pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1308-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 4,939E-09 1,188E-05 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 2,000 2,191E-07 2,636E-04 ! establishment of spindle localization GO:0051293 12 6 2,000 2,191E-07 1,757E-04 GO:0051653|spindle localization, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 2,9E-07 1,745E-04 ! platelet activating factor metabolic process GO:0046469 11 7 2,000 3,828E-07 1,842E-04 ! cerebral cortex cell migration GO:0021795 15 9 2,000 9,158E-07 3,672E-04 ! central nervous system neuron axonogenesis GO:0021955 22 10 2,000 1,306E-06 4,489E-04 GO:0021952|central nervous system projection neuron axonogenesis, ! brain morphogenesis GO:0048854 23 10 2,000 1,306E-06 3,928E-04 ! androgen receptor signaling pathway GO:0030521 74 36 3,000 1,326E-06 3,544E-04 ! telencephalon cell migration GO:0022029 20 11 2,000 1,793E-06 4,314E-04 ! neuroblast proliferation GO:0007405 24 11 2,000 1,793E-06 3,922E-04 ! hippocampus development GO:0021766 26 12 2,000 2,387E-06 4,786E-04 ! forebrain cell migration GO:0021885 21 12 2,000 2,387E-06 4,418E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 4,913E-06 8,443E-04 ! axon cargo transport GO:0008088 43 16 2,000 6,036E-06 9,682E-04 ! limbic system development GO:0021761 36 17 2,000 7,318E-06 1,1E-03 ! cerebral cortex development GO:0021987 36 19 2,000 1,039E-05 1,471E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,221E-05 1,632E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 1,28E-05 1,621E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 2,000 1,422E-05 1,711E-03 ! microtubule-based transport GO:0010970 54 22 2,000 1,644E-05 1,884E-03 ! central nervous system neuron development GO:0021954 46 22 2,000 1,644E-05 1,798E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,644E-05 1,72E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 1,736E-05 1,74E-03 ! central nervous system neuron differentiation GO:0021953 50 24 2,000 2,154E-05 2,073E-03 ! pallium development GO:0021543 49 24 2,000 2,154E-05 1,993E-03 ! neuromuscular process controlling balance GO:0050885 60 25 2,000 2,443E-05 2,177E-03 ! ethanolamine and derivative metabolic process GO:0042439 46 28 2,000 3,463E-05 2,976E-03 ! response to superoxide GO:0000303 10 5 1,000 5,001E-05 4,149E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 5,001E-05 4,011E-03 ! adult locomotory behavior GO:0008344 59 33 2,000 5,722E-05 4,441E-03 ! spermatid development GO:0007286 63 34 2,000 6,265E-05 4,711E-03 ! telencephalon development GO:0021537 68 35 2,000 6,842E-05 4,988E-03 ! response to oxygen radical GO:0000305 11 6 1,000 7,491E-05 5,301E-03 ! malate metabolic process GO:0006108 11 6 1,000 7,491E-05 5,149E-03 ! removal of superoxide radicals GO:0019430 11 6 1,000 7,491E-05 5,006E-03 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 2,000 8,096E-05 5,265E-03 ! spermatid differentiation GO:0048515 66 37 2,000 8,096E-05 5,126E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 1,024E-04 6,32E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,047E-04 6,299E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,047E-04 6,145E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 1,047E-04 5,999E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 1,047E-04 5,859E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 1,047E-04 5,726E-03 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 2,000 1,187E-04 6,344E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,187E-04 6,206E-03 ! neuron migration GO:0001764 79 42 2,000 1,187E-04 6,074E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,394E-04 6,988E-03 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 1,000 1,394E-04 6,846E-03 ! ER overload response GO:0006983 12 8 1,000 1,394E-04 6,709E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,394E-04 6,577E-03 ! glycolysis GO:0006096 65 45 2,000 1,46E-04 6,753E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,559E-04 7,077E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,559E-04 6,946E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 1,79E-04 7,83E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,79E-04 7,69E-03 ! gas homeostasis GO:0033483 16 9 1,000 1,79E-04 7,555E-03 ! induction of an organ GO:0001759 14 9 1,000 1,79E-04 7,425E-03 ! neuromuscular process GO:0050905 99 50 2,000 2E-04 8,155E-03 ! negative regulation of blood pressure GO:0045776 26 10 1,000 2,234E-04 8,959E-03 ! localization within membrane GO:0051668 20 10 1,000 2,234E-04 8,812E-03 ! glucose catabolic process GO:0006007 82 55 2,000 2,655E-04 0,01030408 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,727E-04 0,01041313 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,727E-04 0,01025042 ! developmental induction GO:0031128 19 11 1,000 2,727E-04 0,01009272 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of intracellular transport GO:0032386 101 57 2,000 2,952E-04 0,01076091 ! adult behavior GO:0030534 99 58 2,000 3,108E-04 0,01116048 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 3,267E-04 0,01156006 ! mitotic spindle organization GO:0007052 21 12 1,000 3,267E-04 0,01139252 ! histone acetylation GO:0016573 26 12 1,000 3,267E-04 0,01122977 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,267E-04 0,0110716 ! establishment of organelle localization GO:0051656 109 59 2,000 3,269E-04 0,01092418 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,856E-04 0,01270757 ! germ cell development GO:0007281 118 65 2,000 4,35E-04 0,01414384 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,492E-04 0,01440911 ! response to gamma radiation GO:0010332 28 14 1,000 4,492E-04 0,01421952 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 4,492E-04 0,01403485 ! lung development GO:0030324 144 67 2,000 4,756E-04 0,01466908 ! hexose catabolic process GO:0019320 104 67 2,000 4,756E-04 0,01448339 ! respiratory tube development GO:0030323 150 70 2,000 5,408E-04 0,01626417 ! respiratory system development GO:0060541 153 72 2,000 5,873E-04 0,01744498 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 5,906E-04 0,01732834 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,906E-04 0,01711956 ! neuron recognition GO:0008038 35 16 1,000 5,906E-04 0,01691576 ! learning or memory GO:0007611 147 73 2,000 6,115E-04 0,01730859 ! organelle localization GO:0051640 136 74 2,000 6,363E-04 0,01780148 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,683E-04 0,01848313 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 6,683E-04 0,0182731 ! monosaccharide catabolic process GO:0046365 115 76 2,000 6,878E-04 0,01859453 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,508E-04 0,02007111 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 7,508E-04 0,01985055 ! lipid phosphorylation GO:0046834 35 19 1,000 8,379E-04 0,02191277 ! protein export from nucleus GO:0006611 36 19 1,000 8,379E-04 0,02167715 ! response to oxygen levels GO:0070482 176 83 2,000 8,889E-04 0,02275221 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,296E-04 0,0235443 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 9,296E-04 0,02329905 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 9,296E-04 0,02305885 ! detection of chemical stimulus GO:0009593 37 20 1,000 9,296E-04 0,02282356 ! peptidyl-serine modification GO:0018209 43 20 1,000 9,296E-04 0,02259302 ! alcohol catabolic process GO:0046164 130 86 2,000 9,853E-04 0,02370689 ! regulation of protein transport GO:0051223 154 87 2,000 1,019E-03 0,02427138 GO:0070201|regulation of establishment of protein localization, ! vasodilation GO:0042311 39 21 1,000 1,026E-03 0,02420147 ! cellular respiration GO:0045333 135 88 2,000 1,053E-03 0,02460049 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,127E-03 0,02607163 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,127E-03 0,02582333 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 1,232E-03 0,02797507 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 1,232E-03 0,02771362 GO:0006099|tricarboxylic acid cycle, ! biogenic amine metabolic process GO:0006576 155 94 2,000 1,274E-03 0,02838341 ! forebrain development GO:0030900 188 95 2,000 1,314E-03 0,02899342 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 1,314E-03 0,02872984 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,343E-03 0,02910113 ! regulation of protein localization GO:0032880 176 97 2,000 1,395E-03 0,02996013 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 1,457E-03 0,03102657 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,457E-03 0,0307544 ! coenzyme catabolic process GO:0009109 39 25 1,000 1,457E-03 0,03048697 ! somitogenesis GO:0001756 43 25 1,000 1,457E-03 0,03022415 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 1,576E-03 0,03241572 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,576E-03 0,03214101 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,576E-03 0,03187092 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,7E-03 0,03408408 ! protein amino acid acylation GO:0043543 55 27 1,000 1,7E-03 0,03380239 ! superoxide metabolic process GO:0006801 38 27 1,000 1,7E-03 0,03352532 ! glutathione metabolic process GO:0006749 39 27 1,000 1,7E-03 0,03325276 ! dendrite development GO:0016358 59 28 1,000 1,828E-03 0,03547017 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,828E-03 0,03518641 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 1,828E-03 0,03490715 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 1,961E-03 0,03714353 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 1,961E-03 0,03685334 ! cofactor catabolic process GO:0051187 51 30 1,000 2,098E-03 0,03912263 ! response to hydrogen peroxide GO:0042542 50 32 1,000 2,385E-03 0,04413698 ! spindle organization GO:0007051 46 32 1,000 2,385E-03 0,04380006 ! response to ionizing radiation GO:0010212 65 32 1,000 2,385E-03 0,04346824 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,385E-03 0,04314141 ! post-embryonic development GO:0009791 69 33 1,000 2,535E-03 0,04551572 ! cell fate specification GO:0001708 52 33 1,000 2,535E-03 0,04517857 ! calcium-mediated signaling GO:0019722 62 35 1,000 2,848E-03 0,05039028 ! regulation of microtubule-based process GO:0032886 78 35 1,000 2,848E-03 0,05002247 ! aerobic respiration GO:0009060 55 36 1,000 3,011E-03 0,05250474 ! RNA export from nucleus GO:0006405 56 37 1,000 3,179E-03 0,05502562 ! glycogen metabolic process GO:0005977 61 37 1,000 3,179E-03 0,05463258 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 3,179E-03 0,05424511 ! glucan metabolic process GO:0044042 62 38 1,000 3,351E-03 0,05677289 GO:0006073|cellular glucan metabolic process, ! segmentation GO:0035282 67 39 1,000 3,527E-03 0,0593369 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 4,08E-03 0,06816947 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 4,08E-03 0,06769933 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 4,08E-03 0,06723564 ! regulation of tube size GO:0035150 71 42 1,000 4,08E-03 0,06677826 GO:0050880|regulation of blood vessel size, ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 4,273E-03 0,06946153 ! epithelial cell differentiation GO:0030855 79 43 1,000 4,273E-03 0,06899534 ! energy reserve metabolic process GO:0006112 74 43 1,000 4,273E-03 0,06853538 ! double-strand break repair GO:0006302 81 44 1,000 4,47E-03 0,07121995 ! cell growth GO:0016049 84 45 1,000 4,671E-03 0,0739347 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 4,876E-03 0,07667875 ! response to insulin stimulus GO:0032868 95 46 1,000 4,876E-03 0,07618083 ! positive regulation of DNA binding GO:0043388 73 47 1,000 5,085E-03 0,07893862 ! vascular process in circulatory system GO:0003018 80 47 1,000 5,085E-03 0,07843261 ! protein homooligomerization GO:0051260 76 47 1,000 5,085E-03 0,07793304 ! positive regulation of cell cycle GO:0045787 89 48 1,000 5,299E-03 0,08068952 ! peptide metabolic process GO:0006518 76 49 1,000 5,516E-03 0,0834728 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 5,516E-03 0,0829511 ! histone modification GO:0016570 91 50 1,000 5,738E-03 0,08574618 ! positive regulation of binding GO:0051099 78 51 1,000 5,963E-03 0,08856653 ! covalent chromatin modification GO:0016569 101 52 1,000 6,193E-03 0,0914114 ! respiratory electron transport chain GO:0022904 76 53 1,000 6,426E-03 0,09428006 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 6,426E-03 0,09370867 ! response to UV GO:0009411 104 53 1,000 6,426E-03 0,09314416 ! activation of phospholipase C activity GO:0007202 103 54 1,000 6,664E-03 0,09600809 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 6,664E-03 0,09543662 ! cell recognition GO:0008037 85 54 1,000 6,664E-03 0,0948719 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 6,905E-03 0,09773104 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 6,905E-03 0,09715951 ! aging GO:0007568 103 55 1,000 6,905E-03 0,09659463 ! nuclear export GO:0051168 97 55 1,000 6,905E-03 0,09603628 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 7,4E-03 0,10232447 ! positive regulation of cell migration GO:0030335 126 57 1,000 7,4E-03 0,10173976 ! lipid modification GO:0030258 97 57 1,000 7,4E-03 0,10116169 ! regulation of phospholipase activity GO:0010517 106 57 1,000 7,4E-03 0,10059015 ! positive regulation of lipase activity GO:0060193 108 58 1,000 7,653E-03 0,10344733 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 8,171E-03 0,10983182 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 8,436E-03 0,11276062 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 9,253E-03 0,12299972 ! positive regulation of cell motion GO:0051272 146 64 1,000 9,253E-03 0,1223239 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01010414 0,13284466 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01039528 0,13592958 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01123918 0,14617014 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01123918 0,14538428 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01123918 0,14460682 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01123918 0,14383764 ! neuron fate determination GO:0048664 7 5 0,000 0,01123918 0,14307659 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01123918 0,14232356 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01123918 0,14157841 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01123918 0,14084102 ! polyol transport GO:0015791 12 5 0,000 0,01123918 0,14011127 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01123918 0,13938905 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01123918 0,13867424 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01123918 0,13796671 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01123918 0,13726638 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01123918 0,13657311 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01123918 0,13588681 ! female meiosis GO:0007143 7 5 0,000 0,01123918 0,13520738 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01123918 0,13453471 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01123918 0,13386869 ! cobalt ion transport GO:0006824 11 5 0,000 0,01123918 0,13320924 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01123918 0,13255625 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01123918 0,13190964 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01123918 0,1312693 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01123918 0,13063515 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01123918 0,1300071 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01123918 0,12938505 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01123918 0,12876893 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01123918 0,12815865 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01123918 0,12755413 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01123918 0,12695529 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01123918 0,12636204 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01123918 0,12577431 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01123918 0,12519202 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01123918 0,1246151 ! negative chemotaxis GO:0050919 14 5 0,000 0,01123918 0,12404347 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01123918 0,12347706 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01123918 0,1229158 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01123918 0,12235962 ! behavioral response to pain GO:0048266 9 5 0,000 0,01123918 0,12180845 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01123918 0,12126222 ! Notch receptor processing GO:0007220 8 5 0,000 0,01123918 0,12072087 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01123918 0,12018434 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01123918 0,11965255 ! micturition GO:0060073 9 5 0,000 0,01123918 0,11912544 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01123918 0,11860296 ! copulation GO:0007620 9 5 0,000 0,01123918 0,11808505 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01123918 0,11757163 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01123918 0,11706267 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01123918 0,11655809 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01123918 0,11605784 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01123918 0,11556186 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01123918 0,11507011 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01123918 0,11458253 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01123918 0,11409905 ! grooming behavior GO:0007625 6 5 0,000 0,01123918 0,11361965 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01123918 0,11314425 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01123918 0,11267282 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01123918 0,11220529 ! response to protozoan GO:0001562 10 5 0,000 0,01123918 0,11174164 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01123918 0,11128179 ! lymph vessel development GO:0001945 10 5 0,000 0,01123918 0,11082572 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01123918 0,11037337 ! endochondral ossification GO:0001958 16 5 0,000 0,01123918 0,1099247 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01123918 0,10947966 ! parathyroid gland development GO:0060017 13 5 0,000 0,01123918 0,10903821 ! anagen GO:0042640 6 5 0,000 0,01123918 0,1086003 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01123918 0,1081659 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01123918 0,10773496 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01123918 0,10730744 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01123918 0,1068833 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01123918 0,1064625 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01123918 0,106045 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01123918 0,10563077 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01123918 0,10521975 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01123918 0,10481192 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01123918 0,10440724 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01123918 0,10400568 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01123918 0,10360719 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01123918 0,10321174 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01123918 0,1028193 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01123918 0,10242983 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01123918 0,10204331 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01123918 0,10165968 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01123918 0,10127894 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01123918 0,10090103 ! histidine catabolic process GO:0006548 6 5 0,000 0,01123918 0,10052593 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01123918 0,10015361 ! microvillus organization GO:0032528 7 5 0,000 0,01123918 0,09978404 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01123918 0,09941719 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01123918 0,09905303 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01123918 0,09869152 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01123918 0,09833264 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01123918 0,09797636 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01123918 0,09762266 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01123918 0,0972715 ! polyol catabolic process GO:0046174 7 5 0,000 0,01123918 0,09692285 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01123918 0,0965767 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01123918 0,09623301 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01123918 0,09589176 ! muscle cell migration GO:0014812 8 5 0,000 0,01123918 0,09555292 ! mitochondrial fission GO:0000266 8 5 0,000 0,01123918 0,09521646 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01123918 0,09488237 ! mRNA transcription GO:0009299 9 5 0,000 0,01123918 0,09455062 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01123918 0,09422117 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01123918 0,09389401 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01123918 0,09356912 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01123918 0,09324647 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01123918 0,09292603 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01123918 0,09260779 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01123918 0,09229173 ! response to food GO:0032094 6 5 0,000 0,01123918 0,09197781 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01123918 