pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1247-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 5,000 9,494E-14 2,319E-10 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 2,127E-07 2,599E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 3,019E-07 2,458E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 8,421E-07 5,143E-04 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 2,277E-06 1,112E-03 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 2,468E-06 1,005E-03 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 3,284E-06 1,146E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 5,484E-06 1,675E-03 GO:0060538|skeletal muscle organ development, ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 6,756E-06 1,834E-03 ! myoblast differentiation GO:0045445 50 17 2,000 1,006E-05 2,458E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,205E-05 2,676E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 1,428E-05 2,908E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,677E-05 3,152E-03 ! pancreas development GO:0031016 40 20 2,000 1,677E-05 2,927E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 2,258E-05 3,677E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 2,351E-05 3,589E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 3,139E-05 4,511E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 3,354E-05 4,552E-03 ! fat cell differentiation GO:0045444 57 28 2,000 4,751E-05 6,109E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 5,289E-05 6,461E-03 ! regulation of adenylate cyclase activity GO:0045761 165 83 3,000 5,802E-05 6,75E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 6,169E-05 6,851E-03 ! forebrain neuron development GO:0021884 13 5 1,000 6,169E-05 6,553E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 6,169E-05 6,28E-03 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 1,000 6,169E-05 6,028E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 6,169E-05 5,797E-03 ! regulation of cyclase activity GO:0031279 168 85 3,000 6,369E-05 5,763E-03 ! regulation of cAMP biosynthetic process GO:0030817 173 86 3,000 6,667E-05 5,817E-03 ! regulation of lyase activity GO:0051339 169 86 3,000 6,667E-05 5,616E-03 ! regulation of cAMP metabolic process GO:0030814 182 89 3,000 7,622E-05 6,207E-03 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 3,000 8,311E-05 6,55E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein refolding GO:0042026 15 6 1,000 9,239E-05 7,053E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 9,239E-05 6,839E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! peptidyl-arginine modification GO:0018195 13 6 1,000 9,239E-05 6,638E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 3,000 9,825E-05 6,858E-03 ! regulation of nucleotide metabolic process GO:0006140 197 98 3,000 1,108E-04 7,522E-03 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 2,000 1,109E-04 7,32E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! forebrain neuron differentiation GO:0021879 16 7 1,000 1,291E-04 8,302E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,291E-04 8,089E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,291E-04 7,887E-03 ! behavioral response to cocaine GO:0048148 14 7 1,000 1,291E-04 7,694E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 1,291E-04 7,511E-03 ! neuron remodeling GO:0016322 16 7 1,000 1,291E-04 7,336E-03 ! vesicle fusion GO:0006906 20 7 1,000 1,291E-04 7,17E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 1,291E-04 7,01E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 1,299E-04 6,9E-03 GO:0042593|glucose homeostasis, ! regulation of hormone secretion GO:0046883 69 41 2,000 1,51E-04 7,849E-03 ! mesenchymal cell development GO:0014031 94 41 2,000 1,51E-04 7,685E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 86 42 2,000 1,623E-04 8,093E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,719E-04 8,399E-03 ! generation of neurons in the forebrain GO:0021872 18 8 1,000 1,719E-04 8,234E-03 ! male meiosis GO:0007140 9 8 1,000 1,719E-04 8,076E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 1,719E-04 7,923E-03 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 1,719E-04 7,777E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! ER overload response GO:0006983 13 8 1,000 1,719E-04 7,635E-03 ! regulation of pigmentation during development GO:0048070 25 8 1,000 1,719E-04 7,499E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 1,000 1,719E-04 7,367E-03 ! response to tropane GO:0014073 15 8 1,000 1,719E-04 7,24E-03 GO:0042220|response to cocaine, ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,719E-04 7,118E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,719E-04 6,999E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 1,719E-04 6,884E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 1,719E-04 6,773E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,131E-04 8,263E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 2,131E-04 8,134E-03 ! positive regulation of protein transport GO:0051222 80 46 2,000 2,131E-04 8,009E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 2,206E-04 8,167E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 2,206E-04 8,045E-03 ! protein homooligomerization GO:0051260 84 49 2,000 2,572E-04 9,241E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,754E-04 9,749E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,754E-04 9,61E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,754E-04 9,475E-03 ! midbrain development GO:0030901 14 10 1,000 2,754E-04 9,343E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 2,754E-04 9,215E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 3,36E-04 0,01109246 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 3,36E-04 0,01094456 ! activation of phospholipase C activity GO:0007202 110 54 2,000 3,432E-04 0,01103136 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 2,000 3,623E-04 0,01149546 ! response to UV GO:0009411 120 55 2,000 3,623E-04 0,01134808 ! skeletal muscle fiber development GO:0048741 130 56 2,000 3,821E-04 0,01181728 ! regulation of B cell proliferation GO:0030888 22 12 1,000 4,025E-04 0,01229257 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 4,025E-04 0,01214081 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 4,025E-04 0,01199275 ! histone acetylation GO:0016573 27 12 1,000 4,025E-04 0,01184826 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,025E-04 0,01170721 ! localization within membrane GO:0051668 26 12 1,000 4,025E-04 0,01156948 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 4,026E-04 0,0114378 ! muscle fiber development GO:0048747 131 57 2,000 4,026E-04 0,01130633 ! regulation of phospholipase activity GO:0010517 113 57 2,000 4,026E-04 0,01117785 ! regulation of intracellular transport GO:0032386 108 57 2,000 4,026E-04 0,01105226 ! positive regulation of lipase activity GO:0060193 115 58 2,000 4,238E-04 0,0115048 ! organelle fusion GO:0048284 36 13 1,000 4,75E-04 0,0127507 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 4,75E-04 0,0126121 ! gland morphogenesis GO:0022612 31 13 1,000 4,75E-04 0,01247649 ! positive regulation of secretion GO:0051047 110 61 2,000 4,917E-04 0,01277858 ! hair follicle morphogenesis GO:0031069 27 14 1,000 5,532E-04 0,01422626 ! lipid localization GO:0010876 32 14 1,000 5,532E-04 0,01407807 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 1,000 5,532E-04 0,01393293 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 6,373E-04 0,0158865 ! regulation of vasodilation GO:0042312 27 15 1,000 6,373E-04 0,01572603 ! regulation of lipase activity GO:0060191 137 68 2,000 6,761E-04 0,01651646 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 7,055E-04 0,01706542 ! embryonic digit morphogenesis GO:0042733 36 16 1,000 7,271E-04 0,01741561 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 7,271E-04 0,01724652 ! negative regulation of kinase activity GO:0033673 145 70 2,000 7,358E-04 0,01728401 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 8,227E-04 0,01914255 ! negative regulation of transferase activity GO:0051348 155 74 2,000 8,651E-04 0,01993744 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 9,241E-04 0,02109844 ! epidermis morphogenesis GO:0048730 43 18 1,000 9,241E-04 0,02090309 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 9,241E-04 0,02071131 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 9,241E-04 0,02052303 ! neuron maturation GO:0042551 46 19 1,000 1,031E-03 0,02269388 ! protein amino acid ADP-ribosylation GO:0006471 37 19 1,000 1,031E-03 0,02249125 ! pigmentation during development GO:0048066 42 19 1,000 1,031E-03 0,02229221 ! peptide cross-linking GO:0018149 39 19 1,000 1,031E-03 0,02209667 ! protein oligomerization GO:0051259 149 79 2,000 1,046E-03 0,0222171 ! muscle cell differentiation GO:0042692 178 81 2,000 1,124E-03 0,02367835 ! response to hypoxia GO:0001666 178 81 2,000 1,124E-03 0,02347597 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,144E-03 0,023681 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,144E-03 0,023482 ! response to alkaloid GO:0043279 38 20 1,000 1,144E-03 0,02328632 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 1,144E-03 0,02309387 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 1,144E-03 0,02290457 ! regulation of peptidase activity GO:0052547 150 82 2,000 1,165E-03 0,02313707 ! response to oxygen levels GO:0070482 183 83 2,000 1,206E-03 0,02376826 ! lipid phosphorylation GO:0046834 43 21 1,000 1,262E-03 0,02466782 ! regulation of vasoconstriction GO:0019229 40 21 1,000 1,262E-03 0,02447205 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 1,262E-03 0,02427935 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 1,292E-03 0,02466287 ! regulation of protein transport GO:0051223 165 87 2,000 1,382E-03 0,02616734 GO:0070201|regulation of establishment of protein localization, ! glutamate signaling pathway GO:0007215 48 22 1,000 1,386E-03 0,02604854 ! inactivation of MAPK activity GO:0000188 45 22 1,000 1,386E-03 0,02584969 ! central nervous system neuron development GO:0021954 47 22 1,000 1,386E-03 0,02565386 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,386E-03 0,02546098 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,386E-03 0,02527097 ! viral genome replication GO:0019079 44 23 1,000 1,516E-03 0,02742804 ! ossification GO:0001503 205 91 2,000 1,572E-03 0,02824357 ! bone development GO:0060348 206 92 2,000 1,622E-03 0,02893036 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,651E-03 0,02922345 ! central nervous system neuron differentiation GO:0021953 51 24 1,000 1,651E-03 0,02901321 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,651E-03 0,02880597 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,651E-03 0,02860167 ! membrane depolarization GO:0051899 45 24 1,000 1,651E-03 0,02840025 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,651E-03 0,02820165 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,651E-03 0,02800581 ! regulation of membrane potential GO:0042391 179 94 2,000 1,725E-03 0,02907167 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,791E-03 0,02997529 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,791E-03 0,02977138 ! vasculogenesis GO:0001570 49 25 1,000 1,791E-03 0,02957022 ! regulation of protein localization GO:0032880 188 97 2,000 1,888E-03 0,03095103 ! molting cycle process GO:0022404 52 26 1,000 1,938E-03 0,03155592 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 1,000 1,938E-03 0,03134694 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,938E-03 0,03114071 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 1,938E-03 0,03093718 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,938E-03 0,03073629 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 1,938E-03 0,03053799 ! osteoblast differentiation GO:0001649 63 26 1,000 1,938E-03 0,03034223 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,938E-03 0,03014897 ! regulation of blood coagulation GO:0030193 46 26 1,000 1,938E-03 0,02995815 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,938E-03 0,02976974 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 1,944E-03 0,0296799 ! embryonic pattern specification GO:0009880 49 27 1,000 2,089E-03 0,03170034 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 2,089E-03 0,03150466 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 2,089E-03 0,03131137 ! mitochondrial membrane organization GO:0007006 60 27 1,000 2,089E-03 0,03112045 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,246E-03 0,03325711 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 2,246E-03 0,03305676 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 2,246E-03 0,03285882 ! protein amino acid acylation GO:0043543 59 28 1,000 2,246E-03 0,03266323 ! vesicle docking GO:0048278 55 28 1,000 2,246E-03 0,03246996 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 1,000 2,409E-03 0,03461368 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,409E-03 0,03441126 ! response to organic cyclic substance GO:0014070 58 29 1,000 2,409E-03 0,0342112 ! somitogenesis GO:0001756 52 29 1,000 2,409E-03 0,03401345 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 2,577E-03 0,0361747 ! neurotransmitter secretion GO:0007269 55 30 1,000 2,577E-03 0,03596799 ! regulation of B cell activation GO:0050864 55 30 1,000 2,577E-03 0,03576363 ! regulation of coagulation GO:0050818 52 30 1,000 2,577E-03 0,03556157 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 2,75E-03 0,03773916 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 2,75E-03 0,03752833 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 2,928E-03 0,03974322 ! mesoderm formation GO:0001707 73 32 1,000 2,928E-03 0,03952364 ! BMP signaling pathway GO:0030509 71 32 1,000 2,928E-03 0,03930648 ! hindbrain development GO:0030902 65 32 1,000 2,928E-03 0,03909169 ! cholesterol homeostasis GO:0042632 60 33 1,000 3,112E-03 0,04132041 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 3,112E-03 0,04109705 ! post-embryonic development GO:0009791 76 34 1,000 3,301E-03 0,04336039 ! cholesterol transport GO:0030301 62 34 1,000 3,301E-03 0,04312851 ! formation of primary germ layer GO:0001704 76 34 1,000 3,301E-03 0,04289911 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 3,301E-03 0,04267213 ! adult locomotory behavior GO:0008344 62 34 1,000 3,301E-03 0,04244754 ! membrane docking GO:0022406 69 35 1,000 3,496E-03 0,04471176 ! mesoderm morphogenesis GO:0048332 80 35 1,000 3,496E-03 0,04447888 ! sterol transport GO:0015918 63 35 1,000 3,496E-03 0,04424842 ! calcium-mediated signaling GO:0019722 67 35 1,000 3,496E-03 0,04402034 ! odontogenesis GO:0042476 74 37 1,000 3,9E-03 0,04886163 ! tissue remodeling GO:0048771 78 37 1,000 3,9E-03 0,04861234 ! regulation of microtubule-based process GO:0032886 86 37 1,000 3,9E-03 0,04836557 ! neutral lipid metabolic process GO:0006638 54 38 1,000 4,11E-03 0,05071235 GO:0006639|acylglycerol metabolic process, ! glycogen metabolic process GO:0005977 63 38 1,000 4,11E-03 0,05045752 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 4,11E-03 0,05020523 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 4,325E-03 0,05257039 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 4,325E-03 0,05231014 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 4,546E-03 0,05470326 ! lipid homeostasis GO:0055088 75 40 1,000 4,546E-03 0,0544351 ! glycerol ether metabolic process GO:0006662 57 40 1,000 4,546E-03 0,05416957 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 4,771E-03 0,05657922 ! organic ether metabolic process GO:0018904 59 42 1,000 5,001E-03 0,0590254 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 5,237E-03 0,06150728 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 5,237E-03 0,06121299 ! hormone-mediated signaling GO:0009755 84 43 1,000 5,237E-03 0,0609215 ! segmentation GO:0035282 78 43 1,000 5,237E-03 0,06063277 ! energy reserve metabolic process GO:0006112 76 44 1,000 5,477E-03 0,06311803 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 5,477E-03 0,06282171 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 5,723E-03 0,06533048 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 5,723E-03 0,06502662 ! keratinocyte differentiation GO:0030216 81 45 1,000 5,723E-03 0,06472557 ! biopolymer methylation GO:0043414 91 45 1,000 5,723E-03 0,06442729 ! activation of adenylate cyclase activity GO:0007190 94 46 1,000 5,973E-03 0,06693829 ! pigmentation GO:0043473 103 46 1,000 5,973E-03 0,06663264 ! response to insulin stimulus GO:0032868 98 47 1,000 6,229E-03 0,06916562 ! positive regulation of cell cycle GO:0045787 96 48 1,000 6,489E-03 0,07172998 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 6,489E-03 0,07140687 ! mitochondrial transport GO:0006839 94 48 1,000 6,489E-03 0,07108666 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 6,489E-03 0,07076931 ! positive regulation of DNA binding GO:0043388 83 48 1,000 6,489E-03 0,07045478 ! methylation GO:0032259 97 48 1,000 6,489E-03 0,07014303 ! positive regulation of cyclase activity GO:0031281 106 49 1,000 6,754E-03 0,0726879 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 6,754E-03 0,07236909 ! regulation of action potential GO:0001508 102 50 1,000 7,024E-03 0,07493386 ! regulation of ossification GO:0030278 123 50 1,000 7,024E-03 0,07460807 ! positive regulation of lyase activity GO:0051349 107 50 1,000 7,024E-03 0,07428509 ! epidermal cell differentiation GO:0009913 87 50 1,000 7,024E-03 0,07396489 ! viral infectious cycle GO:0019058 104 51 1,000 7,299E-03 0,07652949 ! positive regulation of binding GO:0051099 88 52 1,000 7,579E-03 0,07912238 ! histone modification GO:0016570 104 52 1,000 7,579E-03 0,07878569 ! chromatin remodeling GO:0006338 122 53 1,000 7,863E-03 0,08139659 ! vesicle organization GO:0016050 127 53 1,000 7,863E-03 0,08105314 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 7,863E-03 0,08071258 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 94 54 1,000 8,152E-03 0,0833313 ! membrane fusion GO:0006944 122 54 1,000 8,152E-03 0,08298408 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 8,152E-03 0,08263975 ! covalent chromatin modification GO:0016569 115 54 1,000 8,152E-03 0,08229826 ! cell maturation GO:0048469 107 55 1,000 8,446E-03 0,08491495 ! regulation of protein polymerization GO:0032271 117 55 1,000 8,446E-03 0,08456693 ! regulation of bone remodeling GO:0046850 143 57 1,000 9,048E-03 0,09022487 ! positive regulation of cell migration GO:0030335 137 58 1,000 9,356E-03 0,092917 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 9,356E-03 0,09254081 ! gastrulation GO:0007369 122 58 1,000 9,356E-03 0,09216767 ! regulation of tissue remodeling GO:0034103 146 58 1,000 9,356E-03 0,09179751 ! positive regulation of organelle organization GO:0010638 108 58 1,000 9,356E-03 0,09143032 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 9,986E-03 0,09719709 ! lipid modification GO:0030258 112 60 1,000 9,986E-03 0,09681139 ! adult behavior GO:0030534 104 60 1,000 9,986E-03 0,09642873 ! viral reproductive process GO:0022415 132 62 1,000 0,01063454 0,10228416 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,01096549 0,10505367 ! regulation of mitosis GO:0007088 112 63 1,000 0,01096549 0,10464331 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 0,01096549 0,10423613 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,01130095 0,10700862 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,01130095 0,10659546 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,0116409 0,10937972 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,01198532 0,11218444 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,01233418 0,11500916 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,01233418 0,11457187 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01245785 0,11528231 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01245785 0,11484728 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01245785 0,11441553 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01245785 0,113987 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01245785 0,11356168 ! neuron fate determination GO:0048664 7 5 0,000 0,01245785 0,11313952 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01245785 0,11272048 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01245785 0,11230454 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01245785 0,11189166 ! polyol transport GO:0015791 12 5 0,000 0,01245785 0,1114818 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01245785 0,11107493 ! response to superoxide GO:0000303 10 5 0,000 0,01245785 0,11067102 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01245785 0,11027004 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01245785 0,10987195 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01245785 0,10947673 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01245785 0,10908434 ! female meiosis GO:0007143 10 5 0,000 0,01245785 0,10869475 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01245785 0,10830794 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01245785 0,10792387 ! hypothalamus development GO:0021854 9 5 0,000 0,01245785 0,10754251 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01245785 0,10716384 ! cobalt ion transport GO:0006824 11 5 0,000 0,01245785 0,10678783 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01245785 0,10641444 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01245785 0,10604366 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01245785 0,10567545 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01245785 0,10530979 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01245785 0,10494666 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01245785 0,10458601 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01245785 0,10422784 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01245785 0,10387212 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01245785 0,10351881 ! transposition GO:0032196 9 5 0,000 0,01245785 0,1031679 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01245785 