pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1324-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of vasoconstriction GO:0045907 9 5 2,000 1,285E-07 2,956E-04 ! positive regulation of microtubule polymerization GO:0031116 9 5 2,000 1,285E-07 1,478E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 3,000 1,356E-07 1,039E-04 ! gas homeostasis GO:0033483 11 6 2,000 2,566E-07 1,475E-04 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 2,000 2,566E-07 1,18E-04 ! regulation of microtubule polymerization GO:0031113 11 6 2,000 2,566E-07 9,836E-05 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 2,000 4,483E-07 1,473E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 7,161E-07 2,059E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 7,161E-07 1,83E-04 ! mammary gland development GO:0030879 57 31 3,000 8,637E-07 1,987E-04 ! regulation of epithelial cell differentiation GO:0030856 13 9 2,000 1,072E-06 2,242E-04 ! positive regulation of protein polymerization GO:0032273 15 9 2,000 1,072E-06 2,055E-04 ! gland development GO:0048732 148 77 4,000 1,088E-06 1,926E-04 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 1,529E-06 2,512E-04 ! gland morphogenesis GO:0022612 23 12 2,000 2,794E-06 4,285E-04 ! positive regulation of protein complex assembly GO:0031334 19 13 2,000 3,627E-06 5,213E-04 ! lipid localization GO:0010876 24 13 2,000 3,627E-06 4,906E-04 GO:0019915|lipid storage, ! calcium ion transport GO:0006816 167 99 4,000 3,79E-06 4,842E-04 ! divalent metal ion transport GO:0070838 171 100 4,000 3,982E-06 4,82E-04 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 2,000 4,608E-06 5,299E-04 ! regulation of vasodilation GO:0042312 24 15 2,000 5,75E-06 6,298E-04 ! inactivation of MAPK activity GO:0000188 27 17 2,000 8,565E-06 8,954E-04 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 9,653E-06 9,653E-04 ! positive regulation of cytoskeleton organization GO:0051495 33 18 2,000 1,026E-05 9,833E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,036E-05 9,534E-04 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,111E-05 9,83E-04 ! regulation of fatty acid metabolic process GO:0019217 28 19 2,000 1,216E-05 1,036E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 2,000 1,216E-05 9,992E-04 ! negative regulation of transferase activity GO:0051348 105 61 3,000 1,36E-05 1,078E-03 ! regulation of vasoconstriction GO:0019229 31 21 2,000 1,664E-05 1,276E-03 ! regulation of MAPKKK cascade GO:0043408 101 65 3,000 1,752E-05 1,3E-03 ! vasculogenesis GO:0001570 33 22 2,000 1,924E-05 1,383E-03 ! regulation of smooth muscle contraction GO:0006940 36 22 2,000 1,924E-05 1,341E-03 ! membrane depolarization GO:0051899 35 22 2,000 1,924E-05 1,301E-03 ! regulation of blood coagulation GO:0030193 34 22 2,000 1,924E-05 1,264E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 2,52E-05 1,61E-03 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 2,52E-05 1,566E-03 ! regulation of oxidoreductase activity GO:0051341 39 24 2,000 2,52E-05 1,525E-03 ! response to hypoxia GO:0001666 132 72 3,000 2,63E-05 1,551E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 2,858E-05 1,644E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 2,000 2,858E-05 1,604E-03 ! response to oxygen levels GO:0070482 137 74 3,000 2,931E-05 1,605E-03 ! negative regulation of protein kinase cascade GO:0010741 51 26 2,000 3,226E-05 1,725E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 2,000 3,226E-05 1,686E-03 ! regulation of coagulation GO:0050818 39 26 2,000 3,226E-05 1,649E-03 ! cholesterol homeostasis GO:0042632 46 28 2,000 4,051E-05 2,026E-03 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 2,000 4,051E-05 1,982E-03 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 4,051E-05 1,941E-03 ! cholesterol transport GO:0030301 46 30 2,000 5,004E-05 2,349E-03 GO:0015918|sterol transport, ! regulation of microtubule-based process GO:0032886 58 30 2,000 5,004E-05 2,302E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 5,298E-05 2,389E-03 ! skeletal muscle tissue development GO:0007519 123 87 3,000 5,543E-05 2,452E-03 GO:0060538|skeletal muscle organ development, ! parathyroid gland development GO:0060017 8 5 1,000 5,609E-05 2,434E-03 ! interphase GO:0051325 159 88 3,000 5,797E-05 2,469E-03 ! neutral lipid metabolic process GO:0006638 41 32 2,000 6,093E-05 2,548E-03 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 55 33 2,000 6,691E-05 2,748E-03 ! glycerol ether metabolic process GO:0006662 44 34 2,000 7,326E-05 2,956E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 7,326E-05 2,905E-03 ! protein homooligomerization GO:0051260 52 35 2,000 7,999E-05 3,118E-03 ! male meiosis GO:0007140 7 6 1,000 8,401E-05 3,22E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 8,401E-05 3,167E-03 ! organic ether metabolic process GO:0018904 46 36 2,000 8,712E-05 3,232E-03 ! tissue remodeling GO:0048771 62 36 2,000 8,712E-05 3,181E-03 ! JNK cascade GO:0007254 54 39 2,000 1,11E-04 3,987E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,174E-04 4,155E-03 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,174E-04 4,092E-03 ! vesicle fusion GO:0006906 15 7 1,000 1,174E-04 4,031E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 1,174E-04 3,972E-03 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 2,000 1,197E-04 3,992E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 1,197E-04 3,935E-03 ! positive regulation of DNA binding GO:0043388 57 41 2,000 1,29E-04 4,178E-03 ! regulation of JAK-STAT cascade GO:0046425 61 42 2,000 1,387E-04 4,43E-03 ! positive regulation of binding GO:0051099 59 43 2,000 1,488E-04 4,689E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,488E-04 4,626E-03 ! vesicle organization GO:0016050 79 43 2,000 1,488E-04 4,564E-03 ! response to insulin stimulus GO:0032868 63 43 2,000 1,488E-04 4,504E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,563E-04 4,67E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,563E-04 4,61E-03 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 1,563E-04 4,552E-03 ! S phase GO:0051320 8 8 1,000 1,563E-04 4,495E-03 GO:0000084|S phase of mitotic cell cycle, ! response to UV GO:0009411 75 46 2,000 1,822E-04 5,172E-03 ! regulation of protein polymerization GO:0032271 71 47 2,000 1,942E-04 5,448E-03 ! thymus development GO:0048538 15 9 1,000 2,007E-04 5,561E-03 ! localization within membrane GO:0051668 15 9 1,000 2,007E-04 5,495E-03 ! regulation of muscle contraction GO:0006937 69 48 2,000 2,069E-04 5,597E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 2,478E-04 6,628E-03 ! positive regulation of cell migration GO:0030335 92 51 2,000 2,478E-04 6,551E-03 ! positive regulation of organelle organization GO:0010638 82 51 2,000 2,478E-04 6,477E-03 ! hippocampus development GO:0021766 19 10 1,000 2,505E-04 6,473E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 2,505E-04 6,401E-03 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 2,505E-04 6,331E-03 ! T cell receptor signaling pathway GO:0050852 18 10 1,000 2,505E-04 6,262E-03 ! regulation of protein complex assembly GO:0043254 81 54 2,000 2,937E-04 7,263E-03 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 3,057E-04 7,48E-03 ! positive regulation of cell motion GO:0051272 99 56 2,000 3,271E-04 7,92E-03 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 3,447E-04 8,259E-03 ! histone acetylation GO:0016573 23 12 1,000 3,663E-04 8,685E-03 ! peptidyl-lysine modification GO:0018205 18 12 1,000 3,663E-04 8,596E-03 ! cell-matrix adhesion GO:0007160 114 61 2,000 4,212E-04 9,785E-03 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 4,322E-04 9,941E-03 ! organelle fusion GO:0048284 28 13 1,000 4,322E-04 9,842E-03 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 4,322E-04 9,746E-03 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 5,035E-04 0,01124237 ! limbic system development GO:0021761 25 14 1,000 5,035E-04 0,01113427 ! protein oligomerization GO:0051259 100 65 2,000 5,078E-04 0,01112272 ! cell-substrate adhesion GO:0031589 121 66 2,000 5,311E-04 0,01152321 ! lipid phosphorylation GO:0046834 23 15 1,000 5,8E-04 0,01246801 ! cerebral cortex development GO:0021987 29 15 1,000 5,8E-04 0,01235257 ! DNA integration GO:0015074 22 15 1,000 5,8E-04 0,01223924 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 5,8E-04 0,01212798 ! protein amino acid acetylation GO:0006473 28 16 1,000 6,619E-04 0,01371476 ! regulation of dephosphorylation GO:0035303 33 16 1,000 6,619E-04 0,01359231 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 1,000 6,619E-04 0,01347202 ! regulation of peptidase activity GO:0052547 106 72 2,000 6,853E-04 0,01382552 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 7,423E-04 0,014847 ! signal complex assembly GO:0007172 29 17 1,000 7,49E-04 0,01485078 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 7,49E-04 0,01472385 ! actin filament bundle formation GO:0051017 26 17 1,000 7,49E-04 0,01459907 ! regulation of DNA binding GO:0051101 119 77 2,000 8,335E-04 0,01611004 ! somitogenesis GO:0001756 24 18 1,000 8,413E-04 0,01612564 ! activation of JUN kinase activity GO:0007257 23 18 1,000 8,413E-04 0,01599237 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 9,389E-04 0,01770034 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 9,389E-04 0,01755643 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 9,389E-04 0,01741485 ! pallium development GO:0021543 38 20 1,000 1,042E-03 0,01916582 ! positive regulation of B cell activation GO:0050871 31 20 1,000 1,042E-03 0,01901371 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 1,111E-03 0,02011234 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 1,111E-03 0,01995521 ! regulation of membrane potential GO:0042391 128 85 2,000 1,111E-03 0,01980052 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 1,111E-03 0,01964821 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 1,15E-03 0,0201823 ! protein amino acid acylation GO:0043543 37 21 1,000 1,15E-03 0,0200294 ! vesicle docking GO:0048278 27 21 1,000 1,15E-03 0,0198788 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 1,15E-03 0,01973045 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 1,263E-03 0,02150996 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 1,000 1,263E-03 0,0213518 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! positive regulation of JUN kinase activity GO:0043507 28 22 1,000 1,263E-03 0,02119595 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 1,381E-03 0,02301133 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 1,381E-03 0,02284579 ! cellular response to oxidative stress GO:0034599 33 23 1,000 1,381E-03 0,0226826 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 1,381E-03 0,02252173 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 1,44E-03 0,02332002 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 1,44E-03 0,02315695 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 1,504E-03 0,02402072 ! regulation of binding GO:0051098 151 95 2,000 1,531E-03 0,02427873 ! regulation of response to external stimulus GO:0032101 139 96 2,000 1,577E-03 0,02484887 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 1,577E-03 0,02467983 ! response to light stimulus GO:0009416 153 96 2,000 1,577E-03 0,02451307 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 1,632E-03 0,02519495 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,766E-03 0,02707135 ! negative regulation of protein modification process GO:0031400 50 26 1,000 1,766E-03 0,02689207 ! membrane docking GO:0022406 39 27 1,000 1,904E-03 0,0288085 ! respiratory gaseous exchange GO:0007585 47 27 1,000 1,904E-03 0,02862021 ! immune response-activating signal transduction GO:0002757 38 28 1,000 2,047E-03 0,03057508 GO:0002764|immune response-regulating signal transduction, ! regulation of B cell activation GO:0050864 42 28 1,000 2,047E-03 0,03037782 ! mismatch repair GO:0006298 34 29 1,000 2,196E-03 0,03236961 ! telencephalon development GO:0021537 52 29 1,000 2,196E-03 0,03216344 ! segmentation GO:0035282 41 31 1,000 2,507E-03 0,03649314 ! calcium-mediated signaling GO:0019722 50 32 1,000 2,67E-03 0,03862245 ! feeding behavior GO:0007631 45 34 1,000 3,011E-03 0,04327909 ! neuron migration GO:0001764 46 34 1,000 3,011E-03 0,04301027 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 3,188E-03 0,04526654 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 3,371E-03 0,04756292 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 1,000 3,371E-03 0,0472729 ! learning GO:0007612 67 37 1,000 3,558E-03 0,04959595 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 3,947E-03 0,05468233 ! regulation of JNK cascade GO:0046328 58 41 1,000 4,354E-03 0,05996745 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 4,565E-03 0,0624961 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 5E-03 0,06805272 ! positive regulation of cell cycle GO:0045787 77 45 1,000 5,225E-03 0,0706917 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 5,225E-03 0,0702783 ! histone modification GO:0016570 68 46 1,000 5,454E-03 0,07293489 ! endocrine system development GO:0035270 83 47 1,000 5,688E-03 0,07562133 ! covalent chromatin modification GO:0016569 75 47 1,000 5,688E-03 0,07518673 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 5,688E-03 0,07475709 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 6,169E-03 0,08061992 ! membrane fusion GO:0006944 80 50 1,000 6,416E-03 0,08337814 ! lipid modification GO:0030258 73 50 1,000 6,416E-03 0,08290972 ! activation of phospholipase C activity GO:0007202 87 51 1,000 6,668E-03 0,08568174 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 6,925E-03 0,08847977 ! regulation of phospholipase activity GO:0010517 90 54 1,000 7,45E-03 0,09467122 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 7,45E-03 0,09415105 ! positive regulation of lipase activity GO:0060193 90 54 1,000 7,45E-03 0,09363657 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 7,993E-03 0,09991811 ! activation of MAPK activity GO:0000187 84 59 1,000 8,841E-03 0,10991247 ! lung development GO:0030324 94 59 1,000 8,841E-03 0,10932154 ! actin filament organization GO:0007015 95 59 1,000 8,841E-03 0,10873694 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 9,132E-03 0,11171893 ! regulation of cellular response to stress GO:0080135 85 61 1,000 9,427E-03 0,11472112 ! meiosis GO:0007126 96 61 1,000 9,427E-03 0,11411733 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cell growth GO:0030308 106 62 1,000 9,727E-03 0,11712649 ! respiratory tube development GO:0030323 99 62 1,000 9,727E-03 0,11651645 ! meiotic cell cycle GO:0051321 97 62 1,000 9,727E-03 0,11591274 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,01003031 0,11891604 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,01003031 0,11830621 ! regulation of lipase activity GO:0060191 109 63 1,000 0,01003031 0,11770261 ! negative regulation of cell size GO:0045792 108 64 1,000 0,01033822 0,1207 ! respiratory system development GO:0060541 100 64 1,000 0,01033822 0,12009041 ! activation of immune response GO:0002253 83 65 1,000 0,0106503 0,12309387 ! axon guidance GO:0007411 99 66 1,000 0,01096652 0,12611499 ! learning or memory GO:0007611 123 68 1,000 0,01161133 0,13286602 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01195614 0,13613423 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01195614 0,13546362 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01195614 0,13479958 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01195614 0,13414202 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01195614 0,13349085 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01195614 0,13284596 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01195614 0,13220728 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01195614 0,13157471 ! sleep GO:0030431 11 5 0,000 0,01195614 0,13094816 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01195614 0,13032756 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01195614 0,1297128 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01195614 0,12910382 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01195614 0,12850053 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01195614 0,12790286 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01195614 0,12731072 ! tongue development GO:0043586 6 5 0,000 0,01195614 0,12672403 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01195614 0,12614273 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01195614 0,12556673 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01195614 0,12499597 ! cobalt ion transport GO:0006824 9 5 0,000 0,01195614 0,12443038 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01195614 0,12386988 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01195614 0,12331441 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01195614 0,1227639 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01195614 0,12221829 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01195614 0,1216775 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01195614 0,12114147 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01195614 0,12061015 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01195614 0,12008347 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01195614 0,11956137 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01195614 0,11904379 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01195614 0,11853067 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01195614 0,11802195 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01195614 0,11751758 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01195614 0,11701751 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01195614 0,11652167 ! malate metabolic process GO:0006108 7 5 0,000 0,01195614 0,11603002 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01195614 0,1155425 ! behavioral response to pain GO:0048266 7 5 0,000 0,01195614 0,11505906 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01195614 0,11457964 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01195614 0,11410421 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01195614 0,1136327 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01195614 0,11316508 ! mating behavior GO:0007617 6 5 0,000 0,01195614 0,11270129 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01195614 0,11224128 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01195614 0,11178502 ! rhythmic behavior GO:0007622 12 5 0,000 0,01195614 0,11133245 ! copulation GO:0007620 7 5 0,000 0,01195614 0,11088353 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01195614 0,11043821 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01195614 0,10999646 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01195614 0,10955822 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01195614 0,10912347 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01195614 0,10869215 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01195614 0,10826423 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01195614 0,10783966 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01195614 0,10741842 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01195614 0,10700045 ! response to protozoan GO:0001562 9 5 0,000 0,01195614 0,10658571 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01195614 0,10617419 ! lymph vessel development GO:0001945 7 5 0,000 0,01195614 0,10576582 ! endochondral ossification GO:0001958 12 5 0,000 0,01195614 0,10536059 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01195614 0,10495845 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01195614 0,10455937 ! anagen GO:0042640 6 5 0,000 0,01195614 0,10416331 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01195614 0,10377024 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01195614 0,10338013 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01195614 0,10299294 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01195614 0,10260864 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01195614 0,10222719 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01195614 0,10184857 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01195614 0,10147275 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01195614 0,10109969 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01195614 0,10072936 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01195614 0,10036173 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01195614 0,09999678 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01195614 0,09963447 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01195614 0,09927478 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01195614 0,09891768 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01195614 0,09856313 ! ovulation GO:0030728 6 5 0,000 0,01195614 0,09821112 