pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1259-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 1,053E-05 0,02421756 ! collagen catabolic process GO:0030574 25 20 2,000 1,053E-05 0,01210878 ! response to hypoxia GO:0001666 132 72 3,000 1,756E-05 0,01346191 ! response to oxygen levels GO:0070482 137 74 3,000 1,958E-05 0,01125705 ! multicellular organismal catabolic process GO:0044243 32 26 2,000 2,38E-05 0,01094755 ! collagen metabolic process GO:0032963 40 30 2,000 3,694E-05 0,01416058 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,582E-05 0,01505455 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 4,582E-05 0,01317273 GO:0045686|negative regulation of glial cell differentiation, ! negative regulation of T cell mediated immunity GO:0002710 11 5 1,000 4,582E-05 0,0117091 GO:0002707|negative regulation of lymphocyte mediated immunity, ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 4,582E-05 0,01053819 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 2,000 4,942E-05 0,01033315 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 2,000 5,911E-05 0,0113286 GO:0015986|ATP synthesis coupled proton transport, ! protein homooligomerization GO:0051260 52 35 2,000 5,911E-05 0,01045717 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 6,863E-05 0,01127542 ! response to copper ion GO:0046688 9 6 1,000 6,863E-05 0,01052372 ! gas homeostasis GO:0033483 11 6 1,000 6,863E-05 9,866E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 6,863E-05 9,286E-03 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 6,863E-05 8,77E-03 ! ion transmembrane transport GO:0034220 56 37 2,000 6,996E-05 8,469E-03 ! multicellular organismal metabolic process GO:0044236 50 39 2,000 8,204E-05 9,434E-03 ! cell growth GO:0016049 61 39 2,000 8,204E-05 8,985E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 9,595E-05 0,01003159 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 9,595E-05 9,595E-03 ! vesicle fusion GO:0006906 15 7 1,000 9,595E-05 9,196E-03 ! neuroblast proliferation GO:0007405 13 7 1,000 9,595E-05 8,828E-03 ! lymph node development GO:0048535 9 7 1,000 9,595E-05 8,488E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 1,000 9,595E-05 8,174E-03 ! ATP catabolic process GO:0006200 10 7 1,000 9,595E-05 7,882E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,101E-04 8,734E-03 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 1,000 1,278E-04 9,795E-03 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,278E-04 9,479E-03 ! regulation of gliogenesis GO:0014013 20 8 1,000 1,278E-04 9,183E-03 GO:0045685|regulation of glial cell differentiation, ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 1,278E-04 8,905E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,278E-04 8,643E-03 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 1,64E-04 0,01077991 ! substrate-bound cell migration GO:0006929 10 9 1,000 1,64E-04 0,01048046 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 1,000 1,64E-04 0,01019721 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 1,000 1,64E-04 9,929E-03 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of protein polymerization GO:0032273 15 9 1,000 1,64E-04 9,674E-03 ! localization within membrane GO:0051668 15 9 1,000 1,64E-04 9,432E-03 ! proton transport GO:0015992 75 50 2,000 1,731E-04 9,708E-03 ! hydrogen transport GO:0006818 77 51 2,000 1,836E-04 0,01005456 ! hippocampus development GO:0021766 19 10 1,000 2,048E-04 0,01095288 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 2,048E-04 0,01070395 ! purine ribonucleotide catabolic process GO:0009154 14 10 1,000 2,048E-04 0,01046609 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,048E-04 0,01023856 ! negative regulation of immune effector process GO:0002698 16 10 1,000 2,048E-04 0,01002072 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,499E-04 0,01197594 ! ribonucleotide catabolic process GO:0009261 16 11 1,000 2,499E-04 0,01173154 ! regulation of intracellular pH GO:0051453 17 11 1,000 2,499E-04 0,01149691 ! nucleoside triphosphate catabolic process GO:0009143 15 11 1,000 2,499E-04 0,01127148 ! gland morphogenesis GO:0022612 23 12 1,000 2,995E-04 0,01324747 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 3,535E-04 0,01533964 ! lipid localization GO:0010876 24 13 1,000 3,535E-04 0,01505557 GO:0019915|lipid storage, ! organelle fusion GO:0048284 28 13 1,000 3,535E-04 0,01478183 ! bone mineralization GO:0030282 15 13 1,000 3,535E-04 0,01451787 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 3,535E-04 0,01426317 ! regulation of cellular pH GO:0030641 20 13 1,000 3,535E-04 0,01401726 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 3,535E-04 0,01377967 ! protein oligomerization GO:0051259 100 65 2,000 3,771E-04 0,01445601 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 4,118E-04 0,01552788 ! limbic system development GO:0021761 25 14 1,000 4,118E-04 0,01527743 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 4,118E-04 0,01503493 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 4,745E-04 0,01705352 ! lipid phosphorylation GO:0046834 23 15 1,000 4,745E-04 0,01679116 ! regulation of vasodilation GO:0042312 24 15 1,000 4,745E-04 0,01653675 ! regulation of T cell mediated immunity GO:0002709 26 15 1,000 4,745E-04 0,01628993 ! biomineral formation GO:0031214 18 15 1,000 4,745E-04 0,01605037 ! regulation of peptidase activity GO:0052547 106 72 2,000 5,095E-04 0,01698453 ! negative regulation of immune response GO:0050777 28 16 1,000 5,416E-04 0,01779477 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 6,129E-04 0,0198561 ! inactivation of MAPK activity GO:0000188 27 17 1,000 6,129E-04 0,01958032 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 6,129E-04 0,0193121 ! oxidative phosphorylation GO:0006119 105 79 2,000 6,686E-04 0,02077992 ! ATP biosynthetic process GO:0006754 118 79 2,000 6,686E-04 0,02050285 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 6,886E-04 0,02083991 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 6,886E-04 0,02056926 ! purine nucleotide catabolic process GO:0006195 26 18 1,000 6,886E-04 0,02030555 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 6,886E-04 0,02004852 ! ossification GO:0001503 134 82 2,000 7,454E-04 0,02142952 GO:0060348|bone development, ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 7,686E-04 0,02182396 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 7,686E-04 0,02155781 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 7,686E-04 0,02129808 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 7,686E-04 0,02104453 ! hindlimb morphogenesis GO:0035137 32 20 1,000 8,528E-04 0,02307607 ! pallium development GO:0021543 38 20 1,000 8,528E-04 0,02280774 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 1,000 8,528E-04 0,02254558 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 8,562E-04 0,02237838 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 2,000 8,855E-04 0,02288293 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 2,000 9,154E-04 0,02339232 ! interphase GO:0051325 159 88 2,000 9,154E-04 0,02313526 ! regulation of cell killing GO:0031341 34 21 1,000 9,413E-04 0,02353224 ! vesicle docking GO:0048278 27 21 1,000 9,413E-04 0,0232792 ! regulation of DNA recombination GO:0000018 40 21 1,000 9,413E-04 0,02303155 ! regulation of vasoconstriction GO:0019229 31 21 1,000 9,413E-04 0,02278912 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 2,000 9,459E-04 0,02266139 ! ATP metabolic process GO:0046034 137 91 2,000 1,009E-03 0,02392043 ! vasculogenesis GO:0001570 33 22 1,000 1,034E-03 0,02426736 ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 1,034E-03 0,02402223 ! membrane depolarization GO:0051899 35 22 1,000 1,034E-03 0,02378201 ! regulation of blood coagulation GO:0030193 34 22 1,000 1,034E-03 0,02354654 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 1,131E-03 0,02550127 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 1,232E-03 0,02751175 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 1,232E-03 0,02724721 ! negative regulation of cell development GO:0010721 56 24 1,000 1,232E-03 0,02698772 GO:0050768|negative regulation of neurogenesis, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 1,232E-03 0,02673311 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 1,232E-03 0,02648327 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 2,000 1,325E-03 0,02821374 ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 1,337E-03 0,02821929 ! regulation of pH GO:0006885 36 26 1,000 1,447E-03 0,03025151 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,447E-03 0,02997898 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 1,447E-03 0,02971131 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 1,447E-03 0,02944838 ! regulation of coagulation GO:0050818 39 26 1,000 1,447E-03 0,02919006 ! membrane docking GO:0022406 39 27 1,000 1,56E-03 0,03120836 ! cholesterol homeostasis GO:0042632 46 28 1,000 1,678E-03 0,03327367 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 1,000 1,678E-03 0,03298928 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 1,678E-03 0,03270971 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 1,678E-03 0,03243483 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 1,8E-03 0,03449983 ! telencephalon development GO:0021537 52 29 1,000 1,8E-03 0,03421471 ! cholesterol transport GO:0030301 46 30 1,000 1,926E-03 0,03630839 GO:0015918|sterol transport, ! regulation of microtubule-based process GO:0032886 58 30 1,000 1,926E-03 0,0360132 ! mammary gland development GO:0030879 57 31 1,000 2,056E-03 0,03813417 ! response to mechanical stimulus GO:0009612 43 31 1,000 2,056E-03 0,0378291 ! neutral lipid metabolic process GO:0006638 41 32 1,000 2,19E-03 0,03997604 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 2,19E-03 0,03966127 ! calcium-mediated signaling GO:0019722 50 32 1,000 2,19E-03 0,03935141 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 2,19E-03 0,03904636 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 2,328E-03 0,04118934 ! lipid homeostasis GO:0055088 55 33 1,000 2,328E-03 0,04087492 ! nucleotide catabolic process GO:0009166 46 33 1,000 2,328E-03 0,04056526 ! glycerol ether metabolic process GO:0006662 44 34 1,000 2,47E-03 0,04271803 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 2,47E-03 0,04239924 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 2,616E-03 0,04457475 ! organic ether metabolic process GO:0018904 46 36 1,000 2,766E-03 0,04678571 ! tissue remodeling GO:0048771 62 36 1,000 2,766E-03 0,04644421 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 3,241E-03 0,05400933 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 1,000 3,241E-03 0,05362078 ! T cell differentiation GO:0030217 65 40 1,000 3,406E-03 0,05596319 ! positive regulation of protein transport GO:0051222 55 40 1,000 3,406E-03 0,05556629 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 3,576E-03 0,05792522 ! regulation of T cell differentiation GO:0045580 59 41 1,000 3,576E-03 0,05752015 ! mitochondrial transport GO:0006839 60 42 1,000 3,75E-03 0,05989481 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 3,75E-03 0,05948174 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 3,75E-03 0,05907433 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 3,927E-03 0,06145049 ! vesicle organization GO:0016050 79 43 1,000 3,927E-03 0,06103528 ! response to insulin stimulus GO:0032868 63 43 1,000 3,927E-03 0,06062565 ! positive regulation of cell cycle GO:0045787 77 45 1,000 4,294E-03 0,06584335 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 4,294E-03 0,0654073 ! regulation of adaptive immune response GO:0002819 72 46 1,000 4,483E-03 0,06783775 ! response to UV GO:0009411 75 46 1,000 4,483E-03 0,06739436 ! response to estrogen stimulus GO:0043627 74 47 1,000 4,676E-03 0,06983713 ! negative regulation of immune system process GO:0002683 73 47 1,000 4,676E-03 0,06938657 ! regulation of protein polymerization GO:0032271 71 47 1,000 4,676E-03 0,06894178 ! regulation of muscle contraction GO:0006937 69 48 1,000 4,873E-03 0,07138347 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 4,873E-03 0,07093168 ! regulation of intracellular transport GO:0032386 78 49 1,000 5,073E-03 0,07338466 ! heterocycle catabolic process GO:0046700 72 49 1,000 5,073E-03 0,07292601 ! cartilage development GO:0051216 70 49 1,000 5,073E-03 0,07247305 ! membrane fusion GO:0006944 80 50 1,000 5,277E-03 0,07492438 ! lipid modification GO:0030258 73 50 1,000 5,277E-03 0,07446472 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 5,485E-03 0,07692641 ! activation of phospholipase C activity GO:0007202 87 51 1,000 5,485E-03 0,07646019 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 1,000 5,485E-03 0,07599959 ! positive regulation of organelle organization GO:0010638 82 51 1,000 5,485E-03 0,0755445 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 5,697E-03 0,07799208 ! regulation of protein complex assembly GO:0043254 81 54 1,000 6,131E-03 0,08344181 ! regulation of phospholipase activity GO:0010517 90 54 1,000 6,131E-03 0,08295098 ! positive regulation of lipase activity GO:0060193 90 54 1,000 6,131E-03 0,08246588 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 6,58E-03 0,08799092 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 6,58E-03 0,08748231 ! positive regulation of cell motion GO:0051272 99 56 1,000 6,58E-03 0,08697953 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 6,81E-03 0,08950514 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 6,81E-03 0,08899659 ! developmental maturation GO:0021700 75 57 1,000 6,81E-03 0,08849378 ! negative regulation of kinase activity GO:0033673 100 58 1,000 7,044E-03 0,09101513 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 7,522E-03 0,0966488 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 7,522E-03 0,09611186 GO:0035113|embryonic appendage morphogenesis, ! homeostasis of number of cells GO:0048872 84 61 1,000 7,766E-03 0,09868623 ! extracellular matrix organization GO:0030198 103 61 1,000 7,766E-03 0,098144 ! negative regulation of transferase activity GO:0051348 105 61 1,000 7,766E-03 0,0976077 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 8,266E-03 0,10332 ! regulation of lipase activity GO:0060191 109 63 1,000 8,266E-03 0,10276152 ! appendage morphogenesis GO:0035107 93 64 1,000 8,521E-03 0,1053624 GO:0035108|limb morphogenesis, ! regulation of caspase activity GO:0043281 97 65 1,000 8,779E-03 0,10797867 ! appendage development GO:0048736 94 65 1,000 8,779E-03 0,10740432 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 8,779E-03 0,10683604 ! positive regulation of T cell activation GO:0050870 94 65 1,000 8,779E-03 0,10627375 ! regulation of immune effector process GO:0002697 101 66 1,000 9,041E-03 0,10887256 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 9,307E-03 0,111486 ! regulation of neuron differentiation GO:0045664 107 67 1,000 9,307E-03 0,11090836 ! response to metal ion GO:0010038 103 70 1,000 0,01012389 0,12002555 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,01012389 0,11941003 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,01040317 0,12207796 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,01068584 0,12475854 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01082241 0,12571485 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01082241 0,12508312 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01082241 0,1244577 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01082241 0,12383851 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01082241 0,12322545 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01082241 0,12261843 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01082241 0,12201736 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01082241 0,12142215 ! sleep GO:0030431 11 5 0,000 0,01082241 0,12083272 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01082241 0,12024899 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01082241 0,11967087 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01082241 0,11909828 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01082241 0,11853115 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01082241 0,11796939 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01082241 0,11741293 ! tongue development GO:0043586 6 5 0,000 0,01082241 0,11686169 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01082241 0,11631561 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01082241 0,11577461 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01082241 0,11523861 ! cobalt ion transport GO:0006824 9 5 0,000 0,01082241 0,11470756 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01082241 0,11418138 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01082241 0,11366 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01082241 0,11314337 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01082241 0,11263141 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01082241 0,11212406 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01082241 0,11162126 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01082241 0,11112295 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01082241 0,11062907 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01082241 0,11013956 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01082241 0,10965436 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01082241 0,10917342 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01082241 0,10869668 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01082241 0,10822409 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01082241 0,10775559 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01082241 0,10729112 ! malate metabolic process GO:0006108 7 5 0,000 0,01082241 0,10683065 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01082241 0,1063741 ! behavioral response to pain GO:0048266 7 5 0,000 0,01082241 0,10592145 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01082241 0,10547263 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01082241 0,1050276 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01082241 0,1045863 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01082241 0,10414871 ! mating behavior GO:0007617 6 5 0,000 0,01082241 0,10371475 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01082241 0,1032844 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01082241 0,10285761 ! rhythmic behavior GO:0007622 12 5 0,000 0,01082241 0,10243432 ! copulation GO:0007620 7 5 0,000 0,01082241 0,10201451 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01082241 0,10159812 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01082241 0,10118512 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01082241 0,10077547 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01082241 0,10036912 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01082241 0,09996603 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01082241 0,09956616 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01082241 0,09916948 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01082241 0,09877595 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01082241 0,09838554 ! response to protozoan GO:0001562 9 5 0,000 0,01082241 0,09799819 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01082241 0,09761388 ! lymph vessel development GO:0001945 7 5 0,000 0,01082241 0,09723258 ! endochondral ossification GO:0001958 12 5 0,000 0,01082241 0,09685424 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01082241 0,09647884 ! parathyroid gland development GO:0060017 8 5 0,000 0,01082241 0,09610633 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01082241 0,09573669 ! anagen GO:0042640 6 5 0,000 0,01082241 0,09536989 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01082241 0,09500588 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01082241 0,09464464 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01082241 0,09428614 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01082241 0,09393034 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01082241 0,09357722 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01082241 0,09322674 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01082241 0,09287888 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01082241 0,09253361 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01082241 0,09219089 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01082241 0,0918507 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01082241 0,09151302 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01082241 0,0911778 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01082241 0,09084504 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01082241 0,09051469 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01082241 