pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1289-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 3,000 1,181E-09 2,717E-06 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 3,000 8,028E-08 9,233E-05 ! positive regulation of vasoconstriction GO:0045907 9 5 2,000 8,702E-08 6,671E-05 ! positive regulation of microtubule polymerization GO:0031116 9 5 2,000 8,702E-08 5,003E-05 ! gas homeostasis GO:0033483 11 6 2,000 1,738E-07 7,994E-05 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 2,000 1,738E-07 6,662E-05 ! regulation of microtubule polymerization GO:0031113 11 6 2,000 1,738E-07 5,71E-05 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 2,000 3,037E-07 8,731E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 4,852E-07 1,24E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 4,852E-07 1,116E-04 ! mammary gland development GO:0030879 57 31 3,000 5,128E-07 1,072E-04 ! regulation of epithelial cell differentiation GO:0030856 13 9 2,000 7,267E-07 1,393E-04 ! positive regulation of protein polymerization GO:0032273 15 9 2,000 7,267E-07 1,286E-04 ! protein homooligomerization GO:0051260 52 35 3,000 8,482E-07 1,393E-04 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 1,037E-06 1,589E-04 ! Wnt receptor signaling pathway GO:0016055 130 87 4,000 1,045E-06 1,502E-04 ! gland morphogenesis GO:0022612 23 12 2,000 1,895E-06 2,564E-04 ! positive regulation of protein complex assembly GO:0031334 19 13 2,000 2,46E-06 3,143E-04 ! lipid localization GO:0010876 24 13 2,000 2,46E-06 2,978E-04 GO:0019915|lipid storage, ! negative regulation of endothelial cell proliferation GO:0001937 29 14 2,000 3,126E-06 3,595E-04 ! regulation of vasodilation GO:0042312 24 15 2,000 3,902E-06 4,274E-04 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 5,764E-06 6,026E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 5,814E-06 5,814E-04 ! inactivation of MAPK activity GO:0000188 27 17 2,000 5,814E-06 5,572E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 6,19E-06 5,694E-04 ! negative regulation of kinase activity GO:0033673 100 58 3,000 6,638E-06 5,872E-04 ! positive regulation of cytoskeleton organization GO:0051495 33 18 2,000 6,967E-06 5,935E-04 ! negative regulation of transferase activity GO:0051348 105 61 3,000 8,128E-06 6,677E-04 ! regulation of fatty acid metabolic process GO:0019217 28 19 2,000 8,261E-06 6,552E-04 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 8,261E-06 6,334E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 2,000 8,261E-06 6,129E-04 ! protein oligomerization GO:0051259 100 65 3,000 1,048E-05 7,534E-04 ! regulation of vasoconstriction GO:0019229 31 21 2,000 1,131E-05 7,88E-04 ! vasculogenesis GO:0001570 33 22 2,000 1,307E-05 8,843E-04 ! regulation of smooth muscle contraction GO:0006940 36 22 2,000 1,307E-05 8,59E-04 ! membrane depolarization GO:0051899 35 22 2,000 1,307E-05 8,352E-04 ! regulation of blood coagulation GO:0030193 34 22 2,000 1,307E-05 8,126E-04 ! regulation of peptidase activity GO:0052547 106 72 3,000 1,576E-05 9,539E-04 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 1,713E-05 1,01E-03 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 1,713E-05 9,85E-04 ! regulation of cellular ketone metabolic process GO:0010565 34 25 2,000 1,944E-05 1,09E-03 ! gland development GO:0048732 148 77 3,000 2,057E-05 1,127E-03 ! negative regulation of protein kinase cascade GO:0010741 51 26 2,000 2,194E-05 1,174E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 2,000 2,194E-05 1,147E-03 ! regulation of coagulation GO:0050818 39 26 2,000 2,194E-05 1,121E-03 ! cholesterol homeostasis GO:0042632 46 28 2,000 2,757E-05 1,378E-03 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 2,000 2,757E-05 1,349E-03 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 2,757E-05 1,321E-03 ! skeletal muscle tissue development GO:0007519 123 87 3,000 3,333E-05 1,565E-03 GO:0060538|skeletal muscle organ development, ! cholesterol transport GO:0030301 46 30 2,000 3,406E-05 1,567E-03 GO:0015918|sterol transport, ! regulation of microtubule-based process GO:0032886 58 30 2,000 3,406E-05 1,536E-03 ! neutral lipid metabolic process GO:0006638 41 32 2,000 4,149E-05 1,835E-03 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 55 33 2,000 4,558E-05 1,978E-03 ! regulation of response to external stimulus GO:0032101 139 96 3,000 4,908E-05 2,09E-03 ! glycerol ether metabolic process GO:0006662 44 34 2,000 4,991E-05 2,087E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 4,991E-05 2,05E-03 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 5,451E-05 2,2E-03 ! calcium ion transport GO:0006816 167 99 3,000 5,536E-05 2,195E-03 ! divalent metal ion transport GO:0070838 171 100 3,000 5,758E-05 2,245E-03 ! organic ether metabolic process GO:0018904 46 36 2,000 5,938E-05 2,276E-03 ! tissue remodeling GO:0048771 62 36 2,000 5,938E-05 2,239E-03 ! male meiosis GO:0007140 7 6 1,000 6,503E-05 2,412E-03 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 6,503E-05 2,374E-03 ! ER overload response GO:0006983 7 6 1,000 6,503E-05 2,337E-03 ! positive regulation of insulin secretion GO:0032024 8 6 1,000 6,503E-05 2,301E-03 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 6,503E-05 2,266E-03 ! positive regulation of protein transport GO:0051222 55 40 2,000 8,169E-05 2,804E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 9,092E-05 3,075E-03 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 9,092E-05 3,031E-03 ! vesicle fusion GO:0006906 15 7 1,000 9,092E-05 2,987E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 9,092E-05 2,945E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 9,465E-05 3,023E-03 ! regulation of JAK-STAT cascade GO:0046425 61 42 2,000 9,465E-05 2,982E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,016E-04 3,158E-03 ! vesicle organization GO:0016050 79 43 2,000 1,016E-04 3,116E-03 ! response to insulin stimulus GO:0032868 63 43 2,000 1,016E-04 3,075E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,211E-04 3,616E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,211E-04 3,57E-03 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 1,211E-04 3,525E-03 ! regulation of smoothened signaling pathway GO:0008589 13 8 1,000 1,211E-04 3,481E-03 ! response to UV GO:0009411 75 46 2,000 1,244E-04 3,533E-03 ! regulation of protein polymerization GO:0032271 71 47 2,000 1,327E-04 3,723E-03 ! regulation of muscle contraction GO:0006937 69 48 2,000 1,414E-04 3,917E-03 ! regulation of intracellular transport GO:0032386 78 49 2,000 1,504E-04 4,117E-03 ! positive regulation of peptide secretion GO:0002793 15 9 1,000 1,554E-04 4,206E-03 ! regulation of hormone metabolic process GO:0032350 15 9 1,000 1,554E-04 4,157E-03 ! localization within membrane GO:0051668 15 9 1,000 1,554E-04 4,11E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 1,695E-04 4,429E-03 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,695E-04 4,379E-03 ! positive regulation of organelle organization GO:0010638 82 51 2,000 1,695E-04 4,331E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,941E-04 4,905E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,941E-04 4,851E-03 ! regulation of protein complex assembly GO:0043254 81 54 2,000 2,01E-04 4,97E-03 ! positive regulation of cell motion GO:0051272 99 56 2,000 2,239E-04 5,479E-03 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 2,36E-04 5,714E-03 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,369E-04 5,675E-03 ! cell-cell junction assembly GO:0007043 18 12 1,000 2,839E-04 6,731E-03 ! organelle fusion GO:0048284 28 13 1,000 3,35E-04 7,863E-03 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 3,35E-04 7,783E-03 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 3,35E-04 7,705E-03 ! regulation of RNA stability GO:0043487 28 13 1,000 3,35E-04 7,629E-03 ! regulation of MAPKKK cascade GO:0043408 101 65 2,000 3,483E-04 7,853E-03 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 3,903E-04 8,716E-03 ! negative regulation of inflammatory response GO:0050728 16 14 1,000 3,903E-04 8,632E-03 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 3,903E-04 8,55E-03 ! lipid phosphorylation GO:0046834 23 15 1,000 4,498E-04 9,759E-03 ! myoblast differentiation GO:0045445 27 15 1,000 4,498E-04 9,668E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 4,498E-04 9,579E-03 ! response to hypoxia GO:0001666 132 72 2,000 4,707E-04 9,932E-03 ! response to oxygen levels GO:0070482 137 74 2,000 5,101E-04 0,01066621 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 5,101E-04 0,01057011 ! regulation of protein transport GO:0051223 114 76 2,000 5,516E-04 0,01132768 GO:0070201|regulation of establishment of protein localization, ! negative regulation of defense response GO:0031348 19 17 1,000 5,81E-04 0,01182609 ! positive regulation of hormone secretion GO:0046887 24 17 1,000 5,81E-04 0,01172235 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 5,81E-04 0,01162042 ! peptidyl-serine modification GO:0018209 27 17 1,000 5,81E-04 0,01152024 ! cell-cell junction organization GO:0045216 25 17 1,000 5,81E-04 0,01142178 ! pancreas development GO:0031016 26 18 1,000 6,528E-04 0,01272363 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 7,286E-04 0,01408224 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 7,286E-04 0,01396489 ! regulation of protein localization GO:0032880 132 85 2,000 7,649E-04 0,01453986 ! regulation of membrane potential GO:0042391 128 85 2,000 7,649E-04 0,01442068 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 7,649E-04 0,01430344 ! cell cycle arrest GO:0007050 150 86 2,000 7,914E-04 0,01467956 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 7,914E-04 0,01456213 ! positive regulation of B cell activation GO:0050871 31 20 1,000 8,085E-04 0,01475798 ! interphase GO:0051325 159 88 2,000 8,462E-04 0,01532401 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 8,924E-04 0,0160352 ! vesicle docking GO:0048278 27 21 1,000 8,924E-04 0,01591089 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 8,924E-04 0,0157885 ! regulation of insulin secretion GO:0050796 26 21 1,000 8,924E-04 0,01566798 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 8,924E-04 0,01554928 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 9,803E-04 0,016953 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 9,934E-04 0,01705013 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 1,072E-03 0,01826814 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 1,072E-03 0,01813382 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 1,072E-03 0,01800145 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 1,089E-03 0,01814977 ! response to light stimulus GO:0009416 153 96 2,000 1,089E-03 0,0180192 ! fat cell differentiation GO:0045444 37 24 1,000 1,168E-03 0,01919155 ! negative regulation of cell development GO:0010721 56 24 1,000 1,168E-03 0,01905544 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 1,168E-03 0,01892125 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 1,268E-03 0,02039556 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of peptide secretion GO:0002791 34 25 1,000 1,268E-03 0,02025393 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,372E-03 0,02176143 ! membrane docking GO:0022406 39 27 1,000 1,48E-03 0,0233103 ! negative regulation of response to external stimulus GO:0032102 37 28 1,000 1,591E-03 0,02489946 ! cell junction assembly GO:0034329 56 28 1,000 1,591E-03 0,02473122 ! regulation of B cell activation GO:0050864 42 28 1,000 1,591E-03 0,02456523 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 1,707E-03 0,02617411 ! calcium-mediated signaling GO:0019722 50 32 1,000 2,077E-03 0,0316379 ! cell junction organization GO:0034330 63 33 1,000 2,208E-03 0,03341299 ! carbohydrate homeostasis GO:0033500 39 33 1,000 2,208E-03 0,0331946 GO:0042593|glucose homeostasis, ! androgen receptor signaling pathway GO:0030521 54 33 1,000 2,208E-03 0,03297906 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 2,343E-03 0,03476789 ! glycogen metabolic process GO:0005977 48 35 1,000 2,482E-03 0,03658994 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 2,482E-03 0,03635689 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of hormone secretion GO:0046883 48 36 1,000 2,624E-03 0,03820104 ! glucan metabolic process GO:0044042 49 36 1,000 2,624E-03 0,03796078 GO:0006073|cellular glucan metabolic process, ! mesenchymal cell development GO:0014031 64 38 1,000 2,921E-03 0,04198284 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 3,074E-03 0,04391889 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 3,232E-03 0,04588399 ! energy reserve metabolic process GO:0006112 59 41 1,000 3,393E-03 0,04787739 ! regulation of inflammatory response GO:0050727 60 44 1,000 3,899E-03 0,05467892 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 3,899E-03 0,05434754 ! positive regulation of cell cycle GO:0045787 77 45 1,000 4,075E-03 0,05645764 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 4,075E-03 0,05611957 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 4,438E-03 0,06075166 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 4,624E-03 0,06293429 ! skeletal muscle fiber development GO:0048741 73 50 1,000 5,009E-03 0,06776395 ! membrane fusion GO:0006944 80 50 1,000 5,009E-03 0,06736766 ! lipid modification GO:0030258 73 50 1,000 5,009E-03 0,06697599 ! positive regulation of secretion GO:0051047 71 51 1,000 5,206E-03 0,0692148 ! activation of phospholipase C activity GO:0007202 87 51 1,000 5,206E-03 0,06881702 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 5,206E-03 0,06842378 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 5,407E-03 0,07066254 ! regulation of phospholipase activity GO:0010517 90 54 1,000 5,82E-03 0,07562614 ! positive regulation of lipase activity GO:0060193 90 54 1,000 5,82E-03 0,07520127 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 6,247E-03 0,08026399 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 6,687E-03 0,08544785 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 7,142E-03 0,09074936 ! meiosis GO:0007126 96 61 1,000 7,374E-03 0,09318644 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cell growth GO:0030308 106 62 1,000 7,61E-03 0,09563958 ! meiotic cell cycle GO:0051321 97 62 1,000 7,61E-03 0,0951198 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 7,849E-03 0,09757803 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 7,849E-03 0,09705342 ! regulation of lipase activity GO:0060191 109 63 1,000 7,849E-03 0,09653441 ! negative regulation of cell size GO:0045792 108 64 1,000 8,091E-03 0,09898709 ! regulation of caspase activity GO:0043281 97 65 1,000 8,337E-03 0,10145463 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 8,839E-03 0,10699281 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 9,616E-03 0,1157917 ! muscle cell differentiation GO:0042692 104 71 1,000 9,881E-03 0,11837057 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,01015025 0,12096148 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01053881 0,12494471 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01053881 0,12430397 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01053881 0,12366976 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01053881 0,123042 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01053881 0,12242057 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01053881 0,12180539 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01053881 0,12119637 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01053881 0,1205934 ! sleep GO:0030431 11 5 0,000 0,01053881 0,1199964 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01053881 0,11940529 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01053881 0,11881997 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01053881 0,11824036 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01053881 0,11766637 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01053881 0,11709794 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01053881 0,11653497 ! tongue development GO:0043586 6 5 0,000 0,01053881 0,11597738 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01053881 0,11542511 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01053881 0,11487807 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01053881 0,11433619 ! cobalt ion transport GO:0006824 9 5 0,000 0,01053881 0,1137994 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01053881 0,11326763 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01053881 0,11274081 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01053881 0,11221886 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01053881 0,11170172 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01053881 0,11118933 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01053881 0,11068161 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01053881 0,11017851 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01053881 0,10967997 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01053881 0,10918592 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01053881 0,10869629 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01053881 0,10821104 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01053881 0,1077301 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01053881 0,10725342 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01053881 0,10678094 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01053881 0,1063126 ! malate metabolic process GO:0006108 7 5 0,000 0,01053881 0,10584835 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01053881 0,10538814 ! behavioral response to pain GO:0048266 7 5 0,000 0,01053881 0,10493192 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01053881 0,10447963 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01053881 0,10403122 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01053881 0,10358664 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01053881 0,10314584 ! mating behavior GO:0007617 6 5 0,000 0,01053881 0,10270878 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01053881 0,10227541 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01053881 0,10184569 ! rhythmic behavior GO:0007622 12 5 0,000 0,01053881 0,10141955 ! copulation GO:0007620 7 5 0,000 0,01053881 0,10099697 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01053881 0,1005779 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01053881 0,10016229 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01053881 0,0997501 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01053881 0,09934128 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01053881 0,09893581 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01053881 0,09853363 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01053881 0,09813471 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01053881 0,097739 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01053881 0,09734648 ! response to protozoan GO:0001562 9 5 0,000 0,01053881 0,09695709 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01053881 0,09657081 ! lymph vessel development GO:0001945 7 5 0,000 0,01053881 0,09618759 ! endochondral ossification GO:0001958 12 5 0,000 0,01053881 0,0958074 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01053881 0,09543021 ! parathyroid gland development GO:0060017 8 5 0,000 0,01053881 0,09505597 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01053881 0,09468466 ! anagen GO:0042640 6 5 0,000 0,01053881 0,09431624 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01053881 0,09395067 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01053881 0,09358793 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01053881 0,09322797 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01053881 0,09287078 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01053881 0,09251631 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01053881 0,09216454 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01053881 0,09181543 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01053881 0,09146896 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01053881 0,09112509 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01053881 0,09078379 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01053881 0,09044505 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01053881 0,09010882 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01053881 0,08977509 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01053881 0,08944381 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01053881 0,08911498 ! ovulation GO:0030728 6 5 0,000 0,01053881 0,08878855 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01053881 0,0884645 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01053881 0,08814281 