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01195614 0,09786162 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01195614 0,09751459 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01195614 0,09717002 ! response to pH GO:0009268 9 5 0,000 0,01195614 0,09682787 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01195614 0,09648812 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01195614 0,09615075 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01195614 0,09581573 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01195614 0,09548304 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01195614 0,09515265 ! polyol catabolic process GO:0046174 7 5 0,000 0,01195614 0,09482453 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01195614 0,09449868 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01195614 0,09417505 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01195614 0,09385363 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01195614 0,0935344 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01195614 0,09321734 ! urea metabolic process GO:0019627 6 5 0,000 0,01195614 0,09290241 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01195614 0,09258961 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01195614 0,09227891 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01195614 0,09197028 ! neutrophil activation GO:0042119 5 5 0,000 0,01195614 0,09166371 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01195614 0,09135918 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01195614 0,09105667 ! response to food GO:0032094 5 5 0,000 0,01195614 0,09075615 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01195614 0,09045761 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01195614 0,09016103 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01195614 0,08986639 ! forebrain neuron development GO:0021884 7 5 0,000 0,01195614 0,08957366 ! melanosome organization GO:0032438 7 5 0,000 0,01195614 0,08928284 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01195614 0,0889939 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01195614 0,08870682 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01195614 0,08842159 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01195614 0,08813819 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01195614 0,0878566 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01195614 0,0875768 ! nucleoside transport GO:0015858 6 5 0,000 0,01195614 0,08729878 ! nucleoside salvage GO:0043174 7 5 0,000 0,01195614 0,08702251 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01195614 0,086748 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01195614 0,0864752 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01195614 0,08620412 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01195614 0,08593473 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01195614 0,08566702 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01195614 0,08540098 ! depyrimidination GO:0045008 8 5 0,000 0,01195614 0,08513658 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01195614 0,08487381 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01195614 0,08461266 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01195614 0,08435311 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01195614 0,08409515 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01195614 0,08383876 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01195614 0,08358393 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01195614 0,08333065 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01195614 0,0830789 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01195614 0,08282866 ! monocyte differentiation GO:0030224 8 5 0,000 0,01195614 0,08257992 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01195614 0,08233268 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01195614 0,08208691 ! centrosome duplication GO:0051298 5 5 0,000 0,01195614 0,0818426 ! response to UV-C GO:0010225 6 5 0,000 0,01195614 0,08159975 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01195614 0,08135833 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01195614 0,08111833 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01195614 0,08087975 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01195614 0,08064256 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01195614 0,08040677 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01195614 0,08017235 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01195614 0,07993929 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01195614 0,07970758 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01195614 0,07947721 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01195614 0,07924817 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01195614 0,07902044 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01195614 0,07879402 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01195614 0,0785689 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01195614 0,07834506 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01195614 0,07812248 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01195614 0,07790117 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01195614 0,07768111 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01195614 0,07746229 ! neural tube patterning GO:0021532 6 5 0,000 0,01195614 0,0772447 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01195614 0,07702833 ! histone demethylation GO:0016577 9 5 0,000 0,01195614 0,07681317 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01195614 0,0765992 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01195614 0,07638643 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01195614 0,07617483 ! enteric nervous system development GO:0048484 8 5 0,000 0,01195614 0,0759644 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01195614 0,07575514 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01195614 0,07554702 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01195614 0,07534004 ! transcription termination GO:0006353 8 5 0,000 0,01195614 0,07513419 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01195614 0,07492947 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01195614 0,07472585 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01195614 0,07452335 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01195614 0,07432193 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01195614 0,0741216 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01195614 0,07392235 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01195614 0,07372417 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01195614 0,07352704 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01195614 0,07333097 ! apical protein localization GO:0045176 6 5 0,000 0,01195614 0,07313594 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01195614 0,07294195 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01195614 0,07274898 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01195614 0,07255703 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01195614 0,07236609 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01195614 0,07217615 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01195614 0,07198721 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01195614 0,07179925 ! glial cell migration GO:0008347 10 5 0,000 0,01195614 0,07161228 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01195614 0,07142627 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01195614 0,07124123 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01195614 0,07105714 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01195614 0,07087401 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01195614 0,07069181 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01195614 0,07051055 ! neural plate development GO:0001840 6 5 0,000 0,01195614 0,07033022 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01195614 0,0701508 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01195614 0,0699723 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01195614 0,06979471 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01195614 0,06961801 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01195614 0,06944221 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01195614 0,06926729 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01195614 0,06909325 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01195614 0,06892009 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01195614 0,06874779 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01195614 0,06857635 ! spindle assembly GO:0051225 5 5 0,000 0,01195614 0,06840576 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01195614 0,06823602 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01195614 0,06806711 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01195614 0,06789905 ! organ regeneration GO:0031100 7 5 0,000 0,01195614 0,06773181 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01195614 0,06756539 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01195614 0,06739979 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01195614 0,067235 GO:0055081|anion homeostasis, ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,01227249 0,0688457 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,01294983 0,07246865 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,01364319 0,07616345 ! negative regulation of growth GO:0045926 123 75 1,000 0,01399583 0,07794287 ! tRNA transcription GO:0009304 11 6 0,000 0,01433056 0,07961424 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01433056 0,0794224 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01433056 0,07923148 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01433056 0,07904147 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01433056 0,07885238 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01433056 0,07866419 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01433056 0,07847689 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01433056 0,07829048 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01433056 0,07810496 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01433056 0,07792032 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01433056 0,07773654 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01433056 0,07755363 ! prostate gland development GO:0030850 9 6 0,000 0,01433056 0,07737158 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01433056 0,07719038 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01433056 0,07701003 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01433056 0,07683052 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01433056 0,07665185 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01433056 0,076474 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01433056 0,07629698 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01433056 0,07612077 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01433056 0,07594538 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01433056 0,07577079 ! neuron adhesion GO:0007158 9 6 0,000 0,01433056 0,075597 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01433056 0,07542401 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01433056 0,07525181 ! signal peptide processing GO:0006465 8 6 0,000 0,01433056 0,0750804 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01433056 0,07490976 ! mRNA stabilization GO:0048255 15 6 0,000 0,01433056 0,0747399 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01433056 0,0745708 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01433056 0,07440247 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01433056 0,0742349 ! opsonization GO:0008228 8 6 0,000 0,01433056 0,07406808 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01433056 0,073902 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01433056 0,07373668 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01433056 0,07357209 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01433056 0,07340823 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01433056 0,0732451 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01433056 0,07308269 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01433056 0,072921 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01433056 0,07276003 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01433056 0,07259977 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01433056 0,07244021 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01433056 0,07228135 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01433056 0,07212318 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01433056 0,07196571 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01433056 0,07180892 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01433056 0,07165281 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01433056 0,07149738 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01433056 0,07134263 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01433056 0,07118854 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01433056 0,07103512 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01433056 0,07088235 ! thymic T cell selection GO:0045061 12 6 0,000 0,01433056 0,07073024 ! protein lipoylation GO:0009249 10 6 0,000 0,01433056 0,07057879 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01433056 0,07042798 ! pigment granule organization GO:0048753 11 6 0,000 0,01433056 0,07027781 ! drug transport GO:0015893 6 6 0,000 0,01433056 0,07012829 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01433056 0,06997939 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01433056 0,06983113 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01433056 0,0696835 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01433056 0,06953649 ! histidine metabolic process GO:0006547 6 6 0,000 0,01433056 0,06939009 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01433056 0,06924432 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01433056 0,06909915 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01433056 0,06895459 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01433056 0,06881063 ! adenohypophysis development GO:0021984 10 6 0,000 0,01433056 0,06866728 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01433056 0,06852452 ! hyperosmotic response GO:0006972 8 6 0,000 0,01433056 0,06838235 ! microtubule nucleation GO:0007020 10 6 0,000 0,01433056 0,06824077 ! ER overload response GO:0006983 7 6 0,000 0,01433056 0,06809978 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01433056 0,06795937 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01433056 0,06781954 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01433056 0,06768028 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01433056 0,06754159 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01433056 0,06740346 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01433056 0,06726591 ! response to dietary excess GO:0002021 7 6 0,000 0,01433056 0,06712891 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01433056 0,06699247 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01433056 0,06685658 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01433056 0,06672124 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01433056 0,06658645 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01433056 0,06645221 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01433056 0,0663185 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01433056 0,06618533 ! neuron apoptosis GO:0051402 8 6 0,000 0,01433056 0,06605269 ! organic alcohol transport GO:0015850 9 6 0,000 0,01433056 0,06592059 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01433056 0,06578901 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01433056 0,06565796 ! male sex determination GO:0030238 9 6 0,000 0,01433056 0,06552742 ! carnitine transport GO:0015879 8 6 0,000 0,01433056 0,06539741 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01433056 0,06526791 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01433056 0,06513892 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01433056 0,06501044 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01433056 0,06488247 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01433056 0,064755 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01433056 0,06462803 ! parturition GO:0007567 12 6 0,000 0,01433056 0,06450155 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01433056 0,06437557 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01433056 0,06425009 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01433056 0,06412509 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01433056 0,06400057 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01433056 0,06387654 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01433056 0,06375299 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01433056 0,06362991 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01433056 0,06350731 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01433056 0,06338518 ! macrophage differentiation GO:0030225 10 6 0,000 0,01433056 0,06326352 ! astrocyte development GO:0014002 14 6 0,000 0,01433056 0,06314233 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01433056 0,06302159 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01433056 0,06290132 ! interaction with symbiont GO:0051702 8 6 0,000 0,01433056 0,06278151 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01433056 0,06266216 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01433056 0,06254325 ! eating behavior GO:0042755 6 6 0,000 0,01433056 0,0624248 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01433056 0,06230679 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01433056 0,06218923 ! response to copper ion GO:0046688 9 6 0,000 0,01433056 0,06207212 ! DNA topological change GO:0006265 8 6 0,000 0,01433056 0,06195544 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01433056 0,0618392 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01433056 0,0617234 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01433056 0,06160803 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01433056 0,06149309 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01433056 0,06137857 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01433056 0,06126449 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01433056 0,06115082 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01433056 0,06103758 ! hair follicle maturation GO:0048820 7 6 0,000 0,01433056 0,06092476 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01433056 0,06081235 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01433056 0,06070036 ! Schwann cell development GO:0014044 14 6 0,000 0,01433056 0,06058878 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01433056 0,0604776 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01433056 0,06036684 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01433056 0,06025648 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01433056 0,06014652 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01433056 0,06003697 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01433056 0,05992781 ! histone ubiquitination GO:0016574 7 6 0,000 0,01433056 0,05981905 ! regulation of meiosis GO:0040020 10 6 0,000 0,01433056 0,05971068 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01433056 0,0596027 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01433056 0,05949512 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01433056 0,05938792 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01433056 0,0592811 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01433056 0,05917468 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01433056 0,05906863 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01433056 0,05896296 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01433056 0,05885767 ! receptor internalization GO:0031623 9 6 0,000 0,01433056 0,05875275 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01433056 0,05864821 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01433056 0,05854404 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01433056 0,05844024 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01433056 0,0583368 ! protein deubiquitination GO:0016579 8 6 0,000 0,01433056 0,05823374 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01433056 0,05813103 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01433056 0,05802869 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01433056 0,0579267 ! axonal fasciculation GO:0007413 9 6 0,000 0,01433056 0,05782508 