pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1245-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin receptor signaling pathway GO:0008286 64 26 4,000 4,169E-07 1,003E-03 ! gland morphogenesis GO:0022612 29 12 3,000 5,755E-07 6,923E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 1,153E-06 9,247E-04 ! response to peptide hormone stimulus GO:0043434 122 61 5,000 1,716E-06 1,032E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 2,000 2,047E-06 9,848E-04 ! positive regulation of cell motion GO:0051272 146 64 5,000 2,283E-06 9,155E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 2,62E-06 9,005E-04 ! positive regulation of microtubule polymerization GO:0031116 13 6 2,000 4,075E-06 1,226E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 5,427E-06 1,451E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 5,427E-06 1,306E-03 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 7,101E-06 1,553E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 7,101E-06 1,424E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 2,000 7,101E-06 1,314E-03 ! regulation of microtubule polymerization GO:0031113 15 7 2,000 7,101E-06 1,22E-03 ! protein oligomerization GO:0051259 139 78 5,000 7,302E-06 1,171E-03 ! regulation of peptidase activity GO:0052547 134 79 5,000 7,863E-06 1,182E-03 ! response to insulin stimulus GO:0032868 95 46 4,000 7,89E-06 1,117E-03 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 9,761E-06 1,305E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,131E-05 1,432E-03 ! gland development GO:0048732 206 88 5,000 1,467E-05 1,765E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 1,629E-05 1,866E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 2,000 1,689E-05 1,847E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,689E-05 1,767E-03 ! gas homeostasis GO:0033483 16 9 2,000 1,689E-05 1,693E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 2,21E-05 2,127E-03 ! positive regulation of cell migration GO:0030335 126 57 4,000 2,286E-05 2,116E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 2,403E-05 2,141E-03 ! cholesterol homeostasis GO:0042632 53 31 3,000 3,349E-05 2,878E-03 GO:0055092|sterol homeostasis, ! ear development GO:0043583 103 62 4,000 3,449E-05 2,862E-03 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 3,729E-05 2,991E-03 ! focal adhesion formation GO:0048041 35 12 2,000 4,366E-05 3,389E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 5,026E-05 3,779E-03 ! chromosome segregation GO:0007059 113 67 4,000 5,026E-05 3,664E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 5,399E-05 3,821E-03 ! lipid localization GO:0010876 28 13 2,000 5,652E-05 3,885E-03 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 25 13 2,000 5,652E-05 3,777E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 5,793E-05 3,767E-03 ! mitotic sister chromatid segregation GO:0000070 57 36 3,000 6,126E-05 3,879E-03 ! sister chromatid segregation GO:0000819 58 37 3,000 6,837E-05 4,218E-03 ! meiosis I GO:0007127 65 37 3,000 6,837E-05 4,112E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 7,109E-05 4,172E-03 ! lipid homeostasis GO:0055088 67 38 3,000 7,605E-05 4,357E-03 ! mammary gland development GO:0030879 86 39 3,000 8,436E-05 4,72E-03 ! regulation of vasodilation GO:0042312 26 15 2,000 8,913E-05 4,874E-03 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 2,000 1,092E-04 5,839E-03 ! response to hypoxia GO:0001666 171 81 4,000 1,247E-04 6,522E-03 ! positive regulation of protein complex assembly GO:0031334 32 17 2,000 1,32E-04 6,759E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 1,32E-04 6,618E-03 ! response to oxygen levels GO:0070482 176 83 4,000 1,4E-04 6,872E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,578E-04 7,591E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,578E-04 7,442E-03 ! pigmentation GO:0043473 100 46 3,000 1,62E-04 7,497E-03 ! mitochondrion organization GO:0007005 148 86 4,000 1,655E-04 7,512E-03 ! protein homooligomerization GO:0051260 76 47 3,000 1,763E-04 7,854E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 1,865E-04 8,159E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,185E-04 9,386E-03 ! response to alkaloid GO:0043279 38 20 2,000 2,185E-04 9,222E-03 ! cellular response to starvation GO:0009267 33 20 2,000 2,185E-04 9,063E-03 ! regulation of fatty acid metabolic process GO:0019217 38 20 2,000 2,185E-04 8,909E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,185E-04 8,761E-03 ! negative regulation of translation GO:0017148 29 20 2,000 2,185E-04 8,617E-03 ! regulation of membrane potential GO:0042391 164 93 4,000 2,388E-04 9,268E-03 ! vesicle organization GO:0016050 107 51 3,000 2,424E-04 9,259E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 2,538E-04 9,54E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,538E-04 9,393E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,538E-04 9,251E-03 ! regulation of vasoconstriction GO:0019229 39 21 2,000 2,538E-04 9,113E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 2,614E-04 9,25E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 2,637E-04 9,196E-03 ! forebrain development GO:0030900 188 95 4,000 2,637E-04 9,065E-03 ! keratinization GO:0031424 28 22 2,000 2,926E-04 9,914E-03 ! positive regulation of cytoskeleton organization GO:0051495 48 22 2,000 2,926E-04 9,776E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,926E-04 9,642E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 2,926E-04 9,512E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 2,926E-04 9,385E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 2,926E-04 9,262E-03 ! interphase GO:0051325 213 98 4,000 3,047E-04 9,521E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 3,35E-04 0,01033272 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 3,35E-04 0,01020193 ! neuron fate determination GO:0048664 7 5 1,000 3,472E-04 0,01044136 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,472E-04 0,01031245 ! Notch receptor processing GO:0007220 8 5 1,000 3,472E-04 0,01018669 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 1,000 3,472E-04 0,01006396 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,472E-04 9,944E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,472E-04 9,827E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,472E-04 9,713E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 3,472E-04 9,601E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,472E-04 9,492E-03 ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 3,472E-04 9,385E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 3,472E-04 9,281E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,472E-04 9,179E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,472E-04 9,079E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,472E-04 8,982E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 3,472E-04 8,886E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,472E-04 8,793E-03 ! positive regulation of organelle organization GO:0010638 100 56 3,000 3,482E-04 8,727E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,728E-04 9,246E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 3,812E-04 9,358E-03 ! membrane depolarization GO:0051899 39 24 2,000 3,812E-04 9,263E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 4,312E-04 0,01037586 ! vasculogenesis GO:0001570 46 25 2,000 4,312E-04 0,01027313 ! regulation of smooth muscle contraction GO:0006940 43 25 2,000 4,312E-04 0,01017241 ! response to starvation GO:0042594 42 25 2,000 4,312E-04 0,01007365 ! regulation of blood coagulation GO:0030193 40 25 2,000 4,312E-04 9,977E-03 ! cellular response to nutrient levels GO:0031669 41 25 2,000 4,312E-04 9,882E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 4,854E-04 0,0110171 ! regulation of cellular ketone metabolic process GO:0010565 44 26 2,000 4,854E-04 0,01091414 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 5,187E-04 0,01155611 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 5,187E-04 0,01145009 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 5,187E-04 0,011346 ! male sex determination GO:0030238 15 6 1,000 5,187E-04 0,01124379 ! 5S class rRNA transcription GO:0042791 11 6 1,000 5,187E-04 0,01114339 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! establishment of spindle localization GO:0051293 12 6 1,000 5,187E-04 0,01104478 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 14 6 1,000 5,187E-04 0,0109479 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 5,187E-04 0,0108527 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 5,187E-04 0,01075914 ! regulation of chromosome organization GO:0033044 42 27 2,000 5,437E-04 0,01118005 ! negative regulation of neuron differentiation GO:0045665 42 27 2,000 5,437E-04 0,01108531 ! regulation of mitosis GO:0007088 105 63 3,000 5,468E-04 0,01105449 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 148 66 3,000 6,524E-04 0,0130816 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 6,733E-04 0,01338742 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 6,733E-04 0,01327768 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 6,733E-04 0,01316973 ! regulation of coagulation GO:0050818 46 29 2,000 6,733E-04 0,01306353 ! tRNA transcription GO:0009304 14 7 1,000 7,234E-04 0,01392361 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,234E-04 0,0138131 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,234E-04 0,01370434 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 7,234E-04 0,01359727 ! vesicle fusion GO:0006906 17 7 1,000 7,234E-04 0,01349187 ! organ growth GO:0035265 15 7 1,000 7,234E-04 0,01338808 ! spindle checkpoint GO:0031577 15 7 1,000 7,234E-04 0,01328588 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 1,000 7,234E-04 0,01318523 ! B cell lineage commitment GO:0002326 21 7 1,000 7,234E-04 0,0130861 ! T cell lineage commitment GO:0002360 16 7 1,000 7,234E-04 0,01298844 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,234E-04 0,01289223 ! peptidyl-histidine modification GO:0018202 16 7 1,000 7,234E-04 0,01279743 ! negative regulation of nuclear division GO:0051784 14 7 1,000 7,234E-04 0,01270402 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 1,000 7,234E-04 0,01261196 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 7,234E-04 0,01252123 ! protein maturation by peptide bond cleavage GO:0051605 105 68 3,000 7,305E-04 0,01255376 ! cell junction assembly GO:0034329 78 30 2,000 7,448E-04 0,01270943 ! negative regulation of protein kinase cascade GO:0010741 68 30 2,000 7,448E-04 0,01261993 ! triglyceride metabolic process GO:0006641 43 31 2,000 8,21E-04 0,01381399 ! iron ion homeostasis GO:0055072 54 31 2,000 8,21E-04 0,01371806 ! cholesterol transport GO:0030301 56 32 2,000 9,02E-04 0,01496738 ! spindle organization GO:0007051 46 32 2,000 9,02E-04 0,01486486 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 9,02E-04 0,01476374 ! hindbrain development GO:0030902 61 32 2,000 9,02E-04 0,01466398 ! positive regulation of catabolic process GO:0009896 64 32 2,000 9,02E-04 0,01456557 ! regulation of caspase activity GO:0043281 122 72 3,000 9,059E-04 0,01453132 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 1,000 9,607E-04 0,01530814 ! signal peptide processing GO:0006465 12 8 1,000 9,607E-04 0,01520743 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 9,607E-04 0,01510803 ! negative regulation of endocytosis GO:0045806 11 8 1,000 9,607E-04 0,01500993 ! pigment granule organization GO:0048753 16 8 1,000 9,607E-04 0,01491309 ! ER overload response GO:0006983 12 8 1,000 9,607E-04 0,0148175 ! regulation of pigmentation during development GO:0048070 24 8 1,000 9,607E-04 0,01472312 ! melanin metabolic process GO:0006582 15 8 1,000 9,607E-04 0,01462993 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 9,607E-04 0,01453792 ! response to UV-B GO:0010224 16 8 1,000 9,607E-04 0,01444706 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 9,607E-04 