pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1252-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phosphoinositide 3-kinase cascade GO:0014065 29 8 3,000 2,04E-10 4,984E-07 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 3,000 3,048E-08 3,724E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,93E-07 1,572E-04 ! branching morphogenesis of a tube GO:0048754 102 45 3,000 4,187E-07 2,557E-04 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 4,187E-07 2,046E-04 ! positive regulation of cell cycle GO:0045787 96 48 3,000 5,451E-07 2,22E-04 ! morphogenesis of a branching structure GO:0001763 116 52 3,000 7,554E-07 2,636E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 2,000 8,325E-07 2,542E-04 GO:0060675|ureteric bud morphogenesis, ! positive regulation of cell migration GO:0030335 137 58 3,000 1,177E-06 3,195E-04 ! positive regulation of cell motion GO:0051272 157 65 3,000 1,865E-06 4,556E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 2,593E-06 5,758E-04 ! ureteric bud development GO:0001657 50 22 2,000 3,496E-06 7,116E-04 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 3,496E-06 6,569E-04 ! positive regulation of nuclear division GO:0051785 41 26 2,000 5,879E-06 1,026E-03 GO:0045840|positive regulation of mitosis, ! tube morphogenesis GO:0035239 194 89 3,000 6,568E-06 1,07E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 6,608E-06 1,009E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 8,239E-06 1,184E-03 ! metanephros development GO:0001656 81 32 2,000 1,115E-05 1,514E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,781E-05 2,29E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,781E-05 2,176E-03 ! skeletal muscle regeneration GO:0043403 8 5 1,000 1,781E-05 2,072E-03 ! regulation of muscle cell apoptosis GO:0010660 7 5 1,000 1,781E-05 1,978E-03 ! somatic stem cell maintenance GO:0035019 15 5 1,000 1,781E-05 1,892E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,781E-05 1,813E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,886E-05 1,843E-03 ! mammary gland development GO:0030879 93 40 2,000 2,205E-05 2,072E-03 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 2,557E-05 2,313E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 3,368E-05 2,939E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 3,368E-05 2,837E-03 ! positive regulation of protein transport GO:0051222 80 46 2,000 3,368E-05 2,743E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 3,594E-05 2,833E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,734E-05 2,851E-03 ! regulation of granule cell precursor proliferation GO:0021936 12 7 1,000 3,734E-05 2,764E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! muscle adaptation GO:0043500 13 7 1,000 3,734E-05 2,683E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,974E-05 3,472E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 4,974E-05 3,376E-03 ! ER overload response GO:0006983 13 8 1,000 4,974E-05 3,284E-03 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 5,462E-05 3,511E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 6,39E-05 4,003E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 6,39E-05 3,903E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 20 9 1,000 6,39E-05 3,807E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 6,39E-05 3,717E-03 ! regulation of intracellular transport GO:0032386 108 57 2,000 6,425E-05 3,65E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 6,769E-05 3,758E-03 ! kidney development GO:0001822 133 60 2,000 7,492E-05 4,068E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 7,981E-05 4,238E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 7,981E-05 4,148E-03 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 7,981E-05 4,062E-03 ! multicellular organism growth GO:0035264 19 10 1,000 7,981E-05 3,979E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 7,981E-05 3,899E-03 GO:0045685|regulation of glial cell differentiation, ! induction of an organ GO:0001759 17 10 1,000 7,981E-05 3,823E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 7,981E-05 3,749E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 7,981E-05 3,679E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of mitosis GO:0007088 112 63 2,000 8,67E-05 3,922E-03 GO:0051783|regulation of nuclear division, ! response to peptide hormone stimulus GO:0043434 129 64 2,000 9,088E-05 4,037E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 9,746E-05 4,252E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 9,746E-05 4,177E-03 ! cardiac cell differentiation GO:0035051 36 11 1,000 9,746E-05 4,105E-03 ! urogenital system development GO:0001655 149 69 2,000 1,137E-04 4,71E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 1,137E-04 4,631E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,168E-04 4,68E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,168E-04 4,604E-03 ! developmental induction GO:0031128 22 12 1,000 1,168E-04 4,531E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 1,168E-04 4,46E-03 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 1,000 1,38E-04 5,186E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,38E-04 5,107E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,38E-04 5,031E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 1,608E-04 5,778E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! myotube differentiation GO:0014902 26 14 1,000 1,608E-04 5,694E-03 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 1,000 1,608E-04 5,613E-03 ! positive regulation of bone mineralization GO:0030501 32 14 1,000 1,608E-04 5,534E-03 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 1,831E-04 6,214E-03 ! positive regulation of biomineral formation GO:0070169 33 15 1,000 1,854E-04 6,205E-03 ! water homeostasis GO:0030104 28 15 1,000 1,854E-04 6,121E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 1,854E-04 6,039E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 1,968E-04 6,327E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 182 85 2,000 2,112E-04 6,701E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,117E-04 6,631E-03 ! heterophilic cell adhesion GO:0007157 43 16 1,000 2,117E-04 6,547E-03 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 1,000 2,117E-04 6,465E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 2,117E-04 6,385E-03 ! stem cell development GO:0048864 46 16 1,000 2,117E-04 6,308E-03 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,117E-04 6,232E-03 ! tissue regeneration GO:0042246 27 16 1,000 2,117E-04 6,157E-03 ! regulation of protein transport GO:0051223 165 87 2,000 2,262E-04 6,502E-03 GO:0070201|regulation of establishment of protein localization, ! myoblast differentiation GO:0045445 50 17 1,000 2,397E-04 6,81E-03 ! regulation of cell cycle process GO:0010564 161 90 2,000 2,5E-04 7,021E-03 ! gland development GO:0048732 220 91 2,000 2,583E-04 7,171E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 2,695E-04 7,397E-03 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 2,695E-04 7,315E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 2,695E-04 7,234E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 2,695E-04 7,156E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 2,754E-04 7,234E-03 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 3,009E-04 7,821E-03 ! proximal/distal pattern formation GO:0009954 33 19 1,000 3,009E-04 7,738E-03 ! regulation of protein localization GO:0032880 188 97 2,000 3,117E-04 7,932E-03 ! positive regulation of ossification GO:0045778 50 20 1,000 3,341E-04 8,414E-03 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,341E-04 8,328E-03 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 3,341E-04 8,244E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 3,341E-04 8,161E-03 ! lipid phosphorylation GO:0046834 43 21 1,000 3,689E-04 8,923E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 3,689E-04 8,836E-03 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 3,689E-04 8,75E-03 ! positive regulation of bone remodeling GO:0046852 54 22 1,000 4,055E-04 9,524E-03 GO:0034105|positive regulation of tissue remodeling, ! stem cell differentiation GO:0048863 57 22 1,000 4,055E-04 9,434E-03 ! peptidyl-serine modification GO:0018209 50 22 1,000 4,055E-04 9,345E-03 ! positive regulation of DNA replication GO:0045740 44 23 1,000 4,437E-04 0,01013009 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 4,437E-04 0,01003629 ! regeneration GO:0031099 42 23 1,000 4,437E-04 9,944E-03 ! regulation of bone mineralization GO:0030500 54 23 1,000 4,437E-04 9,854E-03 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 4,836E-04 0,0106436 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 4,836E-04 0,01054856 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 4,836E-04 0,01045521 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 5,252E-04 0,01125497 ! regulation of biomineral formation GO:0070167 56 25 1,000 5,252E-04 0,01115711 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 5,685E-04 0,01197235 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 5,685E-04 0,01187002 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 5,685E-04 0,01176943 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 6,134E-04 0,01259331 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 6,6E-04 0,01343743 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 6,6E-04 0,01332638 ! proteoglycan biosynthetic process GO:0030166 62 28 1,000 6,6E-04 0,01321715 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 7,083E-04 0,01406866 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 7,083E-04 0,0139552 ! synaptogenesis GO:0007416 46 29 1,000 7,083E-04 0,01384356 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 8,631E-04 0,01673482 ! BMP signaling pathway GO:0030509 71 32 1,000 8,631E-04 0,01660305 ! positive regulation of catabolic process GO:0009896 72 32 1,000 8,631E-04 0,01647334 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 9,18E-04 0,01738522 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 9,18E-04 0,01725149 ! glial cell differentiation GO:0010001 67 34 1,000 9,745E-04 0,01817413 ! cell fate specification GO:0001708 56 34 1,000 9,745E-04 0,01803645 ! proteoglycan metabolic process GO:0006029 75 35 1,000 1,033E-03 0,0189694 ! calcium-mediated signaling GO:0019722 67 35 1,000 1,033E-03 0,01882784 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 1,093E-03 0,01977066 ! positive regulation of cell development GO:0010720 85 36 1,000 1,093E-03 0,01962529 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 1,154E-03 0,02057758 ! odontogenesis GO:0042476 74 37 1,000 1,154E-03 0,02042847 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 1,217E-03 0,02138984 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 1,217E-03 0,02123705 ! glycogen metabolic process GO:0005977 63 38 1,000 1,217E-03 0,02108644 ! glucan metabolic process GO:0044042 64 39 1,000 1,282E-03 0,02205074 GO:0006073|cellular glucan metabolic process, ! gliogenesis GO:0042063 91 41 1,000 1,416E-03 0,02418933 ! mesenchymal cell development GO:0014031 94 41 1,000 1,416E-03 0,02402134 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 1,485E-03 0,02502693 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 1,557E-03 0,02604556 ! energy reserve metabolic process GO:0006112 76 44 1,000 1,629E-03 0,02707691 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 1,629E-03 0,02689395 ! developmental growth GO:0048589 88 45 1,000 1,704E-03 0,02793191 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 1,779E-03 0,02898193 ! cell growth GO:0016049 90 46 1,000 1,779E-03 0,02879 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 1,936E-03 0,03111694 ! protein homooligomerization GO:0051260 84 49 1,000 2,017E-03 0,03220134 ! regulation of ossification GO:0030278 123 50 1,000 2,099E-03 0,03329661 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 2,355E-03 0,03711781 ! cartilage development GO:0051216 99 53 1,000 2,355E-03 0,03687988 ! synapse organization GO:0050808 102 53 1,000 2,355E-03 0,03664498 ! activation of phospholipase C activity GO:0007202 110 54 1,000 2,443E-03 0,03778107 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 2,534E-03 0,03892672 ! response to UV GO:0009411 120 55 1,000 2,534E-03 0,03868343 ! skeletal muscle fiber development GO:0048741 130 56 1,000 2,625E-03 0,03983274 ! regulation of DNA replication GO:0006275 105 56 1,000 2,625E-03 0,03958686 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 2,718E-03 0,04073967 ! regulation of bone remodeling GO:0046850 143 57 1,000 2,718E-03 0,04049126 ! muscle fiber development GO:0048747 131 57 1,000 2,718E-03 0,04024586 ! regulation of phospholipase activity GO:0010517 113 57 1,000 2,718E-03 0,04000341 ! heart morphogenesis GO:0003007 105 57 1,000 2,718E-03 0,03976387 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 2,813E-03 0,04090371 ! sulfur compound biosynthetic process GO:0044272 108 58 1,000 2,813E-03 0,04066168 ! regulation of tissue remodeling GO:0034103 146 58 1,000 2,813E-03 0,04042249 ! positive regulation of lipase activity GO:0060193 115 58 1,000 2,813E-03 0,0401861 ! lipid modification GO:0030258 112 60 1,000 3,007E-03 0,04270689 ! mesoderm development GO:0007498 128 63 1,000 3,309E-03 0,04672942 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 3,413E-03 0,04791844 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 3,625E-03 0,05060635 ! activation of MAPK activity GO:0000187 124 67 1,000 3,733E-03 0,05182258 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 3,733E-03 0,0515298 GO:0035113|embryonic appendage morphogenesis, ! regulation of lipase activity GO:0060191 137 68 1,000 3,843E-03 0,05274775 ! lung development GO:0030324 165 69 1,000 3,955E-03 0,05397249 ! appendage morphogenesis GO:0035107 150 72 1,000 4,298E-03 0,05832677 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 4,298E-03 0,05800452 ! appendage development GO:0048736 151 73 1,000 4,415E-03 0,05925991 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 4,534E-03 0,06052126 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 4,534E-03 0,06019234 ! respiratory system development GO:0060541 175 74 1,000 4,534E-03 0,05986698 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 4,654E-03 0,06112403 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 4,899E-03 0,06399554 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 4,899E-03 0,06365514 ! regulation of catabolic process GO:0009894 173 77 1,000 4,899E-03 0,06331834 ! protein oligomerization GO:0051259 149 79 1,000 5,149E-03 0,06620798 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 5,277E-03 0,0674922 ! muscle cell differentiation GO:0042692 178 81 1,000 5,406E-03 0,06878146 ! regulation of peptidase activity GO:0052547 150 82 1,000 5,536E-03 0,07007561 ! positive regulation of protein modification process GO:0031401 156 90 1,000 6,631E-03 0,08349858 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 6,734E-03 0,08436945 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 6,734E-03 0,08393899 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 6,734E-03 0,0835129 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,734E-03 0,08309112 ! positive regulation of helicase activity GO:0051096 12 5 0,000 6,734E-03 0,08267358 ! neuron fate determination GO:0048664 7 5 0,000 6,734E-03 0,08226021 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,734E-03 0,08185095 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 6,734E-03 0,08144575 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 6,734E-03 0,08104454 ! polyol transport GO:0015791 12 5 0,000 6,734E-03 0,08064726 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,734E-03 0,08025386 ! response to superoxide GO:0000303 10 5 0,000 6,734E-03 0,07986428 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,734E-03 0,07947846 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 6,734E-03 0,07909635 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 6,734E-03 0,0787179 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,734E-03 0,07834306 ! female meiosis GO:0007143 10 5 0,000 6,734E-03 0,07797176 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,734E-03 0,07760397 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,734E-03 0,07723963 ! hypothalamus development GO:0021854 9 5 0,000 6,734E-03 0,0768787 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 6,734E-03 0,07652112 ! cobalt ion transport GO:0006824 11 5 0,000 6,734E-03 0,07616686 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 6,734E-03 0,07581586 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 6,734E-03 0,07546808 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,734E-03 0,07512348 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,734E-03 0,07478201 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 6,734E-03 0,07444363 ! embryonic camera-type eye development GO:0031076 12 5 0,000 6,734E-03 0,0741083 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,734E-03 0,07377597 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,734E-03 0,07344662 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 6,734E-03 0,07312019 ! transposition GO:0032196 9 5 0,000 6,734E-03 0,07279665 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 6,734E-03 0,07247596 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 6,734E-03 0,07215808 ! negative chemotaxis GO:0050919 16 5 0,000 6,734E-03 0,07184298 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,734E-03 0,07153062 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,734E-03 0,07122096 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 6,734E-03 0,07091397 ! behavioral response to pain GO:0048266 10 5 0,000 6,734E-03 0,07060962 ! clathrin coat assembly GO:0048268 15 5 0,000 6,734E-03 0,07030787 ! Notch receptor processing GO:0007220 11 5 0,000 6,734E-03 0,07000869 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,734E-03 0,06971204 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 6,734E-03 0,0694179 ! micturition GO:0060073 9 5 0,000 6,734E-03 0,06912623 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,734E-03 0,068837 ! copulation GO:0007620 9 5 0,000 6,734E-03 0,06855017 ! glial cell fate commitment GO:0021781 14 5 0,000 6,734E-03 0,06826573 ! protein maturation by protein folding GO:0022417 14 5 0,000 6,734E-03 0,06798364 ! bioluminescence GO:0008218 9 5 0,000 6,734E-03 0,06770388 ! spermidine metabolic process GO:0008216 7 5 0,000 6,734E-03 0,0674264 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,734E-03 0,06715119 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,734E-03 0,06687822 ! apoptotic cell clearance GO:0043277 23 5 0,000 6,734E-03 0,06660746 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,734E-03 0,06633888 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 6,734E-03 0,06607246 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,734E-03 0,06580817 ! grooming behavior GO:0007625 6 5 0,000 6,734E-03 0,06554598 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 6,734E-03 0,06528588 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,734E-03 0,06502783 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 6,734E-03 0,06477182 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,734E-03 0,06451781 ! response to protozoan GO:0001562 13 5 0,000 6,734E-03 0,06426579 ! lymph vessel development GO:0001945 10 5 0,000 6,734E-03 0,06401573 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 6,734E-03 0,0637676 ! endochondral ossification GO:0001958 17 5 0,000 6,734E-03 0,0635214 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,734E-03 0,06327708 ! single strand break repair GO:0000012 8 5 0,000 6,734E-03 0,06303464 ! parathyroid gland development GO:0060017 14 5 0,000 6,734E-03 0,06279405 ! anagen GO:0042640 7 5 0,000 6,734E-03 0,06255529 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,734E-03 0,06231834 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,734E-03 0,06208318 ! cytokine secretion GO:0050663 15 5 0,000 6,734E-03 0,06184978 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 6,734E-03 0,06161813 ! ceramide catabolic process GO:0046514 7 5 0,000 6,734E-03 0,06138822 ! skeletal myofibril assembly GO:0014866 12 5 0,000 6,734E-03 0,06116001 ! smooth muscle tissue development GO:0048745 32 5 0,000 6,734E-03 0,06093349 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,734E-03 0,06070864 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,734E-03 0,06048545 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,734E-03 0,06026389 ! cardiac muscle fiber development GO:0048739 12 5 0,000 6,734E-03 0,06004395 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,734E-03 0,05982561 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 6,734E-03 0,05960885 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,734E-03 0,05939365 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 6,734E-03 0,05918001 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,734E-03 0,05896789 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,734E-03 0,05875729 ! glycine biosynthetic process GO:0006545 7 5 0,000 6,734E-03 0,05854819 ! microvillus organization GO:0032528 8 5 0,000 6,734E-03 0,05834057 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 6,734E-03 0,05813442 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 6,734E-03 0,05792972 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 6,734E-03 0,05772646 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 6,734E-03 0,05752462 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 6,734E-03 0,05732419 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 6,734E-03 0,05712515 ! polyol catabolic process GO:0046174 9 5 0,000 6,734E-03 0,05692748 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 6,734E-03 0,05673118 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 6,734E-03 0,05653623 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,734E-03 0,05634261 ! muscle cell migration GO:0014812 8 5 0,000 6,734E-03 0,05615031 ! mitochondrial fission GO:0000266 8 5 0,000 6,734E-03 0,05595933 ! sister chromatid cohesion GO:0007062 15 5 0,000 6,734E-03 0,05576963 ! response to