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01433056 0,05772381 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01433056 0,05762289 ! midbrain development GO:0030901 6 6 0,000 0,01433056 0,05752233 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01433056 0,05742212 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01433056 0,05732225 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01433056 0,05722273 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01433056 0,05712356 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01433056 0,05702473 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01433056 0,05692624 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01433056 0,05682809 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01433056 0,05673028 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01433056 0,05663281 ! adult feeding behavior GO:0008343 6 6 0,000 0,01433056 0,05653567 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01433056 0,05643886 ! blastocyst growth GO:0001832 15 6 0,000 0,01433056 0,05634238 ! pigment granule transport GO:0051904 12 6 0,000 0,01433056 0,05624624 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01433056 0,05615042 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01433056 0,05605492 ! catecholamine transport GO:0051937 7 6 0,000 0,01433056 0,05595975 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01433056 0,05586491 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01433056 0,05577038 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01433056 0,05567617 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01433056 0,05558228 ! protein prenylation GO:0018342 10 6 0,000 0,01433056 0,05548871 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01433056 0,05539545 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01433056 0,05530251 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01433056 0,05520987 ! ATP biosynthetic process GO:0006754 118 79 1,000 0,01544561 0,05940619 ! forebrain development GO:0030900 131 80 1,000 0,01581777 0,060736 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01619377 0,06207611 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,01657359 0,0634264 GO:0060348|bone development, ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01669942 0,06380176 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01669942 0,06369596 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01669942 0,0635905 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01669942 0,06348539 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01669942 0,06338063 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01669942 0,06327621 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01669942 0,06317214 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01669942 0,06306841 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01669942 0,06296502 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01669942 0,06286197 ! reproductive behavior GO:0019098 12 7 0,000 0,01669942 0,06275925 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01669942 0,06265687 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01669942 0,06255482 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01669942 0,06245311 ! oligopeptide transport GO:0006857 11 7 0,000 0,01669942 0,06235172 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01669942 0,06225067 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01669942 0,06214994 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,01669942 0,06204953 ! pericardium development GO:0060039 8 7 0,000 0,01669942 0,06194945 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01669942 0,0618497 ! fibril organization GO:0043206 13 7 0,000 0,01669942 0,06175026 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01669942 0,06165114 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01669942 0,06155234 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01669942 0,06145386 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01669942 0,06135569 ! lipoprotein transport GO:0042953 9 7 0,000 0,01669942 0,06125783 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01669942 0,06116029 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01669942 0,06106305 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01669942 0,06096613 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01669942 0,06086951 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01669942 0,0607732 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01669942 0,06067719 ! chemosensory behavior GO:0007635 9 7 0,000 0,01669942 0,06058148 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01669942 0,06048608 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01669942 0,06039098 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01669942 0,06029617 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01669942 0,06020166 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01669942 0,06010745 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01669942 0,06001353 ! reflex GO:0060004 12 7 0,000 0,01669942 0,05991991 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01669942 0,05982658 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01669942 0,05973353 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01669942 0,05964078 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01669942 0,05954831 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01669942 0,05945613 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01669942 0,05936424 ! spinal cord patterning GO:0021511 7 7 0,000 0,01669942 0,05927263 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01669942 0,0591813 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01669942 0,05909025 ! adrenal gland development GO:0030325 17 7 0,000 0,01669942 0,05899948 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01669942 0,05890899 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01669942 0,05881878 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01669942 0,05872884 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01669942 0,05863918 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01669942 0,05854979 ! endosome organization GO:0007032 10 7 0,000 0,01669942 0,05846067 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01669942 0,05837183 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01669942 0,05828325 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01669942 0,05819494 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01669942 0,0581069 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01669942 0,05801913 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01669942 0,05793162 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01669942 0,05784437 ! galactose metabolic process GO:0006012 10 7 0,000 0,01669942 0,05775739 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01669942 0,05767066 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01669942 0,0575842 ! organ growth GO:0035265 11 7 0,000 0,01669942 0,057498 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01669942 0,05741205 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01669942 0,05732636 ! retinol metabolic process GO:0042572 9 7 0,000 0,01669942 0,05724093 ! behavioral fear response GO:0001662 13 7 0,000 0,01669942 0,05715575 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01669942 0,05707082 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01669942 0,05698614 ! rRNA modification GO:0000154 12 7 0,000 0,01669942 0,05690172 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01669942 0,05681755 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01669942 0,05673362 ! response to UV-B GO:0010224 11 7 0,000 0,01669942 0,05664994 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01669942 0,05656651 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01669942 0,05648333 ! intermediate filament organization GO:0045109 11 7 0,000 0,01669942 0,05640038 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01669942 0,05631769 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01669942 0,05623523 ! fibrinolysis GO:0042730 9 7 0,000 0,01669942 0,05615301 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01669942 0,05607104 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01669942 0,0559893 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01669942 0,0559078 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01669942 0,05582654 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01669942 0,05574552 ! response to tropane GO:0014073 13 7 0,000 0,01669942 0,05566473 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01669942 0,05558417 ! melanosome localization GO:0032400 10 7 0,000 0,01669942 0,05550385 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01669942 0,05542375 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01669942 0,05534389 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01669942 0,05526426 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01669942 0,05518486 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01669942 0,05510568 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01669942 0,05502674 ! mast cell activation GO:0045576 9 7 0,000 0,01669942 0,05494801 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01669942 0,05486952 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01669942 0,05479124 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01669942 0,05471319 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01669942 0,05463536 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01669942 0,05455776 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01669942 0,05448037 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01669942 0,0544032 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01669942 0,05432625 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01669942 0,05424952 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01669942 0,05417301 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01669942 0,05409671 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01669942 0,05402062 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01669942 0,05394475 ! response to tumor cell GO:0002347 12 7 0,000 0,01669942 0,05386909 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01669942 0,05379364 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01669942 0,05371841 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01669942 0,05364338 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01669942 0,05356857 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01669942 0,05349396 ! diuresis GO:0030146 12 7 0,000 0,01669942 0,05341956 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01669942 0,05334536 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01669942 0,05327138 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01669942 0,05319759 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01669942 0,05312401 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01669942 0,05305064 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01669942 0,05297746 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01669942 0,05290449 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01669942 0,05283172 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01669942 0,05275915 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01669942 0,05268678 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01669942 0,0526146 ! lymph node development GO:0048535 9 7 0,000 0,01669942 0,05254263 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01669942 0,05247085 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01669942 0,05239927 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01669942 0,05232788 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01669942 0,05225668 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01669942 0,05218568 ! ATP catabolic process GO:0006200 10 7 0,000 0,01669942 0,05211487 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01669942 0,05204426 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01669942 0,05197383 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01669942 0,0519036 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01669942 0,05183355 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01669942 0,05176369 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01669942 0,05169403 ! muscle adaptation GO:0043500 12 7 0,000 0,01669942 0,05162454 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01669942 0,05155525 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01669942 0,05148614 ! retina homeostasis GO:0001895 9 7 0,000 0,01669942 0,05141722 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01669942 0,05134848 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01669942 0,05127992 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01669942 0,05121155 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01669942 0,05114336 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01669942 0,05107535 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01669942 0,05100752 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01669942 0,05093987 ! cell cycle arrest GO:0007050 150 86 1,000 0,01813075 0,05523276 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 1,000 0,01852941 0,05637255 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 1,000 0,01893178 0,05752059 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01906272 0,05784201 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01906272 0,0577658 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01906272 0,0576898 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01906272 0,05761399 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01906272 0,05753838 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01906272 0,05746297 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01906272 0,05738776 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01906272 0,05731274 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01906272 0,05723792 ! phosphate transport GO:0006817 10 8 0,000 0,01906272 0,05716329 ! N-glycan processing GO:0006491 12 8 0,000 0,01906272 0,05708886 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01906272 0,05701462 ! UTP metabolic process GO:0046051 8 8 0,000 0,01906272 0,05694058 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01906272 0,05686673 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01906272 0,05679306 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01906272 0,05671959 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01906272 0,05664631 ! succinate metabolic process GO:0006105 14 8 0,000 0,01906272 0,05657322 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01906272 0,05650032 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01906272 0,0564276 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01906272 0,05635507 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01906272 0,05628273 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01906272 0,05621057 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01906272 0,0561386 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01906272 0,05606681 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01906272 0,05599521 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01906272 0,05592378 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01906272 0,05585254 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01906272 0,05578148 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01906272 0,0557106 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01906272 0,05563991 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01906272 0,05556939 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01906272 0,05549905 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01906272 0,05542888 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01906272 0,0553589 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01906272 0,05528909 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01906272 0,05521945 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01906272 0,05514999 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01906272 0,05508071 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01906272 0,0550116 ! melanin metabolic process GO:0006582 12 8 0,000 0,01906272 0,05494266 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01906272 0,0548739 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01906272 0,05480531 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01906272 0,05473689 ! macrophage activation GO:0042116 12 8 0,000 0,01906272 0,05466864 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01906272 0,05460056 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01906272 0,05453264 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01906272 0,0544649 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01906272 0,05439733 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01906272 0,05432992 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01906272 0,05426268 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01906272 0,05419561 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01906272 0,0541287 ! ruffle organization GO:0031529 11 8 0,000 0,01906272 0,05406196 ! osteoblast development GO:0002076 13 8 0,000 0,01906272 0,05399538 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01906272 0,05392896 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01906272 0,05386271 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01906272 0,05379662 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01906272 0,05373069 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01906272 0,05366493 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01906272 0,05359932 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01906272 0,05353388 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01906272 0,05346859 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01906272 0,05340347 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01906272 0,0533385 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01906272 0,05327369 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01906272 0,05320904 ! segment specification GO:0007379 10 8 0,000 0,01906272 0,05314454 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01906272 0,0530802 ! cellular extravasation GO:0045123 11 8 0,000 0,01906272 0,05301602 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01906272 0,05295199 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01906272 0,05288811 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01906272 0,05282439 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01906272 0,05276083 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01906272 0,05269741 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01906272 0,05263415 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01906272 0,05257104 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01906272 0,05250808 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01906272 0,05244527 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01906272 0,05238261 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01906272 0,0523201 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01906272 0,05225774 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01906272 0,05219553 ! icosanoid secretion GO:0032309 12 8 0,000 0,01906272 0,05213347 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01906272 0,05207155 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01906272 0,05200978 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01906272 0,05194816 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01906272 0,05188668 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01906272 0,05182535 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01906272 0,05176416 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01906272 0,05170312 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01906272 0,05164222 ! sterol catabolic process GO:0016127 9 8 0,000 0,01906272 0,05158147 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01906272 0,05152085 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01906272 0,05146038 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01906272 0,05140005 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01906272 0,05133987 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01906272 0,05127982 ! prophase GO:0051324 11 8 0,000 0,01906272 0,05121991 ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01906272 0,05116015 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01906272 0,05110052 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01906272 0,05104103 