0,09166602 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01123918 0,09135634 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01123918 0,09104874 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01123918 0,09074321 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01123918 0,09043972 ! forebrain neuron development GO:0021884 13 5 0,000 0,01123918 0,09013825 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01123918 0,08983879 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01123918 0,08954131 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01123918 0,0892458 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01123918 0,08895222 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01123918 0,08866058 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01123918 0,08837084 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01123918 0,08808298 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01123918 0,087797 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01123918 0,08751287 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01123918 0,08723057 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01123918 0,08695008 ! basic amino acid transport GO:0015802 11 5 0,000 0,01123918 0,0866714 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01123918 0,08639449 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01123918 0,08611935 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01123918 0,08584596 ! depyrimidination GO:0045008 10 5 0,000 0,01123918 0,08557429 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01123918 0,08530434 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01123918 0,08503609 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01123918 0,08476952 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01123918 0,08450461 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01123918 0,08424136 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01123918 0,08397974 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01123918 0,08371974 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01123918 0,08346135 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01123918 0,08320454 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01123918 0,08294931 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01123918 0,08269565 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01123918 0,08244352 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01123918 0,08219294 ! response to arsenic GO:0046685 10 5 0,000 0,01123918 0,08194387 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01123918 0,0816963 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01123918 0,08145023 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01123918 0,08120563 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01123918 0,0809625 ! response to cadmium ion GO:0046686 7 5 0,000 0,01123918 0,08072082 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01123918 0,08048058 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01123918 0,08024177 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01123918 0,08000437 ! decidualization GO:0046697 11 5 0,000 0,01123918 0,07976837 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01123918 0,07953375 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01123918 0,07930052 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01123918 0,07906864 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01123918 0,07883812 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01123918 0,07860894 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01123918 0,07838109 ! neural tube patterning GO:0021532 7 5 0,000 0,01123918 0,07815455 ! embryonic cleavage GO:0040016 6 5 0,000 0,01123918 0,07792933 ! peroxisome fission GO:0016559 5 5 0,000 0,01123918 0,07770539 ! histone demethylation GO:0016577 10 5 0,000 0,01123918 0,07748274 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01123918 0,07726136 ! mitotic recombination GO:0006312 9 5 0,000 0,01123918 0,07704124 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01123918 0,07682237 ! metaphase plate congression GO:0051310 7 5 0,000 0,01123918 0,07660475 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01123918 0,07638835 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01123918 0,07617317 ! enteric nervous system development GO:0048484 8 5 0,000 0,01123918 0,0759592 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01123918 0,07574643 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01123918 0,07553485 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01123918 0,07532445 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01123918 0,07511521 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01123918 0,07490714 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01123918 0,07470021 ! plasminogen activation GO:0031639 5 5 0,000 0,01123918 0,07449442 ! B cell homeostasis GO:0001782 13 5 0,000 0,01123918 0,07428977 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01123918 0,07408624 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01123918 0,07388381 ! metaphase GO:0051323 8 5 0,000 0,01123918 0,0736825 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01123918 0,07348227 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01123918 0,07328313 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01123918 0,07308507 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01123918 0,07288808 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01123918 0,07269214 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01123918 0,07249725 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01123918 0,07230341 ! response to redox state GO:0051775 5 5 0,000 0,01123918 0,0721106 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01123918 0,07191882 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01123918 0,07172805 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01123918 0,0715383 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01123918 0,07134954 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01123918 0,07116178 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01123918 0,070975 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01123918 0,0707892 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01123918 0,07060438 ! striatum development GO:0021756 9 5 0,000 0,01123918 0,07042051 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01123918 0,0702376 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01123918 0,07005564 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01123918 0,06987461 ! glial cell migration GO:0008347 11 5 0,000 0,01123918 0,06969453 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01123918 0,06951536 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01123918 0,06933712 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01123918 0,06915978 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01123918 0,06898336 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01123918 0,06880783 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01123918 0,06863319 ! neuroprotection GO:0043526 6 5 0,000 0,01123918 0,06845943 ! neural plate development GO:0001840 8 5 0,000 0,01123918 0,06828656 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01123918 0,06811455 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01123918 0,06794341 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01123918 0,06777312 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01123918 0,06760369 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01123918 0,0674351 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01123918 0,06726735 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01123918 0,06710044 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01123918 0,06693435 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01123918 0,06676908 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01123918 0,06660462 ! spindle assembly GO:0051225 6 5 0,000 0,01123918 0,06644097 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01123918 0,06627813 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01123918 0,06611608 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01123918 0,06595482 ! drug metabolic process GO:0017144 6 5 0,000 0,01123918 0,06579435 ! stem cell division GO:0017145 11 5 0,000 0,01123918 0,06563465 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01123918 0,06547573 ! organ regeneration GO:0031100 7 5 0,000 0,01123918 0,06531757 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01123918 0,06516018 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01123918 0,06500355 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01123918 0,06484766 ! regulation of caspase activity GO:0043281 122 72 1,000 0,0115966 0,06674983 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0115966 0,06659053 ! regulation of blood pressure GO:0008217 125 73 1,000 0,01190604 0,06820463 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01221909 0,06983168 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01221909 0,0696662 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01347204 0,07662819 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01347204 0,07644747 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01347204 0,07626759 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01347204 0,07608856 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01347204 0,07591036 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01347204 0,075733 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01347204 0,07555647 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01347204 0,07538076 ! sleep GO:0030431 13 6 0,000 0,01347204 0,07520586 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01347204 0,07503177 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01347204 0,07485849 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01347204 0,074686 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01347204 0,07451431 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01347204 0,07434341 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01347204 0,07417328 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01347204 0,07400394 ! forebrain regionalization GO:0021871 8 6 0,000 0,01347204 0,07383537 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01347204 0,07366756 ! male meiosis GO:0007140 7 6 0,000 0,01347204 0,07350051 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01347204 0,07333422 ! response to zinc ion GO:0010043 9 6 0,000 0,01347204 0,07316868 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01347204 0,07300389 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01347204 0,07283983 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01347204 0,07267651 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01347204 0,07251393 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01347204 0,07235207 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01347204 0,07219093 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01347204 0,0720305 ! protein refolding GO:0042026 15 6 0,000 0,01347204 0,07187079 ! opsonization GO:0008228 8 6 0,000 0,01347204 0,07171178 ! mating behavior GO:0007617 7 6 0,000 0,01347204 0,07155348 ! neuron remodeling GO:0016322 15 6 0,000 0,01347204 0,07139587 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01347204 0,07123896 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01347204 0,07108273 ! equilibrioception GO:0050957 14 6 0,000 0,01347204 0,07092719 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01347204 0,07077233 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01347204 0,07061814 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01347204 0,07046462 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01347204 0,07031177 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01347204 0,07015958 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01347204 0,07000805 ! toxin metabolic process GO:0009404 11 6 0,000 0,01347204 0,06985717 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01347204 0,06970694 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01347204 0,06955735 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01347204 0,06940841 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01347204 0,0692601 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01347204 0,06911242 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01347204 0,06896537 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01347204 0,06881895 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01347204 0,06867315 ! thymic T cell selection GO:0045061 12 6 0,000 0,01347204 0,06852796 ! protein lipoylation GO:0009249 10 6 0,000 0,01347204 0,06838339 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01347204 0,06823942 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01347204 0,06809606 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01347204 0,0679533 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01347204 0,06781114 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01347204 0,06766957 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01347204 0,06752859 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01347204 0,0673882 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01347204 0,06724839 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01347204 0,06710916 ! hyperosmotic response GO:0006972 9 6 0,000 0,01347204 0,06697051 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01347204 0,06683242 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01347204 0,06669491 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01347204 0,06655796 ! urea metabolic process GO:0019627 7 6 0,000 0,01347204 0,06642157 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01347204 0,06628574 ! neutrophil activation GO:0042119 8 6 0,000 0,01347204 0,06615046 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01347204 0,06601573 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01347204 0,06588156 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01347204 0,06574792 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01347204 0,06561483 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01347204 0,06548227 ! neuron apoptosis GO:0051402 9 6 0,000 0,01347204 0,06535025 ! nucleoside salvage GO:0043174 9 6 0,000 0,01347204 0,06521876 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01347204 0,0650878 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01347204 0,06495737 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01347204 0,06482745 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01347204 0,06469805 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01347204 0,06456917 ! carnitine transport GO:0015879 10 6 0,000 0,01347204 0,06444081 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01347204 0,06431295 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01347204 0,0641856 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01347204 0,06405875 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01347204 0,0639324 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01347204 0,06380655 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01347204 0,06368119 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01347204 0,06355632 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01347204 0,06343195 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01347204 0,06330806 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01347204 0,06318465 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01347204 0,06306172 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01347204 0,06293927 ! neural nucleus development GO:0048857 14 6 0,000 0,01347204 0,0628173 ! response to UV-C GO:0010225 11 6 0,000 0,01347204 0,06269579 ! astrocyte development GO:0014002 15 6 0,000 0,01347204 0,06257476 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01347204 0,06245419 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01347204 0,06233409 ! interaction with symbiont GO:0051702 13 6 0,000 0,01347204 0,06221444 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01347204 0,06209526 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01347204 0,06197653 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01347204 0,06185825 ! response to copper ion GO:0046688 10 6 0,000 0,01347204 0,06174043 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01347204 0,06162305 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01347204 0,06150612 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01347204 0,06138963 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01347204 0,06127358 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01347204 0,06115797 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01347204 0,0610428 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01347204 0,06092806 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01347204 0,06081374 ! hair follicle maturation GO:0048820 7 6 0,000 0,01347204 0,06069986 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01347204 0,0605864 ! Schwann cell development GO:0014044 15 6 0,000 0,01347204 0,06047337 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01347204 0,06036076 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01347204 0,06024856 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01347204 0,06013678 ! subpallium development GO:0021544 10 6 0,000 0,01347204 0,06002542 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01347204 0,05991446 ! histone ubiquitination GO:0016574 8 6 0,000 0,01347204 0,05980392 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01347204 0,05969379 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01347204 0,05958405 ! G2 phase GO:0051319 16 6 0,000 0,01347204 0,05947473 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01347204 0,0593658 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01347204 0,05925727 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01347204 0,05914913 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01347204 0,05904139 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01347204 0,05893405 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01347204 0,05882709 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01347204 0,05872052 ! receptor internalization GO:0031623 10 6 0,000 0,01347204 0,05861433 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01347204 0,05850853 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01347204 0,05840311 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01347204 0,05829807 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01347204 0,0581934 ! protein deubiquitination GO:0016579 14 6 0,000 0,01347204 0,05808911 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01347204 0,0579852 ! protein destabilization GO:0031648 9 6 0,000 0,01347204 0,05788165 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01347204 0,05777848 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01347204 0,05767567 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01347204 0,05757322 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01347204 0,05747114 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01347204 0,05736943 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01347204 0,05726807 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01347204 0,05716706 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01347204 0,05706642 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01347204 0,05696613 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01347204 0,05686619 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01347204 0,05676659 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01347204 0,05666735 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01347204 0,05656846 ! catecholamine transport GO:0051937 9 6 0,000 0,01347204 0,05646991 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01347204 0,0563717 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01347204 0,05627383 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01347204 0,0561763 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01347204 0,05607911 ! maternal placenta development GO:0001893 12 6 0,000 0,01347204 0,05598225 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01347204 0,05588573 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01347204 0,05578954 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01347204 0,05569369 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01347204 0,05559816 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01347204 0,05550295 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01347204 0,05540808 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01347204 0,05531352 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,01350703 0,0553627 ! protein oligomerization GO:0051259 139 78 1,000 0,01350703 0,05526855 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01383786 0,05652612 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01383786 0,05643032 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01451002 0,05907125 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01451002 0,05897147 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01485132 0,06025678 ! tRNA transcription GO:0009304 14 7 0,000 0,01569993 0,06359263 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01569993 0,06348575 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01569993 0,06337923 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01569993 0,06327307 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01569993 