pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1302-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of actin filament polymerization GO:0030838 11 6 4,000 4,508E-11 1,101E-07 ! positive regulation of protein polymerization GO:0032273 27 14 5,000 1,281E-10 1,564E-07 ! positive regulation of protein complex assembly GO:0031334 34 18 5,000 7,76E-10 6,319E-07 ! positive regulation of cytoskeleton organization GO:0051495 52 24 5,000 5,459E-09 3,334E-06 ! positive regulation of organelle organization GO:0010638 108 58 6,000 6,023E-08 2,943E-05 ! negative regulation of endocytosis GO:0045806 12 9 3,000 1,572E-07 6,401E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 3,000 1,572E-07 5,487E-05 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 5,000 1,006E-06 3,073E-04 ! regulation of protein polymerization GO:0032271 117 55 5,000 1,006E-06 2,732E-04 ! regulation of actin filament length GO:0030832 118 58 5,000 1,384E-06 3,382E-04 ! regulation of cellular component size GO:0032535 125 61 5,000 1,871E-06 4,155E-04 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 2,000 2,133E-06 4,342E-04 ! regulation of protein complex assembly GO:0043254 132 63 5,000 2,266E-06 4,259E-04 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 2,000 4,247E-06 7,411E-04 ! regulation of actin cytoskeleton organization GO:0032956 167 76 5,000 6,833E-06 1,113E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 7,056E-06 1,077E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 2,000 7,399E-06 1,063E-03 ! regulation of actin filament polymerization GO:0030833 99 46 4,000 8,465E-06 1,149E-03 ! regulation of actin filament-based process GO:0032970 170 79 5,000 8,558E-06 1,1E-03 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 3,000 1,034E-05 1,263E-03 ! gas homeostasis GO:0033483 14 8 2,000 1,179E-05 1,371E-03 ! regulation of Rac protein signal transduction GO:0035020 18 8 2,000 1,179E-05 1,309E-03 ! liver development GO:0001889 55 25 3,000 1,463E-05 1,554E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 2,011E-05 2,047E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 3,000 2,011E-05 1,965E-03 ! ruffle organization GO:0031529 17 10 2,000 2,503E-05 2,352E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 2,503E-05 2,265E-03 ! regulation of endocytosis GO:0030100 104 60 4,000 3,15E-05 2,748E-03 ! cortical actin cytoskeleton organization GO:0030866 29 11 2,000 3,427E-05 2,887E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 3,427E-05 2,79E-03 ! positive regulation of catabolic process GO:0009896 72 32 3,000 4,025E-05 3,172E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 4,548E-05 3,472E-03 ! cortical cytoskeleton organization GO:0030865 30 12 2,000 4,548E-05 3,367E-03 ! mRNA polyadenylation GO:0006378 24 12 2,000 4,548E-05 3,268E-03 ! positive regulation of cell motion GO:0051272 157 65 4,000 4,649E-05 3,245E-03 ! folic acid and derivative biosynthetic process GO:0009396 25 13 2,000 5,887E-05 3,995E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 5,887E-05 3,887E-03 ! mRNA 3'-end processing GO:0031124 25 13 2,000 5,887E-05 3,785E-03 ! RNA polyadenylation GO:0043631 32 14 2,000 7,459E-05 4,672E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 8,032E-05 4,905E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 2,000 9,282E-05 5,531E-03 ! regulation of vesicle-mediated transport GO:0060627 136 77 4,000 1,049E-04 6,101E-03 ! cytokinesis GO:0000910 84 42 3,000 1,195E-04 6,79E-03 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 2,000 1,375E-04 7,634E-03 ! regulation of survival gene product expression GO:0045884 38 17 2,000 1,375E-04 7,465E-03 ! RNA 3'-end processing GO:0031123 37 17 2,000 1,375E-04 7,302E-03 ! positive regulation of proteolysis GO:0045862 36 18 2,000 1,643E-04 8,538E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,643E-04 8,36E-03 ! negative regulation of transport GO:0051051 164 85 4,000 1,675E-04 8,35E-03 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 1,675E-04 8,183E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 1,86E-04 8,911E-03 ! response to lipopolysaccharide GO:0032496 34 19 2,000 1,942E-04 9,124E-03 ! folic acid and derivative metabolic process GO:0006760 39 19 2,000 1,942E-04 8,951E-03 ! regulation of JAK-STAT cascade GO:0046425 76 48 3,000 2,02E-04 9,138E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 2,275E-04 0,0101032 ! endocrine system development GO:0035270 109 50 3,000 2,368E-04 0,01033165 ! positive regulation of growth GO:0045927 96 53 3,000 2,969E-04 0,01272553 ! positive regulation of protein catabolic process GO:0045732 44 22 2,000 3,045E-04 0,0128278 ! response to molecule of bacterial origin GO:0002237 40 23 2,000 3,487E-04 0,01443771 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 3,565E-04 0,01451632 ! adaptation of signaling pathway GO:0022401 7 5 1,000 3,565E-04 0,01427834 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 3,565E-04 0,01404805 ! positive regulation of glycolysis GO:0045821 13 5 1,000 3,565E-04 0,01382506 ! parathyroid gland development GO:0060017 14 5 1,000 3,565E-04 0,01360905 ! anagen GO:0042640 7 5 1,000 3,565E-04 0,01339968 ! valine metabolic process GO:0006573 12 5 1,000 3,565E-04 0,01319665 ! mRNA transcription GO:0009299 10 5 1,000 3,565E-04 0,01299969 ! positive regulation of filopodium assembly GO:0051491 16 5 1,000 3,565E-04 0,01280851 GO:0051489|regulation of filopodium assembly, ! response to food GO:0032094 6 5 1,000 3,565E-04 0,01262288 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 3,565E-04 0,01244256 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 3,565E-04 0,01226731 ! meiotic chromosome segregation GO:0045132 10 5 1,000 3,565E-04 0,01209693 ! positive regulation of chemokine production GO:0032722 8 5 1,000 3,565E-04 0,01193122 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 1,000 3,565E-04 0,01176999 ! regulation of muscle cell apoptosis GO:0010660 7 5 1,000 3,565E-04 0,01161305 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 1,000 3,565E-04 0,01146025 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 3,967E-04 0,01258706 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 3,967E-04 0,01242569 ! positive regulation of cell migration GO:0030335 137 58 3,000 4,202E-04 0,01299462 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 4,488E-04 0,01370616 ! regulation of transcription factor import into nucleus GO:0042990 58 26 2,000 5,051E-04 0,01523492 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 5,327E-04 0,01586928 ! protein refolding GO:0042026 15 6 1,000 5,327E-04 0,01567808 ! embryonic hemopoiesis GO:0035162 16 6 1,000 5,327E-04 0,01549144 ! toxin metabolic process GO:0009404 11 6 1,000 5,327E-04 0,01530919 ! T cell mediated immunity GO:0002456 17 6 1,000 5,327E-04 0,01513117 ! establishment of spindle localization GO:0051293 16 6 1,000 5,327E-04 0,01495725 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 5,327E-04 0,01478728 GO:0045686|negative regulation of glial cell differentiation, ! interaction with symbiont GO:0051702 14 6 1,000 5,327E-04 0,01462113 ! response to exogenous dsRNA GO:0043330 13 6 1,000 5,327E-04 0,01445868 ! hair follicle maturation GO:0048820 8 6 1,000 5,327E-04 0,01429979 ! oxygen homeostasis GO:0032364 10 6 1,000 5,327E-04 0,01414436 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 1,000 5,327E-04 0,01399227 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! receptor internalization GO:0031623 11 6 1,000 5,327E-04 0,01384341 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 1,000 5,327E-04 0,01369769 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 6,118E-04 0,01556996 ! vesicle docking GO:0048278 55 28 2,000 6,308E-04 0,01588815 ! group transfer coenzyme metabolic process GO:0006752 53 28 2,000 6,308E-04 0,01572602 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 6,489E-04 0,01601296 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 7,428E-04 0,01814563 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 7,428E-04 0,01796597 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 7,428E-04 0,01778983 ! microtubule nucleation GO:0007020 21 7 1,000 7,428E-04 0,01761711 ! vesicle fusion GO:0006906 20 7 1,000 7,428E-04 0,01744772 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 1,000 7,428E-04 0,01728155 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 7,428E-04 0,01711851 ! embryonic heart tube development GO:0035050 14 7 1,000 7,428E-04 0,01695853 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 7,428E-04 0,01680151 ! adaptive immune response GO:0002250 126 68 3,000 7,697E-04 0,01725011 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! complement activation, classical pathway GO:0006958 51 30 2,000 7,749E-04 0,0172102 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 7,749E-04 0,01705516 ! spindle organization GO:0007051 50 32 2,000 9,383E-04 0,02046775 ! positive regulation of T cell proliferation GO:0042102 60 32 2,000 9,383E-04 0,02028662 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 2,000 9,383E-04 0,02010867 ! regulation of protein import into nucleus GO:0042306 69 32 2,000 9,383E-04 0,01993381 ! actin filament organization GO:0007015 167 72 3,000 9,542E-04 0,02009668 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 1,000 9,864E-04 0,02059674 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 9,864E-04 0,02042219 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 9,864E-04 0,02025058 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 1,000 9,864E-04 0,02008182 ! oligopeptide transport GO:0006857 16 8 1,000 9,864E-04 0,01991586 ! succinate metabolic process GO:0006105 17 8 1,000 9,864E-04 0,01975261 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 9,864E-04 0,01959202 ! hemoglobin metabolic process GO:0020027 14 8 1,000 9,864E-04 0,01943402 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 9,864E-04 0,01927855 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 9,864E-04 0,01912555 ! response to UV-B GO:0010224 17 8 1,000 9,864E-04 0,01897495 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 9,864E-04 0,01882671 ! positive regulation of interferon-gamma production GO:0032729 12 8 1,000 9,864E-04 0,01868077 ! regulation of immune response to tumor cell GO:0002837 15 8 1,000 9,864E-04 0,01853707 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 9,864E-04 0,01839556 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 9,864E-04 0,0182562 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 9,864E-04 0,01811894 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 9,864E-04 0,01798372 ! positive regulation of gene-specific transcription GO:0043193 70 33 2,000 1,028E-03 0,01859623 ! acute inflammatory response GO:0002526 118 74 3,000 1,057E-03 0,0189927 ! leukocyte mediated immunity GO:0002443 136 75 3,000 1,112E-03 0,01982333 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 1,122E-03 0,01986438 ! membrane docking GO:0022406 69 35 2,000 1,222E-03 0,02147515 ! placenta development GO:0001890 53 35 2,000 1,222E-03 0,02132176 ! regulation of catabolic process GO:0009894 173 77 3,000 1,226E-03 0,02124541 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,263E-03 0,02173277 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,263E-03 0,02158079 ! artery development GO:0060840 25 9 1,000 1,263E-03 0,02143093 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 20 9 1,000 1,263E-03 0,02128313 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 1,000 1,263E-03 0,02113735 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 1,000 1,263E-03 0,02099356 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 1,000 1,263E-03 0,02085171 ! regulation of Notch signaling pathway GO:0008593 24 9 1,000 1,263E-03 0,02071177 ! postreplication repair GO:0006301 25 9 1,000 1,263E-03 0,02057369 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 2,000 1,327E-03 0,02147049 ! regulation of proteolysis GO:0030162 77 36 2,000 1,327E-03 0,02132924 ! blood coagulation GO:0007596 151 79 3,000 1,349E-03 0,02153582 GO:0050817|coagulation, ! tissue remodeling GO:0048771 78 37 2,000 1,438E-03 0,02280872 ! regulation of peptidase activity GO:0052547 150 82 3,000 1,548E-03 0,0244019 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 2,000 1,554E-03 0,02433846 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 2,000 1,554E-03 0,02418344 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 1,573E-03 0,02431822 ! COPI coating of Golgi vesicle GO:0048205 23 10 1,000 1,573E-03 0,02416527 GO:0048200|Golgi transport vesicle coating, ! pathogenesis GO:0009405 17 10 1,000 1,573E-03 0,02401424 ! positive regulation of survival gene product expression GO:0045885 26 10 1,000 1,573E-03 0,02386508 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,573E-03 0,02371777 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 1,000 1,573E-03 0,02357226 GO:0006600|creatine metabolic process, ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 1,573E-03 0,02342853 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,573E-03 0,02328654 GO:0045685|regulation of glial cell differentiation, ! response to dsRNA GO:0043331 23 10 1,000 1,573E-03 0,02314626 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 1,000 1,573E-03 0,02300766 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,573E-03 0,02287071 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,573E-03 0,02273538 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 1,676E-03 0,02408862 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! hemostasis GO:0007599 165 85 3,000 1,767E-03 0,02524932 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 2,000 1,804E-03 0,0256255 GO:0006956|complement activation, ! thyroid gland development GO:0030878 26 11 1,000 1,915E-03 0,02703766 ! Golgi vesicle budding GO:0048194 26 11 1,000 1,915E-03 0,02688227 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,915E-03 0,02672866 ! melanocyte differentiation GO:0030318 20 11 1,000 1,915E-03 0,02657679 GO:0050931|pigment cell differentiation, ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 1,915E-03 0,02642664 ! positive regulation of T cell mediated immunity GO:0002711 26 11 1,000 1,915E-03 0,02627818 ! neuroblast proliferation GO:0007405 25 11 1,000 1,915E-03 0,02613137 ! thymus development GO:0048538 29 11 1,000 1,915E-03 0,0259862 ! germ cell migration GO:0008354 26 11 1,000 1,915E-03 0,02584263 ! mitochondrion organization GO:0007005 159 87 3,000 1,925E-03 0,02583725 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 1,938E-03 0,02587213 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 2,000 2,078E-03 0,0275888 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 2,078E-03 0,02743967 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 2,000 2,224E-03 0,02920986 ! glucose transport GO:0015758 66 43 2,000 2,224E-03 0,02905366 ! regulation of T cell proliferation GO:0042129 80 43 2,000 2,224E-03 0,02889912 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 2,224E-03 0,02874621 ! gland development GO:0048732 220 91 3,000 2,268E-03 0,02916767 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 1,000 2,288E-03 0,02927118 ! regulation of cell projection assembly GO:0060491 33 12 1,000 2,288E-03 0,02911872 ! hippocampus development GO:0021766 29 12 1,000 2,288E-03 0,02896785 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,288E-03 0,02881853 ! drug transport GO:0015893 16 12 1,000 2,288E-03 0,02867074 ! focal adhesion formation GO:0048041 37 12 1,000 2,288E-03 0,02852446 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 1,000 2,288E-03 0,02837967 GO:0002717|positive regulation of natural killer cell mediated immunity, ! synaptic vesicle exocytosis GO:0016079 22 12 1,000 2,288E-03 0,02823634 ! regulation of hormone metabolic process GO:0032350 28 12 1,000 2,288E-03 0,02809445 ! T cell homeostasis GO:0043029 28 12 1,000 2,288E-03 0,02795397 ! defense response to Gram-positive bacterium GO:0050830 14 12 1,000 2,288E-03 0,0278149 ! embryonic placenta development GO:0001892 21 12 1,000 2,288E-03 0,0276772 ! lamellipodium assembly GO:0030032 24 12 1,000 2,288E-03 0,02754086 ! hexose transport GO:0008645 68 44 2,000 2,376E-03 0,02845542 GO:0015749|monosaccharide transport, ! receptor-mediated endocytosis GO:0006898 98 45 2,000 2,535E-03 0,0302057 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 2,694E-03 0,03194736 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 1,000 2,694E-03 0,03179302 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! gland morphogenesis GO:0022612 31 13 1,000 2,694E-03 0,03164017 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 2,694E-03 0,03148878 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,694E-03 0,03133883 ! regulation of chemokine production GO:0032642 18 13 1,000 2,694E-03 0,03119031 ! organelle fusion GO:0048284 36 13 1,000 2,694E-03 0,03104319 ! pseudouridine synthesis GO:0001522 19 13 1,000 2,694E-03 0,03089744 ! endocrine pancreas development GO:0031018 25 13 1,000 2,694E-03 0,03075306 ! positive regulation of cell growth GO:0030307 24 13 1,000 2,694E-03 0,03061002 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,694E-03 0,03046831 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,7E-03 0,03039187 ! glycolysis GO:0006096 71 46 2,000 2,7E-03 0,03025245 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 2,7E-03 0,03011432 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 2,7E-03 0,02997743 ! positive regulation of cell cycle GO:0045787 96 48 2,000 3,049E-03 0,03370314 ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 1,000 3,13E-03 0,03444885 ! lipid localization GO:0010876 32 14 1,000 3,13E-03 0,03429437 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 1,000 3,13E-03 0,03414127 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 3,13E-03 0,03398953 ! positive regulation of immune response GO:0050778 175 100 3,000 3,192E-03 0,0344997 ! JNK cascade GO:0007254 106 49 2,000 3,233E-03 0,0347986 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 3,233E-03 0,03464597 ! protein homooligomerization GO:0051260 84 49 2,000 3,233E-03 0,03449468 ! immunoglobulin mediated immune response GO:0016064 89 50 2,000 3,425E-03 0,03637635 GO:0019724|B cell mediated immunity, ! positive regulation of cytokine production GO:0001819 94 50 2,000 3,425E-03 0,03621888 ! tRNA modification GO:0006400 24 15 1,000 3,598E-03 0,03788499 ! vesicle coating GO:0006901 38 15 1,000 3,598E-03 0,03772239 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 3,598E-03 0,03756118 ! regulation of vasodilation GO:0042312 27 15 1,000 3,598E-03 0,03740135 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 3,598E-03 0,03724287 ! muscle maintenance GO:0046716 26 15 1,000 3,598E-03 0,03708573 ! cell killing GO:0001906 32 15 1,000 3,598E-03 0,0369299 ! lymphocyte homeostasis GO:0002260 33 15 1,000 3,598E-03 0,03677539 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 3,598E-03 0,03662216 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 1,000 3,598E-03 0,0364702 ! actin filament polymerization GO:0030041 27 15 1,000 3,598E-03 0,03631949 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 2,000 3,623E-03 0,03642147 ! amino acid activation GO:0043038 98 52 2,000 3,828E-03 0,03832388 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 4,04E-03 0,04027987 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 2,000 4,04E-03 0,04011613 ! vesicle organization GO:0016050 127 53 2,000 4,04E-03 0,03995372 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 4,04E-03 0,03979261 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,095E-03 0,04018169 ! positive regulation of cell size GO:0045793 29 16 1,000 4,095E-03 0,04002096 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 4,095E-03 0,03986151 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 4,095E-03 0,03970333 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,095E-03 0,0395464 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 1,000 4,095E-03 0,03939071 ! regulation of angiogenesis GO:0045765 125 54 2,000 4,258E-03 0,04079689 ! membrane fusion GO:0006944 122 54 2,000 4,258E-03 0,04063753 ! regulation of cell shape GO:0008360 142 54 2,000 4,258E-03 0,0404794 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 4,484E-03 0,04246166 ! response to UV GO:0009411 120 55 2,000 4,484E-03 0,04229771 ! positive regulation of cell killing GO:0031343 36 17 1,000 4,623E-03 0,04344033 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 4,623E-03 0,04327389 ! signal complex assembly GO:0007172 47 17 1,000 4,623E-03 0,04310872 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 1,000 4,623E-03 0,04294481 ! activation of MAPKK activity GO:0000186 43 17 1,000 4,623E-03 0,04278214 ! complement activation, alternative pathway GO:0006957 19 17 1,000 4,623E-03 0,0426207 ! membrane budding GO:0006900 42 17 1,000 4,623E-03 0,04246047 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 4,623E-03 0,04230144 ! glucose catabolic process GO:0006007 88 56 2,000 4,717E-03 0,0430016 ! regulation of protein catabolic process GO:0042176 126 56 2,000 4,717E-03 0,04284174 ! regulation of intracellular transport GO:0032386 108 57 2,000 4,958E-03 0,04485677 ! limbic system development GO:0021761 40 18 1,000 5,181E-03 0,0467016 ! patterning of blood vessels GO:0001569 43 18 1,000 5,181E-03 0,0465299 ! heart looping GO:0001947 34 18 1,000 5,181E-03 0,04635946 ! cell-substrate junction assembly GO:0007044 56 18 1,000 5,181E-03 0,04619027 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 1,000 5,181E-03 0,0460223 ! neural crest cell migration GO:0001755 41 18 1,000 5,181E-03 0,04585555 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 5,181E-03 0,04569001 ! establishment of organelle localization GO:0051656 122 59 2,000 5,46E-03 0,04798001 ! pigmentation during development GO:0048066 42 19 1,000 5,767E-03 0,05049919 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 1,000 5,767E-03 0,05031884 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 6,383E-03 0,05549113 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 6,383E-03 0,05529435 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 1,000 6,383E-03 0,05509897 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 6,383E-03 0,05490496 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 6,383E-03 0,05471231 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 40 20 1,000 6,383E-03 0,05452101 