pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1266-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of blood coagulation GO:0030193 40 25 5,000 1,252E-09 3,013E-06 ! regulation of coagulation GO:0050818 46 29 5,000 3,309E-09 3,981E-06 ! negative regulation of blood coagulation GO:0030195 24 17 4,000 1,033E-08 8,285E-06 ! negative regulation of coagulation GO:0050819 29 20 4,000 2,56E-08 1,54E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 8,616E-08 4,146E-05 ! response to hypoxia GO:0001666 171 81 6,000 8,628E-08 3,46E-05 ! response to oxygen levels GO:0070482 176 83 6,000 1,023E-07 3,515E-05 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 6,04E-07 1,817E-04 ! stem cell division GO:0017145 11 5 2,000 8,948E-07 2,392E-04 GO:0048103|somatic stem cell division, ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 1,462E-06 3,519E-04 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 3,000 1,463E-06 3,2E-04 ! nuclear migration GO:0007097 12 6 2,000 1,784E-06 3,576E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,784E-06 3,301E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 1,822E-06 3,131E-04 ! cell growth GO:0016049 84 45 4,000 1,843E-06 2,956E-04 ! apoptotic nuclear changes GO:0030262 32 22 3,000 2,732E-06 4,108E-04 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 3,111E-06 4,403E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 3,111E-06 4,158E-04 ! macrophage differentiation GO:0030225 11 7 2,000 3,111E-06 3,939E-04 ! fibrinolysis GO:0042730 10 7 2,000 3,111E-06 3,742E-04 ! positive regulation of fibroblast proliferation GO:0048146 43 24 3,000 3,941E-06 4,515E-04 ! negative regulation of multicellular organismal process GO:0051241 166 93 5,000 4,191E-06 4,584E-04 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 4,961E-06 5,19E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 4,961E-06 4,973E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 6,44E-06 6,198E-04 ! middle ear morphogenesis GO:0042474 14 9 2,000 7,417E-06 6,864E-04 ! regulation of protein complex assembly GO:0043254 117 61 4,000 8,468E-06 7,546E-04 ! negative regulation of protein complex assembly GO:0031333 59 29 3,000 8,655E-06 7,437E-04 ! ear development GO:0043583 103 62 4,000 9,178E-06 7,615E-04 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 9,933E-06 7,966E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,056E-05 8,196E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 1,074E-05 8,072E-04 ! cell projection assembly GO:0030031 120 66 4,000 1,249E-05 9,109E-04 ! detection of mechanical stimulus GO:0050982 22 11 2,000 1,447E-05 1,024E-03 ! nucleus localization GO:0051647 19 11 2,000 1,447E-05 9,949E-04 ! regulation of B cell proliferation GO:0030888 20 12 2,000 1,923E-05 1,285E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,923E-05 1,251E-03 ! nucleus organization GO:0006997 67 38 3,000 2,606E-05 1,65E-03 ! regulation of peptidase activity GO:0052547 134 79 4,000 3,006E-05 1,855E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 3,006E-05 1,808E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 3,393E-05 1,991E-03 GO:0045937|positive regulation of phosphate metabolic process, ! JAK-STAT cascade GO:0007259 71 44 3,000 4,694E-05 2,689E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 4,831E-05 2,703E-03 ! filopodium assembly GO:0046847 32 16 2,000 4,831E-05 2,642E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 5,603E-05 2,996E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 5,847E-05 3,058E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 5,847E-05 2,993E-03 ! microspike assembly GO:0030035 36 17 2,000 5,847E-05 2,931E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 6,591E-05 3,236E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 6,635E-05 3,193E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 6,993E-05 3,299E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 7,295E-05 3,375E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 8,277E-05 3,758E-03 ! regulation of endothelial cell migration GO:0010594 44 19 2,000 8,277E-05 3,688E-03 ! interphase GO:0051325 213 98 4,000 8,458E-05 3,7E-03 ! cell cycle arrest GO:0007050 213 100 4,000 9,309E-05 4E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 9,706E-05 4,097E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 9,706E-05 4,026E-03 ! inner ear receptor cell differentiation GO:0060113 37 20 2,000 9,706E-05 3,958E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 1,129E-04 4,526E-03 ! regulation of vasoconstriction GO:0019229 39 21 2,000 1,129E-04 4,452E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 1,135E-04 4,404E-03 ! positive regulation of organelle organization GO:0010638 100 56 3,000 1,218E-04 4,651E-03 ! mechanoreceptor differentiation GO:0042490 40 22 2,000 1,302E-04 4,897E-03 ! positive regulation of cytoskeleton organization GO:0051495 48 22 2,000 1,302E-04 4,821E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,302E-04 4,748E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,305E-04 4,687E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 1,305E-04 4,618E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,493E-04 5,206E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 1,493E-04 5,131E-03 GO:0010810|regulation of cell-substrate adhesion, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 1,701E-04 5,763E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 1,701E-04 5,683E-03 ! membrane depolarization GO:0051899 39 24 2,000 1,701E-04 5,605E-03 ! regulation of smooth muscle contraction GO:0006940 43 25 2,000 1,926E-04 6,262E-03 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 1,000 2,006E-04 6,436E-03 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of viral genome replication GO:0045070 9 5 1,000 2,006E-04 6,352E-03 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 1,000 2,006E-04 6,269E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 2,006E-04 6,189E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,006E-04 6,11E-03 ! microvillus organization GO:0032528 7 5 1,000 2,006E-04 6,034E-03 GO:0030033|microvillus assembly, ! muscle cell migration GO:0014812 8 5 1,000 2,006E-04 5,959E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,006E-04 5,887E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,006E-04 5,816E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 2,006E-04 5,747E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 2,006E-04 5,679E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,006E-04 5,613E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 2,17E-04 6,002E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 2,17E-04 5,933E-03 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 2,000 2,17E-04 5,867E-03 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 2,17E-04 5,802E-03 ! actin filament organization GO:0007015 148 66 3,000 2,308E-04 6,102E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 2,433E-04 6,364E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,433E-04 6,295E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,446E-04 6,26E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 2,446E-04 6,194E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 2,59E-04 6,49E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 2,739E-04 6,795E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 3,001E-04 7,367E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! vascular smooth muscle contraction GO:0014829 13 6 1,000 3,001E-04 7,292E-03 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 3,001E-04 7,219E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of platelet activation GO:0010544 9 6 1,000 3,001E-04 7,148E-03 GO:0010543|regulation of platelet activation, ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 3,001E-04 7,078E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,001E-04 7,009E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 3,001E-04 6,942E-03 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 3,02E-04 6,92E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 3,02E-04 6,854E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 3,226E-04 7,254E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 3,226E-04 7,187E-03 ! cell junction assembly GO:0034329 78 30 2,000 3,344E-04 7,382E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 3,344E-04 7,315E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 3,583E-04 7,767E-03 ! organelle localization GO:0051640 136 74 3,000 3,583E-04 7,697E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 3,69E-04 7,858E-03 ! response to mechanical stimulus GO:0009612 57 32 2,000 4,059E-04 8,566E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,188E-04 8,763E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,188E-04 8,687E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,188E-04 8,613E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 4,188E-04 8,54E-03 ! positive regulation of heart rate GO:0010460 10 7 1,000 4,188E-04 8,468E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 4,188E-04 8,398E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! phasic smooth muscle contraction GO:0014821 12 7 1,000 4,188E-04 8,328E-03 ! vesicle fusion GO:0006906 17 7 1,000 4,188E-04 8,26E-03 ! diuresis GO:0030146 12 7 1,000 4,188E-04 8,193E-03 GO:0030147|natriuresis, ! negative regulation of nucleotide metabolic process GO:0045980 11 7 1,000 4,188E-04 8,127E-03 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 4,188E-04 8,062E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 4,188E-04 7,998E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 4,188E-04 7,935E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 4,45E-04 8,365E-03 GO:0060326|cell chemotaxis, ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 4,598E-04 8,576E-03 ! negative regulation of secretion GO:0051048 63 35 2,000 5,303E-04 9,815E-03 ! calcium-mediated signaling GO:0019722 62 35 2,000 5,303E-04 9,74E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 5,568E-04 0,01014866 ! generation of neurons in the forebrain GO:0021872 18 8 1,000 5,568E-04 0,01007236 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 5,568E-04 9,997E-03 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 5,568E-04 9,923E-03 ! ER overload response GO:0006983 12 8 1,000 5,568E-04 9,85E-03 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 5,568E-04 9,778E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 5,568E-04 9,707E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 5,568E-04 9,638E-03 ! DNA topological change GO:0006265 12 8 1,000 5,568E-04 9,569E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 5,568E-04 9,501E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,568E-04 9,434E-03 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 2,000 5,766E-04 9,702E-03 ! cell junction organization GO:0034330 86 36 2,000 5,766E-04 9,634E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 5,766E-04 9,568E-03 ! negative regulation of growth GO:0045926 155 84 3,000 5,803E-04 9,563E-03 ! regulation of ligase activity GO:0051340 142 84 3,000 5,803E-04 9,498E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 6,254E-04 0,01016735 ! regulation of protein transport GO:0051223 154 87 3,000 6,625E-04 0,0106977 GO:0070201|regulation of establishment of protein localization, ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 7,137E-04 0,0114485 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 7,137E-04 0,01137268 GO:0010469|regulation of receptor activity, ! gas homeostasis GO:0033483 16 9 1,000 7,137E-04 0,01129786 ! renal water homeostasis GO:0003091 14 9 1,000 7,137E-04 0,01122402 ! induction of an organ GO:0001759 14 9 1,000 7,137E-04 0,01115113 ! regulation of cell division GO:0051302 15 9 1,000 7,137E-04 0,01107919 ! regulation of telomere maintenance GO:0032204 14 9 1,000 7,137E-04 0,01100817 ! regulation of muscle adaptation GO:0043502 14 9 1,000 7,137E-04 0,01093806 ! ear morphogenesis GO:0042471 60 39 2,000 7,308E-04 0,01112828 ! regulation of cell cycle process GO:0010564 149 90 3,000 7,526E-04 0,01138857 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 8,895E-04 0,01337651 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 8,895E-04 0,01329342 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 8,895E-04 0,01321137 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 8,895E-04 0,01313031 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 8,895E-04 0,01305025 ! positive regulation of heart contraction GO:0045823 16 10 1,000 8,895E-04 0,01297116 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 8,895E-04 0,01289302 ! DNA ligation GO:0006266 19 10 1,000 8,895E-04 0,01281582 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 8,895E-04 0,01273953 ! midbrain development GO:0030901 13 10 1,000 8,895E-04 0,01266415 ! multicellular organismal water homeostasis GO:0050891 15 10 1,000 8,895E-04 0,01258965 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 8,895E-04 0,01251603 ! localization within membrane GO:0051668 20 10 1,000 8,895E-04 0,01244326 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 9,09E-04 0,01264128 ! forebrain development GO:0030900 188 95 3,000 9,215E-04 0,01274267 ! leukocyte differentiation GO:0002521 202 96 3,000 9,583E-04 0,01317488 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 9,739E-04 0,01331384 ! regulation of protein localization GO:0032880 176 97 3,000 9,96E-04 0,01353918 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,084E-03 0,01465232 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,084E-03 0,01457046 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,084E-03 0,01448951 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,084E-03 0,01440946 ! substrate-bound cell migration GO:0006929 13 11 1,000 1,084E-03 0,01433029 ! vasoconstriction GO:0042310 18 11 1,000 1,084E-03 0,01425198 ! neuroblast proliferation GO:0007405 24 11 1,000 1,084E-03 0,01417452 ! developmental induction GO:0031128 19 11 1,000 1,084E-03 0,0140979 GO:0045168|cell-cell signaling involved in cell fate specification, ! leukocyte migration GO:0050900 68 45 2,000 1,112E-03 0,01439051 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 1,112E-03 0,01431356 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,112E-03 0,01423742 ! ATP synthesis coupled electron transport GO:0042773 64 45 2,000 1,112E-03 0,01416209 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,186E-03 0,01502091 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,186E-03 0,01494226 ! protein homooligomerization GO:0051260 76 47 2,000 1,263E-03 0,01582578 ! cartilage condensation GO:0001502 20 12 1,000 1,297E-03 0,01616829 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,297E-03 0,01608495 ! focal adhesion formation GO:0048041 35 12 1,000 1,297E-03 0,01600246 ! entry into host cell GO:0030260 32 12 1,000 1,297E-03 0,01592082 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 1,297E-03 0,01584 ! gland morphogenesis GO:0022612 29 12 1,000 1,297E-03 0,01576 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,297E-03 0,0156808 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,297E-03 0,0156024 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,297E-03 0,01552477 ! cellular component disassembly GO:0022411 86 48 2,000 1,343E-03 0,01599246 ! activation of caspase activity GO:0006919 84 48 2,000 1,343E-03 0,01591368 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,343E-03 0,01583567 ! detection of abiotic stimulus GO:0009582 74 49 2,000 1,426E-03 0,01673105 ! regulation of cell projection organization GO:0031344 121 50 2,000 1,512E-03 0,01765445 ! regulation of ossification GO:0030278 117 50 2,000 1,512E-03 0,01756916 ! inner ear development GO:0048839 79 50 2,000 1,512E-03 0,0174847 ! lipid localization GO:0010876 28 13 1,000 1,528E-03 0,01759301 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 1,528E-03 0,01750923 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 1,528E-03 0,01742625 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,528E-03 0,01734405 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,528E-03 0,01726262 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 1,528E-03 0,01718195 ! actin filament polymerization GO:0030041 24 13 1,000 1,528E-03 0,01710204 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 1,601E-03 0,01783073 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,601E-03 0,01774856 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 2,000 1,693E-03 0,0186873 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,693E-03 0,01860197 ! cartilage development GO:0051216 90 52 2,000 1,693E-03 0,01851742 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,778E-03 0,01935332 ! regulation of heart rate GO:0002027 24 14 1,000 1,778E-03 0,01926615 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 1,778E-03 0,01917975 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,778E-03 0,01909413 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,778E-03 0,01900927 ! respiratory electron transport chain GO:0022904 76 53 2,000 1,789E-03 0,01904468 ! regulation of protein polymerization GO:0032271 103 53 2,000 1,789E-03 0,01896078 ! response to UV GO:0009411 104 53 2,000 1,789E-03 0,01887762 ! activation of phospholipase C activity GO:0007202 103 54 2,000 1,888E-03 0,01983552 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,99E-03 0,02082018 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 1,99E-03 0,02073005 ! positive regulation of cell size GO:0045793 27 15 1,000 2,045E-03 0,02120914 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 2,045E-03 0,02111811 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! regulation of vasodilation GO:0042312 26 15 1,000 2,045E-03 0,02102786 ! water homeostasis GO:0030104 27 15 1,000 2,045E-03 0,02093838 ! regulation of bone remodeling GO:0046850 137 57 2,000 2,205E-03 0,02248236 ! regulation of phospholipase activity GO:0010517 106 57 2,000 2,205E-03 0,0223875 ! regulation of intracellular transport GO:0032386 101 57 2,000 2,205E-03 0,02229343 ! regulation of tissue remodeling GO:0034103 140 58 2,000 2,318E-03 0,02333436 ! positive regulation of lipase activity GO:0060193 108 58 2,000 2,318E-03 0,02323714 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,33E-03 0,02326492 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 2,33E-03 0,02316878 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 2,33E-03 0,02307344 ! activation of MAPKK activity GO:0000186 35 16 1,000 2,33E-03 0,02297887 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,33E-03 0,02288508 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,33E-03 0,02279205 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! skeletal system morphogenesis GO:0048705 105 59 2,000 2,434E-03 0,02371023 ! DNA catabolic process GO:0006308 86 59 2,000 2,434E-03 0,02361463 ! establishment of organelle localization GO:0051656 109 59 2,000 2,434E-03 0,02351979 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 2,633E-03 0,02534267 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 2,633E-03 0,0252417 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 2,633E-03 0,02514153 ! regulation of viral genome replication GO:0045069 28 17 1,000 2,633E-03 0,02504216 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 2,633E-03 0,02494357 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,633E-03 0,02484575 ! neutrophil chemotaxis GO:0030593 27 17 1,000 2,633E-03 0,0247487 ! regulation of homeostatic process GO:0032844 134 62 2,000 2,804E-03 0,0262509 ! regulation of mitosis GO:0007088 105 63 2,000 2,935E-03 0,02736674 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 2,000 2,935E-03 0,02726107 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 2,954E-03 0,02733305 GO:0050886|endocrine process, ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 2,954E-03 0,02722832 ! patterning of blood vessels GO:0001569 39 18 1,000 2,954E-03 0,0271244 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,954E-03 0,02702126 ! myeloid cell differentiation GO:0030099 111 65 2,000 3,207E-03 0,02922562 ! positive regulation of hormone secretion GO:0046887 32 19 1,000 3,291E-03 0,0298839 ! G1 phase GO:0051318 40 19 1,000 3,291E-03 0,02977155 ! peptide hormone secretion GO:0030072 31 19 1,000 3,291E-03 0,02966005 ! lung development GO:0030324 144 67 2,000 3,494E-03 0,0313679 ! regulation of lipase activity GO:0060191 130 68 2,000 3,643E-03 0,03258676 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,646E-03 0,03249333 ! response to alkaloid GO:0043279 38 20 1,000 3,646E-03 0,03237343 ! cellular response to starvation GO:0009267 33 20 1,000 3,646E-03 0,03225441 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 3,646E-03 0,03213626 ! body fluid secretion GO:0007589 31 20 1,000 3,646E-03 0,03201898 ! peptide secretion GO:0002790 35 20 1,000 3,646E-03 0,03190255 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 3,646E-03 0,03178696 ! peptidyl-serine modification GO:0018209 43 20 1,000 3,646E-03 0,0316722 ! negative regulation of T cell activation GO:0050868 40 20 1,000 3,646E-03 0,03155827 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 3,796E-03 0,03273952 ! respiratory tube development GO:0030323 150 70 2,000 3,954E-03 0,03397191 ! hormone secretion GO:0046879 38 21 1,000 4,018E-03 0,03440609 ! inactivation of MAPK activity GO:0000188 39 21 1,000 4,018E-03 0,03428408 ! smooth muscle contraction GO:0006939 46 21 1,000 4,018E-03 0,03416294 ! positive regulation of locomotion GO:0040017 39 21 1,000 4,018E-03 0,03404265 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 4,018E-03 0,0339232 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 4,114E-03 0,03461305 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 4,279E-03 0,03587453 