pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1300-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of epidermis development GO:0045684 11 7 3,000 1,474E-07 3,39E-04 ! CTP metabolic process GO:0046036 9 9 3,000 5,239E-07 6,025E-04 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of epithelial cell proliferation GO:0050678 71 39 5,000 7,043E-07 5,4E-04 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 3,000 8,677E-07 4,989E-04 ! focal adhesion formation GO:0048041 24 11 3,000 1,355E-06 6,232E-04 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 3,000 2,019E-06 7,741E-04 ! regulation of epidermis development GO:0045682 17 12 3,000 2,019E-06 6,635E-04 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 3,000 4,032E-06 1,159E-03 ! epidermis morphogenesis GO:0048730 29 14 3,000 4,032E-06 1,03E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 2,000 5,296E-06 1,218E-03 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 3,000 5,463E-06 1,142E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 3,000 7,238E-06 1,387E-03 ! G1 phase GO:0051318 27 16 3,000 7,238E-06 1,281E-03 ! cell-substrate junction assembly GO:0007044 39 17 3,000 9,405E-06 1,545E-03 ! regulation of epidermal cell differentiation GO:0045604 7 6 2,000 1,053E-05 1,614E-03 ! gliogenesis GO:0042063 71 38 4,000 1,379E-05 1,982E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 3,000 1,512E-05 2,046E-03 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 3,000 1,512E-05 1,932E-03 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 3,000 2,306E-05 2,791E-03 ! UTP metabolic process GO:0046051 8 8 2,000 2,912E-05 3,349E-03 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! regulation of ossification GO:0030278 71 46 4,000 3,573E-05 3,913E-03 ! GTP metabolic process GO:0046039 9 9 2,000 4,342E-05 4,54E-03 ! regulation of chromosome organization GO:0033044 35 25 3,000 4,751E-05 4,751E-03 ! positive regulation of cell migration GO:0030335 92 51 4,000 5,925E-05 5,678E-03 ! hair follicle morphogenesis GO:0031069 17 10 2,000 6,166E-05 5,673E-03 ! regulation of bone remodeling GO:0046850 90 53 4,000 7,144E-05 6,32E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 5,000 7,406E-05 6,309E-03 ! cell junction assembly GO:0034329 56 28 3,000 7,544E-05 6,197E-03 ! regulation of tissue remodeling GO:0034103 91 54 4,000 7,822E-05 6,204E-03 ! interphase GO:0051325 159 88 5,000 8,423E-05 6,458E-03 ! digestive tract morphogenesis GO:0048546 15 11 2,000 8,428E-05 6,253E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of cell motion GO:0051272 99 56 4,000 9,325E-05 6,702E-03 ! hindbrain development GO:0030902 45 30 3,000 9,97E-05 6,949E-03 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 1,015E-04 6,869E-03 ! steroid hormone receptor signaling pathway GO:0030518 96 58 4,000 1,104E-04 7,255E-03 ! gland morphogenesis GO:0022612 23 12 2,000 1,117E-04 7,136E-03 ! cell junction organization GO:0034330 63 33 3,000 1,461E-04 9,08E-03 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 3,000 1,461E-04 8,841E-03 ! negative regulation of cell growth GO:0030308 106 62 4,000 1,519E-04 8,957E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 4,000 1,639E-04 9,424E-03 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 1,645E-04 9,228E-03 ! negative regulation of cell size GO:0045792 108 64 4,000 1,766E-04 9,672E-03 ! G1 phase of mitotic cell cycle GO:0000080 23 14 2,000 1,826E-04 9,767E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,826E-04 9,545E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 2,269E-04 0,01159665 ! ribonucleoside metabolic process GO:0009119 48 37 3,000 2,299E-04 0,01149266 ! mitochondrion organization GO:0007005 104 73 4,000 3,281E-04 0,01605411 ! peptidyl-serine modification GO:0018209 27 17 2,000 3,35E-04 0,0160543 ! negative regulation of growth GO:0045926 123 75 4,000 3,721E-04 0,01746461 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 3,997E-04 0,01838402 ! estrogen receptor signaling pathway GO:0030520 30 18 2,000 3,997E-04 0,01802354 ! gut development GO:0048565 26 18 2,000 3,997E-04 0,01767694 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 4,135E-04 0,01794385 ! response to insulin stimulus GO:0032868 63 43 3,000 4,135E-04 0,01761156 ! response to alkaloid GO:0043279 32 19 2,000 4,718E-04 0,01972781 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 4,718E-04 0,01937552 ! positive regulation of cell cycle GO:0045787 77 45 3,000 4,929E-04 0,01989043 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 6,398E-04 0,02537109 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 6,398E-04 0,02494107 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 6,538E-04 0,02506241 ! positive regulation of histone modification GO:0031058 5 5 1,000 6,538E-04 0,02465155 ! glial cell fate commitment GO:0021781 12 5 1,000 6,538E-04 0,02425394 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 1,000 6,538E-04 0,02386896 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 6,538E-04 0,02349601 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 6,538E-04 0,02313453 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 1,000 6,538E-04 0,02278401 ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 6,538E-04 0,02244395 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 1,000 6,538E-04 0,02211389 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 1,000 6,538E-04 0,0217934 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 6,538E-04 0,02148206 ! monocyte differentiation GO:0030224 8 5 1,000 6,538E-04 0,0211795 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 1,000 6,538E-04 0,02088534 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! positive regulation of organ growth GO:0046622 6 5 1,000 6,538E-04 0,02059924 ! enteric nervous system development GO:0048484 8 5 1,000 6,538E-04 0,02032087 ! muscle cell proliferation GO:0033002 8 5 1,000 6,538E-04 0,02004993 ! regulation of hair follicle development GO:0051797 9 5 1,000 6,538E-04 0,01978611 GO:0042634|regulation of hair cycle, ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 6,538E-04 0,01952915 ! glial cell migration GO:0008347 10 5 1,000 6,538E-04 0,01927877 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 6,538E-04 0,01903474 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 6,538E-04 0,01879681 ! receptor biosynthetic process GO:0032800 6 5 1,000 6,538E-04 0,01856475 ! cell cycle arrest GO:0007050 150 86 4,000 6,988E-04 0,01959946 ! molting cycle process GO:0022404 40 22 2,000 7,364E-04 0,02040603 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 7,364E-04 0,0201631 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of growth GO:0045927 67 50 3,000 7,382E-04 0,01997557 ! positive regulation of organelle organization GO:0010638 82 51 3,000 7,96E-04 0,02128871 ! embryonic pattern specification GO:0009880 31 23 2,000 8,418E-04 0,02225443 ! positive regulation of cell adhesion GO:0045785 37 23 2,000 8,418E-04 0,02200154 ! cell fate commitment GO:0045165 141 92 4,000 9,489E-04 0,02452117 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 9,563E-04 0,02443923 ! fat cell differentiation GO:0045444 37 24 2,000 9,563E-04 0,02417067 ! regulation of osteoblast differentiation GO:0045667 37 24 2,000 9,563E-04 0,02390794 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 9,754E-04 0,02412376 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 1,000 9,754E-04 0,02386713 ! pigment granule organization GO:0048753 11 6 1,000 9,754E-04 0,02361589 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 9,754E-04 0,0233699 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! ER overload response GO:0006983 7 6 1,000 9,754E-04 0,02312897 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 1,000 9,754E-04 0,02289296 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 9,754E-04 0,02266172 ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 9,754E-04 0,0224351 ! positive regulation of cytokine production during immune response GO:0002720 8 6 1,000 9,754E-04 0,02221297 ! response to copper ion GO:0046688 9 6 1,000 9,754E-04 0,0219952 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 9,754E-04 0,02178165 ! negative regulation of T cell differentiation GO:0045581 7 6 1,000 9,754E-04 0,02157221 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 9,754E-04 0,02136676 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 9,754E-04 0,02116519 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 1,000 9,754E-04 0,02096738 ! midbrain development GO:0030901 6 6 1,000 9,754E-04 0,02077324 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 1,000 9,754E-04 0,02058266 GO:0045625|regulation of T-helper 1 cell differentiation, ! blastocyst growth GO:0001832 15 6 1,000 9,754E-04 0,02039555 ! regulation of mitosis GO:0007088 84 54 3,000 9,885E-04 0,02048172 GO:0051783|regulation of nuclear division, ! nucleoside metabolic process GO:0009116 69 55 3,000 1,059E-03 0,02175324 ! positive regulation of nuclear division GO:0051785 39 25 2,000 1,08E-03 0,02198731 GO:0045840|positive regulation of mitosis, ! cellular copper ion homeostasis GO:0006878 9 7 1,000 1,358E-03 0,02740409 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,358E-03 0,02716579 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 1,358E-03 0,02693161 ! regulation of gluconeogenesis GO:0006111 7 7 1,000 1,358E-03 0,02670142 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,358E-03 0,02647514 ! lipoprotein transport GO:0042953 9 7 1,000 1,358E-03 0,02625266 ! T-helper 1 type immune response GO:0042088 11 7 1,000 1,358E-03 0,02603389 ! regulation of pigmentation during development GO:0048070 15 7 1,000 1,358E-03 0,02581873 ! organ growth GO:0035265 11 7 1,000 1,358E-03 0,0256071 ! behavioral fear response GO:0001662 13 7 1,000 1,358E-03 0,02539891 GO:0002209|behavioral defense response, ! response to UV-B GO:0010224 11 7 1,000 1,358E-03 0,02519408 ! B cell lineage commitment GO:0002326 17 7 1,000 1,358E-03 0,02499253 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 1,000 1,358E-03 0,02479418 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 1,000 1,358E-03 0,02459895 ! regulation of fat cell differentiation GO:0045598 9 7 1,000 1,358E-03 0,02440677 ! T cell lineage commitment GO:0002360 12 7 1,000 1,358E-03 0,02421757 ! peptidyl-threonine modification GO:0018210 18 7 1,000 1,358E-03 0,02403128 ! dopamine biosynthetic process GO:0042416 15 7 1,000 1,358E-03 0,02384783 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 1,358E-03 0,02366717 ! myeloid cell differentiation GO:0030099 85 59 3,000 1,378E-03 0,0238366 ! Ras protein signal transduction GO:0007265 162 100 4,000 1,379E-03 0,02366845 ! regulation of homeostatic process GO:0032844 105 60 3,000 1,468E-03 0,02500281 ! cell-matrix adhesion GO:0007160 114 61 3,000 1,561E-03 0,02639385 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 3,000 1,561E-03 0,02620119 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 3,000 1,658E-03 0,02763064 ! Golgi to endosome transport GO:0006895 16 8 1,000 1,801E-03 0,02980642 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,801E-03 0,02959352 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,801E-03 0,02938364 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,801E-03 0,02917671 ! pseudouridine synthesis GO:0001522 9 8 1,000 1,801E-03 0,02897268 ! melanin metabolic process GO:0006582 12 8 1,000 1,801E-03 0,02877148 ! retrograde transport, endosome to Golgi GO:0042147 12 8 1,000 1,801E-03 0,02857305 ! copper ion homeostasis GO:0055070 10 8 1,000 1,801E-03 0,02837735 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,801E-03 0,02818431 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 1,801E-03 0,02799387 ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 1,000 1,801E-03 0,02780599 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! regulation of T-helper 1 type immune response GO:0002825 9 8 1,000 1,801E-03 0,02762062 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,801E-03 0,0274377 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,801E-03 0,02725719 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 3,000 1,974E-03 0,02968094 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 3,000 1,974E-03 0,02948821 ! protein oligomerization GO:0051259 100 65 3,000 1,974E-03 0,02929796 ! glial cell differentiation GO:0010001 55 31 2,000 2,037E-03 0,03003088 ! leukocyte chemotaxis GO:0030595 43 31 2,000 2,037E-03 0,0298396 GO:0060326|cell chemotaxis, ! cell-substrate adhesion GO:0031589 121 66 3,000 2,089E-03 0,03040407 ! regulation of protein stability GO:0031647 48 32 2,000 2,234E-03 0,03231897 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 1,000 2,304E-03 0,03311436 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 2,304E-03 0,03290868 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 1,000 2,304E-03 0,03270554 GO:0010469|regulation of receptor activity, ! SMAD protein nuclear translocation GO:0007184 15 9 1,000 2,304E-03 0,03250489 ! regulation of histone modification GO:0031056 11 9 1,000 2,304E-03 0,03230669 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 1,000 2,304E-03 0,03211089 ! T cell selection GO:0045058 18 9 1,000 2,304E-03 0,03191746 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 2,304E-03 0,03172633 ! negative regulation of lymphocyte differentiation GO:0045620 11 9 1,000 2,304E-03 0,03153749 ! oocyte differentiation GO:0009994 12 9 1,000 2,304E-03 0,03135087 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 1,000 2,304E-03 0,03116646 ! spleen development GO:0048536 15 9 1,000 2,304E-03 0,0309842 ! regulation of RNA splicing GO:0043484 14 9 1,000 2,304E-03 0,03080406 ! response to nicotine GO:0035094 16 9 1,000 2,304E-03 0,030626 ! carbohydrate homeostasis GO:0033500 39 33 2,000 2,443E-03 0,03229306 GO:0042593|glucose homeostasis, ! positive regulation of cell development GO:0010720 54 33 2,000 2,443E-03 0,03210853 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 2,443E-03 0,03192609 ! positive regulation of ligase activity GO:0051351 99 69 3,000 2,458E-03 0,03194633 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 3,000 2,729E-03 0,03525762 ! regulation of phosphatase activity GO:0010921 21 10 1,000 2,864E-03 0,0368012 ! positive regulation of heart contraction GO:0045823 14 10 1,000 2,864E-03 0,03659675 ! positive regulation of lipid metabolic process GO:0045834 12 10 1,000 2,864E-03 0,03639456 ! B cell proliferation GO:0042100 14 10 1,000 2,864E-03 0,03619459 ! fear response GO:0042596 16 10 1,000 2,864E-03 0,03599681 ! negative regulation of ossification GO:0030279 19 10 1,000 2,864E-03 0,03580117 ! alpha-beta T cell activation GO:0046631 16 10 1,000 2,864E-03 0,03560765 ! regulation of organ growth GO:0046620 11 10 1,000 2,864E-03 0,03541621 ! embryonic axis specification GO:0000578 12 10 1,000 2,864E-03 0,03522682 ! mRNA polyadenylation GO:0006378 18 10 1,000 2,864E-03 0,03503944 ! salivary gland development GO:0007431 22 10 1,000 2,864E-03 0,03485405 ! embryonic gut development GO:0048566 11 10 1,000 2,864E-03 0,03467061 ! T cell receptor signaling pathway GO:0050852 18 10 1,000 2,864E-03 0,03448909 ! glycogen metabolic process GO:0005977 48 35 2,000 2,896E-03 0,03469107 ! protein homooligomerization GO:0051260 52 35 2,000 2,896E-03 0,03451132 ! glucan metabolic process GO:0044042 49 36 2,000 3,14E-03 0,03723229 GO:0006073|cellular glucan metabolic process, ! cellular response to hormone stimulus GO:0032870 109 74 3,000 3,171E-03 0,03740126 ! regulation of ligase activity GO:0051340 114 75 3,000 3,329E-03 0,03906082 ! RNA polyadenylation GO:0043631 19 11 1,000 3,482E-03 0,04065081 ! detection of mechanical stimulus GO:0050982 15 11 1,000 3,482E-03 0,0404455 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 1,000 3,482E-03 0,04024226 ! oligodendrocyte differentiation GO:0048709 14 11 1,000 3,482E-03 0,04004105 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 3,482E-03 0,03984184 ! temperature homeostasis GO:0001659 16 11 1,000 3,482E-03 0,0396446 ! protein homotetramerization GO:0051289 18 11 1,000 3,482E-03 0,03944931 ! positive regulation of T cell mediated immunity GO:0002711 18 11 1,000 3,482E-03 0,03925593 ! chromatin silencing GO:0006342 19 11 1,000 3,482E-03 0,03906444 ! T cell homeostasis GO:0043029 20 11 1,000 3,482E-03 0,0388748 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 1,000 3,482E-03 0,038687 ! mRNA 3'-end processing GO:0031124 19 11 1,000 3,482E-03 0,03850101 ! mesenchymal cell development GO:0014031 64 38 2,000 3,667E-03 0,04035011 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 2,000 3,667E-03 0,04015796 ! developmental growth GO:0048589 62 39 2,000 3,949E-03 0,04304152 ! cell growth GO:0016049 61 39 2,000 3,949E-03 0,0428385 ! positive regulation of cell growth GO:0030307 16 12 1,000 4,156E-03 0,04487544 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 4,156E-03 0,04466575 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 4,156E-03 0,044458 ! regulation of interleukin-12 production GO:0032655 16 12 1,000 4,156E-03 0,04425217 ! autonomic nervous system development GO:0048483 23 12 1,000 4,156E-03 0,04404825 ! response to gamma radiation GO:0010332 20 12 1,000 4,156E-03 0,04384619 ! regulation of fatty acid oxidation GO:0046320 18 12 1,000 4,156E-03 0,04364598 ! RNA 3'-end processing GO:0031123 20 12 1,000 4,156E-03 0,04344759 ! microspike assembly GO:0030035 23 12 1,000 4,156E-03 0,04325099 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 3,000 4,198E-03 0,04348879 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 131 80 3,000 4,198E-03 0,04329377 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 4,243E-03 0,04357109 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 4,243E-03 0,04337744 ! regulation of cell cycle process GO:0010564 122 81 3,000 4,388E-03 0,04465746 ! energy reserve metabolic process GO:0006112 59 41 2,000 4,551E-03 0,04611475 ! endosome transport GO:0016197 71 41 2,000 4,551E-03 0,04591249 ! regulation of cell adhesion GO:0030155 159 83 3,000 4,786E-03 0,04807231 ! mitochondrial transport GO:0006839 60 42 2,000 4,872E-03 0,04872396 ! pteridine and derivative biosynthetic process GO:0042559 15 13 1,000 4,885E-03 0,04864075 ! endocrine pancreas development GO:0031018 19 13 1,000 4,885E-03 0,04843109 ! exocrine system development GO:0035272 27 13 1,000 4,885E-03 0,04822323 ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 4,885E-03 0,04801715 ! regulation of cytokine production during immune response GO:0002718 18 13 1,000 4,885E-03 0,04781282 ! cellular pigmentation GO:0033059 24 13 1,000 4,885E-03 0,04761022 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 4,885E-03 0,04740934 ! lymphocyte homeostasis GO:0002260 24 13 1,000 4,885E-03 0,04721014 ! leukocyte migration GO:0050900 60 43 2,000 5,207E-03 0,05010741 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 2,000 5,207E-03 0,04989863 ! epithelial tube morphogenesis GO:0060562 65 43 2,000 5,207E-03 0,04969158 ! transcription initiation GO:0006352 118 85 3,000 5,208E-03 0,04949929 ! regulation of protein localization GO:0032880 132 85 3,000 5,208E-03 0,04929559 ! glycolysis GO:0006096 53 44 2,000 5,555E-03 0,05236015 ! skeletal muscle tissue development GO:0007519 123 87 3,000 5,654E-03 0,05308081 GO:0060538|skeletal muscle organ development, ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 5,669E-03 0,05300278 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 5,669E-03 0,05278819 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 1,000 5,669E-03 0,05257534 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 5,669E-03 0,05236419 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 27 14 1,000 5,669E-03 0,05215473 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 5,669E-03 0,05194694 ! regulation of T-helper 2 type immune response GO:0002828 21 14 1,000 5,669E-03 0,05174081 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 5,669E-03 0,0515363 ! muscle maintenance GO:0046716 19 14 1,000 5,669E-03 0,0513334 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 1,000 5,669E-03 0,05113209 ! catecholamine biosynthetic process GO:0042423 23 14 1,000 5,669E-03 0,05093236 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 5,669E-03 0,05073418 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 3,000 5,887E-03 0,05247713 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 3,000 6,125E-03 0,0543932 ! regulation of adaptive immune response GO:0002819 72 46 2,000 6,292E-03 0,05565665 ! leukocyte differentiation GO:0002521 143 90 3,000 6,37E-03 0,0561348 ! positive regulation of cell size GO:0045793 20 15 1,000 6,506E-03 0,05711584 ! metencephalon development GO:0022037 19 15 1,000 6,506E-03 0,05689867 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 6,506E-03 0,05668314 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 6,506E-03 0,05646924 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 1,000 6,506E-03 0,05625695 ! adult walking behavior GO:0007628 25 15 1,000 6,506E-03 0,05604625 ! myoblast differentiation GO:0045445 27 15 1,000 6,506E-03 0,05583713 ! regulation of survival gene product expression GO:0045884 20 15 1,000 6,506E-03 0,05562955 ! regulation of T cell mediated immunity GO:0002709 26 15 1,000 6,506E-03 0,05542352 