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 6,383E-03 0,05433104 ! actin filament bundle formation GO:0051017 47 20 1,000 6,383E-03 0,05414239 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 6,383E-03 0,05395504 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 6,383E-03 0,05376899 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 1,000 6,383E-03 0,05358422 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 6,383E-03 0,05340071 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 6,846E-03 0,05707753 ! regulation of cell killing GO:0031341 46 21 1,000 7,027E-03 0,05838925 ! lipid phosphorylation GO:0046834 43 21 1,000 7,027E-03 0,05819132 ! regulation of vasoconstriction GO:0019229 40 21 1,000 7,027E-03 0,05799473 ! collagen fibril organization GO:0030199 62 21 1,000 7,027E-03 0,05779946 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 7,027E-03 0,0576055 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 7,027E-03 0,05741284 ! actin filament-based movement GO:0030048 47 21 1,000 7,027E-03 0,05722146 ! inactivation of MAPK activity GO:0000188 45 22 1,000 7,699E-03 0,06248731 ! actin polymerization or depolymerization GO:0008154 52 22 1,000 7,699E-03 0,0622804 ! cytolysis GO:0019835 27 22 1,000 7,699E-03 0,06207486 ! positive regulation of adaptive immune response GO:0002821 42 22 1,000 7,699E-03 0,06187066 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 7,699E-03 0,06166781 ! peptidyl-serine modification GO:0018209 50 22 1,000 7,699E-03 0,06146628 ! activation of JUN kinase activity GO:0007257 47 22 1,000 7,699E-03 0,06126606 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 7,699E-03 0,06106715 ! activation of MAPK activity GO:0000187 124 67 2,000 7,768E-03 0,06141624 ! hexose catabolic process GO:0019320 113 68 2,000 8,091E-03 0,06376363 ! positive regulation of T cell activation GO:0050870 124 68 2,000 8,091E-03 0,06355861 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 8,399E-03 0,06576557 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 8,399E-03 0,06555546 ! vesicle targeting GO:0006903 49 23 1,000 8,399E-03 0,06534668 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 8,399E-03 0,06513923 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 8,399E-03 0,0649331 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 8,422E-03 0,06490509 ! activation of immune response GO:0002253 120 70 2,000 8,761E-03 0,06730274 ! protein maturation by peptide bond cleavage GO:0051605 118 70 2,000 8,761E-03 0,06709176 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 9,127E-03 0,06967531 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 9,127E-03 0,06945825 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 1,000 9,127E-03 0,06924254 GO:0002708|positive regulation of lymphocyte mediated immunity, ! membrane depolarization GO:0051899 45 24 1,000 9,127E-03 0,06902817 ! pallium development GO:0021543 56 24 1,000 9,127E-03 0,06881512 ! synaptic vesicle transport GO:0048489 52 24 1,000 9,127E-03 0,06860338 ! platelet activation GO:0030168 41 24 1,000 9,127E-03 0,06839294 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 1,000 9,127E-03 0,06818379 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 9,127E-03 0,06797591 ! carbohydrate transport GO:0008643 114 72 2,000 9,462E-03 0,07025801 ! coenzyme biosynthetic process GO:0009108 119 72 2,000 9,462E-03 0,07004511 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 9,462E-03 0,06983349 ! humoral immune response GO:0006959 115 73 2,000 9,824E-03 0,07229011 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 9,881E-03 0,07249112 ! vasculogenesis GO:0001570 49 25 1,000 9,881E-03 0,07227408 ! receptor metabolic process GO:0043112 53 25 1,000 9,881E-03 0,07205834 ! interaction with host GO:0051701 66 25 1,000 9,881E-03 0,07184388 ! leukocyte homeostasis GO:0001776 50 25 1,000 9,881E-03 0,07163069 ! regulation of caspase activity GO:0043281 136 74 2,000 0,01019455 0,07368424 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 0,01019455 0,07346688 ! organelle localization GO:0051640 155 74 2,000 0,01019455 0,07325081 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 0,01066244 0,07638808 ! molting cycle process GO:0022404 52 26 1,000 0,01066244 0,07616473 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 0,01066244 0,07594267 ! vesicle docking during exocytosis GO:0006904 49 26 1,000 0,01066244 0,07572191 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 0,01066244 0,07550242 ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 0,01066244 0,07528421 ! neural crest cell development GO:0014032 59 26 1,000 0,01066244 0,07506725 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 83 26 1,000 0,01066244 0,07485154 GO:0050768|negative regulation of neurogenesis, ! regulation of blood coagulation GO:0030193 46 26 1,000 0,01066244 0,07463707 ! positive regulation of nuclear division GO:0051785 41 26 1,000 0,01066244 0,07442382 GO:0045840|positive regulation of mitosis, ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 0,01066244 0,07421178 ! cell-matrix adhesion GO:0007160 181 76 2,000 0,01095951 0,07606272 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 0,0113541 0,0785781 ! monosaccharide catabolic process GO:0046365 125 77 2,000 0,0113541 0,07835613 ! positive regulation of cell projection organization GO:0031346 66 27 1,000 0,01147017 0,07893418 ! regulation of interferon-gamma production GO:0032649 43 27 1,000 0,01147017 0,07871245 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 0,01147017 0,07849197 ! mitochondrial membrane organization GO:0007006 60 27 1,000 0,01147017 0,07827272 ! response to toxin GO:0009636 49 27 1,000 0,01147017 0,07805469 ! cellular response to oxidative stress GO:0034599 43 27 1,000 0,01147017 0,07783787 ! regulation of chromosome organization GO:0033044 49 27 1,000 0,01147017 0,07762225 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 0,01175681 0,07934221 ! protein oligomerization GO:0051259 149 79 2,000 0,01216765 0,08188863 ! neuron fate commitment GO:0048663 52 28 1,000 0,01230397 0,08257855 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 0,01230397 0,08235231 ! fat cell differentiation GO:0045444 57 28 1,000 0,01230397 0,0821273 ! positive regulation of innate immune response GO:0045089 49 28 1,000 0,01230397 0,08190352 ! regulation of response to biotic stimulus GO:0002831 52 28 1,000 0,01230397 0,08168096 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 0,01230397 0,0814596 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 0,01230397 0,08123944 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 2,000 0,01258666 0,08288197 ! activation of protein kinase activity GO:0032147 170 80 2,000 0,01258666 0,08265917 ! response to hypoxia GO:0001666 178 81 2,000 0,01301385 0,08523552 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 0,01301385 0,08500761 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01316348 0,0857557 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01316348 0,08552762 ! cell-substrate adhesion GO:0031589 189 82 2,000 0,01344926 0,08715262 ! protein import into nucleus GO:0006606 174 82 2,000 0,01344926 0,08692206 ! response to oxygen levels GO:0070482 183 83 2,000 0,01389289 0,08955234 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 0,01389289 0,08931667 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 2,000 0,01389289 0,08908225 ! acute-phase response GO:0006953 50 30 1,000 0,01404838 0,08984343 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 0,01404838 0,08960885 ! neurotransmitter secretion GO:0007269 55 30 1,000 0,01404838 0,0893755 ! regulation of coagulation GO:0050818 52 30 1,000 0,01404838 0,08914335 ! cell junction assembly GO:0034329 85 31 1,000 0,01495833 0,09467148 ! regulation of innate immune response GO:0045088 57 31 1,000 0,01495833 0,09442685 ! peptide transport GO:0015833 60 31 1,000 0,01495833 0,09418348 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01495833 0,09394136 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01495833 0,09370049 ! response to heat GO:0009408 54 31 1,000 0,01495833 0,09346085 ! positive regulation of immune effector process GO:0002699 78 31 1,000 0,01495833 0,09322242 ! positive regulation of cell activation GO:0050867 161 86 2,000 0,01527336 0,09494355 GO:0002696|positive regulation of leukocyte activation, ! alcohol catabolic process GO:0046164 142 87 2,000 0,01575009 0,09765856 ! regulation of protein transport GO:0051223 165 87 2,000 0,01575009 0,09741132 GO:0070201|regulation of establishment of protein localization, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01589299 0,09804691 ! collagen metabolic process GO:0032963 49 32 1,000 0,01589299 0,09779994 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 0,01589299 0,09755421 ! one-carbon metabolic process GO:0006730 167 88 2,000 0,01623514 0,09940461 ! regulation of DNA binding GO:0051101 167 89 2,000 0,01672851 0,10216938 ! protein localization in nucleus GO:0034504 192 89 2,000 0,01672851 0,10191459 ! cholesterol homeostasis GO:0042632 60 33 1,000 0,01685205 0,10241182 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 0,01685205 0,10215769 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01685205 0,10190483 ! establishment of vesicle localization GO:0051650 67 33 1,000 0,01685205 0,10165321 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,01723022 0,1036784 ! post-embryonic development GO:0009791 76 34 1,000 0,01783517 0,10705483 ! cholesterol transport GO:0030301 62 34 1,000 0,01783517 0,10679244 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01783517 0,10653134 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 0,01878548 0,11193399 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01878548 0,11166165 ! mRNA export from nucleus GO:0006406 53 35 1,000 0,01884203 0,11172595 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,01884203 0,11145543 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 0,01884203 0,11118621 ! telencephalon development GO:0021537 81 35 1,000 0,01884203 0,11091829 ! sterol transport GO:0015918 63 35 1,000 0,01884203 0,11065166 ! vesicle localization GO:0051648 70 35 1,000 0,01884203 0,11038631 ! cofactor biosynthetic process GO:0051188 161 95 2,000 0,01986418 0,11609615 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01987233 0,11586657 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01987233 0,1155907 ! embryonic organ development GO:0048568 67 36 1,000 0,01987233 0,11531614 ! regulation of T cell activation GO:0050863 175 96 2,000 0,0204161 0,11819084 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,02092573 0,12085474 ! sister chromatid segregation GO:0000819 65 37 1,000 0,02092573 0,1205697 ! cell junction organization GO:0034330 96 37 1,000 0,02092573 0,12028601 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,02092573 0,12000365 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,02092573 0,11972261 ! regulation of protein localization GO:0032880 188 97 2,000 0,02097641 0,11973217 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 0,02154511 0,12269161 ! forebrain development GO:0030900 210 98 2,000 0,02154511 0,12240628 ! meiosis I GO:0007127 74 38 1,000 0,02200193 0,12471162 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,02200193 0,12442293 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,02200193 0,12413558 GO:0006639|acylglycerol metabolic process, ! glycogen metabolic process GO:0005977 63 38 1,000 0,02200193 0,12384956 ! mRNA transport GO:0051028 185 100 2,000 0,02270769 0,12752845 ! negative regulation of binding GO:0051100 71 39 1,000 0,02310061 0,12943761 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,02310061 0,12914141 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 0,02310061 0,12884657 ! nucleotide catabolic process GO:0009166 70 39 1,000 0,02310061 0,12855307 ! glucan metabolic process GO:0044042 64 39 1,000 0,02310061 0,1282609 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,02422148 0,1341793 ! lipid homeostasis GO:0055088 75 40 1,000 0,02422148 0,13387572 ! glycerol ether metabolic process GO:0006662 57 40 1,000 0,02422148 0,13357352 ! Rho protein signal transduction GO:0007266 88 40 1,000 0,02422148 0,13327268 ! RNA export from nucleus GO:0006405 61 41 1,000 0,02536422 0,13924671 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,02536422 0,1389345 ! mesenchymal cell development GO:0014031 94 41 1,000 0,02536422 0,13862368 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 95 41 1,000 0,02536422 0,13831426 ! RNA modification GO:0009451 64 41 1,000 0,02536422 0,13800621 ! organic ether metabolic process GO:0018904 59 42 1,000 0,02652853 0,14402046 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 0,02652853 0,14370113 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 0,02652853 0,14338321 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,02771413 0,1494605 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 0,0289207 0,15562392 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,0289207 0,15528189 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02974487 0,15935686 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02974487 0,15900816 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02974487 0,15866098 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02974487 0,15831531 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02974487 0,15797115 ! neuron fate determination GO:0048664 7 5 0,000 0,02974487 0,15762848 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02974487 0,15728729 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02974487 0,15694758 ! polyol transport GO:0015791 12 5 0,000 0,02974487 0,15660933 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02974487 0,15627253 ! response to superoxide GO:0000303 10 5 0,000 0,02974487 0,15593718 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02974487 0,15560327 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02974487 0,15527078 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02974487 0,15493972 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02974487 0,15461006 ! female meiosis GO:0007143 10 5 0,000 0,02974487 0,1542818 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02974487 0,15395493 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02974487 0,15362944 ! hypothalamus development GO:0021854 9 5 0,000 0,02974487 0,15330533 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02974487 0,15298258 ! cobalt ion transport GO:0006824 11 5 0,000 0,02974487 0,15266119 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02974487 0,15234115 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02974487 0,15202244 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02974487 0,15170507 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02974487 0,15138902 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02974487 0,15107428 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02974487 0,15076084 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02974487 0,15044871 GO:0006451|translational readthrough, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02974487 0,15013787 ! transposition GO:0032196 9 5 0,000 0,02974487 0,1498283 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02974487 0,14952001 ! negative chemotaxis GO:0050919 16 5 0,000 0,02974487 0,14921299 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02974487 0,14890723 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02974487 0,14860271 ! behavioral response to pain GO:0048266 10 5 0,000 0,02974487 0,14829944 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02974487 0,14799741 ! Notch receptor processing GO:0007220 11 5 0,000 0,02974487 0,1476966 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02974487 0,14739701 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02974487 0,14709864 ! micturition GO:0060073 9 5 0,000 0,02974487 0,14680147 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02974487 0,1465055 ! copulation GO:0007620 9 5 0,000 0,02974487 0,14621072 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02974487 0,14591712 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02974487 0,1456247 ! bioluminescence GO:0008218 9 5 0,000 0,02974487 0,14533345 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02974487 0,14504337 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02974487 0,14475444 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02974487 0,14446665 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02974487 0,14418001 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02974487 0,14389451 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02974487 0,14361013 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02974487 0,14332688 ! grooming behavior GO:0007625 6 5 0,000 0,02974487 0,14304474 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02974487 0,14276371 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02974487 0,14248378 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02974487 0,14220495 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02974487 0,1419272 ! response to protozoan GO:0001562 13 5 0,000 0,02974487 0,14165054 ! lymph vessel development GO:0001945 10 5 0,000 0,02974487 0,14137496 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02974487 0,14110044 ! endochondral ossification GO:0001958 17 5 0,000 0,02974487 0,14082699 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02974487 0,1405546 ! single strand break repair GO:0000012 8 5 0,000 0,02974487 0,14028326 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02974487 0,14001296 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02974487 0,13974371 ! cytokine secretion GO:0050663 15 5 0,000 0,02974487 0,13947548 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02974487 0,13920829 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02974487 0,13894212 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02974487 0,13867696 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02974487 0,13841281 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02974487 0,13814967 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02974487 0,13788753 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02974487 0,13762638 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02974487 0,13736621 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02974487 0,13710703 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02974487 0,13684883 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02974487 0,13659159 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02974487 0,13633532 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02974487 0,13608001 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02974487 0,13582566 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02974487 0,13557225 ! microvillus organization GO:0032528 8 5 0,000 0,02974487 0,13531979 GO:0030033|microvillus assembly, ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02974487 0,13506827 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02974487 0,13481768 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02974487 0,13456801 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02974487 0,13431927 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02974487 0,13407145 ! polyol catabolic process GO:0046174 9 5 0,000 0,02974487 0,13382454 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02974487 0,13357854 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02974487 0,13333344 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02974487 0,13308924 ! muscle cell migration GO:0014812 8 5 0,000 0,02974487 0,13284594 ! mitochondrial fission GO:0000266 8 5 0,000 0,02974487 0,13260352 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02974487 0,13236198 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02974487 0,13212132 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02974487 0,13188154 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02974487 0,13164262 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02974487 0,13140457 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02974487 0,13116738 ! monocyte activation GO:0042117 10 5 0,000 0,02974487 0,13093104 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02974487 0,13069555 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02974487 0,13046091 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02974487 0,13022711 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02974487 0,12999415 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02974487 0,12976201 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02974487 0,12953071 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02974487 0,12930023 ! forebrain neuron development GO:0021884 13 5 0,000 0,02974487 0,12907056 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02974487 0,12884171 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02974487 0,12861368 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02974487 0,12838644 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02974487 0,12816001 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02974487 0,12793438 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02974487 0,12770954 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02974487 0,12748549 ! lipid glycosylation GO:0030259 7 5 0,000 0,02974487 0,12726222 ! nucleobase transport GO:0015851 6 5 0,000 0,02974487 0,12703973 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02974487 0,12681802 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02974487 0,12659709 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02974487 0,12637692 ! basic amino acid transport GO:0015802 12 5 0,000 0,02974487 0,12615751 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02974487 0,12593887 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02974487 0,12572098 ! actin nucleation GO:0045010 11 5 0,000 0,02974487 0,12550385 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02974487 0,12528746 ! depurination GO:0045007 5 5 0,000 0,02974487 0,12507182 ! depyrimidination GO:0045008 10 5 0,000 0,02974487 0,12485692 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02974487 0,12464276 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02974487 0,12442933 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02974487 0,12421663 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02974487 