0,10281936 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01245785 0,10247317 ! negative chemotaxis GO:0050919 16 5 0,000 0,01245785 0,1021293 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01245785 0,10178773 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01245785 0,10144843 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01245785 0,1011114 ! behavioral response to pain GO:0048266 10 5 0,000 0,01245785 0,10077659 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01245785 0,10044399 ! Notch receptor processing GO:0007220 11 5 0,000 0,01245785 0,10011359 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01245785 0,09978534 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01245785 0,09945925 ! micturition GO:0060073 9 5 0,000 0,01245785 0,09913528 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01245785 0,09881341 ! copulation GO:0007620 9 5 0,000 0,01245785 0,09849363 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01245785 0,0981759 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01245785 0,09786023 ! bioluminescence GO:0008218 9 5 0,000 0,01245785 0,09754657 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01245785 0,09723492 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01245785 0,09692526 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01245785 0,09661756 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01245785 0,0963118 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01245785 0,09600798 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01245785 0,09570607 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01245785 0,09540605 ! grooming behavior GO:0007625 6 5 0,000 0,01245785 0,09510791 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01245785 0,09481162 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01245785 0,09451717 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01245785 0,09422455 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01245785 0,09393374 ! response to protozoan GO:0001562 13 5 0,000 0,01245785 0,09364471 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01245785 0,09335745 ! lymph vessel development GO:0001945 10 5 0,000 0,01245785 0,09307196 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01245785 0,0927882 ! endochondral ossification GO:0001958 17 5 0,000 0,01245785 0,09250617 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01245785 0,09222585 ! single strand break repair GO:0000012 8 5 0,000 0,01245785 0,09194722 ! parathyroid gland development GO:0060017 14 5 0,000 0,01245785 0,09167027 ! anagen GO:0042640 7 5 0,000 0,01245785 0,09139499 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01245785 0,09112135 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01245785 0,09084934 ! cytokine secretion GO:0050663 15 5 0,000 0,01245785 0,09057896 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01245785 0,09031018 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01245785 0,09004299 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01245785 0,08977738 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01245785 0,08951332 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01245785 0,08925082 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01245785 0,08898985 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01245785 0,08873041 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01245785 0,08847247 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01245785 0,08821603 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01245785 0,08796107 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01245785 0,08770758 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01245785 0,08745555 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01245785 0,08720496 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01245785 0,0869558 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01245785 0,08670806 ! microvillus organization GO:0032528 8 5 0,000 0,01245785 0,08646173 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01245785 0,0862168 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01245785 0,08597325 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01245785 0,08573107 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01245785 0,08549025 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01245785 0,08525078 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01245785 0,08501265 ! polyol catabolic process GO:0046174 9 5 0,000 0,01245785 0,08477585 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01245785 0,08454036 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01245785 0,08430618 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01245785 0,08407329 ! muscle cell migration GO:0014812 8 5 0,000 0,01245785 0,08384168 ! mitochondrial fission GO:0000266 8 5 0,000 0,01245785 0,08361135 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01245785 0,08338227 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01245785 0,08315445 ! mRNA transcription GO:0009299 10 5 0,000 0,01245785 0,08292788 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01245785 0,08270253 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01245785 0,0824784 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01245785 0,08225549 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01245785 0,08203377 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01245785 0,08181325 ! monocyte activation GO:0042117 10 5 0,000 0,01245785 0,08159391 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01245785 0,08137575 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01245785 0,08115875 ! response to food GO:0032094 6 5 0,000 0,01245785 0,0809429 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01245785 0,0807282 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01245785 0,08051463 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01245785 0,08030219 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01245785 0,08009087 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01245785 0,07988066 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01245785 0,07967155 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01245785 0,07946353 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01245785 0,07925659 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01245785 0,07905073 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01245785 0,07884593 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01245785 0,0786422 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01245785 0,07843951 ! lipid glycosylation GO:0030259 7 5 0,000 0,01245785 0,07823787 ! nucleobase transport GO:0015851 6 5 0,000 0,01245785 0,07803726 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01245785 0,07783767 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01245785 0,07763911 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01245785 0,07744155 ! basic amino acid transport GO:0015802 12 5 0,000 0,01245785 0,077245 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01245785 0,07704944 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01245785 0,07685487 ! actin nucleation GO:0045010 11 5 0,000 0,01245785 0,07666129 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01245785 0,07646867 ! depurination GO:0045007 5 5 0,000 0,01245785 0,07627702 ! depyrimidination GO:0045008 10 5 0,000 0,01245785 0,07608633 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01245785 0,07589658 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01245785 0,07570779 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01245785 0,07551993 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01245785 0,075333 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01245785 0,07514699 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01245785 0,0749619 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01245785 0,07477772 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01245785 0,07459444 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01245785 0,07441205 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01245785 0,07423056 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01245785 0,07404995 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01245785 0,07387022 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01245785 0,07369136 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01245785 0,07351336 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01245785 0,07333622 ! response to arsenic GO:0046685 11 5 0,000 0,01245785 0,07315993 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01245785 0,07298448 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01245785 0,07280988 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01245785 0,07263611 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01245785 0,07246317 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01245785 0,07229105 ! response to mercury ion GO:0046689 8 5 0,000 0,01245785 0,07211974 ! response to cadmium ion GO:0046686 7 5 0,000 0,01245785 0,07194924 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01245785 0,07177955 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01245785 0,07161066 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01245785 0,07144256 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01245785 0,07127525 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01245785 0,07110872 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01245785 0,07094296 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01245785 0,07077798 ! decidualization GO:0046697 11 5 0,000 0,01245785 0,07061376 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01245785 0,0704503 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01245785 0,0702876 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01245785 0,07012565 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01245785 0,06996444 ! embryonic cleavage GO:0040016 6 5 0,000 0,01245785 0,06980397 ! peroxisome fission GO:0016559 5 5 0,000 0,01245785 0,06964423 ! histone demethylation GO:0016577 13 5 0,000 0,01245785 0,06948523 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01245785 0,06932695 ! mitotic recombination GO:0006312 9 5 0,000 0,01245785 0,06916939 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01245785 0,06901254 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01245785 0,0688564 ! metaphase plate congression GO:0051310 7 5 0,000 0,01245785 0,06870097 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01245785 0,06854624 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01245785 0,0683922 ! enteric nervous system development GO:0048484 8 5 0,000 0,01245785 0,06823886 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01245785 0,0680862 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01245785 0,06793422 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01245785 0,06778292 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01245785 0,06763229 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01245785 0,06748233 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01245785 0,06733303 ! B cell homeostasis GO:0001782 13 5 0,000 0,01245785 0,06718439 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01245785 0,06703641 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01245785 0,06688908 ! metaphase GO:0051323 11 5 0,000 0,01245785 0,06674239 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01245785 0,06659635 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01245785 0,06645094 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01245785 0,06630617 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01245785 0,06616202 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01245785 0,0660185 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01245785 0,06587561 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01245785 0,06573333 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01245785 0,06559166 ! response to redox state GO:0051775 6 5 0,000 0,01245785 0,0654506 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01245785 0,06531015 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01245785 0,0651703 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01245785 0,06503105 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01245785 0,06489239 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01245785 0,06475432 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01245785 0,06461684 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01245785 0,06447994 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01245785 0,06434362 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01245785 0,06420787 ! striatum development GO:0021756 14 5 0,000 0,01245785 0,0640727 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01245785 0,06393809 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01245785 0,06380405 ! glial cell migration GO:0008347 10 5 0,000 0,01245785 0,06367057 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01245785 0,06353764 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01245785 0,06340527 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01245785 0,06327345 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01245785 0,06314218 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01245785 0,06301145 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01245785 0,06288126 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01245785 0,06275161 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01245785 0,06262249 ! neuroprotection GO:0043526 8 5 0,000 0,01245785 0,0624939 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01245785 0,06236584 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01245785 0,0622383 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01245785 0,06211129 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01245785 0,06198479 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01245785 0,0618588 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01245785 0,06173333 GO:0051497|negative regulation of stress fiber formation, ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01245785 0,06160836 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01245785 0,0614839 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01245785 0,06135994 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01245785 0,06123648 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01245785 0,06111351 ! spindle assembly GO:0051225 6 5 0,000 0,01245785 0,06099104 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01245785 0,06086906 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01245785 0,06074757 ! protein palmitoylation GO:0018345 12 5 0,000 0,01245785 0,06062655 ! drug metabolic process GO:0017144 7 5 0,000 0,01245785 0,06050602 ! stem cell division GO:0017145 11 5 0,000 0,01245785 0,06038597 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01245785 0,0602664 ! organ regeneration GO:0031100 7 5 0,000 0,01245785 0,06014729 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01245785 0,06002866 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01245785 0,05991049 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,01268746 0,0608948 ! viral reproduction GO:0016032 142 68 1,000 0,01268746 0,0607754 ! negative regulation of cell size GO:0045792 144 69 1,000 0,01304513 0,06236642 ! lung development GO:0030324 165 69 1,000 0,01304513 0,06224461 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,01304513 0,06212328 ! developmental maturation GO:0021700 128 69 1,000 0,01304513 0,06200241 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,01377355 0,06533744 ! respiratory tube development GO:0030323 171 72 1,000 0,01414426 0,06696593 ! appendage morphogenesis GO:0035107 150 72 1,000 0,01414426 0,06683641 GO:0035108|limb morphogenesis, ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,01414426 0,06670738 ! appendage development GO:0048736 151 73 1,000 0,01451927 0,06834406 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 0,01489855 0,06999453 ! respiratory system development GO:0060541 175 74 1,000 0,01489855 0,06986018 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01493094 0,06987796 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01493094 0,06974435 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01493094 0,06961125 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01493094 0,06947866 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01493094 0,06934657 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01493094 0,06921498 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01493094 0,06908389 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01493094 0,0689533 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01493094 0,0688232 ! response to oxygen radical GO:0000305 11 6 0,000 0,01493094 0,06869359 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01493094 0,06856447 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01493094 0,06843583 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01493094 0,06830767 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01493094 0,06817999 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01493094 0,06805279 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01493094 0,06792606 ! forebrain regionalization GO:0021871 9 6 0,000 0,01493094 0,06779981 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01493094 0,06767402 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01493094 0,0675487 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01493094 0,06742384 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01493094 0,06729944 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01493094 0,0671755 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01493094 0,06705202 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01493094 0,06692898 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01493094 0,0668064 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01493094 0,06668427 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01493094 0,06656258 ! malate metabolic process GO:0006108 13 6 0,000 0,01493094 0,06644134 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01493094 0,06632054 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01493094 0,06620017 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01493094 0,06608025 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01493094 0,06596075 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01493094 0,06584169 ! opsonization GO:0008228 8 6 0,000 0,01493094 0,06572306 ! mating behavior GO:0007617 7 6 0,000 0,01493094 0,06560485 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01493094 0,06548707 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01493094 0,06536971 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01493094 0,06525277 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01493094 0,06513624 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01493094 0,06502014 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01493094 0,06490444 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01493094 0,06478916 ! toxin metabolic process GO:0009404 11 6 0,000 0,01493094 0,06467428 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01493094 0,06455982 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01493094 0,06444575 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01493094 0,06433209 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01493094 0,06421883 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01493094 0,06410597 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01493094 0,0639935 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01493094 0,06388143 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01493094 0,06376975 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01493094 0,06365846 ! thymic T cell selection GO:0045061 16 6 0,000 0,01493094 0,06354755 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01493094 0,06343704 ! protein lipoylation GO:0009249 10 6 0,000 0,01493094 0,0633269 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01493094 0,06321715 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01493094 0,06310778 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01493094 0,06299878 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01493094 0,06289017 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01493094 0,06278192 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01493094 0,06267405 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01493094 0,06256655 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01493094 0,06245941 ! hyperosmotic response GO:0006972 10 6 0,000 0,01493094 0,06235264 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01493094 0,06224624 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01493094 0,0621402 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01493094 0,06203452 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01493094 0,0619292 ! urea metabolic process GO:0019627 7 6 0,000 0,01493094 0,06182423 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01493094 0,06171962 ! neutrophil activation GO:0042119 7 6 0,000 0,01493094 0,06161537 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01493094 0,06151146 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01493094 0,06140791 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01493094 0,0613047 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01493094 0,06120184 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01493094 0,06109932 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01493094 0,06099715 ! neuron apoptosis GO:0051402 15 6 0,000 0,01493094 0,06089532 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01493094 0,06079383 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01493094 0,06069267 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01493094 0,06059185 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01493094 0,06049137 ! carnitine transport GO:0015879 10 6 0,000 