0,06316726 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01569993 0,06306181 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01569993 0,0629567 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01569993 0,06285195 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01569993 0,06274754 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01569993 0,06264348 ! prostate gland development GO:0030850 13 7 0,000 0,01569993 0,06253977 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01569993 0,0624364 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01569993 0,06233337 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01569993 0,06223068 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01569993 0,06212832 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01569993 0,06202631 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01569993 0,06192463 GO:0046463|acylglycerol biosynthetic process, ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01569993 0,06182328 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01569993 0,06172226 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01569993 0,06162157 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01569993 0,06152121 ! glycolipid transport GO:0046836 10 7 0,000 0,01569993 0,06142117 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01569993 0,06132146 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01569993 0,06122208 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01569993 0,06112301 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01569993 0,06102427 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01569993 0,06092584 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01569993 0,06082773 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01569993 0,06072994 ! mRNA stabilization GO:0048255 18 7 0,000 0,01569993 0,06063246 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01569993 0,06053529 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01569993 0,06043843 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01569993 0,06034189 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01569993 0,06024565 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01569993 0,06014972 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01569993 0,06005409 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01569993 0,05995876 ! lipoprotein transport GO:0042953 14 7 0,000 0,01569993 0,05986374 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01569993 0,05976902 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01569993 0,0596746 ! rhythmic behavior GO:0007622 15 7 0,000 0,01569993 0,05958048 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01569993 0,05948665 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01569993 0,05939312 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01569993 0,05929988 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01569993 0,05920693 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01569993 0,05911427 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01569993 0,05902191 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01569993 0,05892983 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01569993 0,05883804 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01569993 0,05874653 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01569993 0,05865531 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01569993 0,05856437 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01569993 0,05847372 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01569993 0,05838334 ! spinal cord patterning GO:0021511 13 7 0,000 0,01569993 0,05829324 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01569993 0,05820342 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01569993 0,05811388 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01569993 0,05802461 ! adrenal gland development GO:0030325 17 7 0,000 0,01569993 0,05793562 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01569993 0,05784689 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01569993 0,05775844 ! ovulation GO:0030728 9 7 0,000 0,01569993 0,05767026 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01569993 0,05758235 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01569993 0,05749471 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01569993 0,05740733 ! microtubule nucleation GO:0007020 20 7 0,000 0,01569993 0,05732021 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01569993 0,05723337 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01569993 0,05714678 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01569993 0,05706046 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01569993 0,05697439 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01569993 0,05688859 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01569993 0,05680304 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01569993 0,05671775 ! galactose metabolic process GO:0006012 13 7 0,000 0,01569993 0,05663272 ! vesicle fusion GO:0006906 17 7 0,000 0,01569993 0,05654794 ! response to dietary excess GO:0002021 8 7 0,000 0,01569993 0,05646341 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01569993 0,05637914 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01569993 0,05629511 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01569993 0,05621134 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01569993 0,05612782 ! organ growth GO:0035265 15 7 0,000 0,01569993 0,05604454 ! purine salvage GO:0043101 10 7 0,000 0,01569993 0,05596151 ! nucleoside transport GO:0015858 8 7 0,000 0,01569993 0,05587873 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01569993 0,05579619 ! parturition GO:0007567 14 7 0,000 0,01569993 0,0557139 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01569993 0,05563184 ! rRNA modification GO:0000154 14 7 0,000 0,01569993 0,05555003 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01569993 0,05546846 ! spindle checkpoint GO:0031577 15 7 0,000 0,01569993 0,05538713 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01569993 0,05530603 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01569993 0,05522518 ! macrophage differentiation GO:0030225 11 7 0,000 0,01569993 0,05514456 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01569993 0,05506417 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01569993 0,05498402 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01569993 0,0549041 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01569993 0,05482441 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01569993 0,05474496 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01569993 0,05466573 ! fibrinolysis GO:0042730 10 7 0,000 0,01569993 0,05458674 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01569993 0,05450797 ! eating behavior GO:0042755 7 7 0,000 0,01569993 0,05442943 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01569993 0,05435111 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01569993 0,05427302 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01569993 0,05419515 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01569993 0,05411751 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01569993 0,05404009 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01569993 0,05396289 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01569993 0,05388591 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01569993 0,05380915 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01569993 0,0537326 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01569993 0,05365628 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01569993 0,05358017 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01569993 0,05350428 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01569993 0,0534286 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01569993 0,05335314 ! regulation of meiosis GO:0040020 12 7 0,000 0,01569993 0,05327789 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01569993 0,05320285 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01569993 0,05312802 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01569993 0,0530534 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01569993 0,05297899 ! transcription termination GO:0006353 13 7 0,000 0,01569993 0,05290479 ! response to tumor cell GO:0002347 13 7 0,000 0,01569993 0,0528308 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01569993 0,05275701 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01569993 0,05268343 ! anaphase GO:0051322 17 7 0,000 0,01569993 0,05261006 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01569993 0,05253689 ! axonal fasciculation GO:0007413 18 7 0,000 0,01569993 0,05246392 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01569993 0,05239115 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01569993 0,05231859 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01569993 0,05224623 ! diuresis GO:0030146 12 7 0,000 0,01569993 0,05217406 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01569993 0,0521021 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01569993 0,05203033 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01569993 0,05195876 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01569993 0,05188739 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01569993 0,05181622 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01569993 0,05174523 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01569993 0,05167445 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01569993 0,05160385 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01569993 0,05153345 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01569993 0,05146324 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01569993 0,05139323 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01569993 0,0513234 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01569993 0,05125376 ! lymph node development GO:0048535 10 7 0,000 0,01569993 0,05118431 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01569993 0,05111505 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01569993 0,05104597 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01569993 0,05097709 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01569993 0,05090838 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01569993 0,05083987 ! adult feeding behavior GO:0008343 9 7 0,000 0,01569993 0,05077153 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01569993 0,05070338 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01569993 0,05063542 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01569993 0,05056763 ! muscle adaptation GO:0043500 14 7 0,000 0,01569993 0,05050003 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01569993 0,05043261 ! retina homeostasis GO:0001895 12 7 0,000 0,01569993 0,05036536 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01569993 0,0502983 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01569993 0,05023141 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01569993 0,0501647 ! protein prenylation GO:0018342 18 7 0,000 0,01569993 0,05009817 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01569993 0,05003182 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01569993 0,04996564 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01569993 0,04989963 ! mitochondrion organization GO:0007005 148 86 1,000 0,01625088 0,0515826 ! regulation of DNA binding GO:0051101 155 88 1,000 0,01697105 0,05379756 ! ossification GO:0001503 188 90 1,000 0,01770464 0,05604915 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01792286 0,05666543 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01792286 0,05659106 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01792286 0,05651689 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01792286 0,05644292 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01792286 0,05636914 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01792286 0,05629555 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01792286 0,05622215 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01792286 0,05614894 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01792286 0,05607593 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01792286 0,0560031 ! meiotic prophase I GO:0007128 13 8 0,000 0,01792286 0,05593047 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01792286 0,05585802 ! oligopeptide transport GO:0006857 15 8 0,000 0,01792286 0,05578576 ! UTP metabolic process GO:0046051 8 8 0,000 0,01792286 0,05571368 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01792286 0,05564179 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01792286 0,05557009 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01792286 0,05549857 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01792286 0,05542724 ! succinate metabolic process GO:0006105 14 8 0,000 0,01792286 0,05535608 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01792286 0,05528511 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01792286 0,05521433 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01792286 0,05514372 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01792286 0,05507329 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01792286 0,05500305 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01792286 0,05493298 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01792286 0,05486309 ! reflex GO:0060004 16 8 0,000 0,01792286 0,05479338 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01792286 0,05472384 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01792286 0,05465449 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01792286 0,0545853 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01792286 0,0545163 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01792286 0,05444746 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01792286 0,0543788 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01792286 0,05431031 ! pigment granule organization GO:0048753 16 8 0,000 0,01792286 0,054242 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01792286 0,05417386 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01792286 0,05410588 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01792286 0,05403808 ! histidine metabolic process GO:0006547 16 8 0,000 0,01792286 0,05397045 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01792286 0,05390299 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01792286 0,05383569 ! glycine catabolic process GO:0006546 13 8 0,000 0,01792286 0,05376857 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01792286 0,05370161 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01792286 0,05363481 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01792286 0,05356819 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01792286 0,05350172 ! melanin metabolic process GO:0006582 15 8 0,000 0,01792286 0,05343543 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01792286 0,05336929 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01792286 0,05330332 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01792286 0,05323752 ! macrophage activation GO:0042116 12 8 0,000 0,01792286 0,05317187 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01792286 0,05310639 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01792286 0,05304107 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01792286 0,05297591 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01792286 0,05291091 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01792286 0,05284607 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01792286 0,05278138 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01792286 0,05271686 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01792286 0,05265249 ! osteoblast development GO:0002076 16 8 0,000 0,01792286 0,05258828 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01792286 0,05252423 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01792286 0,05246033 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01792286 0,05239659 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01792286 0,052333 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01792286 0,05226956 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01792286 0,05220628 ! response to UV-B GO:0010224 16 8 0,000 0,01792286 0,05214316 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01792286 0,05208018 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01792286 0,05201736 ! intermediate filament organization GO:0045109 12 8 0,000 0,01792286 0,05195469 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01792286 0,05189217 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01792286 0,0518298 ! cellular extravasation GO:0045123 12 8 0,000 0,01792286 0,05176757 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01792286 0,0517055 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01792286 0,05164358 ! response to antibiotic GO:0046677 11 8 0,000 0,01792286 0,05158181 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01792286 0,05152018 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01792286 0,0514587 ! DNA topological change GO:0006265 12 8 0,000 0,01792286 0,05139737 ! response to tropane GO:0014073 15 8 0,000 0,01792286 0,05133618 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01792286 0,05127514 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01792286 0,05121424 ! melanosome transport GO:0032402 13 8 0,000 0,01792286 0,05115349 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01792286 0,05109288 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01792286 0,05103241 ! mast cell activation GO:0045576 14 8 0,000 0,01792286 0,05097209 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01792286 0,05091191 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01792286 0,05085187 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01792286 0,05079198 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01792286 0,05073222 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01792286 0,05067261 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01792286 0,05061313 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01792286 0,0505538 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01792286 0,0504946 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01792286 0,05043554 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01792286 0,05037662 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01792286 0,05031784 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01792286 0,0502592 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01792286 0,05020069 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01792286 0,05014231 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01792286 0,05008408 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01792286 0,05002597 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01792286 0,04996801 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01792286 0,04991017 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01792286 0,04985247 ! hormone catabolic process GO:0042447 17 8 0,000 0,01792286 0,04979491 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01792286 0,04973747 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01792286 0,04968017 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01792286 0,049623 ! ATP catabolic process GO:0006200 11 8 0,000 0,01792286 0,04956596 ! blastocyst growth GO:0001832 19 8 0,000 0,01792286 0,04950906 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01792286 0,04945228 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01792286 0,04939564 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01792286 0,04933912 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01792286 0,04928273 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01792286 0,04922647 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01792286 0,04917034 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01792286 0,04911434 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01792286 0,04905846 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01792286 0,04900272 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01792286 0,04894709 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01792286 0,0488916 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01792286 0,04883623 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01792286 0,04878098 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01792286 0,04872586 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01792286 0,04867087 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01792286 0,048616 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01792286 0,04856125 ! bone development GO:0060348 189 91 1,000 0,01807642 0,04892223 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,01882988 0,05090416 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01959644 0,05291698 ! detection of stimulus GO:0051606 151 96 1,000 0,01998458 0,05390459 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02014084 0,05426524 ! axon extension GO:0048675 15 9 0,000 0,02014084 0,05420454 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02014084 0,05414397 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02014084 0,05408354 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02014084 0,05402325 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02014084 0,05396309 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02014084 0,05390307 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02014084 