0,12400465 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02974487 0,1237934 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02974487 0,12358287 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02974487 0,12337305 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02974487 0,12316394 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02974487 0,12295555 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02974487 0,12274785 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02974487 0,12254086 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02974487 0,12233456 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02974487 0,12212895 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02974487 0,12192404 ! response to arsenic GO:0046685 11 5 0,000 0,02974487 0,12171981 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02974487 0,12151627 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02974487 0,1213134 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02974487 0,12111121 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02974487 0,1209097 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02974487 0,12070885 ! response to mercury ion GO:0046689 8 5 0,000 0,02974487 0,12050867 ! response to cadmium ion GO:0046686 7 5 0,000 0,02974487 0,12030915 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02974487 0,12011029 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02974487 0,11991209 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02974487 0,11971454 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02974487 0,11951764 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02974487 0,11932139 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02974487 0,11912578 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02974487 0,11893081 ! decidualization GO:0046697 11 5 0,000 0,02974487 0,11873648 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02974487 0,11854279 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02974487 0,11834972 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02974487 0,11815728 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02974487 0,11796547 ! embryonic cleavage GO:0040016 6 5 0,000 0,02974487 0,11777427 ! peroxisome fission GO:0016559 5 5 0,000 0,02974487 0,1175837 ! histone demethylation GO:0016577 13 5 0,000 0,02974487 0,11739374 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02974487 0,1172044 ! mitotic recombination GO:0006312 9 5 0,000 0,02974487 0,11701566 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02974487 0,11682754 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02974487 0,11664001 ! metaphase plate congression GO:0051310 7 5 0,000 0,02974487 0,11645309 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02974487 0,11626676 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02974487 0,11608103 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02974487 0,1158959 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02974487 0,11571135 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02974487 0,11552739 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02974487 0,11534401 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02974487 0,11516122 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02974487 0,114979 ! B cell homeostasis GO:0001782 13 5 0,000 0,02974487 0,11479736 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02974487 0,11461629 ! metaphase GO:0051323 11 5 0,000 0,02974487 0,11443579 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02974487 0,11425586 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02974487 0,11407649 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02974487 0,11389769 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02974487 0,11371945 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02974487 0,11354176 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02974487 0,11336463 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02974487 0,11318805 ! response to redox state GO:0051775 6 5 0,000 0,02974487 0,11301202 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02974487 0,11283653 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02974487 0,11266159 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02974487 0,11248719 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02974487 0,11231333 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02974487 0,11214001 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02974487 0,11196722 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02974487 0,11179496 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02974487 0,11162324 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02974487 0,11145204 ! striatum development GO:0021756 14 5 0,000 0,02974487 0,11128136 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02974487 0,1111112 ! glial cell migration GO:0008347 10 5 0,000 0,02974487 0,11094157 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02974487 0,11077245 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02974487 0,11060385 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02974487 0,11043576 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02974487 0,11026817 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02974487 0,1101011 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02974487 0,10993453 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02974487 0,10976847 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02974487 0,10960291 ! neuroprotection GO:0043526 8 5 0,000 0,02974487 0,10943784 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02974487 0,10927327 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02974487 0,1091092 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02974487 0,10894562 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02974487 0,10878253 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02974487 0,10861992 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02974487 0,1084578 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02974487 0,10829617 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02974487 0,10813501 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02974487 0,10797433 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02974487 0,10781414 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02974487 0,10765441 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02974487 0,10749516 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02974487 0,10733638 ! spindle assembly GO:0051225 6 5 0,000 0,02974487 0,10717806 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02974487 0,10702022 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02974487 0,10686283 ! protein palmitoylation GO:0018345 12 5 0,000 0,02974487 0,10670591 ! drug metabolic process GO:0017144 7 5 0,000 0,02974487 0,10654945 ! stem cell division GO:0017145 11 5 0,000 0,02974487 0,10639345 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02974487 0,10623791 ! organ regeneration GO:0031100 7 5 0,000 0,02974487 0,10608281 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02974487 0,10592817 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02974487 0,10577398 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,03014795 0,10705153 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,03014795 0,10689615 ! developmental growth GO:0048589 88 45 1,000 0,03014795 0,10674123 ! maintenance of location in cell GO:0051651 101 45 1,000 0,03014795 0,10658676 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,03139561 0,11083738 ! leukocyte migration GO:0050900 75 46 1,000 0,03139561 0,11067744 ! pigmentation GO:0043473 103 46 1,000 0,03139561 0,11051797 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,03139561 0,11035895 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,03266337 0,11465031 ! positive regulation of defense response GO:0031349 88 48 1,000 0,03395096 0,11899884 ! mitochondrial transport GO:0006839 94 48 1,000 0,03395096 0,11882835 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,03395096 0,11865835 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,03395096 0,11848884 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,03395096 0,11831981 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03558732 0,12384589 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03558732 0,12366972 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03558732 0,12349406 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03558732 0,12331889 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03558732 0,12314422 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03558732 0,12297004 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03558732 0,12279635 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03558732 0,12262315 ! response to oxygen radical GO:0000305 11 6 0,000 0,03558732 0,12245045 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03558732 0,12227822 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03558732 0,12210648 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03558732 0,12193523 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03558732 0,12176445 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03558732 0,12159415 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03558732 0,12142432 ! forebrain regionalization GO:0021871 9 6 0,000 0,03558732 0,12125497 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03558732 0,1210861 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03558732 0,12091769 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03558732 0,12074975 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03558732 0,12058227 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03558732 0,12041526 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03558732 0,12024871 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03558732 0,12008262 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03558732 0,11991699 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03558732 0,11975181 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03558732 0,11958709 ! malate metabolic process GO:0006108 13 6 0,000 0,03558732 0,11942282 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03558732 0,11925901 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03558732 0,11909564 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03558732 0,11893272 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03558732 0,11877024 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03558732 0,11860821 ! opsonization GO:0008228 8 6 0,000 0,03558732 0,11844662 ! mating behavior GO:0007617 7 6 0,000 0,03558732 0,11828546 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03558732 0,11812475 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03558732 0,11796447 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03558732 0,11780463 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03558732 0,11764522 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03558732 0,11748624 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03558732 0,11732769 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03558732 0,11716956 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03558732 0,11701187 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03558732 0,11685459 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03558732 0,11669774 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03558732 0,11654131 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03558732 0,1163853 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03558732 0,1162297 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03558732 0,11607452 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03558732 0,11591976 ! thymic T cell selection GO:0045061 16 6 0,000 0,03558732 0,1157654 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03558732 0,11561146 ! protein lipoylation GO:0009249 10 6 0,000 0,03558732 0,11545792 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03558732 0,1153048 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03558732 0,11515207 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03558732 0,11499976 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03558732 0,11484784 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03558732 0,11469633 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03558732 0,11454521 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03558732 0,1143945 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03558732 0,11424417 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03558732 0,11409425 ! hyperosmotic response GO:0006972 10 6 0,000 0,03558732 0,11394471 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03558732 0,11379557 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03558732 0,11364682 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03558732 0,11349845 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03558732 0,11335048 ! urea metabolic process GO:0019627 7 6 0,000 0,03558732 0,11320289 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03558732 0,11305568 ! neutrophil activation GO:0042119 7 6 0,000 0,03558732 0,11290885 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03558732 0,11276241 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03558732 0,11261634 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03558732 0,11247066 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03558732 0,11232534 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03558732 0,11218041 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03558732 0,11203585 ! neuron apoptosis GO:0051402 15 6 0,000 0,03558732 0,11189166 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03558732 0,11174784 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03558732 0,11160439 ! carnitine transport GO:0015879 10 6 0,000 0,03558732 0,1114613 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03558732 0,11131859 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03558732 0,11117624 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03558732 0,11103425 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03558732 0,11089262 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03558732 0,11075136 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03558732 0,11061045 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03558732 0,11046991 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03558732 0,11032972 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03558732 0,11018988 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03558732 0,1100504 ! neural nucleus development GO:0048857 19 6 0,000 0,03558732 0,10991127 ! response to UV-C GO:0010225 14 6 0,000 0,03558732 0,1097725 ! astrocyte development GO:0014002 16 6 0,000 0,03558732 0,10963407 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03558732 0,10949599 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03558732 0,10935826 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03558732 0,10922088 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03558732 0,10908384 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03558732 0,10894714 ! response to copper ion GO:0046688 10 6 0,000 0,03558732 0,10881078 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03558732 0,10867477 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03558732 0,1085391 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03558732 0,10840376 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03558732 0,10826876 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03558732 0,1081341 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03558732 0,10799977 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03558732 0,10786578 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03558732 0,10773211 ! Schwann cell development GO:0014044 15 6 0,000 0,03558732 0,10759878 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03558732 0,10746578 ! response to pheromone GO:0019236 6 6 0,000 0,03558732 0,10733311 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03558732 0,10720076 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03558732 0,10706874 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03558732 0,10693704 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03558732 0,10680567 ! subpallium development GO:0021544 15 6 0,000 0,03558732 0,10667462 ! neural tube patterning GO:0021532 8 6 0,000 0,03558732 0,10654389 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03558732 0,10641348 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03558732 0,10628339 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03558732 0,10615362 ! G2 phase GO:0051319 16 6 0,000 0,03558732 0,10602417 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03558732 0,10589503 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03558732 0,1057662 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03558732 0,10563769 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03558732 0,10550949 ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03558732 0,1053816 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03558732 0,10525402 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03558732 0,10512674 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03558732 0,10499978 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03558732 0,10487312 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03558732 0,10474677 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03558732 0,10462072 ! protein deubiquitination GO:0016579 16 6 0,000 0,03558732 0,10449497 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03558732 0,10436953 ! protein destabilization GO:0031648 9 6 0,000 0,03558732 0,10424438 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03558732 0,10411954 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03558732 0,103995 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03558732 0,10387075 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03558732 0,1037468 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03558732 0,10362314 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03558732 0,10349978 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03558732 0,10337671 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03558732 0,10325394 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03558732 0,10313145 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03558732 0,10300926 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03558732 0,10288736 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03558732 0,10276574 ! neural plate development GO:0001840 9 6 0,000 0,03558732 0,10264441 ! catecholamine transport GO:0051937 9 6 0,000 0,03558732 0,10252337 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03558732 0,10240261 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03558732 0,10228214 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03558732 0,10216195 ! maternal placenta development GO:0001893 12 6 0,000 0,03558732 0,10204204 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03558732 0,10192241 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03558732 0,10180306 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03558732 0,101684 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03558732 0,10156521 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03558732 0,10144669 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03558732 0,10132846 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03558732 0,1012105 GO:0055081|anion homeostasis, ! activation of caspase activity GO:0006919 95 50 1,000 0,03658448 0,10392544 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,03792985 0,1076221 ! response to temperature stimulus GO:0009266 84 51 1,000 0,03792985 0,10749725 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,03929394 0,11123418 ! excretion GO:0007588 87 52 1,000 0,03929394 0,11110543 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,03929394 0,11097699 ! cartilage development GO:0051216 99 53 1,000 0,04067647 0,11474897 ! tRNA transcription GO:0009304 17 7 0,000 0,04139474 0,11664055 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04139474 0,11650617 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04139474 0,1163721 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04139474 0,11623834 ! regulation of helicase activity GO:0051095 16 7 0,000 0,04139474 0,11610489 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04139474 0,11597174 ! sleep GO:0030431 16 7 0,000 0,04139474 0,1158389 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04139474 0,11570636 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04139474 0,11557412 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04139474 0,11544219 ! prostate gland development GO:0030850 14 7 0,000 0,04139474 0,11531056 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04139474 0,11517922 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04139474 0,11504819 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04139474 0,11491745 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04139474 0,11478701 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04139474 0,11465687 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04139474 0,11452702 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04139474 0,11439746 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04139474 0,1142682 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04139474 0,11413923 ! glycolipid transport GO:0046836 11 7 0,000 0,04139474 0,11401055 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04139474 0,11388216 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04139474 0,11375406 ! neuron adhesion GO:0007158 14 7 0,000 0,04139474 0,11362625 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,04139474 0,11349872 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04139474 0,11337148 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04139474 0,11324452 ! mRNA stabilization GO:0048255 18 7 0,000 0,04139474 0,11311785 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,04139474 0,11299146 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,04139474 0,11286536 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,04139474 0,11273953 