,04274153 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01312163 0,04268462 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01312163 0,04262785 ! transcription termination GO:0006353 14 7 0,000 0,01312163 0,04257124 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01312163 0,04251478 ! anaphase GO:0051322 18 7 0,000 0,01312163 0,04245847 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01312163 0,04240231 ! axonal fasciculation GO:0007413 19 7 0,000 0,01312163 0,0423463 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01312163 0,04229043 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01312163 0,04223471 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01312163 0,04217914 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01312163 0,04212371 ! diuresis GO:0030146 12 7 0,000 0,01312163 0,04206843 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01312163 0,0420133 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01312163 0,04195831 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01312163 0,04190346 ! antibiotic transport GO:0042891 9 7 0,000 0,01312163 0,04184876 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01312163 0,04179419 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01312163 0,04173977 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01312163 0,0416855 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01312163 0,04163136 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01312163 0,04157736 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01312163 0,04152351 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01312163 0,04146979 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01312163 0,04141621 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01312163 0,04136277 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01312163 0,04130947 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01312163 0,0412563 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01312163 0,04120327 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01312163 0,04115038 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01312163 0,04109762 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01312163 0,041045 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01312163 0,04099251 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01312163 0,04094016 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01312163 0,04088794 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01312163 0,04083586 ! muscle adaptation GO:0043500 13 7 0,000 0,01312163 0,0407839 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01312163 0,04073208 ! retina homeostasis GO:0001895 12 7 0,000 0,01312163 0,04068039 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01312163 0,04062883 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01312163 0,0405774 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01312163 0,0405261 ! bone development GO:0060348 206 92 1,000 0,013137 0,04052232 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,01396202 0,04301288 ! forebrain development GO:0030900 210 98 1,000 0,01480898 0,04556465 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01498225 0,0460398 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01498225 0,04598196 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01498225 0,04592427 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01498225 0,04586672 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01498225 0,04580931 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01498225 0,04575205 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01498225 0,04569493 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01498225 0,04563796 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01498225 0,04558112 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01498225 0,04552443 ! meiotic prophase I GO:0007128 14 8 0,000 0,01498225 0,04546788 ! response to zinc ion GO:0010043 12 8 0,000 0,01498225 0,04541147 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01498225 0,04535519 ! oligopeptide transport GO:0006857 16 8 0,000 0,01498225 0,04529906 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01498225 0,04524307 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01498225 0,04518721 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01498225 0,04513149 ! signal peptide processing GO:0006465 12 8 0,000 0,01498225 0,04507591 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01498225 0,04502047 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01498225 0,04496516 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01498225 0,04490999 ! succinate metabolic process GO:0006105 17 8 0,000 0,01498225 0,04485495 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01498225 0,04480005 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01498225 0,04474528 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01498225 0,04469065 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01498225 0,04463615 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01498225 0,04458178 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01498225 0,04452754 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01498225 0,04447344 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01498225 0,04441947 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01498225 0,04436563 ! reflex GO:0060004 17 8 0,000 0,01498225 0,04431191 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01498225 0,04425833 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01498225 0,04420488 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01498225 0,04415156 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01498225 0,04409836 ! pigment granule organization GO:0048753 17 8 0,000 0,01498225 0,0440453 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01498225 0,04399236 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01498225 0,04393955 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01498225 0,04388686 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01498225 0,0438343 ! histidine catabolic process GO:0006548 10 8 0,000 0,01498225 0,04378187 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01498225 0,04372956 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01498225 0,04367738 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01498225 0,04362532 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01498225 0,04357338 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01498225 0,04352157 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01498225 0,04346988 ! melanin metabolic process GO:0006582 17 8 0,000 0,01498225 0,04341832 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01498225 0,04336687 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01498225 0,04331555 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01498225 0,04326435 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01498225 0,04321327 ! macrophage activation GO:0042116 13 8 0,000 0,01498225 0,04316231 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01498225 0,04311147 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01498225 0,04306075 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01498225 0,04301015 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01498225 0,04295967 ! purine salvage GO:0043101 12 8 0,000 0,01498225 0,04290931 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01498225 0,04285906 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01498225 0,04280894 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01498225 0,04275893 ! osteoblast development GO:0002076 17 8 0,000 0,01498225 0,04270903 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01498225 0,04265926 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01498225 0,04260959 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01498225 0,04256005 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01498225 0,04251062 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01498225 0,0424613 ! response to UV-B GO:0010224 17 8 0,000 0,01498225 0,0424121 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01498225 0,04236301 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01498225 0,04231404 ! intermediate filament organization GO:0045109 12 8 0,000 0,01498225 0,04226517 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01498225 0,04221643 ! cellular extravasation GO:0045123 13 8 0,000 0,01498225 0,04216779 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01498225 0,04211926 ! response to antibiotic GO:0046677 11 8 0,000 0,01498225 0,04207085 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01498225 0,04202255 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01498225 0,04197436 ! DNA topological change GO:0006265 12 8 0,000 0,01498225 0,04192628 ! response to tropane GO:0014073 15 8 0,000 0,01498225 0,04187831 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01498225 0,04183045 ! melanosome transport GO:0032402 13 8 0,000 0,01498225 0,0417827 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01498225 0,04173505 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01498225 0,04168752 ! mast cell activation GO:0045576 14 8 0,000 0,01498225 0,04164009 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01498225 0,04159277 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01498225 0,04154556 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01498225 0,04149846 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01498225 0,04145146 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01498225 0,04140457 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01498225 0,04135779 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01498225 0,04131111 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01498225 0,04126453 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01498225 0,04121806 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01498225 0,0411717 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01498225 0,04112544 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01498225 0,04107928 ! response to tumor cell GO:0002347 16 8 0,000 0,01498225 0,04103323 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01498225 0,04098728 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01498225 0,04094143 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01498225 0,04089569 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01498225 0,04085005 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01498225 0,04080451 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01498225 0,04075907 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01498225 0,04071373 ! hormone catabolic process GO:0042447 17 8 0,000 0,01498225 0,04066849 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01498225 0,04062335 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01498225 0,04057832 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01498225 0,04053338 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01498225 0,04048854 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01498225 0,0404438 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01498225 0,04039916 ! adult feeding behavior GO:0008343 10 8 0,000 0,01498225 0,04035462 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01498225 0,04031018 ! ATP catabolic process GO:0006200 11 8 0,000 0,01498225 0,04026583 ! blastocyst growth GO:0001832 19 8 0,000 0,01498225 0,04022158 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01498225 0,04017743 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01498225 0,04013338 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01498225 0,04008942 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01498225 0,04004556 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01498225 0,04000179 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01498225 0,03995812 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01498225 0,03991455 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01498225 0,03987107 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01498225 0,03982768 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01498225 0,03978439 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01498225 0,0397412 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01498225 0,03969809 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01498225 0,03965508 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01498225 0,03961217 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01498225 0,03956934 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01498225 0,03952661 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01498225 0,03948397 ! axon extension GO:0048675 16 9 0,000 0,01683942 0,04433049 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01683942 0,04428277 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01683942 0,04423515 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01683942 0,04418764 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01683942 0,04414023 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01683942 0,04409292 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01683942 0,04404571 ! reproductive behavior GO:0019098 22 9 0,000 0,01683942 0,0439986 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01683942 0,0439516 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01683942 0,04390469 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01683942 0,04385788 ! UTP metabolic process GO:0046051 10 9 0,000 0,01683942 0,04381118 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01683942 0,04376457 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01683942 0,04371806 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01683942 0,04367165 ! artery development GO:0060840 25 9 0,000 0,01683942 0,04362534 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01683942 0,04357912 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01683942 0,04353301 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01683942 0,04348699 ! equilibrioception GO:0050957 20 9 0,000 0,01683942 0,04344107 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01683942 0,04339525 ! chemosensory behavior GO:0007635 21 9 0,000 0,01683942 0,04334952 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01683942 0,04330389 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01683942 0,04325835 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01683942 0,04321291 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01683942 0,04316757 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01683942 0,04312232 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01683942 0,04307717 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01683942 0,04303211 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01683942 0,04298714 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01683942 0,04294227 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01683942 0,04289749 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01683942 0,04285281 ! protein targeting to ER GO:0045047 25 9 0,000 0,01683942 0,04280821 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01683942 0,04276371 ! T cell selection