pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1302-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of actin filament polymerization GO:0030838 11 6 4,000 6,968E-11 1,677E-07 ! positive regulation of protein polymerization GO:0032273 25 13 5,000 1,236E-10 1,487E-07 ! positive regulation of protein complex assembly GO:0031334 32 17 5,000 8,72E-10 6,994E-07 ! positive regulation of cytoskeleton organization GO:0051495 48 22 5,000 5,115E-09 3,077E-06 ! positive regulation of organelle organization GO:0010638 100 56 6,000 8,429E-08 4,056E-05 ! negative regulation of endocytosis GO:0045806 11 8 3,000 1,243E-07 4,983E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 3,000 2,225E-07 7,649E-05 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 5,000 1,329E-06 3,996E-04 ! regulation of protein polymerization GO:0032271 103 53 5,000 1,329E-06 3,552E-04 ! regulation of actin filament length GO:0030832 105 56 5,000 1,849E-06 4,448E-04 ! regulation of cellular component size GO:0032535 109 59 5,000 2,524E-06 5,52E-04 ! regulation of protein complex assembly GO:0043254 117 61 5,000 3,076E-06 6,168E-04 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 2,000 5,517E-06 1,021E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 8,085E-06 1,39E-03 ! regulation of actin cytoskeleton organization GO:0032956 149 74 5,000 9,561E-06 1,534E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 2,000 9,607E-06 1,445E-03 ! regulation of actin filament polymerization GO:0030833 87 45 4,000 1,152E-05 1,631E-03 ! regulation of actin filament-based process GO:0032970 152 77 5,000 1,204E-05 1,609E-03 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 3,000 1,208E-05 1,53E-03 ! regulation of Rac protein signal transduction GO:0035020 11 8 2,000 1,53E-05 1,84E-03 ! liver development GO:0001889 53 25 3,000 2,057E-05 2,357E-03 ! ruffle organization GO:0031529 15 9 2,000 2,283E-05 2,497E-03 ! gas homeostasis GO:0033483 16 9 2,000 2,283E-05 2,389E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 2,419E-05 2,425E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 3,000 2,419E-05 2,328E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 3,246E-05 3,004E-03 ! regulation of endocytosis GO:0030100 91 58 4,000 4,032E-05 3,593E-03 ! cortical actin cytoskeleton organization GO:0030866 30 11 2,000 4,442E-05 3,817E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 4,442E-05 3,685E-03 ! positive regulation of catabolic process GO:0009896 64 32 3,000 5,642E-05 4,525E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 5,894E-05 4,575E-03 ! cortical cytoskeleton organization GO:0030865 31 12 2,000 5,894E-05 4,432E-03 ! mRNA polyadenylation GO:0006378 23 12 2,000 5,894E-05 4,297E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 6,498E-05 4,599E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 7,625E-05 5,242E-03 ! mRNA 3'-end processing GO:0031124 24 13 2,000 7,625E-05 5,096E-03 ! RNA polyadenylation GO:0043631 30 14 2,000 9,658E-05 6,28E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 1,01E-04 6,394E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 2,000 1,201E-04 7,412E-03 ! cytokinesis GO:0000910 72 40 3,000 1,376E-04 8,277E-03 ! regulation of vesicle-mediated transport GO:0060627 119 75 4,000 1,388E-04 8,143E-03 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 2,000 1,471E-04 8,429E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 1,778E-04 9,949E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,778E-04 9,723E-03 ! RNA 3'-end processing GO:0031123 34 17 2,000 1,778E-04 9,507E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 2,114E-04 0,01105531 ! positive regulation of proteolysis GO:0045862 31 18 2,000 2,123E-04 0,01087016 ! regulation of JAK-STAT cascade GO:0046425 70 45 3,000 2,187E-04 0,01096057 ! negative regulation of transport GO:0051051 153 84 4,000 2,366E-04 0,01161888 ! response to insulin stimulus GO:0032868 95 46 3,000 2,383E-04 0,01146533 ! response to lipopolysaccharide GO:0032496 30 19 2,000 2,509E-04 0,01183838 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,938E-04 0,01359365 ! endocrine system development GO:0035270 104 49 3,000 3,046E-04 0,0138295 ! positive regulation of growth GO:0045927 90 52 3,000 3,833E-04 0,01707903 ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 3,931E-04 0,01719438 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 4,245E-04 0,01823759 ! positive regulation of glycolysis GO:0045821 14 5 1,000 4,245E-04 0,01791764 ! parathyroid gland development GO:0060017 13 5 1,000 4,245E-04 0,01760871 ! anagen GO:0042640 6 5 1,000 4,245E-04 0,01731026 ! valine metabolic process GO:0006573 10 5 1,000 4,245E-04 0,01702175 ! mRNA transcription GO:0009299 9 5 1,000 4,245E-04 0,01674271 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 4,245E-04 0,01647267 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,245E-04 0,0162112 ! adaptation of signaling pathway GO:0022401 7 5 1,000 4,245E-04 0,0159579 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 4,245E-04 0,01571239 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 4,245E-04 0,01547432 GO:0051489|regulation of filopodium assembly, ! response to food GO:0032094 6 5 1,000 4,245E-04 0,01524336 ! meiotic chromosome segregation GO:0045132 7 5 1,000 4,245E-04 0,0150192 ! positive regulation of chemokine production GO:0032722 8 5 1,000 4,245E-04 0,01480153 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 1,000 4,245E-04 0,01459008 ! regulation of muscle cell apoptosis GO:0010660 8 5 1,000 4,245E-04 0,01438458 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 1,000 4,245E-04 0,0141848 ! response to molecule of bacterial origin GO:0002237 34 23 2,000 4,498E-04 0,01482593 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 5,116E-04 0,01663427 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 5,116E-04 0,01641248 ! vesicle docking GO:0048278 47 24 2,000 5,116E-04 0,01619652 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 5,116E-04 0,01598618 ! positive regulation of cell migration GO:0030335 126 57 3,000 5,452E-04 0,01681632 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 6,34E-04 0,01930786 ! protein refolding GO:0042026 15 6 1,000 6,34E-04 0,01906652 ! embryonic hemopoiesis GO:0035162 14 6 1,000 6,34E-04 0,01883113 ! toxin metabolic process GO:0009404 11 6 1,000 6,34E-04 0,01860148 ! T cell mediated immunity GO:0002456 16 6 1,000 6,34E-04 0,01837736 ! establishment of spindle localization GO:0051293 12 6 1,000 6,34E-04 0,01815859 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,34E-04 0,01794496 GO:0045686|negative regulation of glial cell differentiation, ! interaction with symbiont GO:0051702 13 6 1,000 6,34E-04 0,01773629 ! response to exogenous dsRNA GO:0043330 10 6 1,000 6,34E-04 0,01753243 ! hair follicle maturation GO:0048820 7 6 1,000 6,34E-04 0,0173332 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 1,000 6,34E-04 0,01713844 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! receptor internalization GO:0031623 10 6 1,000 6,34E-04 0,01694801 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 1,000 6,34E-04 0,01676177 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 6,34E-04 0,01657958 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 6,509E-04 0,01683892 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 7,057E-04 0,01806172 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 8,461E-04 0,02142835 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 8,837E-04 0,02214795 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 8,837E-04 0,02191962 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 8,837E-04 0,02169595 ! microtubule nucleation GO:0007020 20 7 1,000 8,837E-04 0,0214768 ! vesicle fusion GO:0006906 17 7 1,000 8,837E-04 0,02126204 ! oxygen homeostasis GO:0032364 12 7 1,000 8,837E-04 0,02105152 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 8,837E-04 0,02084513 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 8,837E-04 0,02064275 ! embryonic heart tube development GO:0035050 10 7 1,000 8,837E-04 0,02044426 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 8,837E-04 0,02024956 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 8,837E-04 0,02005852 ! complement activation, classical pathway GO:0006958 48 29 2,000 9,016E-04 0,02027272 ! actin filament organization GO:0007015 148 66 3,000 9,5E-04 0,0211636 ! membrane docking GO:0022406 61 30 2,000 9,969E-04 0,0220054 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 9,969E-04 0,02180535 ! adaptive immune response GO:0002250 119 67 3,000 1,005E-03 0,02178752 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of T cell proliferation GO:0042102 52 31 2,000 1,098E-03 0,02359633 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 2,000 1,098E-03 0,02338751 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 1,000 1,173E-03 0,02476026 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,173E-03 0,02454495 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 1,173E-03 0,02433336 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 1,000 1,173E-03 0,02412538 ! oligopeptide transport GO:0006857 15 8 1,000 1,173E-03 0,02392093 ! succinate metabolic process GO:0006105 14 8 1,000 1,173E-03 0,02371991 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 1,173E-03 0,02352225 ! hemoglobin metabolic process GO:0020027 13 8 1,000 1,173E-03 0,02332785 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 1,173E-03 0,02313664 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,173E-03 0,02294853 ! response to UV-B GO:0010224 16 8 1,000 1,173E-03 0,02276346 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,173E-03 0,02258136 ! positive regulation of interferon-gamma production GO:0032729 12 8 1,000 1,173E-03 0,02240214 ! regulation of immune response to tumor cell GO:0002837 15 8 1,000 1,173E-03 0,02222574 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,173E-03 0,02205211 ! spindle organization GO:0007051 46 32 2,000 1,206E-03 0,0224972 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,206E-03 0,02232414 ! acute inflammatory response GO:0002526 113 72 3,000 1,315E-03 0,0241551 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 1,32E-03 0,02406807 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 2,000 1,441E-03 0,02607269 ! placenta development GO:0001890 53 34 2,000 1,441E-03 0,02587812 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,441E-03 0,02568643 ! leukocyte mediated immunity GO:0002443 128 74 3,000 1,456E-03 0,02575855 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,502E-03 0,02637554 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,502E-03 0,02618441 ! artery development GO:0060840 24 9 1,000 1,502E-03 0,02599604 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 1,000 1,502E-03 0,02581035 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 1,502E-03 0,0256273 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 1,502E-03 0,02544683 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,502E-03 0,02526888 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,502E-03 0,0250934 GO:0006600|creatine metabolic process, ! regulation of Notch signaling pathway GO:0008593 22 9 1,000 1,502E-03 0,02492034 ! postreplication repair GO:0006301 22 9 1,000 1,502E-03 0,02474965 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,502E-03 0,02458129 ! regulation of catabolic process GO:0009894 161 76 3,000 1,607E-03 0,02612505 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 2,000 1,703E-03 0,02750236 ! regulation of proteolysis GO:0030162 72 36 2,000 1,703E-03 0,02731901 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 2,000 1,703E-03 0,02713809 ! blood coagulation GO:0007596 146 78 3,000 1,769E-03 0,02799512 GO:0050817|coagulation, ! tissue remodeling GO:0048771 76 37 2,000 1,845E-03 0,02900645 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,853E-03 0,02895742 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,869E-03 0,02901474 ! COPI coating of Golgi vesicle GO:0048205 19 10 1,000 1,869E-03 0,02882875 GO:0048200|Golgi transport vesicle coating, ! pathogenesis GO:0009405 13 10 1,000 1,869E-03 0,02864513 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 1,869E-03 0,02846383 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,869E-03 0,02828481 GO:0005978|glycogen biosynthetic process, ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 1,869E-03 0,02810803 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,869E-03 0,02793345 GO:0045685|regulation of glial cell differentiation, ! response to dsRNA GO:0043331 20 10 1,000 1,869E-03 0,02776102 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 1,000 1,869E-03 0,0275907 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,869E-03 0,02742247 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,869E-03 0,02725627 GO:0043470|regulation of carbohydrate catabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 2,000 1,993E-03 0,02888692 GO:0006956|complement activation, ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 1,993E-03 0,02871394 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! thyroid gland development GO:0030878 26 11 1,000 2,275E-03 0,03257697 ! Golgi vesicle budding GO:0048194 22 11 1,000 2,275E-03 0,03238421 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,275E-03 0,03219371 ! melanocyte differentiation GO:0030318 21 11 1,000 2,275E-03 0,03200545 GO:0050931|pigment cell differentiation, ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 2,275E-03 0,03181937 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 2,275E-03 0,03163544 ! neuroblast proliferation GO:0007405 24 11 1,000 2,275E-03 0,03145363 ! thymus development GO:0048538 27 11 1,000 2,275E-03 0,03127389 ! germ cell migration GO:0008354 25 11 1,000 2,275E-03 0,0310962 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 2,275E-03 0,03092052 ! lamellipodium assembly GO:0030032 20 11 1,000 2,275E-03 0,03074681 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 2,000 2,312E-03 0,03107378 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 2,312E-03 0,03090114 ! hemostasis GO:0007599 158 84 3,000 2,32E-03 0,03084493 ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,482E-03 0,032816 ! mitochondrion organization GO:0007005 148 86 3,000 2,528E-03 0,03323638 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 2,66E-03 0,03478838 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,66E-03 0,03460033 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 2,718E-03 0,03515675 ! folic acid and derivative biosynthetic process GO:0009396 21 12 1,000 2,718E-03 0,03496875 ! regulation of cell projection assembly GO:0060491 30 12 1,000 2,718E-03 0,03478274 ! hippocampus development GO:0021766 26 12 1,000 2,718E-03 0,03459871 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,718E-03 0,03441661 ! positive regulation of cell growth GO:0030307 22 12 1,000 2,718E-03 0,03423642 ! drug transport GO:0015893 16 12 1,000 2,718E-03 0,0340581 ! focal adhesion formation GO:0048041 35 12 1,000 2,718E-03 0,03388164 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 1,000 2,718E-03 0,03370699 GO:0002717|positive regulation of natural killer cell mediated immunity, ! synaptic vesicle exocytosis GO:0016079 19 12 1,000 2,718E-03 0,03353413 ! gland morphogenesis GO:0022612 29 12 1,000 2,718E-03 0,03336304 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 2,718E-03 0,03319368 ! T cell homeostasis GO:0043029 25 12 1,000 2,718E-03 0,03302604 ! gland development GO:0048732 206 88 3,000 2,748E-03 0,03322325 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 2,846E-03 0,03424061 ! receptor-mediated endocytosis GO:0006898 88 43 2,000 2,846E-03 0,03407026 ! glucose transport GO:0015758 65 43 2,000 2,846E-03 0,0339016 ! hexose transport GO:0008645 67 44 2,000 3,04E-03 0,03602931 GO:0015749|monosaccharide transport, ! regulation of chemokine production GO:0032642 18 13 1,000 3,198E-03 0,0377193 ! lipid localization GO:0010876 28 13 1,000 3,198E-03 0,0375353 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 3,198E-03 0,03735309 ! organelle fusion GO:0048284 32 13 1,000 3,198E-03 0,03717264 ! pseudouridine synthesis GO:0001522 17 13 1,000 3,198E-03 0,03699393 ! endocrine pancreas development GO:0031018 22 13 1,000 3,198E-03 0,03681692 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,198E-03 0,0366416 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of natural killer cell mediated immunity GO:0002715 27 13 1,000 3,198E-03 0,03646795 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! embryonic placenta development GO:0001892 23 13 1,000 3,198E-03 0,03629593 ! actin filament polymerization GO:0030041 24 13 1,000 3,198E-03 0,03612552 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 3,198E-03 0,03595671 ! glycolysis GO:0006096 65 45 2,000 3,241E-03 0,03627347 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,451E-03 0,03843937 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 3,451E-03 0,03826223 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 3,451E-03 0,03808671 ! JNK cascade GO:0007254 91 47 2,000 3,669E-03 0,04030368 ! protein homooligomerization GO:0051260 76 47 2,000 3,669E-03 0,04012048 ! tRNA modification GO:0006400 20 14 1,000 3,715E-03 0,04044554 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 1,000 3,715E-03 0,04026336 ! palate development GO:0060021 31 14 1,000 3,715E-03 0,0400828 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 3,715E-03 0,03990386 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,715E-03 0,03972651 ! positive regulation of immune response GO:0050778 156 96 3,000 3,759E-03 0,04001616 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,894E-03 0,0412768 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,894E-03 0,04109576 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 2,000 4,128E-03 0,04337602 ! immunoglobulin mediated immune response GO:0016064 83 49 2,000 4,128E-03 0,04318743 GO:0019724|B cell mediated immunity, ! positive regulation of cell size GO:0045793 27 15 1,000 4,268E-03 0,04445517 ! vesicle coating GO:0006901 33 15 1,000 4,268E-03 0,04426355 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 4,268E-03 0,04407358 ! regulation of vasodilation GO:0042312 26 15 1,000 4,268E-03 0,04388523 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 4,268E-03 0,04369849 ! muscle maintenance GO:0046716 26 15 1,000 4,268E-03 0,04351332 ! cell killing GO:0001906 29 15 1,000 4,268E-03 0,04332972 ! lymphocyte homeostasis GO:0002260 30 15 1,000 4,268E-03 0,04314767 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 4,268E-03 0,04296713 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 1,000 4,268E-03 0,0427881 ! positive regulation of cytokine production GO:0001819 86 50 2,000 4,371E-03 0,04363711 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 4,622E-03 0,04595184 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 2,000 4,622E-03 0,04576274 ! vesicle organization GO:0016050 107 51 2,000 4,622E-03 0,04557519 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 4,622E-03 0,04538917 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 2,000 4,622E-03 0,04520466 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,857E-03 0,04731008 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,857E-03 0,04711931 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 4,857E-03 0,04693008 ! activation of MAPKK activity GO:0000186 35 16 1,000 4,857E-03 0,04674236 ! complement activation, alternative pathway GO:0006957 18 16 1,000 4,857E-03 0,04655613 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,857E-03 0,04637138 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 1,000 4,857E-03 0,0461881 ! regulation of angiogenesis GO:0045765 114 52 2,000 4,881E-03 0,04623905 ! membrane fusion GO:0006944 110 52 2,000 4,881E-03 0,04605772 ! amino acid activation GO:0043038 92 52 2,000 4,881E-03 0,04587781 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! response to UV GO:0009411 104 53 2,000 5,15E-03 0,04820955 ! positive regulation of cell killing GO:0031343 32 17 1,000 5,481E-03 0,05111095 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 5,481E-03 0,05091361 ! signal complex assembly GO:0007172 41 17 1,000 5,481E-03 0,05071779 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 1,000 5,481E-03 0,05052347 ! limbic system development GO:0021761 36 17 1,000 5,481E-03 0,05033063 ! heart looping GO:0001947 30 17 1,000 5,481E-03 0,05013926 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 1,000 5,481E-03 0,04994934 ! membrane budding GO:0006900 37 17 1,000 5,481E-03 0,04976085 ! neural crest cell migration GO:0001755 37 17 1,000 5,481E-03 0,04957378 ! folic acid and derivative metabolic process GO:0006760 33 17 1,000 5,481E-03 0,04938811 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 5,481E-03 0,04920383 ! glucose catabolic process GO:0006007 82 55 2,000 5,712E-03 0,05108981 ! regulation of protein catabolic process GO:0042176 116 55 2,000 5,712E-03 0,05090059 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 5,712E-03 0,05071276 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,139E-03 0,05430548 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 6,139E-03 0,05410656 ! patterning of blood vessels GO:0001569 39 18 1,000 6,139E-03 0,05390909 ! cell-substrate junction assembly GO:0007044 54 18 1,000 6,139E-03 0,05371306 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 6,139E-03 0,05351845 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 6,139E-03 0,05332524 ! regulation of intracellular transport GO:0032386 101 57 2,000 6,31E-03 0,05461037 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 6,832E-03 0,05891698 ! lipid phosphorylation GO:0046834 35 19 1,000 6,832E-03 0,05870656 ! pigmentation during development GO:0048066 41 19 1,000 6,832E-03 0,05849764 ! actin filament bundle formation GO:0051017 42 19 1,000 6,832E-03 0,0582902 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 6,832E-03 0,05808423 