tumor necrosis factor GO:0034612 10 5 0,000 6,734E-03 0,05558122 ! mRNA transcription GO:0009299 10 5 0,000 6,734E-03 0,05539408 ! nerve growth factor processing GO:0032455 9 5 0,000 6,734E-03 0,05520819 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 6,734E-03 0,05502355 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 6,734E-03 0,05484014 ! anaerobic glycolysis GO:0019642 6 5 0,000 6,734E-03 0,05465795 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,734E-03 0,05447696 ! monocyte activation GO:0042117 10 5 0,000 6,734E-03 0,05429717 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,734E-03 0,05411856 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,734E-03 0,05394112 ! response to food GO:0032094 6 5 0,000 6,734E-03 0,05376484 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,734E-03 0,05358971 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,734E-03 0,05341572 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 6,734E-03 0,05324285 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,734E-03 0,0530711 ! forebrain neuron development GO:0021884 13 5 0,000 6,734E-03 0,05290046 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,734E-03 0,0527309 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 6,734E-03 0,05256243 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 6,734E-03 0,05239504 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,734E-03 0,0522287 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,734E-03 0,05206342 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 6,734E-03 0,05189919 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,734E-03 0,05173598 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 6,734E-03 0,0515738 ! lipid glycosylation GO:0030259 7 5 0,000 6,734E-03 0,05141263 ! nucleobase transport GO:0015851 6 5 0,000 6,734E-03 0,05125247 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,734E-03 0,0510933 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 6,734E-03 0,05093511 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 6,734E-03 0,05077791 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 6,734E-03 0,05062167 ! basic amino acid transport GO:0015802 12 5 0,000 6,734E-03 0,05046639 ! cellular glucose homeostasis GO:0001678 6 5 0,000 6,734E-03 0,05031205 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 6,734E-03 0,05015866 ! actin nucleation GO:0045010 11 5 0,000 6,734E-03 0,05000621 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,734E-03 0,04985467 ! depurination GO:0045007 5 5 0,000 6,734E-03 0,04970405 ! depyrimidination GO:0045008 10 5 0,000 6,734E-03 0,04955434 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,734E-03 0,04940553 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,734E-03 0,04925761 ! G2/M transition checkpoint GO:0031576 8 5 0,000 6,734E-03 0,04911057 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,734E-03 0,04896441 ! zinc ion homeostasis GO:0055069 9 5 0,000 6,734E-03 0,04881912 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 6,734E-03 0,04867468 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 6,734E-03 0,0485311 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,734E-03 0,04838836 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,734E-03 0,04824646 ! activated T cell proliferation GO:0050798 16 5 0,000 6,734E-03 0,04810539 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,734E-03 0,04796514 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 6,734E-03 0,0478257 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,734E-03 0,04768708 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,734E-03 0,04754925 ! gamma-delta T cell activation GO:0046629 6 5 0,000 6,734E-03 0,04741222 ! response to arsenic GO:0046685 11 5 0,000 6,734E-03 0,04727598 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 6,734E-03 0,04714052 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,734E-03 0,04700583 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 6,734E-03 0,04687191 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 6,734E-03 0,04673876 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 6,734E-03 0,04660635 ! response to mercury ion GO:0046689 8 5 0,000 6,734E-03 0,04647469 ! response to cadmium ion GO:0046686 7 5 0,000 6,734E-03 0,04634378 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 6,734E-03 0,0462136 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 6,734E-03 0,04608415 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 6,734E-03 0,04595542 ! bile acid biosynthetic process GO:0006699 7 5 0,000 6,734E-03 0,04582741 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,734E-03 0,04570012 ! ganglioside catabolic process GO:0006689 12 5 0,000 6,734E-03 0,04557352 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,734E-03 0,04544763 ! decidualization GO:0046697 11 5 0,000 6,734E-03 0,04532243 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 6,734E-03 0,04519792 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 6,734E-03 0,04507409 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 6,734E-03 0,04495093 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 6,734E-03 0,04482845 ! embryonic cleavage GO:0040016 6 5 0,000 6,734E-03 0,04470664 ! peroxisome fission GO:0016559 5 5 0,000 6,734E-03 0,04458548 ! histone demethylation GO:0016577 13 5 0,000 6,734E-03 0,04446498 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 6,734E-03 0,04434513 ! mitotic recombination GO:0006312 9 5 0,000 6,734E-03 0,04422592 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 6,734E-03 0,04410735 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,734E-03 0,04398942 ! metaphase plate congression GO:0051310 7 5 0,000 6,734E-03 0,04387211 ! regulation of sterol transport GO:0032371 7 5 0,000 6,734E-03 0,04375543 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,734E-03 0,04363937 ! enteric nervous system development GO:0048484 8 5 0,000 6,734E-03 0,04352392 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 6,734E-03 0,04340908 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 6,734E-03 0,04329485 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 6,734E-03 0,04318121 ! muscle cell proliferation GO:0033002 12 5 0,000 6,734E-03 0,04306817 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 6,734E-03 0,04295572 ! B cell homeostasis GO:0001782 13 5 0,000 6,734E-03 0,04284386 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 6,734E-03 0,04273258 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,734E-03 0,04262187 ! metaphase GO:0051323 11 5 0,000 6,734E-03 0,04251174 ! melatonin biosynthetic process GO:0030187 7 5 0,000 6,734E-03 0,04240217 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 6,734E-03 0,04229317 ! cellular response to nutrient GO:0031670 8 5 0,000 6,734E-03 0,04218472 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,734E-03 0,04207683 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 6,734E-03 0,04196949 ! regulation of hair follicle development GO:0051797 10 5 0,000 6,734E-03 0,0418627 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 6,734E-03 0,04175645 ! response to redox state GO:0051775 6 5 0,000 6,734E-03 0,04165074 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 6,734E-03 0,04154556 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 6,734E-03 0,04144091 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,734E-03 0,04133679 ! brown fat cell differentiation GO:0050873 7 5 0,000 6,734E-03 0,04123319 ! regulation of telomerase activity GO:0051972 7 5 0,000 6,734E-03 0,0411301 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,734E-03 0,04102754 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 6,734E-03 0,04092548 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,734E-03 0,04082393 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 6,734E-03 0,04072288 ! striatum development GO:0021756 14 5 0,000 6,734E-03 0,04062233 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 6,734E-03 0,04052227 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,734E-03 0,04042271 ! glial cell migration GO:0008347 10 5 0,000 6,734E-03 0,04032363 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,734E-03 0,04022504 ! neural plate morphogenesis GO:0001839 7 5 0,000 6,734E-03 0,04012693 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 6,734E-03 0,0400293 ! T cell activation during immune response GO:0002286 9 5 0,000 6,734E-03 0,03993214 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,734E-03 0,03983545 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,734E-03 0,03973923 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 6,734E-03 0,03964347 ! neuroprotection GO:0043526 8 5 0,000 6,734E-03 0,03954818 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,734E-03 0,03945334 ! regulation of sensory perception GO:0051931 8 5 0,000 6,734E-03 0,03935895 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,734E-03 0,03926502 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,734E-03 0,03917153 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 6,734E-03 0,03907848 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 6,734E-03 0,03898588 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,734E-03 0,03889372 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 6,734E-03 0,03880199 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,734E-03 0,03871069 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 6,734E-03 0,03861982 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 6,734E-03 0,03852937 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,734E-03 0,03843935 ! spindle assembly GO:0051225 6 5 0,000 6,734E-03 0,03834975 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,734E-03 0,03826056 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,734E-03 0,03817179 ! protein palmitoylation GO:0018345 12 5 0,000 6,734E-03 0,03808343 ! drug metabolic process GO:0017144 7 5 0,000 6,734E-03 0,03799548 ! stem cell division GO:0017145 11 5 0,000 6,734E-03 0,03790793 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,734E-03 0,03782079 ! organ regeneration GO:0031100 7 5 0,000 6,734E-03 0,03773404 ! carnitine metabolic process GO:0009437 8 5 0,000 6,734E-03 0,03764769 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,734E-03 0,03756174 ! ossification GO:0001503 205 91 1,000 6,774E-03 0,03769604 ! bone development GO:0060348 206 92 1,000 6,918E-03 0,03841324 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 7,662E-03 0,04244725 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 7,815E-03 0,04319654 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 8,076E-03 0,04453591 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,076E-03 0,0444356 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 8,076E-03 0,04433575 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 8,076E-03 0,04423634 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 8,076E-03 0,04413738 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 8,076E-03 0,04403886 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 8,076E-03 0,04394077 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 8,076E-03 0,04384313 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 8,076E-03 0,04374591 ! response to oxygen radical GO:0000305 11 6 0,000 8,076E-03 0,04364913 ! positive regulation of axon extension GO:0045773 13 6 0,000 8,076E-03 0,04355278 ! myoblast cell fate commitment GO:0048625 18 6 0,000 8,076E-03 0,04345684 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 8,076E-03 0,04336134 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 8,076E-03 0,04326624 ! regulation of interferon-beta production GO:0032648 8 6 0,000 8,076E-03 0,04317157 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 8,076E-03 0,04307731 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 8,076E-03 0,04298346 ! forebrain regionalization GO:0021871 9 6 0,000 8,076E-03 0,04289002 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 8,076E-03 0,04279698 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 8,076E-03 0,04270435 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 8,076E-03 0,04261211 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 8,076E-03 0,04252027 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 8,076E-03 0,04242883 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 8,076E-03 0,04233778 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 8,076E-03 0,04224713 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 8,076E-03 0,04215685 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 8,076E-03 0,04206697 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 8,076E-03 0,04197746 ! malate metabolic process GO:0006108 13 6 0,000 8,076E-03 0,04188834 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 8,076E-03 0,04179959 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 8,076E-03 0,04171122 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 8,076E-03 0,04162322 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 8,076E-03 0,04153559 ! protein refolding GO:0042026 15 6 0,000 8,076E-03 0,04144834 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 8,076E-03 0,04136144 ! opsonization GO:0008228 8 6 0,000 8,076E-03 0,04127491 ! mating behavior GO:0007617 7 6 0,000 8,076E-03 0,04118874 ! erythrocyte maturation GO:0043249 8 6 0,000 8,076E-03 0,04110293 ! embryonic hemopoiesis GO:0035162 16 6 0,000 8,076E-03 0,04101748 ! protein amino acid dealkylation GO:0008214 15 6 0,000 8,076E-03 0,04093238 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 8,076E-03 0,04084763 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 8,076E-03 0,04076324 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 8,076E-03 0,04067919 ! response to interferon-gamma GO:0034341 16 6 0,000 8,076E-03 0,04059549 ! toxin metabolic process GO:0009404 11 6 0,000 8,076E-03 0,04051213 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 8,076E-03 0,04042911 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 8,076E-03 0,04034644 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 8,076E-03 0,0402641 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 8,076E-03 0,04018209 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 8,076E-03 0,04010042 ! cGMP-mediated signaling GO:0019934 14 6 0,000 8,076E-03 0,04001908 ! dorsal spinal cord development GO:0021516 10 6 0,000 8,076E-03 0,03993807 ! activation of MAPKKK activity GO:0000185 12 6 0,000 8,076E-03 0,03985739 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 8,076E-03 0,03977703 ! thymic T cell selection GO:0045061 16 6 0,000 8,076E-03 0,039697 ! sphingoid catabolic process GO:0046521 8 6 0,000 8,076E-03 0,03961728 ! protein lipoylation GO:0009249 10 6 0,000 8,076E-03 0,03953789 ! transepithelial chloride transport GO:0030321 12 6 0,000 8,076E-03 0,03945882 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 8,076E-03 0,03938006 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 8,076E-03 0,03930161 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 8,076E-03 0,03922347 ! glutamate catabolic process GO:0006538 12 6 0,000 8,076E-03 0,03914565 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 8,076E-03 0,03906813 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 8,076E-03 0,03899092 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 8,076E-03 0,03891402 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 8,076E-03 0,03883742 ! hyperosmotic response GO:0006972 10 6 0,000 8,076E-03 0,03876112 ! L-serine biosynthetic process GO:0006564 7 6 0,000 8,076E-03 0,03868511 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 8,076E-03 0,03860941 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 8,076E-03 0,038534 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 8,076E-03 0,03845888 ! urea metabolic process GO:0019627 7 6 0,000 8,076E-03 0,03838406 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 8,076E-03 0,03830953 ! neutrophil activation GO:0042119 7 6 0,000 8,076E-03 0,03823529 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 8,076E-03 0,03816133 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 8,076E-03 0,03808766 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 8,076E-03 0,03801427 ! paraxial mesoderm development GO:0048339 16 6 0,000 8,076E-03 0,03794117 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 8,076E-03 0,03786834 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 8,076E-03 0,0377958 ! neuron apoptosis GO:0051402 15 6 0,000 8,076E-03 0,03772353 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 8,076E-03 0,03765154 ! T cell mediated immunity GO:0002456 17 6 0,000 8,076E-03 0,03757982 ! negative regulation of platelet activation GO:0010544 9 6 0,000 8,076E-03 0,03750838 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 8,076E-03 0,03743721 ! carnitine transport GO:0015879 10 6 0,000 8,076E-03 0,0373663 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,076E-03 0,03729567 ! positive regulation of exocytosis GO:0045921 11 6 0,000 8,076E-03 0,0372253 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 8,076E-03 0,03715519 ! early endosome to late endosome transport GO:0045022 16 6 0,000 8,076E-03 0,03708535 ! 5S class rRNA transcription GO:0042791 13 6 0,000 8,076E-03 0,03701577 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 8,076E-03 0,03694646 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 8,076E-03 0,0368774 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 8,076E-03 0,0368086 ! sodium ion homeostasis GO:0055078 12 6 0,000 8,076E-03 0,03674005 ! establishment of spindle localization GO:0051293 16 6 0,000 8,076E-03 0,03667176 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 8,076E-03 0,03660372 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 8,076E-03 0,03653594 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 8,076E-03 0,03646841 ! response to UV-C GO:0010225 14 6 0,000 8,076E-03 0,03640112 ! astrocyte development GO:0014002 16 6 0,000 8,076E-03 0,03633408 ! protein targeting to lysosome GO:0006622 12 6 0,000 8,076E-03 0,03626729 ! purine base biosynthetic process GO:0009113 17 6 0,000 8,076E-03 0,03620075 ! interaction with symbiont GO:0051702 14 6 0,000 8,076E-03 0,03613445 ! regulation of dendrite development GO:0050773 16 6 0,000 8,076E-03 0,03606839 ! peptidyl-arginine modification GO:0018195 13 6 0,000 8,076E-03 0,03600257 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 8,076E-03 0,03593699 ! response to copper ion GO:0046688 10 6 0,000 8,076E-03 0,03587165 ! response to exogenous dsRNA GO:0043330 13 6 0,000 8,076E-03 0,03580655 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 8,076E-03 0,03574168 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,076E-03 0,03567705 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 8,076E-03 0,03561265 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 8,076E-03 0,03554848 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 8,076E-03 0,03548455 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,076E-03 0,03542084 ! nucleoside catabolic process GO:0009164 10 6 0,000 8,076E-03 0,03535736 ! hair follicle maturation GO:0048820 8 6 0,000 8,076E-03 0,03529411 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 8,076E-03 0,03523108 ! Schwann cell development GO:0014044 15 6 0,000 8,076E-03 0,03516828 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 8,076E-03 0,03510571 ! response to pheromone GO:0019236 6 6 0,000 8,076E-03 0,03504335 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 8,076E-03 0,03498122 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 8,076E-03 0,03491931 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 8,076E-03 0,03485761 ! base conversion or substitution editing GO:0016553 6 6 0,000 8,076E-03 0,03479613 ! subpallium development GO:0021544 15 6 0,000 8,076E-03 0,03473487 ! neural tube patterning GO:0021532 8 6 0,000 8,076E-03 0,03467383 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 8,076E-03 0,034613 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 8,076E-03 0,03455238 ! maintenance of organ identity GO:0048496 9 6 0,000 8,076E-03 0,03449197 ! G2 phase GO:0051319 16 6 0,000 8,076E-03 0,03443178 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 8,076E-03 0,03437179 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 8,076E-03 0,03431201 ! oxygen homeostasis GO:0032364 10 6 0,000 8,076E-03 0,03425244 ! establishment of planar polarity GO:0001736 7 6 0,000 8,076E-03 0,03419308 ! regulation of mast cell activation GO:0033003 13 6 0,000 8,076E-03 0,03413392 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 8,076E-03 0,03407497 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 8,076E-03 0,03401622 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 8,076E-03 0,03395767 ! receptor internalization GO:0031623 11 6 0,000 8,076E-03 0,03389933 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 8,076E-03 0,03384118 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 8,076E-03 0,03378323 ! neutrophil homeostasis GO:0001780 11 6 0,000 8,076E-03 0,03372548 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,076E-03 0,03366793 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 8,076E-03 0,03361058 ! protein deubiquitination GO:0016579 16 6 0,000 8,076E-03 0,03355341 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 8,076E-03 0,03349645 ! protein destabilization GO:0031648 9 6 0,000 8,076E-03 0,03343967 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 8,076E-03 0,03338309 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 8,076E-03 0,0333267 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 8,076E-03 0,0332705 ! regulation of viral transcription GO:0046782 11 6 0,000 8,076E-03 0,03321449 ! progesterone metabolic process GO:0042448 12 6 0,000 8,076E-03 0,03315867 ! negative regulation of axon extension GO:0030517 24 6 0,000 8,076E-03 0,03310303 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 8,076E-03 0,03304758 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 8,076E-03 0,03299232 ! triglyceride catabolic process GO:0019433 10 6 0,000 8,076E-03 0,03293724 ! determination of adult lifespan GO:0008340 