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04139474 0,11261399 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04139474 0,11248872 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04139474 0,11236373 ! lipoprotein transport GO:0042953 14 7 0,000 0,04139474 0,11223902 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04139474 0,11211459 ! rhythmic behavior GO:0007622 17 7 0,000 0,04139474 0,11199043 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04139474 0,11186655 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,04139474 0,11174294 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04139474 0,1116196 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04139474 0,11149654 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04139474 0,11137374 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04139474 0,11125122 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04139474 0,11112897 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04139474 0,11100698 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04139474 0,11088526 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04139474 0,11076381 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04139474 0,11064262 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04139474 0,1105217 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04139474 0,11040105 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04139474 0,11028065 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04139474 0,11016052 ! spinal cord patterning GO:0021511 14 7 0,000 0,04139474 0,11004065 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04139474 0,10992104 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04139474 0,10980169 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04139474 0,1096826 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04139474 0,10956377 ! adrenal gland development GO:0030325 17 7 0,000 0,04139474 0,10944519 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04139474 0,10932687 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04139474 0,10920881 ! ovulation GO:0030728 10 7 0,000 0,04139474 0,109091 ! adenohypophysis development GO:0021984 11 7 0,000 0,04139474 0,10897345 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04139474 0,10885615 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04139474 0,1087391 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04139474 0,1086223 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04139474 0,10850575 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04139474 0,10838945 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04139474 0,1082734 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04139474 0,1081576 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04139474 0,10804205 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04139474 0,10792674 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04139474 0,10781168 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04139474 0,10769687 ! galactose metabolic process GO:0006012 13 7 0,000 0,04139474 0,1075823 ! response to dietary excess GO:0002021 8 7 0,000 0,04139474 0,10746797 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04139474 0,10735388 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04139474 0,10724004 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04139474 0,10712644 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,04139474 0,10701308 ! organ growth GO:0035265 15 7 0,000 0,04139474 0,10689996 ! nucleoside transport GO:0015858 11 7 0,000 0,04139474 0,10678707 ! nucleoside salvage GO:0043174 11 7 0,000 0,04139474 0,10667443 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04139474 0,10656202 ! male sex determination GO:0030238 15 7 0,000 0,04139474 0,10644985 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04139474 0,10633792 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04139474 0,10622622 ! parturition GO:0007567 16 7 0,000 0,04139474 0,10611475 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,04139474 0,10600352 ! rRNA modification GO:0000154 14 7 0,000 0,04139474 0,10589252 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04139474 0,10578176 ! spindle checkpoint GO:0031577 16 7 0,000 0,04139474 0,10567122 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04139474 0,10556092 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04139474 0,10545084 ! monocyte differentiation GO:0030224 16 7 0,000 0,04139474 0,105341 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04139474 0,10523138 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04139474 0,10512199 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,04139474 0,10501283 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04139474 0,1049039 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,04139474 0,10479519 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04139474 0,10468671 ! fibrinolysis GO:0042730 11 7 0,000 0,04139474 0,10457845 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,04139474 0,10447041 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04139474 0,1043626 ! eating behavior GO:0042755 8 7 0,000 0,04139474 0,10425501 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04139474 0,10414764 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04139474 0,10404049 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04139474 0,10393357 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04139474 0,10382686 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04139474 0,10372037 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04139474 0,1036141 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04139474 0,10350804 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,04139474 0,10340221 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04139474 0,10329659 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04139474 0,10319118 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04139474 0,10308599 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04139474 0,10298102 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04139474 0,10287626 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04139474 0,10277171 ! histone ubiquitination GO:0016574 9 7 0,000 0,04139474 0,10266737 ! regulation of meiosis GO:0040020 12 7 0,000 0,04139474 0,10256324 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04139474 0,10245933 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04139474 0,10235563 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04139474 0,10225213 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04139474 0,10214885 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04139474 0,10204577 ! transcription termination GO:0006353 14 7 0,000 0,04139474 0,1019429 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04139474 0,10184024 ! anaphase GO:0051322 18 7 0,000 0,04139474 0,10173779 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04139474 0,10163554 ! axonal fasciculation GO:0007413 19 7 0,000 0,04139474 0,10153349 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04139474 0,10143165 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04139474 0,10133002 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,04139474 0,10122859 ! diuresis GO:0030146 12 7 0,000 0,04139474 0,10112736 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04139474 0,10102633 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04139474 0,10092551 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04139474 0,10082488 ! antibiotic transport GO:0042891 9 7 0,000 0,04139474 0,10072446 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04139474 0,10062424 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04139474 0,10052421 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04139474 0,10042439 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04139474 0,10032476 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04139474 0,10022533 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04139474 0,1001261 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04139474 0,10002706 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04139474 0,09992822 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04139474 0,09982957 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04139474 0,09973112 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04139474 0,09963287 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04139474 0,0995348 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04139474 0,09943693 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04139474 0,09933925 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04139474 0,09924177 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04139474 0,09914447 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04139474 0,09904736 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04139474 0,09895045 ! muscle adaptation GO:0043500 13 7 0,000 0,04139474 0,09885372 ! retina homeostasis GO:0001895 12 7 0,000 0,04139474 0,09875719 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04139474 0,09866084 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04139474 0,09856468 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04139474 0,0984687 ! regulation of translational initiation GO:0006446 87 54 1,000 0,04207716 0,09999465 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,04207716 0,09989748 ! regulation of muscle contraction GO:0006937 94 54 1,000 0,04207716 0,09980049 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,04207716 0,09970369 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,04638561 0,10980626 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,04638561 0,10969996 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 1,000 0,04638561 0,10959386 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04716736 0,1113332 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04716736 0,11122574 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04716736 0,11111848 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04716736 0,11101143 ! male meiosis GO:0007140 9 8 0,000 0,04716736 0,11090459 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04716736 0,11079795 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04716736 0,11069151 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04716736 0,11058528 ! meiotic prophase I GO:0007128 14 8 0,000 0,04716736 0,11047926 ! response to zinc ion GO:0010043 12 8 0,000 0,04716736 0,11037343 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04716736 0,11026781 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04716736 0,11016239 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04716736 0,11005718 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04716736 0,10995216 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04716736 0,10984734 ! signal peptide processing GO:0006465 12 8 0,000 0,04716736 0,10974273 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04716736 0,10963831 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04716736 0,10953409 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04716736 0,10943007 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04716736 0,10932625 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04716736 0,10922262 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04716736 0,10911919 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04716736 0,10901596 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04716736 0,10891292 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04716736 0,10881007 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04716736 0,10870742 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04716736 0,10860496 ! reflex GO:0060004 17 8 0,000 0,04716736 0,1085027 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04716736 0,10840063 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04716736 0,10829874 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04716736 0,10819706 ! pigment granule organization GO:0048753 17 8 0,000 0,04716736 0,10809556 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04716736 0,10799425 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04716736 0,10789313 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04716736 0,1077922 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04716736 0,10769146 ! histidine catabolic process GO:0006548 10 8 0,000 0,04716736 0,10759091 GO:0009077|histidine family amino acid catabolic process, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04716736 0,10749055 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04716736 0,10739037 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,04716736 0,10729038 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04716736 0,10719057 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04716736 0,10709095 ! melanin metabolic process GO:0006582 17 8 0,000 0,04716736 0,10699152 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04716736 0,10689227 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04716736 0,1067932 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04716736 0,10669432 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04716736 0,10659562 ! macrophage activation GO:0042116 13 8 0,000 0,04716736 0,1064971 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04716736 0,10639877 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04716736 0,10630061 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04716736 0,10620264 ! purine salvage GO:0043101 12 8 0,000 0,04716736 0,10610485 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04716736 0,10600724 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04716736 0,1059098 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04716736 0,10581255 ! osteoblast development GO:0002076 17 8 0,000 0,04716736 0,10571547 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04716736 0,10561857 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04716736 0,10552185 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04716736 0,10542531 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04716736 0,10532894 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04716736 0,10523275 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04716736 0,10513674 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04716736 0,1050409 ! intermediate filament organization GO:0045109 12 8 0,000 0,04716736 0,10494523 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04716736 0,10484974 ! cellular extravasation GO:0045123 13 8 0,000 0,04716736 0,10475442 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04716736 0,10465928 ! response to antibiotic GO:0046677 11 8 0,000 0,04716736 0,10456431 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04716736 0,10446951 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04716736 0,10437488 ! DNA topological change GO:0006265 12 8 0,000 0,04716736 0,10428042 ! response to tropane GO:0014073 15 8 0,000 0,04716736 0,10418613 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,04716736 0,10409202 ! melanosome transport GO:0032402 13 8 0,000 0,04716736 0,10399807 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04716736 0,1039043 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04716736 0,10381069 ! mast cell activation GO:0045576 14 8 0,000 0,04716736 0,10371725 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04716736 0,10362398 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04716736 0,10353088 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04716736 0,10343794 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04716736 0,10334517 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04716736 0,10325257 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04716736 0,10316013 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04716736 0,10306786 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04716736 0,10297575 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04716736 0,10288381 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04716736 0,10279203 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04716736 0,10270041 ! response to tumor cell GO:0002347 16 8 0,000 0,04716736 0,10260896 ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04716736 0,10251767 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04716736 0,10242655 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04716736 0,10233558 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04716736 0,10224478 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04716736 0,10215414 ! hormone catabolic process GO:0042447 17 8 0,000 0,04716736 0,10206365 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04716736 0,10197333 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04716736 0,10188317 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04716736 0,10179317 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04716736 0,10170332 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04716736 0,10161364 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04716736 0,10152411 ! adult feeding behavior GO:0008343 10 8 0,000 0,04716736 0,10143474 ! ATP catabolic process GO:0006200 11 8 0,000 0,04716736 0,10134553 ! blastocyst growth GO:0001832 19 8 0,000 0,04716736 0,10125647 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04716736 0,10116757 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04716736 0,10107883 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04716736 0,10099024 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04716736 0,10090181 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04716736 0,10081353 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04716736 0,10072541 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04716736 0,10063744 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04716736 0,10054962 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04716736 0,10046196 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04716736 0,10037445 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04716736 0,10028709 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04716736 0,10019988 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04716736 0,10011283 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04716736 0,10002592 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04716736 0,09993917 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04716736 0,09985257 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04716736 0,09976612 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,04785635 0,10113587 ! maintenance of location GO:0051235 124 58 1,000 0,04785635 0,10104845 ! nuclear export GO:0051168 110 59 1,000 0,04934394 0,10409953 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,05084815 0,10718035 ! lipid modification GO:0030258 112 60 1,000 0,05084815 0,10708795 ! kidney development GO:0001822 133 60 1,000 0,05084815 0,10699572 ! camera-type eye development GO:0043010 126 61 1,000 0,05236871 0,11010048 ! axon extension GO:0048675 16 9 0,000 0,05290538 0,11113314 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05290538 0,11103766 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05290538 0,11094235 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05290538 0,1108472 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05290538 0,11075222 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05290538 0,1106574 ! reproductive behavior GO:0019098 22 9 0,000 0,05290538 0,11056274 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05290538 0,11046824 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05290538 0,1103739 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05290538 0,11027973 ! UTP metabolic process GO:0046051 10 9 0,000 0,05290538 0,11018571 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05290538 0,11009186 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,05290538 0,10999816 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05290538 0,10990463 ! regulation of histone modification GO:0031056 14 9 0,000 0,05290538 0,10981125 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05290538 0,10971803 ! equilibrioception GO:0050957 20 9 0,000 0,05290538 0,10962497 ! chemosensory behavior GO:0007635 21 9 0,000 0,05290538 0,10953207 ! microtubule bundle formation GO:0001578 22 9 0,000 0,05290538 0,10943932 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05290538 0,10934674 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05290538 0,1092543 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05290538 0,10916203 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05290538 0,10906991 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05290538 0,10897794 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05290538 0,10888613 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05290538 0,10879448 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05290538 0,10870298 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05290538 0,10861163 ! protein targeting to ER GO:0045047 25 9 0,000 0,05290538 0,10852044 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05290538 0,1084294 ! T cell selection GO:0045058 27 9 0,000 0,05290538 0,10833851 ! glycine catabolic process GO:0006546 15 9 0,000 0,05290538 0,10824777 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05290538 0,10815719 ! endosome organization GO:0007032 20 9 0,000 0,05290538 0,10806676 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05290538 0,10797648 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05290538 0,10788634 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05290538 0,10779636 ! mannose metabolic process GO:0006013 13 9 0,000 0,05290538 0,10770653 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05290538 0,10761685 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05290538 0,10752732 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05290538 0,10743794 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05290538 0,10734871 ! receptor clustering GO:0043113 20 9 0,000 0,05290538 0,10725962 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05290538 0,10717068 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05290538 0,10708189 ! retinol metabolic process GO:0042572 20 9 0,000 0,05290538 0,10699325 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05290538 