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 6,832E-03 0,05787971 ! establishment of organelle localization GO:0051656 109 59 2,000 6,944E-03 0,05862019 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 7,274E-03 0,06119626 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 7,558E-03 0,06336488 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 7,558E-03 0,06314487 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 35 20 1,000 7,558E-03 0,06292637 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 7,558E-03 0,06270938 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 7,558E-03 0,06249389 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 7,558E-03 0,06227987 ! peptidyl-serine modification GO:0018209 43 20 1,000 7,558E-03 0,06206731 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 1,000 7,558E-03 0,0618562 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 7,558E-03 0,06164651 ! actin filament-based movement GO:0030048 43 20 1,000 7,558E-03 0,06143825 ! regulation of cell killing GO:0031341 42 21 1,000 8,318E-03 0,06738592 ! inactivation of MAPK activity GO:0000188 39 21 1,000 8,318E-03 0,0671598 ! cytolysis GO:0019835 24 21 1,000 8,318E-03 0,06693518 ! regulation of vasoconstriction GO:0019229 39 21 1,000 8,318E-03 0,06671206 ! collagen fibril organization GO:0030199 59 21 1,000 8,318E-03 0,06649043 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 8,318E-03 0,06627026 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 8,318E-03 0,06605155 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 9,111E-03 0,07210662 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 9,111E-03 0,0718702 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 9,111E-03 0,07163533 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 9,111E-03 0,07140199 ! activation of JUN kinase activity GO:0007257 42 22 1,000 9,111E-03 0,07117017 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 9,111E-03 0,07093984 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 9,111E-03 0,07071101 ! activation of MAPK activity GO:0000187 115 67 2,000 9,849E-03 0,07619169 ! hexose catabolic process GO:0019320 104 67 2,000 9,849E-03 0,07594749 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 9,849E-03 0,07570484 ! positive regulation of T cell activation GO:0050870 109 67 2,000 9,849E-03 0,07546375 ! activation of immune response GO:0002253 105 67 2,000 9,849E-03 0,07522418 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 9,936E-03 0,07564872 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 9,936E-03 0,07541008 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 9,936E-03 0,07517294 ! vesicle targeting GO:0006903 43 23 1,000 9,936E-03 0,07493729 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 9,936E-03 0,07470311 ! synaptic vesicle transport GO:0048489 46 23 1,000 9,936E-03 0,07447039 ! platelet activation GO:0030168 37 23 1,000 9,936E-03 0,07423911 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 1,000 9,936E-03 0,07400927 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 0,01025406 0,07614589 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 0,0107923 0,07989622 GO:0002708|positive regulation of lymphocyte mediated immunity, ! membrane depolarization GO:0051899 39 24 1,000 0,0107923 0,07965114 ! pallium development GO:0021543 49 24 1,000 0,0107923 0,07940756 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,0107923 0,07916546 ! humoral immune response GO:0006959 109 71 2,000 0,0115282 0,08430654 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 0,0115282 0,08405107 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 0,01168045 0,08490381 ! receptor metabolic process GO:0043112 46 25 1,000 0,01168045 0,08464808 ! interaction with host GO:0051701 62 25 1,000 0,01168045 0,08439388 ! regulation of blood coagulation GO:0030193 40 25 1,000 0,01168045 0,0841412 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 0,01168045 0,08389004 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 0,01168045 0,08364036 ! vasculogenesis GO:0001570 46 25 1,000 0,01168045 0,08339217 ! neural crest cell development GO:0014032 54 25 1,000 0,01168045 0,08314545 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 0,01168045 0,08290018 GO:0050768|negative regulation of neurogenesis, ! regulation of caspase activity GO:0043281 122 72 2,000 0,01197225 0,08472124 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 0,01197225 0,0844728 ! carbohydrate transport GO:0008643 110 72 2,000 0,01197225 0,0842258 ! regulation of interferon-gamma production GO:0032649 39 26 1,000 0,01259958 0,08838073 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 0,01259958 0,08812381 ! molting cycle process GO:0022404 50 26 1,000 0,01259958 0,08786838 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01259958 0,08761442 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 0,01259958 0,08736193 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01259958 0,08711089 ! regulation of response to biotic stimulus GO:0002831 44 26 1,000 0,01259958 0,08686129 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01259958 0,08661312 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 0,01259958 0,08636636 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 0,01259958 0,086121 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01288953 0,08785331 ! organelle localization GO:0051640 136 74 2,000 0,01288953 0,08760514 ! cell-matrix adhesion GO:0007160 163 75 2,000 0,01336284 0,09056617 ! neuron fate commitment GO:0048663 48 27 1,000 0,01354925 0,09157162 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 0,01354925 0,09131511 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01354925 0,09106004 ! fat cell differentiation GO:0045444 50 27 1,000 0,01354925 0,0908064 ! positive regulation of innate immune response GO:0045089 43 27 1,000 0,01354925 0,09055416 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01354925 0,09030331 ! response to toxin GO:0009636 47 27 1,000 0,01354925 0,09005386 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01354925 0,08980577 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01354925 0,08955905 ! monosaccharide catabolic process GO:0046365 115 76 2,000 0,01384595 0,0912695 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01433891 0,09426068 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01452902 0,09525021 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01452902 0,09499138 ! protein oligomerization GO:0051259 139 78 2,000 0,01484172 0,09677283 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 0,01535441 0,09984518 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,01535441 0,09957606 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 0,01535441 0,09930838 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01553846 0,10022933 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01553846 0,09996134 ! regulation of coagulation GO:0050818 46 29 1,000 0,01553846 0,09969478 ! protein import into nucleus GO:0006606 158 80 2,000 0,01587701 0,10159596 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01640952 0,10472498 ! nuclear import GO:0051170 161 81 2,000 0,01640952 0,10444793 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 0,01640952 0,10417234 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 2,000 0,01640952 0,1038982 ! cell junction assembly GO:0034329 78 30 1,000 0,01657714 0,10468401 ! regulation of innate immune response GO:0045088 51 30 1,000 0,01657714 0,10440997 ! acute-phase response GO:0006953 49 30 1,000 0,01657714 0,10413736 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,01657714 0,10386617 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01657714 0,10359639 ! response to heat GO:0009408 50 30 1,000 0,01657714 0,103328 ! response to oxygen levels GO:0070482 176 83 2,000 0,01750438 0,1088257 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01764464 0,10941497 ! mRNA export from nucleus GO:0006406 48 31 1,000 0,01764464 0,1091337 ! collagen metabolic process GO:0032963 45 31 1,000 0,01764464 0,10885387 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01764464 0,10857547 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01764464 0,1082985 ! peptide transport GO:0015833 55 31 1,000 0,01764464 0,10802293 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01764464 0,10774876 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01764464 0,10747598 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01764464 0,10720457 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,0186391 0,11296137 GO:0002696|positive regulation of leukocyte activation, ! cholesterol transport GO:0030301 56 32 1,000 0,01874054 0,11329079 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01874054 0,11300685 ! alcohol catabolic process GO:0046164 130 86 2,000 0,01922143 0,11561688 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01981375 0,1188825 ! regulation of protein transport GO:0051223 154 87 2,000 0,01981375 0,11858678 GO:0070201|regulation of establishment of protein localization, ! post-embryonic development GO:0009791 69 33 1,000 0,01986442 0,118595 ! sterol transport GO:0015918 57 33 1,000 0,01986442 0,11830144 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01986442 0,11800934 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01986442 0,11771868 ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,02041608 0,12069061 ! regulation of DNA binding GO:0051101 155 88 2,000 0,02041608 0,1203948 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,02101586 0,12362877 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,02101586 0,12332723 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,0210284 0,12310059 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,02219447 0,12961141 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,02219447 0,12929758 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,02219447 0,12898527 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 1,000 0,02219447 0,12867446 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,02219447 0,12836515 ! vesicle localization GO:0051648 64 35 1,000 0,02219447 0,12805732 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02339984 0,13468905 ! cell junction organization GO:0034330 86 36 1,000 0,02339984 0,1343676 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02339984 0,13404767 ! embryonic organ development GO:0048568 57 36 1,000 0,02339984 0,13372927 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,02357782 0,13442711 ! regulation of T cell activation GO:0050863 158 94 2,000 0,0242402 0,13787689 ! RNA export from nucleus GO:0006405 56 37 1,000 0,02463157 0,13977256 ! meiosis I GO:0007127 65 37 1,000 0,02463157 0,13944369 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02463157 0,13911636 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,02463157 0,13879056 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,02463157 0,13846628 ! glycogen metabolic process GO:0005977 61 37 1,000 0,02463157 0,13814351 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 0,02491258 0,13939459 ! forebrain development GO:0030900 188 95 2,000 0,02491258 0,13907117 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,02491258 0,13874924 ! mRNA transport GO:0051028 169 96 2,000 0,02559496 0,14222051 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02588927 0,14352439 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 1,000 0,02588927 0,14319445 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,02588927 0,14286602 ! glucan metabolic process GO:0044042 62 38 1,000 0,02588927 0,1425391 GO:0006073|cellular glucan metabolic process, ! protein ubiquitination GO:0016567 217 97 2,000 0,02628734 0,14440029 ! regulation of protein localization GO:0032880 176 97 2,000 0,02628734 0,14407136 ! interphase GO:0051325 213 98 2,000 0,02698969 0,14758454 ! mammary gland development GO:0030879 86 39 1,000 0,02717254 0,14824748 ! organic ether metabolic process GO:0018904 55 39 1,000 0,02717254 0,14791208 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,02717254 0,14757819 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02717254 0,14724581 ! RNA modification GO:0009451 57 39 1,000 0,02717254 0,14691492 ! negative regulation of binding GO:0051100 72 40 1,000 0,028481 0,15364415 ! mesenchymal cell development GO:0014031 87 40 1,000 0,028481 0,15330043 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,028481 0,15295824 ! maintenance of protein location GO:0045185 91 40 1,000 0,028481 0,15261758 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02981427 0,15940695 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,03117196 0,16629652 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,03117196 0,16592861 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03244454 0,17232131 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03244454 0,17194175 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03244454 0,17156386 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03244454 0,17118762 ! neuron fate determination GO:0048664 7 5 0,000 0,03244454 0,17081303 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03244454 0,17044008 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03244454 0,17006875 ! polyol transport GO:0015791 12 5 0,000 0,03244454 0,16969903 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03244454 0,16933092 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03244454 0,1689644 ! response to superoxide GO:0000303 10 5 0,000 0,03244454 0,16859947 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03244454 0,16823611 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03244454 0,16787431 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03244454 0,16751407 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03244454 0,16715536 ! female meiosis GO:0007143 7 5 0,000 0,03244454 0,16679819 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03244454 0,16644255 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03244454 0,16608841 ! cobalt ion transport GO:0006824 11 5 0,000 0,03244454 0,16573578 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03244454 0,16538465 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03244454 0,165035 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03244454 0,16468682 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03244454 0,16434012 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03244454 0,16399486 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03244454 0,16365106 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03244454 0,16330869 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03244454 0,16296776 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03244454 0,16262824 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03244454 0,16229013 ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03244454 0,16195343 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,03244454 0,16161813 ! negative chemotaxis GO:0050919 14 5 0,000 0,03244454 0,1612842 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03244454 0,16095166 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03244454 0,16062048 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03244454 0,16029067 ! behavioral response to pain GO:0048266 9 5 0,000 0,03244454 0,1599622 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03244454 0,15963508 ! Notch receptor processing GO:0007220 8 5 0,000 0,03244454 0,1593093 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03244454 0,15898484 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03244454 0,1586617 ! micturition GO:0060073 9 5 0,000 0,03244454 0,15833987 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03244454 0,15801934 ! copulation GO:0007620 9 5 0,000 0,03244454 0,15770011 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03244454 0,15738217 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03244454 0,1570655 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03244454 0,15675011 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03244454 0,15643598 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03244454 0,15612311 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03244454 0,15581149 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03244454 0,1555011 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03244454 0,15519196 ! grooming behavior GO:0007625 6 5 0,000 0,03244454 0,15488404 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03244454 0,15457734 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03244454 0,15427185 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03244454 0,15396756 ! response to protozoan GO:0001562 10 5 0,000 0,03244454 0,15366448 ! lymph vessel development GO:0001945 10 5 0,000 0,03244454 0,15336258 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03244454 0,15306187 ! endochondral ossification GO:0001958 16 5 0,000 0,03244454 0,15276234 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03244454 0,15246397 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03244454 0,15216677 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03244454 0,15187073 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03244454 0,15157583 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03244454 0,15128208 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03244454 0,15098947 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03244454 0,15069798 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03244454 0,15040762 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03244454 0,15011837 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03244454 0,14983024 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03244454 0,14954321 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03244454 0,14925727 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03244454 0,14897243 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03244454 0,14868868 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03244454 0,148406 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03244454 0,14812439 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03244454 0,14784385 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,03244454 0,14756438 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03244454 0,14728595 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03244454 0,14700858 ! histidine catabolic process GO:0006548 6 5 0,000 0,03244454 0,14673225 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03244454 0,14645695 ! microvillus organization GO:0032528 7 5 0,000 0,03244454 0,14618269 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03244454 0,14590945 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03244454 0,14563723 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03244454 0,14536602 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03244454 0,14509583 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03244454 0,14482663 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03244454 0,14455843 ! polyol catabolic process GO:0046174 7 5 0,000 0,03244454 0,14429123 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03244454 0,14402501 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03244454 0,14375977 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03244454 0,1434955 ! muscle cell migration GO:0014812 8 5 0,000 0,03244454 0,14323221 ! mitochondrial fission GO:0000266 8 5 0,000 0,03244454 0,14296988 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03244454 0,14270851 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03244454 0,14244809 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03244454 0,14218862 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03244454 0,1419301 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03244454 0,14167251 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03244454 0,14141586 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03244454 0,14116014 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03244454 0,14090533 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03244454 0,14065145 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03244454 0,14039848 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03244454 0,14014642 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03244454 0,13989526 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,03244454 0,139645 ! forebrain neuron development GO:0021884 13 5 0,000 0,03244454 0,13939563 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03244454 0,13914716 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03244454 0,13889956 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03244454 0,13865285 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03244454 0,13840701 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03244454 0,13816204 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03244454 0,13791794 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03244454 0,1376747 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03244454 0,13743231 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03244454 0,13719078 ! basic amino acid transport GO:0015802 11 5 0,000 0,03244454 0,1369501 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03244454 0,13671025 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03244454 0,13647125 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03244454 0,13623308 ! depyrimidination GO:0045008 10 5 0,000 0,03244454 0,13599574 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03244454 0,13575923 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03244454 0,13552353 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03244454 0,13528866 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03244454 0,13505459 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03244454 0,13482134 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03244454 0,13458889 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03244454 