0,09018674 ! ovulation GO:0030728 6 5 0,000 0,01082241 0,08986116 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01082241 0,08953792 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01082241 0,08921699 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01082241 0,08889836 ! response to pH GO:0009268 9 5 0,000 0,01082241 0,08858199 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01082241 0,08826787 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01082241 0,08795597 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01082241 0,08764627 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01082241 0,08733874 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01082241 0,08703336 ! polyol catabolic process GO:0046174 7 5 0,000 0,01082241 0,08673011 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01082241 0,08642896 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01082241 0,0861299 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01082241 0,0858329 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01082241 0,08553794 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01082241 0,085245 ! urea metabolic process GO:0019627 6 5 0,000 0,01082241 0,08495406 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01082241 0,0846651 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01082241 0,0843781 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01082241 0,08409304 ! neutrophil activation GO:0042119 5 5 0,000 0,01082241 0,0838099 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01082241 0,08352866 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01082241 0,0832493 ! response to food GO:0032094 5 5 0,000 0,01082241 0,0829718 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01082241 0,08269615 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01082241 0,08242232 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01082241 0,0821503 ! forebrain neuron development GO:0021884 7 5 0,000 0,01082241 0,08188007 ! melanosome organization GO:0032438 7 5 0,000 0,01082241 0,08161161 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01082241 0,0813449 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01082241 0,08107994 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01082241 0,08081669 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01082241 0,08055515 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01082241 0,08029529 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01082241 0,08003711 ! nucleoside transport GO:0015858 6 5 0,000 0,01082241 0,07978058 ! nucleoside salvage GO:0043174 7 5 0,000 0,01082241 0,07952569 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01082241 0,07927242 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01082241 0,07902076 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01082241 0,0787707 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01082241 0,07852221 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01082241 0,07827528 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01082241 0,07802991 ! depyrimidination GO:0045008 8 5 0,000 0,01082241 0,07778606 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01082241 0,07754374 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01082241 0,07730292 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01082241 0,07706359 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01082241 0,07682574 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01082241 0,07658936 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01082241 0,07635442 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01082241 0,07612092 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01082241 0,07588884 ! monocyte differentiation GO:0030224 8 5 0,000 0,01082241 0,07565818 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01082241 0,07542891 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01082241 0,07520103 ! centrosome duplication GO:0051298 5 5 0,000 0,01082241 0,07497452 ! response to UV-C GO:0010225 6 5 0,000 0,01082241 0,07474937 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01082241 0,07452557 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01082241 0,07430311 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01082241 0,07408197 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01082241 0,07386214 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01082241 0,07364361 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01082241 0,07342637 ! melanosome transport GO:0032402 8 5 0,000 0,01082241 0,07321041 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01082241 0,07299572 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01082241 0,07278228 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01082241 0,07257009 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01082241 0,07235913 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01082241 0,07214939 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01082241 0,07194087 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01082241 0,07173355 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01082241 0,07152742 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01082241 0,07132247 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01082241 0,07111869 ! neural tube patterning GO:0021532 6 5 0,000 0,01082241 0,07091607 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01082241 0,0707146 ! histone demethylation GO:0016577 9 5 0,000 0,01082241 0,07051428 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01082241 0,07031509 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01082241 0,07011702 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01082241 0,06992006 ! enteric nervous system development GO:0048484 8 5 0,000 0,01082241 0,0697242 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01082241 0,06952944 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01082241 0,06933577 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01082241 0,06914317 ! transcription termination GO:0006353 8 5 0,000 0,01082241 0,06895164 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01082241 0,06876116 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01082241 0,06857174 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01082241 0,06838335 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01082241 0,068196 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01082241 0,06800967 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01082241 0,06782436 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01082241 0,06764006 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01082241 0,06745675 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01082241 0,06727443 ! apical protein localization GO:0045176 6 5 0,000 0,01082241 0,0670931 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01082241 0,06691274 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01082241 0,06673335 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01082241 0,06655492 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01082241 0,06637744 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01082241 0,06620091 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01082241 0,06602531 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01082241 0,06585064 ! glial cell migration GO:0008347 10 5 0,000 0,01082241 0,06567689 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01082241 0,06550405 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01082241 0,06533213 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01082241 0,0651611 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01082241 0,06499097 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01082241 0,06482172 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01082241 0,06465335 ! neural plate development GO:0001840 6 5 0,000 0,01082241 0,06448586 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01082241 0,06431923 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01082241 0,06415346 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01082241 0,06398854 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01082241 0,06382446 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01082241 0,06366123 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01082241 0,06349883 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01082241 0,06333725 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01082241 0,0631765 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01082241 0,06301656 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01082241 0,06285743 ! spindle assembly GO:0051225 5 5 0,000 0,01082241 0,06269909 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01082241 0,06254156 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01082241 0,06238481 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01082241 0,06222885 ! organ regeneration GO:0031100 7 5 0,000 0,01082241 0,06207367 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01082241 0,06191926 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01082241 0,06176561 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01082241 0,06161272 GO:0055081|anion homeostasis, ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,0109719 0,06230958 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,01126134 0,06379578 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,01126134 0,06363903 ! response to inorganic substance GO:0010035 115 75 1,000 0,01155414 0,06513361 ! regulation of protein transport GO:0051223 114 76 1,000 0,01185027 0,06663969 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 148 77 1,000 0,01214974 0,06815708 ! T cell activation GO:0042110 134 79 1,000 0,0127586 0,07139847 ! tRNA transcription GO:0009304 11 6 0,000 0,01297316 0,072423 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01297316 0,07224765 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01297316 0,07207313 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01297316 0,07189946 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01297316 0,07172663 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01297316 0,07155462 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01297316 0,07138344 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01297316 0,07121307 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01297316 0,07104352 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01297316 0,07087477 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01297316 0,07070682 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01297316 0,07053966 ! prostate gland development GO:0030850 9 6 0,000 0,01297316 0,0703733 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01297316 0,07020771 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01297316 0,0700429 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01297316 0,06987887 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01297316 0,0697156 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01297316 0,06955309 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01297316 0,06939134 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01297316 0,06923034 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01297316 0,06907009 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01297316 0,06891057 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01297316 0,06875179 ! neuron adhesion GO:0007158 9 6 0,000 0,01297316 0,06859374 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01297316 0,06843642 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01297316 0,06827981 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01297316 0,06812392 ! signal peptide processing GO:0006465 8 6 0,000 0,01297316 0,06796874 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01297316 0,06781427 ! mRNA stabilization GO:0048255 15 6 0,000 0,01297316 0,06766049 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01297316 0,06750742 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01297316 0,06735503 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01297316 0,06720333 ! opsonization GO:0008228 8 6 0,000 0,01297316 0,06705231 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01297316 0,06690197 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01297316 0,0667523 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01297316 0,0666033 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01297316 0,06645496 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01297316 0,06630728 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01297316 0,06616026 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01297316 0,06601389 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01297316 0,06586816 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01297316 0,06572308 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01297316 0,06557863 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01297316 0,06543482 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01297316 0,06529164 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01297316 0,06514908 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01297316 0,06500714 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01297316 0,06486582 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01297316 0,06472511 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01297316 0,06458502 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01297316 0,06444552 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01297316 0,06430663 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01297316 0,06416834 ! thymic T cell selection GO:0045061 12 6 0,000 0,01297316 0,06403064 ! protein lipoylation GO:0009249 10 6 0,000 0,01297316 0,06389353 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01297316 0,063757 ! pigment granule organization GO:0048753 11 6 0,000 0,01297316 0,06362106 ! drug transport GO:0015893 6 6 0,000 0,01297316 0,0634857 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01297316 0,06335091 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01297316 0,06321669 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01297316 0,06308304 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01297316 0,06294995 ! histidine metabolic process GO:0006547 6 6 0,000 0,01297316 0,06281743 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01297316 0,06268546 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01297316 0,06255404 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01297316 0,06242317 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01297316 0,06229285 ! adenohypophysis development GO:0021984 10 6 0,000 0,01297316 0,06216308 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01297316 0,06203384 ! hyperosmotic response GO:0006972 8 6 0,000 0,01297316 0,06190514 ! microtubule nucleation GO:0007020 10 6 0,000 0,01297316 0,06177697 ! ER overload response GO:0006983 7 6 0,000 0,01297316 0,06164933 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01297316 0,06152222 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01297316 0,06139563 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01297316 0,06126956 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01297316 0,06114401 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01297316 0,06101897 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01297316 0,06089444 ! response to dietary excess GO:0002021 7 6 0,000 0,01297316 0,06077042 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01297316 0,06064691 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01297316 0,06052389 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01297316 0,06040137 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01297316 0,06027935 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01297316 0,06015782 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01297316 0,06003678 ! neuron apoptosis GO:0051402 8 6 0,000 0,01297316 0,05991622 ! organic alcohol transport GO:0015850 9 6 0,000 0,01297316 0,05979615 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01297316 0,05967655 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01297316 0,05955744 ! male sex determination GO:0030238 9 6 0,000 0,01297316 0,0594388 ! carnitine transport GO:0015879 8 6 0,000 0,01297316 0,05932063 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01297316 0,05920293 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01297316 0,0590857 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01297316 0,05896893 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01297316 0,05885262 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01297316 0,05873677 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01297316 0,05862137 ! parturition GO:0007567 12 6 0,000 0,01297316 0,05850643 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01297316 0,05839193 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01297316 0,05827789 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01297316 0,05816428 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01297316 0,05805112 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01297316 0,0579384 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01297316 0,05782612 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01297316 0,05771427 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01297316 0,05760285 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01297316 0,05749186 ! macrophage differentiation GO:0030225 10 6 0,000 0,01297316 0,0573813 ! astrocyte development GO:0014002 14 6 0,000 0,01297316 0,05727117 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01297316 0,05716145 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01297316 0,05705216 ! interaction with symbiont GO:0051702 8 6 0,000 0,01297316 0,05694328 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01297316 0,05683481 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01297316 0,05672676 ! eating behavior GO:0042755 6 6 0,000 0,01297316 0,05661912 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01297316 0,05651189 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01297316 0,05640506 ! DNA topological change GO:0006265 8 6 0,000 0,01297316 0,05629864 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01297316 0,05619261 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01297316 0,05608699 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01297316 0,05598176 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01297316 0,05587692 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01297316 0,05577248 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01297316 0,05566843 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01297316 0,05556476 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01297316 0,05546148 ! hair follicle maturation GO:0048820 7 6 0,000 0,01297316 0,05535859 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01297316 0,05525607 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01297316 0,05515393 ! Schwann cell development GO:0014044 14 6 0,000 0,01297316 0,05505217 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01297316 0,05495079 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01297316 0,05484977 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01297316 0,05474913 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01297316 0,05464886 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01297316 0,05454895 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01297316 0,05444941 ! histone ubiquitination GO:0016574 7 6 0,000 0,01297316 0,05435023 ! regulation of meiosis GO:0040020 10 6 0,000 0,01297316 0,05425141 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01297316 0,05415295 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01297316 0,05405485 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01297316 0,0539571 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01297316 0,05385971 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01297316 0,05376266 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01297316 0,05366597 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01297316 0,05356962 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01297316 0,05347362 ! receptor internalization GO:0031623 9 6 0,000 0,01297316 0,05337796 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01297316 0,05328264 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01297316 0,05318766 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01297316 0,05309302 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01297316 0,05299872 ! protein deubiquitination GO:0016579 8 6 0,000 0,01297316 0,05290475 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01297316 0,05281111 