0,01493094 0,06039122 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01493094 0,0602914 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01493094 0,06019191 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01493094 0,06009275 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01493094 0,05999391 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01493094 0,0598954 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01493094 0,05979721 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01493094 0,05969934 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01493094 0,05960179 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01493094 0,05950456 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01493094 0,05940765 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01493094 0,05931105 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01493094 0,05921477 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01493094 0,05911879 ! response to UV-C GO:0010225 14 6 0,000 0,01493094 0,05902313 ! astrocyte development GO:0014002 16 6 0,000 0,01493094 0,05892778 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01493094 0,05883274 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01493094 0,058738 ! interaction with symbiont GO:0051702 14 6 0,000 0,01493094 0,05864356 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01493094 0,05854943 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01493094 0,0584556 ! response to copper ion GO:0046688 10 6 0,000 0,01493094 0,05836207 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01493094 0,05826884 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01493094 0,05817591 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01493094 0,05808327 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01493094 0,05799093 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01493094 0,05789888 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01493094 0,05780713 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01493094 0,05771566 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01493094 0,05762448 ! hair follicle maturation GO:0048820 8 6 0,000 0,01493094 0,05753359 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01493094 0,05744299 ! Schwann cell development GO:0014044 15 6 0,000 0,01493094 0,05735267 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01493094 0,05726263 ! response to pheromone GO:0019236 6 6 0,000 0,01493094 0,05717288 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01493094 0,05708341 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01493094 0,05699421 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01493094 0,0569053 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01493094 0,05681666 ! subpallium development GO:0021544 15 6 0,000 0,01493094 0,0567283 ! neural tube patterning GO:0021532 8 6 0,000 0,01493094 0,05664021 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01493094 0,0565524 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01493094 0,05646486 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01493094 0,05637758 ! G2 phase GO:0051319 16 6 0,000 0,01493094 0,05629058 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01493094 0,05620385 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01493094 0,05611738 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01493094 0,05603118 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01493094 0,05594524 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01493094 0,05585957 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01493094 0,05577415 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01493094 0,055689 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01493094 0,05560411 ! receptor internalization GO:0031623 11 6 0,000 0,01493094 0,05551948 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01493094 0,0554351 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01493094 0,05535098 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01493094 0,05526712 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01493094 0,0551835 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01493094 0,05510015 ! protein deubiquitination GO:0016579 16 6 0,000 0,01493094 0,05501704 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01493094 0,05493418 ! protein destabilization GO:0031648 9 6 0,000 0,01493094 0,05485157 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01493094 0,05476921 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01493094 0,0546871 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01493094 0,05460523 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01493094 0,05452361 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01493094 0,05444223 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01493094 0,0543611 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01493094 0,0542802 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01493094 0,05419955 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01493094 0,05411913 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01493094 0,05403896 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01493094 0,05395902 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01493094 0,05387932 ! neural plate development GO:0001840 9 6 0,000 0,01493094 0,05379985 ! catecholamine transport GO:0051937 9 6 0,000 0,01493094 0,05372061 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01493094 0,05364161 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01493094 0,05356284 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01493094 0,05348431 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01493094 0,053406 ! maternal placenta development GO:0001893 12 6 0,000 0,01493094 0,05332792 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01493094 0,05325007 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01493094 0,05317244 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01493094 0,05309505 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01493094 0,05301787 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01493094 0,05294092 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01493094 0,0528642 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01493094 0,05278769 GO:0055081|anion homeostasis, ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01528208 0,05395106 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,01528208 0,05387321 ! neurotransmitter transport GO:0006836 142 77 1,000 0,01606182 0,05654039 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01606182 0,05645903 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01606182 0,05637791 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01645798 0,05768556 ! blood coagulation GO:0007596 151 79 1,000 0,01685829 0,05900402 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,01726274 0,06033317 ! tRNA transcription GO:0009304 17 7 0,000 0,01739791 0,06071872 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01739791 0,0606321 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01739791 0,06054573 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01739791 0,0604596 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01739791 0,06037372 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01739791 0,06028809 ! sleep GO:0030431 16 7 0,000 0,01739791 0,06020269 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01739791 0,06011754 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01739791 0,06003263 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01739791 0,05994796 ! prostate gland development GO:0030850 14 7 0,000 0,01739791 0,05986352 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01739791 0,05977933 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01739791 0,05969537 GO:0070193|synaptonemal complex organization, ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01739791 0,05961164 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01739791 0,05952815 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01739791 0,0594449 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01739791 0,05936187 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01739791 0,05927908 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01739791 0,05919652 ! glycolipid transport GO:0046836 11 7 0,000 0,01739791 0,05911419 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01739791 0,05903209 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01739791 0,05895021 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01739791 0,05886856 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01739791 0,05878714 ! mRNA stabilization GO:0048255 18 7 0,000 0,01739791 0,05870594 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01739791 0,05862497 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01739791 0,05854422 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01739791 0,05846369 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01739791 0,05838338 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01739791 0,05830329 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01739791 0,05822343 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01739791 0,05814378 ! lipoprotein transport GO:0042953 14 7 0,000 0,01739791 0,05806435 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01739791 0,05798513 ! rhythmic behavior GO:0007622 17 7 0,000 0,01739791 0,05790613 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01739791 0,05782735 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01739791 0,05774878 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01739791 0,05767042 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01739791 0,05759228 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01739791 0,05751435 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01739791 0,05743662 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01739791 0,05735911 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01739791 0,05728181 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01739791 0,05720471 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01739791 0,05712782 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01739791 0,05705114 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01739791 0,05697467 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01739791 0,0568984 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01739791 0,05682233 ! spinal cord patterning GO:0021511 14 7 0,000 0,01739791 0,05674646 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01739791 0,0566708 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01739791 0,05659534 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01739791 0,05652008 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01739791 0,05644502 ! adrenal gland development GO:0030325 17 7 0,000 0,01739791 0,05637016 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01739791 0,0562955 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01739791 0,05622103 ! ovulation GO:0030728 10 7 0,000 0,01739791 0,05614677 ! adenohypophysis development GO:0021984 11 7 0,000 0,01739791 0,05607269 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01739791 0,05599882 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01739791 0,05592513 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01739791 0,05585164 ! microtubule nucleation GO:0007020 21 7 0,000 0,01739791 0,05577835 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01739791 0,05570524 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01739791 0,05563233 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01739791 0,05555961 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01739791 0,05548708 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01739791 0,05541473 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01739791 0,05534258 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01739791 0,05527061 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01739791 0,05519883 ! galactose metabolic process GO:0006012 13 7 0,000 0,01739791 0,05512724 ! response to dietary excess GO:0002021 8 7 0,000 0,01739791 0,05505583 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01739791 0,05498461 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01739791 0,05491357 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01739791 0,05484271 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01739791 0,05477204 ! organ growth GO:0035265 15 7 0,000 0,01739791 0,05470155 ! nucleoside transport GO:0015858 11 7 0,000 0,01739791 0,05463124 ! nucleoside salvage GO:0043174 11 7 0,000 0,01739791 0,05456111 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01739791 0,05449116 ! male sex determination GO:0030238 15 7 0,000 0,01739791 0,05442139 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01739791 0,05435179 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01739791 0,05428238 ! parturition GO:0007567 16 7 0,000 0,01739791 0,05421314 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01739791 0,05414408 ! rRNA modification GO:0000154 14 7 0,000 0,01739791 0,05407519 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01739791 0,05400648 ! spindle checkpoint GO:0031577 16 7 0,000 0,01739791 0,05393795 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01739791 0,05386958 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01739791 0,05380139 ! monocyte differentiation GO:0030224 16 7 0,000 0,01739791 0,05373338 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01739791 0,05366553 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01739791 0,05359786 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01739791 0,05353035 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01739791 0,05346302 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01739791 0,05339586 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01739791 0,05332886 ! fibrinolysis GO:0042730 11 7 0,000 0,01739791 0,05326203 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01739791 0,05319537 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01739791 0,05312888 ! eating behavior GO:0042755 8 7 0,000 0,01739791 0,05306255 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01739791 0,05299639 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01739791 0,05293039 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01739791 0,05286455 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01739791 0,05279888 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01739791 0,05273338 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01739791 0,05266803 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01739791 0,05260285 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01739791 0,05253783 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01739791 0,05247297 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01739791 0,05240826 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01739791 0,05234372 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01739791 0,05227934 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01739791 0,05221511 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01739791 0,05215105 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01739791 0,05208713 ! histone ubiquitination GO:0016574 9 7 0,000 0,01739791 0,05202338 ! regulation of meiosis GO:0040020 12 7 0,000 0,01739791 0,05195978 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01739791 0,05189634 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01739791 0,05183305 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01739791 0,05176992 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01739791 0,05170694 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01739791 0,05164411 ! transcription termination GO:0006353 14 7 0,000 0,01739791 0,05158143 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01739791 0,05151891 ! anaphase GO:0051322 18 7 0,000 0,01739791 0,05145654 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01739791 0,05139432 ! axonal fasciculation GO:0007413 19 7 0,000 0,01739791 0,05133225 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01739791 0,05127033 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01739791 0,05120856 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01739791 0,05114693 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01739791 0,05108546 ! diuresis GO:0030146 12 7 0,000 0,01739791 0,05102413 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01739791 0,05096295 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01739791 0,05090192 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01739791 0,05084103 ! antibiotic transport GO:0042891 9 7 0,000 0,01739791 0,05078029 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01739791 0,05071969 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01739791 0,05065924 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01739791 0,05059893 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01739791 0,05053877 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01739791 0,05047874 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01739791 0,05041886 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01739791 0,05035913 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01739791 0,05029953 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01739791 0,05024007 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01739791 0,05018076 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01739791 0,05012158 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01739791 0,05006255 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01739791 0,05000365 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01739791 0,04994489 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01739791 0,04988627 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01739791 0,04982779 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01739791 0,04976944 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01739791 0,04971123 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01739791 0,04965316 ! muscle adaptation GO:0043500 13 7 0,000 0,01739791 0,04959522 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01739791 0,04953741 ! retina homeostasis GO:0001895 12 7 0,000 0,01739791 0,04947975 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01739791 0,04942221 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01739791 0,04936481 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01739791 0,04930754 ! meiosis GO:0007126 143 81 1,000 0,01767131 0,05002435 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01767131 0,04996645 ! meiotic cell cycle GO:0051321 144 82 1,000 0,01808397 0,05107416 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,0185007 0,05219078 GO:0045937|positive regulation of phosphate metabolic process, ! hemostasis GO:0007599 165 85 1,000 0,01934628 0,05451322 ! negative regulation of growth GO:0045926 168 85 1,000 0,01934628 0,05445042 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01977509 0,05559325 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01985877 0,05576435 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01985877 0,05570032 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01985877 0,05563645 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01985877 0,05557272 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01985877 0,05550913 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01985877 0,05544569 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01985877 0,0553824 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01985877 0,05531925 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01985877 0,05525624 ! meiotic prophase I GO:0007128 14 8 0,000 0,01985877 0,05519338 ! response to zinc ion GO:0010043 12 8 0,000 0,01985877 0,05513066 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01985877 0,05506809 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01985877 0,05500565 ! oligopeptide transport GO:0006857 16 8 0,000 0,01985877 0,05494336 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01985877 0,0548812 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01985877 0,05481919 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01985877 0,05475732 ! signal peptide processing GO:0006465 12 8 0,000 0,01985877 0,05469558 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01985877 0,05463399 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01985877 0,05457253 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01985877 0,05451122 ! succinate metabolic process GO:0006105 17 8 0,000 0,01985877 0,05445004 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01985877 0,05438899 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01985877 0,05432809 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01985877 0,05426732 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01985877 0,05420668 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01985877 0,05414619 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01985877 0,05408582 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01985877 0,05402559 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01985877 0,0539655 ! reflex GO:0060004 17 8 0,000 0,01985877 0,05390554 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01985877 0,05384571 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01985877 0,05378601 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01985877 0,05372645 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01985877 0,05366702 ! pigment granule organization GO:0048753 17 8 0,000 0,01985877 0,05360772 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01985877 0,05354855 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01985877 0,05348951 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01985877 0,0534306 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01985877 0,05337182 ! histidine catabolic process GO:0006548 10 8 0,000 0,01985877 0,05331317 GO:0009077|histidine family amino