pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1292-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of glycolysis GO:0045821 11 5 2,000 5,112E-07 1,176E-03 ! nuclear migration GO:0007097 10 5 2,000 5,112E-07 5,879E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 5,112E-07 3,919E-04 GO:0031272|regulation of pseudopodium assembly, ! macrophage differentiation GO:0030225 10 6 2,000 1,02E-06 5,863E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 2,000 1,02E-06 4,69E-04 ! positive regulation of cell migration GO:0030335 92 51 4,000 1,35E-06 5,176E-04 ! peptidyl-amino acid modification GO:0018193 147 93 5,000 1,353E-06 4,446E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 3,000 1,554E-06 4,468E-04 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 1,78E-06 4,548E-04 ! establishment of nucleus localization GO:0040023 13 7 2,000 1,78E-06 4,093E-04 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 1,86E-06 3,889E-04 ! regulation of oxidoreductase activity GO:0051341 39 24 3,000 1,86E-06 3,565E-04 ! positive regulation of cell motion GO:0051272 99 56 4,000 2,164E-06 3,829E-04 ! peptidyl-tyrosine modification GO:0018212 37 25 3,000 2,208E-06 3,627E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 2,84E-06 4,354E-04 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 2,000 2,84E-06 4,082E-04 ! positive regulation of glucose metabolic process GO:0010907 15 9 2,000 4,248E-06 5,747E-04 ! regulation of glycolysis GO:0006110 15 9 2,000 4,248E-06 5,428E-04 ! nucleus localization GO:0051647 15 9 2,000 4,248E-06 5,142E-04 ! regulation of cell projection assembly GO:0060491 20 10 2,000 6,052E-06 6,96E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 2,000 6,052E-06 6,628E-04 GO:0043470|regulation of carbohydrate catabolic process, ! cellular response to insulin stimulus GO:0032869 52 34 3,000 7,89E-06 8,248E-04 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 2,000 8,299E-06 8,299E-04 ! filopodium assembly GO:0046847 19 11 2,000 8,299E-06 7,953E-04 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 2,000 8,299E-06 7,635E-04 ! cellular response to hormone stimulus GO:0032870 109 74 4,000 8,661E-06 7,661E-04 ! response to nutrient GO:0007584 104 75 4,000 9,252E-06 7,882E-04 ! positive regulation of cellular catabolic process GO:0031331 22 12 2,000 1,104E-05 9,065E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 2,000 1,104E-05 8,752E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! microspike assembly GO:0030035 23 12 2,000 1,104E-05 8,46E-04 ! regulation of monooxygenase activity GO:0032768 26 13 2,000 1,431E-05 1,062E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 1,808E-05 1,3E-03 ! interphase GO:0051325 159 88 4,000 2,022E-05 1,409E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 2,047E-05 1,385E-03 ! response to insulin stimulus GO:0032868 63 43 3,000 2,047E-05 1,345E-03 ! positive regulation of oxidoreductase activity GO:0051353 21 15 2,000 2,264E-05 1,446E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 2,457E-05 1,527E-03 ! regulation of glucose metabolic process GO:0010906 22 16 2,000 2,779E-05 1,682E-03 ! branched chain family amino acid metabolic process GO:0009081 24 16 2,000 2,779E-05 1,639E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 2,000 2,779E-05 1,598E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 3,365E-05 1,888E-03 ! regulation of angiogenesis GO:0045765 94 49 3,000 3,455E-05 1,892E-03 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 2,000 4,027E-05 2,154E-03 ! response to retinoic acid GO:0032526 25 18 2,000 4,027E-05 2,105E-03 ! establishment of organelle localization GO:0051656 85 52 3,000 4,377E-05 2,237E-03 ! regulation of carbohydrate metabolic process GO:0006109 28 19 2,000 4,769E-05 2,385E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to vitamin A GO:0033189 26 19 2,000 4,769E-05 2,334E-03 ! regulation of protein complex assembly GO:0043254 81 54 3,000 5,084E-05 2,436E-03 ! response to vitamin GO:0033273 29 20 2,000 5,596E-05 2,627E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 5,596E-05 2,574E-03 ! response to peptide hormone stimulus GO:0043434 84 57 3,000 6,296E-05 2,839E-03 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 6,511E-05 2,88E-03 ! vasculogenesis GO:0001570 33 22 2,000 7,519E-05 3,263E-03 ! cell-matrix adhesion GO:0007160 114 61 3,000 8,224E-05 3,503E-03 ! acetyl-CoA metabolic process GO:0006084 33 23 2,000 8,623E-05 3,606E-03 ! organelle localization GO:0051640 96 62 3,000 8,767E-05 3,601E-03 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 9,829E-05 3,966E-03 ! regulation of cellular catabolic process GO:0031329 36 24 2,000 9,829E-05 3,898E-03 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 9,829E-05 3,832E-03 ! cell-substrate adhesion GO:0031589 121 66 3,000 1,12E-04 4,293E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 1,256E-04 4,735E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,394E-04 5,17E-03 ! regulation of hormone biosynthetic process GO:0046885 7 5 1,000 1,394E-04 5,087E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,394E-04 5,008E-03 ! embryonic hemopoiesis GO:0035162 10 5 1,000 1,394E-04 4,931E-03 ! valine metabolic process GO:0006573 8 5 1,000 1,394E-04 4,856E-03 ! peptidyl-histidine phosphorylation GO:0018106 7 5 1,000 1,394E-04 4,784E-03 ! positive regulation of chemokine production GO:0032722 7 5 1,000 1,394E-04 4,713E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,394E-04 4,645E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,394E-04 4,579E-03 ! response to hypoxia GO:0001666 132 72 3,000 1,572E-04 5,091E-03 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 1,574E-04 5,027E-03 ! cell junction assembly GO:0034329 56 28 2,000 1,574E-04 4,958E-03 ! positive regulation of catabolic process GO:0009896 40 28 2,000 1,574E-04 4,891E-03 ! response to oxygen levels GO:0070482 137 74 3,000 1,748E-04 5,36E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 2,085E-04 6,31E-03 ! mRNA stabilization GO:0048255 15 6 1,000 2,085E-04 6,229E-03 GO:0043489|RNA stabilization, ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 2,085E-04 6,149E-03 ! male sex determination GO:0030238 9 6 1,000 2,085E-04 6,071E-03 ! gas homeostasis GO:0033483 11 6 1,000 2,085E-04 5,995E-03 ! peptidyl-histidine modification GO:0018202 9 6 1,000 2,085E-04 5,921E-03 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 2,000 2,586E-04 7,253E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 63 33 2,000 2,586E-04 7,166E-03 ! carbohydrate homeostasis GO:0033500 39 33 2,000 2,586E-04 7,08E-03 GO:0042593|glucose homeostasis, ! cytokinesis GO:0000910 52 33 2,000 2,586E-04 6,997E-03 ! ossification GO:0001503 134 82 3,000 2,598E-04 6,947E-03 GO:0060348|bone development, ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 2,829E-04 7,478E-03 ! neuron migration GO:0001764 46 34 2,000 2,829E-04 7,393E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,912E-04 7,526E-03 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 2,912E-04 7,442E-03 ! T-helper 1 type immune response GO:0042088 11 7 1,000 2,912E-04 7,36E-03 ! hemoglobin metabolic process GO:0020027 10 7 1,000 2,912E-04 7,28E-03 ! protein heterooligomerization GO:0051291 10 7 1,000 2,912E-04 7,202E-03 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 2,912E-04 7,125E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 2,982E-04 7,219E-03 ! tissue remodeling GO:0048771 62 36 2,000 3,357E-04 8,042E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 3,873E-04 9,184E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 3,873E-04 9,091E-03 ! induction of positive chemotaxis GO:0050930 14 8 1,000 3,873E-04 8,999E-03 ! succinate metabolic process GO:0006105 14 8 1,000 3,873E-04 8,909E-03 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 3,873E-04 8,821E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,873E-04 8,734E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 3,873E-04 8,649E-03 ! S phase GO:0051320 8 8 1,000 3,873E-04 8,566E-03 GO:0000084|S phase of mitotic cell cycle, ! branched chain family amino acid catabolic process GO:0009083 11 8 1,000 3,873E-04 8,485E-03 ! regulation of embryonic development GO:0045995 16 8 1,000 3,873E-04 8,405E-03 ! multicellular organismal metabolic process GO:0044236 50 39 2,000 4,262E-04 9,161E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 4,595E-04 9,786E-03 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 4,742E-04 0,01000674 ! regulation of developmental growth GO:0048638 13 9 1,000 4,968E-04 0,01038757 ! lung alveolus development GO:0048286 17 9 1,000 4,968E-04 0,01029399 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 4,968E-04 0,01020208 ! phosphagen metabolic process GO:0006599 12 9 1,000 4,968E-04 0,01011179 GO:0006600|creatine metabolic process, ! regulation of hormone metabolic process GO:0032350 15 9 1,000 4,968E-04 0,01002309 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 4,968E-04 9,936E-03 ! embryonic placenta development GO:0001892 12 9 1,000 4,968E-04 9,85E-03 ! localization within membrane GO:0051668 15 9 1,000 4,968E-04 9,766E-03 ! regulation of cell shape GO:0008360 78 42 2,000 5,311E-04 0,01035136 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 5,694E-04 0,01100453 ! regulation of cell projection organization GO:0031344 83 44 2,000 6,094E-04 0,01167984 ! glycolysis GO:0006096 53 44 2,000 6,094E-04 0,01158332 ! negative regulation of muscle development GO:0048635 12 10 1,000 6,195E-04 0,01167878 ! regulation of B cell proliferation GO:0030888 15 10 1,000 6,195E-04 0,01158383 ! blood vessel remodeling GO:0001974 21 10 1,000 6,195E-04 0,01149041 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 6,195E-04 0,01139849 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 6,195E-04 0,01130802 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 6,195E-04 0,01121898 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 1,000 6,195E-04 0,01113133 ! regulation of bone resorption GO:0045124 24 10 1,000 6,195E-04 0,01104505 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 6,195E-04 0,01096008 ! positive regulation of cell cycle GO:0045787 77 45 2,000 6,512E-04 0,0114325 ! response to UV GO:0009411 75 46 2,000 6,947E-04 0,01210484 ! virus-host interaction GO:0019048 17 11 1,000 7,553E-04 0,01306161 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 7,553E-04 0,01296413 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 24 11 1,000 7,553E-04 0,0128681 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 1,000 7,553E-04 0,01277348 ! regulation of leukocyte migration GO:0002685 24 11 1,000 7,553E-04 0,01268025 ! heart morphogenesis GO:0003007 65 48 2,000 7,873E-04 0,01312172 ! cartilage development GO:0051216 70 49 2,000 8,364E-04 0,01383965 ! positive regulation of growth GO:0045927 67 50 2,000 8,874E-04 0,01457861 ! cartilage condensation GO:0001502 18 12 1,000 9,042E-04 0,01474863 ! heart looping GO:0001947 15 12 1,000 9,042E-04 0,01464476 ! cell-cell junction assembly GO:0007043 18 12 1,000 9,042E-04 0,01454235 ! histone acetylation GO:0016573 23 12 1,000 9,042E-04 0,01444136 ! peptidyl-lysine modification GO:0018205 18 12 1,000 9,042E-04 0,01434177 ! regulation of mRNA stability GO:0043488 27 12 1,000 9,042E-04 0,01424354 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 9,042E-04 0,01414664 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 9,403E-04 0,01461313 ! cell projection assembly GO:0030031 76 53 2,000 1,052E-03 0,01624039 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,066E-03 0,0163445 ! regulation of chemokine production GO:0032642 17 13 1,000 1,066E-03 0,01623625 ! regulation of RNA stability GO:0043487 28 13 1,000 1,066E-03 0,01612944 ! glucose catabolic process GO:0006007 66 54 2,000 1,111E-03 0,01670119 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 1,235E-03 0,01844401 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 1,235E-03 0,01832502 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,241E-03 0,01829055 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,241E-03 0,01817405 ! response to cAMP GO:0051591 19 14 1,000 1,241E-03 0,01805902 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 1,241E-03 0,01794544 ! muscle maintenance GO:0046716 19 14 1,000 1,241E-03 0,01783328 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 1,241E-03 0,01772252 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,3E-03 0,0184576 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,367E-03 0,01929306 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,428E-03 0,02002615 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 1,428E-03 0,01990478 ! lipid phosphorylation GO:0046834 23 15 1,000 1,428E-03 0,01978487 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,428E-03 0,0196664 ! activation of MAPK activity GO:0000187 84 59 2,000 1,437E-03 0,01966875 ! lung development GO:0030324 94 59 2,000 1,437E-03 0,01955237 ! myeloid cell differentiation GO:0030099 85 59 2,000 1,437E-03 0,01943736 ! regulation of homeostatic process GO:0032844 105 60 2,000 1,508E-03 0,02028617 ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,582E-03 0,02115452 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,628E-03 0,02164359 ! neural crest cell migration GO:0001755 24 16 1,000 1,628E-03 0,02151921 ! respiratory tube development GO:0030323 99 62 2,000 1,658E-03 0,0217905 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 1,736E-03 0,02268903 ! hexose catabolic process GO:0019320 82 64 2,000 1,817E-03 0,02360694 ! respiratory system development GO:0060541 100 64 2,000 1,817E-03 0,02347432 ! forelimb morphogenesis GO:0035136 19 17 1,000 1,841E-03 0,02364954 ! cell-substrate junction assembly GO:0007044 39 17 1,000 1,841E-03 0,02351815 ! actin filament bundle formation GO:0051017 26 17 1,000 1,841E-03 0,02338822 ! cell-cell junction organization GO:0045216 25 17 1,000 1,841E-03 0,02325971 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,841E-03 0,02313261 ! positive regulation of DNA replication GO:0045740 29 18 1,000 2,066E-03 0,02581982 ! positive regulation of anti-apoptosis GO:0045768 29 18 1,000 2,066E-03 0,02568026 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 2,066E-03 0,02554219 ! somitogenesis GO:0001756 24 18 1,000 2,066E-03 0,0254056 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 2,066E-03 0,02527047 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 2,303E-03 0,02802574 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 2,303E-03 0,02787824 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 2,303E-03 0,02773228 ! sex determination GO:0007530 29 19 1,000 2,303E-03 0,02758784 ! plasma membrane fusion GO:0045026 23 19 1,000 2,303E-03 0,0274449 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 2,303E-03 0,02730343 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 2,303E-03 0,02716341 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 2,303E-03 0,02702482 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 2,349E-03 0,02742203 ! regulation of catabolic process GO:0009894 106 70 2,000 2,349E-03 0,02728354 ! monosaccharide catabolic process GO:0046365 91 71 2,000 2,446E-03 0,02826817 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 2,545E-03 0,02927115 GO:0045937|positive regulation of phosphate metabolic process, ! hindlimb morphogenesis GO:0035137 32 20 1,000 2,553E-03 0,02920948 ! positive regulation of locomotion GO:0040017 35 20 1,000 2,553E-03 0,02906487 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 31 20 1,000 2,553E-03 0,0289217 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 2,815E-03 0,03173212 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 2,815E-03 0,03157733 ! protein amino acid acylation GO:0043543 37 21 1,000 2,815E-03 0,03142404 ! regulation of chemotaxis GO:0050920 36 21 1,000 2,815E-03 0,03127223 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 2,815E-03 0,03112188 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 2,815E-03 0,03097298 ! acetyl-CoA catabolic process GO:0046356 31 21 1,000 2,815E-03 0,03082549 GO:0006099|tricarboxylic acid cycle, ! negative regulation of growth GO:0045926 123 75 2,000 2,859E-03 0,03116177 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 2,968E-03 0,03220295 ! regulation of adenylate cyclase activity GO:0045761 131 77 2,000 3,08E-03 0,03326193 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 3,088E-03 0,03319343 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 3,088E-03 0,03303904 ! regulation of anti-apoptosis GO:0045767 36 22 1,000 3,088E-03 0,03288608 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 3,088E-03 0,03273453 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 3,088E-03 0,03258438 GO:0010810|regulation of cell-substrate adhesion, ! coenzyme catabolic process GO:0009109 33 22 1,000 3,088E-03 0,03243559 ! regulation of behavior GO:0050795 38 22 1,000 3,088E-03 0,03228815 ! neural tube closure GO:0001843 33 22 1,000 3,088E-03 0,03214205 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 1,000 3,088E-03 0,03199727 ! regulation of cyclase activity GO:0031279 132 78 2,000 3,195E-03 0,03295279 ! regulation of cAMP biosynthetic process GO:0030817 136 79 2,000 3,312E-03 0,03400943 ! regulation of lyase activity GO:0051339 133 79 2,000 3,312E-03 0,03385827 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 3,374E-03 0,03434079 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 3,374E-03 0,03418951 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 3,374E-03 0,03403955 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 3,374E-03 0,03389091 ! osteoblast differentiation GO:0001649 40 23 1,000 3,374E-03 0,03374356 ! interaction with host GO:0051701 37 23 1,000 3,374E-03 0,03359748 ! cellular response to oxidative stress GO:0034599 33 23 1,000 3,374E-03 0,03345267 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 3,374E-03 0,03330909 ! alcohol catabolic process GO:0046164 104 80 2,000 3,432E-03 0,03373399 ! regulation of cAMP metabolic process GO:0030814 141 81 2,000 3,555E-03 0,0347891 ! pyruvate metabolic process GO:0006090 29 24 1,000 3,672E-03 0,0357882 ! neural crest cell development GO:0014032 39 24 1,000 3,672E-03 0,03563719 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 1,000 3,672E-03 0,03548746 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 3,672E-03 0,03533897 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 2,000 3,807E-03 0,03648796 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 1,000 3,982E-03 0,03800072 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 3,982E-03 0,03784369 GO:0045936|negative regulation of phosphate metabolic process, ! iron ion homeostasis GO:0055072 39 25 1,000 3,982E-03 0,03768795 ! regulation of chromosome organization GO:0033044 35 25 1,000 3,982E-03 0,0375335 ! positive regulation of nuclear division GO:0051785 39 25 1,000 3,982E-03 0,0373803 GO:0045840|positive regulation of mitosis, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 2,000 4,207E-03 0,03933317 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 4,303E-03 0,04006998 ! regulation of nucleotide metabolic process GO:0006140 150 89 2,000 4,631E-03 0,04294896 ! cofactor catabolic process GO:0051187 45 27 1,000 4,636E-03 0,04282387 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 4,636E-03 0,04265257 ! leukocyte differentiation GO:0002521 143 90 2,000 4,778E-03 0,0437817 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 4,981E-03 0,0454585 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 4,981E-03 0,04527882 ! neural tube formation GO:0001841 41 28 1,000 4,981E-03 0,04510056 ! placenta development GO:0001890 37 28 1,000 4,981E-03 0,04492369 ! regulation of B cell activation GO:0050864 42 28 1,000 4,981E-03 0,04474821 ! carbohydrate catabolic process GO:0016052 121 93 2,000 5,235E-03 0,04685407 ! mismatch repair GO:0006298 34 29 1,000 5,337E-03 0,04757471 ! angiogenesis GO:0001525 149 95 2,000 5,555E-03 0,04932668 ! collagen metabolic process GO:0032963 40 30 1,000 5,704E-03 0,05045823 ! spindle organization GO:0007051 37 30 1,000 5,704E-03 0,0502649 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 5,704E-03 0,05007305 ! response to light stimulus GO:0009416 153 96 2,000 5,718E-03 0,05000966 ! DNA damage checkpoint GO:0000077 53 31 1,000 6,083E-03 0,05299216 ! segmentation GO:0035282 41 31 1,000 6,083E-03 0,05279219 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 6,083E-03 0,05259372 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 6,083E-03 0,05239674 ! regulation of muscle development GO:0048634 48 32 1,000 6,472E-03 0,05554645 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 6,472E-03 0,05533996 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 6,472E-03 0,055135 ! meiosis I GO:0007127 52 32 1,000 6,472E-03 0,05493155 ! calcium-mediated signaling GO:0019722 50 32 1,000 6,472E-03 0,05472959 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 6,472E-03 0,05452912 