0,05384317 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02014084 0,05378341 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02014084 0,05372379 ! phosphate transport GO:0006817 19 9 0,000 0,02014084 0,05366429 ! reproductive behavior GO:0019098 19 9 0,000 0,02014084 0,05360493 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02014084 0,0535457 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02014084 0,0534866 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02014084 0,05342763 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02014084 0,05336878 ! GTP metabolic process GO:0046039 9 9 0,000 0,02014084 0,05331007 ! RNA methylation GO:0001510 15 9 0,000 0,02014084 0,05325149 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02014084 0,05319304 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02014084 0,05313471 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02014084 0,05307651 ! artery development GO:0060840 24 9 0,000 0,02014084 0,05301844 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02014084 0,0529605 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02014084 0,05290268 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02014084 0,05284499 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02014084 0,05278743 ! chemosensory behavior GO:0007635 20 9 0,000 0,02014084 0,05272999 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02014084 0,05267267 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02014084 0,05261548 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02014084 0,05255841 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02014084 0,05250147 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02014084 0,05244465 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02014084 0,05238795 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02014084 0,05233138 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02014084 0,05227493 ! protein targeting to ER GO:0045047 22 9 0,000 0,02014084 0,0522186 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02014084 0,05216239 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02014084 0,0521063 ! T cell selection GO:0045058 23 9 0,000 0,02014084 0,05205033 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02014084 0,05199448 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02014084 0,05193875 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02014084 0,05188314 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02014084 0,05182765 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02014084 0,05177228 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02014084 0,05171703 ! mannose metabolic process GO:0006013 13 9 0,000 0,02014084 0,05166189 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02014084 0,05160688 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02014084 0,05155197 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02014084 0,05149719 ! receptor clustering GO:0043113 18 9 0,000 0,02014084 0,05144252 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02014084 0,05138797 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02014084 0,05133353 ! ruffle organization GO:0031529 15 9 0,000 0,02014084 0,05127921 ! retinol metabolic process GO:0042572 18 9 0,000 0,02014084 0,05122501 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02014084 0,05117091 ! behavioral fear response GO:0001662 22 9 0,000 0,02014084 0,05111694 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02014084 0,05106307 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02014084 0,05100932 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02014084 0,05095568 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02014084 0,05090216 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02014084 0,05084875 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02014084 0,05079545 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02014084 0,05074226 ! segment specification GO:0007379 13 9 0,000 0,02014084 0,05068918 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02014084 0,05063621 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02014084 0,05058336 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02014084 0,05053061 ! response to amine stimulus GO:0014075 13 9 0,000 0,02014084 0,05047798 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02014084 0,05042545 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02014084 0,05037303 ! erythrocyte development GO:0048821 15 9 0,000 0,02014084 0,05032072 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02014084 0,05026852 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02014084 0,05021643 ! renal water homeostasis GO:0003091 14 9 0,000 0,02014084 0,05016445 ! postreplication repair GO:0006301 22 9 0,000 0,02014084 0,05011257 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02014084 0,0500608 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02014084 0,05000914 ! icosanoid secretion GO:0032309 15 9 0,000 0,02014084 0,04995758 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02014084 0,04990613 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02014084 0,04985479 ! regulation of cell division GO:0051302 15 9 0,000 0,02014084 0,04980355 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02014084 0,04975242 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02014084 0,04970139 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02014084 0,04965047 ! sterol catabolic process GO:0016127 11 9 0,000 0,02014084 0,04959965 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02014084 0,04954893 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02014084 0,04949832 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02014084 0,04944781 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02014084 0,04939741 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02014084 0,0493471 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02014084 0,0492969 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02014084 0,04924681 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02014084 0,04919681 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02014084 0,04914691 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02014084 0,04909712 ! purine base metabolic process GO:0006144 21 9 0,000 0,02014084 0,04904743 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02014084 0,04899783 ! pigment granule transport GO:0051904 17 9 0,000 0,02014084 0,04894834 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02014084 0,04889895 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02014084 0,04884965 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02014084 0,04880046 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02014084 0,04875136 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02014084 0,04870237 ! mitochondrion localization GO:0051646 15 9 0,000 0,02014084 0,04865347 ! interphase GO:0051325 213 98 1,000 0,02077052 0,05012425 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02116829 0,05103296 GO:0060538|skeletal muscle organ development, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02235389 0,05383728 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02235389 0,05378345 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02235389 0,05372972 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02235389 0,0536761 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02235389 0,05362258 ! synapsis GO:0007129 13 10 0,000 0,02235389 0,05356917 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02235389 0,05351587 ! N-glycan processing GO:0006491 20 10 0,000 0,02235389 0,05346267 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02235389 0,05340958 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02235389 0,05335659 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02235389 0,05330371 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02235389 0,05325094 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02235389 0,05319827 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02235389 0,0531457 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02235389 0,05309324 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02235389 0,05304088 ! androgen metabolic process GO:0008209 17 10 0,000 0,02235389 0,05298862 ! phospholipid efflux GO:0033700 16 10 0,000 0,02235389 0,05293646 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02235389 0,05288441 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02235389 0,05283246 ! lung alveolus development GO:0048286 26 10 0,000 0,02235389 0,05278062 ! pathogenesis GO:0009405 13 10 0,000 0,02235389 0,05272887 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02235389 0,05267723 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02235389 0,05262568 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02235389 0,05257424 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02235389 0,0525229 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02235389 0,05247166 ! endoderm development GO:0007492 16 10 0,000 0,02235389 0,05242051 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02235389 0,05236947 ! arginine catabolic process GO:0006527 13 10 0,000 0,02235389 0,05231853 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02235389 0,05226768 ! proline metabolic process GO:0006560 13 10 0,000 0,02235389 0,05221694 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02235389 0,05216629 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02235389 0,05211574 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02235389 0,05206529 ! V(D)J recombination GO:0033151 28 10 0,000 0,02235389 0,05201494 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02235389 0,05196468 ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02235389 0,05191452 ! B cell proliferation GO:0042100 18 10 0,000 0,02235389 0,05186446 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02235389 0,0518145 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02235389 0,05176463 ! multicellular organism growth GO:0035264 18 10 0,000 0,02235389 0,05171485 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02235389 0,05166518 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02235389 0,05161559 ! epithelial cell development GO:0002064 20 10 0,000 0,02235389 0,05156611 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02235389 0,05151671 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02235389 0,05146741 ! macroautophagy GO:0016236 17 10 0,000 0,02235389 0,05141821 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02235389 0,0513691 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02235389 0,05132008 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02235389 0,05127116 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02235389 0,05122233 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02235389 0,05117359 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02235389 0,05112495 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02235389 0,0510764 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02235389 0,05102794 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02235389 0,05097957 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02235389 0,0509313 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02235389 0,05088311 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02235389 0,05083502 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02235389 0,05078701 ! response to dsRNA GO:0043331 20 10 0,000 0,02235389 0,0507391 ! DNA ligation GO:0006266 19 10 0,000 0,02235389 0,05069128 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02235389 0,05064355 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02235389 0,05059591 ! melanosome localization GO:0032400 16 10 0,000 0,02235389 0,05054835 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02235389 0,05050089 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02235389 0,05045352 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02235389 0,05040623 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02235389 0,05035903 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02235389 0,05031192 ! mRNA cleavage GO:0006379 17 10 0,000 0,02235389 0,0502649 ! protein sumoylation GO:0016925 15 10 0,000 0,02235389 0,05021797 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02235389 0,05017113 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02235389 0,05012437 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02235389 0,0500777 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02235389 0,05003111 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02235389 0,04998462 ! salivary gland development GO:0007431 27 10 0,000 0,02235389 0,04993821 ! prophase GO:0051324 15 10 0,000 0,02235389 0,04989188 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02235389 0,04984564 ! apical protein localization GO:0045176 15 10 0,000 0,02235389 0,04979949 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02235389 0,04975342 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02235389 0,04970744 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02235389 0,04966154 ! midbrain development GO:0030901 13 10 0,000 0,02235389 0,04961573 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02235389 0,04957 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02235389 0,04952435 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02235389 0,04947879 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02235389 0,04943332 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02235389 0,04938792 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02235389 0,04934261 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02235389 0,04929739 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02235389 0,04925224 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02235389 0,04920718 ! oocyte development GO:0048599 17 10 0,000 0,02235389 0,0491622 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02235389 0,0491173 ! blastocyst formation GO:0001825 17 10 0,000 0,02235389 0,04907249 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02235389 0,04902776 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02235389 0,0489831 ! activation of innate immune response GO:0002218 12 10 0,000 0,02235389 0,04893853 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02235389 0,04889404 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02235389 0,04884963 ! response to nicotine GO:0035094 20 10 0,000 0,02235389 0,04880531 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02235389 0,04876106 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02235389 0,04871689 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02235389 0,0486728 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02456201 0,05343236 ! respiratory burst GO:0045730 17 11 0,000 0,02456201 0,05338409 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02456201 0,05333591 ! neuron fate specification GO:0048665 17 11 0,000 0,02456201 0,05328782 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02456201 0,05323981 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02456201 0,05319189 ! thyroid gland development GO:0030878 26 11 0,000 0,02456201 0,05314406 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02456201 0,05309631 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02456201 0,05304864 ! response to pain GO:0048265 24 11 0,000 0,02456201 0,05300107 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02456201 0,05295358 ! T cell proliferation GO:0042098 26 11 0,000 0,02456201 0,05290617 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02456201 0,05285885 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02456201 0,05281161 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02456201 0,05276446 ! bone resorption GO:0045453 16 11 0,000 0,02456201 0,05271739 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02456201 0,0526704 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02456201 0,0526235 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02456201 0,05257668 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02456201 0,05252995 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02456201 0,05248329 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02456201 0,05243673 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02456201 0,05239024 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02456201 0,05234384 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02456201 0,05229751 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02456201 0,05225127 ! lipid digestion GO:0044241 18 11 0,000 0,02456201 0,05220511 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02456201 0,05215904 ! UV protection GO:0009650 19 11 0,000 0,02456201 0,05211304 ! adult heart development GO:0007512 14 11 0,000 0,02456201 0,05206713 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02456201 0,05202129 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02456201 0,05197554 ! temperature homeostasis GO:0001659 17 11 0,000 0,02456201 0,05192987 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02456201 0,05188428 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02456201 0,05183876 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02456201 0,05179333 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02456201 0,05174798 ! regulation of organ growth GO:0046620 13 11 0,000 0,02456201 0,0517027 ! pigment granule localization GO:0051875 20 11 0,000 0,02456201 0,05165751 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02456201 0,05161239 ! vasoconstriction GO:0042310 18 11 0,000 0,02456201 0,05156736 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02456201 0,0515224 ! embryonic axis specification GO:0000578 18 11 0,000 0,02456201 0,05147752 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02456201 0,05143272 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02456201 0,05138799 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02456201 0,05134334 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02456201 0,05129878 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02456201 0,05125428 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02456201 0,05120987 ! zymogen activation GO:0031638 15 11 0,000 0,02456201 0,05116553 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02456201 0,05112127 ! nucleosome positioning GO:0016584 15 11 0,000 0,02456201 0,05107709 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02456201 0,05103298 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02456201 0,05098895 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02456201 0,05094499 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02456201 0,05090111 ! acid secretion GO:0046717 18 11 0,000 0,02456201 0,05085731 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02456201 0,05081358 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02456201 0,05076992 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02456201 0,05072634 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02456201 0,05068284 ! oocyte differentiation GO:0009994 18 11 0,000 0,02456201 0,05063941 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02456201 0,05059605 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02456201 0,05055277 ! cholesterol efflux GO:0033344 19 11 0,000 0,02456201 0,05050956 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02456201 0,05046643 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02456201 0,05042337 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02456201 0,05038038 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02456201 0,05033747 ! embryonic gut development GO:0048566 15 11 0,000 0,02456201 0,05029463 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02456201 0,05025186 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02456201 0,05020917 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02456201 0,05016654 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02456201 0,05012399 ! defense response to fungus GO:0050832 13 11 0,000 0,02456201 0,05008152 ! lysogeny GO:0030069 21 11 0,000 0,02456201 0,05003911 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02456201 0,04999678 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02456201 0,04995451 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02456201 0,04991232 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02456201 0,0498702 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02456201 0,04982815 ! nucleus localization GO:0051647 19 11 0,000 0,02456201 0,04978618 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02456201 0,04974427 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02676522 0,05416073 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02676522 0,05411522 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02676522 0,05406978 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02676522 0,05402442 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02676522 0,05397914 ! virus-host interaction GO:0019048 29 12 0,000 0,02676522 0,05393393 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02676522 0,05388879 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02676522 0,05384374 ! cartilage condensation GO:0001502 20 12 0,000 0,02676522 0,05379875 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02676522 0,05375385 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02676522 0,05370901 ! protein complex disassembly GO:0043241 27 12 0,000 0,02676522 0,05366426 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02676522 0,05361957 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02676522 