acid catabolic process, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01985877 0,05325465 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01985877 0,05319625 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01985877 0,05313799 ! melanin metabolic process GO:0006582 17 8 0,000 0,01985877 0,05307985 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01985877 0,05302184 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01985877 0,05296396 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01985877 0,0529062 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01985877 0,05284857 ! macrophage activation GO:0042116 13 8 0,000 0,01985877 0,05279106 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01985877 0,05273368 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01985877 0,05267642 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01985877 0,05261929 ! purine salvage GO:0043101 12 8 0,000 0,01985877 0,05256228 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01985877 0,05250539 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01985877 0,05244863 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01985877 0,05239199 ! osteoblast development GO:0002076 17 8 0,000 0,01985877 0,05233547 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01985877 0,05227908 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01985877 0,0522228 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01985877 0,05216665 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01985877 0,05211062 ! response to UV-B GO:0010224 17 8 0,000 0,01985877 0,0520547 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01985877 0,05199891 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01985877 0,05194324 ! intermediate filament organization GO:0045109 12 8 0,000 0,01985877 0,05188768 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01985877 0,05183225 ! cellular extravasation GO:0045123 13 8 0,000 0,01985877 0,05177693 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01985877 0,05172173 ! response to antibiotic GO:0046677 11 8 0,000 0,01985877 0,05166665 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01985877 0,05161168 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01985877 0,05155684 ! DNA topological change GO:0006265 12 8 0,000 0,01985877 0,05150211 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01985877 0,05144749 ! melanosome transport GO:0032402 13 8 0,000 0,01985877 0,05139299 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01985877 0,05133861 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01985877 0,05128434 ! mast cell activation GO:0045576 14 8 0,000 0,01985877 0,05123018 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01985877 0,05117614 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01985877 0,05112222 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01985877 0,0510684 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01985877 0,0510147 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01985877 0,05096112 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01985877 0,05090764 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01985877 0,05085428 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01985877 0,05080103 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01985877 0,05074789 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01985877 0,05069486 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01985877 0,05064194 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01985877 0,05058914 ! response to tumor cell GO:0002347 16 8 0,000 0,01985877 0,05053644 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01985877 0,05048385 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01985877 0,05043138 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01985877 0,05037901 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01985877 0,05032675 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01985877 0,05027459 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01985877 0,05022255 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01985877 0,05017061 ! hormone catabolic process GO:0042447 17 8 0,000 0,01985877 0,05011878 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01985877 0,05006706 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01985877 0,05001545 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01985877 0,04996394 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01985877 0,04991253 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01985877 0,04986124 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01985877 0,04981004 ! adult feeding behavior GO:0008343 10 8 0,000 0,01985877 0,04975896 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01985877 0,04970797 ! ATP catabolic process GO:0006200 11 8 0,000 0,01985877 0,0496571 ! blastocyst growth GO:0001832 19 8 0,000 0,01985877 0,04960632 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01985877 0,04955565 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01985877 0,04950508 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01985877 0,04945462 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01985877 0,04940426 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01985877 0,049354 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01985877 0,04930384 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01985877 0,04925379 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01985877 0,04920384 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01985877 0,04915398 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01985877 0,04910423 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01985877 0,04905458 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01985877 0,04900503 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01985877 0,04895558 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01985877 0,04890623 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01985877 0,04885698 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01985877 0,04880783 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01985877 0,04875878 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01985877 0,04870982 ! mitochondrion organization GO:0007005 159 87 1,000 0,02020787 0,04951638 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,02064461 0,05053586 ! regulation of DNA binding GO:0051101 167 89 1,000 0,02108529 0,05156293 ! response to unfolded protein GO:0006986 139 90 1,000 0,02152989 0,05259751 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,02152989 0,05254496 ! gland development GO:0048732 220 91 1,000 0,02197837 0,05358599 ! axon extension GO:0048675 16 9 0,000 0,02231354 0,05434893 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02231354 0,0542948 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02231354 0,05424077 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02231354 0,05418686 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02231354 0,05413305 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02231354 0,05407934 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02231354 0,05402574 ! reproductive behavior GO:0019098 22 9 0,000 0,02231354 0,05397225 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02231354 0,05391887 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02231354 0,05386559 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02231354 0,05381242 ! UTP metabolic process GO:0046051 10 9 0,000 0,02231354 0,05375935 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02231354 0,05370638 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02231354 0,05365352 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02231354 0,05360076 ! artery development GO:0060840 25 9 0,000 0,02231354 0,05354811 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02231354 0,05349556 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02231354 0,05344311 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02231354 0,05339077 ! equilibrioception GO:0050957 20 9 0,000 0,02231354 0,05333853 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02231354 0,05328639 ! chemosensory behavior GO:0007635 21 9 0,000 0,02231354 0,05323435 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02231354 0,05318242 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02231354 0,05313058 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02231354 0,05307885 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02231354 0,05302721 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02231354 0,05297568 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02231354 0,05292425 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02231354 0,05287292 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02231354 0,05282168 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02231354 0,05277055 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02231354 0,05271951 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02231354 0,05266858 ! protein targeting to ER GO:0045047 25 9 0,000 0,02231354 0,05261774 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02231354 0,052567 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02231354 0,05251636 ! T cell selection GO:0045058 27 9 0,000 0,02231354 0,05246581 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02231354 0,05241536 ! glycine catabolic process GO:0006546 15 9 0,000 0,02231354 0,05236501 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02231354 0,05231476 ! endosome organization GO:0007032 20 9 0,000 0,02231354 0,0522646 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02231354 0,05221454 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02231354 0,05216457 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02231354 0,0521147 ! mannose metabolic process GO:0006013 13 9 0,000 0,02231354 0,05206493 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02231354 0,05201524 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02231354 0,05196566 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02231354 0,05191617 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02231354 0,05186677 ! receptor clustering GO:0043113 20 9 0,000 0,02231354 0,05181747 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02231354 0,05176826 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02231354 0,05171914 ! retinol metabolic process GO:0042572 20 9 0,000 0,02231354 0,05167012 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02231354 0,05162119 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02231354 0,05157235 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02231354 0,05152361 ! macrophage differentiation GO:0030225 15 9 0,000 0,02231354 0,05147495 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02231354 0,05142639 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02231354 0,05137792 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02231354 0,05132954 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02231354 0,05128126 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02231354 0,05123306 ! response to amine stimulus GO:0014075 13 9 0,000 0,02231354 0,05118495 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02231354 0,05113694 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02231354 0,05108901 ! erythrocyte development GO:0048821 17 9 0,000 0,02231354 0,05104118 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02231354 0,05099343 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02231354 0,05094577 ! renal water homeostasis GO:0003091 15 9 0,000 0,02231354 0,0508982 ! postreplication repair GO:0006301 25 9 0,000 0,02231354 0,05085072 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02231354 0,05080333 ! icosanoid secretion GO:0032309 15 9 0,000 0,02231354 0,05075603 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02231354 0,05070882 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02231354 0,05066169 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02231354 0,05061465 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02231354 0,0505677 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02231354 0,05052083 ! sterol catabolic process GO:0016127 14 9 0,000 0,02231354 0,05047405 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02231354 0,05042736 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02231354 0,05038075 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02231354 0,05033424 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02231354 0,0502878 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02231354 0,05024145 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02231354 0,05019519 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02231354 0,05014901 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02231354 0,05010292 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02231354 0,05005691 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02231354 0,05001099 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02231354 0,04996515 ! purine base metabolic process GO:0006144 25 9 0,000 0,02231354 0,04991939 ! pigment granule transport GO:0051904 17 9 0,000 0,02231354 0,04987372 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02231354 0,04982813 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02231354 0,04978263 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02231354 0,0497372 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02231354 0,04969187 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02231354 0,04964661 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02231354 0,04960143 ! mitochondrion localization GO:0051646 18 9 0,000 0,02231354 0,04955634 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,02288693 0,05078362 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,0238108 0,05278564 ! response to protein stimulus GO:0051789 158 96 1,000 0,02427842 0,0537735 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02476223 0,0547954 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02476223 0,05474581 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02476223 0,05469631 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02476223 0,0546469 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02476223 0,05459758 ! associative learning GO:0008306 21 10 0,000 0,02476223 0,05454835 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02476223 0,05449921 ! phosphate transport GO:0006817 24 10 0,000 0,02476223 0,05445015 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02476223 0,05440119 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02476223 0,05435231 ! CTP metabolic process GO:0046036 11 10 0,000 0,02476223 0,05430352 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02476223 0,05425482 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02476223 0,0542062 ! GTP metabolic process GO:0046039 11 10 0,000 0,02476223 0,05415767 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02476223 0,05410923 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02476223 0,05406088 ! social behavior GO:0035176 29 10 0,000 0,02476223 0,05401261 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02476223 0,05396442 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02476223 0,05391633 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02476223 0,05386832 ! androgen metabolic process GO:0008209 17 10 0,000 0,02476223 0,05382039 ! phospholipid efflux GO:0033700 19 10 0,000 0,02476223 0,05377255 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02476223 0,05372479 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02476223 0,05367712 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02476223 0,05362954 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02476223 0,05358204 ! lung alveolus development GO:0048286 26 10 0,000 0,02476223 0,05353462 ! pathogenesis GO:0009405 17 10 0,000 0,02476223 0,05348728 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02476223 0,05344003 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02476223 0,05339287 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02476223 0,05334578 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02476223 0,05329878 ! endoderm development GO:0007492 18 10 0,000 0,02476223 0,05325187 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02476223 0,05320503 ! arginine catabolic process GO:0006527 17 10 0,000 0,02476223 0,05315828 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02476223 0,05311161 ! proline metabolic process GO:0006560 13 10 0,000 0,02476223 0,05306502 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02476223 0,05301851 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02476223 0,05297208 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02476223 0,05292574 ! V(D)J recombination GO:0033151 34 10 0,000 0,02476223 0,05287947 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02476223 0,05283329 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02476223 0,05278719 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02476223 0,05274117 ! B cell proliferation GO:0042100 19 10 0,000 0,02476223 0,05269523 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02476223 0,05264936 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02476223 0,05260358 ! multicellular organism growth GO:0035264 19 10 0,000 0,02476223 0,05255788 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02476223 0,05251226 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02476223 0,05246671 ! ruffle organization GO:0031529 17 10 0,000 0,02476223 0,05242125 ! epithelial cell development GO:0002064 21 10 0,000 0,02476223 0,05237586 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02476223 0,05233055 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02476223 0,05228532 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02476223 0,05224017 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02476223 0,0521951 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02476223 0,0521501 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02476223 0,05210518 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02476223 0,05206034 ! motor axon guidance GO:0008045 22 10 0,000 0,02476223 0,05201558 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02476223 0,05197089 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02476223 0,05192628 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02476223 0,05188175 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02476223 0,05183729 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02476223 0,05179291 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02476223 0,0517486 ! segment specification GO:0007379 15 10 0,000 0,02476223 0,05170438 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02476223 0,05166022 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02476223 0,05161614 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02476223 0,05157214 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02476223 0,05152821 ! response to dsRNA GO:0043331 23 10 0,000 0,02476223 0,05148436 ! DNA ligation GO:0006266 18 10 0,000 0,02476223 0,05144058 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02476223 0,05139687 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02476223 0,05135324 ! melanosome localization GO:0032400 16 10 0,000 0,02476223 0,05130969 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02476223 0,0512662 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02476223 0,05122279 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02476223 0,05117946 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02476223 0,0511362 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02476223 0,05109301 ! induction of an organ GO:0001759 17 10 0,000 0,02476223 0,05104989 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02476223 0,05100685 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02476223 0,05096387 ! protein sumoylation GO:0016925 17 10 0,000 0,02476223 0,05092098 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02476223 0,05087815 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02476223 0,05083539 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02476223 0,05079271 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02476223 0,0507501 ! salivary gland development GO:0007431 28 10 0,000 0,02476223 0,05070756 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02476223 0,05066509 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02476223 0,05062269 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02476223 0,05058037 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02476223 0,05053811 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02476223 0,05049593 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02476223 0,05045381 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02476223 0,05041177 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02476223 0,05036979 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02476223 0,05032789 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02476223 0,05028605 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02476223 0,05024429 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02476223 0,05020259 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02476223 0,05016096 ! blastocyst formation GO:0001825 18 10 0,000 0,02476223 0,0501194 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02476223 0,05007791 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02476223 0,05003649 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02476223 0,04999514 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02476223 0,04995386 ! response to nicotine GO:0035094 20 10 0,000 0,02476223 0,04991264 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02476223 0,04987149 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02476223 0,04983041 ! forebrain development GO:0030900 210 98 1,000 0,02522493 0,05071975 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02720485 0,0546558 ! respiratory burst GO:0045730 17 11 0,000 0,02720485 