0,01435732 ! DNA damage checkpoint GO:0000077 71 33 2,000 9,879E-04 0,01467231 ! sterol transport GO:0015918 57 33 2,000 9,879E-04 0,0145823 ! meiosis GO:0007126 121 74 3,000 1,004E-03 0,01472857 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,004E-03 0,01463931 ! cell-matrix adhesion GO:0007160 163 75 3,000 1,056E-03 0,01530031 ! meiotic cell cycle GO:0051321 122 75 3,000 1,056E-03 0,0152087 ! neutral lipid metabolic process GO:0006638 50 35 2,000 1,175E-03 0,01682502 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 2,000 1,175E-03 0,01672546 ! response to steroid hormone stimulus GO:0048545 137 78 3,000 1,222E-03 0,01729325 ! regulation of developmental growth GO:0048638 15 9 1,000 1,23E-03 0,01731201 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,23E-03 0,01721136 ! regulation of glycolysis GO:0006110 21 9 1,000 1,23E-03 0,01711187 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,23E-03 0,01701353 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 1,23E-03 0,01691631 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,23E-03 0,01682019 ! T cell selection GO:0045058 23 9 1,000 1,23E-03 0,01672516 ! behavioral fear response GO:0001662 22 9 1,000 1,23E-03 0,0166312 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 16 9 1,000 1,23E-03 0,01653829 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,23E-03 0,01644641 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,23E-03 0,01635555 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,23E-03 0,01626568 ! branched chain family amino acid catabolic process GO:0009083 17 9 1,000 1,23E-03 0,0161768 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,23E-03 0,01608888 ! cell junction organization GO:0034330 86 36 2,000 1,276E-03 0,01659551 ! positive regulation of cell development GO:0010720 80 36 2,000 1,276E-03 0,01650628 ! DNA integrity checkpoint GO:0031570 75 36 2,000 1,276E-03 0,01641802 ! tissue remodeling GO:0048771 76 37 2,000 1,383E-03 0,01769443 ! glycerol ether metabolic process GO:0006662 53 37 2,000 1,383E-03 0,01760081 ! glycogen metabolic process GO:0005977 61 37 2,000 1,383E-03 0,01750817 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,406E-03 0,01770668 ! regulation of neuron differentiation GO:0045664 167 81 3,000 1,406E-03 0,01761446 ! response to drug GO:0042493 143 82 3,000 1,471E-03 0,01833733 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,495E-03 0,01853609 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,495E-03 0,01844103 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 62 38 2,000 1,495E-03 0,01834694 GO:0006073|cellular glucan metabolic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,532E-03 0,01871061 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,532E-03 0,01861611 ! B cell proliferation GO:0042100 18 10 1,000 1,532E-03 0,01852256 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,532E-03 0,01842995 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 1,000 1,532E-03 0,01833826 ! response to dsRNA GO:0043331 20 10 1,000 1,532E-03 0,01824748 ! midbrain development GO:0030901 13 10 1,000 1,532E-03 0,01815759 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,532E-03 0,01806858 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,532E-03 0,01798044 ! response to nicotine GO:0035094 20 10 1,000 1,532E-03 0,01789316 ! ear morphogenesis GO:0042471 60 39 2,000 1,612E-03 0,01873794 ! organic ether metabolic process GO:0018904 55 39 2,000 1,612E-03 0,01864786 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 1,612E-03 0,01855863 ! keratinocyte differentiation GO:0030216 62 41 2,000 1,864E-03 0,02135767 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,865E-03 0,02126783 ! adult heart development GO:0007512 14 11 1,000 1,865E-03 0,02116751 ! negative regulation of ossification GO:0030279 26 11 1,000 1,865E-03 0,02106814 ! DNA methylation GO:0006306 19 11 1,000 1,865E-03 0,02096969 GO:0006305|DNA alkylation, ! oocyte differentiation GO:0009994 18 11 1,000 1,865E-03 0,02087215 ! thymus development GO:0048538 27 11 1,000 1,865E-03 0,02077552 ! sequestering of metal ion GO:0051238 14 11 1,000 1,865E-03 0,02067978 ! regulation of embryonic development GO:0045995 27 11 1,000 1,865E-03 0,02058492 ! response to reactive oxygen species GO:0000302 67 42 2,000 1,999E-03 0,02195967 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,999E-03 0,02185985 ! regulation of cell cycle process GO:0010564 149 90 3,000 2,071E-03 0,0225508 ! energy reserve metabolic process GO:0006112 74 43 2,000 2,139E-03 0,02318664 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 2,229E-03 0,02405383 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,229E-03 0,02394645 ! virus-host interaction GO:0019048 29 12 1,000 2,229E-03 0,02384002 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,229E-03 0,02373453 ! membrane protein proteolysis GO:0033619 25 12 1,000 2,229E-03 0,02362998 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 26 12 1,000 2,229E-03 0,02352634 ! histone methylation GO:0016571 26 12 1,000 2,229E-03 0,0234236 ! mRNA polyadenylation GO:0006378 23 12 1,000 2,229E-03 0,02332176 ! T cell homeostasis GO:0043029 25 12 1,000 2,229E-03 0,0232208 ! spleen development GO:0048536 22 12 1,000 2,229E-03 0,02312071 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,229E-03 0,02302148 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! male sex differentiation GO:0046661 76 44 2,000 2,286E-03 0,02350482 ! biopolymer methylation GO:0043414 84 44 2,000 2,286E-03 0,0234048 ! JAK-STAT cascade GO:0007259 71 44 2,000 2,286E-03 0,02330562 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 2,335E-03 0,0237 ! transcription initiation GO:0006352 153 94 3,000 2,427E-03 0,02453653 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 2,439E-03 0,02455001 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,439E-03 0,02444772 ! regulation of Rho protein signal transduction GO:0035023 213 95 3,000 2,522E-03 0,02518047 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,598E-03 0,02582484 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,598E-03 0,02571857 ! epidermal cell differentiation GO:0009913 68 46 2,000 2,598E-03 0,02561316 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,598E-03 0,02550862 ! organelle fusion GO:0048284 32 13 1,000 2,625E-03 0,02566892 ! endocrine pancreas development GO:0031018 22 13 1,000 2,625E-03 0,025565 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,625E-03 0,02546192 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,625E-03 0,02535966 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,625E-03 0,02525822 ! mRNA 3'-end processing GO:0031124 24 13 1,000 2,625E-03 0,02515759 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,72E-03 0,02596992 ! regulation of protein localization GO:0032880 176 97 3,000 2,72E-03 0,02586727 ! methylation GO:0032259 90 47 2,000 2,763E-03 0,02616852 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,934E-03 0,02768322 ! cellular component disassembly GO:0022411 86 48 2,000 2,934E-03 0,02757509 ! activation of caspase activity GO:0006919 84 48 2,000 2,934E-03 0,02746779 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,934E-03 0,02736133 ! rRNA transcription GO:0009303 25 14 1,000 3,05E-03 0,02833307 ! hair follicle morphogenesis GO:0031069 26 14 1,000 3,05E-03 0,02822409 ! RNA polyadenylation GO:0043631 30 14 1,000 3,05E-03 0,02811595 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,05E-03 0,02800864 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,05E-03 0,02790214 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 3,05E-03 0,02779645 ! response to gamma radiation GO:0010332 28 14 1,000 3,05E-03 0,02769156 ! male genitalia development GO:0030539 24 14 1,000 3,05E-03 0,02758746 ! regulation of RNA stability GO:0043487 32 14 1,000 3,05E-03 0,02748413 ! endocrine system development GO:0035270 104 49 2,000 3,112E-03 0,02793676 ! regulation of ossification GO:0030278 117 50 2,000 3,296E-03 0,02948132 ! inner ear development GO:0048839 79 50 2,000 3,296E-03 0,02937213 ! response to estrogen stimulus GO:0043627 93 51 2,000 3,487E-03 0,0309582 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,506E-03 0,03100822 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,506E-03 0,03089464 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 3,506E-03 0,03078189 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! glycoprotein catabolic process GO:0006516 26 15 1,000 3,506E-03 0,03066995 ! pituitary gland development GO:0021983 29 15 1,000 3,506E-03 0,03055883 ! muscle maintenance GO:0046716 26 15 1,000 3,506E-03 0,03044851 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,506E-03 0,03033898 ! membrane fusion GO:0006944 110 52 2,000 3,684E-03 0,03177353 ! positive regulation of growth GO:0045927 90 52 2,000 3,684E-03 0,03166005 ! regulation of protein polymerization GO:0032271 103 53 2,000 3,889E-03 0,03329562 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,991E-03 0,03404819 ! auditory receptor cell differentiation GO:0042491 32 16 1,000 3,991E-03 0,03392788 ! fructose metabolic process GO:0006000 25 16 1,000 3,991E-03 0,03380841 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,991E-03 0,03368979 ! neuron recognition GO:0008038 35 16 1,000 3,991E-03 0,03357199 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 3,991E-03 0,03345502 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,991E-03 0,03333885 ! defense response to virus GO:0051607 37 16 1,000 3,991E-03 0,03322349 ! positive regulation of caspase activity GO:0043280 95 55 2,000 4,317E-03 0,03581919 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 4,317E-03 0,0356961 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 4,317E-03 0,03557385 ! negative regulation of cell motion GO:0051271 134 55 2,000 4,317E-03 0,03545244 ! metencephalon development GO:0022037 30 17 1,000 4,505E-03 0,03686886 ! adult walking behavior GO:0007628 33 17 1,000 4,505E-03 0,03674388 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,505E-03 0,03661974 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,505E-03 0,03649644 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,505E-03 0,03637397 ! regulation of striated muscle contraction GO:0006942 21 17 1,000 4,505E-03 0,03625232 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,505E-03 0,03613148 ! regulation of protein binding GO:0043393 33 17 1,000 4,505E-03 0,03601144 ! genitalia development GO:0048806 30 17 1,000 4,505E-03 0,0358922 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,505E-03 0,03577374 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 4,505E-03 0,03565606 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,505E-03 0,03553916 ! RNA 3'-end processing GO:0031123 34 17 1,000 4,505E-03 0,03542302 ! regulation of DNA replication GO:0006275 101 56 2,000 4,542E-03 0,03559648 ! regulation of bone remodeling GO:0046850 137 57 2,000 4,774E-03 0,0372903 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,774E-03 0,03716962 ! regulation of tissue remodeling GO:0034103 140 58 2,000 5,012E-03 0,0389019 ! regulation of endocytosis GO:0030100 91 58 2,000 5,012E-03 0,03877681 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,049E-03 0,03893247 ! positive regulation of proteolysis GO:0045862 31 18 1,000 5,049E-03 0,03880808 ! epidermis morphogenesis GO:0048730 40 18 1,000 5,049E-03 0,03868449 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,049E-03 0,03856168 ! DNA catabolic process GO:0006308 86 59 2,000 5,258E-03 0,04003414 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 5,511E-03 0,04182698 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 5,511E-03 0,04169544 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 5,511E-03 0,04156474 ! negative regulation of defense response GO:0031348 25 19 1,000 5,621E-03 0,04225995 ! lipid phosphorylation GO:0046834 35 19 1,000 5,621E-03 0,0421283 ! pigmentation during development GO:0048066 