0,05357497 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02676522 0,05353043 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02676522 0,05348597 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02676522 0,05344158 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02676522 0,05339727 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02676522 0,05335303 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02676522 0,05330886 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02676522 0,05326477 ! drug transport GO:0015893 16 12 0,000 0,02676522 0,05322075 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02676522 0,0531768 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02676522 0,05313293 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02676522 0,05308912 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02676522 0,05304539 ! focal adhesion formation GO:0048041 35 12 0,000 0,02676522 0,05300174 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02676522 0,05295815 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02676522 0,05291463 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02676522 0,05287119 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02676522 0,05282782 ! entry into host cell GO:0030260 32 12 0,000 0,02676522 0,05278452 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02676522 0,05274128 ! monoamine transport GO:0015844 18 12 0,000 0,02676522 0,05269812 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02676522 0,05265504 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02676522 0,05261202 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02676522 0,05256907 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02676522 0,05252619 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02676522 0,05248338 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02676522 0,05244064 ! protein homotetramerization GO:0051289 21 12 0,000 0,02676522 0,05239797 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02676522 0,05235537 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02676522 0,05231284 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02676522 0,05227038 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02676522 0,05222799 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02676522 0,05218566 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02676522 0,05214341 ! cranial nerve development GO:0021545 20 12 0,000 0,02676522 0,05210122 ! fucose catabolic process GO:0019317 22 12 0,000 0,02676522 0,0520591 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02676522 0,05201705 ! histone methylation GO:0016571 26 12 0,000 0,02676522 0,05197507 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02676522 0,05193315 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02676522 0,0518913 ! gland morphogenesis GO:0022612 29 12 0,000 0,02676522 0,05184952 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02676522 0,05180781 ! T cell homeostasis GO:0043029 25 12 0,000 0,02676522 0,05176616 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02676522 0,05172459 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02676522 0,05168307 ! spleen development GO:0048536 22 12 0,000 0,02676522 0,05164163 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02676522 0,05160025 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02676522 0,05155893 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02676522 0,05151769 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02676522 0,05147651 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02676522 0,05143539 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02676522 0,05139434 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02676522 0,05135336 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02676522 0,05131244 ! response to cold GO:0009409 17 12 0,000 0,02676522 0,05127158 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02676522 0,05123079 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02676522 0,05119007 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02896352 0,05535046 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02896352 0,05530653 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02896352 0,05526267 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02896352 0,05521888 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02896352 0,05517516 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02896352 0,05513151 ! lipid localization GO:0010876 28 13 0,000 0,02896352 0,05508793 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02896352 0,05504442 ! organelle fusion GO:0048284 32 13 0,000 0,02896352 0,05500097 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02896352 0,05495759 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02896352 0,05491429 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02896352 0,05487105 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02896352 0,05482788 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02896352 0,05478477 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02896352 0,05474174 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02896352 0,05469877 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02896352 0,05465587 ! methionine metabolic process GO:0006555 27 13 0,000 0,02896352 0,05461303 ! plasma membrane organization GO:0007009 24 13 0,000 0,02896352 0,05457027 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02896352 0,05452757 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02896352 0,05448493 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02896352 0,05444237 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02896352 0,05439987 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02896352 0,05435743 ! response to X-ray GO:0010165 25 13 0,000 0,02896352 0,05431507 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02896352 0,05427276 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02896352 0,05423053 ! exocrine system development GO:0035272 32 13 0,000 0,02896352 0,05418836 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02896352 0,05414625 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02896352 0,05410422 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02896352 0,05406224 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02896352 0,05402033 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02896352 0,05397849 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02896352 0,05393671 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02896352 0,053895 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02896352 0,05385335 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02896352 0,05381176 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02896352 0,05377024 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02896352 0,05372878 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02896352 0,05368739 ! ribosome assembly GO:0042255 17 13 0,000 0,02896352 0,05364606 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02896352 0,05360479 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02896352 0,05356359 ! chromatin silencing GO:0006342 26 13 0,000 0,02896352 0,05352245 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02896352 0,05348137 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02896352 0,05344036 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02896352 0,05339941 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02896352 0,05335852 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02896352 0,0533177 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02896352 0,05327693 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02896352 0,05323623 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02896352 0,0531956 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02896352 0,05315502 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02896352 0,0531145 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02896352 0,05307405 ! embryonic placenta development GO:0001892 23 13 0,000 0,02896352 0,05303366 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02896352 0,05299333 ! insulin secretion GO:0030073 23 13 0,000 0,02896352 0,05295306 ! actin filament polymerization GO:0030041 24 13 0,000 0,02896352 0,05291285 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02896352 0,05287271 ! acrosome reaction GO:0007340 18 13 0,000 0,02896352 0,05283262 ! rRNA transcription GO:0009303 25 14 0,000 0,03115693 0,05679059 ! lactation GO:0007595 26 14 0,000 0,03115693 0,0567476 ! reproductive cellular process GO:0048610 20 14 0,000 0,03115693 0,05670467 ! tRNA modification GO:0006400 20 14 0,000 0,03115693 0,05666181 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03115693 0,05661902 ! regulation of S phase GO:0033261 23 14 0,000 0,03115693 0,05657629 ! water transport GO:0006833 21 14 0,000 0,03115693 0,05653362 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03115693 0,05649102 ! non-recombinational repair GO:0000726 25 14 0,000 0,03115693 0,05644848 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03115693 0,056406 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03115693 0,05636359 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03115693 0,05632125 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03115693 0,05627896 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03115693 0,05623674 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03115693 0,05619459 ! palate development GO:0060021 31 14 0,000 0,03115693 0,05615249 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03115693 0,05611046 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03115693 0,0560685 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03115693 0,05602659 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03115693 0,05598475 ! arginine metabolic process GO:0006525 17 14 0,000 0,03115693 0,05594297 ! regulation of heart rate GO:0002027 24 14 0,000 0,03115693 0,05590125 ! organic alcohol transport GO:0015850 29 14 0,000 0,03115693 0,0558596 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03115693 0,055818 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03115693 0,05577647 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03115693 0,055735 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03115693 0,0556936 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03115693 0,05565225 ! L-amino acid transport GO:0015807 30 14 0,000 0,03115693 0,05561096 ! bone mineralization GO:0030282 17 14 0,000 0,03115693 0,05556974 ! stem cell development GO:0048864 43 14 0,000 0,03115693 0,05552858 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03115693 0,05548748 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03115693 0,05544643 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03115693 0,05540545 ! cerebellum development GO:0021549 21 14 0,000 0,03115693 0,05536453 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03115693 0,05532367 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03115693 0,05528288 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03115693 0,05524214 ! cofactor transport GO:0051181 26 14 0,000 0,03115693 0,05520146 ! NADP metabolic process GO:0006739 24 14 0,000 0,03115693 0,05516084 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03115693 0,05512028 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03115693 0,05507978 ! intestinal absorption GO:0050892 25 14 0,000 0,03115693 0,05503934 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03115693 0,05499896 ! oxygen transport GO:0015671 21 14 0,000 0,03115693 0,05495864 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03115693 0,05491837 ! male genitalia development GO:0030539 24 14 0,000 0,03115693 0,05487817 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03115693 0,05483802 ! regulation of axon extension GO:0030516 37 14 0,000 0,03115693 0,05479794 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03115693 0,05475791 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03334546 0,05856145 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03334546 0,05851873 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03334546 0,05847608 ! superoxide anion generation GO:0042554 20 15 0,000 0,03334546 0,05843349 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03334546 0,05839096 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03334546 0,0583485 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03334546 0,05830609 ! copper ion transport GO:0006825 20 15 0,000 0,03334546 0,05826375 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03334546 0,05822147 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03334546 0,05817925 ! sulfate transport GO:0008272 23 15 0,000 0,03334546 0,05813709 ! response to cAMP GO:0051591 22 15 0,000 0,03334546 0,05809499 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03334546 0,05805295 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03334546 0,05801098 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03334546 0,05796906 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03334546 0,05792721 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03334546 0,05788541 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03334546 0,05784368 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03334546 0,05780201 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03334546 0,05776039 ! pituitary gland development GO:0021983 29 15 0,000 0,03334546 0,05771884 ! vesicle coating GO:0006901 33 15 0,000 0,03334546 0,05767734 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03334546 0,05763591 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03334546 0,05759453 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03334546 0,05755322 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03334546 0,05751196 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03334546 0,05747076 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03334546 0,05742962 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03334546 0,05738854 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03334546 0,05734752 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03334546 0,05730656 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03334546 0,05726566 ! histone deacetylation GO:0016575 20 15 0,000 0,03334546 0,05722481 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03334546 0,05718402 ! tissue regeneration GO:0042246 26 15 0,000 0,03334546 0,05714329 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03334546 0,05710262 ! water homeostasis GO:0030104 27 15 0,000 0,03334546 0,05706201 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03334546 0,05702145 ! muscle maintenance GO:0046716 26 15 0,000 0,03334546 0,05698095 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03334546 0,05694051 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03334546 0,05690013 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03334546 0,0568598 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03334546 0,05681954 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03334546 0,05677932 ! cell killing GO:0001906 29 15 0,000 0,03334546 0,05673917 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03334546 0,05669907 ! detection of bacterium GO:0016045 18 15 0,000 0,03334546 0,05665903 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03334546 0,05661904 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03334546 0,05657911 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03334546 0,05653924 ! peptide hormone processing GO:0016486 23 15 0,000 0,03334546 0,05649942 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03552912 0,06015698 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03552912 0,06011467 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03552912 0,06007243 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03552912 0,06003024 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03552912 0,05998812 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03552912 0,05994605 ! bone remodeling GO:0046849 27 16 0,000 0,03552912 0,05990404 ! filopodium assembly GO:0046847 32 16 0,000 0,03552912 0,05986209 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03552912 0,0598202 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03552912 0,05977837 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03552912 0,0597366 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03552912 0,05969488 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03552912 0,05965322 ! startle response GO:0001964 28 16 0,000 0,03552912 0,05961162 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03552912 0,05957008 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03552912 0,0595286 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03552912 0,05948717 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03552912 0,0594458 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03552912 0,05940449 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03552912 0,05936324 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03552912 0,05932205 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03552912 0,05928091 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03552912 0,05923982 ! response to osmotic stress GO:0006970 25 16 0,000 0,03552912 0,0591988 ! lysosomal transport GO:0007041 26 16 0,000 0,03552912 0,05915783 ! fructose metabolic process GO:0006000 25 16 0,000 0,03552912 0,05911692 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03552912 0,05907607 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03552912 0,05903527 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03552912 0,05899453 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03552912 0,05895384 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03552912 0,05891321 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03552912 0,05887264 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03552912 0,05883212 ! DNA replication initiation GO:0006270 27 16 0,000 0,03552912 0,05879166 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03552912 0,05875125 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03552912 0,0587109 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03552912 0,0586706 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03552912 0,05863036 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03552912 0,05859018 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03552912 0,05855005 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03552912 0,05850997 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03552912 0,05846995 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03552912 0,05842998 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03552912 0,05839007 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03552912 0,05835022 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03552912 0,05831041 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03552912 0,05827067 ! defense response to virus GO:0051607 37 16 0,000 0,03552912 0,05823097 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03770792 0,06175988 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03770792 0,06171786 ! metencephalon development GO:0022037 30 17 0,000 0,03770792 0,06167591 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03770792 0,06163401 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03770792 0,06159216 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03770792 0,06155038 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03770792 0,06150865 ! signal complex assembly GO:0007172 41 17 0,000 0,03770792 0,06146698 ! endothelial cell migration GO:0043542 28 17 0,000 0,03770792 0,06142536 ! inositol metabolic process GO:0006020 28 17 0,000 0,03770792 0,0613838 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03770792 0,0613423 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03770792 0,06130085 ! glial cell development GO:0021782 27 17 0,000 0,03770792 0,06125946 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03770792 0,06121812 ! adult walking behavior GO:0007628 33 17 0,000 0,03770792 0,06117684 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03770792 0,06113562 ! heart looping GO:0001947 30 17 0,000 0,03770792 0,06109445 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03770792 0,06105334 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03770792 0,06101228 ! myoblast differentiation GO:0045445 45 17 0,000 0,03770792 0,06097127 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03770792 0,06093033 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03770792 0,06088943 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03770792 0,0608486 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03770792 0,06080781 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03770792 0,06076708 ! glycine metabolic process GO:0006544 28 17 0,000 0,03770792 0,06072641 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03770792 0,06068579 ! NAD metabolic process GO:0019674 29 17 0,000 0,03770792 0,06064523 ! membrane budding GO:0006900 37 17 0,000 0,03770792 0,06060471 ! DNA integration GO:0015074 29 17 0,000 0,03770792 0,06056426 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03770792 0,06052385 ! regulation of protein binding GO:0043393 33 17 0,000 0,03770792 0,0604835 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03770792 0,06044321 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03770792 0,06040297 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03770792 0,06036278 ! genitalia development GO:0048806 30 17 0,000 0,03770792 0,06032264 