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 6,873E-03 0,05769523 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 6,873E-03 0,05748543 ! sister chromatid segregation GO:0000819 46 33 1,000 6,873E-03 0,05727715 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 1,000 6,873E-03 0,05707037 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 7,285E-03 0,06027289 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 7,285E-03 0,06005686 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 7,285E-03 0,05984237 ! DNA integrity checkpoint GO:0031570 57 34 1,000 7,285E-03 0,05962941 ! aerobic respiration GO:0009060 47 34 1,000 7,285E-03 0,05941796 ! embryonic organ development GO:0048568 45 34 1,000 7,285E-03 0,059208 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 7,708E-03 0,06242381 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 8,142E-03 0,06570453 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 8,142E-03 0,0654748 ! neural tube development GO:0021915 50 36 1,000 8,142E-03 0,06524666 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 8,586E-03 0,06856929 ! mesenchymal cell development GO:0014031 64 38 1,000 9,041E-03 0,07195384 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 9,507E-03 0,07539899 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 9,507E-03 0,07513989 ! regulation of actin filament polymerization GO:0030833 59 40 1,000 9,983E-03 0,07863324 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 9,983E-03 0,07836487 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 9,983E-03 0,07809832 ! JAK-STAT cascade GO:0007259 53 40 1,000 9,983E-03 0,07783358 ! glucose transport GO:0015758 52 41 1,000 0,01046959 0,08135158 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01046959 0,08107767 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,01096652 0,08464093 ! hexose transport GO:0008645 54 42 1,000 0,01096652 0,08435785 GO:0015749|monosaccharide transport, ! positive regulation of binding GO:0051099 59 43 1,000 0,0114737 0,08796503 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,0114737 0,08767279 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,01199105 0,09132255 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,01199105 0,09102116 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,01251848 0,09471222 ! histone modification GO:0016570 68 46 1,000 0,01305593 0,09845455 ! covalent chromatin modification GO:0016569 75 47 1,000 0,0136033 0,10224702 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,0136033 0,10191397 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,0136033 0,10158308 ! regulation of protein polymerization GO:0032271 71 47 1,000 0,0136033 0,10125433 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,01416052 0,1050619 ! regulation of DNA replication GO:0006275 75 48 1,000 0,01416052 0,10472408 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,01416052 0,10438843 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,01416052 0,10405492 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,0147275 0,1078766 ! regulation of actin filament length GO:0030832 72 50 1,000 0,01530417 0,11174475 ! membrane fusion GO:0006944 80 50 1,000 0,01530417 0,11139112 ! lipid modification GO:0030258 73 50 1,000 0,01530417 0,11103973 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,01530417 0,11069055 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01589045 0,11457065 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,01589045 0,11421262 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,01589045 0,11385682 ! regulation of cellular component size GO:0032535 74 52 1,000 0,01648626 0,11775901 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01648626 0,11739443 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,01709152 0,12132871 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,01709152 0,12095539 ! regulation of mitosis GO:0007088 84 54 1,000 0,01770616 0,12492075 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01770616 0,12453873 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,01770616 0,12415904 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,01770616 0,12378165 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01770616 0,12340656 ! mesoderm development GO:0007498 76 55 1,000 0,01833009 0,12736921 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01873669 0,12980239 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01873669 0,1294126 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01873669 0,12902513 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01873669 0,12863999 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01873669 0,12825713 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01873669 0,12787654 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01873669 0,12749821 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01873669 0,12712211 ! sleep GO:0030431 11 5 0,000 0,01873669 0,12674822 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01873669 0,12637653 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01873669 0,126007 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01873669 0,12563964 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01873669 0,1252744 ! tongue development GO:0043586 6 5 0,000 0,01873669 0,12491129 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01873669 0,12455027 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01873669 0,12419134 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01873669 0,12383447 ! cobalt ion transport GO:0006824 9 5 0,000 0,01873669 0,12347964 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01873669 0,12312684 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01873669 0,12277605 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01873669 0,12242726 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01873669 0,12208044 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01873669 0,12173558 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01873669 0,12139266 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01873669 0,12105167 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01873669 0,12071259 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01873669 0,12037541 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01873669 0,1200401 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01873669 0,11970665 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01873669 0,11937506 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01873669 0,11904529 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01873669 0,11871734 ! malate metabolic process GO:0006108 7 5 0,000 0,01873669 0,1183912 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01873669 0,11806684 ! behavioral response to pain GO:0048266 7 5 0,000 0,01873669 0,11774425 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01873669 0,11742342 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01873669 0,11710433 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01873669 0,11678698 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01873669 0,11647134 ! mating behavior GO:0007617 6 5 0,000 0,01873669 0,1161574 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01873669 0,11584515 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01873669 0,11553457 ! rhythmic behavior GO:0007622 12 5 0,000 0,01873669 0,11522566 ! copulation GO:0007620 7 5 0,000 0,01873669 0,11491839 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01873669 0,11461275 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01873669 0,11430874 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01873669 0,11400634 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01873669 0,11370553 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01873669 0,1134063 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01873669 0,11310865 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01873669 0,11281255 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01873669 0,112518 ! response to protozoan GO:0001562 9 5 0,000 0,01873669 0,11222499 ! lymph vessel development GO:0001945 7 5 0,000 0,01873669 0,11193349 ! endochondral ossification GO:0001958 12 5 0,000 0,01873669 0,11164351 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01873669 0,11135503 ! parathyroid gland development GO:0060017 8 5 0,000 0,01873669 0,11106803 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01873669 0,11078251 ! anagen GO:0042640 6 5 0,000 0,01873669 0,11049845 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01873669 0,11021584 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01873669 0,10993468 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01873669 0,10965495 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01873669 0,10937664 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01873669 0,10909973 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01873669 0,10882423 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01873669 0,10855011 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01873669 0,10827737 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01873669 0,108006 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01873669 0,10773599 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01873669 0,10746732 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01873669 0,10719999 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01873669 0,10693398 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01873669 0,10666929 ! ovulation GO:0030728 6 5 0,000 0,01873669 0,10640591 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01873669 0,10614383 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01873669 0,10588303 GO:0030033|microvillus assembly, ! response to pH GO:0009268 9 5 0,000 0,01873669 0,10562352 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01873669 0,10536527 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01873669 0,10510828 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01873669 0,10485254 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01873669 0,10459805 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01873669 0,10434478 ! polyol catabolic process GO:0046174 7 5 0,000 0,01873669 0,10409274 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01873669 0,10384192 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01873669 0,1035923 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01873669 0,10334387 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01873669 0,10309664 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01873669 0,10285058 ! urea metabolic process GO:0019627 6 5 0,000 0,01873669 0,1026057 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01873669 0,10236198 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01873669 0,10211942 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01873669 0,101878 ! neutrophil activation GO:0042119 5 5 0,000 0,01873669 0,10163772 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01873669 0,10139858 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01873669 0,10116055 ! response to food GO:0032094 5 5 0,000 0,01873669 0,10092364 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01873669 0,10068784 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01873669 0,10045314 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01873669 0,10021952 ! forebrain neuron development GO:0021884 7 5 0,000 0,01873669 0,099987 ! melanosome organization GO:0032438 7 5 0,000 0,01873669 0,09975554 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01873669 0,09952516 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01873669 0,09929584 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01873669 0,09906757 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01873669 0,09884036 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01873669 0,09861418 ! nucleoside transport GO:0015858 6 5 0,000 0,01873669 0,09838903 ! nucleoside salvage GO:0043174 7 5 0,000 0,01873669 0,09816491 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01873669 0,09794181 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01873669 0,09771972 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01873669 0,09749863 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01873669 0,09727854 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01873669 0,09705945 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01873669 0,09684134 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01873669 0,0966242 ! depyrimidination GO:0045008 8 5 0,000 0,01873669 0,09640804 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01873669 0,09619285 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01873669 0,09597861 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01873669 0,09576532 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01873669 0,09555298 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01873669 0,09534158 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01873669 0,09513111 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01873669 0,09492158 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01873669 0,09471296 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01873669 0,09450525 ! monocyte differentiation GO:0030224 8 5 0,000 0,01873669 0,09429846 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01873669 0,09409257 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01873669 0,09388757 ! centrosome duplication GO:0051298 5 5 0,000 0,01873669 0,09368347 ! response to UV-C GO:0010225 6 5 0,000 0,01873669 0,09348025 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01873669 0,09327791 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01873669 0,09307645 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01873669 0,09287585 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01873669 0,09267612 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01873669 0,09247724 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01873669 0,09227922 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01873669 0,09208204 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01873669 0,0918857 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01873669 0,0916902 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01873669 0,09149553 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01873669 0,09130168 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01873669 0,09110866 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01873669 0,09091645 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01873669 0,09072504 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01873669 0,09053444 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01873669 0,09034464 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01873669 0,09015564 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01873669 0,08996742 ! neural tube patterning GO:0021532 6 5 0,000 0,01873669 0,08977999 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01873669 0,08959334 ! histone demethylation GO:0016577 9 5 0,000 0,01873669 0,08940746 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01873669 0,08922235 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01873669 0,08903801 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01873669 0,08885442 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01873669 0,08867159 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01873669 0,08848952 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01873669 0,08830819 ! transcription termination GO:0006353 8 5 0,000 0,01873669 0,0881276 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01873669 0,08794775 ! plasminogen activation GO:0031639 5 5 0,000 0,01873669 0,08776863 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01873669 0,08759023 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01873669 0,08741257 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01873669 0,08723562 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01873669 0,08705938 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01873669 0,08688386 ! apical protein localization GO:0045176 6 5 0,000 0,01873669 0,08670904 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01873669 0,08653493 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01873669 0,08636151 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01873669 0,08618879 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01873669 0,08601676 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01873669 0,08584541 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01873669 0,08567474 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01873669 0,08550475 ! glial cell migration GO:0008347 10 5 0,000 0,01873669 0,08533544 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01873669 0,08516679 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01873669 0,08499881 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01873669 0,08483149 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01873669 0,08466482 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01873669 0,08449881 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01873669 0,08433345 ! neural plate development GO:0001840 6 5 0,000 0,01873669 0,08416874 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01873669 0,08400467 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01873669 0,08384124 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01873669 0,08367844 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01873669 0,08351627 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01873669 0,08335473 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01873669 0,08319381 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01873669 0,08303352 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01873669 0,08287384 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01873669 0,08271477 ! spindle assembly GO:0051225 5 5 0,000 0,01873669 0,08255631 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01873669 0,08239846 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01873669 0,08224121 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01873669 0,08208456 ! organ regeneration GO:0031100 7 5 0,000 0,01873669 0,08192851 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01873669 0,08177305 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01873669 0,08161817 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01873669 0,08146388 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01873669 0,08131018 GO:0055081|anion homeostasis, ! carbohydrate transport GO:0008643 74 57 1,000 0,01960554 0,08492043 ! chromosome segregation GO:0007059 83 57 1,000 0,01960554 0,0847608 ! coenzyme biosynthetic process GO:0009108 67 57 1,000 0,01960554 0,08460178 ! viral reproductive process GO:0022415 87 58 1,000 0,02025691 0,08724886 ! actin filament organization GO:0007015 95 59 1,000 0,02091727 0,0899247 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,02158654 0,09262883 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,02158654 0,09245634 GO:0035113|embryonic appendage morphogenesis, ! meiosis GO:0007126 96 61 1,000 0,02226467 0,09518351 GO:0051327|M phase of meiotic cell cycle, ! tRNA transcription GO:0009304 11 6 0,000 0,02244233 0,09576504 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02244233 0,09558769 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02244233 0,09541101 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02244233 0,09523497 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02244233 0,09505959 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02244233 0,09488484 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02244233 0,09471074 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02244233 0,09453728 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02244233 0,09436445 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02244233 0,09419225 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02244233 0,09402068 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02244233 0,09384974 ! prostate gland development GO:0030850 9 6 0,000 0,02244233 0,09367941 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02244233 0,0935097 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02244233 0,09334061 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02244233 0,09317212 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02244233 0,09300424 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02244233 0,09283697 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02244233 0,0926703 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02244233 0,09250422 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02244233 0,09233874 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02244233 0,09217385 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02244233 0,09200955 ! neuron