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01053881 0,08782345 ! response to pH GO:0009268 9 5 0,000 0,01053881 0,0875064 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01053881 0,08719163 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01053881 0,08687912 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01053881 0,08656883 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01053881 0,08626076 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01053881 0,08595487 ! polyol catabolic process GO:0046174 7 5 0,000 0,01053881 0,08565114 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01053881 0,08534955 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01053881 0,08505008 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01053881 0,0847527 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01053881 0,0844574 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01053881 0,08416414 ! urea metabolic process GO:0019627 6 5 0,000 0,01053881 0,08387292 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01053881 0,0835837 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01053881 0,08329647 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01053881 0,08301121 ! neutrophil activation GO:0042119 5 5 0,000 0,01053881 0,08272789 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01053881 0,08244651 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01053881 0,08216703 ! response to food GO:0032094 5 5 0,000 0,01053881 0,08188944 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01053881 0,08161371 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01053881 0,08133984 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01053881 0,0810678 ! forebrain neuron development GO:0021884 7 5 0,000 0,01053881 0,08079758 ! melanosome organization GO:0032438 7 5 0,000 0,01053881 0,08052915 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01053881 0,08026249 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01053881 0,0799976 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01053881 0,07973445 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01053881 0,07947303 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01053881 0,07921331 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01053881 0,07895529 ! nucleoside transport GO:0015858 6 5 0,000 0,01053881 0,07869894 ! nucleoside salvage GO:0043174 7 5 0,000 0,01053881 0,07844425 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01053881 0,0781912 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01053881 0,07793979 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01053881 0,07768998 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01053881 0,07744177 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01053881 0,07719514 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01053881 0,07695007 ! depyrimidination GO:0045008 8 5 0,000 0,01053881 0,07670656 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01053881 0,07646458 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01053881 0,07622413 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01053881 0,07598518 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01053881 0,07574773 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01053881 0,07551175 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01053881 0,07527725 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01053881 0,07504419 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01053881 0,07481257 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01053881 0,07458238 ! monocyte differentiation GO:0030224 8 5 0,000 0,01053881 0,0743536 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01053881 0,07412622 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01053881 0,07390022 ! centrosome duplication GO:0051298 5 5 0,000 0,01053881 0,0736756 ! response to UV-C GO:0010225 6 5 0,000 0,01053881 0,07345234 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01053881 0,07323043 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01053881 0,07300986 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01053881 0,07279061 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01053881 0,07257267 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01053881 0,07235604 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01053881 0,07214069 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01053881 0,07192663 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01053881 0,07171383 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01053881 0,07150228 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01053881 0,07129198 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01053881 0,07108291 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01053881 0,07087507 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01053881 0,07066844 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01053881 0,070463 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01053881 0,07025876 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01053881 0,0700557 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01053881 0,06985381 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01053881 0,06965308 ! neural tube patterning GO:0021532 6 5 0,000 0,01053881 0,0694535 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01053881 0,06925507 ! histone demethylation GO:0016577 9 5 0,000 0,01053881 0,06905776 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01053881 0,06886157 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01053881 0,0686665 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01053881 0,06847252 ! enteric nervous system development GO:0048484 8 5 0,000 0,01053881 0,06827964 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01053881 0,06808785 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01053881 0,06789712 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01053881 0,06770747 ! transcription termination GO:0006353 8 5 0,000 0,01053881 0,06751887 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01053881 0,06733131 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01053881 0,0671448 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01053881 0,06695932 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01053881 0,06677486 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01053881 0,06659141 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01053881 0,06640897 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01053881 0,06622752 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01053881 0,06604707 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01053881 0,06586759 ! apical protein localization GO:0045176 6 5 0,000 0,01053881 0,06568909 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01053881 0,06551155 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01053881 0,06533497 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01053881 0,06515934 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01053881 0,06498465 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01053881 0,06481089 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01053881 0,06463806 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01053881 0,06446615 ! glial cell migration GO:0008347 10 5 0,000 0,01053881 0,06429515 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01053881 0,06412506 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01053881 0,06395587 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01053881 0,06378756 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01053881 0,06362014 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01053881 0,06345359 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01053881 0,06328792 ! neural plate development GO:0001840 6 5 0,000 0,01053881 0,06312311 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01053881 0,06295915 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01053881 0,06279604 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01053881 0,06263378 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01053881 0,06247235 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01053881 0,06231176 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01053881 0,06215198 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01053881 0,06199303 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01053881 0,06183488 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01053881 0,06167754 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01053881 0,061521 ! spindle assembly GO:0051225 5 5 0,000 0,01053881 0,06136525 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01053881 0,06121029 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01053881 0,0610561 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01053881 0,0609027 ! organ regeneration GO:0031100 7 5 0,000 0,01053881 0,06075006 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01053881 0,06059818 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01053881 0,06044707 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01053881 0,0602967 GO:0055081|anion homeostasis, ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,0106977 0,06105387 ! negative regulation of growth GO:0045926 123 75 1,000 0,01097625 0,06248856 ! ATP biosynthetic process GO:0006754 118 79 1,000 0,01212228 0,06884257 ! tRNA transcription GO:0009304 11 6 0,000 0,01263357 0,07156949 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01263357 0,07139365 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01263357 0,07121866 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01263357 0,07104453 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01263357 0,07087125 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01263357 0,07069882 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01263357 0,07052722 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01263357 0,07035645 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01263357 0,07018651 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01263357 0,07001738 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01263357 0,06984907 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01263357 0,06968157 ! prostate gland development GO:0030850 9 6 0,000 0,01263357 0,06951487 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01263357 0,06934896 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01263357 0,06918384 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01263357 0,06901951 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01263357 0,06885596 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01263357 0,06869318 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01263357 0,06853116 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01263357 0,06836991 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01263357 0,06820942 ! neuron adhesion GO:0007158 9 6 0,000 0,01263357 0,06804968 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01263357 0,06789069 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01263357 0,06773243 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01263357 0,06757492 ! signal peptide processing GO:0006465 8 6 0,000 0,01263357 0,06741813 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01263357 0,06726207 ! mRNA stabilization GO:0048255 15 6 0,000 0,01263357 0,06710673 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01263357 0,06695211 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01263357 0,06679819 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01263357 0,06664499 ! opsonization GO:0008228 8 6 0,000 0,01263357 0,06649248 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01263357 0,06634067 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01263357 0,06618955 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01263357 0,06603912 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01263357 0,06588937 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01263357 0,0657403 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01263357 0,0655919 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01263357 0,06544418 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01263357 0,06529711 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01263357 0,0651507 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01263357 0,06500495 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01263357 0,06485985 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01263357 0,0647154 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01263357 0,06457159 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01263357 0,06442841 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01263357 0,06428587 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01263357 0,06414396 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01263357 0,06400267 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01263357 0,06386201 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01263357 0,06372196 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01263357 0,06358252 ! thymic T cell selection GO:0045061 12 6 0,000 0,01263357 0,0634437 ! protein lipoylation GO:0009249 10 6 0,000 0,01263357 0,06330548 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01263357 0,06316786 ! pigment granule organization GO:0048753 11 6 0,000 0,01263357 0,06303083 ! drug transport GO:0015893 6 6 0,000 0,01263357 0,0628944 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01263357 0,06275856 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01263357 0,06262331 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01263357 0,06248863 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01263357 0,06235454 ! histidine metabolic process GO:0006547 6 6 0,000 0,01263357 0,06222101 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01263357 0,06208806 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01263357 0,06195568 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01263357 0,06182386 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01263357 0,0616926 ! adenohypophysis development GO:0021984 10 6 0,000 0,01263357 0,06156189 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01263357 0,06143174 ! hyperosmotic response GO:0006972 8 6 0,000 0,01263357 0,06130214 ! microtubule nucleation GO:0007020 10 6 0,000 0,01263357 0,06117308 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01263357 0,06104457 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01263357 0,06091659 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01263357 0,06078915 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01263357 0,06066224 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01263357 0,06053586 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01263357 0,06041001 ! response to dietary excess GO:0002021 7 6 0,000 0,01263357 0,06028468 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01263357 0,06015986 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01263357 0,06003557 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01263357 0,05991178 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01263357 0,05978851 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01263357 0,05966574 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01263357 0,05954347 ! neuron apoptosis GO:0051402 8 6 0,000 0,01263357 0,05942171 ! organic alcohol transport GO:0015850 9 6 0,000 0,01263357 0,05930044 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01263357 0,05917966 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01263357 0,05905938 ! male sex determination GO:0030238 9 6 0,000 0,01263357 0,05893958 ! carnitine transport GO:0015879 8 6 0,000 0,01263357 0,05882027 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01263357 0,05870144 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01263357 0,05858309 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01263357 0,05846522 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01263357 0,05834782 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01263357 0,05823089 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01263357 0,05811443 ! parturition GO:0007567 12 6 0,000 0,01263357 0,05799843 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01263357 0,0578829 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01263357 0,05776782 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01263357 0,0576532 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01263357 0,05753904 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01263357 0,05742532 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01263357 0,05731206 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01263357 0,05719924 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01263357 0,05708686 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01263357 0,05697493 ! macrophage differentiation GO:0030225 10 6 0,000 0,01263357 0,05686343 ! astrocyte development GO:0014002 14 6 0,000 0,01263357 0,05675237 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01263357 0,05664174 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01263357 0,05653154 ! interaction with symbiont GO:0051702 8 6 0,000 0,01263357 0,05642177 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01263357 0,05631243 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01263357 0,05620351 ! eating behavior GO:0042755 6 6 0,000 0,01263357 0,05609501 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01263357 0,05598692 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01263357 0,05587926 ! response to copper ion GO:0046688 9 6 0,000 0,01263357 0,055772 ! DNA topological change GO:0006265 8 6 0,000 0,01263357 0,05566516 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01263357 0,05555873 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01263357 0,0554527 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01263357 0,05534707 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01263357 0,05524185 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01263357 0,05513703 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01263357 0,0550326 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01263357 0,05492857 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01263357 0,05482493 ! hair follicle maturation GO:0048820 7 6 0,000 0,01263357 0,05472168 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01263357 0,05461882 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01263357 0,05451635 ! Schwann cell development GO:0014044 14 6 0,000 0,01263357 0,05441426 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01263357 0,05431255 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01263357 0,05421122 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01263357 0,05411027 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01263357 0,05400969 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01263357 0,05390949 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01263357 0,05380966 ! histone ubiquitination GO:0016574 7 6 0,000 0,01263357 0,05371019 ! regulation of meiosis GO:0040020 10 6 0,000 0,01263357 0,0536111 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01263357 0,05351236 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01263357 0,053414 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01263357 0,05331599 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01263357 0,05321834 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01263357 0,05312105 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01263357 0,05302411 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01263357 0,05292753 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01263357 0,0528313 ! receptor internalization GO:0031623 9 6 0,000 0,01263357 0,05273542 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01263357 0,05263988 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01263357 0,05254469 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01263357 0,05244984 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01263357 0,05235534 ! protein deubiquitination GO:0016579 8 6 0,000 0,01263357 0,05226118 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01263357 0,05216735 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01263357 0,05207386 ! axonal fasciculation GO:0007413 9 6 0,000 0,01263357 0,0519807 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01263357 0,05188788 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01263357 0,05179539 ! midbrain development GO:0030901 6 6 0,000 0,01263357 0,05170323 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01263357 0,05161139 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01263357 0,05151988 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01263357 