0,13435724 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03244454 0,13412638 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03244454 0,13389632 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03244454 0,13366705 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03244454 0,13343856 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03244454 0,13321084 ! response to arsenic GO:0046685 10 5 0,000 0,03244454 0,13298391 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03244454 0,13275775 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03244454 0,13253235 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03244454 0,13230772 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03244454 0,13208385 ! response to cadmium ion GO:0046686 7 5 0,000 0,03244454 0,13186073 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03244454 0,13163837 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03244454 0,13141676 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03244454 0,13119589 ! decidualization GO:0046697 11 5 0,000 0,03244454 0,13097576 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03244454 0,13075637 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03244454 0,13053772 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03244454 0,13031979 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03244454 0,13010259 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03244454 0,12988611 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03244454 0,12967036 ! neural tube patterning GO:0021532 7 5 0,000 0,03244454 0,12945531 ! embryonic cleavage GO:0040016 6 5 0,000 0,03244454 0,12924098 ! peroxisome fission GO:0016559 5 5 0,000 0,03244454 0,12902736 ! histone demethylation GO:0016577 10 5 0,000 0,03244454 0,12881445 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03244454 0,12860223 ! mitotic recombination GO:0006312 9 5 0,000 0,03244454 0,12839071 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03244454 0,12817989 ! metaphase plate congression GO:0051310 7 5 0,000 0,03244454 0,12796976 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03244454 0,12776032 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,03244454 0,12755156 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03244454 0,12734348 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03244454 0,12713608 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03244454 0,12692936 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03244454 0,1267233 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03244454 0,12651792 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03244454 0,1263132 ! plasminogen activation GO:0031639 5 5 0,000 0,03244454 0,12610914 ! B cell homeostasis GO:0001782 13 5 0,000 0,03244454 0,12590573 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03244454 0,12570299 ! metaphase GO:0051323 8 5 0,000 0,03244454 0,12550089 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03244454 0,12529945 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03244454 0,12509865 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03244454 0,12489849 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03244454 0,12469897 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03244454 0,12450009 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03244454 0,12430184 ! response to redox state GO:0051775 5 5 0,000 0,03244454 0,12410422 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03244454 0,12390723 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03244454 0,12371086 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03244454 0,12351512 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03244454 0,12331999 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03244454 0,12312548 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03244454 0,12293158 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03244454 0,12273829 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03244454 0,12254561 ! striatum development GO:0021756 9 5 0,000 0,03244454 0,12235353 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03244454 0,12216206 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03244454 0,12197118 ! glial cell migration GO:0008347 11 5 0,000 0,03244454 0,1217809 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03244454 0,12159121 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,03244454 0,12140211 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03244454 0,12121359 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03244454 0,12102567 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03244454 0,12083832 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03244454 0,12065155 ! neuroprotection GO:0043526 6 5 0,000 0,03244454 0,12046536 ! neural plate development GO:0001840 8 5 0,000 0,03244454 0,12027975 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03244454 0,1200947 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03244454 0,11991022 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03244454 0,11972631 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03244454 0,11954296 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03244454 0,11936018 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03244454 0,11917795 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03244454 0,11899627 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03244454 0,11881515 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03244454 0,11863458 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03244454 0,11845456 ! spindle assembly GO:0051225 6 5 0,000 0,03244454 0,11827508 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03244454 0,11809615 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03244454 0,11791776 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03244454 0,1177399 ! drug metabolic process GO:0017144 6 5 0,000 0,03244454 0,11756258 ! stem cell division GO:0017145 11 5 0,000 0,03244454 0,1173858 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,03244454 0,11720954 ! organ regeneration GO:0031100 7 5 0,000 0,03244454 0,11703382 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03244454 0,11685861 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03244454 0,11668394 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03244454 0,11650978 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,0325537 0,11672757 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,0325537 0,11655387 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,03395912 0,12140511 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,03395912 0,12122499 ! developmental growth GO:0048589 82 44 1,000 0,03395912 0,12104539 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03395912 0,12086633 ! leukocyte migration GO:0050900 68 45 1,000 0,03538785 0,12576539 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,03538785 0,12557989 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,03538785 0,12539495 ! pigmentation GO:0043473 100 46 1,000 0,03683953 0,13034692 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03683953 0,13015552 ! positive regulation of defense response GO:0031349 76 47 1,000 0,0383138 0,13516568 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,0383138 0,13496778 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,0383138 0,13477046 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03880665 0,13630482 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03880665 0,13610612 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03880665 0,13590801 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03880665 0,13571047 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03880665 0,1355135 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03880665 0,1353171 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03880665 0,13512128 ! sleep GO:0030431 13 6 0,000 0,03880665 0,13492601 ! response to oxygen radical GO:0000305 11 6 0,000 0,03880665 0,13473132 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03880665 0,13453718 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03880665 0,1343436 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03880665 0,13415058 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03880665 0,13395811 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03880665 0,13376619 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03880665 0,13357482 ! forebrain regionalization GO:0021871 8 6 0,000 0,03880665 0,133384 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03880665 0,13319373 ! male meiosis GO:0007140 7 6 0,000 0,03880665 0,13300399 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03880665 0,1328148 ! response to zinc ion GO:0010043 9 6 0,000 0,03880665 0,13262614 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03880665 0,13243802 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03880665 0,13225043 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03880665 0,13206337 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03880665 0,13187684 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03880665 0,13169083 ! malate metabolic process GO:0006108 11 6 0,000 0,03880665 0,13150535 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03880665 0,1313204 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03880665 0,13113596 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03880665 0,13095204 ! opsonization GO:0008228 8 6 0,000 0,03880665 0,13076863 ! mating behavior GO:0007617 7 6 0,000 0,03880665 0,13058574 ! neuron remodeling GO:0016322 15 6 0,000 0,03880665 0,13040335 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03880665 0,13022148 ! equilibrioception GO:0050957 14 6 0,000 0,03880665 0,13004011 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03880665 0,12985925 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03880665 0,12967889 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03880665 0,12949903 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03880665 0,12931967 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03880665 0,1291408 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03880665 0,12896243 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03880665 0,12878455 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03880665 0,12860716 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03880665 0,12843026 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03880665 0,12825385 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03880665 0,12807792 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03880665 0,12790247 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03880665 0,1277275 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03880665 0,12755301 ! thymic T cell selection GO:0045061 12 6 0,000 0,03880665 0,12737899 ! protein lipoylation GO:0009249 10 6 0,000 0,03880665 0,12720545 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03880665 0,12703238 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03880665 0,12685978 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03880665 0,12668765 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03880665 0,12651599 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03880665 0,12634479 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03880665 0,12617406 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03880665 0,12600378 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03880665 0,12583396 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03880665 0,1256646 ! hyperosmotic response GO:0006972 9 6 0,000 0,03880665 0,1254957 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03880665 0,12532725 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03880665 0,12515925 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03880665 0,1249917 ! urea metabolic process GO:0019627 7 6 0,000 0,03880665 0,1248246 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03880665 0,12465795 ! neutrophil activation GO:0042119 8 6 0,000 0,03880665 0,12449174 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03880665 0,12432597 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03880665 0,12416064 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03880665 0,12399575 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03880665 0,1238313 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03880665 0,12366729 ! neuron apoptosis GO:0051402 9 6 0,000 0,03880665 0,12350371 ! nucleoside salvage GO:0043174 9 6 0,000 0,03880665 0,12334056 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03880665 0,12317784 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03880665 0,12301555 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03880665 0,12285369 ! carnitine transport GO:0015879 10 6 0,000 0,03880665 0,12269225 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03880665 0,12253124 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03880665 0,12237064 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03880665 0,12221047 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03880665 0,12205072 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03880665 0,12189139 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03880665 0,12173247 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03880665 0,12157396 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03880665 0,12141587 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03880665 0,12125818 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03880665 0,12110091 ! monocyte differentiation GO:0030224 12 6 0,000 0,03880665 0,12094404 ! neural nucleus development GO:0048857 14 6 0,000 0,03880665 0,12078758 ! response to UV-C GO:0010225 11 6 0,000 0,03880665 0,12063153 ! astrocyte development GO:0014002 15 6 0,000 0,03880665 0,12047587 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03880665 0,12032062 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03880665 0,12016577 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03880665 0,12001131 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03880665 0,11985725 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03880665 0,11970359 ! response to copper ion GO:0046688 10 6 0,000 0,03880665 0,11955032 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03880665 0,11939744 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03880665 0,11924496 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03880665 0,11909286 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03880665 0,11894115 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03880665 0,11878982 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03880665 0,11863888 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03880665 0,11848833 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03880665 0,11833815 ! Schwann cell development GO:0014044 15 6 0,000 0,03880665 0,11818836 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03880665 0,11803894 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03880665 0,1178899 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03880665 0,11774124 ! subpallium development GO:0021544 10 6 0,000 0,03880665 0,11759295 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03880665 0,11744503 ! histone ubiquitination GO:0016574 8 6 0,000 0,03880665 0,11729749 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03880665 0,11715032 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03880665 0,11700351 ! G2 phase GO:0051319 16 6 0,000 0,03880665 0,11685707 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03880665 0,116711 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03880665 0,1165653 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03880665 0,11641995 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03880665 0,11627497 ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03880665 0,11613035 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03880665 0,11598609 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03880665 0,11584219 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03880665 0,11569864 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03880665 0,11555545 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03880665 0,11541261 ! protein deubiquitination GO:0016579 14 6 0,000 0,03880665 0,11527013 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03880665 0,11512799 ! protein destabilization GO:0031648 9 6 0,000 0,03880665 0,11498621 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03880665 0,11484477 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03880665 0,11470369 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03880665 0,11456295 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03880665 0,11442255 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03880665 0,1142825 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03880665 0,11414279 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03880665 0,11400342 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03880665 0,11386439 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03880665 0,1137257 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03880665 0,11358735 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03880665 0,11344933 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03880665 0,11331165 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03880665 0,1131743 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03880665 0,11303729 ! catecholamine transport GO:0051937 9 6 0,000 0,03880665 0,11290061 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03880665 0,11276425 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03880665 0,11262823 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03880665 0,11249253 ! maternal placenta development GO:0001893 12 6 0,000 0,03880665 0,11235716 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03880665 0,11222212 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03880665 0,1120874 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03880665 0,111953 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03880665 0,11181892 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03880665 0,11168517 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03880665 0,11155173 ! mitochondrial transport GO:0006839 82 48 1,000 0,03981029 0,1143002 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03981029 0,11416396 ! activation of caspase activity GO:0006919 84 48 1,000 0,03981029 0,11402805 ! response to temperature stimulus GO:0009266 76 49 1,000 0,04132867 0,11823635 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,04286857 0,12249618 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,04442966 0,12680636 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,04442966 0,12665612 ! excretion GO:0007588 83 51 1,000 0,04442966 0,12650623 ! tRNA transcription GO:0009304 14 7 0,000 0,04512714 0,12834031 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04512714 0,12818879 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04512714 0,12803762 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04512714 0,12788681 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04512714 0,12773635 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04512714 0,12758625 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04512714 0,1274365 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04512714 0,12728711 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04512714 0,12713806 ! prostate gland development GO:0030850 13 7 0,000 0,04512714 0,12698936 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04512714 0,12684101 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04512714 0,126693 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04512714 0,12654534 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04512714 0,12639802 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04512714 0,12625105 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04512714 0,12610441 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04512714 0,12595812 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04512714 0,12581217 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04512714 0,12566655 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04512714 0,12552127 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04512714 0,12537633 ! glycolipid transport GO:0046836 10 7 0,000 0,04512714 0,12523172 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04512714 0,12508744 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04512714 0,1249435 ! neuron adhesion GO:0007158 12 7 0,000 0,04512714 0,12479989 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04512714 0,1246566 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04512714 0,12451365 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04512714 0,12437102 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04512714 0,12422872 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04512714 0,12408674 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04512714 0,12394509 ! mRNA stabilization GO:0048255 18 7 0,000 0,04512714 0,12380376 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04512714 0,12366276 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04512714 0,12352207 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04512714 0,12338171 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04512714 0,12324166 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04512714 0,12310193 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04512714 0,12296252 ! lipoprotein transport GO:0042953 14 7 0,000 0,04512714 0,12282342 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04512714 0,12268463 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04512714 0,12254616 ! rhythmic behavior GO:0007622 15 7 0,000 0,04512714 0,12240801 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04512714 