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01906272 0,05098168 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01906272 0,05092247 ! hormone catabolic process GO:0042447 13 8 0,000 0,01906272 0,05086339 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01906272 0,05080446 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01906272 0,05074565 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01906272 0,05068699 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01906272 0,05062846 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01906272 0,05057006 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01906272 0,0505118 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01906272 0,05045368 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01906272 0,05039568 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01906272 0,05033783 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01906272 0,0502801 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01906272 0,0502225 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01906272 0,05016504 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01906272 0,05010771 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01906272 0,05005051 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01906272 0,04999344 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01906272 0,0499365 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 1,000 0,01933783 0,05059956 ! ATP metabolic process GO:0046034 137 91 1,000 0,02016093 0,05269334 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,02057794 0,05372219 ! positive regulation of immune response GO:0050778 121 92 1,000 0,02057794 0,05366128 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02142047 0,0557951 ! regulation of developmental growth GO:0048638 13 9 0,000 0,02142047 0,05573199 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,02142047 0,05566901 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02142047 0,05560618 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02142047 0,05554349 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02142047 0,05548094 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02142047 0,05541853 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02142047 0,05535627 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02142047 0,05529414 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02142047 0,05523215 ! GTP metabolic process GO:0046039 9 9 0,000 0,02142047 0,0551703 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02142047 0,05510859 ! social behavior GO:0035176 14 9 0,000 0,02142047 0,05504701 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02142047 0,05498558 ! artery development GO:0060840 19 9 0,000 0,02142047 0,05492428 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02142047 0,05486311 ! regulation of glycolysis GO:0006110 15 9 0,000 0,02142047 0,05480209 ! response to pain GO:0048265 16 9 0,000 0,02142047 0,0547412 ! protein complex disassembly GO:0043241 17 9 0,000 0,02142047 0,05468044 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02142047 0,05461982 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02142047 0,05455933 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02142047 0,05449898 ! lung alveolus development GO:0048286 17 9 0,000 0,02142047 0,05443876 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02142047 0,05437867 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02142047 0,05431872 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02142047 0,05425889 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02142047 0,0541992 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02142047 0,05413964 ! protein targeting to ER GO:0045047 19 9 0,000 0,02142047 0,05408022 ! T cell selection GO:0045058 18 9 0,000 0,02142047 0,05402092 ! endoderm development GO:0007492 12 9 0,000 0,02142047 0,05396175 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02142047 0,05390271 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02142047 0,0538438 ! arginine catabolic process GO:0006527 10 9 0,000 0,02142047 0,05378502 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02142047 0,05372636 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02142047 0,05366784 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02142047 0,05360944 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02142047 0,05355117 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02142047 0,05349303 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02142047 0,05343501 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02142047 0,05337711 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02142047 0,05331935 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02142047 0,0532617 ! mannose metabolic process GO:0006013 9 9 0,000 0,02142047 0,05320419 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02142047 0,05314679 ! receptor clustering GO:0043113 15 9 0,000 0,02142047 0,05308952 ! epithelial cell development GO:0002064 10 9 0,000 0,02142047 0,05303238 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02142047 0,05297535 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02142047 0,05291845 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02142047 0,05286167 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02142047 0,05280501 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02142047 0,05274848 ! motor axon guidance GO:0008045 14 9 0,000 0,02142047 0,05269206 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02142047 0,05263577 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02142047 0,05257959 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02142047 0,05252354 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02142047 0,0524676 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02142047 0,05241178 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02142047 0,05235609 ! DNA ligation GO:0006266 14 9 0,000 0,02142047 0,05230051 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02142047 0,05224504 ! response to amine stimulus GO:0014075 13 9 0,000 0,02142047 0,0521897 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02142047 0,05213447 ! erythrocyte development GO:0048821 11 9 0,000 0,02142047 0,05207936 ! renal water homeostasis GO:0003091 14 9 0,000 0,02142047 0,05202437 ! postreplication repair GO:0006301 11 9 0,000 0,02142047 0,05196949 ! mRNA cleavage GO:0006379 13 9 0,000 0,02142047 0,05191473 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02142047 0,05186008 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02142047 0,05180555 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02142047 0,05175113 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02142047 0,05169683 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02142047 0,05164264 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02142047 0,05158856 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02142047 0,0515346 ! acid secretion GO:0046717 14 9 0,000 0,02142047 0,05148075 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02142047 0,05142701 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02142047 0,05137339 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02142047 0,05131987 ! purine base metabolic process GO:0006144 18 9 0,000 0,02142047 0,05126647 ! oocyte differentiation GO:0009994 12 9 0,000 0,02142047 0,05121318 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02142047 0,05116 ! spleen development GO:0048536 15 9 0,000 0,02142047 0,05110693 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02142047 0,05105397 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02142047 0,05100111 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02142047 0,05094837 ! detection of calcium ion GO:0005513 13 9 0,000 0,02142047 0,05089574 ! blastocyst formation GO:0001825 12 9 0,000 0,02142047 0,05084322 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02142047 0,0507908 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02142047 0,05073849 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02142047 0,05068629 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02142047 0,0506342 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02142047 0,05058221 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02142047 0,05053033 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02142047 0,05047856 ! prepulse inhibition GO:0060134 14 9 0,000 0,02142047 0,05042689 ! embryonic placenta development GO:0001892 12 9 0,000 0,02142047 0,05037533 ! insulin secretion GO:0030073 17 9 0,000 0,02142047 0,05032388 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02142047 0,05027253 ! response to nicotine GO:0035094 16 9 0,000 0,02142047 0,05022128 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02142047 0,05017014 ! nucleus localization GO:0051647 15 9 0,000 0,02142047 0,0501191 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02142047 0,05006817 ! response to oxidative stress GO:0006979 141 94 1,000 0,02142277 0,05002271 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,02359709 0,05504391 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02377269 0,05539735 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02377269 0,05534128 ! neuron fate specification GO:0048665 11 10 0,000 0,02377269 0,05528532 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02377269 0,05522948 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02377269 0,05517375 ! thyroid gland development GO:0030878 19 10 0,000 0,02377269 0,05511813 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02377269 0,05506262 ! synapsis GO:0007129 13 10 0,000 0,02377269 0,05500723 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02377269 0,05495194 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02377269 0,05489677 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02377269 0,05484171 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02377269 0,05478676 ! sulfate transport GO:0008272 12 10 0,000 0,02377269 0,05473191 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02377269 0,05467718 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02377269 0,05462256 ! androgen metabolic process GO:0008209 13 10 0,000 0,02377269 0,05456805 ! phospholipid efflux GO:0033700 16 10 0,000 0,02377269 0,05451364 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,02377269 0,05445935 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02377269 0,05440516 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02377269 0,05435108 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02377269 0,0542971 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02377269 0,05424324 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02377269 0,05418948 ! pathogenesis GO:0009405 13 10 0,000 0,02377269 0,05413582 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02377269 0,05408228 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02377269 0,05402884 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02377269 0,0539755 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02377269 0,05392227 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02377269 0,05386915 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02377269 0,05381612 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02377269 0,05376321 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02377269 0,0537104 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02377269 0,05365769 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02377269 0,05360508 ! response to X-ray GO:0010165 16 10 0,000 0,02377269 0,05355258 ! B cell proliferation GO:0042100 14 10 0,000 0,02377269 0,05350018 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02377269 0,05344788 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02377269 0,05339569 ! forebrain cell migration GO:0021885 17 10 0,000 0,02377269 0,05334359 ! lipid digestion GO:0044241 15 10 0,000 0,02377269 0,0532916 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02377269 0,05323971 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02377269 0,05318792 ! UV protection GO:0009650 14 10 0,000 0,02377269 0,05313623 ! entry into host cell GO:0030260 20 10 0,000 0,02377269 0,05308464 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02377269 0,05303315 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02377269 0,05298177 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02377269 0,05293048 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02377269 0,05287929 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02377269 0,0528282 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02377269 0,0527772 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02377269 0,05272631 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02377269 0,05267551 ! regulation of organ growth GO:0046620 11 10 0,000 0,02377269 0,05262481 ! response to dsRNA GO:0043331 18 10 0,000 0,02377269 0,05257421 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02377269 0,05252371 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02377269 0,0524733 ! embryonic axis specification GO:0000578 12 10 0,000 0,02377269 0,05242299 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02377269 0,05237278 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02377269 0,05232266 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02377269 0,05227264 ! cranial nerve development GO:0021545 12 10 0,000 0,02377269 0,05222271 ! fucose catabolic process GO:0019317 16 10 0,000 0,02377269 0,05217288 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02377269 0,05212315 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02377269 0,05207351 ! protein sumoylation GO:0016925 12 10 0,000 0,02377269 0,05202396 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02377269 0,05197451 ! zymogen activation GO:0031638 14 10 0,000 0,02377269 0,05192515 ! salivary gland development GO:0007431 22 10 0,000 0,02377269 0,05187588 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02377269 0,05182671 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02377269 0,05177763 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02377269 0,05172865 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02377269 0,05167976 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02377269 0,05163096 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02377269 0,05158225 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02377269 0,05153363 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02377269 0,05148511 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02377269 0,05143667 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02377269 0,05138833 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02377269 0,05134008 ! detection of bacterium GO:0016045 10 10 0,000 0,02377269 0,05129192 ! embryonic gut development GO:0048566 11 10 0,000 0,02377269 0,05124384 ! activation of innate immune response GO:0002218 10 10 0,000 0,02377269 0,05119586 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02377269 0,05114797 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02377269 0,05110017 ! developmental induction GO:0031128 13 10 0,000 0,02377269 0,05105246 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02377269 0,05100483 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02377269 0,0509573 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02377269 0,05090985 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 1,000 0,02404247 0,0514397 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,02404247 0,0513919 ! rRNA transcription GO:0009303 17 11 0,000 0,02611939 0,05577957 ! respiratory burst GO:0045730 14 11 0,000 0,02611939 0,05572782 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02611939 0,05567618 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02611939 0,05562462 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02611939 0,05557317 ! virus-host interaction GO:0019048 17 11 0,000 0,02611939 0,05552181 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02611939 0,05547054 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02611939 0,05541937 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02611939 0,05536829 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02611939 0,0553173 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02611939 0,05526641 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02611939 0,05521562 ! mating GO:0007618 14 11 0,000 0,02611939 0,05516492 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02611939 0,05511431 ! T cell proliferation GO:0042098 20 11 0,000 0,02611939 0,05506379 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02611939 0,05501336 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02611939 0,05496303 ! bone resorption GO:0045453 16 11 0,000 0,02611939 0,05491279 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02611939 0,05486264 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02611939 0,05481258 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02611939 0,05476262 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02611939 0,05471274 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02611939 0,05466296 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02611939 0,05461327 ! syncytium formation GO:0006949 15 11 0,000 0,02611939 0,05456366 ! plasma membrane organization GO:0007009 18 11 0,000 0,02611939 0,05451415 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02611939 0,05446473 ! focal adhesion formation GO:0048041 24 11 0,000 0,02611939 0,05441539 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02611939 0,05436615 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02611939 0,05431699 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02611939 0,05426793 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02611939 0,05421895 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02611939 0,05417006 ! adult heart development GO:0007512 11 11 0,000 0,02611939 0,05412125 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02611939 0,05407254 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02611939 0,05402391 ! temperature homeostasis GO:0001659 16 11 0,000 0,02611939 0,05397538 ! L-glutamate transport GO:0015813 16 11 0,000 0,02611939 0,05392692 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02611939 0,05387856 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02611939 0,05383028 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02611939 0,05378209 ! stem cell development GO:0048864 29 11 0,000 0,02611939 0,05373398 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02611939 0,05368596 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02611939 0,05363803 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02611939 0,05359018 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02611939 0,05354242 ! vasoconstriction GO:0042310 15 11 0,000 0,02611939 0,05349474 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02611939 0,05344715 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02611939 0,05339964 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02611939 0,05335221 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02611939 0,05330487 ! ribosome assembly GO:0042255 13 11 0,000 0,02611939 0,05325762 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02611939 0,05321045 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02611939 0,05316336 ! chromatin silencing GO:0006342 19 11 0,000 0,02611939 0,05311635 ! nucleosome positioning GO:0016584 13 11 0,000 0,02611939 0,05306943 ! T cell homeostasis GO:0043029 20 11 0,000 0,02611939 0,05302259 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02611939 0,05297583 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02611939 0,05292916 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02611939 0,05288256 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02611939 0,05283605 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02611939 0,05278962 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02611939 0,05274328 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02611939 0,05269701 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02611939 0,05265083 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02611939 0,05260472 ! male genitalia development GO:0030539 13 11 0,000 0,02611939 0,0525587 ! cholesterol efflux GO:0033344 19 11 0,000 0,02611939 0,05251276 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02611939 0,05246689 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02611939 0,05242111 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02611939 0,05237541 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02611939 0,05232978 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02611939 0,05228424 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02611939 