41 19 1,000 5,621E-03 0,04199747 ! cellular pigmentation GO:0033059 36 19 1,000 5,621E-03 0,04186745 ! G1 phase GO:0051318 40 19 1,000 5,621E-03 0,04173823 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,621E-03 0,0416098 ! regulation of protein complex assembly GO:0043254 117 61 2,000 5,771E-03 0,04259143 ! regulation of homeostatic process GO:0032844 134 62 2,000 6,038E-03 0,04442777 ! transcription from RNA polymerase III promoter GO:0006383 41 20 1,000 6,221E-03 0,04563218 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,221E-03 0,04549348 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 35 20 1,000 6,221E-03 0,04535563 ! diencephalon development GO:0021536 34 20 1,000 6,221E-03 0,0452186 ! inner ear receptor cell differentiation GO:0060113 37 20 1,000 6,221E-03 0,0450824 ! ovarian follicle development GO:0001541 35 21 1,000 6,849E-03 0,04948528 ! cell aging GO:0007569 44 21 1,000 6,849E-03 0,04933712 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 6,849E-03 0,04918984 ! oogenesis GO:0048477 36 21 1,000 6,849E-03 0,04904344 ! DNA modification GO:0006304 34 21 1,000 6,849E-03 0,04889791 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 6,849E-03 0,04875324 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 6,849E-03 0,04860943 ! response to cytokine stimulus GO:0034097 63 21 1,000 6,849E-03 0,04846646 ! gut development GO:0048565 39 21 1,000 6,849E-03 0,04832433 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 6,884E-03 0,04842938 ! extracellular matrix organization GO:0030198 133 66 2,000 7,181E-03 0,05036969 ! negative regulation of cell growth GO:0030308 132 67 2,000 7,485E-03 0,05235104 ! lung development GO:0030324 144 67 2,000 7,485E-03 0,0521993 ! homeostasis of number of cells GO:0048872 114 67 2,000 7,485E-03 0,05204843 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 7,505E-03 0,05203477 ! regeneration GO:0031099 41 22 1,000 7,505E-03 0,05188525 ! mechanoreceptor differentiation GO:0042490 40 22 1,000 7,505E-03 0,05173658 ! central nervous system neuron development GO:0021954 46 22 1,000 7,505E-03 0,05158876 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 7,505E-03 0,05144179 ! apoptotic nuclear changes GO:0030262 32 22 1,000 7,505E-03 0,05129564 ! ureteric bud development GO:0001657 43 22 1,000 7,505E-03 0,05115033 ! renal system process GO:0003014 41 22 1,000 7,505E-03 0,05100584 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 7,797E-03 0,05284173 ! negative regulation of cell size GO:0045792 134 69 2,000 8,116E-03 0,05485133 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 8,187E-03 0,05517909 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 8,187E-03 0,05502496 ! visual behavior GO:0007632 42 23 1,000 8,187E-03 0,05487168 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,187E-03 0,05471926 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 8,187E-03 0,05456769 ! sex determination GO:0007530 47 23 1,000 8,187E-03 0,05441695 ! regulation of viral reproduction GO:0050792 38 23 1,000 8,187E-03 0,05426704 ! respiratory tube development GO:0030323 150 70 2,000 8,443E-03 0,05580668 ! humoral immune response GO:0006959 109 71 2,000 8,777E-03 0,05785913 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 8,777E-03 0,05770104 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,897E-03 0,058328 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,897E-03 0,0581695 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 8,897E-03 0,05801186 ! regulation of transmembrane transport GO:0034762 38 24 1,000 8,897E-03 0,05785507 ! vesicle docking GO:0048278 47 24 1,000 8,897E-03 0,05769913 ! multicellular organismal response to stress GO:0033555 49 24 1,000 8,897E-03 0,05754402 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 8,897E-03 0,05738975 ! lymphocyte proliferation GO:0046651 48 24 1,000 8,897E-03 0,0572363 ! leukocyte homeostasis GO:0001776 44 24 1,000 8,897E-03 0,05708367 ! protein tetramerization GO:0051262 52 24 1,000 8,897E-03 0,05693185 ! phosphoinositide metabolic process GO:0030384 128 72 2,000 9,12E-03 0,05820162 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 9,12E-03 0,05804765 ! respiratory system development GO:0060541 153 72 2,000 9,12E-03 0,05789449 ! protein amino acid alkylation GO:0008213 53 25 1,000 9,633E-03 0,06099362 GO:0006479|protein amino acid methylation, ! osteoblast differentiation GO:0001649 60 25 1,000 9,633E-03 0,06083353 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 9,633E-03 0,06067428 ! interaction with host GO:0051701 62 25 1,000 9,633E-03 0,06051586 ! liver development GO:0001889 53 25 1,000 9,633E-03 0,06035827 ! regulation of vesicle-mediated transport GO:0060627 119 75 2,000 0,01019286 0,06369874 ! embryonic pattern specification GO:0009880 44 26 1,000 0,01039556 0,06479721 ! molting cycle process GO:0022404 50 26 1,000 0,01039556 0,06462977 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01039556 0,0644632 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01039556 0,06429749 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01039556 0,06413262 ! response to estradiol stimulus GO:0032355 40 26 1,000 0,01039556 0,0639686 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01039556 0,06380541 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 0,01039556 0,06364306 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01039556 0,06348153 GO:0032943|mononuclear cell proliferation, ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01056616 0,06435995 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01056616 0,06419743 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01118371 0,06777838 ! neuron fate commitment GO:0048663 48 27 1,000 0,01118371 0,06760808 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01118371 0,06743863 ! male gonad development GO:0008584 44 27 1,000 0,01118371 0,06727004 ! response to toxin GO:0009636 47 27 1,000 0,01118371 0,06710228 ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01133632 0,06784874 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 0,01173324 0,07005005 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01199736 0,07144965 ! response to metal ion GO:0010038 140 80 2,000 0,01213808 0,07210916 ! complement activation, classical pathway GO:0006958 48 29 1,000 0,01283619 0,07606863 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01283619 0,07588173 ! cell fate determination GO:0001709 60 29 1,000 0,01283619 0,07569575 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01283619 0,07551067 ! tissue homeostasis GO:0001894 48 29 1,000 0,01283619 0,0753265 GO:0048871|multicellular organismal homeostasis, ! membrane docking GO:0022406 61 30 1,000 0,01369986 0,08019915 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01369986 0,0800045 ! response to heat GO:0009408 50 30 1,000 0,01369986 0,07981078 ! negative regulation of growth GO:0045926 155 84 2,000 0,01383713 0,08041576 ! regulation of ligase activity GO:0051340 142 84 2,000 0,01383713 0,08022199 ! one-carbon metabolic process GO:0006730 154 85 2,000 0,01428192 0,08260166 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01458805 0,0841699 ! GPI anchor biosynthetic process GO:0006506 53 31 1,000 0,01458805 0,08396854 ! ovulation cycle process GO:0022602 49 31 1,000 0,01458805 0,08376814 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 0,01458805 0,08356869 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01458805 0,08337019 ! mesoderm formation GO:0001707 69 31 1,000 0,01458805 0,08317263 ! response to inorganic substance GO:0010035 153 86 2,000 0,01473475 0,08381045 ! regulation of protein transport GO:0051223 154 87 2,000 0,01519566 0,08622819 GO:0070201|regulation of establishment of protein localization, ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01550045 0,08775079 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 0,01550045 0,08754481 ! GPI anchor metabolic process GO:0006505 56 32 1,000 0,01550045 0,08733978 ! metanephros development GO:0001656 74 32 1,000 0,01550045 0,08713572 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01550045 0,08693261 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01550045 0,08673044 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01550045 0,08652921 ! ovulation cycle GO:0042698 51 32 1,000 0,01550045 0,08632891 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01550045 0,08612953 ! post-embryonic development GO:0009791 69 33 1,000 0,01643675 0,09112168 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01643675 0,0909122 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01643675 0,09070369 ! leukocyte chemotaxis GO:0030595 50 33 1,000 0,01643675 0,09049613 GO:0060326|cell chemotaxis, ! adult locomotory behavior GO:0008344 59 33 1,000 0,01643675 0,09028952 ! sex differentiation GO:0007548 145 90 2,000 0,0166269 0,09112604 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01739662 0,09512786 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01739662 0,09491215 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01739662 0,09469742 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01739662 0,09448365 ! regulation of defense response GO:0031347 149 92 2,000 0,01762164 0,09549023 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,01813121 0,09803076 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01813121 0,09781096 ! regulation of muscle development GO:0048634 70 35 1,000 0,01837976 0,09892996 ! cytokine production GO:0001816 59 35 1,000 0,01837976 0,09870914 ! odontogenesis GO:0042476 66 35 1,000 0,01837976 0,09848929 ! female gonad development GO:0008585 58 35 1,000 0,01837976 0,09827043 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01938586 0,10341989 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01938586 0,10319108 ! regulation of protein stability GO:0031647 73 37 1,000 0,02041461 0,10842728 ! pigment metabolic process GO:0042440 80 37 1,000 0,02041461 0,10818846 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02135992 0,11294938 GO:0060538|skeletal muscle organ development, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,02146573 0,11325995 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 1,000 0,02146573 0,11301211 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02146573 0,11276536 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02146573 0,11251969 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,02146573 0,11227508 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02146573 0,11203153 ! isoprenoid metabolic process GO:0006720 66 38 1,000 0,02146573 0,11178904 ! cell cycle arrest GO:0007050 213 100 2,000 0,02192663 0,11394271 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02363382 0,12254951 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02363382 0,12228597 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 1,000 0,02363382 0,12202355 ! T cell differentiation GO:0030217 81 41 1,000 0,02475022 0,12751396 ! female gamete generation GO:0007292 61 41 1,000 0,02475022 0,12724149 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02475022 0,12697019 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02588779 0,13252343 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02704624 0,13815978 ! glucose transport GO:0015758 65 43 1,000 0,02704624 0,13786707 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02704624 0,1375756 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02704624 0,13728536 ! hexose transport GO:0008645 67 44 1,000 0,0282253 0,14296858 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 107 44 1,000 0,0282253 0,14266822 ! developmental growth GO:0048589 82 44 1,000 0,0282253 0,14236913 ! maintenance of location in cell GO:0051651 97 44 1,000 0,0282253 0,14207128 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02936821 0,14751545 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02936821 0,14720813 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02936821 