17 6 0,000 8,076E-03 0,03288235 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 8,076E-03 0,03282763 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 8,076E-03 0,0327731 ! neural plate development GO:0001840 9 6 0,000 8,076E-03 0,03271875 ! catecholamine transport GO:0051937 9 6 0,000 8,076E-03 0,03266458 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 8,076E-03 0,03261059 ! sensory cilium assembly GO:0035058 10 6 0,000 8,076E-03 0,03255678 ! organ or tissue specific immune response GO:0002251 8 6 0,000 8,076E-03 0,03250314 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 8,076E-03 0,03244968 ! maternal placenta development GO:0001893 12 6 0,000 8,076E-03 0,0323964 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 8,076E-03 0,03234329 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 8,076E-03 0,03229036 ! negative regulation of B cell activation GO:0050869 14 6 0,000 8,076E-03 0,03223759 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 8,076E-03 0,032185 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 8,076E-03 0,03213259 ! positive regulation of coagulation GO:0050820 13 6 0,000 8,076E-03 0,03208034 ! cellular anion homeostasis GO:0030002 11 6 0,000 8,076E-03 0,03202826 GO:0055081|anion homeostasis, ! skeletal muscle tissue development GO:0007519 223 100 1,000 8,125E-03 0,03217215 GO:0060538|skeletal muscle organ development, ! tRNA transcription GO:0009304 17 7 0,000 9,416E-03 0,03722077 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 9,416E-03 0,03716064 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 9,416E-03 0,03710071 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,416E-03 0,03704096 ! regulation of helicase activity GO:0051095 16 7 0,000 9,416E-03 0,03698141 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 9,416E-03 0,03692205 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 9,416E-03 0,03686288 ! sleep GO:0030431 16 7 0,000 9,416E-03 0,0368039 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,416E-03 0,03674511 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 9,416E-03 0,03668651 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,416E-03 0,03662809 ! prostate gland development GO:0030850 14 7 0,000 9,416E-03 0,03656986 ! nucleotide-sugar transport GO:0015780 11 7 0,000 9,416E-03 0,03651181 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,416E-03 0,03645394 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,416E-03 0,03639626 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 9,416E-03 0,03633877 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,416E-03 0,03628145 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 9,416E-03 0,03622431 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 9,416E-03 0,03616736 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,416E-03 0,03611058 ! SMAD protein complex assembly GO:0007183 13 7 0,000 9,416E-03 0,03605398 ! glycolipid transport GO:0046836 11 7 0,000 9,416E-03 0,03599756 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,416E-03 0,03594131 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 9,416E-03 0,03588524 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 9,416E-03 0,03582934 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,416E-03 0,03577362 ! establishment of tissue polarity GO:0007164 8 7 0,000 9,416E-03 0,03571807 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 9,416E-03 0,0356627 ! mRNA stabilization GO:0048255 18 7 0,000 9,416E-03 0,03560749 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 9,416E-03 0,03555246 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 9,416E-03 0,03549759 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 9,416E-03 0,0354429 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 9,416E-03 0,03538837 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,416E-03 0,03533401 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,416E-03 0,03527981 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,416E-03 0,03522579 ! lipoprotein transport GO:0042953 14 7 0,000 9,416E-03 0,03517192 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 9,416E-03 0,03511823 ! rhythmic behavior GO:0007622 17 7 0,000 9,416E-03 0,03506469 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 9,416E-03 0,03501132 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 9,416E-03 0,03495811 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 9,416E-03 0,03490507 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 9,416E-03 0,03485218 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,416E-03 0,03479945 ! regulation of odontogenesis GO:0042481 14 7 0,000 9,416E-03 0,03474689 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,416E-03 0,03469448 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 9,416E-03 0,03464223 ! mechanosensory behavior GO:0007638 16 7 0,000 9,416E-03 0,03459013 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 9,416E-03 0,0345382 ! positive regulation of isotype switching GO:0045830 17 7 0,000 9,416E-03 0,03448642 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 9,416E-03 0,03443479 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 9,416E-03 0,03438332 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,416E-03 0,034332 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,416E-03 0,03428083 ! spinal cord patterning GO:0021511 14 7 0,000 9,416E-03 0,03422982 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 9,416E-03 0,03417896 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 9,416E-03 0,03412825 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,416E-03 0,03407769 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 9,416E-03 0,03402728 ! adrenal gland development GO:0030325 17 7 0,000 9,416E-03 0,03397701 ! cysteine metabolic process GO:0006534 13 7 0,000 9,416E-03 0,0339269 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 9,416E-03 0,03387694 ! ovulation GO:0030728 10 7 0,000 9,416E-03 0,03382712 ! adenohypophysis development GO:0021984 11 7 0,000 9,416E-03 0,03377744 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 9,416E-03 0,03372792 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 9,416E-03 0,03367853 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 9,416E-03 0,0336293 ! microtubule nucleation GO:0007020 21 7 0,000 9,416E-03 0,0335802 ! proline biosynthetic process GO:0006561 10 7 0,000 9,416E-03 0,03353125 ! tryptophan metabolic process GO:0006568 11 7 0,000 9,416E-03 0,03348244 ! thyroid hormone generation GO:0006590 13 7 0,000 9,416E-03 0,03343378 ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 9,416E-03 0,03338525 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,416E-03 0,03333687 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 9,416E-03 0,03328862 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 9,416E-03 0,03324052 ! galactose metabolic process GO:0006012 13 7 0,000 9,416E-03 0,03319255 ! vesicle fusion GO:0006906 20 7 0,000 9,416E-03 0,03314472 ! response to dietary excess GO:0002021 8 7 0,000 9,416E-03 0,03309703 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,416E-03 0,03304948 ! intracellular pH reduction GO:0051452 13 7 0,000 9,416E-03 0,03300206 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,416E-03 0,03295478 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 9,416E-03 0,03290764 ! organ growth GO:0035265 15 7 0,000 9,416E-03 0,03286063 ! nucleoside transport GO:0015858 11 7 0,000 9,416E-03 0,03281375 ! nucleoside salvage GO:0043174 11 7 0,000 9,416E-03 0,03276701 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 9,416E-03 0,0327204 ! male sex determination GO:0030238 15 7 0,000 9,416E-03 0,03267392 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 9,416E-03 0,03262757 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 9,416E-03 0,03258136 ! parturition GO:0007567 16 7 0,000 9,416E-03 0,03253527 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 9,416E-03 0,03248932 ! rRNA modification GO:0000154 14 7 0,000 9,416E-03 0,0324435 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 9,416E-03 0,0323978 ! spindle checkpoint GO:0031577 16 7 0,000 9,416E-03 0,03235223 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 9,416E-03 0,0323068 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 9,416E-03 0,03226149 ! monocyte differentiation GO:0030224 16 7 0,000 9,416E-03 0,0322163 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 9,416E-03 0,03217124 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,416E-03 0,03212631 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 9,416E-03 0,0320815 ! hyaluronan metabolic process GO:0030212 9 7 0,000 9,416E-03 0,03203682 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 9,416E-03 0,03199227 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,416E-03 0,03194783 ! fibrinolysis GO:0042730 11 7 0,000 9,416E-03 0,03190352 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 9,416E-03 0,03185933 ! skeletal muscle contraction GO:0003009 8 7 0,000 9,416E-03 0,03181527 ! eating behavior GO:0042755 8 7 0,000 9,416E-03 0,03177132 ! B cell lineage commitment GO:0002326 21 7 0,000 9,416E-03 0,0317275 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,416E-03 0,0316838 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 9,416E-03 0,03164022 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 9,416E-03 0,03159676 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,416E-03 0,03155341 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 9,416E-03 0,03151019 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,416E-03 0,03146708 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 9,416E-03 0,0314241 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 9,416E-03 0,03138123 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 9,416E-03 0,03133847 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 9,416E-03 0,03129584 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,416E-03 0,03125331 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 9,416E-03 0,03121091 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,416E-03 0,03116862 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,416E-03 0,03112644 ! histone ubiquitination GO:0016574 9 7 0,000 9,416E-03 0,03108438 ! regulation of meiosis GO:0040020 12 7 0,000 9,416E-03 0,03104243 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 9,416E-03 0,03100059 ! T cell lineage commitment GO:0002360 16 7 0,000 9,416E-03 0,03095887 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 9,416E-03 0,03091726 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,416E-03 0,03087576 ! membrane to membrane docking GO:0022614 14 7 0,000 9,416E-03 0,03083437 ! transcription termination GO:0006353 14 7 0,000 9,416E-03 0,03079309 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,416E-03 0,03075192 ! anaphase GO:0051322 18 7 0,000 9,416E-03 0,03071087 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 9,416E-03 0,03066992 ! axonal fasciculation GO:0007413 19 7 0,000 9,416E-03 0,03062908 ! negative regulation of nuclear division GO:0051784 15 7 0,000 9,416E-03 0,03058835 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 9,416E-03 0,03054773 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 9,416E-03 0,03050721 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 9,416E-03 0,03046681 ! diuresis GO:0030146 12 7 0,000 9,416E-03 0,03042651 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,416E-03 0,03038631 ! thiamin metabolic process GO:0006772 7 7 0,000 9,416E-03 0,03034623 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,416E-03 0,03030624 ! antibiotic transport GO:0042891 9 7 0,000 9,416E-03 0,03026637 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,416E-03 0,0302266 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 9,416E-03 0,03018693 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 9,416E-03 0,03014736 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 9,416E-03 0,0301079 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 9,416E-03 0,03006855 ! melanin biosynthetic process GO:0042438 10 7 0,000 9,416E-03 0,03002929 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 9,416E-03 0,02999014 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,416E-03 0,02995109 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,416E-03 0,02991214 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 9,416E-03 0,0298733 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 9,416E-03 0,02983455 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 9,416E-03 0,02979591 ! endosome to lysosome transport GO:0008333 12 7 0,000 9,416E-03 0,02975736 ! protein modification by small protein removal GO:0070646 19 7 0,000 9,416E-03 0,02971891 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 9,416E-03 0,02968057 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 9,416E-03 0,02964232 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 9,416E-03 0,02960417 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 9,416E-03 0,02956612 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,416E-03 0,02952816 ! embryonic heart tube development GO:0035050 14 7 0,000 9,416E-03 0,02949031 ! retina homeostasis GO:0001895 12 7 0,000 9,416E-03 0,02945255 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 9,416E-03 0,02941488 ! protein amino acid prenylation GO:0018346 19 7 0,000 9,416E-03 0,02937732 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 9,416E-03 0,02933985 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 9,416E-03 0,02930247 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01075364 0,03342384 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01075364 0,03338137 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01075364 0,03333901 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01075364 0,03329676 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01075364 0,03325461 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01075364 0,03321257 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01075364 0,03317063 ! male meiosis GO:0007140 9 8 0,000 0,01075364 0,0331288 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01075364 0,03308708 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01075364 0,03304546 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01075364 0,03300395 ! meiotic prophase I GO:0007128 14 8 0,000 0,01075364 0,03296254 ! response to zinc ion GO:0010043 12 8 0,000 0,01075364 0,03292123 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01075364 0,03288003 ! oligopeptide transport GO:0006857 16 8 0,000 0,01075364 0,03283893 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01075364 0,03279793 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01075364 0,03275703 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01075364 0,03271624 ! signal peptide processing GO:0006465 12 8 0,000 0,01075364 0,03267555 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01075364 0,03263496 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01075364 0,03259447 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01075364 0,03255408 ! succinate metabolic process GO:0006105 17 8 0,000 0,01075364 0,03251379 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01075364 0,0324736 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01075364 0,03243351 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01075364 0,03239352 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01075364 0,03235362 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01075364 0,03231383 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01075364 0,03227413 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01075364 0,03223453 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01075364 0,03219503 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01075364 0,03215562 ! reflex GO:0060004 17 8 0,000 0,01075364 0,03211631 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01075364 0,0320771 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01075364 0,03203798 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01075364 0,03199895 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01075364 0,03196003 ! pigment granule organization GO:0048753 17 8 0,000 0,01075364 0,03192119 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01075364 0,03188245 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01075364 0,03184381 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01075364 0,03180526 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01075364 0,0317668 ! histidine catabolic process GO:0006548 10 8 0,000 0,01075364 0,03172843 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01075364 0,03169016 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01075364 0,03165198 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01075364 0,03161389 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01075364 0,03157589 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01075364 0,03153799 ! melanin metabolic process GO:0006582 17 8 0,000 0,01075364 0,03150017 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01075364 0,03146244 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01075364 0,03142481 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01075364 0,03138727 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01075364 0,03134981 ! macrophage activation GO:0042116 13 8 0,000 0,01075364 0,03131245 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01075364 0,03127517 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01075364 0,03123798 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01075364 0,03120088 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01075364 0,03116387 ! purine salvage GO:0043101 12 8 0,000 0,01075364 0,03112694 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01075364 0,03109011 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01075364 0,03105336 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01075364 0,0310167 ! osteoblast development GO:0002076 17 8 0,000 0,01075364 0,03098012 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01075364 0,03094363 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01075364 0,03090723 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01075364 0,03087091 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01075364 0,03083467 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01075364 0,03079852 ! response to UV-B GO:0010224 17 8 0,000 0,01075364 0,03076246 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01075364 0,03072648 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01075364 0,03069059 ! intermediate filament organization GO:0045109 12 8 0,000 0,01075364 0,03065477 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01075364 0,03061905 ! cellular extravasation GO:0045123 13 8 0,000 0,01075364 0,0305834 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01075364 0,03054784 ! response to antibiotic GO:0046677 11 8 0,000 0,01075364 0,03051236 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01075364 0,03047696 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01075364 0,03044165 ! DNA topological change GO:0006265 12 8 0,000 0,01075364 0,03040641 ! response to tropane GO:0014073 15 8 0,000 0,01075364 0,03037126 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01075364 0,03033619 ! melanosome transport GO:0032402 13 8 0,000 0,01075364 0,0303012 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01075364 0,03026629 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01075364 0,03023146 ! mast cell activation GO:0045576 14 8 0,000 0,01075364 0,03019671 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01075364 0,03016205 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01075364 0,03012746 ! gas homeostasis GO:0033483 14 8 0,000 0,01075364 0,03009295 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01075364 0,03005851 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01075364 0,03002416 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01075364 0,02998989 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01075364 0,02995569 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01075364 0,02992157 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01075364 0,02988753 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01075364 0,02985357 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01075364 0,02981968 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01075364 0,02978587 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01075364 0,02975214 ! response to tumor cell GO:0002347 16 8 0,000 0,01075364 0,02971849 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01075364 0,02968491 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01075364 0,0296514 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01075364 0,02961797 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01075364 0,02958462 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01075364 0,02955134 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01075364 0,02951814 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01075364 0,02948501 ! hormone catabolic process GO:0042447 17 8 0,000 0,01075364 0,02945195 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01075364 0,02941897 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01075364 0,02938606 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01075364 0,02935323 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01075364 0,02932047 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01075364 0,02928778 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01075364 0,02925517 ! adult feeding behavior GO:0008343 10 8 0,000 0,01075364 0,02922263 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01075364 0,02919016 ! ATP catabolic process GO:0006200 11 8 0,000 0,01075364 0,02915776 ! blastocyst growth GO:0001832 19 8 0,000 0,01075364 0,02912543 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01075364 0,02909318 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01075364 0,029061 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01075364 0,02902889 