0,0514287 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01263357 0,05133783 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01263357 0,05124729 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01263357 0,05115707 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01263357 0,05106716 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01263357 0,05097757 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01263357 0,05088829 ! adult feeding behavior GO:0008343 6 6 0,000 0,01263357 0,05079932 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01263357 0,05071067 ! blastocyst growth GO:0001832 15 6 0,000 0,01263357 0,05062232 ! pigment granule transport GO:0051904 12 6 0,000 0,01263357 0,05053428 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01263357 0,05044655 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01263357 0,05035912 ! catecholamine transport GO:0051937 7 6 0,000 0,01263357 0,050272 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01263357 0,05018517 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01263357 0,05009864 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01263357 0,05001242 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01263357 0,04992648 ! protein prenylation GO:0018342 10 6 0,000 0,01263357 0,04984085 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01263357 0,0497555 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01263357 0,04967045 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01263357 0,04958569 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01271419 0,04981711 GO:0002696|positive regulation of leukocyte activation, ! mRNA transport GO:0051028 121 81 1,000 0,01271419 0,04973239 ! ossification GO:0001503 134 82 1,000 0,01301483 0,0508219 GO:0060348|bone development, ! regulation of defense response GO:0031347 117 84 1,000 0,01362538 0,05311588 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,01393527 0,05423201 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 1,000 0,01456421 0,05658393 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01472401 0,05710831 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01472401 0,05701217 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01472401 0,05691635 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01472401 0,05682085 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01472401 0,05672568 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01472401 0,05663082 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01472401 0,05653628 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01472401 0,05644205 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01472401 0,05634814 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01472401 0,05625453 ! reproductive behavior GO:0019098 12 7 0,000 0,01472401 0,05616124 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01472401 0,05606826 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01472401 0,05597559 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01472401 0,05588322 ! oligopeptide transport GO:0006857 11 7 0,000 0,01472401 0,05579115 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01472401 0,05569939 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01472401 0,05560793 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,01472401 0,05551677 ! pericardium development GO:0060039 8 7 0,000 0,01472401 0,05542591 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01472401 0,05533534 ! fibril organization GO:0043206 13 7 0,000 0,01472401 0,05524507 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01472401 0,0551551 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01472401 0,05506541 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01472401 0,05497602 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01472401 0,05488692 ! lipoprotein transport GO:0042953 9 7 0,000 0,01472401 0,05479811 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01472401 0,05470958 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01472401 0,05462134 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01472401 0,05453338 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01472401 0,05444571 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01472401 0,05435831 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01472401 0,0542712 ! chemosensory behavior GO:0007635 9 7 0,000 0,01472401 0,05418437 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01472401 0,05409781 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01472401 0,05401153 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01472401 0,05392552 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01472401 0,05383979 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01472401 0,05375433 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01472401 0,05366914 ! reflex GO:0060004 12 7 0,000 0,01472401 0,05358422 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01472401 0,05349957 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01472401 0,05341519 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01472401 0,05333107 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01472401 0,05324722 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01472401 0,05316363 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01472401 0,0530803 ! spinal cord patterning GO:0021511 7 7 0,000 0,01472401 0,05299723 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01472401 0,05291442 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01472401 0,05283187 ! adrenal gland development GO:0030325 17 7 0,000 0,01472401 0,05274958 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01472401 0,05266754 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01472401 0,05258576 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01472401 0,05250423 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01472401 0,05242296 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01472401 0,05234193 ! endosome organization GO:0007032 10 7 0,000 0,01472401 0,05226116 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01472401 0,05218063 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01472401 0,05210035 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01472401 0,05202032 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01472401 0,05194054 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01472401 0,05186099 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01472401 0,0517817 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01472401 0,05170264 ! galactose metabolic process GO:0006012 10 7 0,000 0,01472401 0,05162383 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01472401 0,05154525 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01472401 0,05146691 ! organ growth GO:0035265 11 7 0,000 0,01472401 0,05138882 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01472401 0,05131095 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01472401 0,05123333 ! retinol metabolic process GO:0042572 9 7 0,000 0,01472401 0,05115594 ! behavioral fear response GO:0001662 13 7 0,000 0,01472401 0,05107878 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01472401 0,05100185 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01472401 0,05092516 ! rRNA modification GO:0000154 12 7 0,000 0,01472401 0,05084869 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01472401 0,05077246 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01472401 0,05069645 ! response to UV-B GO:0010224 11 7 0,000 0,01472401 0,05062067 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01472401 0,05054512 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01472401 0,05046979 ! intermediate filament organization GO:0045109 11 7 0,000 0,01472401 0,05039469 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01472401 0,05031981 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01472401 0,05024515 ! fibrinolysis GO:0042730 9 7 0,000 0,01472401 0,05017071 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01472401 0,05009649 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01472401 0,0500225 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01472401 0,04994872 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01472401 0,04987515 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01472401 0,04980181 ! response to tropane GO:0014073 13 7 0,000 0,01472401 0,04972868 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01472401 0,04965576 ! melanosome localization GO:0032400 10 7 0,000 0,01472401 0,04958306 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01472401 0,04951057 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01472401 0,04943829 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01472401 0,04936622 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01472401 0,04929437 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01472401 0,04922272 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01472401 0,04915128 ! mast cell activation GO:0045576 9 7 0,000 0,01472401 0,04908004 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01472401 0,04900902 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01472401 0,04893819 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01472401 0,04886758 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01472401 0,04879716 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01472401 0,04872695 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01472401 0,04865694 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01472401 0,04858713 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01472401 0,04851752 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01472401 0,04844811 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01472401 0,0483789 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01472401 0,04830989 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01472401 0,04824107 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01472401 0,04817245 ! response to tumor cell GO:0002347 12 7 0,000 0,01472401 0,04810402 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01472401 0,04803579 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01472401 0,04796775 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01472401 0,0478999 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01472401 0,04783225 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01472401 0,04776478 ! diuresis GO:0030146 12 7 0,000 0,01472401 0,04769751 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01472401 0,04763042 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01472401 0,04756352 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01472401 0,04749682 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01472401 0,04743029 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01472401 0,04736396 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01472401 0,04729781 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01472401 0,04723184 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01472401 0,04716606 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01472401 0,04710046 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01472401 0,04703504 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01472401 0,04696981 ! lymph node development GO:0048535 9 7 0,000 0,01472401 0,04690475 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01472401 0,04683987 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01472401 0,04677518 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01472401 0,04671066 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01472401 0,04664632 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01472401 0,04658216 ! ATP catabolic process GO:0006200 10 7 0,000 0,01472401 0,04651817 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01472401 0,04645436 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01472401 0,04639073 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01472401 0,04632726 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01472401 0,04626397 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01472401 0,04620086 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01472401 0,04613791 ! muscle adaptation GO:0043500 12 7 0,000 0,01472401 0,04607514 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01472401 0,04601254 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01472401 0,04595011 ! retina homeostasis GO:0001895 9 7 0,000 0,01472401 0,04588784 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01472401 0,04582575 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01472401 0,04576382 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01472401 0,04570206 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01472401 0,04564047 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01472401 0,04557904 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01472401 0,04551778 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01472401 0,04545668 ! establishment of RNA localization GO:0051236 128 88 1,000 0,01488324 0,04588665 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 1,000 0,01488324 0,04582522 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,01520528 0,0467542 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 1,000 0,01520528 0,04669177 ! RNA localization GO:0006403 135 91 1,000 0,01585836 0,04863231 ! ATP metabolic process GO:0046034 137 91 1,000 0,01585836 0,04856755 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,01618938 0,04951538 ! cell fate commitment GO:0045165 141 92 1,000 0,01618938 0,04944962 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,01652335 0,0504028 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,01652335 0,05033605 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01681015 0,05114198 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01681015 0,05107443 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01681015 0,05100705 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01681015 0,05093984 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01681015 0,05087282 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01681015 0,05080597 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01681015 0,05073929 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01681015 0,05067279 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01681015 0,05060647 ! phosphate transport GO:0006817 10 8 0,000 0,01681015 0,05054031 ! N-glycan processing GO:0006491 12 8 0,000 0,01681015 0,05047433 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01681015 0,05040853 ! UTP metabolic process GO:0046051 8 8 0,000 0,01681015 0,05034289 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01681015 0,05027743 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01681015 0,05021213 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01681015 0,050147 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01681015 0,05008205 ! succinate metabolic process GO:0006105 14 8 0,000 0,01681015 0,05001726 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01681015 0,04995264 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01681015 0,04988818 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01681015 0,04982389 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01681015 0,04975977 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01681015 0,04969581 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01681015 0,04963202 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01681015 0,04956839 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01681015 0,04950492 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01681015 0,04944161 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01681015 0,04937847 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01681015 0,04931549 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01681015 0,04925266 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01681015 0,04919 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01681015 0,0491275 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01681015 0,04906515 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01681015 0,04900297 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01681015 0,04894094 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01681015 0,04887906 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01681015 0,04881735 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01681015 0,04875579 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01681015 0,04869438 ! melanin metabolic process GO:0006582 12 8 0,000 0,01681015 0,04863313 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01681015 0,04857204 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01681015 0,04851109 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01681015 0,0484503 ! macrophage activation GO:0042116 12 8 0,000 0,01681015 0,04838966 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01681015 0,04832918 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01681015 0,04826884 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01681015 0,04820865 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01681015 0,04814862 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01681015 0,04808873 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01681015 0,04802899 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01681015 0,0479694 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01681015 0,04790996 ! ruffle organization GO:0031529 11 8 0,000 0,01681015 0,04785067 ! osteoblast development GO:0002076 13 8 0,000 0,01681015 0,04779152 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01681015 0,04773252 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01681015 0,04767366 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01681015 0,04761495 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01681015 0,04755638 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01681015 0,04749796 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01681015 0,04743968 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01681015 0,04738154 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01681015 0,04732355 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01681015 0,0472657 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01681015 0,04720799 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01681015 0,04715042 ! segment specification GO:0007379 10 8 0,000 0,01681015 0,04709298 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01681015 0,04703569 ! cellular extravasation GO:0045123 11 8 0,000 0,01681015 0,04697854 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01681015 0,04692153 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01681015 0,04686465 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01681015 0,04680792 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01681015 0,04675132 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01681015 0,04669486 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01681015 0,04663853 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01681015 0,04658234 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01681015 0,04652628 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01681015 0,04647036 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01681015 0,04641457 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01681015 0,04635892 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01681015 0,0463034 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01681015 0,04624801 ! icosanoid secretion GO:0032309 12 8 0,000 0,01681015 0,04619276 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01681015 0,04613764 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01681015 0,04608265 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01681015 0,04602779 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01681015 0,04597306 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01681015 0,04591846 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01681015 0,04586399 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01681015 0,04580964 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01681015 0,04575543 ! sterol catabolic process GO:0016127 9 8 0,000 0,01681015 0,04570135 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01681015 0,04564739 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01681015 0,04559356 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01681015 0,04553986 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01681015 0,04548628 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01681015 0,04543283 ! prophase GO:0051324 11 8 0,000 0,01681015 0,04537951 ! S phase GO:0051320 8 8 0,000 0,01681015 0,04532631 