0,14690208 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02936821 0,14659731 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02936821 0,14629379 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02936821 0,14599153 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02936821 0,14569052 ! polyol transport GO:0015791 12 5 0,000 0,02936821 0,14539075 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02936821 0,1450922 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02936821 0,14479488 ! response to superoxide GO:0000303 10 5 0,000 0,02936821 0,14449878 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02936821 0,14420388 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02936821 0,14391019 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02936821 0,14361769 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02936821 0,14332637 ! female meiosis GO:0007143 7 5 0,000 0,02936821 0,14303624 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02936821 0,14274728 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02936821 0,14245948 ! cobalt ion transport GO:0006824 11 5 0,000 0,02936821 0,14217284 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02936821 0,14188735 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02936821 0,14160301 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02936821 0,1413198 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02936821 0,14103773 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02936821 0,14075678 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02936821 0,14047694 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02936821 0,14019822 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02936821 0,1399206 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02936821 0,13964408 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02936821 0,13936864 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02936821 0,1390943 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02936821 0,13882103 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02936821 0,13854883 ! negative chemotaxis GO:0050919 14 5 0,000 0,02936821 0,1382777 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02936821 0,13800762 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02936821 0,1377386 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02936821 0,13747063 ! behavioral response to pain GO:0048266 9 5 0,000 0,02936821 0,13720369 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02936821 0,1369378 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02936821 0,13667293 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02936821 0,13640908 ! micturition GO:0060073 9 5 0,000 0,02936821 0,13614625 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02936821 0,13588443 ! copulation GO:0007620 9 5 0,000 0,02936821 0,13562361 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02936821 0,1353638 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02936821 0,13510498 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02936821 0,13484714 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02936821 0,13459029 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02936821 0,13433441 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02936821 0,13407951 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02936821 0,13382557 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02936821 0,13357259 ! grooming behavior GO:0007625 6 5 0,000 0,02936821 0,13332057 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02936821 0,1330695 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02936821 0,13281937 ! response to protozoan GO:0001562 10 5 0,000 0,02936821 0,13257017 ! lymph vessel development GO:0001945 10 5 0,000 0,02936821 0,13232191 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02936821 0,13207458 ! endochondral ossification GO:0001958 16 5 0,000 0,02936821 0,13182818 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02936821 0,13158269 ! parathyroid gland development GO:0060017 13 5 0,000 0,02936821 0,13133811 ! anagen GO:0042640 6 5 0,000 0,02936821 0,13109444 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02936821 0,13085167 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02936821 0,1306098 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02936821 0,13036882 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02936821 0,13012873 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02936821 0,12988953 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02936821 0,1296512 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02936821 0,12941374 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02936821 0,12917715 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02936821 0,12894143 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02936821 0,12870656 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02936821 0,12847255 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02936821 0,12823939 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02936821 0,12800707 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02936821 0,12777559 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02936821 0,12754495 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02936821 0,12731514 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02936821 0,12708616 ! histidine catabolic process GO:0006548 6 5 0,000 0,02936821 0,12685799 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02936821 0,12663065 ! microvillus organization GO:0032528 7 5 0,000 0,02936821 0,12640412 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02936821 0,1261784 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02936821 0,12595348 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02936821 0,12572936 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02936821 0,12550604 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02936821 0,12528351 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02936821 0,12506177 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02936821 0,12484082 ! polyol catabolic process GO:0046174 7 5 0,000 0,02936821 0,12462064 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02936821 0,12440124 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02936821 0,1241826 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02936821 0,12396474 ! muscle cell migration GO:0014812 8 5 0,000 0,02936821 0,12374764 ! mitochondrial fission GO:0000266 8 5 0,000 0,02936821 0,1235313 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02936821 0,12331571 ! mRNA transcription GO:0009299 9 5 0,000 0,02936821 0,12310087 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02936821 0,12288679 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02936821 0,12267344 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02936821 0,12246084 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02936821 0,12224897 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02936821 0,12203783 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02936821 0,12182742 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02936821 0,12161773 ! response to food GO:0032094 6 5 0,000 0,02936821 0,12140877 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02936821 0,12120052 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02936821 0,12099298 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02936821 0,12078616 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02936821 0,12058004 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02936821 0,12037462 ! forebrain neuron development GO:0021884 13 5 0,000 0,02936821 0,1201699 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02936821 0,11996588 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02936821 0,11976255 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02936821 0,1195599 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02936821 0,11935794 GO:0009251|glucan catabolic process, ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02936821 0,11915666 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02936821 0,11895606 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02936821 0,11875614 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02936821 0,11855688 ! basic amino acid transport GO:0015802 11 5 0,000 0,02936821 0,1183583 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02936821 0,11816037 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02936821 0,11796311 ! depyrimidination GO:0045008 10 5 0,000 0,02936821 0,1177665 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02936821 0,11757055 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02936821 0,11737525 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02936821 0,1171806 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02936821 0,11698659 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02936821 0,11679323 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02936821 0,1166005 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02936821 0,11640841 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02936821 0,11621694 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02936821 0,11602611 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02936821 0,11583591 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02936821 0,11564632 ! response to arsenic GO:0046685 10 5 0,000 0,02936821 0,11545736 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02936821 0,11526901 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02936821 0,11508127 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02936821 0,11489415 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02936821 0,11470763 ! response to cadmium ion GO:0046686 7 5 0,000 0,02936821 0,11452172 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02936821 0,11433641 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02936821 0,1141517 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02936821 0,11396758 ! decidualization GO:0046697 11 5 0,000 0,02936821 0,11378406 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02936821 0,11360113 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02936821 0,11341878 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02936821 0,11323702 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02936821 0,11305584 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02936821 0,11287524 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02936821 0,11269522 ! neural tube patterning GO:0021532 7 5 0,000 0,02936821 0,11251577 ! embryonic cleavage GO:0040016 6 5 0,000 0,02936821 0,11233689 ! peroxisome fission GO:0016559 5 5 0,000 0,02936821 0,11215857 ! histone demethylation GO:0016577 10 5 0,000 0,02936821 0,11198083 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02936821 0,11180364 ! mitotic recombination GO:0006312 9 5 0,000 0,02936821 0,11162702 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02936821 0,11145095 ! metaphase plate congression GO:0051310 7 5 0,000 0,02936821 0,11127544 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02936821 0,11110048 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02936821 0,11092606 ! enteric nervous system development GO:0048484 8 5 0,000 0,02936821 0,1107522 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02936821 0,11057888 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02936821 0,1104061 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02936821 0,11023386 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02936821 0,11006215 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02936821 0,10989098 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02936821 0,10972035 ! plasminogen activation GO:0031639 5 5 0,000 0,02936821 0,10955024 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02936821 0,10938065 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02936821 