pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1300-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of epidermis development GO:0045684 13 8 3,000 1,098E-07 2,643E-04 ! CTP metabolic process GO:0046036 9 9 3,000 1,967E-07 2,367E-04 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of epithelial cell proliferation GO:0050678 111 43 5,000 3,11E-07 2,494E-04 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 3,000 3,263E-07 1,962E-04 ! focal adhesion formation GO:0048041 35 12 3,000 7,614E-07 3,664E-04 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 3,000 7,614E-07 3,053E-04 ! regulation of epidermis development GO:0045682 19 13 3,000 1,094E-06 3,761E-04 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 3,000 1,524E-06 4,585E-04 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 3,000 2,068E-06 5,529E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 2,527E-06 6,08E-04 ! cellular glucose homeostasis GO:0001678 5 5 2,000 2,527E-06 5,527E-04 ! regulation of keratinocyte differentiation GO:0045616 6 5 2,000 2,527E-06 5,067E-04 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 3,000 3,57E-06 6,608E-04 ! epidermis morphogenesis GO:0048730 40 18 3,000 4,568E-06 7,85E-04 ! cell-substrate junction assembly GO:0007044 54 18 3,000 4,568E-06 7,327E-04 ! G1 phase GO:0051318 40 19 3,000 5,757E-06 8,657E-04 ! gliogenesis GO:0042063 88 41 4,000 6,217E-06 8,798E-04 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 3,000 7,16E-06 9,571E-04 ! regulation of epidermal cell differentiation GO:0045604 8 7 2,000 8,761E-06 1,109E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 1,07E-05 1,288E-03 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 3,000 1,289E-05 1,477E-03 ! UTP metabolic process GO:0046051 8 8 2,000 1,395E-05 1,526E-03 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! regulation of ossification GO:0030278 117 50 4,000 1,678E-05 1,755E-03 ! GTP metabolic process GO:0046039 9 9 2,000 2,083E-05 2,088E-03 ! regulation of chromosome organization GO:0033044 42 27 3,000 2,505E-05 2,411E-03 ! regulation of bone remodeling GO:0046850 137 57 4,000 3,198E-05 2,96E-03 ! positive regulation of cell migration GO:0030335 126 57 4,000 3,198E-05 2,85E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 3,369E-05 2,895E-03 ! regulation of tissue remodeling GO:0034103 140 58 4,000 3,482E-05 2,889E-03 ! cell junction assembly GO:0034329 78 30 3,000 3,853E-05 3,09E-03 ! interphase GO:0051325 213 98 5,000 4,017E-05 3,118E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 4,451E-05 3,347E-03 ! hindbrain development GO:0030902 61 32 3,000 5,006E-05 3,65E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 4,000 5,205E-05 3,683E-03 ! gland morphogenesis GO:0022612 29 12 2,000 5,379E-05 3,698E-03 ! digestive tract morphogenesis GO:0048546 26 12 2,000 5,379E-05 3,595E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of cell motion GO:0051272 146 64 4,000 5,617E-05 3,653E-03 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 3,000 6,392E-05 4,047E-03 ! negative regulation of cell growth GO:0030308 132 67 4,000 7,006E-05 4,322E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 7,523E-05 4,525E-03 ! cell junction organization GO:0034330 86 36 3,000 8,038E-05 4,717E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 8,07E-05 4,623E-03 ! hair follicle morphogenesis GO:0031069 26 14 2,000 8,816E-05 4,933E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 8,816E-05 4,821E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 8,968E-05 4,795E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 9,973E-05 5,216E-03 GO:0042593|glucose homeostasis, ! ribonucleoside metabolic process GO:0009119 55 40 3,000 1,223E-04 6,258E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 2,000 1,344E-04 6,735E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,94E-04 9,524E-03 ! negative regulation of growth GO:0045926 155 84 4,000 2,052E-04 9,875E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 2,119E-04 9,996E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 2,119E-04 9,803E-03 ! mitochondrion organization GO:0007005 148 86 4,000 2,291E-04 0,01040189 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 2,292E-04 0,01021429 ! estrogen receptor signaling pathway GO:0030520 38 19 2,000 2,292E-04 0,01002857 ! positive regulation of cell cycle GO:0045787 89 48 3,000 2,501E-04 0,01074726 ! response to alkaloid GO:0043279 38 20 2,000 2,684E-04 0,01133101 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,684E-04 0,01113564 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,684E-04 0,0109469 ! gut development GO:0048565 39 21 2,000 3,117E-04 0,01249971 ! positive regulation of growth GO:0045927 90 52 3,000 3,412E-04 0,01345744 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,992E-04 0,01549318 ! positive regulation of histone modification GO:0031058 5 5 1,000 3,992E-04 0,01524726 ! glial cell fate commitment GO:0021781 13 5 1,000 3,992E-04 0,01500902 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 1,000 3,992E-04 0,01477811 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 3,992E-04 0,0145542 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,992E-04 0,01433698 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 1,000 3,992E-04 0,01412614 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,992E-04 0,01392141 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 1,000 3,992E-04 0,01372253 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 1,000 3,992E-04 0,01352926 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 1,000 3,992E-04 0,01334135 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,992E-04 0,01315859 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,992E-04 0,01298078 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 1,000 3,992E-04 0,0128077 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! positive regulation of organ growth GO:0046622 6 5 1,000 3,992E-04 0,01263918 ! response to cadmium ion GO:0046686 7 5 1,000 3,992E-04 0,01247503 ! enteric nervous system development GO:0048484 8 5 1,000 3,992E-04 0,0123151 ! muscle cell proliferation GO:0033002 11 5 1,000 3,992E-04 0,01215921 ! B cell homeostasis GO:0001782 13 5 1,000 3,992E-04 0,01200722 ! regulation of hair follicle development GO:0051797 10 5 1,000 3,992E-04 0,01185898 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 11 5 1,000 3,992E-04 0,01171436 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 3,992E-04 0,01157322 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,992E-04 0,01143545 ! receptor biosynthetic process GO:0032800 7 5 1,000 3,992E-04 0,01130091 ! stem cell division GO:0017145 11 5 1,000 3,992E-04 0,0111695 GO:0048103|somatic stem cell division, ! positive regulation of cell adhesion GO:0045785 56 23 2,000 4,112E-04 0,01137163 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 4,112E-04 0,01124241 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 4,112E-04 0,01111609 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 4,112E-04 0,01099258 ! positive regulation of organelle organization GO:0010638 100 56 3,000 4,538E-04 0,01199816 ! cell cycle arrest GO:0007050 213 100 4,000 4,61E-04 0,01205655 ! response to starvation GO:0042594 42 25 2,000 5,29E-04 0,01368658 ! nucleoside metabolic process GO:0009116 81 60 3,000 5,907E-04 0,01511832 ! embryonic pattern specification GO:0009880 44 26 2,000 5,952E-04 0,01507523 ! molting cycle process GO:0022404 50 26 2,000 5,952E-04 0,01491819 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! insulin receptor signaling pathway GO:0008286 64 26 2,000 5,952E-04 0,0147644 ! positive regulation of nuclear division GO:0051785 40 26 2,000 5,952E-04 0,01461374 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 5,952E-04 0,01446613 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 5,963E-04 0,01434815 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 5,963E-04 0,01420609 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 5,963E-04 0,01406681 ! establishment of spindle localization GO:0051293 12 6 1,000 5,963E-04 0,01393024 GO:0051653|spindle localization, ! monocyte differentiation GO:0030224 12 6 1,000 5,963E-04 0,0137963 ! neural nucleus development GO:0048857 14 6 1,000 5,963E-04 0,0136649 ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 5,963E-04 0,01353599 ! response to copper ion GO:0046688 10 6 1,000 5,963E-04 0,01340948 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 5,963E-04 0,01328532 ! negative regulation of T cell differentiation GO:0045581 14 6 1,000 5,963E-04 0,01316344 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 5,963E-04 0,01304377 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 5,963E-04 0,01292626 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 1,000 5,963E-04 0,01281085 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 5,963E-04 0,01269748 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 1,000 5,963E-04 0,0125861 GO:0045625|regulation of T-helper 1 cell differentiation, ! fat cell differentiation GO:0045444 50 27 2,000 6,665E-04 0,01394462 ! regulation of homeostatic process GO:0032844 134 62 3,000 6,69E-04 0,01387681 ! regulation of mitosis GO:0007088 105 63 3,000 7,109E-04 0,01461839 GO:0051783|regulation of nuclear division, ! myeloid cell differentiation GO:0030099 111 65 3,000 8E-04 0,01631232 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 8,314E-04 0,01680932 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 8,314E-04 0,01666924 ! regulation of gluconeogenesis GO:0006111 7 7 1,000 8,314E-04 0,01653148 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 8,314E-04 0,01639597 ! lipoprotein transport GO:0042953 14 7 1,000 8,314E-04 0,01626267 ! organ growth GO:0035265 15 7 1,000 8,314E-04 0,01613152 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 8,314E-04 0,01600247 ! B cell lineage commitment GO:0002326 21 7 1,000 8,314E-04 0,01587547 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 1,000 8,314E-04 0,01575046 ! T cell lineage commitment GO:0002360 16 7 1,000 8,314E-04 0,01562741 ! peptidyl-threonine modification GO:0018210 25 7 1,000 8,314E-04 0,01550627 ! dopamine biosynthetic process GO:0042416 18 7 1,000 8,314E-04 0,01538699 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 8,314E-04 0,01526953 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 9,481E-04 0,01728193 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 1,002E-03 0,01811767 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,104E-03 0,01982007 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,104E-03 0,01967325 ! pigment granule organization GO:0048753 16 8 1,000 1,104E-03 0,01952859 ! ER overload response GO:0006983 12 8 1,000 1,104E-03 0,01938605 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 1,000 1,104E-03 0,01924557 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,104E-03 0,01910711 ! melanin metabolic process GO:0006582 15 8 1,000 1,104E-03 0,01897063 ! response to UV-B GO:0010224 16 8 1,000 1,104E-03 0,01883609 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,104E-03 0,01870344 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 1,104E-03 0,01857265 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 1,104E-03 0,01844367 ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 1,000 1,104E-03 0,01831647 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! regulation of T-helper 1 type immune response GO:0002825 9 8 1,000 1,104E-03 0,01819102 ! blastocyst growth GO:0001832 19 8 1,000 1,104E-03 0,01806727 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 1,174E-03 0,01909026 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 1,174E-03 0,01896214 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,209E-03 0,01938935 GO:0060326|cell chemotaxis, ! glial cell differentiation GO:0010001 63 34 2,000 1,32E-03 0,02102634 ! cell-matrix adhesion GO:0007160 163 75 3,000 1,367E-03 0,02163727 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,413E-03 0,0222248 ! cellular copper ion homeostasis GO:0006878 12 9 1,000 1,413E-03 0,02208049 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,413E-03 0,02193803 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 23 9 1,000 1,413E-03 0,0217974 ! regulation of histone modification GO:0031056 12 9 1,000 1,413E-03 0,02165857 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,413E-03 0,02152149 ! T cell selection GO:0045058 23 9 1,000 1,413E-03 0,02138613 ! retrograde transport, endosome to Golgi GO:0042147 24 9 1,000 1,413E-03 0,02125247 ! behavioral fear response GO:0001662 22 9 1,000 1,413E-03 0,02112047 GO:0002209|behavioral defense response, ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,413E-03 0,02099009 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,413E-03 0,02086132 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,413E-03 0,02073412 ! negative regulation of lymphocyte differentiation GO:0045620 19 9 1,000 1,413E-03 0,02060845 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,413E-03 0,02048431 ! positive regulation of ligase activity GO:0051351 124 77 3,000 1,507E-03 0,02171146 ! positive regulation of cell development GO:0010720 80 36 2,000 1,56E-03 0,02233973 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,56E-03 0,02220754 ! protein oligomerization GO:0051259 139 78 3,000 1,581E-03 0,02237048 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,657E-03 0,02331042 ! regulation of protein stability GO:0031647 73 37 2,000 1,69E-03 0,02363483 ! glycogen metabolic process GO:0005977 61 37 2,000 1,69E-03 0,02349821 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,759E-03 0,02432574 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,759E-03 0,02418674 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,759E-03 0,02404931 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,759E-03 0,02391344 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,759E-03 0,0237791 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,759E-03 0,02364625 ! positive regulation of heart contraction GO:0045823 16 10 1,000 1,759E-03 0,02351488 ! B cell proliferation GO:0042100 18 10 1,000 1,759E-03 0,02338497 ! copper ion homeostasis GO:0055070 13 10 1,000 1,759E-03 0,02325648 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,759E-03 0,02312939 ! salivary gland development GO:0007431 27 10 1,000 1,759E-03 0,02300369 ! midbrain development GO:0030901 13 10 1,000 1,759E-03 0,02287935 ! oocyte development GO:0048599 17 10 1,000 1,759E-03 0,02275634 ! response to nicotine GO:0035094 20 10 1,000 1,759E-03 0,02263465 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,816E-03 0,02324732 ! glucan metabolic process GO:0044042 62 38 2,000 1,826E-03 0,02324375 GO:0006073|cellular glucan metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,9E-03 0,02406324 ! regulation of ligase activity GO:0051340 142 84 3,000 2,076E-03 0,02614755 ! mesenchymal cell development GO:0014031 87 40 2,000 2,119E-03 0,02654801 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,141E-03 0,02669224 ! temperature homeostasis GO:0001659 17 11 1,000 2,141E-03 0,02655465 ! negative regulation of ossification GO:0030279 26 11 1,000 2,141E-03 0,02641848 ! regulation of organ growth GO:0046620 13 11 1,000 2,141E-03 0,02628369 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 2,141E-03 0,02615027 ! embryonic axis specification GO:0000578 18 11 1,000 2,141E-03 0,0260182 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 2,141E-03 0,02588745 ! oocyte differentiation GO:0009994 18 11 1,000 2,141E-03 0,02575801 ! thymus development GO:0048538 27 11 1,000 2,141E-03 0,02562986 ! embryonic gut development GO:0048566 15 11 1,000 2,141E-03 0,02550298 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 2,141E-03 0,02537735 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,439E-03 0,02876307 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 2,559E-03 0,03002946 ! positive regulation of cell growth GO:0030307 22 12 1,000 2,559E-03 0,02988369 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 2,559E-03 0,02973932 ! fear response GO:0042596 26 12 1,000 2,559E-03 0,02959635 ! protein homotetramerization GO:0051289 21 12 1,000 2,559E-03 0,02945474 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,559E-03 0,02931448 ! mRNA polyadenylation GO:0006378 23 12 1,000 2,559E-03 0,02917554 ! autonomic nervous system development GO:0048483 24 12 1,000 2,559E-03 0,02903792 ! T cell homeostasis GO:0043029 25 12 1,000 2,559E-03 0,0289016 ! spleen development GO:0048536 22 12 1,000 2,559E-03 0,02876654 ! regulation of RNA splicing GO:0043484 20 12 1,000 2,559E-03 0,02863274 ! regulation of cell adhesion GO:0030155 212 89 3,000 2,563E-03 0,0285459 ! energy reserve metabolic process GO:0006112 74 43 2,000 2,609E-03 0,02893269 ! regulation of cell cycle process GO:0010564 149 90 3,000 2,669E-03 0,02945413 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 2,000 2,787E-03 0,03062305 ! developmental growth GO:0048589 82 44 2,000 2,787E-03 0,03048385 ! glycolysis GO:0006096 65 45 2,000 2,973E-03 0,0323623 ! leukocyte migration GO:0050900 68 45 2,000 2,973E-03 0,03221652 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,973E-03 0,03207205 ! cell growth GO:0016049 84 45 2,000 2,973E-03 0,03192887 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 3,005E-03 0,03213116 GO:0010498|proteasomal protein catabolic process, ! positive regulation of lipid metabolic process GO:0045834 25 13 1,000 3,011E-03 0,03205696 ! pseudouridine synthesis GO:0001522 17 13 1,000 3,011E-03 0,03191574 ! endocrine pancreas development GO:0031018 22 13 1,000 3,011E-03 0,03177576 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 3,011E-03 0,031637 ! exocrine system development GO:0035272 32 13 1,000 3,011E-03 0,03149945 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,011E-03 0,03136309 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 3,011E-03 0,0312279 ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 3,011E-03 0,03109388 ! chromatin silencing GO:0006342 26 13 1,000 3,011E-03 0,030961 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 3,011E-03 0,03082925 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 3,011E-03 0,03069862 ! mRNA 3'-end processing GO:0031124 24 13 1,000 3,011E-03 0,03056909 ! transcription initiation GO:0006352 153 94 3,000 3,123E-03 0,03157041 ! pigmentation GO:0043473 100 46 2,000 3,165E-03 0,03186394 ! forebrain development GO:0030900 188 95 3,000 3,244E-03 0,03252306 ! endosome transport GO:0016197 108 47 2,000 3,365E-03 0,03359717 ! regulation of adaptive immune response GO:0002819 84 47 2,000 3,365E-03 0,03345834 ! protein homooligomerization GO:0051260 76 47 2,000 3,365E-03 0,03332065 ! leukocyte differentiation GO:0002521 202 96 3,000 3,369E-03 0,03321697 ! positive regulation of immune response GO:0050778 156 96 3,000 3,369E-03 0,0330814 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 3,000 3,496E-03 0,03419541 ! regulation of protein localization GO:0032880 176 97 3,000 3,496E-03 0,03405697 ! pteridine and derivative biosynthetic process GO:0042559 19 14 1,000 3,498E-03 0,03393951 ! RNA polyadenylation GO:0043631 30 14 1,000 3,498E-03 0,03380321 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,498E-03 0,033668 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,498E-03 0,03353386 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 3,498E-03 0,03340079 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 3,498E-03 0,03326877 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 3,498E-03 0,03313779 ! response to gamma radiation GO:0010332 28 14 1,000 3,498E-03 0,03300784 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,498E-03 0,0328789 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 3,498E-03 0,03275097 ! mitochondrial transport GO:0006839 82 48 2,000 3,573E-03 0,03332011 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 3,000 3,627E-03 0,03369505 ! skeletal muscle tissue development GO:0007519 186 99 3,000 3,761E-03 0,03480721 GO:0060538|skeletal muscle organ development, ! negative regulation of immune system process GO:0002683 95 50 2,000 4,011E-03 0,03697885 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 4,02E-03 0,03691344 ! positive regulation of cell size GO:0045793 27 15 1,000 4,02E-03 0,03677308 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 4,02E-03 0,03663379 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 4,02E-03 0,03649555 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 4,02E-03 0,03635835 ! muscle maintenance GO:0046716 26 15 1,000 4,02E-03 0,03622217 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 4,02E-03 0,03608702 ! dopamine metabolic process GO:0042417 35 15 1,000 4,02E-03 0,03595286 ! lymphocyte homeostasis GO:0002260 30 15 1,000 4,02E-03 0,03581971 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 4,02E-03 0,03568753 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 4,242E-03 0,03752611 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,575E-03 0,04031778 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 4,575E-03 0,04017064 ! protein polyubiquitination GO:0000209 34 16 1,000 4,575E-03 0,04002456 ! fructose metabolic process GO:0006000 25 16 1,000 4,575E-03 0,03987954 ! regulation of dephosphorylation GO:0035303 43 16 1,000 4,575E-03 0,03973557 ! negative regulation of immune response GO:0050777 35 16 1,000 4,575E-03 0,03959264 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 4,575E-03 0,03945073 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,575E-03 0,03930984 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,575E-03 0,03916994 ! defense response to virus GO:0051607 37 16 1,000 4,575E-03 0,03903104 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 4,728E-03 0,04019668 ! metencephalon development GO:0022037 30 17 1,000 5,163E-03 0,04374023 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 5,163E-03 0,04358675 ! adult walking behavior GO:0007628 33 