0,05223878 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02611939 0,05219339 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02611939 0,05214808 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02611939 0,05210286 ! lysogeny GO:0030069 18 11 0,000 0,02611939 0,05205771 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02611939 0,05201263 ! acrosome reaction GO:0007340 13 11 0,000 0,02611939 0,05196764 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02611939 0,05192273 ! lactation GO:0007595 20 12 0,000 0,02846058 0,05652793 ! reproductive cellular process GO:0048610 14 12 0,000 0,02846058 0,05647915 ! tRNA modification GO:0006400 14 12 0,000 0,02846058 0,05643046 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02846058 0,05638186 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02846058 0,05633334 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02846058 0,0562849 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02846058 0,05623654 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02846058 0,05618827 ! non-recombinational repair GO:0000726 19 12 0,000 0,02846058 0,05614008 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02846058 0,05609198 ! peroxisomal transport GO:0043574 21 12 0,000 0,02846058 0,05604395 ! cartilage condensation GO:0001502 18 12 0,000 0,02846058 0,05599601 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02846058 0,05594815 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02846058 0,05590037 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02846058 0,05585268 ! heart looping GO:0001947 15 12 0,000 0,02846058 0,05580506 ! palate development GO:0060021 15 12 0,000 0,02846058 0,05575753 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,02846058 0,05571007 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02846058 0,0556627 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02846058 0,05561541 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02846058 0,0555682 ! arginine metabolic process GO:0006525 13 12 0,000 0,02846058 0,05552107 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02846058 0,05547401 ! methionine metabolic process GO:0006555 13 12 0,000 0,02846058 0,05542704 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02846058 0,05538015 ! Golgi organization GO:0007030 18 12 0,000 0,02846058 0,05533334 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02846058 0,0552866 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02846058 0,05523995 ! monoamine transport GO:0015844 13 12 0,000 0,02846058 0,05519337 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02846058 0,05514687 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02846058 0,05510045 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02846058 0,05505411 ! L-amino acid transport GO:0015807 20 12 0,000 0,02846058 0,05500785 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02846058 0,05496166 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02846058 0,05491555 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02846058 0,05486952 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02846058 0,05482357 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02846058 0,05477769 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02846058 0,05473189 ! cerebellum development GO:0021549 13 12 0,000 0,02846058 0,05468616 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02846058 0,05464052 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02846058 0,05459494 ! histone methylation GO:0016571 15 12 0,000 0,02846058 0,05454945 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02846058 0,05450403 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02846058 0,05445868 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02846058 0,05441341 ! response to gamma radiation GO:0010332 20 12 0,000 0,02846058 0,05436822 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02846058 0,0543231 ! intestinal absorption GO:0050892 19 12 0,000 0,02846058 0,05427806 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02846058 0,05423309 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02846058 0,05418819 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02846058 0,05414337 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02846058 0,05409863 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02846058 0,05405395 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02846058 0,05400935 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02846058 0,05396483 ! microspike assembly GO:0030035 23 12 0,000 0,02846058 0,05392038 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02846058 0,053876 ! response to cold GO:0009409 14 12 0,000 0,02846058 0,05383169 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,03079628 0,05820168 ! cGMP metabolic process GO:0046068 16 13 0,000 0,03079628 0,0581539 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,03079628 0,05810619 ! water transport GO:0006833 17 13 0,000 0,03079628 0,05805856 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,03079628 0,05801101 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,03079628 0,05796354 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,03079628 0,05791614 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,03079628 0,05786883 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,03079628 0,05782159 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,03079628 0,05777442 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,03079628 0,05772734 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,03079628 0,05768033 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,03079628 0,0576334 ! response to hexose stimulus GO:0009746 19 13 0,000 0,03079628 0,05758654 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,03079628 0,05753976 ! glutamate metabolic process GO:0006536 18 13 0,000 0,03079628 0,05749306 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,03079628 0,05744643 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,03079628 0,05739987 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,03079628 0,0573534 ! NAD metabolic process GO:0019674 21 13 0,000 0,03079628 0,05730699 ! exocrine system development GO:0035272 27 13 0,000 0,03079628 0,05726067 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,03079628 0,05721441 ! bone mineralization GO:0030282 15 13 0,000 0,03079628 0,05716824 ! regulation of exocytosis GO:0017157 17 13 0,000 0,03079628 0,05712213 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,03079628 0,0570761 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,03079628 0,05703015 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,03079628 0,05698427 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,03079628 0,05693846 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,03079628 0,05689273 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,03079628 0,05684707 ! genitalia development GO:0048806 15 13 0,000 0,03079628 0,05680148 ! regulation of cellular pH GO:0030641 20 13 0,000 0,03079628 0,05675596 ! cellular pigmentation GO:0033059 24 13 0,000 0,03079628 0,05671052 ! tissue regeneration GO:0042246 21 13 0,000 0,03079628 0,05666516 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,03079628 0,05661986 ! cofactor transport GO:0051181 19 13 0,000 0,03079628 0,05657464 ! NADP metabolic process GO:0006739 18 13 0,000 0,03079628 0,05652948 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,03079628 0,05648441 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,03079628 0,0564394 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03079628 0,05639446 ! gas transport GO:0015669 18 13 0,000 0,03079628 0,0563496 ! regulation of RNA stability GO:0043487 28 13 0,000 0,03079628 0,0563048 ! heme biosynthetic process GO:0006783 20 13 0,000 0,03079628 0,05626008 ! regulation of axon extension GO:0030516 23 13 0,000 0,03079628 0,05621543 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,03079628 0,05617085 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,03079628 0,05612634 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,03079628 0,0560819 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,03079628 0,05603753 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,03079628 0,05599324 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,03079628 0,05594901 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,0331265 0,06013492 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,0331265 0,06008749 ! superoxide anion generation GO:0042554 18 14 0,000 0,0331265 0,06004014 ! neuron maturation GO:0042551 21 14 0,000 0,0331265 0,05999287 ! regulation of S phase GO:0033261 18 14 0,000 0,0331265 0,05994567 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,0331265 0,05989854 ! myotube differentiation GO:0014902 21 14 0,000 0,0331265 0,05985149 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,0331265 0,05980451 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,0331265 0,0597576 ! inositol metabolic process GO:0006020 20 14 0,000 0,0331265 0,05971077 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,0331265 0,05966401 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,0331265 0,05961733 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,0331265 0,05957071 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,0331265 0,05952417 ! gene silencing by RNA GO:0031047 20 14 0,000 0,0331265 0,05947771 ! response to cAMP GO:0051591 19 14 0,000 0,0331265 0,05943131 ! startle response GO:0001964 21 14 0,000 0,0331265 0,05938499 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,0331265 0,05933874 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,0331265 0,05929256 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0331265 0,05924646 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,0331265 0,05920042 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,0331265 0,05915446 ! glycine metabolic process GO:0006544 22 14 0,000 0,0331265 0,05910857 ! pituitary gland development GO:0021983 23 14 0,000 0,0331265 0,05906275 ! cellular response to starvation GO:0009267 21 14 0,000 0,0331265 0,059017 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,0331265 0,05897132 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,0331265 0,05892571 ! regulation of heart rate GO:0002027 23 14 0,000 0,0331265 0,05888017 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,0331265 0,0588347 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,0331265 0,05878931 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,0331265 0,05874398 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,0331265 0,05869872 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,0331265 0,05865354 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,0331265 0,05860842 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,0331265 0,05856337 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,0331265 0,05851839 ! axon cargo transport GO:0008088 27 14 0,000 0,0331265 0,05847348 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,0331265 0,05842864 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,0331265 0,05838386 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,0331265 0,05833916 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,0331265 0,05829452 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0331265 0,05824996 ! mRNA splice site selection GO:0006376 26 14 0,000 0,0331265 0,05820546 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,0331265 0,05816102 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,0331265 0,05811666 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,0331265 0,05807236 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,0331265 0,05802814 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,0331265 0,05798397 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,0331265 0,05793988 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,0331265 0,05789585 ! muscle maintenance GO:0046716 19 14 0,000 0,0331265 0,05785189 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,0331265 0,057808 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,0331265 0,05776417 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,0331265 0,05772041 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,0331265 0,05767672 ! cell killing GO:0001906 20 14 0,000 0,0331265 0,05763309 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,0331265 0,05758953 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,0331265 0,05754603 ! cilium assembly GO:0042384 20 14 0,000 0,0331265 0,0575026 ! peptide hormone secretion GO:0030072 23 14 0,000 0,0331265 0,05745923 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,03545124 0,06144526 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03545124 0,06139899 ! metencephalon development GO:0022037 19 15 0,000 0,03545124 0,06135279 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03545124 0,06130666 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,03545124 0,0612606 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03545124 0,06121461 ! skin development GO:0043588 25 15 0,000 0,03545124 0,06116869 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,03545124 0,06112283 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03545124 0,06107705 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03545124 0,06103133 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03545124 0,06098569 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03545124 0,06094011 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03545124 0,06089459 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,03545124 0,06084915 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03545124 0,06080377 ! adult walking behavior GO:0007628 25 15 0,000 0,03545124 0,06075847 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03545124 0,06071323 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03545124 0,06066805 ! myoblast differentiation GO:0045445 27 15 0,000 0,03545124 0,06062295 ! centrosome cycle GO:0007098 16 15 0,000 0,03545124 0,06057791 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,03545124 0,06053293 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,03545124 0,06048803 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03545124 0,06044319 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03545124 0,06039842 ! response to osmotic stress GO:0006970 22 15 0,000 0,03545124 0,06035371 ! vesicle coating GO:0006901 25 15 0,000 0,03545124 0,06030907 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03545124 0,06026449 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,03545124 0,06021999 ! peptide secretion GO:0002790 27 15 0,000 0,03545124 0,06017554 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,03545124 0,06013117 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,03545124 0,06008685 ! neuron recognition GO:0008038 22 15 0,000 0,03545124 0,06004261 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03545124 0,05999843 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03545124 0,05995431 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03545124 0,05991026 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03545124 0,05986627 ! biomineral formation GO:0031214 18 15 0,000 0,03545124 0,05982235 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03545124 0,05977849 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03545124 0,0597347 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03545124 0,05969097 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03545124 0,0596473 ! organic cation transport GO:0015695 19 15 0,000 0,03545124 0,0596037 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03545124 0,05956016 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,03545124 0,05951669 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03545124 0,05947328 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03545124 0,05942993 ! defense response to virus GO:0051607 27 15 0,000 0,03545124 0,05938664 ! peptide hormone processing GO:0016486 19 15 0,000 0,03545124 0,05934342 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,03545124 0,05930026 ! protein secretion GO:0009306 27 16 0,000 0,03777053 0,06313389 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03777053 0,06308804 ! hormone secretion GO:0046879 25 16 0,000 0,03777053 0,06304226 ! bone remodeling GO:0046849 24 16 0,000 0,03777053 0,06299654 ! endothelial cell migration GO:0043542 22 16 0,000 0,03777053 0,06295089 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03777053 0,06290531 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03777053 0,06285979 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03777053 0,06281434 ! glial cell development GO:0021782 24 16 0,000 0,03777053 0,06276895 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03777053 0,06272363 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03777053 0,06267838 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03777053 0,06263319 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03777053 0,06258806 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03777053 0,062543 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,03777053 0,06249801 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03777053 0,06245308 ! fructose metabolic process GO:0006000 20 16 0,000 0,03777053 0,06240821 ! regulation of protein binding GO:0043393 27 16 0,000 0,03777053 0,06236341 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03777053 0,06231867 ! protein export from nucleus GO:0006611 24 16 0,000 0,03777053 0,062274 ! negative regulation of immune response GO:0050777 28 16 0,000 0,03777053 0,06222939 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03777053 0,06218485 ! DNA replication initiation GO:0006270 25 16 0,000 0,03777053 0,06214036 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03777053 0,06209595 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03777053 0,06205159 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03777053 0,0620073 ! diencephalon development GO:0021536 25 16 0,000 0,03777053 0,06196307 ! oogenesis GO:0048477 23 16 0,000 0,03777053 0,06191891 ! neural crest cell migration GO:0001755 24 16 0,000 0,03777053 0,06187481 ! G1 phase GO:0051318 27 16 0,000 0,03777053 0,06183077 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03777053 0,06178679 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03777053 0,06174288 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03777053 0,06169903 ! steroid catabolic process GO:0006706 22 16 0,000 0,03777053 0,06165524 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03777053 0,06161151 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,03777053 0,06156785 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03777053 0,06152424 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03777053 0,0614807 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03777053 0,06143722 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03777053 0,0613938 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03777053 0,06135044 ! nerve development GO:0021675 18 16 0,000 0,03777053 0,06130715 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,03777053 0,06126391 ! negative regulation of translation GO:0017148 22 16 0,000 0,03777053 0,06122074 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,04008438 0,06492541 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,04008438 0,06487972 ! negative regulation of defense response GO:0031348 19 17 0,000 0,04008438 0,06483409 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,04008438 0,06478853 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,04008438 0,06474303 ! glycerol metabolic process GO:0006071 20 17 0,000 0,04008438 0,0646976 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,04008438 0,06465223 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,04008438 0,06460692 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,04008438 0,06456168 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,04008438 0,0645165 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,04008438 0,06447138 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,04008438 0,06442633 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,04008438 0,06438134 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,04008438 0,06433641 ! memory GO:0007613 25 17 0,000 0,04008438 0,06429155 ! keratinization GO:0031424 17 17 0,000 0,04008438 0,06424674 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,04008438 0,064202 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,04008438 0,06415733 ! retinoid metabolic process GO:0001523 22 17 0,000 0,04008438 0,06411271 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,04008438 0,06406816 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,04008438 