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 4,279E-03 0,03574997 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 4,279E-03 0,03562627 ! respiratory system development GO:0060541 153 72 2,000 4,279E-03 0,03550342 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,407E-03 0,03643843 ! microtubule-based transport GO:0010970 54 22 1,000 4,407E-03 0,03631365 ! regulation of chemotaxis GO:0050920 40 22 1,000 4,407E-03 0,03618971 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 4,407E-03 0,03606661 ! renal system process GO:0003014 41 22 1,000 4,407E-03 0,03594435 ! positive regulation of B cell activation GO:0050871 38 22 1,000 4,407E-03 0,03582292 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 4,407E-03 0,0357023 ! regulation of transcription factor activity GO:0051090 126 74 2,000 4,621E-03 0,03730857 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 2,000 4,621E-03 0,0371838 ! cell-matrix adhesion GO:0007160 163 75 2,000 4,798E-03 0,03847797 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 4,798E-03 0,03835014 ! positive regulation of DNA replication GO:0045740 43 23 1,000 4,813E-03 0,03834185 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,813E-03 0,03821531 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,813E-03 0,03808961 ! barbed-end actin filament capping GO:0051016 50 23 1,000 4,813E-03 0,03796472 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 1,000 4,813E-03 0,03784065 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 4,813E-03 0,03771739 ! hormone transport GO:0009914 40 23 1,000 4,813E-03 0,03759494 ! regulation of actin filament-based process GO:0032970 152 77 2,000 5,164E-03 0,04020546 ! positive regulation of ligase activity GO:0051351 124 77 2,000 5,164E-03 0,04007576 ! regulation of transmembrane transport GO:0034762 38 24 1,000 5,235E-03 0,04049743 ! vesicle docking GO:0048278 47 24 1,000 5,235E-03 0,04036764 ! regulation of behavior GO:0050795 43 24 1,000 5,235E-03 0,04023866 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 5,235E-03 0,04011052 ! blood coagulation GO:0007596 146 78 2,000 5,353E-03 0,04088339 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 2,000 5,353E-03 0,04075401 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 5,546E-03 0,04209133 ! activation of protein kinase activity GO:0032147 147 79 2,000 5,546E-03 0,04195897 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,673E-03 0,0427887 ! vasculogenesis GO:0001570 46 25 1,000 5,673E-03 0,04265499 ! chromosome condensation GO:0030261 45 25 1,000 5,673E-03 0,04252211 ! response to starvation GO:0042594 42 25 1,000 5,673E-03 0,04239005 ! osteoblast differentiation GO:0001649 60 25 1,000 5,673E-03 0,04225881 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,673E-03 0,04212838 ! neural crest cell development GO:0014032 54 25 1,000 5,673E-03 0,04199876 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 5,673E-03 0,04186993 ! somitogenesis GO:0001756 43 25 1,000 5,673E-03 0,04174188 ! cellular response to nutrient levels GO:0031669 41 25 1,000 5,673E-03 0,04161462 ! cell-substrate adhesion GO:0031589 171 81 2,000 5,944E-03 0,04347188 ! embryonic pattern specification GO:0009880 44 26 1,000 6,128E-03 0,04467743 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 6,128E-03 0,04454245 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 6,128E-03 0,04440829 ! initiation of viral infection GO:0019059 57 26 1,000 6,128E-03 0,04427493 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 6,128E-03 0,04414237 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 6,128E-03 0,0440106 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 6,128E-03 0,04387962 ! hemostasis GO:0007599 158 84 2,000 6,574E-03 0,04693426 ! negative regulation of transport GO:0051051 153 84 2,000 6,574E-03 0,0467954 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 6,599E-03 0,04683244 ! iron ion transport GO:0006826 59 27 1,000 6,599E-03 0,0466947 ! protein amino acid acylation GO:0043543 55 27 1,000 6,599E-03 0,04655777 ! regulation of chromosome organization GO:0033044 42 27 1,000 6,599E-03 0,04642163 ! glutathione metabolic process GO:0006749 39 27 1,000 6,599E-03 0,04628629 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 6,599E-03 0,04615174 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 6,599E-03 0,04601797 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 6,599E-03 0,04588497 ! oxidative phosphorylation GO:0006119 133 86 2,000 7,015E-03 0,04863867 ! tube morphogenesis GO:0035239 176 86 2,000 7,015E-03 0,0484989 ! mitochondrion organization GO:0007005 148 86 2,000 7,015E-03 0,04835993 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 7,085E-03 0,0487062 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 7,085E-03 0,04856744 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 7,085E-03 0,04842946 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 7,085E-03 0,04829227 ! cellular respiration GO:0045333 135 88 2,000 7,473E-03 0,05079005 ! positive regulation of protein modification process GO:0031401 136 88 2,000 7,473E-03 0,05064698 ! regulation of DNA binding GO:0051101 155 88 2,000 7,473E-03 0,05050471 ! regulation of pH GO:0006885 43 29 1,000 7,588E-03 0,05113754 ! respiratory gaseous exchange GO:0007585 57 29 1,000 7,588E-03 0,0509947 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 7,588E-03 0,05085266 ! regulation of cell adhesion GO:0030155 212 89 2,000 7,708E-03 0,05151751 ! ossification GO:0001503 188 90 2,000 7,948E-03 0,05297338 ! membrane docking GO:0022406 61 30 1,000 8,106E-03 0,05387469 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 8,106E-03 0,05372627 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 8,106E-03 0,05357867 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 8,106E-03 0,05343188 ! bone development GO:0060348 189 91 2,000 8,192E-03 0,05385514 ! cholesterol homeostasis GO:0042632 53 31 1,000 8,639E-03 0,05663872 GO:0055092|sterol homeostasis, ! peptide transport GO:0015833 55 31 1,000 8,639E-03 0,05648481 ! triglyceride metabolic process GO:0006641 43 31 1,000 8,639E-03 0,05633174 ! mesoderm formation GO:0001707 69 31 1,000 8,639E-03 0,05617949 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 8,639E-03 0,05602806 GO:0043433|negative regulation of transcription factor activity, ! regulation of membrane potential GO:0042391 164 93 2,000 8,694E-03 0,05623072 ! cholesterol transport GO:0030301 56 32 1,000 9,188E-03 0,05926828 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 9,188E-03 0,05910981 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 9,188E-03 0,05895218 ! BMP signaling pathway GO:0030509 64 32 1,000 9,188E-03 0,05879539 ! hindbrain development GO:0030902 61 32 1,000 9,188E-03 0,05863944 ! detection of stimulus GO:0051606 151 96 2,000 9,48E-03 0,06033825 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 9,75E-03 0,06189785 ! formation of primary germ layer GO:0001704 72 33 1,000 9,752E-03 0,06174804 ! cell fate specification GO:0001708 52 33 1,000 9,752E-03 0,06158597 ! sterol transport GO:0015918 57 33 1,000 9,752E-03 0,06142475 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01030527 0,06473754 GO:0060538|skeletal muscle organ development, ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01033151 0,06473339 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01033151 0,06456525 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01033151 0,06439798 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01033151 0,06423158 ! regulation of muscle development GO:0048634 70 35 1,000 0,01092553 0,06774953 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01092553 0,06757536 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01092553 0,06740209 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,01092553 0,06722971 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01092553 0,06705821 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01153429 0,07061448 ! tissue remodeling GO:0048771 76 37 1,000 0,01215765 0,07424189 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01215765 0,07405394 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01215765 0,07386693 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,01215765 0,07368087 ! regulation of protein stability GO:0031647 73 37 1,000 0,01215765 0,07349574 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01215765 0,07331154 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01279547 0,07696478 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,01279547 0,07677285 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 1,000 0,01279547 0,07658187 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01279547 0,07639184 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,01279547 0,07620275 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01344762 0,07988883 ! segmentation GO:0035282 67 39 1,000 0,01344762 0,07969206 ! organic ether metabolic process GO:0018904 55 39 1,000 0,01344762 0,07949625 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,01411395 0,08323077 ! negative regulation of binding GO:0051100 72 40 1,000 0,01411395 0,08302727 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01411395 0,08282476 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,01479431 0,08660612 ! gliogenesis GO:0042063 88 41 1,000 0,01479431 0,08639591 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,01479431 0,08618672 ! T cell differentiation GO:0030217 81 41 1,000 0,01479431 0,08597853 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01479431 0,08577136 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,01479431 0,08556518 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01548858 0,08936576 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01548858 0,08915197 ! regulation of tube size GO:0035150 71 42 1,000 0,01548858 0,08893919 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,01548858 0,08872743 ! regulation of protein secretion GO:0050708 71 42 1,000 0,01548858 0,08851668 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01548858 0,08830692 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,01619661 0,09212541 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01619661 0,09190813 ! glucose transport GO:0015758 65 43 1,000 0,01619661 0,09169188 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01619661 0,09147664 ! hexose transport GO:0008645 67 44 1,000 0,01691827 0,09532872 GO:0015749|monosaccharide transport, ! maintenance of location in cell GO:0051651 97 44 1,000 0,01691827 0,09510599 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,01765343 0,09900732 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01765343 0,09877707 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01765343 0,09854789 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,01840194 0,10248856 ! pigmentation GO:0043473 100 46 1,000 0,01840194 0,10225187 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01916367 0,10623915 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01916367 0,10599492 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01916367 0,10575182 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,0199385 0,1097758 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0199385 0,10952517 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02072628 0,11359324 ! peptide metabolic process GO:0006518 76 49 1,000 0,02072628 0,11333508 ! histone modification GO:0016570 91 50 1,000 0,0215269 0,11744605 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,0215269 0,11718034 ! positive regulation of binding GO:0051099 78 51 1,000 0,02234021 0,12133304 ! viral infectious cycle GO:0019058 99 51 1,000 0,02234021 0,12105977 ! excretion GO:0007588 83 51 1,000 0,02234021 0,12078772 ! vesicle organization GO:0016050 107 51 1,000 0,02234021 0,1205169 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02237708 0,12044578 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02237708 0,12017693 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02237708 0,11990927 ! neuron fate determination GO:0048664 7 5 0,000 0,02237708 0,11964281 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02237708 0,11937753 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02237708 0,11911342 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02237708 0,11885047 ! polyol transport GO:0015791 12 5 0,000 0,02237708 0,11858869 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02237708 0,11832805 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02237708 0,11806856 ! response to superoxide GO:0000303 10 5 0,000 0,02237708 0,11781021 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02237708 0,11755298 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02237708 0,11729687 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02237708 0,11704188 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02237708 0,11678799 ! female meiosis GO:0007143 7 5 0,000 0,02237708 0,1165352 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02237708 0,11628351 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02237708 0,1160329 ! cobalt ion transport GO:0006824 11 5 0,000 0,02237708 0,11578336 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02237708 0,1155349 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02237708 0,1152875 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02237708 0,11504116 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02237708 0,11479587 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02237708 0,11455163 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02237708 0,11430842 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02237708 0,11406624 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02237708 0,11382508 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02237708 0,11358495 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02237708 0,11334582 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02237708 0,1131077 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02237708 0,11287057 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02237708 0,11263444 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02237708 0,1123993 ! negative chemotaxis GO:0050919 14 5 0,000 0,02237708 0,11216513 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02237708 0,11193194 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02237708 0,11169972 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02237708 0,11146846 ! behavioral response to pain GO:0048266 9 5 0,000 0,02237708 0,11123815 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02237708 0,11100879 ! Notch receptor processing GO:0007220 8 5 0,000 0,02237708 0,11078038 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02237708 0,1105529 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02237708 0,11032636 ! micturition GO:0060073 9 5 0,000 0,02237708 0,11010074 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02237708 0,10987605 ! copulation GO:0007620 9 5 0,000 0,02237708 0,10965227 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02237708 0,1094294 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02237708 0,10920743 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02237708 0,10898636 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02237708 0,10876619 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02237708 0,1085469 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02237708 0,1083285 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02237708 0,10811097 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02237708 0,10789432 ! grooming behavior GO:0007625 6 5 0,000 0,02237708 0,10767853 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02237708 0,1074636 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02237708 0,10724953 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02237708 0,10703631 ! response to protozoan GO:0001562 10 5 0,000 0,02237708 0,10682394 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02237708 0,1066124 ! lymph vessel development GO:0001945 10 5 0,000 0,02237708 0,10640171 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02237708 0,10619184 ! endochondral ossification GO:0001958 16 5 0,000 0,02237708 0,1059828 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02237708 0,10577459 ! parathyroid gland development GO:0060017 13 5 0,000 0,02237708 0,10556718 ! anagen GO:0042640 6 5 0,000 0,02237708 0,1053606 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02237708 0,10515481 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02237708 0,10494983 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02237708 0,10474565 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02237708 0,10454226 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02237708 0,10433966 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02237708 0,10413784 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02237708 0,1039368 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02237708 0,10373654 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02237708 0,10353705 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02237708 0,10333832 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02237708 0,10314035 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02237708 0,10294314 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02237708 0,10274669 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02237708 0,10255098 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02237708 0,10235602 ! histidine catabolic process GO:0006548 6 5 0,000 0,02237708 0,10216179 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02237708 0,1019683 ! valine metabolic process GO:0006573 10 5 0,000 0,02237708 0,10177555 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02237708 0,10158352 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02237708 0,10139221 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02237708 0,10120162 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02237708 0,10101175 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02237708 0,10082259 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02237708 0,10063414 ! polyol catabolic process GO:0046174 7 5 0,000 0,02237708 0,10044639 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02237708 0,10025934 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02237708 0,10007298 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02237708 0,09988732 ! mitochondrial fission GO:0000266 8 5 0,000 0,02237708 0,09970234 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02237708 0,09951805 ! mRNA transcription GO:0009299 9 5 0,000 0,02237708 0,09933444 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02237708 0,0991515 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02237708 0,09896924 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02237708 0,09878764 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02237708 0,09860671 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02237708 0,09842644 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02237708 0,09824683 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02237708 0,09806788 ! response to food GO:0032094 6 5 0,000 0,02237708 0,09788957 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02237708 0,09771191 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02237708 0,0975349 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02237708 0,09735852 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02237708 0,09718279 ! forebrain neuron development GO:0021884 13 5 0,000 0,02237708 0,09700768 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02237708 0,09683321 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02237708 0,09665936 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02237708 0,09648614 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02237708 0,09631353 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02237708 0,09614154 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02237708 0,09597017 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02237708 0,0957994 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02237708 0,09562924 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02237708 0,09545969 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02237708 0,09529073 ! basic amino acid transport GO:0015802 11 5 0,000 0,02237708 0,09512237 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02237708 0,09495461 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02237708 0,09478744 ! depyrimidination GO:0045008 10 5 0,000 0,02237708 0,09462085 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02237708 0,09445485 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02237708 0,09428943 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02237708 0,09412459 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02237708 0,09396032 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02237708 0,09379663 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02237708 0,0936335 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02237708 0,09347094 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02237708 0,09330895 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02237708 0,09314752 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02237708 0,09298664 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02237708 0,09282632 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02237708 0,09266655 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02237708 0,09250733 ! response to arsenic GO:0046685 10 5 0,000 0,02237708 0,09234865 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02237708 0,09219052 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02237708 0,09203293 