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01075364 0,02899684 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01075364 0,02896487 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01075364 0,02893298 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01075364 0,02890115 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01075364 0,02886939 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01075364 0,0288377 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01075364 0,02880608 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01075364 0,02877453 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01075364 0,02874304 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01075364 0,02871163 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01075364 0,02868029 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01075364 0,02864901 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01075364 0,0286178 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01075364 0,02858666 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01075364 0,02855559 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01075364 0,02852458 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01075364 0,02849365 ! axon extension GO:0048675 16 9 0,000 0,01208986 0,03199948 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01208986 0,03196485 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01208986 0,03193029 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01208986 0,03189581 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01208986 0,0318614 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01208986 0,03182707 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01208986 0,03179281 ! reproductive behavior GO:0019098 22 9 0,000 0,01208986 0,03175862 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01208986 0,03172451 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01208986 0,03169047 ! UTP metabolic process GO:0046051 10 9 0,000 0,01208986 0,03165651 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01208986 0,03162261 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01208986 0,03158879 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01208986 0,03155504 ! artery development GO:0060840 25 9 0,000 0,01208986 0,03152137 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01208986 0,03148776 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01208986 0,03145423 ! equilibrioception GO:0050957 20 9 0,000 0,01208986 0,03142077 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01208986 0,03138738 ! chemosensory behavior GO:0007635 21 9 0,000 0,01208986 0,03135406 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01208986 0,03132081 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01208986 0,03128763 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01208986 0,03125452 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01208986 0,03122148 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01208986 0,03118851 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01208986 0,03115561 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01208986 0,03112278 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01208986 0,03109002 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01208986 0,03105733 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01208986 0,03102471 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01208986 0,03099215 ! protein targeting to ER GO:0045047 25 9 0,000 0,01208986 0,03095967 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01208986 0,03092725 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01208986 0,0308949 ! T cell selection GO:0045058 27 9 0,000 0,01208986 0,03086261 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01208986 0,0308304 ! glycine catabolic process GO:0006546 15 9 0,000 0,01208986 0,03079825 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01208986 0,03076617 ! endosome organization GO:0007032 20 9 0,000 0,01208986 0,03073415 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01208986 0,0307022 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01208986 0,03067032 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01208986 0,03063851 ! mannose metabolic process GO:0006013 13 9 0,000 0,01208986 0,03060676 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01208986 0,03057507 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01208986 0,03054345 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01208986 0,0305119 ! receptor clustering GO:0043113 20 9 0,000 0,01208986 0,03048041 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01208986 0,03044899 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01208986 0,03041763 ! retinol metabolic process GO:0042572 20 9 0,000 0,01208986 0,03038634 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01208986 0,03035511 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01208986 0,03032394 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01208986 0,03029284 ! macrophage differentiation GO:0030225 15 9 0,000 0,01208986 0,0302618 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01208986 0,03023083 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01208986 0,03019992 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01208986 0,03016907 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01208986 0,03013829 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01208986 0,03010756 ! response to amine stimulus GO:0014075 13 9 0,000 0,01208986 0,03007691 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01208986 0,03004631 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01208986 0,03001577 ! erythrocyte development GO:0048821 17 9 0,000 0,01208986 0,0299853 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01208986 0,02995489 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01208986 0,02992454 ! renal water homeostasis GO:0003091 15 9 0,000 0,01208986 0,02989425 ! postreplication repair GO:0006301 25 9 0,000 0,01208986 0,02986403 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01208986 0,02983386 ! icosanoid secretion GO:0032309 15 9 0,000 0,01208986 0,02980375 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01208986 0,02977371 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01208986 0,02974373 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01208986 0,0297138 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01208986 0,02968394 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01208986 0,02965414 ! sterol catabolic process GO:0016127 14 9 0,000 0,01208986 0,02962439 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01208986 0,02959471 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01208986 0,02956509 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01208986 0,02953552 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01208986 0,02950601 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01208986 0,02947657 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01208986 0,02944718 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01208986 0,02941785 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01208986 0,02938858 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01208986 0,02935936 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01208986 0,02933021 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01208986 0,02930111 ! purine base metabolic process GO:0006144 25 9 0,000 0,01208986 0,02927207 ! pigment granule transport GO:0051904 17 9 0,000 0,01208986 0,02924309 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01208986 0,02921417 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01208986 0,0291853 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01208986 0,02915649 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01208986 0,02912773 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01208986 0,02909904 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01208986 0,02907039 ! mitochondrion localization GO:0051646 18 9 0,000 0,01208986 0,02904181 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01342431 0,0322157 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01342431 0,03218409 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01342431 0,03215253 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01342431 0,03212104 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01342431 0,03208961 ! associative learning GO:0008306 21 10 0,000 0,01342431 0,03205824 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01342431 0,03202694 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01342431 0,03199569 ! phosphate transport GO:0006817 24 10 0,000 0,01342431 0,03196451 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01342431 0,03193338 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01342431 0,03190232 ! CTP metabolic process GO:0046036 11 10 0,000 0,01342431 0,03187131 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01342431 0,03184037 ! GTP metabolic process GO:0046039 11 10 0,000 0,01342431 0,03180949 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01342431 0,03177867 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01342431 0,0317479 ! social behavior GO:0035176 29 10 0,000 0,01342431 0,0317172 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01342431 0,03168655 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01342431 0,03165597 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01342431 0,03162544 ! androgen metabolic process GO:0008209 17 10 0,000 0,01342431 0,03159497 ! phospholipid efflux GO:0033700 19 10 0,000 0,01342431 0,03156456 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01342431 0,03153421 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01342431 0,03150392 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01342431 0,03147369 ! lung alveolus development GO:0048286 26 10 0,000 0,01342431 0,03144351 ! pathogenesis GO:0009405 17 10 0,000 0,01342431 0,03141339 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01342431 0,03138333 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01342431 0,03135333 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01342431 0,03132338 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01342431 0,03129349 ! endoderm development GO:0007492 18 10 0,000 0,01342431 0,03126366 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01342431 0,03123389 ! arginine catabolic process GO:0006527 17 10 0,000 0,01342431 0,03120417 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01342431 0,03117451 ! proline metabolic process GO:0006560 13 10 0,000 0,01342431 0,0311449 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01342431 0,03111535 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01342431 0,03108586 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01342431 0,03105642 ! V(D)J recombination GO:0033151 34 10 0,000 0,01342431 0,03102704 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01342431 0,03099772 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01342431 0,03096844 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01342431 0,03093923 ! B cell proliferation GO:0042100 19 10 0,000 0,01342431 0,03091007 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01342431 0,03088096 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01342431 0,03085191 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01342431 0,03082292 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01342431 0,03079397 ! ruffle organization GO:0031529 17 10 0,000 0,01342431 0,03076509 ! epithelial cell development GO:0002064 21 10 0,000 0,01342431 0,03073625 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01342431 0,03070747 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01342431 0,03067875 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01342431 0,03065008 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01342431 0,03062146 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01342431 0,03059289 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01342431 0,03056438 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01342431 0,03053592 ! motor axon guidance GO:0008045 22 10 0,000 0,01342431 0,03050752 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01342431 0,03047917 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01342431 0,03045087 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01342431 0,03042262 ! brain morphogenesis GO:0048854 23 10 0,000 0,01342431 0,03039442 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01342431 0,03036628 ! segment specification GO:0007379 15 10 0,000 0,01342431 0,03033819 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01342431 0,03031015 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01342431 0,03028216 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01342431 0,03025423 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01342431 0,03022634 ! response to dsRNA GO:0043331 23 10 0,000 0,01342431 0,03019851 ! DNA ligation GO:0006266 18 10 0,000 0,01342431 0,03017073 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01342431 0,030143 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01342431 0,03011532 ! melanosome localization GO:0032400 16 10 0,000 0,01342431 0,03008769 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01342431 0,03006011 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01342431 0,03003258 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01342431 0,03000511 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01342431 0,02997768 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01342431 0,0299503 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01342431 0,02992298 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01342431 0,0298957 ! protein sumoylation GO:0016925 17 10 0,000 0,01342431 0,02986847 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01342431 0,02984129 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01342431 0,02981417 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01342431 0,02978709 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01342431 0,02976006 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01342431 0,02973308 ! salivary gland development GO:0007431 28 10 0,000 0,01342431 0,02970614 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01342431 0,02967926 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01342431 0,02965243 ! midbrain development GO:0030901 14 10 0,000 0,01342431 0,02962564 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01342431 0,0295989 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01342431 0,02957221 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01342431 0,02954557 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01342431 0,02951898 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01342431 0,02949243 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01342431 0,02946593 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01342431 0,02943948 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01342431 0,02941308 ! detection of calcium ion GO:0005513 24 10 0,000 0,01342431 0,02938672 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01342431 0,02936041 ! blastocyst formation GO:0001825 18 10 0,000 0,01342431 0,02933415 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01342431 0,02930794 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01342431 0,02928177 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01342431 0,02925565 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01342431 0,02922957 ! response to nicotine GO:0035094 20 10 0,000 0,01342431 0,02920355 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01342431 0,02917756 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01342431 0,02915163 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01475699 0,03201717 ! respiratory burst GO:0045730 17 11 0,000 0,01475699 0,03198876 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01475699 0,0319604 ! neuron fate specification GO:0048665 18 11 0,000 0,01475699 0,03193209 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01475699 0,03190383 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01475699 0,03187563 ! thyroid gland development GO:0030878 26 11 0,000 0,01475699 0,03184747 ! synapsis GO:0007129 14 11 0,000 0,01475699 0,03181936 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01475699 0,0317913 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01475699 0,03176329 ! response to pain GO:0048265 27 11 0,000 0,01475699 0,03173533 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01475699 0,03170742 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01475699 0,03167955 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01475699 0,03165174 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01475699 0,03162398 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01475699 0,03159626 ! bone resorption GO:0045453 16 11 0,000 0,01475699 0,03156859 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01475699 0,03154097 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01475699 0,0315134 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01475699 0,03148588 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01475699 0,03145841 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01475699 0,03143098 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01475699 0,0314036 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01475699 0,03137627 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01475699 0,03134898 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01475699 0,03132175 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01475699 0,03129456 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01475699 0,03126742 ! UV protection GO:0009650 20 11 0,000 0,01475699 0,03124032 ! adult heart development GO:0007512 16 11 0,000 0,01475699 0,03121327 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01475699 0,03118627 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01475699 0,03115932 ! macroautophagy GO:0016236 19 11 0,000 0,01475699 0,03113241 ! temperature homeostasis GO:0001659 18 11 0,000 0,01475699 0,03110555 ! behavioral fear response GO:0001662 27 11 0,000 0,01475699 0,03107873 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01475699 0,03105197 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01475699 0,03102524 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01475699 0,03099857 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01475699 0,03097194 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01475699 0,03094535 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01475699 0,03091881 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01475699 0,03089232 ! regulation of organ growth GO:0046620 14 11 0,000 0,01475699 0,03086587 ! pigment granule localization GO:0051875 20 11 0,000 0,01475699 0,03083946 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01475699 0,0308131 ! vasoconstriction GO:0042310 20 11 0,000 0,01475699 0,03078679 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01475699 0,03076052 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01475699 0,0307343 ! embryonic axis specification GO:0000578 19 11 0,000 0,01475699 0,03070812 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01475699 0,03068199 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01475699 0,03065589 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01475699 0,03062985 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01475699 0,03060385 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01475699 0,03057789 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01475699 0,03055198 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01475699 0,03052611 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01475699 0,03050028 ! prophase GO:0051324 17 11 0,000 0,01475699 0,0304745 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01475699 0,03044876 ! nucleosome positioning GO:0016584 15 11 0,000 0,01475699 0,03042307 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01475699 0,03039741 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01475699 0,0303718 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01475699 0,03034624 ! apical protein localization GO:0045176 18 11 0,000 0,01475699 0,03032072 ! acid secretion GO:0046717 20 11 0,000 0,01475699 0,03029524 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01475699 0,0302698 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01475699 0,03024441 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01475699 0,03021905 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01475699 0,03019375 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01475699 0,03016848 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01475699 0,03014325 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01475699 0,03011807 ! cholesterol efflux GO:0033344 21 11 0,000 0,01475699 0,03009293 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01475699 0,03006783 ! oocyte development GO:0048599 20 11 0,000 0,01475699 0,03004278 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01475699 0,03001776 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01475699 0,02999279 ! embryonic gut development GO:0048566 19 11 0,000 0,01475699 0,02996786 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01475699 0,02994297 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01475699 0,02991812 ! activation of innate immune response GO:0002218 16 11 0,000 0,01475699 0,02989331 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01475699 0,02986854 ! lysogeny GO:0030069 22 11 0,000 0,01475699 0,02984382 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01475699 0,02981913 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01475699 0,02979449 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01475699 0,02976989 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01475699 0,02974532 ! nucleus localization GO:0051647 22 11 0,000 0,01475699 0,0297208 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01608791 