0,06402366 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,04008438 0,06397923 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,04008438 0,06393487 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,04008438 0,06389056 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,04008438 0,06384631 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,04008438 0,06380213 ! membrane budding GO:0006900 29 17 0,000 0,04008438 0,06375801 ! heme metabolic process GO:0042168 27 17 0,000 0,04008438 0,06371394 ! neuromuscular junction development GO:0007528 23 17 0,000 0,04008438 0,06366994 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,04008438 0,063626 ! body fluid secretion GO:0007589 27 17 0,000 0,04008438 0,06358212 ! stem cell differentiation GO:0048863 36 17 0,000 0,04008438 0,0635383 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,04008438 0,06349454 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,04008438 0,06345084 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,04008438 0,06340721 ! sensory perception of pain GO:0019233 23 17 0,000 0,04008438 0,06336363 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,04008438 0,06332011 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,04008438 0,06327665 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,04008438 0,06323325 ! synaptogenesis GO:0007416 24 17 0,000 0,04008438 0,06318991 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,04008438 0,06314663 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,04008438 0,06310341 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,04008438 0,06306024 ! cell-cell junction organization GO:0045216 25 17 0,000 0,04008438 0,06301714 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,04008438 0,0629741 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,04008438 0,06293111 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,04008438 0,06288818 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,04008438 0,06284531 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,04008438 0,0628025 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,04008438 0,06275975 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,0423928 0,06632886 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,0423928 0,06628377 ! positive regulation of translation GO:0045727 28 18 0,000 0,0423928 0,06623874 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,0423928 0,06619377 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,0423928 0,06614887 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,0423928 0,06610402 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,0423928 0,06605923 ! cAMP metabolic process GO:0046058 33 18 0,000 0,0423928 0,06601451 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,0423928 0,06596984 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,0423928 0,06592524 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,0423928 0,0658807 ! axis specification GO:0009798 26 18 0,000 0,0423928 0,06583621 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,0423928 0,06579179 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,0423928 0,06574742 ! pancreas development GO:0031016 26 18 0,000 0,0423928 0,06570312 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,0423928 0,06565887 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,0423928 0,06561469 ! glutamine metabolic process GO:0006541 23 18 0,000 0,0423928 0,06557056 ! response to retinoic acid GO:0032526 25 18 0,000 0,0423928 0,0655265 ! pigmentation during development GO:0048066 31 18 0,000 0,0423928 0,06548249 ! central nervous system neuron development GO:0021954 30 18 0,000 0,0423928 0,06543854 ! fucose metabolic process GO:0006004 26 18 0,000 0,0423928 0,06539465 ! response to fungus GO:0009620 19 18 0,000 0,0423928 0,06535082 ! peptide cross-linking GO:0018149 31 18 0,000 0,0423928 0,06530705 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,0423928 0,06526334 ! heart process GO:0003015 27 18 0,000 0,0423928 0,06521969 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,0423928 0,06517609 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,0423928 0,06513255 ! visual learning GO:0008542 35 18 0,000 0,0423928 0,06508907 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,0423928 0,06504565 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,0423928 0,06500229 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,0423928 0,06495898 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,0423928 0,06491573 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,0423928 0,06487254 ! vitamin transport GO:0051180 24 18 0,000 0,0423928 0,06482941 ! hormone transport GO:0009914 27 18 0,000 0,0423928 0,06478633 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,0423928 0,06474331 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,0423928 0,06470035 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,0423928 0,06465745 ! cell-cell recognition GO:0009988 20 18 0,000 0,0423928 0,0646146 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,0423928 0,06457181 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,0423928 0,06452907 ! regulation of glucose import GO:0046324 21 18 0,000 0,0423928 0,06448639 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,0423928 0,06444377 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,0423928 0,06440121 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,0423928 0,0643587 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,0423928 0,06431625 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,04469579 0,06776554 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,04469579 0,06772089 ! positive regulation of ossification GO:0045778 30 19 0,000 0,04469579 0,06767631 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,04469579 0,06763179 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,04469579 0,06758732 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,04469579 0,06754292 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,04469579 0,06749857 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,04469579 0,06745428 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,04469579 0,06741004 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,04469579 0,06736587 ! regeneration GO:0031099 32 19 0,000 0,04469579 0,06732175 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,04469579 0,06727769 ! response to alkaloid GO:0043279 32 19 0,000 0,04469579 0,06723369 ! sensory perception of taste GO:0050909 23 19 0,000 0,04469579 0,06718975 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,04469579 0,06714586 ! smooth muscle contraction GO:0006939 36 19 0,000 0,04469579 0,06710203 ! peroxisome organization GO:0007031 29 19 0,000 0,04469579 0,06705826 ! digestive system process GO:0022600 30 19 0,000 0,04469579 0,06701455 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,04469579 0,06697089 ! response to vitamin A GO:0033189 26 19 0,000 0,04469579 0,06692729 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,04469579 0,06688375 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,04469579 0,06684026 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,04469579 0,06679683 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,04469579 0,06675345 ! response to starvation GO:0042594 30 19 0,000 0,04469579 0,06671013 ! sex determination GO:0007530 29 19 0,000 0,04469579 0,06666687 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,04469579 0,06662367 ! plasma membrane fusion GO:0045026 23 19 0,000 0,04469579 0,06658052 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,04469579 0,06653742 ! cytolysis GO:0019835 20 19 0,000 0,04469579 0,06649438 ! renal system process GO:0003014 35 19 0,000 0,04469579 0,0664514 ! vasodilation GO:0042311 33 19 0,000 0,04469579 0,06640847 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,04469579 0,0663656 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,04469579 0,06632279 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,04469579 0,06628002 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,04469579 0,06623732 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,04469579 0,06619467 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,04469579 0,06615207 ! sarcomere organization GO:0045214 23 19 0,000 0,04469579 0,06610953 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,04469579 0,06606704 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,04469579 0,06602461 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,04469579 0,06598223 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,04469579 0,06593991 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,04469579 0,06589764 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,04469579 0,06585542 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,04469579 0,06581326 ! protein stabilization GO:0050821 26 19 0,000 0,04469579 0,06577116 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,04699338 0,06910791 ! iron ion transport GO:0006826 37 20 0,000 0,04699338 0,06906375 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,04699338 0,06901965 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,04699338 0,0689756 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,04699338 0,06893161 ! response to vitamin GO:0033273 29 20 0,000 0,04699338 0,06888768 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,04699338 0,0688438 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,04699338 0,06879998 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,04699338 0,06875621 ! spinal cord development GO:0021510 31 20 0,000 0,04699338 0,0687125 ! response to ethanol GO:0045471 37 20 0,000 0,04699338 0,06866885 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,04699338 0,06862525 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,04699338 0,06858171 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,04699338 0,06853822 ! chromosome condensation GO:0030261 31 20 0,000 0,04699338 0,06849478 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,04699338 0,06845141 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,04699338 0,06840808 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,04699338 0,06836481 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,04699338 0,0683216 ! DNA modification GO:0006304 28 20 0,000 0,04699338 0,06827844 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,04699338 0,06823533 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,04699338 0,06819228 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,04699338 0,06814929 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,04699338 0,06810634 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,04699338 0,06806346 ! collagen catabolic process GO:0030574 25 20 0,000 0,04699338 0,06802062 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,04699338 0,06797784 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,04699338 0,06793512 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,04699338 0,06789244 ! alditol metabolic process GO:0019400 24 20 0,000 0,04699338 0,06784982 ! actin filament-based movement GO:0030048 34 20 0,000 0,04699338 0,06780726 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04928557 0,0710701 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04928557 0,07102557 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04928557 0,0709811 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04928557 0,07093668 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04928557 0,07089232 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04928557 0,07084801 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04928557 0,07080376 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04928557 0,07075956 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04928557 0,07071542 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04928557 0,07067133 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04928557 0,0706273 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04928557 0,07058332 ! phototransduction GO:0007602 25 21 0,000 0,04928557 0,0705394 ! dendrite development GO:0016358 35 21 0,000 0,04928557 0,07049553 ! visual behavior GO:0007632 39 21 0,000 0,04928557 0,07045172 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,04928557 0,07040796 ! ovarian follicle development GO:0001541 30 21 0,000 0,04928557 0,07036425 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04928557 0,0703206 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04928557 0,07027701 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04928557 0,07023347 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04928557 0,07018998 ! cell aging GO:0007569 32 21 0,000 0,04928557 0,07014654 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04928557 0,07010316 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,04928557 0,07005984 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,04928557 0,07001656 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04928557 0,06997334 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04928557 0,06993018 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04928557 0,06988706 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04928557 0,069844 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04928557 0,06980099 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04928557 0,06975804 ! fatty acid transport GO:0015908 30 21 0,000 0,04928557 0,06971514 ! immunoglobulin production GO:0002377 33 21 0,000 0,04928557 0,06967229 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04928557 0,06962949 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,04928557 0,06958675 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04928557 0,06954406 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04928557 0,06950142 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04928557 0,06945883 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04928557 0,0694163 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04928557 0,06937382 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04928557 0,06933138 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04928557 0,06928901 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04928557 0,06924668 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04928557 0,0692044 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04928557 0,06916218 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04928557 0,06912001 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04928557 0,06907789 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,05157238 0,07223902 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,05157238 0,07219506 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,05157238 0,07215114 ! viral genome replication GO:0019079 29 22 0,000 0,05157238 0,07210728 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,05157238 0,07206347 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,05157238 0,07201972 ! leukocyte adhesion GO:0007159 38 22 0,000 0,05157238 0,07197602 ! molting cycle process GO:0022404 40 22 0,000 0,05157238 0,07193237 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,05157238 0,07188878 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,05157238 0,07184523 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,05157238 0,07180174 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,05157238 0,07175831 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,05157238 0,07171492 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,05157238 0,07167159 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,05157238 0,07162831 ! lysosome organization GO:0007040 37 22 0,000 0,05157238 0,07158508 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,05157238 0,07154191 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,05157238 0,07149878 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,05157238 0,07145571 ! regulation of behavior GO:0050795 38 22 0,000 0,05157238 0,07141269 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,05157238 0,07136972 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,05157238 0,07132681 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,05157238 0,07128394 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,05157238 0,07124113 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,05157238 0,07119837 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,05157238 0,07115566 ! blastocyst development GO:0001824 37 22 0,000 0,05157238 0,071113 ! neural tube closure GO:0001843 33 22 0,000 0,05157238 0,07107039 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 0,000 0,05157238 0,07102783 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,05385382 0,07412555 ! neuron fate commitment GO:0048663 32 23 0,000 0,05385382 0,07408122 ! embryonic pattern specification GO:0009880 31 23 0,000 0,05385382 0,07403694 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,05385382 0,07399271 ! myelination GO:0042552 35 23 0,000 0,05385382 0,07394853 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,05385382 0,07390441 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,05385382 0,07386034 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,05385382 0,07381632 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,05385382 0,07377236 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,05385382 0,07372845 ! vesicle targeting GO:0006903 32 23 0,000 0,05385382 0,07368459 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,05385382 0,07364078 ! osteoblast differentiation GO:0001649 40 23 0,000 0,05385382 0,07359703 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,05385382 0,07355332 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,05385382 0,07350967 ! interaction with host GO:0051701 37 23 0,000 0,05385382 0,07346607 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,05385382 0,07342252 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,05385382 0,07337902 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,05385382 0,07333558 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,05385382 0,07329219 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,05385382 0,07324884 ! cell fate determination GO:0001709 45 23 0,000 0,05385382 0,07320555 ! pentose metabolic process GO:0019321 31 23 0,000 0,05385382 0,07316231 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,05385382 0,07311912 ! spermatid development GO:0007286 33 23 0,000 0,05385382 0,07307598 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,05385382 0,0730329 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,05385382 0,07298986 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,05385382 0,07294687 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,05385382 0,07290394 ! telomere organization GO:0032200 32 23 0,000 0,05385382 0,07286105 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,05385382 0,07281822 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,05385382 0,07277544 ! regulation of amine transport GO:0051952 38 23 0,000 0,05385382 0,0727327 ! liver development GO:0001889 40 23 0,000 0,05385382 0,07269002 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,05612991 0,07571776 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,05612991 0,07567338 ! initiation of viral infection GO:0019059 42 24 0,000 0,05612991 0,07562905 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,05612991 0,07558477 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,05612991 0,07554054 ! superoxide metabolic process GO:0006801 32 24 0,000 0,05612991 0,07549637 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,05612991 0,07545224 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,05612991 0,07540817 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,05612991 0,07536415 ! sperm motility GO:0030317 27 24 0,000 0,05612991 0,07532018 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,05612991 0,07527626 ! vacuole organization GO:0007033 39 24 0,000 0,05612991 0,07523239 ! receptor metabolic process GO:0043112 37 24 0,000 0,05612991 0,07518858 ! neural crest cell development GO:0014032 39 24 0,000 0,05612991 0,07514481 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,05612991 0,0751011 ! primary neural tube formation GO:0014020 35 24 0,000 0,05612991 0,07505743 ! negative regulation of cell development GO:0010721 56 24 0,000 0,05612991 0,07501382 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,05612991 0,07497026 ! base-excision repair GO:0006284 31 24 0,000 0,05612991 0,07492675 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,05612991 0,07488329 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,05612991 0,07483988 ! glutathione metabolic process GO:0006749 29 24 0,000 0,05612991 0,07479652 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,05612991 