0,1092116 ! metaphase GO:0051323 8 5 0,000 0,02936821 0,10904306 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02936821 0,10887504 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02936821 0,10870754 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02936821 0,10854056 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02936821 0,10837408 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02936821 0,10820812 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02936821 0,10804266 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02936821 0,10787771 ! response to redox state GO:0051775 5 5 0,000 0,02936821 0,10771327 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02936821 0,10754932 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02936821 0,10738587 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02936821 0,10722292 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02936821 0,10706046 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02936821 0,10689849 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02936821 0,10673701 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02936821 0,10657602 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02936821 0,10641552 ! striatum development GO:0021756 9 5 0,000 0,02936821 0,10625549 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02936821 0,10609595 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02936821 0,10593688 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02936821 0,1057783 ! glial cell migration GO:0008347 11 5 0,000 0,02936821 0,10562018 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02936821 0,10546254 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02936821 0,10530537 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02936821 0,10514866 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02936821 0,10499243 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02936821 0,10483665 ! neuroprotection GO:0043526 6 5 0,000 0,02936821 0,10468134 ! neural plate development GO:0001840 8 5 0,000 0,02936821 0,10452648 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02936821 0,10437209 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02936821 0,10421814 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02936821 0,10406466 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02936821 0,10391162 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02936821 0,10375903 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02936821 0,10360689 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02936821 0,1034552 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02936821 0,10330395 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02936821 0,10315314 ! spindle assembly GO:0051225 6 5 0,000 0,02936821 0,10300277 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02936821 0,10285284 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02936821 0,10270335 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02936821 0,10255428 ! drug metabolic process GO:0017144 6 5 0,000 0,02936821 0,10240566 ! stem cell division GO:0017145 11 5 0,000 0,02936821 0,10225746 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02936821 0,10210969 ! organ regeneration GO:0031100 7 5 0,000 0,02936821 0,10196234 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02936821 0,10181542 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02936821 0,10166892 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02936821 0,10152285 ! glycolysis GO:0006096 65 45 1,000 0,02942468 0,10157213 ! leukocyte migration GO:0050900 68 45 1,000 0,02942468 0,10142662 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02942468 0,10128151 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02942468 0,10113682 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,0306441 0,10517788 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,0306441 0,10502805 ! positive regulation of defense response GO:0031349 76 47 1,000 0,03188327 0,10911971 ! response to calcium ion GO:0051592 81 47 1,000 0,03188327 0,10896471 ! JNK cascade GO:0007254 91 47 1,000 0,03188327 0,10881015 ! mitochondrial transport GO:0006839 82 48 1,000 0,03314194 0,11294547 ! Notch signaling pathway GO:0007219 96 48 1,000 0,03314194 0,11278572 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,03441981 0,11696903 ! regulation of action potential GO:0001508 95 49 1,000 0,03441981 0,11680405 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,03441981 0,11663954 ! peptide metabolic process GO:0006518 76 49 1,000 0,03441981 0,11647549 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03441981 0,1163119 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,03441981 0,11614877 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03441981 0,1159861 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0351381 0,11824094 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0351381 0,1180758 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0351381 0,11791112 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0351381 0,1177469 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0351381 0,11758313 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0351381 0,11741982 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0351381 0,11725696 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0351381 0,11709456 ! sleep GO:0030431 13 6 0,000 0,0351381 0,1169326 ! response to oxygen radical GO:0000305 11 6 0,000 0,0351381 0,11677109 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0351381 0,11661003 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0351381 0,11644941 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0351381 0,11628923 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0351381 0,11612949 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0351381 0,11597019 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0351381 0,11581133 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0351381 0,1156529 ! forebrain regionalization GO:0021871 8 6 0,000 0,0351381 0,11549491 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0351381 0,11533734 ! male meiosis GO:0007140 7 6 0,000 0,0351381 0,11518021 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0351381 0,1150235 ! response to zinc ion GO:0010043 9 6 0,000 0,0351381 0,11486722 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0351381 0,11471136 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0351381 0,11455592 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0351381 0,11440091 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0351381 0,11424631 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0351381 0,11409213 ! malate metabolic process GO:0006108 11 6 0,000 0,0351381 0,11393837 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0351381 0,11378502 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0351381 0,11363208 ! protein refolding GO:0042026 15 6 0,000 0,0351381 0,11347956 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0351381 0,11332744 ! opsonization GO:0008228 8 6 0,000 0,0351381 0,11317573 ! mating behavior GO:0007617 7 6 0,000 0,0351381 0,11302443 ! neuron remodeling GO:0016322 15 6 0,000 0,0351381 0,11287353 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0351381 0,11272303 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0351381 0,11257293 ! equilibrioception GO:0050957 14 6 0,000 0,0351381 0,11242323 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0351381 0,11227393 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0351381 0,11212503 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0351381 0,11197652 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0351381 0,1118284 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0351381 0,11168067 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0351381 0,11153334 ! toxin metabolic process GO:0009404 11 6 0,000 0,0351381 0,11138639 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0351381 0,11123983 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0351381 0,11109365 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0351381 0,11094786 ! nuclear migration GO:0007097 12 6 0,000 0,0351381 0,11080245 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0351381 0,11065742 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0351381 0,11051277 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0351381 0,1103685 ! thymic T cell selection GO:0045061 12 6 0,000 0,0351381 0,1102246 ! protein lipoylation GO:0009249 10 6 0,000 0,0351381 0,11008108 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0351381 0,10993793 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0351381 0,10979516 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0351381 0,10965275 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0351381 0,10951071 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0351381 0,10936904 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,0351381 0,10922774 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0351381 0,1090868 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0351381 0,10894623 ! hyperosmotic response GO:0006972 9 6 0,000 0,0351381 0,10880601 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0351381 0,10866616 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0351381 0,10852666 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0351381 0,10838753 ! urea metabolic process GO:0019627 7 6 0,000 0,0351381 0,10824875 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0351381 0,10811032 ! neutrophil activation GO:0042119 8 6 0,000 0,0351381 0,10797225 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0351381 0,10783453 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0351381 0,10769716 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0351381 0,10756014 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0351381 0,10742347 ! neuron apoptosis GO:0051402 9 6 0,000 0,0351381 0,10728715 ! nucleoside salvage GO:0043174 9 6 0,000 0,0351381 0,10715117 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0351381 0,10701553 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0351381 0,10688024 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0351381 0,10674529 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0351381 0,10661068 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0351381 0,10647641 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0351381 0,10634248 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0351381 0,10620888 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0351381 0,10607562 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0351381 0,1059427 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0351381 0,1058101 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0351381 0,10567784 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0351381 0,10554591 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0351381 0,1054143 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0351381 0,10528303 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0351381 0,10515208 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0351381 0,10502145 ! response to UV-C GO:0010225 11 6 0,000 0,0351381 0,10489115 ! astrocyte development GO:0014002 15 6 0,000 0,0351381 0,10476118 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0351381 0,10463152 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0351381 0,10450219 ! interaction with symbiont GO:0051702 13 6 0,000 0,0351381 0,10437317 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0351381 0,10424448 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0351381 0,1041161 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0351381 0,10398803 ! response to copper ion GO:0046688 10 6 0,000 0,0351381 0,10386028 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0351381 0,10373285 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0351381 