0,12227016 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04512714 0,12213262 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04512714 0,12199539 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04512714 0,12185847 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04512714 0,12172186 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04512714 0,12158556 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04512714 0,12144955 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04512714 0,12131386 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04512714 0,12117846 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04512714 0,12104337 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04512714 0,12090858 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04512714 0,12077408 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04512714 0,12063989 ! spinal cord patterning GO:0021511 13 7 0,000 0,04512714 0,12050599 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04512714 0,1203724 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04512714 0,12023909 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04512714 0,12010609 ! adrenal gland development GO:0030325 17 7 0,000 0,04512714 0,11997337 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04512714 0,11984095 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04512714 0,11970882 ! ovulation GO:0030728 9 7 0,000 0,04512714 0,11957698 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04512714 0,11944544 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04512714 0,11931418 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04512714 0,11918321 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04512714 0,11905252 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04512714 0,11892213 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04512714 0,11879201 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04512714 0,11866219 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04512714 0,11853264 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04512714 0,11840338 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04512714 0,1182744 ! galactose metabolic process GO:0006012 13 7 0,000 0,04512714 0,1181457 ! response to dietary excess GO:0002021 8 7 0,000 0,04512714 0,11801728 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04512714 0,11788914 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04512714 0,11776128 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04512714 0,1176337 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04512714 0,11750639 ! organ growth GO:0035265 15 7 0,000 0,04512714 0,11737935 ! purine salvage GO:0043101 10 7 0,000 0,04512714 0,11725259 ! nucleoside transport GO:0015858 8 7 0,000 0,04512714 0,11712611 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04512714 0,11699989 ! parturition GO:0007567 14 7 0,000 0,04512714 0,11687395 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04512714 0,11674828 ! rRNA modification GO:0000154 14 7 0,000 0,04512714 0,11662288 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04512714 0,11649775 ! spindle checkpoint GO:0031577 15 7 0,000 0,04512714 0,11637288 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04512714 0,11624829 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04512714 0,11612396 ! macrophage differentiation GO:0030225 11 7 0,000 0,04512714 0,11599989 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04512714 0,1158761 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04512714 0,11575256 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04512714 0,11562929 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04512714 0,11550628 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04512714 0,11538353 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04512714 0,11526104 ! fibrinolysis GO:0042730 10 7 0,000 0,04512714 0,11513881 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04512714 0,11501684 ! eating behavior GO:0042755 7 7 0,000 0,04512714 0,11489513 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04512714 0,11477368 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04512714 0,11465248 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04512714 0,11453154 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04512714 0,11441085 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04512714 0,11429042 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04512714 0,11417024 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04512714 0,11405032 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04512714 0,11393064 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04512714 0,11381122 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04512714 0,11369204 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04512714 0,11357312 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04512714 0,11345444 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04512714 0,11333601 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04512714 0,11321783 ! regulation of meiosis GO:0040020 12 7 0,000 0,04512714 0,1130999 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04512714 0,11298221 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04512714 0,11286476 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04512714 0,11274756 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04512714 0,1126306 ! transcription termination GO:0006353 13 7 0,000 0,04512714 0,11251389 ! response to tumor cell GO:0002347 13 7 0,000 0,04512714 0,11239741 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04512714 0,11228118 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04512714 0,11216519 ! anaphase GO:0051322 17 7 0,000 0,04512714 0,11204943 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04512714 0,11193392 ! axonal fasciculation GO:0007413 18 7 0,000 0,04512714 0,11181864 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04512714 0,1117036 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04512714 0,1115888 ! diuresis GO:0030146 12 7 0,000 0,04512714 0,11147423 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04512714 0,1113599 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04512714 0,1112458 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04512714 0,11113194 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04512714 0,1110183 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04512714 0,1109049 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04512714 0,11079174 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04512714 0,1106788 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04512714 0,11056609 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04512714 0,11045361 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04512714 0,11034136 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04512714 0,11022934 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04512714 0,11011755 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04512714 0,11000598 ! lymph node development GO:0048535 10 7 0,000 0,04512714 0,10989464 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04512714 0,10978352 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04512714 0,10967263 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04512714 0,10956196 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04512714 0,10945151 ! adult feeding behavior GO:0008343 9 7 0,000 0,04512714 0,10934129 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04512714 0,10923129 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04512714 0,10912151 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04512714 0,10901195 ! muscle adaptation GO:0043500 14 7 0,000 0,04512714 0,10890261 ! retina homeostasis GO:0001895 12 7 0,000 0,04512714 0,10879349 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04512714 0,10868459 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04512714 0,1085759 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04512714 0,10846743 ! protein prenylation GO:0018342 18 7 0,000 0,04512714 0,10835918 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04512714 0,10825115 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,04601159 0,11026283 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,04601159 0,11015312 ! cartilage development GO:0051216 90 52 1,000 0,04601159 0,11004362 ! regulation of translational initiation GO:0006446 82 53 1,000 0,04761402 0,11376299 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,04923662 0,11752313 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,05087906 0,12132311 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,05087906 0,12120299 ! heart morphogenesis GO:0003007 97 55 1,000 0,05087906 0,1210831 ! nuclear export GO:0051168 97 55 1,000 0,05087906 0,12096345 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05140628 0,12209625 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05140628 0,12197584 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05140628 0,12185567 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05140628 0,12173573 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05140628 0,12161603 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,05140628 0,12149657 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05140628 0,12137734 ! meiotic prophase I GO:0007128 13 8 0,000 0,05140628 0,12125834 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05140628 0,12113957 ! UTP metabolic process GO:0046051 8 8 0,000 0,05140628 0,12102104 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,05140628 0,12090274 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05140628 0,12078467 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05140628 0,12066683 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05140628 0,12054923 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05140628 0,12043185 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,05140628 0,12031469 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05140628 0,12019777 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,05140628 0,12008107 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05140628 0,1199646 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05140628 0,11984836 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05140628 0,11973234 ! reflex GO:0060004 16 8 0,000 0,05140628 0,11961654 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05140628 0,11950097 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05140628 0,11938562 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05140628 0,1192705 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,05140628 0,11915559 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05140628 0,11904091 ! pigment granule organization GO:0048753 16 8 0,000 0,05140628 0,11892645 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,05140628 0,11881221 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05140628 0,11869818 ! astrocyte differentiation GO:0048708 18 8 0,000 0,05140628 0,11858438 ! histidine metabolic process GO:0006547 16 8 0,000 0,05140628 0,11847079 GO:0009075|histidine family amino acid metabolic process, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05140628 0,11835742 ! glycine catabolic process GO:0006546 13 8 0,000 0,05140628 0,11824427 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05140628 0,11813133 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05140628 0,11801861 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,05140628 0,11790611 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05140628 0,11779381 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,05140628 0,11768174 ! melanin metabolic process GO:0006582 15 8 0,000 0,05140628 0,11756987 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05140628 0,11745822 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05140628 0,11734678 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,05140628 0,11723555 ! macrophage activation GO:0042116 12 8 0,000 0,05140628 0,11712453 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05140628 0,11701372 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,05140628 0,11690312 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05140628 0,11679273 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05140628 0,11668255 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05140628 0,11657258 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05140628 0,11646281 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05140628 0,11635325 ! osteoblast development GO:0002076 16 8 0,000 0,05140628 0,1162439 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05140628 0,11613475 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05140628 0,1160258 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05140628 0,11591706 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,05140628 0,11580853 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05140628 0,11570019 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05140628 0,11559206 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05140628 0,11548413 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05140628 0,1153764 ! intermediate filament organization GO:0045109 12 8 0,000 0,05140628 0,11526888 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05140628 0,11516155 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,05140628 0,11505442 ! cellular extravasation GO:0045123 12 8 0,000 0,05140628 0,1149475 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05140628 0,11484077 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05140628 0,11473424 ! response to antibiotic GO:0046677 11 8 0,000 0,05140628 0,1146279 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05140628 0,11452176 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05140628 0,11441582 ! DNA topological change GO:0006265 12 8 0,000 0,05140628 0,11431008 ! response to tropane GO:0014073 15 8 0,000 0,05140628 0,11420453 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05140628 0,11409917 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,05140628 0,11399401 ! melanosome transport GO:0032402 13 8 0,000 0,05140628 0,11388905 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05140628 0,11378427 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05140628 0,11367969 ! mast cell activation GO:0045576 14 8 0,000 0,05140628 0,1135753 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05140628 0,11347111 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05140628 0,1133671 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05140628 0,11326328 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05140628 0,11315966 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05140628 0,11305622 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05140628 0,11295297 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,05140628 0,11284991 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05140628 0,11274704 GO:0002263|cell activation during immune response, ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05140628 0,11264436 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05140628 0,11254186 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05140628 0,11243955 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05140628 0,11233743 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05140628 0,11223549 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05140628 0,11213373 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05140628 0,11203216 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05140628 0,11193077 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05140628 0,11182957 ! hormone catabolic process GO:0042447 17 8 0,000 0,05140628 0,11172855 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05140628 0,11162771 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05140628 0,11152706 ! ATP catabolic process GO:0006200 11 8 0,000 0,05140628 0,11142658 ! blastocyst growth GO:0001832 19 8 0,000 0,05140628 0,11132629 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05140628 0,11122617 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05140628 0,11112624 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05140628 0,11102649 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05140628 0,11092691 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05140628 0,11082751 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05140628 0,1107283 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05140628 0,11062925 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05140628 0,11053039 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05140628 0,1104317 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05140628 0,11033319 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05140628 0,11023485 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05140628 0,11013669 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05140628 0,11003871 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05140628 0,10994089 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05140628 0,10984326 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05140628 0,10974579 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,05422213 0,11565466 ! lipid modification GO:0030258 97 57 1,000 0,05422213 0,11555222 ! maintenance of location GO:0051235 118 57 1,000 0,05422213 0,11544996 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,05764067 0,1226202 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05764433 0,12251967 ! axon extension GO:0048675 15 9 0,000 0,05764433 0,12241153 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05764433 0,12230358 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05764433 0,12219583 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05764433 0,12208826 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05764433 0,12198088 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05764433 0,12187369 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05764433 0,12176669 ! phosphate transport GO:0006817 19 9 0,000 0,05764433 0,12165988 ! reproductive behavior GO:0019098 19 9 0,000 0,05764433 0,12155325 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05764433 0,12144681 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05764433 0,12134056 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05764433 0,1212345 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05764433 0,12112861 ! GTP metabolic process GO:0046039 9 9 0,000 0,05764433 0,12102292 ! RNA methylation GO:0001510 15 9 0,000 0,05764433 0,1209174 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05764433 0,12081208 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05764433 0,12070693 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05764433 0,12060197 ! regulation of histone modification GO:0031056 12 9 0,000 0,05764433 0,12049719 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05764433 0,12039259 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05764433 0,12028817 ! chemosensory behavior GO:0007635 20 9 0,000 0,05764433 0,12018394 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05764433 0,12007988 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05764433 0,11997601 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05764433 0,11987231 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05764433 0,11976879 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05764433 0,11966546 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05764433 0,1195623 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05764433 0,11945931 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05764433 0,11935651 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05764433 0,11925388 ! protein targeting to ER GO:0045047 22 9 0,000 0,05764433 0,11915143 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05764433 0,11904915 ! T cell selection GO:0045058 23 9 0,000 0,05764433 0,11894705 ! endosome organization GO:0007032 17 9 0,000 0,05764433 0,11884513 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05764433 0,11874338 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05764433 0,1186418 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05764433 0,1185404 ! mannose metabolic process GO:0006013 13 9 0,000 0,05764433 0,11843917 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05764433 0,11833811 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05764433 0,11823722 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05764433 0,11813651 ! receptor clustering GO:0043113 18 9 0,000 0,05764433 0,11803597 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05764433 0,1179356 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05764433 0,1178354 ! retinol metabolic process GO:0042572 18 9 0,000 0,05764433 0,11773537 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05764433 0,11763551 ! behavioral fear response GO:0001662 22 9 0,000 0,05764433 0,11753582 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05764433 0,11743629 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05764433 0,11733694 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,05764433 0,11723775 ! protein heterooligomerization GO:0051291 16 9 0,000 0,05764433 0,11713874 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05764433 0,11703988 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05764433 0,1169412 ! segment specification GO:0007379 13 9 0,000 0,05764433 0,11684268 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05764433 0,11674433 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05764433 0,11664614 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05764433 0,11654812 ! response to amine stimulus GO:0014075 13 9 0,000 0,05764433 0,11645026 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05764433 0,11635257 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05764433 