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02237708 0,09187588 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02237708 0,09171936 ! response to cadmium ion GO:0046686 7 5 0,000 0,02237708 0,09156337 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02237708 0,09140792 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02237708 0,09125299 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02237708 0,09109859 ! decidualization GO:0046697 11 5 0,000 0,02237708 0,0909447 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02237708 0,09079134 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02237708 0,09063849 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02237708 0,09048616 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02237708 0,09033434 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02237708 0,09018302 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02237708 0,09003221 ! neural tube patterning GO:0021532 7 5 0,000 0,02237708 0,08988191 ! embryonic cleavage GO:0040016 6 5 0,000 0,02237708 0,08973211 ! peroxisome fission GO:0016559 5 5 0,000 0,02237708 0,0895828 ! histone demethylation GO:0016577 10 5 0,000 0,02237708 0,08943399 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02237708 0,08928568 ! mitotic recombination GO:0006312 9 5 0,000 0,02237708 0,08913785 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02237708 0,08899052 ! metaphase plate congression GO:0051310 7 5 0,000 0,02237708 0,08884367 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02237708 0,08869731 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02237708 0,08855142 ! enteric nervous system development GO:0048484 8 5 0,000 0,02237708 0,08840602 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02237708 0,08826109 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02237708 0,08811664 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02237708 0,08797265 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02237708 0,08782914 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02237708 0,0876861 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02237708 0,08754352 ! plasminogen activation GO:0031639 5 5 0,000 0,02237708 0,0874014 ! B cell homeostasis GO:0001782 13 5 0,000 0,02237708 0,08725975 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02237708 0,08711855 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02237708 0,08697781 ! metaphase GO:0051323 8 5 0,000 0,02237708 0,08683752 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02237708 0,08669769 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02237708 0,0865583 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02237708 0,08641936 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02237708 0,08628087 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02237708 0,08614282 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02237708 0,08600521 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02237708 0,08586804 ! response to redox state GO:0051775 5 5 0,000 0,02237708 0,08573131 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02237708 0,08559501 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02237708 0,08545915 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02237708 0,08532372 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02237708 0,08518871 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02237708 0,08505413 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02237708 0,08491998 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02237708 0,08478624 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02237708 0,08465293 ! striatum development GO:0021756 9 5 0,000 0,02237708 0,08452004 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02237708 0,08438756 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02237708 0,0842555 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02237708 0,08412385 ! glial cell migration GO:0008347 11 5 0,000 0,02237708 0,08399261 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02237708 0,08386178 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02237708 0,08373136 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02237708 0,08360134 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02237708 0,08347173 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02237708 0,08334251 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02237708 0,0832137 ! neuroprotection GO:0043526 6 5 0,000 0,02237708 0,08308528 ! neural plate development GO:0001840 8 5 0,000 0,02237708 0,08295726 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02237708 0,08282964 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02237708 0,0827024 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02237708 0,08257556 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02237708 0,0824491 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02237708 0,08232303 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02237708 0,08219735 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02237708 0,08207205 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02237708 0,08194713 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02237708 0,08182259 ! spindle assembly GO:0051225 6 5 0,000 0,02237708 0,08169843 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02237708 0,08157464 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02237708 0,08145123 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02237708 0,08132819 ! drug metabolic process GO:0017144 6 5 0,000 0,02237708 0,08120553 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02237708 0,08108323 ! organ regeneration GO:0031100 7 5 0,000 0,02237708 0,0809613 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02237708 0,08083974 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02237708 0,08071854 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02237708 0,0805977 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,02316609 0,08331481 ! membrane fusion GO:0006944 110 52 1,000 0,02316609 0,08319046 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02316609 0,08306648 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,02400441 0,08594435 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,02485504 0,0888577 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,02485504 0,08872586 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02571786 0,09166989 ! aging GO:0007568 103 55 1,000 0,02571786 0,09153429 ! gastrulation GO:0007369 112 55 1,000 0,02571786 0,09139908 ! regulation of actin filament length GO:0030832 105 56 1,000 0,02659274 0,09436894 ! regulation of DNA replication GO:0006275 101 56 1,000 0,02659274 0,09422996 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02679249 0,09479814 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02679249 0,09465893 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02679249 0,09452013 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02679249 0,09438175 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02679249 0,09424376 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02679249 0,09410618 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02679249 0,093969 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02679249 0,09383222 ! sleep GO:0030431 13 6 0,000 0,02679249 0,09369583 ! response to oxygen radical GO:0000305 11 6 0,000 0,02679249 0,09355984 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02679249 0,09342425 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02679249 0,09328905 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02679249 0,09315424 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02679249 0,09301982 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02679249 0,09288578 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02679249 0,09275213 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02679249 0,09261887 ! forebrain regionalization GO:0021871 8 6 0,000 0,02679249 0,09248599 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02679249 0,09235348 ! male meiosis GO:0007140 7 6 0,000 0,02679249 0,09222136 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02679249 0,09208962 ! response to zinc ion GO:0010043 9 6 0,000 0,02679249 0,09195825 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02679249 0,09182725 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02679249 0,09169663 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02679249 0,09156638 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02679249 0,0914365 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02679249 0,09130699 ! malate metabolic process GO:0006108 11 6 0,000 0,02679249 0,09117784 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02679249 0,09104906 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02679249 0,09092064 ! protein refolding GO:0042026 15 6 0,000 0,02679249 0,09079258 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02679249 0,09066488 ! opsonization GO:0008228 8 6 0,000 0,02679249 0,09053754 ! mating behavior GO:0007617 7 6 0,000 0,02679249 0,09041056 ! neuron remodeling GO:0016322 15 6 0,000 0,02679249 0,09028394 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02679249 0,09015767 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02679249 0,09003175 ! equilibrioception GO:0050957 14 6 0,000 0,02679249 0,08990618 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02679249 0,08978096 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02679249 0,08965609 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02679249 0,08953157 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02679249 0,0894074 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02679249 0,08928356 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02679249 0,08916007 ! toxin metabolic process GO:0009404 11 6 0,000 0,02679249 0,08903692 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02679249 0,08891411 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02679249 0,08879164 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02679249 0,08866951 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02679249 0,08854771 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02679249 0,08842624 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02679249 0,08830511 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02679249 0,08818431 ! thymic T cell selection GO:0045061 12 6 0,000 0,02679249 0,08806384 ! protein lipoylation GO:0009249 10 6 0,000 0,02679249 0,0879437 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02679249 0,08782389 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02679249 0,0877044 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02679249 0,08758523 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02679249 0,08746639 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02679249 0,08734788 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,02679249 0,08722968 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02679249 0,0871118 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02679249 0,08699424 ! hyperosmotic response GO:0006972 9 6 0,000 0,02679249 0,086877 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02679249 0,08676007 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02679249 0,08664346 ! urea metabolic process GO:0019627 7 6 0,000 0,02679249 0,08652716 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02679249 0,08641117 ! neutrophil activation GO:0042119 8 6 0,000 0,02679249 0,08629549 ! regulation of appetite GO:0032098 9 6 0,000 0,02679249 0,08618012 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02679249 0,08606506 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02679249 0,08595031 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02679249 0,08583586 ! neuron apoptosis GO:0051402 9 6 0,000 0,02679249 0,08572172 ! nucleoside salvage GO:0043174 9 6 0,000 0,02679249 0,08560788 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02679249 0,08549434 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02679249 0,0853811 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02679249 0,08526816 ! male sex determination GO:0030238 15 6 0,000 0,02679249 0,08515552 ! carnitine transport GO:0015879 10 6 0,000 0,02679249 0,08504318 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02679249 0,08493114 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02679249 0,08481938 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02679249 0,08470793 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02679249 0,08459676 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02679249 0,08448589 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02679249 0,0843753 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02679249 0,08426501 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02679249 0,084155 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02679249 0,08404528 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02679249 0,08393585 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02679249 0,0838267 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02679249 0,08371783 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02679249 0,08360925 ! neural nucleus development GO:0048857 14 6 0,000 0,02679249 0,08350095 ! response to UV-C GO:0010225 11 6 0,000 0,02679249 0,08339293 ! astrocyte development GO:0014002 15 6 0,000 0,02679249 0,08328518 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02679249 0,08317772 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02679249 0,08307053 ! interaction with symbiont GO:0051702 13 6 0,000 0,02679249 0,08296362 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02679249 0,08285698 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02679249 0,08275062 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02679249 0,08264453 ! response to copper ion GO:0046688 10 6 0,000 0,02679249 0,08253871 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02679249 0,08243316 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02679249 0,08232788 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02679249 0,08222287 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02679249 0,08211813 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02679249 0,08201365 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02679249 0,08190944 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02679249 0,0818055 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02679249 0,08170181 ! hair follicle maturation GO:0048820 7 6 0,000 0,02679249 0,08159839 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02679249 0,08149524 ! Schwann cell development GO:0014044 15 6 0,000 0,02679249 0,08139234 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02679249 0,0812897 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02679249 0,08118732 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02679249 0,0810852 ! subpallium development GO:0021544 10 6 0,000 0,02679249 0,08098333 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02679249 0,08088172 ! histone ubiquitination GO:0016574 8 6 0,000 0,02679249 0,08078037 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02679249 0,08067926 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02679249 0,08057841 ! G2 phase GO:0051319 16 6 0,000 0,02679249 0,08047782 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02679249 0,08037747 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02679249 0,08027737 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02679249 0,08017753 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02679249 0,08007793 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02679249 0,07997858 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02679249 0,07987947 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02679249 0,07978061 ! receptor internalization GO:0031623 10 6 0,000 0,02679249 0,07968199 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02679249 0,07958362 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02679249 0,07948549 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02679249 0,0793876 ! protein deubiquitination GO:0016579 14 6 0,000 0,02679249 0,07928995 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02679249 0,07919255 ! protein destabilization GO:0031648 9 6 0,000 0,02679249 0,07909538 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02679249 0,07899845 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02679249 0,07890175 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02679249 0,0788053 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02679249 0,07870907 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02679249 0,07861309 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02679249 0,07851733 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02679249 0,07842181 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02679249 0,07832653 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02679249 0,07823147 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02679249 0,07813664 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02679249 0,07804205 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02679249 0,07794768 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02679249 0,07785354 ! catecholamine transport GO:0051937 9 6 0,000 0,02679249 0,07775963 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02679249 0,07766594 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02679249 0,07757248 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02679249 0,07747925 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02679249 0,07738623 ! maternal placenta development GO:0001893 12 6 0,000 0,02679249 0,07729344 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02679249 0,07720088 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02679249 0,07710853 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02679249 0,07701641 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02679249 0,0769245 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02679249 0,07683282 ! maintenance of location GO:0051235 118 57 1,000 0,02747956 0,07870932 ! regulation of endocytosis GO:0030100 91 58 1,000 0,02837819 0,0811866 ! positive regulation of secretion GO:0051047 95 59 1,000 0,02928851 0,0836914 ! regulation of cellular component size GO:0032535 109 59 1,000 0,02928851 0,08359212 ! regulation of heart contraction GO:0008016 110 60 1,000 0,0302104 0,08612111 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,0302104 0,08601919 ! kidney development GO:0001822 122 60 1,000 0,0302104 0,08591752 ! mesoderm development GO:0007498 119 61 1,000 0,03114373 0,08846731 ! tRNA transcription GO:0009304 14 7 0,000 0,0311881 0,08848888 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0311881 0,08838465 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0311881 0,08828067 ! regulation of helicase activity GO:0051095 15 7 0,000 0,0311881 0,08817693 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0311881 0,08807344 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0311881 0,08797019 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0311881 0,08786718 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0311881 0,08776441 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0311881 0,08766188 ! prostate gland development GO:0030850 13 7 0,000 0,0311881 0,08755959 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0311881 0,08745754 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0311881 0,08735573 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0311881 0,08725415 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0311881 0,08715281 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0311881 0,08705171 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0311881 0,08695083 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0311881 0,0868502 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0311881 0,08674979 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0311881 0,08664962 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0311881 0,08654968 ! glycolipid transport GO:0046836 10 7 0,000 0,0311881 0,08644997 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0311881 0,08635048 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,0311881 0,08625123 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0311881 0,0861522 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0311881 0,08605341 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0311881 0,08595483 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0311881 0,08585649 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0311881 0,08575837 ! mRNA stabilization GO:0048255 18 7 0,000 0,0311881 0,08566047 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,0311881 0,08556279 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0311881 0,08546534 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0311881 0,08536811 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0311881 0,0852711 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0311881 0,08517431 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0311881 0,08507774 ! lipoprotein transport GO:0042953 14 7 0,000 0,0311881 0,08498139 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0311881 0,08488526 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0311881 0,08478934 ! rhythmic behavior GO:0007622 15 7 0,000 0,0311881 0,08469365 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0311881 0,08459816 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0311881 0,08450289 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0311881 0,08440784 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0311881 0,084313 