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01681015 0,04527323 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01681015 0,04522028 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01681015 0,04516745 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01681015 0,04511475 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01681015 0,04506217 ! hormone catabolic process GO:0042447 13 8 0,000 0,01681015 0,04500971 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01681015 0,04495737 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01681015 0,04490516 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01681015 0,04485306 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01681015 0,04480109 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01681015 0,04474924 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01681015 0,0446975 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01681015 0,04464589 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01681015 0,04459439 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01681015 0,04454302 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01681015 0,04449176 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01681015 0,04444062 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01681015 0,0443896 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01681015 0,04433869 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01681015 0,0442879 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01681015 0,04423723 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01681015 0,04418667 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,01754294 0,04606023 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01889199 0,04954569 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01889199 0,04948926 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01889199 0,04943295 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01889199 0,04937678 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01889199 0,04932073 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01889199 0,04926481 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01889199 0,04920902 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01889199 0,04915336 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01889199 0,04909781 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01889199 0,0490424 ! GTP metabolic process GO:0046039 9 9 0,000 0,01889199 0,04898711 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01889199 0,04893194 ! social behavior GO:0035176 14 9 0,000 0,01889199 0,0488769 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01889199 0,04882198 ! artery development GO:0060840 19 9 0,000 0,01889199 0,04876719 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01889199 0,04871252 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01889199 0,04865797 ! response to pain GO:0048265 16 9 0,000 0,01889199 0,04860354 ! protein complex disassembly GO:0043241 17 9 0,000 0,01889199 0,04854924 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01889199 0,04849505 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01889199 0,04844099 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01889199 0,04838704 ! lung alveolus development GO:0048286 17 9 0,000 0,01889199 0,04833322 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01889199 0,04827952 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01889199 0,04822593 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01889199 0,04817247 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01889199 0,04811912 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01889199 0,04806589 ! protein targeting to ER GO:0045047 19 9 0,000 0,01889199 0,04801278 ! T cell selection GO:0045058 18 9 0,000 0,01889199 0,04795979 ! endoderm development GO:0007492 12 9 0,000 0,01889199 0,04790691 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01889199 0,04785415 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01889199 0,0478015 ! arginine catabolic process GO:0006527 10 9 0,000 0,01889199 0,04774897 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01889199 0,04769656 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01889199 0,04764426 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01889199 0,04759208 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01889199 0,04754001 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01889199 0,04748805 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01889199 0,04743621 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01889199 0,04738448 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01889199 0,04733286 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01889199 0,04728136 ! mannose metabolic process GO:0006013 9 9 0,000 0,01889199 0,04722996 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01889199 0,04717868 ! receptor clustering GO:0043113 15 9 0,000 0,01889199 0,04712751 ! epithelial cell development GO:0002064 10 9 0,000 0,01889199 0,04707645 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01889199 0,0470255 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01889199 0,04697467 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01889199 0,04692394 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01889199 0,04687332 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01889199 0,04682281 ! motor axon guidance GO:0008045 14 9 0,000 0,01889199 0,04677241 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01889199 0,04672211 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01889199 0,04667193 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01889199 0,04662185 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01889199 0,04657188 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01889199 0,04652202 ! DNA ligation GO:0006266 14 9 0,000 0,01889199 0,04647226 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01889199 0,04642261 ! response to amine stimulus GO:0014075 13 9 0,000 0,01889199 0,04637307 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01889199 0,04632363 ! erythrocyte development GO:0048821 11 9 0,000 0,01889199 0,0462743 ! renal water homeostasis GO:0003091 14 9 0,000 0,01889199 0,04622507 ! postreplication repair GO:0006301 11 9 0,000 0,01889199 0,04617595 ! mRNA cleavage GO:0006379 13 9 0,000 0,01889199 0,04612693 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01889199 0,04607801 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01889199 0,0460292 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01889199 0,04598049 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01889199 0,04593189 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01889199 0,04588339 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01889199 0,04583499 ! acid secretion GO:0046717 14 9 0,000 0,01889199 0,04578669 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01889199 0,04573849 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01889199 0,0456904 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01889199 0,0456424 ! purine base metabolic process GO:0006144 18 9 0,000 0,01889199 0,04559451 ! oocyte differentiation GO:0009994 12 9 0,000 0,01889199 0,04554671 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01889199 0,04549902 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01889199 0,04545143 ! spleen development GO:0048536 15 9 0,000 0,01889199 0,04540394 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01889199 0,04535654 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01889199 0,04530925 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01889199 0,04526205 ! detection of calcium ion GO:0005513 13 9 0,000 0,01889199 0,04521495 ! blastocyst formation GO:0001825 12 9 0,000 0,01889199 0,04516795 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01889199 0,04512104 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01889199 0,04507424 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01889199 0,04502753 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01889199 0,04498092 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01889199 0,0449344 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01889199 0,04488798 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01889199 0,04484166 ! prepulse inhibition GO:0060134 14 9 0,000 0,01889199 0,04479543 ! embryonic placenta development GO:0001892 12 9 0,000 0,01889199 0,0447493 ! insulin secretion GO:0030073 17 9 0,000 0,01889199 0,04470326 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01889199 0,04465731 ! response to nicotine GO:0035094 16 9 0,000 0,01889199 0,04461146 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01889199 0,04456571 ! nucleus localization GO:0051647 15 9 0,000 0,01889199 0,04452005 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01889199 0,04447448 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,01894308 0,04454917 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 1,000 0,01894308 0,04450367 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02096953 0,04921421 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02096953 0,04916404 ! neuron fate specification GO:0048665 11 10 0,000 0,02096953 0,04911398 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02096953 0,04906401 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02096953 0,04901415 ! thyroid gland development GO:0030878 19 10 0,000 0,02096953 0,04896439 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02096953 0,04891473 ! synapsis GO:0007129 13 10 0,000 0,02096953 0,04886517 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02096953 0,04881572 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02096953 0,04876636 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02096953 0,0487171 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02096953 0,04866794 ! sulfate transport GO:0008272 12 10 0,000 0,02096953 0,04861888 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02096953 0,04856992 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02096953 0,04852105 ! androgen metabolic process GO:0008209 13 10 0,000 0,02096953 0,04847229 ! phospholipid efflux GO:0033700 16 10 0,000 0,02096953 0,04842362 ! hippocampus development GO:0021766 19 10 0,000 0,02096953 0,04837505 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02096953 0,04832658 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02096953 0,0482782 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02096953 0,04822993 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02096953 0,04818174 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02096953 0,04813366 ! pathogenesis GO:0009405 13 10 0,000 0,02096953 0,04808567 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02096953 0,04803778 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02096953 0,04798998 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02096953 0,04794227 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02096953 0,04789466 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02096953 0,04784715 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02096953 0,04779973 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02096953 0,0477524 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02096953 0,04770517 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02096953 0,04765803 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02096953 0,04761098 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02096953 0,04756403 ! response to X-ray GO:0010165 16 10 0,000 0,02096953 0,04751717 ! B cell proliferation GO:0042100 14 10 0,000 0,02096953 0,0474704 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02096953 0,04742372 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02096953 0,04737714 ! forebrain cell migration GO:0021885 17 10 0,000 0,02096953 0,04733064 ! lipid digestion GO:0044241 15 10 0,000 0,02096953 0,04728424 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02096953 0,04723793 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02096953 0,04719171 ! UV protection GO:0009650 14 10 0,000 0,02096953 0,04714558 ! entry into host cell GO:0030260 20 10 0,000 0,02096953 0,04709954 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02096953 0,04705359 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02096953 0,04700773 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02096953 0,04696195 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02096953 0,04691627 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02096953 0,04687068 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02096953 0,04682517 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02096953 0,04677975 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02096953 0,04673442 ! regulation of organ growth GO:0046620 11 10 0,000 0,02096953 0,04668918 ! response to dsRNA GO:0043331 18 10 0,000 0,02096953 0,04664403 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02096953 0,04659896 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02096953 0,04655398 ! embryonic axis specification GO:0000578 12 10 0,000 0,02096953 0,04650909 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02096953 0,04646428 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02096953 0,04641956 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02096953 0,04637493 ! cranial nerve development GO:0021545 12 10 0,000 0,02096953 0,04633038 ! fucose catabolic process GO:0019317 16 10 0,000 0,02096953 0,04628592 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02096953 0,04624154 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02096953 0,04619725 ! protein sumoylation GO:0016925 12 10 0,000 0,02096953 0,04615304 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02096953 0,04610892 ! zymogen activation GO:0031638 14 10 0,000 0,02096953 0,04606488 ! salivary gland development GO:0007431 22 10 0,000 0,02096953 0,04602092 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02096953 0,04597705 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02096953 0,04593326 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02096953 0,04588956 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02096953 0,04584594 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02096953 0,0458024 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02096953 0,04575894 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02096953 0,04571557 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02096953 0,04567228 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02096953 0,04562907 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02096953 0,04558594 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02096953 0,0455429 ! detection of bacterium GO:0016045 10 10 0,000 0,02096953 0,04549993 ! embryonic gut development GO:0048566 11 10 0,000 0,02096953 0,04545705 ! activation of innate immune response GO:0002218 10 10 0,000 0,02096953 0,04541424 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02096953 0,04537152 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02096953 0,04532888 ! developmental induction GO:0031128 13 10 0,000 0,02096953 0,04528632 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02096953 0,04524383 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02096953 0,04520143 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02096953 0,04515911 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02096953 0,04511686 ! rRNA transcription GO:0009303 17 11 0,000 0,0230428 0,04953125 ! respiratory burst GO:0045730 14 11 0,000 0,0230428 0,04948501 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,0230428 0,04943884 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,0230428 0,04939277 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,0230428 0,04934678 ! virus-host interaction GO:0019048 17 11 0,000 0,0230428 0,04930088 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,0230428 0,04925506 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,0230428 0,04920932 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,0230428 0,04916367 ! RNA polyadenylation GO:0043631 19 11 0,000 0,0230428 0,04911811 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,0230428 0,04907263 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,0230428 0,04902724 ! mating GO:0007618 14 11 0,000 0,0230428 0,04898192 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,0230428 0,0489367 ! T cell proliferation GO:0042098 20 11 0,000 0,0230428 0,04889155 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,0230428 0,04884649 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,0230428 0,04880151 ! bone resorption GO:0045453 16 11 0,000 0,0230428 0,04875662 ! regulated secretory pathway GO:0045055 14 11 0,000 0,0230428 0,0487118 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,0230428 0,04866707 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,0230428 0,04862242 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,0230428 0,04857786 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,0230428 0,04853337 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,0230428 0,04848897 ! syncytium formation GO:0006949 15 11 0,000 0,0230428 0,04844464 ! plasma membrane organization GO:0007009 18 11 0,000 0,0230428 0,0484004 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,0230428 0,04835624 ! focal adhesion formation GO:0048041 24 11 0,000 0,0230428 0,04831216 ! mitotic spindle organization GO:0007052 15 11 0,000 0,0230428 0,04826816 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,0230428 0,04822424 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,0230428 0,0481804 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,0230428 0,04813664 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,0230428 0,04809296 ! adult heart development GO:0007512 11 11 0,000 0,0230428 0,04804936 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,0230428 0,04800583 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,0230428 0,04796239 ! temperature homeostasis GO:0001659 16 11 0,000 0,0230428 0,04791902 ! L-glutamate transport GO:0015813 16 11 0,000 0,0230428 0,04787574 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,0230428 0,04783253 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,0230428 0,0477894 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,0230428 0,04774634 ! stem cell development GO:0048864 29 11 0,000 0,0230428 0,04770337 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,0230428 0,04766047 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,0230428 0,04761765 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,0230428 0,0475749 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,0230428 0,04753223 ! vasoconstriction GO:0042310 15 11 0,000 0,0230428 0,04748964 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,0230428 0,04744713 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,0230428 0,04740469 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,0230428 0,04736232 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,0230428 0,04732004 ! ribosome assembly GO:0042255 13 11 0,000 0,0230428 0,04727782 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,0230428 0,04723569 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,0230428 0,04719363 ! chromatin silencing GO:0006342 19 11 0,000 0,0230428 0,04715164 ! nucleosome positioning GO:0016584 13 11 0,000 0,0230428 0,04710973 ! T cell homeostasis GO:0043029 20 11 0,000 0,0230428 0,04706789 ! regulation of isotype switching GO:0045191 19 11 0,000 0,0230428 0,04702612 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,0230428 0,04698443 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,0230428 0,04694282 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,0230428 0,04690128 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,0230428 0,04685981 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,0230428 0,04681841 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,0230428 0,04677709 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,0230428 0,04673584 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,0230428 0,04669466 ! male genitalia development GO:0030539 13 11 0,000 0,0230428 0,04665356 ! cholesterol efflux GO:0033344 19 11 0,000 0,0230428 0,04661253 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,0230428 0,04657157 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,0230428 0,04653068 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,0230428 0,04648986 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,0230428 0,04644912 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,0230428 0,04640844 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,0230428 0,04636784 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,0230428 