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01297316 0,0527178 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01297316 0,05262483 ! axonal fasciculation GO:0007413 9 6 0,000 0,01297316 0,05253218 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01297316 0,05243985 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01297316 0,05234786 ! midbrain development GO:0030901 6 6 0,000 0,01297316 0,05225618 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01297316 0,05216482 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01297316 0,05207378 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01297316 0,05198306 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01297316 0,05189266 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01297316 0,05180257 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01297316 0,05171279 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01297316 0,05162332 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01297316 0,05153416 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01297316 0,05144531 ! adult feeding behavior GO:0008343 6 6 0,000 0,01297316 0,05135676 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01297316 0,05126852 ! blastocyst growth GO:0001832 15 6 0,000 0,01297316 0,05118058 ! pigment granule transport GO:0051904 12 6 0,000 0,01297316 0,05109294 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01297316 0,0510056 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01297316 0,05091856 ! catecholamine transport GO:0051937 7 6 0,000 0,01297316 0,05083182 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01297316 0,05074537 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01297316 0,05065921 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01297316 0,05057335 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01297316 0,05048778 ! protein prenylation GO:0018342 10 6 0,000 0,01297316 0,0504025 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01297316 0,0503175 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01297316 0,05023279 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01297316 0,05014837 ! forebrain development GO:0030900 131 80 1,000 0,01306796 0,05043003 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01338058 0,05154998 GO:0002696|positive regulation of leukocyte activation, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,01401558 0,05390608 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,01466347 0,05630382 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,01466347 0,05620998 ! regulation of protein localization GO:0032880 132 85 1,000 0,01466347 0,05611645 ! regulation of membrane potential GO:0042391 128 85 1,000 0,01466347 0,05602324 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,01466347 0,05593033 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01511937 0,05757374 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01511937 0,05747858 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01511937 0,05738373 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01511937 0,05728919 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01511937 0,05719497 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01511937 0,05710105 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01511937 0,05700744 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01511937 0,05691414 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01511937 0,05682115 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01511937 0,05672845 ! reproductive behavior GO:0019098 12 7 0,000 0,01511937 0,05663606 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01511937 0,05654397 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01511937 0,05645218 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01511937 0,05636068 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01511937 0,05626948 ! oligopeptide transport GO:0006857 11 7 0,000 0,01511937 0,05617858 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01511937 0,05608797 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01511937 0,05599765 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,01511937 0,05590762 ! pericardium development GO:0060039 8 7 0,000 0,01511937 0,05581788 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01511937 0,05572843 ! fibril organization GO:0043206 13 7 0,000 0,01511937 0,05563927 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01511937 0,05555039 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01511937 0,05546179 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01511937 0,05537347 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01511937 0,05528544 ! lipoprotein transport GO:0042953 9 7 0,000 0,01511937 0,05519768 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01511937 0,05511021 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01511937 0,05502301 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01511937 0,05493608 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01511937 0,05484943 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01511937 0,05476306 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01511937 0,05467695 ! chemosensory behavior GO:0007635 9 7 0,000 0,01511937 0,05459112 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01511937 0,05450555 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01511937 0,05442025 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01511937 0,05433522 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01511937 0,05425045 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01511937 0,05416595 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01511937 0,05408171 ! reflex GO:0060004 12 7 0,000 0,01511937 0,05399773 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01511937 0,05391402 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01511937 0,05383056 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01511937 0,05374736 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01511937 0,05366442 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01511937 0,05358173 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01511937 0,05349929 ! spinal cord patterning GO:0021511 7 7 0,000 0,01511937 0,05341711 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01511937 0,05333519 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01511937 0,05325351 ! adrenal gland development GO:0030325 17 7 0,000 0,01511937 0,05317208 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01511937 0,0530909 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01511937 0,05300997 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01511937 0,05292929 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01511937 0,05284885 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01511937 0,05276865 ! endosome organization GO:0007032 10 7 0,000 0,01511937 0,0526887 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01511937 0,05260899 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01511937 0,05252952 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01511937 0,05245029 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01511937 0,0523713 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01511937 0,05229254 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01511937 0,05221403 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01511937 0,05213574 ! galactose metabolic process GO:0006012 10 7 0,000 0,01511937 0,0520577 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01511937 0,05197988 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01511937 0,0519023 ! organ growth GO:0035265 11 7 0,000 0,01511937 0,05182495 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01511937 0,05174783 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01511937 0,05167094 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01511937 0,05159427 ! retinol metabolic process GO:0042572 9 7 0,000 0,01511937 0,05151784 ! behavioral fear response GO:0001662 13 7 0,000 0,01511937 0,05144163 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01511937 0,05136564 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01511937 0,05128988 ! rRNA modification GO:0000154 12 7 0,000 0,01511937 0,05121435 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01511937 0,05113903 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01511937 0,05106394 ! response to UV-B GO:0010224 11 7 0,000 0,01511937 0,05098906 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01511937 0,05091441 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01511937 0,05083997 ! intermediate filament organization GO:0045109 11 7 0,000 0,01511937 0,05076575 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01511937 0,05069175 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01511937 0,05061796 ! fibrinolysis GO:0042730 9 7 0,000 0,01511937 0,05054439 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01511937 0,05047103 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01511937 0,05039789 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01511937 0,05032495 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01511937 0,05025223 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01511937 0,05017971 ! response to tropane GO:0014073 13 7 0,000 0,01511937 0,05010741 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01511937 0,05003531 ! melanosome localization GO:0032400 10 7 0,000 0,01511937 0,04996342 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01511937 0,04989174 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01511937 0,04982026 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01511937 0,04974899 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01511937 0,04967792 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01511937 0,04960705 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01511937 0,04953638 ! mast cell activation GO:0045576 9 7 0,000 0,01511937 0,04946592 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01511937 0,04939566 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01511937 0,04932559 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01511937 0,04925572 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01511937 0,04918606 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01511937 0,04911658 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01511937 0,04904731 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01511937 0,04897823 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01511937 0,04890934 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01511937 0,04884065 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01511937 0,04877215 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01511937 0,04870384 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01511937 0,04863572 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01511937 0,0485678 ! response to tumor cell GO:0002347 12 7 0,000 0,01511937 0,04850006 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01511937 0,04843251 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01511937 0,04836515 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01511937 0,04829797 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01511937 0,04823099 ! diuresis GO:0030146 12 7 0,000 0,01511937 0,04816418 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01511937 0,04809757 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01511937 0,04803113 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01511937 0,04796488 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01511937 0,04789882 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01511937 0,04783293 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01511937 0,04776723 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01511937 0,0477017 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01511937 0,04763636 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01511937 0,04757119 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01511937 0,0475062 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01511937 0,04744139 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01511937 0,04737676 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01511937 0,0473123 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01511937 0,04724802 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01511937 0,04718391 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01511937 0,04711997 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01511937 0,04705621 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01511937 0,04699262 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01511937 0,04692921 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01511937 0,04686596 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01511937 0,04680288 ! muscle adaptation GO:0043500 12 7 0,000 0,01511937 0,04673997 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01511937 0,04667724 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01511937 0,04661467 ! retina homeostasis GO:0001895 9 7 0,000 0,01511937 0,04655226 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01511937 0,04649003 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01511937 0,04642796 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01511937 0,04636605 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01511937 0,04630432 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01511937 0,04624274 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01511937 0,04618133 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01511937 0,04612008 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,01532414 0,04668281 GO:0060538|skeletal muscle organ development, ! regulation of neurogenesis GO:0050767 153 89 1,000 0,01599747 0,04866954 ! regulation of T cell activation GO:0050863 128 89 1,000 0,01599747 0,04860525 ! leukocyte differentiation GO:0002521 143 90 1,000 0,01633884 0,04957696 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,01703094 0,0516089 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01726102 0,05223731 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01726102 0,05216866 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01726102 0,0521002 ! axon extension GO:0048675 11 8 0,000 0,01726102 0,05203192 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01726102 0,05196381 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01726102 0,05189589 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01726102 0,05182814 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01726102 0,05176057 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01726102 0,05169317 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01726102 0,05162595 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01726102 0,0515589 ! phosphate transport GO:0006817 10 8 0,000 0,01726102 0,05149203 ! N-glycan processing GO:0006491 12 8 0,000 0,01726102 0,05142533 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01726102 0,0513588 ! UTP metabolic process GO:0046051 8 8 0,000 0,01726102 0,05129245 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01726102 0,05122626 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01726102 0,05116025 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01726102 0,05109441 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01726102 0,05102873 ! succinate metabolic process GO:0006105 14 8 0,000 0,01726102 0,05096323 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01726102 0,05089789 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01726102 0,05083272 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01726102 0,05076772 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01726102 0,05070288 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01726102 0,05063821 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01726102 0,0505737 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01726102 0,05050936 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01726102 0,05044518 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01726102 0,05038116 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01726102 0,0503173 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01726102 0,05025361 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01726102 0,05019008 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01726102 0,05012671 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01726102 0,0500635 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01726102 0,05000045 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01726102 0,04993755 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01726102 0,04987482 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01726102 0,04981224 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01726102 0,04974982 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01726102 0,04968755 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01726102 0,04962544 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01726102 0,04956349 ! melanin metabolic process GO:0006582 12 8 0,000 0,01726102 0,04950169 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01726102 0,04944004 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01726102 0,04937855 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01726102 0,04931721 ! macrophage activation GO:0042116 12 8 0,000 0,01726102 0,04925602 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01726102 0,04919499 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01726102 0,0491341 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01726102 0,04907337 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01726102 0,04901278 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01726102 0,04895235 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01726102 0,04889206 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01726102 0,04883192 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01726102 0,04877193 ! ruffle organization GO:0031529 11 8 0,000 0,01726102 0,04871209 ! osteoblast development GO:0002076 13 8 0,000 0,01726102 0,04865239 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01726102 0,04859284 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01726102 0,04853344 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01726102 0,04847418 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01726102 0,04841507 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01726102 0,04835609 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01726102 0,04829727 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01726102 0,04823858 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01726102 0,04818004 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01726102 0,04812164 ! brain morphogenesis GO:0048854 20 8 0,000 0,01726102 0,04806338 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01726102 0,04800526 ! segment specification GO:0007379 10 8 0,000 0,01726102 0,04794729 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01726102 0,04788945 ! cellular extravasation GO:0045123 11 8 0,000 0,01726102 0,04783175 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01726102 0,04777419 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01726102 0,04771677 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01726102 0,04765949 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01726102 0,04760234 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01726102 0,04754533 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01726102 0,04748846 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01726102 0,04743172 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01726102 0,04737512 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01726102 0,04731866 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01726102 0,04726233 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01726102 0,04720613 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01726102 0,04715006 ! icosanoid secretion GO:0032309 12 8 0,000 0,01726102 0,04709413 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01726102 0,04703833 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01726102 0,04698267 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01726102 0,04692713 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01726102 0,04687173 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01726102 0,04681645 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01726102 0,04676131 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01726102 0,0467063 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01726102 0,04665141 ! sterol catabolic process GO:0016127 9 8 0,000 0,01726102 0,04659666 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01726102 0,04654203 