GO:0045058 27 9 0,000 0,01683942 0,04271931 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01683942 0,04267499 ! glycine catabolic process GO:0006546 15 9 0,000 0,01683942 0,04263077 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01683942 0,04258664 ! endosome organization GO:0007032 20 9 0,000 0,01683942 0,0425426 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01683942 0,04249865 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01683942 0,04245479 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01683942 0,04241102 ! mannose metabolic process GO:0006013 13 9 0,000 0,01683942 0,04236735 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01683942 0,04232376 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01683942 0,04228026 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01683942 0,04223685 ! receptor clustering GO:0043113 20 9 0,000 0,01683942 0,04219353 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01683942 0,0421503 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01683942 0,04210716 ! retinol metabolic process GO:0042572 20 9 0,000 0,01683942 0,0420641 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01683942 0,04202114 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01683942 0,04197826 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01683942 0,04193547 ! macrophage differentiation GO:0030225 15 9 0,000 0,01683942 0,04189276 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01683942 0,04185015 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01683942 0,04180762 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01683942 0,04176517 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01683942 0,04172281 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01683942 0,04168054 ! response to amine stimulus GO:0014075 13 9 0,000 0,01683942 0,04163835 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01683942 0,04159625 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01683942 0,04155424 ! erythrocyte development GO:0048821 17 9 0,000 0,01683942 0,0415123 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01683942 0,04147046 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01683942 0,04142869 ! renal water homeostasis GO:0003091 15 9 0,000 0,01683942 0,04138702 ! postreplication repair GO:0006301 25 9 0,000 0,01683942 0,04134542 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01683942 0,04130391 ! icosanoid secretion GO:0032309 15 9 0,000 0,01683942 0,04126248 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01683942 0,04122114 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01683942 0,04117987 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01683942 0,04113869 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01683942 0,0410976 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01683942 0,04105658 ! sterol catabolic process GO:0016127 14 9 0,000 0,01683942 0,04101565 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01683942 0,04097479 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01683942 0,04093402 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01683942 0,04089333 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01683942 0,04085272 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01683942 0,0408122 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01683942 0,04077175 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01683942 0,04073138 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01683942 0,04069109 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01683942 0,04065088 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01683942 0,04061075 ! purine base metabolic process GO:0006144 25 9 0,000 0,01683942 0,0405707 ! pigment granule transport GO:0051904 17 9 0,000 0,01683942 0,04053073 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01683942 0,04049084 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01683942 0,04045103 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01683942 0,04041129 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01683942 0,04037163 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01683942 0,04033205 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01683942 0,04029255 ! mitochondrion localization GO:0051646 18 9 0,000 0,01683942 0,04025312 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01869313 0,04464059 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01869313 0,04459699 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01869313 0,04455348 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01869313 0,04451006 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01869313 0,04446672 ! associative learning GO:0008306 21 10 0,000 0,01869313 0,04442346 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01869313 0,04438029 ! phosphate transport GO:0006817 24 10 0,000 0,01869313 0,0443372 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01869313 0,0442942 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01869313 0,04425128 ! CTP metabolic process GO:0046036 11 10 0,000 0,01869313 0,04420844 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01869313 0,04416569 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01869313 0,04412301 ! GTP metabolic process GO:0046039 11 10 0,000 0,01869313 0,04408042 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01869313 0,04403792 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01869313 0,04399549 ! social behavior GO:0035176 29 10 0,000 0,01869313 0,04395315 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01869313 0,04391088 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01869313 0,0438687 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01869313 0,0438266 ! androgen metabolic process GO:0008209 17 10 0,000 0,01869313 0,04378458 ! phospholipid efflux GO:0033700 19 10 0,000 0,01869313 0,04374264 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01869313 0,04370078 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01869313 0,043659 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01869313 0,04361731 ! lung alveolus development GO:0048286 26 10 0,000 0,01869313 0,04357569 ! pathogenesis GO:0009405 17 10 0,000 0,01869313 0,04353415 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01869313 0,04349268 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01869313 0,0434513 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01869313 0,04341 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01869313 0,04336877 ! endoderm development GO:0007492 18 10 0,000 0,01869313 0,04332763 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01869313 0,04328656 ! arginine catabolic process GO:0006527 17 10 0,000 0,01869313 0,04324557 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01869313 0,04320465 ! proline metabolic process GO:0006560 13 10 0,000 0,01869313 0,04316382 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01869313 0,04312306 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01869313 0,04308238 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01869313 0,04304177 ! V(D)J recombination GO:0033151 34 10 0,000 0,01869313 0,04300124 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01869313 0,04296079 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01869313 0,04292041 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01869313 0,04288011 ! B cell proliferation GO:0042100 19 10 0,000 0,01869313 0,04283989 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01869313 0,04279974 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01869313 0,04275966 ! multicellular organism growth GO:0035264 19 10 0,000 0,01869313 0,04271966 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01869313 0,04267974 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01869313 0,04263989 ! ruffle organization GO:0031529 17 10 0,000 0,01869313 0,04260011 ! epithelial cell development GO:0002064 21 10 0,000 0,01869313 0,04256041 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01869313 0,04252078 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01869313 0,04248123 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01869313 0,04244175 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01869313 0,04240234 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01869313 0,042363 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01869313 0,04232374 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01869313 0,04228455 ! motor axon guidance GO:0008045 22 10 0,000 0,01869313 0,04224544 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01869313 0,04220639 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01869313 0,04216742 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01869313 0,04212852 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01869313 0,04208969 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01869313 0,04205094 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01869313 0,04201225 ! segment specification GO:0007379 15 10 0,000 0,01869313 0,04197364 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01869313 0,0419351 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01869313 0,04189662 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01869313 0,04185822 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01869313 0,04181989 ! response to dsRNA GO:0043331 23 10 0,000 0,01869313 0,04178163 ! DNA ligation GO:0006266 18 10 0,000 0,01869313 0,04174344 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01869313 0,04170531 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01869313 0,04166726 ! melanosome localization GO:0032400 16 10 0,000 0,01869313 0,04162928 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01869313 0,04159137 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01869313 0,04155352 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01869313 0,04151574 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01869313 0,04147804 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01869313 0,0414404 ! induction of an organ GO:0001759 17 10 0,000 0,01869313 0,04140283 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01869313 0,04136533 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01869313 0,04132789 ! protein sumoylation GO:0016925 17 10 0,000 0,01869313 0,04129052 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01869313 0,04125322 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01869313 0,04121599 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01869313 0,04117883 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01869313 0,04114173 ! salivary gland development GO:0007431 28 10 0,000 0,01869313 0,0411047 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01869313 0,04106773 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01869313 0,04103083 ! midbrain development GO:0030901 14 10 0,000 0,01869313 0,040994 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01869313 0,04095724 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01869313 0,04092054 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01869313 0,0408839 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01869313 0,04084733 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01869313 0,04081083 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01869313 0,04077439 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01869313 0,04073802 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01869313 0,04070171 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01869313 0,04066547 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01869313 0,04062929 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01869313 0,04059317 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01869313 0,04055712 ! blastocyst formation GO:0001825 18 10 0,000 0,01869313 0,04052113 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01869313 0,04048521 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01869313 0,04044935 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01869313 0,04041356 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01869313 0,04037782 ! response to nicotine GO:0035094 20 10 0,000 0,01869313 0,04034215 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01869313 0,04030655 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01869313 0,040271 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0205434 0,04421809 ! respiratory burst GO:0045730 17 11 0,000 0,0205434 0,04417917 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0205434 0,04414031 ! neuron fate specification GO:0048665 18 11 0,000 0,0205434 0,04410152 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0205434 0,0440628 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0205434 0,04402415 ! thyroid gland development GO:0030878 26 11 0,000 0,0205434 0,04398557 ! synapsis GO:0007129 14 11 0,000 0,0205434 0,04394705 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0205434 0,0439086 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0205434 0,04387022 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,0205434 0,04383191 ! response to pain GO:0048265 27 11 0,000 0,0205434 0,04379366 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0205434 0,04375548 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0205434 0,04371736 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0205434 0,04367932 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,0205434 0,04364133 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,0205434 0,04360342 ! bone resorption GO:0045453 16 11 0,000 0,0205434 0,04356557 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0205434 0,04352778 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0205434 0,04349006 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0205434 0,04345241 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0205434 0,04341482 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0205434 0,0433773 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0205434 0,04333984 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0205434 0,04330244 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0205434 0,04326511 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,0205434 0,04322785 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0205434 0,04319065 ! UV protection GO:0009650 20 11 0,000 0,0205434 0,04315351 ! adult heart development GO:0007512 16 11 0,000 0,0205434 0,04311644 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0205434 0,04307943 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0205434 0,04304248 ! macroautophagy GO:0016236 19 11 0,000 0,0205434 0,0430056 ! temperature homeostasis GO:0001659 18 11 0,000 0,0205434 0,04296878 ! behavioral fear response GO:0001662 27 11 0,000 0,0205434 0,04293202 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0205434 0,04289533 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0205434 0,0428587 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0205434 0,04282213 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0205434 0,04278562 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0205434 0,04274918 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0205434 0,04271279 