0,10360572 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0351381 0,10347891 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0351381 0,10335241 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0351381 0,10322622 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0351381 0,10310033 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0351381 0,10297475 ! hair follicle maturation GO:0048820 7 6 0,000 0,0351381 0,10284948 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0351381 0,10272451 ! Schwann cell development GO:0014044 15 6 0,000 0,0351381 0,10259984 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0351381 0,10247548 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0351381 0,10235142 ! subpallium development GO:0021544 10 6 0,000 0,0351381 0,10222765 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0351381 0,10210419 ! histone ubiquitination GO:0016574 8 6 0,000 0,0351381 0,10198103 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0351381 0,10185816 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0351381 0,10173558 ! G2 phase GO:0051319 16 6 0,000 0,0351381 0,10161331 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0351381 0,10149132 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0351381 0,10136963 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0351381 0,10124823 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0351381 0,10112712 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0351381 0,1010063 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0351381 0,10088576 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0351381 0,10076552 ! receptor internalization GO:0031623 10 6 0,000 0,0351381 0,10064556 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0351381 0,10052589 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0351381 0,1004065 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0351381 0,10028739 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0351381 0,10016857 ! protein deubiquitination GO:0016579 14 6 0,000 0,0351381 0,10005002 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,0351381 0,09993176 ! protein destabilization GO:0031648 9 6 0,000 0,0351381 0,09981378 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0351381 0,09969607 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0351381 0,09957865 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0351381 0,09946149 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0351381 0,09934462 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0351381 0,09922802 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0351381 0,09911169 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0351381 0,09899563 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0351381 0,09887985 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0351381 0,09876433 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0351381 0,09864909 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0351381 0,09853411 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0351381 0,09841941 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0351381 0,09830497 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0351381 0,09819079 ! catecholamine transport GO:0051937 9 6 0,000 0,0351381 0,09807688 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0351381 0,09796323 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0351381 0,09784985 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0351381 0,09773673 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0351381 0,09762387 ! maternal placenta development GO:0001893 12 6 0,000 0,0351381 0,09751127 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0351381 0,09739893 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0351381 0,09728685 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,0351381 0,09717502 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0351381 0,09706346 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0351381 0,09695215 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0351381 0,09684109 ! histone modification GO:0016570 91 50 1,000 0,03571663 0,09832291 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03571663 0,09821054 ! excretion GO:0007588 83 51 1,000 0,03703213 0,10171154 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03703213 0,10159556 ! chromatin remodeling GO:0006338 109 51 1,000 0,03703213 0,10147985 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03703213 0,1013644 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03836604 0,10489623 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03836604 0,10477717 ! amino acid activation GO:0043038 92 52 1,000 0,03836604 0,10465837 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,03971809 0,10822393 ! cell maturation GO:0048469 100 53 1,000 0,03971809 0,1081015 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03971809 0,10797936 ! response to UV GO:0009411 104 53 1,000 0,03971809 0,10785748 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04087389 0,110871 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04087389 0,11074614 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04087389 0,11062157 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04087389 0,11049727 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04087389 0,11037326 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04087389 0,11024952 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04087389 0,11012606 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04087389 0,11000288 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04087389 0,10987997 ! prostate gland development GO:0030850 13 7 0,000 0,04087389 0,10975734 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04087389 0,10963498 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04087389 0,10951289 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04087389 0,10939107 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04087389 0,10926953 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04087389 0,10914825 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04087389 0,10902724 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04087389 0,1089065 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04087389 0,10878603 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04087389 0,10866583 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04087389 0,10854589 ! glycolipid transport GO:0046836 10 7 0,000 0,04087389 0,10842621 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04087389 0,1083068 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04087389 0,10818765 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04087389 0,10806876 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04087389 0,10795014 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04087389 0,10783177 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04087389 0,10771366 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04087389 0,10759581 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04087389 0,10747822 ! mRNA stabilization GO:0048255 18 7 0,000 0,04087389 0,10736089 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04087389 0,10724381 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04087389 0,10712699 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04087389 0,10701042 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04087389 0,1068941 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04087389 0,10677804 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04087389 0,10666223 ! lipoprotein transport GO:0042953 14 7 0,000 0,04087389 0,10654667 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04087389 0,10643136 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04087389 0,1063163 ! rhythmic behavior GO:0007622 15 7 0,000 0,04087389 0,10620148 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04087389 0,10608692 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04087389 0,1059726 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04087389 0,10585853 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04087389 0,1057447 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04087389 0,10563112 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04087389 0,10551778 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04087389 0,10540469 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04087389 0,10529184 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04087389 0,10517922 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04087389 0,10506685 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04087389 0,10495472 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04087389 0,10484283 ! spinal cord patterning GO:0021511 13 7 0,000 0,04087389 0,10473118 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04087389 0,10461976 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04087389 0,10450858 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04087389 0,10439764 ! adrenal gland development GO:0030325 17 7 0,000 0,04087389 0,10428693 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04087389 0,10417646 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04087389 0,10406622 ! ovulation GO:0030728 9 7 0,000 0,04087389 0,10395621 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04087389 0,10384644 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04087389 0,10373689 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04087389 0,10362758 ! microtubule nucleation GO:0007020 20 7 0,000 0,04087389 0,1035185 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04087389 0,10340965 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04087389 0,10330102 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04087389 0,10319263 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04087389 0,10308446 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04087389 0,10297652 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04087389 0,1028688 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04087389 0,10276131 ! galactose metabolic process GO:0006012 13 7 0,000 0,04087389 0,10265404 ! response to dietary excess GO:0002021 8 7 0,000 0,04087389 0,102547 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04087389 0,10244018 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04087389 0,10233358 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04087389 0,10222721 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04087389 0,10212105 ! purine salvage GO:0043101 10 7 0,000 0,04087389 0,10201512 ! nucleoside transport GO:0015858 8 7 0,000 0,04087389 0,1019094 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04087389 0,10180391 ! parturition GO:0007567 14 7 0,000 0,04087389 0,10169863 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04087389 0,10159357 ! rRNA modification GO:0000154 14 7 0,000 0,04087389 0,10148872 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04087389 0,1013841 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04087389 0,10127968 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04087389 0,10117549 ! macrophage differentiation GO:0030225 11 7 0,000 0,04087389 0,1010715 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04087389 0,10096774 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04087389 0,10086418 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04087389 0,10076083 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04087389 0,1006577 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04087389 0,10055478 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04087389 0,10045207 ! fibrinolysis GO:0042730 10 7 0,000 0,04087389 0,10034957 ! eating behavior GO:0042755 7 7 0,000 0,04087389 0,10024727 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04087389 0,10014519 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04087389 