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 6,506E-03 0,055219 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 6,506E-03 0,05501599 ! regulation of T-helper cell differentiation GO:0045622 23 15 1,000 6,506E-03 0,05481447 ! dopamine metabolic process GO:0042417 30 15 1,000 6,506E-03 0,05461442 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 6,506E-03 0,05441582 ! defense response to virus GO:0051607 27 15 1,000 6,506E-03 0,05421866 ! negative regulation of immune system process GO:0002683 73 47 2,000 6,681E-03 0,0554729 ! regulation of neuron apoptosis GO:0043523 77 47 2,000 6,681E-03 0,05527336 ! positive regulation of immune response GO:0050778 121 92 3,000 6,879E-03 0,05671088 ! cellular polysaccharide metabolic process GO:0044264 63 48 2,000 7,084E-03 0,05819121 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 7,396E-03 0,06053704 ! protein polyubiquitination GO:0000209 26 16 1,000 7,396E-03 0,06032237 ! fructose metabolic process GO:0006000 20 16 1,000 7,396E-03 0,06010922 ! regulation of protein binding GO:0043393 27 16 1,000 7,396E-03 0,05989757 ! regulation of dephosphorylation GO:0035303 33 16 1,000 7,396E-03 0,0596874 ! negative regulation of immune response GO:0050777 28 16 1,000 7,396E-03 0,0594787 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 1,000 7,396E-03 0,05927146 ! oogenesis GO:0048477 23 16 1,000 7,396E-03 0,05906566 ! neutrophil chemotaxis GO:0030593 21 16 1,000 7,396E-03 0,05886128 ! aromatic compound biosynthetic process GO:0019438 18 16 1,000 7,396E-03 0,05865831 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 1,000 7,396E-03 0,05845673 ! response to oxidative stress GO:0006979 141 94 3,000 7,415E-03 0,05840358 ! ear development GO:0043583 72 50 2,000 7,933E-03 0,06227494 ! skeletal muscle fiber development GO:0048741 73 50 2,000 7,933E-03 0,06206312 ! regulation of multicellular organism growth GO:0040014 65 50 2,000 7,933E-03 0,06185274 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 3,000 8,268E-03 0,06424667 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 1,000 8,338E-03 0,06456661 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 8,338E-03 0,06434994 ! regulation of viral genome replication GO:0045069 24 17 1,000 8,338E-03 0,06413473 ! actin filament bundle formation GO:0051017 26 17 1,000 8,338E-03 0,06392094 ! neuromuscular junction development GO:0007528 23 17 1,000 8,338E-03 0,06370858 ! long-chain fatty acid transport GO:0015909 24 17 1,000 8,338E-03 0,06349763 ! regulation of immunoglobulin production GO:0002637 25 17 1,000 8,338E-03 0,06328806 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 8,338E-03 0,06307988 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 8,379E-03 0,06318866 ! muscle fiber development GO:0048747 74 51 2,000 8,379E-03 0,06298216 ! extracellular structure organization GO:0043062 156 99 3,000 8,872E-03 0,06646522 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 9,33E-03 0,06967019 ! axis specification GO:0009798 26 18 1,000 9,33E-03 0,06944472 ! pancreas development GO:0031016 26 18 1,000 9,33E-03 0,0692207 ! glutamine metabolic process GO:0006541 23 18 1,000 9,33E-03 0,06899813 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 9,33E-03 0,06877698 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 1,000 9,33E-03 0,06855725 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 1,000 9,33E-03 0,06833891 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 9,33E-03 0,06812196 ! negative regulation of T cell activation GO:0050868 25 18 1,000 9,33E-03 0,06790639 ! glucose catabolic process GO:0006007 66 54 2,000 9,805E-03 0,07113933 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 0,01037186 0,07501663 ! positive regulation of ossification GO:0045778 30 19 1,000 0,01037186 0,07478147 ! pteridine and derivative metabolic process GO:0042558 23 19 1,000 0,01037186 0,07454777 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 0,01037186 0,07431554 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regeneration GO:0031099 32 19 1,000 0,01037186 0,07408474 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 0,01037186 0,07385538 ! apoptotic nuclear changes GO:0030262 24 19 1,000 0,01037186 0,07362743 ! response to starvation GO:0042594 30 19 1,000 0,01037186 0,07340088 ! renal system process GO:0003014 35 19 1,000 0,01037186 0,07317573 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 1,000 0,01037186 0,07295195 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 0,01037186 0,07272954 ! regulation of interleukin-6 production GO:0032675 22 19 1,000 0,01037186 0,07250847 ! regulation of interleukin-2 production GO:0032663 31 19 1,000 0,01037186 0,07228875 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 0,01037186 0,07207036 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 0,01037186 0,07185328 ! embryonic organ morphogenesis GO:0048562 23 19 1,000 0,01037186 0,0716375 ! protein stabilization GO:0050821 26 19 1,000 0,01037186 0,07142302 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 0,01082879 0,07434694 ! hindlimb morphogenesis GO:0035137 32 20 1,000 0,01146299 0,07846693 ! response to ethanol GO:0045471 37 20 1,000 0,01146299 0,07823409 ! multicellular organismal response to stress GO:0033555 32 20 1,000 0,01146299 0,07800263 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 0,01146299 0,07777253 ! collagen fibril organization GO:0030199 45 20 1,000 0,01146299 0,07754379 ! positive regulation of osteoblast differentiation GO:0045669 33 20 1,000 0,01146299 0,07731639 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 2,000 0,01247668 0,08390752 ! actin filament organization GO:0007015 95 59 2,000 0,01247668 0,08366289 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 0,01260228 0,08425943 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 0,01260228 0,0840152 ! positive regulation of bone remodeling GO:0046852 33 21 1,000 0,01260228 0,08377238 GO:0034105|positive regulation of tissue remodeling, ! ovarian follicle development GO:0001541 30 21 1,000 0,01260228 0,08353096 ! cell aging GO:0007569 32 21 1,000 0,01260228 0,08329093 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 0,01260228 0,08305227 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 0,01260228 0,08281498 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 0,01260228 0,08257904 ! fatty acid transport GO:0015908 30 21 1,000 0,01260228 0,08234444 ! positive regulation of adaptive immune response GO:0002821 31 21 1,000 0,01260228 0,08211117 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 0,01260228 0,08187922 ! response to cytokine stimulus GO:0034097 47 21 1,000 0,01260228 0,08164857 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 2,000 0,01305611 0,08435128 ! regulation of heart contraction GO:0008016 91 60 2,000 0,01305611 0,084115 ! homeostasis of number of cells GO:0048872 84 61 2,000 0,0136507 0,08770004 ! extracellular matrix organization GO:0030198 103 61 2,000 0,0136507 0,08745575 ! negative regulation of ligase activity GO:0051352 91 61 2,000 0,0136507 0,08721282 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein import into nucleus, translocation GO:0000060 36 22 1,000 0,01378887 0,08785151 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01378887 0,08760883 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 0,01378887 0,08736748 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 1,000 0,01378887 0,08712746 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! ureteric bud development GO:0001657 32 22 1,000 0,01378887 0,08688876 ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01378887 0,08665136 ! blastocyst development GO:0001824 37 22 1,000 0,01378887 0,08641525 ! neural tube closure GO:0001843 33 22 1,000 0,01378887 0,08618043 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 1,000 0,01378887 0,08594687 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01502192 0,09337952 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 0,01502192 0,09312782 ! lymphocyte proliferation GO:0046651 36 23 1,000 0,01502192 0,09287748 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 0,01502192 0,09262848 ! liver development GO:0001889 40 23 1,000 0,01502192 0,09238081 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 0,01502192 0,09213446 ! osteoblast differentiation GO:0001649 40 23 1,000 0,01502192 0,09188942 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,01502192 0,09164568 ! cell fate determination GO:0001709 45 23 1,000 0,01502192 0,09140323 ! hexose catabolic process GO:0019320 82 64 2,000 0,01552595 0,09422082 ! adaptive immune response GO:0002250 94 64 2,000 0,01552595 0,09397287 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of T cell activation GO:0050870 94 65 2,000 0,01618167 0,09768463 ! activation of immune response GO:0002253 83 65 2,000 0,01618167 0,09742891 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01630061 0,0978888 ! receptor metabolic process GO:0043112 37 24 1,000 0,01630061 0,09763388 ! response to toxin GO:0009636 38 24 1,000 0,01630061 0,09738029 ! primary neural tube formation GO:0014020 35 24 1,000 0,01630061 0,09712801 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,01630061 0,09687703 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 1,000 0,01630061 0,09662735 GO:0002708|positive regulation of lymphocyte mediated immunity, ! neurotransmitter secretion GO:0007269 32 24 1,000 0,01630061 0,09637895 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 0,01762412 0,10393714 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 0,01762412 0,10367132 ! male gonad development GO:0008584 33 25 1,000 0,01762412 0,10340685 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01762412 0,10314373 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 0,01762412 0,10288194 ! leukocyte proliferation GO:0070661 39 25 1,000 0,01762412 0,10262148 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 0,01762412 0,10236234 ! response to drug GO:0042493 108 69 2,000 0,01895861 0,10983579 ! activation of protein kinase activity GO:0032147 102 69 2,000 0,01895861 0,10955982 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 1,000 0,01899165 0,10947565 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,01899165 0,10920196 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01899165 0,10892963 ! post-embryonic development GO:0009791 42 26 1,000 0,01899165 0,10865867 ! response to metal ion GO:0010038 103 70 2,000 0,01969148 0,11238316 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 2,000 0,01969148 0,11210498 ! humoral immune response GO:0006959 86 70 2,000 0,01969148 0,11182818 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 2,000 0,01969148 0,11155274 ! catechol metabolic process GO:0009712 43 27 1,000 0,02040238 0,115296 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 47 27 1,000 0,02040238 0,11501341 ! response to ionizing radiation GO:0010212 47 27 1,000 0,02040238 0,1147322 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 0,02040238 0,11445237 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 0,02040238 0,1141739 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,02040238 0,11389678 ! gene silencing GO:0016458 41 27 1,000 0,02040238 0,113621 ! muscle cell differentiation GO:0042692 104 71 2,000 0,02043985 0,1135547 ! monosaccharide catabolic process GO:0046365 91 71 2,000 0,02043985 0,11328107 ! response to hypoxia GO:0001666 132 72 2,000 0,02120371 0,11723203 ! phenol metabolic process GO:0018958 44 28 1,000 0,02185554 0,12054613 ! complement activation, classical pathway GO:0006958 36 28 1,000 0,02185554 0,12025774 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,02185554 0,11997073 ! immune response-activating signal transduction GO:0002757 38 28 1,000 0,02185554 0,11968509 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 1,000 0,02185554 0,1194008 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,02185554 0,11911786 ! mesoderm formation GO:0001707 46 28 1,000 0,02185554 0,11883626 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,02185554 0,11855598 ! BMP signaling pathway GO:0030509 40 28 1,000 0,02185554 0,11827703 ! myeloid leukocyte activation GO:0002274 39 28 1,000 0,02185554 0,11799938 ! neural tube formation GO:0001841 41 28 1,000 0,02185554 0,11772304 ! placenta development GO:0001890 37 28 1,000 0,02185554 0,11744798 ! tube morphogenesis GO:0035239 118 73 2,000 0,02198307 0,11785797 ! response to oxygen levels GO:0070482 137 74 2,000 0,02277795 0,12183555 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 0,02277795 0,12155287 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,02335034 0,12431896 ! ovulation cycle process GO:0022602 41 29 1,000 0,02335034 0,12403185 ! formation of primary germ layer GO:0001704 48 29 1,000 0,02335034 0,12374606 ! tissue homeostasis GO:0001894 42 29 1,000 0,02335034 0,12346159 GO:0048871|multicellular organismal homeostasis, ! response to inorganic substance GO:0010035 115 75 2,000 0,02358834 0,12443389 ! response to nutrient GO:0007584 104 75 2,000 0,02358834 0,12414915 ! regulation of protein transport GO:0051223 114 76 2,000 0,02441423 0,12820258 GO:0070201|regulation of establishment of protein localization, ! spindle organization GO:0007051 37 30 1,000 0,02488603 0,13038238 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 1,000 0,02488603 0,13008605 ! ceramide metabolic process GO:0006672 43 30 1,000 0,02488603 0,12979107 ! ovulation cycle GO:0042698 43 30 1,000 0,02488603 0,12949743 ! adult locomotory behavior GO:0008344 47 30 1,000 0,02488603 0,12920511 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 0,02488603 0,12891411 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,02488603 0,12862441 ! response to heat GO:0009408 41 30 1,000 0,02488603 0,12833602 ! positive regulation of immune effector process GO:0002699 40 30 1,000 0,02488603 0,12804891 ! gland development GO:0048732 148 77 2,000 0,02525562 0,12966057 ! odontogenesis GO:0042476 50 31 1,000 0,02646183 0,13555058 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,02646183 0,13524936 ! mesoderm morphogenesis GO:0048332 49 31 1,000 0,02646183 0,13494947 ! metanephros development GO:0001656 58 31 1,000 0,02646183 0,13465091 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02646183 0,13435367 ! biogenic amine biosynthetic process GO:0042401 44 31 1,000 0,02646183 0,13405773 ! RNA modification GO:0009451 40 31 1,000 0,02646183 0,1337631 ! alcohol catabolic process GO:0046164 104 80 2,000 0,02787268 0,14058586 ! regulation of muscle development GO:0048634 48 32 1,000 0,028077 0,14130659 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,028077 0,14099806 ! meiosis I GO:0007127 52 32 1,000 0,028077 0,14069087 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,028077 0,14038502 ! positive regulation of cell activation GO:0050867 120 81 2,000 0,02877593 0,14356754 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 2,000 0,0296946 0,14783025 GO:0060348|bone development, ! sister chromatid segregation GO:0000819 46 33 1,000 0,02973081 0,14769084 ! ear morphogenesis GO:0042471 42 33 1,000 0,02973081 0,14737254 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 1,000 0,02973081 0,14705561 ! sphingoid metabolic process GO:0046519 47 33 1,000 0,02973081 0,14674004 ! nucleus organization GO:0006997 49 33 1,000 0,02973081 0,14642583 ! female gonad development GO:0008585 49 33 1,000 0,02973081 0,14611295 ! lipid homeostasis GO:0055088 55 33 1,000 0,02973081 0,14580141 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,02973081 0,14549119 ! cytokinesis GO:0000910 52 33 1,000 0,02973081 0,14518229 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,03142251 0,15311818 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,03142251 0,15279446 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,03142251 0,15247211 ! female gamete generation GO:0007292 43 34 1,000 0,03142251 0,15215112 ! embryonic organ development GO:0048568 45 34 1,000 0,03142251 0,15183147 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 0,03142251 0,15151317 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 0,03254283 0,15658685 ! Golgi vesicle transport GO:0048193 138 85 2,000 0,03254283 0,15625995 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,0331514 0,15885044 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,0331514 0,15852019 ! Rho protein signal transduction GO:0007266 51 35 1,000 0,0331514 0,15819131 ! pigment metabolic process GO:0042440 61 35 1,000 0,0331514 0,15786379 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 2,000 0,03451819 0,16403272 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 0,03451819 0,1636945 ! response to reactive oxygen species GO:0000302 55 36 1,000 0,03491674 0,16524385 ! neural tube development GO:0021915 50 36 1,000 0,03491674 0,16490454 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,03491674 0,16456662 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 1,000 0,03491674 0,16423009 ! anatomical structure homeostasis GO:0060249 136 88 2,000 0,03552872 0,16676745 ! protein processing GO:0016485 114 88 2,000 0,03552872 0,1664278 ! regulation of T cell activation GO:0050863 128 89 2,000 0,03655442 0,1708845 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 1,000 0,03671786 0,17130035 GO:0006956|complement activation, ! regulation of protein secretion GO:0050708 51 37 1,000 0,03671786 0,17095358 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 0,03855404 0,17913997 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,03855404 0,1787788 ! monocarboxylic acid transport GO:0015718 62 38 1,000 0,03855404 0,17841909 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,04024009 0,18584781 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,04024009 0,18547537 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,04024009 0,18510442 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,04024009 0,18473495 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,04024009 0,18436695 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,04024009 0,18400042 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,04024009 0,18363534 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,04024009 0,18327171 ! sleep GO:0030431 11 5 0,000 0,04024009 0,18290951 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,04024009 0,18254874 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,04024009 0,18218939 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,04024009 0,18183146 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,04024009 0,18147492 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,04024009 0,18111979 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,04024009 0,18076604 ! tongue development GO:0043586 6 5 0,000 0,04024009 0,18041367 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,04024009 0,18006267 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,04024009 0,17971303 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,04024009 0,17936475 ! cobalt ion transport GO:0006824 9 5 0,000 0,04024009 0,17901782 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,04024009 0,17867222 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,04024009 0,17832796 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,04024009 0,17798502 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,04024009 0,1776434 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,04024009 0,17730309 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,04024009 0,17696407 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,04024009 0,17662636 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,04024009 0,17628993 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,04024009 0,17595477 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,04024009 0,17562089 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,04024009 0,17528828 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,04024009 0,17495692 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,04024009 0,17462681 ! malate metabolic process GO:0006108 7 5 0,000 0,04024009 0,17429795 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,04024009 0,17397032 ! behavioral response to pain GO:0048266 7 5 0,000 0,04024009 0,17364392 ! clathrin coat assembly GO:0048268 11 5 0,000 0,04024009 0,17331875 ! phototransduction, visible light GO:0007603 6 5 0,000 0,04024009 0,17299479 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,04024009 0,17267204 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,04024009 0,17235049 ! mating behavior GO:0007617 6 5 0,000 0,04024009 0,17203013 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,04024009 0,17171097 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,04024009 0,17139298 ! rhythmic behavior GO:0007622 12 5 0,000 0,04024009 0,17107618 ! copulation GO:0007620 7 5 0,000 0,04024009 0,17076054 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,04024009 0,17044606 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,04024009 0,17013274 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,04024009 0,16982057 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,04024009 0,16950954 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,04024009 0,16919965 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,04024009 0,1688909 