adhesion GO:0007158 9 6 0,000 0,02244233 0,09184583 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02244233 0,09168269 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02244233 0,09152013 ! signal peptide processing GO:0006465 8 6 0,000 0,02244233 0,09135815 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02244233 0,09119674 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02244233 0,0910359 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02244233 0,09087562 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02244233 0,09071591 ! opsonization GO:0008228 8 6 0,000 0,02244233 0,09055676 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02244233 0,09039817 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02244233 0,09024013 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02244233 0,09008264 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02244233 0,08992571 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02244233 0,08976931 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02244233 0,08961346 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02244233 0,08945815 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02244233 0,08930338 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02244233 0,08914915 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02244233 0,08899544 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02244233 0,08884226 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02244233 0,08868961 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02244233 0,08853749 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02244233 0,08838588 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02244233 0,08823479 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02244233 0,08808422 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02244233 0,08793417 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02244233 0,08778462 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02244233 0,08763558 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02244233 0,08748704 ! thymic T cell selection GO:0045061 12 6 0,000 0,02244233 0,08733901 ! protein lipoylation GO:0009249 10 6 0,000 0,02244233 0,08719148 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02244233 0,08704444 ! pigment granule organization GO:0048753 11 6 0,000 0,02244233 0,0868979 ! drug transport GO:0015893 6 6 0,000 0,02244233 0,08675186 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02244233 0,0866063 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02244233 0,08646123 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02244233 0,08631665 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02244233 0,08617255 ! histidine metabolic process GO:0006547 6 6 0,000 0,02244233 0,08602892 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02244233 0,08588578 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02244233 0,08574311 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02244233 0,08560092 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02244233 0,0854592 ! adenohypophysis development GO:0021984 10 6 0,000 0,02244233 0,08531794 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02244233 0,08517715 ! hyperosmotic response GO:0006972 8 6 0,000 0,02244233 0,08503683 ! microtubule nucleation GO:0007020 10 6 0,000 0,02244233 0,08489697 ! ER overload response GO:0006983 7 6 0,000 0,02244233 0,08475756 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02244233 0,08461861 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02244233 0,08448012 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02244233 0,08434208 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02244233 0,08420449 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02244233 0,08406735 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02244233 0,08393066 ! response to dietary excess GO:0002021 7 6 0,000 0,02244233 0,08379441 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02244233 0,0836586 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02244233 0,08352323 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02244233 0,0833883 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02244233 0,0832538 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02244233 0,08311973 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02244233 0,0829861 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02244233 0,0828529 ! neuron apoptosis GO:0051402 8 6 0,000 0,02244233 0,08272012 ! organic alcohol transport GO:0015850 9 6 0,000 0,02244233 0,08258777 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02244233 0,08245584 ! carnitine transport GO:0015879 8 6 0,000 0,02244233 0,08232433 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02244233 0,08219324 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02244233 0,08206257 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02244233 0,08193231 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02244233 0,08180246 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02244233 0,08167303 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02244233 0,081544 ! parturition GO:0007567 12 6 0,000 0,02244233 0,08141539 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02244233 0,08128717 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02244233 0,08115936 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02244233 0,08103195 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02244233 0,08090495 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02244233 0,08077833 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02244233 0,08065212 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02244233 0,08052629 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02244233 0,08040086 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02244233 0,08027582 ! astrocyte development GO:0014002 14 6 0,000 0,02244233 0,08015117 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02244233 0,08002691 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02244233 0,07990303 ! interaction with symbiont GO:0051702 8 6 0,000 0,02244233 0,07977953 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02244233 0,07965641 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02244233 0,07953367 ! eating behavior GO:0042755 6 6 0,000 0,02244233 0,07941132 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02244233 0,07928933 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02244233 0,07916772 ! response to copper ion GO:0046688 9 6 0,000 0,02244233 0,07904649 ! DNA topological change GO:0006265 8 6 0,000 0,02244233 0,07892562 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02244233 0,07880512 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02244233 0,07868499 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02244233 0,07856523 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02244233 0,07844583 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02244233 0,07832679 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02244233 0,07820811 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02244233 0,0780898 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02244233 0,07797184 ! hair follicle maturation GO:0048820 7 6 0,000 0,02244233 0,07785423 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02244233 0,07773698 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02244233 0,07762008 ! Schwann cell development GO:0014044 14 6 0,000 0,02244233 0,07750354 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02244233 0,07738734 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02244233 0,07727149 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02244233 0,07715599 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02244233 0,07704083 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02244233 0,07692601 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02244233 0,07681154 ! histone ubiquitination GO:0016574 7 6 0,000 0,02244233 0,07669741 ! regulation of meiosis GO:0040020 10 6 0,000 0,02244233 0,07658361 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02244233 0,07647016 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02244233 0,07635703 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02244233 0,07624425 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02244233 0,07613179 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02244233 0,07601967 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02244233 0,07590787 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02244233 0,07579641 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02244233 0,07568527 ! receptor internalization GO:0031623 9 6 0,000 0,02244233 0,07557446 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02244233 0,07546397 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02244233 0,0753538 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02244233 0,07524396 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02244233 0,07513443 ! protein deubiquitination GO:0016579 8 6 0,000 0,02244233 0,07502523 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02244233 0,07491634 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02244233 0,07480776 ! axonal fasciculation GO:0007413 9 6 0,000 0,02244233 0,0746995 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02244233 0,07459155 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02244233 0,07448392 ! midbrain development GO:0030901 6 6 0,000 0,02244233 0,07437659 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02244233 0,07426958 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02244233 0,07416287 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02244233 0,07405646 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02244233 0,07395037 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02244233 0,07384457 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02244233 0,07373908 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02244233 0,07363389 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02244233 0,073529 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02244233 0,0734244 ! adult feeding behavior GO:0008343 6 6 0,000 0,02244233 0,07332011 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02244233 0,07321611 ! blastocyst growth GO:0001832 15 6 0,000 0,02244233 0,0731124 ! pigment granule transport GO:0051904 12 6 0,000 0,02244233 0,07300899 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02244233 0,07290587 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02244233 0,07280304 ! catecholamine transport GO:0051937 7 6 0,000 0,02244233 0,0727005 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02244233 0,07259825 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02244233 0,07249629 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02244233 0,07239461 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02244233 0,07229321 ! protein prenylation GO:0018342 10 6 0,000 0,02244233 0,0721921 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02244233 0,07209128 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02244233 0,07199073 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02244233 0,07189047 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02244233 0,07179048 ! amine catabolic process GO:0009310 90 62 1,000 0,02295155 0,07331747 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,02295155 0,07321578 ! meiotic cell cycle GO:0051321 97 62 1,000 0,02295155 0,07311437 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02364714 0,07522603 GO:0090046|regulation of transcription regulator activity, ! viral reproduction GO:0016032 92 63 1,000 0,02364714 0,07512213 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02364714 0,07501851 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,02435135 0,07714614 ! negative regulation of cell size GO:0045792 108 64 1,000 0,02435135 0,07704003 ! appendage morphogenesis GO:0035107 93 64 1,000 0,02435135 0,0769342 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,02435135 0,07682867 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,02435135 0,07672342 ! adaptive immune response GO:0002250 94 64 1,000 0,02435135 0,07661847 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 1,000 0,0250641 0,07875333 GO:0060173|limb development, ! protein oligomerization GO:0051259 100 65 1,000 0,0250641 0,07864589 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,02578534 0,08079874 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,02578534 0,08068881 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02613418 0,08166931 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02613418 0,0815585 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02613418 0,08144799 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02613418 0,08133777 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02613418 0,08122786 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02613418 0,08111824 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02613418 0,08100891 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02613418 0,08089989 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02613418 0,08079115 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02613418 0,0806827 ! reproductive behavior GO:0019098 12 7 0,000 0,02613418 0,08057455 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02613418 0,08046669 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02613418 0,08035911 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02613418 0,08025182 ! oligopeptide transport GO:0006857 11 7 0,000 0,02613418 0,08014482 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02613418 0,0800381 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02613418 0,07993167 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02613418 0,07982552 ! RNA methylation GO:0001510 11 7 0,000 0,02613418 0,07971965 ! pericardium development GO:0060039 8 7 0,000 0,02613418 0,07961406 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02613418 0,07950875 ! fibril organization GO:0043206 13 7 0,000 0,02613418 0,07940372 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02613418 0,07929896 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02613418 0,07919449 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02613418 0,07909028 ! lipoprotein transport GO:0042953 9 7 0,000 0,02613418 0,07898635 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02613418 0,0788827 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02613418 0,07877931 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02613418 0,0786762 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02613418 0,07857335 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02613418 0,07847078 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02613418 0,07836847 ! chemosensory behavior GO:0007635 9 7 0,000 0,02613418 0,07826643 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02613418 0,07816465 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02613418 0,07806314 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02613418 0,07796189 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02613418 0,0778609 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02613418 0,07776017 ! reflex GO:0060004 12 7 0,000 0,02613418 0,07765971 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02613418 0,0775595 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02613418 0,07745955 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02613418 0,07735986 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02613418 0,07726043 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02613418 0,07716125 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02613418 0,07706233 ! spinal cord patterning GO:0021511 7 7 0,000 0,02613418 0,07696366 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02613418 0,07686524 ! adrenal gland development GO:0030325 17 7 0,000 0,02613418 0,07676707 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02613418 0,07666915 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02613418 0,07657148 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02613418 0,07647406 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02613418 0,07637689 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02613418 0,07627997 ! endosome organization GO:0007032 10 7 0,000 0,02613418 0,07618329 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02613418 0,07608685 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02613418 0,07599066 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02613418 0,07589472 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02613418 0,07579901 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02613418 0,07570354 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02613418 0,07560832 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02613418 0,07551334 ! galactose metabolic process GO:0006012 10 7 0,000 0,02613418 0,07541859 ! vesicle fusion GO:0006906 15 7 0,000 0,02613418 0,07532408 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02613418 0,07522981 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02613418 0,07513577 ! organ growth GO:0035265 11 7 0,000 0,02613418 0,07504197 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02613418 0,0749484 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02613418 0,07485506 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02613418 0,07476196 ! retinol metabolic process GO:0042572 9 7 0,000 0,02613418 0,07466909 ! behavioral fear response GO:0001662 13 7 0,000 0,02613418 0,07457645 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02613418 0,07448403 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02613418 0,07439185 ! rRNA modification GO:0000154 12 7 0,000 0,02613418 0,07429989 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02613418 0,07420817 ! response to UV-B GO:0010224 11 7 0,000 0,02613418 0,07411666 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,02613418 0,07402539 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02613418 0,07393434 ! intermediate filament organization GO:0045109 11 7 0,000 0,02613418 0,07384351 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02613418 0,0737529 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02613418 0,07366252 ! fibrinolysis GO:0042730 9 7 0,000 0,02613418 0,07357236 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02613418 0,07348241 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02613418 0,07339269 ! B cell lineage commitment GO:0002326 17 7 0,000 0,02613418 0,07330319 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02613418 0,0732139 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02613418 0,07312484 ! response to tropane GO:0014073 13 7 0,000 0,02613418 0,07303598 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02613418 0,07294735 ! melanosome localization GO:0032400 10 7 0,000 0,02613418 0,07285893 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02613418 0,07277072 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02613418 0,07268273 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02613418 0,07259495 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02613418 0,07250738 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02613418 0,07242002 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02613418 0,07233287 ! mast cell activation GO:0045576 9 7 0,000 0,02613418 0,07224593 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02613418 0,0721592 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02613418 0,07207268 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02613418 0,07198636 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02613418 0,07190026 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02613418 0,07181435 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02613418 0,07172866 ! T cell lineage commitment GO:0002360 12 7 0,000 0,02613418 0,07164316 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02613418 0,07155787 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02613418 0,07147279 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02613418 0,0713879 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02613418 0,07130322 ! response to tumor cell GO:0002347 12 7 0,000 0,02613418 0,07121874 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02613418 0,07113446 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02613418 0,07105037 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02613418 0,07096649 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02613418 0,0708828 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02613418 0,07079931 ! diuresis GO:0030146 12 7 0,000 0,02613418 0,07071602 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02613418 0,07063292 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02613418 0,07055002 