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03770792 0,06028256 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03770792 0,06024253 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03770792 0,06020256 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03770792 0,06016264 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03770792 0,06012277 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03770792 0,06008295 ! steroid catabolic process GO:0006706 31 17 0,000 0,03770792 0,06004319 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03770792 0,06000348 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03770792 0,05996382 ! gas transport GO:0015669 25 17 0,000 0,03770792 0,05992421 ! organic cation transport GO:0015695 31 17 0,000 0,03770792 0,05988466 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03770792 0,05984516 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03770792 0,05980571 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03770792 0,05976631 ! microspike assembly GO:0030035 36 17 0,000 0,03770792 0,05972696 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03770792 0,05968767 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03988187 0,0630873 ! neuron maturation GO:0042551 42 18 0,000 0,03988187 0,06304585 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03988187 0,06300445 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03988187 0,06296311 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03988187 0,06292182 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03988187 0,06288059 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03988187 0,06283941 ! memory GO:0007613 31 18 0,000 0,03988187 0,06279828 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03988187 0,06275721 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03988187 0,06271619 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03988187 0,06267523 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03988187 0,06263432 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03988187 0,06259346 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03988187 0,06255266 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03988187 0,06251191 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03988187 0,06247121 ! response to retinoic acid GO:0032526 26 18 0,000 0,03988187 0,06243056 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03988187 0,06238997 ! response to fungus GO:0009620 21 18 0,000 0,03988187 0,06234943 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03988187 0,06230895 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03988187 0,06226851 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03988187 0,06222813 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03988187 0,0621878 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03988187 0,06214752 ! vitamin transport GO:0051180 27 18 0,000 0,03988187 0,0621073 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03988187 0,06206713 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03988187 0,06202701 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03988187 0,06198694 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03988187 0,06194692 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03988187 0,06190695 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03988187 0,06186704 ! nerve development GO:0021675 28 18 0,000 0,03988187 0,06182718 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03988187 0,06178737 ! protein secretion GO:0009306 39 19 0,000 0,04205098 0,06510596 ! positive regulation of translation GO:0045727 30 19 0,000 0,04205098 0,06506409 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04205098 0,06502227 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04205098 0,06498051 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04205098 0,0649388 ! skin development GO:0043588 36 19 0,000 0,04205098 0,06489715 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04205098 0,06485555 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04205098 0,064814 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04205098 0,06477251 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04205098 0,06473107 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04205098 0,06468968 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04205098 0,06464834 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04205098 0,06460706 ! pigmentation during development GO:0048066 41 19 0,000 0,04205098 0,06456583 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04205098 0,06452465 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04205098 0,06448353 ! heme metabolic process GO:0042168 36 19 0,000 0,04205098 0,06444246 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04205098 0,06440144 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04205098 0,06436047 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04205098 0,06431955 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04205098 0,06427869 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04205098 0,06423788 ! peptide cross-linking GO:0018149 37 19 0,000 0,04205098 0,06419712 ! heart process GO:0003015 30 19 0,000 0,04205098 0,06415641 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04205098 0,06411575 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04205098 0,06407515 ! visual learning GO:0008542 36 19 0,000 0,04205098 0,06403459 ! cellular pigmentation GO:0033059 36 19 0,000 0,04205098 0,06399409 ! G1 phase GO:0051318 40 19 0,000 0,04205098 0,06395364 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04205098 0,06391324 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04205098 0,06387289 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04205098 0,06383259 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04205098 0,06379234 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04205098 0,06375215 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04205098 0,063712 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04205098 0,0636719 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04205098 0,06363186 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04205098 0,06359186 ! cilium assembly GO:0042384 37 19 0,000 0,04205098 0,06355192 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04205098 0,06351203 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04421526 0,06673897 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04421526 0,06669713 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04421526 0,06665534 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04421526 0,0666136 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04421526 0,06657191 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04421526 0,06653028 ! response to vitamin GO:0033273 31 20 0,000 0,04421526 0,0664887 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04421526 0,06644717 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04421526 0,06640569 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04421526 0,06636426 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04421526 0,06632289 ! response to alkaloid GO:0043279 38 20 0,000 0,04421526 0,06628157 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04421526 0,0662403 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04421526 0,06619908 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04421526 0,06615791 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04421526 0,06611679 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04421526 0,06607572 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04421526 0,06603471 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04421526 0,06599374 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04421526 0,06595283 ! body fluid secretion GO:0007589 31 20 0,000 0,04421526 0,06591197 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04421526 0,06587116 ! peptide secretion GO:0002790 35 20 0,000 0,04421526 0,06583039 ! stem cell differentiation GO:0048863 53 20 0,000 0,04421526 0,06578968 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04421526 0,06574902 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04421526 0,06570841 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04421526 0,06566785 ! sensory perception of pain GO:0019233 30 20 0,000 0,04421526 0,06562734 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04421526 0,06558688 ! diencephalon development GO:0021536 34 20 0,000 0,04421526 0,06554647 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04421526 0,06550611 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04421526 0,06546579 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04421526 0,06542553 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04421526 0,06538532 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04421526 0,06534516 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04421526 0,06530504 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04421526 0,06526498 ! regulation of glucose import GO:0046324 29 20 0,000 0,04421526 0,06522496 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04421526 0,065185 ! actin filament-based movement GO:0030048 43 20 0,000 0,04421526 0,06514508 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04421526 0,06510521 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04421526 0,06506539 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04421526 0,06502562 ! negative regulation of translation GO:0017148 29 20 0,000 0,04421526 0,0649859 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04421526 0,06494622 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04421526 0,0649066 ! regulation of cell killing GO:0031341 42 21 0,000 0,04637472 0,06803511 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04637472 0,06799365 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04637472 0,06795224 ! hormone secretion GO:0046879 38 21 0,000 0,04637472 0,06791089 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04637472 0,06786958 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04637472 0,06782832 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04637472 0,06778711 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04637472 0,06774595 ! axis specification GO:0009798 38 21 0,000 0,04637472 0,06770485 ! ovarian follicle development GO:0001541 35 21 0,000 0,04637472 0,06766379 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04637472 0,06762278 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04637472 0,06758182 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04637472 0,06754091 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04637472 0,06750005 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04637472 0,06745924 ! cell aging GO:0007569 44 21 0,000 0,04637472 0,06741848 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04637472 0,06737777 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04637472 0,06733711 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04637472 0,06729649 ! cytolysis GO:0019835 24 21 0,000 0,04637472 0,06725593 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04637472 0,06721541 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,04637472 0,06717495 ! oogenesis GO:0048477 36 21 0,000 0,04637472 0,06713453 ! DNA modification GO:0006304 34 21 0,000 0,04637472 0,06709416 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04637472 0,06705384 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04637472 0,06701356 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04637472 0,06697334 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04637472 0,06693316 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04637472 0,06689304 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04637472 0,06685296 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04637472 0,06681293 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04637472 0,06677294 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04637472 0,06673301 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04637472 0,06669312 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04637472 0,06665328 ! collagen catabolic process GO:0030574 28 21 0,000 0,04637472 0,06661348 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04637472 0,06657374 ! gut development GO:0048565 39 21 0,000 0,04637472 0,06653404 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04852938 0,06958384 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04852938 0,0695424 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04852938 0,069501 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04852938 0,06945966 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04852938 0,06941836 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04852938 0,06937712 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04852938 0,06933592 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04852938 0,06929477 ! regeneration GO:0031099 41 22 0,000 0,04852938 0,06925367 ! keratinization GO:0031424 28 22 0,000 0,04852938 0,06921262 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04852938 0,06917162 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04852938 0,06913066 ! sensory perception of taste GO:0050909 28 22 0,000 0,04852938 0,06908976 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04852938 0,0690489 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04852938 0,06900809 ! vacuolar transport GO:0007034 36 22 0,000 0,04852938 0,06896733 ! lysosome organization GO:0007040 41 22 0,000 0,04852938 0,06892662 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04852938 0,06888595 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04852938 0,06884533 ! fucose metabolic process GO:0006004 39 22 0,000 0,04852938 0,06880477 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04852938 0,06876424 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04852938 0,06872377 ! ureteric bud development GO:0001657 43 22 0,000 0,04852938 0,06868334 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04852938 0,06864297 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04852938 0,06860264 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04852938 0,06856235 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04852938 0,06852212 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04852938 0,06848193 ! sarcomere organization GO:0045214 30 22 0,000 0,04852938 0,06844179 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04852938 0,06840169 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04852938 0,06836164 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04852938 0,06832164 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04852938 0,06828169 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04852938 0,06824178 ! protein stabilization GO:0050821 39 22 0,000 0,04852938 0,06820192 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,05067924 0,0711817 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05067924 0,07114017 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,05067924 0,07109869 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05067924 0,07105725 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05067924 0,07101587 ! gluconeogenesis GO:0006094 33 23 0,000 0,05067924 0,07097453 ! viral genome replication GO:0019079 41 23 0,000 0,05067924 0,07093324 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05067924 0,070892 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05067924 0,07085081 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05067924 0,07080967 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05067924 0,07076857 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05067924 0,07072752 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05067924 0,07068652 ! visual behavior GO:0007632 42 23 0,000 0,05067924 0,07064557 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,05067924 0,07060466 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05067924 0,0705638 ! response to ethanol GO:0045471 46 23 0,000 0,05067924 0,07052299 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05067924 0,07048222 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05067924 0,07044151 ! peroxisome organization GO:0007031 37 23 0,000 0,05067924 0,07040084 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05067924 0,07036021 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05067924 0,07031963 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05067924 0,0702791 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05067924 0,07023862 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,05067924 0,07019818 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,05067924 0,07015779 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05067924 0,07011745 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05067924 0,07007715 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05067924 0,0700369 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05067924 0,0699967 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05067924 0,06995654 ! fatty acid transport GO:0015908 44 23 0,000 0,05067924 0,06991643 ! platelet activation GO:0030168 37 23 0,000 0,05067924 0,06987636 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05067924 0,06983634 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05067924 0,06979636 ! hormone transport GO:0009914 40 23 0,000 0,05067924 0,06975643 ! cell-cell recognition GO:0009988 25 23 0,000 0,05067924 0,06971655 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05067924 0,06967671 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05067924 0,06963692 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05067924 0,06959717 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05067924 0,06955747 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05282431 0,07246026 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05282431 0,07241897 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05282431 0,07237773 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05282431 0,07233653 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05282431 0,07229539 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05282431 0,07225429 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05282431 0,07221323 ! vesicle docking GO:0048278 47 24 0,000 0,05282431 0,07217223 ! spinal cord development GO:0021510 47 24 0,000 0,05282431 0,07213127 ! vacuole organization GO:0007033 43 24 0,000 0,05282431 0,07209035 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05282431 0,07204948 ! digestive system process GO:0022600 39 24 0,000 0,05282431 0,07200866 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05282431 0,07196789 ! regulation of behavior GO:0050795 43 24 0,000 0,05282431 0,07192716 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05282431 0,07188648 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05282431 0,07184584 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05282431 0,07180525 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05282431 0,0717647 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05282431 0,07172421 ! membrane depolarization GO:0051899 39 24 0,000 0,05282431 0,07168375 ! pentose metabolic process GO:0019321 35 24 0,000 0,05282431 0,07164334 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05282431 0,07160298 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05282431 0,07156266 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05282431 0,07152239 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05282431 0,07148217 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05282431 0,07144199 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05282431 0,07140185 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05282431 0,07136176 ! regulation of amine transport GO:0051952 40 24 0,000 0,05282431 0,07132171 ! protein tetramerization GO:0051262 52 24 0,000 0,05282431 0,07128171 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05496461 0,07412828 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,05496461 0,07408675 ! myelination GO:0042552 45 25 0,000 0,05496461 0,07404527 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05496461 0,07400383 ! phototransduction GO:0007602 33 25 0,000 0,05496461 0,07396244 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05496461 0,0739211 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,05496461 0,0738798 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,05496461 0,07383855 ! sperm motility GO:0030317 31 25 0,000 0,05496461 0,07379735 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05496461 0,07375619 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05496461 0,07371508 ! receptor metabolic process GO:0043112 46 25 0,000 0,05496461 0,07367401 ! chromosome condensation GO:0030261 45 25 0,000 0,05496461 0,07363299 ! response to starvation GO:0042594 42 25 0,000 0,05496461 0,07359201 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05496461 0,07355108 ! neural crest cell development GO:0014032 54 25 0,000 0,05496461 0,0735102 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 0,000 0,05496461 0,07346936 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05496461 0,07342856 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05496461 0,07338782 ! interaction with host GO:0051701 62 25 0,000 0,05496461 0,07334711 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05496461 0,07330646 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05496461 0,07326584 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,05496461 0,07322527 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05496461 