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0311881 0,08421837 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0311881 0,08412396 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0311881 0,08402975 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0311881 0,08393576 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0311881 0,08384198 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0311881 0,0837484 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0311881 0,08365504 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0311881 0,08356188 ! spinal cord patterning GO:0021511 13 7 0,000 0,0311881 0,08346893 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0311881 0,08337619 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0311881 0,08328365 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0311881 0,08319132 ! adrenal gland development GO:0030325 17 7 0,000 0,0311881 0,08309919 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0311881 0,08300727 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0311881 0,08291555 ! ovulation GO:0030728 9 7 0,000 0,0311881 0,08282403 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0311881 0,08273271 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0311881 0,0826416 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0311881 0,08255068 ! microtubule nucleation GO:0007020 20 7 0,000 0,0311881 0,08245997 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0311881 0,08236945 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0311881 0,08227913 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0311881 0,08218901 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0311881 0,08209909 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0311881 0,08200937 ! galactose metabolic process GO:0006012 13 7 0,000 0,0311881 0,08191984 ! response to dietary excess GO:0002021 8 7 0,000 0,0311881 0,0818305 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0311881 0,08174136 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0311881 0,08165242 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0311881 0,08156366 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0311881 0,0814751 ! organ growth GO:0035265 15 7 0,000 0,0311881 0,08138674 ! purine salvage GO:0043101 10 7 0,000 0,0311881 0,08129856 ! nucleoside transport GO:0015858 8 7 0,000 0,0311881 0,08121057 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0311881 0,08112278 ! parturition GO:0007567 14 7 0,000 0,0311881 0,08103517 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0311881 0,08094776 ! rRNA modification GO:0000154 14 7 0,000 0,0311881 0,08086053 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0311881 0,08077349 ! spindle checkpoint GO:0031577 15 7 0,000 0,0311881 0,08068663 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0311881 0,08059997 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0311881 0,08051349 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0311881 0,08042719 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0311881 0,08034108 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0311881 0,08025516 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0311881 0,08016941 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,0311881 0,08008385 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0311881 0,07999848 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0311881 0,07991328 ! eating behavior GO:0042755 7 7 0,000 0,0311881 0,07982827 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0311881 0,07974343 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0311881 0,07965878 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0311881 0,07957431 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0311881 0,07949001 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0311881 0,07940589 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0311881 0,07932196 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0311881 0,07923819 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0311881 0,07915461 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0311881 0,0790712 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0311881 0,07898797 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0311881 0,07890491 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0311881 0,07882203 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0311881 0,07873932 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0311881 0,07865678 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0311881 0,07857442 ! regulation of meiosis GO:0040020 12 7 0,000 0,0311881 0,07849223 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0311881 0,07841021 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0311881 0,07832836 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0311881 0,07824668 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0311881 0,07816518 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0311881 0,07808384 ! transcription termination GO:0006353 13 7 0,000 0,0311881 0,07800267 ! response to tumor cell GO:0002347 13 7 0,000 0,0311881 0,07792167 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,0311881 0,07784084 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0311881 0,07776018 ! anaphase GO:0051322 17 7 0,000 0,0311881 0,07767968 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0311881 0,07759935 ! axonal fasciculation GO:0007413 18 7 0,000 0,0311881 0,07751918 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0311881 0,07743918 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0311881 0,07735935 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0311881 0,07727968 ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0311881 0,07720018 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0311881 0,07712083 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0311881 0,07704165 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0311881 0,07696264 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0311881 0,07688378 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0311881 0,07680509 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0311881 0,07672655 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0311881 0,07664818 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0311881 0,07656997 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0311881 0,07649192 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0311881 0,07641402 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0311881 0,07633629 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0311881 0,07625871 ! lymph node development GO:0048535 10 7 0,000 0,0311881 0,07618129 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0311881 0,07610403 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0311881 0,07602692 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0311881 0,07594997 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0311881 0,07587318 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0311881 0,07579654 ! adult feeding behavior GO:0008343 9 7 0,000 0,0311881 0,07572005 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0311881 0,07564372 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0311881 0,07556754 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0311881 0,07549152 ! muscle adaptation GO:0043500 14 7 0,000 0,0311881 0,07541565 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0311881 0,07533993 ! retina homeostasis GO:0001895 12 7 0,000 0,0311881 0,07526436 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0311881 0,07518895 ! protein prenylation GO:0018342 18 7 0,000 0,0311881 0,07511368 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0311881 0,07503857 ! viral reproductive process GO:0022415 126 62 1,000 0,03208839 0,07712753 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,03304425 0,07934577 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,0340112 0,08158618 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,035564 0,08522609 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,035564 0,08514128 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,035564 0,08505665 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,035564 0,08497219 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,035564 0,08488789 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,035564 0,08480376 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,035564 0,08471979 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,035564 0,084636 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,035564 0,08455236 ! meiotic prophase I GO:0007128 13 8 0,000 0,035564 0,0844689 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,035564 0,08438559 ! oligopeptide transport GO:0006857 15 8 0,000 0,035564 0,08430245 ! UTP metabolic process GO:0046051 8 8 0,000 0,035564 0,08421948 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,035564 0,08413667 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,035564 0,08405402 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,035564 0,08397153 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,035564 0,08388921 ! succinate metabolic process GO:0006105 14 8 0,000 0,035564 0,08380704 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,035564 0,08372504 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,035564 0,0836432 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,035564 0,08356151 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,035564 0,08347999 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,035564 0,08339863 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,035564 0,08331742 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,035564 0,08323637 ! reflex GO:0060004 16 8 0,000 0,035564 0,08315548 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,035564 0,08307475 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,035564 0,08299417 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,035564 0,08291375 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,035564 0,08283349 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,035564 0,08275338 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,035564 0,08267342 ! pigment granule organization GO:0048753 16 8 0,000 0,035564 0,08259362 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,035564 0,08251397 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,035564 0,08243448 ! astrocyte differentiation GO:0048708 18 8 0,000 0,035564 0,08235514 ! histidine metabolic process GO:0006547 16 8 0,000 0,035564 0,08227595 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,035564 0,08219692 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,035564 0,08211803 ! glycine catabolic process GO:0006546 13 8 0,000 0,035564 0,0820393 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,035564 0,08196072 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,035564 0,08188229 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,035564 0,08180401 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,035564 0,08172588 ! melanin metabolic process GO:0006582 15 8 0,000 0,035564 0,08164789 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,035564 0,08157006 ! macrophage activation GO:0042116 12 8 0,000 0,035564 0,08149237 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,035564 0,08141483 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,035564 0,08133744 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,035564 0,0812602 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,035564 0,0811831 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,035564 0,08110615 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,035564 0,08102935 ! osteoblast development GO:0002076 16 8 0,000 0,035564 0,08095269 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,035564 0,08087617 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,035564 0,0807998 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,035564 0,08072358 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,035564 0,08064749 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,035564 0,08057155 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,035564 0,08049576 ! response to UV-B GO:0010224 16 8 0,000 0,035564 0,0804201 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,035564 0,08034459 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,035564 0,08026922 ! intermediate filament organization GO:0045109 12 8 0,000 0,035564 0,08019399 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,035564 0,08011891 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,035564 0,08004396 ! cellular extravasation GO:0045123 12 8 0,000 0,035564 0,07996915 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,035564 0,07989448 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,035564 0,07981995 ! response to antibiotic GO:0046677 11 8 0,000 0,035564 0,07974556 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,035564 0,07967131 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,035564 0,0795972 ! response to tropane GO:0014073 15 8 0,000 0,035564 0,07952323 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,035564 0,07944939 ! melanosome transport GO:0032402 13 8 0,000 0,035564 0,07937569 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,035564 0,07930212 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,035564 0,0792287 ! mast cell activation GO:0045576 14 8 0,000 0,035564 0,0791554 ! multicellular organismal aging GO:0010259 18 8 0,000 0,035564 0,07908225 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,035564 0,07900923 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,035564 0,07893634 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,035564 0,07886359 ! nucleosome disassembly GO:0006337 14 8 0,000 0,035564 0,07879097 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,035564 0,07871848 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,035564 0,07864613 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,035564 0,07857391 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,035564 0,07850183 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,035564 0,07842987 ! intracellular lipid transport GO:0032365 13 8 0,000 0,035564 0,07835805 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,035564 0,07828636 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,035564 0,0782148 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,035564 0,07814337 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,035564 0,07807207 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,035564 0,0780009 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,035564 0,07792986 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,035564 0,07785895 ! hormone catabolic process GO:0042447 17 8 0,000 0,035564 0,07778817 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,035564 0,07771752 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,035564 0,077647 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,035564 0,0775766 ! ATP catabolic process GO:0006200 11 8 0,000 0,035564 0,07750633 ! blastocyst growth GO:0001832 19 8 0,000 0,035564 0,07743619 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,035564 0,07736618 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,035564 0,07729629 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,035564 0,07722653 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,035564 0,07715689 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,035564 0,07708738 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,035564 0,07701799 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,035564 0,07694873 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,035564 0,0768796 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,035564 0,07681058 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,035564 0,0767417 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,035564 0,07667293 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,035564 0,07660429 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,035564 0,07653577 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,035564 0,07646737 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,035564 0,0763991 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,035564 0,07633095 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,035564 0,07626292 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,03697739 0,07922315 ! activation of MAPK activity GO:0000187 115 67 1,000 0,03697739 0,07915266 ! chromosome segregation GO:0007059 113 67 1,000 0,03697739 0,07908231 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,03798751 0,08117047 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,03798751 0,08109845 ! viral reproduction GO:0016032 134 68 1,000 0,03798751 0,08102655 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,03798751 0,08095478 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,03900814 0,08305627 ! urogenital system development GO:0001655 137 69 1,000 0,03900814 0,08298283 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03992029 0,08484824 ! axon extension GO:0048675 15 9 0,000 0,03992029 0,08477335 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03992029 0,08469859 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03992029 0,08462397 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03992029 0,08454948 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03992029 0,08447511 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03992029 0,08440088 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03992029 0,08432678 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03992029 0,08425281 ! phosphate transport GO:0006817 19 9 0,000 0,03992029 0,08417897 ! reproductive behavior GO:0019098 19 9 0,000 0,03992029 0,08410526 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03992029 0,08403168 ! CTP metabolic process GO:0046036 9 9 0,000 0,03992029 0,08395822 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03992029 0,0838849 ! GTP metabolic process GO:0046039 9 9 0,000 0,03992029 0,0838117 ! RNA methylation GO:0001510 15 9 0,000 0,03992029 0,08373863 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03992029 0,08366568 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03992029 0,08359287 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03992029 0,08352018 ! artery development GO:0060840 24 9 0,000 0,03992029 0,08344762 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03992029 0,08337518 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03992029 0,08330287 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03992029 0,08323068 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03992029 0,08315862 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03992029 0,08308668 ! chemosensory behavior GO:0007635 20 9 0,000 0,03992029 0,08301487 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03992029 0,08294318 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03992029 0,08287162 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03992029 0,08280018 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03992029 0,08272886 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03992029 0,08265766 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03992029 0,08258659 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03992029 0,08251564 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03992029 0,08244481 ! protein targeting to ER GO:0045047 22 9 0,000 0,03992029 0,0823741 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03992029 0,08230352 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03992029 0,08223305 ! T cell selection GO:0045058 23 9 0,000 0,03992029 0,08216271 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,03992029 0,08209248 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03992029 0,08202238 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03992029 0,08195239 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03992029 0,08188253 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03992029 0,08181278 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03992029 0,08174315 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03992029 0,08167364 ! mannose metabolic process GO:0006013 13 9 0,000 0,03992029 0,08160425 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03992029 0,08153498 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03992029 0,08146582 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03992029 0,08139678 ! receptor clustering GO:0043113 18 9 0,000 0,03992029 0,08132786 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03992029 0,08125906 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03992029 0,08119037 ! ruffle organization GO:0031529 15 9 0,000 0,03992029 0,0811218 ! retinol metabolic process GO:0042572 18 9 0,000 0,03992029 0,08105334 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03992029 0,080985 ! behavioral fear response GO:0001662 22 9 0,000 0,03992029 0,08091677 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03992029 0,08084866 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03992029 0,08078066 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03992029 0,08071278 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03992029 0,08064501 ! protein heterooligomerization GO:0051291 16 9 0,000 0,03992029 0,08057735 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03992029 0,08050981 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03992029 0,08044238 ! segment specification GO:0007379 13 9 0,000 0,03992029 0,08037507 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03992029 0,08030786 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03992029 0,08024077 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03992029 