0,03237461 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01608791 0,03234796 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01608791 0,03232136 ! virus-host interaction GO:0019048 30 12 0,000 0,01608791 0,0322948 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01608791 0,03226829 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01608791 0,03224182 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01608791 0,03221539 ! protein complex disassembly GO:0043241 28 12 0,000 0,01608791 0,03218901 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01608791 0,03216266 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01608791 0,03213637 ! hippocampus development GO:0021766 29 12 0,000 0,01608791 0,03211011 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01608791 0,0320839 ! T cell proliferation GO:0042098 32 12 0,000 0,01608791 0,03205773 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01608791 0,0320316 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01608791 0,03200552 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01608791 0,03197948 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01608791 0,03195348 ! drug transport GO:0015893 16 12 0,000 0,01608791 0,03192752 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01608791 0,0319016 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01608791 0,03187573 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01608791 0,0318499 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01608791 0,03182411 ! focal adhesion formation GO:0048041 37 12 0,000 0,01608791 0,03179836 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01608791 0,03177266 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01608791 0,03174699 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01608791 0,03172137 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01608791 0,03169579 ! lipid digestion GO:0044241 21 12 0,000 0,01608791 0,03167025 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01608791 0,03164475 ! entry into host cell GO:0030260 34 12 0,000 0,01608791 0,03161929 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01608791 0,03159387 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01608791 0,03156849 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01608791 0,03154316 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01608791 0,03151786 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01608791 0,03149261 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01608791 0,03146739 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01608791 0,03144222 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01608791 0,03141709 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01608791 0,03139199 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01608791 0,03136694 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01608791 0,03134193 ! cranial nerve development GO:0021545 23 12 0,000 0,01608791 0,03131695 ! fucose catabolic process GO:0019317 25 12 0,000 0,01608791 0,03129202 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01608791 0,03126712 ! histone acetylation GO:0016573 27 12 0,000 0,01608791 0,03124227 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01608791 0,03121745 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01608791 0,03119268 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01608791 0,03116794 ! zymogen activation GO:0031638 18 12 0,000 0,01608791 0,03114325 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01608791 0,03111859 ! T cell homeostasis GO:0043029 28 12 0,000 0,01608791 0,03109397 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01608791 0,03106939 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01608791 0,03104485 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01608791 0,03102034 ! oocyte differentiation GO:0009994 21 12 0,000 0,01608791 0,03099588 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01608791 0,03097145 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01608791 0,03094707 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01608791 0,03092272 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01608791 0,03089841 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01608791 0,03087414 ! defense response to fungus GO:0050832 15 12 0,000 0,01608791 0,0308499 ! embryonic placenta development GO:0001892 21 12 0,000 0,01608791 0,03082571 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01608791 0,03080155 ! response to cold GO:0009409 17 12 0,000 0,01608791 0,03077743 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01608791 0,03075335 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01608791 0,0307293 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01741708 0,03324212 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01741708 0,03321617 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01741708 0,03319026 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01741708 0,03316439 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01741708 0,03313857 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01741708 0,03311278 ! peroxisomal transport GO:0043574 28 13 0,000 0,01741708 0,03308703 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01741708 0,03306132 ! cartilage condensation GO:0001502 22 13 0,000 0,01741708 0,03303565 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01741708 0,03301002 ! organelle fusion GO:0048284 36 13 0,000 0,01741708 0,03298443 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01741708 0,03295888 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01741708 0,03293337 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01741708 0,0329079 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01741708 0,03288247 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01741708 0,03285708 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01741708 0,03283173 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01741708 0,03280641 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01741708 0,03278114 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01741708 0,0327559 ! methionine metabolic process GO:0006555 31 13 0,000 0,01741708 0,03273071 ! plasma membrane organization GO:0007009 27 13 0,000 0,01741708 0,03270555 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01741708 0,03268043 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01741708 0,03265535 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01741708 0,03263031 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01741708 0,0326053 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01741708 0,03258034 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01741708 0,03255541 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01741708 0,03253052 ! exocrine system development GO:0035272 34 13 0,000 0,01741708 0,03250567 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01741708 0,03248085 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01741708 0,03245608 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01741708 0,03243134 ! L-glutamate transport GO:0015813 30 13 0,000 0,01741708 0,03240664 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01741708 0,03238198 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01741708 0,03235735 ! protein homotetramerization GO:0051289 24 13 0,000 0,01741708 0,03233276 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01741708 0,03230821 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01741708 0,0322837 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01741708 0,03225923 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01741708 0,03223479 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01741708 0,03221038 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01741708 0,03218602 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01741708 0,03216169 ! histone methylation GO:0016571 29 13 0,000 0,01741708 0,0321374 ! chromatin silencing GO:0006342 29 13 0,000 0,01741708 0,03211315 ! gland morphogenesis GO:0022612 31 13 0,000 0,01741708 0,03208893 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01741708 0,03206475 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01741708 0,0320406 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01741708 0,03201649 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01741708 0,03199242 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01741708 0,03196838 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01741708 0,03194438 ! spleen development GO:0048536 24 13 0,000 0,01741708 0,03192042 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01741708 0,03189649 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01741708 0,0318726 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01741708 0,03184874 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01741708 0,03182492 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01741708 0,03180113 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01741708 0,03177738 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01741708 0,03175367 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01741708 0,03172999 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01741708 0,03170635 ! insulin secretion GO:0030073 24 13 0,000 0,01741708 0,03168274 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01741708 0,03165917 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01741708 0,03163563 ! acrosome reaction GO:0007340 19 13 0,000 0,01741708 0,03161212 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01741708 0,03158865 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01741708 0,03156522 ! rRNA transcription GO:0009303 28 14 0,000 0,01874448 0,03394571 ! regulation of S phase GO:0033261 26 14 0,000 0,01874448 0,03392057 ! water transport GO:0006833 21 14 0,000 0,01874448 0,03389546 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 29 14 0,000 0,01874448 0,03387039 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01874448 0,03384536 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01874448 0,03382036 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01874448 0,0337954 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01874448 0,03377048 ! lipid localization GO:0010876 32 14 0,000 0,01874448 0,03374559 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01874448 0,03372074 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01874448 0,03369593 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01874448 0,03367115 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01874448 0,03364641 ! arginine metabolic process GO:0006525 21 14 0,000 0,01874448 0,03362171 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01874448 0,03359704 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01874448 0,03357241 ! regulation of heart rate GO:0002027 25 14 0,000 0,01874448 0,03354781 ! fear response GO:0042596 34 14 0,000 0,01874448 0,03352325 ! organic alcohol transport GO:0015850 29 14 0,000 0,01874448 0,03349873 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01874448 0,03347424 ! embryo implantation GO:0007566 30 14 0,000 0,01874448 0,03344979 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01874448 0,03342538 ! bone mineralization GO:0030282 18 14 0,000 0,01874448 0,033401 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01874448 0,03337665 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01874448 0,03335234 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01874448 0,03332807 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01874448 0,03330383 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01874448 0,03327963 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01874448 0,03325546 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01874448 0,03323132 ! ribosome assembly GO:0042255 18 14 0,000 0,01874448 0,03320723 ! cerebellum development GO:0021549 23 14 0,000 0,01874448 0,03318316 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01874448 0,03315913 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01874448 0,03313514 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01874448 0,03311118 ! response to gamma radiation GO:0010332 30 14 0,000 0,01874448 0,03308726 ! NADP metabolic process GO:0006739 24 14 0,000 0,01874448 0,03306337 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01874448 0,03303951 ! oxygen transport GO:0015671 22 14 0,000 0,01874448 0,03301569 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01874448 0,03299191 ! male genitalia development GO:0030539 26 14 0,000 0,01874448 0,03296815 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01874448 0,03294444 ! regulation of axon extension GO:0030516 43 14 0,000 0,01874448 0,03292075 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01874448 0,0328971 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01874448 0,03287349 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01874448 0,0328499 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02007013 0,0351479 ! lactation GO:0007595 30 15 0,000 0,02007013 0,03512272 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02007013 0,03509758 ! reproductive cellular process GO:0048610 22 15 0,000 0,02007013 0,03507248 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02007013 0,03504741 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02007013 0,03502237 ! superoxide anion generation GO:0042554 22 15 0,000 0,02007013 0,03499738 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02007013 0,03497241 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02007013 0,03494749 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02007013 0,03492259 ! copper ion transport GO:0006825 22 15 0,000 0,02007013 0,03489774 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02007013 0,03487292 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02007013 0,03484813 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02007013 0,03482338 ! sulfate transport GO:0008272 27 15 0,000 0,02007013 0,03479867 ! response to cAMP GO:0051591 25 15 0,000 0,02007013 0,03477399 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02007013 0,03474934 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02007013 0,03472473 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02007013 0,03470016 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02007013 0,03467562 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02007013 0,03465111 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02007013 0,03462664 ! vesicle coating GO:0006901 38 15 0,000 0,02007013 0,0346022 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02007013 0,0345778 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02007013 0,03455343 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02007013 0,0345291 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02007013 0,0345048 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02007013 0,03448054 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02007013 0,03445631 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02007013 0,03443211 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02007013 0,03440795 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02007013 0,03438382 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02007013 0,03435972 ! histone deacetylation GO:0016575 24 15 0,000 0,02007013 0,03433566 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02007013 0,03431163 ! cofactor transport GO:0051181 30 15 0,000 0,02007013 0,03428764 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02007013 0,03426368 ! muscle maintenance GO:0046716 26 15 0,000 0,02007013 0,03423975 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02007013 0,03421586 ! intestinal absorption GO:0050892 31 15 0,000 0,02007013 0,034192 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02007013 0,03416817 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02007013 0,03414438 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02007013 0,03412061 ! cell killing GO:0001906 32 15 0,000 0,02007013 0,03409689 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02007013 0,03407319 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02007013 0,03404953 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02007013 0,0340259 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02007013 0,0340023 ! actin filament polymerization GO:0030041 27 15 0,000 0,02007013 0,03397874 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02007013 0,03395521 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02139402 0,03616996 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02139402 0,03614495 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02139402 0,03611997 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02139402 0,03609503 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02139402 0,03607011 ! bone remodeling GO:0046849 28 16 0,000 0,02139402 0,03604524 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02139402 0,0360204 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02139402 0,03599559 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02139402 0,03597082 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02139402 0,03594608 ! startle response GO:0001964 28 16 0,000 0,02139402 0,03592137 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02139402 0,0358967 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02139402 0,03587206 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02139402 0,03584746 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02139402 0,03582289 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02139402 0,03579835 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02139402 0,03577385 ! pituitary gland development GO:0021983 30 16 0,000 0,02139402 0,03574938 ! response to osmotic stress GO:0006970 27 16 0,000 0,02139402 0,03572495 ! lysosomal transport GO:0007041 31 16 0,000 0,02139402 0,03570054 ! fructose metabolic process GO:0006000 25 16 0,000 0,02139402 0,03567617 ! L-amino acid transport GO:0015807 33 16 0,000 0,02139402 0,03565184 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02139402 0,03562754 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02139402 0,03560327 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02139402 0,03557903 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02139402 0,03555483 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02139402 0,03553066 ! axon cargo transport GO:0008088 46 16 0,000 0,02139402 0,03550652 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02139402 0,03548241 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02139402 0,03545834 ! DNA replication initiation GO:0006270 28 16 0,000 0,02139402 0,0354343 ! neuron recognition GO:0008038 40 16 0,000 0,02139402 0,0354103 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02139402 0,03538632 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02139402 0,03536238 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02139402 0,03533847 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02139402 0,03531459 ! biomineral formation GO:0031214 22 16 0,000 0,02139402 0,03529075 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02139402 0,03526693 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02139402 0,03524315 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02139402 0,0352194 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02139402 0,03519569 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02139402 0,035172 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02139402 0,03514835 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02139402 0,03512473 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02139402 0,03510114 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02139402 0,03507758 ! peptide hormone processing GO:0016486 27 16 0,000 0,02139402 0,03505406 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02271616 0,03719544 ! metencephalon development GO:0022037 32 17 0,000 0,02271616 0,03717052 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02271616 0,03714564 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02271616 0,0371208 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02271616 0,03709598 ! signal complex assembly GO:0007172 47 17 0,000 0,02271616 0,0370712 ! filopodium assembly GO:0046847 42 17 0,000 0,02271616 0,03704646 ! endothelial cell migration GO:0043542 31 17 0,000 0,02271616 0,03702174 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02271616 0,03699706 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02271616 0,03697241 ! glial cell development GO:0021782 28 17 0,000 0,02271616 0,0369478 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02271616 0,03692321 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02271616 0,03689866 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02271616 0,03687415 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02271616 0,03684966 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02271616 0,03682521 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02271616 0,03680079 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02271616 0,0367764 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02271616 0,03675205 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02271616 0,03672772 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02271616 0,03670343 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02271616 0,03667917 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02271616 0,03665495 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02271616 0,03663075 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02271616 0,03660659 ! membrane budding GO:0006900 42 17 0,000 0,02271616 0,03658246 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02271616 0,03655836 ! regulation of protein binding GO:0043393 33 17 0,000 0,02271616 0,03653429 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02271616 0,03651026 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02271616 0,03648625 ! genitalia development GO:0048806 32 17 0,000 0,02271616 0,03646228 