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0205434 0,04267647 ! regulation of organ growth GO:0046620 14 11 0,000 0,0205434 0,04264022 ! pigment granule localization GO:0051875 20 11 0,000 0,0205434 0,04260402 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0205434 0,04256788 ! vasoconstriction GO:0042310 20 11 0,000 0,0205434 0,04253181 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0205434 0,04249579 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0205434 0,04245984 ! embryonic axis specification GO:0000578 19 11 0,000 0,0205434 0,04242395 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0205434 0,04238812 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0205434 0,04235235 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0205434 0,04231664 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0205434 0,04228099 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0205434 0,0422454 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0205434 0,04220987 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0205434 0,0421744 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0205434 0,04213899 ! prophase GO:0051324 17 11 0,000 0,0205434 0,04210364 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0205434 0,04206834 ! nucleosome positioning GO:0016584 15 11 0,000 0,0205434 0,04203311 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0205434 0,04199794 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0205434 0,04196282 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0205434 0,04192776 ! apical protein localization GO:0045176 18 11 0,000 0,0205434 0,04189277 ! acid secretion GO:0046717 20 11 0,000 0,0205434 0,04185783 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0205434 0,04182294 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0205434 0,04178812 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,0205434 0,04175336 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0205434 0,04171865 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0205434 0,041684 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0205434 0,04164941 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,0205434 0,04161487 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0205434 0,04158039 ! oocyte development GO:0048599 20 11 0,000 0,0205434 0,04154597 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0205434 0,04151161 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0205434 0,0414773 ! embryonic gut development GO:0048566 19 11 0,000 0,0205434 0,04144305 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0205434 0,04140886 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0205434 0,04137472 ! activation of innate immune response GO:0002218 16 11 0,000 0,0205434 0,04134064 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0205434 0,04130661 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0205434 0,04127264 ! lysogeny GO:0030069 22 11 0,000 0,0205434 0,04123873 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0205434 0,04120487 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0205434 0,04117107 ! regulation of embryonic development GO:0045995 35 11 0,000 0,0205434 0,04113732 ! nucleus localization GO:0051647 22 11 0,000 0,0205434 0,04110363 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02239024 0,04476215 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02239024 0,04472555 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02239024 0,04468901 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02239024 0,04465253 ! virus-host interaction GO:0019048 30 12 0,000 0,02239024 0,04461611 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02239024 0,04457975 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02239024 0,04454345 ! protein complex disassembly GO:0043241 28 12 0,000 0,02239024 0,0445072 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02239024 0,04447102 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02239024 0,04443489 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02239024 0,04439882 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02239024 0,04436282 ! T cell proliferation GO:0042098 32 12 0,000 0,02239024 0,04432686 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02239024 0,04429097 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02239024 0,04425514 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02239024 0,04421936 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02239024 0,04418364 ! drug transport GO:0015893 16 12 0,000 0,02239024 0,04414798 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02239024 0,04411238 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02239024 0,04407683 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02239024 0,04404135 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02239024 0,04400591 ! focal adhesion formation GO:0048041 37 12 0,000 0,02239024 0,04397054 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02239024 0,04393522 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02239024 0,04389996 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02239024 0,04386476 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02239024 0,04382961 ! lipid digestion GO:0044241 21 12 0,000 0,02239024 0,04379452 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02239024 0,04375948 ! entry into host cell GO:0030260 34 12 0,000 0,02239024 0,0437245 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02239024 0,04368958 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02239024 0,04365471 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02239024 0,0436199 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02239024 0,04358514 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02239024 0,04355044 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02239024 0,04351579 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02239024 0,0434812 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02239024 0,04344667 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02239024 0,04341218 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02239024 0,04337776 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02239024 0,04334338 ! cranial nerve development GO:0021545 23 12 0,000 0,02239024 0,04330907 ! fucose catabolic process GO:0019317 25 12 0,000 0,02239024 0,0432748 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02239024 0,04324059 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02239024 0,04320644 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02239024 0,04317234 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02239024 0,04313829 ! zymogen activation GO:0031638 18 12 0,000 0,02239024 0,0431043 ! T cell homeostasis GO:0043029 28 12 0,000 0,02239024 0,04307036 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02239024 0,04303647 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02239024 0,04300263 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02239024 0,04296885 ! oocyte differentiation GO:0009994 21 12 0,000 0,02239024 0,04293513 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02239024 0,04290145 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02239024 0,04286783 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02239024 0,04283426 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02239024 0,04280074 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02239024 0,04276728 ! defense response to fungus GO:0050832 15 12 0,000 0,02239024 0,04273387 ! developmental induction GO:0031128 22 12 0,000 0,02239024 0,04270051 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02239024 0,0426672 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02239024 0,04263394 ! response to cold GO:0009409 17 12 0,000 0,02239024 0,04260074 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02239024 0,04256759 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02239024 0,04253449 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02423364 0,04600061 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02423364 0,0459649 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02423364 0,04592924 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02423364 0,04589363 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02423364 0,04585809 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02423364 0,04582259 ! peroxisomal transport GO:0043574 28 13 0,000 0,02423364 0,04578715 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02423364 0,04575177 ! cartilage condensation GO:0001502 22 13 0,000 0,02423364 0,04571644 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02423364 0,04568116 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02423364 0,04564594 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02423364 0,04561078 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02423364 0,04557566 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02423364 0,04554061 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02423364 0,0455056 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02423364 0,04547065 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02423364 0,04543576 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02423364 0,04540091 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02423364 0,04536612 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02423364 0,04533139 ! methionine metabolic process GO:0006555 31 13 0,000 0,02423364 0,0452967 ! plasma membrane organization GO:0007009 27 13 0,000 0,02423364 0,04526207 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02423364 0,04522749 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02423364 0,04519297 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02423364 0,0451585 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02423364 0,04512408 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02423364 0,04508971 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02423364 0,04505539 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02423364 0,04502113 ! exocrine system development GO:0035272 34 13 0,000 0,02423364 0,04498692 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02423364 0,04495276 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02423364 0,04491866 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02423364 0,0448846 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02423364 0,0448506 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02423364 0,04481665 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02423364 0,04478274 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02423364 0,0447489 ! protein homotetramerization GO:0051289 24 13 0,000 0,02423364 0,0447151 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02423364 0,04468135 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02423364 0,04464765 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02423364 0,04461401 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02423364 0,04458041 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02423364 0,04454687 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02423364 0,04451338 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02423364 0,04447993 ! histone methylation GO:0016571 29 13 0,000 0,02423364 0,04444654 ! chromatin silencing GO:0006342 29 13 0,000 0,02423364 0,04441319 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02423364 0,0443799 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02423364 0,04434666 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02423364 0,04431346 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02423364 0,04428032 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02423364 0,04424723 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02423364 0,04421418 ! spleen development GO:0048536 24 13 0,000 0,02423364 0,04418119 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02423364 0,04414824 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02423364 0,04411534 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02423364 0,04408249 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02423364 0,04404969 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02423364 0,04401694 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02423364 0,04398424 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02423364 0,04395159 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02423364 0,04391898 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02423364 0,04388643 ! insulin secretion GO:0030073 24 13 0,000 0,02423364 0,04385392 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02423364 0,04382146 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02423364 0,04378904 ! acrosome reaction GO:0007340 19 13 0,000 0,02423364 0,04375668 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02423364 0,04372436 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02423364 0,0436921 ! rRNA transcription GO:0009303 28 14 0,000 0,02607362 0,04697482 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02607362 0,04694021 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02607362 0,04690564 ! water transport GO:0006833 21 14 0,000 0,02607362 0,04687113 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02607362 0,04683666 ! non-recombinational repair GO:0000726 29 14 0,000 0,02607362 0,04680225 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02607362 0,04676789 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02607362 0,04673357 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02607362 0,04669931 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02607362 0,0466651 ! palate development GO:0060021 32 14 0,000 0,02607362 0,04663094 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02607362 0,04659683 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02607362 0,04656276 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02607362 0,04652875 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02607362 0,04649479 ! arginine metabolic process GO:0006525 21 14 0,000 0,02607362 0,04646088 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02607362 0,04642701 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02607362 0,0463932 ! regulation of heart rate GO:0002027 25 14 0,000 0,02607362 0,04635943 ! fear response GO:0042596 34 14 0,000 0,02607362 0,04632572 ! organic alcohol transport GO:0015850 29 14 0,000 0,02607362 0,04629205 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02607362 0,04625843 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02607362 0,04622486 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02607362 0,04619134 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02607362 0,04615787 ! bone mineralization GO:0030282 18 14 0,000 0,02607362 0,04612445 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02607362 0,04609107 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02607362 0,04605774 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02607362 0,04602447 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02607362 0,04599124 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02607362 0,04595805 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02607362 0,04592492 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02607362 