0,07318475 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05496461 0,07314427 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05496461 0,07310384 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05496461 0,07306345 ! telomere organization GO:0032200 43 25 0,000 0,05496461 0,07302311 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05496461 0,07298281 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05496461 0,07294255 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05710014 0,0757348 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05710014 0,07569308 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05710014 0,07565139 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05710014 0,07560976 ! initiation of viral infection GO:0019059 57 26 0,000 0,05710014 0,07556817 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05710014 0,07552663 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05710014 0,07548513 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05710014 0,07544368 ! molting cycle process GO:0022404 50 26 0,000 0,05710014 0,07540227 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05710014 0,07536091 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05710014 0,07531959 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05710014 0,07527832 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05710014 0,07523709 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,05710014 0,07519591 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,05710014 0,07515478 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05710014 0,07511369 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,05710014 0,07507264 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05710014 0,07503164 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05710014 0,07499068 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05710014 0,07494977 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05710014 0,07490891 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05710014 0,07486808 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05710014 0,07482731 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05710014 0,07478657 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05710014 0,07474588 ! blastocyst development GO:0001824 49 26 0,000 0,05710014 0,07470524 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05710014 0,07466464 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05710014 0,07462408 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05710014 0,07458357 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,05923091 0,07732479 ! neuron fate commitment GO:0048663 48 27 0,000 0,05923091 0,07728285 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05923091 0,07724097 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05923091 0,07719912 ! iron ion transport GO:0006826 59 27 0,000 0,05923091 0,07715733 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05923091 0,07711557 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05923091 0,07707387 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! fat cell differentiation GO:0045444 50 27 0,000 0,05923091 0,07703221 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05923091 0,07699059 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,05923091 0,07694902 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05923091 0,07690749 ! autophagy GO:0006914 41 27 0,000 0,05923091 0,07686601 ! male gonad development GO:0008584 44 27 0,000 0,05923091 0,07682457 ! response to toxin GO:0009636 47 27 0,000 0,05923091 0,07678318 ! primary neural tube formation GO:0014020 51 27 0,000 0,05923091 0,07674183 ! base-excision repair GO:0006284 41 27 0,000 0,05923091 0,07670053 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05923091 0,07665927 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05923091 0,07661805 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05923091 0,07657688 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05923091 0,07653576 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05923091 0,07649468 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05923091 0,07645364 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05923091 0,07641264 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06135695 0,07911298 ! circadian rhythm GO:0007623 50 28 0,000 0,06135695 0,0790706 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06135695 0,07902827 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06135695 0,07898599 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06135695 0,07894375 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06135695 0,07890156 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06135695 0,07885941 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06135695 0,07881731 ! synaptogenesis GO:0007416 42 28 0,000 0,06135695 0,07877525 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,06135695 0,07873323 ! lipid oxidation GO:0034440 43 28 0,000 0,06135695 0,07869127 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06135695 0,07864934 ! translational initiation GO:0006413 65 29 0,000 0,06347824 0,08132516 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06347824 0,08128188 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06347824 0,08123865 ! regulation of pH GO:0006885 43 29 0,000 0,06347824 0,08119546 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06347824 0,08115231 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06347824 0,08110922 ! catechol metabolic process GO:0009712 54 29 0,000 0,06347824 0,08106617 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06347824 0,08102316 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06347824 0,0809802 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06347824 0,08093728 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06347824 0,08089442 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06347824 0,08085159 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06347824 0,08080881 ! cell fate determination GO:0001709 60 29 0,000 0,06347824 0,08076608 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06347824 0,08072339 ! detection of light stimulus GO:0009583 38 29 0,000 0,06347824 0,08068075 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,06347824 0,08063815 ! tissue homeostasis GO:0001894 48 29 0,000 0,06347824 0,0805956 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,06347824 0,08055309 ! phenol metabolic process GO:0018958 55 30 0,000 0,06559482 0,08319512 ! zinc ion transport GO:0006829 45 30 0,000 0,06559482 0,08315128 ! membrane docking GO:0022406 61 30 0,000 0,06559482 0,0831075 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06559482 0,08306375 ! cell junction assembly GO:0034329 78 30 0,000 0,06559482 0,08302006 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06559482 0,08297641 ! acute-phase response GO:0006953 49 30 0,000 0,06559482 0,08293281 ! myofibril assembly GO:0030239 47 30 0,000 0,06559482 0,08288925 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,06559482 0,08284574 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06559482 0,08280227 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06559482 0,08275885 ! phospholipid transport GO:0015914 51 30 0,000 0,06559482 0,08271548 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06559482 0,08267215 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06559482 0,08262887 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06559482 0,08258563 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06559482 0,08254243 ! eye morphogenesis GO:0048592 60 30 0,000 0,06559482 0,08249929 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06559482 0,08245618 ! response to heat GO:0009408 50 30 0,000 0,06559482 0,08241312 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06770668 0,08502206 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06770668 0,08497771 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06770668 0,0849334 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06770668 0,08488915 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06770668 0,08484493 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06770668 0,08480077 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06770668 0,08475664 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06770668 0,08471257 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06770668 0,08466854 ! ovulation cycle process GO:0022602 49 31 0,000 0,06770668 0,08462456 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06770668 0,08458062 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06770668 0,08453673 ! peptide transport GO:0015833 55 31 0,000 0,06770668 0,08449288 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06770668 0,08444908 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06770668 0,08440532 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06770668 0,08436161 ! mesoderm formation GO:0001707 69 31 0,000 0,06770668 0,08431795 ! natural killer cell activation GO:0030101 45 31 0,000 0,06770668 0,08427432 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06770668 0,08423075 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06770668 0,08418722 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06770668 0,08414373 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06770668 0,08410029 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06770668 0,0840569 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06981384 0,08662821 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06981384 0,08658355 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06981384 0,08653894 ! cholesterol transport GO:0030301 56 32 0,000 0,06981384 0,08649438 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06981384 0,08644987 ! spliceosome assembly GO:0000245 67 32 0,000 0,06981384 0,0864054 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06981384 0,08636097 ! metanephros development GO:0001656 74 32 0,000 0,06981384 0,08631659 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06981384 0,08627226 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06981384 0,08622797 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06981384 0,08618373 ! muscle cell development GO:0055001 49 32 0,000 0,06981384 0,08613953 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06981384 0,08609538 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06981384 0,08605128 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06981384 0,08600722 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,06981384 0,0859632 ! ovulation cycle GO:0042698 51 32 0,000 0,06981384 0,08591923 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06981384 0,0858753 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06981384 0,08583142 ! hindbrain development GO:0030902 61 32 0,000 0,06981384 0,08578758 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06981384 0,08574379 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06981384 0,08570005 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,06981384 0,08565634 ! gene silencing GO:0016458 65 32 0,000 0,06981384 0,08561269 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0719163 0,08814601 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0719163 0,08810113 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0719163 0,0880563 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0719163 0,08801151 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0719163 0,08796676 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0719163 0,08792206 ! sterol transport GO:0015918 57 33 0,000 0,0719163 0,08787741 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0719163 0,0878328 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0719163 0,08778824 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0719163 0,08774372 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0719163 0,08769925 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07401408 0,0902117 ! glial cell differentiation GO:0010001 63 34 0,000 0,07401408 0,09016602 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07401408 0,09012039 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07401408 0,0900748 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07401408 0,09002927 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07401408 0,08998377 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07401408 0,08993833 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07401408 0,08989293 ! mismatch repair GO:0006298 46 34 0,000 0,07401408 0,08984757 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07401408 0,08980226 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07401408 0,089757 ! placenta development GO:0001890 53 34 0,000 0,07401408 0,08971178 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,07401408 0,08966661 ! regulation of muscle development GO:0048634 70 35 0,000 0,07610719 0,09215597 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07610719 0,09210961 ! negative regulation of secretion GO:0051048 63 35 0,000 0,07610719 0,0920633 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,07610719 0,09201704 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,07610719 0,09197082 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07610719 0,09192465 ! odontogenesis GO:0042476 66 35 0,000 0,07610719 0,09187853 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07610719 0,09183245 ! female gonad development GO:0008585 58 35 0,000 0,07610719 0,09178642 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,07610719 0,09174044 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,07610719 0,0916945 ! cytokine production GO:0001816 59 35 0,000 0,07610719 0,0916486 ! neural tube formation GO:0001841 67 35 0,000 0,07610719 0,09160276 ! vesicle localization GO:0051648 64 35 0,000 0,07610719 0,09155696 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07819564 0,09402235 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07819564 0,09397538 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07819564 0,09392847 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07819564 0,0938816 ! cell junction organization GO:0034330 86 36 0,000 0,07819564 0,09383477 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07819564 0,093788 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07819564 0,09374126 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07819564 0,09369458 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07819564 0,09364794 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07819564 0,09360135 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,07819564 0,09355481 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07819564 0,09350831 ! embryonic organ development GO:0048568 57 36 0,000 0,07819564 0,09346186 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07819564 0,09341545 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07819564 0,09336909 ! meiosis I GO:0007127 65 37 0,000 0,08027944 0,09580969 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,08027944 0,09576219 ! sister chromatid segregation GO:0000819 58 37 0,000 0,08027944 0,09571473 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08027944 0,09566733 ! organic anion transport GO:0015711 68 37 0,000 0,08027944 0,09561997 ! tissue remodeling GO:0048771 76 37 0,000 0,08027944 0,09557265 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,08027944 0,09552539 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,08027944 0,09547817 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,08027944 0,09543099 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,08027944 0,09538387 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08027944 0,09533679 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,08027944 0,09528976 ! pigment metabolic process GO:0042440 80 37 0,000 0,08027944 0,09524277 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,0823586 0,0976613 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,0823586 0,09761319 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,0823586 0,09756513 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,0823586 0,09751712 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,0823586 0,09746915 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,0823586 0,09742123 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,0823586 0,09737336 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,0823586 0,09732553 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,0823586 0,09727775 ! lipid homeostasis GO:0055088 67 38 0,000 0,0823586 0,09723002 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,0823586 0,09718234 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,0823586 0,0971347 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,0823586 0,09708711 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,0823586 0,09703956 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,0823586 0,09699206 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,0823586 0,09694461 ! mRNA catabolic process GO:0006402 71 39 0,000 0,08443312 0,09933794 ! mammary gland development GO:0030879 86 39 0,000 0,08443312 0,09928939 ! learning GO:0007612 77 39 0,000 0,08443312 0,09924088 ! ear morphogenesis GO:0042471 60 39 0,000 0,08443312 0,09919243 ! organic ether metabolic process GO:0018904 55 39 0,000 0,08443312 0,09914402 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,08443312 0,09909565 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08443312 0,09904734 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,08443312 0,09899907 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,08443312 0,09895085 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08443312 0,09890267 ! RNA modification GO:0009451 57 39 0,000 0,08443312 0,09885454 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08443312 0,09880646 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08650302 0,10117952 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08650302 0,10113036 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08650302 0,10108124 ! feeding behavior GO:0007631 59 40 0,000 0,08650302 0,10103217 ! negative regulation of binding GO:0051100 72 40 0,000 0,08650302 0,10098315 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08650302 0,10093418 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08650302 0,10088525 ! maintenance of protein location GO:0045185 91 40 0,000 0,08650302 0,10083637 ! cytokinesis GO:0000910 72 40 0,000 0,08650302 0,10078754 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08856832 0,10314393 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08856832 0,10309403 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08856832 0,10304418 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08856832 0,10299438 ! gliogenesis GO:0042063 88 41 0,000 0,08856832 0,10294462 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08856832 0,10289491 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08856832 0,10284525 ! T cell differentiation GO:0030217 81 41 0,000 0,08856832 0,10279564 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08856832 0,10274608 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,08856832 0,10269656 ! female gamete generation GO:0007292 61 41 0,000 0,08856832 0,10264709 ! polyol metabolic process GO:0019751 66 41 0,000 0,08856832 0,10259767 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08856832 0,1025483 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,09062901 0,10488379 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,09062901 0,10483336 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,09062901 0,10478298 ! regulation of protein secretion GO:0050708 71 42 0,000 0,09062901 0,10473266 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,09062901 0,10468238 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,09268511 0,10700594 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09268511 0,10695461 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09268511 0,10690334 ! glucose transport GO:0015758 65 43 0,000 0,09268511 0,10685212 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09268511 0,10680094 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09268511 0,10674982 ! neural tube development GO:0021915 77 43 0,000 0,09268511 0,10669874 ! striated muscle contraction GO:0006941 77 43 0,000 0,09268511 0,10664771 ! phagocytosis GO:0006909 90 43 0,000 0,09268511 0,10659673 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09268511 0,1065458 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09473663 0,10885211 ! hexose transport GO:0008645 67 44 0,000 0,09473663 0,10880016 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09473663 0,10874825 ! male sex differentiation GO:0046661 76 44 0,000 0,09473663 0,10869639 ! biopolymer methylation GO:0043414 84 44 0,000 0,09473663 0,10864458 ! B cell differentiation GO:0030183 107 44 0,000 0,09473663 0,10859282 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09473663 0,10854111 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09473663 0,10848945 ! developmental growth GO:0048589 82 44 0,000 0,09473663 0,10843783 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09473663 0,10838627 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09678358 0,11067552 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,09678358 0,11062294 ! leukocyte migration GO:0050900 68 45 0,000 0,09678358 0,11057041 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09678358 0,11051793 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,09678358 0,11046551 