0,07475321 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,05612991 0,07470995 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,05840064 0,07768738 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,05840064 0,07764248 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,05840064 0,07759762 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,05840064 0,07755282 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,05840064 0,07750807 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,05840064 0,07746337 ! peptide transport GO:0015833 43 25 0,000 0,05840064 0,07741872 ! male gonad development GO:0008584 33 25 0,000 0,05840064 0,07737413 ! iron ion homeostasis GO:0055072 39 25 0,000 0,05840064 0,07732958 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,05840064 0,07728509 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,05840064 0,07724065 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,05840064 0,07719625 ! phospholipid transport GO:0015914 35 25 0,000 0,05840064 0,07715191 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,05840064 0,07710762 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,05840064 0,07706339 ! detection of light stimulus GO:0009583 30 25 0,000 0,05840064 0,0770192 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,05840064 0,07697506 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,05840064 0,07693098 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,05840064 0,07688694 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,06066605 0,07982375 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,06066605 0,07977811 ! translational initiation GO:0006413 43 26 0,000 0,06066605 0,07973252 ! regulation of pH GO:0006885 36 26 0,000 0,06066605 0,07968699 ! circadian rhythm GO:0007623 42 26 0,000 0,06066605 0,0796415 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,06066605 0,07959607 ! post-embryonic development GO:0009791 42 26 0,000 0,06066605 0,07955069 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,06066605 0,07950536 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,06066605 0,07946009 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,06066605 0,07941486 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,06066605 0,07936969 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,06066605 0,07932457 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,06292613 0,08223302 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,06292613 0,08218632 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,06292613 0,08213967 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,06292613 0,08209308 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,06292613 0,08204655 ! catechol metabolic process GO:0009712 43 27 0,000 0,06292613 0,08200006 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,06292613 0,08195363 ! acute-phase response GO:0006953 42 27 0,000 0,06292613 0,08190725 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,06292613 0,08186092 ! myofibril assembly GO:0030239 36 27 0,000 0,06292613 0,08181464 GO:0055002|striated muscle cell development, ! response to ionizing radiation GO:0010212 47 27 0,000 0,06292613 0,08176842 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,06292613 0,08172225 ! natural killer cell activation GO:0030101 35 27 0,000 0,06292613 0,08167613 ! lipid oxidation GO:0034440 38 27 0,000 0,06292613 0,08163007 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,06292613 0,08158405 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,06292613 0,08153809 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,06292613 0,08149218 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,06292613 0,08144632 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,06292613 0,08140051 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,06292613 0,08135475 ! gene silencing GO:0016458 41 27 0,000 0,06292613 0,08130905 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,06518091 0,08417523 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,06518091 0,084128 ! phenol metabolic process GO:0018958 44 28 0,000 0,06518091 0,08408081 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,06518091 0,08403368 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,06518091 0,08398661 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,06518091 0,08393958 ! cell junction assembly GO:0034329 56 28 0,000 0,06518091 0,08389261 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,06518091 0,08384569 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,06518091 0,08379882 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,06518091 0,08375201 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,06518091 0,08370524 ! response to organic cyclic substance GO:0014070 47 28 0,000 0,06518091 0,08365853 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,06518091 0,08361187 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,06518091 0,08356527 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,06518091 0,08351871 ! mesoderm formation GO:0001707 46 28 0,000 0,06518091 0,08347221 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,06518091 0,08342576 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,06518091 0,08337936 ! ensheathment of neurons GO:0007272 43 28 0,000 0,06518091 0,08333301 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,06518091 0,08328672 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,06518091 0,08324047 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,06518091 0,08319428 ! neural tube formation GO:0001841 41 28 0,000 0,06518091 0,08314814 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,06518091 0,08310205 ! placenta development GO:0001890 37 28 0,000 0,06518091 0,08305601 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,06743039 0,0858748 ! regulation of innate immune response GO:0045088 38 29 0,000 0,06743039 0,08582728 ! ovulation cycle process GO:0022602 41 29 0,000 0,06743039 0,08577981 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,06743039 0,08573239 ! protein targeting to membrane GO:0006612 53 29 0,000 0,06743039 0,08568502 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,06743039 0,08563771 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,06743039 0,08559045 ! muscle cell development GO:0055001 38 29 0,000 0,06743039 0,08554324 ! formation of primary germ layer GO:0001704 48 29 0,000 0,06743039 0,08549608 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,06743039 0,08544898 ! eye morphogenesis GO:0048592 51 29 0,000 0,06743039 0,08540192 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,06743039 0,08535492 ! tissue homeostasis GO:0001894 42 29 0,000 0,06743039 0,08530797 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,06967458 0,0880987 ! collagen metabolic process GO:0032963 40 30 0,000 0,06967458 0,0880503 ! organic anion transport GO:0015711 51 30 0,000 0,06967458 0,08800194 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,06967458 0,08795364 ! spliceosome assembly GO:0000245 49 30 0,000 0,06967458 0,0879054 ! spindle organization GO:0007051 37 30 0,000 0,06967458 0,0878572 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,06967458 0,08780906 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,06967458 0,08776097 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,06967458 0,08771294 ! ceramide metabolic process GO:0006672 43 30 0,000 0,06967458 0,08766496 ! ovulation cycle GO:0042698 43 30 0,000 0,06967458 0,08761702 ! hindbrain development GO:0030902 45 30 0,000 0,06967458 0,08756915 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,06967458 0,08752132 ! adult locomotory behavior GO:0008344 47 30 0,000 0,06967458 0,08747355 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,06967458 0,08742583 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,06967458 0,08737816 ! response to heat GO:0009408 41 30 0,000 0,06967458 0,08733054 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,06967458 0,08728297 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,06967458 0,08723546 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,0719135 0,08998969 ! negative regulation of secretion GO:0051048 49 31 0,000 0,0719135 0,08994076 ! glial cell differentiation GO:0010001 55 31 0,000 0,0719135 0,08989188 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,0719135 0,08984305 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,0719135 0,08979428 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,0719135 0,08974556 ! odontogenesis GO:0042476 50 31 0,000 0,0719135 0,08969689 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,0719135 0,08964827 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,0719135 0,08959971 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,0719135 0,0895512 ! metanephros development GO:0001656 58 31 0,000 0,0719135 0,08950274 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,0719135 0,08945433 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,0719135 0,08940598 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,0719135 0,08935768 ! cell fate specification GO:0001708 37 31 0,000 0,0719135 0,08930943 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,0719135 0,08926123 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,0719135 0,08921308 ! RNA modification GO:0009451 40 31 0,000 0,0719135 0,08916499 ! regulation of muscle development GO:0048634 48 32 0,000 0,07414717 0,09188496 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,07414717 0,09183548 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,07414717 0,09178605 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,07414717 0,09173668 ! meiosis I GO:0007127 52 32 0,000 0,07414717 0,09168736 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,07414717 0,09163809 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,07414717 0,09158887 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,07414717 0,09153971 ! peripheral nervous system development GO:0007422 53 32 0,000 0,07414717 0,0914906 ! regulation of protein stability GO:0031647 48 32 0,000 0,07414717 0,09144154 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,07414717 0,09139254 ! cytokine production GO:0001816 44 32 0,000 0,07414717 0,09134359 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,07414717 0,09129469 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,07414717 0,09124584 ! vesicle localization GO:0051648 47 32 0,000 0,07414717 0,09119705 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,07637558 0,09388767 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,07637558 0,09383752 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,07637558 0,09378742 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,07637558 0,09373737 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,07637558 0,09368738 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,07637558 0,09363744 ! sister chromatid segregation GO:0000819 46 33 0,000 0,07637558 0,09358755 ! ear morphogenesis GO:0042471 42 33 0,000 0,07637558 0,09353772 ! actomyosin structure organization GO:0031032 43 33 0,000 0,07637558 0,09348794 ! cell junction organization GO:0034330 63 33 0,000 0,07637558 0,09343821 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,07637558 0,09338853 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,07637558 0,09333891 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,07637558 0,09328934 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,07637558 0,09323983 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,07637558 0,09319036 ! female gonad development GO:0008585 49 33 0,000 0,07637558 0,09314095 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,07637558 0,09309159 ! positive regulation of cell development GO:0010720 54 33 0,000 0,07637558 0,09304228 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,07637558 0,09299303 ! regulation of proteolysis GO:0030162 50 33 0,000 0,07637558 0,09294383 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,07637558 0,09289468 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,07637558 0,09284558 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,07637558 0,09279653 ! cytokinesis GO:0000910 52 33 0,000 0,07637558 0,09274754 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,07637558 0,09269859 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,07859876 0,09534659 ! mRNA catabolic process GO:0006402 48 34 0,000 0,07859876 0,09529633 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,07859876 0,09524612 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,07859876 0,09519597 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,07859876 0,09514586 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,07859876 0,09509581 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,07859876 0,09504582 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,07859876 0,09499587 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,07859876 0,09494598 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,07859876 0,09489614 ! female gamete generation GO:0007292 43 34 0,000 0,07859876 0,09484635 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,07859876 0,09479661 ! polyol metabolic process GO:0019751 44 34 0,000 0,07859876 0,09474693 ! aerobic respiration GO:0009060 47 34 0,000 0,07859876 0,0946973 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,07859876 0,09464772 ! embryonic organ development GO:0048568 45 34 0,000 0,07859876 0,09459819 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,07859876 0,09454871 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,08081671 0,09716594 ! Notch signaling pathway GO:0007219 56 35 0,000 0,08081671 0,09711517 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,08081671 0,09706446 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,08081671 0,0970138 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,08081671 0,09696319 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,08081671 0,09691263 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,08081671 0,09686213 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,08081671 0,09681168 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,08081671 0,09676129 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,08081671 0,09671094 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,08081671 0,09666065 ! glycogen metabolic process GO:0005977 48 35 0,000 0,08081671 0,09661041 ! pigment metabolic process GO:0042440 61 35 0,000 0,08081671 0,09656023 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,08302945 0,09915251 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,08302945 0,09910106 ! negative regulation of binding GO:0051100 58 36 0,000 0,08302945 0,09904966 ! neural tube development GO:0021915 50 36 0,000 0,08302945 0,09899831 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,08302945 0,09894702 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,08302945 0,09889577 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,08302945 0,09884459 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,08302945 0,09879345 ! glucan metabolic process GO:0044042 49 36 0,000 0,08302945 0,09874237 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,08523699 0,10131529 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,08523699 0,10126296 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,08523699 0,10121068 ! ion transmembrane transport GO:0034220 56 37 0,000 0,08523699 0,10115845 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,08523699 0,10110628 ! regulation of protein secretion GO:0050708 51 37 0,000 0,08523699 0,10105417 ! amino acid activation GO:0043038 52 37 0,000 0,08523699 0,1010021 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,08523699 0,10095009 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,08743935 0,10350514 ! gliogenesis GO:0042063 71 38 0,000 0,08743935 0,1034519 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,08743935 0,10339871 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,08743935 0,10334558 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,08743935 0,1032925 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,08743935 0,10323947 ! phagocytosis GO:0006909 60 38 0,000 0,08743935 0,1031865 ! mesenchymal cell development GO:0014031 64 38 0,000 0,08743935 0,10313359 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,08743935 0,10308073 ! maintenance of location in cell GO:0051651 69 38 0,000 0,08743935 0,10302792 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,08963652 0,10556272 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,08963652 0,1055087 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,08963652 0,10545473 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,08963652 0,10540082 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,08963652 0,10534696 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,08963652 0,10529316 ! male sex differentiation GO:0046661 53 39 0,000 0,08963652 0,10523941 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,08963652 0,10518571 ! chromatin remodeling GO:0006338 68 39 0,000 0,08963652 0,10513208 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,08963652 0,10507849 ! developmental growth GO:0048589 62 39 0,000 0,08963652 0,10502496 ! cell growth GO:0016049 61 39 0,000 0,08963652 0,10497149 ! synapse organization GO:0050808 55 39 0,000 0,08963652 0,10491807 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,09182853 0,10742911 ! response to calcium ion GO:0051592 58 40 0,000 0,09182853 0,10737449 ! regulation of tube size GO:0035150 60 40 0,000 0,09182853 0,10731993 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,09182853 0,10726543 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,09182853 0,10721098 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,09182853 0,10715658 ! peptide metabolic process GO:0006518 56 40 0,000 0,09182853 0,10710225 ! inner ear development GO:0048839 57 40 0,000 0,09182853 0,10704796 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,09182853 0,10699373 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,09182853 0,10693956 ! double-strand break repair GO:0006302 67 40 0,000 0,09182853 0,10688544 ! B cell differentiation GO:0030183 62 40 0,000 0,09182853 0,10683138 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,09182853 0,10677737 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,09182853 0,10672341 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,09182853 0,10666951 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,09182853 0,10661566 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,09401539 0,1090996 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,09401539 0,10904458 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,09401539 0,10898962 ! glucose transport GO:0015758 52 41 0,000 0,09401539 0,10893471 ! endosome transport GO:0016197 71 41 0,000 0,09401539 0,10887986 ! striated muscle contraction GO:0006941 62 41 0,000 0,09401539 0,10882507 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,09401539 0,10877032 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,09401539 0,10871564 ! biopolymer methylation GO:0043414 62 41 0,000 0,09401539 0,10866101 ! mitochondrial transport GO:0006839 60 42 0,000 0,09619711 0,11112675 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,09619711 0,11107096 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,09619711 0,11101523 ! cellular component disassembly GO:0022411 64 42 0,000 0,09619711 0,11095956 ! hexose transport GO:0008645 54 42 0,000 0,09619711 0,11090394 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,09619711 0,11084838 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,09619711 0,11079287 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,09619711 0,11073742 ! excretion GO:0007588 63 42 0,000 0,09619711 0,11068202 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,09619711 0,11062668 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,09619711 0,11057139 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,09619711 0,11051616 ! regulation of cell shape GO:0008360 78 42 0,000 0,09619711 0,11046099 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,0983737 0,11290395 ! leukocyte migration GO:0050900 60 43 0,000 0,0983737 0,11284764 ! neuromuscular process GO:0050905 79 43 0,000 0,0983737 0,11279138 ! activation of caspase activity GO:0006919 65 43 0,000 0,0983737 0,11273518 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,0983737 0,11267904 ! tRNA processing GO:0008033 49 43 0,000 0,0983737 0,11262295 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,0983737 0,11256692 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,0983737 0,11251095 ! methylation GO:0032259 64 43 0,000 0,0983737 0,11245503 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,10054517 0,11488023 