0,04589183 ! ribosome assembly GO:0042255 18 14 0,000 0,02607362 0,04585879 ! cerebellum development GO:0021549 23 14 0,000 0,02607362 0,0458258 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02607362 0,04579285 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02607362 0,04575996 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02607362 0,04572711 ! response to gamma radiation GO:0010332 30 14 0,000 0,02607362 0,0456943 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02607362 0,04566155 ! NADP metabolic process GO:0006739 24 14 0,000 0,02607362 0,04562884 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02607362 0,04559618 ! oxygen transport GO:0015671 22 14 0,000 0,02607362 0,04556356 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02607362 0,04553099 ! male genitalia development GO:0030539 26 14 0,000 0,02607362 0,04549847 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02607362 0,045466 ! regulation of axon extension GO:0030516 43 14 0,000 0,02607362 0,04543357 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02607362 0,04540118 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02607362 0,04536885 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02791019 0,04852995 ! lactation GO:0007595 30 15 0,000 0,02791019 0,04849544 ! reproductive cellular process GO:0048610 22 15 0,000 0,02791019 0,04846097 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02791019 0,04842655 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02791019 0,04839218 ! superoxide anion generation GO:0042554 22 15 0,000 0,02791019 0,04835786 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02791019 0,04832359 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02791019 0,04828937 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02791019 0,04825519 ! copper ion transport GO:0006825 22 15 0,000 0,02791019 0,04822106 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02791019 0,04818698 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02791019 0,04815295 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02791019 0,04811897 ! sulfate transport GO:0008272 27 15 0,000 0,02791019 0,04808504 ! response to cAMP GO:0051591 25 15 0,000 0,02791019 0,04805115 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02791019 0,04801731 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02791019 0,04798352 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02791019 0,04794978 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02791019 0,04791608 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02791019 0,04788243 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02791019 0,04784883 ! vesicle coating GO:0006901 38 15 0,000 0,02791019 0,04781528 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02791019 0,04778177 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02791019 0,04774831 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02791019 0,04771489 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02791019 0,04768153 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02791019 0,04764821 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02791019 0,04761493 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02791019 0,04758171 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02791019 0,04754852 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02791019 0,04751539 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02791019 0,0474823 ! histone deacetylation GO:0016575 24 15 0,000 0,02791019 0,04744926 ! water homeostasis GO:0030104 28 15 0,000 0,02791019 0,04741626 ! cofactor transport GO:0051181 30 15 0,000 0,02791019 0,04738331 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02791019 0,04735041 ! muscle maintenance GO:0046716 26 15 0,000 0,02791019 0,04731755 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02791019 0,04728473 ! intestinal absorption GO:0050892 31 15 0,000 0,02791019 0,04725196 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02791019 0,04721924 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02791019 0,04718656 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02791019 0,04715393 ! cell killing GO:0001906 32 15 0,000 0,02791019 0,04712134 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02791019 0,0470888 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02791019 0,0470563 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02791019 0,04702385 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02791019 0,04699144 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02791019 0,04695908 ! actin filament polymerization GO:0030041 27 15 0,000 0,02791019 0,04692676 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02791019 0,04689449 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02974334 0,04994019 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02974334 0,04990589 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02974334 0,04987163 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02974334 0,04983743 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02974334 0,04980327 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02974334 0,04976916 ! bone remodeling GO:0046849 28 16 0,000 0,02974334 0,04973509 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02974334 0,04970107 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02974334 0,0496671 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02974334 0,04963318 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02974334 0,0495993 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02974334 0,04956546 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02974334 0,04953168 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02974334 0,04949794 ! startle response GO:0001964 28 16 0,000 0,02974334 0,04946424 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02974334 0,04943059 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02974334 0,04939699 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02974334 0,04936343 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02974334 0,04932992 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02974334 0,04929645 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02974334 0,04926303 ! pituitary gland development GO:0021983 30 16 0,000 0,02974334 0,04922966 ! response to osmotic stress GO:0006970 27 16 0,000 0,02974334 0,04919632 ! lysosomal transport GO:0007041 31 16 0,000 0,02974334 0,04916304 ! fructose metabolic process GO:0006000 25 16 0,000 0,02974334 0,0491298 ! L-amino acid transport GO:0015807 33 16 0,000 0,02974334 0,0490966 ! stem cell development GO:0048864 46 16 0,000 0,02974334 0,04906345 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02974334 0,04903034 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,02974334 0,04899728 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02974334 0,04896427 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02974334 0,04893129 ! axon cargo transport GO:0008088 46 16 0,000 0,02974334 0,04889837 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02974334 0,04886548 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02974334 0,04883264 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,02974334 0,04879985 ! DNA replication initiation GO:0006270 28 16 0,000 0,02974334 0,04876709 ! neuron recognition GO:0008038 40 16 0,000 0,02974334 0,04873439 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02974334 0,04870172 ! tissue regeneration GO:0042246 27 16 0,000 0,02974334 0,0486691 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02974334 0,04863653 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02974334 0,04860399 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02974334 0,0485715 ! biomineral formation GO:0031214 22 16 0,000 0,02974334 0,04853906 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02974334 0,04850666 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02974334 0,0484743 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02974334 0,04844198 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02974334 0,04840971 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02974334 0,04837748 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02974334 0,04834529 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02974334 0,04831315 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02974334 0,04828104 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02974334 0,04824898 ! peptide hormone processing GO:0016486 27 16 0,000 0,02974334 0,04821697 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03157308 0,05114923 ! metencephalon development GO:0022037 32 17 0,000 0,03157308 0,05111533 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03157308 0,05108148 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03157308 0,05104768 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03157308 0,05101391 ! filopodium assembly GO:0046847 42 17 0,000 0,03157308 0,0509802 ! endothelial cell migration GO:0043542 31 17 0,000 0,03157308 0,05094653 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03157308 0,0509129 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03157308 0,05087931 ! glial cell development GO:0021782 28 17 0,000 0,03157308 0,05084577 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03157308 0,05081228 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03157308 0,05077883 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03157308 0,05074542 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03157308 0,05071206 ! myoblast differentiation GO:0045445 50 17 0,000 0,03157308 0,05067874 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03157308 0,05064546 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03157308 0,05061223 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03157308 0,05057904 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03157308 0,0505459 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03157308 0,0505128 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03157308 0,05047974 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03157308 0,05044672 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03157308 0,05041375 ! membrane budding GO:0006900 42 17 0,000 0,03157308 0,05038082 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03157308 0,05034794 ! regulation of protein binding GO:0043393 33 17 0,000 0,03157308 0,05031509 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03157308 0,05028229 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03157308 0,05024954 ! genitalia development GO:0048806 32 17 0,000 0,03157308 0,05021682 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03157308 0,05018415 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03157308 0,05015152 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03157308 0,05011893 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03157308 0,05008639 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03157308 0,05005389 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03157308 0,05002143 ! steroid catabolic process GO:0006706 34 17 0,000 0,03157308 0,04998901 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03157308 0,04995663 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03157308 0,0499243 ! gas transport GO:0015669 26 17 0,000 0,03157308 0,049892 ! organic cation transport GO:0015695 32 17 0,000 0,03157308 0,04985975 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03157308 0,04982754 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03157308 0,04979538 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03339943 0,05264181 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03339943 0,05260787 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03339943 0,05257397 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03339943 0,05254012 ! adult walking behavior GO:0007628 36 18 0,000 0,03339943 0,05250631 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03339943 0,05247254 ! heart looping GO:0001947 34 18 0,000 0,03339943 0,05243882 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03339943 0,05240514 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03339943 0,0523715 ! centrosome cycle GO:0007098 26 18 0,000 0,03339943 0,05233791 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03339943 0,05230436 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03339943 0,05227085 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03339943 0,05223739 ! glycine metabolic process GO:0006544 30 18 0,000 0,03339943 0,05220397 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03339943 0,05217059 ! response to retinoic acid GO:0032526 31 18 0,000 0,03339943 0,05213725 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03339943 0,05210396 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03339943 0,05207071 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03339943 0,0520375 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03339943 0,05200434 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03339943 0,05197121 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03339943 0,05193813 ! neural crest cell migration GO:0001755 41 18 0,000 0,03339943 0,05190509 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03339943 0,05187209 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03339943 0,05183914 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03339943 0,05180622 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03339943 0,05177335 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03339943 0,05174052 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03339943 0,05170773 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03339943 0,05167499 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03339943 0,05164228 ! detection of bacterium GO:0016045 22 18 0,000 0,03339943 0,05160962 ! nerve development GO:0021675 34 18 0,000 0,03339943 0,05157699 ! defense response to virus GO:0051607 43 18 0,000 0,03339943 0,05154441 ! microspike assembly GO:0030035 46 18 0,000 0,03339943 0,05151187 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03339943 0,05147937 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03339943 0,05144691 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03522238 0,05422072 ! positive regulation of translation GO:0045727 31 19 0,000 0,03522238 0,05418657 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03522238 0,05415247 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03522238 0,05411841 ! neuron maturation GO:0042551 46 19 0,000 0,03522238 0,0540844 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03522238 0,05405043 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03522238 0,0540165 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03522238 0,05398261 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03522238 0,05394876 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03522238 0,05391496 ! inositol metabolic process GO:0006020 33 19 0,000 0,03522238 0,0538812 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03522238 0,05384748 ! memory GO:0007613 34 19 0,000 0,03522238 0,05381381 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03522238 0,05378017 