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,04024009 0,16858326 ! response to protozoan GO:0001562 9 5 0,000 0,04024009 0,16827675 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,04024009 0,16797134 ! lymph vessel development GO:0001945 7 5 0,000 0,04024009 0,16766705 ! endochondral ossification GO:0001958 12 5 0,000 0,04024009 0,16736385 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,04024009 0,16706175 ! parathyroid gland development GO:0060017 8 5 0,000 0,04024009 0,16676074 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,04024009 0,16646081 ! anagen GO:0042640 6 5 0,000 0,04024009 0,16616196 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,04024009 0,16586418 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,04024009 0,16556746 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,04024009 0,16527181 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,04024009 0,1649772 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,04024009 0,16468365 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,04024009 0,16439114 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,04024009 0,16409967 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,04024009 0,16380922 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,04024009 0,16351981 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,04024009 0,16323141 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,04024009 0,16294403 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,04024009 0,16265766 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,04024009 0,1623723 ! ovulation GO:0030728 6 5 0,000 0,04024009 0,16208794 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,04024009 0,16180456 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,04024009 0,16152218 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,04024009 0,16124079 ! response to pH GO:0009268 9 5 0,000 0,04024009 0,16096037 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,04024009 0,16068092 ! proline biosynthetic process GO:0006561 6 5 0,000 0,04024009 0,16040245 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,04024009 0,16012493 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,04024009 0,15984838 ! polyol catabolic process GO:0046174 7 5 0,000 0,04024009 0,15957278 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,04024009 0,15929813 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,04024009 0,15902442 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,04024009 0,15875165 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,04024009 0,15847981 ! nerve growth factor processing GO:0032455 7 5 0,000 0,04024009 0,15820891 ! urea metabolic process GO:0019627 6 5 0,000 0,04024009 0,15793893 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,04024009 0,15766987 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,04024009 0,15740172 ! neutrophil activation GO:0042119 5 5 0,000 0,04024009 0,15713448 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,04024009 0,15686815 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,04024009 0,15660273 ! response to food GO:0032094 5 5 0,000 0,04024009 0,15633819 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,04024009 0,15607455 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,04024009 0,1558118 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,04024009 0,15554993 ! forebrain neuron development GO:0021884 7 5 0,000 0,04024009 0,15528894 ! melanosome organization GO:0032438 7 5 0,000 0,04024009 0,15502883 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,04024009 0,15476958 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04024009 0,1545112 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,04024009 0,15425369 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,04024009 0,15399702 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,04024009 0,15374121 ! nucleoside transport GO:0015858 6 5 0,000 0,04024009 0,15348625 ! nucleoside salvage GO:0043174 7 5 0,000 0,04024009 0,15323214 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,04024009 0,15297886 ! folic acid transport GO:0015884 9 5 0,000 0,04024009 0,15272642 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,04024009 0,15247481 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,04024009 0,15222403 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,04024009 0,15197407 ! depyrimidination GO:0045008 8 5 0,000 0,04024009 0,15172494 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,04024009 0,15147661 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,04024009 0,1512291 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,04024009 0,1509824 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,04024009 0,1507365 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,04024009 0,1504914 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,04024009 0,1502471 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,04024009 0,15000358 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,04024009 0,14976086 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,04024009 0,14951892 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,04024009 0,14927776 ! centrosome duplication GO:0051298 5 5 0,000 0,04024009 0,14903738 ! response to UV-C GO:0010225 6 5 0,000 0,04024009 0,14879777 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,04024009 0,14855893 ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,04024009 0,14832085 ! regulation of dendrite development GO:0050773 12 5 0,000 0,04024009 0,14808354 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,04024009 0,14784698 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,04024009 0,14761118 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,04024009 0,14737613 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,04024009 0,14714183 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,04024009 0,14690827 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,04024009 0,14667545 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,04024009 0,14644337 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,04024009 0,14621202 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,04024009 0,14598141 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,04024009 0,14575151 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,04024009 0,14552234 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,04024009 0,14529389 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,04024009 0,14506616 ! neural tube patterning GO:0021532 6 5 0,000 0,04024009 0,14483914 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,04024009 0,14461283 ! histone demethylation GO:0016577 9 5 0,000 0,04024009 0,14438722 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04024009 0,14416232 ! regulation of sterol transport GO:0032371 7 5 0,000 0,04024009 0,14393812 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,04024009 0,14371461 ! establishment of planar polarity GO:0001736 6 5 0,000 0,04024009 0,1434918 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,04024009 0,14326968 ! transcription termination GO:0006353 8 5 0,000 0,04024009 0,14304824 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,04024009 0,14282749 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,04024009 0,14260741 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,04024009 0,14238802 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,04024009 0,1421693 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,04024009 0,14195124 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,04024009 0,14173386 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,04024009 0,14151714 GO:0015991|ATP hydrolysis coupled proton transport, ! protein destabilization GO:0031648 6 5 0,000 0,04024009 0,14130109 ! apical protein localization GO:0045176 6 5 0,000 0,04024009 0,14108569 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,04024009 0,14087095 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,04024009 0,14065686 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,04024009 0,14044342 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,04024009 0,14023062 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,04024009 0,14001847 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,04024009 0,13980697 ! determination of adult lifespan GO:0008340 8 5 0,000 0,04024009 0,1395961 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04024009 0,13938586 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,04024009 0,13917626 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,04024009 0,13896728 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,04024009 0,13875894 ! neural plate development GO:0001840 6 5 0,000 0,04024009 0,13855121 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,04024009 0,13834411 ! regulation of sensory perception GO:0051931 6 5 0,000 0,04024009 0,13813763 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,04024009 0,13793176 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,04024009 0,1377265 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,04024009 0,13752186 ! sensory cilium assembly GO:0035058 6 5 0,000 0,04024009 0,13731782 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,04024009 0,13711439 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,04024009 0,13691155 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,04024009 0,13670932 ! spindle assembly GO:0051225 5 5 0,000 0,04024009 0,13650769 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,04024009 0,13630664 GO:0022011|myelination in the peripheral nervous system, ! protein amino acid prenylation GO:0018346 9 5 0,000 0,04024009 0,13610619 ! organ regeneration GO:0031100 7 5 0,000 0,04024009 0,13590633 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,04024009 0,13570705 ! carnitine metabolic process GO:0009437 5 5 0,000 0,04024009 0,13550836 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,04024009 0,13531025 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,04024009 0,13511272 GO:0055081|anion homeostasis, ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 0,0404246 0,13553438 ! male sex differentiation GO:0046661 53 39 1,000 0,0404246 0,1353371 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 1,000 0,0404246 0,13514039 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 1,000 0,0404246 0,13494425 ! synapse organization GO:0050808 55 39 1,000 0,0404246 0,13474867 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 0,0408081 0,13583015 ! polysaccharide metabolic process GO:0005976 129 93 2,000 0,0408081 0,13563386 ! carbohydrate catabolic process GO:0016052 121 93 2,000 0,0408081 0,13543814 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,04232887 0,14028301 ! B cell differentiation GO:0030183 62 40 1,000 0,04232887 0,14008117 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,04232887 0,1398799 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,04232887 0,13967921 ! T cell differentiation GO:0030217 65 40 1,000 0,04232887 0,1394791 ! regulation of binding GO:0051098 151 95 2,000 0,04302474 0,14156924 ! angiogenesis GO:0001525 149 95 2,000 0,04302474 0,141367 ! in utero embryonic development GO:0001701 147 96 2,000 0,04415531 0,14487478 ! protein maturation GO:0051604 129 96 2,000 0,04415531 0,1446684 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,04426618 0,14482535 ! glucose transport GO:0015758 52 41 1,000 0,04426618 0,14461964 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,04426618 0,1444145 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 0,04426618 0,14420995 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,04426618 0,14400597 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,04623587 0,15020128 ! cellular component disassembly GO:0022411 64 42 1,000 0,04623587 0,14998943 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,04623587 0,14977818 ! hexose transport GO:0008645 54 42 1,000 0,04623587 0,14956752 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,04623587 0,14935746 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 1,000 0,04623587 0,14914798 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,04623587 0,14893909 ! tRNA transcription GO:0009304 11 6 0,000 0,04809302 0,15470483 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04809302 0,15448876 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04809302 0,15427329 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04809302 0,15405843 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04809302 0,15384416 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04809302 0,15363049 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04809302 0,15341741 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04809302 0,15320492 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04809302 0,15299302 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04809302 0,1527817 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04809302 0,15257097 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04809302 0,15236081 ! prostate gland development GO:0030850 9 6 0,000 0,04809302 0,15215124 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04809302 0,15194224 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04809302 0,15173382 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04809302 0,15152596 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04809302 0,15131867 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04809302 0,15111196 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04809302 0,1509058 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04809302 0,15070021 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04809302 0,15049517 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04809302 0,15029069 ! neuron adhesion GO:0007158 9 6 0,000 0,04809302 0,15008677 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,04809302 0,1498834 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04809302 0,14968058 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04809302 0,14947831 ! signal peptide processing GO:0006465 8 6 0,000 0,04809302 0,14927659 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04809302 0,14907541 ! mRNA stabilization GO:0048255 15 6 0,000 0,04809302 0,14887477 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04809302 0,14867467 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04809302 0,1484751 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04809302 0,14827607 ! opsonization GO:0008228 8 6 0,000 0,04809302 0,14807758 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04809302 0,14787961 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04809302 0,14768218 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04809302 0,14748527 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04809302 0,14728888 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04809302 0,14709302 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04809302 0,14689768 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04809302 0,14670285 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04809302 0,14650854 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04809302 0,14631475 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04809302 0,14612147 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04809302 0,1459287 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04809302 0,14573643 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04809302 0,14554467 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04809302 0,14535342 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04809302 0,14516267 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04809302 0,14497241 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04809302 0,14478266 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04809302 0,1445934 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04809302 0,14440464 ! thymic T cell selection GO:0045061 12 6 0,000 0,04809302 0,14421636 ! protein lipoylation GO:0009249 10 6 0,000 0,04809302 0,14402858 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04809302 0,14384129 ! drug transport GO:0015893 6 6 0,000 0,04809302 0,14365448 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04809302 0,14346816 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04809302 0,14328232 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04809302 0,14309696 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04809302 0,14291208 ! histidine metabolic process GO:0006547 6 6 0,000 0,04809302 0,14272768 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04809302 0,14254375 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04809302 0,1423603 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,04809302 0,14217732 ! adenohypophysis development GO:0021984 10 6 0,000 0,04809302 0,1419948 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04809302 0,14181276 ! hyperosmotic response GO:0006972 8 6 0,000 0,04809302 0,14163118 ! microtubule nucleation GO:0007020 10 6 0,000 0,04809302 0,14145007 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04809302 0,14126941 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04809302 0,14108922 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04809302 0,14090949 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04809302 0,14073022 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,04809302 0,1405514 ! response to dietary excess GO:0002021 7 6 0,000 0,04809302 0,14037303 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04809302 0,14019512 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04809302 0,14001766 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04809302 0,13984065 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04809302 0,13966408 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04809302 0,13948796 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04809302 0,13931228 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04809302 0,13913705 ! neuron apoptosis GO:0051402 8 6 0,000 0,04809302 0,13896225 ! organic alcohol transport GO:0015850 9 6 0,000 0,04809302 0,13878789 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04809302 0,13861397 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04809302 0,13844049 ! male sex determination GO:0030238 9 6 0,000 0,04809302 0,13826744 ! carnitine transport GO:0015879 8 6 0,000 0,04809302 0,13809482 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04809302 0,13792263 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04809302 0,13775087 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04809302 0,13757954 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04809302 0,13740864 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04809302 0,13723815 ! parturition GO:0007567 12 6 0,000 0,04809302 0,13706809 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04809302 0,13689845 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04809302 0,13672924 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04809302 0,13656043 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04809302 0,13639205 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04809302 0,13622408 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04809302 0,13605652 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04809302 0,13588938 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04809302 0,13572264 ! macrophage differentiation GO:0030225 10 6 0,000 0,04809302 0,13555631 ! astrocyte development GO:0014002 14 6 0,000 0,04809302 0,13539039 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04809302 0,13522488 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04809302 0,13505977 ! interaction with symbiont GO:0051702 8 6 0,000 0,04809302 0,13489506 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04809302 0,13473076 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04809302 0,13456685 ! eating behavior GO:0042755 6 6 0,000 0,04809302 0,13440334 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04809302 0,13424023 ! DNA topological change GO:0006265 8 6 0,000 0,04809302 0,13407752 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04809302 0,1339152 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04809302 0,13375327 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04809302 0,13359173 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04809302 0,13343058 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04809302 0,13326982 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04809302 0,13310945 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04809302 0,13294946 ! gas homeostasis GO:0033483 11 6 0,000 0,04809302 0,13278986 ! hair follicle maturation GO:0048820 7 6 0,000 0,04809302 0,13263064 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04809302 0,1324718 ! Schwann cell development GO:0014044 14 6 0,000 0,04809302 0,13231334 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04809302 0,13215526 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04809302 0,13199756 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04809302 0,13184023 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04809302 0,13168328 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04809302 0,1315267 ! histone ubiquitination GO:0016574 7 6 0,000 0,04809302 0,13137049 ! regulation of meiosis GO:0040020 10 6 0,000 0,04809302 0,13121465 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04809302 0,13105918 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04809302 0,13090408 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04809302 0,13074935 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04809302 0,13059498 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04809302 0,13044098 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04809302 0,13028734 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04809302 0,13013406 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04809302 0,12998114 ! receptor internalization GO:0031623 9 6 0,000 0,04809302 0,12982858 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04809302 0,12967638 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04809302 0,12952453 ! protein deubiquitination GO:0016579 8 6 0,000 0,04809302 0,12937304 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04809302 0,12922191 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04809302 0,12907112 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04809302 0,12892069 ! axonal fasciculation GO:0007413 9 6 0,000 0,04809302 0,12877061 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04809302 0,12862087 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04809302 0,12847149 ! regulation of viral transcription GO:0046782 8 6 0,000 0,04809302 0,12832245 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04809302 0,12817376 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04809302 0,12802541 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04809302 0,1278774 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04809302 0,12772974 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04809302 0,12758241 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04809302 0,12743543 ! adult feeding behavior GO:0008343 6 6 0,000 0,04809302 0,12728878 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04809302 0,12714247 ! pigment granule transport GO:0051904 12 6 0,000 0,04809302 0,1269965 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04809302 0,12685086 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04809302 0,12670556 ! catecholamine transport GO:0051937 7 6 0,000 0,04809302 0,12656058 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04809302 0,12641594 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04809302 0,12627163 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04809302 0,12612765 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,04809302 0,125984 ! protein prenylation GO:0018342 10 6 0,000 0,04809302 0,12584067 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04809302 0,12569767 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04809302 0,125555 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04809302 0,12541264 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04809302 0,12527061 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04809302 0,1251289 ! positive regulation of binding GO:0051099 59 43 1,000 0,04823729 0,12536245 ! activation of caspase activity GO:0006919 65 43 1,000 0,04823729 0,12522096 ! vesicle organization GO:0016050 79 43 1,000 0,04823729 0,12507979 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 2,000 0,04882455 0,12645997 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,05026979 0,13005683 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,05026979 0,1299107 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,05026979 0,1297649 ! cell maturation GO:0048469 60 45 1,000 0,05233275 0,1349387 ! response to UV GO:0009411 75 46 1,000 0,05442553 0,14017773 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,05588214 0,14376838 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05588214 0,14360775 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05588214 0,14344747 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05588214 0,14328755 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05588214 0,14312799 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05588214 0,14296878 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05588214 0,14280992 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05588214 0,14265142 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05588214 0,14249327 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05588214 0,14233547 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05588214 0,14217802 ! reproductive behavior GO:0019098 12 7 0,000 0,05588214 0,14202092 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05588214 0,14186416 ! oligopeptide transport GO:0006857 11 7 0,000 0,05588214 0,14170775 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05588214 0,14155169 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05588214 0,14139596 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05588214 0,14124058 ! RNA methylation GO:0001510 11 7 0,000 0,05588214 0,14108555 ! pericardium development GO:0060039 8 7 0,000 0,05588214 0,14093085 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05588214 0,14077649 ! fibril organization GO:0043206 13 7 0,000 0,05588214 0,14062246 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05588214 0,14046878 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05588214 0,14031543 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05588214 0,14016241 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05588214 0,14000973 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05588214 0,13985738 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05588214 0,13970536 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05588214 0,13955367 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05588214 0,13940231 ! chemosensory behavior GO:0007635 9 7 0,000 0,05588214 0,13925128 ! microtubule bundle formation GO:0001578 8 7 0,000 0,05588214 0,13910058 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05588214 0,1389502 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05588214 0,13880014 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05588214 0,13865041 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05588214 0,138501 ! reflex GO:0060004 12 7 0,000 0,05588214 0,13835192 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05588214 0,13820315 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05588214 0,13805471 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05588214 0,13790658 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05588214 0,13775877 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05588214 0,13761128 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05588214 0,1374641 ! spinal cord patterning GO:0021511 7 7 0,000 0,05588214 0,13731724 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05588214 0,13717069 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05588214 0,13702445 ! adrenal gland development GO:0030325 17 7 0,000 0,05588214 0,13687852 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05588214 0,13673291 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05588214 0,1365876 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05588214 0,1364426 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05588214 0,13629791 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05588214 0,13615353 ! endosome organization GO:0007032 10 7 0,000 0,05588214 0,13600945 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05588214 0,13586568 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05588214 0,13572221 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05588214 0,13557904 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05588214 0,13543618 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05588214 0,13529361 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05588214 0,13515135 ! galactose metabolic process GO:0006012 10 7 0,000 0,05588214 0,13500938 ! vesicle fusion GO:0006906 15 7 0,000 0,05588214 0,13486771 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05588214 0,13472634 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05588214 0,13458527 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05588214 0,13444449 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05588214 0,134304 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05588214 0,13416381 ! retinol metabolic process GO:0042572 9 7 0,000 0,05588214 0,13402391 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,05588214 0,1338843 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05588214 0,13374499 ! rRNA modification GO:0000154 12 7 0,000 0,05588214 0,13360596 ! protein heterooligomerization GO:0051291 10 7 0,000 0,05588214 0,13346722 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05588214 0,13332877 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,05588214 0,1331906 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05588214 0,13305272 ! intermediate filament organization GO:0045109 11 7 0,000 0,05588214 0,13291513 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05588214 0,13277782 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05588214 0,1326408 ! fibrinolysis GO:0042730 9 7 0,000 0,05588214 0,13250405 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,05588214 0,13236759 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05588214 0,13223141 ! response to tropane GO:0014073 13 7 0,000 0,05588214 0,13209551 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! melanosome localization GO:0032400 10 7 0,000 0,05588214 0,13195989 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05588214 0,13182455 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05588214 0,13168948 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05588214 0,13155469 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05588214 0,13142018 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05588214 0,13128594 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05588214 0,13115197 ! mast cell activation GO:0045576 9 7 0,000 0,05588214 0,13101828 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05588214 0,13088486 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,05588214 0,13075171 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05588214 0,13061883 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05588214 0,13048623 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,05588214 0,13035389 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,05588214 0,13022182 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,05588214 0,13009001 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05588214 0,12995848 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05588214 0,1298272 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05588214 0,1296962 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05588214 0,12956546 ! regulation of lipid transport GO:0032368 13 7 0,000 0,05588214 0,12943498 ! response to tumor cell GO:0002347 12 7 0,000 0,05588214 0,12930476 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05588214 0,12917481 ! neuroblast proliferation GO:0007405 13 7 0,000 0,05588214 0,12904511 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05588214 0,12891568 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,05588214 0,12878651 ! diuresis GO:0030146 12 7 0,000 0,05588214 0,12865759 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05588214 0,12852893 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05588214 0,12840053 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,05588214 0,12827239 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05588214 0,1281445 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05588214 0,12801686 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05588214 0,12788948 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,05588214 0,12776236 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05588214 0,12763548 ! lymph node development GO:0048535 9 7 0,000 0,05588214 0,12750886 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05588214 0,12738249 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05588214 0,12725637 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05588214 0,1271305 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05588214 0,12700487 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05588214 0,1268795 ! ATP catabolic process GO:0006200 10 7 0,000 0,05588214 0,12675437 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05588214 0,12662949 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,05588214 0,12650485 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05588214 0,12638046 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05588214 0,12625632 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05588214 0,12613242 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05588214 0,12600876 ! muscle adaptation GO:0043500 12 7 0,000 0,05588214 0,12588534 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05588214 0,12576216 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05588214 0,12563923 ! retina homeostasis GO:0001895 9 7 0,000 0,05588214 0,12551654 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05588214 0,12539408 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05588214 0,12527186 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05588214 0,12514989 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05588214 0,12502814 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05588214 0,12490664 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,05588214 0,12478537 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05588214 0,12466434 ! respiratory electron transport chain GO:0022904 59 47 1,000 0,05654751 0,12602643 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,05654751 0,12590443 ! endocrine system development GO:0035270 83 47 1,000 0,05654751 0,12578267 ! covalent chromatin modification GO:0016569 75 47 1,000 0,05654751 0,12566114 ! glutamine family amino acid metabolic process GO:0009064 59 47 1,000 0,05654751 0,12553984 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,05869809 0,13018863 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 1,000 0,05869809 0,13006321 ! gastrulation GO:0007369 73 48 1,000 0,05869809 0,12993803 ! heart morphogenesis GO:0003007 65 48 1,000 0,05869809 0,12981309 ! regulation of DNA replication GO:0006275 75 48 1,000 0,05869809 0,12968839 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,05869809 0,12956393 GO:0019724|B cell mediated immunity, ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,05869809 0,12943971 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,05869809 0,12931572 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,06087667 0,13398692 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,06087667 0,13385883 ! germ cell development GO:0007281 68 49 1,000 0,06087667 0,13373098 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 1,000 0,06308264 0,13844473 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06360797 0,13946457 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06360797 0,13933175 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,06360797 0,13919918 ! axon extension GO:0048675 11 8 0,000 0,06360797 0,13906686 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,06360797 0,13893479 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06360797 0,13880298 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06360797 0,13867141 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06360797 0,13854009 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06360797 0,13840902 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,06360797 0,1382782 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,06360797 0,13814763 ! phosphate transport GO:0006817 10 8 0,000 0,06360797 0,1380173 ! N-glycan processing GO:0006491 12 8 0,000 0,06360797 0,13788722 ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06360797 0,13775738 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06360797 0,13762779 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,06360797 0,13749844 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,06360797 0,13736933 ! succinate metabolic process GO:0006105 14 8 0,000 0,06360797 0,13724047 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,06360797 0,13711184 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06360797 0,13698346 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,06360797 0,13685532 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06360797 0,13672742 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06360797 0,13659976 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06360797 0,13647233 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,06360797 0,13634514 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,06360797 0,13621819 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,06360797 0,13609148 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06360797 0,135965 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06360797 0,13583875 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06360797 0,13571274 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,06360797 0,13558697 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,06360797 0,13546142 ! astrocyte differentiation GO:0048708 16 8 0,000 0,06360797 0,13533611 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,06360797 0,13521103 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06360797 0,13508618 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06360797 0,13496157 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,06360797 0,13483718 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06360797 0,13471302 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,06360797 0,13458909 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06360797 0,13446538 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,06360797 0,13434191 ! macrophage activation GO:0042116 12 8 0,000 0,06360797 0,13421866 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06360797 0,13409563 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06360797 0,13397284 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,06360797 0,13385026 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,06360797 0,13372791 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,06360797 0,13360579 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06360797 0,13348388 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06360797 0,1333622 ! ruffle organization GO:0031529 11 8 0,000 0,06360797 0,13324074 ! osteoblast development GO:0002076 13 8 0,000 0,06360797 0,13311951 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06360797 0,13299849 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06360797 0,13287769 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06360797 0,13275711 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06360797 0,13263675 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06360797 0,13251661 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,06360797 0,13239669 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,06360797 0,13227698 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06360797 0,13215749 GO:0030204|chondroitin sulfate metabolic process, ! regulation of gliogenesis GO:0014013 20 8 0,000 0,06360797 0,13203821 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,06360797 0,13191915 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06360797 0,1318003 ! segment specification GO:0007379 10 8 0,000 0,06360797 0,13168167 ! cellular extravasation GO:0045123 11 8 0,000 0,06360797 0,13156325 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06360797 0,13144505 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06360797 0,13132705 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06360797 0,13120927 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,06360797 0,1310917 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06360797 0,13097434 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,06360797 0,13085719 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06360797 0,13074025 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,06360797 0,13062352 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06360797 0,13050699 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06360797 0,13039068 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06360797 0,13027457 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06360797 0,13015866 ! icosanoid secretion GO:0032309 12 8 0,000 0,06360797 0,13004297 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,06360797 0,12992748 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06360797 0,12981219 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06360797 0,12969711 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06360797 0,12958223 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06360797 0,12946756 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06360797 0,12935308 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06360797 0,12923881 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06360797 0,12912475 ! sterol catabolic process