0,10690475 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05290538 0,1068164 GO:0007351|tripartite regional subdivision, ! macrophage differentiation GO:0030225 15 9 0,000 0,05290538 0,10672819 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05290538 0,10664013 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,05290538 0,10655222 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05290538 0,10646445 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05290538 0,10637682 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05290538 0,10628934 ! response to amine stimulus GO:0014075 13 9 0,000 0,05290538 0,10620201 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05290538 0,10611481 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05290538 0,10602776 ! erythrocyte development GO:0048821 17 9 0,000 0,05290538 0,10594085 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05290538 0,10585409 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05290538 0,10576746 ! renal water homeostasis GO:0003091 15 9 0,000 0,05290538 0,10568098 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05290538 0,10559464 ! icosanoid secretion GO:0032309 15 9 0,000 0,05290538 0,10550844 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05290538 0,10542238 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05290538 0,10533646 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05290538 0,10525068 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05290538 0,10516505 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05290538 0,10507955 ! sterol catabolic process GO:0016127 14 9 0,000 0,05290538 0,10499418 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05290538 0,10490896 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05290538 0,10482388 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05290538 0,10473893 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05290538 0,10465412 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05290538 0,10456945 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05290538 0,10448492 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,05290538 0,10440052 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05290538 0,10431626 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05290538 0,10423213 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05290538 0,10414814 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05290538 0,10406428 ! purine base metabolic process GO:0006144 25 9 0,000 0,05290538 0,10398056 ! pigment granule transport GO:0051904 17 9 0,000 0,05290538 0,10389698 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,05290538 0,10381353 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05290538 0,10373021 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05290538 0,10364703 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05290538 0,10356398 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05290538 0,10348106 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05290538 0,10339827 ! mitochondrion localization GO:0051646 18 9 0,000 0,05290538 0,10331562 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,05390537 0,10518437 ! tRNA processing GO:0008033 102 62 1,000 0,05390537 0,10510042 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,05390537 0,10501661 ! regulation of mitosis GO:0007088 112 63 1,000 0,0554579 0,1079551 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,0554579 0,10786914 ! regulation of developmental growth GO:0048638 16 10 0,000 0,058609 0,11390755 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,058609 0,11381701 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,058609 0,1137266 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,058609 0,11363634 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,058609 0,11354623 ! associative learning GO:0008306 21 10 0,000 0,058609 0,11345625 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,058609 0,11336642 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,058609 0,11327673 ! phosphate transport GO:0006817 24 10 0,000 0,058609 0,11318719 ! cell volume homeostasis GO:0006884 17 10 0,000 0,058609 0,11309778 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,058609 0,11300852 ! CTP metabolic process GO:0046036 11 10 0,000 0,058609 0,11291939 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,058609 0,11283041 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,058609 0,11274157 ! GTP metabolic process GO:0046039 11 10 0,000 0,058609 0,11265287 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,058609 0,1125643 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,058609 0,11247588 ! social behavior GO:0035176 29 10 0,000 0,058609 0,11238759 ! smoothened signaling pathway GO:0007224 18 10 0,000 0,058609 0,11229944 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,058609 0,11221144 ! androgen metabolic process GO:0008209 17 10 0,000 0,058609 0,11212356 ! phospholipid efflux GO:0033700 19 10 0,000 0,058609 0,11203583 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,058609 0,11194823 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,058609 0,11186078 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,058609 0,11177345 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,058609 0,11168627 ! lung alveolus development GO:0048286 26 10 0,000 0,058609 0,11159921 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,058609 0,1115123 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,058609 0,11142552 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,058609 0,11133887 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,058609 0,11125236 ! endoderm development GO:0007492 18 10 0,000 0,058609 0,11116599 ! arginine catabolic process GO:0006527 17 10 0,000 0,058609 0,11107975 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,058609 0,11099364 ! proline metabolic process GO:0006560 13 10 0,000 0,058609 0,11090766 ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,058609 0,11082182 ! V(D)J recombination GO:0033151 34 10 0,000 0,058609 0,11073611 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,058609 0,11065054 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,058609 0,11056509 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,058609 0,11047978 ! B cell proliferation GO:0042100 19 10 0,000 0,058609 0,1103946 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,058609 0,11030955 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,058609 0,11022463 ! multicellular organism growth GO:0035264 19 10 0,000 0,058609 0,11013984 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,058609 0,11005518 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,058609 0,10997065 ! epithelial cell development GO:0002064 21 10 0,000 0,058609 0,10988626 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,058609 0,10980199 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,058609 0,10971785 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,058609 0,10963384 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,058609 0,10954996 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,058609 0,1094662 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,058609 0,10938258 ! motor axon guidance GO:0008045 22 10 0,000 0,058609 0,10929908 ! copper ion homeostasis GO:0055070 13 10 0,000 0,058609 0,10921571 ! regulation of bone resorption GO:0045124 25 10 0,000 0,058609 0,10913246 ! protein heterooligomerization GO:0051291 17 10 0,000 0,058609 0,10904935 ! brain morphogenesis GO:0048854 23 10 0,000 0,058609 0,10896636 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,058609 0,10888349 ! segment specification GO:0007379 15 10 0,000 0,058609 0,10880075 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,058609 0,10871814 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,058609 0,10863565 ! blastoderm segmentation GO:0007350 19 10 0,000 0,058609 0,10855329 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,058609 0,10847105 ! DNA ligation GO:0006266 18 10 0,000 0,058609 0,10838894 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,058609 0,10830695 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,058609 0,10822509 ! melanosome localization GO:0032400 16 10 0,000 0,058609 0,10814335 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,058609 0,10806173 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,058609 0,10798024 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,058609 0,10789886 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,058609 0,10781761 ! induction of an organ GO:0001759 17 10 0,000 0,058609 0,10773649 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,058609 0,10765548 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,058609 0,1075746 ! protein sumoylation GO:0016925 17 10 0,000 0,058609 0,10749384 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,058609 0,1074132 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,058609 0,10733268 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,058609 0,10725228 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,058609 0,107172 ! salivary gland development GO:0007431 28 10 0,000 0,058609 0,10709184 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,058609 0,1070118 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,058609 0,10693188 ! midbrain development GO:0030901 14 10 0,000 0,058609 0,10685208 ! musculoskeletal movement GO:0050881 16 10 0,000 0,058609 0,1067724 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,058609 0,10669284 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,058609 0,1066134 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,058609 0,10653407 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,058609 0,10645486 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,058609 0,10637577 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,058609 0,1062968 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,058609 0,10621795 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,058609 0,10613921 ! detection of calcium ion GO:0005513 24 10 0,000 0,058609 0,10606059 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,058609 0,10598208 ! blastocyst formation GO:0001825 18 10 0,000 0,058609 0,10590369 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,058609 0,10582542 ! cerebellar cortex development GO:0021695 16 10 0,000 0,058609 0,10574726 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,058609 0,10566922 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,058609 0,10559129 ! response to nicotine GO:0035094 20 10 0,000 0,058609 0,10551348 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,058609 0,10543578 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,0602082 0,10823298 ! chromosome segregation GO:0007059 127 67 1,000 0,06182173 0,11105184 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,06182173 0,11097024 ! secondary metabolic process GO:0019748 125 67 1,000 0,06182173 0,11088877 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,06344993 0,11372574 ! extracellular matrix organization GO:0030198 146 68 1,000 0,06344993 0,11364237 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,06344993 0,11355911 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,06344993 0,11347598 ! cell projection assembly GO:0030031 138 68 1,000 0,06344993 0,11339297 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,06427844 0,11478963 ! respiratory burst GO:0045730 17 11 0,000 0,06427844 0,11470579 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,06427844 0,11462206 ! neuron fate specification GO:0048665 18 11 0,000 0,06427844 0,11453845 ! telencephalon cell migration GO:0022029 23 11 0,000 0,06427844 0,11445497 ! synapsis GO:0007129 14 11 0,000 0,06427844 0,11437161 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06427844 0,11428837 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,06427844 0,11420525 ! response to pain GO:0048265 27 11 0,000 0,06427844 0,11412225 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06427844 0,11403938 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06427844 0,11395662 ! blood vessel remodeling GO:0001974 30 11 0,000 0,06427844 0,11387398 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,06427844 0,11379146 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,06427844 0,11370907 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06427844 0,11362679 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,06427844 0,11354463 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06427844 0,11346259 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06427844 0,11338066 ! histidine metabolic process GO:0006547 22 11 0,000 0,06427844 0,11329886 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,06427844 0,11321717 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,06427844 0,11313561 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,06427844 0,11305415 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,06427844 0,11297282 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,06427844 0,1128916 ! UV protection GO:0009650 20 11 0,000 0,06427844 0,1128105 ! adult heart development GO:0007512 16 11 0,000 0,06427844 0,11272952 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,06427844 0,11264865 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06427844 0,1125679 ! macroautophagy GO:0016236 19 11 0,000 0,06427844 0,11248726 ! temperature homeostasis GO:0001659 18 11 0,000 0,06427844 0,11240674 ! behavioral fear response GO:0001662 27 11 0,000 0,06427844 0,11232634 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,06427844 0,11224605 ! negative regulation of ossification GO:0030279 27 11 0,000 0,06427844 0,11216587 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,06427844 0,11208581 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,06427844 0,11200586 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,06427844 0,11192603 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06427844 0,11184631 ! regulation of organ growth GO:0046620 14 11 0,000 0,06427844 0,1117667 ! pigment granule localization GO:0051875 20 11 0,000 0,06427844 0,11168721 ! vasoconstriction GO:0042310 20 11 0,000 0,06427844 0,11160783 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,06427844 0,11152857 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06427844 0,11144941 ! embryonic axis specification GO:0000578 19 11 0,000 0,06427844 0,11137037 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06427844 0,11129144 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06427844 0,11121262 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,06427844 0,11113391 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,06427844 0,11105532 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06427844 0,11097683 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06427844 0,11089846 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06427844 0,1108202 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06427844 0,11074205 ! prophase GO:0051324 17 11 0,000 0,06427844 0,110664 ! nucleosome positioning GO:0016584 15 11 0,000 0,06427844 0,11058607 ! regulation of isotype switching GO:0045191 24 11 0,000 0,06427844 0,11050825 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06427844 0,11043053 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06427844 0,11035293 ! apical protein localization GO:0045176 18 11 0,000 0,06427844 0,11027544 ! acid secretion GO:0046717 20 11 0,000 0,06427844 0,11019805 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06427844 0,11012077 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06427844 0,1100436 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,06427844 0,10996654 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,06427844 0,10988959 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,06427844 0,10981274 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06427844 0,109736 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,06427844 0,10965937 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06427844 0,10958285 ! oocyte development GO:0048599 20 11 0,000 0,06427844 0,10950643 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,06427844 0,10943012 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 19 11 0,000 0,06427844 0,10935391 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06427844 0,10927781 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,06427844 0,10920182 ! activation of innate immune response GO:0002218 16 11 0,000 0,06427844 0,10912593 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06427844 0,10905015 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06427844 0,10897448 ! lysogeny GO:0030069 22 11 0,000 0,06427844 0,1088989 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06427844 0,10882344 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,06427844 0,10874807 ! sequestering of metal ion GO:0051238 15 11 0,000 0,06427844 0,10867282 ! regulation of embryonic development GO:0045995 35 11 0,000 0,06427844 0,10859766 ! nucleus localization GO:0051647 22 11 0,000 0,06427844 0,10852261 ! negative regulation of cell size GO:0045792 144 69 1,000 0,06509256 0,10982122 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,06509256 0,10974543 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,06509256 0,10966974 ! urogenital system development GO:0001655 149 69 1,000 0,06509256 0,10959416 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,06509256 0,10951868 ! developmental maturation GO:0021700 128 69 1,000 0,06509256 0,1094433 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,06674938 0,11215181 ! germ cell development GO:0007281 133 70 1,000 0,06674938 0,11207473 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06991389 0,11730743 ! virus-host interaction GO:0019048 30 12 0,000 0,06991389 0,11722692 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,06991389 0,11714652 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,06991389 0,11706622 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06991389 0,11698604 ! protein complex disassembly GO:0043241 28 12 0,000 0,06991389 0,11690597 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06991389 0,11682601 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06991389 0,11674615 ! T cell proliferation GO:0042098 32 12 0,000 0,06991389 0,11666641 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06991389 0,11658677 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06991389 0,11650725 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06991389 0,11642783 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06991389 0,11634852 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06991389 0,11626931 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06991389 0,11619022 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06991389 0,11611123 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06991389 0,11603235 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06991389 0,11595358 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06991389 0,11587491 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06991389 0,11579635 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06991389 0,1157179 ! lipid digestion GO:0044241 21 12 0,000 0,06991389 0,11563955 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06991389 0,11556131 ! entry into host cell GO:0030260 34 12 0,000 0,06991389 0,11548318 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06991389 0,11540515 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06991389 0,11532723 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06991389 0,11524941 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06991389 0,11517169 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06991389 0,11509409 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06991389 0,11501658 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06991389 0,11493918 GO:0016180|snRNA processing, ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06991389 0,11486188 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06991389 0,11478469 ! cranial nerve development GO:0021545 23 12 0,000 0,06991389 0,1147076 ! fucose catabolic process GO:0019317 25 12 0,000 0,06991389 0,11463062 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06991389 0,11455374 ! histone acetylation GO:0016573 27 12 0,000 0,06991389 0,11447696 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06991389 0,11440028 ! zymogen activation GO:0031638 18 12 0,000 0,06991389 0,11432371 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06991389 0,11424724 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06991389 0,11417087 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06991389 0,1140946 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06991389 0,11401844 ! oocyte differentiation GO:0009994 21 12 0,000 0,06991389 0,11394238 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06991389 0,11386641 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06991389 0,11379055 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,06991389 0,1137148 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06991389 0,11363914 ! defense response to fungus GO:0050832 15 12 0,000 0,06991389 0,11356358 ! developmental induction GO:0031128 22 12 0,000 0,06991389 0,11348812 GO:0045168|cell-cell signaling involved in cell fate specification, ! response to cold GO:0009409 17 12 0,000 0,06991389 0,11341276 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06991389 0,11333751 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06991389 0,11326235 ! localization within membrane GO:0051668 26 12 0,000 0,06991389 0,11318729 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,0701047 0,11342104 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,0701047 0,11334598 ! regulation of immune effector process GO:0002697 156 73 1,000 0,07180274 0,11601461 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,07351408 0,11870119 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,07523849 0,12140531 ! eye development GO:0001654 155 75 1,000 0,07523849 0,12132517 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07551555 0,12169162 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07551555 0,1216114 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07551555 0,12153129 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07551555 