17 1,000 5,163E-03 0,04343435 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 5,163E-03 0,04328301 ! regulation of viral genome replication GO:0045069 28 17 1,000 5,163E-03 0,04313273 ! myoblast differentiation GO:0045445 45 17 1,000 5,163E-03 0,04298348 ! regulation of survival gene product expression GO:0045884 33 17 1,000 5,163E-03 0,04283526 ! regulation of protein binding GO:0043393 33 17 1,000 5,163E-03 0,04268806 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 5,163E-03 0,04254187 ! neutrophil chemotaxis GO:0030593 27 17 1,000 5,163E-03 0,04239667 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 5,163E-03 0,04225247 ! aromatic compound biosynthetic process GO:0019438 24 17 1,000 5,163E-03 0,04210924 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 5,163E-03 0,04196698 ! RNA 3'-end processing GO:0031123 34 17 1,000 5,163E-03 0,04182567 ! microspike assembly GO:0030035 36 17 1,000 5,163E-03 0,04168532 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 5,163E-03 0,0415459 ! glucose catabolic process GO:0006007 82 55 2,000 5,246E-03 0,04207285 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 5,246E-03 0,04193307 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 5,246E-03 0,04179422 ! skeletal muscle fiber development GO:0048741 111 56 2,000 5,517E-03 0,04381022 ! glutamine metabolic process GO:0006541 29 18 1,000 5,784E-03 0,04577852 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 5,784E-03 0,04562842 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 5,784E-03 0,04547931 ! long-chain fatty acid transport GO:0015909 31 18 1,000 5,784E-03 0,04533117 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 5,784E-03 0,04518399 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 5,797E-03 0,04513611 ! muscle fiber development GO:0048747 112 57 2,000 5,797E-03 0,04499051 ! actin filament bundle formation GO:0051017 42 19 1,000 6,438E-03 0,04980397 ! neuromuscular junction development GO:0007528 34 19 1,000 6,438E-03 0,04964434 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 6,438E-03 0,04948573 ! cellular pigmentation GO:0033059 36 19 1,000 6,438E-03 0,04932813 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 6,438E-03 0,04917154 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 6,438E-03 0,04901593 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 6,438E-03 0,04886131 ! regulation of heart contraction GO:0008016 110 60 2,000 6,686E-03 0,05058423 ! positive regulation of ossification GO:0045778 47 20 1,000 7,123E-03 0,053725 ! pteridine and derivative metabolic process GO:0042558 29 20 1,000 7,123E-03 0,05355711 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 7,123E-03 0,05339026 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 7,123E-03 0,05322446 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 35 20 1,000 7,123E-03 0,05305967 ! cellular response to starvation GO:0009267 33 20 1,000 7,123E-03 0,05289591 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 7,123E-03 0,05273315 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 7,123E-03 0,05257139 ! negative regulation of T cell activation GO:0050868 40 20 1,000 7,123E-03 0,05241063 ! ear development GO:0043583 103 62 2,000 7,321E-03 0,053701 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 7,651E-03 0,05595474 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 7,84E-03 0,05716169 ! hindlimb morphogenesis GO:0035137 43 21 1,000 7,84E-03 0,056989 ! axis specification GO:0009798 38 21 1,000 7,84E-03 0,05681734 ! ovarian follicle development GO:0001541 35 21 1,000 7,84E-03 0,05664672 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 7,84E-03 0,05647712 ! cell aging GO:0007569 44 21 1,000 7,84E-03 0,05630853 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 7,84E-03 0,05614095 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 7,84E-03 0,05597436 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 7,84E-03 0,05580875 ! oogenesis GO:0048477 36 21 1,000 7,84E-03 0,05564412 ! collagen fibril organization GO:0030199 59 21 1,000 7,84E-03 0,05548047 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 7,84E-03 0,05531777 ! response to cytokine stimulus GO:0034097 63 21 1,000 7,84E-03 0,05515602 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 7,991E-03 0,05605013 ! positive regulation of bone remodeling GO:0046852 51 22 1,000 8,588E-03 0,06006762 GO:0034105|positive regulation of tissue remodeling, ! regeneration GO:0031099 41 22 1,000 8,588E-03 0,05989351 ! apoptotic nuclear changes GO:0030262 32 22 1,000 8,588E-03 0,05972041 ! ureteric bud development GO:0001657 43 22 1,000 8,588E-03 0,0595483 ! renal system process GO:0003014 41 22 1,000 8,588E-03 0,05937719 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 8,588E-03 0,05920705 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 8,588E-03 0,05903789 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 8,588E-03 0,05886969 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 8,588E-03 0,05870244 ! protein stabilization GO:0050821 39 22 1,000 8,588E-03 0,05853615 ! actin filament organization GO:0007015 148 66 2,000 8,695E-03 0,05909764 ! extracellular matrix organization GO:0030198 133 66 2,000 8,695E-03 0,05893116 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 9,061E-03 0,06123616 ! homeostasis of number of cells GO:0048872 114 67 2,000 9,061E-03 0,06106463 ! hexose catabolic process GO:0019320 104 67 2,000 9,061E-03 0,06089406 ! positive regulation of T cell activation GO:0050870 109 67 2,000 9,061E-03 0,06072444 ! adaptive immune response GO:0002250 119 67 2,000 9,061E-03 0,06055576 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 2,000 9,061E-03 0,06038802 ! response to ethanol GO:0045471 46 23 1,000 9,367E-03 0,06225682 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 9,367E-03 0,06208531 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of viral reproduction GO:0050792 38 23 1,000 9,367E-03 0,06191475 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 9,367E-03 0,06174512 ! fatty acid transport GO:0015908 44 23 1,000 9,367E-03 0,06157642 ! negative regulation of ligase activity GO:0051352 112 68 2,000 9,435E-03 0,06185543 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01017601 0,06653119 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01017601 0,06635088 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01017601 0,06617156 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 0,01017601 0,0659932 ! multicellular organismal response to stress GO:0033555 49 24 1,000 0,01017601 0,0658158 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 0,01017601 0,06563935 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 0,01017601 0,06546384 ! lymphocyte proliferation GO:0046651 48 24 1,000 0,01017601 0,06528927 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 0,01017601 0,06511563 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 1,000 0,01017601 0,06494291 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,01017601 0,0647711 ! protein tetramerization GO:0051262 52 24 1,000 0,01017601 0,0646002 ! humoral immune response GO:0006959 109 71 2,000 0,0106121 0,06719133 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01101488 0,06955851 ! receptor metabolic process GO:0043112 46 25 1,000 0,01101488 0,06937642 ! osteoblast differentiation GO:0001649 60 25 1,000 0,01101488 0,06919528 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01101488 0,06901508 ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01101488 0,06883582 ! neural tube closure GO:0001843 49 25 1,000 0,01101488 0,06865749 GO:0060606|tube closure, ! liver development GO:0001889 53 25 1,000 0,01101488 0,06848008 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 1,000 0,01188318 0,07368796 ! tube lumen formation GO:0035148 50 26 1,000 0,01188318 0,07349853 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01188318 0,07331007 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 0,01188318 0,07312258 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 0,01188318 0,07293604 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01188318 0,07275045 ! blastocyst development GO:0001824 49 26 1,000 0,01188318 0,07256581 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01188318 0,0723821 GO:0032943|mononuclear cell proliferation, ! monosaccharide catabolic process GO:0046365 115 76 2,000 0,0127548 0,07749507 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01278051 0,0774557 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01278051 0,07726109 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01278051 0,07706745 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01278051 0,07687478 ! male gonad development GO:0008584 44 27 1,000 0,01278051 0,07668307 ! response to toxin GO:0009636 47 27 1,000 0,01278051 0,07649232 ! primary neural tube formation GO:0014020 51 27 1,000 0,01278051 0,07630251 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01278051 0,07611364 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01321079 0,07848189 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,013676 0,08104545 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01370647 0,08102648 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01370647 0,08082789 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 0,01415044 0,08324197 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,01415044 0,08303894 ! response to metal ion GO:0010038 140 80 2,000 0,01463415 0,08566852 ! muscle cell differentiation GO:0042692 159 80 2,000 0,01463415 0,08546058 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01466067 0,08540815 ! catechol metabolic process GO:0009712 54 29 1,000 0,01466067 0,08520185 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 1,000 0,01466067 0,08499654 ! respiratory gaseous exchange GO:0007585 57 29 1,000 0,01466067 0,08479223 ! immune response-activating signal transduction GO:0002757 47 29 1,000 0,01466067 0,08458889 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01466067 0,08438652 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01466067 0,08418512 ! cell fate determination GO:0001709 60 29 1,000 0,01466067 0,08398468 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01466067 0,08378519 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01466067 0,08358665 ! tissue homeostasis GO:0001894 48 29 1,000 0,01466067 0,08338905 GO:0048871|multicellular organismal homeostasis, ! response to hypoxia GO:0001666 171 81 2,000 0,01512713 0,08583935 ! response to drug GO:0042493 143 82 2,000 0,01562942 0,08848091 ! response to nutrient GO:0007584 125 82 2,000 0,01562942 0,08827321 ! phenol metabolic process GO:0018958 55 30 1,000 0,0156427 0,08814129 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,0156427 0,08793536 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,0156427 0,08773038 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,0156427 0,08752635 ! response to heat GO:0009408 50 30 1,000 0,0156427 0,08732328 ! response to oxygen levels GO:0070482 176 83 2,000 0,01614103 0,08989654 ! ovulation cycle process GO:0022602 49 31 1,000 0,01665218 0,09252919 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 0,01665218 0,09231599 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01665218 0,09210377 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01665218 0,09189252 ! mesoderm formation GO:0001707 69 31 1,000 0,01665218 0,09168224 ! myeloid leukocyte activation GO:0002274 49 31 1,000 0,01665218 0,09147292 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01665218 0,09126455 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01719225 0,09401033 GO:0002696|positive regulation of leukocyte activation, ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01768872 0,09650579 ! spindle organization GO:0007051 46 32 1,000 0,01768872 0,09628745 ! metanephros development GO:0001656 74 32 1,000 0,01768872 0,0960701 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01768872 0,09585372 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01768872 0,09563832 ! ovulation cycle GO:0042698 51 32 1,000 0,01768872 0,09542389 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01768872 0,09521041 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01768872 0,09499789 ! gene silencing GO:0016458 65 32 1,000 0,01768872 0,09478631 ! alcohol catabolic process GO:0046164 130 86 2,000 0,01773189 0,09480652 ! response to inorganic substance GO:0010035 153 86 2,000 0,01773189 0,0945963 ! tube morphogenesis GO:0035239 176 86 2,000 0,01773189 0,09438702 ! regulation of protein transport GO:0051223 154 87 2,000 0,01828091 0,09709463 GO:0070201|regulation of establishment of protein localization, ! post-embryonic development GO:0009791 69 33 1,000 0,01875194 0,09937701 ! ceramide metabolic process GO:0006672 64 33 1,000 0,01875194 0,09915859 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01875194 0,09894114 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01875194 0,09872464 ! gland development GO:0048732 206 88 2,000 0,01883931 0,09896806 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01984146 0,10400555 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01984146 0,10377945 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01984146 0,10355433 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01984146 0,10333019 ! placenta development GO:0001890 53 34 1,000 0,01984146 0,10310701 ! ossification GO:0001503 188 90 2,000 0,01998428 0,10362538 ! bone development GO:0060348 189 91 2,000 0,02057087 0,10643764 ! regulation of muscle development GO:0048634 70 35 1,000 0,0209569 0,10820238 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,0209569 0,10797069 ! odontogenesis GO:0042476 66 35 1,000 0,0209569 0,10773998 ! female gonad development GO:0008585 58 35 1,000 0,0209569 0,10751026 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,0209569 0,10728151 ! neural tube formation GO:0001841 67 35 1,000 0,0209569 0,10705374 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02209791 0,11264314 ! sphingoid metabolic process GO:0046519 70 36 1,000 0,02209791 0,11240499 ! embryonic organ development GO:0048568 57 36 1,000 0,02209791 0,11216785 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02209791 0,11193171 ! regulation of T cell activation GO:0050863 158 94 2,000 0,02238707 0,1131582 ! meiosis I GO:0007127 65 37 1,000 0,02326409 0,11734468 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02326409 0,11709918 ! pigment metabolic process GO:0042440 80 37 1,000 0,02326409 0,11685472 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 2,000 0,02364493 0,11852023 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,02428798 0,12149037 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,02445511 0,12207258 GO:0006956|complement activation, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02445511 0,12181984 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,02445511 0,12156815 ! lipid homeostasis GO:0055088 67 38 1,000 0,02445511 0,12131749 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02445511 0,12106787 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02445511 0,12081927 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,02445511 0,12057169 ! Golgi vesicle transport GO:0048193 207 99 2,000 0,02560227 0,12596943 ! ear morphogenesis GO:0042471 60 39 1,000 0,02567058 0,12604779 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02567058 0,12579107 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,02567058 0,1255354 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02567058 0,12528076 ! RNA modification GO:0009451 57 39 1,000 0,02567058 0,12502716 ! cytokinesis GO:0000910 72 40 1,000 0,02691016 0,13079969 ! T cell differentiation GO:0030217 81 41 1,000 0,0281735 0,13666417 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,0281735 0,13638919 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,0281735 0,13611532 ! female gamete generation GO:0007292 61 41 1,000 0,0281735 0,13584254 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02946023 0,14176263 ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,02946023 0,14147968 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02946023 0,14119784 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,02946023 0,14091713 ! regulation of protein secretion GO:0050708 71 42 1,000 0,02946023 0,14063753 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,03077002 0,14659937 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,03077002 0,14630964 ! glucose transport GO:0015758 65 43 1,000 0,03077002 0,14602106 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,03077002 0,14573362 ! neural tube development GO:0021915 77 43 1,000 0,03077002 0,14544731 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,03077002 0,14516212 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03147391 0,14819221 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03147391 0,14790278 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03147391 0,14761447 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03147391 0,14732728 ! neuron fate determination GO:0048664 7 5 0,000 0,03147391 0,14704121 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03147391 0,14675624 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03147391 0,14647238 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03147391 0,14618962 ! polyol transport GO:0015791 12 5 0,000 0,03147391 0,14590794 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03147391 0,14562735 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03147391 0,14534783 ! response to superoxide GO:0000303 10 5 0,000 0,03147391 0,14506939 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03147391 0,14479201 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03147391 0,14451569 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03147391 0,14424042 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03147391 0,1439662 ! female meiosis GO:0007143 7 5 0,000 0,03147391 0,14369302 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03147391 0,14342087 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03147391 0,14314976 ! cobalt ion transport GO:0006824 11 5 0,000 0,03147391 0,14287966 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03147391 0,14261059 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03147391 0,14234252 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03147391 0,14207546 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03147391 0,1418094 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03147391 0,14154434 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03147391 0,14128026 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03147391 0,14101717 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03147391 0,14075506 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03147391 0,14049392 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03147391 0,14023374 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03147391 0,13997453 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03147391 0,13971628 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03147391 0,13945897 ! negative chemotaxis GO:0050919 14 5 0,000 0,03147391 0,13920261 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03147391 0,13894719 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03147391 0,13869271 ! behavioral response to pain GO:0048266 9 5 0,000 0,03147391 0,13843916 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03147391 0,13818654 ! Notch receptor processing GO:0007220 8 5 0,000 0,03147391 0,13793483 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03147391 0,13768404 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03147391 0,13743416 ! micturition GO:0060073 9 5 0,000 0,03147391 0,13718518 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03147391 0,13693711 ! copulation GO:0007620 9 5 0,000 0,03147391 0,13668993 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03147391 0,13644364 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03147391 0,13619824 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03147391 0,13595372 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03147391 0,13571007 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03147391 0,1354673 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03147391 0,1352254 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03147391 0,13498435 ! grooming behavior GO:0007625 6 5 0,000 0,03147391 0,13474417 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03147391 0,13450483 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03147391 0,13426635 ! response to protozoan GO:0001562 10 5 0,000 0,03147391 0,13402871 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,03147391 0,13379191 ! lymph vessel development GO:0001945 10 5 0,000 0,03147391 0,13355595 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03147391 0,13332081 ! endochondral ossification GO:0001958 16 5 0,000 0,03147391 0,1330865 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03147391 0,13285302 ! parathyroid gland development GO:0060017 13 5 0,000 0,03147391 0,13262035 ! anagen GO:0042640 6 5 0,000 0,03147391 0,1323885 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03147391 0,13215745 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03147391 0,13192721 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03147391 0,13169778 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03147391 0,13146913 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03147391 0,13124128 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03147391 0,13101422 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03147391 0,13078795 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03147391 0,13056245 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03147391 0,13033773 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03147391 0,13011378 