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01726102 0,04648753 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01726102 0,04643316 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01726102 0,04637892 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01726102 0,0463248 ! prophase GO:0051324 11 8 0,000 0,01726102 0,04627081 ! S phase GO:0051320 8 8 0,000 0,01726102 0,04621694 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01726102 0,0461632 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01726102 0,04610959 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01726102 0,04605609 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01726102 0,04600273 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01726102 0,04594948 ! hormone catabolic process GO:0042447 13 8 0,000 0,01726102 0,04589636 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01726102 0,04584336 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01726102 0,04579049 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01726102 0,04573773 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01726102 0,0456851 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01726102 0,04563259 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01726102 0,0455802 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01726102 0,04552793 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01726102 0,04547578 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01726102 0,04542375 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01726102 0,04537183 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01726102 0,04532004 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01726102 0,04526836 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01726102 0,0452168 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01726102 0,04516536 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01726102 0,04511404 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01726102 0,04506283 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,01738163 0,04532625 ! angiogenesis GO:0001525 149 95 1,000 0,01809224 0,04712588 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,01845212 0,04800892 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01845212 0,04795467 ! response to light stimulus GO:0009416 153 96 1,000 0,01845212 0,04790055 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01939815 0,05029959 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01939815 0,05024295 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01939815 0,05018643 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01939815 0,05013004 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01939815 0,05007378 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01939815 0,05001764 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01939815 0,04996163 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01939815 0,04990574 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01939815 0,04984998 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01939815 0,04979435 ! GTP metabolic process GO:0046039 9 9 0,000 0,01939815 0,04973884 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01939815 0,04968345 ! social behavior GO:0035176 14 9 0,000 0,01939815 0,04962818 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01939815 0,04957304 ! artery development GO:0060840 19 9 0,000 0,01939815 0,04951802 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01939815 0,04946312 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01939815 0,04940834 ! response to pain GO:0048265 16 9 0,000 0,01939815 0,04935369 ! protein complex disassembly GO:0043241 17 9 0,000 0,01939815 0,04929916 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01939815 0,04924474 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01939815 0,04919045 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01939815 0,04913627 ! lung alveolus development GO:0048286 17 9 0,000 0,01939815 0,04908222 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01939815 0,04902828 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01939815 0,04897446 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01939815 0,04892076 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01939815 0,04886718 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01939815 0,04881371 ! protein targeting to ER GO:0045047 19 9 0,000 0,01939815 0,04876037 ! T cell selection GO:0045058 18 9 0,000 0,01939815 0,04870713 ! endoderm development GO:0007492 12 9 0,000 0,01939815 0,04865402 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01939815 0,04860102 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01939815 0,04854813 ! arginine catabolic process GO:0006527 10 9 0,000 0,01939815 0,04849536 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01939815 0,04844271 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01939815 0,04839017 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01939815 0,04833774 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01939815 0,04828543 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01939815 0,04823323 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01939815 0,04818114 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01939815 0,04812916 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01939815 0,0480773 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01939815 0,04802555 ! mannose metabolic process GO:0006013 9 9 0,000 0,01939815 0,04797391 ! receptor clustering GO:0043113 15 9 0,000 0,01939815 0,04792238 ! epithelial cell development GO:0002064 10 9 0,000 0,01939815 0,04787096 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01939815 0,04781965 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01939815 0,04776845 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01939815 0,04771736 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01939815 0,04766638 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01939815 0,04761551 ! motor axon guidance GO:0008045 14 9 0,000 0,01939815 0,04756475 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01939815 0,0475141 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01939815 0,04746355 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01939815 0,04741311 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01939815 0,04736278 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01939815 0,04731255 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01939815 0,04726243 ! DNA ligation GO:0006266 14 9 0,000 0,01939815 0,04721242 ! response to amine stimulus GO:0014075 13 9 0,000 0,01939815 0,04716251 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01939815 0,04711271 ! erythrocyte development GO:0048821 11 9 0,000 0,01939815 0,04706301 ! renal water homeostasis GO:0003091 14 9 0,000 0,01939815 0,04701342 ! postreplication repair GO:0006301 11 9 0,000 0,01939815 0,04696393 ! mRNA cleavage GO:0006379 13 9 0,000 0,01939815 0,04691455 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01939815 0,04686527 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01939815 0,04681609 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01939815 0,04676702 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01939815 0,04671805 ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01939815 0,04666918 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01939815 0,04662041 ! acid secretion GO:0046717 14 9 0,000 0,01939815 0,04657175 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01939815 0,04652319 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01939815 0,04647472 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01939815 0,04642636 ! purine base metabolic process GO:0006144 18 9 0,000 0,01939815 0,0463781 ! oocyte differentiation GO:0009994 12 9 0,000 0,01939815 0,04632994 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01939815 0,04628188 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01939815 0,04623392 ! spleen development GO:0048536 15 9 0,000 0,01939815 0,04618606 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01939815 0,0461383 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01939815 0,04609064 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01939815 0,04604307 ! detection of calcium ion GO:0005513 13 9 0,000 0,01939815 0,0459956 ! blastocyst formation GO:0001825 12 9 0,000 0,01939815 0,04594823 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01939815 0,04590096 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01939815 0,04585379 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01939815 0,04580671 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01939815 0,04575973 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01939815 0,04571284 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01939815 0,04566605 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01939815 0,04561936 ! prepulse inhibition GO:0060134 14 9 0,000 0,01939815 0,04557276 ! embryonic placenta development GO:0001892 12 9 0,000 0,01939815 0,04552626 ! insulin secretion GO:0030073 17 9 0,000 0,01939815 0,04547985 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01939815 0,04543354 ! response to nicotine GO:0035094 16 9 0,000 0,01939815 0,04538732 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01939815 0,04534119 ! nucleus localization GO:0051647 15 9 0,000 0,01939815 0,04529516 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01939815 0,04524922 ! calcium ion transport GO:0006816 167 99 1,000 0,01954993 0,04555709 ! extracellular structure organization GO:0043062 156 99 1,000 0,01954993 0,04551098 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,01992187 0,04632994 ! divalent metal ion transport GO:0070838 171 100 1,000 0,01992187 0,04628314 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02153074 0,04997044 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02153074 0,04992007 ! neuron fate specification GO:0048665 11 10 0,000 0,02153074 0,0498698 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02153074 0,04981963 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02153074 0,04976956 ! thyroid gland development GO:0030878 19 10 0,000 0,02153074 0,04971959 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,02153074 0,04966972 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02153074 0,04961995 ! synapsis GO:0007129 13 10 0,000 0,02153074 0,04957028 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02153074 0,04952071 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02153074 0,04947124 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02153074 0,04942187 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02153074 0,04937259 ! sulfate transport GO:0008272 12 10 0,000 0,02153074 0,04932342 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02153074 0,04927434 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02153074 0,04922536 ! androgen metabolic process GO:0008209 13 10 0,000 0,02153074 0,04917647 ! phospholipid efflux GO:0033700 16 10 0,000 0,02153074 0,04912769 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02153074 0,049079 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02153074 0,0490304 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02153074 0,04898191 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02153074 0,04893351 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02153074 0,0488852 ! pathogenesis GO:0009405 13 10 0,000 0,02153074 0,04883699 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02153074 0,04878888 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02153074 0,04874086 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02153074 0,04869293 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02153074 0,0486451 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02153074 0,04859736 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02153074 0,04854971 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02153074 0,04850216 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02153074 0,04845471 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02153074 0,04840734 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02153074 0,04836007 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02153074 0,04831289 ! response to X-ray GO:0010165 16 10 0,000 0,02153074 0,0482658 ! B cell proliferation GO:0042100 14 10 0,000 0,02153074 0,0482188 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02153074 0,0481719 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02153074 0,04812508 ! forebrain cell migration GO:0021885 17 10 0,000 0,02153074 0,04807836 ! lipid digestion GO:0044241 15 10 0,000 0,02153074 0,04803173 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02153074 0,04798518 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02153074 0,04793873 ! UV protection GO:0009650 14 10 0,000 0,02153074 0,04789237 ! entry into host cell GO:0030260 20 10 0,000 0,02153074 0,0478461 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02153074 0,04779991 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02153074 0,04775382 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02153074 0,04770781 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02153074 0,0476619 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02153074 0,04761607 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02153074 0,04757033 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02153074 0,04752467 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02153074 0,04747911 ! regulation of organ growth GO:0046620 11 10 0,000 0,02153074 0,04743363 ! response to dsRNA GO:0043331 18 10 0,000 0,02153074 0,04738824 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02153074 0,04734293 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02153074 0,04729772 ! embryonic axis specification GO:0000578 12 10 0,000 0,02153074 0,04725258 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02153074 0,04720754 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02153074 0,04716258 ! cranial nerve development GO:0021545 12 10 0,000 0,02153074 0,04711771 ! fucose catabolic process GO:0019317 16 10 0,000 0,02153074 0,04707292 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02153074 0,04702821 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02153074 0,04698359 ! protein sumoylation GO:0016925 12 10 0,000 0,02153074 0,04693906 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02153074 0,04689461 ! zymogen activation GO:0031638 14 10 0,000 0,02153074 0,04685025 ! salivary gland development GO:0007431 22 10 0,000 0,02153074 0,04680596 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02153074 0,04676176 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02153074 0,04671765 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02153074 0,04667362 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02153074 0,04662967 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02153074 0,0465858 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02153074 0,04654202 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02153074 0,04649832 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02153074 0,0464547 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02153074 0,04641116 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02153074 0,04636771 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02153074 0,04632433 ! detection of bacterium GO:0016045 10 10 0,000 0,02153074 0,04628104 ! embryonic gut development GO:0048566 11 10 0,000 0,02153074 0,04623782 ! activation of innate immune response GO:0002218 10 10 0,000 0,02153074 0,04619469 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02153074 0,04615164 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02153074 0,04610867 ! developmental induction GO:0031128 13 10 0,000 0,02153074 0,04606578 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02153074 0,04602296 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02153074 0,04598023 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02153074 0,04593758 ! rRNA transcription GO:0009303 17 11 0,000 0,02365882 0,05043123 ! respiratory burst GO:0045730 14 11 0,000 0,02365882 0,05038453 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02365882 0,05033792 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02365882 0,0502914 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02365882 0,05024496 ! virus-host interaction GO:0019048 17 11 0,000 0,02365882 0,05019861 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02365882 0,05015235 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02365882 0,05010617 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02365882 0,05006007 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02365882 0,05001406 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02365882 0,04996813 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02365882 0,04992229 ! mating GO:0007618 14 11 0,000 0,02365882 0,04987653 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02365882 0,04983086 ! T cell proliferation GO:0042098 20 11 0,000 0,02365882 0,04978527 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02365882 0,04973976 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02365882 0,04969433 ! bone resorption GO:0045453 16 11 0,000 0,02365882 0,04964899 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02365882 0,04960373 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02365882 0,04955856 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02365882 0,04951346 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02365882 0,04946845 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02365882 0,04942352 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02365882 0,04937867 ! syncytium formation GO:0006949 15 11 0,000 0,02365882 0,0493339 ! plasma membrane organization GO:0007009 18 11 0,000 0,02365882 0,04928922 ! focal adhesion formation GO:0048041 24 11 0,000 0,02365882 0,04924461 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02365882 0,04920009 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02365882 0,04915564 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02365882 0,04911128 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02365882 0,04906699 ! adult heart development GO:0007512 11 11 0,000 0,02365882 0,04902279 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02365882 0,04897866 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02365882 0,04893462 ! temperature homeostasis GO:0001659 16 11 0,000 0,02365882 0,04889065 ! L-glutamate transport GO:0015813 16 11 0,000 0,02365882 0,04884676 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02365882 0,04880296 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02365882 0,04875923 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02365882 0,04871557 ! stem cell development GO:0048864 29 11 0,000 0,02365882 0,048672 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02365882 0,0486285 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02365882 0,04858509 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02365882 0,04854174 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02365882 0,04849848 ! vasoconstriction GO:0042310 15 11 0,000 0,02365882 0,04845529 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02365882 0,04841218 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02365882 0,04836915 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02365882 0,04832619 ! ribosome assembly GO:0042255 13 11 0,000 0,02365882 0,04828331 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02365882 0,04824051 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02365882 0,04819778 ! chromatin silencing GO:0006342 19 11 0,000 0,02365882 0,04815513 ! nucleosome positioning GO:0016584 13 11 0,000 0,02365882 0,04811255 ! T cell homeostasis GO:0043029 20 11 0,000 0,02365882 0,04807005 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02365882 0,04802762 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02365882 0,04798527 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02365882 0,04794299 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02365882 0,04790079 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02365882 0,04785866 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02365882 0,0478166 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02365882 0,04777462 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02365882 0,04773272 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02365882 0,04769088 ! male genitalia development GO:0030539 13 11 0,000 0,02365882 0,04764912 ! cholesterol efflux GO:0033344 19 11 0,000 0,02365882 0,04760743 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02365882 0,04756582 