0,12145128 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 28 13 0,000 0,07551555 0,12137138 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07551555 0,12129158 ! cartilage condensation GO:0001502 22 13 0,000 0,07551555 0,12121189 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07551555 0,1211323 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07551555 0,12105282 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07551555 0,12097344 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07551555 0,12089416 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07551555 0,12081499 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07551555 0,12073593 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07551555 0,12065696 ! methionine metabolic process GO:0006555 31 13 0,000 0,07551555 0,1205781 ! plasma membrane organization GO:0007009 27 13 0,000 0,07551555 0,12049934 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07551555 0,12042069 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07551555 0,12034214 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07551555 0,12026369 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07551555 0,12018534 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,07551555 0,12010709 ! cytokine metabolic process GO:0042107 24 13 0,000 0,07551555 0,12002895 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,07551555 0,11995091 ! exocrine system development GO:0035272 34 13 0,000 0,07551555 0,11987297 ! asymmetric protein localization GO:0008105 24 13 0,000 0,07551555 0,11979513 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,07551555 0,11971739 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,07551555 0,11963975 ! L-glutamate transport GO:0015813 30 13 0,000 0,07551555 0,11956221 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,07551555 0,11948478 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07551555 0,11940744 ! protein homotetramerization GO:0051289 24 13 0,000 0,07551555 0,1193302 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07551555 0,11925307 ! regulation of DNA repair GO:0006282 23 13 0,000 0,07551555 0,11917603 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07551555 0,11909909 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07551555 0,11902225 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07551555 0,11894552 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07551555 0,11886888 ! histone methylation GO:0016571 29 13 0,000 0,07551555 0,11879233 ! chromatin silencing GO:0006342 29 13 0,000 0,07551555 0,11871589 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07551555 0,11863955 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07551555 0,1185633 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07551555 0,11848715 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,07551555 0,1184111 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07551555 0,11833515 ! spleen development GO:0048536 24 13 0,000 0,07551555 0,11825929 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,07551555 0,11818353 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,07551555 0,11810787 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07551555 0,11803231 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07551555 0,11795684 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07551555 0,11788147 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07551555 0,11780619 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07551555 0,11773101 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,07551555 0,11765593 ! insulin secretion GO:0030073 24 13 0,000 0,07551555 0,11758094 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,07551555 0,11750605 ! acrosome reaction GO:0007340 19 13 0,000 0,07551555 0,11743125 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07551555 0,11735655 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07551555 0,11728194 ! neurotransmitter transport GO:0006836 142 77 1,000 0,07872567 0,12218985 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,07872567 0,12211227 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,07872567 0,12203478 ! rRNA transcription GO:0009303 28 14 0,000 0,08108364 0,12561023 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,08108364 0,12553063 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,08108364 0,12545113 ! water transport GO:0006833 21 14 0,000 0,08108364 0,12537173 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,08108364 0,12529243 ! non-recombinational repair GO:0000726 29 14 0,000 0,08108364 0,12521323 GO:0006303|double-strand break repair via nonhomologous end joining, ! retina development in camera-type eye GO:0060041 28 14 0,000 0,08108364 0,12513413 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,08108364 0,12505513 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,08108364 0,12497623 ! regulated secretory pathway GO:0045055 24 14 0,000 0,08108364 0,12489743 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,08108364 0,12481873 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,08108364 0,12474013 ! arginine metabolic process GO:0006525 21 14 0,000 0,08108364 0,12466163 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,08108364 0,12458323 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,08108364 0,12450492 ! regulation of heart rate GO:0002027 25 14 0,000 0,08108364 0,12442671 ! fear response GO:0042596 34 14 0,000 0,08108364 0,12434861 ! organic alcohol transport GO:0015850 29 14 0,000 0,08108364 0,1242706 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,08108364 0,12419268 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,08108364 0,12411487 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08108364 0,12403715 ! neutral amino acid transport GO:0015804 28 14 0,000 0,08108364 0,12395953 ! bone mineralization GO:0030282 18 14 0,000 0,08108364 0,12388201 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,08108364 0,12380458 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,08108364 0,12372725 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,08108364 0,12365002 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,08108364 0,12357288 ! regulation of cellular pH GO:0030641 27 14 0,000 0,08108364 0,12349584 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,08108364 0,1234189 ! ribosome assembly GO:0042255 18 14 0,000 0,08108364 0,12334205 ! cerebellum development GO:0021549 23 14 0,000 0,08108364 0,1232653 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,08108364 0,12318864 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,08108364 0,12311208 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,08108364 0,12303561 ! response to gamma radiation GO:0010332 30 14 0,000 0,08108364 0,12295924 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,08108364 0,12288296 ! NADP metabolic process GO:0006739 24 14 0,000 0,08108364 0,12280678 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,08108364 0,12273069 ! oxygen transport GO:0015671 22 14 0,000 0,08108364 0,12265469 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08108364 0,12257879 ! male genitalia development GO:0030539 26 14 0,000 0,08108364 0,12250299 ! regulation of RNA stability GO:0043487 33 14 0,000 0,08108364 0,12242727 ! regulation of axon extension GO:0030516 43 14 0,000 0,08108364 0,12235165 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,08108364 0,12227613 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,08108364 0,1222007 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,08226257 0,12390102 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,08226257 0,12382468 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,08404913 0,12643597 ! meiosis GO:0007126 143 81 1,000 0,08584749 0,12906179 GO:0051327|M phase of meiotic cell cycle, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08661834 0,1301406 ! lactation GO:0007595 30 15 0,000 0,08661834 0,13006061 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,08661834 0,12998072 ! reproductive cellular process GO:0048610 22 15 0,000 0,08661834 0,12990093 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08661834 0,12982124 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 22 15 0,000 0,08661834 0,12974164 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08661834 0,12966214 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,08661834 0,12958274 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08661834 0,12950344 ! copper ion transport GO:0006825 22 15 0,000 0,08661834 0,12942423 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,08661834 0,12934512 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08661834 0,12926611 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08661834 0,12918719 ! sulfate transport GO:0008272 27 15 0,000 0,08661834 0,12910837 ! response to cAMP GO:0051591 25 15 0,000 0,08661834 0,12902964 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08661834 0,12895102 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08661834 0,12887248 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,08661834 0,12879404 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08661834 0,1287157 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08661834 0,12863746 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08661834 0,1285593 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,08661834 0,12848125 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,08661834 0,12840329 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08661834 0,12832542 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08661834 0,12824765 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,08661834 0,12816997 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08661834 0,12809238 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08661834 0,12801489 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08661834 0,12793749 ! histone deacetylation GO:0016575 24 15 0,000 0,08661834 0,12786019 ! water homeostasis GO:0030104 28 15 0,000 0,08661834 0,12778298 ! cofactor transport GO:0051181 30 15 0,000 0,08661834 0,12770586 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08661834 0,12762884 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08661834 0,12755191 ! intestinal absorption GO:0050892 31 15 0,000 0,08661834 0,12747507 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08661834 0,12739832 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08661834 0,12732167 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08661834 0,12724511 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,08661834 0,12716864 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08661834 0,12709226 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08661834 0,12701598 ! meiotic cell cycle GO:0051321 144 82 1,000 0,08765745 0,12846259 ! exocytosis GO:0006887 153 83 1,000 0,08947879 0,13105317 ! response to drug GO:0042493 149 83 1,000 0,08947879 0,13097465 ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,08947879 0,13089622 ! T cell activation GO:0042110 189 84 1,000 0,09131133 0,13349705 ! regulation of ligase activity GO:0051340 147 84 1,000 0,09131133 0,13341721 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,09211987 0,13451814 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,09211987 0,13443778 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,09211987 0,13435752 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,09211987 0,13427735 ! bone remodeling GO:0046849 28 16 0,000 0,09211987 0,13419728 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,09211987 0,13411731 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,09211987 0,13403743 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,09211987 0,13395764 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,09211987 0,13387795 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,09211987 0,13379836 ! startle response GO:0001964 28 16 0,000 0,09211987 0,13371886 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,09211987 0,13363945 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,09211987 0,13356014 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,09211987 0,13348093 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,09211987 0,1334018 ! protein polyubiquitination GO:0000209 41 16 0,000 0,09211987 0,13332277 ! glutamate metabolic process GO:0006536 25 16 0,000 0,09211987 0,13324384 ! pituitary gland development GO:0021983 30 16 0,000 0,09211987 0,13316499 ! response to osmotic stress GO:0006970 27 16 0,000 0,09211987 0,13308625 ! lysosomal transport GO:0007041 31 16 0,000 0,09211987 0,13300759 ! fructose metabolic process GO:0006000 25 16 0,000 0,09211987 0,13292903 ! L-amino acid transport GO:0015807 33 16 0,000 0,09211987 0,13285056 ! stem cell development GO:0048864 46 16 0,000 0,09211987 0,13277218 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09211987 0,13269389 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09211987 0,1326157 ! intermediate filament-based process GO:0045103 36 16 0,000 0,09211987 0,1325376 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,09211987 0,13245959 ! negative regulation of immune response GO:0050777 38 16 0,000 0,09211987 0,13238167 ! axon cargo transport GO:0008088 46 16 0,000 0,09211987 0,13230385 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,09211987 0,13222611 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,09211987 0,13214847 ! DNA replication initiation GO:0006270 28 16 0,000 0,09211987 0,13207092 ! neuron recognition GO:0008038 40 16 0,000 0,09211987 0,13199346 ! mRNA splice site selection GO:0006376 44 16 0,000 0,09211987 0,13191608 ! tissue regeneration GO:0042246 27 16 0,000 0,09211987 0,13183881 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,09211987 0,13176162 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,09211987 0,13168452 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,09211987 0,13160751 ! biomineral formation GO:0031214 22 16 0,000 0,09211987 0,13153059 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,09211987 0,13145376 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,09211987 0,13137702 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,09211987 0,13130037 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09211987 0,13122381 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,09211987 0,13114734 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,09211987 0,13107096 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,09211987 0,13099467 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09211987 0,13091846 ! peptide hormone processing GO:0016486 27 16 0,000 0,09211987 0,13084235 ! negative regulation of growth GO:0045926 168 85 1,000 0,09315486 0,13223551 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,09315486 0,13215872 ! metencephalon development GO:0022037 32 17 0,000 0,09758841 0,13836825 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,09758841 0,13828799 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,09758841 0,13820782 ! filopodium assembly GO:0046847 42 17 0,000 0,09758841 0,13812775 ! endothelial cell migration GO:0043542 31 17 0,000 0,09758841 0,13804776 ! gene silencing by RNA GO:0031047 38 17 0,000 0,09758841 0,13796788 ! glial cell development GO:0021782 28 17 0,000 0,09758841 0,13788808 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09758841 0,13780837 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,09758841 0,13772876 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,09758841 0,13764924 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09758841 0,13756981 ! myoblast differentiation GO:0045445 50 17 0,000 0,09758841 0,13749048 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,09758841 0,13741123 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09758841 0,13733208 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09758841 0,13725302 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,09758841 0,13717404 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,09758841 0,13709516 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,09758841 0,13701637 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09758841 0,13693767 ! regulation of protein binding GO:0043393 33 17 0,000 0,09758841 0,13685906 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,09758841 0,13678054 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09758841 0,13670211 ! genitalia development GO:0048806 32 17 0,000 0,09758841 0,13662378 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09758841 0,13654553 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,09758841 0,13646737 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,09758841 0,1363893 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09758841 0,13631131 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,09758841 0,13623342 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09758841 0,13615562 ! steroid catabolic process GO:0006706 34 17 0,000 0,09758841 0,1360779 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,09758841 0,13600028 ! gas transport GO:0015669 26 17 0,000 0,09758841 0,13592274 ! organic cation transport GO:0015695 32 17 0,000 0,09758841 0,13584529 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,09758841 0,13576793 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,09758841 0,13569066 ! tube morphogenesis GO:0035239 194 89 1,000 0,10063496 0,1398471 ! response to unfolded protein GO:0006986 139 90 1,000 0,10253052 0,14240027 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,10253052 0,14231936 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,10302417 0,14292336 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,10302417 0,14284225 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10302417 0,14276122 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,10302417 0,14268029 ! adult walking behavior GO:0007628 36 18 0,000 0,10302417 0,14259946 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,10302417 0,14251871 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,10302417 0,14243805 ! centrosome cycle GO:0007098 26 18 0,000 0,10302417 0,14235749 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,10302417 0,14227701 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,10302417 0,14219663 ! glycine metabolic process GO:0006544 30 18 0,000 0,10302417 0,14211634 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10302417 0,14203614 ! response to retinoic acid GO:0032526 31 18 0,000 0,10302417 0,14195603 ! DNA integration GO:0015074 32 18 0,000 0,10302417 0,14187601 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,10302417 0,14179608 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,10302417 0,14171624 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,10302417 0,14163649 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,10302417 0,14155683 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,10302417 0,14147726 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,10302417 0,14139777 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,10302417 0,14131838 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,10302417 0,14123908 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,10302417 0,14115986 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,10302417 0,14108074 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,10302417 0,1410017 ! detection of bacterium GO:0016045 22 18 0,000 0,10302417 0,14092275 ! nerve development GO:0021675 34 18 0,000 0,10302417 0,14084389 ! defense response to virus GO:0051607 43 18 0,000 0,10302417 0,14076512 ! microspike assembly GO:0030035 46 18 0,000 0,10302417 0,14068644 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,10302417 0,14060784 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,10302417 0,14052933 ! defense response to bacterium GO:0042742 112 91 1,000 0,10443592 0,14237553 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,10635097 0,14490542 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,10827549 0,14744538 GO:0010498|proteasomal protein catabolic process, ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,10842733 0,1475699 ! positive regulation of translation GO:0045727 31 19 0,000 0,10842733 0,14748773 ! negative regulation of defense response GO:0031348 27 19 0,000 0,10842733 0,14740566 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,10842733 0,14732368 ! neuron maturation GO:0042551 46 19 0,000 0,10842733 0,14724178 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,10842733 0,14715998 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,10842733 0,14707827 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,10842733 0,14699665 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,10842733 0,14691512 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,10842733 0,14683369 ! inositol metabolic process GO:0006020 33 19 0,000 0,10842733 0,14675234 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10842733 0,14667108 ! memory GO:0007613 34 19 0,000 0,10842733 0,14658991 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,10842733 0,14650883 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,10842733 0,14642784 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,10842733 0,14634694 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,10842733 0,14626613 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,10842733 0,14618541 ! cerebral cortex development GO:0021987 40 19 0,000 0,10842733 0,14610478 ! response to vitamin A GO:0033189 32 19 0,000 0,10842733 0,14602424 ! heme metabolic process GO:0042168 40 19 0,000 0,10842733 0,14594378 ! neuromuscular junction development GO:0007528 43 19 0,000 0,10842733 0,14586342 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,10842733 0,14578314 ! response to fungus GO:0009620 26 19 0,000 0,10842733 0,14570295 ! peptide cross-linking GO:0018149 39 19 0,000 0,10842733 0,14562285 ! protein export from nucleus GO:0006611 40 19 0,000 0,10842733 0,14554284 ! heart process GO:0003015 32 19 0,000 0,10842733 0,14546292 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,10842733 0,14538308 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,10842733 0,14530333 ! visual learning GO:0008542 38 19 0,000 0,10842733 0,14522367 ! cellular pigmentation GO:0033059 37 19 0,000 0,10842733 0,14514409 