0,08017379 ! response to amine stimulus GO:0014075 13 9 0,000 0,03992029 0,08010693 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03992029 0,08004017 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03992029 0,07997353 ! erythrocyte development GO:0048821 15 9 0,000 0,03992029 0,07990699 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03992029 0,07984057 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03992029 0,07977426 ! postreplication repair GO:0006301 22 9 0,000 0,03992029 0,07970805 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03992029 0,07964196 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03992029 0,07957598 ! icosanoid secretion GO:0032309 15 9 0,000 0,03992029 0,0795101 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03992029 0,07944434 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03992029 0,07937868 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03992029 0,07931313 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03992029 0,07924769 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03992029 0,07918236 ! sterol catabolic process GO:0016127 11 9 0,000 0,03992029 0,07911714 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03992029 0,07905202 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03992029 0,07898701 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03992029 0,07892211 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03992029 0,07885731 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03992029 0,07879262 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03992029 0,07872804 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03992029 0,07866356 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03992029 0,07859919 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03992029 0,07853492 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03992029 0,07847076 ! purine base metabolic process GO:0006144 21 9 0,000 0,03992029 0,0784067 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03992029 0,07834275 ! pigment granule transport GO:0051904 17 9 0,000 0,03992029 0,0782789 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03992029 0,07821515 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03992029 0,07815151 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03992029 0,07808797 ! mitochondrion localization GO:0051646 15 9 0,000 0,03992029 0,07802454 ! humoral immune response GO:0006959 109 71 1,000 0,04108045 0,08022693 ! carbohydrate transport GO:0008643 110 72 1,000 0,04213192 0,08221362 ! learning or memory GO:0007611 147 73 1,000 0,04319343 0,08421669 ! regulation of blood pressure GO:0008217 125 73 1,000 0,04319343 0,0841485 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04425703 0,08615083 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04425703 0,08608118 ! synapsis GO:0007129 13 10 0,000 0,04425703 0,08601165 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04425703 0,08594223 ! N-glycan processing GO:0006491 20 10 0,000 0,04425703 0,08587292 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04425703 0,08580373 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04425703 0,08573464 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04425703 0,08566567 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04425703 0,0855968 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04425703 0,08552805 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04425703 0,08545941 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04425703 0,08539088 ! androgen metabolic process GO:0008209 17 10 0,000 0,04425703 0,08532246 ! phospholipid efflux GO:0033700 16 10 0,000 0,04425703 0,08525414 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04425703 0,08518594 ! lung alveolus development GO:0048286 26 10 0,000 0,04425703 0,08511784 ! pathogenesis GO:0009405 13 10 0,000 0,04425703 0,08504986 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04425703 0,08498198 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04425703 0,08491421 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04425703 0,08484655 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04425703 0,084779 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04425703 0,08471155 ! endoderm development GO:0007492 16 10 0,000 0,04425703 0,08464422 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04425703 0,08457698 ! arginine catabolic process GO:0006527 13 10 0,000 0,04425703 0,08450986 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04425703 0,08444284 ! proline metabolic process GO:0006560 13 10 0,000 0,04425703 0,08437593 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04425703 0,08430912 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04425703 0,08424242 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04425703 0,08417583 ! V(D)J recombination GO:0033151 28 10 0,000 0,04425703 0,08410934 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04425703 0,08404296 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04425703 0,08397668 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04425703 0,0839105 ! B cell proliferation GO:0042100 18 10 0,000 0,04425703 0,08384443 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04425703 0,08377846 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04425703 0,0837126 ! multicellular organism growth GO:0035264 18 10 0,000 0,04425703 0,08364684 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04425703 0,08358118 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04425703 0,08351563 ! epithelial cell development GO:0002064 20 10 0,000 0,04425703 0,08345018 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04425703 0,08338483 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04425703 0,08331958 ! macroautophagy GO:0016236 17 10 0,000 0,04425703 0,08325444 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04425703 0,08318939 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04425703 0,08312445 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04425703 0,08305961 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04425703 0,08299487 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04425703 0,08293024 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04425703 0,0828657 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04425703 0,08280126 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04425703 0,08273693 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04425703 0,08267269 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04425703 0,08260855 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04425703 0,08254451 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04425703 0,08248058 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04425703 0,08241674 ! response to dsRNA GO:0043331 20 10 0,000 0,04425703 0,082353 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04425703 0,08228935 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04425703 0,08222581 ! melanosome localization GO:0032400 16 10 0,000 0,04425703 0,08216236 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04425703 0,08209902 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04425703 0,08203577 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04425703 0,08197261 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04425703 0,08190956 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04425703 0,0818466 ! mRNA cleavage GO:0006379 17 10 0,000 0,04425703 0,08178374 ! protein sumoylation GO:0016925 15 10 0,000 0,04425703 0,08172097 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04425703 0,0816583 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04425703 0,08159573 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04425703 0,08153325 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04425703 0,08147087 ! salivary gland development GO:0007431 27 10 0,000 0,04425703 0,08140858 ! prophase GO:0051324 15 10 0,000 0,04425703 0,08134639 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04425703 0,08128429 ! apical protein localization GO:0045176 15 10 0,000 0,04425703 0,08122229 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04425703 0,08116038 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04425703 0,08109857 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04425703 0,08103685 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04425703 0,08097523 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04425703 0,0809137 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04425703 0,08085226 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04425703 0,08079091 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04425703 0,08072966 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04425703 0,0806685 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04425703 0,08060744 ! oocyte development GO:0048599 17 10 0,000 0,04425703 0,08054646 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04425703 0,08048558 ! blastocyst formation GO:0001825 17 10 0,000 0,04425703 0,08042479 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04425703 0,08036409 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04425703 0,08030349 ! activation of innate immune response GO:0002218 12 10 0,000 0,04425703 0,08024297 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04425703 0,08018255 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04425703 0,08012222 ! response to nicotine GO:0035094 20 10 0,000 0,04425703 0,08006197 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04425703 0,08000182 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04425703 0,07994176 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04425703 0,07988179 ! transition metal ion transport GO:0000041 126 74 1,000 0,04426489 0,07983607 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,04534618 0,08172503 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,04534618 0,08166385 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04534618 0,08160278 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,0464372 0,08350366 ! defense response to bacterium GO:0042742 89 76 1,000 0,0464372 0,08344129 ! neuropeptide signaling pathway GO:0007218 107 77 1,000 0,04753783 0,08535523 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,04753783 0,08529158 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04857434 0,08708633 ! respiratory burst GO:0045730 17 11 0,000 0,04857434 0,08702149 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04857434 0,08695674 ! neuron fate specification GO:0048665 17 11 0,000 0,04857434 0,08689209 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04857434 0,08682753 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04857434 0,08676307 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04857434 0,08669871 ! thyroid gland development GO:0030878 26 11 0,000 0,04857434 0,08663444 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04857434 0,08657026 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04857434 0,08650618 ! response to pain GO:0048265 24 11 0,000 0,04857434 0,0864422 ! T cell proliferation GO:0042098 26 11 0,000 0,04857434 0,08637831 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04857434 0,08631452 ! bone resorption GO:0045453 16 11 0,000 0,04857434 0,08625082 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04857434 0,08618721 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04857434 0,0861237 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04857434 0,08606028 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04857434 0,08599695 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04857434 0,08593372 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04857434 0,08587058 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04857434 0,08580753 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04857434 0,08574457 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04857434 0,08568171 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04857434 0,08561894 ! lipid digestion GO:0044241 18 11 0,000 0,04857434 0,08555626 ! UV protection GO:0009650 19 11 0,000 0,04857434 0,08549368 ! adult heart development GO:0007512 14 11 0,000 0,04857434 0,08543118 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04857434 0,08536878 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04857434 0,08530646 ! temperature homeostasis GO:0001659 17 11 0,000 0,04857434 0,08524424 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04857434 0,08518211 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04857434 0,08512007 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04857434 0,08505812 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04857434 0,08499626 ! regulation of organ growth GO:0046620 13 11 0,000 0,04857434 0,08493449 ! pigment granule localization GO:0051875 20 11 0,000 0,04857434 0,08487281 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04857434 0,08481122 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04857434 0,08474971 ! embryonic axis specification GO:0000578 18 11 0,000 0,04857434 0,0846883 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04857434 0,08462698 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04857434 0,08456574 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04857434 0,0845046 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04857434 0,08444354 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04857434 0,08438257 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04857434 0,08432168 ! zymogen activation GO:0031638 15 11 0,000 0,04857434 0,08426089 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04857434 0,08420018 ! nucleosome positioning GO:0016584 15 11 0,000 0,04857434 0,08413956 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04857434 0,08407903 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04857434 0,08401859 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04857434 0,08395823 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04857434 0,08389796 ! acid secretion GO:0046717 18 11 0,000 0,04857434 0,08383777 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04857434 0,08377767 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04857434 0,08371766 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04857434 0,08365773 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04857434 0,08359789 ! oocyte differentiation GO:0009994 18 11 0,000 0,04857434 0,08353814 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04857434 0,08347847 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04857434 0,08341888 ! cholesterol efflux GO:0033344 19 11 0,000 0,04857434 0,08335938 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04857434 0,08329997 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04857434 0,08324064 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04857434 0,08318139 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04857434 0,08312223 ! embryonic gut development GO:0048566 15 11 0,000 0,04857434 0,08306315 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04857434 0,08300416 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04857434 0,08294525 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04857434 0,08288642 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04857434 0,08282768 ! defense response to fungus GO:0050832 13 11 0,000 0,04857434 0,08276902 ! lysogeny GO:0030069 21 11 0,000 0,04857434 0,08271044 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04857434 0,08265195 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04857434 0,08259354 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04857434 0,08253521 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04857434 0,08247696 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04857434 0,0824188 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04857434 0,08236072 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,04864796 0,08242747 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,0497675 0,08426504 ! T cell activation GO:0042110 168 81 1,000 0,05203436 0,08804126 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,05203436 0,08797939 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05287228 0,08933336 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05287228 0,08927067 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05287228 0,08920807 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05287228 0,08914556 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05287228 0,08908313 ! virus-host interaction GO:0019048 29 12 0,000 0,05287228 0,08902079 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05287228 0,08895854 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05287228 0,08889637 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05287228 0,08883429 ! protein complex disassembly GO:0043241 27 12 0,000 0,05287228 0,0887723 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05287228 0,0887104 ! hippocampus development GO:0021766 26 12 0,000 0,05287228 0,08864858 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05287228 0,08858684 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05287228 0,0885252 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05287228 0,08846364 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05287228 0,08840216 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05287228 0,08834077 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05287228 0,08827946 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05287228 0,08821824 ! drug transport GO:0015893 16 12 0,000 0,05287228 0,08815711 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05287228 0,08809606 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05287228 0,08803509 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05287228 0,08797421 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05287228 0,08791341 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05287228 0,0878527 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05287228 0,08779207 ! forebrain cell migration GO:0021885 21 12 0,000 0,05287228 0,08773152 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05287228 0,08767106 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05287228 0,08761068 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05287228 0,08755038 ! fear response GO:0042596 26 12 0,000 0,05287228 0,08749017 ! monoamine transport GO:0015844 18 12 0,000 0,05287228 0,08743004 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05287228 0,08736999 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05287228 0,08731003 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05287228 0,08725014 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05287228 0,08719034 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05287228 0,08713062 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05287228 0,08707098 ! protein homotetramerization GO:0051289 21 12 0,000 0,05287228 0,08701143 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05287228 0,08695195 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05287228 0,08689256 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05287228 0,08683325 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05287228 0,08677402 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05287228 0,08671487 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05287228 0,0866558 ! cranial nerve development GO:0021545 20 12 0,000 0,05287228 0,08659681 ! fucose catabolic process GO:0019317 22 12 0,000 0,05287228 0,0865379 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05287228 0,08647907 ! histone methylation GO:0016571 26 12 0,000 0,05287228 0,08642032 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05287228 0,08636165 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05287228 0,08630306 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05287228 0,08624455 ! T cell homeostasis GO:0043029 25 12 0,000 0,05287228 0,08618612 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05287228 0,08612776 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05287228 0,08606949 ! spleen development GO:0048536 22 12 0,000 0,05287228 0,0860113 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05287228 0,08595318 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05287228 0,08589514 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05287228 0,08583718 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05287228 0,0857793 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05287228 0,0857215 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05287228 0,08566378 ! response to cold GO:0009409 17 12 0,000 0,05287228 0,08560613 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05287228 0,08554856 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05287228 0,08549107 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,05318147 0,08593326 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,05550253 0,08962354 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,05550253 0,08956343 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,05667627 0,09139618 GO:0002696|positive regulation of leukocyte activation, ! cGMP metabolic process GO:0046068 18 13 0,000 0,05715095 0,09209993 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05715095 0,09203828 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05715095 0,09197671 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05715095 0,09191523 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05715095 0,09185383 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05715095 0,09179252 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05715095 0,09173128 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05715095 