0,11625504 ! erythrocyte development GO:0048821 15 9 0,000 0,05764433 0,11615767 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05764433 0,11606047 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05764433 0,11596343 ! renal water homeostasis GO:0003091 14 9 0,000 0,05764433 0,11586655 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05764433 0,11576984 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05764433 0,11567328 ! icosanoid secretion GO:0032309 15 9 0,000 0,05764433 0,11557689 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05764433 0,11548065 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05764433 0,11538458 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05764433 0,11528866 ! regulation of cell division GO:0051302 15 9 0,000 0,05764433 0,11519291 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05764433 0,11509731 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05764433 0,11500188 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05764433 0,1149066 ! sterol catabolic process GO:0016127 11 9 0,000 0,05764433 0,11481148 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05764433 0,11471651 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05764433 0,1146217 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05764433 0,11452705 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05764433 0,11443256 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05764433 0,11433822 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05764433 0,11424404 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05764433 0,11415001 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05764433 0,11405614 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05764433 0,11396242 ! purine base metabolic process GO:0006144 21 9 0,000 0,05764433 0,11386885 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05764433 0,11377544 ! pigment granule transport GO:0051904 17 9 0,000 0,05764433 0,11368218 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05764433 0,11358908 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05764433 0,11349612 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05764433 0,11340332 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05764433 0,11331067 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05764433 0,11321817 ! mitochondrion localization GO:0051646 15 9 0,000 0,05764433 0,11312583 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,05937744 0,11643204 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,05937744 0,11633722 ! camera-type eye development GO:0043010 116 60 1,000 0,05937744 0,11624256 ! kidney development GO:0001822 122 60 1,000 0,05937744 0,11614806 ! tRNA processing GO:0008033 89 61 1,000 0,06113212 0,11948326 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,06290442 0,12284744 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,06384157 0,12457649 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06384157 0,12447554 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06384157 0,12437475 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,06384157 0,12427412 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06384157 0,12417366 ! synapsis GO:0007129 13 10 0,000 0,06384157 0,12407336 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06384157 0,12397322 ! N-glycan processing GO:0006491 20 10 0,000 0,06384157 0,12387324 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06384157 0,12377342 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06384157 0,12367376 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06384157 0,12357427 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06384157 0,12347493 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06384157 0,12337576 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,06384157 0,12327674 ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06384157 0,12317788 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06384157 0,12307918 ! androgen metabolic process GO:0008209 17 10 0,000 0,06384157 0,12298064 ! phospholipid efflux GO:0033700 16 10 0,000 0,06384157 0,12288225 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06384157 0,12278403 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06384157 0,12268595 ! lung alveolus development GO:0048286 26 10 0,000 0,06384157 0,12258804 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06384157 0,12249028 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06384157 0,12239268 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06384157 0,12229524 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06384157 0,12219794 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06384157 0,12210081 ! endoderm development GO:0007492 16 10 0,000 0,06384157 0,12200382 ! arginine catabolic process GO:0006527 13 10 0,000 0,06384157 0,121907 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06384157 0,12181032 ! proline metabolic process GO:0006560 13 10 0,000 0,06384157 0,1217138 ! L-serine metabolic process GO:0006563 18 10 0,000 0,06384157 0,12161743 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06384157 0,12152121 ! V(D)J recombination GO:0033151 28 10 0,000 0,06384157 0,12142515 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06384157 0,12132924 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06384157 0,12123348 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06384157 0,12113787 ! B cell proliferation GO:0042100 18 10 0,000 0,06384157 0,12104241 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06384157 0,1209471 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06384157 0,12085194 ! multicellular organism growth GO:0035264 18 10 0,000 0,06384157 0,12075693 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06384157 0,12066207 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06384157 0,12056736 ! epithelial cell development GO:0002064 20 10 0,000 0,06384157 0,1204728 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06384157 0,12037838 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06384157 0,12028412 ! macroautophagy GO:0016236 17 10 0,000 0,06384157 0,12019 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06384157 0,12009602 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06384157 0,1200022 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06384157 0,11990852 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,06384157 0,11981499 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06384157 0,1197216 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06384157 0,11962836 ! brain morphogenesis GO:0048854 23 10 0,000 0,06384157 0,11953527 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06384157 0,11944231 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06384157 0,11934951 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06384157 0,11925684 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06384157 0,11916433 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06384157 0,11907195 ! DNA ligation GO:0006266 19 10 0,000 0,06384157 0,11897972 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06384157 0,11888763 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06384157 0,11879568 ! melanosome localization GO:0032400 16 10 0,000 0,06384157 0,11870388 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06384157 0,11861221 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06384157 0,11852069 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06384157 0,11842931 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06384157 0,11833807 ! mRNA cleavage GO:0006379 17 10 0,000 0,06384157 0,11824697 ! protein sumoylation GO:0016925 15 10 0,000 0,06384157 0,11815601 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06384157 0,11806519 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06384157 0,11797451 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06384157 0,11788397 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06384157 0,11779357 ! salivary gland development GO:0007431 27 10 0,000 0,06384157 0,11770331 ! prophase GO:0051324 15 10 0,000 0,06384157 0,11761318 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06384157 0,11752319 ! apical protein localization GO:0045176 15 10 0,000 0,06384157 0,11743335 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06384157 0,11734363 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06384157 0,11725406 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,06384157 0,11716462 ! midbrain development GO:0030901 13 10 0,000 0,06384157 0,11707532 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06384157 0,11698615 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06384157 0,11689712 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06384157 0,11680822 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06384157 0,11671946 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06384157 0,11663084 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06384157 0,11654235 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06384157 0,11645399 ! detection of calcium ion GO:0005513 23 10 0,000 0,06384157 0,11636577 ! oocyte development GO:0048599 17 10 0,000 0,06384157 0,11627768 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06384157 0,11618972 ! blastocyst formation GO:0001825 17 10 0,000 0,06384157 0,1161019 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06384157 0,11601421 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06384157 0,11592665 ! activation of innate immune response GO:0002218 12 10 0,000 0,06384157 0,11583923 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06384157 0,11575193 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06384157 0,11566477 ! response to nicotine GO:0035094 20 10 0,000 0,06384157 0,11557774 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06384157 0,11549084 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06384157 0,11540407 ! localization within membrane GO:0051668 20 10 0,000 0,06384157 0,11531743 ! regulation of mitosis GO:0007088 105 63 1,000 0,06469403 0,11676957 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,06469403 0,11668204 ! germ cell development GO:0007281 118 65 1,000 0,06832396 0,12313667 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06999826 0,12605973 ! respiratory burst GO:0045730 17 11 0,000 0,06999826 0,12596545 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06999826 0,1258713 ! neuron fate specification GO:0048665 17 11 0,000 0,06999826 0,1257773 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06999826 0,12568344 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06999826 0,12558971 GO:0046579|positive regulation of Ras protein signal transduction, ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06999826 0,12549613 ! response to pain GO:0048265 24 11 0,000 0,06999826 0,12540268 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06999826 0,12530938 ! T cell proliferation GO:0042098 26 11 0,000 0,06999826 0,12521621 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06999826 0,12512318 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06999826 0,12503029 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,06999826 0,12493754 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06999826 0,12484493 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06999826 0,12475245 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06999826 0,12466011 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06999826 0,1245679 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06999826 0,12447583 ! syncytium formation GO:0006949 18 11 0,000 0,06999826 0,1243839 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06999826 0,12429211 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06999826 0,12420045 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06999826 0,12410892 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06999826 0,12401753 ! lipid digestion GO:0044241 18 11 0,000 0,06999826 0,12392627 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06999826 0,12383515 ! UV protection GO:0009650 19 11 0,000 0,06999826 0,12374416 ! adult heart development GO:0007512 14 11 0,000 0,06999826 0,12365331 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06999826 0,12356259 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06999826 0,123472 ! temperature homeostasis GO:0001659 17 11 0,000 0,06999826 0,12338154 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06999826 0,12329122 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06999826 0,12320103 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06999826 0,12311097 ! regulation of organ growth GO:0046620 13 11 0,000 0,06999826 0,12302104 ! pigment granule localization GO:0051875 20 11 0,000 0,06999826 0,12293124 ! vasoconstriction GO:0042310 18 11 0,000 0,06999826 0,12284158 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06999826 0,12275204 ! embryonic axis specification GO:0000578 18 11 0,000 0,06999826 0,12266264 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06999826 0,12257337 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06999826 0,12248422 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06999826 0,12239521 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06999826 0,12230632 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06999826 0,12221756 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06999826 0,12212894 ! zymogen activation GO:0031638 15 11 0,000 0,06999826 0,12204044 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06999826 0,12195207 ! nucleosome positioning GO:0016584 15 11 0,000 0,06999826 0,12186382 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06999826 0,12177571 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06999826 0,12168772 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06999826 0,12159986 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06999826 0,12151212 ! acid secretion GO:0046717 18 11 0,000 0,06999826 0,12142452 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06999826 0,12133703 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06999826 0,12124968 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06999826 0,12116245 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06999826 0,12107534 ! oocyte differentiation GO:0009994 18 11 0,000 0,06999826 0,12098836 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06999826 0,12090151 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06999826 0,12081478 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06999826 0,12072817 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06999826 0,12064169 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06999826 0,12055534 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,06999826 0,1204691 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06999826 0,12038299 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06999826 0,120297 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06999826 0,12021114 ! defense response to fungus GO:0050832 13 11 0,000 0,06999826 0,1201254 ! developmental induction GO:0031128 19 11 0,000 0,06999826 0,12003977 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06999826 0,11995428 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06999826 0,1198689 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06999826 0,11978364 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06999826 0,11969851 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06999826 0,1196135 ! nucleus localization GO:0051647 19 11 0,000 0,06999826 0,1195286 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06999826 0,11944383 ! extracellular matrix organization GO:0030198 133 66 1,000 0,07016369 0,11964128 ! secondary metabolic process GO:0019748 116 66 1,000 0,07016369 0,11955654 ! developmental maturation GO:0021700 116 66 1,000 0,07016369 0,11947193 ! cell projection assembly GO:0030031 120 66 1,000 0,07016369 0,11938744 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,07201954 0,12245867 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,07201954 0,12237219 ! chromosome segregation GO:0007059 113 67 1,000 0,07201954 0,12228583 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,07201954 0,12219959 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,07201954 0,12211347 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,07389122 0,12519879 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,07389122 0,12511068 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,07389122 0,1250227 ! negative regulation of cell size GO:0045792 134 69 1,000 0,07577845 0,12812575 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,07577845 0,12803578 ! urogenital system development GO:0001655 137 69 1,000 0,07577845 0,12794593 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,07577845 0,12785621 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07611466 0,12833347 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07611466 0,1282436 ! virus-host interaction GO:0019048 29 12 0,000 0,07611466 0,12815386 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,07611466 0,12806424 ! cartilage condensation GO:0001502 20 12 0,000 0,07611466 0,12797475 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,07611466 0,12788538 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,07611466 0,12779614 ! protein complex disassembly GO:0043241 27 12 0,000 0,07611466 0,12770702 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07611466 0,12761802 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07611466 0,12752915 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07611466 0,12744041 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07611466 0,12735178 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07611466 0,12726328 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07611466 0,1271749 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07611466 0,12708665 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07611466 0,12699852 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07611466 0,12691051 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07611466 0,12682262 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07611466 0,12673485 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07611466 0,12664721 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07611466 0,12655968 ! forebrain cell migration GO:0021885 21 12 0,000 0,07611466 0,12647228 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07611466 0,126385 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07611466 0,12629784 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07611466 0,12621079 ! entry into host cell GO:0030260 32 12 0,000 0,07611466 0,12612387 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,07611466 0,12603707 ! monoamine transport GO:0015844 18 12 0,000 0,07611466 0,12595039 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07611466 0,12586382 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07611466 0,12577738 GO:0015800|acidic amino acid transport, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07611466 0,12569105 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07611466 0,12560484 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07611466 0,12551875 ! protein homotetramerization GO:0051289 21 12 0,000 0,07611466 0,12543278 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07611466 0,12534693 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07611466 0,12526119 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07611466 0,12517557 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07611466 0,12509007 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07611466 0,12500468 ! cranial nerve development GO:0021545 20 12 0,000 0,07611466 0,12491942 ! fucose catabolic process GO:0019317 22 12 0,000 0,07611466 0,12483426 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07611466 0,12474923 ! histone acetylation GO:0016573 26 12 0,000 0,07611466 0,1246643 ! histone methylation GO:0016571 26 12 0,000 0,07611466 0,1245795 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07611466 0,12449481 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,07611466 0,12441023 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07611466 0,12432577 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07611466 0,12424143 ! spleen development GO:0048536 22 12 0,000 0,07611466 0,1241572 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07611466 0,12407308 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07611466 0,12398907 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07611466 0,12390518 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07611466 0,12382141 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07611466 0,12373775 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,07611466 0,1236542 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07611466 0,12357076 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07611466 0,12348743 ! response to cold GO:0009409 17 12 0,000 0,07611466 0,12340422 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07611466 0,12332112 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07611466 0,12323813 ! regulation of immune effector process GO:0002697 137 71 1,000 0,07959841 0,12879204 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,08153058 0,13182969 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,08153058 0,13174116 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,08153058 0,13165274 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,08153058 0,13156444 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08219103 0,1325413 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08219103 0,13245253 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08219103 0,13236387 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,08219103 0,13227533 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08219103 0,13218691 