0,04632731 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,0230428 0,04628685 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,0230428 0,04624646 ! lysogeny GO:0030069 18 11 0,000 0,0230428 0,04620614 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,0230428 0,04616589 ! acrosome reaction GO:0007340 13 11 0,000 0,0230428 0,04612571 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,0230428 0,0460856 ! lactation GO:0007595 20 12 0,000 0,0251118 0,05017996 ! reproductive cellular process GO:0048610 14 12 0,000 0,0251118 0,0501364 ! tRNA modification GO:0006400 14 12 0,000 0,0251118 0,05009291 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,0251118 0,05004951 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,0251118 0,05000617 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,0251118 0,04996292 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,0251118 0,04991973 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,0251118 0,04987662 ! non-recombinational repair GO:0000726 19 12 0,000 0,0251118 0,04983359 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,0251118 0,04979063 ! peroxisomal transport GO:0043574 21 12 0,000 0,0251118 0,04974774 ! cartilage condensation GO:0001502 18 12 0,000 0,0251118 0,04970493 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,0251118 0,04966219 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,0251118 0,04961953 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0251118 0,04957694 ! heart looping GO:0001947 15 12 0,000 0,0251118 0,04953442 ! palate development GO:0060021 15 12 0,000 0,0251118 0,04949197 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,0251118 0,0494496 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,0251118 0,0494073 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,0251118 0,04936507 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0251118 0,04932291 ! arginine metabolic process GO:0006525 13 12 0,000 0,0251118 0,04928083 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,0251118 0,04923882 ! methionine metabolic process GO:0006555 13 12 0,000 0,0251118 0,04919687 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,0251118 0,049155 ! Golgi organization GO:0007030 18 12 0,000 0,0251118 0,04911321 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,0251118 0,04907148 ! monoamine transport GO:0015844 13 12 0,000 0,0251118 0,04902982 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0251118 0,04898824 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,0251118 0,04894672 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,0251118 0,04890528 ! L-amino acid transport GO:0015807 20 12 0,000 0,0251118 0,0488639 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,0251118 0,0488226 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0251118 0,04878136 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,0251118 0,04874019 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0251118 0,0486991 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,0251118 0,04865807 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,0251118 0,04861711 ! cerebellum development GO:0021549 13 12 0,000 0,0251118 0,04857622 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0251118 0,0485354 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,0251118 0,04849465 ! histone acetylation GO:0016573 23 12 0,000 0,0251118 0,04845397 ! histone methylation GO:0016571 15 12 0,000 0,0251118 0,04841335 ! autonomic nervous system development GO:0048483 23 12 0,000 0,0251118 0,04837281 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,0251118 0,04833233 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,0251118 0,04829192 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,0251118 0,04825157 ! response to gamma radiation GO:0010332 20 12 0,000 0,0251118 0,04821129 ! regulation of epidermis development GO:0045682 17 12 0,000 0,0251118 0,04817108 ! intestinal absorption GO:0050892 19 12 0,000 0,0251118 0,04813094 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,0251118 0,04809087 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0251118 0,04805086 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,0251118 0,04801091 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,0251118 0,04797104 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,0251118 0,04793123 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,0251118 0,04789148 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,0251118 0,04785181 ! microspike assembly GO:0030035 23 12 0,000 0,0251118 0,04781219 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,0251118 0,04777265 ! response to cold GO:0009409 14 12 0,000 0,0251118 0,04773317 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02717653 0,05161521 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02717653 0,05157262 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02717653 0,0515301 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02717653 0,05148766 ! water transport GO:0006833 17 13 0,000 0,02717653 0,05144528 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02717653 0,05140297 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02717653 0,05136073 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02717653 0,05131857 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02717653 0,05127647 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02717653 0,05123444 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02717653 0,05119248 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02717653 0,05115058 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02717653 0,05110876 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02717653 0,051067 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02717653 0,05102532 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02717653 0,0509837 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02717653 0,05094215 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02717653 0,05090066 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02717653 0,05085925 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02717653 0,0508179 ! NAD metabolic process GO:0019674 21 13 0,000 0,02717653 0,05077662 ! exocrine system development GO:0035272 27 13 0,000 0,02717653 0,0507354 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02717653 0,05069425 ! bone mineralization GO:0030282 15 13 0,000 0,02717653 0,05065317 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02717653 0,05061216 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02717653 0,05057121 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02717653 0,05053033 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02717653 0,05048951 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02717653 0,05044876 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02717653 0,05040808 ! genitalia development GO:0048806 15 13 0,000 0,02717653 0,05036746 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02717653 0,0503269 ! cellular pigmentation GO:0033059 24 13 0,000 0,02717653 0,05028641 ! tissue regeneration GO:0042246 21 13 0,000 0,02717653 0,05024599 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02717653 0,05020563 ! cofactor transport GO:0051181 19 13 0,000 0,02717653 0,05016534 ! NADP metabolic process GO:0006739 18 13 0,000 0,02717653 0,05012511 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02717653 0,05008495 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02717653 0,05004485 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02717653 0,05000481 ! gas transport GO:0015669 18 13 0,000 0,02717653 0,04996484 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02717653 0,04992493 ! regulation of axon extension GO:0030516 23 13 0,000 0,02717653 0,04988509 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02717653 0,04984531 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02717653 0,04980559 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02717653 0,04976593 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02717653 0,04972634 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02717653 0,04968682 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02717653 0,04964735 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,029237 0,05336913 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,029237 0,05332681 ! superoxide anion generation GO:0042554 18 14 0,000 0,029237 0,05328456 ! neuron maturation GO:0042551 21 14 0,000 0,029237 0,05324237 ! regulation of S phase GO:0033261 18 14 0,000 0,029237 0,05320025 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,029237 0,05315819 ! myotube differentiation GO:0014902 21 14 0,000 0,029237 0,0531162 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,029237 0,05307428 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,029237 0,05303242 ! inositol metabolic process GO:0006020 20 14 0,000 0,029237 0,05299063 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,029237 0,05294891 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,029237 0,05290725 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,029237 0,05286565 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,029237 0,05282412 ! gene silencing by RNA GO:0031047 20 14 0,000 0,029237 0,05278266 ! response to cAMP GO:0051591 19 14 0,000 0,029237 0,05274126 ! limbic system development GO:0021761 25 14 0,000 0,029237 0,05269993 ! startle response GO:0001964 21 14 0,000 0,029237 0,05265866 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,029237 0,05261746 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,029237 0,05257632 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,029237 0,05253524 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,029237 0,05249423 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,029237 0,05245328 ! glycine metabolic process GO:0006544 22 14 0,000 0,029237 0,0524124 ! pituitary gland development GO:0021983 23 14 0,000 0,029237 0,05237158 ! cellular response to starvation GO:0009267 21 14 0,000 0,029237 0,05233082 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,029237 0,05229013 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,029237 0,0522495 ! regulation of heart rate GO:0002027 23 14 0,000 0,029237 0,05220894 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,029237 0,05216843 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,029237 0,05212799 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,029237 0,05208761 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,029237 0,0520473 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,029237 0,05200705 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,029237 0,05196685 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,029237 0,05192673 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,029237 0,05188666 ! axon cargo transport GO:0008088 27 14 0,000 0,029237 0,05184665 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,029237 0,05180671 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,029237 0,05176683 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,029237 0,05172701 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,029237 0,05168725 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,029237 0,05164755 ! mRNA splice site selection GO:0006376 26 14 0,000 0,029237 0,05160791 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,029237 0,05156834 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,029237 0,05152882 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,029237 0,05148936 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,029237 0,05144997 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,029237 0,05141063 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,029237 0,05137136 ! muscle maintenance GO:0046716 19 14 0,000 0,029237 0,05133215 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,029237 0,05129299 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,029237 0,05125389 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,029237 0,05121486 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,029237 0,05117588 ! cell killing GO:0001906 20 14 0,000 0,029237 0,05113697 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,029237 0,05109811 ! cilium assembly GO:0042384 20 14 0,000 0,029237 0,05105931 ! peptide hormone secretion GO:0030072 23 14 0,000 0,029237 0,05102057 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,03129323 0,05456743 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03129323 0,05452609 ! metencephalon development GO:0022037 19 15 0,000 0,03129323 0,05448481 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03129323 0,0544436 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,03129323 0,05440245 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03129323 0,05436136 ! skin development GO:0043588 25 15 0,000 0,03129323 0,05432033 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,03129323 0,05427937 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03129323 0,05423846 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03129323 0,05419762 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03129323 0,05415684 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03129323 0,05411612 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03129323 0,05407546 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,03129323 0,05403486 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03129323 0,05399433 ! adult walking behavior GO:0007628 25 15 0,000 0,03129323 0,05395385 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03129323 0,05391344 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03129323 0,05387308 ! centrosome cycle GO:0007098 16 15 0,000 0,03129323 0,05383279 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,03129323 0,05379256 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,03129323 0,05375238 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03129323 0,05371227 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03129323 0,05367221 ! cerebral cortex development GO:0021987 29 15 0,000 0,03129323 0,05363222 ! response to osmotic stress GO:0006970 22 15 0,000 0,03129323 0,05359229 ! vesicle coating GO:0006901 25 15 0,000 0,03129323 0,05355241 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03129323 0,05351259 ! DNA integration GO:0015074 22 15 0,000 0,03129323 0,05347284 ! peptide secretion GO:0002790 27 15 0,000 0,03129323 0,05343314 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,03129323 0,0533935 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,03129323 0,05335392 ! neuron recognition GO:0008038 22 15 0,000 0,03129323 0,0533144 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03129323 0,05327494 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03129323 0,05323553 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,03129323 0,05319619 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03129323 0,0531569 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03129323 0,05311767 ! biomineral formation GO:0031214 18 15 0,000 0,03129323 0,0530785 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03129323 0,05303938 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03129323 0,05300032 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03129323 0,05296132 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03129323 0,05292238 ! organic cation transport GO:0015695 19 15 0,000 0,03129323 0,0528835 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03129323 0,05284467 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,03129323 0,0528059 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03129323 0,05276718 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03129323 0,05272853 ! defense response to virus GO:0051607 27 15 0,000 0,03129323 0,05268993 ! peptide hormone processing GO:0016486 19 15 0,000 0,03129323 0,05265138 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,03129323 0,05261289 ! protein secretion GO:0009306 27 16 0,000 0,03334523 0,05602193 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03334523 0,05598104 ! hormone secretion GO:0046879 25 16 0,000 0,03334523 0,05594021 ! bone remodeling GO:0046849 24 16 0,000 0,03334523 0,05589943 ! endothelial cell migration GO:0043542 22 16 0,000 0,03334523 0,05585872 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03334523 0,05581807 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,03334523 0,05577747 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03334523 0,05573693 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03334523 0,05569646 ! glial cell development GO:0021782 24 16 0,000 0,03334523 0,05565604 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03334523 0,05561568 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03334523 0,05557538 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03334523 0,05553514 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03334523 0,05549495 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03334523 0,05545482 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,03334523 0,05541476 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03334523 0,05537475 ! fructose metabolic process GO:0006000 20 16 0,000 0,03334523 0,05533479 ! regulation of protein binding GO:0043393 27 16 0,000 0,03334523 0,0552949 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,03334523 0,05525506 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03334523 0,05521528 ! protein export from nucleus GO:0006611 24 16 0,000 0,03334523 0,05517556 ! negative regulation of immune response GO:0050777 28 16 0,000 0,03334523 0,05513589 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03334523 0,05509628 ! DNA replication initiation GO:0006270 25 16 0,000 0,03334523 0,05505673 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03334523 0,05501723 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03334523 0,05497779 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03334523 0,05493841 ! diencephalon development GO:0021536 25 16 0,000 0,03334523 0,05489909 ! oogenesis GO:0048477 23 16 0,000 0,03334523 0,05485982 ! neural crest cell migration GO:0001755 24 16 0,000 0,03334523 0,0548206 ! G1 phase GO:0051318 27 16 0,000 0,03334523 0,05478144 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03334523 0,05474234 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03334523 0,0547033 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03334523 0,05466431 ! steroid catabolic process GO:0006706 22 16 0,000 0,03334523 0,05462537 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03334523 0,05458649 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,03334523 0,05454767 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03334523 0,0545089 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03334523 0,05447019 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03334523 0,05443153 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03334523 0,05439292 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03334523 0,05435437 ! nerve development GO:0021675 18 16 0,000 0,03334523 0,05431588 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,03334523 0,05427744 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,03334523 0,05423905 ! negative regulation of translation GO:0017148 22 16 0,000 0,03334523 0,05420072 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03539299 0,05748861 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03539299 0,05744804 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03539299 0,05740753 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03539299 0,05736707 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03539299 0,05732667 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03539299 0,05728633 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03539299 0,05724605 ! signal complex assembly GO:0007172 29 17 0,000 0,03539299 0,05720582 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03539299 0,05716564 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03539299 0,05712553 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03539299 0,05708547 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03539299 0,05704546 ! memory GO:0007613 25 17 0,000 0,03539299 0,05700552 ! keratinization GO:0031424 17 17 0,000 0,03539299 0,05696562 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03539299 0,05692579 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,03539299 0,05688601 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03539299 0,05684628 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03539299 0,05680661 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03539299 0,056767 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03539299 0,05672744 