0,09167013 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05715095 0,09160905 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05715095 0,09154806 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05715095 0,09148715 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05715095 0,09142632 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05715095 0,09136557 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05715095 0,09130491 ! methionine metabolic process GO:0006555 27 13 0,000 0,05715095 0,09124432 ! plasma membrane organization GO:0007009 24 13 0,000 0,05715095 0,09118381 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05715095 0,09112339 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05715095 0,09106304 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05715095 0,09100277 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05715095 0,09094258 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05715095 0,09088248 ! response to X-ray GO:0010165 25 13 0,000 0,05715095 0,09082245 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05715095 0,0907625 ! exocrine system development GO:0035272 32 13 0,000 0,05715095 0,09070263 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05715095 0,09064284 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05715095 0,09058313 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05715095 0,09052349 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05715095 0,09046394 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05715095 0,09040446 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05715095 0,09034506 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05715095 0,09028574 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05715095 0,0902265 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05715095 0,09016734 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05715095 0,09010825 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05715095 0,09004924 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05715095 0,08999031 ! ribosome assembly GO:0042255 17 13 0,000 0,05715095 0,08993145 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05715095 0,08987267 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05715095 0,08981397 ! chromatin silencing GO:0006342 26 13 0,000 0,05715095 0,08975534 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05715095 0,0896968 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05715095 0,08963832 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05715095 0,08957993 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05715095 0,08952161 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05715095 0,08946336 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05715095 0,08940519 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05715095 0,0893471 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05715095 0,08928908 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05715095 0,08923114 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05715095 0,08917327 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05715095 0,08911548 ! embryonic placenta development GO:0001892 23 13 0,000 0,05715095 0,08905776 ! insulin secretion GO:0030073 23 13 0,000 0,05715095 0,08900012 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05715095 0,08894255 ! acrosome reaction GO:0007340 18 13 0,000 0,05715095 0,08888506 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,05904967 0,09177876 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 206 88 1,000 0,06024913 0,09358258 ! regulation of neurological system process GO:0031644 148 88 1,000 0,06024913 0,0935222 ! rRNA transcription GO:0009303 25 14 0,000 0,06141043 0,09526338 ! lactation GO:0007595 26 14 0,000 0,06141043 0,095202 ! reproductive cellular process GO:0048610 20 14 0,000 0,06141043 0,0951407 ! tRNA modification GO:0006400 20 14 0,000 0,06141043 0,09507947 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06141043 0,09501833 ! regulation of S phase GO:0033261 23 14 0,000 0,06141043 0,09495726 ! water transport GO:0006833 21 14 0,000 0,06141043 0,09489628 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06141043 0,09483537 ! non-recombinational repair GO:0000726 25 14 0,000 0,06141043 0,09477454 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06141043 0,09471378 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06141043 0,09465311 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06141043 0,09459251 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06141043 0,09453199 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06141043 0,09447155 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06141043 0,09441118 ! palate development GO:0060021 31 14 0,000 0,06141043 0,0943509 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,06141043 0,09429069 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06141043 0,09423055 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06141043 0,09417049 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06141043 0,09411051 ! arginine metabolic process GO:0006525 17 14 0,000 0,06141043 0,09405061 ! organic alcohol transport GO:0015850 29 14 0,000 0,06141043 0,09399078 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06141043 0,09393103 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06141043 0,09387135 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06141043 0,09381175 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06141043 0,09375222 ! L-amino acid transport GO:0015807 30 14 0,000 0,06141043 0,09369277 ! bone mineralization GO:0030282 17 14 0,000 0,06141043 0,0936334 ! stem cell development GO:0048864 43 14 0,000 0,06141043 0,0935741 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06141043 0,09351488 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06141043 0,09345573 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06141043 0,09339665 ! cerebellum development GO:0021549 21 14 0,000 0,06141043 0,09333765 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06141043 0,09327873 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06141043 0,09321988 ! response to gamma radiation GO:0010332 28 14 0,000 0,06141043 0,0931611 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06141043 0,0931024 ! cofactor transport GO:0051181 26 14 0,000 0,06141043 0,09304377 ! NADP metabolic process GO:0006739 24 14 0,000 0,06141043 0,09298521 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06141043 0,09292673 ! intestinal absorption GO:0050892 25 14 0,000 0,06141043 0,09286832 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06141043 0,09280999 ! oxygen transport GO:0015671 21 14 0,000 0,06141043 0,09275173 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06141043 0,09269354 ! male genitalia development GO:0030539 24 14 0,000 0,06141043 0,09263543 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06141043 0,09257738 ! regulation of axon extension GO:0030516 37 14 0,000 0,06141043 0,09251941 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06141043 0,09246152 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,06267308 0,09430358 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06565081 0,09872241 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06565081 0,09866075 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,06565081 0,09859916 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06565081 0,09853765 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06565081 0,09847622 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06565081 0,09841487 ! copper ion transport GO:0006825 20 15 0,000 0,06565081 0,09835359 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06565081 0,09829238 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06565081 0,09823126 ! sulfate transport GO:0008272 23 15 0,000 0,06565081 0,09817021 ! response to cAMP GO:0051591 22 15 0,000 0,06565081 0,09810923 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06565081 0,09804833 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06565081 0,09798751 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06565081 0,09792676 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06565081 0,09786608 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06565081 0,09780549 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06565081 0,09774496 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06565081 0,09768451 ! pituitary gland development GO:0021983 29 15 0,000 0,06565081 0,09762414 ! vesicle coating GO:0006901 33 15 0,000 0,06565081 0,09756384 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06565081 0,09750362 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06565081 0,09744347 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,06565081 0,09738339 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06565081 0,09732339 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,06565081 0,09726346 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06565081 0,09720361 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06565081 0,09714383 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06565081 0,09708412 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06565081 0,09702448 ! histone deacetylation GO:0016575 20 15 0,000 0,06565081 0,09696492 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06565081 0,09690544 ! tissue regeneration GO:0042246 26 15 0,000 0,06565081 0,09684602 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06565081 0,09678668 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06565081 0,09672741 ! muscle maintenance GO:0046716 26 15 0,000 0,06565081 0,09666821 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06565081 0,09660909 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06565081 0,09655004 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06565081 0,09649106 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06565081 0,09643215 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06565081 0,09637331 ! cell killing GO:0001906 29 15 0,000 0,06565081 0,09631455 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06565081 0,09625586 ! detection of bacterium GO:0016045 18 15 0,000 0,06565081 0,09619724 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06565081 0,09613869 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06565081 0,09608021 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06565081 0,0960218 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06565081 0,09596346 ! peptide hormone processing GO:0016486 23 15 0,000 0,06565081 0,0959052 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,06637007 0,09689708 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,06637007 0,09683832 ! transcription initiation GO:0006352 153 94 1,000 0,0676183 0,09859977 ! regulation of T cell activation GO:0050863 158 94 1,000 0,0676183 0,09854005 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06987218 0,10176299 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06987218 0,10170143 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06987218 0,10163994 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06987218 0,10157853 ! bone remodeling GO:0046849 27 16 0,000 0,06987218 0,10151719 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06987218 0,10145592 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06987218 0,10139473 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06987218 0,10133361 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06987218 0,10127257 ! startle response GO:0001964 28 16 0,000 0,06987218 0,1012116 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06987218 0,1011507 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06987218 0,10108987 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06987218 0,10102912 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06987218 0,10096845 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06987218 0,10090784 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06987218 0,10084731 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06987218 0,10078685 ! response to osmotic stress GO:0006970 25 16 0,000 0,06987218 0,10072646 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06987218 0,10066614 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06987218 0,1006059 ! fructose metabolic process GO:0006000 25 16 0,000 0,06987218 0,10054573 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06987218 0,10048563 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06987218 0,1004256 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06987218 0,10036565 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06987218 0,10030576 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06987218 0,10024595 ! axon cargo transport GO:0008088 43 16 0,000 0,06987218 0,10018621 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06987218 0,10012654 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06987218 0,10006694 ! DNA replication initiation GO:0006270 27 16 0,000 0,06987218 0,10000741 ! neuron recognition GO:0008038 35 16 0,000 0,06987218 0,09994796 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06987218 0,09988857 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06987218 0,09982925 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06987218 0,09977001 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06987218 0,09971083 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06987218 0,09965173 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06987218 0,09959269 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06987218 0,09953372 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06987218 0,09947483 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06987218 0,099416 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06987218 0,09935725 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06987218 0,09929856 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06987218 0,09923994 ! defense response to virus GO:0051607 37 16 0,000 0,06987218 0,09918139 ! protein ubiquitination GO:0016567 217 97 1,000 0,07140936 0,10130361 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07407461 0,10502269 ! metencephalon development GO:0022037 30 17 0,000 0,07407461 0,10496084 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,07407461 0,10489906 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07407461 0,10483736 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07407461 0,10477573 ! signal complex assembly GO:0007172 41 17 0,000 0,07407461 0,10471417 ! endothelial cell migration GO:0043542 28 17 0,000 0,07407461 0,10465268 ! inositol metabolic process GO:0006020 28 17 0,000 0,07407461 0,10459126 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07407461 0,10452992 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07407461 0,10446865 ! glial cell development GO:0021782 27 17 0,000 0,07407461 0,10440745 ! limbic system development GO:0021761 36 17 0,000 0,07407461 0,10434632 ! adult walking behavior GO:0007628 33 17 0,000 0,07407461 0,10428526 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07407461 0,10422428 ! heart looping GO:0001947 30 17 0,000 0,07407461 0,10416336 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07407461 0,10410252 ! myoblast differentiation GO:0045445 45 17 0,000 0,07407461 0,10404175 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07407461 0,10398104 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07407461 0,10392041 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07407461 0,10385985 ! glycine metabolic process GO:0006544 28 17 0,000 0,07407461 0,10379937 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07407461 0,10373895 ! NAD metabolic process GO:0019674 29 17 0,000 0,07407461 0,1036786 ! membrane budding GO:0006900 37 17 0,000 0,07407461 0,10361832 ! DNA integration GO:0015074 29 17 0,000 0,07407461 0,10355811 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07407461 0,10349797 ! regulation of protein binding GO:0043393 33 17 0,000 0,07407461 0,10343791 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07407461 0,10337791 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07407461 0,10331798 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07407461 0,10325812 ! genitalia development GO:0048806 30 17 0,000 0,07407461 0,10319833 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07407461 0,10313861 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07407461 0,10307895 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07407461 0,10301937 ! steroid catabolic process GO:0006706 31 17 0,000 0,07407461 0,10295986 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07407461 0,10290041 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07407461 0,10284103 ! gas transport GO:0015669 25 17 0,000 0,07407461 0,10278172 ! organic cation transport GO:0015695 31 17 0,000 0,07407461 0,10272248 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07407461 0,10266331 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07407461 0,10260421 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07407461 0,10254517 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07407461 0,10248621 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07407461 0,1024273 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07825819 0,10815004 ! neuron maturation GO:0042551 42 18 0,000 0,07825819 0,10808795 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07825819 0,10802594 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,07825819 0,107964 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07825819 0,10790213 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07825819 0,10784033 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07825819 0,1077786 ! memory GO:0007613 31 18 0,000 0,07825819 0,10771694 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07825819 0,10765535 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07825819 0,10759384 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07825819 0,10753239 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07825819 0,10747101 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07825819 0,1074097 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07825819 0,10734847 ! response to retinoic acid GO:0032526 26 18 0,000 0,07825819 0,1072873 ! response to fungus GO:0009620 21 18 0,000 0,07825819 0,1072262 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07825819 0,10716517 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07825819 0,10710422 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07825819 0,10704333 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07825819 0,10698251 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07825819 0,10692176 ! vitamin transport GO:0051180 27 18 0,000 0,07825819 0,10686107 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07825819 0,10680046 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07825819 0,10673992 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07825819 0,10667944 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07825819 0,10661903 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07825819 0,10655869 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07825819 0,10649842 ! nerve development GO:0021675 28 18 0,000 0,07825819 0,10643822 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07825819 0,10637809 ! protein secretion GO:0009306 39 19 0,000 0,08242301 0,11197615 ! positive regulation of translation GO:0045727 30 19 0,000 0,08242301 0,11191296 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08242301 0,11184984 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08242301 0,11178679 ! skin development GO:0043588 36 19 0,000 0,08242301 0,11172381 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08242301 0,1116609 ! lipid phosphorylation GO:0046834 35 19 0,000 0,08242301 0,11159807 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08242301 0,1115353 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08242301 0,11147261 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08242301 0,11140998 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08242301 0,11134743 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08242301 0,11128494 ! cerebral cortex development GO:0021987 36 19 0,000 0,08242301 0,11122253 ! pigmentation during development GO:0048066 41 19 0,000 0,08242301 0,11116018 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08242301 0,11109791 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,08242301 0,1110357 ! heme metabolic process GO:0042168 36 19 0,000 0,08242301 0,11097357 ! neuromuscular junction development GO:0007528 34 19 0,000 0,08242301 0,1109115 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08242301 0,11084951 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08242301 0,11078758 ! peptide cross-linking GO:0018149 37 19 0,000 0,08242301 0,11072572 ! protein export from nucleus GO:0006611 36 19 0,000 0,08242301 0,11066393 ! heart process GO:0003015 30 19 0,000 0,08242301 0,11060221 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08242301 0,11054056 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08242301 0,11047898 ! visual learning GO:0008542 36 19 0,000 0,08242301 0,11041746 ! cellular pigmentation GO:0033059 36 19 0,000 0,08242301 0,11035602 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08242301 0,11029464 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08242301 0,11023333 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,08242301 0,11017209 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08242301 0,11011092 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08242301 0,11004981 