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02613418 0,07046731 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02613418 0,07038479 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02613418 0,07030247 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02613418 0,07022034 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02613418 0,07013841 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02613418 0,07005666 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02613418 0,0699751 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02613418 0,06989374 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02613418 0,06981256 ! lymph node development GO:0048535 9 7 0,000 0,02613418 0,06973157 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02613418 0,06965077 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02613418 0,06957016 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02613418 0,06948973 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02613418 0,06940949 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02613418 0,06932943 ! ATP catabolic process GO:0006200 10 7 0,000 0,02613418 0,06924956 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02613418 0,06916987 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02613418 0,06909036 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02613418 0,06901104 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02613418 0,0689319 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02613418 0,06885294 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02613418 0,06877416 ! muscle adaptation GO:0043500 12 7 0,000 0,02613418 0,06869556 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02613418 0,06861714 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02613418 0,0685389 ! retina homeostasis GO:0001895 9 7 0,000 0,02613418 0,06846084 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02613418 0,06838295 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02613418 0,06830524 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02613418 0,06822771 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02613418 0,06815036 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02613418 0,06807318 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02613418 0,06799617 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02613418 0,06791934 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,02799918 0,0726841 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,0298123 0,0773036 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,0298123 0,07721654 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,0298123 0,07712969 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,0298123 0,07704302 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,0298123 0,07695655 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,0298123 0,07687028 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,0298123 0,0767842 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,0298123 0,07669831 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,0298123 0,07661261 ! phosphate transport GO:0006817 10 8 0,000 0,0298123 0,07652711 ! N-glycan processing GO:0006491 12 8 0,000 0,0298123 0,0764418 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,0298123 0,07635667 ! UTP metabolic process GO:0046051 8 8 0,000 0,0298123 0,07627174 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,0298123 0,07618699 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,0298123 0,07610243 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,0298123 0,07601806 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,0298123 0,07593388 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,0298123 0,07584988 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0298123 0,07576607 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,0298123 0,07568244 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,0298123 0,075599 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,0298123 0,07551574 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,0298123 0,07543266 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,0298123 0,07534977 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0298123 0,07526706 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,0298123 0,07518453 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,0298123 0,07510218 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,0298123 0,07502001 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,0298123 0,07493802 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,0298123 0,07485621 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,0298123 0,07477458 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,0298123 0,07469313 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,0298123 0,07461185 ! astrocyte differentiation GO:0048708 16 8 0,000 0,0298123 0,07453075 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,0298123 0,07444983 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,0298123 0,07436908 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,0298123 0,07428851 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,0298123 0,07420811 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,0298123 0,07412788 ! melanin metabolic process GO:0006582 12 8 0,000 0,0298123 0,07404783 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,0298123 0,07396795 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0298123 0,07388824 ! macrophage activation GO:0042116 12 8 0,000 0,0298123 0,07380871 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,0298123 0,07372934 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,0298123 0,07365015 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,0298123 0,07357113 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,0298123 0,07349227 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,0298123 0,07341359 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,0298123 0,07333507 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,0298123 0,07325672 ! ruffle organization GO:0031529 11 8 0,000 0,0298123 0,07317854 ! osteoblast development GO:0002076 13 8 0,000 0,0298123 0,07310052 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,0298123 0,07302267 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,0298123 0,07294499 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,0298123 0,07286747 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,0298123 0,07279012 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,0298123 0,07271293 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,0298123 0,0726359 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,0298123 0,07255904 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,0298123 0,07248234 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,0298123 0,0724058 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,0298123 0,07232942 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,0298123 0,0722532 ! oligodendrocyte development GO:0014003 8 8 0,000 0,0298123 0,07217715 ! segment specification GO:0007379 10 8 0,000 0,0298123 0,07210125 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,0298123 0,07202552 ! cellular extravasation GO:0045123 11 8 0,000 0,0298123 0,07194994 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,0298123 0,07187452 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,0298123 0,07179926 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,0298123 0,07172415 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,0298123 0,07164921 ! snRNA metabolic process GO:0016073 10 8 0,000 0,0298123 0,07157442 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,0298123 0,07149978 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,0298123 0,0714253 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,0298123 0,07135098 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,0298123 0,07127681 ! nucleosome disassembly GO:0006337 12 8 0,000 0,0298123 0,07120279 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,0298123 0,07112893 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,0298123 0,07105522 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,0298123 0,07098167 ! icosanoid secretion GO:0032309 12 8 0,000 0,0298123 0,07090826 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,0298123 0,07083501 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0298123 0,07076191 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,0298123 0,07068896 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,0298123 0,07061616 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,0298123 0,07054351 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,0298123 0,07047101 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,0298123 0,07039866 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,0298123 0,07032645 ! sterol catabolic process GO:0016127 9 8 0,000 0,0298123 0,0702544 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,0298123 0,07018249 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,0298123 0,07011073 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,0298123 0,07003911 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,0298123 0,06996764 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0298123 0,06989632 ! prophase GO:0051324 11 8 0,000 0,0298123 0,06982514 ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,0298123 0,06975411 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,0298123 0,06968322 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,0298123 0,06961248 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,0298123 0,06954188 ! hormone catabolic process GO:0042447 13 8 0,000 0,0298123 0,06947142 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,0298123 0,0694011 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,0298123 0,06933093 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,0298123 0,0692609 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,0298123 0,06919101 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,0298123 0,06912126 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,0298123 0,06905165 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,0298123 0,06898218 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0298123 0,06891285 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,0298123 0,06884366 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,0298123 0,06877461 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,0298123 0,0687057 ! lamellipodium assembly GO:0030032 9 8 0,000 0,0298123 0,06863693 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0298123 0,06856829 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,0298123 0,06849979 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,03028675 0,06952047 ! tube morphogenesis GO:0035239 118 73 1,000 0,03106532 0,07123653 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,03106532 0,07116558 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,03185181 0,07289469 ! cofactor biosynthetic process GO:0051188 92 75 1,000 0,03264614 0,07463829 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03347674 0,07646127 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03347674 0,07638541 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03347674 0,07630971 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03347674 0,07623416 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03347674 0,07615875 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03347674 0,0760835 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03347674 0,07600839 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03347674 0,07593343 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03347674 0,07585862 ! GTP metabolic process GO:0046039 9 9 0,000 0,03347674 0,07578395 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03347674 0,07570944 ! social behavior GO:0035176 14 9 0,000 0,03347674 0,07563507 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03347674 0,07556084 ! artery development GO:0060840 19 9 0,000 0,03347674 0,07548676 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03347674 0,07541283 ! response to pain GO:0048265 16 9 0,000 0,03347674 0,07533904 ! protein complex disassembly GO:0043241 17 9 0,000 0,03347674 0,07526539 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03347674 0,07519189 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03347674 0,07511853 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03347674 0,07504532 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03347674 0,07497225 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03347674 0,07489932 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03347674 0,07482653 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03347674 0,07475388 ! protein targeting to ER GO:0045047 19 9 0,000 0,03347674 0,07468137 ! T cell selection GO:0045058 18 9 0,000 0,03347674 0,07460901 ! endoderm development GO:0007492 12 9 0,000 0,03347674 0,07453678 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03347674 0,0744647 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03347674 0,07439275 ! arginine catabolic process GO:0006527 10 9 0,000 0,03347674 0,07432094 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03347674 0,07424927 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03347674 0,07417774 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03347674 0,07410635 ! V(D)J recombination GO:0033151 12 9 0,000 0,03347674 0,07403509 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03347674 0,07396397 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03347674 0,07389299 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03347674 0,07382215 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03347674 0,07375143 ! mannose metabolic process GO:0006013 9 9 0,000 0,03347674 0,07368086 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03347674 0,07361042 ! receptor clustering GO:0043113 15 9 0,000 0,03347674 0,07354011 ! epithelial cell development GO:0002064 10 9 0,000 0,03347674 0,07346994 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03347674 0,0733999 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03347674 0,07333 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03347674 0,07326023 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03347674 0,07319059 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03347674 0,07312108 ! motor axon guidance GO:0008045 14 9 0,000 0,03347674 0,07305171 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03347674 0,07298246 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03347674 0,07291335 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03347674 0,07284437 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03347674 0,07277552 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03347674 0,0727068 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03347674 0,07263821 ! DNA ligation GO:0006266 14 9 0,000 0,03347674 0,07256974 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03347674 0,07250141 ! response to amine stimulus GO:0014075 13 9 0,000 0,03347674 0,07243321 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03347674 0,07236513 ! erythrocyte development GO:0048821 11 9 0,000 0,03347674 0,07229718 ! renal water homeostasis GO:0003091 14 9 0,000 0,03347674 0,07222936 ! postreplication repair GO:0006301 11 9 0,000 0,03347674 0,07216167 ! mRNA cleavage GO:0006379 13 9 0,000 0,03347674 0,0720941 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03347674 0,07202666 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03347674 0,07195934 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03347674 0,07189215 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03347674 0,07182509 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03347674 0,07175815 ! acid secretion GO:0046717 14 9 0,000 0,03347674 0,07169134 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03347674 0,07162465 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03347674 0,07155808 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03347674 0,07149164 ! purine base metabolic process GO:0006144 18 9 0,000 0,03347674 0,07142532 ! oocyte differentiation GO:0009994 12 9 0,000 0,03347674 0,07135913 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03347674 0,07129305 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03347674 0,0712271 ! spleen development GO:0048536 15 9 0,000 0,03347674 0,07116127 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03347674 0,07109557 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03347674 0,07102998 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03347674 0,07096451 ! detection of calcium ion GO:0005513 13 9 0,000 0,03347674 0,07089917 ! blastocyst formation GO:0001825 12 9 0,000 0,03347674 0,07083394 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03347674 0,07076884 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03347674 0,07070385 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03347674 0,07063899 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03347674 0,07057424 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03347674 0,07050961 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03347674 0,0704451 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03347674 0,07038071 ! prepulse inhibition GO:0060134 14 9 0,000 0,03347674 0,07031644 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03347674 0,07025228 ! insulin secretion GO:0030073 17 9 0,000 0,03347674 0,07018824 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03347674 0,07012431 ! response to nicotine GO:0035094 16 9 0,000 0,03347674 0,07006051 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03347674 0,06999682 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03347674 0,06993324 ! regulation of DNA binding GO:0051101 119 77 1,000 0,03425805 0,07150048 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,0350755 0,07314022 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,0350755 0,07307397 ! cellular respiration GO:0045333 107 79 1,000 0,03590052 0,07472507 ! forebrain development GO:0030900 131 80 1,000 0,03673305 0,0763888 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03712754 0,07713943 ! neuron fate specification GO:0048665 11 10 0,000 0,03712754 0,07706981 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03712754 0,07700032 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03712754 0,07693095 ! thyroid gland development GO:0030878 19 10 0,000 0,03712754 0,0768617 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03712754 0,07679258 ! synapsis GO:0007129 13 10 0,000 0,03712754 0,07672359 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03712754 0,07665471 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03712754 0,07658597 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03712754 0,07651734 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03712754 0,07644884 ! sulfate transport GO:0008272 12 10 0,000 0,03712754 0,07638046 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03712754 0,0763122 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,03712754 0,07624406 ! phospholipid efflux GO:0033700 16 10 0,000 0,03712754 0,07617605 ! hippocampus development GO:0021766 19 10 0,000 0,03712754 0,07610816 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,03712754 0,07604038 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03712754 0,07597273 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03712754 0,0759052 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03712754 0,07583779 ! pathogenesis GO:0009405 13 10 0,000 0,03712754 0,0757705 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03712754 0,07570333 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03712754 0,07563627 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03712754 0,07556934 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03712754 0,07550252 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03712754 0,07543582 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03712754 0,07536924 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03712754 0,07530278 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03712754 0,07523643 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03712754 0,0751702 ! response to X-ray GO:0010165 16 10 0,000 0,03712754 0,07510409 ! B cell proliferation GO:0042100 14 10 0,000 0,03712754 0,07503809 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03712754 0,07497221 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03712754 0,07490645 ! forebrain cell migration GO:0021885 17 10 0,000 0,03712754 0,0748408 ! lipid digestion GO:0044241 15 10 0,000 0,03712754 0,07477526 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03712754 0,07470984 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03712754 0,07464454 ! UV protection GO:0009650 14 10 0,000 0,03712754 0,07457935 ! entry into host cell GO:0030260 20 10 0,000 0,03712754 0,07451427 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03712754 0,0744493 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03712754 0,07438445 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03712754 0,07431971 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03712754 0,07425509 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03712754 0,07419057 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03712754 0,07412617 ! regulation of organ growth GO:0046620 11 10 0,000 0,03712754 0,07406188 ! response to dsRNA GO:0043331 18 10 0,000 0,03712754 0,07399771 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03712754 0,07393364 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03712754 0,07386968 ! embryonic axis specification GO:0000578 12 10 0,000 0,03712754 0,07380584 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03712754 0,0737421 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03712754 0,07367847 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03712754 0,07361496 ! cranial nerve development GO:0021545 12 10 0,000 0,03712754 0,07355155 ! fucose catabolic process GO:0019317 16 10 0,000 0,03712754 0,07348825 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03712754 0,07342507 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03712754 0,07336199 ! protein sumoylation GO:0016925 12 10 0,000 0,03712754 0,07329901 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03712754 0,07323615 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03712754 0,07317339 ! zymogen activation GO:0031638 14 10 0,000 0,03712754 0,07311075 ! salivary gland development GO:0007431 22 10 0,000 0,03712754 0,0730482 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03712754 0,07298577 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03712754 0,07292344 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03712754 0,07286122 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03712754 0,07279911 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03712754 0,0727371 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03712754 0,07267519 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03712754 0,07261339 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03712754 0,0725517 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03712754 0,07249011 ! detection of bacterium GO:0016045 10 10 0,000 0,03712754 0,07242863 ! embryonic gut development GO:0048566 11 10 0,000 0,03712754 0,07236725 ! activation of innate immune response GO:0002218 10 10 0,000 0,03712754 0,07230597 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03712754 0,0722448 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03712754 0,07218373 ! developmental induction GO:0031128 13 10 0,000 0,03712754 0,07212276 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03712754 0,0720619 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03712754 0,07200114 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03712754 0,07194048 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03712754 0,07187993 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,03757301 0,07268118 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,03757301 0,0726201 GO:0002696|positive regulation of leukocyte activation, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,03927498 0,0758459 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,04013686 0,07744529 ! rRNA transcription GO:0009303 17 11 0,000 0,04076477 0,07859092 ! respiratory burst GO:0045730 14 11 0,000 0,04076477 0,0785251 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04076477 0,07845939 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,04076477 0,07839379 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,04076477 0,07832829 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,04076477 0,07826291 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04076477 0,07819764 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04076477 0,07813247 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,04076477 0,07806742 ! mating GO:0007618 14 11 0,000 0,04076477 0,07800247 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04076477 0,07793763 ! T cell proliferation GO:0042098 20 11 0,000 0,04076477 0,0778729 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04076477 0,07780827 ! bone resorption GO:0045453 16 11 0,000 0,04076477 0,07774375 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04076477 0,07767934 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04076477 0,07761504 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,04076477 0,07755084 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,04076477 0,07748675 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04076477 0,07742276 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04076477 0,07735888 ! syncytium formation GO:0006949 15 11 0,000 0,04076477 0,07729511 ! plasma membrane organization GO:0007009 18 11 0,000 0,04076477 0,07723144 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04076477 0,07716787 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04076477 0,07710441 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04076477 0,07704106 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,04076477 0,07697781 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04076477 0,07691466 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04076477 0,07685161 ! adult heart development GO:0007512 11 11 0,000 0,04076477 0,07678867 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04076477 0,07672583 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04076477 0,0766631 ! temperature homeostasis GO:0001659 16 11 0,000 0,04076477 0,07660046 ! L-glutamate transport GO:0015813 16 11 0,000 0,04076477 0,07653793 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04076477 0,0764755 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04076477 0,07641318 ! stem cell development GO:0048864 29 11 0,000 0,04076477 0,07635095 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,04076477 0,07628883 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04076477 0,0762268 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,04076477 0,07616488 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,04076477 0,07610306 ! vasoconstriction GO:0042310 15 11 0,000 0,04076477 0,07604134 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04076477 0,07597971 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04076477 0,07591819 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,04076477 0,07585677 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04076477 0,07579545 ! ribosome assembly GO:0042255 13 11 0,000 0,04076477 0,07573422 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04076477 0,0756731 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,04076477 0,07561207 ! chromatin silencing GO:0006342 19 11 0,000 0,04076477 0,07555114 ! nucleosome positioning GO:0016584 13 11 0,000 0,04076477 0,07549031 ! T cell homeostasis GO:0043029 20 11 0,000 0,04076477 0,07542958 ! regulation of isotype switching GO:0045191 19 11 0,000 0,04076477 0,07536894 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04076477 0,07530841 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04076477 0,07524797 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04076477 0,07518762 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,04076477 0,07512738 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,04076477 0,07506723 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,04076477 0,07500717 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,04076477 0,07494722 ! male genitalia development GO:0030539 13 11 0,000 0,04076477 0,07488735 ! cholesterol efflux GO:0033344 19 11 0,000 0,04076477 0,07482759 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04076477 0,07476792 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04076477 0,07470834 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04076477 0,07464886 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04076477 0,07458947 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,04076477 0,07453018 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04076477 0,07447098 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,04076477 0,07441188 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,04076477 0,07435287 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04076477 0,07429395 ! lysogeny GO:0030069 18 11 0,000 0,04076477 0,07423513 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04076477 0,0741764 ! acrosome reaction GO:0007340 13 11 0,000 0,04076477 0,07411776 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04076477 0,07405922 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,04100592 0,07443853 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,04100592 0,07437982 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,04100592 0,07432121 ! cell cycle arrest GO:0007050 150 86 1,000 0,04188209 0,07584945 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,0427653 0,07738803 GO:0060538|skeletal muscle organ development, ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,04365549 0,07893682 ! carboxylic acid catabolic process GO:0046395 122 88 1,000 0,04365549 0,07887481 GO:0016054|organic acid catabolic process, ! lactation GO:0007595 20 12 0,000 0,04438846 0,08013615 ! reproductive cellular process GO:0048610 14 12 0,000 0,04438846 0,0800733 ! tRNA modification GO:0006400 14 12 0,000 0,04438846 0,08001055 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04438846 0,07994789 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04438846 0,07988534 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04438846 0,07982288 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04438846 0,07976052 ! non-recombinational repair GO:0000726 19 12 0,000 0,04438846 0,07969825 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04438846 0,07963608 ! peroxisomal transport GO:0043574 21 12 0,000 0,04438846 0,07957401 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04438846 0,07951204 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04438846 0,07945016 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04438846 0,07938838 ! palate development GO:0060021 15 12 0,000 0,04438846 0,0793267 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04438846 0,07926511 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04438846 0,07920361 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04438846 0,07914222 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04438846 0,07908091 ! arginine metabolic process GO:0006525 13 12 0,000 0,04438846 0,07901971 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04438846 0,07895859 ! methionine metabolic process GO:0006555 13 12 0,000 0,04438846 0,07889757 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04438846 0,07883665 ! Golgi organization GO:0007030 18 12 0,000 0,04438846 0,07877582 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04438846 0,07871508 ! monoamine transport GO:0015844 13 12 0,000 0,04438846 0,07865444 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04438846 0,07859389 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04438846 0,07853343 ! L-amino acid transport GO:0015807 20 12 0,000 0,04438846 0,07847307 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04438846 0,0784128 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04438846 0,07835262 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04438846 0,07829253 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04438846 0,07823254 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04438846 0,07817263 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04438846 0,07811282 ! cerebellum development GO:0021549 13 12 0,000 0,04438846 0,0780531 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04438846 0,07799348 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04438846 0,07793394 ! histone methylation GO:0016571 15 12 0,000 0,04438846 0,07787449 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04438846 0,07781514 ! gland morphogenesis GO:0022612 23 12 0,000 0,04438846 0,07775587 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04438846 0,0776967 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04438846 0,07763761 ! response to gamma radiation GO:0010332 20 12 0,000 0,04438846 0,07757862 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04438846 0,07751971 ! intestinal absorption GO:0050892 19 12 0,000 0,04438846 0,07746089 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04438846 0,07740217 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04438846 0,07734353 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04438846 0,07728498 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04438846 0,07722652 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04438846 0,07716815 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04438846 0,07710986 ! response to cold GO:0009409 14 12 0,000 0,04438846 0,07705167 ! reproductive developmental process GO:0003006 127 89 1,000 0,04455261 0,07727828 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,04728484 0,08195563 ! sulfur metabolic process GO:0006790 118 92 1,000 0,04728484 0,08189392 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04799867 0,08306768 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04799867 0,08300522 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04799867 0,08294286 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,04799867 0,08288059 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04799867 0,08281841 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04799867 0,08275633 ! lipid localization GO:0010876 24 13 0,000 0,04799867 0,08269434 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04799867 0,08263244 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04799867 0,08257064 ! organelle fusion GO:0048284 28 13 0,000 0,04799867 0,08250892 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04799867 0,0824473 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04799867 0,08238578 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04799867 0,08232434 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04799867 0,082263 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04799867 0,08220174 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04799867 0,08214058 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04799867 0,08207951 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04799867 0,08201853 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04799867 0,08195764 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04799867 0,08189684 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04799867 0,08183613 ! NAD metabolic process GO:0019674 21 13 0,000 0,04799867 0,08177551 ! exocrine system development GO:0035272 27 13 0,000 0,04799867 0,08171498 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04799867 0,08165454 ! bone mineralization GO:0030282 15 13 0,000 0,04799867 0,08159419 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04799867 0,08153393 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04799867 0,08147376 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04799867 0,08141367 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04799867 0,08135368 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04799867 0,08129377 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04799867 0,08123395 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,04799867 0,08117422 ! genitalia development GO:0048806 15 13 0,000 0,04799867 0,08111458 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04799867 0,08105502 ! cellular pigmentation GO:0033059 24 13 0,000 0,04799867 0,08099555 ! tissue regeneration GO:0042246 21 13 0,000 0,04799867 0,08093617 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04799867 0,08087688 ! cofactor transport GO:0051181 19 13 0,000 0,04799867 0,08081767 ! NADP metabolic process GO:0006739 18 13 0,000 0,04799867 0,08075855 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04799867 0,08069952 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04799867 0,08064057 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04799867 0,08058171 ! gas transport GO:0015669 18 13 0,000 0,04799867 0,08052293 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04799867 0,08046424 ! regulation of axon extension GO:0030516 23 13 0,000 0,04799867 0,08040564 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04799867 0,08034712 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04799867 0,08028868 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04799867 0,08023034 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04799867 0,08017207 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04799867 0,08011389 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04799867 0,0800558 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,048209 0,08034833 ! response to oxidative stress GO:0006979 141 94 1,000 0,04913977 0,08184031 ! regulation of binding GO:0051098 151 95 1,000 0,05007708 0,08334102 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,05102088 0,08485035 ! in utero embryonic development GO:0001701 147 96 1,000 0,05102088 0,08478904 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,05159545 0,08568197 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,05159545 0,08562015 ! superoxide anion generation GO:0042554 18 14 0,000 0,05159545 0,08555842 ! neuron maturation GO:0042551 21 14 0,000 0,05159545 0,08549678 ! regulation of S phase GO:0033261 18 14 0,000 0,05159545 0,08543522 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,05159545 0,08537376 ! myotube differentiation GO:0014902 21 14 0,000 0,05159545 0,08531238 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,05159545 0,0852511 ! inositol metabolic process GO:0006020 20 14 0,000 0,05159545 0,0851899 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,05159545 0,08512879 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,05159545 0,08506776 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,05159545 0,08500682 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,05159545 0,08494598 ! gene silencing by RNA GO:0031047 20 14 0,000 0,05159545 0,08488521 ! limbic system development GO:0021761 25 14 0,000 0,05159545 0,08482454 ! startle response GO:0001964 21 14 0,000 0,05159545 0,08476395 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,05159545 0,08470345 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,05159545 0,08464303 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,05159545 0,0845827 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,05159545 0,08452246 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,05159545 0,0844623 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,05159545 0,08440222 ! glycine metabolic process GO:0006544 22 14 0,000 0,05159545 0,08434224 ! pituitary gland development GO:0021983 23 14 0,000 0,05159545 0,08428233 ! cellular response to starvation GO:0009267 21 14 0,000 0,05159545 0,08422252 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,05159545 0,08416279 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,05159545 0,08410314 ! regulation of heart rate GO:0002027 23 14 0,000 0,05159545 0,08404357 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,05159545 0,0839841 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,05159545 0,0839247 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,05159545 0,08386539 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,05159545 0,08380616 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,05159545 0,08374702 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,05159545 0,08368796 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,05159545 0,08362898 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,05159545 0,08357009 ! axon cargo transport GO:0008088 27 14 0,000 0,05159545 0,08351128 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,05159545 0,08345255 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,05159545 0,08339391 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,05159545 0,08333534 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,05159545 0,08327686 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05159545 0,08321846 ! mRNA splice site selection GO:0006376 26 14 0,000 0,05159545 0,08316015 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,05159545 0,08310191 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,05159545 0,08304376 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,05159545 0,08298568 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,05159545 0,08292769 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,05159545 0,08286978 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,05159545 0,08281195 