0,05461088 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02720485 0,05456605 ! neuron fate specification GO:0048665 18 11 0,000 0,02720485 0,05452129 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02720485 0,0544766 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02720485 0,05443198 ! thyroid gland development GO:0030878 26 11 0,000 0,02720485 0,05438744 ! synapsis GO:0007129 14 11 0,000 0,02720485 0,05434297 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02720485 0,05429857 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02720485 0,05425424 ! response to pain GO:0048265 27 11 0,000 0,02720485 0,05420999 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02720485 0,05416581 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02720485 0,0541217 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02720485 0,05407766 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02720485 0,0540337 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02720485 0,0539898 ! bone resorption GO:0045453 16 11 0,000 0,02720485 0,05394598 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02720485 0,05390223 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02720485 0,05385855 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02720485 0,05381494 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02720485 0,0537714 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02720485 0,05372793 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02720485 0,05368453 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02720485 0,0536412 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02720485 0,05359794 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02720485 0,05355475 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02720485 0,05351163 ! UV protection GO:0009650 20 11 0,000 0,02720485 0,05346858 ! adult heart development GO:0007512 16 11 0,000 0,02720485 0,0534256 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02720485 0,05338269 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02720485 0,05333985 ! macroautophagy GO:0016236 19 11 0,000 0,02720485 0,05329707 ! temperature homeostasis GO:0001659 18 11 0,000 0,02720485 0,05325436 ! behavioral fear response GO:0001662 27 11 0,000 0,02720485 0,05321173 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02720485 0,05316916 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02720485 0,05312666 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02720485 0,05308422 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02720485 0,05304186 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02720485 0,05299956 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02720485 0,05295733 ! regulation of organ growth GO:0046620 14 11 0,000 0,02720485 0,05291516 ! pigment granule localization GO:0051875 20 11 0,000 0,02720485 0,05287307 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02720485 0,05283104 ! vasoconstriction GO:0042310 20 11 0,000 0,02720485 0,05278908 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02720485 0,05274718 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02720485 0,05270535 ! embryonic axis specification GO:0000578 19 11 0,000 0,02720485 0,05266359 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02720485 0,05262189 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02720485 0,05258026 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02720485 0,05253869 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02720485 0,05249719 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02720485 0,05245576 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02720485 0,05241439 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02720485 0,05237309 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02720485 0,05233185 ! prophase GO:0051324 17 11 0,000 0,02720485 0,05229067 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02720485 0,05224957 ! nucleosome positioning GO:0016584 15 11 0,000 0,02720485 0,05220852 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02720485 0,05216754 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02720485 0,05212662 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02720485 0,05208577 ! apical protein localization GO:0045176 18 11 0,000 0,02720485 0,05204499 ! acid secretion GO:0046717 20 11 0,000 0,02720485 0,05200426 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02720485 0,0519636 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02720485 0,05192301 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02720485 0,05188247 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02720485 0,051842 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02720485 0,0518016 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02720485 0,05176125 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02720485 0,05172097 ! cholesterol efflux GO:0033344 21 11 0,000 0,02720485 0,05168075 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02720485 0,0516406 ! oocyte development GO:0048599 20 11 0,000 0,02720485 0,0516005 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02720485 0,05156047 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02720485 0,0515205 ! embryonic gut development GO:0048566 19 11 0,000 0,02720485 0,05148059 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02720485 0,05144075 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02720485 0,05140096 ! activation of innate immune response GO:0002218 16 11 0,000 0,02720485 0,05136124 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02720485 0,05132158 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02720485 0,05128198 ! lysogeny GO:0030069 22 11 0,000 0,02720485 0,05124244 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02720485 0,05120296 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02720485 0,05116355 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02720485 0,05112419 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02720485 0,05108489 ! nucleus localization GO:0051647 22 11 0,000 0,02720485 0,05104566 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02964142 0,05557482 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02964142 0,05553221 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02964142 0,05548965 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02964142 0,05544716 ! virus-host interaction GO:0019048 30 12 0,000 0,02964142 0,05540474 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02964142 0,05536238 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02964142 0,05532009 ! protein complex disassembly GO:0043241 28 12 0,000 0,02964142 0,05527786 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02964142 0,05523569 ! hippocampus development GO:0021766 29 12 0,000 0,02964142 0,05519359 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02964142 0,05515156 ! T cell proliferation GO:0042098 32 12 0,000 0,02964142 0,05510959 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02964142 0,05506768 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02964142 0,05502583 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02964142 0,05498405 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02964142 0,05494233 ! drug transport GO:0015893 16 12 0,000 0,02964142 0,05490068 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02964142 0,05485909 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02964142 0,05481756 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02964142 0,05477609 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02964142 0,05473469 ! focal adhesion formation GO:0048041 37 12 0,000 0,02964142 0,05469335 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02964142 0,05465207 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02964142 0,05461086 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02964142 0,0545697 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02964142 0,05452861 ! lipid digestion GO:0044241 21 12 0,000 0,02964142 0,05448758 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02964142 0,05444661 ! entry into host cell GO:0030260 34 12 0,000 0,02964142 0,05440571 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02964142 0,05436486 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02964142 0,05432408 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02964142 0,05428336 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02964142 0,05424269 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02964142 0,05420209 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02964142 0,05416155 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02964142 0,05412107 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02964142 0,05408065 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02964142 0,0540403 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02964142 0,054 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02964142 0,05395976 ! cranial nerve development GO:0021545 23 12 0,000 0,02964142 0,05391958 ! fucose catabolic process GO:0019317 25 12 0,000 0,02964142 0,05387946 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02964142 0,0538394 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02964142 0,0537994 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02964142 0,05375946 ! zymogen activation GO:0031638 18 12 0,000 0,02964142 0,05371958 ! T cell homeostasis GO:0043029 28 12 0,000 0,02964142 0,05367976 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02964142 0,05364 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02964142 0,05360029 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02964142 0,05356065 ! oocyte differentiation GO:0009994 21 12 0,000 0,02964142 0,05352106 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02964142 0,05348153 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02964142 0,05344206 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02964142 0,05340265 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02964142 0,0533633 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02964142 0,053324 ! defense response to fungus GO:0050832 15 12 0,000 0,02964142 0,05328477 ! developmental induction GO:0031128 22 12 0,000 0,02964142 0,05324559 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02964142 0,05320646 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02964142 0,0531674 ! response to cold GO:0009409 17 12 0,000 0,02964142 0,05312839 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02964142 0,05308944 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02964142 0,05305055 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03207196 0,05735857 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03207196 0,05731661 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03207196 0,05727471 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03207196 0,05723287 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03207196 0,0571911 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03207196 0,05714938 ! peroxisomal transport GO:0043574 28 13 0,000 0,03207196 0,05710773 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03207196 0,05706613 ! cartilage condensation GO:0001502 22 13 0,000 0,03207196 0,0570246 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03207196 0,05698313 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03207196 0,05694172 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03207196 0,05690037 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03207196 0,05685907 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03207196 0,05681784 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03207196 0,05677667 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03207196 0,05673556 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03207196 0,0566945 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03207196 0,05665351 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03207196 0,05661257 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03207196 0,0565717 ! methionine metabolic process GO:0006555 31 13 0,000 0,03207196 0,05653088 ! plasma membrane organization GO:0007009 27 13 0,000 0,03207196 0,05649012 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03207196 0,05644943 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03207196 0,05640879 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03207196 0,0563682 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03207196 0,05632768 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03207196 0,05628721 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03207196 0,05624681 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,03207196 0,05620646 ! exocrine system development GO:0035272 34 13 0,000 0,03207196 0,05616617 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03207196 0,05612593 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03207196 0,05608576 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03207196 0,05604564 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,03207196 0,05600558 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,03207196 0,05596557 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03207196 0,05592563 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03207196 0,05588574 ! protein homotetramerization GO:0051289 24 13 0,000 0,03207196 0,0558459 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03207196 0,05580613 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03207196 0,05576641 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03207196 0,05572674 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03207196 0,05568714 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03207196 0,05564759 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03207196 0,05560809 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03207196 0,05556865 ! histone methylation GO:0016571 29 13 0,000 0,03207196 0,05552927 ! chromatin silencing GO:0006342 29 13 0,000 0,03207196 0,05548995 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03207196 0,05545067 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03207196 0,05541146 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03207196 0,0553723 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03207196 0,05533319 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03207196 0,05529414 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03207196 0,05525515 ! spleen development GO:0048536 24 13 0,000 0,03207196 0,05521621 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03207196 0,05517733 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03207196 0,0551385 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03207196 0,05509972 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03207196 0,055061 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03207196 0,05502233 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03207196 0,05498372 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03207196 0,05494516 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03207196 0,05490666 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03207196 0,05486821 ! insulin secretion GO:0030073 24 13 0,000 0,03207196 0,05482981 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03207196 0,05479147 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03207196 0,05475318 ! acrosome reaction GO:0007340 19 13 0,000 0,03207196 0,05471495 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03207196 0,05467676 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03207196 0,05463864 ! rRNA transcription GO:0009303 28 14 0,000 0,03449648 0,05872816 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03449648 0,05868726 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03449648 0,05864642 ! water transport GO:0006833 21 14 0,000 0,03449648 0,05860564 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03449648 0,05856491 ! non-recombinational repair GO:0000726 29 14 0,000 0,03449648 0,05852424 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03449648 0,05848363 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03449648 0,05844307 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03449648 0,05840257 ! palate development GO:0060021 32 14 0,000 0,03449648 0,05836212 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03449648 0,05832173 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03449648 0,0582814 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03449648 0,05824112 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03449648 0,0582009 ! arginine metabolic process GO:0006525 21 14 0,000 0,03449648 0,05816073 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03449648 0,05812062 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03449648 0,05808057 ! regulation of heart rate GO:0002027 25 14 0,000 0,03449648 0,05804057 ! fear response GO:0042596 34 14 0,000 0,03449648 0,05800062 ! organic alcohol transport GO:0015850 29 14 0,000 0,03449648 0,05796073 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03449648 0,0579209 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03449648 0,05788112 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03449648 0,05784139 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03449648 0,05780172 ! bone mineralization GO:0030282 18 14 0,000 0,03449648 0,0577621 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03449648 0,05772254 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03449648 0,05768303 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03449648 0,05764357 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03449648 0,05760417 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03449648 0,05756482 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03449648 0,05752553 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03449648 0,05748629 ! ribosome assembly GO:0042255 18 14 0,000 0,03449648 0,05744711 ! cerebellum development GO:0021549 23 14 0,000 0,03449648 0,05740797 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03449648 0,05736889 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03449648 0,05732987 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03449648 0,05729089 ! response to gamma radiation GO:0010332 30 14 0,000 0,03449648 0,05725197 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03449648 0,0572131 ! NADP metabolic process GO:0006739 24 14 0,000 0,03449648 0,05717429 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03449648 0,05713553 ! oxygen transport GO:0015671 22 14 0,000 0,03449648 0,05709682 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03449648 0,05705816 ! male genitalia development GO:0030539 26 14 0,000 0,03449648 0,05701956 ! regulation of RNA stability GO:0043487 33 14 0,000 0,03449648 0,056981 ! regulation of axon extension GO:0030516 43 14 0,000 0,03449648 0,0569425 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,03449648 0,05690405 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03449648 0,05686566 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,036915 0,06081142 ! lactation GO:0007595 30 15 0,000 0,036915 0,06077044 ! reproductive cellular process GO:0048610 22 15 0,000 0,036915 0,06072952 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,036915 0,06068865 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,036915 0,06064784 ! superoxide anion generation GO:0042554 22 15 0,000 0,036915 0,06060708 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,036915 0,06056638 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,036915 0,06052573 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,036915 0,06048513 ! copper ion transport GO:0006825 22 15 0,000 0,036915 0,06044459 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,036915 0,06040411 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,036915 0,06036368 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,036915 0,0603233 ! sulfate transport GO:0008272 27 15 0,000 0,036915 0,06028298 ! response to cAMP GO:0051591 25 15 0,000 0,036915 0,06024271 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,036915 0,06020249 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,036915 0,06016233 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,036915 0,06012222 ! response to hexose stimulus GO:0009746 25 15 0,000 0,036915 0,06008217 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,036915 0,06004217 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,036915 0,06000222 ! vesicle coating GO:0006901 38 15 0,000 0,036915 0,05996232 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,036915 0,05992248 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,036915 0,05988269 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,036915 0,05984296 ! regulation of exocytosis GO:0017157 26 15 0,000 0,036915 0,05980327 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,036915 0,05976364 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,036915 0,05972406 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,036915 0,05968454 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,036915 0,05964506 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,036915 0,05960564 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,036915 0,05956627 ! histone deacetylation GO:0016575 24 15 0,000 0,036915 0,05952695 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,036915 0,05948769 ! water homeostasis GO:0030104 28 15 0,000 0,036915 0,05944847 ! cofactor transport GO:0051181 30 15 0,000 0,036915 0,05940931 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,036915 0,0593702 ! muscle maintenance GO:0046716 26 15 0,000 0,036915 0,05933114 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,036915 0,05929213 ! intestinal absorption GO:0050892 31 15 0,000 0,036915 0,05925318 ! dopamine metabolic process GO:0042417 35 15 0,000 0,036915 0,05921427 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,036915 0,05917542 ! heme biosynthetic process GO:0006783 33 15 0,000 0,036915 0,05913661 ! cell killing GO:0001906 32 15 0,000 0,036915 0,05909786 