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03539299 0,05668794 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03539299 0,05664849 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03539299 0,05660909 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03539299 0,05656975 ! membrane budding GO:0006900 29 17 0,000 0,03539299 0,05653047 ! heme metabolic process GO:0042168 27 17 0,000 0,03539299 0,05649124 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03539299 0,05645206 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03539299 0,05641294 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03539299 0,05637388 ! body fluid secretion GO:0007589 27 17 0,000 0,03539299 0,05633486 ! stem cell differentiation GO:0048863 36 17 0,000 0,03539299 0,0562959 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03539299 0,056257 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03539299 0,05621815 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03539299 0,05617935 ! sensory perception of pain GO:0019233 23 17 0,000 0,03539299 0,0561406 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03539299 0,05610191 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03539299 0,05606328 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03539299 0,05602469 ! synaptogenesis GO:0007416 24 17 0,000 0,03539299 0,05598616 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03539299 0,05594768 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03539299 0,05590926 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03539299 0,05587088 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03539299 0,05583256 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03539299 0,0557943 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03539299 0,05575608 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03539299 0,05571792 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03539299 0,05567981 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03743653 0,05885442 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03743653 0,05881422 ! positive regulation of translation GO:0045727 28 18 0,000 0,03743653 0,05877408 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03743653 0,05873399 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03743653 0,05869395 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03743653 0,05865397 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03743653 0,05861404 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03743653 0,05857417 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03743653 0,05853435 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03743653 0,05849458 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03743653 0,05845487 ! axis specification GO:0009798 26 18 0,000 0,03743653 0,05841521 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03743653 0,05837561 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03743653 0,05833606 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,03743653 0,05829656 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03743653 0,05825712 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03743653 0,05821773 ! response to retinoic acid GO:0032526 25 18 0,000 0,03743653 0,05817839 ! pigmentation during development GO:0048066 31 18 0,000 0,03743653 0,05813911 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03743653 0,05809988 ! fucose metabolic process GO:0006004 26 18 0,000 0,03743653 0,0580607 ! response to fungus GO:0009620 19 18 0,000 0,03743653 0,05802158 ! peptide cross-linking GO:0018149 31 18 0,000 0,03743653 0,05798251 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03743653 0,05794349 ! heart process GO:0003015 27 18 0,000 0,03743653 0,05790452 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03743653 0,05786561 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03743653 0,05782674 ! visual learning GO:0008542 35 18 0,000 0,03743653 0,05778794 ! somitogenesis GO:0001756 24 18 0,000 0,03743653 0,05774918 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03743653 0,05771047 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03743653 0,05767182 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03743653 0,05763321 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03743653 0,05759466 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03743653 0,05755617 ! vitamin transport GO:0051180 24 18 0,000 0,03743653 0,05751772 ! hormone transport GO:0009914 27 18 0,000 0,03743653 0,05747932 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03743653 0,05744098 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03743653 0,05740268 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03743653 0,05736444 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03743653 0,05732625 ! cell-cell recognition GO:0009988 20 18 0,000 0,03743653 0,05728811 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03743653 0,05725002 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03743653 0,05721198 ! regulation of glucose import GO:0046324 21 18 0,000 0,03743653 0,05717399 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03743653 0,05713605 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03743653 0,05709816 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03743653 0,05706032 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03743653 0,05702253 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03947586 0,060089 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03947586 0,06004926 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03947586 0,06000957 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03947586 0,05996993 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03947586 0,05993035 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03947586 0,05989082 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03947586 0,05985134 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03947586 0,05981191 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03947586 0,05977254 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03947586 0,05973321 ! regeneration GO:0031099 32 19 0,000 0,03947586 0,05969394 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03947586 0,05965472 ! response to alkaloid GO:0043279 32 19 0,000 0,03947586 0,05961555 ! sensory perception of taste GO:0050909 23 19 0,000 0,03947586 0,05957643 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03947586 0,05953736 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03947586 0,05949835 ! peroxisome organization GO:0007031 29 19 0,000 0,03947586 0,05945938 ! digestive system process GO:0022600 30 19 0,000 0,03947586 0,05942047 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03947586 0,05938161 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03947586 0,0593428 ! response to vitamin A GO:0033189 26 19 0,000 0,03947586 0,05930404 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03947586 0,05926533 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03947586 0,05922667 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03947586 0,05918806 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03947586 0,0591495 ! response to starvation GO:0042594 30 19 0,000 0,03947586 0,05911099 ! sex determination GO:0007530 29 19 0,000 0,03947586 0,05907253 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03947586 0,05903412 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03947586 0,05899576 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03947586 0,05895746 ! cytolysis GO:0019835 20 19 0,000 0,03947586 0,0589192 ! renal system process GO:0003014 35 19 0,000 0,03947586 0,05888099 ! vasodilation GO:0042311 33 19 0,000 0,03947586 0,05884283 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03947586 0,05880472 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03947586 0,05876665 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03947586 0,05872864 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03947586 0,05869068 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03947586 0,05865277 ! sarcomere organization GO:0045214 23 19 0,000 0,03947586 0,0586149 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03947586 0,05857708 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03947586 0,05853932 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03947586 0,0585016 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03947586 0,05846393 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03947586 0,05842631 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03947586 0,05838873 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03947586 0,05835121 ! protein stabilization GO:0050821 26 19 0,000 0,03947586 0,05831373 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,04151099 0,06128066 ! iron ion transport GO:0006826 37 20 0,000 0,04151099 0,06124135 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,04151099 0,0612021 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,04151099 0,06116289 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,04151099 0,06112373 ! response to vitamin GO:0033273 29 20 0,000 0,04151099 0,06108463 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,04151099 0,06104557 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,04151099 0,06100656 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,04151099 0,0609676 ! spinal cord development GO:0021510 31 20 0,000 0,04151099 0,0609287 ! response to ethanol GO:0045471 37 20 0,000 0,04151099 0,06088984 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,04151099 0,06085103 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,04151099 0,06081227 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,04151099 0,06077356 ! chromosome condensation GO:0030261 31 20 0,000 0,04151099 0,0607349 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,04151099 0,06069629 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,04151099 0,06065773 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,04151099 0,06061922 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,04151099 0,06058075 ! pallium development GO:0021543 38 20 0,000 0,04151099 0,06054234 ! DNA modification GO:0006304 28 20 0,000 0,04151099 0,06050397 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,04151099 0,06046565 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,04151099 0,06042739 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,04151099 0,06038916 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,04151099 0,06035099 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,04151099 0,06031287 ! collagen catabolic process GO:0030574 25 20 0,000 0,04151099 0,06027479 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,04151099 0,06023676 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,04151099 0,06019878 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,04151099 0,06016085 ! alditol metabolic process GO:0019400 24 20 0,000 0,04151099 0,06012297 ! actin filament-based movement GO:0030048 34 20 0,000 0,04151099 0,06008513 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04354192 0,06298516 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04354192 0,06294557 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04354192 0,06290603 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04354192 0,06286655 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04354192 0,06282711 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04354192 0,06278772 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04354192 0,06274838 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04354192 0,06270908 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04354192 0,06266984 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04354192 0,06263065 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04354192 0,0625915 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04354192 0,06255241 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04354192 0,06251336 ! phototransduction GO:0007602 25 21 0,000 0,04354192 0,06247437 ! dendrite development GO:0016358 35 21 0,000 0,04354192 0,06243542 ! visual behavior GO:0007632 39 21 0,000 0,04354192 0,06239652 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,04354192 0,06235766 ! ovarian follicle development GO:0001541 30 21 0,000 0,04354192 0,06231886 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04354192 0,0622801 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04354192 0,0622414 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04354192 0,06220274 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04354192 0,06216413 ! cell aging GO:0007569 32 21 0,000 0,04354192 0,06212556 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04354192 0,06208705 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04354192 0,06204858 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04354192 0,06201016 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04354192 0,06197179 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04354192 0,06193346 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04354192 0,06189518 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04354192 0,06185695 ! fatty acid transport GO:0015908 30 21 0,000 0,04354192 0,06181877 ! immunoglobulin production GO:0002377 33 21 0,000 0,04354192 0,06178063 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04354192 0,06174254 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,04354192 0,0617045 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04354192 0,06166651 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04354192 0,06162856 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04354192 0,06159066 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04354192 0,0615528 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04354192 0,06151499 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04354192 0,06147723 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04354192 0,06143951 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04354192 0,06140184 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04354192 0,06136422 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04354192 0,06132664 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04354192 0,06128911 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04354192 0,06125163 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,04556866 0,06406352 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04556866 0,06402438 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04556866 0,0639853 ! viral genome replication GO:0019079 29 22 0,000 0,04556866 0,06394626 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04556866 0,06390727 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,04556866 0,06386832 ! leukocyte adhesion GO:0007159 38 22 0,000 0,04556866 0,06382942 ! molting cycle process GO:0022404 40 22 0,000 0,04556866 0,06379057 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04556866 0,06375177 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04556866 0,06371302 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04556866 0,06367431 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04556866 0,06363565 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,04556866 0,06359704 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,04556866 0,06355847 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,04556866 0,06351995 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04556866 0,06348147 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,04556866 0,06344305 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,04556866 0,06340467 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,04556866 0,06336633 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04556866 0,06332805 ! regulation of behavior GO:0050795 38 22 0,000 0,04556866 0,0632898 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04556866 0,06325161 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04556866 0,06321346 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04556866 0,06317536 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04556866 0,0631373 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04556866 0,06309929 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04556866 0,06306132 ! blastocyst development GO:0001824 37 22 0,000 0,04556866 0,0630234 ! neural tube closure GO:0001843 33 22 0,000 0,04556866 0,06298553 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04556866 0,0629477 ! protein tetramerization GO:0051262 39 22 0,000 0,04556866 0,06290991 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04759122 0,06566275 ! neuron fate commitment GO:0048663 32 23 0,000 0,04759122 0,06562339 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04759122 0,06558407 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,04759122 0,0655448 ! myelination GO:0042552 35 23 0,000 0,04759122 0,06550557 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04759122 0,06546639 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04759122 0,06542726 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,04759122 0,06538818 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04759122 0,06534914 ! vesicle targeting GO:0006903 32 23 0,000 0,04759122 0,06531015 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04759122 0,06527121 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04759122 0,06523231 ! osteoblast differentiation GO:0001649 40 23 0,000 0,04759122 0,06519345 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04759122 0,06515465 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04759122 0,06511589 ! interaction with host GO:0051701 37 23 0,000 0,04759122 0,06507718 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04759122 0,06503851 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04759122 0,06499989 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04759122 0,06496131 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04759122 0,06492278 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04759122 0,0648843 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04759122 0,06484586 ! cell fate determination GO:0001709 45 23 0,000 0,04759122 0,06480747 ! pentose metabolic process GO:0019321 31 23 0,000 0,04759122 0,06476912 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04759122 0,06473082 ! spermatid development GO:0007286 33 23 0,000 0,04759122 0,06469256 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04759122 0,06465435 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04759122 0,06461618 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04759122 0,06457806 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04759122 0,06453998 ! telomere organization GO:0032200 32 23 0,000 0,04759122 0,06450195 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04759122 0,06446396 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04759122 0,06442602 ! regulation of amine transport GO:0051952 38 23 0,000 0,04759122 0,06438812 ! liver development GO:0001889 40 23 0,000 0,04759122 0,06435027 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04960962 0,06704002 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04960962 0,06700065 ! initiation of viral infection GO:0019059 42 24 0,000 0,04960962 0,06696134 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04960962 0,06692206 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04960962 0,06688283 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04960962 0,06684365 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04960962 0,06680452 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04960962 0,06676543 ! sperm motility GO:0030317 27 24 0,000 0,04960962 0,06672638 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04960962 0,06668738 ! vacuole organization GO:0007033 39 24 0,000 0,04960962 0,06664843 ! receptor metabolic process GO:0043112 37 24 0,000 0,04960962 0,06660952 ! neural crest cell development GO:0014032 39 24 0,000 0,04960962 0,06657066 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04960962 0,06653185 ! primary neural tube formation GO:0014020 35 24 0,000 0,04960962 0,06649307 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04960962 0,06645435 ! base-excision repair GO:0006284 31 24 0,000 0,04960962 0,06641567 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04960962 0,06637703 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04960962 0,06633844 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04960962 0,06629989 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04960962 0,06626139 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04960962 0,06622293 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04960962 0,06618452 