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,10054517 0,11482319 ! glycolysis GO:0006096 53 44 0,000 0,10054517 0,1147662 ! regulation of action potential GO:0001508 71 44 0,000 0,10054517 0,11470928 ! regulation of ion transport GO:0043269 57 44 0,000 0,10054517 0,1146524 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,10054517 0,11459559 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,10054517 0,11453883 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,10054517 0,11448213 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,10054517 0,11442548 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,10054517 0,11436889 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,10054517 0,11431236 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,10054517 0,11425588 ! RNA catabolic process GO:0006401 64 45 0,000 0,10271154 0,11666002 ! positive regulation of defense response GO:0031349 59 45 0,000 0,10271154 0,11660244 ! regulation of translational initiation GO:0006446 64 45 0,000 0,10271154 0,11654492 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,10271154 0,11648745 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,10271154 0,11643004 ! cell recognition GO:0008037 58 45 0,000 0,10271154 0,11637268 ! cell maturation GO:0048469 60 45 0,000 0,10271154 0,11631538 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,10487281 0,11870446 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,10487281 0,11864608 ! cell redox homeostasis GO:0045454 63 46 0,000 0,10487281 0,11858774 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,10487281 0,11852947 ! regulation of ossification GO:0030278 71 46 0,000 0,10487281 0,11847125 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,10487281 0,11841309 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,107029 0,12078838 ! viral infectious cycle GO:0019058 71 47 0,000 0,107029 0,12072914 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,107029 0,12066996 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,107029 0,12061083 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,107029 0,12055177 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,107029 0,12049276 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,107029 0,12043381 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,107029 0,12037492 ! chloride transport GO:0006821 67 48 0,000 0,10918012 0,12273426 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,10918012 0,1226743 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,10918012 0,1226144 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,10918012 0,12255456 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,10918012 0,12249477 ! gastrulation GO:0007369 73 48 0,000 0,10918012 0,12243505 ! heart morphogenesis GO:0003007 65 48 0,000 0,10918012 0,12237538 ! regulation of DNA replication GO:0006275 75 48 0,000 0,10918012 0,12231578 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,10918012 0,12225623 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,10918012 0,12219673 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,10918012 0,1221373 ! regulation of endocytosis GO:0030100 63 48 0,000 0,10918012 0,12207792 ! nuclear export GO:0051168 69 48 0,000 0,10918012 0,1220186 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,10918012 0,12195934 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,10918012 0,12190014 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,11132619 0,12423592 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,11132619 0,12417567 ! sensory perception of smell GO:0007608 61 49 0,000 0,11132619 0,12411548 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,11132619 0,12405534 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,11132619 0,12399527 ! RNA elongation GO:0006354 62 49 0,000 0,11132619 0,12393525 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,11132619 0,12387529 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,11132619 0,12381539 ! germ cell development GO:0007281 68 49 0,000 0,11132619 0,12375555 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,11132619 0,12369576 ! cartilage development GO:0051216 70 49 0,000 0,11132619 0,12363603 ! maintenance of location GO:0051235 84 49 0,000 0,11132619 0,12357636 ! regulation of actin filament length GO:0030832 72 50 0,000 0,1134672 0,12589221 ! ear development GO:0043583 72 50 0,000 0,1134672 0,12583151 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,1134672 0,12577087 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,1134672 0,12571029 ! positive regulation of growth GO:0045927 67 50 0,000 0,1134672 0,12564976 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,1134672 0,1255893 ! proton transport GO:0015992 75 50 0,000 0,1134672 0,12552889 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,1134672 0,12546854 ! positive regulation of secretion GO:0051047 71 51 0,000 0,11560318 0,12776901 ! hydrogen transport GO:0006818 77 51 0,000 0,11560318 0,12770764 ! muscle fiber development GO:0048747 74 51 0,000 0,11560318 0,12764633 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,11560318 0,12758508 ! adult behavior GO:0030534 80 51 0,000 0,11560318 0,12752389 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,11560318 0,12746276 ! transition metal ion transport GO:0000041 74 52 0,000 0,11773413 0,12975012 ! regulation of cellular component size GO:0032535 74 52 0,000 0,11773413 0,12968798 ! aging GO:0007568 79 52 0,000 0,11773413 0,1296259 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,11773413 0,12956388 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,11773413 0,12950192 ! establishment of organelle localization GO:0051656 85 52 0,000 0,11773413 0,12944001 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,11986008 0,13171437 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,11986008 0,13165147 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,11986008 0,13158863 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,11986008 0,13152585 ! kidney development GO:0001822 90 53 0,000 0,11986008 0,13146312 ! single fertilization GO:0007338 59 53 0,000 0,11986008 0,13140046 ! cell projection assembly GO:0030031 76 53 0,000 0,11986008 0,13133786 ! amino acid transport GO:0006865 84 54 0,000 0,12198102 0,13359826 ! regulation of mitosis GO:0007088 84 54 0,000 0,12198102 0,13353467 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,12198102 0,13347114 ! DNA catabolic process GO:0006308 67 54 0,000 0,12198102 0,13340767 ! detection of external stimulus GO:0009581 66 54 0,000 0,12198102 0,13334427 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,12198102 0,13328092 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,12198102 0,13321763 ! exocytosis GO:0006887 74 55 0,000 0,12409697 0,13546418 ! mesoderm development GO:0007498 76 55 0,000 0,12409697 0,13539992 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,12409697 0,13533572 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,12409697 0,13527158 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,12620794 0,13750747 ! carbohydrate transport GO:0008643 74 57 0,000 0,12831395 0,13973583 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,12831395 0,1396697 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,12831395 0,13960363 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,12831395 0,13953762 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,12831395 0,13947168 ! camera-type eye development GO:0043010 88 57 0,000 0,12831395 0,1394058 ! secondary metabolic process GO:0019748 84 57 0,000 0,12831395 0,13933998 ! developmental maturation GO:0021700 75 57 0,000 0,12831395 0,13927422 ! gonad development GO:0008406 79 57 0,000 0,12831395 0,13920853 ! viral reproductive process GO:0022415 87 58 0,000 0,130415 0,14142126 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,130415 0,14135462 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,130415 0,14128803 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,130415 0,14122151 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,1325111 0,14342378 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,1325111 0,14335632 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,1325111 0,14328892 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,13460228 0,14548179 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,13460228 0,14541345 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,13460228 0,14534518 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,13460228 0,14527698 ! regulation of heart contraction GO:0008016 91 60 0,000 0,13460228 0,14520884 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,13460228 0,14514076 ! fertilization GO:0009566 68 60 0,000 0,13460228 0,14507275 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,13460228 0,1450048 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,13668853 0,14718334 ! urogenital system development GO:0001655 101 61 0,000 0,13668853 0,14711447 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,13668853 0,14704566 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,13668853 0,14697692 ! extracellular matrix organization GO:0030198 103 61 0,000 0,13668853 0,14690824 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,13668853 0,14683962 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,13668853 0,14677107 ! amine catabolic process GO:0009310 90 62 0,000 0,13876988 0,1489364 ! neurotransmitter transport GO:0006836 81 62 0,000 0,13876988 0,14886694 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,13876988 0,14879754 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,13876988 0,1487282 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,13876988 0,14865893 ! organelle localization GO:0051640 96 62 0,000 0,13876988 0,14858972 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,14084632 0,15074292 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,14084632 0,15067281 ! viral reproduction GO:0016032 92 63 0,000 0,14084632 0,15060276 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,14291788 0,1527468 ! appendage morphogenesis GO:0035107 93 64 0,000 0,14291788 0,15267586 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,14291788 0,15260498 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,14291788 0,15253416 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,14291788 0,15246341 ! hexose catabolic process GO:0019320 82 64 0,000 0,14291788 0,15239273 ! adaptive immune response GO:0002250 94 64 0,000 0,14291788 0,15232211 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,14498456 0,15445321 ! regulation of caspase activity GO:0043281 97 65 0,000 0,14498456 0,15438171 ! appendage development GO:0048736 94 65 0,000 0,14498456 0,15431027 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,14498456 0,15423889 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,14498456 0,15416758 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,14498456 0,15409634 ! defense response to bacterium GO:0042742 73 65 0,000 0,14498456 0,15402517 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,14498456 0,15395406 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,14704637 0,15607137 ! antigen processing and presentation GO:0019882 96 66 0,000 0,14704637 0,15599938 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,14704637 0,15592746 ! regulation of immune effector process GO:0002697 101 66 0,000 0,14704637 0,1558556 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,14910334 0,157963 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,14910334 0,15789027 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,14910334 0,15781761 ! acute inflammatory response GO:0002526 92 68 0,000 0,15115546 0,15991608 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,15115546 0,15984255 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,15115546 0,15976909 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,15115546 0,1596957 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,15115546 0,15962238 ! rhythmic process GO:0048511 105 68 0,000 0,15115546 0,15954913 ! inorganic anion transport GO:0015698 93 68 0,000 0,15115546 0,15947594 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,15320274 0,16156181 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,15320274 0,16148777 ! response to drug GO:0042493 108 69 0,000 0,15320274 0,16141379 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,15320274 0,16133989 ! response to metal ion GO:0010038 103 70 0,000 0,15524521 0,16341601 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,15524521 0,16334126 ! humoral immune response GO:0006959 86 70 0,000 0,15524521 0,16326657 ! eye development GO:0001654 111 70 0,000 0,15524521 0,16319195 ! amine transport GO:0015837 101 70 0,000 0,15524521 0,1631174 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,15524521 0,16304292 ! regulation of catabolic process GO:0009894 106 70 0,000 0,15524521 0,1629685 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,15728287 0,16503221 ! muscle cell differentiation GO:0042692 104 71 0,000 0,15728287 0,16495695 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,15728287 0,16488177 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,15728287 0,16480665 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,15728287 0,1647316 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,15728287 0,16465662 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,15728287 0,16458171 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,15931573 0,1666331 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,15931573 0,16655735 ! negative regulation of transport GO:0051051 116 73 0,000 0,1613438 0,16860097 ! regulation of blood pressure GO:0008217 107 73 0,000 0,1613438 0,16852441 ! tube morphogenesis GO:0035239 118 73 0,000 0,1613438 0,16844791 ! mitochondrion organization GO:0007005 104 73 0,000 0,1613438 0,16837148 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,1613438 0,16829512 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,1613438 0,16821883 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,1633671 0,17025117 ! digestion GO:0007586 97 74 0,000 0,1633671 0,17017406 ! protein import into nucleus GO:0006606 118 74 0,000 0,1633671 0,17009702 ! blood coagulation GO:0007596 116 75 0,000 0,16538563 0,17212079 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,16538563 0,17204294 ! response to nutrient GO:0007584 104 75 0,000 0,16538563 0,17196516 ! regulation of ligase activity GO:0051340 114 75 0,000 0,16538563 0,17188746 ! nuclear import GO:0051170 121 75 0,000 0,16538563 0,17180982 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,16538563 0,17173225 ! amine biosynthetic process GO:0009309 97 76 0,000 0,1673994 0,17374487 ! tRNA metabolic process GO:0006399 95 76 0,000 0,1673994 0,1736665 ! response to unfolded protein GO:0006986 99 76 0,000 0,1673994 0,1735882 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,1673994 0,17350997 ! regulation of protein transport GO:0051223 114 76 0,000 0,1673994 0,17343182 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,16940844 0,17543422 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,16940844 0,17535527 ! sex differentiation GO:0007548 105 77 0,000 0,16940844 0,17527639 ! protein ubiquitination GO:0016567 125 77 0,000 0,16940844 0,17519757 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,16940844 0,17511883 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,16940844 0,17504016 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,16940844 0,17496156 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,17141274 0,17695211 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,17141274 0,17687272 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,17141274 0,17679341 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,17341232 0,17877558 ! cellular respiration GO:0045333 107 79 0,000 0,17341232 0,17869549 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,17341232 0,17861546 ! T cell activation GO:0042110 134 79 0,000 0,17341232 0,17853551 ! regulation of lyase activity GO:0051339 133 79 0,000 0,17341232 0,17845563 ! chromatin assembly GO:0031497 102 80 0,000 0,17540718 0,18042778 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,17540718 0,18034713 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,17540718 0,18026654 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,17540718 0,18018603 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,17540718 0,18010559 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,17739735 0,18206779 ! hemostasis GO:0007599 125 81 0,000 0,17739735 0,18198658 ! mRNA transport GO:0051028 121 81 0,000 0,17739735 0,18190544 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,17739735 0,18182438 ! response to protein stimulus GO:0051789 111 81 0,000 0,17739735 0,18174339 ! regulation of neurological system process GO:0031644 122 81 0,000 0,17739735 0,18166247 ! vitamin metabolic process GO:0006766 103 81 0,000 0,17739735 0,18158162 ! detection of stimulus GO:0051606 108 82 0,000 0,17938283 0,18353225 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,18136363 0,18547637 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,18136363 0,18539393 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,18136363 0,18531157 ! regulation of defense response GO:0031347 117 84 0,000 0,18333976 0,18724754 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,18333976 0,18716443 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,18333976 0,18708139 ! sterol metabolic process GO:0016125 120 84 0,000 0,18333976 0,18699843 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,18531124 0,18892546 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,18531124 0,18884176 ! rRNA metabolic process GO:0016072 107 85 0,000 0,18531124 0,18875813 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,18531124 0,18867457 ! regulation of protein localization GO:0032880 132 85 0,000 0,18531124 0,18859108 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,18727807 0,19050843 ! nucleosome organization GO:0034728 114 87 0,000 0,18924026 0,19241936 ! cellular defense response GO:0006968 102 87 0,000 0,18924026 0,19233433 ! female pregnancy GO:0007565 130 87 0,000 0,18924026 0,19224938 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,18924026 0,1921645 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,19119783 0,19406664 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,19119783 0,19398104 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,19119783 0,19389551 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,19119783 0,19381005 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,19315078 0,19570344 ! reproductive developmental process GO:0003006 127 89 0,000 0,19315078 0,19561726 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,19315078 0,19553116 ! regulation of T cell activation GO:0050863 128 89 0,000 0,19315078 0,19544514 ! leukocyte differentiation GO:0002521 143 90 0,000 0,19509913 0,19732982 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,19509913 0,19724308 ! hormone metabolic process GO:0042445 121 90 0,000 0,19509913 0,19715642 ! RNA localization GO:0006403 135 91 0,000 0,19704289 0,19903322 ! response to virus GO:0009615 122 91 0,000 0,19704289 0,19894585 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,19898207 0,2008156 ! cell fate commitment GO:0045165 141 92 0,000 0,19898207 0,20072752 ! DNA recombination GO:0006310 146 92 0,000 0,19898207 0,20063952 ! sulfur metabolic process GO:0006790 118 92 0,000 0,19898207 0,2005516 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,20091667 0,20241277 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,20091667 0,20232414 ! electron transport chain GO:0022900 123 94 0,000 0,20284671 0,20417831 ! angiogenesis GO:0001525 149 95 0,000 0,2047722 0,20602628 ! carboxylic acid transport GO:0046942 147 95 0,000 0,2047722 0,20593619 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,20669315 0,20777721 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,20669315 0,20768644 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,20669315 0,20759575 ! protein maturation GO:0051604 129 96 0,000 0,20669315 0,20750513 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,20860958 0,20933771 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,20860958 0,20924641 ! extracellular structure organization GO:0043062 156 99 0,000 0,21242887 0,21298448 ! protein import GO:0017038 156 99 0,000 0,21242887 0,21289168 ! regulation of translation GO:0006417 151 100 0,000 0,21433176 0,21470516 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,21433176 0,21461169 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,21433176 0,2145183 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,21433176 0,21442499 ! protein localization in organelle GO:0033365 161 100 0,000 0,21433176 0,21433176