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,05159545 0,0827542 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,05159545 0,08269653 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,05159545 0,08263895 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,05159545 0,08258144 ! cell killing GO:0001906 20 14 0,000 0,05159545 0,08252401 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,05159545 0,08246666 ! cilium assembly GO:0042384 20 14 0,000 0,05159545 0,08240939 ! peptide hormone secretion GO:0030072 23 14 0,000 0,05159545 0,0823522 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,05485972 0,08750163 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05517884 0,08794964 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05517884 0,08788873 ! metencephalon development GO:0022037 19 15 0,000 0,05517884 0,08782791 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05517884 0,08776717 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05517884 0,08770652 ! skin development GO:0043588 25 15 0,000 0,05517884 0,08764595 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05517884 0,08758546 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05517884 0,08752506 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05517884 0,08746473 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05517884 0,0874045 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05517884 0,08734434 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05517884 0,08728427 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05517884 0,08722428 ! adult walking behavior GO:0007628 25 15 0,000 0,05517884 0,08716437 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05517884 0,08710455 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05517884 0,08704481 ! myoblast differentiation GO:0045445 27 15 0,000 0,05517884 0,08698515 ! centrosome cycle GO:0007098 16 15 0,000 0,05517884 0,08692557 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05517884 0,08686607 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05517884 0,08680666 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05517884 0,08674732 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05517884 0,08668807 ! cerebral cortex development GO:0021987 29 15 0,000 0,05517884 0,08662889 ! response to osmotic stress GO:0006970 22 15 0,000 0,05517884 0,0865698 ! vesicle coating GO:0006901 25 15 0,000 0,05517884 0,08651079 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05517884 0,08645186 ! DNA integration GO:0015074 22 15 0,000 0,05517884 0,08639301 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05517884 0,08633424 ! peptide secretion GO:0002790 27 15 0,000 0,05517884 0,08627555 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05517884 0,08621694 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05517884 0,0861584 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05517884 0,08609995 ! neuron recognition GO:0008038 22 15 0,000 0,05517884 0,08604158 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05517884 0,08598329 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05517884 0,08592507 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05517884 0,08586694 ! biomineral formation GO:0031214 18 15 0,000 0,05517884 0,08580888 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05517884 0,0857509 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05517884 0,085693 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05517884 0,08563518 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05517884 0,08557743 ! organic cation transport GO:0015695 19 15 0,000 0,05517884 0,08551976 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05517884 0,08546218 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05517884 0,08540466 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,05517884 0,08534723 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,05517884 0,08528987 ! defense response to virus GO:0051607 27 15 0,000 0,05517884 0,08523259 ! peptide hormone processing GO:0016486 19 15 0,000 0,05517884 0,08517539 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05517884 0,08511826 ! protein secretion GO:0009306 27 16 0,000 0,0587489 0,09056465 ! hormone secretion GO:0046879 25 16 0,000 0,0587489 0,09050399 ! bone remodeling GO:0046849 24 16 0,000 0,0587489 0,09044342 ! endothelial cell migration GO:0043542 22 16 0,000 0,0587489 0,09038292 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,0587489 0,0903225 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,0587489 0,09026217 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,0587489 0,09020191 ! glial cell development GO:0021782 24 16 0,000 0,0587489 0,09014174 ! patterning of blood vessels GO:0001569 24 16 0,000 0,0587489 0,09008164 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,0587489 0,09002163 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,0587489 0,08996169 ! protein polyubiquitination GO:0000209 26 16 0,000 0,0587489 0,08990184 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,0587489 0,08984206 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,0587489 0,08978237 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,0587489 0,08972275 ! fructose metabolic process GO:0006000 20 16 0,000 0,0587489 0,08966321 ! regulation of protein binding GO:0043393 27 16 0,000 0,0587489 0,08960375 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,0587489 0,08954438 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,0587489 0,08948507 ! protein export from nucleus GO:0006611 24 16 0,000 0,0587489 0,08942585 ! negative regulation of immune response GO:0050777 28 16 0,000 0,0587489 0,08936671 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,0587489 0,08930764 ! DNA replication initiation GO:0006270 25 16 0,000 0,0587489 0,08924865 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,0587489 0,08918974 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,0587489 0,08913091 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,0587489 0,08907216 ! diencephalon development GO:0021536 25 16 0,000 0,0587489 0,08901348 ! oogenesis GO:0048477 23 16 0,000 0,0587489 0,08895488 ! G1 phase GO:0051318 27 16 0,000 0,0587489 0,08889636 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,0587489 0,08883791 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,0587489 0,08877954 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,0587489 0,08872125 ! steroid catabolic process GO:0006706 22 16 0,000 0,0587489 0,08866303 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,0587489 0,08860489 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,0587489 0,08854683 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,0587489 0,08848884 ! sperm-egg recognition GO:0035036 16 16 0,000 0,0587489 0,08843093 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,0587489 0,0883731 ! nerve development GO:0021675 18 16 0,000 0,0587489 0,08831533 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,0587489 0,08825765 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,0587489 0,08820004 ! negative regulation of translation GO:0017148 22 16 0,000 0,0587489 0,08814251 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,06230567 0,09341789 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,06230567 0,09335703 ! negative regulation of defense response GO:0031348 19 17 0,000 0,06230567 0,09329625 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,06230567 0,09323555 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,06230567 0,09317493 ! glycerol metabolic process GO:0006071 20 17 0,000 0,06230567 0,09311438 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,06230567 0,09305392 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,06230567 0,09299353 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,06230567 0,09293323 ! signal complex assembly GO:0007172 29 17 0,000 0,06230567 0,092873 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,06230567 0,09281285 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,06230567 0,09275277 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,06230567 0,09269278 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,06230567 0,09263286 ! memory GO:0007613 25 17 0,000 0,06230567 0,09257302 ! keratinization GO:0031424 17 17 0,000 0,06230567 0,09251326 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,06230567 0,09245357 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,06230567 0,09239396 ! retinoid metabolic process GO:0001523 22 17 0,000 0,06230567 0,09233443 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,06230567 0,09227498 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,06230567 0,0922156 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,06230567 0,09215629 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,06230567 0,09209707 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,06230567 0,09203792 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,06230567 0,09197884 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,06230567 0,09191984 ! membrane budding GO:0006900 29 17 0,000 0,06230567 0,09186092 ! heme metabolic process GO:0042168 27 17 0,000 0,06230567 0,09180207 ! neuromuscular junction development GO:0007528 23 17 0,000 0,06230567 0,0917433 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,06230567 0,0916846 ! body fluid secretion GO:0007589 27 17 0,000 0,06230567 0,09162598 ! stem cell differentiation GO:0048863 36 17 0,000 0,06230567 0,09156744 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,06230567 0,09150896 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,06230567 0,09145057 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,06230567 0,09139224 ! sensory perception of pain GO:0019233 23 17 0,000 0,06230567 0,09133399 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,06230567 0,09127582 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,06230567 0,09121772 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,06230567 0,09115969 ! synaptogenesis GO:0007416 24 17 0,000 0,06230567 0,09110174 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,06230567 0,09104386 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,06230567 0,09098606 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,06230567 0,09092832 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,06230567 0,09087066 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,06230567 0,09081308 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,06230567 0,09075557 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,06230567 0,09069812 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,06230567 0,09064076 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,0658492 0,09573525 ! positive regulation of translation GO:0045727 28 18 0,000 0,0658492 0,09567477 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,0658492 0,09561437 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,0658492 0,09555405 ! cAMP metabolic process GO:0046058 33 18 0,000 0,0658492 0,0954938 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,0658492 0,09543363 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,0658492 0,09537353 ! axis specification GO:0009798 26 18 0,000 0,0658492 0,09531351 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,0658492 0,09525356 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,0658492 0,09519369 ! pancreas development GO:0031016 26 18 0,000 0,0658492 0,0951339 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,0658492 0,09507418 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,0658492 0,09501453 ! glutamine metabolic process GO:0006541 23 18 0,000 0,0658492 0,09495496 ! pigmentation during development GO:0048066 31 18 0,000 0,0658492 0,09489547 ! central nervous system neuron development GO:0021954 30 18 0,000 0,0658492 0,09483605 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,0658492 0,0947767 ! fucose metabolic process GO:0006004 26 18 0,000 0,0658492 0,09471743 ! response to fungus GO:0009620 19 18 0,000 0,0658492 0,09465823 ! peptide cross-linking GO:0018149 31 18 0,000 0,0658492 0,0945991 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,0658492 0,09454005 ! heart process GO:0003015 27 18 0,000 0,0658492 0,09448108 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,0658492 0,09442217 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,0658492 0,09436334 ! visual learning GO:0008542 35 18 0,000 0,0658492 0,09430459 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,0658492 0,0942459 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,0658492 0,09418729 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,0658492 0,09412875 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,0658492 0,09407029 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,0658492 0,0940119 ! vitamin transport GO:0051180 24 18 0,000 0,0658492 0,09395358 ! hormone transport GO:0009914 27 18 0,000 0,0658492 0,09389533 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,0658492 0,09383715 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,0658492 0,09377905 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,0658492 0,09372102 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,0658492 0,09366306 ! cell-cell recognition GO:0009988 20 18 0,000 0,0658492 0,09360517 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,0658492 0,09354735 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,0658492 0,09348961 ! regulation of glucose import GO:0046324 21 18 0,000 0,0658492 0,09343193 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,0658492 0,09337433 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,0658492 0,0933168 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,0658492 0,09325934 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06937955 0,09819874 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,06937955 0,09813835 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06937955 0,09807803 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06937955 0,09801779 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,06937955 0,09795762 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06937955 0,09789752 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,06937955 0,0978375 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06937955 0,09777755 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06937955 0,09771767 ! regeneration GO:0031099 32 19 0,000 0,06937955 0,09765787 ! response to alkaloid GO:0043279 32 19 0,000 0,06937955 0,09759814 ! sensory perception of taste GO:0050909 23 19 0,000 0,06937955 0,09753848 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,06937955 0,0974789 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06937955 0,09741939 ! peroxisome organization GO:0007031 29 19 0,000 0,06937955 0,09735995 ! digestive system process GO:0022600 30 19 0,000 0,06937955 0,09730059 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06937955 0,09724129 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06937955 0,09718207 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06937955 0,09712292 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06937955 0,09706384 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,06937955 0,09700484 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,06937955 0,09694591 ! response to starvation GO:0042594 30 19 0,000 0,06937955 0,09688704 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,06937955 0,09682825 ! cytolysis GO:0019835 20 19 0,000 0,06937955 0,09676953 ! renal system process GO:0003014 35 19 0,000 0,06937955 0,09671089 ! vasodilation GO:0042311 33 19 0,000 0,06937955 0,09665231 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06937955 0,0965938 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,06937955 0,09653537 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06937955 0,096477 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,06937955 0,09641871 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,06937955 0,09636048 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06937955 0,09630233 ! sarcomere organization GO:0045214 23 19 0,000 0,06937955 0,09624425 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06937955 0,09618623 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06937955 0,09612829 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06937955 0,09607042 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,06937955 0,09601261 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,06937955 0,09595488 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,06937955 0,09589721 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,06937955 0,09583962 ! protein stabilization GO:0050821 26 19 0,000 0,06937955 0,09578209 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,07289675 0,1005774 ! iron ion transport GO:0006826 37 20 0,000 0,07289675 0,10051711 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,07289675 0,10045688 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,07289675 0,10039673 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,07289675 0,10033664 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,07289675 0,10027663 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,07289675 0,1002167 ! spinal cord development GO:0021510 31 20 0,000 0,07289675 0,10015683 ! response to ethanol GO:0045471 37 20 0,000 0,07289675 0,10009703 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,07289675 0,10003731 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,07289675 0,09997766 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,07289675 0,09991808 ! chromosome condensation GO:0030261 31 20 0,000 0,07289675 0,09985857 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,07289675 0,09979913 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,07289675 0,09973976 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,07289675 0,09968046 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,07289675 0,09962123 ! pallium development GO:0021543 38 20 0,000 0,07289675 0,09956207 ! DNA modification GO:0006304 28 20 0,000 0,07289675 0,09950299 ! collagen fibril organization GO:0030199 45 20 0,000 0,07289675 0,09944397 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,07289675 0,09938502 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,07289675 0,09932614 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,07289675 0,09926734 ! collagen catabolic process GO:0030574 25 20 0,000 0,07289675 0,0992086 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,07289675 0,09914993 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,07289675 0,09909133 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,07289675 0,0990328 ! alditol metabolic process GO:0019400 24 20 0,000 0,07289675 0,09897434 ! actin filament-based movement GO:0030048 34 20 0,000 0,07289675 0,09891595 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07640087 0,10360966 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07640087 0,10354861 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07640087 0,10348763 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07640087 0,10342672 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07640087 0,10336588 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07640087 0,10330511 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07640087 0,10324441 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07640087 0,10318379 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07640087 0,10312323 ! vesicle docking GO:0048278 27 21 0,000 0,07640087 0,10306275 ! phototransduction GO:0007602 25 21 0,000 0,07640087 0,10300234 ! dendrite development GO:0016358 35 21 0,000 0,07640087 0,102942 ! visual behavior GO:0007632 39 21 0,000 0,07640087 0,10288173 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07640087 0,10282153 ! ovarian follicle development GO:0001541 30 21 0,000 0,07640087 0,1027614 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,07640087 0,10270134 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07640087 0,10264135 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07640087 0,10258143 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07640087 0,10252158 ! cell aging GO:0007569 32 21 0,000 0,07640087 0,1024618 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,07640087 0,10240209 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,07640087 0,10234245 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07640087 0,10228288 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07640087 0,10222338 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07640087 0,10216395 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07640087 0,10210459 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07640087 0,10204529 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07640087 0,10198607 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07640087 0,10192691 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07640087 