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,08219103 0,13209861 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,08219103 0,13201043 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08219103 0,13192236 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,08219103 0,13183442 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08219103 0,13174658 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08219103 0,13165887 ! methionine metabolic process GO:0006555 27 13 0,000 0,08219103 0,13157127 ! plasma membrane organization GO:0007009 24 13 0,000 0,08219103 0,13148379 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,08219103 0,13139643 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08219103 0,13130918 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,08219103 0,13122205 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,08219103 0,13113503 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,08219103 0,13104813 ! response to X-ray GO:0010165 25 13 0,000 0,08219103 0,13096134 ! cytokine metabolic process GO:0042107 22 13 0,000 0,08219103 0,13087467 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,08219103 0,13078811 ! exocrine system development GO:0035272 32 13 0,000 0,08219103 0,13070167 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,08219103 0,13061534 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08219103 0,13052912 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08219103 0,13044302 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,08219103 0,13035704 ! regulation of DNA repair GO:0006282 21 13 0,000 0,08219103 0,13027116 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,08219103 0,1301854 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,08219103 0,13009975 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08219103 0,13001422 ! regulation of cellular pH GO:0030641 22 13 0,000 0,08219103 0,12992879 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08219103 0,12984348 ! ribosome assembly GO:0042255 17 13 0,000 0,08219103 0,12975828 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08219103 0,1296732 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08219103 0,12958822 ! chromatin silencing GO:0006342 26 13 0,000 0,08219103 0,12950336 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,08219103 0,1294186 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08219103 0,12933396 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08219103 0,12924943 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,08219103 0,12916501 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08219103 0,12908069 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,08219103 0,12899649 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08219103 0,1289124 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,08219103 0,12882842 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08219103 0,12874455 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08219103 0,12866078 ! insulin secretion GO:0030073 23 13 0,000 0,08219103 0,12857713 ! acrosome reaction GO:0007340 18 13 0,000 0,08219103 0,12849358 ! neurotransmitter transport GO:0006836 123 74 1,000 0,08543796 0,13348294 ! meiosis GO:0007126 121 74 1,000 0,08543796 0,13339632 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 1,000 0,08543796 0,13330981 ! eye development GO:0001654 143 74 1,000 0,08543796 0,13322342 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,08741262 0,13621423 ! meiotic cell cycle GO:0051321 122 75 1,000 0,08741262 0,13612606 ! rRNA transcription GO:0009303 25 14 0,000 0,08822764 0,13730641 ! lactation GO:0007595 26 14 0,000 0,08822764 0,13721766 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,08822764 0,13712901 ! reproductive cellular process GO:0048610 20 14 0,000 0,08822764 0,13704049 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08822764 0,13695207 ! regulation of S phase GO:0033261 23 14 0,000 0,08822764 0,13686377 ! water transport GO:0006833 21 14 0,000 0,08822764 0,13677559 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08822764 0,13668752 ! non-recombinational repair GO:0000726 25 14 0,000 0,08822764 0,13659956 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08822764 0,13651171 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08822764 0,13642398 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08822764 0,13633636 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08822764 0,13624885 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08822764 0,13616146 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08822764 0,13607417 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08822764 0,135987 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08822764 0,13589994 ! arginine metabolic process GO:0006525 17 14 0,000 0,08822764 0,135813 ! regulation of heart rate GO:0002027 24 14 0,000 0,08822764 0,13572616 ! organic alcohol transport GO:0015850 29 14 0,000 0,08822764 0,13563943 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,08822764 0,13555282 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08822764 0,13546631 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,08822764 0,13537992 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08822764 0,13529363 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08822764 0,13520746 ! L-amino acid transport GO:0015807 30 14 0,000 0,08822764 0,1351214 ! bone mineralization GO:0030282 17 14 0,000 0,08822764 0,13503544 ! stem cell development GO:0048864 43 14 0,000 0,08822764 0,13494959 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08822764 0,13486386 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08822764 0,13477823 ! cerebellum development GO:0021549 21 14 0,000 0,08822764 0,13469271 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08822764 0,1346073 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08822764 0,134522 ! response to gamma radiation GO:0010332 28 14 0,000 0,08822764 0,1344368 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08822764 0,13435172 ! cofactor transport GO:0051181 26 14 0,000 0,08822764 0,13426674 ! NADP metabolic process GO:0006739 24 14 0,000 0,08822764 0,13418187 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08822764 0,1340971 ! intestinal absorption GO:0050892 25 14 0,000 0,08822764 0,13401244 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08822764 0,13392789 ! oxygen transport GO:0015671 21 14 0,000 0,08822764 0,13384345 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08822764 0,13375911 ! male genitalia development GO:0030539 24 14 0,000 0,08822764 0,13367488 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08822764 0,13359076 ! regulation of axon extension GO:0030516 37 14 0,000 0,08822764 0,13350674 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,08822764 0,13342282 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08822764 0,13333902 ! defense response to bacterium GO:0042742 89 76 1,000 0,08940091 0,13502736 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,09140256 0,13796397 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,09341732 0,14091666 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,09341732 0,14082837 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09422475 0,14195664 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09422475 0,14186781 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,09422475 0,14177908 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,09422475 0,14169047 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,09422475 0,14160197 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,09422475 0,14151358 ! copper ion transport GO:0006825 20 15 0,000 0,09422475 0,1414253 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,09422475 0,14133713 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,09422475 0,14124907 ! sulfate transport GO:0008272 23 15 0,000 0,09422475 0,14116112 ! response to cAMP GO:0051591 22 15 0,000 0,09422475 0,14107328 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,09422475 0,14098554 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,09422475 0,14089792 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,09422475 0,14081041 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,09422475 0,140723 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,09422475 0,1406357 ! response to hexose stimulus GO:0009746 22 15 0,000 0,09422475 0,14054851 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,09422475 0,14046143 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,09422475 0,14037446 ! pituitary gland development GO:0021983 29 15 0,000 0,09422475 0,14028759 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,09422475 0,14020084 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,09422475 0,14011419 ! regulation of exocytosis GO:0017157 22 15 0,000 0,09422475 0,14002764 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,09422475 0,13994121 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,09422475 0,13985488 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,09422475 0,13976865 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,09422475 0,13968253 ! histone deacetylation GO:0016575 20 15 0,000 0,09422475 0,13959652 ! mRNA splice site selection GO:0006376 38 15 0,000 0,09422475 0,13951062 ! tissue regeneration GO:0042246 26 15 0,000 0,09422475 0,13942482 ! water homeostasis GO:0030104 27 15 0,000 0,09422475 0,13933912 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09422475 0,13925353 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,09422475 0,13916805 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,09422475 0,13908267 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,09422475 0,1389974 ! dopamine metabolic process GO:0042417 35 15 0,000 0,09422475 0,13891223 ! heme biosynthetic process GO:0006783 29 15 0,000 0,09422475 0,13882716 ! detection of bacterium GO:0016045 18 15 0,000 0,09422475 0,1387422 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,09422475 0,13865734 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,09422475 0,13857259 ! peptide hormone processing GO:0016486 23 15 0,000 0,09422475 0,13848794 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,09544493 0,14019567 ! T cell activation GO:0042110 168 81 1,000 0,09953768 0,14611816 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,09953768 0,14602906 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,09953768 0,14594007 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,10018261 0,1467962 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,10018261 0,14670686 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,10018261 0,14661762 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,10018261 0,14652849 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,10018261 0,14643947 ! bone remodeling GO:0046849 27 16 0,000 0,10018261 0,14635056 ! filopodium assembly GO:0046847 32 16 0,000 0,10018261 0,14626175 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,10018261 0,14617305 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,10018261 0,14608446 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,10018261 0,14599598 ! startle response GO:0001964 28 16 0,000 0,10018261 0,14590761 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,10018261 0,14581934 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,10018261 0,14573118 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,10018261 0,14564312 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,10018261 0,14555517 ! protein polyubiquitination GO:0000209 34 16 0,000 0,10018261 0,14546733 ! glutamate metabolic process GO:0006536 22 16 0,000 0,10018261 0,14537959 ! response to osmotic stress GO:0006970 25 16 0,000 0,10018261 0,14529196 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,10018261 0,14520444 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,10018261 0,14511702 ! fructose metabolic process GO:0006000 25 16 0,000 0,10018261 0,1450297 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10018261 0,14494249 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10018261 0,14485539 ! intermediate filament-based process GO:0045103 32 16 0,000 0,10018261 0,14476839 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,10018261 0,14468149 ! negative regulation of immune response GO:0050777 35 16 0,000 0,10018261 0,1445947 ! axon cargo transport GO:0008088 43 16 0,000 0,10018261 0,14450801 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,10018261 0,14442143 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,10018261 0,14433495 ! DNA replication initiation GO:0006270 27 16 0,000 0,10018261 0,14424857 ! neuron recognition GO:0008038 35 16 0,000 0,10018261 0,1441623 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,10018261 0,14407613 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,10018261 0,14399006 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,10018261 0,1439041 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,10018261 0,14381824 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,10018261 0,14373248 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,10018261 0,14364682 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,10018261 0,14356127 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,10018261 0,14347581 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10018261 0,14339046 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,10018261 0,14330521 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,10018261 0,14322006 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,10018261 0,14313501 ! defense response to virus GO:0051607 37 16 0,000 0,10018261 0,14305007 ! response to drug GO:0042493 143 82 1,000 0,10160232 0,14499121 ! negative regulation of growth GO:0045926 155 84 1,000 0,10576691 0,15084481 ! regulation of ligase activity GO:0051340 142 84 1,000 0,10576691 0,15075545 ! metencephalon development GO:0022037 30 17 0,000 0,10610148 0,15114278 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10610148 0,15105335 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10610148 0,15096402 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10610148 0,1508748 ! endothelial cell migration GO:0043542 28 17 0,000 0,10610148 0,15078568 ! inositol metabolic process GO:0006020 28 17 0,000 0,10610148 0,15069667 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10610148 0,15060776 ! glial cell development GO:0021782 27 17 0,000 0,10610148 0,15051896 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10610148 0,15043027 ! adult walking behavior GO:0007628 33 17 0,000 0,10610148 0,15034167 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10610148 0,15025318 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10610148 0,1501648 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,10610148 0,15007652 ! myoblast differentiation GO:0045445 45 17 0,000 0,10610148 0,14998834 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10610148 0,14990027 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,10610148 0,1498123 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10610148 0,14972443 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10610148 0,14963667 ! glycine metabolic process GO:0006544 28 17 0,000 0,10610148 0,14954901 ! NAD metabolic process GO:0019674 29 17 0,000 0,10610148 0,14946145 ! DNA integration GO:0015074 29 17 0,000 0,10610148 0,149374 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,10610148 0,14928664 ! regulation of protein binding GO:0043393 33 17 0,000 0,10610148 0,14919939 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10610148 0,14911224 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10610148 0,1490252 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10610148 0,14893825 ! genitalia development GO:0048806 30 17 0,000 0,10610148 0,14885141 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,10610148 0,14876466 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10610148 0,14867802 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,10610148 0,14859148 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10610148 0,14850504 ! steroid catabolic process GO:0006706 31 17 0,000 0,10610148 0,1484187 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10610148 0,14833246 ! gas transport GO:0015669 25 17 0,000 0,10610148 0,14824632 ! organic cation transport GO:0015695 31 17 0,000 0,10610148 0,14816028 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10610148 0,14807434 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,10610148 0,1479885 ! microspike assembly GO:0030035 36 17 0,000 0,10610148 0,14790276 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,10610148 0,14781712 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,10610148 0,14773157 ! response to unfolded protein GO:0006986 131 85 1,000 0,10786638 0,15010209 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,10786638 0,15001532 ! tube morphogenesis GO:0035239 176 86 1,000 0,10997697 0,15286228 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,11198161 0,15555875 ! neuron maturation GO:0042551 42 18 0,000 0,11198161 0,15546899 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,11198161 0,15537933 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,11198161 0,15528977 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,11198161 0,15520032 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,11198161 0,15511097 ! memory GO:0007613 31 18 0,000 0,11198161 0,15502172 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11198161 0,15493258 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,11198161 0,15484354 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,11198161 0,1547546 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,11198161 0,15466576 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,11198161 0,15457702 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11198161 0,15448839 ! response to retinoic acid GO:0032526 26 18 0,000 0,11198161 0,15439986 ! response to fungus GO:0009620 21 18 0,000 0,11198161 0,15431143 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,11198161 0,1542231 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,11198161 0,15413487 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,11198161 0,15404674 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,11198161 0,15395872 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,11198161 0,15387079 ! vitamin transport GO:0051180 27 18 0,000 0,11198161 0,15378296 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,11198161 0,15369524 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,11198161 0,15360761 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,11198161 0,15352009 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,11198161 0,15343266 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,11198161 0,15334533 ! nerve development GO:0021675 28 18 0,000 0,11198161 0,15325811 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,11198161 0,15317098 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,11637319 0,15908744 ! protein secretion GO:0009306 39 19 0,000 0,11782325 0,16097828 ! positive regulation of translation GO:0045727 30 19 0,000 0,11782325 0,16088692 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11782325 0,16079566 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,11782325 0,16070451 ! skin development GO:0043588 36 19 0,000 0,11782325 0,16061345 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,11782325 0,16052251 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11782325 0,16043166 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,11782325 0,16034092 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,11782325 0,16025028 ! bile acid metabolic process GO:0008206 29 19 0,000 0,11782325 0,16015974 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11782325 0,16006931 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,11782325 0,15997898 ! cerebral cortex development GO:0021987 36 19 0,000 0,11782325 0,15988875 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,11782325 0,15979862 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,11782325 0,15970859 ! heme metabolic process GO:0042168 36 19 0,000 0,11782325 0,15961866 ! neuromuscular junction development GO:0007528 34 19 0,000 0,11782325 0,15952884 ! plasma membrane fusion GO:0045026 28 19 0,000 0,11782325 0,15943912 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,11782325 0,15934949 ! peptide cross-linking GO:0018149 37 19 0,000 0,11782325 0,15925997 ! protein export from nucleus GO:0006611 36 19 0,000 0,11782325 0,15917055 ! heart process GO:0003015 30 19 0,000 0,11782325 0,15908123 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,11782325 0,15899201 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,11782325 0,15890289 ! visual learning GO:0008542 36 19 0,000 0,11782325 0,15881386 ! cellular pigmentation GO:0033059 36 19 0,000 0,11782325 0,15872494 ! G1 phase GO:0051318 40 19 0,000 0,11782325 0,15863612 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11782325 0,1585474 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,11782325 0,15845877 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,11782325 0,15837025 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,11782325 0,15828182 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,11782325 0,1581935 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,11782325 0,15810527 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,11782325 0,15801714 ! cilium assembly GO:0042384 37 19 0,000 0,11782325 0,15792911 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11782325 0,15784117 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,11852597 0,15869421 ! response to protein stimulus GO:0051789 149 91 1,000 0,12068873 0,16150005 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,12068873 0,16141028 ! regulation of defense response GO:0031347 149 92 1,000 0,12286125 0,16422454 