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02365882 0,04752428 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02365882 0,04748281 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02365882 0,04744141 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02365882 0,04740008 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02365882 0,04735883 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02365882 0,04731765 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02365882 0,04727654 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02365882 0,0472355 ! lysogeny GO:0030069 18 11 0,000 0,02365882 0,04719453 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02365882 0,04715364 ! acrosome reaction GO:0007340 13 11 0,000 0,02365882 0,04711281 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02365882 0,04707205 ! lactation GO:0007595 20 12 0,000 0,0257824 0,05125282 ! reproductive cellular process GO:0048610 14 12 0,000 0,0257824 0,05120856 ! tRNA modification GO:0006400 14 12 0,000 0,0257824 0,05116438 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,0257824 0,05112027 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,0257824 0,05107624 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,0257824 0,05103229 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,0257824 0,05098841 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,0257824 0,0509446 ! non-recombinational repair GO:0000726 19 12 0,000 0,0257824 0,05090087 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,0257824 0,05085722 ! peroxisomal transport GO:0043574 21 12 0,000 0,0257824 0,05081364 ! cartilage condensation GO:0001502 18 12 0,000 0,0257824 0,05077013 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,0257824 0,0507267 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,0257824 0,05068335 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0257824 0,05064006 ! heart looping GO:0001947 15 12 0,000 0,0257824 0,05059686 ! palate development GO:0060021 15 12 0,000 0,0257824 0,05055372 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,0257824 0,05051066 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,0257824 0,05046767 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,0257824 0,05042476 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0257824 0,05038192 ! arginine metabolic process GO:0006525 13 12 0,000 0,0257824 0,05033915 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,0257824 0,05029645 ! methionine metabolic process GO:0006555 13 12 0,000 0,0257824 0,05025383 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,0257824 0,05021128 ! Golgi organization GO:0007030 18 12 0,000 0,0257824 0,0501688 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,0257824 0,05012639 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,0257824 0,05008405 ! monoamine transport GO:0015844 13 12 0,000 0,0257824 0,05004179 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0257824 0,04999959 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,0257824 0,04995747 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,0257824 0,04991542 ! L-amino acid transport GO:0015807 20 12 0,000 0,0257824 0,04987344 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,0257824 0,04983153 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0257824 0,04978969 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,0257824 0,04974792 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0257824 0,04970622 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,0257824 0,04966459 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,0257824 0,04962303 ! cerebellum development GO:0021549 13 12 0,000 0,0257824 0,04958154 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0257824 0,04954011 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,0257824 0,04949876 ! histone acetylation GO:0016573 23 12 0,000 0,0257824 0,04945748 ! histone methylation GO:0016571 15 12 0,000 0,0257824 0,04941626 ! autonomic nervous system development GO:0048483 23 12 0,000 0,0257824 0,04937512 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,0257824 0,04933404 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,0257824 0,04929303 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,0257824 0,04925209 ! response to gamma radiation GO:0010332 20 12 0,000 0,0257824 0,04921122 ! regulation of epidermis development GO:0045682 17 12 0,000 0,0257824 0,04917041 ! intestinal absorption GO:0050892 19 12 0,000 0,0257824 0,04912967 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,0257824 0,049089 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0257824 0,0490484 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,0257824 0,04900786 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,0257824 0,0489674 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,0257824 0,04892699 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,0257824 0,04888666 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,0257824 0,04884639 ! microspike assembly GO:0030035 23 12 0,000 0,0257824 0,04880619 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,0257824 0,04876605 ! response to cold GO:0009409 14 12 0,000 0,0257824 0,04872598 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02790147 0,05268751 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02790147 0,05264429 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02790147 0,05260114 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02790147 0,05255806 ! water transport GO:0006833 17 13 0,000 0,02790147 0,05251505 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02790147 0,05247211 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02790147 0,05242924 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02790147 0,05238644 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02790147 0,05234371 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02790147 0,05230105 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02790147 0,05225846 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02790147 0,05221594 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02790147 0,05217349 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02790147 0,05213111 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02790147 0,05208879 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02790147 0,05204655 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02790147 0,05200437 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02790147 0,05196226 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02790147 0,05192022 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02790147 0,05187825 ! NAD metabolic process GO:0019674 21 13 0,000 0,02790147 0,05183634 ! exocrine system development GO:0035272 27 13 0,000 0,02790147 0,05179451 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02790147 0,05175274 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02790147 0,05171103 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02790147 0,0516694 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02790147 0,05162783 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02790147 0,05158633 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02790147 0,05154489 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02790147 0,05150353 ! genitalia development GO:0048806 15 13 0,000 0,02790147 0,05146222 ! cellular pigmentation GO:0033059 24 13 0,000 0,02790147 0,05142099 ! tissue regeneration GO:0042246 21 13 0,000 0,02790147 0,05137982 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02790147 0,05133871 ! cofactor transport GO:0051181 19 13 0,000 0,02790147 0,05129768 ! NADP metabolic process GO:0006739 18 13 0,000 0,02790147 0,0512567 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02790147 0,0512158 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02790147 0,05117495 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02790147 0,05113418 ! gas transport GO:0015669 18 13 0,000 0,02790147 0,05109347 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02790147 0,05105282 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02790147 0,05101224 ! regulation of axon extension GO:0030516 23 13 0,000 0,02790147 0,05097172 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02790147 0,05093126 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02790147 0,05089087 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02790147 0,05085055 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02790147 0,05081029 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02790147 0,05077009 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02790147 0,05072995 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,03001606 0,05453155 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,03001606 0,05448851 ! superoxide anion generation GO:0042554 18 14 0,000 0,03001606 0,05444554 ! neuron maturation GO:0042551 21 14 0,000 0,03001606 0,05440264 ! regulation of S phase GO:0033261 18 14 0,000 0,03001606 0,0543598 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,03001606 0,05431703 ! myotube differentiation GO:0014902 21 14 0,000 0,03001606 0,05427433 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,03001606 0,05423169 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,03001606 0,05418913 ! inositol metabolic process GO:0006020 20 14 0,000 0,03001606 0,05414662 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,03001606 0,05410419 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,03001606 0,05406182 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,03001606 0,05401952 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,03001606 0,05397728 ! gene silencing by RNA GO:0031047 20 14 0,000 0,03001606 0,05393511 ! response to cAMP GO:0051591 19 14 0,000 0,03001606 0,05389301 ! startle response GO:0001964 21 14 0,000 0,03001606 0,05385097 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,03001606 0,053809 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,03001606 0,05376709 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,03001606 0,05372525 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,03001606 0,05368347 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,03001606 0,05364176 ! glycine metabolic process GO:0006544 22 14 0,000 0,03001606 0,05360011 ! pituitary gland development GO:0021983 23 14 0,000 0,03001606 0,05355853 ! cellular response to starvation GO:0009267 21 14 0,000 0,03001606 0,05351701 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,03001606 0,05347556 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,03001606 0,05343417 ! regulation of heart rate GO:0002027 23 14 0,000 0,03001606 0,05339284 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,03001606 0,05335158 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,03001606 0,05331038 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,03001606 0,05326925 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,03001606 0,05322818 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,03001606 0,05318717 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,03001606 0,05314622 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,03001606 0,05310534 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,03001606 0,05306452 ! axon cargo transport GO:0008088 27 14 0,000 0,03001606 0,05302377 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,03001606 0,05298307 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,03001606 0,05294244 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,03001606 0,05290187 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,03001606 0,05286137 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03001606 0,05282092 ! mRNA splice site selection GO:0006376 26 14 0,000 0,03001606 0,05278054 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,03001606 0,05274022 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,03001606 0,05269996 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,03001606 0,05265976 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,03001606 0,05261962 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,03001606 0,05257955 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,03001606 0,05253953 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,03001606 0,05249958 ! muscle maintenance GO:0046716 19 14 0,000 0,03001606 0,05245969 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,03001606 0,05241985 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,03001606 0,05238008 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,03001606 0,05234037 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,03001606 0,05230072 ! cell killing GO:0001906 20 14 0,000 0,03001606 0,05226112 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,03001606 0,05222159 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,03001606 0,05218212 ! cilium assembly GO:0042384 20 14 0,000 0,03001606 0,05214271 ! peptide hormone secretion GO:0030072 23 14 0,000 0,03001606 0,05210336 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,03212617 0,05572413 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03212617 0,05568214 ! metencephalon development GO:0022037 19 15 0,000 0,03212617 0,05564021 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03212617 0,05559834 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,03212617 0,05555654 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03212617 0,0555148 ! skin development GO:0043588 25 15 0,000 0,03212617 0,05547312 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03212617 0,05543151 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03212617 0,05538995 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03212617 0,05534846 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03212617 0,05530703 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03212617 0,05526567 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,03212617 0,05522436 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03212617 0,05518312 ! adult walking behavior GO:0007628 25 15 0,000 0,03212617 0,05514194 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03212617 0,05510082 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03212617 0,05505976 ! myoblast differentiation GO:0045445 27 15 0,000 0,03212617 0,05501876 ! centrosome cycle GO:0007098 16 15 0,000 0,03212617 0,05497783 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,03212617 0,05493695 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,03212617 0,05489613 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03212617 0,05485538 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03212617 0,05481469 ! cerebral cortex development GO:0021987 29 15 0,000 0,03212617 0,05477405 ! response to osmotic stress GO:0006970 22 15 0,000 0,03212617 0,05473348 ! vesicle coating GO:0006901 25 15 0,000 0,03212617 0,05469297 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03212617 0,05465251 ! DNA integration GO:0015074 22 15 0,000 0,03212617 0,05461212 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,03212617 0,05457179 ! peptide secretion GO:0002790 27 15 0,000 0,03212617 0,05453151 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,03212617 0,0544913 ! neuron recognition GO:0008038 22 15 0,000 0,03212617 0,05445114 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03212617 0,05441104 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03212617 0,05437101 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,03212617 0,05433103 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03212617 0,05429111 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03212617 0,05425125 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03212617 0,05421144 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03212617 0,0541717 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03212617 0,05413201 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03212617 0,05409238 ! organic cation transport GO:0015695 19 15 0,000 0,03212617 0,05405281 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03212617 0,0540133 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,03212617 0,05397385 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03212617 0,05393445 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03212617 0,05389511 ! defense response to virus GO:0051607 27 15 0,000 0,03212617 0,05385583 ! peptide hormone processing GO:0016486 19 15 0,000 0,03212617 0,0538166 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,03212617 0,05377744 ! protein secretion GO:0009306 27 16 0,000 0,03423181 0,05726049 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03423181 0,05721887 ! hormone secretion GO:0046879 25 16 0,000 0,03423181 0,05717732 ! bone remodeling GO:0046849 24 16 0,000 0,03423181 0,05713583 ! endothelial cell migration GO:0043542 22 16 0,000 0,03423181 0,05709439 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03423181 0,05705302 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,03423181 0,05701171 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03423181 0,05697045 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03423181 0,05692926 ! glial cell development GO:0021782 24 16 0,000 0,03423181 0,05688813 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03423181 0,05684705 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03423181 0,05680604 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03423181 0,05676508 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03423181 0,05672418 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03423181 0,05668335 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,03423181 0,05664257 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03423181 0,05660185 ! fructose metabolic process GO:0006000 20 16 0,000 0,03423181 0,05656118 ! regulation of protein binding GO:0043393 27 16 0,000 0,03423181 0,05652058 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,03423181 0,05648003 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03423181 0,05643955 ! protein export from nucleus GO:0006611 24 16 0,000 0,03423181 0,05639912 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03423181 0,05635875 ! DNA replication initiation GO:0006270 25 16 0,000 0,03423181 0,05631843 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03423181 0,05627818 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03423181 0,05623798 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03423181 0,05619784 ! diencephalon development GO:0021536 25 16 0,000 0,03423181 0,05615775 ! oogenesis GO:0048477 23 16 0,000 0,03423181 0,05611772 ! neural crest cell migration GO:0001755 24 16 0,000 0,03423181 0,05607775 ! G1 phase GO:0051318 27 16 0,000 0,03423181 0,05603784 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03423181 0,05599799 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03423181 0,05595819 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03423181 0,05591844 ! steroid catabolic process GO:0006706 22 16 0,000 0,03423181 0,05587876 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03423181 0,05583913 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,03423181 0,05579955 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03423181 0,05576003 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03423181 0,05572057 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03423181 0,05568117 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03423181 0,05564181 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03423181 0,05560252 ! nerve development GO:0021675 18 16 0,000 0,03423181 0,05556328 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,03423181 0,0555241 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,03423181 0,05548497 ! negative regulation of translation GO:0017148 22 16 0,000 0,03423181 0,05544589 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03633299 0,0588078 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03633299 0,05876644 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03633299 0,05872514 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,03633299 0,0586839 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03633299 0,05864272 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03633299 0,0586016 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03633299 0,05856053 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03633299 0,05851952 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03633299 0,05847857 ! signal complex assembly GO:0007172 29 17 0,000 0,03633299 0,05843768 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03633299 0,05839684 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03633299 0,05835606 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03633299 0,05831534 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03633299 0,05827467 ! memory GO:0007613 25 17 0,000 0,03633299 0,05823406 ! keratinization GO:0031424 17 17 0,000 0,03633299 0,05819351 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03633299 0,05815301 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,03633299 0,05811257 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03633299 0,05807219 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03633299 0,05803186 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03633299 0,05799159 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03633299 0,05795137 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03633299 0,05791121 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03633299 0,05787111 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03633299 0,05783106 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03633299 0,05779106 ! membrane budding GO:0006900 29 17 0,000 0,03633299 0,05775113 ! heme metabolic process GO:0042168 27 17 0,000 0,03633299 0,05771124 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03633299 0,05767141 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03633299 0,05763164 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03633299 0,05759192 ! body fluid secretion GO:0007589 27 17 0,000 0,03633299 0,05755226 ! stem cell differentiation GO:0048863 36 17 0,000 0,03633299 0,05751265 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03633299 0,05747309 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03633299 0,05743359 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03633299 0,05739415 ! sensory perception of pain GO:0019233 23 17 0,000 0,03633299 0,05735476 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03633299 0,05731542 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03633299 0,05727613 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03633299 0,0572369 ! synaptogenesis GO:0007416 24 17 0,000 0,03633299 0,05719773 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03633299 0,0571586 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03633299 0,05711953 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03633299 0,05708052 ! cell-cell junction organization GO:0045216 25 17 0,000 0,03633299 0,05704156 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03633299 0,05700265 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03633299 0,05696379 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03633299 0,05692499 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03633299 0,05688624 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03633299 0,05684754 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03633299 0,05680889 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03842972 0,06004644 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03842972 0,06000567 ! positive regulation of translation GO:0045727 28 18 0,000 0,03842972 0,05996496 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03842972 0,05992431 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03842972 0,05988371 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03842972 0,05984316 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03842972 0,05980267 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03842972 0,05976224 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03842972 0,05972186 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03842972 0,05968153 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03842972 0,05964126 ! axis specification GO:0009798 26 18 0,000 0,03842972 0,05960105 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03842972 0,05956088 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03842972 0,05952078 ! pancreas development GO:0031016 26 18 0,000 0,03842972 0,05948072 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,03842972 0,05944072 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03842972 0,05940077 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03842972 0,05936088 ! response to retinoic acid GO:0032526 25 18 0,000 0,03842972 0,05932104 ! pigmentation during development GO:0048066 31 18 0,000 0,03842972 0,05928126 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03842972 0,05924152 ! fucose metabolic process GO:0006004 26 18 0,000 0,03842972 0,05920184 ! response to fungus GO:0009620 19 18 0,000 0,03842972 0,05916222 ! peptide cross-linking GO:0018149 31 18 0,000 0,03842972 0,05912264 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03842972 0,05908312 ! heart process GO:0003015 27 18 0,000 0,03842972 0,05904366 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03842972 0,05900424 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03842972 0,05896488 ! visual learning GO:0008542 35 18 0,000 0,03842972 0,05892557 ! somitogenesis GO:0001756 24 18 0,000 0,03842972 0,05888631 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03842972 0,05884711 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03842972 0,05880795 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03842972 0,05876885 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03842972 0,0587298 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03842972 0,05869081 ! vitamin transport GO:0051180 24 18 0,000 0,03842972 0,05865186 ! hormone transport GO:0009914 27 18 0,000 0,03842972 0,05861297 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03842972 0,05857412 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03842972 0,05853533 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03842972 0,05849659 ! cell-cell recognition GO:0009988 20 18 0,000 0,03842972 0,05845791 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03842972 0,05841927 ! regulation of glucose import GO:0046324 21 18 0,000 0,03842972 0,05838068 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03842972 0,05834215 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03842972 0,05830366 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03842972 0,05826523 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,040522 0,06139698 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,040522 0,06135656 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,040522 0,06131619 ! positive regulation of ossification GO:0045778 30 19 0,000 0,040522 0,06127588 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,040522 0,06123562 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,040522 0,06119541 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,040522 0,06115526 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,040522 0,06111515 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,040522 0,0610751 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,040522 0,06103511 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,040522 0,06099516 ! regeneration GO:0031099 32 19 0,000 0,040522 0,06095527 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,040522 0,06091543 ! response to alkaloid GO:0043279 32 19 0,000 0,040522 0,06087564 ! sensory perception of taste GO:0050909 23 19 0,000 0,040522 0,06083591 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,040522 0,06079622 ! smooth muscle contraction GO:0006939 36 19 0,000 0,040522 0,06075659 ! peroxisome organization GO:0007031 29 19 0,000 0,040522 0,06071701 ! digestive system process GO:0022600 30 19 0,000 0,040522 0,06067748 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,040522 0,060638 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,040522 0,06059858 ! response to vitamin A GO:0033189 26 19 0,000 0,040522 0,0605592 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,040522 0,06051988 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,040522 0,0604806 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,040522 0,06044138 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,040522 0,06040221 ! response to starvation GO:0042594 30 19 0,000 0,040522 0,06036309 ! sex determination GO:0007530 29 19 0,000 0,040522 0,06032402 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,040522 0,060285 ! plasma membrane fusion GO:0045026 23 19 0,000 0,040522 0,06024603 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,040522 0,06020711 ! cytolysis GO:0019835 20 19 0,000 0,040522 0,06016824 ! renal system process GO:0003014 35 19 0,000 0,040522 0,06012943 ! vasodilation GO:0042311 33 19 0,000 0,040522 0,06009066 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,040522 0,06005194 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,040522 0,06001327 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,040522 0,05997465 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,040522 0,05993608 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,040522 0,05989756 ! sarcomere organization GO:0045214 23 19 0,000 0,040522 0,05985909 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,040522 0,05982067 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,040522 0,0597823 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,040522 0,05974398 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,040522 0,05970571 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,040522 0,05966748 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,040522 0,05962931 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,040522 0,05959118 ! protein stabilization GO:0050821 26 19 0,000 0,040522 0,0595531 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,04260986 0,06258153 ! iron ion transport GO:0006826 37 20 0,000 0,04260986 0,06254159 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,04260986 0,0625017 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,04260986 0,06246187 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,04260986 0,06242208 ! response to vitamin GO:0033273 29 20 0,000 0,04260986 0,06238235 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,04260986 0,06234266 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,04260986 0,06230303 ! spinal cord development GO:0021510 31 20 0,000 0,04260986 0,06226345 ! response to ethanol GO:0045471 37 20 0,000 0,04260986 0,06222392 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,04260986 0,06218443 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,04260986 0,062145 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,04260986 0,06210562 ! chromosome condensation GO:0030261 31 20 0,000 0,04260986 0,06206629 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,04260986 0,06202701 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,04260986 0,06198777 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,04260986 0,06194859 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,04260986 0,06190946 ! DNA modification GO:0006304 28 20 0,000 0,04260986 0,06187037 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,04260986 0,06183134 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,04260986 0,06179235 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,04260986 0,06175341 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,04260986 0,06171453 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,04260986 0,06167569 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,04260986 0,0616369 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,04260986 0,06159816 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,04260986 0,06155947 ! alditol metabolic process GO:0019400 24 20 0,000 0,04260986 0,06152082 ! actin filament-based movement GO:0030048 34 20 0,000 0,04260986 0,06148223 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04469328 0,064448 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04469328 0,06440762 GO:0016444|somatic cell DNA recombination, ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04469328 0,06436729 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,04469328 0,06432701 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04469328 0,06428678 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04469328 0,0642466 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04469328 0,06420647 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04469328 0,06416639 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04469328 0,06412636 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04469328 0,06408638 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04469328 0,06404645 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04469328 0,06400657 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04469328 0,06396674 ! phototransduction GO:0007602 25 21 0,000 0,04469328 0,06392696 ! dendrite development GO:0016358 35 21 0,000 0,04469328 0,06388723 ! visual behavior GO:0007632 39 21 0,000 0,04469328 0,06384755 ! ovarian follicle development GO:0001541 30 21 0,000 0,04469328 0,06380792 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04469328 0,06376833 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04469328 0,0637288 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04469328 0,06368931 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04469328 0,06364988 ! cell aging GO:0007569 32 21 0,000 0,04469328 0,06361049 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04469328 0,06357115 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,04469328 0,06353186 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,04469328 0,06349262 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04469328 0,06345343 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04469328 0,06341428 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04469328 0,06337519 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04469328 0,06333614 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04469328 0,06329714 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04469328 0,06325819 ! fatty acid transport GO:0015908 30 21 0,000 0,04469328 0,06321928 ! immunoglobulin production GO:0002377 33 21 0,000 0,04469328 0,06318043 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04469328 0,06314162 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,04469328 0,06310286 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04469328 0,06306414 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04469328 0,06302548 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,04469328 0,06298686 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04469328 0,06294829 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04469328 0,06290976 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04469328 0,06287129 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04469328 0,06283286 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04469328 0,06279447 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04469328 0,06275614 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04469328 0,06271785 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04469328 0,06267961 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04469328 0,06264141 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04469328 0,06260326 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,0467723 0,06547552 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,0467723 0,0654357 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,0467723 0,06539592 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,0467723 0,06535619 ! viral genome replication GO:0019079 29 22 0,000 0,0467723 0,06531651 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,0467723 0,06527687 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,0467723 0,06523729 ! leukocyte adhesion GO:0007159 38 22 0,000 0,0467723 0,06519775 ! molting cycle process GO:0022404 40 22 0,000 0,0467723 0,06515826 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,0467723 0,06511882 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,0467723 0,06507942 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,0467723 0,06504008 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,0467723 0,06500078 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,0467723 0,06496152 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,0467723 0,06492232 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,0467723 0,06488316 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,0467723 0,06484405 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,0467723 0,06480499 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,0467723 0,06476598 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,0467723 0,06472701 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,0467723 0,06468808 ! regulation of behavior GO:0050795 38 22 0,000 0,0467723 0,06464921 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,0467723 0,06461038 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,0467723 0,0645716 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,0467723 0,06453286 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,0467723 0,06449418 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,0467723 0,06445553 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,0467723 0,06441694 ! blastocyst development GO:0001824 37 22 0,000 0,0467723 0,06437839 ! neural tube closure GO:0001843 33 22 0,000 0,0467723 0,06433988 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,0467723 0,06430143 ! protein tetramerization GO:0051262 39 22 0,000 0,0467723 0,06426301 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04884691 0,06707336 ! neuron fate commitment GO:0048663 32 23 0,000 0,04884691 0,06703334 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04884691 0,06699337 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,04884691 0,06695345 ! myelination GO:0042552 35 23 0,000 0,04884691 0,06691357 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04884691 0,06687374 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04884691 0,06683396 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,04884691 0,06679422 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,04884691 0,06675454 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04884691 0,0667149 ! vesicle targeting GO:0006903 32 23 0,000 0,04884691 0,0666753 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04884691 0,06663576 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04884691 0,06659626 ! osteoblast differentiation GO:0001649 40 23 0,000 0,04884691 0,0665568 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04884691 0,0665174 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04884691 0,06647804 ! interaction with host GO:0051701 37 23 0,000 0,04884691 0,06643872 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04884691 0,06639946 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04884691 0,06636024 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04884691 0,06632106 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04884691 0,06628194 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,04884691 0,06624286 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04884691 0,06620382 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04884691 0,06616483 ! cell fate determination GO:0001709 45 23 0,000 0,04884691 0,06612589 ! pentose metabolic process GO:0019321 31 23 0,000 0,04884691 0,06608699 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04884691 0,06604814 ! spermatid development GO:0007286 33 23 0,000 0,04884691 0,06600933 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04884691 0,06597057 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04884691 0,06593186 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04884691 0,06589319 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04884691 0,06585456 ! telomere organization GO:0032200 32 23 0,000 0,04884691 0,06581598 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04884691 0,06577745 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04884691 0,06573896 ! regulation of amine transport GO:0051952 38 23 0,000 0,04884691 0,06570052 ! liver development GO:0001889 40 23 0,000 0,04884691 0,06566212 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,05091712 0,06840501 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,05091712 0,06836507 ! initiation of viral infection GO:0019059 42 24 0,000 0,05091712 0,06832519 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,05091712 0,06828535 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,05091712 0,06824555 ! superoxide metabolic process GO:0006801 32 24 0,000 0,05091712 0,06820581 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,05091712 0,06816611 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,05091712 0,06812645 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,05091712 0,06808684 ! sperm motility GO:0030317 27 24 0,000 0,05091712 0,06804728 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,05091712 0,06800776 ! vacuole organization GO:0007033 39 24 0,000 0,05091712 0,06796829 ! receptor metabolic process GO:0043112 37 24 0,000 0,05091712 0,06792887 ! neural crest