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03522238 0,05374658 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03522238 0,05371303 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03522238 0,05367952 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03522238 0,05364606 ! pigmentation during development GO:0048066 42 19 0,000 0,03522238 0,05361263 ! response to vitamin A GO:0033189 32 19 0,000 0,03522238 0,05357925 ! heme metabolic process GO:0042168 40 19 0,000 0,03522238 0,05354591 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03522238 0,05351261 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03522238 0,05347935 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03522238 0,05344614 ! response to fungus GO:0009620 26 19 0,000 0,03522238 0,05341296 ! peptide cross-linking GO:0018149 39 19 0,000 0,03522238 0,05337983 ! protein export from nucleus GO:0006611 40 19 0,000 0,03522238 0,05334673 ! heart process GO:0003015 32 19 0,000 0,03522238 0,05331368 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03522238 0,05328067 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03522238 0,0532477 ! visual learning GO:0008542 38 19 0,000 0,03522238 0,05321477 ! cellular pigmentation GO:0033059 37 19 0,000 0,03522238 0,05318188 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03522238 0,05314903 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03522238 0,05311622 ! vitamin transport GO:0051180 31 19 0,000 0,03522238 0,05308345 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03522238 0,05305073 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03522238 0,05301804 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03522238 0,05298539 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03522238 0,05295279 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03522238 0,05292022 ! cilium assembly GO:0042384 38 19 0,000 0,03522238 0,05288769 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03522238 0,05285521 ! protein secretion GO:0009306 45 20 0,000 0,03704195 0,05555155 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03704195 0,05551747 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03704195 0,05548343 ! positive regulation of ossification GO:0045778 50 20 0,000 0,03704195 0,05544944 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03704195 0,05541548 ! skin development GO:0043588 42 20 0,000 0,03704195 0,05538157 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03704195 0,05534769 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03704195 0,05531386 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,03704195 0,05528007 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03704195 0,05524632 ! response to vitamin GO:0033273 36 20 0,000 0,03704195 0,05521262 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03704195 0,05517895 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,03704195 0,05514533 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03704195 0,05511174 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03704195 0,0550782 ! response to alkaloid GO:0043279 38 20 0,000 0,03704195 0,0550447 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03704195 0,05501123 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,03704195 0,05497781 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,03704195 0,05494443 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03704195 0,05491109 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03704195 0,05487779 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03704195 0,05484453 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,03704195 0,05481131 ! body fluid secretion GO:0007589 33 20 0,000 0,03704195 0,05477813 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03704195 0,054745 ! peptide secretion GO:0002790 38 20 0,000 0,03704195 0,0547119 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03704195 0,05467884 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03704195 0,05464582 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03704195 0,05461284 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03704195 0,0545799 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03704195 0,054547 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03704195 0,05451414 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03704195 0,05448132 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03704195 0,05444854 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,03704195 0,0544158 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03704195 0,0543831 ! regulation of glucose import GO:0046324 30 20 0,000 0,03704195 0,05435044 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03704195 0,05431781 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03704195 0,05428523 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03704195 0,05425269 ! negative regulation of translation GO:0017148 32 20 0,000 0,03704195 0,05422018 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03704195 0,05418771 ! regulation of cell killing GO:0031341 46 21 0,000 0,03885813 0,05681055 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,03885813 0,05677657 ! hormone secretion GO:0046879 39 21 0,000 0,03885813 0,05674263 ! cAMP metabolic process GO:0046058 41 21 0,000 0,03885813 0,05670873 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,03885813 0,05667488 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,03885813 0,05664106 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,03885813 0,05660729 ! ovarian follicle development GO:0001541 39 21 0,000 0,03885813 0,05657355 ! smooth muscle contraction GO:0006939 48 21 0,000 0,03885813 0,05653986 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,03885813 0,0565062 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,03885813 0,05647259 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,03885813 0,05643901 ! plasma membrane fusion GO:0045026 33 21 0,000 0,03885813 0,05640548 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,03885813 0,05637198 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,03885813 0,05633853 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,03885813 0,05630511 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,03885813 0,05627174 ! diencephalon development GO:0021536 36 21 0,000 0,03885813 0,0562384 ! collagen fibril organization GO:0030199 62 21 0,000 0,03885813 0,0562051 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,03885813 0,05617185 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,03885813 0,05613863 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,03885813 0,05610545 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,03885813 0,05607231 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,03885813 0,05603921 ! collagen catabolic process GO:0030574 29 21 0,000 0,03885813 0,05600615 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,03885813 0,05597313 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,03885813 0,05594014 ! sperm-egg recognition GO:0035036 23 21 0,000 0,03885813 0,0559072 ! actin filament-based movement GO:0030048 47 21 0,000 0,03885813 0,05587429 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,03885813 0,05584142 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04067095 0,05841218 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04067095 0,05837786 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04067095 0,05834358 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04067095 0,05830934 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04067095 0,05827514 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04067095 0,05824098 ! microtubule-based transport GO:0010970 59 22 0,000 0,04067095 0,05820687 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04067095 0,05817279 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04067095 0,05813875 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04067095 0,05810475 ! cellular response to starvation GO:0009267 37 22 0,000 0,04067095 0,05807079 ! vacuolar transport GO:0007034 41 22 0,000 0,04067095 0,05803687 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04067095 0,05800299 ! fucose metabolic process GO:0006004 44 22 0,000 0,04067095 0,05796915 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04067095 0,05793535 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04067095 0,05790158 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04067095 0,05786786 ! ureteric bud development GO:0001657 50 22 0,000 0,04067095 0,05783418 ! cell aging GO:0007569 48 22 0,000 0,04067095 0,05780054 ! stem cell differentiation GO:0048863 57 22 0,000 0,04067095 0,05776693 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04067095 0,05773336 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04067095 0,05769984 ! cytolysis GO:0019835 27 22 0,000 0,04067095 0,05766635 ! renal system process GO:0003014 42 22 0,000 0,04067095 0,0576329 ! vasodilation GO:0042311 40 22 0,000 0,04067095 0,05759949 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04067095 0,05756612 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04067095 0,05753279 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,04067095 0,05749949 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04067095 0,05746623 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04067095 0,05743302 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,04067095 0,05739984 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04067095 0,0573667 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04067095 0,05733359 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04067095 0,05730053 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04067095 0,0572675 ! sarcomere organization GO:0045214 32 22 0,000 0,04067095 0,05723452 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04067095 0,05720157 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04067095 0,05716865 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04067095 0,05713578 ! gut development GO:0048565 44 22 0,000 0,04067095 0,05710294 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04067095 0,05707014 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04067095 0,05703738 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04067095 0,05700466 ! protein stabilization GO:0050821 41 22 0,000 0,04067095 0,05697197 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04248039 0,05947254 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04248039 0,05943848 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04248039 0,05940446 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04248039 0,05937047 ! gluconeogenesis GO:0006094 38 23 0,000 0,04248039 0,05933653 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04248039 0,05930262 ! viral genome replication GO:0019079 44 23 0,000 0,04248039 0,05926875 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04248039 0,05923493 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04248039 0,05920114 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04248039 0,05916738 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04248039 0,05913367 ! regeneration GO:0031099 42 23 0,000 0,04248039 0,05909999 ! axis specification GO:0009798 43 23 0,000 0,04248039 0,05906636 ! visual behavior GO:0007632 46 23 0,000 0,04248039 0,05903276 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04248039 0,0589992 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04248039 0,05896568 ! response to ethanol GO:0045471 47 23 0,000 0,04248039 0,05893219 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04248039 0,05889875 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04248039 0,05886534 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04248039 0,05883197 ! peroxisome organization GO:0007031 43 23 0,000 0,04248039 0,05879863 ! lysosome organization GO:0007040 47 23 0,000 0,04248039 0,05876534 ! vesicle targeting GO:0006903 49 23 0,000 0,04248039 0,05873208 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04248039 0,05869886 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04248039 0,05866568 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04248039 0,05863254 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04248039 0,05859943 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04248039 0,05856636 ! DNA modification GO:0006304 36 23 0,000 0,04248039 0,05853333 ! fatty acid transport GO:0015908 47 23 0,000 0,04248039 0,05850033 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04248039 0,05846737 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04248039 0,05843445 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04248039 0,05840157 ! hormone transport GO:0009914 41 23 0,000 0,04248039 0,05836872 ! cell-cell recognition GO:0009988 28 23 0,000 0,04248039 0,05833591 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04248039 0,05830314 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04248039 0,0582704 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04248039 0,0582377 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,04428647 0,06067967 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,04428647 0,06064565 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,04428647 0,06061168 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,04428647 0,06057774 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,04428647 0,06054384 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,04428647 0,06050998 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,04428647 0,06047616 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,04428647 0,06044237 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,04428647 0,06040862 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,04428647 0,06037491 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,04428647 0,06034124 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,04428647 0,06030761 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,04428647 0,06027401 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,04428647 0,06024045 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,04428647 0,06020693 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,04428647 0,06017344 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,04428647 0,06013999 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,04428647 0,06010658 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,04428647 0,06007321 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,04428647 0,06003987 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,04428647 0,06000657 ! oogenesis GO:0048477 44 24 0,000 0,04428647 0,05997331 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,04428647 0,05994008 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,04428647 0,05990689 ! platelet activation GO:0030168 41 24 0,000 0,04428647 0,05987374 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,04428647 0,05984062 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,04428647 0,05980754 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,04428647 0,0597745 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,04428647 0,05974149 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,04428647 0,05970852 