GO:0016127 9 8 0,000 0,06360797 0,12901088 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06360797 0,12889721 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,06360797 0,12878375 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06360797 0,12867048 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06360797 0,12855741 ! prophase GO:0051324 11 8 0,000 0,06360797 0,12844455 ! S phase GO:0051320 8 8 0,000 0,06360797 0,12833188 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06360797 0,1282194 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,06360797 0,12810713 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06360797 0,12799505 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06360797 0,12788316 ! hormone catabolic process GO:0042447 13 8 0,000 0,06360797 0,12777147 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06360797 0,12765998 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,06360797 0,12754868 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,06360797 0,12743758 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06360797 0,12732666 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,06360797 0,12721595 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06360797 0,12710542 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06360797 0,12699508 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06360797 0,12688494 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,06360797 0,12677499 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06360797 0,12666523 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06360797 0,12655566 ! regulation of embryonic development GO:0045995 16 8 0,000 0,06360797 0,12644627 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06360797 0,12633708 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06360797 0,12622807 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,06360797 0,12611926 ! adult behavior GO:0030534 80 51 1,000 0,06531543 0,12939318 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,06531543 0,12928183 ! aging GO:0007568 79 52 1,000 0,06757445 0,1336382 ! sphingolipid metabolic process GO:0006665 72 52 1,000 0,06757445 0,13352339 ! establishment of organelle localization GO:0051656 85 52 1,000 0,06757445 0,13340878 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,06985913 0,13780103 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,06985913 0,13768295 ! kidney development GO:0001822 90 53 1,000 0,06985913 0,13756507 ! cell projection assembly GO:0030031 76 53 1,000 0,06985913 0,13744739 ! regulation of developmental growth GO:0048638 13 9 0,000 0,07127102 0,14010542 ! telencephalon cell migration GO:0022029 16 9 0,000 0,07127102 0,13998578 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,07127102 0,13986633 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,07127102 0,1397471 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,07127102 0,13962806 ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,07127102 0,13950923 ! elastic fiber assembly GO:0048251 13 9 0,000 0,07127102 0,1393906 ! social behavior GO:0035176 14 9 0,000 0,07127102 0,13927217 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,07127102 0,13915394 ! artery development GO:0060840 19 9 0,000 0,07127102 0,13903591 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 15 9 0,000 0,07127102 0,13891809 ! response to pain GO:0048265 16 9 0,000 0,07127102 0,13880046 ! protein complex disassembly GO:0043241 17 9 0,000 0,07127102 0,13868303 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,07127102 0,1385658 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,07127102 0,13844877 ! lung alveolus development GO:0048286 17 9 0,000 0,07127102 0,13833193 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,07127102 0,1382153 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,07127102 0,13809886 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,07127102 0,13798261 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,07127102 0,13786656 ! ventral spinal cord development GO:0021517 11 9 0,000 0,07127102 0,13775071 ! protein targeting to ER GO:0045047 19 9 0,000 0,07127102 0,13763505 ! endoderm development GO:0007492 12 9 0,000 0,07127102 0,13751958 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,07127102 0,13740431 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,07127102 0,13728923 ! arginine catabolic process GO:0006527 10 9 0,000 0,07127102 0,13717435 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,07127102 0,13705965 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,07127102 0,13694515 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,07127102 0,13683084 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,07127102 0,13671672 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,07127102 0,13660279 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,07127102 0,13648904 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,07127102 0,13637549 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,07127102 0,13626213 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07127102 0,13614896 ! mannose metabolic process GO:0006013 9 9 0,000 0,07127102 0,13603597 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,07127102 0,13592317 ! receptor clustering GO:0043113 15 9 0,000 0,07127102 0,13581056 ! epithelial cell development GO:0002064 10 9 0,000 0,07127102 0,13569813 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,07127102 0,13558589 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,07127102 0,13547384 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,07127102 0,13536197 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,07127102 0,13525028 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,07127102 0,13513878 ! motor axon guidance GO:0008045 14 9 0,000 0,07127102 0,13502747 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,07127102 0,13491633 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,07127102 0,13480538 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,07127102 0,13469461 ! blastoderm segmentation GO:0007350 11 9 0,000 0,07127102 0,13458403 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,07127102 0,13447362 ! DNA ligation GO:0006266 14 9 0,000 0,07127102 0,1343634 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,07127102 0,13425335 ! response to amine stimulus GO:0014075 13 9 0,000 0,07127102 0,13414349 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,07127102 0,1340338 ! erythrocyte development GO:0048821 11 9 0,000 0,07127102 0,1339243 ! renal water homeostasis GO:0003091 14 9 0,000 0,07127102 0,13381497 ! postreplication repair GO:0006301 11 9 0,000 0,07127102 0,13370583 ! mRNA cleavage GO:0006379 13 9 0,000 0,07127102 0,13359686 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,07127102 0,13348806 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,07127102 0,13337945 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,07127102 0,13327101 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,07127102 0,13316275 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,07127102 0,13305466 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,07127102 0,13294675 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,07127102 0,13283901 ! acid secretion GO:0046717 14 9 0,000 0,07127102 0,13273145 ! musculoskeletal movement GO:0050881 11 9 0,000 0,07127102 0,13262406 GO:0050879|multicellular organismal movement, ! methionine biosynthetic process GO:0009086 10 9 0,000 0,07127102 0,13251685 ! purine base metabolic process GO:0006144 18 9 0,000 0,07127102 0,13240981 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,07127102 0,13230294 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,07127102 0,13219624 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,07127102 0,13208972 ! detection of calcium ion GO:0005513 13 9 0,000 0,07127102 0,13198337 ! blastocyst formation GO:0001825 12 9 0,000 0,07127102 0,13187719 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,07127102 0,13177118 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,07127102 0,13166534 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,07127102 0,13155967 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,07127102 0,13145416 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07127102 0,13134883 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,07127102 0,13124367 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,07127102 0,13113867 ! prepulse inhibition GO:0060134 14 9 0,000 0,07127102 0,13103385 ! embryonic placenta development GO:0001892 12 9 0,000 0,07127102 0,13092919 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,07127102 0,13082469 ! insulin secretion GO:0030073 17 9 0,000 0,07127102 0,13072037 ! sequestering of metal ion GO:0051238 11 9 0,000 0,07127102 0,13061621 ! establishment of cell polarity GO:0030010 12 9 0,000 0,07127102 0,13051222 ! nucleus localization GO:0051647 15 9 0,000 0,07127102 0,13040839 ! regulation of synapse organization GO:0050807 12 9 0,000 0,07127102 0,13030472 ! localization within membrane GO:0051668 15 9 0,000 0,07127102 0,13020123 ! DNA catabolic process GO:0006308 67 54 1,000 0,07216891 0,1317369 ! detection of external stimulus GO:0009581 66 54 1,000 0,07216891 0,13163243 ! mesoderm development GO:0007498 76 55 1,000 0,07450323 0,13578243 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,07686154 0,13996956 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07887179 0,1435167 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07887179 0,14340325 ! neuron fate specification GO:0048665 11 10 0,000 0,07887179 0,14328998 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07887179 0,14317688 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07887179 0,14306397 ! thyroid gland development GO:0030878 19 10 0,000 0,07887179 0,14295123 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,07887179 0,14283867 ! synapsis GO:0007129 13 10 0,000 0,07887179 0,14272629 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07887179 0,14261408 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,07887179 0,14250205 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07887179 0,1423902 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,07887179 0,14227852 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07887179 0,14216702 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,07887179 0,14205569 ! androgen metabolic process GO:0008209 13 10 0,000 0,07887179 0,14194453 ! phospholipid efflux GO:0033700 16 10 0,000 0,07887179 0,14183355 ! hippocampus development GO:0021766 19 10 0,000 0,07887179 0,14172274 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,07887179 0,14161211 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07887179 0,14150165 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,07887179 0,14139136 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07887179 0,14128124 ! pathogenesis GO:0009405 13 10 0,000 0,07887179 0,14117129 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07887179 0,14106152 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07887179 0,14095191 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07887179 0,14084248 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,07887179 0,14073321 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,07887179 0,14062412 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,07887179 0,14051519 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07887179 0,14040643 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07887179 0,14029784 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07887179 0,14018942 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07887179 0,14008117 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07887179 0,13997308 ! response to X-ray GO:0010165 16 10 0,000 0,07887179 0,13986516 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07887179 0,13975741 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07887179 0,13964982 ! forebrain cell migration GO:0021885 17 10 0,000 0,07887179 0,13954239 ! lipid digestion GO:0044241 15 10 0,000 0,07887179 0,13943514 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07887179 0,13932804 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07887179 0,13922111 ! UV protection GO:0009650 14 10 0,000 0,07887179 0,13911435 ! entry into host cell GO:0030260 20 10 0,000 0,07887179 0,13900775 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07887179 0,13890131 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07887179 0,13879504 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,07887179 0,13868892 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07887179 0,13858297 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07887179 0,13847719 ! response to dsRNA GO:0043331 18 10 0,000 0,07887179 0,13837156 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07887179 0,13826609 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07887179 0,13816079 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07887179 0,13805564 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,07887179 0,13795066 ! cranial nerve development GO:0021545 12 10 0,000 0,07887179 0,13784583 ! fucose catabolic process GO:0019317 16 10 0,000 0,07887179 0,13774116 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,07887179 0,13763666 GO:0006305|DNA alkylation, ! protein sumoylation GO:0016925 12 10 0,000 0,07887179 0,13753231 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07887179 0,13742812 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07887179 0,13732408 ! zymogen activation GO:0031638 14 10 0,000 0,07887179 0,13722021 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07887179 0,13711649 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07887179 0,13701292 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,07887179 0,13690952 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07887179 0,13680627 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,07887179 0,13670317 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07887179 0,13660024 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07887179 0,13649745 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07887179 0,13639482 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07887179 0,13629235 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,07887179 0,13619002 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07887179 0,13608786 ! detection of bacterium GO:0016045 10 10 0,000 0,07887179 0,13598584 ! activation of innate immune response GO:0002218 10 10 0,000 0,07887179 0,13588398 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07887179 0,13578227 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,07887179 0,13568071 ! developmental induction GO:0031128 13 10 0,000 0,07887179 0,13557931 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,07887179 0,13547805 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07887179 0,13537695 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07887179 0,135276 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,07924331 0,13581192 ! carbohydrate transport GO:0008643 74 57 1,000 0,07924331 0,1357108 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,07924331 0,13560982 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 1,000 0,07924331 0,135509 ! coenzyme biosynthetic process GO:0009108 67 57 1,000 0,07924331 0,13540832 ! membrane lipid metabolic process GO:0006643 79 57 1,000 0,07924331 0,1353078 ! secondary metabolic process GO:0019748 84 57 1,000 0,07924331 0,13520742 ! developmental maturation GO:0021700 75 57 1,000 0,07924331 0,13510719 ! gonad development GO:0008406 79 57 1,000 0,07924331 0,13500711 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,08164798 0,13900101 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,08164798 0,13889819 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,08164798 0,13879554 ! activation of MAPK activity GO:0000187 84 59 1,000 0,08407505 0,14281581 ! rRNA transcription GO:0009303 17 11 0,000 0,08641078 0,14667513 ! respiratory burst GO:0045730 14 11 0,000 0,08641078 0,14656696 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,08641078 0,14645896 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,08641078 0,14635111 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,08641078 0,14624342 ! virus-host interaction GO:0019048 17 11 0,000 0,08641078 0,14613588 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,08641078 0,14602851 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,08641078 0,14592129 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,08641078 0,14581424 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,08641078 0,14570733 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,08641078 0,14560059 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,08641078 0,145494 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,08641078 0,14538757 ! T cell proliferation GO:0042098 20 11 0,000 0,08641078 0,14528129 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,08641078 0,14517517 ! bone resorption GO:0045453 16 11 0,000 0,08641078 0,1450692 ! regulated secretory pathway GO:0045055 14 11 0,000 0,08641078 0,14496339 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,08641078 0,14485773 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,08641078 0,14475222 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,08641078 0,14464687 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,08641078 0,14454167 ! syncytium formation GO:0006949 15 11 0,000 0,08641078 0,14443663 ! plasma membrane organization GO:0007009 18 11 0,000 0,08641078 0,14433174 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,08641078 0,144227 ! mitotic spindle organization GO:0007052 15 11 0,000 0,08641078 0,14412241 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,08641078 0,14401797 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,08641078 0,14391369 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,08641078 0,14380955 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,08641078 0,14370557 ! adult heart development GO:0007512 11 11 0,000 0,08641078 0,14360174 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,08641078 0,14349805 ! L-glutamate transport GO:0015813 16 11 0,000 0,08641078 0,14339452 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,08641078 0,14329113 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,08641078 0,1431879 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,08641078 0,14308481 ! stem cell development GO:0048864 29 11 0,000 0,08641078 0,14298187 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,08641078 0,14287908 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,08641078 0,14277644 ! vasoconstriction GO:0042310 15 11 0,000 0,08641078 0,14267394 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,08641078 0,14257159 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,08641078 0,14246939 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,08641078 0,14236734 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,08641078 0,14226543 ! ribosome assembly GO:0042255 13 11 0,000 0,08641078 0,14216366 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,08641078 0,14206205 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,08641078 0,14196057 ! nucleosome positioning GO:0016584 13 11 0,000 0,08641078 0,14185925 ! regulation of isotype switching GO:0045191 19 11 0,000 0,08641078 0,14175806 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,08641078 0,14165702 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,08641078 0,14155613 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,08641078 0,14145538 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,08641078 0,14135477 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,08641078 0,1412543 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,08641078 0,14115398 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,08641078 0,1410538 ! male genitalia development GO:0030539 13 11 0,000 0,08641078 0,14095376 ! cholesterol efflux GO:0033344 19 11 0,000 0,08641078 0,14085386 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,08641078 0,14075411 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,08641078 0,1406545 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,08641078 0,14055502 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,08641078 0,14045569 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,08641078 0,1403565 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,08641078 0,14025745 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,08641078 0,14015854 ! lysogeny GO:0030069 18 11 0,000 0,08641078 0,14005976 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,08641078 0,13996113 ! acrosome reaction GO:0007340 13 11 0,000 0,08641078 0,13986263 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,08641078 0,13976428 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,08652397 0,13984901 GO:0035113|embryonic appendage morphogenesis, ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,08899425 0,14374072 ! meiosis GO:0007126 96 61 1,000 0,08899425 0,14363985 GO:0051327|M phase of meiotic cell cycle, ! urogenital system development GO:0001655 101 61 1,000 