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08242301 0,10998878 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08242301 0,10992781 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08242301 0,10986691 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08242301 0,10980607 ! cilium assembly GO:0042384 37 19 0,000 0,08242301 0,1097453 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08656915 0,11520209 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08656915 0,11513841 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08656915 0,11507479 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08656915 0,11501125 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08656915 0,11494778 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08656915 0,11488438 ! response to vitamin GO:0033273 31 20 0,000 0,08656915 0,11482104 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08656915 0,11475778 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08656915 0,11469459 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08656915 0,11463147 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08656915 0,11456841 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08656915 0,11450543 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08656915 0,11444251 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08656915 0,11437967 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08656915 0,11431689 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08656915 0,11425418 GO:0032392|DNA geometric change, ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08656915 0,11419154 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08656915 0,11412897 ! stem cell differentiation GO:0048863 53 20 0,000 0,08656915 0,11406647 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08656915 0,11400404 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08656915 0,11394167 ! sensory perception of pain GO:0019233 30 20 0,000 0,08656915 0,11387937 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08656915 0,11381714 ! diencephalon development GO:0021536 34 20 0,000 0,08656915 0,11375498 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08656915 0,11369289 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08656915 0,11363086 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08656915 0,11356891 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08656915 0,11350702 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08656915 0,11344519 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08656915 0,11338344 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08656915 0,11332175 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08656915 0,11326013 ! regulation of glucose import GO:0046324 29 20 0,000 0,08656915 0,11319857 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08656915 0,11313709 ! actin filament-based movement GO:0030048 43 20 0,000 0,08656915 0,11307566 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08656915 0,11301431 ! negative regulation of translation GO:0017148 29 20 0,000 0,08656915 0,11295302 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,08656915 0,1128918 ! regulation of cell killing GO:0031341 42 21 0,000 0,09069669 0,11821031 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,09069669 0,11814631 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09069669 0,11808238 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09069669 0,11801852 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09069669 0,11795472 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,09069669 0,117891 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09069669 0,11782734 ! axis specification GO:0009798 38 21 0,000 0,09069669 0,11776375 ! ovarian follicle development GO:0001541 35 21 0,000 0,09069669 0,11770024 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09069669 0,11763679 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09069669 0,1175734 ! cell aging GO:0007569 44 21 0,000 0,09069669 0,11751009 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09069669 0,11744684 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09069669 0,11738367 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,09069669 0,11732056 ! cytolysis GO:0019835 24 21 0,000 0,09069669 0,11725752 ! vasodilation GO:0042311 39 21 0,000 0,09069669 0,11719454 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09069669 0,11713164 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09069669 0,1170688 ! oogenesis GO:0048477 36 21 0,000 0,09069669 0,11700603 ! DNA modification GO:0006304 34 21 0,000 0,09069669 0,11694332 ! collagen fibril organization GO:0030199 59 21 0,000 0,09069669 0,11688068 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,09069669 0,11681811 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,09069669 0,11675561 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,09069669 0,11669318 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,09069669 0,11663081 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09069669 0,1165685 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09069669 0,11650627 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,09069669 0,1164441 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09069669 0,11638199 ! collagen catabolic process GO:0030574 28 21 0,000 0,09069669 0,11631996 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09069669 0,11625799 ! gut development GO:0048565 39 21 0,000 0,09069669 0,11619608 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09480572 0,12139572 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09480572 0,12133115 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09480572 0,12126664 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09480572 0,12120221 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09480572 0,12113784 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09480572 0,12107354 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09480572 0,12100931 ! regeneration GO:0031099 41 22 0,000 0,09480572 0,12094515 ! keratinization GO:0031424 28 22 0,000 0,09480572 0,12088106 ! sensory perception of taste GO:0050909 28 22 0,000 0,09480572 0,12081703 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,09480572 0,12075307 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09480572 0,12068918 ! vacuolar transport GO:0007034 36 22 0,000 0,09480572 0,12062536 ! lysosome organization GO:0007040 41 22 0,000 0,09480572 0,1205616 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09480572 0,12049792 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09480572 0,1204343 ! fucose metabolic process GO:0006004 39 22 0,000 0,09480572 0,12037074 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09480572 0,12030725 ! ureteric bud development GO:0001657 43 22 0,000 0,09480572 0,12024383 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09480572 0,12018048 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09480572 0,1201172 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09480572 0,12005398 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09480572 0,11999082 ! sarcomere organization GO:0045214 30 22 0,000 0,09480572 0,11992774 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09480572 0,11986472 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09480572 0,11980176 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09480572 0,11973887 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,09480572 0,11967605 ! protein stabilization GO:0050821 39 22 0,000 0,09480572 0,1196133 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09889631 0,12470887 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09889631 0,12464354 ! gluconeogenesis GO:0006094 33 23 0,000 0,09889631 0,12457828 ! viral genome replication GO:0019079 41 23 0,000 0,09889631 0,12451309 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09889631 0,12444797 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09889631 0,12438292 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09889631 0,12431793 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09889631 0,12425301 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09889631 0,12418816 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09889631 0,12412338 ! visual behavior GO:0007632 42 23 0,000 0,09889631 0,12405867 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,09889631 0,12399402 ! response to ethanol GO:0045471 46 23 0,000 0,09889631 0,12392944 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09889631 0,12386493 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09889631 0,12380048 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09889631 0,1237361 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09889631 0,12367179 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09889631 0,12360754 ! sex determination GO:0007530 47 23 0,000 0,09889631 0,12354337 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,09889631 0,12347925 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09889631 0,12341521 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09889631 0,12335123 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09889631 0,12328732 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09889631 0,12322347 ! fatty acid transport GO:0015908 44 23 0,000 0,09889631 0,12315969 ! platelet activation GO:0030168 37 23 0,000 0,09889631 0,12309598 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09889631 0,12303233 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09889631 0,12296875 ! cell-cell recognition GO:0009988 25 23 0,000 0,09889631 0,12290523 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09889631 0,12284178 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09889631 0,12277839 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,09889631 0,12271507 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09889631 0,12265182 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09889631 0,12258863 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,10296855 0,12757072 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10296855 0,12750507 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10296855 0,12743948 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10296855 0,12737395 ! spinal cord development GO:0021510 47 24 0,000 0,10296855 0,1273085 ! vacuole organization GO:0007033 43 24 0,000 0,10296855 0,12724311 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10296855 0,12717779 ! digestive system process GO:0022600 39 24 0,000 0,10296855 0,12711254 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10296855 0,12704735 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10296855 0,12698224 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10296855 0,12691718 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,10296855 0,1268522 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10296855 0,12678728 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10296855 0,12672243 ! pallium development GO:0021543 49 24 0,000 0,10296855 0,12665764 ! pentose metabolic process GO:0019321 35 24 0,000 0,10296855 0,12659292 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,10296855 0,12652826 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10296855 0,12646368 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10296855 0,12639915 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10296855 0,1263347 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10296855 0,12627031 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10296855 0,12620598 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10296855 0,12614172 ! regulation of amine transport GO:0051952 40 24 0,000 0,10296855 0,12607753 ! protein tetramerization GO:0051262 52 24 0,000 0,10296855 0,1260134 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10702253 0,13090809 ! myelination GO:0042552 45 25 0,000 0,10702253 0,13084157 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10702253 0,13077512 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10702253 0,13070873 ! phototransduction GO:0007602 33 25 0,000 0,10702253 0,13064242 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10702253 0,13057617 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,10702253 0,13050999 ! sperm motility GO:0030317 31 25 0,000 0,10702253 0,13044387 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,10702253 0,13037783 ! receptor metabolic process GO:0043112 46 25 0,000 0,10702253 0,13031185 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10702253 0,13024593 ! negative regulation of cell development GO:0010721 73 25 0,000 0,10702253 0,13018008 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10702253 0,1301143 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10702253 0,13004859 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10702253 0,12998294 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10702253 0,12991736 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10702253 0,12985184 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10702253 0,12978639 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10702253 0,12972101 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10702253 0,12965569 ! telomere organization GO:0032200 43 25 0,000 0,10702253 0,12959044 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10702253 0,12952525 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10702253 0,12946013 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11105832 0,13427453 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,11105832 0,13420709 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,11105832 0,13413972 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11105832 0,13407241 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11105832 0,13400517 ! molting cycle process GO:0022404 50 26 0,000 0,11105832 0,133938 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,11105832 0,1338709 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11105832 0,13380386 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11105832 0,13373689 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11105832 0,13366999 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,11105832 0,13360316 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,11105832 0,13353639 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,11105832 0,13346969 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,11105832 0,13340305 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,11105832 0,13333648 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11105832 0,13326998 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11105832 0,13320355 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11105832 0,13313718 ! blastocyst development GO:0001824 49 26 0,000 0,11105832 0,13307087 ! leukocyte proliferation GO:0070661 52 26 0,000 0,11105832 0,13300464 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11105832 0,13293846 ! neuron fate commitment GO:0048663 48 27 0,000 0,115076 0,13767919 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,115076 0,13761076 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,115076 0,1375424 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,115076 0,13747411 ! fat cell differentiation GO:0045444 50 27 0,000 0,115076 0,13740588 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,115076 0,13733773 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,115076 0,13726964 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,115076 0,13720161 ! autophagy GO:0006914 41 27 0,000 0,115076 0,13713366 ! male gonad development GO:0008584 44 27 0,000 0,115076 0,13706577 ! response to toxin GO:0009636 47 27 0,000 0,115076 0,13699795 ! primary neural tube formation GO:0014020 51 27 0,000 0,115076 0,1369302 ! base-excision repair GO:0006284 41 27 0,000 0,115076 0,13686251 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,115076 0,13679489 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,115076 0,13672734 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,115076 0,13665985 ! circadian rhythm GO:0007623 50 28 0,000 0,11907566 0,14133993 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11907566 0,14127023 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,11907566 0,14120061 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11907566 0,14113105 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,11907566 0,14106156 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,11907566 0,14099214 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11907566 0,14092279 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,11907566 0,1408535 ! synaptogenesis GO:0007416 42 28 0,000 0,11907566 0,14078429 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,11907566 0,14071514 ! lipid oxidation GO:0034440 43 28 0,000 0,11907566 0,14064606 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11907566 0,14057705 ! translational initiation GO:0006413 65 29 0,000 0,12305737 0,14520649 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12305737 0,14513531 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12305737 0,1450642 ! catechol metabolic process GO:0009712 54 29 0,000 0,12305737 0,14499316 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12305737 0,14492219 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,12305737 0,14485128 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12305737 0,14478045 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12305737 0,14470969 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,12305737 0,144639 ! cell fate determination GO:0001709 60 29 0,000 0,12305737 0,14456837 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12305737 0,14449782 ! detection of light stimulus GO:0009583 38 29 0,000 0,12305737 0,14442733 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,12305737 0,14435691 ! tissue homeostasis GO:0001894 48 29 0,000 0,12305737 0,14428656 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,12702121 0,14886169 ! zinc ion transport GO:0006829 45 30 0,000 0,12702121 0,14878921 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12702121 0,14871681 ! acute-phase response GO:0006953 49 30 0,000 0,12702121 0,14864447 ! myofibril assembly GO:0030239 47 30 0,000 0,12702121 0,14857221 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12702121 0,14850002 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,12702121 0,1484279 ! phospholipid transport GO:0015914 51 30 0,000 0,12702121 0,14835584 ! ensheathment of neurons GO:0007272 57 30 0,000 0,12702121 0,14828386 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12702121 0,14821195 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12702121 0,14814011 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12702121 0,14806833 ! eye morphogenesis GO:0048592 60 30 0,000 0,12702121 0,14799663 ! response to heat GO:0009408 50 30 0,000 0,12702121 0,147925 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,13096727 0,15244667 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,13096727 0,15237295 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,13096727 0,1522993 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,13096727 0,15222573 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,13096727 0,15215223 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,13096727 0,15207879 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,13096727 0,15200543 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,13096727 0,15193214 ! ovulation cycle process GO:0022602 49 31 0,000 0,13096727 0,15185892 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,13096727 0,15178577 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,13096727 0,15171269 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,13096727 0,15163968 ! natural killer cell activation GO:0030101 45 31 0,000 0,13096727 0,15156674 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,13096727 0,15149388 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,13096727 0,15142108 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,13096727 0,15134835 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,13096727 0,15127569 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,13489563 0,15573843 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13489563 0,15566373 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13489563 0,15558911 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,13489563 0,15551456 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13489563 0,15544008 ! spliceosome assembly GO:0000245 67 32 0,000 0,13489563 0,15536567 ! spindle organization GO:0007051 46 32 0,000 0,13489563 0,15529133 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13489563 0,15521706 ! metanephros development GO:0001656 74 32 0,000 0,13489563 0,15514287 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13489563 0,15506874 ! response to ionizing radiation GO:0010212 65 32 0,000 0,13489563 0,15499469 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,13489563 0,15492071 ! muscle cell development GO:0055001 49 32 0,000 0,13489563 0,15484679 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,13489563 0,15477295 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13489563 0,15469918 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,13489563 0,15462548 ! ovulation cycle GO:0042698 51 32 0,000 0,13489563 0,15455185 ! peripheral nervous system development GO:0007422 64 32 0,000 0,13489563 0,15447829 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,13489563 0,1544048 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13489563 0,15433137 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,13489563 0,15425802 ! gene silencing GO:0016458 65 32 0,000 0,13489563 0,15418474 