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,036915 0,05905916 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,036915 0,05902051 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,036915 0,05898191 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,036915 0,05894336 ! actin filament polymerization GO:0030041 27 15 0,000 0,036915 0,05890486 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,036915 0,05886641 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03932752 0,06267262 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03932752 0,06263177 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03932752 0,06259096 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03932752 0,06255021 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03932752 0,06250952 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03932752 0,06246888 ! bone remodeling GO:0046849 28 16 0,000 0,03932752 0,06242828 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03932752 0,06238775 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03932752 0,06234726 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03932752 0,06230683 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03932752 0,06226645 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03932752 0,06222612 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03932752 0,06218584 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03932752 0,06214562 ! startle response GO:0001964 28 16 0,000 0,03932752 0,06210545 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03932752 0,06206533 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03932752 0,06202526 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03932752 0,06198525 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03932752 0,06194528 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03932752 0,06190537 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03932752 0,06186551 ! pituitary gland development GO:0021983 30 16 0,000 0,03932752 0,0618257 ! response to osmotic stress GO:0006970 27 16 0,000 0,03932752 0,06178594 ! lysosomal transport GO:0007041 31 16 0,000 0,03932752 0,06174623 ! fructose metabolic process GO:0006000 25 16 0,000 0,03932752 0,06170657 ! L-amino acid transport GO:0015807 33 16 0,000 0,03932752 0,06166696 ! stem cell development GO:0048864 46 16 0,000 0,03932752 0,06162741 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03932752 0,0615879 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03932752 0,06154845 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03932752 0,06150905 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03932752 0,06146969 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03932752 0,06143039 ! axon cargo transport GO:0008088 46 16 0,000 0,03932752 0,06139114 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03932752 0,06135194 ! DNA replication initiation GO:0006270 28 16 0,000 0,03932752 0,06131278 ! neuron recognition GO:0008038 40 16 0,000 0,03932752 0,06127368 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03932752 0,06123463 ! tissue regeneration GO:0042246 27 16 0,000 0,03932752 0,06119562 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03932752 0,06115667 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03932752 0,06111777 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03932752 0,06107891 ! biomineral formation GO:0031214 22 16 0,000 0,03932752 0,06104011 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03932752 0,06100135 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03932752 0,06096265 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03932752 0,06092399 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03932752 0,06088538 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03932752 0,06084682 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03932752 0,06080831 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03932752 0,06076985 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03932752 0,06073144 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03932752 0,06069307 ! peptide hormone processing GO:0016486 27 16 0,000 0,03932752 0,06065475 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04173407 0,06432576 ! metencephalon development GO:0022037 32 17 0,000 0,04173407 0,0642852 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04173407 0,06424469 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,04173407 0,06420424 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04173407 0,06416383 ! signal complex assembly GO:0007172 47 17 0,000 0,04173407 0,06412348 ! filopodium assembly GO:0046847 42 17 0,000 0,04173407 0,06408317 ! endothelial cell migration GO:0043542 31 17 0,000 0,04173407 0,06404292 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04173407 0,06400272 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04173407 0,06396256 ! glial cell development GO:0021782 28 17 0,000 0,04173407 0,06392246 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04173407 0,06388241 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04173407 0,06384241 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04173407 0,06380246 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04173407 0,06376256 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,04173407 0,0637227 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,04173407 0,0636829 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,04173407 0,06364315 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04173407 0,06360345 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,04173407 0,0635638 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04173407 0,06352419 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,04173407 0,06348464 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,04173407 0,06344513 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,04173407 0,06340568 ! membrane budding GO:0006900 42 17 0,000 0,04173407 0,06336627 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04173407 0,06332691 ! regulation of protein binding GO:0043393 33 17 0,000 0,04173407 0,0632876 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04173407 0,06324834 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04173407 0,06320913 ! genitalia development GO:0048806 32 17 0,000 0,04173407 0,06316997 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04173407 0,06313085 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,04173407 0,06309179 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04173407 0,06305277 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04173407 0,0630138 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,04173407 0,06297488 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04173407 0,062936 ! steroid catabolic process GO:0006706 34 17 0,000 0,04173407 0,06289718 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,04173407 0,0628584 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04173407 0,06281967 ! gas transport GO:0015669 26 17 0,000 0,04173407 0,06278099 ! organic cation transport GO:0015695 32 17 0,000 0,04173407 0,06274236 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,04173407 0,06270377 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04173407 0,06266523 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04173407 0,06262674 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04413466 0,06618844 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04413466 0,06614783 ! limbic system development GO:0021761 40 18 0,000 0,04413466 0,06610727 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04413466 0,06606677 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04413466 0,06602631 ! adult walking behavior GO:0007628 36 18 0,000 0,04413466 0,0659859 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04413466 0,06594554 ! heart looping GO:0001947 34 18 0,000 0,04413466 0,06590523 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04413466 0,06586497 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04413466 0,06582476 ! centrosome cycle GO:0007098 26 18 0,000 0,04413466 0,0657846 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04413466 0,06574449 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04413466 0,06570443 ! glycine metabolic process GO:0006544 30 18 0,000 0,04413466 0,06566441 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04413466 0,06562444 ! response to retinoic acid GO:0032526 31 18 0,000 0,04413466 0,06558453 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04413466 0,06554466 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04413466 0,06550484 ! DNA integration GO:0015074 32 18 0,000 0,04413466 0,06546507 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04413466 0,06542534 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04413466 0,06538567 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04413466 0,06534604 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04413466 0,06530646 ! neural crest cell migration GO:0001755 41 18 0,000 0,04413466 0,06526693 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04413466 0,06522744 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04413466 0,06518801 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04413466 0,06514862 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04413466 0,06510928 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,04413466 0,06506998 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04413466 0,06503074 ! detection of bacterium GO:0016045 22 18 0,000 0,04413466 0,06499154 ! nerve development GO:0021675 34 18 0,000 0,04413466 0,06495239 ! defense response to virus GO:0051607 43 18 0,000 0,04413466 0,06491328 ! microspike assembly GO:0030035 46 18 0,000 0,04413466 0,06487423 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04413466 0,06483522 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04413466 0,06479625 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,0465293 0,06827091 ! positive regulation of translation GO:0045727 31 19 0,000 0,0465293 0,06822993 ! negative regulation of defense response GO:0031348 27 19 0,000 0,0465293 0,068189 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,0465293 0,06814812 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,0465293 0,06810729 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,0465293 0,06806651 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,0465293 0,06802578 ! inositol metabolic process GO:0006020 33 19 0,000 0,0465293 0,06798509 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0465293 0,06794445 ! memory GO:0007613 34 19 0,000 0,0465293 0,06790387 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,0465293 0,06786333 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,0465293 0,06782283 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,0465293 0,06778239 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,0465293 0,067742 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,0465293 0,06770165 ! cerebral cortex development GO:0021987 40 19 0,000 0,0465293 0,06766135 ! response to vitamin A GO:0033189 32 19 0,000 0,0465293 0,0676211 ! heme metabolic process GO:0042168 40 19 0,000 0,0465293 0,0675809 ! neuromuscular junction development GO:0007528 43 19 0,000 0,0465293 0,06754074 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,0465293 0,06750064 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,0465293 0,06746058 ! response to fungus GO:0009620 26 19 0,000 0,0465293 0,06742056 ! protein export from nucleus GO:0006611 40 19 0,000 0,0465293 0,0673806 ! heart process GO:0003015 32 19 0,000 0,0465293 0,06734068 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,0465293 0,06730081 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,0465293 0,06726099 ! visual learning GO:0008542 38 19 0,000 0,0465293 0,06722121 ! cellular pigmentation GO:0033059 37 19 0,000 0,0465293 0,06718148 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,0465293 0,0671418 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,0465293 0,06710217 ! vitamin transport GO:0051180 31 19 0,000 0,0465293 0,06706258 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,0465293 0,06702304 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,0465293 0,06698354 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,0465293 0,06694409 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,0465293 0,06690469 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,0465293 0,06686534 ! cilium assembly GO:0042384 38 19 0,000 0,0465293 0,06682603 ! peptide hormone secretion GO:0030072 32 19 0,000 0,0465293 0,06678676 ! protein secretion GO:0009306 45 20 0,000 0,04891801 0,07017421 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04891801 0,07013303 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04891801 0,0700919 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04891801 0,07005081 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04891801 0,07000978 ! skin development GO:0043588 42 20 0,000 0,04891801 0,06996879 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04891801 0,06992785 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04891801 0,06988695 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04891801 0,06984611 ! response to vitamin GO:0033273 36 20 0,000 0,04891801 0,06980531 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04891801 0,06976456 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04891801 0,06972385 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04891801 0,0696832 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04891801 0,06964259 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04891801 0,06960203 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04891801 0,06956152 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04891801 0,06952105 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04891801 0,06948063 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04891801 0,06944026 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,04891801 0,06939993 ! body fluid secretion GO:0007589 33 20 0,000 0,04891801 0,06935966 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04891801 0,06931942 ! peptide secretion GO:0002790 38 20 0,000 0,04891801 0,06927924 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04891801 0,0692391 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04891801 0,06919901 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04891801 0,06915896 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04891801 0,06911896 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04891801 0,06907901 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04891801 0,0690391 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04891801 0,06899924 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04891801 0,06895943 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04891801 0,06891966 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04891801 0,06887994 ! regulation of glucose import GO:0046324 30 20 0,000 0,04891801 0,06884026 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04891801 0,06880063 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04891801 0,06876104 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04891801 0,0687215 ! negative regulation of translation GO:0017148 32 20 0,000 0,04891801 0,068682 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04891801 0,06864255 ! regulation of cell killing GO:0031341 46 21 0,000 0,0513008 0,0719448 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,0513008 0,07190353 ! hormone secretion GO:0046879 39 21 0,000 0,0513008 0,0718623 ! cAMP metabolic process GO:0046058 41 21 0,000 0,0513008 0,07182112 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,0513008 0,07177998 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,0513008 0,07173889 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,0513008 0,07169785 ! ovarian follicle development GO:0001541 39 21 0,000 0,0513008 0,07165686 ! smooth muscle contraction GO:0006939 48 21 0,000 0,0513008 0,07161591 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,0513008 0,07157501 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,0513008 0,07153416 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,0513008 0,07149335 ! plasma membrane fusion GO:0045026 33 21 0,000 0,0513008 0,07145259 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,0513008 0,07141188 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,0513008 0,07137121 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,0513008 0,07133059 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,0513008 0,07129002 ! diencephalon development GO:0021536 36 21 0,000 0,0513008 0,07124949 ! collagen fibril organization GO:0030199 62 21 0,000 0,0513008 0,071209 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,0513008 0,07116857 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,0513008 0,07112818 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,0513008 0,07108783 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,0513008 0,07104753 ! collagen catabolic process GO:0030574 29 21 0,000 0,0513008 0,07100728 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,0513008 0,07096707 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,0513008 0,07092691 ! sperm-egg recognition GO:0035036 23 21 0,000 0,0513008 0,07088679 ! actin filament-based movement GO:0030048 47 21 0,000 0,0513008 0,07084672 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,0513008 0,07080669 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,05367769 0,0740455 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,05367769 0,07400372 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,05367769 0,07396198 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,05367769 0,07392029 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,05367769 0,07387864 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,05367769 0,07383704 ! microtubule-based transport GO:0010970 59 22 0,000 0,05367769 0,07379549 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,05367769 0,07375399 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,05367769 0,07371253 ! cellular response to starvation GO:0009267 37 22 0,000 0,05367769 0,07367112 ! vacuolar transport GO:0007034 41 22 0,000 0,05367769 0,07362975 ! fucose metabolic process GO:0006004 44 22 0,000 0,05367769 0,07358843 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,05367769 0,07354716 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,05367769 0,07350593 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,05367769 0,07346475 ! ureteric bud development GO:0001657 50 22 0,000 0,05367769 0,07342362 ! cell aging GO:0007569 48 22 0,000 0,05367769 0,07338253 ! stem cell differentiation GO:0048863 57 22 0,000 0,05367769 0,07334149 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,05367769 0,0733005 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,05367769 0,07325955 ! cytolysis GO:0019835 27 22 0,000 0,05367769 0,07321864 ! renal system process GO:0003014 42 22 0,000 0,05367769 0,07317778 ! vasodilation GO:0042311 40 22 0,000 0,05367769 0,07313697 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,05367769 0,0730962 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,05367769 0,07305548 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,05367769 0,0730148 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,05367769 0,07297417 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,05367769 0,07293359 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,05367769 0,07289304 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,05367769 0,07285255 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,05367769 0,0728121 ! sarcomere organization GO:0045214 32 22 0,000 0,05367769 0,07277169 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,05367769 0,07273133 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,05367769 0,07269101 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,05367769 0,07265074 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,05367769 0,07261051 ! gut development GO:0048565 44 22 0,000 0,05367769 0,07257033 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,05367769 0,07253019 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,05367769 0,0724901 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,05367769 0,07245005 ! protein stabilization GO:0050821 41 22 0,000 0,05367769 0,07241004 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,05604869 0,07556675 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05604869 0,07552506 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,05604869 0,07548343 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05604869 0,07544184 ! gluconeogenesis GO:0006094 38 23 0,000 0,05604869 0,0754003 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05604869 0,0753588 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05604869 0,07531735 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05604869 0,07527594 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,05604869 0,07523458 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05604869 0,07519327 ! regeneration GO:0031099 42 23 0,000 0,05604869 0,075152 ! axis specification GO:0009798 43 23 0,000 0,05604869 0,07511077 ! visual behavior GO:0007632 46 23 0,000 0,05604869 0,0750696 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,05604869 0,07502846 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05604869 0,07498737 ! response to ethanol GO:0045471 47 23 0,000 0,05604869 0,07494633 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05604869 0,07490533 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,05604869 0,07486438 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05604869 0,07482347 ! peroxisome organization GO:0007031 43 23 0,000 0,05604869 0,0747826 ! lysosome organization GO:0007040 47 23 0,000 0,05604869 0,07474178 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05604869 0,07470101 ! vesicle targeting GO:0006903 49 23 0,000 0,05604869 0,07466027 