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,05162385 0,06883179 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,05162385 0,06879192 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,05162385 0,06875208 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,05162385 0,0687123 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,05162385 0,06867255 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,05162385 0,06863286 ! peptide transport GO:0015833 43 25 0,000 0,05162385 0,06859321 ! male gonad development GO:0008584 33 25 0,000 0,05162385 0,06855361 ! iron ion homeostasis GO:0055072 39 25 0,000 0,05162385 0,06851405 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,05162385 0,06847454 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,05162385 0,06843507 ! phospholipid transport GO:0015914 35 25 0,000 0,05162385 0,06839565 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,05162385 0,06835627 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,05162385 0,06831694 ! detection of light stimulus GO:0009583 30 25 0,000 0,05162385 0,06827766 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,05162385 0,06823842 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,05162385 0,06819922 ! leukocyte proliferation GO:0070661 39 25 0,000 0,05162385 0,06816007 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,05162385 0,06812097 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,05363392 0,07073281 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,05363392 0,07069228 ! translational initiation GO:0006413 43 26 0,000 0,05363392 0,07065179 ! regulation of pH GO:0006885 36 26 0,000 0,05363392 0,07061135 ! circadian rhythm GO:0007623 42 26 0,000 0,05363392 0,07057095 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,05363392 0,0705306 ! post-embryonic development GO:0009791 42 26 0,000 0,05363392 0,0704903 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,05363392 0,07045004 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,05363392 0,07040983 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,05363392 0,07036967 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,05363392 0,07032955 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,05363392 0,07028947 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,05363392 0,07024944 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,05563986 0,07283533 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,05563986 0,07279389 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,05563986 0,07275251 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,05563986 0,07271117 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,05563986 0,07266988 ! catechol metabolic process GO:0009712 43 27 0,000 0,05563986 0,07262864 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,05563986 0,07258745 ! acute-phase response GO:0006953 42 27 0,000 0,05563986 0,0725463 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,05563986 0,07250519 ! myofibril assembly GO:0030239 36 27 0,000 0,05563986 0,07246414 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,05563986 0,07242313 ! response to ionizing radiation GO:0010212 47 27 0,000 0,05563986 0,07238216 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,05563986 0,07234125 ! natural killer cell activation GO:0030101 35 27 0,000 0,05563986 0,07230038 ! lipid oxidation GO:0034440 38 27 0,000 0,05563986 0,07225955 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,05563986 0,07221877 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,05563986 0,07217804 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,05563986 0,07213735 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,05563986 0,07209671 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,05563986 0,07205612 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,05563986 0,07201557 ! gene silencing GO:0016458 41 27 0,000 0,05563986 0,07197507 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05764165 0,07452265 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05764165 0,07448078 ! phenol metabolic process GO:0018958 44 28 0,000 0,05764165 0,07443896 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05764165 0,07439719 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05764165 0,07435547 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05764165 0,07431379 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05764165 0,07427215 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05764165 0,07423057 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,05764165 0,07418903 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05764165 0,07414754 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05764165 0,07410609 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05764165 0,07406469 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05764165 0,07402334 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05764165 0,07398203 ! mesoderm formation GO:0001707 46 28 0,000 0,05764165 0,07394077 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05764165 0,07389955 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05764165 0,07385838 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05764165 0,07381726 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05764165 0,07377618 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05764165 0,07373515 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05764165 0,07369416 ! neural tube formation GO:0001841 41 28 0,000 0,05764165 0,07365322 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05764165 0,07361232 ! placenta development GO:0001890 37 28 0,000 0,05764165 0,07357147 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05963932 0,07607899 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05963932 0,07603682 ! ovulation cycle process GO:0022602 41 29 0,000 0,05963932 0,0759947 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05963932 0,07595262 ! protein targeting to membrane GO:0006612 53 29 0,000 0,05963932 0,07591058 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05963932 0,0758686 ! mismatch repair GO:0006298 34 29 0,000 0,05963932 0,07582666 ! muscle cell development GO:0055001 38 29 0,000 0,05963932 0,07578477 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05963932 0,07574292 ! telencephalon development GO:0021537 52 29 0,000 0,05963932 0,07570112 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,05963932 0,07565936 ! eye morphogenesis GO:0048592 51 29 0,000 0,05963932 0,07561765 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05963932 0,07557599 ! tissue homeostasis GO:0001894 42 29 0,000 0,05963932 0,07553438 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,06163286 0,07801628 ! collagen metabolic process GO:0032963 40 30 0,000 0,06163286 0,07797337 ! organic anion transport GO:0015711 51 30 0,000 0,06163286 0,0779305 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,06163286 0,07788768 ! spliceosome assembly GO:0000245 49 30 0,000 0,06163286 0,07784491 ! spindle organization GO:0007051 37 30 0,000 0,06163286 0,07780218 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,06163286 0,07775951 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,06163286 0,07771687 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,06163286 0,07767429 ! ceramide metabolic process GO:0006672 43 30 0,000 0,06163286 0,07763175 ! ovulation cycle GO:0042698 43 30 0,000 0,06163286 0,07758926 ! hindbrain development GO:0030902 45 30 0,000 0,06163286 0,07754682 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,06163286 0,07750442 ! adult locomotory behavior GO:0008344 47 30 0,000 0,06163286 0,07746207 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,06163286 0,07741976 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,06163286 0,0773775 ! response to heat GO:0009408 41 30 0,000 0,06163286 0,07733529 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,06163286 0,07729312 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,06163286 0,077251 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,06362229 0,07970113 ! negative regulation of secretion GO:0051048 49 31 0,000 0,06362229 0,07965774 ! glial cell differentiation GO:0010001 55 31 0,000 0,06362229 0,0796144 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,06362229 0,07957111 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,06362229 0,07952787 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,06362229 0,07948467 ! odontogenesis GO:0042476 50 31 0,000 0,06362229 0,07944152 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,06362229 0,07939841 ! segmentation GO:0035282 41 31 0,000 0,06362229 0,07935536 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,06362229 0,07931234 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,06362229 0,07926938 ! metanephros development GO:0001656 58 31 0,000 0,06362229 0,07922646 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,06362229 0,07918359 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,06362229 0,07914077 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,06362229 0,07909799 ! cell fate specification GO:0001708 37 31 0,000 0,06362229 0,07905525 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,06362229 0,07901257 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,06362229 0,07896993 ! RNA modification GO:0009451 40 31 0,000 0,06362229 0,07892733 ! regulation of muscle development GO:0048634 48 32 0,000 0,06560762 0,08134638 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,06560762 0,08130255 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,06560762 0,08125877 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,06560762 0,08121503 ! meiosis I GO:0007127 52 32 0,000 0,06560762 0,08117135 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,06560762 0,08112771 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,06560762 0,08108411 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,06560762 0,08104057 ! peripheral nervous system development GO:0007422 53 32 0,000 0,06560762 0,08099707 ! regulation of protein stability GO:0031647 48 32 0,000 0,06560762 0,08095361 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,06560762 0,0809102 ! cytokine production GO:0001816 44 32 0,000 0,06560762 0,08086684 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,06560762 0,08082353 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,06560762 0,08078026 ! vesicle localization GO:0051648 47 32 0,000 0,06560762 0,08073704 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,06758886 0,08313068 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,06758886 0,08308625 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,06758886 0,08304186 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06758886 0,08299753 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06758886 0,08295324 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,06758886 0,082909 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06758886 0,0828648 ! ear morphogenesis GO:0042471 42 33 0,000 0,06758886 0,08282065 ! actomyosin structure organization GO:0031032 43 33 0,000 0,06758886 0,08277655 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06758886 0,0827325 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06758886 0,08268849 ! nucleus organization GO:0006997 49 33 0,000 0,06758886 0,08264453 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,06758886 0,08260062 ! female gonad development GO:0008585 49 33 0,000 0,06758886 0,08255675 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06758886 0,08251293 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06758886 0,08246916 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,06758886 0,08242543 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06758886 0,08238175 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,06758886 0,08233812 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06758886 0,08229453 ! cytokinesis GO:0000910 52 33 0,000 0,06758886 0,08225099 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06758886 0,08220749 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,069566 0,08456755 ! mRNA catabolic process GO:0006402 48 34 0,000 0,069566 0,08452288 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,069566 0,08447825 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,069566 0,08443367 ! feeding behavior GO:0007631 45 34 0,000 0,069566 0,08438914 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,069566 0,08434465 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,069566 0,08430021 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,069566 0,08425582 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,069566 0,08421148 ! neuron migration GO:0001764 46 34 0,000 0,069566 0,08416718 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,069566 0,08412292 ! female gamete generation GO:0007292 43 34 0,000 0,069566 0,08407872 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,069566 0,08403456 ! polyol metabolic process GO:0019751 44 34 0,000 0,069566 0,08399045 ! aerobic respiration GO:0009060 47 34 0,000 0,069566 0,08394638 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,069566 0,08390236 ! embryonic organ development GO:0048568 45 34 0,000 0,069566 0,08385839 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,069566 0,08381446 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,07153907 0,08614652 ! Notch signaling pathway GO:0007219 56 35 0,000 0,07153907 0,08610144 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,07153907 0,08605641 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,07153907 0,08601142 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,07153907 0,08596649 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,07153907 0,0859216 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,07153907 0,08587675 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,07153907 0,08583195 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,07153907 0,0857872 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,07153907 0,0857425 ! pigment metabolic process GO:0042440 61 35 0,000 0,07153907 0,08569784 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,07350806 0,08801069 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,07350806 0,0879649 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,07350806 0,08791916 ! negative regulation of binding GO:0051100 58 36 0,000 0,07350806 0,08787346 ! neural tube development GO:0021915 50 36 0,000 0,07350806 0,08782781 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,07350806 0,08778221 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,07350806 0,08773666 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,07350806 0,08769115 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,07350806 0,08764569 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,07547299 0,08994191 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,07547299 0,08989533 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,07547299 0,0898488 ! learning GO:0007612 67 37 0,000 0,07547299 0,08980232 ! ion transmembrane transport GO:0034220 56 37 0,000 0,07547299 0,08975589 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,07547299 0,0897095 ! regulation of protein secretion GO:0050708 51 37 0,000 0,07547299 0,08966316 ! amino acid activation GO:0043038 52 37 0,000 0,07547299 0,08961688 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,07547299 0,08957063 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,07743387 0,09185039 ! gliogenesis GO:0042063 71 38 0,000 0,07743387 0,09180304 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,07743387 0,09175575 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,07743387 0,0917085 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,07743387 0,0916613 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,07743387 0,09161415 ! phagocytosis GO:0006909 60 38 0,000 0,07743387 0,09156705 ! pigmentation GO:0043473 74 38 0,000 0,07743387 0,09151999 ! maintenance of location in cell GO:0051651 69 38 0,000 0,07743387 0,09147299 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,0793907 0,09373645 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,0793907 0,09368836 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,0793907 0,09364031 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,0793907 0,09359232 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,0793907 0,09354437 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,0793907 0,09349647 ! male sex differentiation GO:0046661 53 39 0,000 0,0793907 0,09344863 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,0793907 0,09340083 ! chromatin remodeling GO:0006338 68 39 0,000 0,0793907 0,09335307 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,0793907 0,09330537 ! JNK cascade GO:0007254 54 39 0,000 0,0793907 0,09325772 ! developmental growth GO:0048589 62 39 0,000 0,0793907 0,09321011 ! cell growth GO:0016049 61 39 0,000 0,0793907 0,09316256 ! synapse organization GO:0050808 55 39 0,000 0,0793907 0,09311505 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,08134349 0,0953568 ! response to calcium ion GO:0051592 58 40 0,000 0,08134349 0,09530822 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,08134349 0,09525969 ! regulation of tube size GO:0035150 60 40 0,000 0,08134349 0,09521121 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,08134349 0,09516278 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,08134349 0,0951144 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,08134349 0,09506607 ! peptide metabolic process GO:0006518 56 40 0,000 0,08134349 0,09501779 ! inner ear development GO:0048839 57 40 0,000 0,08134349 0,09496956 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,08134349 0,09492138 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,08134349 0,09487324 ! double-strand break repair GO:0006302 67 40 0,000 0,08134349 0,09482516 ! B cell differentiation GO:0030183 62 40 0,000 0,08134349 0,09477712 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,08134349 0,09472913 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,08134349 0,09468119 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,08134349 0,0946333 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,08329225 0,09685146 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,08329225 0,09680252 ! glucose transport GO:0015758 52 41 0,000 0,08329225 0,09675363 ! endosome transport GO:0016197 71 41 0,000 0,08329225 0,09670479 ! striated muscle contraction GO:0006941 62 41 0,000 0,08329225 0,096656 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,08329225 0,09660725 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,08329225 0,09655856 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,08329225 0,09650992 ! biopolymer methylation GO:0043414 62 41 0,000 0,08329225 0,09646132 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,08329225 0,09641278 ! mitochondrial transport GO:0006839 60 42 0,000 0,08523699 0,09861423 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,08523699 0,09856465 ! cellular component disassembly GO:0022411 64 42 0,000 0,08523699 0,09851512 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,08523699 0,09846564 ! hexose transport GO:0008645 54 42 0,000 0,08523699 0,09841621 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,08523699 0,09836683 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,08523699 0,09831749 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,08523699 0,09826821 ! excretion GO:0007588 63 42 0,000 0,08523699 0,09821898 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,08523699 0,0981698 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,08523699 0,09812066 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,08523699 0,09807158 ! regulation of cell shape GO:0008360 78 42 0,000 0,08523699 0,09802254 ! positive regulation of binding GO:0051099 59 43 0,000 0,08717772 0,10020427 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,08717772 0,10015422 ! leukocyte migration GO:0050900 60 43 0,000 0,08717772 0,10010422 ! neuromuscular process GO:0050905 79 43 0,000 0,08717772 0,10005427 ! activation of caspase activity GO:0006919 65 43 0,000 0,08717772 0,10000436 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,08717772 0,09995451 ! tRNA processing GO:0008033 49 43 0,000 0,08717772 0,09990471 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,08717772 0,09985495 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,08717772 0,09980525 ! methylation GO:0032259 64 43 0,000 0,08717772 0,0997556 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,08911444 0,10192103 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,08911444 0,10187038 ! glycolysis GO:0006096 53 44 0,000 0,08911444 0,10181977 ! regulation of action potential GO:0001508 71 44 0,000 0,08911444 