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,12362666 0,16515589 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,12362666 0,16506423 ! positive regulation of ossification GO:0045778 47 20 0,000 0,12362666 0,16497268 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,12362666 0,16488124 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,12362666 0,16478989 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,12362666 0,16469864 ! cAMP metabolic process GO:0046058 36 20 0,000 0,12362666 0,1646075 ! response to vitamin GO:0033273 31 20 0,000 0,12362666 0,16451645 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,12362666 0,16442551 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,12362666 0,16433467 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,12362666 0,16424393 ! response to alkaloid GO:0043279 38 20 0,000 0,12362666 0,16415328 ! retinoid metabolic process GO:0001523 32 20 0,000 0,12362666 0,16406274 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,12362666 0,1639723 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,12362666 0,16388196 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,12362666 0,16379171 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,12362666 0,16370157 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,12362666 0,16361152 ! body fluid secretion GO:0007589 31 20 0,000 0,12362666 0,16352158 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,12362666 0,16343173 ! peptide secretion GO:0002790 35 20 0,000 0,12362666 0,16334198 ! stem cell differentiation GO:0048863 53 20 0,000 0,12362666 0,16325233 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,12362666 0,16316278 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,12362666 0,16307333 ! sensory perception of pain GO:0019233 30 20 0,000 0,12362666 0,16298397 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,12362666 0,16289471 ! diencephalon development GO:0021536 34 20 0,000 0,12362666 0,16280556 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,12362666 0,16271649 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,12362666 0,16262753 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,12362666 0,16253866 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,12362666 0,16244989 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,12362666 0,16236122 ! regulation of glucose import GO:0046324 29 20 0,000 0,12362666 0,16227264 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,12362666 0,16218416 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,12362666 0,16209578 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,12362666 0,16200749 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,12362666 0,1619193 ! negative regulation of translation GO:0017148 29 20 0,000 0,12362666 0,1618312 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,12362666 0,1617432 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,12362666 0,1616553 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,1250433 0,1634189 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,1250433 0,16333018 ! regulation of membrane potential GO:0042391 164 93 1,000 0,1250433 0,16324156 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,1250433 0,16315303 ! female pregnancy GO:0007565 164 94 1,000 0,12723468 0,16592229 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12939208 0,16864429 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12939208 0,16855298 ! hormone secretion GO:0046879 38 21 0,000 0,12939208 0,16846177 ! glycerol metabolic process GO:0006071 34 21 0,000 0,12939208 0,16837066 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12939208 0,16827965 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,12939208 0,16818874 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12939208 0,16809792 ! axis specification GO:0009798 38 21 0,000 0,12939208 0,16800721 ! ovarian follicle development GO:0001541 35 21 0,000 0,12939208 0,16791659 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12939208 0,16782607 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12939208 0,16773564 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,12939208 0,16764532 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12939208 0,16755509 ! cell aging GO:0007569 44 21 0,000 0,12939208 0,16746496 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,12939208 0,16737492 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,12939208 0,16728498 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,12939208 0,16719514 ! vasodilation GO:0042311 39 21 0,000 0,12939208 0,1671054 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12939208 0,16701575 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12939208 0,1669262 ! oogenesis GO:0048477 36 21 0,000 0,12939208 0,16683674 ! DNA modification GO:0006304 34 21 0,000 0,12939208 0,16674738 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,12939208 0,16665811 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12939208 0,16656894 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,12939208 0,16647987 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12939208 0,16639089 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12939208 0,16630201 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,12939208 0,16621322 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,12939208 0,16612452 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12939208 0,16603592 ! collagen catabolic process GO:0030574 28 21 0,000 0,12939208 0,16594742 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12939208 0,16585901 ! gut development GO:0048565 39 21 0,000 0,12939208 0,16577069 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,13511977 0,17301658 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,13511977 0,17292455 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,13511977 0,17283262 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,13511977 0,17274079 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,13511977 0,17264905 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,13511977 0,17255741 ! regeneration GO:0031099 41 22 0,000 0,13511977 0,17246587 ! keratinization GO:0031424 28 22 0,000 0,13511977 0,17237442 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,13511977 0,17228308 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,13511977 0,17219182 ! sensory perception of taste GO:0050909 28 22 0,000 0,13511977 0,17210067 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,13511977 0,17200961 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,13511977 0,17191865 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,13511977 0,17182778 ! vacuolar transport GO:0007034 36 22 0,000 0,13511977 0,17173701 ! lysosome organization GO:0007040 41 22 0,000 0,13511977 0,17164634 ! central nervous system neuron development GO:0021954 46 22 0,000 0,13511977 0,17155576 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,13511977 0,17146528 ! fucose metabolic process GO:0006004 39 22 0,000 0,13511977 0,17137489 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,13511977 0,1712846 ! ureteric bud development GO:0001657 43 22 0,000 0,13511977 0,1711944 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,13511977 0,1711043 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,13511977 0,17101429 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,13511977 0,17092438 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,13511977 0,17083456 ! sarcomere organization GO:0045214 30 22 0,000 0,13511977 0,17074483 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,13511977 0,1706552 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,13511977 0,17056567 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,13511977 0,17047623 ! protein stabilization GO:0050821 39 22 0,000 0,13511977 0,17038688 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,13832387 0,17433589 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,13832387 0,17424462 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,14056671 0,17697724 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,14080996 0,17719077 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,14080996 0,17709815 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,14080996 0,17700562 ! gluconeogenesis GO:0006094 33 23 0,000 0,14080996 0,17691319 ! viral genome replication GO:0019079 41 23 0,000 0,14080996 0,17682086 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,14080996 0,17672862 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,14080996 0,17663648 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,14080996 0,17654443 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,14080996 0,17645248 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,14080996 0,17636063 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,14080996 0,17626887 ! visual behavior GO:0007632 42 23 0,000 0,14080996 0,1761772 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,14080996 0,17608563 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,14080996 0,17599416 ! response to ethanol GO:0045471 46 23 0,000 0,14080996 0,17590278 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,14080996 0,1758115 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,14080996 0,17572031 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,14080996 0,17562922 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,14080996 0,17553822 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,14080996 0,17544731 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,14080996 0,1753565 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,14080996 0,17526578 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,14080996 0,17517516 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,14080996 0,17508463 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,14080996 0,17499419 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,14080996 0,17490385 ! fatty acid transport GO:0015908 44 23 0,000 0,14080996 0,1748136 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,14080996 0,17472345 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,14080996 0,17463338 ! hormone transport GO:0009914 40 23 0,000 0,14080996 0,17454341 ! cell-cell recognition GO:0009988 25 23 0,000 0,14080996 0,17445353 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,14080996 0,17436375 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,14080996 0,17427405 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,14080996 0,17418445 GO:0006099|tricarboxylic acid cycle, ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,1464629 0,18108414 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1464629 0,18099113 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,1464629 0,18089822 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1464629 0,18080541 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1464629 0,18071269 ! spinal cord development GO:0021510 47 24 0,000 0,1464629 0,18062006 ! vacuole organization GO:0007033 43 24 0,000 0,1464629 0,18052753 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,1464629 0,18043509 ! digestive system process GO:0022600 39 24 0,000 0,1464629 0,18034275 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,1464629 0,18025051 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,1464629 0,18015835 ! regulation of behavior GO:0050795 43 24 0,000 0,1464629 0,18006629 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,1464629 0,17997433 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,1464629 0,17988246 ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,1464629 0,17979068 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1464629 0,179699 ! pentose metabolic process GO:0019321 35 24 0,000 0,1464629 0,17960741 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1464629 0,17951591 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1464629 0,17942451 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1464629 0,1793332 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1464629 0,17924198 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1464629 0,17915086 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1464629 0,17905983 ! regulation of amine transport GO:0051952 40 24 0,000 0,1464629 0,17896889 ! protein tetramerization GO:0051262 52 24 0,000 0,1464629 0,17887804 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,15207884 0,18564266 ! myelination GO:0042552 45 25 0,000 0,15207884 0,18554852 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,15207884 0,18545448 ! phototransduction GO:0007602 33 25 0,000 0,15207884 0,18536053 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,15207884 0,18526667 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,15207884 0,18517291 ! sperm motility GO:0030317 31 25 0,000 0,15207884 0,18507925 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,15207884 0,18498568 ! chromosome condensation GO:0030261 45 25 0,000 0,15207884 0,18489221 ! response to starvation GO:0042594 42 25 0,000 0,15207884 0,18479883 ! osteoblast differentiation GO:0001649 60 25 0,000 0,15207884 0,18470554 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,15207884 0,18461235 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,15207884 0,18451925 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,15207884 0,18442625 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,15207884 0,18433334 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,15207884 0,18424052 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,15207884 0,1841478 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,15207884 0,18405517 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,15207884 0,18396263 ! immunoglobulin production GO:0002377 55 25 0,000 0,15207884 0,18387019 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,15207884 0,18377784 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,15207884 0,18368558 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,15207884 0,18359342 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,15207884 0,18350134 ! telomere organization GO:0032200 43 25 0,000 0,15207884 0,18340936 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,15207884 0,18331747 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,15765801 0,1899475 ! embryonic pattern specification GO:0009880 44 26 0,000 0,15765801 0,18985243 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,15765801 0,18975746 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,15765801 0,18966258 ! initiation of viral infection GO:0019059 57 26 0,000 0,15765801 0,1895678 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,15765801 0,18947311 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,15765801 0,18937851 ! tube lumen formation GO:0035148 50 26 0,000 0,15765801 0,18928401 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,15765801 0,18918961 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,15765801 0,1890953 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,15765801 0,18900108 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,15765801 0,18890695 GO:0045936|negative regulation of phosphate metabolic process, ! response to estradiol stimulus GO:0032355 40 26 0,000 0,15765801 0,18881292 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,15765801 0,18871899 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,15765801 0,18862514 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,15765801 0,18853139 ! blastocyst development GO:0001824 49 26 0,000 0,15765801 0,18843774 ! leukocyte proliferation GO:0070661 52 26 0,000 0,15765801 0,18834417 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,15765801 0,1882507 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,16320065 0,19477221 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,16320065 0,19467564 ! iron ion transport GO:0006826 59 27 0,000 0,16320065 0,19457917 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,16320065 0,1944828 ! protein amino acid acylation GO:0043543 55 27 0,000 0,16320065 0,19438652 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,16320065 0,19429033 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,16320065 0,19419425 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,16320065 0,19409825 ! autophagy GO:0006914 41 27 0,000 0,16320065 0,19400235 ! male gonad development GO:0008584 44 27 0,000 0,16320065 0,19390655 ! primary neural tube formation GO:0014020 51 27 0,000 0,16320065 0,19381084 ! base-excision repair GO:0006284 41 27 0,000 0,16320065 0,19371523 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,16320065 0,19361971 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,16320065 0,19352428 ! glutathione metabolic process GO:0006749 39 27 0,000 0,16320065 0,19342895 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,16320065 0,19333371 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,16320065 0,19323857 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,16320065 0,19314352 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,16870701 0,19956198 ! circadian rhythm GO:0007623 50 28 0,000 0,16870701 0,19946391 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,16870701 0,19936594 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,16870701 0,19926807 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,16870701 0,19917029 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16870701 0,19907261 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,16870701 0,19897503 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16870701 0,19887754 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16870701 0,19878015 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,16870701 0,19868285 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,16870701 0,19858565 ! synaptogenesis GO:0007416 42 28 0,000 0,16870701 0,19848854 ! lipid oxidation GO:0034440 43 28 0,000 0,16870701 0,19839152 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16870701 0,19829461 ! translational initiation GO:0006413 65 29 0,000 0,17417731 0,20462432 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,17417731 0,20452446 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,17417731 0,20442469 ! regulation of pH GO:0006885 43 29 0,000 0,17417731 0,20432502 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,17417731 0,20422545 ! catechol metabolic process GO:0009712 54 29 0,000 0,17417731 0,20412597 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,17417731 0,20402659 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,17417731 0,20392731 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,17417731 0,20382812 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,17417731 0,20372903 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,17417731 0,20363004 ! cell fate determination GO:0001709 60 29 0,000 0,17417731 0,20353114 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,17417731 0,20343234 ! detection of light stimulus GO:0009583 38 29 0,000 0,17417731 0,20333363 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,17417731 0,20323502 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,17417731 0,20313651 ! tissue homeostasis GO:0001894 48 29 0,000 0,17417731 0,20303809 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,1796118 0,20927167 ! zinc ion transport GO:0006829 45 30 0,000 0,1796118 0,20917037 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,1796118 0,20906918 ! myofibril assembly GO:0030239 47 30 0,000 0,1796118 0,20896808 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,1796118 0,20886708 ! phospholipid transport GO:0015914 51 30 0,000 0,1796118 0,20876618 ! ensheathment of neurons GO:0007272 57 30 0,000 0,1796118 0,20866538 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,1796118 0,20856467 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,1796118 0,20846406 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,1796118 0,20836355 ! eye morphogenesis GO:0048592 60 30 0,000 0,1796118 0,20826313 ! regulation of B cell activation GO:0050864 50 30 0,000 0,1796118 0,20816281 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,18501071 0,21431669 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,18501071 0,21421355 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,18501071 0,21411051 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,18501071 0,21400758 ! ovulation cycle process GO:0022602 49 31 0,000 0,18501071 0,21390474 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,18501071 0,213802 ! mesoderm formation GO:0001707 69 31 0,000 0,18501071 0,21369936 ! natural killer cell activation GO:0030101 45 31 0,000 0,18501071 0,21359681 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,18501071 0,21349437 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,18501071 0,21339202 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,18501071 0,21328977 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,18501071 0,21318762 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,19037426 0,21926303 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,19037426 0,21915812 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,19037426 0,21905331 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,19037426 0,2189486 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,19037426 0,21884399 ! spliceosome assembly GO:0000245 67 32 0,000 0,19037426 0,21873948 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,19037426 0,21863507 ! metanephros development GO:0001656 74 32 0,000 0,19037426 0,21853076 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,19037426 0,21842655 ! response to ionizing radiation GO:0010212 65 32 0,000 0,19037426 0,21832244 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,19037426 0,21821842 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,19037426 0,21811451 ! muscle cell development GO:0055001 49 32 0,000 0,19037426 0,2180107 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,19037426 0,21790698 