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,05604869 0,07461959 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05604869 0,07457894 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05604869 0,07453835 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05604869 0,07449779 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05604869 0,07445728 ! DNA modification GO:0006304 36 23 0,000 0,05604869 0,07441682 ! fatty acid transport GO:0015908 47 23 0,000 0,05604869 0,07437639 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05604869 0,07433602 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05604869 0,07429568 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05604869 0,07425539 ! hormone transport GO:0009914 41 23 0,000 0,05604869 0,07421514 ! cell-cell recognition GO:0009988 28 23 0,000 0,05604869 0,07417494 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05604869 0,07413478 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05604869 0,07409467 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05604869 0,07405459 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05841381 0,07713781 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05841381 0,07709614 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,05841381 0,07705451 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,05841381 0,07701292 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05841381 0,07697138 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05841381 0,07692989 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05841381 0,07688844 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05841381 0,07684704 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05841381 0,07680568 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05841381 0,07676436 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05841381 0,07672309 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05841381 0,07668186 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05841381 0,07664068 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05841381 0,07659954 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05841381 0,07655845 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,05841381 0,0765174 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05841381 0,07647639 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05841381 0,07643543 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05841381 0,07639451 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05841381 0,07635364 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05841381 0,07631281 ! pallium development GO:0021543 56 24 0,000 0,05841381 0,07627202 ! oogenesis GO:0048477 44 24 0,000 0,05841381 0,07623128 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05841381 0,07619057 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05841381 0,07614992 ! platelet activation GO:0030168 41 24 0,000 0,05841381 0,07610931 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05841381 0,07606874 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05841381 0,07602821 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05841381 0,07598772 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05841381 0,07594728 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05841381 0,07590689 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05841381 0,07586653 ! regulation of amine transport GO:0051952 41 24 0,000 0,05841381 0,07582622 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,06077308 0,07884686 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,06077308 0,07880501 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06077308 0,0787632 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06077308 0,07872144 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,06077308 0,07867972 ! phototransduction GO:0007602 37 25 0,000 0,06077308 0,07863805 ! keratinization GO:0031424 37 25 0,000 0,06077308 0,07859642 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,06077308 0,07855483 ! vacuole organization GO:0007033 49 25 0,000 0,06077308 0,07851329 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06077308 0,0784718 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,06077308 0,07843034 ! receptor metabolic process GO:0043112 53 25 0,000 0,06077308 0,07838893 ! chromosome condensation GO:0030261 48 25 0,000 0,06077308 0,07834757 ! regulation of behavior GO:0050795 48 25 0,000 0,06077308 0,07830624 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,06077308 0,07826496 ! interaction with host GO:0051701 66 25 0,000 0,06077308 0,07822373 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,06077308 0,07818254 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06077308 0,07814139 ! immunoglobulin production GO:0002377 62 25 0,000 0,06077308 0,07810028 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,06077308 0,07805922 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,06077308 0,0780182 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06077308 0,07797723 ! liver development GO:0001889 55 25 0,000 0,06077308 0,07793629 ! protein tetramerization GO:0051262 57 25 0,000 0,06077308 0,0778954 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,0631265 0,08086945 ! myelination GO:0042552 50 26 0,000 0,0631265 0,08082707 ! initiation of viral infection GO:0019059 60 26 0,000 0,0631265 0,08078473 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,0631265 0,08074243 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,0631265 0,08070018 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,0631265 0,08065797 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,0631265 0,08061581 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,0631265 0,08057369 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,0631265 0,08053162 ! digestive system process GO:0022600 49 26 0,000 0,0631265 0,08048959 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,0631265 0,0804476 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,0631265 0,08040566 ! neural crest cell development GO:0014032 59 26 0,000 0,0631265 0,08036376 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,0631265 0,0803219 ! negative regulation of cell development GO:0010721 83 26 0,000 0,0631265 0,08028009 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,0631265 0,08023832 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,0631265 0,08019659 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,0631265 0,08015491 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,0631265 0,08011327 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,0631265 0,08007168 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,0631265 0,08003012 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,0631265 0,07998861 ! blastocyst development GO:0001824 50 26 0,000 0,0631265 0,07994715 ! telomere organization GO:0032200 46 26 0,000 0,0631265 0,07990572 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,0631265 0,07986434 ! neural tube closure GO:0001843 58 26 0,000 0,0631265 0,07982301 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,0631265 0,07978171 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,0631265 0,07974046 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,0631265 0,07969925 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,06547409 0,08262046 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,06547409 0,08257781 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,06547409 0,0825352 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,06547409 0,08249263 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,06547409 0,08245011 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,06547409 0,08240763 ! iron ion transport GO:0006826 65 27 0,000 0,06547409 0,0823652 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,06547409 0,08232281 ! superoxide metabolic process GO:0006801 41 27 0,000 0,06547409 0,08228046 ! tube lumen formation GO:0035148 59 27 0,000 0,06547409 0,08223816 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,06547409 0,0821959 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,06547409 0,08215368 ! response to starvation GO:0042594 47 27 0,000 0,06547409 0,0821115 ! response to toxin GO:0009636 49 27 0,000 0,06547409 0,08206937 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,06547409 0,08202729 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,06547409 0,08198524 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,06547409 0,08194324 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,06547409 0,08190129 ! leukocyte proliferation GO:0070661 59 27 0,000 0,06547409 0,08185937 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,06547409 0,0818175 ! neuron fate commitment GO:0048663 52 28 0,000 0,06781587 0,08470049 ! circadian rhythm GO:0007623 56 28 0,000 0,06781587 0,08465721 ! dendrite development GO:0016358 67 28 0,000 0,06781587 0,08461398 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,06781587 0,08457078 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,06781587 0,08452764 ! sperm motility GO:0030317 37 28 0,000 0,06781587 0,08448453 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,06781587 0,08444147 ! base-excision repair GO:0006284 41 28 0,000 0,06781587 0,08439845 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,06781587 0,08435548 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,06781587 0,08431255 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,06781587 0,08426967 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,06781587 0,08422683 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,06781587 0,08418403 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,06781587 0,08414127 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,06781587 0,08409856 ! glutathione metabolic process GO:0006749 42 28 0,000 0,06781587 0,08405589 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,06781587 0,08401327 ! lipid oxidation GO:0034440 48 28 0,000 0,06781587 0,08397069 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,06781587 0,08392815 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,06781587 0,08388565 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,07015184 0,08673125 ! translational initiation GO:0006413 66 29 0,000 0,07015184 0,08668738 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,07015184 0,08664355 ! catechol metabolic process GO:0009712 55 29 0,000 0,07015184 0,08659977 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,07015184 0,08655603 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,07015184 0,08651234 ! primary neural tube formation GO:0014020 61 29 0,000 0,07015184 0,08646869 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,07015184 0,08642509 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,07015184 0,08638153 ! synaptogenesis GO:0007416 46 29 0,000 0,07015184 0,08633801 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,07015184 0,08629454 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,07015184 0,08625111 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,07015184 0,08620772 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,07015184 0,08616438 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,07248202 0,0889817 ! phenol metabolic process GO:0018958 56 30 0,000 0,07248202 0,08893701 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,07248202 0,08889236 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,07248202 0,08884776 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,07248202 0,0888032 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,07248202 0,08875869 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,07248202 0,08871422 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,07248202 0,0886698 ! acute-phase response GO:0006953 50 30 0,000 0,07248202 0,08862542 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,07248202 0,08858108 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,07248202 0,08853679 ! myofibril assembly GO:0030239 50 30 0,000 0,07248202 0,08849255 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,07248202 0,08844834 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,07248202 0,08840419 ! cell fate determination GO:0001709 64 30 0,000 0,07248202 0,08836007 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,07248202 0,088316 ! phospholipid transport GO:0015914 65 30 0,000 0,07248202 0,08827198 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,07248202 0,088228 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,07248202 0,08818406 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,07248202 0,08814016 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,07248202 0,08809631 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,07480643 0,09087624 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,07480643 0,09083107 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,07480643 0,09078595 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,07480643 0,09074087 ! cell junction assembly GO:0034329 85 31 0,000 0,07480643 0,09069584 ! regulation of innate immune response GO:0045088 57 31 0,000 0,07480643 0,09065085 ! ovulation cycle process GO:0022602 55 31 0,000 0,07480643 0,09060591 ! peptide transport GO:0015833 60 31 0,000 0,07480643 0,09056101 ! male gonad development GO:0008584 56 31 0,000 0,07480643 0,09051616 ! iron ion homeostasis GO:0055072 60 31 0,000 0,07480643 0,09047135 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,07480643 0,09042658 ! detection of light stimulus GO:0009583 44 31 0,000 0,07480643 0,09038186 ! natural killer cell activation GO:0030101 50 31 0,000 0,07480643 0,09033718 ! ensheathment of neurons GO:0007272 64 31 0,000 0,07480643 0,09029255 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,07480643 0,09024796 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,07480643 0,09020342 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,07480643 0,09015891 ! eye morphogenesis GO:0048592 65 31 0,000 0,07480643 0,09011446 ! response to heat GO:0009408 54 31 0,000 0,07480643 0,09007004 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,07480643 0,09002568 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,07712509 0,09277035 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,07712509 0,0927247 ! collagen metabolic process GO:0032963 49 32 0,000 0,07712509 0,09267909 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,07712509 0,09263352 ! spindle organization GO:0007051 50 32 0,000 0,07712509 0,092588 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,07712509 0,09254253 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,07712509 0,0924971 ! metanephros development GO:0001656 81 32 0,000 0,07712509 0,09245171 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,07712509 0,09240637 ! muscle cell development GO:0055001 52 32 0,000 0,07712509 0,09236107 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,07712509 0,09231582 ! ovulation cycle GO:0042698 57 32 0,000 0,07712509 0,09227061 ! peripheral nervous system development GO:0007422 68 32 0,000 0,07712509 0,09222544 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,07712509 0,09218032 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,07712509 0,09213525 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,07712509 0,09209022 ! gene silencing GO:0016458 71 32 0,000 0,07712509 0,09204523 ! regulation of pH GO:0006885 56 33 0,000 0,07943799 0,09475928 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,07943799 0,09471304 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,07943799 0,09466683 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,07943799 0,09462068 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,07943799 0,09457457 ! response to ionizing radiation GO:0010212 74 33 0,000 0,07943799 0,0945285 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,07943799 0,09448248 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,07943799 0,0944365 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,07943799 0,09439057 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,07943799 0,09434468 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,07943799 0,09429884 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,07943799 0,09425304 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,07943799 0,09420729 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,08174516 0,09689638 ! glial cell differentiation GO:0010001 67 34 0,000 0,08174516 0,09684939 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,08174516 0,09680244 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,08174516 0,09675554 ! spliceosome assembly GO:0000245 75 34 0,000 0,08174516 0,09670868 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,08174516 0,09666187 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,08174516 0,09661511 ! cell fate specification GO:0001708 56 34 0,000 0,08174516 0,09656839 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,08174516 0,09652172 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,08174516 0,09647509 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,08404662 0,09914335 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,08404662 0,09909551 ! negative regulation of secretion GO:0051048 68 35 0,000 0,08404662 0,0990477 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,08404662 0,09899995 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,08404662 0,09895224 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,08404662 0,09890457 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,08404662 0,09885695 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,08404662 0,09880938 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,08404662 0,09876185 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,08404662 0,09871437 ! ceramide metabolic process GO:0006672 72 35 0,000 0,08404662 0,09866693 ! telencephalon development GO:0021537 81 35 0,000 0,08404662 0,09861954 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,08404662 0,0985722 ! placenta development GO:0001890 53 35 0,000 0,08404662 0,0985249 ! vesicle localization GO:0051648 70 35 0,000 0,08404662 0,09847764 ! regulation of muscle development GO:0048634 82 36 0,000 0,08634237 0,10111908 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,08634237 0,10107063 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,08634237 0,10102223 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,08634237 0,10097387 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,08634237 0,10092555 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,08634237 0,10087729 ! positive regulation of cell development GO:0010720 85 36 0,000 0,08634237 0,10082907 ! protein targeting to membrane GO:0006612 75 36 0,000 0,08634237 0,10078089 ! regulation of proteolysis GO:0030162 77 36 0,000 0,08634237 0,10073276 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,08634237 0,10068468 ! aerobic respiration GO:0009060 56 36 0,000 0,08634237 0,10063665 ! cytokine production GO:0001816 68 36 0,000 0,08634237 0,10058865 ! embryonic organ development GO:0048568 67 36 0,000 0,08634237 0,10054071 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,08634237 0,10049281 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,08634237 0,10044496 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,08863243 0,10305999 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,08863243 0,10301096 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,08863243 0,10296197 ! sister chromatid segregation GO:0000819 65 37 0,000 0,08863243 0,10291304 ! actomyosin structure organization GO:0031032 68 37 0,000 0,08863243 0,10286415 ! cell junction organization GO:0034330 96 37 0,000 0,08863243 0,1028153 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,08863243 0,10276651 ! female gonad development GO:0008585 71 37 0,000 0,08863243 0,10271776 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,08863243 0,10266905 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,08863243 0,10262039 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,09091682 0,10521544 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,09091682 0,10516562 ! meiosis I GO:0007127 74 38 0,000 0,09091682 0,10511585 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,09091682 0,10506612 ! organic anion transport GO:0015711 82 38 0,000 0,09091682 0,10501645 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,09091682 0,10496682 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,09091682 0,10491724 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,09091682 0,1048677 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,09091682 0,10481821 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,09091682 0,10476877 ! regulation of protein stability GO:0031647 77 38 0,000 0,09091682 0,10471937 ! spermatid development GO:0007286 69 38 0,000 0,09091682 0,10467002 ! pigment metabolic process GO:0042440 87 38 0,000 0,09091682 0,10462072 ! neural tube formation GO:0001841 79 38 0,000 0,09091682 0,10457146 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,09319554 0,10714198 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,09319554 0,10709159 ! negative regulation of binding GO:0051100 71 39 0,000 0,09319554 0,10704124 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,09319554 0,10699094 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,09319554 0,10694068 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,09319554 0,10689048 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,09319554 0,10684032 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,09319554 0,1067902 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,09319554 0,10674014 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,09546862 0,10929233 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,09546862 0,10924114 ! learning GO:0007612 82 40 0,000 0,09546862 0,10919 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,09546862 0,1091389 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,09546862 0,10908786 ! mismatch repair GO:0006298 58 40 0,000 0,09546862 0,10903686 