cell development GO:0014032 39 24 0,000 0,05091712 0,06788949 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,05091712 0,06785016 ! primary neural tube formation GO:0014020 35 24 0,000 0,05091712 0,06781087 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,05091712 0,06777163 ! base-excision repair GO:0006284 31 24 0,000 0,05091712 0,06773243 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,05091712 0,06769328 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,05091712 0,06765417 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,05091712 0,06761511 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,05091712 0,06757609 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,05091712 0,06753712 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,05298294 0,07023675 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,05298294 0,07019629 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,05298294 0,07015588 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,05298294 0,07011551 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,05298294 0,07007519 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,05298294 0,07003492 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,05298294 0,06999469 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 43 25 0,000 0,05298294 0,06995451 ! male gonad development GO:0008584 33 25 0,000 0,05298294 0,06991438 ! iron ion homeostasis GO:0055072 39 25 0,000 0,05298294 0,06987429 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,05298294 0,06983425 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,05298294 0,06979425 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,05298294 0,0697543 ! phospholipid transport GO:0015914 35 25 0,000 0,05298294 0,0697144 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,05298294 0,06967454 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,05298294 0,06963472 ! detection of light stimulus GO:0009583 30 25 0,000 0,05298294 0,06959495 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,05298294 0,06955523 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,05298294 0,06951555 ! leukocyte proliferation GO:0070661 39 25 0,000 0,05298294 0,06947592 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,05298294 0,06943633 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,05504439 0,07209686 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,05504439 0,07205583 ! translational initiation GO:0006413 43 26 0,000 0,05504439 0,07201484 ! circadian rhythm GO:0007623 42 26 0,000 0,05504439 0,0719739 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,05504439 0,071933 ! post-embryonic development GO:0009791 42 26 0,000 0,05504439 0,07189216 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,05504439 0,07185135 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,05504439 0,0718106 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,05504439 0,07176989 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,05504439 0,07172923 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,05504439 0,07168861 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,05710146 0,07432561 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,05710146 0,07428358 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,05710146 0,07424158 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,05710146 0,07419964 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,05710146 0,07415774 ! catechol metabolic process GO:0009712 43 27 0,000 0,05710146 0,07411589 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,05710146 0,07407409 ! acute-phase response GO:0006953 42 27 0,000 0,05710146 0,07403233 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,05710146 0,07399063 ! myofibril assembly GO:0030239 36 27 0,000 0,05710146 0,07394896 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,05710146 0,07390735 ! response to ionizing radiation GO:0010212 47 27 0,000 0,05710146 0,07386578 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,05710146 0,07382426 ! natural killer cell activation GO:0030101 35 27 0,000 0,05710146 0,07378279 ! lipid oxidation GO:0034440 38 27 0,000 0,05710146 0,07374136 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,05710146 0,07369998 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,05710146 0,07365864 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,05710146 0,07361736 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,05710146 0,07357611 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,05710146 0,07353492 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,05710146 0,07349377 ! gene silencing GO:0016458 41 27 0,000 0,05710146 0,07345266 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05915418 0,07605065 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05915418 0,07600816 ! phenol metabolic process GO:0018958 44 28 0,000 0,05915418 0,07596572 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05915418 0,07592333 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05915418 0,07588099 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05915418 0,07583869 ! cell junction assembly GO:0034329 56 28 0,000 0,05915418 0,07579644 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05915418 0,07575424 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05915418 0,07571208 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05915418 0,07566997 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,05915418 0,07562791 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05915418 0,07558589 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05915418 0,07554392 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05915418 0,075502 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05915418 0,07546013 ! mesoderm formation GO:0001707 46 28 0,000 0,05915418 0,0754183 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05915418 0,07537651 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05915418 0,07533478 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05915418 0,07529309 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05915418 0,07525144 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05915418 0,07520984 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05915418 0,07516829 ! neural tube formation GO:0001841 41 28 0,000 0,05915418 0,07512678 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05915418 0,07508532 ! placenta development GO:0001890 37 28 0,000 0,05915418 0,07504391 ! regulation of B cell activation GO:0050864 42 28 0,000 0,05915418 0,07500254 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,06120254 0,07755694 ! regulation of innate immune response GO:0045088 38 29 0,000 0,06120254 0,07751423 ! ovulation cycle process GO:0022602 41 29 0,000 0,06120254 0,07747157 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,06120254 0,07742896 ! protein targeting to membrane GO:0006612 53 29 0,000 0,06120254 0,07738639 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,06120254 0,07734387 ! mismatch repair GO:0006298 34 29 0,000 0,06120254 0,0773014 ! muscle cell development GO:0055001 38 29 0,000 0,06120254 0,07725897 ! formation of primary germ layer GO:0001704 48 29 0,000 0,06120254 0,07721659 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,06120254 0,07717426 ! eye morphogenesis GO:0048592 51 29 0,000 0,06120254 0,07713197 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,06120254 0,07708973 ! tissue homeostasis GO:0001894 42 29 0,000 0,06120254 0,07704753 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,06324656 0,07957718 ! organic anion transport GO:0015711 51 30 0,000 0,06324656 0,07953368 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,06324656 0,07949021 ! spliceosome assembly GO:0000245 49 30 0,000 0,06324656 0,0794468 ! spindle organization GO:0007051 37 30 0,000 0,06324656 0,07940343 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,06324656 0,07936012 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,06324656 0,07931684 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,06324656 0,07927362 ! ceramide metabolic process GO:0006672 43 30 0,000 0,06324656 0,07923044 ! ovulation cycle GO:0042698 43 30 0,000 0,06324656 0,07918731 ! hindbrain development GO:0030902 45 30 0,000 0,06324656 0,07914423 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,06324656 0,07910119 ! adult locomotory behavior GO:0008344 47 30 0,000 0,06324656 0,0790582 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,06324656 0,07901526 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,06324656 0,07897236 ! response to heat GO:0009408 41 30 0,000 0,06324656 0,07892951 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,06324656 0,07888671 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,06324656 0,07884395 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,06528625 0,08134256 ! negative regulation of secretion GO:0051048 49 31 0,000 0,06528625 0,08129852 ! glial cell differentiation GO:0010001 55 31 0,000 0,06528625 0,08125453 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,06528625 0,08121059 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,06528625 0,08116669 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,06528625 0,08112284 ! odontogenesis GO:0042476 50 31 0,000 0,06528625 0,08107904 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,06528625 0,08103528 ! segmentation GO:0035282 41 31 0,000 0,06528625 0,08099157 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,06528625 0,08094791 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,06528625 0,0809043 ! metanephros development GO:0001656 58 31 0,000 0,06528625 0,08086073 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,06528625 0,08081721 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,06528625 0,08077374 ! cell fate specification GO:0001708 37 31 0,000 0,06528625 0,08073031 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,06528625 0,08068693 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,06528625 0,0806436 ! RNA modification GO:0009451 40 31 0,000 0,06528625 0,08060031 ! regulation of muscle development GO:0048634 48 32 0,000 0,06732161 0,08306851 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,06732161 0,08302397 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,06732161 0,08297948 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,06732161 0,08293503 ! meiosis I GO:0007127 52 32 0,000 0,06732161 0,08289064 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,06732161 0,08284629 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,06732161 0,08280198 ! peripheral nervous system development GO:0007422 53 32 0,000 0,06732161 0,08275773 ! regulation of protein stability GO:0031647 48 32 0,000 0,06732161 0,08271352 ! cytokine production GO:0001816 44 32 0,000 0,06732161 0,08266936 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,06732161 0,08262525 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,06732161 0,08258118 ! vesicle localization GO:0051648 47 32 0,000 0,06732161 0,08253716 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,06935266 0,08498195 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,06935266 0,0849367 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,06935266 0,08489149 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06935266 0,08484634 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06935266 0,08480123 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06935266 0,08475617 ! ear morphogenesis GO:0042471 42 33 0,000 0,06935266 0,08471116 ! actomyosin structure organization GO:0031032 43 33 0,000 0,06935266 0,0846662 ! cell junction organization GO:0034330 63 33 0,000 0,06935266 0,08462128 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06935266 0,08457641 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06935266 0,08453159 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,06935266 0,08448682 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,06935266 0,0844421 ! female gonad development GO:0008585 49 33 0,000 0,06935266 0,08439742 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06935266 0,08435279 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06935266 0,0843082 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06935266 0,08426367 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,06935266 0,08421918 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06935266 0,08417473 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,06935266 0,08413034 ! cytokinesis GO:0000910 52 33 0,000 0,06935266 0,08408599 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06935266 0,08404169 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,0713794 0,08645214 ! mRNA catabolic process GO:0006402 48 34 0,000 0,0713794 0,08640664 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,0713794 0,08636119 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,0713794 0,08631578 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,0713794 0,08627043 ! feeding behavior GO:0007631 45 34 0,000 0,0713794 0,08622512 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,0713794 0,08617985 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,0713794 0,08613464 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,0713794 0,08608947 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,0713794 0,08604435 ! neuron migration GO:0001764 46 34 0,000 0,0713794 0,08599928 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,0713794 0,08595425 ! female gamete generation GO:0007292 43 34 0,000 0,0713794 0,08590927 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,0713794 0,08586434 ! polyol metabolic process GO:0019751 44 34 0,000 0,0713794 0,08581946 ! aerobic respiration GO:0009060 47 34 0,000 0,0713794 0,08577462 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,0713794 0,08572983 ! embryonic organ development GO:0048568 45 34 0,000 0,0713794 0,08568508 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,0713794 0,08564039 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,07340184 0,08802098 ! Notch signaling pathway GO:0007219 56 35 0,000 0,07340184 0,08797511 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,07340184 0,08792929 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,07340184 0,08788352 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,07340184 0,08783779 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,07340184 0,08779212 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,07340184 0,08774649 ! maintenance of protein location GO:0045185 65 35 0,000 0,07340184 0,0877009 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,07340184 0,08765537 ! glycogen metabolic process GO:0005977 48 35 0,000 0,07340184 0,08760988 ! pigment metabolic process GO:0042440 61 35 0,000 0,07340184 0,08756444 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,07340184 0,08751905 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,07542 0,08987875 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,07542 0,08983221 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,07542 0,08978571 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,07542 0,08973926 ! negative regulation of binding GO:0051100 58 36 0,000 0,07542 0,08969286 ! neural tube development GO:0021915 50 36 0,000 0,07542 0,08964651 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,07542 0,0896002 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,07542 0,08955395 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,07542 0,08950774 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,07542 0,08946158 ! glucan metabolic process GO:0044042 49 36 0,000 0,07542 0,08941546 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,07743387 0,09175575 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,07743387 0,0917085 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,07743387 0,0916613 ! learning GO:0007612 67 37 0,000 0,07743387 0,09161415 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,07743387 0,09156705 ! regulation of protein secretion GO:0050708 51 37 0,000 0,07743387 0,09151999 ! amino acid activation GO:0043038 52 37 0,000 0,07743387 0,09147299 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,07743387 0,09142603 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,07944347 0,09375064 ! gliogenesis GO:0042063 71 38 0,000 0,07944347 0,09370256 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,07944347 0,09365453 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,07944347 0,09360655 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,07944347 0,09355862 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,07944347 0,09351074 ! phagocytosis GO:0006909 60 38 0,000 0,07944347 0,09346291 ! mesenchymal cell development GO:0014031 64 38 0,000 0,07944347 0,09341513 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,07944347 0,09336739 ! maintenance of location in cell GO:0051651 69 38 0,000 0,07944347 0,09331971 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,08144881 0,09562648 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,08144881 0,09557769 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,08144881 0,09552895 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,08144881 0,09548026 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,08144881 0,09543162 ! male sex differentiation GO:0046661 53 39 0,000 0,08144881 0,09538303 ! chromatin remodeling GO:0006338 68 39 0,000 0,08144881 0,09533449 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,08144881 0,095286 ! JNK cascade GO:0007254 54 39 0,000 0,08144881 0,09523756 ! developmental growth GO:0048589 62 39 0,000 0,08144881 0,09518916 ! synapse organization GO:0050808 55 39 0,000 0,08144881 0,09514082 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,0834499 0,09742882 ! response to calcium ion GO:0051592 58 40 0,000 0,0834499 0,09737939 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,0834499 0,09733 ! regulation of tube size GO:0035150 60 40 0,000 0,0834499 0,09728067 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,0834499 0,09723139 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,0834499 0,09718216 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,0834499 0,09713298 ! peptide metabolic process GO:0006518 56 40 0,000 0,0834499 0,09708385 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,0834499 0,09703477 ! inner ear development GO:0048839 57 40 0,000 0,0834499 0,09698573 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,0834499 0,09693675 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,0834499 0,09688782 ! B cell differentiation GO:0030183 62 40 0,000 0,0834499 0,09683893 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,0834499 0,0967901 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,0834499 0,09674132 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,0834499 0,09669258 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,08544674 0,09895645 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,08544674 0,09890665 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,08544674 0,09885689 ! glucose transport GO:0015758 52 41 0,000 0,08544674 0,09880719 ! endosome transport GO:0016197 71 41 0,000 0,08544674 0,09875754 ! striated muscle contraction GO:0006941 62 41 0,000 0,08544674 0,09870794 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,08544674 0,09865839 ! biopolymer methylation GO:0043414 62 41 0,000 0,08544674 0,09860888 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,08544674 0,09855943 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,08743935 0,10080727 ! cellular component disassembly GO:0022411 64 42 0,000 0,08743935 0,10075676 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,08743935 0,10070631 ! hexose transport GO:0008645 54 42 0,000 0,08743935 0,1006559 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,08743935 0,10060555 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,08743935 0,10055525 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,08743935 0,100505 ! excretion GO:0007588 63 42 0,000 0,08743935 0,10045479 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,08743935 0,10040464 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,08743935 0,10035454 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,08743935 0,10030449 ! regulation of cell shape GO:0008360 78 42 0,000 0,08743935 0,10025448 ! positive regulation of binding GO:0051099 59 43 0,000 0,08942772 0,10248319 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,08942772 0,10243215 ! leukocyte migration GO:0050900 60 43 0,000 0,08942772 0,10238117 ! neuromuscular process GO:0050905 79 43 0,000 0,08942772 0,10233023 ! activation of caspase activity GO:0006919 65 43 0,000 0,08942772 0,10227935 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,08942772 0,10222851 ! tRNA processing GO:0008033 49 43 