0,08899425 0,14353912 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,08899425 0,14343853 ! neurotransmitter transport GO:0006836 81 62 1,000 0,09148538 0,1473504 ! respiratory tube development GO:0030323 99 62 1,000 0,09148538 0,14724729 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,09148538 0,14714432 ! meiotic cell cycle GO:0051321 97 62 1,000 0,09148538 0,14704149 ! organelle localization GO:0051640 96 62 1,000 0,09148538 0,14693881 ! lactation GO:0007595 20 12 0,000 0,0938885 0,15069334 ! reproductive cellular process GO:0048610 14 12 0,000 0,0938885 0,15058826 ! tRNA modification GO:0006400 14 12 0,000 0,0938885 0,15048332 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,0938885 0,15037852 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,0938885 0,15027388 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,0938885 0,15016937 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,0938885 0,15006502 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,0938885 0,14996081 ! non-recombinational repair GO:0000726 19 12 0,000 0,0938885 0,14985674 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,0938885 0,14975282 ! peroxisomal transport GO:0043574 21 12 0,000 0,0938885 0,14964904 ! cartilage condensation GO:0001502 18 12 0,000 0,0938885 0,1495454 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,0938885 0,14944191 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,0938885 0,14933856 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0938885 0,14923536 ! heart looping GO:0001947 15 12 0,000 0,0938885 0,14913229 ! palate development GO:0060021 15 12 0,000 0,0938885 0,14902937 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,0938885 0,14892659 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0938885 0,14882396 ! arginine metabolic process GO:0006525 13 12 0,000 0,0938885 0,14872146 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,0938885 0,14861911 ! methionine metabolic process GO:0006555 13 12 0,000 0,0938885 0,14851689 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,0938885 0,14841482 ! Golgi organization GO:0007030 18 12 0,000 0,0938885 0,14831288 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,0938885 0,14821109 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,0938885 0,14810944 ! monoamine transport GO:0015844 13 12 0,000 0,0938885 0,14800792 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0938885 0,14790655 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,0938885 0,14780531 ! L-amino acid transport GO:0015807 20 12 0,000 0,0938885 0,14770421 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,0938885 0,14760325 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0938885 0,14750243 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,0938885 0,14740175 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,0938885 0,1473012 ! cerebellum development GO:0021549 13 12 0,000 0,0938885 0,14720079 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0938885 0,14710052 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,0938885 0,14700038 ! histone acetylation GO:0016573 23 12 0,000 0,0938885 0,14690038 ! histone methylation GO:0016571 15 12 0,000 0,0938885 0,14680052 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,0938885 0,14670079 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,0938885 0,1466012 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,0938885 0,14650174 ! intestinal absorption GO:0050892 19 12 0,000 0,0938885 0,14640241 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,0938885 0,14630323 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0938885 0,14620417 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,0938885 0,14610525 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,0938885 0,14600646 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,0938885 0,14590781 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,0938885 0,14580929 ! response to cold GO:0009409 14 12 0,000 0,0938885 0,1457109 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,09652817 0,14970653 ! appendage morphogenesis GO:0035107 93 64 1,000 0,09652817 0,14960565 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 90 65 1,000 0,09907885 0,15345546 ! regulation of caspase activity GO:0043281 97 65 1,000 0,09907885 0,15335219 ! appendage development GO:0048736 94 65 1,000 0,09907885 0,15324906 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 1,000 0,09907885 0,15314607 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,09907885 0,15304322 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,10130544 0,15637753 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,10130544 0,15627265 ! cGMP metabolic process GO:0046068 16 13 0,000 0,10130544 0,15616791 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,10130544 0,15606331 ! water transport GO:0006833 17 13 0,000 0,10130544 0,15595885 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,10130544 0,15585453 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,10130544 0,15575035 ! lipid localization GO:0010876 24 13 0,000 0,10130544 0,15564631 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,10130544 0,1555424 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,10130544 0,15543864 ! organelle fusion GO:0048284 28 13 0,000 0,10130544 0,15533502 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,10130544 0,15523153 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,10130544 0,15512818 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,10130544 0,15502497 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,10130544 0,15492189 ! response to hexose stimulus GO:0009746 19 13 0,000 0,10130544 0,15481895 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,10130544 0,15471615 ! glutamate metabolic process GO:0006536 18 13 0,000 0,10130544 0,15461349 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,10130544 0,15451096 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,10130544 0,15440856 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,10130544 0,15430631 ! NAD metabolic process GO:0019674 21 13 0,000 0,10130544 0,15420418 ! bone mineralization GO:0030282 15 13 0,000 0,10130544 0,1541022 ! regulation of exocytosis GO:0017157 17 13 0,000 0,10130544 0,15400035 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,10130544 0,15389863 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,10130544 0,15379704 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,10130544 0,1536956 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,10130544 0,15359428 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,10130544 0,1534931 ! genitalia development GO:0048806 15 13 0,000 0,10130544 0,15339205 ! regulation of cellular pH GO:0030641 20 13 0,000 0,10130544 0,15329113 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,10130544 0,15319035 ! tissue regeneration GO:0042246 21 13 0,000 0,10130544 0,1530897 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,10130544 0,15298918 ! cofactor transport GO:0051181 19 13 0,000 0,10130544 0,15288879 ! NADP metabolic process GO:0006739 18 13 0,000 0,10130544 0,15278854 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,10130544 0,15268842 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,10130544 0,15258842 ! gas transport GO:0015669 18 13 0,000 0,10130544 0,15248856 ! regulation of RNA stability GO:0043487 28 13 0,000 0,10130544 0,15238883 ! heme biosynthetic process GO:0006783 20 13 0,000 0,10130544 0,15228923 ! regulation of axon extension GO:0030516 23 13 0,000 0,10130544 0,15218976 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,10130544 0,15209042 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,10130544 0,15199121 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,10130544 0,15189213 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,10130544 0,15179317 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,10130544 0,15169435 ! antigen processing and presentation GO:0019882 96 66 1,000 0,10164842 0,15210888 ! regulation of immune effector process GO:0002697 101 66 1,000 0,10164842 0,15200998 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,10423639 0,15577888 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,10423639 0,15567772 ! acute inflammatory response GO:0002526 92 68 1,000 0,1068423 0,15946612 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,1068423 0,15936271 ! rhythmic process GO:0048511 105 68 1,000 0,1068423 0,15925943 ! superoxide anion generation GO:0042554 18 14 0,000 0,10866209 0,16186711 ! neuron maturation GO:0042551 21 14 0,000 0,10866209 0,16176234 ! regulation of S phase GO:0033261 18 14 0,000 0,10866209 0,16165771 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,10866209 0,16155321 ! myotube differentiation GO:0014902 21 14 0,000 0,10866209 0,16144885 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,10866209 0,16134462 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,10866209 0,16124053 ! inositol metabolic process GO:0006020 20 14 0,000 0,10866209 0,16113657 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,10866209 0,16103274 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,10866209 0,16092905 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,10866209 0,16082549 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,10866209 0,16072207 ! gene silencing by RNA GO:0031047 20 14 0,000 0,10866209 0,16061878 ! response to cAMP GO:0051591 19 14 0,000 0,10866209 0,16051562 ! limbic system development GO:0021761 25 14 0,000 0,10866209 0,16041259 ! startle response GO:0001964 21 14 0,000 0,10866209 0,1603097 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,10866209 0,16020693 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,10866209 0,1601043 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,10866209 0,1600018 ! glycine metabolic process GO:0006544 22 14 0,000 0,10866209 0,15989944 ! pituitary gland development GO:0021983 23 14 0,000 0,10866209 0,1597972 ! cellular response to starvation GO:0009267 21 14 0,000 0,10866209 0,15969509 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,10866209 0,15959311 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,10866209 0,15949127 ! regulation of heart rate GO:0002027 23 14 0,000 0,10866209 0,15938955 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,10866209 0,15928797 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,10866209 0,15918651 ! embryo implantation GO:0007566 27 14 0,000 0,10866209 0,15908518 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,10866209 0,15898398 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,10866209 0,15888291 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,10866209 0,15878197 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,10866209 0,15868115 ! axon cargo transport GO:0008088 27 14 0,000 0,10866209 0,15858047 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,10866209 0,15847991 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,10866209 0,15837948 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,10866209 0,15827918 ! mRNA splice site selection GO:0006376 26 14 0,000 0,10866209 0,158179 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,10866209 0,15807895 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,10866209 0,15797903 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,10866209 0,15787923 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,10866209 0,15777956 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,10866209 0,15768001 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,10866209 0,15758059 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,10866209 0,1574813 ! cell killing GO:0001906 20 14 0,000 0,10866209 0,15738213 ! cilium assembly GO:0042384 20 14 0,000 0,10866209 0,15728308 ! peptide hormone secretion GO:0030072 23 14 0,000 0,10866209 0,15718416 ! eye development GO:0001654 111 70 1,000 0,11210611 0,16206415 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,11476311 0,16580097 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,11476311 0,16569689 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,11595894 0,16731842 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,11595894 0,16721352 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,11595894 0,16710875 ! skin development GO:0043588 25 15 0,000 0,11595894 0,16700411 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,11595894 0,1668996 ! lipid phosphorylation GO:0046834 23 15 0,000 0,11595894 0,16679523 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,11595894 0,16669098 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,11595894 0,16658686 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,11595894 0,16648287 ! bile acid metabolic process GO:0008206 22 15 0,000 0,11595894 0,16637902 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,11595894 0,16627529 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,11595894 0,16617169 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,11595894 0,16606822 ! centrosome cycle GO:0007098 16 15 0,000 0,11595894 0,16596488 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,11595894 0,16586167 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,11595894 0,16575859 ! cerebral cortex development GO:0021987 29 15 0,000 0,11595894 0,16565563 ! response to osmotic stress GO:0006970 22 15 0,000 0,11595894 0,1655528 ! vesicle coating GO:0006901 25 15 0,000 0,11595894 0,1654501 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,11595894 0,16534753 ! DNA integration GO:0015074 22 15 0,000 0,11595894 0,16524508 ! peptide secretion GO:0002790 27 15 0,000 0,11595894 0,16514277 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,11595894 0,16504057 ! regulation of vasodilation GO:0042312 24 15 0,000 0,11595894 0,16493851 ! neuron recognition GO:0008038 22 15 0,000 0,11595894 0,16483657 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,11595894 0,16473475 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,11595894 0,16463307 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,11595894 0,1645315 ! biomineral formation GO:0031214 18 15 0,000 0,11595894 0,16443007 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,11595894 0,16432875 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,11595894 0,16422757 ! organic cation transport GO:0015695 19 15 0,000 0,11595894 0,1641265 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,11595894 0,16402556 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,11595894 0,16392475 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,11595894 0,16382406 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 19 15 0,000 0,11595894 0,16372349 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,11595894 0,16362305 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,11743623 0,16560597 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,11743623 0,1655045 ! regulation of blood pressure GO:0008217 107 73 1,000 0,12012506 0,16919022 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,12012506 0,16908668 ! digestion GO:0007586 97 74 1,000 0,12282914 0,17278717 ! protein import into nucleus GO:0006606 118 74 1,000 0,12282914 0,17268156 ! protein secretion GO:0009306 27 16 0,000 0,12319647 0,17309217 ! hormone secretion GO:0046879 25 16 0,000 0,12319647 0,17298649 ! bone remodeling GO:0046849 24 16 0,000 0,12319647 0,17288095 ! endothelial cell migration GO:0043542 22 16 0,000 0,12319647 0,17277553 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,12319647 0,17267025 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,12319647 0,17256509 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,12319647 0,17246006 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,12319647 0,17235516 ! glial cell development GO:0021782 24 16 0,000 0,12319647 0,17225038 ! patterning of blood vessels GO:0001569 24 16 0,000 0,12319647 0,17214573 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,12319647 0,17204121 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,12319647 0,17193682 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,12319647 0,17183255 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,12319647 0,17172841 GO:0030968|endoplasmic reticulum unfolded protein response, ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,12319647 0,17162439 ! protein export from nucleus GO:0006611 24 16 0,000 0,12319647 0,17152051 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,12319647 0,17141674 ! DNA replication initiation GO:0006270 25 16 0,000 0,12319647 0,17131311 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,12319647 0,17120959 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,12319647 0,17110621 ! diencephalon development GO:0021536 25 16 0,000 0,12319647 0,17100294 ! neural crest cell migration GO:0001755 24 16 0,000 0,12319647 0,1708998 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,12319647 0,17079679 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,12319647 0,1706939 ! steroid catabolic process GO:0006706 22 16 0,000 0,12319647 0,17059114 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,12319647 0,17048849 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,12319647 0,17038597 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,12319647 0,17028358 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,12319647 0,17018131 ! sperm-egg recognition GO:0035036 16 16 0,000 0,12319647 0,17007916 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,12319647 0,16997713 ! nerve development GO:0021675 18 16 0,000 0,12319647 0,16987523 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,12319647 0,16977344 ! negative regulation of translation GO:0017148 22 16 0,000 0,12319647 0,16967178 ! nuclear import GO:0051170 121 75 1,000 0,12554807 0,17280704 ! cofactor biosynthetic process GO:0051188 92 75 1,000 0,12554807 0,17270368 ! amine biosynthetic process GO:0009309 97 76 1,000 0,12828141 0,17635819 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,12828141 0,17625284 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,13037515 0,1790226 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,13037515 0,17891578 ! negative regulation of defense response GO:0031348 19 17 0,000 0,13037515 0,17880909 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,13037515 0,17870253 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,13037515 0,1785961 ! glycerol metabolic process GO:0006071 20 17 0,000 0,13037515 0,17848979 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,13037515 0,17838361 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,13037515 0,17827756 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,13037515 0,17817163 ! signal complex assembly GO:0007172 29 17 0,000 0,13037515 0,17806583 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,13037515 0,17796015 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,13037515 0,1778546 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,13037515 0,17774917 ! memory GO:0007613 25 17 0,000 0,13037515 0,17764387 ! keratinization GO:0031424 17 17 0,000 0,13037515 0,17753869 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,13037515 0,17743364 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,13037515 0,17732871 ! retinoid metabolic process GO:0001523 22 17 0,000 0,13037515 0,17722391 GO:0016101|diterpenoid metabolic process, ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,13037515 0,17711923 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,13037515 0,17701467 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,13037515 0,17691024 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,13037515 0,17680593 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,13037515 0,17670174 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,13037515 0,17659767 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,13037515 0,17649373 ! membrane budding GO:0006900 29 17 0,000 0,13037515 0,17638991 ! heme metabolic process GO:0042168 27 17 0,000 0,13037515 0,17628621 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,13037515 0,17618264 ! body fluid secretion GO:0007589 27 17 0,000 0,13037515 0,17607918 ! stem cell differentiation GO:0048863 36 17 0,000 0,13037515 0,17597585 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,13037515 0,17587264 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,13037515 0,17576955 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,13037515 0,17566658 ! sensory perception of pain GO:0019233 23 17 0,000 0,13037515 0,17556373 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,13037515 0,175461 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,13037515 0,17535839 ! synaptogenesis GO:0007416 24 17 0,000 0,13037515 0,1752559 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,13037515 0,17515353 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,13037515 0,17505128 ! cell-cell junction organization GO:0045216 25 17 0,000 0,13037515 0,17494915 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,13037515 0,17484714 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,13037515 0,17474525 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,13037515 0,17464348 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,13037515 0,17454182 ! regulation of DNA binding GO:0051101 119 77 1,000 0,13102877 