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,13880635 0,15857934 ! post-embryonic development GO:0009791 69 33 0,000 0,13880635 0,15850408 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,13880635 0,15842888 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13880635 0,15835376 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13880635 0,15827871 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13880635 0,15820374 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13880635 0,15812883 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13880635 0,15805399 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,13880635 0,15797923 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13880635 0,15790453 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,14269953 0,16225665 ! glial cell differentiation GO:0010001 63 34 0,000 0,14269953 0,16218001 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,14269953 0,16210343 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,14269953 0,16202693 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,14269953 0,16195051 ! mismatch repair GO:0006298 46 34 0,000 0,14269953 0,16187415 ! spermatid development GO:0007286 63 34 0,000 0,14269953 0,16179787 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,14269953 0,16172165 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,14269953 0,16164551 ! placenta development GO:0001890 53 34 0,000 0,14269953 0,16156945 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,14657524 0,1658796 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,14657524 0,16580161 ! odontogenesis GO:0042476 66 35 0,000 0,14657524 0,16572369 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14657524 0,16564585 ! female gonad development GO:0008585 58 35 0,000 0,14657524 0,16556808 ! telencephalon development GO:0021537 68 35 0,000 0,14657524 0,16549039 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,14657524 0,16541277 ! cytokine production GO:0001816 59 35 0,000 0,14657524 0,16533522 ! neural tube formation GO:0001841 67 35 0,000 0,14657524 0,16525774 ! vesicle localization GO:0051648 64 35 0,000 0,14657524 0,16518034 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,15043355 0,16944903 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,15043355 0,16936973 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,15043355 0,16929051 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,15043355 0,16921137 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,15043355 0,1691323 ! positive regulation of cell development GO:0010720 80 36 0,000 0,15043355 0,1690533 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,15043355 0,16897438 ! regulation of proteolysis GO:0030162 72 36 0,000 0,15043355 0,16889553 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,15043355 0,16881675 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,15043355 0,16873805 ! aerobic respiration GO:0009060 55 36 0,000 0,15043355 0,16865942 ! embryonic organ development GO:0048568 57 36 0,000 0,15043355 0,16858087 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,15043355 0,16850238 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15427455 0,17272432 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,15427455 0,17264398 ! meiosis I GO:0007127 65 37 0,000 0,15427455 0,17256372 ! sister chromatid segregation GO:0000819 58 37 0,000 0,15427455 0,17248353 ! actomyosin structure organization GO:0031032 62 37 0,000 0,15427455 0,17240342 ! organic anion transport GO:0015711 68 37 0,000 0,15427455 0,17232338 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15427455 0,17224342 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15427455 0,17216352 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,15427455 0,17208371 ! spermatid differentiation GO:0048515 66 37 0,000 0,15427455 0,17200397 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,15427455 0,1719243 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,15809831 0,17610395 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,15809831 0,17602245 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,15809831 0,17594104 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,15809831 0,1758597 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,15809831 0,17577843 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,15809831 0,17569724 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 0,000 0,15809831 0,17561612 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,15809831 0,17553508 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,15809831 0,17545412 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,15809831 0,17537322 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,15809831 0,17529241 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1619049 0,17943031 ! learning GO:0007612 77 39 0,000 0,1619049 0,1793477 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,1619049 0,17926516 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1619049 0,1791827 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1619049 0,17910032 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,1619049 0,17901801 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1619049 0,17893578 ! RNA modification GO:0009451 57 39 0,000 0,1619049 0,17885362 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1619049 0,17877154 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,16569441 0,18287191 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,16569441 0,18278806 ! feeding behavior GO:0007631 59 40 0,000 0,16569441 0,18270429 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,16569441 0,1826206 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,16569441 0,18253698 ! maintenance of protein location GO:0045185 91 40 0,000 0,16569441 0,18245344 ! cytokinesis GO:0000910 72 40 0,000 0,16569441 0,18236997 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,16946692 0,18643685 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,16946692 0,18635165 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,16946692 0,18626652 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,16946692 0,18618146 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,16946692 0,18609649 ! female gamete generation GO:0007292 61 41 0,000 0,16946692 0,18601159 ! polyol metabolic process GO:0019751 66 41 0,000 0,16946692 0,18592677 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,17322249 0,18996048 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,17322249 0,18987394 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,17322249 0,18978748 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,17322249 0,18970109 ! neuron migration GO:0001764 79 42 0,000 0,17322249 0,18961479 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,1769612 0,19361921 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,1769612 0,1935312 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,1769612 0,19344327 ! neural tube development GO:0021915 77 43 0,000 0,1769612 0,19335542 ! striated muscle contraction GO:0006941 77 43 0,000 0,1769612 0,19326765 ! phagocytosis GO:0006909 90 43 0,000 0,1769612 0,19317996 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,1769612 0,19309235 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,18068313 0,19706419 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,18068313 0,1969749 ! male sex differentiation GO:0046661 76 44 0,000 0,18068313 0,19688569 ! double-strand break repair GO:0006302 81 44 0,000 0,18068313 0,19679656 ! biopolymer methylation GO:0043414 84 44 0,000 0,18068313 0,19670751 ! B cell differentiation GO:0030183 107 44 0,000 0,18068313 0,19661854 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,18068313 0,19652966 ! developmental growth GO:0048589 82 44 0,000 0,18068313 0,19644085 ! glycolysis GO:0006096 65 45 0,000 0,18438835 0,20037866 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,18438835 0,2002882 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,18438835 0,20019782 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18438835 0,20010751 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,18438835 0,2000173 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,18807693 0,20392659 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,18807693 0,20383473 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,18807693 0,20374295 ! response to insulin stimulus GO:0032868 95 46 0,000 0,18807693 0,20365126 ! positive regulation of defense response GO:0031349 76 47 0,000 0,19174896 0,20753396 ! response to calcium ion GO:0051592 81 47 0,000 0,19174896 0,20744065 ! endosome transport GO:0016197 108 47 0,000 0,19174896 0,20734742 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,19174896 0,20725427 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,19174896 0,2071612 ! JNK cascade GO:0007254 91 47 0,000 0,19174896 0,20706822 ! methylation GO:0032259 90 47 0,000 0,19174896 0,20697532 ! mitochondrial transport GO:0006839 82 48 0,000 0,1954045 0,21082656 ! Notch signaling pathway GO:0007219 96 48 0,000 0,1954045 0,21073206 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,1954045 0,21063765 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,1954045 0,21054332 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,1954045 0,21044907 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,1954045 0,21035491 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,19904363 0,21417664 ! regulation of action potential GO:0001508 95 49 0,000 0,19904363 0,2140809 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,19904363 0,21398524 ! regulation of ion transport GO:0043269 77 49 0,000 0,19904363 0,21388967 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,19904363 0,21379419 ! response to temperature stimulus GO:0009266 76 49 0,000 0,19904363 0,21369879 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,19904363 0,21360347 ! endocrine system development GO:0035270 104 49 0,000 0,19904363 0,21350824 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,19904363 0,21341309 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,19904363 0,21331803 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,19904363 0,21322305 ! neuromuscular process GO:0050905 99 50 0,000 0,20266642 0,2170073 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,20266642 0,21691077 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,20266642 0,21681432 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,20627295 0,22057454 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,20627295 0,22047655 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,20627295 0,22037865 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,20627295 0,22028083 ! chromatin remodeling GO:0006338 109 51 0,000 0,20627295 0,2201831 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,20627295 0,22008546 ! regulation of cell shape GO:0008360 125 51 0,000 0,20627295 0,2199879 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,20627295 0,21989043 ! positive regulation of growth GO:0045927 90 52 0,000 0,20986328 0,22361871 ! amino acid activation GO:0043038 92 52 0,000 0,20986328 0,22351972 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,20986328 0,22342082 ! RNA catabolic process GO:0006401 93 53 0,000 0,21343749 0,22712543 ! regulation of translational initiation GO:0006446 82 53 0,000 0,21343749 0,22702502 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,21343749 0,2269247 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,21343749 0,22682447 ! cell maturation GO:0048469 100 53 0,000 0,21343749 0,22672432 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,21343749 0,22662427 ! cell recognition GO:0008037 85 54 0,000 0,21699565 0,23030063 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,21699565 0,23019908 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,21699565 0,23009763 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,21699565 0,22999627 ! chloride transport GO:0006821 90 55 0,000 0,22053783 0,23364774 ! glucose catabolic process GO:0006007 82 55 0,000 0,22053783 0,2335449 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,22053783 0,23344215 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,22053783 0,23333949 ! heart morphogenesis GO:0003007 97 55 0,000 0,22053783 0,23323693 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,22053783 0,23313445 ! RNA elongation GO:0006354 79 55 0,000 0,22053783 0,23303206 ! nuclear export GO:0051168 97 55 0,000 0,22053783 0,23292977 ! sensory perception of smell GO:0007608 80 56 0,000 0,2240641 0,23655034 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,2240641 0,23644659 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,2240641 0,23634293 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,2240641 0,23623936 ! proton transport GO:0015992 94 56 0,000 0,2240641 0,23613589 ! muscle fiber development GO:0048747 112 57 0,000 0,22757454 0,23973045 ! lipid modification GO:0030258 97 57 0,000 0,22757454 0,23962553 ! hydrogen transport GO:0006818 97 58 0,000 0,23106921 0,24319883 ! adult behavior GO:0030534 99 58 0,000 0,23106921 0,24309249 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,23454819 0,24664464 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,23454819 0,24653689 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,23454819 0,24642923 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,23801154 0,24995887 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,23801154 0,24984981 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,23801154 0,24974085 ! camera-type eye development GO:0043010 116 60 0,000 0,23801154 0,24963198 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,23801154 0,24952321 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,24145934 0,25302751 ! tRNA processing GO:0008033 89 61 0,000 0,24145934 0,25291736 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,24145934 0,2528073 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,24145934 0,25269733 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,24489165 0,25617796 ! gonad development GO:0008406 98 62 0,000 0,24489165 0,25606663 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,24830854 0,25952665 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,24830854 0,25941396 ! cell redox homeostasis GO:0045454 102 64 0,000 0,25171009 0,2628535 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,25171009 0,26273947 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,25171009 0,26262553 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,25171009 0,26251169 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,25509635 0,265928 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,25509635 0,26581283 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,25509635 0,26569776 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,25509635 0,26558279 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,25846741 0,26897603 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,25846741 0,26885974 ! extracellular matrix organization GO:0030198 133 66 0,000 0,25846741 0,26874355 ! secondary metabolic process GO:0019748 116 66 0,000 0,25846741 0,26862746 ! developmental maturation GO:0021700 116 66 0,000 0,25846741 0,26851148 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,26182332 0,27188041 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,26182332 0,27176311 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,26182332 0,27164592 ! hexose catabolic process GO:0019320 104 67 0,000 0,26182332 0,27152884 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,26182332 0,27141185 ! adaptive immune response GO:0002250 119 67 0,000 0,26182332 0,27129496 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,26182332 0,27117817 ! amino acid transport GO:0006865 125 68 0,000 0,26516415 0,2745202 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,26516415 0,27440213 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,26516415 0,27428415 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,26848997 0,27760502 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,26848997 0,27748577 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,26848997 0,27736663 ! antigen processing and presentation GO:0019882 104 69 0,000 0,26848997 0,27724759 ! appendage morphogenesis GO:0035107 135 70 0,000 0,27180085 0,28054606 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,27509686 0,28382635 ! reproductive structure development GO:0048608 113 71 0,000 0,27509686 0,28370469 ! appendage development GO:0048736 136 71 0,000 0,27509686 0,28358314 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,27509686 0,28346169 ! regulation of immune effector process GO:0002697 137 71 0,000 0,27509686 0,28334034 ! acute inflammatory response GO:0002526 113 72 0,000 0,27837806 0,28659718 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,27837806 0,2864746 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,28164451 0,28971214 ! axon guidance GO:0007411 139 73 0,000 0,28164451 0,28958833 ! fertilization GO:0009566 90 73 0,000 0,28164451 0,28946463 ! neurotransmitter transport GO:0006836 123 74 0,000 0,28489628 0,29268167 ! meiosis GO:0007126 121 74 0,000 0,28489628 0,29255675 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,28489628 0,29243194 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,28489628 0,29230723 ! eye development GO:0001654 143 74 0,000 0,28489628 0,29218263 ! meiotic cell cycle GO:0051321 122 75 0,000 0,28813345 0,29537668 ! rhythmic process GO:0048511 128 75 0,000 0,28813345 0,29525088 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,29135607 0,29842601 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,29135607 0,29829902 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,29135607 0,29817214 ! regulation of catabolic process GO:0009894 161 76 0,000 0,29135607 0,29804536 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,29775792 0,30446475 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,29775792 0,30433541 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,30093728 0,30745439 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,30410236 0,31055614 ! response to metal ion GO:0010038 140 80 0,000 0,30410236 0,31042438 ! muscle cell differentiation GO:0042692 159 80 0,000 0,30410236 0,31029274 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,30410236 0,3101612 ! protein import into nucleus GO:0006606 158 80 0,000 0,30410236 0,31002978 ! inorganic anion transport GO:0015698 138 80 0,000 0,30410236 0,30989846 ! digestion GO:0007586 112 81 0,000 0,30725321 0,31297681 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,30725321 0,31284436 ! nuclear import GO:0051170 161 81 0,000 0,30725321 0,31271202 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,31038989 0,31577086 ! response to drug GO:0042493 143 82 0,000 0,31038989 0,3156374 ! response to nutrient GO:0007584 125 82 0,000 0,31038989 0,31550405 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,31038989 0,31537081 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,31038989 0,31523769 ! regulation of lyase activity GO:0051339 160 83 0,000 0,31351248 0,3182747 ! response to unfolded protein GO:0006986 131 85 0,000 0,31971562 0,32443517 ! nucleosome assembly GO:0006334 122 85 0,000 0,31971562 0,32429839 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,31971562 0,32416173 ! amine biosynthetic process GO:0009309 138 86 0,000 0,32279629 0,32714738 ! response to inorganic substance GO:0010035 153 86 0,000 0,32279629 0,32700963 ! chromatin assembly GO:0031497 124 86 0,000 0,32279629 0,326872 ! alcohol catabolic process GO:0046164 130 86 0,000 0,32279629 0,32673448 ! amine transport GO:0015837 155 86 0,000 0,32279629 0,32659709 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,32586311 0,32956143 ! protein localization in nucleus GO:0034504 176 87 0,000 0,32586311 0,32942296 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,32891614 0,33236969 ! cellular defense response GO:0006968 114 89 0,000 0,33195545 0,33530009 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,33195545 0,33515939 ! sex differentiation GO:0007548 145 90 0,000 0,3349811 0,33807237 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,3349811 0,33793062 ! sterol metabolic process GO:0016125 152 91 0,000 0,33799314 0,34082627 ! response to protein stimulus GO:0051789 149 91 0,000 0,33799314 0,34068349 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,33799314 0,34054083 ! regulation of defense response GO:0031347 149 92 0,000 0,34099164 0,34341812 ! nucleosome organization GO:0034728 138 92 0,000 0,34099164 0,34327443 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,34099164 0,34313086 ! vitamin metabolic process GO:0006766 139 92 0,000 0,34099164 0,34298741 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,34397665 0,34584531 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,34694825 0,34868734 ! female pregnancy GO:0007565 164 94 0,000 0,34694825 0,34854175 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,34990648 0,35136686 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,35285141 0,35417626 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,35285141 0,35402857 ! positive regulation of immune response GO:0050778 156 96 0,000 0,35285141 0,35388099 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,3557831 0,35667256 ! hormone metabolic process GO:0042445 157 97 0,000 0,3557831 0,35652401 ! response to virus GO:0009615 160 98 0,000 0,35870161 0,35929894 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,35870161 0,35914942 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,35870161 0,35900003 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,36160699 0,36175734 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,36160699 0,36160699