0,10176922 ! regulation of ion transport GO:0043269 57 44 0,000 0,08911444 0,10171871 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,08911444 0,10166825 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,08911444 0,10161785 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,08911444 0,10156749 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,08911444 0,10151719 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,08911444 0,10146693 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,08911444 0,10141672 ! RNA catabolic process GO:0006401 64 45 0,000 0,09104715 0,10356501 ! positive regulation of defense response GO:0031349 59 45 0,000 0,09104715 0,10351382 ! regulation of translational initiation GO:0006446 64 45 0,000 0,09104715 0,10346268 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,09104715 0,10341158 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,09104715 0,10336054 ! cell recognition GO:0008037 58 45 0,000 0,09104715 0,10330955 ! cell maturation GO:0048469 60 45 0,000 0,09104715 0,10325861 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,09297588 0,10539405 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,09297588 0,10534213 ! cell redox homeostasis GO:0045454 63 46 0,000 0,09297588 0,10529027 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,09297588 0,10523845 ! regulation of ossification GO:0030278 71 46 0,000 0,09297588 0,10518669 ! histone modification GO:0016570 68 46 0,000 0,09297588 0,10513497 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,09297588 0,10508331 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,09490063 0,10720602 ! viral infectious cycle GO:0019058 71 47 0,000 0,09490063 0,10715339 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,09490063 0,10710081 ! endocrine system development GO:0035270 83 47 0,000 0,09490063 0,10704828 ! covalent chromatin modification GO:0016569 75 47 0,000 0,09490063 0,10699581 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,09490063 0,10694339 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,09490063 0,10689101 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,09490063 0,10683869 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,09490063 0,10678642 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,09490063 0,10673421 ! chloride transport GO:0006821 67 48 0,000 0,0968214 0,10884127 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,0968214 0,10878809 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,0968214 0,10873498 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,0968214 0,10868191 ! gastrulation GO:0007369 73 48 0,000 0,0968214 0,10862889 ! heart morphogenesis GO:0003007 65 48 0,000 0,0968214 0,10857593 ! regulation of DNA replication GO:0006275 75 48 0,000 0,0968214 0,10852302 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,0968214 0,10847016 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,0968214 0,10841735 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,0968214 0,10836459 ! regulation of endocytosis GO:0030100 63 48 0,000 0,0968214 0,10831188 ! nuclear export GO:0051168 69 48 0,000 0,0968214 0,10825923 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,0968214 0,10820662 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,0968214 0,10815407 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,09873821 0,11024169 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,09873821 0,1101882 ! sensory perception of smell GO:0007608 61 49 0,000 0,09873821 0,11013477 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,09873821 0,11008138 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,09873821 0,11002805 ! RNA elongation GO:0006354 62 49 0,000 0,09873821 0,10997476 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,09873821 0,10992153 ! germ cell development GO:0007281 68 49 0,000 0,09873821 0,10986835 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,09873821 0,10981523 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,09873821 0,10976215 ! cartilage development GO:0051216 70 49 0,000 0,09873821 0,10970912 ! maintenance of location GO:0051235 84 49 0,000 0,09873821 0,10965615 ! regulation of actin filament length GO:0030832 72 50 0,000 0,10065106 0,11172656 ! ear development GO:0043583 72 50 0,000 0,10065106 0,11167267 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,10065106 0,11161882 ! positive regulation of growth GO:0045927 67 50 0,000 0,10065106 0,11156503 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,10065106 0,11151129 ! proton transport GO:0015992 75 50 0,000 0,10065106 0,1114576 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,10065106 0,11140396 ! hydrogen transport GO:0006818 77 51 0,000 0,10255996 0,11346219 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,10255996 0,11340765 ! adult behavior GO:0030534 80 51 0,000 0,10255996 0,11335315 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,10255996 0,1132987 ! transition metal ion transport GO:0000041 74 52 0,000 0,10446491 0,11534772 ! regulation of cellular component size GO:0032535 74 52 0,000 0,10446491 0,11529237 ! aging GO:0007568 79 52 0,000 0,10446491 0,11523707 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,10446491 0,11518183 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,10446491 0,11512664 ! establishment of organelle localization GO:0051656 85 52 0,000 0,10446491 0,1150715 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,10636593 0,11710945 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,10636593 0,11705342 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,10636593 0,11699744 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,10636593 0,11694151 ! kidney development GO:0001822 90 53 0,000 0,10636593 0,11688564 ! single fertilization GO:0007338 59 53 0,000 0,10636593 0,11682982 ! cell projection assembly GO:0030031 76 53 0,000 0,10636593 0,11677406 ! amino acid transport GO:0006865 84 54 0,000 0,10826303 0,11880008 ! regulation of mitosis GO:0007088 84 54 0,000 0,10826303 0,11874343 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,10826303 0,11868683 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,10826303 0,11863028 ! DNA catabolic process GO:0006308 67 54 0,000 0,10826303 0,11857379 ! detection of external stimulus GO:0009581 66 54 0,000 0,10826303 0,11851736 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,10826303 0,11846097 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,10826303 0,11840464 ! exocytosis GO:0006887 74 55 0,000 0,1101562 0,1204179 ! mesoderm development GO:0007498 76 55 0,000 0,1101562 0,1203607 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,1101562 0,12030355 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,1101562 0,12024645 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,11204547 0,12225075 ! carbohydrate transport GO:0008643 74 57 0,000 0,11393083 0,12424889 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,11393083 0,12419001 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,11393083 0,12413118 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,11393083 0,1240724 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,11393083 0,12401368 ! camera-type eye development GO:0043010 88 57 0,000 0,11393083 0,12395502 ! secondary metabolic process GO:0019748 84 57 0,000 0,11393083 0,12389641 ! developmental maturation GO:0021700 75 57 0,000 0,11393083 0,12383786 ! gonad development GO:0008406 79 57 0,000 0,11393083 0,12377936 ! viral reproductive process GO:0022415 87 58 0,000 0,1158123 0,12576406 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,1158123 0,12570471 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,1158123 0,12564542 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,11768988 0,12762222 ! activation of MAPK activity GO:0000187 84 59 0,000 0,11768988 0,12756207 ! lung development GO:0030324 94 59 0,000 0,11768988 0,12750199 ! actin filament organization GO:0007015 95 59 0,000 0,11768988 0,12744196 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,11768988 0,12738199 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,11768988 0,12732207 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,11956358 0,12928831 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,11956358 0,12922755 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,11956358 0,12916685 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,11956358 0,12910621 ! regulation of heart contraction GO:0008016 91 60 0,000 0,11956358 0,12904563 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,11956358 0,1289851 ! fertilization GO:0009566 68 60 0,000 0,11956358 0,12892463 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,11956358 0,12886421 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,12143341 0,13081819 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,12143341 0,13075694 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,12143341 0,13069576 ! urogenital system development GO:0001655 101 61 0,000 0,12143341 0,13063463 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,12143341 0,13057355 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,12143341 0,13051254 ! extracellular matrix organization GO:0030198 103 61 0,000 0,12143341 0,13045158 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,12143341 0,13039068 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,12143341 0,13032983 ! amine catabolic process GO:0009310 90 62 0,000 0,12329937 0,13227078 ! neurotransmitter transport GO:0006836 81 62 0,000 0,12329937 0,13220912 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,12329937 0,13214751 ! respiratory tube development GO:0030323 99 62 0,000 0,12329937 0,13208596 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,12329937 0,13202447 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,12329937 0,13196303 ! organelle localization GO:0051640 96 62 0,000 0,12329937 0,13190165 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,12516148 0,13383143 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,12516148 0,13376924 ! viral reproduction GO:0016032 92 63 0,000 0,12516148 0,13370711 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,12701974 0,13562925 ! appendage morphogenesis GO:0035107 93 64 0,000 0,12701974 0,13556631 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,12701974 0,13550343 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,12701974 0,13544061 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,12701974 0,13537785 ! hexose catabolic process GO:0019320 82 64 0,000 0,12701974 0,13531514 ! respiratory system development GO:0060541 100 64 0,000 0,12701974 0,1352525 ! adaptive immune response GO:0002250 94 64 0,000 0,12701974 0,13518991 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,12887416 0,13710017 ! appendage development GO:0048736 94 65 0,000 0,12887416 0,13703678 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,12887416 0,13697346 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,12887416 0,13691019 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,12887416 0,13684698 ! defense response to bacterium GO:0042742 73 65 0,000 0,12887416 0,13678383 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,12887416 0,13672074 ! activation of immune response GO:0002253 83 65 0,000 0,12887416 0,1366577 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,13072474 0,13855618 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,13072474 0,13849236 ! antigen processing and presentation GO:0019882 96 66 0,000 0,13072474 0,1384286 ! axon guidance GO:0007411 99 66 0,000 0,13072474 0,13836489 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,13072474 0,13830125 ! regulation of immune effector process GO:0002697 101 66 0,000 0,13072474 0,13823766 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,1325715 0,14012613 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,1325715 0,14006176 ! acute inflammatory response GO:0002526 92 68 0,000 0,13441445 0,14194363 ! learning or memory GO:0007611 123 68 0,000 0,13441445 0,14187849 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,13441445 0,14181341 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,13441445 0,14174839 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,13441445 0,14168342 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,13441445 0,14161852 ! rhythmic process GO:0048511 105 68 0,000 0,13441445 0,14155368 ! inorganic anion transport GO:0015698 93 68 0,000 0,13441445 0,14148889 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,13625358 0,14335921 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,13625358 0,14329366 ! response to drug GO:0042493 108 69 0,000 0,13625358 0,14322817 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,13625358 0,14316274 ! response to metal ion GO:0010038 103 70 0,000 0,13808891 0,14502488 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,13808891 0,14495869 ! humoral immune response GO:0006959 86 70 0,000 0,13808891 0,14489256 ! eye development GO:0001654 111 70 0,000 0,13808891 0,14482649 ! amine transport GO:0015837 101 70 0,000 0,13808891 0,14476048 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,13808891 0,14469453 ! regulation of catabolic process GO:0009894 106 70 0,000 0,13808891 0,14462864 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,13992045 0,14648021 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,13992045 0,14641357 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,13992045 0,14634699 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,13992045 0,14628047 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,13992045 0,14621401 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,13992045 0,14614761 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,1417482 0,14798949 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,1417482 0,14792235 ! negative regulation of transport GO:0051051 116 73 0,000 0,14357217 0,14975782 ! regulation of blood pressure GO:0008217 107 73 0,000 0,14357217 0,14968993 ! tube morphogenesis GO:0035239 118 73 0,000 0,14357217 0,1496221 ! mitochondrion organization GO:0007005 104 73 0,000 0,14357217 0,14955434 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,14357217 0,14948664 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,14357217 0,149419 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,14539236 0,15124488 ! digestion GO:0007586 97 74 0,000 0,14539236 0,15117651 ! protein import into nucleus GO:0006606 118 74 0,000 0,14539236 0,1511082 ! blood coagulation GO:0007596 116 75 0,000 0,1472088 0,15292694 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,1472088 0,15285789 ! response to nutrient GO:0007584 104 75 0,000 0,1472088 0,15278892 ! regulation of ligase activity GO:0051340 114 75 0,000 0,1472088 0,15272 ! nuclear import GO:0051170 121 75 0,000 0,1472088 0,15265114 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,1472088 0,15258235 ! amine biosynthetic process GO:0009309 97 76 0,000 0,14902148 0,15439162 ! tRNA metabolic process GO:0006399 95 76 0,000 0,14902148 0,1543221 ! response to unfolded protein GO:0006986 99 76 0,000 0,14902148 0,15425265 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,14902148 0,15418326 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,1508304 0,15598468 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,1508304 0,15591458 ! regulation of DNA binding GO:0051101 119 77 0,000 0,1508304 0,15584453 ! sex differentiation GO:0007548 105 77 0,000 0,1508304 0,15577455 ! protein ubiquitination GO:0016567 125 77 0,000 0,1508304 0,15570464 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,1508304 0,15563478 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,1508304 0,15556499 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,1508304 0,15549526 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,15263559 0,15728578 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,15263559 0,15721534 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,15263559 0,15714497 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,15443704 0,1589285 ! cellular respiration GO:0045333 107 79 0,000 0,15443704 0,15885742 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,15443704 0,15878641 ! T cell activation GO:0042110 134 79 0,000 0,15443704 0,15871546 ! regulation of lyase activity GO:0051339 133 79 0,000 0,15443704 0,15864457 ! chromatin assembly GO:0031497 102 80 0,000 0,15623477 0,16041963 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,15623477 0,16034805 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,15623477 0,16027653 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,15623477 0,16020507 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,15623477 0,16013368 ! forebrain development GO:0030900 131 80 0,000 0,15623477 0,16006235 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,15802878 0,16182822 ! hemostasis GO:0007599 125 81 0,000 0,15802878 0,1617562 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,15802878 0,16168425 ! response to protein stimulus GO:0051789 111 81 0,000 0,15802878 0,16161236 ! regulation of neurological system process GO:0031644 122 81 0,000 0,15802878 0,16154053 ! vitamin metabolic process GO:0006766 103 81 0,000 0,15802878 0,16146876 ! detection of stimulus GO:0051606 108 82 0,000 0,15981907 0,16322552 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,16160566 0,16497693 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,16160566 0,16490374 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,16160566 0,16483061 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,16338856 0,16657522 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,16338856 0,16650141 ! sterol metabolic process GO:0016125 120 84 0,000 0,16338856 0,16642767 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,16516777 0,1681655 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,16516777 0,16809109 ! rRNA metabolic process GO:0016072 107 85 0,000 0,16516777 0,16801675 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,16516777 0,16794247 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,16516777 0,16786825 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,16694329 0,16959786 ! nucleosome organization GO:0034728 114 87 0,000 0,16871514 0,17132222 ! cellular defense response GO:0006968 102 87 0,000 0,16871514 0,17124661 ! female pregnancy GO:0007565 130 87 0,000 0,16871514 0,17117107 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,17048332 0,17288873 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,17048332 0,17281253 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,17048332 0,17273641 ! reproductive developmental process GO:0003006 127 89 0,000 0,17224785 0,1744474 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,17224785 0,17437062 ! regulation of T cell activation GO:0050863 128 89 0,000 0,17224785 0,1742939 ! leukocyte differentiation GO:0002521 143 90 0,000 0,17400872 0,17599826 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,17400872 0,1759209 ! hormone metabolic process GO:0042445 121 90 0,000 0,17400872 0,17584361 ! response to virus GO:0009615 122 91 0,000 0,17576594 0,17754136 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,17751953 0,17923394 ! positive regulation of immune response GO:0050778 121 92 0,000 0,17751953 0,1791553 ! DNA recombination GO:0006310 146 92 0,000 0,17751953 0,17907672 ! sulfur metabolic process GO:0006790 118 92 0,000 0,17751953 0,17899821 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,17926949 0,18068353 ! electron transport chain GO:0022900 123 94 0,000 0,18101583 0,18236373 ! response to oxidative stress GO:0006979 141 94 0,000 0,18101583 0,18228389 ! regulation of binding GO:0051098 151 95 0,000 0,18275855 0,18395827 ! angiogenesis GO:0001525 149 95 0,000 0,18275855 0,1838778 ! carboxylic acid transport GO:0046942 147 95 0,000 0,18275855 0,1837974 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,18449766 0,1854653 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,18449766 0,18538428 ! protein maturation GO:0051604 129 96 0,000 0,18449766 0,18530332 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,18623317 0,18696477 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,18623317 0,1868832 ! extracellular structure organization GO:0043062 156 99 0,000 0,18969341 0,1902725 ! protein import GO:0017038 156 99 0,000 0,18969341 0,19018956 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,18969341 0,19010669 ! regulation of translation GO:0006417 151 100 0,000 0,19141817 0,19175165 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,19141817 0,19166817 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,19141817 0,19158476 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,19141817 0,19150143 ! protein localization in organelle GO:0033365 161 100 0,000 0,19141817 0,19141817