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03147391 0,1298906 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03147391 0,12966819 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03147391 0,12944653 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03147391 0,12922563 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03147391 0,12900549 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03147391 0,12878609 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03147391 0,12856744 ! histidine catabolic process GO:0006548 6 5 0,000 0,03147391 0,12834953 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03147391 0,12813235 ! microvillus organization GO:0032528 7 5 0,000 0,03147391 0,12791591 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,03147391 0,1277002 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03147391 0,12748522 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03147391 0,12727096 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03147391 0,12705742 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03147391 0,12684459 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03147391 0,12663248 ! polyol catabolic process GO:0046174 7 5 0,000 0,03147391 0,12642107 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03147391 0,12621037 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03147391 0,12600037 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03147391 0,12579107 ! muscle cell migration GO:0014812 8 5 0,000 0,03147391 0,12558246 ! mitochondrial fission GO:0000266 8 5 0,000 0,03147391 0,12537454 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03147391 0,12516731 ! mRNA transcription GO:0009299 9 5 0,000 0,03147391 0,12496076 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03147391 0,12475489 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03147391 0,12454971 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03147391 0,12434519 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03147391 0,12414135 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03147391 0,12393817 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03147391 0,12373566 ! response to food GO:0032094 6 5 0,000 0,03147391 0,1235338 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03147391 0,12333261 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03147391 0,12313207 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03147391 0,12293218 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03147391 0,12273294 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03147391 0,12253434 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,03147391 0,12233638 ! forebrain neuron development GO:0021884 13 5 0,000 0,03147391 0,12213907 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03147391 0,12194239 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03147391 0,12174634 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03147391 0,12155092 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03147391 0,12135612 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03147391 0,12116195 ! folic acid transport GO:0015884 10 5 0,000 0,03147391 0,1209684 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03147391 0,12077547 ! basic amino acid transport GO:0015802 11 5 0,000 0,03147391 0,12058315 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03147391 0,12039145 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03147391 0,12020035 ! depyrimidination GO:0045008 10 5 0,000 0,03147391 0,12000986 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03147391 0,11981997 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03147391 0,11963068 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03147391 0,11944199 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03147391 0,11925389 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03147391 0,11906639 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03147391 0,11887947 ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03147391 0,11869314 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03147391 0,11850739 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03147391 0,11832222 ! response to arsenic GO:0046685 10 5 0,000 0,03147391 0,11813763 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03147391 0,11795362 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03147391 0,11777017 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03147391 0,1175873 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03147391 0,11740499 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03147391 0,11722325 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03147391 0,11704207 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03147391 0,11686145 ! decidualization GO:0046697 11 5 0,000 0,03147391 0,11668139 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03147391 0,11650188 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03147391 0,11632292 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03147391 0,11614451 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03147391 0,11596665 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03147391 0,11578933 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03147391 0,11561255 ! neural tube patterning GO:0021532 7 5 0,000 0,03147391 0,11543631 ! embryonic cleavage GO:0040016 6 5 0,000 0,03147391 0,11526061 ! peroxisome fission GO:0016559 5 5 0,000 0,03147391 0,11508544 ! histone demethylation GO:0016577 10 5 0,000 0,03147391 0,11491081 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03147391 0,1147367 ! mitotic recombination GO:0006312 9 5 0,000 0,03147391 0,11456312 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03147391 0,11439006 ! metaphase plate congression GO:0051310 7 5 0,000 0,03147391 0,11421753 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03147391 0,11404551 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03147391 0,11387402 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03147391 0,11370303 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03147391 0,11353257 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03147391 0,11336261 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03147391 0,11319316 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03147391 0,11302421 ! plasminogen activation GO:0031639 5 5 0,000 0,03147391 0,11285577 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03147391 0,11268783 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03147391 0,11252039 ! metaphase GO:0051323 8 5 0,000 0,03147391 0,11235344 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03147391 0,11218699 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03147391 0,11202104 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03147391 0,11185557 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03147391 0,11169059 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03147391 0,1115261 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03147391 0,11136209 ! response to redox state GO:0051775 5 5 0,000 0,03147391 0,11119856 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03147391 0,11103551 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03147391 0,11087294 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03147391 0,11071085 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03147391 0,11054923 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03147391 0,11038808 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03147391 0,1102274 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03147391 0,11006718 ! striatum development GO:0021756 9 5 0,000 0,03147391 0,10990743 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03147391 0,10974815 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03147391 0,10958932 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03147391 0,10943096 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03147391 0,10927305 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03147391 0,10911559 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03147391 0,10895859 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03147391 0,10880204 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03147391 0,10864594 ! neuroprotection GO:0043526 6 5 0,000 0,03147391 0,10849029 ! neural plate development GO:0001840 8 5 0,000 0,03147391 0,10833508 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03147391 0,10818032 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03147391 0,10802599 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03147391 0,10787211 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03147391 0,10771866 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03147391 0,10756566 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03147391 0,10741308 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03147391 0,10726094 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03147391 0,10710922 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03147391 0,10695794 ! spindle assembly GO:0051225 6 5 0,000 0,03147391 0,10680708 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03147391 0,10665665 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03147391 0,10650664 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 6 5 0,000 0,03147391 0,10635705 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03147391 0,10620788 ! organ regeneration GO:0031100 7 5 0,000 0,03147391 0,10605913 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03147391 0,1059108 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03147391 0,10576288 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03147391 0,10561537 ! hexose transport GO:0008645 67 44 1,000 0,03210253 0,10757478 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,03210253 0,10742516 ! B cell differentiation GO:0030183 107 44 1,000 0,03210253 0,10727596 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03345741 0,11164845 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,03345741 0,11149381 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,03345741 0,1113396 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,03483433 0,1157616 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,03483433 0,11560193 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,03483433 0,1154427 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03483433 0,11528391 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03623295 0,11974792 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03764942 0,12425858 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03764942 0,12408836 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03764942 0,12391861 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03764942 0,12374932 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03764942 0,12358049 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03764942 0,12341213 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03764942 0,12324422 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03764942 0,12307677 ! sleep GO:0030431 13 6 0,000 0,03764942 0,12290977 ! response to oxygen radical GO:0000305 11 6 0,000 0,03764942 0,12274323 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03764942 0,12257713 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03764942 0,12241149 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03764942 0,12224629 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03764942 0,12208154 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03764942 0,12191723 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03764942 0,12175336 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03764942 0,12158994 ! forebrain regionalization GO:0021871 8 6 0,000 0,03764942 0,12142695 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03764942 0,12126439 ! male meiosis GO:0007140 7 6 0,000 0,03764942 0,12110228 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03764942 0,12094059 ! response to zinc ion GO:0010043 9 6 0,000 0,03764942 0,12077934 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03764942 0,12061851 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03764942 0,12045811 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03764942 0,12029814 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03764942 0,1201386 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03764942 0,11997947 ! malate metabolic process GO:0006108 11 6 0,000 0,03764942 0,11982077 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03764942 0,11966249 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03764942 0,11950462 ! protein refolding GO:0042026 15 6 0,000 0,03764942 0,11934717 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03764942 0,11919013 ! opsonization GO:0008228 8 6 0,000 0,03764942 0,11903351 ! mating behavior GO:0007617 7 6 0,000 0,03764942 0,1188773 ! neuron remodeling GO:0016322 15 6 0,000 0,03764942 0,1187215 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03764942 0,1185661 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03764942 0,11841111 ! equilibrioception GO:0050957 14 6 0,000 0,03764942 0,11825653 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03764942 0,11810235 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03764942 0,11794857 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03764942 0,11779519 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03764942 0,11764221 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03764942 0,11748963 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03764942 0,11733744 ! toxin metabolic process GO:0009404 11 6 0,000 0,03764942 0,11718564 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03764942 0,11703424 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03764942 0,11688323 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03764942 0,11673261 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03764942 0,11658237 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03764942 0,11643252 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03764942 0,11628306 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03764942 0,11613398 ! thymic T cell selection GO:0045061 12 6 0,000 0,03764942 0,11598528 ! protein lipoylation GO:0009249 10 6 0,000 0,03764942 0,11583696 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03764942 0,11568902 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03764942 0,11554146 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03764942 0,11539427 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03764942 0,11524746 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03764942 0,11510102 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,03764942 0,11495495 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03764942 0,11480926 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03764942 0,11466393 ! hyperosmotic response GO:0006972 9 6 0,000 0,03764942 0,11451897 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03764942 0,11437437 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03764942 0,11423014 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03764942 0,11408628 ! urea metabolic process GO:0019627 7 6 0,000 0,03764942 0,11394277 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03764942 0,11379963 ! neutrophil activation GO:0042119 8 6 0,000 0,03764942 0,11365684 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03764942 0,11351441 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03764942 0,11337234 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03764942 0,11323063 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03764942 0,11308927 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03764942 0,11294826 ! neuron apoptosis GO:0051402 9 6 0,000 0,03764942 0,1128076 ! nucleoside salvage GO:0043174 9 6 0,000 0,03764942 0,11266729 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03764942 0,11252733 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03764942 0,11238772 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03764942 0,11224845 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03764942 0,11210953 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03764942 0,11197095 ! carnitine transport GO:0015879 10 6 0,000 0,03764942 0,11183272 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03764942 0,11169482 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03764942 0,11155727 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03764942 0,11142005 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03764942 0,11128317 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03764942 0,11114663 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03764942 0,11101042 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03764942 0,11087454 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03764942 0,110739 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03764942 0,11060379 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03764942 0,11046891 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 11 6 0,000 0,03764942 0,11033435 ! astrocyte development GO:0014002 15 6 0,000 0,03764942 0,11020012 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03764942 0,11006622 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03764942 0,10993265 ! interaction with symbiont GO:0051702 13 6 0,000 0,03764942 0,1097994 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03764942 0,10966647 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03764942 0,10953386 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03764942 0,10940157 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03764942 0,1092696 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03764942 0,10913795 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03764942 0,10900662 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03764942 0,1088756 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03764942 0,1087449 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03764942 0,10861451 ! hair follicle maturation GO:0048820 7 6 0,000 0,03764942 0,10848443 ! Schwann cell development GO:0014044 15 6 0,000 0,03764942 0,10835467 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03764942 0,10822521 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03764942 0,10809607 ! subpallium development GO:0021544 10 6 0,000 0,03764942 0,10796723 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03764942 0,10783869 ! histone ubiquitination GO:0016574 8 6 0,000 0,03764942 0,10771047 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03764942 0,10758254 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03764942 0,10745493 ! G2 phase GO:0051319 16 6 0,000 0,03764942 0,10732761 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03764942 0,10720059 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03764942 0,10707388 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03764942 0,10694746 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03764942 0,10682135 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03764942 0,10669553 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03764942 0,10657 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03764942 0,10644477 ! receptor internalization GO:0031623 10 6 0,000 0,03764942 0,10631984 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03764942 0,1061952 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03764942 0,10607085 ! protein deubiquitination GO:0016579 14 6 0,000 0,03764942 0,10594679 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03764942 0,10582302 ! protein destabilization GO:0031648 9 6 0,000 0,03764942 0,10569954 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03764942 0,10557634 ! regulation of viral transcription GO:0046782 10 6 0,000 0,03764942 0,10545344 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03764942 0,10533082 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03764942 0,10520848 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03764942 0,10508643 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03764942 0,10496466 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03764942 0,10484317 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03764942 0,10472197 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03764942 0,10460104 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03764942 0,1044804 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03764942 0,10436003 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03764942 0,10423993 ! catecholamine transport GO:0051937 9 6 0,000 0,03764942 0,10412012 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03764942 0,10400058 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03764942 0,10388131 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03764942 0,10376232 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03764942 0,1036436 ! maternal placenta development GO:0001893 12 6 0,000 0,03764942 0,10352515 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03764942 0,10340697 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03764942 0,10328906 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03764942 0,10317142 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03764942 0,10305404 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03764942 0,10293693 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03764942 0,10282009 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03764942 0,10270352 ! cellular component disassembly GO:0022411 86 48 1,000 0,03765295 0,10259683 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03765295 0,10248077 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03765295 0,10236498 ! activation of caspase activity GO:0006919 84 48 1,000 0,03765295 0,10224944 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,03765295 0,10213417 ! response to temperature stimulus GO:0009266 76 49 1,000 0,039094 0,10592361 ! endocrine system development GO:0035270 104 49 1,000 0,039094 0,10580446 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,039094 0,10568558 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,039094 0,10556697 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,04055578 0,10939147 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,04055578 0,10926898 ! positive regulation of binding GO:0051099 78 51 1,000 0,04203796 0,11313571 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,04203796 0,1130093 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,04203796 0,11288317 ! vesicle organization GO:0016050 107 51 1,000 0,04203796 0,11275733 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04354023 0,11665677 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,04354023 0,11652701 ! synapse organization GO:0050808 85 52 1,000 0,04354023 0,11639754 ! tRNA transcription GO:0009304 14 7 0,000 0,04378576 0,11692401 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04378576 0,11679438 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04378576 0,11666504 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04378576 0,11653599 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04378576 0,11640722 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04378576 0,11627874 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04378576 0,11615053 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04378576 0,11602262 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04378576 0,11589498 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04378576 0,11576762 ! prostate gland development GO:0030850 13 7 0,000 0,04378576 0,11564054 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04378576 0,11551374 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04378576 0,11538722 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04378576 0,11526098 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04378576 0,11513501 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04378576 0,11500932 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04378576 0,1148839 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04378576 0,11475875 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04378576 0,11463388 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04378576 0,11450928 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04378576 0,11438495 ! glycolipid transport GO:0046836 10 7 0,000 0,04378576 0,11426088 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04378576 0,11413709 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04378576 0,11401357 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04378576 0,11389031 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04378576 0,11376732 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04378576 0,11364459 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04378576 0,11352213 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04378576 0,11339993 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04378576 0,11327799 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04378576 0,11315632 ! mRNA stabilization GO:0048255 18 7 0,000 0,04378576 0,11303491 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04378576 0,11291376 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04378576 0,11279286 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04378576 0,11267223 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04378576 0,11255185 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04378576 0,11243173 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04378576 0,11231187 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04378576 0,11219226 ! rhythmic behavior GO:0007622 15 7 0,000 0,04378576 0,11207291 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04378576 0,11195381 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04378576 0,11183496 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04378576 0,11171637 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04378576 0,11159802 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04378576 0,11147993 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04378576 0,11136209 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04378576 0,11124449 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04378576 0,11112715 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04378576 0,11101005 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04378576 0,11089319 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04378576 0,11077659 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04378576 0,11066023 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04378576 0,11054411 ! spinal cord patterning GO:0021511 13 7 0,000 0,04378576 0,11042823 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04378576 0,1103126 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04378576 0,11019721 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04378576 0,11008206 ! adrenal gland development GO:0030325 17 7 0,000 0,04378576 0,10996716 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04378576 0,10985249 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04378576 0,10973806 ! ovulation GO:0030728 9 7 0,000 0,04378576 0,10962387 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04378576 0,10950991 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04378576 0,10939619 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04378576 0,10928271 ! microtubule nucleation GO:0007020 20 7 0,000 0,04378576 0,10916947 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04378576 0,10905645 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04378576 0,10894368 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04378576 0,10883113 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04378576 0,10871882 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04378576 0,10860674 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04378576 0,10849489 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04378576 0,10838327 ! galactose metabolic process GO:0006012 13 7 0,000 0,04378576 0,10827188 ! vesicle fusion GO:0006906 17 7 0,000 0,04378576 0,10816071 ! response to dietary excess GO:0002021 8 7 0,000 0,04378576 0,10804978 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04378576 0,10793907 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04378576 0,10782859 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04378576 0,10771834 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04378576 0,10760831 ! purine salvage GO:0043101 10 7 0,000 0,04378576 0,1074985 ! nucleoside transport GO:0015858 8 7 0,000 0,04378576 0,10738892 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04378576 0,10727957 ! parturition GO:0007567 14 7 0,000 0,04378576 0,10717043 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04378576 0,10706152 ! rRNA modification GO:0000154 14 7 0,000 0,04378576 0,10695283 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04378576 0,10684436 ! spindle checkpoint GO:0031577 15 7 0,000 0,04378576 0,1067361 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04378576 0,10662807 ! macrophage differentiation GO:0030225 11 7 0,000 0,04378576 0,10652026 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04378576 0,10641266 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04378576 0,10630528 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04378576 0,10619812 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04378576 0,10609117 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04378576 0,10598444 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04378576 0,10587792 ! fibrinolysis GO:0042730 10 7 0,000 0,04378576 0,10577162 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04378576 0,10566553 ! eating behavior GO:0042755 7 7 0,000 0,04378576 0,10555965 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04378576 0,10545399 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04378576 0,10534853 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04378576 0,10524329 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04378576 0,10513826 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04378576 0,10503343 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04378576 0,10492882 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04378576 0,10482441 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04378576 0,10472021 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04378576 0,10461622 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04378576 0,10451244 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04378576 0,10440886 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04378576 0,10430548 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04378576 0,10420231 ! regulation of meiosis GO:0040020 12 7 0,000 0,04378576 0,10409934 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04378576 0,10399658 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04378576 0,10389402 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04378576 0,10379166 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04378576 0,1036895 ! transcription termination GO:0006353 13 7 0,000 0,04378576 0,10358755 ! response to tumor cell GO:0002347 13 7 0,000 0,04378576 0,10348579 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04378576 0,10338423 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04378576 0,10328288 ! anaphase GO:0051322 17 7 0,000 0,04378576 0,10318172 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04378576 0,10308076 ! axonal fasciculation GO:0007413 18 7 0,000 0,04378576 0,10297999 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04378576 0,10287943 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04378576 0,10277906 ! diuresis GO:0030146 12 7 0,000 0,04378576 0,10267888 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04378576 0,1025789 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04378576 0,10247912 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04378576 0,10237953 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04378576 0,10228013 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04378576 0,10218093 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04378576 0,10208191 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04378576 0,10198309 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04378576 0,10188446 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04378576 0,10178602 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04378576 0,10168777 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04378576 0,10158972 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04378576 0,10149184 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04378576 0,10139416 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04378576 0,10129667 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04378576 0,10119936 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04378576 0,10110224 ! adult feeding behavior GO:0008343 9 7 0,000 0,04378576 0,10100531 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04378576 0,10090856 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04378576 0,10081199 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04378576 0,10071562 ! muscle adaptation GO:0043500 14 7 0,000 0,04378576 0,10061942 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04378576 0,10052341 ! retina homeostasis GO:0001895 12 7 0,000 0,04378576 0,10042758 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04378576 0,10033194 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04378576 0,10023647 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04378576 0,10014119 ! protein prenylation GO:0018342 18 7 0,000 0,04378576 0,10004609 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04378576 0,09995117 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04378576 0,09985643 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04378576 0,09976187 ! cell maturation GO:0048469 100 53 1,000 0,04506227 0,10257316 ! response to UV GO:0009411 104 53 1,000 0,04506227 0,10247621 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,04506227 0,10237944 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,04660379 0,1057818 ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,04660379 0,1056821 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,04660379 0,10558259 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04816446 0,10901569 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 1,000 0,04816446 0,10891324 ! gastrulation GO:0007369 112 55 1,000 0,04816446 0,10881097 ! heart morphogenesis GO:0003007 97 55 1,000 0,04816446 0,1087089 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,04816446 0,10860701 ! regulation of DNA replication GO:0006275 101 56 1,000 0,04974398 0,11206369 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04988317 0,11227214 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04988317 0,11216721 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04988317 0,11206248 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04988317 0,11195794 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04988317 0,1118536 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04988317 0,11174945 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04988317 0,1116455 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04988317 0,11154174 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04988317 0,11143817 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04988317 0,1113348 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04988317 0,11123162 ! meiotic prophase I GO:0007128 13 8 0,000 0,04988317 0,11112862 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04988317 0,11102582 ! oligopeptide transport GO:0006857 15 8 0,000 0,04988317 0,11092321 ! signal peptide processing GO:0006465 12 8 0,000 0,04988317 0,11082079 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04988317 0,11071855 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04988317 0,11061651 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04988317 0,11051465 ! succinate metabolic process GO:0006105 14 8 0,000 0,04988317 0,11041298 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04988317 0,1103115 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04988317 0,1102102 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04988317 0,11010909 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04988317 0,11000817 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04988317 0,10990743 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04988317 0,10980687 ! reflex GO:0060004 16 8 0,000 0,04988317 0,1097065 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04988317 0,10960631 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04988317 0,10950631 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04988317 0,10940648 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04988317 0,10930684 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04988317 0,10920738 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04988317 0,1091081 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04988317 0,109009 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04988317 0,10891008 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04988317 0,10881134 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04988317 0,10871278 ! histidine metabolic process GO:0006547 16 8 0,000 0,04988317 0,1086144 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04988317 0,1085162 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04988317 0,10841817 ! glycine catabolic process GO:0006546 13 8 0,000 0,04988317 0,10832032 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04988317 0,10822264 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04988317 0,10812515 GO:0006559|L-phenylalanine catabolic process, ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04988317 0,10802782 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04988317 0,10793068 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04988317 0,1078337 ! macrophage activation GO:0042116 12 8 0,000 0,04988317 0,10773691 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04988317 0,10764028 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04988317 0,10754383 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04988317 0,10744755 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04988317 0,10735144 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04988317 0,10725551 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04988317 0,10715974 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04988317 0,10706415 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04988317 0,10696873 ! osteoblast development GO:0002076 16 8 0,000 0,04988317 0,10687348 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04988317 0,10677839 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04988317 0,10668348 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04988317 0,10658873 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04988317 0,10649416 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04988317 0,10639975 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04988317 0,1063055 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04988317 0,10621143 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04988317 0,10611752 ! intermediate filament organization GO:0045109 12 8 0,000 0,04988317 0,10602377 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04988317 0,1059302 ! cellular extravasation GO:0045123 12 8 0,000 0,04988317 0,10583678 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04988317 0,10574354 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04988317 0,10565045 ! response to antibiotic GO:0046677 11 8 0,000 0,04988317 0,10555753 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04988317 0,10546477 ! DNA topological change GO:0006265 12 8 0,000 0,04988317 0,10537218 ! response to tropane GO:0014073 15 8 0,000 0,04988317 0,10527975 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,04988317 0,10518748 ! melanosome transport GO:0032402 13 8 0,000 0,04988317 0,10509537 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,04988317 0,10500342 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04988317 0,10491164 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04988317 0,10482001 ! mast cell activation GO:0045576 14 8 0,000 0,04988317 0,10472855 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04988317 0,10463724 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04988317 0,10454609 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04988317 0,1044551 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04988317 0,10436427 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04988317 0,1042736 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04988317 0,10418308 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04988317 0,10409273 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04988317 0,10400252 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04988317 0,10391248 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04988317 0,10382259 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04988317 0,10373285 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04988317 0,10364328 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04988317 0,10355385 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04988317 0,10346458 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04988317 0,10337546 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04988317 0,1032865 ! hormone catabolic process GO:0042447 17 8 0,000 0,04988317 0,10319769 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04988317 0,10310903 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04988317 0,10302053 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04988317 0,10293217 ! ATP catabolic process GO:0006200 11 8 0,000 0,04988317 0,10284397 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04988317 0,10275592 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04988317 0,10266802 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04988317 0,10258027 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04988317 0,10249267 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04988317 0,10240522 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04988317 0,10231791 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04988317 0,10223076 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04988317 0,10214376 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04988317 0,1020569 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04988317 0,10197019 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04988317 0,10188363 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04988317 0,10179721 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04988317 0,10171094 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04988317 0,10162482 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04988317 0,10153884 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04988317 0,10145301 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04988317 0,10136732 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,05134206 0,10424388 ! adult behavior GO:0030534 99 58 1,000 0,0529584 0,107435 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,0545927 0,11065714 ! DNA catabolic process GO:0006308 86 59 1,000 0,0545927 0,11056399 ! establishment of organelle localization GO:0051656 109 59 1,000 0,0545927 0,110471 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05594191 0,11310607 ! axon extension GO:0048675 15 9 0,000 0,05594191 0,11301111 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05594191 0,1129163 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05594191 0,11282165 