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02271616 0,03643834 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02271616 0,03641443 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02271616 0,03639055 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02271616 0,0363667 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02271616 0,03634289 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02271616 0,0363191 ! steroid catabolic process GO:0006706 34 17 0,000 0,02271616 0,03629535 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02271616 0,03627163 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02271616 0,03624794 ! gas transport GO:0015669 26 17 0,000 0,02271616 0,03622428 ! organic cation transport GO:0015695 32 17 0,000 0,02271616 0,03620065 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02271616 0,03617705 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02271616 0,03615348 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02271616 0,03612994 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02403656 0,03820515 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02403656 0,03818031 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02403656 0,0381555 ! limbic system development GO:0021761 40 18 0,000 0,02403656 0,03813072 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02403656 0,03810598 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02403656 0,03808127 ! adult walking behavior GO:0007628 36 18 0,000 0,02403656 0,03805659 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02403656 0,03803194 ! heart looping GO:0001947 34 18 0,000 0,02403656 0,03800732 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02403656 0,03798274 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02403656 0,03795819 ! centrosome cycle GO:0007098 26 18 0,000 0,02403656 0,03793366 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02403656 0,03790918 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02403656 0,03788472 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02403656 0,03786029 ! glycine metabolic process GO:0006544 30 18 0,000 0,02403656 0,0378359 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02403656 0,03781153 ! response to retinoic acid GO:0032526 31 18 0,000 0,02403656 0,0377872 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02403656 0,0377629 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02403656 0,03773863 ! DNA integration GO:0015074 32 18 0,000 0,02403656 0,03771439 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02403656 0,03769019 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02403656 0,03766601 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02403656 0,03764187 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02403656 0,03761775 ! neural crest cell migration GO:0001755 41 18 0,000 0,02403656 0,03759367 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02403656 0,03756962 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02403656 0,0375456 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02403656 0,03752161 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02403656 0,03749765 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02403656 0,03747372 ! detection of bacterium GO:0016045 22 18 0,000 0,02403656 0,03744982 ! nerve development GO:0021675 34 18 0,000 0,02403656 0,03742595 ! defense response to virus GO:0051607 43 18 0,000 0,02403656 0,03740211 ! microspike assembly GO:0030035 46 18 0,000 0,02403656 0,0373783 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02403656 0,03735452 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02403656 0,03733078 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02535521 0,03935373 ! positive regulation of translation GO:0045727 31 19 0,000 0,02535521 0,03932874 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02535521 0,03930379 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02535521 0,03927886 ! neuron maturation GO:0042551 46 19 0,000 0,02535521 0,03925397 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02535521 0,03922911 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02535521 0,03920428 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02535521 0,03917949 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02535521 0,03915472 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02535521 0,03912999 ! inositol metabolic process GO:0006020 33 19 0,000 0,02535521 0,03910528 ! memory GO:0007613 34 19 0,000 0,02535521 0,03908061 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02535521 0,03905597 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02535521 0,03903136 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02535521 0,03900678 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02535521 0,03898223 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02535521 0,03895771 ! cerebral cortex development GO:0021987 40 19 0,000 0,02535521 0,03893323 ! pigmentation during development GO:0048066 42 19 0,000 0,02535521 0,03890877 ! response to vitamin A GO:0033189 32 19 0,000 0,02535521 0,03888435 ! heme metabolic process GO:0042168 40 19 0,000 0,02535521 0,03885995 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02535521 0,03883559 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02535521 0,03881126 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02535521 0,03878695 ! response to fungus GO:0009620 26 19 0,000 0,02535521 0,03876268 ! peptide cross-linking GO:0018149 39 19 0,000 0,02535521 0,03873844 ! protein export from nucleus GO:0006611 40 19 0,000 0,02535521 0,03871423 ! heart process GO:0003015 32 19 0,000 0,02535521 0,03869005 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02535521 0,0386659 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02535521 0,03864178 ! visual learning GO:0008542 38 19 0,000 0,02535521 0,03861768 ! cellular pigmentation GO:0033059 37 19 0,000 0,02535521 0,03859362 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02535521 0,03856959 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02535521 0,03854559 ! vitamin transport GO:0051180 31 19 0,000 0,02535521 0,03852162 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02535521 0,03849768 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02535521 0,03847377 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02535521 0,03844989 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02535521 0,03842603 ! cilium assembly GO:0042384 38 19 0,000 0,02535521 0,03840221 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02535521 0,03837842 ! protein secretion GO:0009306 45 20 0,000 0,02667211 0,04034672 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02667211 0,04032176 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02667211 0,04029682 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02667211 0,04027192 ! skin development GO:0043588 42 20 0,000 0,02667211 0,04024704 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02667211 0,0402222 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02667211 0,04019738 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02667211 0,0401726 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02667211 0,04014785 ! response to vitamin GO:0033273 36 20 0,000 0,02667211 0,04012313 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02667211 0,04009844 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02667211 0,04007378 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02667211 0,04004914 ! response to alkaloid GO:0043279 38 20 0,000 0,02667211 0,04002454 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02667211 0,03999997 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02667211 0,03997543 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02667211 0,03995092 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02667211 0,03992645 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02667211 0,039902 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,02667211 0,03987758 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,02667211 0,03985319 ! body fluid secretion GO:0007589 33 20 0,000 0,02667211 0,03982883 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02667211 0,0398045 ! peptide secretion GO:0002790 38 20 0,000 0,02667211 0,03978019 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02667211 0,03975592 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02667211 0,03973168 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02667211 0,03970747 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02667211 0,03968329 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02667211 0,03965913 ! cell-cell junction organization GO:0045216 43 20 0,000 0,02667211 0,03963501 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02667211 0,03961092 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02667211 0,03958685 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02667211 0,03956282 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02667211 0,03953881 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02667211 0,03951483 ! regulation of glucose import GO:0046324 30 20 0,000 0,02667211 0,03949088 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02667211 0,03946696 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02667211 0,03944307 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02667211 0,03941921 ! negative regulation of translation GO:0017148 32 20 0,000 0,02667211 0,03939538 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02667211 0,03937158 ! regulation of cell killing GO:0031341 46 21 0,000 0,02798727 0,04128798 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02798727 0,04126306 ! hormone secretion GO:0046879 39 21 0,000 0,02798727 0,04123818 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02798727 0,04121332 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02798727 0,04118849 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02798727 0,04116369 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02798727 0,04113893 ! ovarian follicle development GO:0001541 39 21 0,000 0,02798727 0,04111419 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02798727 0,04108948 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02798727 0,0410648 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02798727 0,04104015 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02798727 0,04101553 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02798727 0,04099094 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02798727 0,04096638 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02798727 0,04094185 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02798727 0,04091735 ! sensory perception of pain GO:0019233 33 21 0,000 0,02798727 0,04089288 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02798727 0,04086844 ! diencephalon development GO:0021536 36 21 0,000 0,02798727 0,04084402 ! collagen fibril organization GO:0030199 62 21 0,000 0,02798727 0,04081964 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02798727 0,04079528 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02798727 0,04077096 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02798727 0,04074666 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02798727 0,04072239 ! collagen catabolic process GO:0030574 29 21 0,000 0,02798727 0,04069815 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02798727 0,04067394 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02798727 0,04064976 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02798727 0,04062561 ! actin filament-based movement GO:0030048 47 21 0,000 0,02798727 0,04060148 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02798727 0,04057739 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02930069 0,04245645 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02930069 0,04243129 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02930069 0,04240615 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02930069 0,04238104 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02930069 0,04235596 ! microtubule-based transport GO:0010970 59 22 0,000 0,02930069 0,04233092 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02930069 0,0423059 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02930069 0,04228091 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02930069 0,04225595 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02930069 0,04223102 ! cellular response to starvation GO:0009267 37 22 0,000 0,02930069 0,04220612 ! vacuolar transport GO:0007034 41 22 0,000 0,02930069 0,04218125 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02930069 0,04215641 ! fucose metabolic process GO:0006004 44 22 0,000 0,02930069 0,04213159 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02930069 0,04210681 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02930069 0,04208206 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02930069 0,04205733 ! cell aging GO:0007569 48 22 0,000 0,02930069 0,04203264 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02930069 0,04200797 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02930069 0,04198333 ! cytolysis GO:0019835 27 22 0,000 0,02930069 0,04195872 ! renal system process GO:0003014 42 22 0,000 0,02930069 0,04193414 ! vasodilation GO:0042311 40 22 0,000 0,02930069 0,04190959 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02930069 0,04188507 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02930069 0,04186057 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02930069 0,04183611 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02930069 0,04181167 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02930069 0,04178726 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02930069 0,04176288 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02930069 0,04173853 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02930069 0,04171421 ! sarcomere organization GO:0045214 32 22 0,000 0,02930069 0,04168991 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,02930069 0,04166565 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02930069 0,04164141 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02930069 0,0416172 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02930069 0,04159301 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02930069 0,04156886 ! gut development GO:0048565 44 22 0,000 0,02930069 0,04154474 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02930069 0,04152064 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02930069 0,04149657 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02930069 0,04147253 ! protein stabilization GO:0050821 41 22 0,000 0,02930069 0,04144851 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03061237 0,04327895 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03061237 0,04325391 ! gluconeogenesis GO:0006094 38 23 0,000 0,03061237 0,04322891 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03061237 0,04320394 ! viral genome replication GO:0019079 44 23 0,000 0,03061237 0,04317899 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03061237 0,04315408 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03061237 0,04312919 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03061237 0,04310433 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,03061237 0,0430795 ! axis specification GO:0009798 43 23 0,000 0,03061237 0,0430547 ! visual behavior GO:0007632 46 23 0,000 0,03061237 0,04302993 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,03061237 0,04300519 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,03061237 0,04298047 ! response to ethanol GO:0045471 47 23 0,000 0,03061237 0,04295578 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03061237 0,04293112 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03061237 0,04290649 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03061237 0,04288189 ! peroxisome organization GO:0007031 43 23 0,000 0,03061237 0,04285732 ! lysosome organization GO:0007040 47 23 0,000 0,03061237 0,04283277 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,03061237 0,04280825 ! vesicle targeting GO:0006903 49 23 0,000 0,03061237 0,04278376 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03061237 0,0427593 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03061237 0,04273487 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03061237 0,04271046 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03061237 0,04268608 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,03061237 0,04266173 ! DNA modification GO:0006304 36 23 0,000 0,03061237 0,04263741 ! fatty acid transport GO:0015908 47 23 0,000 0,03061237 0,04261312 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,03061237 0,04258885 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03061237 0,04256461 ! hormone transport GO:0009914 41 23 0,000 0,03061237 0,0425404 ! cell-cell recognition GO:0009988 28 23 0,000 0,03061237 0,04251621 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03061237 0,04249206 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03061237 0,04246793 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03061237 0,04244382 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03192232 0,04423495 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,03192232 0,04420987 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03192232 0,04418483 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03192232 0,04415981 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03192232 0,04413481 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03192232 0,04410985 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03192232 0,04408492 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03192232 0,04406001 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03192232 0,04403513 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,03192232 0,04401028 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03192232 0,04398546 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03192232 0,04396066 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,03192232 0,0439359 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03192232 0,04391116 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03192232 0,04388645 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,03192232 0,04386176 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03192232 0,04383711 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03192232 0,04381248 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,03192232 0,04378788 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03192232 0,04376331 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03192232 0,04373876 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03192232 0,04371425 ! membrane depolarization GO:0051899 45 24 0,000 0,03192232 0,04368976 ! pallium development GO:0021543 56 24 0,000 0,03192232 0,04366529 ! oogenesis GO:0048477 44 24 0,000 0,03192232 0,04364086 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03192232 0,04361645 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03192232 0,04359207 ! platelet activation GO:0030168 41 24 0,000 0,03192232 0,04356772 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03192232 0,04354339 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03192232 0,04351909 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03192232 0,04349482 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03192232 0,04347058 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03192232 0,04344636 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03192232 0,04342217 ! regulation of amine transport GO:0051952 41 24 0,000 0,03192232 0,04339801 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,03192232 0,04337387 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03323053 0,04512628 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03323053 0,04510121 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,03323053 0,04507617 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03323053 0,04505116 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03323053 0,04502617 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03323053 0,04500121 ! phototransduction GO:0007602 37 25 0,000 0,03323053 0,04497628 ! keratinization GO:0031424 37 25 0,000 0,03323053 0,04495137 ! vasculogenesis GO:0001570 49 25 0,000 0,03323053 0,0449265 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03323053 0,04490165 ! vacuole organization GO:0007033 49 25 0,000 0,03323053 0,04487683 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03323053 0,04485203 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03323053 0,04482727 ! receptor metabolic process GO:0043112 53 25 0,000 0,03323053 0,04480253 ! chromosome condensation GO:0030261 48 25 0,000 0,03323053 0,04477782 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03323053 0,04475313 ! regulation of behavior GO:0050795 48 25 0,000 0,03323053 0,04472847 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03323053 0,04470384 ! interaction with host GO:0051701 66 25 0,000 0,03323053 0,04467924 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03323053 0,04465467 ! immunoglobulin production GO:0002377 62 25 0,000 0,03323053 0,04463012 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03323053 0,04460559 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03323053 0,0445811 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03323053 0,04455663 ! liver development GO:0001889 55 25 0,000 0,03323053 0,04453219 ! protein tetramerization GO:0051262 57 25 0,000 0,03323053 0,04450777 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03453701 0,04623228 ! myelination GO:0042552 50 26 0,000 0,03453701 0,04620696 ! initiation of viral infection GO:0019059 60 26 0,000 0,03453701 0,04618167 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03453701 0,04615641 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03453701 0,04613117 ! molting cycle process GO:0022404 52 26 0,000 0,03453701 0,04610597 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03453701 0,04608078 