0,10004331 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04087389 0,09994164 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04087389 0,09984018 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04087389 0,09973892 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04087389 0,09963787 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04087389 0,09953702 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04087389 0,09943637 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04087389 0,09933593 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04087389 0,0992357 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04087389 0,09913566 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04087389 0,09903582 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04087389 0,09893619 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04087389 0,09883676 ! regulation of meiosis GO:0040020 12 7 0,000 0,04087389 0,09873752 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04087389 0,09863849 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04087389 0,09853965 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04087389 0,09844101 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04087389 0,09834257 ! transcription termination GO:0006353 13 7 0,000 0,04087389 0,09824433 ! response to tumor cell GO:0002347 13 7 0,000 0,04087389 0,09814628 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04087389 0,09804843 ! anaphase GO:0051322 17 7 0,000 0,04087389 0,09795077 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 18 7 0,000 0,04087389 0,09785331 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04087389 0,09775604 ! diuresis GO:0030146 12 7 0,000 0,04087389 0,09765896 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04087389 0,09756208 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04087389 0,09746539 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04087389 0,09736889 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04087389 0,09727258 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04087389 0,09717646 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04087389 0,09708053 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04087389 0,09698479 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04087389 0,09688924 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04087389 0,09679387 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04087389 0,0966987 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04087389 0,09660371 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04087389 0,0965089 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04087389 0,09641429 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04087389 0,09631986 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04087389 0,09622561 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04087389 0,09613155 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04087389 0,09603767 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04087389 0,09594397 ! adult feeding behavior GO:0008343 9 7 0,000 0,04087389 0,09585046 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04087389 0,09575713 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04087389 0,09566398 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04087389 0,09557101 ! muscle adaptation GO:0043500 14 7 0,000 0,04087389 0,09547823 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04087389 0,09538562 ! retina homeostasis GO:0001895 12 7 0,000 0,04087389 0,09529319 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04087389 0,09520094 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04087389 0,09510887 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04087389 0,09501698 ! protein prenylation GO:0018342 18 7 0,000 0,04087389 0,09492526 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04087389 0,09483373 ! cell recognition GO:0008037 85 54 1,000 0,04108803 0,09523874 ! glucose catabolic process GO:0006007 82 55 1,000 0,04247561 0,09836026 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04247561 0,09826568 ! aging GO:0007568 103 55 1,000 0,04247561 0,09817129 ! gastrulation GO:0007369 112 55 1,000 0,04247561 0,09807707 ! heart morphogenesis GO:0003007 97 55 1,000 0,04247561 0,09798304 ! RNA elongation GO:0006354 79 55 1,000 0,04247561 0,09788919 ! nuclear export GO:0051168 97 55 1,000 0,04247561 0,09779551 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04388056 0,10093367 ! lipid modification GO:0030258 97 57 1,000 0,04530262 0,10410517 ! maintenance of location GO:0051235 118 57 1,000 0,04530262 0,10400583 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04657577 0,10682678 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04657577 0,10672504 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04657577 0,1066235 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04657577 0,10652214 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04657577 0,10642098 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04657577 0,10632001 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04657577 0,10621924 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04657577 0,10611865 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04657577 0,10601825 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04657577 0,10591805 ! meiotic prophase I GO:0007128 13 8 0,000 0,04657577 0,10581803 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04657577 0,1057182 ! oligopeptide transport GO:0006857 15 8 0,000 0,04657577 0,10561856 ! UTP metabolic process GO:0046051 8 8 0,000 0,04657577 0,10551911 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04657577 0,10541984 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04657577 0,10532077 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04657577 0,10522187 ! succinate metabolic process GO:0006105 14 8 0,000 0,04657577 0,10512317 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04657577 0,10502464 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04657577 0,10492631 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04657577 0,10482815 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04657577 0,10473018 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04657577 0,10463239 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04657577 0,10453479 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04657577 0,10443737 ! reflex GO:0060004 16 8 0,000 0,04657577 0,10434013 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04657577 0,10424306 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04657577 0,10414618 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04657577 0,10404948 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04657577 0,10395296 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04657577 0,10385662 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04657577 0,10376046 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04657577 0,10366447 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04657577 0,10356866 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04657577 0,10347303 ! histidine metabolic process GO:0006547 16 8 0,000 0,04657577 0,10337758 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04657577 0,1032823 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04657577 0,1031872 ! glycine catabolic process GO:0006546 13 8 0,000 0,04657577 0,10309227 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04657577 0,10299751 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04657577 0,10290293 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04657577 0,10280853 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04657577 0,10271429 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04657577 0,10262023 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04657577 0,10252634 ! macrophage activation GO:0042116 12 8 0,000 0,04657577 0,10243263 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04657577 0,10233908 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04657577 0,10224571 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04657577 0,1021525 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04657577 0,10205947 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04657577 0,1019666 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04657577 0,1018739 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04657577 0,10178138 ! osteoblast development GO:0002076 16 8 0,000 0,04657577 0,10168902 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04657577 0,10159682 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04657577 0,1015048 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04657577 0,10141294 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04657577 0,10132124 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04657577 0,10122972 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04657577 0,10113835 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04657577 0,10104715 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04657577 0,10095612 ! intermediate filament organization GO:0045109 12 8 0,000 0,04657577 0,10086525 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04657577 0,10077455 ! cellular extravasation GO:0045123 12 8 0,000 0,04657577 0,100684 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04657577 0,10059362 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04657577 0,1005034 ! response to antibiotic GO:0046677 11 8 0,000 0,04657577 0,10041335 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04657577 0,10032345 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04657577 0,10023372 ! DNA topological change GO:0006265 12 8 0,000 0,04657577 0,10014414 ! response to tropane GO:0014073 15 8 0,000 0,04657577 0,10005473 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04657577 0,09996547 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,04657577 0,09987638 ! melanosome transport GO:0032402 13 8 0,000 0,04657577 0,09978744 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04657577 0,09969866 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04657577 0,09961004 ! mast cell activation GO:0045576 14 8 0,000 0,04657577 0,09952158 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04657577 0,09943327 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04657577 0,09934512 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04657577 0,09925713 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04657577 0,09916929 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04657577 0,0990816 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04657577 0,09899408 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04657577 0,0989067 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04657577 0,09881948 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04657577 0,09873242 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04657577 0,09864551 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04657577 0,09855875 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04657577 0,09847214 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04657577 0,09838568 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04657577 0,09829938 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04657577 0,09821323 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04657577 0,09812723 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04657577 0,09804138 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04657577 0,09795568 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04657577 0,09787013 ! hormone catabolic process GO:0042447 17 8 0,000 0,04657577 0,09778472 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04657577 0,09769947 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04657577 0,09761437 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04657577 0,09752941 ! ATP catabolic process