0,10186782 ! fatty acid transport GO:0015908 30 21 0,000 0,07640087 0,1018088 ! immunoglobulin production GO:0002377 33 21 0,000 0,07640087 0,10174985 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07640087 0,10169097 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,07640087 0,10163215 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07640087 0,10157341 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07640087 0,10151473 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07640087 0,10145611 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07640087 0,10139757 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07640087 0,1013391 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07640087 0,10128069 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07640087 0,10122234 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07640087 0,10116407 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07640087 0,10110586 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07640087 0,10104772 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,07989193 0,10560428 ! viral genome replication GO:0019079 29 22 0,000 0,07989193 0,10554362 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07989193 0,10548304 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07989193 0,10542252 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07989193 0,10536207 ! molting cycle process GO:0022404 40 22 0,000 0,07989193 0,10530169 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07989193 0,10524138 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07989193 0,10518114 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,07989193 0,10512097 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,07989193 0,10506086 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,07989193 0,10500083 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,07989193 0,10494086 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,07989193 0,10488096 ! lysosome organization GO:0007040 37 22 0,000 0,07989193 0,10482113 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07989193 0,10476137 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,07989193 0,10470168 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07989193 0,10464205 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,07989193 0,1045825 ! membrane depolarization GO:0051899 35 22 0,000 0,07989193 0,10452301 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,07989193 0,10446359 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07989193 0,10440423 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,07989193 0,10434494 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07989193 0,10428573 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07989193 0,10422657 ! blastocyst development GO:0001824 37 22 0,000 0,07989193 0,10416749 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,07989193 0,10410847 ! neuron fate commitment GO:0048663 32 23 0,000 0,08337001 0,10857928 ! embryonic pattern specification GO:0009880 31 23 0,000 0,08337001 0,10851783 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,08337001 0,10845646 ! myelination GO:0042552 35 23 0,000 0,08337001 0,10839515 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,08337001 0,10833391 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,08337001 0,10827273 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,08337001 0,10821163 ! vesicle targeting GO:0006903 32 23 0,000 0,08337001 0,1081506 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,08337001 0,10808964 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,08337001 0,10802874 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,08337001 0,10796791 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,08337001 0,10790715 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,08337001 0,10784646 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,08337001 0,10778584 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,08337001 0,10772529 ! cell fate determination GO:0001709 45 23 0,000 0,08337001 0,1076648 ! pentose metabolic process GO:0019321 31 23 0,000 0,08337001 0,10760438 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,08337001 0,10754403 ! spermatid development GO:0007286 33 23 0,000 0,08337001 0,10748375 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,08337001 0,10742354 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,08337001 0,10736339 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,08337001 0,10730331 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,08337001 0,1072433 ! telomere organization GO:0032200 32 23 0,000 0,08337001 0,10718335 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,08337001 0,10712347 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,08337001 0,10706366 ! regulation of amine transport GO:0051952 38 23 0,000 0,08337001 0,10700391 ! liver development GO:0001889 40 23 0,000 0,08337001 0,10694423 ! initiation of viral infection GO:0019059 42 24 0,000 0,08683513 0,11132709 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08683513 0,11126507 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08683513 0,11120312 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08683513 0,11114123 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,08683513 0,11107942 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08683513 0,11101767 ! sperm motility GO:0030317 27 24 0,000 0,08683513 0,110956 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,08683513 0,11089439 ! vacuole organization GO:0007033 39 24 0,000 0,08683513 0,11083285 ! receptor metabolic process GO:0043112 37 24 0,000 0,08683513 0,11077138 ! response to toxin GO:0009636 38 24 0,000 0,08683513 0,11070998 ! negative regulation of cell development GO:0010721 56 24 0,000 0,08683513 0,11064864 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08683513 0,11058737 ! base-excision repair GO:0006284 31 24 0,000 0,08683513 0,11052617 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08683513 0,11046504 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,08683513 0,11040398 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,08683513 0,11034298 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08683513 0,11028205 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08683513 0,11022119 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,09028735 0,11453994 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,09028735 0,11447679 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,09028735 0,11441372 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,09028735 0,11435072 GO:0006479|protein amino acid methylation, ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,09028735 0,11428778 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,09028735 0,11422492 ! peptide transport GO:0015833 43 25 0,000 0,09028735 0,11416212 ! male gonad development GO:0008584 33 25 0,000 0,09028735 0,1140994 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,09028735 0,11403674 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,09028735 0,11397415 ! phospholipid transport GO:0015914 35 25 0,000 0,09028735 0,11391163 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,09028735 0,11384918 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,09028735 0,1137868 ! detection of light stimulus GO:0009583 30 25 0,000 0,09028735 0,11372448 ! leukocyte proliferation GO:0070661 39 25 0,000 0,09028735 0,11366224 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,09028735 0,11360006 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,09372672 0,11786301 ! translational initiation GO:0006413 43 26 0,000 0,09372672 0,11779861 ! regulation of pH GO:0006885 36 26 0,000 0,09372672 0,11773427 ! circadian rhythm GO:0007623 42 26 0,000 0,09372672 0,11767001 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,09372672 0,11760581 ! post-embryonic development GO:0009791 42 26 0,000 0,09372672 0,11754168 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,09372672 0,11747763 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,09372672 0,11741364 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,09372672 0,11734973 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,09372672 0,11728588 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,09372672 0,1172221 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,09372672 0,1171584 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,09372672 0,11709476 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,09372672 0,11703119 ! regulation of coagulation GO:0050818 39 26 0,000 0,09372672 0,11696769 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09715328 0,12117817 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09715328 0,12111249 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09715328 0,12104688 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09715328 0,12098134 ! membrane docking GO:0022406 39 27 0,000 0,09715328 0,12091588 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09715328 0,12085048 ! catechol metabolic process GO:0009712 43 27 0,000 0,09715328 0,12078516 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09715328 0,1207199 ! acute-phase response GO:0006953 42 27 0,000 0,09715328 0,12065472 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09715328 0,12058961 ! myofibril assembly GO:0030239 36 27 0,000 0,09715328 0,12052456 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09715328 0,12045959 ! response to ionizing radiation GO:0010212 47 27 0,000 0,09715328 0,12039469 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09715328 0,12032985 ! natural killer cell activation GO:0030101 35 27 0,000 0,09715328 0,12026509 ! lipid oxidation GO:0034440 38 27 0,000 0,09715328 0,1202004 GO:0019395|fatty acid oxidation, ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,09715328 0,12013577 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09715328 0,12007122 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,09715328 0,12000673 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,09715328 0,11994232 ! gene silencing GO:0016458 41 27 0,000 0,09715328 0,11987797 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,10056708 0,12402374 ! phenol metabolic process GO:0018958 44 28 0,000 0,10056708 0,12395728 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,10056708 0,12389088 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,10056708 0,12382456 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,10056708 0,12375831 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,10056708 0,12369213 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,10056708 0,12362602 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,10056708 0,12355998 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,10056708 0,12349401 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,10056708 0,12342811 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,10056708 0,12336228 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,10056708 0,12329652 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,10056708 0,12323084 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,10056708 0,12316522 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,10056708 0,12309967 ! mesoderm formation GO:0001707 46 28 0,000 0,10056708 0,12303419 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,10056708 0,12296878 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,10056708 0,12290344 ! ensheathment of neurons GO:0007272 43 28 0,000 0,10056708 0,12283817 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,10056708 0,12277297 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,10056708 0,12270784 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,10056708 0,12264278 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,10396816 0,12672325 ! regulation of innate immune response GO:0045088 38 29 0,000 0,10396816 0,12665613 ! ovulation cycle process GO:0022602 41 29 0,000 0,10396816 0,12658908 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,10396816 0,12652211 ! protein targeting to membrane GO:0006612 53 29 0,000 0,10396816 0,1264552 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,10396816 0,12638836 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,10396816 0,12632159 ! muscle cell development GO:0055001 38 29 0,000 0,10396816 0,1262549 ! formation of primary germ layer GO:0001704 48 29 0,000 0,10396816 0,12618827 ! telencephalon development GO:0021537 52 29 0,000 0,10396816 0,12612172 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,10396816 0,12605523 ! eye morphogenesis GO:0048592 51 29 0,000 0,10396816 0,12598882 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,10396816 0,12592247 ! tissue homeostasis GO:0001894 42 29 0,000 0,10396816 0,1258562 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,10735659 0,12988961 ! organic anion transport GO:0015711 51 30 0,000 0,10735659 0,12982132 ! cholesterol transport GO:0030301 46 30 0,000 0,10735659 0,1297531 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,10735659 0,12968495 ! spliceosome assembly GO:0000245 49 30 0,000 0,10735659 0,12961687 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,10735659 0,12954887 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,10735659 0,12948094 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,10735659 0,12941307 ! ceramide metabolic process GO:0006672 43 30 0,000 0,10735659 0,12934528 ! ovulation cycle GO:0042698 43 30 0,000 0,10735659 0,12927756 ! hindbrain development GO:0030902 45 30 0,000 0,10735659 0,12920991 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,10735659 0,12914234 ! adult locomotory behavior GO:0008344 47 30 0,000 0,10735659 0,12907483 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,10735659 0,12900739 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,10735659 0,12894002 ! response to heat GO:0009408 41 30 0,000 0,10735659 0,12887273 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,10735659 0,1288055 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,10735659 0,12873835 ! negative regulation of secretion GO:0051048 49 31 0,000 0,11073239 0,13271729 ! mammary gland development GO:0030879 57 31 0,000 0,11073239 0,13264817 ! glial cell differentiation GO:0010001 55 31 0,000 0,11073239 0,13257912 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,11073239 0,13251014 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,11073239 0,13244123 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,11073239 0,13237239 ! odontogenesis GO:0042476 50 31 0,000 0,11073239 0,13230363 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,11073239 0,13223494 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,11073239 0,13216631 ! metanephros development GO:0001656 58 31 0,000 0,11073239 0,13209776 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,11073239 0,13202928 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,11073239 0,13196087 ! cell fate specification GO:0001708 37 31 0,000 0,11073239 0,13189254 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,11073239 0,13182427 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,11073239 0,13175607 ! RNA modification GO:0009451 40 31 0,000 0,11073239 0,13168795 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,11409561 0,13561752 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,11409561 0,13554747 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,11409561 0,13547749 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,11409561 0,13540759 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,11409561 0,13533775 ! peripheral nervous system development GO:0007422 53 32 0,000 0,11409561 0,13526799 ! regulation of protein stability GO:0031647 48 32 0,000 0,11409561 0,1351983 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,11409561 0,13512869 ! cytokine production GO:0001816 44 32 0,000 0,11409561 0,13505914 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,11409561 0,13498966 ! vesicle localization GO:0051648 47 32 0,000 0,11409561 0,13492026 ! RNA export from nucleus GO:0006405 44 33 0,000 0,11744631 0,13881116 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11744631 0,13873986 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11744631 0,13866864 ! ear morphogenesis GO:0042471 42 33 0,000 0,11744631 0,13859749 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11744631 0,13852642 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,11744631 0,13845541 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11744631 0,13838448 ! nucleus organization GO:0006997 49 33 0,000 0,11744631 0,13831363 ! female gonad development GO:0008585 49 33 0,000 0,11744631 0,13824284 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,11744631 0,13817213 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11744631 0,13810149 ! lipid homeostasis GO:0055088 55 33 0,000 0,11744631 0,13803092 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11744631 0,13796043 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11744631 0,13789 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,11744631 0,13781965 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11744631 0,13774937 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,11744631 0,13767916 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,11744631 0,13760902 ! mRNA catabolic process GO:0006402 48 34 0,000 0,12078453 0,14144827 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,12078453 0,14137629 ! feeding behavior GO:0007631 45 34 0,000 0,12078453 0,14130438 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,12078453 0,14123254 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,12078453 0,14116078 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,12078453 0,14108909 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,12078453 0,14101747 ! female gamete generation GO:0007292 43 34 0,000 0,12078453 0,14094592 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,12078453 0,14087445 ! polyol metabolic process GO:0019751 44 34 0,000 0,12078453 0,14080305 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,12078453 0,14073172 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,12078453 0,14066046 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,12411031 0,14446038 ! Notch signaling pathway GO:0007219 56 35 0,000 0,12411031 0,14438731 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,12411031 0,14431431 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,12411031 0,14424139 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,12411031 0,14416854 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,12411031 0,14409576 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,12411031 0,14402306 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,12411031 0,14395043 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,12411031 0,14387788 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,12411031 0,14380539 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,12411031 0,14373298 ! glycogen metabolic process GO:0005977 48 35 0,000 0,12411031 0,14366065 ! pigment metabolic process GO:0042440 61 35 0,000 0,12411031 0,14358838 ! protein homooligomerization GO:0051260 52 35 0,000 0,12411031 0,14351619 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,1274237 0,14727362 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,1274237 0,14719965 ! negative regulation of binding GO:0051100 58 36 0,000 0,1274237 0,14712576 ! organic ether metabolic process GO:0018904 46 36 0,000 0,1274237 0,14705193 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,1274237 0,14697819 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,1274237 0,14690451 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,1274237 0,14683091 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,1274237 0,14675739 ! glucan metabolic process GO:0044042 49 36 0,000 0,1274237 0,14668394 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,13072474 0,15040866 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,13072474 0,15033345 ! learning GO:0007612 67 37 0,000 0,13072474 0,15025833 ! ion transmembrane transport GO:0034220 56 37 0,000 0,13072474 0,15018327 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,13072474 0,15010829 ! regulation of protein secretion GO:0050708 51 37 0,000 0,13072474 0,15003339 ! amino acid activation GO:0043038 52 37 0,000 0,13072474 0,14995856 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,13072474 0,1498838 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,13401349 0,15357799 ! gliogenesis GO:0042063 71 38 0,000 0,13401349 0,15350151 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,13401349 0,1534251 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,13401349 0,15334877 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,13401349 0,15327251 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,13401349 0,15319633 ! phagocytosis GO:0006909 60 38 0,000 0,13401349 0,15312023 ! pigmentation GO:0043473 74 38 0,000 0,13401349 0,1530442 ! maintenance of location in cell GO:0051651 69 38 0,000 0,13401349 0,15296825 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,13728998 0,15663043 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,13728998 0,15655278 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,13728998 0,1564752 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,13728998 0,1563977 ! male sex differentiation GO:0046661 53 39 0,000 0,13728998 0,15632027 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,13728998 0,15624293 ! chromatin remodeling GO:0006338 68 39 0,000 0,13728998 0,15616565 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,13728998 0,15608846 ! JNK cascade GO:0007254 54 39 0,000 0,13728998 0,15601134 ! developmental growth GO:0048589 62 39 0,000 0,13728998 0,1559343 ! cell growth GO:0016049 61 39 0,000 0,13728998 0,15585733 ! synapse organization GO:0050808 55 39 0,000 0,13728998 0,15578044 ! response to calcium ion GO:0051592 58 40 0,000 0,14055426 0,15940572 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,14055426 0,15932716 ! regulation of tube size GO:0035150 60 40 0,000 0,14055426 0,15924867 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,14055426 0,15917026 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,14055426 0,15909193 ! peptide metabolic process GO:0006518 56 40 0,000 0,14055426 0,15901367 ! inner ear development GO:0048839 57 40 0,000 0,14055426 0,1589355 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,14055426 0,1588574 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,14055426 0,15877937 ! double-strand break repair GO:0006302 67 40 0,000 0,14055426 0,15870142 ! B cell differentiation GO:0030183 62 40 0,000 0,14055426 0,15862355 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,14055426 0,15854576 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,14055426 0,15846804 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,14380638 0,1620552 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,14380638 0,16197584 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,14380638 0,16189656 ! endosome transport GO:0016197 71 41 0,000 0,14380638 0,16181735 ! striated muscle contraction GO:0006941 62 41 0,000 0,14380638 0,16173822 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,14380638 0,16165917 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,14380638 0,1615802 ! biopolymer methylation GO:0043414 62 41 0,000 0,14380638 0,1615013 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,14380638 0,16142248 ! mitochondrial transport GO:0006839 60 42 0,000 0,14704637 0,16497886 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,14704637 0,16489842 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,14704637 0,16481806 ! cellular component disassembly GO:0022411 64 42 0,000 0,14704637 0,16473778 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,14704637 0,16465758 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,14704637 0,16457745 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,14704637 0,1644974 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,14704637 0,16441743 ! excretion GO:0007588 63 42 0,000 0,14704637 0,16433754 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,14704637 0,16425773 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,14704637 0,16417799 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,14704637 0,16409833 ! leukocyte migration GO:0050900 60 43 0,000 0,1502743 0,16761924 ! neuromuscular process GO:0050905 79 43 0,000 0,1502743 0,16753799 ! activation of caspase activity GO:0006919 65 43 0,000 0,1502743 0,16745682 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,1502743 0,16737573 ! tRNA processing GO:0008033 49 43 0,000 0,1502743 0,16729471 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,1502743 0,16721378 ! vesicle organization GO:0016050 79 43 0,000 0,1502743 0,16713292 ! methylation GO:0032259 64 43 0,000 0,1502743 0,16705214 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,15349018 0,17054465 ! regulation of action potential GO:0001508 71 44 0,000 0,15349018 0,1704623 ! regulation of ion transport GO:0043269 57 44 0,000 0,15349018 0,17038003 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,15349018 0,17029784 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,15349018 0,17021573 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,15349018 0,1701337 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,15349018 0,17005175 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,15349018 0,16996987 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,15349018 0,16988808 ! RNA catabolic process GO:0006401 64 45 0,000 0,15669409 0,17335084 ! positive regulation of defense response GO:0031349 59 45 0,000 0,15669409 0,1732675 ! regulation of translational initiation GO:0006446 64 45 0,000 0,15669409 0,17318424 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,15669409 0,17310106 ! cell recognition GO:0008037 58 45 0,000 0,15669409 0,17301795 ! cell maturation GO:0048469 60 45 0,000 0,15669409 0,17293493 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,15988605 0,1763731 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,15988605 0,17628855 ! cell redox homeostasis GO:0045454 63 46 0,000 0,15988605 0,17620408 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,15988605 0,17611969 ! regulation of ossification GO:0030278 71 46 0,000 0,15988605 0,17603538 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,15988605 0,17595115 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,16306611 0,17936492 ! viral infectious cycle GO:0019058 71 47 0,000 0,16306611 0,17927918 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,16306611 0,17919352 ! endocrine system development GO:0035270 83 47 0,000 0,16306611 0,17910795 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,16306611 0,17902245 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,16306611 0,17893704 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,16306611 0,17885171 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,16306611 0,17876646 ! chloride transport GO:0006821 67 48 0,000 0,16623431 0,18215289 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,16623431 0,18206615 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,16623431 0,18197949 ! response to temperature stimulus GO:0009266 62 48 0,000 0,16623431 0,18189292 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,16623431 0,18180643 ! gastrulation GO:0007369 73 48 0,000 0,16623431 0,18172002 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,16623431 0,18163369 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,16623431 0,18154744 ! regulation of endocytosis GO:0030100 63 48 0,000 0,16623431 0,18146128 ! nuclear export GO:0051168 69 48 0,000 0,16623431 0,1813752 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,16623431 0,1812892 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,1693907 0,18464389 ! sensory perception of smell GO:0007608 61 49 0,000 0,1693907 0,18455643 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,1693907 0,18446904 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,1693907 0,18438174 ! RNA elongation GO:0006354 62 49 0,000 0,1693907 0,18429452 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,1693907 0,18420738 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,1693907 0,18412033 ! germ cell development GO:0007281 68 49 0,000 0,1693907 0,18403336 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,1693907 0,18394647 ! maintenance of location GO:0051235 84 49 0,000 0,1693907 0,18385966 ! ear development GO:0043583 72 50 0,000 0,17253532 0,18718455 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,17253532 0,1870963 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,17253532 0,18700813 ! proton transport GO:0015992 75 50 0,000 0,17253532 0,18692004 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,17253532 0,18683204 ! positive regulation of secretion GO:0051047 71 51 0,000 0,17566822 0,19013502 ! hydrogen transport GO:0006818 77 51 0,000 0,17566822 0,19004558 ! muscle fiber development GO:0048747 74 51 0,000 0,17566822 0,18995623 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,17566822 0,18986697 ! adult behavior GO:0030534 80 51 0,000 0,17566822 0,18977779 ! transition metal ion transport GO:0000041 74 52 0,000 0,17878944 0,19305902 ! aging GO:0007568 79 52 0,000 0,17878944 0,19296842 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,17878944 0,19287791 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,17878944 0,19278748 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,18189901 0,19604861 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,18189901 0,19595678 ! kidney development GO:0001822 90 53 0,000 0,18189901 0,19586504 ! single fertilization GO:0007338 59 53 0,000 0,18189901 0,19577339 ! amino acid transport GO:0006865 84 54 0,000 0,18499699 0,19901454 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,18499699 0,1989215 ! DNA catabolic process GO:0006308 67 54 0,000 0,18499699 0,19882854 ! detection of external stimulus GO:0009581 66 54 0,000 0,18499699 0,19873567 ! exocytosis GO:0006887 74 55 0,000 0,18808341 0,20195698 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,18808341 0,20186274 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,18808341 0,20176859 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,19115833 0,20497163 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,19422177 0,2081594 GO:0048609|reproductive process in a multicellular organism, ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,19422177 0,20806245 ! camera-type eye development GO:0043010 88 57 0,000 0,19422177 0,20796558 ! secondary metabolic process GO:0019748 84 57 0,000 0,19422177 0,20786881 ! developmental maturation GO:0021700 75 57 0,000 0,19422177 0,20777213 ! gonad development GO:0008406 79 57 0,000 0,19422177 0,20767553 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,19727378 0,21084094 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,19727378 0,21074301 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,19727378 0,21064517 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,20031441 0,21379265 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,20031441 0,21369348 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,2033437 0,21682453 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,2033437 0,21672405 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,2033437 0,21662367 ! regulation of heart contraction GO:0008016 91 60 0,000 0,2033437 0,21652338 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,2033437 0,21642319 ! fertilization GO:0009566 68 60 0,000 0,2033437 0,21632309 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,20636168 0,21943221 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,20636168 0,21933081 ! urogenital system development GO:0001655 101 61 0,000 0,20636168 0,2192295 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,20636168 0,21912829 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,20636168 0,21902717 ! extracellular matrix organization GO:0030198 103 61 0,000 0,20636168 0,21892614 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,20636168 0,21882521 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,20636168 0,21872437 ! neurotransmitter transport GO:0006836 81 62 0,000 0,20936841 0,221809 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,20936841 0,22170688 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,20936841 0,22160485 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,20936841 0,22150292 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,21236391 0,22456873 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,21236391 0,22446553 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,21534824 0,22751536 ! reproductive structure development GO:0048608 90 65 0,000 0,21832143 0,23055064 ! regulation of caspase activity GO:0043281 97 65 0,000 0,21832143 0,23044483 ! B cell activation GO:0042113 104 65 0,000 0,21832143 0,23033912 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,21832143 0,23023351 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,21832143 0,23012799 ! defense response to bacterium GO:0042742 73 65 0,000 0,21832143 0,23002258 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,21832143 0,22991725 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,21832143 0,22981203 ! activation of immune response GO:0002253 83 65 0,000 0,21832143 0,2297069 ! antigen processing and presentation GO:0019882 96 66 0,000 0,22128352 0,23271701 ! axon guidance GO:0007411 99 66 0,000 0,22128352 0,23261065 ! regulation of immune effector process GO:0002697 101 66 0,000 0,22128352 0,23250439 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,22423456 0,23549748 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,22423456 0,23539 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,22423456 0,23528261 ! acute inflammatory response GO:0002526 92 68 0,000 0,22717458 0,2382588 ! learning or memory GO:0007611 123 68 0,000 0,22717458 0,2381502 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,22717458 0,23804171 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,22717458 0,23793331 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,22717458 0,23782501 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,22717458 0,23771681 ! rhythmic process GO:0048511 105 68 0,000 0,22717458 0,23760871 ! inorganic anion transport GO:0015698 93 68 0,000 0,22717458 0,2375007 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,23010363 0,24045359 ! response to drug GO:0042493 108 69 0,000 0,23010363 0,2403444 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,23010363 0,2402353 ! response to metal ion GO:0010038 103 70 0,000 0,23302175 0,24317152 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,23302175 0,24306124 ! humoral immune response GO:0006959 86 70 0,000 0,23302175 0,24295105 ! eye development GO:0001654 111 70 0,000 0,23302175 0,24284097 ! amine transport GO:0015837 101 70 0,000 0,23302175 0,24273099 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,23302175 0,24262111 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,23592897 0,24553694 ! muscle cell differentiation GO:0042692 104 71 0,000 0,23592897 0,24542589 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,23592897 0,24531494 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,23592897 0,24520408 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,23592897 0,24509333 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,23592897 0,24498268 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,23882534 0,24787829 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,23882534 0,24776648 ! negative regulation of transport GO:0051051 116 73 0,000 0,2417109 0,25064701 ! regulation of blood pressure GO:0008217 107 73 0,000 0,2417109 0,25053405 ! mitochondrion organization GO:0007005 104 73 0,000 0,2417109 0,2504212 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,2417109 0,25030845 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,24458568 0,2531715 ! digestion GO:0007586 97 74 0,000 0,24458568 0,25305761 ! protein import into nucleus GO:0006606 118 74 0,000 0,24458568 0,25294382 ! blood coagulation GO:0007596 116 75 0,000 0,24744973 0,25579073 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,24744973 0,25567582 ! regulation of ligase activity GO:0051340 114 75 0,000 0,24744973 0,25556101 ! nuclear import GO:0051170 121 75 0,000 0,24744973 0,25544631 ! amine biosynthetic process GO:0009309 97 76 0,000 0,25030308 0,25827595 ! tRNA metabolic process GO:0006399 95 76 0,000 0,25030308 0,25816013 ! response to unfolded protein GO:0006986 99 76 0,000 0,25030308 0,25804441 ! regulation of protein transport GO:0051223 114 76 0,000 0,25030308 0,2579288 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 0,000 0,25314578 0,26074129 ! gland development GO:0048732 148 77 0,000 0,25314578 0,26062457 ! sex differentiation GO:0007548 105 77 0,000 0,25314578 0,26050796 ! protein ubiquitination GO:0016567 125 77 0,000 0,25314578 0,26039145 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,25314578 0,26027505 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,25314578 0,26015875 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,25314578 0,26004256 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,25879937 0,26573149 ! T cell activation GO:0042110 134 79 0,000 0,25879937 0,26561291 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,25879937 0,26549444 ! chromatin assembly GO:0031497 102 80 0,000 0,26161033 0,26825848 GO:0006334|nucleosome assembly, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,26161033 0,26813893 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,26161033 0,26801949 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,26161033 0,26790016 ! hemostasis GO:0007599 125 81 0,000 0,2644108 0,27064746 ! mRNA transport GO:0051028 121 81 0,000 0,2644108 0,27052706 ! response to protein stimulus GO:0051789 111 81 0,000 0,2644108 0,27040677 ! regulation of neurological system process GO:0031644 122 81 0,000 0,2644108 0,27028659 ! vitamin metabolic process GO:0006766 103 81 0,000 0,2644108 0,27016652 ! detection of stimulus GO:0051606 108 82 0,000 0,2672008 0,27289602 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,26998039 0,27561247 ! regulation of defense response GO:0031347 117 84 0,000 0,27274959 0,2783159 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,27274959 0,27819248 ! sterol metabolic process GO:0016125 120 84 0,000 0,27274959 0,27806917 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,27550844 0,28075738 ! rRNA metabolic process GO:0016072 107 85 0,000 0,27550844 0,28063304 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,27550844 0,28050881 ! regulation of protein localization GO:0032880 132 85 0,000 0,27550844 0,28038469 ! regulation of membrane potential GO:0042391 128 85 0,000 0,27550844 0,28026069 ! nucleosome organization GO:0034728 114 87 0,000 0,28099526 0,28571578 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,28099526 0,28558953 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,28099526 0,28546338 ! female pregnancy GO:0007565 130 87 0,000 0,28099526 0,28533735 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,28099526 0,28521143 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,2837233 0,28785337 ! establishment of RNA localization GO:0051236 128 88 0,000 0,2837233 0,28772645 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,2837233 0,28759965 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,28644115 0,29022672 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,28644115 0,29009892 ! regulation of T cell activation GO:0050863 128 89 0,000 0,28644115 0,28997124 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,28914884 0,29258352 ! hormone metabolic process GO:0042445 121 90 0,000 0,28914884 0,29245485 ! RNA localization GO:0006403 135 91 0,000 0,29184642 0,29505352 ! ATP metabolic process GO:0046034 137 91 0,000 0,29184642 0,29492388 ! response to virus GO:0009615 122 91 0,000 0,29184642 0,29479436 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,29453391 0,29737839 ! cell fate commitment GO:0045165 141 92 0,000 0,29453391 0,29724791 ! positive regulation of immune response GO:0050778 121 92 0,000 0,29453391 0,29711754 ! DNA recombination GO:0006310 146 92 0,000 0,29453391 0,29698728 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,29721135 0,2995557 ! electron transport chain GO:0022900 123 94 0,000 0,29987879 0,30211179 ! carboxylic acid transport GO:0046942 147 95 0,000 0,30253625 0,30465559 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,30518378 0,30718718 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,30518378 0,3070528 ! protein maturation GO:0051604 129 96 0,000 0,30518378 0,30691854 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,30782141 0,30943586 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,30782141 0,30930068 ! calcium ion transport GO:0006816 167 99 0,000 0,31306713 0,31443423 ! extracellular structure organization GO:0043062 156 99 0,000 0,31306713 0,31429699 ! protein import GO:0017038 156 99 0,000 0,31306713 0,31415986 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,31306713 0,31402285 ! regulation of translation GO:0006417 151 100 0,000 0,31567528 0,31650094 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,31567528 0,31636303 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,31567528 0,31622524 ! divalent metal ion transport GO:0070838 171 100 0,000 0,31567528 0,31608757 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,31567528 0,31595002 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,31567528 0,31581259 ! protein localization in organelle GO:0033365 161 100 0,000 0,31567528 0,31567528