0,17531482 ! sex differentiation GO:0007548 105 77 1,000 0,13102877 0,17521289 ! protein ubiquitination GO:0016567 125 77 1,000 0,13102877 0,17511108 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,13378972 0,17869708 ! cellular respiration GO:0045333 107 79 1,000 0,13656388 0,18229653 ! T cell activation GO:0042110 134 79 1,000 0,13656388 0,18219079 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,13749547 0,18332729 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,13749547 0,18322108 ! positive regulation of translation GO:0045727 28 18 0,000 0,13749547 0,18311499 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,13749547 0,18300902 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,13749547 0,18290317 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,13749547 0,18279745 ! cAMP metabolic process GO:0046058 33 18 0,000 0,13749547 0,18269184 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,13749547 0,18258636 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,13749547 0,18248101 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,13749547 0,18237577 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,13749547 0,18227065 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,13749547 0,18216566 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,13749547 0,18206078 ! response to retinoic acid GO:0032526 25 18 0,000 0,13749547 0,18195603 ! pigmentation during development GO:0048066 31 18 0,000 0,13749547 0,1818514 ! central nervous system neuron development GO:0021954 30 18 0,000 0,13749547 0,18174689 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,13749547 0,18164249 ! fucose metabolic process GO:0006004 26 18 0,000 0,13749547 0,18153822 ! response to fungus GO:0009620 19 18 0,000 0,13749547 0,18143407 ! peptide cross-linking GO:0018149 31 18 0,000 0,13749547 0,18133004 ! heart process GO:0003015 27 18 0,000 0,13749547 0,18122612 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,13749547 0,18112233 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 35 18 0,000 0,13749547 0,18101865 ! somitogenesis GO:0001756 24 18 0,000 0,13749547 0,18091509 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,13749547 0,18081165 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,13749547 0,18070833 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,13749547 0,18060513 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,13749547 0,18050204 ! vitamin transport GO:0051180 24 18 0,000 0,13749547 0,18039908 ! hormone transport GO:0009914 27 18 0,000 0,13749547 0,18029623 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,13749547 0,18019349 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,13749547 0,18009088 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,13749547 0,17998838 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,13749547 0,179886 ! cell-cell recognition GO:0009988 20 18 0,000 0,13749547 0,17978373 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,13749547 0,17968158 ! regulation of glucose import GO:0046324 21 18 0,000 0,13749547 0,17957955 GO:0010827|regulation of glucose transport, ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,13749547 0,17947763 ! protein localization in nucleus GO:0034504 133 80 1,000 0,13935083 0,18179632 ! response to protein stimulus GO:0051789 111 81 1,000 0,14215019 0,18534322 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,14455789 0,18837572 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,14455789 0,18826906 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,14455789 0,18816251 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,14455789 0,18805608 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,14455789 0,18794978 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,14455789 0,18784359 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,14455789 0,18773752 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,14455789 0,18763158 ! sensory perception of taste GO:0050909 23 19 0,000 0,14455789 0,18752575 ! smooth muscle contraction GO:0006939 36 19 0,000 0,14455789 0,18742004 ! peroxisome organization GO:0007031 29 19 0,000 0,14455789 0,18731445 ! digestive system process GO:0022600 30 19 0,000 0,14455789 0,18720898 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,14455789 0,18710363 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,14455789 0,1869984 ! response to vitamin A GO:0033189 26 19 0,000 0,14455789 0,18689328 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,14455789 0,18678829 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,14455789 0,18668341 ! sex determination GO:0007530 29 19 0,000 0,14455789 0,18657865 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,14455789 0,18647401 ! plasma membrane fusion GO:0045026 23 19 0,000 0,14455789 0,18636948 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,14455789 0,18626507 ! cytolysis GO:0019835 20 19 0,000 0,14455789 0,18616078 ! vasodilation GO:0042311 33 19 0,000 0,14455789 0,18605661 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,14455789 0,18595255 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,14455789 0,1858486 ! sarcomere organization GO:0045214 23 19 0,000 0,14455789 0,18574478 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,14455789 0,18564107 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,14455789 0,18553747 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,14455789 0,185434 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,14455789 0,18533063 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,14455789 0,18522738 ! detection of stimulus GO:0051606 108 82 1,000 0,14496158 0,18564123 ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,14778462 0,18915115 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,15061892 0,19267159 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,15156289 0,19377134 ! iron ion transport GO:0006826 37 20 0,000 0,15156289 0,19366369 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,15156289 0,19355616 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,15156289 0,19344875 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,15156289 0,19334145 ! response to vitamin GO:0033273 29 20 0,000 0,15156289 0,19323428 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,15156289 0,19312723 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,15156289 0,19302029 ! spinal cord development GO:0021510 31 20 0,000 0,15156289 0,19291347 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,15156289 0,19280677 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,15156289 0,19270019 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,15156289 0,19259372 ! chromosome condensation GO:0030261 31 20 0,000 0,15156289 0,19248738 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,15156289 0,19238115 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,15156289 0,19227504 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,15156289 0,19216904 ! pallium development GO:0021543 38 20 0,000 0,15156289 0,19206316 ! DNA modification GO:0006304 28 20 0,000 0,15156289 0,1919574 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,15156289 0,19185176 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,15156289 0,19174623 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,15156289 0,19164081 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,15156289 0,19153552 ! collagen catabolic process GO:0030574 25 20 0,000 0,15156289 0,19143034 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,15156289 0,19132527 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,15156289 0,19122032 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,15156289 0,19111548 ! alditol metabolic process GO:0019400 24 20 0,000 0,15156289 0,19101076 ! actin filament-based movement GO:0030048 34 20 0,000 0,15156289 0,19090616 ! rRNA metabolic process GO:0016072 107 85 1,000 0,15346413 0,19319513 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,15346413 0,19308944 ! regulation of membrane potential GO:0042391 128 85 1,000 0,15346413 0,19298387 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,15346413 0,19287842 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,15851092 0,19911257 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,15851092 0,19900388 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,15851092 0,19889531 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,15851092 0,19878687 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,15851092 0,19867853 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,15851092 0,19857032 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,15851092 0,19846223 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,15851092 0,19835425 ! protein amino acid acylation GO:0043543 37 21 0,000 0,15851092 0,19824639 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,15851092 0,19813865 ! vesicle docking GO:0048278 27 21 0,000 0,15851092 0,19803102 ! phototransduction GO:0007602 25 21 0,000 0,15851092 0,19792351 ! dendrite development GO:0016358 35 21 0,000 0,15851092 0,19781612 ! visual behavior GO:0007632 39 21 0,000 0,15851092 0,19770885 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,15851092 0,19760169 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,15851092 0,19749464 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,15851092 0,19738772 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,15851092 0,1972809 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,15851092 0,19717421 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,15851092 0,19706763 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,15851092 0,19696116 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,15851092 0,19685481 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,15851092 0,19674858 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,15851092 0,19664245 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,15851092 0,19653645 ! immunoglobulin production GO:0002377 33 21 0,000 0,15851092 0,19643056 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,15851092 0,19632478 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,15851092 0,19621911 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,15851092 0,19611356 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,15851092 0,19600812 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,15851092 0,1959028 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,15851092 0,19579759 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,15851092 0,19569249 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,15851092 0,19558751 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,15851092 0,19548263 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,15851092 0,19537787 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,15851092 0,19527323 ! cellular defense response GO:0006968 102 87 1,000 0,1591858 0,19599964 ! female pregnancy GO:0007565 130 87 1,000 0,1591858 0,19589478 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,16494677 0,2028757 ! reproductive developmental process GO:0003006 127 89 1,000 0,16494677 0,20276727 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,16540244 0,20321881 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,16540244 0,20311032 ! viral genome replication GO:0019079 29 22 0,000 0,16540244 0,20300193 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,16540244 0,20289366 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,16540244 0,20278551 ! leukocyte adhesion GO:0007159 38 22 0,000 0,16540244 0,20267748 ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,16540244 0,20256955 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,16540244 0,20246175 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,16540244 0,20235405 ! vasculogenesis GO:0001570 33 22 0,000 0,16540244 0,20224648 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,16540244 0,20213901 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,16540244 0,20203166 ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,16540244 0,20192443 ! lysosome organization GO:0007040 37 22 0,000 0,16540244 0,20181731 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,16540244 0,2017103 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,16540244 0,2016034 ! regulation of behavior GO:0050795 38 22 0,000 0,16540244 0,20149662 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,16540244 0,20138995 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,16540244 0,2012834 ! membrane depolarization GO:0051899 35 22 0,000 0,16540244 0,20117695 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,16540244 0,20107062 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,16540244 0,20096441 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,16540244 0,2008583 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,16540244 0,20075231 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,16540244 0,20064642 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,16784112 0,2034974 ! response to virus GO:0009615 122 91 1,000 0,17074426 0,20690822 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,17223792 0,20860833 ! neuron fate commitment GO:0048663 32 23 0,000 0,17223792 0,20849854 ! myelination GO:0042552 35 23 0,000 0,17223792 0,20838886 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,17223792 0,2082793 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,17223792 0,20816985 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,17223792 0,20806052 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,17223792 0,2079513 ! vesicle targeting GO:0006903 32 23 0,000 0,17223792 0,20784219 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,17223792 0,2077332 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,17223792 0,20762433 ! interaction with host GO:0051701 37 23 0,000 0,17223792 0,20751557 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,17223792 0,20740692 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,17223792 0,20729839 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,17223792 0,20718997 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,17223792 0,20708166 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,17223792 0,20697347 ! pentose metabolic process GO:0019321 31 23 0,000 0,17223792 0,20686539 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,17223792 0,20675742 ! spermatid development GO:0007286 33 23 0,000 0,17223792 0,20664957 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,17223792 0,20654183 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,17223792 0,2064342 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,17223792 0,20632668 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,17223792 0,20621927 ! telomere organization GO:0032200 32 23 0,000 0,17223792 0,20611198 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,17223792 0,2060048 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,17223792 0,20589772 ! regulation of amine transport GO:0051952 38 23 0,000 0,17223792 0,20579076 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,17901781 0,21378035 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,17901781 0,21366941 ! initiation of viral infection GO:0019059 42 24 0,000 0,17901781 0,21355859 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,17901781 0,21344788 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,17901781 0,21333728 ! superoxide metabolic process GO:0006801 32 24 0,000 0,17901781 0,2132268 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,17901781 0,21311644 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,17901781 0,21300618 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,17901781 0,21289605 ! sperm motility GO:0030317 27 24 0,000 0,17901781 0,21278602 ! vacuole organization GO:0007033 39 24 0,000 0,17901781 0,21267611 ! neural crest cell development GO:0014032 39 24 0,000 0,17901781 0,21256632 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 56 24 0,000 0,17901781 0,21245663 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 0,000 0,17901781 0,21234706 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,17901781 0,2122376 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,17901781 0,21212826 ! glutathione metabolic process GO:0006749 29 24 0,000 0,17901781 0,21201903 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,17901781 0,21190991 ! electron transport chain GO:0022900 123 94 1,000 0,17950313 0,2123751 ! carboxylic acid transport GO:0046942 147 95 1,000 0,18243815 0,21573663 GO:0015849|organic acid transport, ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,18538034 0,21910317 ! response to light stimulus GO:0009416 153 96 1,000 0,18538034 0,21899064 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,18574254 0,21930588 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,18574254 0,21919335 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,18574254 0,21908095 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,18574254 0,21896866 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,18574254 0,21885648 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,18574254 0,21874442 ! peptide transport GO:0015833 43 25 0,000 0,18574254 0,21863247 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,18574254 0,21852064 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,18574254 0,21840892 ! phospholipid transport GO:0015914 35 25 0,000 0,18574254 0,21829732 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,18574254 0,21818583 ! detection of light stimulus GO:0009583 30 25 0,000 0,18574254 0,21807445 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,18574254 0,21796319 ! translational initiation GO:0006413 43 26 0,000 0,19241258 0,22567513 ! regulation of pH GO:0006885 36 26 0,000 0,19241258 0,22556011 ! circadian rhythm GO:0007623 42 26 0,000 0,19241258 0,2254452 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,19241258 0,22533041 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,19241258 0,22521574 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,19241258 0,22510118 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,19241258 0,22498675 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,19241258 0,22487242 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,19241258 0,22475822 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,19241258 0,22464413 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,19241258 0,22453015 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,19241258 0,22441629 ! regulation of coagulation GO:0050818 39 26 0,000 0,19241258 0,22430255 ! protein import GO:0017038 156 99 1,000 0,19424683 0,2263261 ! regulation of translation GO:0006417 151 100 1,000 0,19721463 0,22966767 ! protein localization in organelle GO:0033365 161 100 1,000 0,19721463 0,22955145 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,19902835 0,23154538 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,19902835 0,23142832 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,19902835 0,23131138 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,19902835 0,23119455 ! membrane docking GO:0022406 39 27 0,000 0,19902835 0,23107785 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,19902835 0,23096126 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,19902835 0,23084479 ! acute-phase response GO:0006953 42 27 0,000 0,19902835 0,23072844 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,19902835 0,2306122 ! myofibril assembly GO:0030239 36 27 0,000 0,19902835 0,23049608 GO:0055002|striated muscle cell development, ! natural killer cell activation GO:0030101 35 27 0,000 0,19902835 0,23038008 ! lipid oxidation GO:0034440 38 27 0,000 0,19902835 0,23026419 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,19902835 0,23014842 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,19902835 0,23003277 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,19902835 0,22991724 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,19902835 0,22980182 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,20559031 0,23725927 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,20559031 0,23714028 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,20559031 0,23702141 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,20559031 0,23690266 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,20559031 0,23678403 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,20559031 0,23666552 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,20559031 0,23654713 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,20559031 0,23642886 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,20559031 0,2363107 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,20559031 0,23619267 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,20559031 0,23607475 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,20559031 0,23595694 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,20559031 0,23583926 ! ensheathment of neurons GO:0007272 43 28 0,000 0,20559031 0,23572169 GO:0008366|axon ensheathment, ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,20559031 0,23560424 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,20559031 0,23548691 ! regulation of B cell activation GO:0050864 42 28 0,000 0,20559031 