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,04428647 0,05967559 ! regulation of amine transport GO:0051952 41 24 0,000 0,04428647 0,05964269 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0460892 0,06203631 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0460892 0,06200215 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0460892 0,06196803 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0460892 0,06193394 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0460892 0,06189989 ! phototransduction GO:0007602 37 25 0,000 0,0460892 0,06186588 ! keratinization GO:0031424 37 25 0,000 0,0460892 0,06183191 ! vacuole organization GO:0007033 49 25 0,000 0,0460892 0,06179797 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0460892 0,06176407 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0460892 0,06173021 ! receptor metabolic process GO:0043112 53 25 0,000 0,0460892 0,06169639 ! chromosome condensation GO:0030261 48 25 0,000 0,0460892 0,0616626 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0460892 0,06162885 ! regulation of behavior GO:0050795 48 25 0,000 0,0460892 0,06159513 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0460892 0,06156146 ! interaction with host GO:0051701 66 25 0,000 0,0460892 0,06152782 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0460892 0,06149421 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0460892 0,06146065 ! immunoglobulin production GO:0002377 62 25 0,000 0,0460892 0,06142712 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0460892 0,06139362 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0460892 0,06136017 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0460892 0,06132675 ! liver development GO:0001889 55 25 0,000 0,0460892 0,06129336 ! protein tetramerization GO:0051262 57 25 0,000 0,0460892 0,06126001 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,04788857 0,06361706 ! myelination GO:0042552 50 26 0,000 0,04788857 0,06358249 ! initiation of viral infection GO:0019059 60 26 0,000 0,04788857 0,06354795 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,04788857 0,06351345 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,04788857 0,06347899 ! molting cycle process GO:0022404 52 26 0,000 0,04788857 0,06344457 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,04788857 0,06341018 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,04788857 0,06337583 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,04788857 0,06334152 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,04788857 0,06330724 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,04788857 0,063273 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,04788857 0,0632388 ! digestive system process GO:0022600 49 26 0,000 0,04788857 0,06320464 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,04788857 0,06317051 ! osteoblast differentiation GO:0001649 63 26 0,000 0,04788857 0,06313642 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,04788857 0,06310236 ! neural crest cell development GO:0014032 59 26 0,000 0,04788857 0,06306834 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,04788857 0,06303436 ! negative regulation of cell development GO:0010721 83 26 0,000 0,04788857 0,06300042 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,04788857 0,06296651 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,04788857 0,06293264 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,04788857 0,06289881 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,04788857 0,06286501 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,04788857 0,06283125 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,04788857 0,06279752 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,04788857 0,06276383 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,04788857 0,06273018 ! blastocyst development GO:0001824 50 26 0,000 0,04788857 0,06269656 ! telomere organization GO:0032200 46 26 0,000 0,04788857 0,06266298 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,04788857 0,06262943 ! neural tube closure GO:0001843 58 26 0,000 0,04788857 0,06259592 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,04788857 0,06256245 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,04788857 0,06252901 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0496846 0,06483947 ! embryonic pattern specification GO:0009880 49 27 0,000 0,0496846 0,06480485 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,0496846 0,06477027 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,0496846 0,06473573 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,0496846 0,06470122 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,0496846 0,06466675 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,0496846 0,06463231 ! iron ion transport GO:0006826 65 27 0,000 0,0496846 0,06459792 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,0496846 0,06456356 ! superoxide metabolic process GO:0006801 41 27 0,000 0,0496846 0,06452923 ! tube lumen formation GO:0035148 59 27 0,000 0,0496846 0,06449494 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,0496846 0,06446069 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,0496846 0,06442648 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,0496846 0,0643923 ! response to starvation GO:0042594 47 27 0,000 0,0496846 0,06435816 ! response to toxin GO:0009636 49 27 0,000 0,0496846 0,06432405 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,0496846 0,06428998 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,0496846 0,06425595 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,0496846 0,06422195 ! leukocyte proliferation GO:0070661 59 27 0,000 0,0496846 0,06418799 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,0496846 0,06415406 ! neuron fate commitment GO:0048663 52 28 0,000 0,0514773 0,06643372 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,0514773 0,06639865 ! circadian rhythm GO:0007623 56 28 0,000 0,0514773 0,06636361 ! dendrite development GO:0016358 67 28 0,000 0,0514773 0,06632861 ! fat cell differentiation GO:0045444 57 28 0,000 0,0514773 0,06629364 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,0514773 0,06625871 ! sperm motility GO:0030317 37 28 0,000 0,0514773 0,06622382 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,0514773 0,06618897 ! base-excision repair GO:0006284 41 28 0,000 0,0514773 0,06615415 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,0514773 0,06611937 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,0514773 0,06608462 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,0514773 0,06604992 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,0514773 0,06601524 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,0514773 0,06598061 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,0514773 0,06594601 ! glutathione metabolic process GO:0006749 42 28 0,000 0,0514773 0,06591145 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,0514773 0,06587692 ! lipid oxidation GO:0034440 48 28 0,000 0,0514773 0,06584243 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,0514773 0,06580797 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05326666 0,06805986 ! translational initiation GO:0006413 66 29 0,000 0,05326666 0,06802428 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05326666 0,06798874 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05326666 0,06795324 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05326666 0,06791777 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,05326666 0,06788234 ! autophagy GO:0006914 47 29 0,000 0,05326666 0,06784695 ! primary neural tube formation GO:0014020 61 29 0,000 0,05326666 0,0678116 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,05326666 0,06777628 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05326666 0,067741 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05326666 0,06770575 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,05326666 0,06767054 ! synaptogenesis GO:0007416 46 29 0,000 0,05326666 0,06763537 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05326666 0,06760024 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05326666 0,06756514 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05326666 0,06753007 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05326666 0,06749505 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0550527 0,069722 ! phenol metabolic process GO:0018958 56 30 0,000 0,0550527 0,06968588 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,0550527 0,06964979 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,0550527 0,06961374 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0550527 0,06957773 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0550527 0,06954175 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0550527 0,06950581 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0550527 0,06946991 ! acute-phase response GO:0006953 50 30 0,000 0,0550527 0,06943404 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0550527 0,06939822 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0550527 0,06936243 ! myofibril assembly GO:0030239 50 30 0,000 0,0550527 0,06932667 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0550527 0,06929095 ! cell fate determination GO:0001709 64 30 0,000 0,0550527 0,06925527 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0550527 0,06921963 ! phospholipid transport GO:0015914 65 30 0,000 0,0550527 0,06918402 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,0550527 0,06914845 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0550527 0,06911292 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0550527 0,06907742 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,0550527 0,06904196 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,0550527 0,06900654 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,05683542 0,07120458 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,05683542 0,07116808 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,05683542 0,07113162 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,05683542 0,0710952 ! cell junction assembly GO:0034329 85 31 0,000 0,05683542 0,07105882 ! regulation of innate immune response GO:0045088 57 31 0,000 0,05683542 0,07102247 ! ovulation cycle process GO:0022602 55 31 0,000 0,05683542 0,07098616 ! peptide transport GO:0015833 60 31 0,000 0,05683542 0,07094988 ! male gonad development GO:0008584 56 31 0,000 0,05683542 0,07091365 ! iron ion homeostasis GO:0055072 60 31 0,000 0,05683542 0,07087745 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,05683542 0,07084129 ! detection of light stimulus GO:0009583 44 31 0,000 0,05683542 0,07080516 ! natural killer cell activation GO:0030101 50 31 0,000 0,05683542 0,07076907 ! ensheathment of neurons GO:0007272 64 31 0,000 0,05683542 0,07073302 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,05683542 0,07069701 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,05683542 0,07066103 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,05683542 0,07062509 ! eye morphogenesis GO:0048592 65 31 0,000 0,05683542 0,07058918 ! response to heat GO:0009408 54 31 0,000 0,05683542 0,07055332 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,05683542 0,07051748 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,05861482 0,07268833 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,05861482 0,07265145 ! collagen metabolic process GO:0032963 49 32 0,000 0,05861482 0,07261461 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,05861482 0,07257781 ! spindle organization GO:0007051 50 32 0,000 0,05861482 0,07254104 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,05861482 0,07250431 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,05861482 0,07246762 ! metanephros development GO:0001656 81 32 0,000 0,05861482 0,07243096 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,05861482 0,07239434 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,05861482 0,07235776 ! muscle cell development GO:0055001 52 32 0,000 0,05861482 0,07232122 ! mesoderm formation GO:0001707 73 32 0,000 0,05861482 0,07228471 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,05861482 0,07224824 ! ovulation cycle GO:0042698 57 32 0,000 0,05861482 0,07221181 ! peripheral nervous system development GO:0007422 68 32 0,000 0,05861482 0,07217541 ! BMP signaling pathway GO:0030509 71 32 0,000 0,05861482 0,07213905 ! hindbrain development GO:0030902 65 32 0,000 0,05861482 0,07210273 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,05861482 0,07206644 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,05861482 0,07203019 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,05861482 0,07199397 ! gene silencing GO:0016458 71 32 0,000 0,05861482 0,0719578 ! regulation of pH GO:0006885 56 33 0,000 0,06039092 0,07410096 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06039092 0,07406377 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06039092 0,0740266 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06039092 0,07398948 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06039092 0,07395239 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06039092 0,07391534 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06039092 0,07387833 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06039092 0,07384135 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06039092 0,07380441 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06039092 0,07376751 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06039092 0,07373064 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06039092 0,07369382 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06039092 0,07365702 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06216372 0,07578142 ! glial cell differentiation GO:0010001 67 34 0,000 0,06216372 0,07574362 ! post-embryonic development GO:0009791 76 34 0,000 0,06216372 0,07570586 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06216372 0,07566814 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06216372 0,07563046 ! spliceosome assembly GO:0000245 75 34 0,000 0,06216372 0,07559281 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06216372 0,07555521 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,06216372 0,07551764 ! formation of primary germ layer GO:0001704 76 34 0,000 0,06216372 0,0754801 ! cell fate specification GO:0001708 56 34 0,000 0,06216372 0,07544261 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06216372 0,07540515 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06216372 0,07536772 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,06216372 0,07533034 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,06393322 0,07743622 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06393322 0,07739785 ! negative regulation of secretion GO:0051048 68 35 0,000 0,06393322 0,07735951 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,06393322 0,07732122 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,06393322 0,07728296 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06393322 0,07724474 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06393322 0,07720655 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06393322 0,07716841 