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05594191 0,11272716 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05594191 0,11263283 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05594191 0,11253865 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05594191 0,11244463 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05594191 0,11235077 ! phosphate transport GO:0006817 19 9 0,000 0,05594191 0,11225707 ! reproductive behavior GO:0019098 19 9 0,000 0,05594191 0,11216352 ! RNA methylation GO:0001510 15 9 0,000 0,05594191 0,11207013 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05594191 0,11197689 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05594191 0,11188381 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05594191 0,11179089 ! artery development GO:0060840 24 9 0,000 0,05594191 0,11169811 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 0,000 0,05594191 0,1116055 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05594191 0,11151303 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05594191 0,11142072 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05594191 0,11132856 ! chemosensory behavior GO:0007635 20 9 0,000 0,05594191 0,11123655 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05594191 0,1111447 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05594191 0,11105299 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05594191 0,11096144 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05594191 0,11087004 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05594191 0,11077879 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05594191 0,11068769 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05594191 0,11059674 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05594191 0,11050593 ! protein targeting to ER GO:0045047 22 9 0,000 0,05594191 0,11041528 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05594191 0,11032478 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05594191 0,11023442 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,05594191 0,11014421 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05594191 0,11005415 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05594191 0,10996424 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05594191 0,10987447 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05594191 0,10978485 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05594191 0,10969538 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05594191 0,10960605 ! mannose metabolic process GO:0006013 13 9 0,000 0,05594191 0,10951687 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05594191 0,10942783 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05594191 0,10933893 ! receptor clustering GO:0043113 18 9 0,000 0,05594191 0,10925018 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05594191 0,10916158 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05594191 0,10907312 ! ruffle organization GO:0031529 15 9 0,000 0,05594191 0,1089848 ! retinol metabolic process GO:0042572 18 9 0,000 0,05594191 0,10889662 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05594191 0,10880859 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05594191 0,1087207 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05594191 0,10863295 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05594191 0,10854534 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,05594191 0,10845788 ! protein heterooligomerization GO:0051291 16 9 0,000 0,05594191 0,10837055 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05594191 0,10828337 ! segment specification GO:0007379 13 9 0,000 0,05594191 0,10819632 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05594191 0,10810942 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05594191 0,10802265 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05594191 0,10793603 ! response to amine stimulus GO:0014075 13 9 0,000 0,05594191 0,10784954 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05594191 0,10776319 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05594191 0,10767698 ! erythrocyte development GO:0048821 15 9 0,000 0,05594191 0,10759091 ! gas homeostasis GO:0033483 16 9 0,000 0,05594191 0,10750497 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05594191 0,10741918 ! renal water homeostasis GO:0003091 14 9 0,000 0,05594191 0,10733351 ! postreplication repair GO:0006301 22 9 0,000 0,05594191 0,10724799 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05594191 0,1071626 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05594191 0,10707735 ! icosanoid secretion GO:0032309 15 9 0,000 0,05594191 0,10699223 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05594191 0,10690725 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05594191 0,1068224 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05594191 0,10673769 ! regulation of cell division GO:0051302 15 9 0,000 0,05594191 0,10665311 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05594191 0,10656867 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05594191 0,10648436 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05594191 0,10640018 ! sterol catabolic process GO:0016127 11 9 0,000 0,05594191 0,10631614 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05594191 0,10623222 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05594191 0,10614844 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05594191 0,1060648 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05594191 0,10598128 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05594191 0,1058979 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05594191 0,10581464 GO:0050879|multicellular organismal movement, ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05594191 0,10573152 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05594191 0,10564853 ! purine base metabolic process GO:0006144 21 9 0,000 0,05594191 0,10556567 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05594191 0,10548294 ! pigment granule transport GO:0051904 17 9 0,000 0,05594191 0,10540033 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05594191 0,10531786 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05594191 0,10523552 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05594191 0,1051533 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05594191 0,10507122 ! mitochondrion localization GO:0051646 15 9 0,000 0,05594191 0,10498926 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,05624466 0,10547518 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,05624466 0,10539303 ! kidney development GO:0001822 122 60 1,000 0,05624466 0,10531101 ! mesoderm development GO:0007498 119 61 1,000 0,05791401 0,10835233 ! sphingolipid metabolic process GO:0006665 107 61 1,000 0,05791401 0,10826814 ! gonad development GO:0008406 98 62 1,000 0,05960045 0,11133437 ! detection of external stimulus GO:0009581 91 63 1,000 0,06130369 0,11442722 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,06196221 0,11556672 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06196221 0,1154772 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06196221 0,11538782 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,06196221 0,11529858 ! synapsis GO:0007129 13 10 0,000 0,06196221 0,11520948 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06196221 0,11512051 ! N-glycan processing GO:0006491 20 10 0,000 0,06196221 0,11503169 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06196221 0,114943 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06196221 0,11485444 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06196221 0,11476602 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06196221 0,11467774 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06196221 0,1145896 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06196221 0,11450159 ! androgen metabolic process GO:0008209 17 10 0,000 0,06196221 0,11441371 ! phospholipid efflux GO:0033700 16 10 0,000 0,06196221 0,11432597 ! lung alveolus development GO:0048286 26 10 0,000 0,06196221 0,11423836 ! pathogenesis GO:0009405 13 10 0,000 0,06196221 0,11415089 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06196221 0,11406355 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06196221 0,11397635 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06196221 0,11388928 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06196221 0,11380234 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06196221 0,11371553 ! endoderm development GO:0007492 16 10 0,000 0,06196221 0,11362886 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06196221 0,11354232 ! arginine catabolic process GO:0006527 13 10 0,000 0,06196221 0,11345591 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06196221 0,11336963 ! proline metabolic process GO:0006560 13 10 0,000 0,06196221 0,11328348 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06196221 0,11319747 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06196221 0,11311158 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06196221 0,11302583 ! V(D)J recombination GO:0033151 28 10 0,000 0,06196221 0,1129402 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06196221 0,11285471 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06196221 0,11276934 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06196221 0,1126841 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06196221 0,11259899 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06196221 0,11251401 ! multicellular organism growth GO:0035264 18 10 0,000 0,06196221 0,11242916 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06196221 0,11234444 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06196221 0,11225984 ! epithelial cell development GO:0002064 20 10 0,000 0,06196221 0,11217537 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06196221 0,11209103 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06196221 0,11200681 ! macroautophagy GO:0016236 17 10 0,000 0,06196221 0,11192272 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06196221 0,11183876 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06196221 0,11175492 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06196221 0,11167121 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06196221 0,11158762 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,06196221 0,11150416 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06196221 0,11142083 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06196221 0,11133761 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06196221 0,11125453 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06196221 0,11117156 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06196221 0,11108872 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06196221 0,11100601 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06196221 0,11092341 ! response to dsRNA GO:0043331 20 10 0,000 0,06196221 0,11084094 ! DNA ligation GO:0006266 19 10 0,000 0,06196221 0,11075859 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06196221 0,11067637 ! melanosome localization GO:0032400 16 10 0,000 0,06196221 0,11059426 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06196221 0,11051228 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06196221 0,11043042 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06196221 0,11034868 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06196221 0,11026706 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06196221 0,11018556 ! mRNA cleavage GO:0006379 17 10 0,000 0,06196221 0,11010418 ! protein sumoylation GO:0016925 15 10 0,000 0,06196221 0,11002293 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06196221 0,10994179 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06196221 0,10986077 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06196221 0,10977987 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06196221 0,10969909 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06196221 0,10961843 ! prophase GO:0051324 15 10 0,000 0,06196221 0,10953789 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06196221 0,10945746 ! apical protein localization GO:0045176 15 10 0,000 0,06196221 0,10937716 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06196221 0,10929697 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06196221 0,1092169 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,06196221 0,10913694 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06196221 0,10905711 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06196221 0,10897739 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06196221 0,10889778 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06196221 0,1088183 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06196221 0,10873893 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06196221 0,10865967 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06196221 0,10858053 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,06196221 0,1085015 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,06196221 0,10842259 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06196221 0,1083438 ! blastocyst formation GO:0001825 17 10 0,000 0,06196221 0,10826512 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06196221 0,10818655 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06196221 0,1081081 ! activation of innate immune response GO:0002218 12 10 0,000 0,06196221 0,10802976 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06196221 0,10795153 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06196221 0,10787342 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06196221 0,10779542 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06196221 0,10771753 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06196221 0,10763976 ! localization within membrane GO:0051668 20 10 0,000 0,06196221 0,1075621 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,06302347 0,10932551 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,06302347 0,10924674 GO:0048609|reproductive process in a multicellular organism, ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,06475951 0,11217522 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,06475951 0,11209451 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,06475951 0,11201393 ! secondary metabolic process GO:0019748 116 66 1,000 0,06651152 0,11496172 ! developmental maturation GO:0021700 116 66 1,000 0,06651152 0,11487919 ! cell projection assembly GO:0030031 120 66 1,000 0,06651152 0,11479678 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06794431 0,11718567 ! respiratory burst GO:0045730 17 11 0,000 0,06794431 0,11710173 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06794431 0,1170179 ! neuron fate specification GO:0048665 17 11 0,000 0,06794431 0,1169342 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06794431 0,11685062 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06794431 0,11676715 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06794431 0,11668381 ! thyroid gland development GO:0030878 26 11 0,000 0,06794431 0,11660058 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,06794431 0,11651747 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06794431 0,11643448 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06794431 0,11635161 ! response to pain GO:0048265 24 11 0,000 0,06794431 0,11626886 ! T cell proliferation GO:0042098 26 11 0,000 0,06794431 0,11618622 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06794431 0,1161037 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06794431 0,1160213 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06794431 0,11593902 ! bone resorption GO:0045453 16 11 0,000 0,06794431 0,11585685 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06794431 0,1157748 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06794431 0,11569286 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06794431 0,11561104 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06794431 0,11552934 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06794431 0,11544775 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06794431 0,11536628 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06794431 0,11528492 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06794431 0,11520367 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06794431 0,11512254 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06794431 0,11504153 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06794431 0,11496063 ! lipid digestion GO:0044241 18 11 0,000 0,06794431 0,11487984 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06794431 0,11479917 ! UV protection GO:0009650 19 11 0,000 0,06794431 0,11471861 ! adult heart development GO:0007512 14 11 0,000 0,06794431 0,11463816 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06794431 0,11455782 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06794431 0,1144776 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06794431 0,11439749 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06794431 0,11431749 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06794431 0,1142376 ! pigment granule localization GO:0051875 20 11 0,000 0,06794431 0,11415783 ! vasoconstriction GO:0042310 18 11 0,000 0,06794431 0,11407817 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06794431 0,11399861 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06794431 0,11391917 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06794431 0,11383984 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06794431 0,11376062 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06794431 0,11368151 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06794431 0,11360251 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06794431 0,11352362 ! zymogen activation GO:0031638 15 11 0,000 0,06794431 0,11344484 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06794431 0,11336617 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06794431 0,1132876 ! nucleosome positioning GO:0016584 15 11 0,000 0,06794431 0,11320915 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06794431 0,1131308 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06794431 0,11305257 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06794431 0,11297444 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06794431 0,11289642 ! acid secretion GO:0046717 18 11 0,000 0,06794431 0,1128185 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06794431 0,1127407 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06794431 0,112663 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06794431 0,11258541 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06794431 0,11250792 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06794431 0,11243055 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06794431 0,11235327 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06794431 0,11227611 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06794431 0,11219905 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06794431 0,11212209 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06794431 0,11204525 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06794431 0,1119685 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06794431 0,11189186 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06794431 0,11181533 ! defense response to fungus GO:0050832 13 11 0,000 0,06794431 0,1117389 ! developmental induction GO:0031128 19 11 0,000 0,06794431 0,11166258 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06794431 0,11158636 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06794431 0,11151024 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06794431 0,11143423 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06794431 0,11135832 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06794431 0,11128251 ! nucleus localization GO:0051647 19 11 0,000 0,06794431 0,11120681 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06794431 0,11113121 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,06827923 0,11160315 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,06827923 0,11152739 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06827923 0,11145172 ! chromosome segregation GO:0007059 113 67 1,000 0,06827923 0,11137616 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,07006239 0,11420739 ! membrane lipid metabolic process GO:0006643 117 68 1,000 0,07006239 0,11413007 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,07006239 0,11405285 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,07186071 0,1169012 ! urogenital system development GO:0001655 137 69 1,000 0,07186071 0,11682222 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,07186071 0,11674334 ! antigen processing and presentation GO:0019882 104 69 1,000 0,07186071 0,11666456 ! appendage morphogenesis GO:0035107 135 70 1,000 0,07367395 0,11952766 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,07367395 0,11944711 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07388846 0,11971424 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07388846 0,11963368 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07388846 0,11955323 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07388846 0,11947288 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07388846 0,11939264 ! virus-host interaction GO:0019048 29 12 0,000 0,07388846 0,11931251 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,07388846 0,11923249 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07388846 0,11915258 ! cartilage condensation GO:0001502 20 12 0,000 0,07388846 0,11907277 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,07388846 0,11899307 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,07388846 0,11891348 ! protein complex disassembly GO:0043241 27 12 0,000 0,07388846 0,11883399 