0,23536969 ! regulation of innate immune response GO:0045088 38 29 0,000 0,21209888 0,24270021 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,21209888 0,24257953 ! protein targeting to membrane GO:0006612 53 29 0,000 0,21209888 0,24245896 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,21209888 0,24233851 ! mismatch repair GO:0006298 34 29 0,000 0,21209888 0,24221819 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,21209888 0,24209798 ! muscle cell development GO:0055001 38 29 0,000 0,21209888 0,24197789 ! telencephalon development GO:0021537 52 29 0,000 0,21209888 0,24185792 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,21209888 0,24173807 ! eye morphogenesis GO:0048592 51 29 0,000 0,21209888 0,24161834 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,21209888 0,24149873 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,2185545 0,24872605 ! collagen metabolic process GO:0032963 40 30 0,000 0,2185545 0,24860304 ! organic anion transport GO:0015711 51 30 0,000 0,2185545 0,24848015 ! cholesterol transport GO:0030301 46 30 0,000 0,2185545 0,24835738 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,2185545 0,24823474 ! spliceosome assembly GO:0000245 49 30 0,000 0,2185545 0,24811221 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,2185545 0,24798981 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,2185545 0,24786753 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,2185545 0,24774536 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,2185545 0,24762332 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,2185545 0,2475014 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,22495759 0,25462719 ! negative regulation of secretion GO:0051048 49 31 0,000 0,22495759 0,25450194 ! mammary gland development GO:0030879 57 31 0,000 0,22495759 0,25437682 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,22495759 0,25425182 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,22495759 0,25412694 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,22495759 0,25400218 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,22495759 0,25387755 ! segmentation GO:0035282 41 31 0,000 0,22495759 0,25375304 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,22495759 0,25362865 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,22495759 0,25350438 ! cell fate specification GO:0001708 37 31 0,000 0,22495759 0,25338024 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,23130857 0,26040613 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,23130857 0,26027873 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,23130857 0,26015145 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,23130857 0,2600243 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,23130857 0,25989727 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,23130857 0,25977037 ! peripheral nervous system development GO:0007422 53 32 0,000 0,23130857 0,25964359 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,23130857 0,25951693 ! cytokine production GO:0001816 44 32 0,000 0,23130857 0,2593904 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,23130857 0,25926399 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,23130857 0,25913771 ! vesicle localization GO:0051648 47 32 0,000 0,23130857 0,25901155 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,23760788 0,26593582 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,23760788 0,26580648 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,23760788 0,26567726 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,23760788 0,26554816 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,23760788 0,26541919 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,23760788 0,26529035 ! actomyosin structure organization GO:0031032 43 33 0,000 0,23760788 0,26516163 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,23760788 0,26503304 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,23760788 0,26490457 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,23760788 0,26477622 ! regulation of proteolysis GO:0030162 50 33 0,000 0,23760788 0,264648 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,23760788 0,2645199 ! mRNA catabolic process GO:0006402 48 34 0,000 0,24385592 0,27134427 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,24385592 0,27121306 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,24385592 0,27108198 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,24385592 0,27095102 ! feeding behavior GO:0007631 45 34 0,000 0,24385592 0,27082019 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,24385592 0,27068949 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,24385592 0,27055891 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,24385592 0,27042845 ! neuron migration GO:0001764 46 34 0,000 0,24385592 0,27029813 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,24385592 0,27016793 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,24385592 0,27003785 ! polyol metabolic process GO:0019751 44 34 0,000 0,24385592 0,2699079 ! aerobic respiration GO:0009060 47 34 0,000 0,24385592 0,26977807 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,24385592 0,26964837 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,25005311 0,27636817 ! Notch signaling pathway GO:0007219 56 35 0,000 0,25005311 0,27623542 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,25005311 0,27610281 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,25005311 0,27597032 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,25005311 0,27583796 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,25005311 0,27570573 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,25005311 0,27557362 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,25005311 0,27544164 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,25005311 0,27530979 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,25619986 0,28194243 GO:0090047|positive regulation of transcription regulator activity, ! regulation of hormone secretion GO:0046883 48 36 0,000 0,25619986 0,2818076 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,25619986 0,28167289 ! negative regulation of binding GO:0051100 58 36 0,000 0,25619986 0,28153831 ! organic ether metabolic process GO:0018904 46 36 0,000 0,25619986 0,28140386 ! tissue remodeling GO:0048771 62 36 0,000 0,25619986 0,28126954 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,25619986 0,28113535 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,25619986 0,28100128 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,26229659 0,28755107 ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,26229659 0,28741408 ! learning GO:0007612 67 37 0,000 0,26229659 0,28727721 ! ion transmembrane transport GO:0034220 56 37 0,000 0,26229659 0,28714048 ! amino acid activation GO:0043038 52 37 0,000 0,26229659 0,28700388 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,26229659 0,2868674 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,26834368 0,29334148 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,26834368 0,29320212 ! phagocytosis GO:0006909 60 38 0,000 0,26834368 0,2930629 ! maintenance of location in cell GO:0051651 69 38 0,000 0,26834368 0,29292381 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,27434155 0,29932902 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,27434155 0,29918709 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,27434155 0,29904529 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,27434155 0,29890363 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,27434155 0,29876211 ! chromatin remodeling GO:0006338 68 39 0,000 0,27434155 0,29862072 ! JNK cascade GO:0007254 54 39 0,000 0,27434155 0,29847946 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,2802906 0,30480774 ! response to calcium ion GO:0051592 58 40 0,000 0,2802906 0,30466369 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,2802906 0,30451978 ! regulation of tube size GO:0035150 60 40 0,000 0,2802906 0,304376 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,2802906 0,30423236 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,2802906 0,30408885 ! peptide metabolic process GO:0006518 56 40 0,000 0,2802906 0,30394548 ! inner ear development GO:0048839 57 40 0,000 0,2802906 0,30380225 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,2802906 0,30365915 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,2802906 0,30351618 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,2802906 0,30337335 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,28619121 0,30961419 ! striated muscle contraction GO:0006941 62 41 0,000 0,28619121 0,30946863 ! biopolymer methylation GO:0043414 62 41 0,000 0,28619121 0,3093232 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,28619121 0,30917791 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,29204378 0,31535243 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,29204378 0,31520445 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,29204378 0,31505661 ! excretion GO:0007588 63 42 0,000 0,29204378 0,3149089 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,29204378 0,31476133 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,29204378 0,3146139 ! regulation of cell shape GO:0008360 78 42 0,000 0,29204378 0,31446661 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,29784869 0,32056715 ! neuromuscular process GO:0050905 79 43 0,000 0,29784869 0,32041721 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,29784869 0,32026741 ! tRNA processing GO:0008033 49 43 0,000 0,29784869 0,32011775 ! methylation GO:0032259 64 43 0,000 0,29784869 0,31996823 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,30360634 0,32600121 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,30360634 0,32584908 ! regulation of action potential GO:0001508 71 44 0,000 0,30360634 0,3256971 ! regulation of ion transport GO:0043269 57 44 0,000 0,30360634 0,32554526 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,30360634 0,32539356 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,30360634 0,325242 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,30360634 0,32509059 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,30360634 0,32493931 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,30360634 0,32478818 ! RNA catabolic process GO:0006401 64 45 0,000 0,3093171 0,33074353 ! positive regulation of defense response GO:0031349 59 45 0,000 0,3093171 0,33058984 ! regulation of translational initiation GO:0006446 64 45 0,000 0,3093171 0,33043629 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,3093171 0,33028289 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,3093171 0,33012962 ! cell recognition GO:0008037 58 45 0,000 0,3093171 0,3299765 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,3093171 0,32982352 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,31498136 0,33570766 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,31498136 0,33555217 ! cell redox homeostasis GO:0045454 63 46 0,000 0,31498136 0,33539682 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,31498136 0,33524162 ! histone modification GO:0016570 68 46 0,000 0,31498136 0,33508655 ! viral infectious cycle GO:0019058 71 47 0,000 0,32059949 0,3409056 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,32059949 0,34074807 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,32059949 0,34059068 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,32059949 0,34043344 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,32059949 0,34027634 ! chloride transport GO:0006821 67 48 0,000 0,32617186 0,34603103 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,32617186 0,3458715 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,32617186 0,34571211 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,32617186 0,34555287 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,32617186 0,34539377 ! regulation of endocytosis GO:0030100 63 48 0,000 0,32617186 0,34523482 ! nuclear export GO:0051168 69 48 0,000 0,32617186 0,34507602 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,33169884 0,35076199 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,33169884 0,3506008 ! sensory perception of smell GO:0007608 61 49 0,000 0,33169884 0,35043975 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,33169884 0,35027885 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,33169884 0,3501181 ! RNA elongation GO:0006354 62 49 0,000 0,33169884 0,34995749 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,33169884 0,34979704 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,33169884 0,34963673 ! cartilage development GO:0051216 70 49 0,000 0,33169884 0,34947656 ! maintenance of location GO:0051235 84 49 0,000 0,33169884 0,34931655 ! regulation of actin filament length GO:0030832 72 50 0,000 0,3371808 0,35492716 ! membrane fusion GO:0006944 80 50 0,000 0,3371808 0,3547648 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,3371808 0,35460258 ! lipid modification GO:0030258 73 50 0,000 0,3371808 0,35444052 ! proton transport GO:0015992 75 50 0,000 0,3371808 0,3542786 ! positive regulation of secretion GO:0051047 71 51 0,000 0,34261811 0,35982724 ! hydrogen transport GO:0006818 77 51 0,000 0,34261811 0,35966301 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,34261811 0,35949893 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,34261811 0,359335 ! transition metal ion transport GO:0000041 74 52 0,000 0,34801113 0,36482479 ! regulation of cellular component size GO:0032535 74 52 0,000 0,34801113 0,36465858 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,34801113 0,36449253 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,34801113 0,36432662 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,3533602 0,36975817 ! single fertilization GO:0007338 59 53 0,000 0,3533602 0,36959003 ! amino acid transport GO:0006865 84 54 0,000 0,3586657 0,37496868 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,3586657 0,37479832 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,3586657 0,37462811 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,3586657 0,37445806 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,3586657 0,37428816 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,3586657 0,37411842 ! exocytosis GO:0006887 74 55 0,000 0,36392797 0,37943532 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,36392797 0,3792634 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,36914736 0,3845285 ! camera-type eye development GO:0043010 88 57 0,000 0,37432421 0,38974454 ! viral reproductive process GO:0022415 87 58 0,000 0,37945888 0,39491196 ! lung development GO:0030324 94 59 0,000 0,38455171 0,40003118 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,38455171 0,39985033 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,38960303 0,40491955 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,38960303 0,40473666 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,38960303 0,40455393 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,38960303 0,40437137 ! fertilization GO:0009566 68 60 0,000 0,38960303 0,40418898 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,39461317 0,40920212 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,39461317 0,40901771 ! amine catabolic process GO:0009310 90 62 0,000 0,39958248 0,41398185 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,39958248 0,41379546 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,40451128 0,41871105 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,40451128 0,41852269 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,40451128 0,41833451 ! viral reproduction GO:0016032 92 63 0,000 0,40451128 0,41814649 ! regulation of lipase activity GO:0060191 109 63 0,000 0,40451128 0,41795865 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,4093999 0,42281984 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,4093999 0,42263006 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,4093999 0,42244046 ! respiratory system development GO:0060541 100 64 0,000 0,4093999 0,42225102 ! defense response to bacterium GO:0042742 73 65 0,000 0,41424867 0,42706048 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,4190579 0,4318249 ! axon guidance GO:0007411 99 66 0,000 0,4190579 0,43163152 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,4190579 0,43143831 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,42382793 0,43615402 ! learning or memory GO:0007611 123 68 0,000 0,42855906 0,4408255 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,42855906 0,44062844 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,42855906 0,44043156 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,42855906 0,44023485 ! inorganic anion transport GO:0015698 93 68 0,000 0,42855906 0,44003832 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,4332516 0,44465805 ! amine transport GO:0015837 101 70 0,000 0,43790589 0,44923441 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,43790589 0,44903412 ! regulation of catabolic process GO:0009894 106 70 0,000 0,43790589 0,44883402 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,44252221 0,45336351 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,44252221 0,45316166 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,44710089 0,45764666 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,44710089 0,45744308 ! negative regulation of transport GO:0051051 116 73 0,000 0,45164222 0,46188399 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,45164222 0,46167871 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,45614651 0,46607595 ! blood coagulation GO:0007596 116 75 0,000 0,46061405 0,47043176 GO:0050817|coagulation, ! tRNA metabolic process GO:0006399 95 76 0,000 0,46504516 0,4747465 ! response to unfolded protein GO:0006986 99 76 0,000 0,46504516 0,47453587 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,46944011 0,47880809 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,46944011 0,47859586 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,46944011 0,47838381 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,46944011 0,47817194 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,46944011 0,47796027 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,4737992 0,48218503 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,4737992 0,48197177 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,47812273 0,48615486 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,47812273 0,48594003 ! regulation of lyase activity GO:0051339 133 79 0,000 0,47812273 0,48572539 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,47812273 0,48551094 ! chromatin assembly GO:0031497 102 80 0,000 0,48241099 0,48964928 GO:0006334|nucleosome assembly, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,48241099 0,48943329 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,48666425 0,49353076 ! hemostasis GO:0007599 125 81 0,000 0,48666425 0,49331325 ! mRNA transport GO:0051028 121 81 0,000 0,48666425 0,49309593 ! regulation of neurological system process GO:0031644 122 81 0,000 0,48666425 0,49287881 ! vitamin metabolic process GO:0006766 103 81 0,000 0,48666425 0,49266187 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,49506692 0,50094761 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of defense response GO:0031347 117 84 0,000 0,4992169 0,50492474 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,4992169 0,5047028 ! sterol metabolic process GO:0016125 120 84 0,000 0,4992169 0,50448105 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,503333 0,50841717 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,50741551 0,51231592 ! nucleosome organization GO:0034728 114 87 0,000 0,51146469 0,51617762 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,51548082 0,52000258 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,51548082 0,51977461 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,51946416 0,5235616 ! hormone metabolic process GO:0042445 121 90 0,000 0,52341498 0,52731251 ! RNA localization GO:0006403 135 91 0,000 0,52733355 0,53102765 ! ATP metabolic process GO:0046034 137 91 0,000 0,52733355 0,53079525 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,53122011 0,53447343 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,53122011 0,53423973 ! DNA recombination GO:0006310 146 92 0,000 0,53122011 0,53400623 ! sulfur metabolic process GO:0006790 118 92 0,000 0,53122011 0,53377294 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,53507495 0,53741152 ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,54645159 0,54859828 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,54645159 0,54835892 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,54645159 0,54811978 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,55018203 0,55162104 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,55755174 0,55876645 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,55755174 0,55852309 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,56119151 0,56192446 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,56119151 0,56167993 ! divalent metal ion transport GO:0070838 171 100 0,000 0,56119151 0,56143561 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,56119151 0,56119151