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,19037426 0,21780336 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,19037426 0,21769984 ! ovulation cycle GO:0042698 51 32 0,000 0,19037426 0,21759642 ! peripheral nervous system development GO:0007422 64 32 0,000 0,19037426 0,2174931 ! BMP signaling pathway GO:0030509 64 32 0,000 0,19037426 0,21738988 ! hindbrain development GO:0030902 61 32 0,000 0,19037426 0,21728675 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,19037426 0,21718372 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,19037426 0,21708079 ! gene silencing GO:0016458 65 32 0,000 0,19037426 0,21697796 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,19570269 0,2229454 ! protein targeting to membrane GO:0006612 68 33 0,000 0,19570269 0,22283989 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,19570269 0,22273447 ! ceramide metabolic process GO:0006672 64 33 0,000 0,19570269 0,22262916 ! formation of primary germ layer GO:0001704 72 33 0,000 0,19570269 0,22252395 ! cell fate specification GO:0001708 52 33 0,000 0,19570269 0,22241884 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,19570269 0,22231382 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,19570269 0,22220891 ! adult locomotory behavior GO:0008344 59 33 0,000 0,19570269 0,22210409 ! glial cell differentiation GO:0010001 63 34 0,000 0,20099623 0,22800421 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,20099623 0,22789677 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,20099623 0,22778942 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,20099623 0,22768217 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,20099623 0,22757503 ! mismatch repair GO:0006298 46 34 0,000 0,20099623 0,22746799 ! spermatid development GO:0007286 63 34 0,000 0,20099623 0,22736104 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,20099623 0,2272542 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,20099623 0,22714746 ! regulation of muscle development GO:0048634 70 35 0,000 0,20625511 0,23298112 ! negative regulation of secretion GO:0051048 63 35 0,000 0,20625511 0,23287179 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,20625511 0,23276257 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,20625511 0,23265344 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,20625511 0,23254442 ! odontogenesis GO:0042476 66 35 0,000 0,20625511 0,2324355 ! female gonad development GO:0008585 58 35 0,000 0,20625511 0,23232668 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,20625511 0,23221797 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,20625511 0,23210935 ! cytokine production GO:0001816 59 35 0,000 0,20625511 0,23200084 ! neural tube formation GO:0001841 67 35 0,000 0,20625511 0,23189243 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,21147954 0,2376552 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,21147954 0,23754425 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,21147954 0,2374334 ! positive regulation of cell development GO:0010720 80 36 0,000 0,21147954 0,23732266 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,21147954 0,23721202 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,21147954 0,23710148 ! aerobic respiration GO:0009060 55 36 0,000 0,21147954 0,23699105 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,21147954 0,23688072 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,21147954 0,23677049 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,21147954 0,23666037 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,21666977 0,24235586 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,21666977 0,24224324 ! actomyosin structure organization GO:0031032 62 37 0,000 0,21666977 0,24213073 ! organic anion transport GO:0015711 68 37 0,000 0,21666977 0,24201832 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,21666977 0,24190601 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,21666977 0,24179381 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,21666977 0,24168171 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,21666977 0,24156972 ! pigment metabolic process GO:0042440 80 37 0,000 0,21666977 0,24145783 ! spermatid differentiation GO:0048515 66 37 0,000 0,21666977 0,24134605 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,221826 0,24697517 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,221826 0,24686094 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,221826 0,24674681 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,221826 0,24663278 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,221826 0,24651887 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,221826 0,24640505 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,221826 0,24629135 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,221826 0,24617774 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,221826 0,24606424 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,221826 0,24595085 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,221826 0,24583756 ! mRNA catabolic process GO:0006402 71 39 0,000 0,22694846 0,2513987 ! learning GO:0007612 77 39 0,000 0,22694846 0,25128301 ! ear morphogenesis GO:0042471 60 39 0,000 0,22694846 0,25116743 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,22694846 0,25105195 ! segmentation GO:0035282 67 39 0,000 0,22694846 0,25093657 ! ion transmembrane transport GO:0034220 66 39 0,000 0,22694846 0,25082131 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,22694846 0,25070614 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,22694846 0,25059109 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,23203736 0,25609261 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,23203736 0,25597519 ! feeding behavior GO:0007631 59 40 0,000 0,23203736 0,25585788 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,23709294 0,2613127 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,23709294 0,26119305 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,23709294 0,26107351 ! gliogenesis GO:0042063 88 41 0,000 0,23709294 0,26095408 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,23709294 0,26083476 ! T cell differentiation GO:0030217 81 41 0,000 0,23709294 0,26071555 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,23709294 0,26059644 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,23709294 0,26047745 ! female gamete generation GO:0007292 61 41 0,000 0,23709294 0,26035857 ! polyol metabolic process GO:0019751 66 41 0,000 0,23709294 0,26023979 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,23709294 0,26012112 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,2421154 0,26551033 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,2421154 0,26538937 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,2421154 0,26526852 ! regulation of tube size GO:0035150 71 42 0,000 0,2421154 0,26514778 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,2421154 0,26502714 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,2421154 0,26490662 ! neuron migration GO:0001764 79 42 0,000 0,2421154 0,26478621 ! regulation of protein secretion GO:0050708 71 42 0,000 0,2421154 0,26466591 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,24710497 0,26999753 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,24710497 0,26987497 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,24710497 0,26975252 ! neural tube development GO:0021915 77 43 0,000 0,24710497 0,26963018 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,24710497 0,26950796 ! striated muscle contraction GO:0006941 77 43 0,000 0,24710497 0,26938584 ! phagocytosis GO:0006909 90 43 0,000 0,24710497 0,26926384 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,24710497 0,26914194 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,25206185 0,27441666 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,25206185 0,27429254 ! male sex differentiation GO:0046661 76 44 0,000 0,25206185 0,27416854 ! double-strand break repair GO:0006302 81 44 0,000 0,25206185 0,27404465 ! biopolymer methylation GO:0043414 84 44 0,000 0,25206185 0,27392087 ! B cell differentiation GO:0030183 107 44 0,000 0,25206185 0,27379721 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,25698626 0,27902028 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,25698626 0,27889442 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,25698626 0,27876868 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,25698626 0,27864305 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,25698626 0,27851754 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,25698626 0,27839214 ! cell growth GO:0016049 84 45 0,000 0,25698626 0,27826685 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,26187841 0,28343655 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,26187841 0,2833091 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,26187841 0,28318177 ! response to calcium ion GO:0051592 81 47 0,000 0,26673851 0,28830766 ! endosome transport GO:0016197 108 47 0,000 0,26673851 0,2881782 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,26673851 0,28804886 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,26673851 0,28791963 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,26673851 0,28779052 ! methylation GO:0032259 90 47 0,000 0,26673851 0,28766152 ! Notch signaling pathway GO:0007219 96 48 0,000 0,27156677 0,2927373 ! cellular component disassembly GO:0022411 86 48 0,000 0,27156677 0,2926062 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,27156677 0,29247522 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,27156677 0,29234436 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,27156677 0,29221362 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,27156677 0,29208299 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,27156677 0,29195248 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2763634 0,29697648 ! regulation of action potential GO:0001508 95 49 0,000 0,2763634 0,2968439 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,2763634 0,29671144 ! regulation of ion transport GO:0043269 77 49 0,000 0,2763634 0,29657909 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,2763634 0,29644687 ! peptide metabolic process GO:0006518 76 49 0,000 0,2763634 0,29631476 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2763634 0,29618277 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2763634 0,2960509 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,2763634 0,29591915 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,2763634 0,29578751 ! neuromuscular process GO:0050905 99 50 0,000 0,2811286 0,30075385 ! regulation of ossification GO:0030278 117 50 0,000 0,2811286 0,30062018 ! inner ear development GO:0048839 79 50 0,000 0,2811286 0,30048663 ! histone modification GO:0016570 91 50 0,000 0,2811286 0,3003532 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,2811286 0,30021988 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,2811286 0,30008669 ! positive regulation of binding GO:0051099 78 51 0,000 0,28586257 0,30500459 ! viral infectious cycle GO:0019058 99 51 0,000 0,28586257 0,30486939 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,28586257 0,30473432 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,28586257 0,30459936 ! chromatin remodeling GO:0006338 109 51 0,000 0,28586257 0,30446452 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,28586257 0,3043298 ! covalent chromatin modification GO:0016569 101 52 0,000 0,29056553 0,30919977 ! synapse organization GO:0050808 85 52 0,000 0,29056553 0,30906308 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,29523768 0,31389388 ! RNA catabolic process GO:0006401 93 53 0,000 0,29523768 0,31375524 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,29523768 0,31361671 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,29523768 0,31347831 ! cell maturation GO:0048469 100 53 0,000 0,29523768 0,31334003 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,29523768 0,31320188 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,29987921 0,31798562 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,29987921 0,31784554 ! cell recognition GO:0008037 85 54 0,000 0,29987921 0,31770558 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,29987921 0,31756575 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,29987921 0,31742603 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,29987921 0,31728645 ! chloride transport GO:0006821 90 55 0,000 0,30449032 0,32202361 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,30449032 0,32188212 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,30449032 0,32174076 ! aging GO:0007568 103 55 0,000 0,30449032 0,32159952 ! gastrulation GO:0007369 112 55 0,000 0,30449032 0,32145841 ! RNA elongation GO:0006354 79 55 0,000 0,30449032 0,32131742 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,30449032 0,32117655 ! sensory perception of smell GO:0007608 80 56 0,000 0,30907122 0,32586562 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,30907122 0,32572289 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,30907122 0,32558028 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,30907122 0,32543779 ! regulation of DNA replication GO:0006275 101 56 0,000 0,30907122 0,32529543 ! proton transport GO:0015992 94 56 0,000 0,30907122 0,32515319 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,3136221 0,32979666 ! muscle fiber development GO:0048747 112 57 0,000 0,3136221 0,32965258 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,3136221 0,32950863 ! hydrogen transport GO:0006818 97 58 0,000 0,31814315 0,3341128 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,31814315 0,33396702 ! adult behavior GO:0030534 99 58 0,000 0,31814315 0,33382138 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,31814315 0,33367586 ! positive regulation of secretion GO:0051047 95 59 0,000 0,32263457 0,33823912 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,32263457 0,3380918 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,32263457 0,33794461 ! DNA catabolic process GO:0006308 86 59 0,000 0,32263457 0,33779755 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,32263457 0,33765062 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,32709656 0,34217144 ! regulation of heart contraction GO:0008016 110 60 0,000 0,32709656 0,34202273 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,32709656 0,34187416 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,3315293 0,3463567 ! mesoderm development GO:0007498 119 61 0,000 0,3315293 0,34620637 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,3315293 0,34605618 ! ear development GO:0043583 103 62 0,000 0,33593298 0,35050076 ! viral reproductive process GO:0022415 126 62 0,000 0,33593298 0,35034883 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,33593298 0,35019703 ! gonad development GO:0008406 98 62 0,000 0,33593298 0,35004537 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,3403078 0,35445047 ! detection of external stimulus GO:0009581 91 63 0,000 0,3403078 0,35429709 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,3403078 0,35414385 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,3403078 0,35399074 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,34465395 0,3583567 ! cell redox homeostasis GO:0045454 102 64 0,000 0,34465395 0,3582019 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,34465395 0,35804724 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,34465395 0,35789271 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,34897161 0,36221988 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,34897161 0,36206368 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,34897161 0,36190762 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,34897161 0,36175169 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,35326096 0,36604042 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,35326096 0,36588285 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,35752219 0,370137 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,35752219 0,3699778 ! lung development GO:0030324 144 67 0,000 0,35752219 0,36981874 ! amino acid transport GO:0006865 125 68 0,000 0,36175549 0,37403683 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,36175549 0,37387616 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,36175549 0,37371563 ! viral reproduction GO:0016032 134 68 0,000 0,36175549 0,37355524 ! regulation of lipase activity GO:0060191 130 68 0,000 0,36175549 0,37339498 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,36596103 0,37757386 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,36596103 0,37741202 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,36596103 0,37725032 ! antigen processing and presentation GO:0019882 104 69 0,000 0,36596103 0,37708876 ! appendage morphogenesis GO:0035107 135 70 0,000 0,37013901 0,3812305 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,37013901 0,38106737 ! amine catabolic process GO:0009310 117 71 0,000 0,37428959 0,38517568 ! reproductive structure development GO:0048608 113 71 0,000 0,37428959 0,38501101 ! appendage development GO:0048736 136 71 0,000 0,37428959 0,38484647 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,37428959 0,38468208 ! respiratory system development GO:0060541 153 72 0,000 0,37841295 0,38875387 ! learning or memory GO:0007611 147 73 0,000 0,38250928 0,39279442 ! regulation of blood pressure GO:0008217 125 73 0,000 0,38250928 0,39262685 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,38250928 0,39245942 ! axon guidance GO:0007411 139 73 0,000 0,38250928 0,39229213 ! fertilization GO:0009566 90 73 0,000 0,38250928 0,39212498 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,38657875 0,39612797 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,38657875 0,39595934 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,39062154 0,39992997 ! rhythmic process GO:0048511 128 75 0,000 0,39062154 0,39975986 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,39062154 0,39958989 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,39463781 0,40352681 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,39463781 0,40335539 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,39463781 0,40318411 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,39862775 0,40708759 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,40259152 0,41096105 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,4065293 0,41480471 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,4065293 0,41462887 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,41044125 0,41844138 ! response to metal ion GO:0010038 140 80 0,000 0,41044125 0,41826415 ! muscle cell differentiation GO:0042692 159 80 0,000 0,41044125 0,41808707 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,41044125 0,41791014 ! inorganic anion transport GO:0015698 138 80 0,000 0,41044125 0,41773335 ! digestion GO:0007586 112 81 0,000 0,41432755 0,42151039 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,41818835 0,42525831 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,41818835 0,42507865 ! response to nutrient GO:0007584 125 82 0,000 0,41818835 0,42489914 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,41818835 0,42471979 ! regulation of lyase activity GO:0051339 160 83 0,000 0,42202383 0,42843432 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,42583416 0,4321202 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,42583416 0,43193802 ! nucleosome assembly GO:0006334 122 85 0,000 0,42961949 0,43559397 ! amine biosynthetic process GO:0009309 138 86 0,000 0,43337999 0,43922167 ! response to inorganic substance GO:0010035 153 86 0,000 0,43337999 0,43903674 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,43337999 0,43885196 ! chromatin assembly GO:0031497 124 86 0,000 0,43337999 0,43866733 ! amine transport GO:0015837 155 86 0,000 0,43337999 0,43848286 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,43711582 0,44207678 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,43711582 0,44189104 ! cellular respiration GO:0045333 135 88 0,000 0,44082714 0,44545574 ! regulation of neurological system process GO:0031644 148 88 0,000 0,44082714 0,44526873 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,44082714 0,44508188 ! cellular defense response GO:0006968 114 89 0,000 0,44451412 0,44861618 ! ossification GO:0001503 188 90 0,000 0,44817691 0,45212312 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,44817691 0,45193363 ! sex differentiation GO:0007548 145 90 0,000 0,44817691 0,4517443 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,44817691 0,45155513 ! bone development GO:0060348 189 91 0,000 0,45181567 0,45503076 ! sterol metabolic process GO:0016125 152 91 0,000 0,45181567 0,45484037 ! nucleosome organization GO:0034728 138 92 0,000 0,45543055 0,45828771 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,45543055 0,45809611 ! vitamin metabolic process GO:0006766 139 92 0,000 0,45543055 0,45790468 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,45902172 0,46132258 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,46258932 0,46471395 ! transcription initiation GO:0006352 153 94 0,000 0,46258932 0,46451999 ! leukocyte differentiation GO:0002521 202 96 0,000 0,46965445 0,47141786 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,46965445 0,47122127 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! detection of stimulus GO:0051606 151 96 0,000 0,46965445 0,47102485 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,47315228 0,47433516 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,47315228 0,4741376 ! hormone metabolic process GO:0042445 157 97 0,000 0,47315228 0,47394021 ! response to virus GO:0009615 160 98 0,000 0,47662716 0,4772222 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,47662716 0,47702369 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,47662716 0,47682534 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,48007923 0,48007923