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,09678358 0,11041313 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09678358 0,1103608 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09678358 0,11030852 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09678358 0,11025629 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09678358 0,11020411 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09678358 0,11015198 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09882597 0,1124233 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,09882597 0,11237017 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09882597 0,11231709 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,09882597 0,11226406 ! pigmentation GO:0043473 100 46 0,000 0,09882597 0,11221108 ! positive regulation of defense response GO:0031349 76 47 0,000 0,1008638 0,1144709 ! response to calcium ion GO:0051592 81 47 0,000 0,1008638 0,11441693 ! endosome transport GO:0016197 108 47 0,000 0,1008638 0,11436301 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1008638 0,11430914 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,1008638 0,11425533 ! JNK cascade GO:0007254 91 47 0,000 0,1008638 0,11420156 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,1008638 0,11414784 ! methylation GO:0032259 90 47 0,000 0,1008638 0,11409418 ! mitochondrial transport GO:0006839 82 48 0,000 0,1028971 0,11633949 ! Notch signaling pathway GO:0007219 96 48 0,000 0,1028971 0,11628484 ! cellular component disassembly GO:0022411 86 48 0,000 0,1028971 0,11623025 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,1028971 0,1161757 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,1028971 0,11612121 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,1028971 0,11606677 ! activation of caspase activity GO:0006919 84 48 0,000 0,1028971 0,11601238 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,1028971 0,11595805 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,1028971 0,11590376 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,1028971 0,11584952 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,1028971 0,11579534 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10492587 0,11802321 ! regulation of action potential GO:0001508 95 49 0,000 0,10492587 0,11796806 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10492587 0,11791296 ! regulation of ion transport GO:0043269 77 49 0,000 0,10492587 0,11785791 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10492587 0,11780291 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10492587 0,11774797 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10492587 0,11769307 ! endocrine system development GO:0035270 104 49 0,000 0,10492587 0,11763823 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10492587 0,11758344 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10492587 0,1175287 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10492587 0,11747401 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10492587 0,11741937 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,10695012 0,119629 ! regulation of ossification GO:0030278 117 50 0,000 0,10695012 0,11957341 ! inner ear development GO:0048839 79 50 0,000 0,10695012 0,11951787 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10695012 0,11946239 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,10695012 0,11940695 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,10695012 0,11935157 ! viral infectious cycle GO:0019058 99 51 0,000 0,10896985 0,12154912 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10896985 0,1214928 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10896985 0,12143653 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10896985 0,12138031 ! excretion GO:0007588 83 51 0,000 0,10896985 0,12132414 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10896985 0,12126802 ! chromatin remodeling GO:0006338 109 51 0,000 0,10896985 0,12121196 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10896985 0,12115594 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10896985 0,12109998 ! vesicle organization GO:0016050 107 51 0,000 0,10896985 0,12104407 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,10896985 0,12098821 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,10896985 0,12093241 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10896985 0,12087665 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,11098509 0,12305535 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,11098509 0,12299867 ! membrane fusion GO:0006944 110 52 0,000 0,11098509 0,12294204 ! positive regulation of growth GO:0045927 90 52 0,000 0,11098509 0,12288547 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,11098509 0,12282894 ! amino acid activation GO:0043038 92 52 0,000 0,11098509 0,12277247 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,11098509 0,12271605 ! synapse organization GO:0050808 85 52 0,000 0,11098509 0,12265968 ! RNA catabolic process GO:0006401 93 53 0,000 0,11299583 0,12482459 ! regulation of translational initiation GO:0006446 82 53 0,000 0,11299583 0,12476731 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,11299583 0,12471008 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,11299583 0,1246529 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,11299583 0,12459577 ! cell maturation GO:0048469 100 53 0,000 0,11299583 0,12453869 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,11299583 0,12448167 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11500209 0,12663388 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11500209 0,12657595 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11500209 0,12651808 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11500209 0,12646025 ! chloride transport GO:0006821 90 55 0,000 0,11700388 0,12860272 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,11700388 0,12854399 GO:0010952|positive regulation of peptidase activity, ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11700388 0,12848532 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11700388 0,12842671 ! gastrulation GO:0007369 112 55 0,000 0,11700388 0,12836815 ! heart morphogenesis GO:0003007 97 55 0,000 0,11700388 0,12830964 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11700388 0,12825118 ! RNA elongation GO:0006354 79 55 0,000 0,11700388 0,12819278 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11700388 0,12813443 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11900121 0,13026248 ! sensory perception of smell GO:0007608 80 56 0,000 0,11900121 0,13020324 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,11900121 0,13014405 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11900121 0,13008493 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,11900121 0,13002585 ! regulation of DNA replication GO:0006275 101 56 0,000 0,11900121 0,12996683 ! proton transport GO:0015992 94 56 0,000 0,11900121 0,12990786 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,11900121 0,12984894 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,12099409 0,13196364 ! muscle fiber development GO:0048747 112 57 0,000 0,12099409 0,13190385 ! maintenance of location GO:0051235 118 57 0,000 0,12099409 0,13184411 ! hydrogen transport GO:0006818 97 58 0,000 0,12298253 0,13395019 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,12298253 0,13388958 ! regulation of endocytosis GO:0030100 91 58 0,000 0,12298253 0,13382902 ! positive regulation of secretion GO:0051047 95 59 0,000 0,12496653 0,13592653 ! regulation of cellular component size GO:0032535 109 59 0,000 0,12496653 0,13586511 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,12496653 0,13580374 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,12496653 0,13574243 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,12496653 0,13568117 ! DNA catabolic process GO:0006308 86 59 0,000 0,12496653 0,13561997 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,12496653 0,13555883 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,12694612 0,13764414 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,12694612 0,13758214 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,12694612 0,1375202 ! regulation of heart contraction GO:0008016 110 60 0,000 0,12694612 0,1374583 ! camera-type eye development GO:0043010 116 60 0,000 0,12694612 0,13739647 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,12694612 0,13733469 ! kidney development GO:0001822 122 60 0,000 0,12694612 0,13727297 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12892128 0,13934619 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,12892128 0,13928362 ! mesoderm development GO:0007498 119 61 0,000 0,12892128 0,1392211 ! tRNA processing GO:0008033 89 61 0,000 0,12892128 0,13915864 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12892128 0,13909624 ! ear development GO:0043583 103 62 0,000 0,13089205 0,14115924 ! viral reproductive process GO:0022415 126 62 0,000 0,13089205 0,141096 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,13089205 0,14103281 ! gonad development GO:0008406 98 62 0,000 0,13089205 0,14096968 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,13089205 0,14090661 ! regulation of mitosis GO:0007088 105 63 0,000 0,13285842 0,14295947 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,13285842 0,14289556 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,13285842 0,14283171 ! detection of external stimulus GO:0009581 91 63 0,000 0,13285842 0,14276792 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,13285842 0,14270418 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13482041 0,14474695 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,13482041 0,14468239 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13482041 0,14461788 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,13482041 0,14455344 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13677803 0,14658705 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13677803 0,14652179 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,13677803 0,14645658 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,13677803 0,14639143 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13873128 0,14841594 ! actin filament organization GO:0007015 148 66 0,000 0,13873128 0,14834998 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,13873128 0,14828408 ! extracellular matrix organization GO:0030198 133 66 0,000 0,13873128 0,14821823 ! secondary metabolic process GO:0019748 116 66 0,000 0,13873128 0,14815244 ! developmental maturation GO:0021700 116 66 0,000 0,13873128 0,14808672 ! cell projection assembly GO:0030031 120 66 0,000 0,13873128 0,14802105 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,14068018 0,15003391 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,14068018 0,14996744 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,14068018 0,14990102 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,14068018 0,14983466 ! activation of MAPK activity GO:0000187 115 67 0,000 0,14068018 0,14976836 ! chromosome segregation GO:0007059 113 67 0,000 0,14068018 0,14970212 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,14068018 0,14963594 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,14068018 0,14956982 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,14068018 0,14950376 ! adaptive immune response GO:0002250 119 67 0,000 0,14068018 0,14943775 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,14068018 0,1493718 ! amino acid transport GO:0006865 125 68 0,000 0,14262473 0,15136969 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,14262473 0,15130295 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,14262473 0,15123627 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,14262473 0,15116964 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,14262473 0,15110308 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,14262473 0,15103657 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,14262473 0,15097012 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,14456494 0,15295657 ! negative regulation of cell size GO:0045792 134 69 0,000 0,14456494 0,15288934 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14456494 0,15282217 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14456494 0,15275505 ! urogenital system development GO:0001655 137 69 0,000 0,14456494 0,15268799 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14456494 0,152621 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14456494 0,15255406 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14456494 0,15248718 ! appendage morphogenesis GO:0035107 135 70 0,000 0,14650083 0,15446144 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,1484324 0,15642942 ! reproductive structure development GO:0048608 113 71 0,000 0,1484324 0,15636093 ! appendage development GO:0048736 136 71 0,000 0,1484324 0,1562925 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,1484324 0,15622413 ! B cell activation GO:0042113 160 71 0,000 0,1484324 0,15615582 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,1484324 0,15608757 ! regulation of immune effector process GO:0002697 137 71 0,000 0,1484324 0,15601938 ! acute inflammatory response GO:0002526 113 72 0,000 0,15035967 0,15797614 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,15035967 0,15790718 ! carbohydrate transport GO:0008643 110 72 0,000 0,15035967 0,15783829 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,15035967 0,15776945 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,15035967 0,15770068 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,15035967 0,15763196 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,15228263 0,1595784 ! axon guidance GO:0007411 139 73 0,000 0,15228263 0,15950893 ! fertilization GO:0009566 90 73 0,000 0,15228263 0,15943952 ! transition metal ion transport GO:0000041 126 74 0,000 0,15420131 0,16137815 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15420131 0,16130798 ! meiosis GO:0007126 121 74 0,000 0,15420131 0,16123788 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,15420131 0,16116784 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15420131 0,16109785 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,15420131 0,16102793 ! eye development GO:0001654 143 74 0,000 0,15420131 0,16095807 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,15611571 0,16288569 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,15611571 0,16281509 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,15611571 0,16274454 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,15611571 0,16267406 ! meiotic cell cycle GO:0051321 122 75 0,000 0,15611571 0,16260364 ! rhythmic process GO:0048511 128 75 0,000 0,15611571 0,16253328 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,15611571 0,16246298 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,15802584 0,16437967 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,15802584 0,16430863 ! defense response to bacterium GO:0042742 89 76 0,000 0,15802584 0,16423766 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,15802584 0,16416674 ! regulation of catabolic process GO:0009894 161 76 0,000 0,15802584 0,16409589 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15993171 0,16600332 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15993171 0,16593174 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15993171 0,16586022 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,15993171 0,16578875 ! blood coagulation GO:0007596 146 78 0,000 0,16183333 0,16768777 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,16183333 0,16761558 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,16183333 0,16754346 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,16373071 0,16943488 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,16373071 0,16936203 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,16373071 0,16928925 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,16373071 0,16921653 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,16373071 0,16914388 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,16562385 0,17102618 ! response to metal ion GO:0010038 140 80 0,000 0,16562385 0,17095281 ! muscle cell differentiation GO:0042692 159 80 0,000 0,16562385 0,1708795 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,16562385 0,17080626 ! protein import into nucleus GO:0006606 158 80 0,000 0,16562385 0,17073307 ! inorganic anion transport GO:0015698 138 80 0,000 0,16562385 0,17065995 ! T cell activation GO:0042110 168 81 0,000 0,16751278 0,17253242 ! digestion GO:0007586 112 81 0,000 0,16751278 0,1724586 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,16751278 0,17238483 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16751278 0,17231113 ! nuclear import GO:0051170 161 81 0,000 0,16751278 0,1722375 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,16751278 0,17216392 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,16939749 0,17402662 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,16939749 0,17395235 ! response to drug GO:0042493 143 82 0,000 0,16939749 0,17387814 ! response to nutrient GO:0007584 125 82 0,000 0,16939749 0,17380399 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16939749 0,1737299 ! regulation of lyase activity GO:0051339 160 83 0,000 0,17127799 0,17558366 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,1731543 0,17743154 ! hemostasis GO:0007599 158 84 0,000 0,1731543 0,177356 ! negative regulation of transport GO:0051051 153 84 0,000 0,1731543 0,17728053 ! negative regulation of growth GO:0045926 155 84 0,000 0,1731543 0,17720513 ! regulation of ligase activity GO:0051340 142 84 0,000 0,1731543 0,17712978 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,1731543 0,17705451 ! response to unfolded protein GO:0006986 131 85 0,000 0,17502643 0,17889277 ! nucleosome assembly GO:0006334 122 85 0,000 0,17502643 0,17881681 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17502643 0,17874091 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,17502643 0,17866508 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,17689437 0,18049528 ! response to inorganic substance GO:0010035 153 86 0,000 0,17689437 0,18041876 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,17689437 0,18034232 ! chromatin assembly GO:0031497 124 86 0,000 0,17689437 0,18026593 ! tube morphogenesis GO:0035239 176 86 0,000 0,17689437 0,18018961 ! amine transport GO:0015837 155 86 0,000 0,17689437 0,18011336 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,17875815 0,18193406 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,17875815 0,18185713 ! protein localization in nucleus GO:0034504 176 87 0,000 0,17875815 0,18178027 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,18061778 0,18359373 ! gland development GO:0048732 206 88 0,000 0,18061778 0,1835162 ! regulation of neurological system process GO:0031644 148 88 0,000 0,18061778 0,18343874 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,18061778 0,18336134 ! cellular defense response GO:0006968 114 89 0,000 0,18247325 0,18516687 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,18247325 0,1850888 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,18247325 0,1850108 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,18432458 0,18680916 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,18432458 0,1867305 ! sex differentiation GO:0007548 145 90 0,000 0,18432458 0,18665191 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,18432458 0,18657339 ! sterol metabolic process GO:0016125 152 91 0,000 0,18617178 0,18836388 ! response to protein stimulus GO:0051789 149 91 0,000 0,18617178 0,1882847 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,18617178 0,18820559 ! regulation of defense response GO:0031347 149 92 0,000 0,18801486 0,18998898 ! nucleosome organization GO:0034728 138 92 0,000 0,18801486 0,18990922 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,18801486 0,18982953 ! vitamin metabolic process GO:0006766 139 92 0,000 0,18801486 0,1897499 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,18985383 0,1915255 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,18985383 0,19144523 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,18985383 0,19136503 ! regulation of membrane potential GO:0042391 164 93 0,000 0,18985383 0,19128489 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,18985383 0,19120482 ! female pregnancy GO:0007565 164 94 0,000 0,19168869 0,19297197 ! transcription initiation GO:0006352 153 94 0,000 0,19168869 0,19289126 ! regulation of T cell activation GO:0050863 158 94 0,000 0,19168869 0,19281062 ! leukocyte differentiation GO:0002521 202 96 0,000 0,19534615 0,19640737 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,19534615 0,19632532 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,19534615 0,19624335 ! positive regulation of immune response GO:0050778 156 96 0,000 0,19534615 0,19616145 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,19716875 0,19790906 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,19716875 0,19782653 ! protein ubiquitination GO:0016567 217 97 0,000 0,19716875 0,19774407 ! hormone metabolic process GO:0042445 157 97 0,000 0,19716875 0,19766167 ! response to virus GO:0009615 160 98 0,000 0,19898729 0,19940167 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,19898729 0,19931866 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,19898729 0,19923571 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,20080177 0,20096883 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,20080177 0,20088526 ! cell cycle arrest GO:0007050 213 100 0,000 0,2026122 0,2026122