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03453701 0,04605563 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03453701 0,04603051 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03453701 0,04600541 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03453701 0,04598034 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03453701 0,04595529 ! digestive system process GO:0022600 49 26 0,000 0,03453701 0,04593028 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03453701 0,04590529 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03453701 0,04588032 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,03453701 0,04585539 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03453701 0,04583048 ! osteoblast differentiation GO:0001649 63 26 0,000 0,03453701 0,0458056 ! neural crest cell development GO:0014032 59 26 0,000 0,03453701 0,04578075 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03453701 0,04575592 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03453701 0,04573112 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03453701 0,04570635 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03453701 0,0456816 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03453701 0,04565688 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03453701 0,04563219 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03453701 0,04560752 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03453701 0,04558288 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03453701 0,04555827 ! blastocyst development GO:0001824 50 26 0,000 0,03453701 0,04553368 ! telomere organization GO:0032200 46 26 0,000 0,03453701 0,04550912 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03453701 0,04548459 ! neural tube closure GO:0001843 58 26 0,000 0,03453701 0,04546008 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,03453701 0,0454356 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03453701 0,04541115 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03453701 0,04538672 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03584176 0,04707604 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03584176 0,04705074 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03584176 0,04702547 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03584176 0,04700023 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03584176 0,04697502 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03584176 0,04694983 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03584176 0,04692467 ! iron ion transport GO:0006826 65 27 0,000 0,03584176 0,04689953 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03584176 0,04687443 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03584176 0,04684935 ! tube lumen formation GO:0035148 59 27 0,000 0,03584176 0,04682429 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03584176 0,04679927 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03584176 0,04677427 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03584176 0,04674929 ! response to starvation GO:0042594 47 27 0,000 0,03584176 0,04672435 ! response to toxin GO:0009636 49 27 0,000 0,03584176 0,04669943 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03584176 0,04667454 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03584176 0,04664967 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03584176 0,04662483 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03584176 0,04660002 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03584176 0,04657523 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03584176 0,04655047 ! neuron fate commitment GO:0048663 52 28 0,000 0,03714479 0,04821717 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03714479 0,04819157 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03714479 0,04816599 ! vesicle docking GO:0048278 55 28 0,000 0,03714479 0,04814044 ! circadian rhythm GO:0007623 56 28 0,000 0,03714479 0,04811491 ! dendrite development GO:0016358 67 28 0,000 0,03714479 0,04808941 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03714479 0,04806394 ! fat cell differentiation GO:0045444 57 28 0,000 0,03714479 0,0480385 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03714479 0,04801308 ! sperm motility GO:0030317 37 28 0,000 0,03714479 0,04798769 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03714479 0,04796233 ! base-excision repair GO:0006284 41 28 0,000 0,03714479 0,04793699 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03714479 0,04791168 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03714479 0,0478864 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03714479 0,04786114 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03714479 0,04783591 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03714479 0,04781071 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03714479 0,04778553 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03714479 0,04776038 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03714479 0,04773526 ! lipid oxidation GO:0034440 48 28 0,000 0,03714479 0,04771016 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03714479 0,04768509 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03714479 0,04766004 ! translational initiation GO:0006413 66 29 0,000 0,03844609 0,04930383 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03844609 0,04927797 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03844609 0,04925213 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03844609 0,04922631 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03844609 0,04920053 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03844609 0,04917477 ! primary neural tube formation GO:0014020 61 29 0,000 0,03844609 0,04914903 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03844609 0,04912333 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03844609 0,04909765 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03844609 0,049072 ! somitogenesis GO:0001756 52 29 0,000 0,03844609 0,04904637 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03844609 0,04902077 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03844609 0,0489952 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03844609 0,04896966 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03844609 0,04894414 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03974567 0,05057223 ! phenol metabolic process GO:0018958 56 30 0,000 0,03974567 0,0505459 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03974567 0,0505196 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03974567 0,05049333 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03974567 0,05046709 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03974567 0,05044087 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03974567 0,05041468 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03974567 0,05038852 ! acute-phase response GO:0006953 50 30 0,000 0,03974567 0,05036239 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03974567 0,05033628 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03974567 0,0503102 ! myofibril assembly GO:0030239 50 30 0,000 0,03974567 0,05028414 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03974567 0,05025812 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03974567 0,05023212 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03974567 0,05020614 ! cell fate determination GO:0001709 64 30 0,000 0,03974567 0,0501802 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03974567 0,05015428 ! phospholipid transport GO:0015914 65 30 0,000 0,03974567 0,05012838 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03974567 0,05010252 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03974567 0,05007668 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03974567 0,05005087 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03974567 0,05002508 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03974567 0,04999932 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,03974567 0,04997359 ! regulation of coagulation GO:0050818 52 30 0,000 0,03974567 0,04994788 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,04104353 0,05155237 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,04104353 0,05152587 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,04104353 0,05149941 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,04104353 0,05147297 ! cell junction assembly GO:0034329 85 31 0,000 0,04104353 0,05144656 ! regulation of innate immune response GO:0045088 57 31 0,000 0,04104353 0,05142018 ! ovulation cycle process GO:0022602 55 31 0,000 0,04104353 0,05139382 ! peptide transport GO:0015833 60 31 0,000 0,04104353 0,0513675 ! male gonad development GO:0008584 56 31 0,000 0,04104353 0,05134119 ! iron ion homeostasis GO:0055072 60 31 0,000 0,04104353 0,05131492 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,04104353 0,05128867 ! detection of light stimulus GO:0009583 44 31 0,000 0,04104353 0,05126245 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,04104353 0,05123625 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,04104353 0,05121009 ! natural killer cell activation GO:0030101 50 31 0,000 0,04104353 0,05118395 ! ensheathment of neurons GO:0007272 64 31 0,000 0,04104353 0,05115783 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,04104353 0,05113174 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,04104353 0,05110568 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,04104353 0,05107965 ! eye morphogenesis GO:0048592 65 31 0,000 0,04104353 0,05105364 ! response to heat GO:0009408 54 31 0,000 0,04104353 0,05102766 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,04104353 0,0510017 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,04233968 0,05258558 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,04233968 0,05255886 ! collagen metabolic process GO:0032963 49 32 0,000 0,04233968 0,05253216 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,04233968 0,0525055 ! spindle organization GO:0007051 50 32 0,000 0,04233968 0,05247886 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,04233968 0,05245225 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,04233968 0,05242566 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,04233968 0,0523991 ! muscle cell development GO:0055001 52 32 0,000 0,04233968 0,05237257 ! mesoderm formation GO:0001707 73 32 0,000 0,04233968 0,05234607 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,04233968 0,05231959 ! ovulation cycle GO:0042698 57 32 0,000 0,04233968 0,05229314 ! peripheral nervous system development GO:0007422 68 32 0,000 0,04233968 0,05226671 ! hindbrain development GO:0030902 65 32 0,000 0,04233968 0,05224032 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,04233968 0,05221395 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,04233968 0,0521876 ! gene silencing GO:0016458 71 32 0,000 0,04233968 0,05216128 ! regulation of pH GO:0006885 56 33 0,000 0,0436341 0,05372889 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,0436341 0,05370182 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,0436341 0,05367478 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,0436341 0,05364777 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,0436341 0,05362078 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,0436341 0,05359382 ! response to ionizing radiation GO:0010212 74 33 0,000 0,0436341 0,05356689 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,0436341 0,05353999 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,0436341 0,05351311 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,0436341 0,05348626 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,0436341 0,05345943 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,0436341 0,05343264 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,0436341 0,05340587 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04492682 0,05496055 ! post-embryonic development GO:0009791 76 34 0,000 0,04492682 0,05493304 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04492682 0,05490556 ! cholesterol transport GO:0030301 62 34 0,000 0,04492682 0,05487811 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04492682 0,05485068 ! spliceosome assembly GO:0000245 75 34 0,000 0,04492682 0,05482328 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04492682 0,05479591 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04492682 0,05476857 ! formation of primary germ layer GO:0001704 76 34 0,000 0,04492682 0,05474125 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,04492682 0,05471396 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04492682 0,0546867 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04492682 0,05465947 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,04492682 0,05463226 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,04621782 0,0561742 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,04621782 0,05614626 ! negative regulation of secretion GO:0051048 68 35 0,000 0,04621782 0,05611836 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,04621782 0,05609048 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,04621782 0,05606263 ! membrane docking GO:0022406 69 35 0,000 0,04621782 0,05603481 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,04621782 0,05600701 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,04621782 0,05597924 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,04621782 0,0559515 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,04621782 0,05592379 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,04621782 0,05589611 ! ceramide metabolic process GO:0006672 72 35 0,000 0,04621782 0,05586845 ! telencephalon development GO:0021537 81 35 0,000 0,04621782 0,05584082 ! sterol transport GO:0015918 63 35 0,000 0,04621782 0,05581321 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,04621782 0,05578564 ! placenta development GO:0001890 53 35 0,000 0,04621782 0,05575809 ! vesicle localization GO:0051648 70 35 0,000 0,04621782 0,05573057 ! regulation of muscle development GO:0048634 82 36 0,000 0,04750711 0,05725697 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04750711 0,05722874 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,04750711 0,05720053 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04750711 0,05717235 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04750711 0,0571442 ! protein targeting to membrane GO:0006612 75 36 0,000 0,04750711 0,05711608 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04750711 0,05708799 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,04750711 0,05705992 ! aerobic respiration GO:0009060 56 36 0,000 0,04750711 0,05703188 ! cytokine production GO:0001816 68 36 0,000 0,04750711 0,05700387 ! embryonic organ development GO:0048568 67 36 0,000 0,04750711 0,05697589 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04750711 0,05694793 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,04750711 0,05692 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,0487947 0,05843405 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,0487947 0,05840542 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,0487947 0,05837681 ! sister chromatid segregation GO:0000819 65 37 0,000 0,0487947 0,05834824 ! actomyosin structure organization GO:0031032 68 37 0,000 0,0487947 0,05831969 ! cell junction organization GO:0034330 96 37 0,000 0,0487947 0,05829118 ! tissue remodeling GO:0048771 78 37 0,000 0,0487947 0,05826269 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,0487947 0,05823422 ! female gonad development GO:0008585 71 37 0,000 0,0487947 0,05820579 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,0487947 0,05817738 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,0487947 0,058149 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,0487947 0,05812065 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,0487947 0,05809233 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,05008058 0,05959419 ! meiosis I GO:0007127 74 38 0,000 0,05008058 0,05956517 ! organic anion transport GO:0015711 82 38 0,000 0,05008058 0,05953619 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,05008058 0,05950723 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,05008058 0,0594783 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,05008058 0,0594494 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,05008058 0,05942053 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,05008058 0,05939168 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,05008058 0,05936287 ! regulation of protein stability GO:0031647 77 38 0,000 0,05008058 0,05933408 ! spermatid development GO:0007286 69 38 0,000 0,05008058 0,05930532 ! pigment metabolic process GO:0042440 87 38 0,000 0,05008058 0,05927658 ! neural tube formation GO:0001841 79 38 0,000 0,05008058 0,05924788 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,05136477 0,06073772 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,05136477 0,06070833 ! negative regulation of binding GO:0051100 71 39 0,000 0,05136477 0,06067898 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,05136477 0,06064965 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,05136477 0,06062035 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,05136477 0,06059108 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,05136477 0,06056183 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,05136477 0,06053262 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,05136477 0,06050343 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,05136477 0,06047428 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,05136477 0,06044515 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,05264725 0,06192452 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,05264725 0,06189472 ! learning GO:0007612 82 40 0,000 0,05264725 0,06186495 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,05264725 0,0618352 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,05264725 0,06180549 ! lipid homeostasis GO:0055088 75 40 0,000 0,05264725 0,0617758 ! mismatch repair GO:0006298 58 40 0,000 0,05264725 0,06174615 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,05264725 0,06171652 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,05264725 0,06168692 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,05264725 0,06165735 ! RNA export from nucleus GO:0006405 61 41 0,000 0,05392803 0,06312706 ! mRNA catabolic process GO:0006402 79 41 0,000 0,05392803 0,06309683 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,05392803 0,06306662 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,05392803 0,06303645 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,05392803 0,0630063 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,05392803 0,06297618 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,05392803 0,06294609 ! feeding behavior GO:0007631 69 41 0,000 0,05392803 0,06291603 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,05392803 0,062886 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,05392803 0,062856 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,05392803 0,06282603 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,05392803 0,06279608 ! spermatid differentiation GO:0048515 73 41 0,000 0,05392803 0,06276616 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,05392803 0,06273627 ! RNA modification GO:0009451 64 41 0,000 0,05392803 0,06270641 ! ear morphogenesis GO:0042471 64 42 0,000 0,05520712 0,06416317 ! organic ether metabolic process GO:0018904 59 42 0,000 0,05520712 0,06413266 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,05520712 0,06410218 ! T cell differentiation GO:0030217 93 42 0,000 0,05520712 0,06407173 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,05520712 0,0640413 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,05520712 0,06401091 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,05520712 0,06398054 ! regulation of protein secretion GO:0050708 77 42 0,000 0,05520712 0,06395021 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,05520712 0,0639199 ! cytokinesis GO:0000910 84 42 0,000 0,05520712 0,06388962 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,05520712 0,06385937 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,05648451 0,06530604 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,05648451 0,06527515 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,05648451 0,06524429 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05648451 0,06521345 ! regulation of tube size GO:0035150 76 43 0,000 0,05648451 0,06518265 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,05648451 0,06515187 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,05648451 0,06512112 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05648451 0,06509041 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,05648451 0,06505972 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05648451 0,06502906 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05648451 0,06499843 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05648451 0,06496783 ! segmentation GO:0035282 78 43 0,000 0,05648451 0,06493725 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05648451 0,06490671 ! neuron migration GO:0001764 85 43 0,000 0,05648451 0,06487619 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,05648451 0,06484571 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05776022 0,0662791 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,05776022 0,06624798 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,05776022 0,0662169 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,05776022 0,06618584 ! hexose transport GO:0008645 68 44 0,000 0,05776022 0,06615481 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,05776022 0,06612381 ! phagocytosis GO:0006909 105 44 0,000 0,05776022 0,06609284 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05776022 0,06606189 ! double-strand break repair GO:0006302 85 44 0,000 0,05776022 0,06603098 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05903423 0,06745586 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,05903423 