0,000 0,08942772 0,10217773 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,08942772 0,10212699 ! methylation GO:0032259 64 43 0,000 0,08942772 0,10207631 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,09141188 0,10428935 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,09141188 0,10423764 ! glycolysis GO:0006096 53 44 0,000 0,09141188 0,10418599 ! regulation of action potential GO:0001508 71 44 0,000 0,09141188 0,10413439 ! regulation of ion transport GO:0043269 57 44 0,000 0,09141188 0,10408284 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,09141188 0,10403134 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,09141188 0,10397989 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,09141188 0,10392849 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,09141188 0,10387714 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,09141188 0,10382584 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,09141188 0,10377459 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,09141188 0,1037234 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,09141188 0,10367225 ! RNA catabolic process GO:0006401 64 45 0,000 0,09339183 0,10586556 ! positive regulation of defense response GO:0031349 59 45 0,000 0,09339183 0,1058134 ! regulation of translational initiation GO:0006446 64 45 0,000 0,09339183 0,10576131 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,09339183 0,10570926 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,09339183 0,10565726 ! cell recognition GO:0008037 58 45 0,000 0,09339183 0,10560532 ! cell maturation GO:0048469 60 45 0,000 0,09339183 0,10555342 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,09536758 0,10773351 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,09536758 0,10768062 ! cell redox homeostasis GO:0045454 63 46 0,000 0,09536758 0,10762779 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,09536758 0,107575 ! regulation of ossification GO:0030278 71 46 0,000 0,09536758 0,10752227 ! histone modification GO:0016570 68 46 0,000 0,09536758 0,10746959 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,09733913 0,10963761 ! viral infectious cycle GO:0019058 71 47 0,000 0,09733913 0,10958395 ! endocrine system development GO:0035270 83 47 0,000 0,09733913 0,10953034 ! covalent chromatin modification GO:0016569 75 47 0,000 0,09733913 0,10947678 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,09733913 0,10942327 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,09733913 0,10936981 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,09733913 0,10931641 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,09733913 0,10926306 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,09733913 0,10920976 ! chloride transport GO:0006821 67 48 0,000 0,0993065 0,11136273 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,0993065 0,11130846 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,0993065 0,11125424 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,0993065 0,11120008 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,0993065 0,11114597 ! gastrulation GO:0007369 73 48 0,000 0,0993065 0,11109191 ! heart morphogenesis GO:0003007 65 48 0,000 0,0993065 0,1110379 ! regulation of DNA replication GO:0006275 75 48 0,000 0,0993065 0,11098395 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,0993065 0,11093004 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,0993065 0,11087619 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,0993065 0,1108224 ! regulation of endocytosis GO:0030100 63 48 0,000 0,0993065 0,11076865 ! nuclear export GO:0051168 69 48 0,000 0,0993065 0,11071496 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,0993065 0,11066132 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,1012697 0,11279434 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,1012697 0,11273974 ! sensory perception of smell GO:0007608 61 49 0,000 0,1012697 0,1126852 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,1012697 0,11263071 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,1012697 0,11257627 ! RNA elongation GO:0006354 62 49 0,000 0,1012697 0,11252189 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,1012697 0,11246756 ! germ cell development GO:0007281 68 49 0,000 0,1012697 0,11241328 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,1012697 0,11235905 ! maintenance of location GO:0051235 84 49 0,000 0,1012697 0,11230487 ! regulation of actin filament length GO:0030832 72 50 0,000 0,10322873 0,11442221 ! ear development GO:0043583 72 50 0,000 0,10322873 0,11436709 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,10322873 0,11431203 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,10322873 0,11425701 ! positive regulation of growth GO:0045927 67 50 0,000 0,10322873 0,11420206 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,10322873 0,11414715 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,10322873 0,1140923 ! positive regulation of secretion GO:0051047 71 51 0,000 0,1051836 0,11619706 ! muscle fiber development GO:0048747 74 51 0,000 0,1051836 0,11614128 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,1051836 0,11608555 ! adult behavior GO:0030534 80 51 0,000 0,1051836 0,11602987 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,1051836 0,11597425 ! transition metal ion transport GO:0000041 74 52 0,000 0,10713432 0,11806849 ! regulation of cellular component size GO:0032535 74 52 0,000 0,10713432 0,11801194 ! aging GO:0007568 79 52 0,000 0,10713432 0,11795545 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,10713432 0,11789901 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,10713432 0,11784263 ! establishment of organelle localization GO:0051656 85 52 0,000 0,10713432 0,1177863 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,1090809 0,11986912 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,1090809 0,11981188 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,1090809 0,11975469 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,1090809 0,11969755 ! kidney development GO:0001822 90 53 0,000 0,1090809 0,11964047 ! single fertilization GO:0007338 59 53 0,000 0,1090809 0,11958345 ! cell projection assembly GO:0030031 76 53 0,000 0,1090809 0,11952648 ! amino acid transport GO:0006865 84 54 0,000 0,11102335 0,121597 ! regulation of mitosis GO:0007088 84 54 0,000 0,11102335 0,12153913 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,11102335 0,12148131 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,11102335 0,12142354 ! DNA catabolic process GO:0006308 67 54 0,000 0,11102335 0,12136583 ! detection of external stimulus GO:0009581 66 54 0,000 0,11102335 0,12130817 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,11102335 0,12125057 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,11102335 0,12119303 ! exocytosis GO:0006887 74 55 0,000 0,11296167 0,1232504 ! mesoderm development GO:0007498 76 55 0,000 0,11296167 0,12319196 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,11296167 0,12313358 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,11296167 0,12307525 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,11489588 0,12512336 ! carbohydrate transport GO:0008643 74 57 0,000 0,11682598 0,12716506 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,11682598 0,1271049 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,11682598 0,12704481 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,11682598 0,12698477 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,11682598 0,12692478 ! camera-type eye development GO:0043010 88 57 0,000 0,11682598 0,12686486 ! secondary metabolic process GO:0019748 84 57 0,000 0,11682598 0,12680499 ! gonad development GO:0008406 79 57 0,000 0,11682598 0,12674517 ! viral reproductive process GO:0022415 87 58 0,000 0,11875199 0,12877396 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,11875199 0,12871328 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,11875199 0,12865265 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,11875199 0,12859208 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,1206739 0,13061175 ! activation of MAPK activity GO:0000187 84 59 0,000 0,1206739 0,13055032 ! lung development GO:0030324 94 59 0,000 0,1206739 0,13048894 ! actin filament organization GO:0007015 95 59 0,000 0,1206739 0,13042762 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,1206739 0,13036636 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,1206739 0,13030515 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,12259173 0,13231393 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,12259173 0,13225187 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,12259173 0,13218987 ! regulation of heart contraction GO:0008016 91 60 0,000 0,12259173 0,13212792 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,12259173 0,13206604 ! fertilization GO:0009566 68 60 0,000 0,12259173 0,13200421 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,12259173 0,13194244 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,12450549 0,13393949 ! meiosis GO:0007126 96 61 0,000 0,12450549 0,13387687 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,12450549 0,13381432 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,12450549 0,13375181 ! urogenital system development GO:0001655 101 61 0,000 0,12450549 0,13368937 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,12450549 0,13362699 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,12450549 0,13356466 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,12450549 0,13350239 ! amine catabolic process GO:0009310 90 62 0,000 0,12641519 0,13548692 ! neurotransmitter transport GO:0006836 81 62 0,000 0,12641519 0,13542382 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,12641519 0,13536077 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,12641519 0,13529778 ! respiratory tube development GO:0030323 99 62 0,000 0,12641519 0,13523485 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,12641519 0,13517198 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,12641519 0,13510917 ! meiotic cell cycle GO:0051321 97 62 0,000 0,12641519 0,13504642 ! organelle localization GO:0051640 96 62 0,000 0,12641519 0,13498372 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,12832083 0,13695494 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,12832083 0,13689142 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,12832083 0,13682796 ! viral reproduction GO:0016032 92 63 0,000 0,12832083 0,13676455 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,13022242 0,13872698 ! negative regulation of cell size GO:0045792 108 64 0,000 0,13022242 0,13866276 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,13022242 0,13859859 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,13022242 0,13853449 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,13022242 0,13847044 ! hexose catabolic process GO:0019320 82 64 0,000 0,13022242 0,13840645 ! respiratory system development GO:0060541 100 64 0,000 0,13022242 0,13834252 ! adaptive immune response GO:0002250 94 64 0,000 0,13022242 0,13827865 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,13211997 0,14022885 ! B cell activation GO:0042113 104 65 0,000 0,13211997 0,14016417 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,13211997 0,14009955 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,13211997 0,14003499 ! defense response to bacterium GO:0042742 73 65 0,000 0,13211997 0,13997049 ! activation of immune response GO:0002253 83 65 0,000 0,13211997 0,13990604 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,13401349 0,14184585 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,13401349 0,1417806 ! antigen processing and presentation GO:0019882 96 66 0,000 0,13401349 0,14171541 ! axon guidance GO:0007411 99 66 0,000 0,13401349 0,14165029 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,13401349 0,14158522 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,13590299 0,14351555 ! acute inflammatory response GO:0002526 92 68 0,000 0,13778847 0,14543987 ! learning or memory GO:0007611 123 68 0,000 0,13778847 0,14537316 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,13778847 0,1453065 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,13778847 0,14523991 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,13778847 0,14517338 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,13778847 0,1451069 ! rhythmic process GO:0048511 105 68 0,000 0,13778847 0,14504049 ! inorganic anion transport GO:0015698 93 68 0,000 0,13778847 0,14497414 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,13966995 0,14688655 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,13966995 0,14681941 ! response to drug GO:0042493 108 69 0,000 0,13966995 0,14675234 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,13966995 0,14668533 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,14154743 0,14858926 ! humoral immune response GO:0006959 86 70 0,000 0,14154743 0,14852148 ! eye development GO:0001654 111 70 0,000 0,14154743 0,14845375 ! amine transport GO:0015837 101 70 0,000 0,14154743 0,14838609 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,14154743 0,14831849 ! regulation of catabolic process GO:0009894 106 70 0,000 0,14154743 0,14825095 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,14342091 0,15014479 ! muscle cell differentiation GO:0042692 104 71 0,000 0,14342091 0,15007648 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,14342091 0,15000823 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,14342091 0,14994005 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,14342091 0,14987192 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,14342091 0,14980386 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,14529042 0,15168769 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,14529042 0,15161886 ! negative regulation of transport GO:0051051 116 73 0,000 0,14715596 0,15349601 ! regulation of blood pressure GO:0008217 107 73 0,000 0,14715596 0,15342643 ! tube morphogenesis GO:0035239 118 73 0,000 0,14715596 0,15335691 ! mitochondrion organization GO:0007005 104 73 0,000 0,14715596 0,15328746 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,14715596 0,15321806 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,14901753 0,15508611 ! digestion GO:0007586 97 74 0,000 0,14901753 0,15501597 ! protein import into nucleus GO:0006606 118 74 0,000 0,14901753 0,15494589 ! blood coagulation GO:0007596 116 75 0,000 0,15087514 0,15680652 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,15087514 0,15673569 ! response to nutrient GO:0007584 104 75 0,000 0,15087514 0,15666493 ! regulation of ligase activity GO:0051340 114 75 0,000 0,15087514 0,15659423 ! nuclear import GO:0051170 121 75 0,000 0,15087514 0,1565236 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,15087514 0,15645303 ! amine biosynthetic process GO:0009309 97 76 0,000 0,15272881 0,15830385 ! tRNA metabolic process GO:0006399 95 76 0,000 0,15272881 0,15823255 ! response to unfolded protein GO:0006986 99 76 0,000 0,15272881 0,1581613 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,15272881 0,15809012 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,15457853 0,1599328 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,15457853 0,15986089 ! regulation of DNA binding GO:0051101 119 77 0,000 0,15457853 0,15978904 ! sex differentiation GO:0007548 105 77 0,000 0,15457853 0,15971726 ! protein ubiquitination GO:0016567 125 77 0,000 0,15457853 0,15964554 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,15457853 0,15957389 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,15457853 0,1595023 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,15457853 0,15943077 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,15642432 0,16126219 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,15642432 0,16118994 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,15642432 0,16111775 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,15826619 0,16294192 ! cellular respiration GO:0045333 107 79 0,000 0,15826619 0,16286901 ! regulation of lyase activity GO:0051339 133 79 0,000 0,15826619 0,16279617 ! chromatin assembly GO:0031497 102 80 0,000 0,16010414 0,16461311 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,16010414 0,16453956 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,16010414 0,16446607 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,16010414 0,16439265 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,16010414 0,16431929 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,16193819 0,16612749 ! hemostasis GO:0007599 125 81 0,000 0,16193819 0,16605342 ! mRNA transport GO:0051028 121 81 0,000 0,16193819 0,16597943 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,16193819 0,16590549 ! response to protein stimulus GO:0051789 111 81 0,000 0,16193819 0,16583163 ! regulation of neurological system process GO:0031644 122 81 0,000 0,16193819 0,16575782 ! vitamin metabolic process GO:0006766 103 81 0,000 0,16193819 0,16568409 ! detection of stimulus GO:0051606 108 82 0,000 0,16376833 0,16748207 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,16559459 0,16927447 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,16559459 0,16919927 ! regulation of defense response GO:0031347 117 84 0,000 0,16741696 0,17098534 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,16741696 0,17090945 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,16741696 0,17083363 ! sterol metabolic process GO:0016125 120 84 0,000 0,16741696 0,17075787 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,16923545 0,17253614 ! rRNA metabolic process GO:0016072 107 85 0,000 0,16923545 0,1724597 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,16923545 0,17238332 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,16923545 0,17230701 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,17105008 0,17407751 ! cell cycle arrest GO:0007050 150 86 0,000 0,17105008 0,17400052 ! nucleosome organization GO:0034728 114 87 0,000 0,17286084 0,17576478 ! cellular defense response GO:0006968 102 87 0,000 0,17286084 0,17568711 ! female pregnancy GO:0007565 130 87 0,000 0,17286084 0,17560951 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,17286084 0,17553198 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,17466776 0,17728854 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,17466776 0,17721034 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,17466776 0,17713221 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,17466776 0,17705414 ! reproductive developmental process GO:0003006 127 89 0,000 0,17647083 0,17880304 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,17647083 0,17872431 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,17827006 0,18046705 ! hormone metabolic process GO:0042445 121 90 0,000 0,17827006 0,18038766 ! RNA localization GO:0006403 135 91 0,000 0,18006547 0,18212427 ! response to virus GO:0009615 122 91 0,000 0,18006547 0,18204421 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,18185706 0,18377471 ! cell fate commitment GO:0045165 141 92 0,000 0,18185706 0,183694 ! positive regulation of immune response GO:0050778 121 92 0,000 0,18185706 0,18361336 ! DNA recombination GO:0006310 146 92 0,000 0,18185706 0,18353279 ! sulfur metabolic process GO:0006790 118 92 0,000 0,18185706 0,1834523 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,18364484 0,18517454 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,18364484 0,18509339 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,18364484 0,18501232 ! electron transport chain GO:0022900 123 94 0,000 0,18542881 0,18672779 ! response to oxidative stress GO:0006979 141 94 0,000 0,18542881 0,18664607 ! regulation of binding GO:0051098 151 95 0,000 0,18720899 0,1883555 ! carboxylic acid transport GO:0046942 147 95 0,000 0,18720899 0,18827314 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,18898537 0,18997656 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,18898537 0,18989356 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,18898537 0,18981064 ! protein maturation GO:0051604 129 96 0,000 0,18898537 0,18972779 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,19075798 0,1914238 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,19075798 0,19134032 ! protein import GO:0017038 156 99 0,000 0,19429189 0,19480006 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,19429189 0,19471518 ! regulation of translation GO:0006417 151 100 0,000 0,1960532 0,19639476 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,1960532 0,19630926 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,1960532 0,19622383 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,1960532 0,19613848 ! protein localization in organelle GO:0033365 161 100 0,000 0,1960532 0,1960532