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,09546862 0,10898591 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,09546862 0,108935 ! RNA export from nucleus GO:0006405 61 41 0,000 0,09773606 0,11147022 ! mRNA catabolic process GO:0006402 79 41 0,000 0,09773606 0,1114182 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,09773606 0,11136623 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,09773606 0,11131431 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,09773606 0,11126244 ! gliogenesis GO:0042063 91 41 0,000 0,09773606 0,11121062 ! feeding behavior GO:0007631 69 41 0,000 0,09773606 0,11115885 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,09773606 0,11110712 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,09773606 0,11105544 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,09773606 0,11100381 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,09773606 0,11095223 ! spermatid differentiation GO:0048515 73 41 0,000 0,09773606 0,1109007 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,09773606 0,11084921 ! RNA modification GO:0009451 64 41 0,000 0,09773606 0,11079777 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,09999789 0,11330929 ! ear morphogenesis GO:0042471 64 42 0,000 0,09999789 0,11325676 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,09999789 0,11320428 ! T cell differentiation GO:0030217 93 42 0,000 0,09999789 0,11315185 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,09999789 0,11309946 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,09999789 0,11304712 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,09999789 0,11299484 ! regulation of protein secretion GO:0050708 77 42 0,000 0,09999789 0,1129426 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,09999789 0,1128904 ! cytokinesis GO:0000910 84 42 0,000 0,09999789 0,11283826 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,09999789 0,11278617 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,1022541 0,1152777 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,1022541 0,11522453 ! regulation of tube size GO:0035150 76 43 0,000 0,1022541 0,1151714 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,1022541 0,11511833 ! glucose transport GO:0015758 66 43 0,000 0,1022541 0,1150653 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,1022541 0,11501233 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,1022541 0,1149594 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,1022541 0,11490652 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,1022541 0,11485369 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,1022541 0,11480091 ! ion transmembrane transport GO:0034220 79 43 0,000 0,1022541 0,11474817 ! neuron migration GO:0001764 85 43 0,000 0,1022541 0,11469549 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,1022541 0,11464285 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,10450473 0,11711241 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,10450473 0,11705871 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,10450473 0,11700506 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,10450473 0,11695146 ! hexose transport GO:0008645 68 44 0,000 0,10450473 0,11689791 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,10450473 0,11684441 ! phagocytosis GO:0006909 105 44 0,000 0,10450473 0,11679096 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,10450473 0,11673756 ! double-strand break repair GO:0006302 85 44 0,000 0,10450473 0,11668421 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,10674977 0,11913645 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,10674977 0,11908205 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,10674977 0,1190277 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,10674977 0,1189734 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,10674977 0,11891915 ! female gamete generation GO:0007292 71 45 0,000 0,10674977 0,11886494 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,10674977 0,11881079 ! polyol metabolic process GO:0019751 77 45 0,000 0,10674977 0,11875669 ! developmental growth GO:0048589 88 45 0,000 0,10674977 0,11870263 ! maintenance of location in cell GO:0051651 101 45 0,000 0,10674977 0,11864863 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,10898925 0,12108264 ! glycolysis GO:0006096 71 46 0,000 0,10898925 0,12102761 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,10898925 0,12097262 ! leukocyte migration GO:0050900 75 46 0,000 0,10898925 0,12091768 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,10898925 0,12086279 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,10898925 0,12080796 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,10898925 0,12075317 ! cell growth GO:0016049 90 46 0,000 0,10898925 0,12069843 ! neural tube development GO:0021915 91 47 0,000 0,11122318 0,12311655 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,11122318 0,12306079 ! positive regulation of defense response GO:0031349 88 48 0,000 0,11345157 0,12546952 ! cellular component disassembly GO:0022411 89 48 0,000 0,11345157 0,12541275 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,11345157 0,12535603 ! endosome transport GO:0016197 127 48 0,000 0,11345157 0,12529936 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,11345157 0,12524274 ! male sex differentiation GO:0046661 93 48 0,000 0,11345157 0,12518617 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,11345157 0,12512965 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,11345157 0,12507318 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,11345157 0,12501677 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,11345157 0,1249604 ! response to calcium ion GO:0051592 94 49 0,000 0,11567443 0,12735135 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,11567443 0,12729398 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,11567443 0,12723667 ! JNK cascade GO:0007254 106 49 0,000 0,11567443 0,1271794 ! regulation of ion transport GO:0043269 86 50 0,000 0,11789178 0,12955899 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,11789178 0,12950073 ! endocrine system development GO:0035270 109 50 0,000 0,11789178 0,12944253 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,11789178 0,12938438 ! activation of caspase activity GO:0006919 95 50 0,000 0,11789178 0,12932628 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,11789178 0,12926824 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,11789178 0,12921024 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,11789178 0,1291523 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,12010364 0,13151645 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,12010364 0,13145752 ! peptide metabolic process GO:0006518 80 51 0,000 0,12010364 0,13139865 ! response to temperature stimulus GO:0009266 84 51 0,000 0,12010364 0,13133984 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,12010364 0,13128107 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,12010364 0,13122236 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,12231001 0,13357325 ! Notch signaling pathway GO:0007219 111 52 0,000 0,12231001 0,13351357 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,12231001 0,13345394 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,12231001 0,13339436 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,12231001 0,13333483 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,12231001 0,13327536 ! excretion GO:0007588 87 52 0,000 0,12231001 0,13321594 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,12231001 0,13315658 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,12231001 0,13309727 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,12231001 0,13303801 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,12231001 0,1329788 ! amino acid activation GO:0043038 98 52 0,000 0,12231001 0,13291965 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,12451092 0,1352513 ! positive regulation of growth GO:0045927 96 53 0,000 0,12451092 0,13519119 ! inner ear development GO:0048839 89 53 0,000 0,12451092 0,13513113 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,12451092 0,13507112 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,12451092 0,13501117 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,12451092 0,13495127 ! cartilage development GO:0051216 99 53 0,000 0,12451092 0,13489143 ! synapse organization GO:0050808 102 53 0,000 0,12451092 0,13483163 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,12670636 0,13714827 ! regulation of translational initiation GO:0006446 87 54 0,000 0,12670636 0,13708753 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,12670636 0,13702684 ! neuromuscular process GO:0050905 107 54 0,000 0,12670636 0,13696621 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,12670636 0,13690563 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,12670636 0,13684511 ! regulation of cell shape GO:0008360 142 54 0,000 0,12670636 0,13678464 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,12670636 0,13672422 ! RNA catabolic process GO:0006401 103 55 0,000 0,12889636 0,13902596 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,12889636 0,13896461 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,12889636 0,13890331 ! cell recognition GO:0008037 98 55 0,000 0,12889636 0,13884207 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,12889636 0,13878088 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,12889636 0,13871974 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,13108093 0,14100868 ! glucose catabolic process GO:0006007 88 56 0,000 0,13108093 0,14094662 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,13108093 0,14088461 ! regulation of DNA replication GO:0006275 105 56 0,000 0,13108093 0,14082265 ! RNA elongation GO:0006354 90 56 0,000 0,13108093 0,14076075 ! chloride transport GO:0006821 102 57 0,000 0,13326009 0,14303796 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,13326009 0,14297514 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 0,000 0,13326009 0,14291237 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,13326009 0,14284967 ! regulation of actin filament length GO:0030832 118 58 0,000 0,13543383 0,14511617 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,13543383 0,14505255 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,13543383 0,14498898 ! aging GO:0007568 112 58 0,000 0,13543383 0,14492547 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,13543383 0,14486202 ! maintenance of location GO:0051235 124 58 0,000 0,13543383 0,14479863 ! nuclear export GO:0051168 110 59 0,000 0,13760219 0,14705256 ! establishment of organelle localization GO:0051656 122 59 0,000 0,13760219 0,14698826 ! DNA catabolic process GO:0006308 94 60 0,000 0,13976518 0,14923353 ! regulation of endocytosis GO:0030100 104 60 0,000 0,13976518 0,14916834 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,13976518 0,1491032 ! kidney development GO:0001822 133 60 0,000 0,13976518 0,14903812 ! regulation of cellular component size GO:0032535 125 61 0,000 0,14192279 0,15127285 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,14192279 0,15120688 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,14192279 0,15114097 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,14192279 0,15107511 ! regulation of heart contraction GO:0008016 123 61 0,000 0,14192279 0,15100931 ! camera-type eye development GO:0043010 126 61 0,000 0,14192279 0,15094357 ! proton transport GO:0015992 117 61 0,000 0,14192279 0,15087789 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,14192279 0,15081226 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,14407506 0,15303277 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,14407506 0,15296626 ! tRNA processing GO:0008033 102 62 0,000 0,14407506 0,15289981 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,14407506 0,15283342 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,14622199 0,15504354 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,14622199 0,15497628 ! hydrogen transport GO:0006818 121 64 0,000 0,14836359 0,15717791 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,14836359 0,15710978 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,14836359 0,1570417 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,15049988 0,15923396 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,15049988 0,15916503 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,15049988 0,15909616 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,15049988 0,15902734 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,15049988 0,15895859 ! ear development GO:0043583 114 66 0,000 0,15263088 0,16113969 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,15263088 0,16107008 ! gonad development GO:0008406 115 66 0,000 0,15263088 0,16100053 ! activation of MAPK activity GO:0000187 124 67 0,000 0,15475658 0,16317235 ! chromosome segregation GO:0007059 127 67 0,000 0,15475658 0,16310196 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,15475658 0,16303162 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,15475658 0,16296135 ! secondary metabolic process GO:0019748 125 67 0,000 0,15475658 0,16289114 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,15475658 0,16282099 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,15687702 0,16498087 ! hexose catabolic process GO:0019320 113 68 0,000 0,15687702 0,16490988 ! extracellular matrix organization GO:0030198 146 68 0,000 0,15687702 0,16483895 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,15687702 0,16476808 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,15687702 0,16469727 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,15687702 0,16462653 ! adaptive immune response GO:0002250 126 68 0,000 0,15687702 0,16455584 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,15687702 0,16448522 ! cell projection assembly GO:0030031 138 68 0,000 0,15687702 0,16441465 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,15899219 0,16656 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,15899219 0,16648861 ! urogenital system development GO:0001655 149 69 0,000 0,15899219 0,16641728 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,15899219 0,16634601 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,15899219 0,1662748 ! single fertilization GO:0007338 83 69 0,000 0,15899219 0,16620365 ! cell redox homeostasis GO:0045454 114 70 0,000 0,16110212 0,16833725 ! germ cell development GO:0007281 133 70 0,000 0,16110212 0,16826528 ! activation of immune response GO:0002253 120 70 0,000 0,16110212 0,16819337 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,16110212 0,16812152 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,16320682 0,1702452 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,16320682 0,17017254 ! carbohydrate transport GO:0008643 114 72 0,000 0,16530629 0,17228808 ! actin filament organization GO:0007015 167 72 0,000 0,16530629 0,17221461 ! B cell activation GO:0042113 179 72 0,000 0,16530629 0,1721412 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,16530629 0,17206786 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,16530629 0,17199458 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,16530629 0,17192136 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,16530629 0,1718482 ! humoral immune response GO:0006959 115 73 0,000 0,16740055 0,17395132 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,16740055 0,17387736 ! regulation of immune effector process GO:0002697 156 73 0,000 0,16740055 0,17380346 ! acute inflammatory response GO:0002526 118 74 0,000 0,16948962 0,17589768 ! amino acid transport GO:0006865 148 74 0,000 0,16948962 0,17582299 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,16948962 0,17574836 ! organelle localization GO:0051640 155 74 0,000 0,16948962 0,1756738 ! transition metal ion transport GO:0000041 143 75 0,000 0,17157351 0,1777583 ! reproductive structure development GO:0048608 131 75 0,000 0,17157351 0,17768295 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,17157351 0,17760766 ! eye development GO:0001654 155 75 0,000 0,17157351 0,17753243 ! axon guidance GO:0007411 162 75 0,000 0,17157351 0,17745727 ! rhythmic process GO:0048511 142 75 0,000 0,17157351 0,17738217 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,17365222 0,17945532 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,17365222 0,17937944 ! learning or memory GO:0007611 161 76 0,000 0,17365222 0,17930363 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,17365222 0,17922787 ! regulation of blood pressure GO:0008217 134 76 0,000 0,17365222 0,17915219 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,17365222 0,17907656 ! amine catabolic process GO:0009310 136 77 0,000 0,17572578 0,18113843 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,17572578 0,18106203 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,17572578 0,1809857 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,17572578 0,18090943 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,17572578 0,18083323 ! regulation of catabolic process GO:0009894 173 77 0,000 0,17572578 0,18075709 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,17779419 0,18280775 ! antigen processing and presentation GO:0019882 117 78 0,000 0,17779419 0,18273084 ! fertilization GO:0009566 99 78 0,000 0,17779419 0,182654 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,17985747 0,18469601 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,17985747 0,18461841 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,17985747 0,18454087 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,17985747 0,1844634 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,17985747 0,18438599 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,18191564 0,18641774 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,18191564 0,18633958 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,18191564 0,18626148 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,18396869 0,18828467 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,18601665 0,19030095 ! protein import into nucleus GO:0006606 174 82 0,000 0,18601665 0,19022129 ! exocytosis GO:0006887 153 83 0,000 0,18805953 0,19222988 ! response to drug GO:0042493 149 83 0,000 0,18805953 0,19214949 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,18805953 0,19206916 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,18805953 0,19198889 ! nuclear import GO:0051170 177 83 0,000 0,18805953 0,1919087 ! inorganic anion transport GO:0015698 156 83 0,000 0,18805953 0,19182857 ! response to metal ion GO:0010038 158 84 0,000 0,19009733 0,19382629 ! T cell activation GO:0042110 189 84 0,000 0,19009733 0,19374543 ! response to nutrient GO:0007584 135 84 0,000 0,19009733 0,19366463 ! digestion GO:0007586 130 84 0,000 0,19009733 0,1935839 ! regulation of ligase activity GO:0051340 147 84 0,000 0,19009733 0,19350324 ! negative regulation of transport GO:0051051 164 85 0,000 0,19213008 0,19549096 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,19213008 0,19540957 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,19213008 0,19532826 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,19213008 0,195247 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,19618046 0,1992802 ! alcohol catabolic process GO:0046164 142 87 0,000 0,19618046 0,19919737 ! nucleosome assembly GO:0006334 126 87 0,000 0,19618046 0,19911461 ! cellular respiration GO:0045333 143 88 0,000 0,19819812 0,2010789 ! amine biosynthetic process GO:0009309 146 88 0,000 0,19819812 0,20099543 ! sensory perception of smell GO:0007608 117 88 0,000 0,19819812 0,20091203 ! chromatin assembly GO:0031497 128 88 0,000 0,19819812 0,2008287 ! tube morphogenesis GO:0035239 194 89 0,000 0,20021076 0,20278395 ! cellular defense response GO:0006968 123 89 0,000 0,20021076 0,20269992 ! protein localization in nucleus GO:0034504 192 89 0,000 0,20021076 0,20261595 ! regulation of neurological system process GO:0031644 175 89 0,000 0,20021076 0,20253205 ! response to inorganic substance GO:0010035 173 90 0,000 0,20221841 0,2044783 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,20221841 0,2043937 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,20221841 0,20430917 ! defense response to bacterium GO:0042742 112 91 0,000 0,20422108 0,20624725 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,20621878 0,20817871 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,20621878 0,20809272 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,20821151 0,21001682 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,20821151 0,20993014 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,20821151 0,20984354 ! vitamin metabolic process GO:0006766 153 93 0,000 0,20821151 0,209757 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,21019931 0,21167226 ! female pregnancy GO:0007565 166 94 0,000 0,21019931 0,21158504 ! sterol metabolic process GO:0016125 166 94 0,000 0,21019931 0,2114979 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,21019931 0,21141083 ! regulation of defense response GO:0031347 171 95 0,000 0,21218216 0,21331729 ! nucleosome organization GO:0034728 143 95 0,000 0,21218216 0,21322954 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,21218216 0,21314187 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,21218216 0,21305426 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,21218216 0,21296673 ! sex differentiation GO:0007548 171 96 0,000 0,2141601 0,2148637 ! regulation of T cell activation GO:0050863 175 96 0,000 0,2141601 0,2147755 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,21613312 0,21666525 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,21613312 0,21657638 ! transcription initiation GO:0006352 171 97 0,000 0,21613312 0,21648758 ! leukocyte differentiation GO:0002521 232 98 0,000 0,21810125 0,2183694 ! mRNA transport GO:0051028 185 100 0,000 0,22202285 0,22220476 ! positive regulation of immune response GO:0050778 175 100 0,000 0,22202285 0,22211377 ! hormone metabolic process GO:0042445 171 100 0,000 0,22202285 0,22202285