0,06742432 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,05903423 0,06739281 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,05903423 0,06736134 ! biopolymer methylation GO:0043414 91 45 0,000 0,05903423 0,06732989 ! B cell differentiation GO:0030183 124 45 0,000 0,05903423 0,06729847 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05903423 0,06726708 ! female gamete generation GO:0007292 71 45 0,000 0,05903423 0,06723572 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05903423 0,06720439 ! polyol metabolic process GO:0019751 77 45 0,000 0,05903423 0,06717309 ! maintenance of location in cell GO:0051651 101 45 0,000 0,05903423 0,06714182 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,06030656 0,06855697 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,06030656 0,06852508 ! glycolysis GO:0006096 71 46 0,000 0,06030656 0,06849322 ! leukocyte migration GO:0050900 75 46 0,000 0,06030656 0,06846139 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,06030656 0,0684296 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,06030656 0,06839783 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,06030656 0,06836609 ! pigmentation GO:0043473 103 46 0,000 0,06030656 0,06833438 ! neural tube development GO:0021915 91 47 0,000 0,0615772 0,06974182 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,0615772 0,0697095 ! positive regulation of defense response GO:0031349 88 48 0,000 0,06284616 0,07111309 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,06284616 0,07108017 ! mitochondrial transport GO:0006839 94 48 0,000 0,06284616 0,07104728 ! cellular component disassembly GO:0022411 89 48 0,000 0,06284616 0,07101442 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,06284616 0,07098159 ! endosome transport GO:0016197 127 48 0,000 0,06284616 0,07094879 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,06284616 0,07091601 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,06284616 0,07088327 ! male sex differentiation GO:0046661 93 48 0,000 0,06284616 0,07085056 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,06284616 0,07081788 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,06284616 0,07078523 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,06284616 0,07075261 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,06284616 0,07072002 ! methylation GO:0032259 97 48 0,000 0,06284616 0,07068746 ! response to calcium ion GO:0051592 94 49 0,000 0,06411344 0,07207968 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,06411344 0,07204652 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,06411344 0,0720134 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,06411344 0,0719803 ! JNK cascade GO:0007254 106 49 0,000 0,06411344 0,07194724 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,06411344 0,0719142 ! regulation of action potential GO:0001508 102 50 0,000 0,06537904 0,07330014 ! regulation of ion transport GO:0043269 86 50 0,000 0,06537904 0,07326652 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,06537904 0,07323292 ! endocrine system development GO:0035270 109 50 0,000 0,06537904 0,07319936 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,06537904 0,07316583 ! activation of caspase activity GO:0006919 95 50 0,000 0,06537904 0,07313233 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,06537904 0,07309886 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,06537904 0,07306542 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,06537904 0,07303201 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,06537904 0,07299863 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,06537904 0,07296528 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,06664297 0,07434191 ! viral infectious cycle GO:0019058 104 51 0,000 0,06664297 0,07430798 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,06664297 0,07427408 ! peptide metabolic process GO:0006518 80 51 0,000 0,06664297 0,07424021 ! response to temperature stimulus GO:0009266 84 51 0,000 0,06664297 0,07420637 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,06664297 0,07417256 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,06664297 0,07413879 ! positive regulation of binding GO:0051099 88 52 0,000 0,06790522 0,07550863 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,06790522 0,07547428 ! Notch signaling pathway GO:0007219 111 52 0,000 0,06790522 0,07543995 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,06790522 0,07540566 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,06790522 0,0753714 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,06790522 0,07533717 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,06790522 0,07530298 ! excretion GO:0007588 87 52 0,000 0,06790522 0,07526881 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,06790522 0,07523468 ! histone modification GO:0016570 104 52 0,000 0,06790522 0,07520057 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,06790522 0,0751665 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,06790522 0,07513245 ! amino acid activation GO:0043038 98 52 0,000 0,06790522 0,07509844 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,0691658 0,07645795 ! positive regulation of growth GO:0045927 96 53 0,000 0,0691658 0,07642336 ! inner ear development GO:0048839 89 53 0,000 0,0691658 0,07638882 ! chromatin remodeling GO:0006338 122 53 0,000 0,0691658 0,0763543 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,0691658 0,07631981 ! vesicle organization GO:0016050 127 53 0,000 0,0691658 0,07628535 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,0691658 0,07625093 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,0691658 0,07621654 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,07042472 0,07756879 ! regulation of translational initiation GO:0006446 87 54 0,000 0,07042472 0,07753384 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,07042472 0,07749891 ! neuromuscular process GO:0050905 107 54 0,000 0,07042472 0,07746402 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,07042472 0,07742915 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,07042472 0,07739432 ! membrane fusion GO:0006944 122 54 0,000 0,07042472 0,07735952 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,07042472 0,07732476 ! covalent chromatin modification GO:0016569 115 54 0,000 0,07042472 0,07729002 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,07042472 0,07725531 ! regulation of cell shape GO:0008360 142 54 0,000 0,07042472 0,07722064 ! RNA catabolic process GO:0006401 103 55 0,000 0,07168196 0,07856394 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,07168196 0,07852871 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,07168196 0,07849351 ! cell recognition GO:0008037 98 55 0,000 0,07168196 0,07845835 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,07168196 0,07842321 ! cell maturation GO:0048469 107 55 0,000 0,07168196 0,07838811 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,07168196 0,07835303 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,07168196 0,07831799 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,07293754 0,07965418 ! glucose catabolic process GO:0006007 88 56 0,000 0,07293754 0,07961859 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,07293754 0,07958303 ! RNA elongation GO:0006354 90 56 0,000 0,07293754 0,0795475 ! chloride transport GO:0006821 102 57 0,000 0,07419146 0,08087895 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,07419146 0,08084288 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,07419146 0,08080683 ! regulation of actin filament length GO:0030832 118 58 0,000 0,07544371 0,08213413 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,07544371 0,08209755 ! aging GO:0007568 112 58 0,000 0,07544371 0,08206099 ! gastrulation GO:0007369 122 58 0,000 0,07544371 0,08202447 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,07544371 0,08198799 ! maintenance of location GO:0051235 124 58 0,000 0,07544371 0,08195153 ! nuclear export GO:0051168 110 59 0,000 0,07669431 0,08327298 ! establishment of organelle localization GO:0051656 122 59 0,000 0,07669431 0,08323598 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,07794325 0,08455389 ! DNA catabolic process GO:0006308 94 60 0,000 0,07794325 0,08451636 ! regulation of endocytosis GO:0030100 104 60 0,000 0,07794325 0,08447887 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,07794325 0,0844414 ! adult behavior GO:0030534 104 60 0,000 0,07794325 0,08440397 ! positive regulation of secretion GO:0051047 110 61 0,000 0,07919054 0,08571665 ! regulation of cellular component size GO:0032535 125 61 0,000 0,07919054 0,08567869 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,07919054 0,08564076 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,07919054 0,08560287 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,07919054 0,08556501 ! regulation of heart contraction GO:0008016 123 61 0,000 0,07919054 0,08552718 ! camera-type eye development GO:0043010 126 61 0,000 0,07919054 0,08548939 ! proton transport GO:0015992 117 61 0,000 0,07919054 0,08545163 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,07919054 0,0854139 ! viral reproductive process GO:0022415 132 62 0,000 0,08043617 0,08671914 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,08043617 0,08668089 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,08043617 0,08664267 ! tRNA processing GO:0008033 102 62 0,000 0,08043617 0,08660448 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,08043617 0,08656633 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,08168016 0,08786641 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,08168016 0,08782774 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,08168016 0,0877891 ! hydrogen transport GO:0006818 121 64 0,000 0,08292249 0,08908516 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,08292249 0,089046 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,08292249 0,08900688 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,08416319 0,09029893 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,08416319 0,09025929 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,08416319 0,09021969 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,08416319 0,09018012 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,08416319 0,09014058 ! ear development GO:0043583 114 66 0,000 0,08540223 0,09142754 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,08540223 0,0913875 ! gonad development GO:0008406 115 66 0,000 0,08540223 0,09134748 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,08540223 0,09130751 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,08663964 0,09258996 ! chromosome segregation GO:0007059 127 67 0,000 0,08663964 0,09254947 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,08663964 0,09250902 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,08663964 0,09246861 ! secondary metabolic process GO:0019748 125 67 0,000 0,08663964 0,09242823 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,08663964 0,09238788 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,08787541 0,09366475 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,08787541 0,09362391 ! hexose catabolic process GO:0019320 113 68 0,000 0,08787541 0,09358309 ! extracellular matrix organization GO:0030198 146 68 0,000 0,08787541 0,09354232 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,08787541 0,09350158 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,08787541 0,09346087 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,08787541 0,0934202 ! viral reproduction GO:0016032 142 68 0,000 0,08787541 0,09337956 ! adaptive immune response GO:0002250 126 68 0,000 0,08787541 0,09333896 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,08787541 0,0932984 ! cell projection assembly GO:0030031 138 68 0,000 0,08787541 0,09325787 ! negative regulation of cell size GO:0045792 144 69 0,000 0,08910954 0,09452653 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,08910954 0,0944855 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,08910954 0,09444451 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,08910954 0,09440355 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,08910954 0,09436263 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,08910954 0,09432175 ! developmental maturation GO:0021700 128 69 0,000 0,08910954 0,0942809 ! single fertilization GO:0007338 83 69 0,000 0,08910954 0,09424008 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,09034203 0,0955022 ! cell redox homeostasis GO:0045454 114 70 0,000 0,09034203 0,09546089 ! germ cell development GO:0007281 133 70 0,000 0,09034203 0,09541962 ! activation of immune response GO:0002253 120 70 0,000 0,09034203 0,09537838 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,09034203 0,09533718 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,09157289 0,09659438 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,09157289 0,09655269 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,09157289 0,09651103 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,09157289 0,09646942 ! carbohydrate transport GO:0008643 114 72 0,000 0,09280212 0,09772223 ! actin filament organization GO:0007015 167 72 0,000 0,09280212 0,09768013 ! B cell activation GO:0042113 179 72 0,000 0,09280212 0,09763806 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,09280212 0,09759603 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,09280212 0,09755404 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,09280212 0,09751208 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,09280212 0,09747016 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,09280212 0,09742827 ! humoral immune response GO:0006959 115 73 0,000 0,09402972 0,09867466 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,09402972 0,0986323 ! regulation of immune effector process GO:0002697 156 73 0,000 0,09402972 0,09858996 ! acute inflammatory response GO:0002526 118 74 0,000 0,0952557 0,09983255 ! amino acid transport GO:0006865 148 74 0,000 0,0952557 0,09978974 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,0952557 0,09974697 ! organelle localization GO:0051640 155 74 0,000 0,0952557 0,09970423 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,09648005 0,10094251 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,09648005 0,1008993 ! reproductive structure development GO:0048608 131 75 0,000 0,09648005 0,10085612 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,09648005 0,10081299 ! eye development GO:0001654 155 75 0,000 0,09648005 0,10076989 ! axon guidance GO:0007411 162 75 0,000 0,09648005 0,10072682 ! rhythmic process GO:0048511 142 75 0,000 0,09648005 0,10068379 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,09770278 0,10191626 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,09770278 0,10187277 ! learning or memory GO:0007611 161 76 0,000 0,09770278 0,1018293 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,09770278 0,10178588 ! regulation of blood pressure GO:0008217 134 76 0,000 0,09770278 0,10174249 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,09770278 0,10169914 ! amine catabolic process GO:0009310 136 77 0,000 0,09892389 0,10292634 ! neurotransmitter transport GO:0006836 142 77 0,000 0,09892389 0,10288253 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,09892389 0,10283875 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,09892389 0,102795 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,09892389 0,1027513 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,09892389 0,10270763 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,10014338 0,1039296 ! antigen processing and presentation GO:0019882 117 78 0,000 0,10014338 0,10388547 ! fertilization GO:0009566 99 78 0,000 0,10014338 0,10384137 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,10014338 0,10379731 ! blood coagulation GO:0007596 151 79 0,000 0,10136125 0,10501507 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,10136125 0,10497055 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,10136125 0,10492607 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,10136125 0,10488163 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,10136125 0,10483723 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,10136125 0,10479286 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,10257751 0,10600544 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,10257751 0,10596062 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,10257751 0,10591583 ! meiosis GO:0007126 143 81 0,000 0,10379216 0,10712473 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 0,000 0,10379216 0,1070795 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,10379216 0,1070343 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,1050052 0,10823953 ! protein import into nucleus GO:0006606 174 82 0,000 0,1050052 0,10819388 ! meiotic cell cycle GO:0051321 144 82 0,000 0,1050052 0,10814827 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,10621663 0,10934986 ! exocytosis GO:0006887 153 83 0,000 0,10621663 0,1093038 ! response to drug GO:0042493 149 83 0,000 0,10621663 0,10925778 ! response to oxygen levels GO:0070482 183 83 0,000 0,10621663 0,10921179 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,10621663 0,10916585 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,10621663 0,10911994 ! nuclear import GO:0051170 177 83 0,000 0,10621663 0,10907407 ! inorganic anion transport GO:0015698 156 83 0,000 0,10621663 0,10902824 ! response to metal ion GO:0010038 158 84 0,000 0,10742645 0,11022378 ! T cell activation GO:0042110 189 84 0,000 0,10742645 0,11017751 ! response to nutrient GO:0007584 135 84 0,000 0,10742645 0,11013127 ! digestion GO:0007586 130 84 0,000 0,10742645 0,11008508 ! regulation of ligase activity GO:0051340 147 84 0,000 0,10742645 0,11003892 ! hemostasis GO:0007599 165 85 0,000 0,10863467 0,11122989 ! negative regulation of transport GO:0051051 164 85 0,000 0,10863467 0,11118329 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,10863467 0,11113673 ! negative regulation of growth GO:0045926 168 85 0,000 0,10863467 0,11109021 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,10863467 0,11104373 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,10863467 0,11099729 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,10863467 0,11095088 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,10984129 0,11213635 ! regulation of lyase activity GO:0051339 169 86 0,000 0,10984129 0,11208951 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,10984129 0,11204271 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,11104631 0,1132246 ! mitochondrion organization GO:0007005 159 87 0,000 0,11104631 0,11317737 ! alcohol catabolic process GO:0046164 142 87 0,000 0,11104631 0,11313017 ! nucleosome assembly GO:0006334 126 87 0,000 0,11104631 0,11308301 ! cellular respiration GO:0045333 143 88 0,000 0,11224974 0,11426088 ! amine biosynthetic process GO:0009309 146 88 0,000 0,11224974 0,11421329 ! sensory perception of smell GO:0007608 117 88 0,000 0,11224974 0,11416574 ! chromatin assembly GO:0031497 128 88 0,000 0,11224974 0,11411823 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,11224974 0,11407076 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,11345157 0,11524415 ! regulation of DNA binding GO:0051101 167 89 0,000 0,11345157 0,11519625 ! cellular defense response GO:0006968 123 89 0,000 0,11345157 0,11514839 ! protein localization in nucleus GO:0034504 192 89 0,000 0,11345157 0,11510057 ! regulation of neurological system process GO:0031644 175 89 0,000 0,11345157 0,11505279 ! response to inorganic substance GO:0010035 173 90 0,000 0,1146518 0,11622172 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,1146518 0,11617352 ! response to unfolded protein GO:0006986 139 90 0,000 0,1146518 0,11612535 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,11585044 0,11729077 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,11585044 0,11724219 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,1170475 0,11840457 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,1170475 0,11835556 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,11824297 0,11951492 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,11824297 0,1194655 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,11824297 0,11941611 ! vitamin metabolic process GO:0006766 153 93 0,000 0,11824297 0,11936676 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,11943685 0,12052219 ! female pregnancy GO:0007565 166 94 0,000 0,11943685 0,12047243 ! sterol metabolic process GO:0016125 166 94 0,000 0,11943685 0,12042271 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,11943685 0,12037303 ! regulation of membrane potential GO:0042391 179 94 0,000 0,11943685 0,12032339 ! regulation of defense response GO:0031347 171 95 0,000 0,12062915 0,12147445 ! nucleosome organization GO:0034728 143 95 0,000 0,12062915 0,1214244 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,12062915 0,12137439 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,12062915 0,12132442 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,12062915 0,12127449 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,12062915 0,1212246 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,12062915 0,12117476 ! sex differentiation GO:0007548 171 96 0,000 0,12181987 0,12232057 ! response to protein stimulus GO:0051789 158 96 0,000 0,12181987 0,12227031 ! regulation of T cell activation GO:0050863 175 96 0,000 0,12181987 0,1222201 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,12300901 0,12336248 ! transcription initiation GO:0006352 171 97 0,000 0,12300901 0,12331186 ! leukocyte differentiation GO:0002521 232 98 0,000 0,12419657 0,12445128 ! forebrain development GO:0030900 210 98 0,000 0,12419657 0,12440026 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,12419657 0,12434927 ! mRNA transport GO:0051028 185 100 0,000 0,12656698 0,12667068 ! positive regulation of immune response GO:0050778 175 100 0,000 0,12656698 0,12661881 ! hormone metabolic process GO:0042445 171 100 0,000 0,12656698 0,12656698