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,10842733 0,14506461 ! vitamin transport GO:0051180 31 19 0,000 0,10842733 0,14498521 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,10842733 0,14490589 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,10842733 0,14482666 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,10842733 0,14474752 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,10842733 0,14466847 ! cilium assembly GO:0042384 38 19 0,000 0,10842733 0,1445895 ! peptide hormone secretion GO:0030072 32 19 0,000 0,10842733 0,14451062 ! female pregnancy GO:0007565 166 94 1,000 0,11020929 0,1468055 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,11020929 0,1467255 ! regulation of membrane potential GO:0042391 179 94 1,000 0,11020929 0,14664558 ! regulation of defense response GO:0031347 171 95 1,000 0,11215219 0,1491496 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,11215219 0,14906845 ! protein secretion GO:0009306 45 20 0,000 0,1137981 0,15117388 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,1137981 0,15109172 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,1137981 0,15100965 ! positive regulation of ossification GO:0045778 50 20 0,000 0,1137981 0,15092766 ! skin development GO:0043588 42 20 0,000 0,1137981 0,15084577 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,1137981 0,15076397 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,1137981 0,15068225 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,1137981 0,15060063 ! response to vitamin GO:0033273 36 20 0,000 0,1137981 0,15051909 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,1137981 0,15043764 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,1137981 0,15035628 ! bile acid metabolic process GO:0008206 34 20 0,000 0,1137981 0,150275 ! response to alkaloid GO:0043279 38 20 0,000 0,1137981 0,15019382 ! retinoid metabolic process GO:0001523 34 20 0,000 0,1137981 0,15011272 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,1137981 0,15003171 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,1137981 0,14995079 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,1137981 0,14986995 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,1137981 0,1497892 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,1137981 0,14970854 ! peptide secretion GO:0002790 38 20 0,000 0,1137981 0,14962796 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,1137981 0,14954748 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,1137981 0,14946707 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,1137981 0,14938676 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,1137981 0,14930653 ! cell-cell junction organization GO:0045216 43 20 0,000 0,1137981 0,14922639 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,1137981 0,14914633 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,1137981 0,14906636 ! regulation of glucose import GO:0046324 30 20 0,000 0,1137981 0,14898647 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,1137981 0,14890667 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,1137981 0,14882696 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,1137981 0,14874733 ! negative regulation of translation GO:0017148 32 20 0,000 0,1137981 0,14866778 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,1137981 0,14858833 ! response to protein stimulus GO:0051789 158 96 1,000 0,11410403 0,14890819 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,11913667 0,15539288 ! hormone secretion GO:0046879 39 21 0,000 0,11913667 0,15530996 ! cAMP metabolic process GO:0046058 41 21 0,000 0,11913667 0,15522713 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,11913667 0,15514439 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,11913667 0,15506173 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,11913667 0,15497917 ! ovarian follicle development GO:0001541 39 21 0,000 0,11913667 0,15489669 ! smooth muscle contraction GO:0006939 48 21 0,000 0,11913667 0,15481429 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,11913667 0,15473199 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,11913667 0,15464977 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,11913667 0,15456764 ! plasma membrane fusion GO:0045026 33 21 0,000 0,11913667 0,1544856 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,11913667 0,15440365 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,11913667 0,15432178 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,11913667 0,15424 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,11913667 0,1541583 ! diencephalon development GO:0021536 36 21 0,000 0,11913667 0,15407669 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,11913667 0,15399517 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,11913667 0,15391374 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,11913667 0,15383239 ! collagen catabolic process GO:0030574 29 21 0,000 0,11913667 0,15375112 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,11913667 0,15366994 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,11913667 0,15358885 ! sperm-egg recognition GO:0035036 23 21 0,000 0,11913667 0,15350784 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,11913667 0,15342692 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,12199711 0,15702789 GO:0060538|skeletal muscle organ development, ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,12444322 0,16009204 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,12444322 0,16000778 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,12444322 0,15992361 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,12444322 0,15983953 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,12444322 0,15975554 ! microtubule-based transport GO:0010970 59 22 0,000 0,12444322 0,15967163 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,12444322 0,15958781 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,12444322 0,15950409 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,12444322 0,15942044 ! cellular response to starvation GO:0009267 37 22 0,000 0,12444322 0,15933689 ! vacuolar transport GO:0007034 41 22 0,000 0,12444322 0,15925342 ! central nervous system neuron development GO:0021954 47 22 0,000 0,12444322 0,15917005 ! fucose metabolic process GO:0006004 44 22 0,000 0,12444322 0,15908675 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,12444322 0,15900355 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,12444322 0,15892043 ! ureteric bud development GO:0001657 50 22 0,000 0,12444322 0,1588374 ! cell aging GO:0007569 48 22 0,000 0,12444322 0,15875446 ! stem cell differentiation GO:0048863 57 22 0,000 0,12444322 0,1586716 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,12444322 0,15858883 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,12444322 0,15850615 ! renal system process GO:0003014 42 22 0,000 0,12444322 0,15842355 ! vasodilation GO:0042311 40 22 0,000 0,12444322 0,15834103 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,12444322 0,15825861 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,12444322 0,15817627 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,12444322 0,15809401 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,12444322 0,15801184 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,12444322 0,15792976 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,12444322 0,15784776 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,12444322 0,15776585 ! sarcomere organization GO:0045214 32 22 0,000 0,12444322 0,15768402 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,12444322 0,15760227 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,12444322 0,15752061 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,12444322 0,15743904 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,12444322 0,15735755 ! gut development GO:0048565 44 22 0,000 0,12444322 0,15727614 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,12444322 0,15719482 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,12444322 0,15711358 ! protein stabilization GO:0050821 41 22 0,000 0,12444322 0,15703243 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,12971796 0,16360401 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,12971796 0,16351959 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,12971796 0,16343526 ! gluconeogenesis GO:0006094 38 23 0,000 0,12971796 0,16335101 ! glycerol metabolic process GO:0006071 40 23 0,000 0,12971796 0,16326685 ! viral genome replication GO:0019079 44 23 0,000 0,12971796 0,16318278 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,12971796 0,1630988 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,12971796 0,1630149 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,12971796 0,16293109 ! regeneration GO:0031099 42 23 0,000 0,12971796 0,16284736 ! axis specification GO:0009798 43 23 0,000 0,12971796 0,16276372 ! visual behavior GO:0007632 46 23 0,000 0,12971796 0,16268017 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,12971796 0,1625967 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,12971796 0,16251332 ! response to ethanol GO:0045471 47 23 0,000 0,12971796 0,16243002 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,12971796 0,16234681 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,12971796 0,16226368 ! peroxisome organization GO:0007031 43 23 0,000 0,12971796 0,16218064 ! lysosome organization GO:0007040 47 23 0,000 0,12971796 0,16209768 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,12971796 0,16201481 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,12971796 0,16193202 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,12971796 0,16184932 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,12971796 0,1617667 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,12971796 0,16168417 ! DNA modification GO:0006304 36 23 0,000 0,12971796 0,16160172 ! fatty acid transport GO:0015908 47 23 0,000 0,12971796 0,16151935 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,12971796 0,16143707 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,12971796 0,16135487 ! hormone transport GO:0009914 41 23 0,000 0,12971796 0,16127276 ! cell-cell recognition GO:0009988 28 23 0,000 0,12971796 0,16119073 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,12971796 0,16110878 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,12971796 0,16102691 GO:0006099|tricarboxylic acid cycle, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,13496106 0,16745042 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,13496106 0,16736542 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,13496106 0,1672805 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,13496106 0,16719568 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,13496106 0,16711093 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,13496106 0,16702628 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,13496106 0,16694171 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,13496106 0,16685722 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,13496106 0,16677282 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,13496106 0,16668851 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,13496106 0,16660428 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,13496106 0,16652014 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,13496106 0,16643608 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,13496106 0,16635211 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,13496106 0,16626822 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,13496106 0,16618441 ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,13496106 0,16610069 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,13496106 0,16601706 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,13496106 0,1659335 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,13496106 0,16585004 ! oogenesis GO:0048477 44 24 0,000 0,13496106 0,16576665 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,13496106 0,16568335 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,13496106 0,16560014 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,13496106 0,165517 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,13496106 0,16543396 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,13496106 0,16535099 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,13496106 0,16526811 ! regulation of amine transport GO:0051952 41 24 0,000 0,13496106 0,16518531 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,14017273 0,1714782 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,14017273 0,17139238 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,14017273 0,17130664 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,14017273 0,17122098 ! leukocyte adhesion GO:0007159 55 25 0,000 0,14017273 0,17113542 ! phototransduction GO:0007602 37 25 0,000 0,14017273 0,17104993 ! keratinization GO:0031424 37 25 0,000 0,14017273 0,17096454 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,14017273 0,17087923 ! vacuole organization GO:0007033 49 25 0,000 0,14017273 0,170794 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,14017273 0,17070886 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,14017273 0,1706238 ! chromosome condensation GO:0030261 48 25 0,000 0,14017273 0,17053883 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,14017273 0,17045394 ! regulation of behavior GO:0050795 48 25 0,000 0,14017273 0,17036914 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,14017273 0,17028442 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,14017273 0,17019979 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,14017273 0,17011524 ! immunoglobulin production GO:0002377 62 25 0,000 0,14017273 0,17003077 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,14017273 0,16994639 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,14017273 0,16986209 ! protein tetramerization GO:0051262 57 25 0,000 0,14017273 0,16977787 ! myelination GO:0042552 50 26 0,000 0,14535314 0,17596517 ! initiation of viral infection GO:0019059 60 26 0,000 0,14535314 0,17587802 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,14535314 0,17579095 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,14535314 0,17570397 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,14535314 0,17561707 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,14535314 0,17553026 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,14535314 0,17544354 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,14535314 0,1753569 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,14535314 0,17527034 ! digestive system process GO:0022600 49 26 0,000 0,14535314 0,17518388 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,14535314 0,17509749 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 0,000 0,14535314 0,1750112 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,14535314 0,17492498 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,14535314 0,17483886 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,14535314 0,17475281 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,14535314 0,17466685 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,14535314 0,17458098 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,14535314 0,17449519 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,14535314 0,17440949 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,14535314 0,17432387 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,14535314 0,17423833 ! blastocyst development GO:0001824 50 26 0,000 0,14535314 0,17415288 ! telomere organization GO:0032200 46 26 0,000 0,14535314 0,17406751 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,14535314 0,17398222 ! neural tube closure GO:0001843 58 26 0,000 0,14535314 0,17389702 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,14535314 0,1738119 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,14535314 0,17372687 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,15050248 0,17979343 ! embryonic pattern specification GO:0009880 49 27 0,000 0,15050248 0,17970555 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,15050248 0,17961776 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,15050248 0,17953006 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,15050248 0,17944244 ! iron ion transport GO:0006826 65 27 0,000 0,15050248 0,17935491 ! superoxide metabolic process GO:0006801 41 27 0,000 0,15050248 0,17926746 ! tube lumen formation GO:0035148 59 27 0,000 0,15050248 0,1791801 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,15050248 0,17909282 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,15050248 0,17900563 ! response to starvation GO:0042594 47 27 0,000 0,15050248 0,17891852 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,15050248 0,1788315 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,15050248 0,17874456 ! leukocyte proliferation GO:0070661 59 27 0,000 0,15050248 0,17865771 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,15050248 0,17857094 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,15562095 0,18455435 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,15562095 0,18446481 ! protein amino acid acylation GO:0043543 59 28 0,000 0,15562095 0,18437535 ! circadian rhythm GO:0007623 56 28 0,000 0,15562095 0,18428598 ! dendrite development GO:0016358 67 28 0,000 0,15562095 0,18419669 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,15562095 0,18410749 ! sperm motility GO:0030317 37 28 0,000 0,15562095 0,18401838 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,15562095 0,18392935 ! base-excision repair GO:0006284 41 28 0,000 0,15562095 0,18384041 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,15562095 0,18375156 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,15562095 0,18366279 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,15562095 0,1835741 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,15562095 0,18348551 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,15562095 0,183397 ! glutathione metabolic process GO:0006749 42 28 0,000 0,15562095 0,18330857 ! lipid oxidation GO:0034440 48 28 0,000 0,15562095 0,18322023 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,15562095 0,18313197 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,16070871 0,18902811 ! translational initiation GO:0006413 66 29 0,000 0,16070871 0,18893714 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,16070871 0,18884626 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,16070871 0,18875547 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,16070871 0,18866477 ! autophagy GO:0006914 47 29 0,000 0,16070871 0,18857415 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,16070871 0,18848362 ! primary neural tube formation GO:0014020 61 29 0,000 0,16070871 0,18839318 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,16070871 0,18830282 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,16070871 0,18821255 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,16070871 0,18812237 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,16070871 0,18803227 ! somitogenesis GO:0001756 52 29 0,000 0,16070871 0,18794226 ! synaptogenesis GO:0007416 46 29 0,000 0,16070871 0,18785234 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,16070871 0,1877625 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,16070871 0,18767275 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,16070871 0,18758308 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,16576597 0,19339363 ! phenol metabolic process GO:0018958 56 30 0,000 0,16576597 0,19330131 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,16576597 0,19320909 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,16576597 0,19311695 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,16576597 0,19302491 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,16576597 0,19293295 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,16576597 0,19284107 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,16576597 0,19274929 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,16576597 0,19265759 ! myofibril assembly GO:0030239 50 30 0,000 0,16576597 0,19256598 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,16576597 0,19247446 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,16576597 0,19238302 ! cell fate determination GO:0001709 64 30 0,000 0,16576597 0,19229167 ! phospholipid transport GO:0015914 65 30 0,000 0,16576597 0,1922004 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,16576597 0,19210923 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,16576597 0,19201814 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,16576597 0,19192713 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,16576597 0,19183622 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,16576597 0,19174539 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,17079289 0,19746665 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,17079289 0,19737324 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,17079289 0,19727992 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,17079289 0,19718668 ! ovulation cycle process GO:0022602 55 31 0,000 0,17079289 0,19709354 ! male gonad development GO:0008584 56 31 0,000 0,17079289 0,19700048 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,17079289 0,19690751 ! detection of light stimulus GO:0009583 44 31 0,000 0,17079289 0,19681463 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,17079289 0,19672184 ! natural killer cell activation GO:0030101 50 31 0,000 0,17079289 0,19662913 ! ensheathment of neurons GO:0007272 64 31 0,000 0,17079289 0,19653652 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,17079289 0,19644398 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,17079289 0,19635154 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,17079289 0,19625918 ! eye morphogenesis GO:0048592 65 31 0,000 0,17079289 0,19616691 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,17578966 0,20181115 ! metanephros development GO:0001656 81 32 0,000 0,17578966 0,20171636 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,17578966 0,20162166 ! muscle cell development GO:0055001 52 32 0,000 0,17578966 0,20152705 ! mesoderm formation GO:0001707 73 32 0,000 0,17578966 0,20143252 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,17578966 0,20133808 ! ovulation cycle GO:0042698 57 32 0,000 0,17578966 0,20124374 ! peripheral nervous system development GO:0007422 68 32 0,000 0,17578966 0,20114948 ! BMP signaling pathway GO:0030509 71 32 0,000 0,17578966 0,20105531 ! hindbrain development GO:0030902 65 32 0,000 0,17578966 0,20096122 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,17578966 0,20086723 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,17578966 0,20077332 ! gene silencing GO:0016458 71 32 0,000 0,17578966 0,2006795 ! regulation of pH GO:0006885 56 33 0,000 0,18075646 0,20625317 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,18075646 0,20615688 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,18075646 0,20606067 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,18075646 0,20596456 ! response to ionizing radiation GO:0010212 74 33 0,000 0,18075646 0,20586854 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,18075646 0,20577261 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,18075646 0,20567677 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,18075646 0,20558102 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,18075646 0,20548535 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,18075646 0,20538978 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,18569347 0,21090151 ! glial cell differentiation GO:0010001 67 34 0,000 0,18569347 0,2108035 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,18569347 0,21070559 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,18569347 0,21060777 ! spliceosome assembly GO:0000245 75 34 0,000 0,18569347 0,21051004 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,18569347 0,2104124 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,18569347 0,21031485 ! formation of primary germ layer GO:0001704 76 34 0,000 0,18569347 0,2102174 ! cell fate specification GO:0001708 56 34 0,000 0,18569347 0,21012003 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,18569347 0,21002275 ! adult locomotory behavior GO:0008344 62 34 0,000 0,18569347 0,20992556 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,19060086 0,21537368 ! negative regulation of secretion GO:0051048 68 35 0,000 0,19060086 0,21527411 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,19060086 0,21517463 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,19060086 0,21507524 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,19060086 0,21497595 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,19060086 0,21487674 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,19060086 0,21477763 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,19060086 0,21467861 ! ceramide metabolic process GO:0006672 72 35 0,000 0,19060086 0,21457968 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,19060086 0,21448084 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,19060086 0,21438209 ! regulation of muscle development GO:0048634 82 36 0,000 0,19547882 0,21976749 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,19547882 0,2196664 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,19547882 0,21956541 ! positive regulation of cell development GO:0010720 85 36 0,000 0,19547882 0,2194645 ! protein targeting to membrane GO:0006612 75 36 0,000 0,19547882 0,21936369 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,19547882 0,21926297 ! aerobic respiration GO:0009060 56 36 0,000 0,19547882 0,21916235 ! cytokine production GO:0001816 68 36 0,000 0,19547882 0,21906181 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,19547882 0,21896137 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,19547882 0,21886103 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,20032752 0,22418696 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,20032752 0,22408431 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,20032752 0,22398175 ! odontogenesis GO:0042476 74 37 0,000 0,20032752 0,22387929 ! actomyosin structure organization GO:0031032 68 37 0,000 0,20032752 0,22377692 ! female gonad development GO:0008585 71 37 0,000 0,20032752 0,22367465 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,20032752 0,22357246 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,20032752 0,22347038 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,20032752 0,22336838 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,20514713 0,22863797 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,20514713 0,22853371 ! organic anion transport GO:0015711 82 38 0,000 0,20514713 0,22842955 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,20514713 0,22832548 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,20514713 0,22822151 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,20514713 0,22811763 ! regulation of protein stability GO:0031647 77 38 0,000 0,20514713 0,22801385 ! spermatid development GO:0007286 69 38 0,000 0,20514713 0,22791016 ! pigment metabolic process GO:0042440 87 38 0,000 0,20514713 0,22780656 ! neural tube formation GO:0001841 79 38 0,000 0,20514713 0,22770306 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,20993783 0,23291467 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,20993783 0,23280895 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,20993783 0,23270332 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,20993783 0,23259778 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,20993783 0,23249234 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,20993783 0,232387 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,21469978 0,23755053 ! learning GO:0007612 82 40 0,000 0,21469978 0,23744299 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,21469978 0,23733555 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,21469978 0,23722821 ! mismatch repair GO:0006298 58 40 0,000 0,21469978 0,23712096 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,21469978 0,23701381 ! mRNA catabolic process GO:0006402 79 41 0,000 0,21943317 0,24212974 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,21943317 0,24202042 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,21943317 0,24191121 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,21943317 0,24180209 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,21943317 0,24169307 ! gliogenesis GO:0042063 91 41 0,000 0,21943317 0,24158415 ! feeding behavior GO:0007631 69 41 0,000 0,21943317 0,24147533 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,21943317 0,24136661 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,21943317 0,24125798 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,21943317 0,24114946 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,21943317 0,24104102 ! ear morphogenesis GO:0042471 64 42 0,000 0,22413816 0,24609867 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,22413816 0,24598811 ! T cell differentiation GO:0030217 93 42 0,000 0,22413816 0,24587765 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,22413816 0,24576729 ! regulation of protein secretion GO:0050708 77 42 0,000 0,22413816 0,24565704 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,22413816 0,24554688 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,22413816 0,24543681 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,22881493 0,25044573 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,22881493 0,25033357 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,22881493 0,25022151 ! regulation of tube size GO:0035150 76 43 0,000 0,22881493 0,25010956 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,22881493 0,2499977 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,22881493 0,24988595 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,22881493 0,24977429 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,22881493 0,24966273 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,22881493 0,24955128 ! segmentation GO:0035282 78 43 0,000 0,22881493 0,24943992 ! ion transmembrane transport GO:0034220 79 43 0,000 0,22881493 0,24932866 ! neuron migration GO:0001764 85 43 0,000 0,22881493 0,2492175 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,23346363 0,2541674 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,23346363 0,25405418 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,23346363 0,25394107 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,23346363 0,25382806 ! striated muscle contraction GO:0006941 85 44 0,000 0,23346363 0,25371514 ! phagocytosis GO:0006909 105 44 0,000 0,23346363 0,25360233 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,23346363 0,25348962 ! double-strand break repair GO:0006302 85 44 0,000 0,23346363 0,25337701 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,23808444 0,25827721 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,23808444 0,25816258 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,23808444 0,25804804 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,23808444 0,25793361 ! biopolymer methylation GO:0043414 91 45 0,000 0,23808444 0,25781928 ! B cell differentiation GO:0030183 124 45 0,000 0,23808444 0,25770504 ! female gamete generation GO:0007292 71 45 0,000 0,23808444 0,25759091 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,23808444 0,25747689 ! polyol metabolic process GO:0019751 77 45 0,000 0,23808444 0,25736296 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,24267752 0,26221194 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,24267752 0,26209602 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,24267752 0,2619802 ! cell growth GO:0016049 90 46 0,000 0,24267752 0,26186448 ! neural tube development GO:0021915 91 47 0,000 0,24724305 0,26667319 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,25178118 0,27144811 ! cellular component disassembly GO:0022411 89 48 0,000 0,25178118 0,27132837 ! endosome transport GO:0016197 127 48 0,000 0,25178118 0,27120874 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,25178118 0,27108921 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,25178118 0,27096979 ! male sex differentiation GO:0046661 93 48 0,000 0,25178118 0,27085047 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,25178118 0,27073126 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,25178118 0,27061215 ! methylation GO:0032259 97 48 0,000 0,25178118 0,27049315 ! response to calcium ion GO:0051592 94 49 0,000 0,25629208 0,27521826 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,25629208 0,27509734 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,25629208 0,27497652 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,25629208 0,27485581 ! regulation of action potential GO:0001508 102 50 0,000 0,26077591 0,2795417 ! regulation of ion transport GO:0043269 86 50 0,000 0,26077591 0,2794191 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,26077591 0,2792966 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,26077591 0,27917421 ! regulation of ossification GO:0030278 123 50 0,000 0,26077591 0,27905192 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,26077591 0,27892975 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,26077591 0,27880768 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,26077591 0,27868571 ! viral infectious cycle GO:0019058 104 51 0,000 0,26523283 0,28332479 ! peptide metabolic process GO:0006518 80 51 0,000 0,26523283 0,28320096 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,26523283 0,28307724 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,26523283 0,28295362 ! positive regulation of binding GO:0051099 88 52 0,000 0,269663 0,28755422 ! Notch signaling pathway GO:0007219 111 52 0,000 0,269663 0,28742876 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,269663 0,28730341 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,269663 0,28717817 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,269663 0,28705303 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,269663 0,28692801 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,269663 0,2868031 ! histone modification GO:0016570 104 52 0,000 0,269663 0,28667829 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,269663 0,28655359 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,269663 0,28642901 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,27406659 0,29097987 ! inner ear development GO:0048839 89 53 0,000 0,27406659 0,29085346 ! chromatin remodeling GO:0006338 122 53 0,000 0,27406659 0,29072717 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,27406659 0,29060099 ! synapse organization GO:0050808 102 53 0,000 0,27406659 0,29047491 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,27844375 0,29498616 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,27844375 0,29485829 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,27844375 0,29473053 ! covalent chromatin modification GO:0016569 115 54 0,000 0,27844375 0,29460289 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,27844375 0,29447536 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,27844375 0,29434793 ! RNA catabolic process GO:0006401 103 55 0,000 0,28279464 0,29881803 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,28279464 0,29868884 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,28279464 0,29855976 ! cell recognition GO:0008037 98 55 0,000 0,28279464 0,2984308 ! cell maturation GO:0048469 107 55 0,000 0,28279464 0,29830194 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,28279464 0,2981732 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,28711941 0,30260255 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,28711941 0,30247207 ! regulation of DNA replication GO:0006275 105 56 0,000 0,28711941 0,30234169 ! RNA elongation GO:0006354 90 56 0,000 0,28711941 0,30221143 ! chloride transport GO:0006821 102 57 0,000 0,29141823 0,30660411 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,29141823 0,30647212 ! muscle fiber development GO:0048747 131 57 0,000 0,29141823 0,30634025 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,29141823 0,30620849 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,29141823 0,30607684 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,29569124 0,31043133 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,29569124 0,31029799 ! aging GO:0007568 112 58 0,000 0,29569124 0,31016475 ! gastrulation GO:0007369 122 58 0,000 0,29569124 0,31003164 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,29569124 0,30989863 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,29569124 0,30976574 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,29569124 0,30963297 ! DNA catabolic process GO:0006308 94 60 0,000 0,30416048 0,31836507 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,30416048 0,31822872 ! adult behavior GO:0030534 104 60 0,000 0,30416048 0,31809249 ! positive regulation of secretion GO:0051047 110 61 0,000 0,30835701 0,32234325 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,30835701 0,32220538 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,30835701 0,32206763 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,30835701 0,32192999 ! regulation of heart contraction GO:0008016 123 61 0,000 0,30835701 0,32179248 ! proton transport GO:0015992 117 61 0,000 0,30835701 0,32165507 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,30835701 0,32151779 ! viral reproductive process GO:0022415 132 62 0,000 0,31252835 0,32572814 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,31252835 0,32558924 ! mesoderm development GO:0007498 128 63 0,000 0,31667465 0,32976819 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,31667465 0,32962768 ! hydrogen transport GO:0006818 121 64 0,000 0,32079606 0,33377545 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,32079606 0,33363336 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,32079606 0,33349139 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,32489272 0,33760651 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,32489272 0,33746297 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,32489272 0,33731956 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,32489272 0,33717626 ! ear development GO:0043583 114 66 0,000 0,32896479 0,34125732 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,32896479 0,34111247 ! gonad development GO:0008406 115 66 0,000 0,32896479 0,34096775 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,32896479 0,34082315 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,33301241 0,34487042 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,33301241 0,34472429 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,33301241 0,34457828 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,33301241 0,3444324 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,33703573 0,34844617 ! detection of external stimulus GO:0009581 102 68 0,000 0,33703573 0,34829877 ! viral reproduction GO:0016032 142 68 0,000 0,33703573 0,3481515 ! regulation of lipase activity GO:0060191 137 68 0,000 0,33703573 0,34800435 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,3410349 0,3519849 ! lung development GO:0030324 165 69 0,000 0,3410349 0,35183626 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,3410349 0,35168774 ! single fertilization GO:0007338 83 69 0,000 0,3410349 0,35153935 ! cell redox homeostasis GO:0045454 114 70 0,000 0,34501005 0,35548695 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,34896133 0,35940663 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,34896133 0,35925518 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,34896133 0,35910385 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,34896133 0,35895265 ! appendage morphogenesis GO:0035107 150 72 0,000 0,35288889 0,36283988 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 0,000 0,35288889 0,36268724 ! B cell activation GO:0042113 179 72 0,000 0,35288889 0,36253472 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,35288889 0,36238233 ! appendage development GO:0048736 151 73 0,000 0,35679287 0,36623738 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,35679287 0,36608357 ! amino acid transport GO:0006865 148 74 0,000 0,3606734 0,36990979 ! respiratory system development GO:0060541 175 74 0,000 0,3606734 0,36975456 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,36453063 0,37355215 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,36453063 0,37339552 ! reproductive structure development GO:0048608 131 75 0,000 0,36453063 0,37323903 ! axon guidance GO:0007411 162 75 0,000 0,36453063 0,37308266 ! rhythmic process GO:0048511 142 75 0,000 0,36453063 0,37292643 ! learning or memory GO:0007611 161 76 0,000 0,36836469 0,37669106 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,36836469 0,37653345 ! regulation of blood pressure GO:0008217 134 76 0,000 0,36836469 0,37637597 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,36836469 0,37621862 ! amine catabolic process GO:0009310 136 77 0,000 0,37217573 0,37995207 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,37217573 0,37979336 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,37596388 0,38349886 ! antigen processing and presentation GO:0019882 117 78 0,000 0,37596388 0,3833388 ! fertilization GO:0009566 99 78 0,000 0,37596388 0,38317888 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,37972928 0,38685515 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,37972928 0,38669389 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,38347207 0,39034261 ! muscle cell differentiation GO:0042692 178 81 0,000 0,38719238 0,39396542 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,38719238 0,39380141 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,39456609 0,40113398 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,39456609 0,40096712 ! inorganic anion transport GO:0015698 156 83 0,000 0,39456609 0,4008004 ! response to metal ion GO:0010038 158 84 0,000 0,39821976 0,40434367 ! response to nutrient GO:0007584 135 84 0,000 0,39821976 0,40417569 ! digestion GO:0007586 130 84 0,000 0,39821976 0,40400784 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,40185149 0,40752311 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,40185149 0,40735402 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,40185149 0,40718506 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,4054614 0,41067255 ! regulation of lyase activity GO:0051339 169 86 0,000 0,4054614 0,41050236 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,40904962 0,41396364 ! nucleosome assembly GO:0006334 126 87 0,000 0,40904962 0,41379223 ! cellular respiration GO:0045333 143 88 0,000 0,41261629 0,41722748 ! amine biosynthetic process GO:0009309 146 88 0,000 0,41261629 0,41705486 ! sensory perception of smell GO:0007608 117 88 0,000 0,41261629 0,41688238 ! chromatin assembly GO:0031497 128 88 0,000 0,41261629 0,41671004 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,41616153 0,42011679 ! cellular defense response GO:0006968 123 89 0,000 0,41616153 0,41994326 ! regulation of neurological system process GO:0031644 175 89 0,000 0,41616153 0,41976987 ! response to inorganic substance GO:0010035 173 90 0,000 0,41968548 0,42314966 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,41968548 0,42297509 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,42318825 0,42632944 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,42318825 0,42615371 ! bone development GO:0060348 206 92 0,000 0,42666998 0,4294828 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,42666998 0,42930591 ! amine transport GO:0015837 181 93 0,000 0,43013079 0,43260993 ! vitamin metabolic process GO:0006766 153 93 0,000 0,43013079 0,4324319 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,4335708 0,43571101 ! sterol metabolic process GO:0016125 166 94 0,000 0,4335708 0,43553186 ! nucleosome organization GO:0034728 143 95 0,000 0,43699015 0,43878625 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,43699015 0,43860597 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,43699015 0,43842585 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,43699015 0,43824587 ! sex differentiation GO:0007548 171 96 0,000 0,44038895 0,44147321 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,44376733 0,44467744 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,44376733 0,44449512 ! transcription initiation GO:0006352 171 97 0,000 0,44376733 0,44431295 ! leukocyte differentiation GO:0002521 232 98 0,000 0,44712541 0,44749175 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,44712541 0,44730851 ! hormone metabolic process GO:0042445 171 100 0,000 0,45378115 0,45378115