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,06393322 0,0771303 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06393322 0,07709223 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,06393322 0,0770542 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06393322 0,0770162 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,06393322 0,07697824 ! placenta development GO:0001890 53 35 0,000 0,06393322 0,07694032 ! vesicle localization GO:0051648 70 35 0,000 0,06393322 0,07690244 ! regulation of muscle development GO:0048634 82 36 0,000 0,06569943 0,07898805 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,06569943 0,0789492 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,06569943 0,07891038 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,06569943 0,07887161 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,06569943 0,07883287 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,06569943 0,07879417 ! positive regulation of cell development GO:0010720 85 36 0,000 0,06569943 0,0787555 ! protein targeting to membrane GO:0006612 75 36 0,000 0,06569943 0,07871688 ! regulation of proteolysis GO:0030162 77 36 0,000 0,06569943 0,07867829 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,06569943 0,07863974 ! aerobic respiration GO:0009060 56 36 0,000 0,06569943 0,07860123 ! cytokine production GO:0001816 68 36 0,000 0,06569943 0,07856276 ! embryonic organ development GO:0048568 67 36 0,000 0,06569943 0,07852432 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,06569943 0,07848593 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,06569943 0,07844757 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,06746237 0,08051322 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,06746237 0,08047391 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,06746237 0,08043463 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,06746237 0,08039539 ! sister chromatid segregation GO:0000819 65 37 0,000 0,06746237 0,0803562 ! odontogenesis GO:0042476 74 37 0,000 0,06746237 0,08031704 ! actomyosin structure organization GO:0031032 68 37 0,000 0,06746237 0,08027791 ! cell junction organization GO:0034330 96 37 0,000 0,06746237 0,08023883 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,06746237 0,08019978 ! female gonad development GO:0008585 71 37 0,000 0,06746237 0,08016078 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,06746237 0,08012181 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,06746237 0,08008288 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,06746237 0,08004398 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,06922202 0,08209194 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,06922202 0,08205211 ! meiosis I GO:0007127 74 38 0,000 0,06922202 0,08201231 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,06922202 0,08197256 ! organic anion transport GO:0015711 82 38 0,000 0,06922202 0,08193284 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,06922202 0,08189317 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,06922202 0,08185353 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,06922202 0,08181393 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,06922202 0,08177437 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,06922202 0,08173484 ! regulation of protein stability GO:0031647 77 38 0,000 0,06922202 0,08169536 ! spermatid development GO:0007286 69 38 0,000 0,06922202 0,08165591 ! glycogen metabolic process GO:0005977 63 38 0,000 0,06922202 0,0816165 ! pigment metabolic process GO:0042440 87 38 0,000 0,06922202 0,08157713 ! neural tube formation GO:0001841 79 38 0,000 0,06922202 0,0815378 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,0709784 0,08356638 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,0709784 0,08352612 ! negative regulation of binding GO:0051100 71 39 0,000 0,0709784 0,08348591 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,0709784 0,08344573 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,0709784 0,0834056 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,0709784 0,0833655 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,0709784 0,08332544 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,0709784 0,08328542 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,0709784 0,08324543 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,0709784 0,08320549 ! glucan metabolic process GO:0044042 64 39 0,000 0,0709784 0,08316558 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,07273152 0,08517886 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07273152 0,08513805 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07273152 0,08509727 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,07273152 0,08505653 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,07273152 0,08501584 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,07273152 0,08497518 ! RNA export from nucleus GO:0006405 61 41 0,000 0,07448138 0,08697801 ! mRNA catabolic process GO:0006402 79 41 0,000 0,07448138 0,08693646 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,07448138 0,08689494 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,07448138 0,08685346 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,07448138 0,08681203 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,07448138 0,08677063 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,07448138 0,08672927 ! gliogenesis GO:0042063 91 41 0,000 0,07448138 0,08668795 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,07448138 0,08664667 ! mesenchymal cell development GO:0014031 94 41 0,000 0,07448138 0,08660543 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,07448138 0,08656423 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,07448138 0,08652307 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,07448138 0,08648194 ! spermatid differentiation GO:0048515 73 41 0,000 0,07448138 0,08644086 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,07448138 0,08639981 ! RNA modification GO:0009451 64 41 0,000 0,07448138 0,08635881 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,07622798 0,08834201 ! ear morphogenesis GO:0042471 64 42 0,000 0,07622798 0,08830013 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,07622798 0,08825828 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,07622798 0,08821647 ! T cell differentiation GO:0030217 93 42 0,000 0,07622798 0,0881747 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,07622798 0,08813297 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,07622798 0,08809128 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,07622798 0,08804963 ! regulation of protein secretion GO:0050708 77 42 0,000 0,07622798 0,08800802 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,07622798 0,08796645 ! cytokinesis GO:0000910 84 42 0,000 0,07622798 0,08792491 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,07622798 0,08788342 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,07797134 0,08985094 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,07797134 0,08980858 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,07797134 0,08976625 ! regulation of tube size GO:0035150 76 43 0,000 0,07797134 0,08972397 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,07797134 0,08968173 ! glucose transport GO:0015758 66 43 0,000 0,07797134 0,08963952 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,07797134 0,08959736 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,07797134 0,08955524 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,07797134 0,08951315 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,07797134 0,08947111 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,07797134 0,0894291 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,07797134 0,08938714 ! ion transmembrane transport GO:0034220 79 43 0,000 0,07797134 0,08934521 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,07797134 0,08930332 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,07971146 0,09125356 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,07971146 0,09121082 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,07971146 0,09116812 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,07971146 0,09112546 ! hexose transport GO:0008645 68 44 0,000 0,07971146 0,09108283 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,07971146 0,09104025 ! striated muscle contraction GO:0006941 85 44 0,000 0,07971146 0,09099771 ! phagocytosis GO:0006909 105 44 0,000 0,07971146 0,09095521 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,07971146 0,09091274 ! double-strand break repair GO:0006302 85 44 0,000 0,07971146 0,09087032 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,08144834 0,09280704 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,08144834 0,09276378 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,08144834 0,09272055 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,08144834 0,09267736 ! biopolymer methylation GO:0043414 91 45 0,000 0,08144834 0,09263422 ! B cell differentiation GO:0030183 124 45 0,000 0,08144834 0,09259111 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,08144834 0,09254805 ! female gamete generation GO:0007292 71 45 0,000 0,08144834 0,09250502 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,08144834 0,09246204 ! polyol metabolic process GO:0019751 77 45 0,000 0,08144834 0,09241909 ! developmental growth GO:0048589 88 45 0,000 0,08144834 0,09237618 ! maintenance of location in cell GO:0051651 101 45 0,000 0,08144834 0,09233332 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,083182 0,09425492 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,083182 0,09421123 ! glycolysis GO:0006096 71 46 0,000 0,083182 0,09416757 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,083182 0,09412395 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,083182 0,09408038 ! leukocyte migration GO:0050900 75 46 0,000 0,083182 0,09403684 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,083182 0,09399335 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,083182 0,09394989 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,083182 0,09390648 ! pigmentation GO:0043473 103 46 0,000 0,083182 0,0938631 ! cell growth GO:0016049 90 46 0,000 0,083182 0,09381977 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,083182 0,09377647 ! neural tube development GO:0021915 91 47 0,000 0,08491243 0,09568314 ! positive regulation of defense response GO:0031349 88 48 0,000 0,08663964 0,09758443 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,08663964 0,09753946 ! mitochondrial transport GO:0006839 94 48 0,000 0,08663964 0,09749454 ! cellular component disassembly GO:0022411 89 48 0,000 0,08663964 0,09744965 ! endosome transport GO:0016197 127 48 0,000 0,08663964 0,0974048 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,08663964 0,09736 ! male sex differentiation GO:0046661 93 48 0,000 0,08663964 0,09731524 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,08663964 0,09727051 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,08663964 0,09722583 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,08663964 0,09718119 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,08663964 0,09713659 ! methylation GO:0032259 97 48 0,000 0,08663964 0,09709204 ! response to calcium ion GO:0051592 94 49 0,000 0,08836364 0,09897862 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,08836364 0,09893326 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,08836364 0,09888794 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,08836364 0,09884266 ! regulation of action potential GO:0001508 102 50 0,000 0,09008444 0,10072141 ! regulation of ion transport GO:0043269 86 50 0,000 0,09008444 0,10067533 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,09008444 0,1006293 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,09008444 0,10058331 ! activation of caspase activity GO:0006919 95 50 0,000 0,09008444 0,10053736 ! regulation of ossification GO:0030278 123 50 0,000 0,09008444 0,10049145 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,09008444 0,10044558 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,09008444 0,10039976 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,09008444 0,10035398 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,09008444 0,10030824 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,09008444 0,10026254 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,09180203 0,10212767 ! viral infectious cycle GO:0019058 104 51 0,000 0,09180203 0,10208118 ! peptide metabolic process GO:0006518 80 51 0,000 0,09180203 0,10203474 ! response to temperature stimulus GO:0009266 84 51 0,000 0,09180203 0,10198834 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,09180203 0,10194198 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,09180203 0,10189567 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,09351643 0,10375143 ! Notch signaling pathway GO:0007219 111 52 0,000 0,09351643 0,10370433 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,09351643 0,10365728 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,09351643 0,10361027 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,09351643 0,1035633 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,09351643 0,10351638 ! excretion GO:0007588 87 52 0,000 0,09351643 0,1034695 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,09351643 0,10342266 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,09351643 0,10337586 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,09351643 0,1033291 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,09351643 0,10328239 ! amino acid activation GO:0043038 98 52 0,000 0,09351643 0,10323572 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,09522765 0,1050773 ! positive regulation of growth GO:0045927 96 53 0,000 0,09522765 0,10502986 ! inner ear development GO:0048839 89 53 0,000 0,09522765 0,10498246 ! chromatin remodeling GO:0006338 122 53 0,000 0,09522765 0,10493511 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,09522765 0,1048878 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,09522765 0,10484053 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,09522765 0,10479331 ! cartilage development GO:0051216 99 53 0,000 0,09522765 0,10474612 ! synapse organization GO:0050808 102 53 0,000 0,09522765 0,10469898 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,09693568 0,10652895 ! regulation of translational initiation GO:0006446 87 54 0,000 0,09693568 0,10648105 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,09693568 0,1064332 ! neuromuscular process GO:0050905 107 54 0,000 0,09693568 0,10638538 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,09693568 0,10633761 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,09693568 0,10628988 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,09693568 0,1062422 ! regulation of cell shape GO:0008360 142 54 0,000 0,09693568 0,10619456 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,09693568 0,10614696 ! RNA catabolic process GO:0006401 103 55 0,000 0,09864053 0,10796542 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,09864053 0,10791707 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,09864053 0,10786877 ! cell recognition GO:0008037 98 55 0,000 0,09864053 0,1078205 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,09864053 0,10777228 ! cell maturation GO:0048469 107 55 0,000 0,09864053 0,10772411 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,09864053 0,10767597 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,10034222 0,10948461 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,10034222 0,10943573 ! glucose catabolic process GO:0006007 88 56 0,000 0,10034222 0,1093869 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,10034222 0,10933811 ! regulation of DNA replication GO:0006275 105 56 0,000 0,10034222 0,10928936 ! RNA elongation GO:0006354 90 56 0,000 0,10034222 0,10924066 ! chloride transport GO:0006821 102 57 0,000 0,10204074 0,11104032 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,10204074 0,11099088 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,10204074 0,11094149 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,10204074 0,11089214 ! heart morphogenesis GO:0003007 105 57 0,000 0,10204074 0,11084283 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,10204074 0,11079357 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,10204074 0,11074435 ! regulation of actin filament length GO:0030832 118 58 0,000 0,1037361 0,11253432 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,1037361 0,11248437 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,1037361 0,11243447 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,1037361 0,11238461 ! aging GO:0007568 112 58 0,000 0,1037361 0,11233479 ! gastrulation GO:0007369 122 58 0,000 0,1037361 0,11228502 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,1037361 0,11223529 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,1037361 0,11218561 ! maintenance of location GO:0051235 124 58 0,000 0,1037361 0,11213597 ! nuclear export GO:0051168 110 59 0,000 0,10542831 0,1139148 ! establishment of organelle localization GO:0051656 122 59 0,000 0,10542831 0,11386444 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,10711737 0,11563753 ! DNA catabolic process GO:0006308 94 60 0,000 0,10711737 0,11558645 ! regulation of endocytosis GO:0030100 104 60 0,000 0,10711737 0,11553542 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,10711737 0,11548443 ! adult behavior GO:0030534 104 60 0,000 0,10711737 0,11543349 ! kidney development GO:0001822 133 60 0,000 0,10711737 0,1153826 ! positive regulation of secretion GO:0051047 110 61 0,000 0,10880329 0,11714695 ! regulation of cellular component size GO:0032535 125 61 0,000 0,10880329 0,11709534 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,10880329 0,11704378 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,10880329 0,11699227 ! regulation of heart contraction GO:0008016 123 61 0,000 0,10880329 0,11694079 ! camera-type eye development GO:0043010 126 61 0,000 0,10880329 0,11688937 ! proton transport GO:0015992 117 61 0,000 0,10880329 0,11683799 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,10880329 0,11678666 ! viral reproductive process GO:0022415 132 62 0,000 0,11048607 0,11854083 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,11048607 0,11848879 ! tRNA processing GO:0008033 102 62 0,000 0,11048607 0,1184368 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,11048607 0,11838485 ! regulation of mitosis GO:0007088 112 63 0,000 0,11216572 0,1201319 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,11216572 0,12007925 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,11216572 0,12002666 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,11216572 0,11997411 ! hydrogen transport GO:0006818 121 64 0,000 0,11384225 0,12171405 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,11384225 0,12166081 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,11551566 0,12339517 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,11551566 0,12334124 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,11551566 0,12328735 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,11551566 0,12323352 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,11551566 0,12317973 ! ear development GO:0043583 114 66 0,000 0,11718596 0,12490632 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,11718596 0,12485185 ! gonad development GO:0008406 115 66 0,000 0,11718596 0,12479742 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,11718596 0,12474305 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,11885314 0,12646264 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,11885314 0,12640759 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,11885314 0,12635258 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,11885314 0,12629762 ! secondary metabolic process GO:0019748 125 67 0,000 0,11885314 0,12624271 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,11885314 0,12618785 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,12051723 0,12789904 ! hexose catabolic process GO:0019320 113 68 0,000 0,12051723 0,12784351 ! extracellular matrix organization GO:0030198 146 68 0,000 0,12051723 0,12778802 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,12051723 0,12773258 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,12051723 0,12767719 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,12051723 0,12762185 ! viral reproduction GO:0016032 142 68 0,000 0,12051723 0,12756655 ! adaptive immune response GO:0002250 126 68 0,000 0,12051723 0,1275113 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,12051723 0,1274561 ! cell projection assembly GO:0030031 138 68 0,000 0,12051723 0,12740095 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,12217822 0,12910095 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,12217822 0,12904514 ! urogenital system development GO:0001655 149 69 0,000 0,12217822 0,12898937 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,12217822 0,12893365 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,12217822 0,12887798 ! developmental maturation GO:0021700 128 69 0,000 0,12217822 0,12882236 ! single fertilization GO:0007338 83 69 0,000 0,12217822 0,12876678 ! cell redox homeostasis GO:0045454 114 70 0,000 0,12383613 0,13045781 ! germ cell development GO:0007281 133 70 0,000 0,12383613 0,13040158 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,12383613 0,13034539 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,12549094 0,13203031 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,12549094 0,13197347 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,12549094 0,13191668 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,12549094 0,13185995 ! appendage morphogenesis GO:0035107 150 72 0,000 0,12714268 0,13353808 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,12714268 0,13348069 ! B cell activation GO:0042113 179 72 0,000 0,12714268 0,13342335 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,12714268 0,13336607 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,12714268 0,13330883 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,12714268 0,13325164 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,12714268 0,1331945 ! appendage development GO:0048736 151 73 0,000 0,12879135 0,13486381 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,12879135 0,13480602 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,12879135 0,13474829 ! regulation of immune effector process GO:0002697 156 73 0,000 0,12879135 0,13469061 ! acute inflammatory response GO:0002526 118 74 0,000 0,13043694 0,13635321 ! amino acid transport GO:0006865 148 74 0,000 0,13043694 0,13629489 ! regulation of caspase activity GO:0043281 136 74 0,000 0,13043694 0,13623662 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,13043694 0,1361784 ! organelle localization GO:0051640 155 74 0,000 0,13043694 0,13612023 ! transition metal ion transport GO:0000041 143 75 0,000 0,13207948 0,13777548 ! reproductive structure development GO:0048608 131 75 0,000 0,13207948 0,13771667 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,13207948 0,13765792 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,13207948 0,13759922 ! eye development GO:0001654 155 75 0,000 0,13207948 0,13754056 ! rhythmic process GO:0048511 142 75 0,000 0,13207948 0,13748196 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,13371896 0,13912922 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,13371896 0,13906999 ! regulation of blood pressure GO:0008217 134 76 0,000 0,13371896 0,13901081 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,13371896 0,13895169 ! amine catabolic process GO:0009310 136 77 0,000 0,13535538 0,14059235 ! neurotransmitter transport GO:0006836 142 77 0,000 0,13535538 0,1405326 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,13535538 0,1404729 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,13535538 0,14041325 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,13535538 0,14035365 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,13535538 0,14029411 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,13535538 0,14023461 ! regulation of catabolic process GO:0009894 173 77 0,000 0,13535538 0,14017516 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,13698877 0,14180659 ! antigen processing and presentation GO:0019882 117 78 0,000 0,13698877 0,14174653 ! fertilization GO:0009566 99 78 0,000 0,13698877 0,14168652 ! blood coagulation GO:0007596 151 79 0,000 0,13861911 0,1433121 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,13861911 0,14325148 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,13861911 0,1431909 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,13861911 0,14313038 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,13861911 0,14306991 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,13861911 0,1430095 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,14024642 0,14462727 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,14024642 0,14456625 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,14024642 0,14450527 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,14024642 0,14444435 ! muscle cell differentiation GO:0042692 178 81 0,000 0,1418707 0,14605568 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,1418707 0,14599415 ! protein import into nucleus GO:0006606 174 82 0,000 0,14349196 0,14760036 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,1451102 0,14920211 ! exocytosis GO:0006887 153 83 0,000 0,1451102 0,14913934 ! response to drug GO:0042493 149 83 0,000 0,1451102 0,14907663 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,1451102 0,14901396 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,1451102 0,14895135 ! nuclear import GO:0051170 177 83 0,000 0,1451102 0,14888879 ! inorganic anion transport GO:0015698 156 83 0,000 0,1451102 0,14882629 ! response to metal ion GO:0010038 158 84 0,000 0,14672543 0,15041973 ! T cell activation GO:0042110 189 84 0,000 0,14672543 0,15035664 ! response to nutrient GO:0007584 135 84 0,000 0,14672543 0,15029359 ! digestion GO:0007586 130 84 0,000 0,14672543 0,1502306 ! regulation of ligase activity GO:0051340 147 84 0,000 0,14672543 0,15016767 ! hemostasis GO:0007599 165 85 0,000 0,14833765 0,15175414 ! negative regulation of transport GO:0051051 164 85 0,000 0,14833765 0,15169061 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,14833765 0,15162715 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,14833765 0,15156373 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,14833765 0,15150037 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,14833765 0,15143706 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,14994687 0,15301596 ! regulation of lyase activity GO:0051339 169 86 0,000 0,14994687 0,15295207 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,1515531 0,15452597 ! mitochondrion organization GO:0007005 159 87 0,000 0,1515531 0,1544615 ! alcohol catabolic process GO:0046164 142 87 0,000 0,1515531 0,15439709 ! nucleosome assembly GO:0006334 126 87 0,000 0,1515531 0,15433273 ! regulation of protein transport GO:0051223 165 87 0,000 0,1515531 0,15426842 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,15315633 0,15583545 ! amine biosynthetic process GO:0009309 146 88 0,000 0,15315633 0,15577058 ! sensory perception of smell GO:0007608 117 88 0,000 0,15315633 0,15570575 ! chromatin assembly GO:0031497 128 88 0,000 0,15315633 0,15564098 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,15315633 0,15557627 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,15475658 0,15713647 ! tube morphogenesis GO:0035239 194 89 0,000 0,15475658 0,15707118 ! cellular defense response GO:0006968 123 89 0,000 0,15475658 0,15700595 ! protein localization in nucleus GO:0034504 192 89 0,000 0,15475658 0,15694078 ! regulation of neurological system process GO:0031644 175 89 0,000 0,15475658 0,15687566 ! response to inorganic substance GO:0010035 173 90 0,000 0,15635386 0,15842906 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,15635386 0,15836338 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,15635386 0,15829775 ! response to unfolded protein GO:0006986 139 90 0,000 0,15635386 0,15823218 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,15635386 0,15816666 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,15794816 0,15971331 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,15794816 0,15964723 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,15953949 0,16118899 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,15953949 0,16112235 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,16112786 0,16265924 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,16112786 0,16259205 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,16112786 0,16252492 ! vitamin metabolic process GO:0006766 153 93 0,000 0,16112786 0,16245784 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,16271327 0,16398866 ! female pregnancy GO:0007565 166 94 0,000 0,16271327 0,16392104 ! sterol metabolic process GO:0016125 166 94 0,000 0,16271327 0,16385347 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,16271327 0,16378596 ! regulation of defense response GO:0031347 171 95 0,000 0,16429573 0,16531074 ! nucleosome organization GO:0034728 143 95 0,000 0,16429573 0,16524268 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,16429573 0,16517468 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,16429573 0,16510673 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,16429573 0,16503884 ! sex differentiation GO:0007548 171 96 0,000 0,16587524 0,16655702 ! response to protein stimulus GO:0051789 158 96 0,000 0,16587524 0,16648859 ! regulation of T cell activation GO:0050863 175 96 0,000 0,16587524 0,16642021 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,16745182 0,167933 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,16745182 0,16786409 ! transcription initiation GO:0006352 171 97 0,000 0,16745182 0,16779524 ! regulation of protein localization GO:0032880 188 97 0,000 0,16745182 0,16772644 ! leukocyte differentiation GO:0002521 232 98 0,000 0,16902545 0,16923327 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,16902545 0,16916394 ! mRNA transport GO:0051028 185 100 0,000 0,17216394 0,17223444 ! hormone metabolic process GO:0042445 171 100 0,000 0,17216394 0,17216394