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07388846 0,11875461 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07388846 0,11867533 ! hippocampus development GO:0021766 26 12 0,000 0,07388846 0,11859616 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,07388846 0,1185171 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07388846 0,11843814 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07388846 0,11835929 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07388846 0,11828054 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07388846 0,11820189 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07388846 0,11812335 ! drug transport GO:0015893 16 12 0,000 0,07388846 0,11804492 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07388846 0,11796659 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07388846 0,11788836 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07388846 0,11781024 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07388846 0,11773222 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07388846 0,1176543 ! forebrain cell migration GO:0021885 21 12 0,000 0,07388846 0,11757649 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07388846 0,11749877 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07388846 0,11742117 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07388846 0,11734366 ! entry into host cell GO:0030260 32 12 0,000 0,07388846 0,11726626 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,07388846 0,11718896 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07388846 0,11711176 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07388846 0,11703466 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07388846 0,11695766 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07388846 0,11688077 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07388846 0,11680397 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07388846 0,11672728 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07388846 0,11665069 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07388846 0,11657419 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07388846 0,1164978 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07388846 0,11642151 ! cranial nerve development GO:0021545 20 12 0,000 0,07388846 0,11634532 ! fucose catabolic process GO:0019317 22 12 0,000 0,07388846 0,11626923 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07388846 0,11619323 ! histone acetylation GO:0016573 26 12 0,000 0,07388846 0,11611734 ! histone methylation GO:0016571 26 12 0,000 0,07388846 0,11604154 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07388846 0,11596585 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,07388846 0,11589025 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07388846 0,11581475 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07388846 0,11573935 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07388846 0,11566405 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07388846 0,11558885 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07388846 0,11551374 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,07388846 0,11543873 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07388846 0,11536382 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07388846 0,11528901 ! response to cold GO:0009409 17 12 0,000 0,07388846 0,11521429 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07388846 0,11513967 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07388846 0,11506514 ! reproductive structure development GO:0048608 113 71 1,000 0,07550183 0,11750155 ! appendage development GO:0048736 136 71 1,000 0,07550183 0,1174256 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 1,000 0,07550183 0,11734974 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,07550183 0,11727398 ! regulation of immune effector process GO:0002697 137 71 1,000 0,07550183 0,11719832 ! acute inflammatory response GO:0002526 113 72 1,000 0,0773441 0,11998059 ! regulation of caspase activity GO:0043281 122 72 1,000 0,0773441 0,11990328 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,0773441 0,11982608 ! carbohydrate transport GO:0008643 110 72 1,000 0,0773441 0,11974897 ! regulation of blood pressure GO:0008217 125 73 1,000 0,0792005 0,12254431 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07979491 0,12338467 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07979491 0,12330542 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07979491 0,12322628 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07979491 0,12314724 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07979491 0,1230683 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07979491 0,12298946 ! lipid localization GO:0010876 28 13 0,000 0,07979491 0,12291072 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07979491 0,12283208 ! organelle fusion GO:0048284 32 13 0,000 0,07979491 0,12275354 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07979491 0,12267511 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07979491 0,12259677 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07979491 0,12251853 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07979491 0,1224404 ! methionine metabolic process GO:0006555 27 13 0,000 0,07979491 0,12236236 ! plasma membrane organization GO:0007009 24 13 0,000 0,07979491 0,12228442 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07979491 0,12220658 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07979491 0,12212884 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07979491 0,1220512 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07979491 0,12197366 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07979491 0,12189622 ! response to X-ray GO:0010165 25 13 0,000 0,07979491 0,12181887 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07979491 0,12174163 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07979491 0,12166448 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07979491 0,12158743 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07979491 0,12151047 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07979491 0,12143361 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07979491 0,12135685 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07979491 0,12128019 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07979491 0,12120363 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07979491 0,12112716 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07979491 0,12105078 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07979491 0,12097451 ! ribosome assembly GO:0042255 17 13 0,000 0,07979491 0,12089833 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,07979491 0,12082224 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07979491 0,12074625 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07979491 0,12067036 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07979491 0,12059456 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07979491 0,12051886 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07979491 0,12044325 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07979491 0,12036774 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07979491 0,12029232 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07979491 0,120217 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07979491 0,12014177 ! embryonic placenta development GO:0001892 23 13 0,000 0,07979491 0,12006663 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07979491 0,11999159 ! insulin secretion GO:0030073 23 13 0,000 0,07979491 0,11991664 ! actin filament polymerization GO:0030041 24 13 0,000 0,07979491 0,11984179 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07979491 0,11976703 ! acrosome reaction GO:0007340 18 13 0,000 0,07979491 0,11969236 ! neurotransmitter transport GO:0006836 123 74 1,000 0,08107078 0,1215304 ! meiosis GO:0007126 121 74 1,000 0,08107078 0,12145473 GO:0051327|M phase of meiotic cell cycle, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,08107078 0,12137915 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,08107078 0,12130367 ! eye development GO:0001654 143 74 1,000 0,08107078 0,12122828 ! organelle localization GO:0051640 136 74 1,000 0,08107078 0,12115298 ! meiotic cell cycle GO:0051321 122 75 1,000 0,08295469 0,12389136 ! rhythmic process GO:0048511 128 75 1,000 0,08295469 0,12381451 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,08295469 0,12373775 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,08485199 0,12648939 ! rRNA transcription GO:0009303 25 14 0,000 0,08566387 0,12762061 ! lactation GO:0007595 26 14 0,000 0,08566387 0,12754163 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,08566387 0,12746276 ! reproductive cellular process GO:0048610 20 14 0,000 0,08566387 0,12738398 ! tRNA modification GO:0006400 20 14 0,000 0,08566387 0,1273053 ! regulation of S phase GO:0033261 23 14 0,000 0,08566387 0,12722672 ! water transport GO:0006833 21 14 0,000 0,08566387 0,12714823 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08566387 0,12706984 ! non-recombinational repair GO:0000726 25 14 0,000 0,08566387 0,12699155 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08566387 0,12691335 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08566387 0,12683525 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08566387 0,12675724 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08566387 0,12667934 ! palate development GO:0060021 31 14 0,000 0,08566387 0,12660152 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08566387 0,12652381 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08566387 0,12644618 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08566387 0,12636866 ! arginine metabolic process GO:0006525 17 14 0,000 0,08566387 0,12629122 ! regulation of heart rate GO:0002027 24 14 0,000 0,08566387 0,12621389 ! organic alcohol transport GO:0015850 29 14 0,000 0,08566387 0,12613665 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08566387 0,1260595 ! embryo implantation GO:0007566 30 14 0,000 0,08566387 0,12598244 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08566387 0,12590548 ! L-amino acid transport GO:0015807 30 14 0,000 0,08566387 0,12582862 ! bone mineralization GO:0030282 17 14 0,000 0,08566387 0,12575185 ! stem cell development GO:0048864 43 14 0,000 0,08566387 0,12567517 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08566387 0,12559859 ! cerebellum development GO:0021549 21 14 0,000 0,08566387 0,12552209 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08566387 0,1254457 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08566387 0,12536939 ! cofactor transport GO:0051181 26 14 0,000 0,08566387 0,12529318 ! NADP metabolic process GO:0006739 24 14 0,000 0,08566387 0,12521706 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08566387 0,12514103 ! intestinal absorption GO:0050892 25 14 0,000 0,08566387 0,1250651 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08566387 0,12498925 ! oxygen transport GO:0015671 21 14 0,000 0,08566387 0,1249135 ! male genitalia development GO:0030539 24 14 0,000 0,08566387 0,12483784 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08566387 0,12476228 ! regulation of axon extension GO:0030516 37 14 0,000 0,08566387 0,1246868 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08566387 0,12461141 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,08868574 0,12892925 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,08868574 0,12885139 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,09062173 0,13158472 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0914956 0,13277347 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,0914956 0,13269344 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0914956 0,1326135 ! copper ion transport GO:0006825 20 15 0,000 0,0914956 0,13253367 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0914956 0,13245392 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0914956 0,13237427 ! sulfate transport GO:0008272 23 15 0,000 0,0914956 0,13229472 ! response to cAMP GO:0051591 22 15 0,000 0,0914956 0,13221527 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0914956 0,13213591 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0914956 0,13205664 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0914956 0,13197747 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0914956 0,13189839 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0914956 0,13181941 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0914956 0,13174053 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0914956 0,13166173 ! pituitary gland development GO:0021983 29 15 0,000 0,0914956 0,13158304 ! vesicle coating GO:0006901 33 15 0,000 0,0914956 0,13150443 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0914956 0,13142592 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0914956 0,1313475 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0914956 0,13126918 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0914956 0,13119095 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0914956 0,13111282 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0914956 0,13103477 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0914956 0,13095682 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0914956 0,13087896 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0914956 0,1308012 ! histone deacetylation GO:0016575 20 15 0,000 0,0914956 0,13072353 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0914956 0,13064595 ! tissue regeneration GO:0042246 26 15 0,000 0,0914956 0,13056846 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0914956 0,13049106 ! water homeostasis GO:0030104 27 15 0,000 0,0914956 0,13041375 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0914956 0,13033654 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0914956 0,13025942 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0914956 0,13018239 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0914956 0,13010545 ! cell killing GO:0001906 29 15 0,000 0,0914956 0,1300286 ! detection of bacterium GO:0016045 18 15 0,000 0,0914956 0,12995184 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0914956 0,12987517 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0914956 0,1297986 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0914956 0,12972211 ! peptide hormone processing GO:0016486 23 15 0,000 0,0914956 0,12964571 ! protein import into nucleus GO:0006606 158 80 1,000 0,09257013 0,13109107 ! T cell activation GO:0042110 168 81 1,000 0,09453071 0,13378875 ! digestion GO:0007586 112 81 1,000 0,09453071 0,1337101 ! nuclear import GO:0051170 161 81 1,000 0,09453071 0,13363154 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,09453071 0,13355307 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09729033 0,1373712 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09729033 0,13729063 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09729033 0,13721016 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09729033 0,13712978 ! bone remodeling GO:0046849 27 16 0,000 0,09729033 0,13704949 ! filopodium assembly GO:0046847 32 16 0,000 0,09729033 0,1369693 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,09729033 0,1368892 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09729033 0,13680919 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09729033 0,13672928 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09729033 0,13664946 ! startle response GO:0001964 28 16 0,000 0,09729033 0,13656974 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09729033 0,1364901 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09729033 0,13641056 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09729033 0,13633112 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09729033 0,13625176 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09729033 0,1361725 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09729033 0,13609333 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09729033 0,13601425 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09729033 0,13593527 ! response to osmotic stress GO:0006970 25 16 0,000 0,09729033 0,13585637 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09729033 0,13577757 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09729033 0,13569886 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09729033 0,13562024 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,09729033 0,13554171 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09729033 0,13546327 ! axon cargo transport GO:0008088 43 16 0,000 0,09729033 0,13538492 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09729033 0,13530666 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09729033 0,1352285 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,09729033 0,13515042 ! DNA replication initiation GO:0006270 27 16 0,000 0,09729033 0,13507243 ! neuron recognition GO:0008038 35 16 0,000 0,09729033 0,13499454 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09729033 0,13491673 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09729033 0,13483901 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09729033 0,13476139 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09729033 0,13468385 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09729033 0,1346064 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09729033 0,13452904 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09729033 0,13445177 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09729033 0,13437459 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09729033 0,13429749 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,09729033 0,13422049 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10304828 0,14208262 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,10304828 0,14200124 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10304828 0,14191996 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10304828 0,14183877 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10304828 0,14175767 ! signal complex assembly GO:0007172 41 17 0,000 0,10304828 0,14167667 ! endothelial cell migration GO:0043542 28 17 0,000 0,10304828 0,14159576 ! inositol metabolic process GO:0006020 28 17 0,000 0,10304828 0,14151494 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10304828 0,14143421 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10304828 0,14135358 ! glial cell development GO:0021782 27 17 0,000 0,10304828 0,14127303 ! limbic system development GO:0021761 36 17 0,000 0,10304828 0,14119258 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10304828 0,14111222 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10304828 0,14103195 ! heart looping GO:0001947 30 17 0,000 0,10304828 0,14095178 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10304828 0,14087169 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,10304828 0,14079169 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10304828 0,14071179 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10304828 0,14063198 ! glycine metabolic process GO:0006544 28 17 0,000 0,10304828 0,14055225 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,10304828 0,14047262 ! NAD metabolic process GO:0019674 29 17 0,000 0,10304828 0,14039308 ! membrane budding GO:0006900 37 17 0,000 0,10304828 0,14031362 ! DNA integration GO:0015074 29 17 0,000 0,10304828 0,14023426 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,10304828 0,14015499 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10304828 0,1400758 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10304828 0,13999671 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10304828 0,1399177 ! genitalia development GO:0048806 30 17 0,000 0,10304828 0,13983879 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10304828 0,13975996 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,10304828 0,13968122 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10304828 0,13960257 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10304828 0,13952401 ! steroid catabolic process GO:0006706 31 17 0,000 0,10304828 0,13944554 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10304828 0,13936716 ! gas transport GO:0015669 25 17 0,000 0,10304828 0,13928886 ! organic cation transport GO:0015695 31 17 0,000 0,10304828 0,13921065 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,10304828 0,13913253 ! amine biosynthetic process GO:0009309 138 86 1,000 0,1045083 0,14102467 ! protein localization in nucleus GO:0034504 176 87 1,000 0,10653718 0,14368188 ! cellular respiration GO:0045333 135 88 1,000 0,10857667 0,1463504 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,10857667 0,14626846 ! regulation of DNA binding GO:0051101 155 88 1,000 0,10857667 0,14618661 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,1087697 0,1463646 ! neuron maturation GO:0042551 42 18 0,000 0,1087697 0,14628279 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,1087697 0,14620107 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,1087697 0,14611944 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,1087697 0,1460379 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,1087697 0,14595645 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,1087697 0,14587509 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,1087697 0,14579382 ! memory GO:0007613 31 18 0,000 0,1087697 0,14571264 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,1087697 0,14563156 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,1087697 0,14555056 ! patterning of blood vessels GO:0001569 39 18 0,000 0,1087697 0,14546965 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,1087697 0,14538884 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,1087697 0,14530811 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,1087697 0,14522747 ! response to retinoic acid GO:0032526 26 18 0,000 0,1087697 0,14514693 ! response to fungus GO:0009620 21 18 0,000 0,1087697 0,14506647 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,1087697 0,1449861 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,1087697 0,14490582 ! vitamin transport GO:0051180 27 18 0,000 0,1087697 0,14482563 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,1087697 0,14474552 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,1087697 0,14466551 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,1087697 0,14458558 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,1087697 0,14450575 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,1087697 0,144426 ! nerve development GO:0021675 28 18 0,000 0,1087697 0,14434634 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,1087697 0,14426676 ! cellular defense response GO:0006968 114 89 1,000 0,11062655 0,14664874 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,11062655 0,14656799 ! sex differentiation GO:0007548 145 90 1,000 0,1126866 0,14921516 ! protein secretion GO:0009306 39 19 0,000 0,11445482 0,15147321 ! positive regulation of translation GO:0045727 30 19 0,000 0,11445482 0,15138993 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11445482 0,15130675 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,11445482 0,15122366 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,11445482 0,15114066 ! skin development GO:0043588 36 19 0,000 0,11445482 0,15105776 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,11445482 0,15097494 ! lipid phosphorylation GO:0046834 35 19 0,000 0,11445482 0,15089221 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11445482 0,15080958 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,11445482 0,15072703 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,11445482 0,15064458 ! bile acid metabolic process GO:0008206 29 19 0,000 0,11445482 0,15056221 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11445482 0,15047994 ! cerebral cortex development GO:0021987 36 19 0,000 0,11445482 0,15039776 ! pigmentation during development GO:0048066 41 19 0,000 0,11445482 0,15031566 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,11445482 0,15023366 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,11445482 0,15015174 ! heme metabolic process GO:0042168 36 19 0,000 0,11445482 0,15006991 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,11445482 0,14998818 ! plasma membrane fusion GO:0045026 28 19 0,000 0,11445482 0,14990653 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,11445482 0,14982497 ! peptide cross-linking GO:0018149 37 19 0,000 0,11445482 0,1497435 ! protein export from nucleus GO:0006611 36 19 0,000 0,11445482 0,14966211 ! heart process GO:0003015 30 19 0,000 0,11445482 0,14958082 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,11445482 0,14949961 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,11445482 0,1494185 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11445482 0,14933747 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,11445482 0,14925653 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,11445482 0,14917567 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,11445482 0,14909491 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,11445482 0,14901423 ! cilium assembly GO:0042384 37 19 0,000 0,11445482 0,14893363 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11445482 0,14885313 ! response to protein stimulus GO:0051789 149 91 1,000 0,11475661 0,149165 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,11475661 0,14908446 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,11892571 0,1544173 ! regulation of membrane potential GO:0042391 164 93 1,000 0,11892571 0,15433401 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,11892571 0,15425081 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,12010385 0,15569497 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,12010385 0,15561113 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,12010385 0,15552738 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,12010385 0,15544372 ! cAMP metabolic process GO:0046058 36 20 0,000 0,12010385 0,15536015 ! response to vitamin GO:0033273 31 20 0,000 0,12010385 0,15527666 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,12010385 0,15519327 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,12010385 0,15510997 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,12010385 0,15502675 ! retinoid metabolic process GO:0001523 32 20 0,000 0,12010385 0,15494363 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,12010385 0,1548606 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,12010385 0,15477765 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,12010385 0,15469479 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,12010385 0,15461202 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,12010385 0,15452934 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,12010385 0,15444675 ! body fluid secretion GO:0007589 31 20 0,000 0,12010385 0,15436425 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,12010385 0,15428183 ! peptide secretion GO:0002790 35 20 0,000 0,12010385 0,1541995 ! stem cell differentiation GO:0048863 53 20 0,000 0,12010385 0,15411726 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,12010385 0,15403511 ! sensory perception of pain GO:0019233 30 20 0,000 0,12010385 0,15395305 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,12010385 0,15387107 ! diencephalon development GO:0021536 34 20 0,000 0,12010385 0,15378918 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,12010385 0,15370738 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,12010385 0,15362566 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,12010385 0,15354403 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,12010385 0,15346249 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,12010385 0,15338104 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,12010385 0,15329967 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,12010385 0,15321838 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,12010385 0,15313719 ! regulation of glucose import GO:0046324 29 20 0,000 0,12010385 0,15305608 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,12010385 0,15297505 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,12010385 0,15289411 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,12010385 0,15281326 ! negative regulation of translation GO:0017148 29 20 0,000 0,12010385 0,15273249 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,12010385 0,15265181 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,12010385 0,15257121 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,12102437 0,15365944 ! female pregnancy GO:0007565 164 94 1,000 0,12102437 0,1535784 ! detection of stimulus GO:0051606 151 96 1,000 0,12524893 0,15885552 ! regulation of cell killing GO:0031341 42 21 0,000 0,12571704 0,15936522 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12571704 0,1592813 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12571704 0,15919747 ! hormone secretion GO:0046879 38 21 0,000 0,12571704 0,15911373 ! glycerol metabolic process GO:0006071 34 21 0,000 0,12571704 0,15903007 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12571704 0,1589465 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,12571704 0,15886302 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12571704 0,15877963 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12571704 0,15869633 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12571704 0,15861311 ! cytolysis GO:0019835 24 21 0,000 0,12571704 0,15852998 ! vasodilation GO:0042311 39 21 0,000 0,12571704 0,15844693 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12571704 0,15836398 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12571704 0,15828111 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12571704 0,15819832 ! DNA modification GO:0006304 34 21 0,000 0,12571704 0,15811563 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,12571704 0,15803302 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12571704 0,15795049 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,12571704 0,15786806 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,12571704 0,1577857 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,12571704 0,15770344 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12571704 0,15762126 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12571704 0,15753916 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12571704 0,15745716 ! collagen catabolic process GO:0030574 28 21 0,000 0,12571704 0,15737523 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12571704 0,15729339 ! protein ubiquitination GO:0016567 217 97 1,000 0,12737442 0,15928423 ! response to virus GO:0009615 160 98 1,000 0,12950847 0,16186876 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,1312946 0,164016 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,1312946 0,16393088 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,1312946 0,16384586 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,1312946 0,16376092 ! microtubule-based transport GO:0010970 54 22 0,000 0,1312946 0,16367607 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,1312946 0,16359131 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,1312946 0,16350663 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,1312946 0,16342204 ! keratinization GO:0031424 28 22 0,000 0,1312946 0,16333754 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,1312946 0,16325313 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,1312946 0,16316881 ! sensory perception of taste GO:0050909 28 22 0,000 0,1312946 0,16308457 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,1312946 0,16300042 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,1312946 0,16291635 ! vacuolar transport GO:0007034 36 22 0,000 0,1312946 0,16283238 ! lysosome organization GO:0007040 41 22 0,000 0,1312946 0,16274849 ! central nervous system neuron development GO:0021954 46 22 0,000 0,1312946 0,16266468 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,1312946 0,16258096 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,1312946 0,16249733 ! fucose metabolic process GO:0006004 39 22 0,000 0,1312946 0,16241379 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,1312946 0,16233032 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,1312946 0,16224695 GO:0060415|muscle tissue morphogenesis, ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,1312946 0,16216366 ! sarcomere organization GO:0045214 30 22 0,000 0,1312946 0,16208046 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,1312946 0,16199734 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,1312946 0,16191431 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,1312946 0,16183136 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,1312946 0,1617485 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,1312946 0,16166572 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,13683677 0,16840371 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,13683677 0,16831762 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,13683677 0,16823161 ! gluconeogenesis GO:0006094 33 23 0,000 0,13683677 0,16814569 ! viral genome replication GO:0019079 41 23 0,000 0,13683677 0,16805986 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13683677 0,16797411 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,13683677 0,16788845 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13683677 0,16780288 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13683677 0,1677174 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,13683677 0,16763201 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13683677 0,1675467 ! visual behavior GO:0007632 42 23 0,000 0,13683677 0,16746147 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,13683677 0,16737634 ! peroxisome organization GO:0007031 37 23 0,000 0,13683677 0,16729129 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13683677 0,16720633 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13683677 0,16712145 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13683677 0,16703666 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13683677 0,16695196 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,13683677 0,16686734 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,13683677 0,16678281 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,13683677 0,16669836 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,13683677 0,166614 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13683677 0,16652972 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13683677 0,16644553 ! platelet activation GO:0030168 37 23 0,000 0,13683677 0,16636142 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,13683677 0,1662774 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13683677 0,16619347 ! hormone transport GO:0009914 40 23 0,000 0,13683677 0,16610962 ! cell-cell recognition GO:0009988 25 23 0,000 0,13683677 0,16602585 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13683677 0,16594217 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,13683677 0,16585857 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,13683677 0,16577506 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,13683677 0,16569163 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,14234376 0,17227318 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,14234376 0,17218656 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,14234376 0,17210004 ! vesicle docking GO:0048278 47 24 0,000 0,14234376 0,1720136 ! spinal cord development GO:0021510 47 24 0,000 0,14234376 0,17192725 ! vacuole organization GO:0007033 43 24 0,000 0,14234376 0,17184098 ! digestive system process GO:0022600 39 24 0,000 0,14234376 0,1717548 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,14234376 0,17166871 ! regulation of behavior GO:0050795 43 24 0,000 0,14234376 0,1715827 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,14234376 0,17149678 ! membrane depolarization GO:0051899 39 24 0,000 0,14234376 0,17141095 ! pallium development GO:0021543 49 24 0,000 0,14234376 0,1713252 ! pentose metabolic process GO:0019321 35 24 0,000 0,14234376 0,17123954 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,14234376 0,17115396 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,14234376 0,17106847 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,14234376 0,17098306 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,14234376 0,17089774 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,14234376 0,17081251 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,14234376 0,17072736 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,14234376 0,17064229 ! regulation of amine transport GO:0051952 40 24 0,000 0,14234376 0,17055731 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,14781579 0,17702578 ! myelination GO:0042552 45 25 0,000 0,14781579 0,17693771 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14781579 0,17684972 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,14781579 0,17676183 ! phototransduction GO:0007602 33 25 0,000 0,14781579 0,17667402 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14781579 0,17658629 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,14781579 0,17649866 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,14781579 0,17641111 ! sperm motility GO:0030317 31 25 0,000 0,14781579 0,17632365 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14781579 0,17623627 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,14781579 0,17614898 ! chromosome condensation GO:0030261 45 25 0,000 0,14781579 0,17606178 ! neural crest cell development GO:0014032 54 25 0,000 0,14781579 0,17597466 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,14781579 0,17588763 ! negative regulation of cell development GO:0010721 73 25 0,000 0,14781579 0,17580069 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14781579 0,17571383 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14781579 0,17562706 ! interaction with host GO:0051701 62 25 0,000 0,14781579 0,17554037 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14781579 0,17545377 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,14781579 0,17536726 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14781579 0,17528083 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,14781579 0,17519448 ! immunoglobulin production GO:0002377 55 25 0,000 0,14781579 0,17510822 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14781579 0,17502205 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14781579 0,17493595 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,14781579 0,17484995 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14781579 0,17476403 ! telomere organization GO:0032200 43 25 0,000 0,14781579 0,17467819 GO:0000723|telomere maintenance, ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,1532531 0,1810147 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,1532531 0,18092588 ! initiation of viral infection GO:0019059 57 26 0,000 0,1532531 0,18083715 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,1532531 0,18074851 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,1532531 0,18065995 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,1532531 0,18057147 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,1532531 0,18048309 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,1532531 0,18039479 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,1532531 0,18030658 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,1532531 0,18021845 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,1532531 0,18013041 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,1532531 0,18004246 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,1532531 0,17995459 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,1532531 0,17986681 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,1532531 0,17977911 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,1532531 0,1796915 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,1532531 0,17960397 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,1532531 0,17951653 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,1532531 0,17942917 ! neuron fate commitment GO:0048663 48 27 0,000 0,15865589 0,18566443 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,15865589 0,18557417 ! iron ion transport GO:0006826 59 27 0,000 0,15865589 0,185484 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15865589 0,18539391 ! protein amino acid acylation GO:0043543 55 27 0,000 0,15865589 0,18530392 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15865589 0,18521401 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,15865589 0,18512418 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15865589 0,18503445 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,15865589 0,1849448 ! autophagy GO:0006914 41 27 0,000 0,15865589 0,18485524 ! base-excision repair GO:0006284 41 27 0,000 0,15865589 0,18476576 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15865589 0,18467638 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,15865589 0,18458707 ! glutathione metabolic process GO:0006749 39 27 0,000 0,15865589 0,18449786 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15865589 0,18440873 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,15865589 0,18431969 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,15865589 0,18423073 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,16402439 0,19037273 ! circadian rhythm GO:0007623 50 28 0,000 0,16402439 0,19028094 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,16402439 0,19018924 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,16402439 0,19009763 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,16402439 0,1900061 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16402439 0,18991466 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16402439 0,18982331 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16402439 0,18973205 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,16402439 0,18964088 ! synaptogenesis GO:0007416 42 28 0,000 0,16402439 0,18954979 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,16402439 0,1894588 ! lipid oxidation GO:0034440 43 28 0,000 0,16402439 0,18936788 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16402439 0,18927706 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,16402439 0,18918632 ! translational initiation GO:0006413 65 29 0,000 0,1693588 0,19524546 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,1693588 0,19515195 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,1693588 0,19505854 ! regulation of pH GO:0006885 43 29 0,000 0,1693588 0,19496521 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,1693588 0,19487197 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,1693588 0,19477882 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,1693588 0,19468575 ! detection of light stimulus GO:0009583 38 29 0,000 0,1693588 0,19459278 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,1693588 0,1944999 ! regulation of coagulation GO:0050818 46 29 0,000 0,1693588 0,1944071 ! zinc ion transport GO:0006829 45 30 0,000 0,17465936 0,200396 ! membrane docking GO:0022406 61 30 0,000 0,17465936 0,20030049 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,17465936 0,20020506 ! regulation of innate immune response GO:0045088 51 30 0,000 0,17465936 0,20010972 ! acute-phase response GO:0006953 49 30 0,000 0,17465936 0,20001448 ! myofibril assembly GO:0030239 47 30 0,000 0,17465936 0,19991932 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,17465936 0,19982426 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,17465936 0,19972929 ! phospholipid transport GO:0015914 51 30 0,000 0,17465936 0,1996344 ! ensheathment of neurons GO:0007272 57 30 0,000 0,17465936 0,19953961 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,17465936 0,19944491 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,17465936 0,19935029 ! eye morphogenesis GO:0048592 60 30 0,000 0,17465936 0,19925577 ! regulation of B cell activation GO:0050864 50 30 0,000 0,17465936 0,19916134 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,17992627 0,20506992 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,17992627 0,20497282 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17992627 0,20487581 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17992627 0,2047789 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,17992627 0,20468208 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,17992627 0,20458535 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,17992627 0,20448871 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,17992627 0,20439216 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,17992627 0,2042957 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,17992627 0,20419934 ! peptide transport GO:0015833 55 31 0,000 0,17992627 0,20410306 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17992627 0,20400688 ! natural killer cell activation GO:0030101 45 31 0,000 0,17992627 0,20391078 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,17992627 0,20381478 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,17992627 0,20371887 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,17992627 0,20362305 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,18515973 0,20944726 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,18515973 0,20934884 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,18515973 0,2092505 ! cholesterol transport GO:0030301 56 32 0,000 0,18515973 0,20915226 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,18515973 0,20905412 ! spliceosome assembly GO:0000245 67 32 0,000 0,18515973 0,20895606 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,18515973 0,2088581 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,18515973 0,20876023 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,18515973 0,20866245 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,18515973 0,20856476 ! muscle cell development GO:0055001 49 32 0,000 0,18515973 0,20846716 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,18515973 0,20836965 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,18515973 0,20827224 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,18515973 0,20817492 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,18515973 0,20807768 ! peripheral nervous system development GO:0007422 64 32 0,000 0,18515973 0,20798054 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,18515973 0,20788349 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,18515973 0,20778653 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,19035998 0,21352266 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,19035998 0,21342316 ! protein targeting to membrane GO:0006612 68 33 0,000 0,19035998 0,21332376 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,19035998 0,21322444 ! cell fate specification GO:0001708 52 33 0,000 0,19035998 0,21312522 ! sterol transport GO:0015918 57 33 0,000 0,19035998 0,2130261 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,19035998 0,21292706 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,19035998 0,21282812 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,19035998 0,21272927 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,19552721 0,21840226 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,19552721 0,21830091 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,19552721 0,21819966 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,19552721 0,2180985 ! mismatch repair GO:0006298 46 34 0,000 0,19552721 0,21799743 ! spermatid development GO:0007286 63 34 0,000 0,19552721 0,21789646 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,19552721 0,21779558 ! negative regulation of secretion GO:0051048 63 35 0,000 0,20066163 0,22341133 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,20066163 0,22330799 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,20066163 0,22320475 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,20066163 0,22310161 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,20066163 0,22299856 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,20066163 0,2228956 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,20066163 0,22279274 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,20066163 0,22268998 ! cytokine production GO:0001816 59 35 0,000 0,20066163 0,22258731 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,20066163 0,22248473 ! vesicle localization GO:0051648 64 35 0,000 0,20066163 0,22238225 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,20576345 0,22793133 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,20576345 0,22782644 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,20576345 0,22772164 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,20576345 0,22761694 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,20576345 0,22751234 ! regulation of proteolysis GO:0030162 72 36 0,000 0,20576345 0,22740783 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,20576345 0,22730342 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,20576345 0,22719911 ! aerobic respiration GO:0009060 55 36 0,000 0,20576345 0,22709489 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,20576345 0,22699076 ! RNA export from nucleus GO:0006405 56 37 0,000 0,21083287 0,23247658 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,21083287 0,23237008 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,21083287 0,23226369 ! actomyosin structure organization GO:0031032 62 37 0,000 0,21083287 0,23215739 ! organic anion transport GO:0015711 68 37 0,000 0,21083287 0,23205119 ! tissue remodeling GO:0048771 76 37 0,000 0,21083287 0,23194508 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,21083287 0,23183907 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,21083287 0,23173316 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,21083287 0,23162735 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,21083287 0,23152163 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,21083287 0,23141601 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,21083287 0,23131049 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,21587011 0,23672903 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,21587011 0,23662118 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,21587011 0,23651343 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,21587011 0,23640577 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,21587011 0,23629822 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,21587011 0,23619076 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,21587011 0,2360834 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,21587011 0,23597614 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mRNA catabolic process GO:0006402 71 39 0,000 0,22087536 0,24133793 ! mammary gland development GO:0030879 86 39 0,000 0,22087536 0,24122838 ! learning GO:0007612 77 39 0,000 0,22087536 0,24111893 ! organic ether metabolic process GO:0018904 55 39 0,000 0,22087536 0,24100958 ! segmentation GO:0035282 67 39 0,000 0,22087536 0,24090033 ! ion transmembrane transport GO:0034220 66 39 0,000 0,22087536 0,24079117 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,22087536 0,24068212 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,22087536 0,24057316 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,22584883 0,24587886 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,22584883 0,24576765 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,22584883 0,24565655 ! feeding behavior GO:0007631 59 40 0,000 0,22584883 0,24554554 ! negative regulation of binding GO:0051100 72 40 0,000 0,22584883 0,24543463 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,22584883 0,24532383 ! maintenance of protein location GO:0045185 91 40 0,000 0,22584883 0,24521312 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,23079071 0,2504657 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,23079071 0,25035277 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,23079071 0,25023995 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,23079071 0,25012723 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,23079071 0,25001461 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,23079071 0,24990209 ! polyol metabolic process GO:0019751 66 41 0,000 0,23079071 0,24978968 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,23079071 0,24967736 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,23570121 0,25487511 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,23570121 0,25476061 ! regulation of tube size GO:0035150 71 42 0,000 0,23570121 0,25464621 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,23570121 0,25453192 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,23570121 0,25441773 ! neuron migration GO:0001764 79 42 0,000 0,23570121 0,25430364 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,24058053 0,2594517 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,24058053 0,25933546 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,24058053 0,25921932 ! striated muscle contraction GO:0006941 77 43 0,000 0,24058053 0,25910329 ! phagocytosis GO:0006909 90 43 0,000 0,24058053 0,25898736 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,24542885 0,26408847 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,24542885 0,26397041 ! double-strand break repair GO:0006302 81 44 0,000 0,24542885 0,26385246 ! biopolymer methylation GO:0043414 84 44 0,000 0,24542885 0,26373462 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,24542885 0,26361688 ! maintenance of location in cell GO:0051651 97 44 0,000 0,24542885 0,26349925 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,25024638 0,26855165 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,25024638 0,26843192 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,25024638 0,2683123 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,25024638 0,26819278 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,25024638 0,26807337 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,25024638 0,26795407 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,25503332 0,27295826 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,25503332 0,27283689 ! positive regulation of defense response GO:0031349 76 47 0,000 0,25978985 0,27780194 ! response to calcium ion GO:0051592 81 47 0,000 0,25978985 0,27767853 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,25978985 0,27755523 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,25978985 0,27743203 ! JNK cascade GO:0007254 91 47 0,000 0,25978985 0,27730895 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,25978985 0,27718597 ! methylation GO:0032259 90 47 0,000 0,25978985 0,27706311 ! Notch signaling pathway GO:0007219 96 48 0,000 0,26451616 0,28197868 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,26451616 0,2818538 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,26451616 0,28172904 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,26451616 0,28160438 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,26451616 0,28147983 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,26921246 0,28635065 ! regulation of action potential GO:0001508 95 49 0,000 0,26921246 0,28622412 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,26921246 0,28609769 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,26921246 0,28597138 ! regulation of ion transport GO:0043269 77 49 0,000 0,26921246 0,28584518 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,26921246 0,28571909 ! peptide metabolic process GO:0006518 76 49 0,000 0,26921246 0,28559311 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,26921246 0,28546724 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,26921246 0,28534149 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,26921246 0,28521584 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,27387892 0,29003199 ! neuromuscular process GO:0050905 99 50 0,000 0,27387892 0,28990439 ! inner ear development GO:0048839 79 50 0,000 0,27387892 0,28977691 ! histone modification GO:0016570 91 50 0,000 0,27387892 0,28964953 ! viral infectious cycle GO:0019058 99 51 0,000 0,27851574 0,29442393 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,27851574 0,29429463 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,27851574 0,29416544 ! excretion GO:0007588 83 51 0,000 0,27851574 0,29403636 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,27851574 0,2939074 ! chromatin remodeling GO:0006338 109 51 0,000 0,27851574 0,29377855 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,27851574 0,29364981 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,27851574 0,29352119 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,27851574 0,29339268 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,2831231 0,29811562 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,2831231 0,29798521 ! membrane fusion GO:0006944 110 52 0,000 0,2831231 0,29785491 ! amino acid activation GO:0043038 92 52 0,000 0,2831231 0,29772473 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,2831231 0,29759467 ! RNA catabolic process GO:0006401 93 53 0,000 0,2877012 0,30227471 ! regulation of translational initiation GO:0006446 82 53 0,000 0,2877012 0,30214277 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,2877012 0,30201094 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,2877012 0,30187923 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,2877012 0,30174764 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,2877012 0,30161616 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,29225021 0,30625174 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,29225021 0,30611841 ! cell recognition GO:0008037 85 54 0,000 0,29225021 0,3059852 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,29225021 0,30585211 ! chloride transport GO:0006821 90 55 0,000 0,29677031 0,31044755 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,29677031 0,31031263 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,29677031 0,31017783 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,29677031 0,31004315 ! RNA elongation GO:0006354 79 55 0,000 0,29677031 0,30990858 ! nuclear export GO:0051168 97 55 0,000 0,29677031 0,30977413 ! regulation of actin filament length GO:0030832 105 56 0,000 0,3012617 0,31432595 ! sensory perception of smell GO:0007608 80 56 0,000 0,3012617 0,31418971 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,3012617 0,31405357 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,3012617 0,31391756 ! proton transport GO:0015992 94 56 0,000 0,3012617 0,31378167 ! lipid modification GO:0030258 97 57 0,000 0,30572455 0,3182922 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,30572455 0,31815453 ! maintenance of location GO:0051235 118 57 0,000 0,30572455 0,31801698 ! hydrogen transport GO:0006818 97 58 0,000 0,31015904 0,32249035 ! regulation of endocytosis GO:0030100 91 58 0,000 0,31015904 0,32235104 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,31015904 0,32221186 ! positive regulation of secretion GO:0051047 95 59 0,000 0,31456536 0,32664836 ! regulation of cellular component size GO:0032535 109 59 0,000 0,31456536 0,32650745 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,31456536 0,32636665 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,31456536 0,32622597 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,31456536 0,32608542 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,31894368 0,33048169 ! camera-type eye development GO:0043010 116 60 0,000 0,31894368 0,33033943 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,31894368 0,33019728 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,32329417 0,33455732 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,32329417 0,33441349 ! tRNA processing GO:0008033 89 61 0,000 0,32329417 0,33426978 ! viral reproductive process GO:0022415 126 62 0,000 0,32761702 0,33859388 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,32761702 0,3384485 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,3319124 0,34273872 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,3319124 0,34259169 ! cell redox homeostasis GO:0045454 102 64 0,000 0,33618047 0,34684829 ! single fertilization GO:0007338 75 64 0,000 0,33618047 0,34669962 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,34042143 0,35092286 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,34463543 0,3551147 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,34463543 0,35496269 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,34882264 0,35912164 ! lung development GO:0030324 144 67 0,000 0,34882264 0,35896804 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,34882264 0,35881457 ! amino acid transport GO:0006865 125 68 0,000 0,35298324 0,36293918 ! viral reproduction GO:0016032 134 68 0,000 0,35298324 0,36278414 ! regulation of lipase activity GO:0060191 130 68 0,000 0,35298324 0,36262924 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,3571174 0,36671978 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,3571174 0,36656333 ! amine catabolic process GO:0009310 117 71 0,000 0,36530704 0,37480969 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,36936285 0,37880947 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,36936285 0,37864807 ! respiratory system development GO:0060541 153 72 0,000 0,36936285 0,37848681 ! learning or memory GO:0007611 147 73 0,000 0,37339288 0,3824535 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,37339288 0,38229076 ! axon guidance GO:0007411 139 73 0,000 0,37339288 0,38212815 ! fertilization GO:0009566 90 73 0,000 0,37339288 0,38196568 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,3773973 0,38589796 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,3773973 0,38573403 ! exocytosis GO:0006887 133 74 0,000 0,3773973 0,38557023 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,3773973 0,38540658 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,38137625 0,38930473 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,38137625 0,38913964 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,38137625 0,38897468 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,38532991 0,39284058 ! defense response to bacterium GO:0042742 89 76 0,000 0,38532991 0,39267419 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,38532991 0,39250794 ! regulation of catabolic process GO:0009894 161 76 0,000 0,38532991 0,39234184 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,38925843 0,39617419 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,38925843 0,39600667 ! blood coagulation GO:0007596 146 78 0,000 0,39316197 0,39980883 GO:0050817|coagulation, ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,39704069 0,40358255 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,39704069 0,40341212 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,39704069 0,40324183 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,40089475 0,40698429 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,40089475 0,40681264 ! inorganic anion transport GO:0015698 138 80 0,000 0,40089475 0,40664113 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,4047243 0,41035258 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,4047243 0,41017972 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,4085295 0,41386188 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,4085295 0,4136877 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,4085295 0,41351366 ! regulation of lyase activity GO:0051339 160 83 0,000 0,4123105 0,41716529 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,41606745 0,42078953 ! hemostasis GO:0007599 158 84 0,000 0,41606745 0,42061273 ! negative regulation of transport GO:0051051 153 84 0,000 0,41606745 0,42043607 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,41606745 0,42025957 ! response to unfolded protein GO:0006986 131 85 0,000 0,41980051 0,4238523 ! nucleosome assembly GO:0006334 122 85 0,000 0,41980051 0,42367451 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,41980051 0,42349687 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,42350983 0,42705979 ! chromatin assembly GO:0031497 124 86 0,000 0,42350983 0,42688088 ! amine transport GO:0015837 155 86 0,000 0,42350983 0,42670212 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,42719556 0,43023546 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,42719556 0,43005545 ! regulation of neurological system process GO:0031644 148 88 0,000 0,43085785 0,43356085 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,43085785 0,43337959 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,43811269 0,44049274 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,43811269 0,44030874 ! sterol metabolic process GO:0016125 152 91 0,000 0,44170553 0,44373424 ! regulation of defense response GO:0031347 149 92 0,000 0,44527552 0,44713393 ! nucleosome organization GO:0034728 138 92 0,000 0,44527552 0,44694739 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,44527552 0,44676101 ! vitamin metabolic process GO:0006766 139 92 0,000 0,44527552 0,44657478 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,4488228 0,44994486 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,4488228 0,44975746 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,45584981 0,45660892 ! mRNA transport GO:0051028 169 96 0,000 0,45932982 0,45990326 ! hormone metabolic process GO:0042445 157 97 0,000 0,46278769 0,4631727 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,46622355 0,46641741 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,46963756 0,46963756