GO:0006200 11 8 0,000 0,04657577 0,0974446 ! blastocyst growth GO:0001832 19 8 0,000 0,04657577 0,09735994 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04657577 0,09727543 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04657577 0,09719106 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04657577 0,09710684 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04657577 0,09702277 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04657577 0,09693884 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04657577 0,09685505 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04657577 0,09677141 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04657577 0,09668792 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04657577 0,09660456 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04657577 0,09652136 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04657577 0,09643829 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04657577 0,09635537 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04657577 0,09627259 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04657577 0,09618995 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04657577 0,09610746 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04657577 0,0960251 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04657577 0,09594289 ! adult behavior GO:0030534 99 58 1,000 0,04674156 0,09620206 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04819713 0,09911307 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,04819713 0,09902843 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04819713 0,09894393 ! regulation of heart contraction GO:0008016 110 60 1,000 0,04966907 0,10187875 ! kidney development GO:0001822 122 60 1,000 0,04966907 0,10179197 ! glycerophospholipid biosynthetic process GO:0046474 105 61 1,000 0,05115714 0,10475241 ! mesoderm development GO:0007498 119 61 1,000 0,05115714 0,10466333 ! tRNA processing GO:0008033 89 61 1,000 0,05115714 0,10457441 ! axon extension GO:0048675 15 9 0,000 0,05224394 0,10670536 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05224394 0,10661485 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05224394 0,1065245 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05224394 0,1064343 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05224394 0,10634426 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05224394 0,10625436 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05224394 0,10616462 ! phosphate transport GO:0006817 19 9 0,000 0,05224394 0,10607503 ! reproductive behavior GO:0019098 19 9 0,000 0,05224394 0,10598559 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05224394 0,1058963 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05224394 0,10580717 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05224394 0,10571818 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05224394 0,10562934 ! GTP metabolic process GO:0046039 9 9 0,000 0,05224394 0,10554065 ! RNA methylation GO:0001510 15 9 0,000 0,05224394 0,10545211 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05224394 0,10536372 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05224394 0,10527547 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05224394 0,10518737 ! artery development GO:0060840 24 9 0,000 0,05224394 0,10509942 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05224394 0,10501162 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05224394 0,10492397 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05224394 0,10483646 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05224394 0,10474909 ! chemosensory behavior GO:0007635 20 9 0,000 0,05224394 0,10466188 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05224394 0,1045748 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05224394 0,10448787 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05224394 0,10440109 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05224394 0,10431445 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05224394 0,10422795 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05224394 0,1041416 ! protein targeting to ER GO:0045047 22 9 0,000 0,05224394 0,10405539 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05224394 0,10396932 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05224394 0,1038834 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05224394 0,10379762 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05224394 0,10371197 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05224394 0,10362647 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05224394 0,10354111 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05224394 0,10345589 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05224394 0,10337082 ! mannose metabolic process GO:0006013 13 9 0,000 0,05224394 0,10328588 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05224394 0,10320108 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05224394 0,10311642 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05224394 0,1030319 ! receptor clustering GO:0043113 18 9 0,000 0,05224394 0,10294751 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05224394 0,10286327 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05224394 0,10277916 ! ruffle organization GO:0031529 15 9 0,000 0,05224394 0,10269519 ! retinol metabolic process GO:0042572 18 9 0,000 0,05224394 0,10261136 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05224394 0,10252766 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05224394 0,1024441 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05224394 0,10236068 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05224394 0,10227739 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,05224394 0,10219424 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05224394 0,10211122 ! segment specification GO:0007379 13 9 0,000 0,05224394 0,10202834 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05224394 0,10194559 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05224394 0,10186298 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05224394 0,1017805 ! response to amine stimulus GO:0014075 13 9 0,000 0,05224394 0,10169815 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05224394 0,10161594 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05224394 0,10153385 ! erythrocyte development GO:0048821 15 9 0,000 0,05224394 0,10145191 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05224394 0,10137009 ! renal water homeostasis GO:0003091 14 9 0,000 0,05224394 0,10128841 ! postreplication repair GO:0006301 22 9 0,000 0,05224394 0,10120685 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05224394 0,10112543 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05224394 0,10104414 ! icosanoid secretion GO:0032309 15 9 0,000 0,05224394 0,10096298 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05224394 0,10088195 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05224394 0,10080105 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05224394 0,10072028 ! regulation of cell division GO:0051302 15 9 0,000 0,05224394 0,10063964 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05224394 0,10055913 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05224394 0,10047875 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05224394 0,10039849 ! sterol catabolic process GO:0016127 11 9 0,000 0,05224394 0,10031837 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05224394 0,10023837 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05224394 0,1001585 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05224394 0,10007875 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05224394 0,09999913 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05224394 0,09991964 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05224394 0,09984028 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05224394 0,09976104 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05224394 0,09968193 ! purine base metabolic process GO:0006144 21 9 0,000 0,05224394 0,09960294 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05224394 0,09952408 ! pigment granule transport GO:0051904 17 9 0,000 0,05224394 0,09944534 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05224394 0,09936673 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05224394 0,09928824 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05224394 0,09920988 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05224394 0,09913163 ! mitochondrion localization GO:0051646 15 9 0,000 0,05224394 0,09905352 ! viral reproductive process GO:0022415 126 62 1,000 0,05266111 0,09976584 ! gonad development GO:0008406 98 62 1,000 0,05266111 0,09968735 ! detection of external stimulus GO:0009581 91 63 1,000 0,05418072 0,10248335 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,05418072 0,10240284 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,05418072 0,10232247 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,05571576 0,10513891 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,05571576 0,10505651 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,05571576 0,10497425 GO:0048609|reproductive process in a multicellular organism, ! germ cell development GO:0007281 118 65 1,000 0,05726597 0,10781059 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,05726597 0,10772629 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0578786 0,10879367 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,0578786 0,10870875 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0578786 0,10862395 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0578786 0,10853929 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,0578786 0,10845475 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0578786 0,10837035 ! synapsis GO:0007129 13 10 0,000 0,0578786 0,10828608 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0578786 0,10820195 ! N-glycan processing GO:0006491 20 10 0,000 0,0578786 0,10811794 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0578786 0,10803406 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0578786 0,10795031 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0578786 0,1078667 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0578786 0,10778321 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0578786 0,10769985 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0578786 0,10761662 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0578786 0,10753352 ! androgen metabolic process GO:0008209 17 10 0,000 0,0578786 0,10745054 ! phospholipid efflux GO:0033700 16 10 0,000 0,0578786 0,1073677 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0578786 0,10728498 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0578786 0,10720239 ! lung alveolus development GO:0048286 26 10 0,000 0,0578786 0,10711993 ! pathogenesis GO:0009405 13 10 0,000 0,0578786 0,10703759 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0578786 0,10695538 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0578786 0,1068733 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0578786 0,10679134 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0578786 0,1067095 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0578786 0,1066278 ! endoderm development GO:0007492 16 10 0,000 0,0578786 0,10654622 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0578786 0,10646476 ! arginine catabolic process GO:0006527 13 10 0,000 0,0578786 0,10638343 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0578786 0,10630222 ! proline metabolic process GO:0006560 13 10 0,000 0,0578786 0,10622113 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0578786 0,10614017 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0578786 0,10605933 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0578786 0,10597862 ! V(D)J recombination GO:0033151 28 10 0,000 0,0578786 0,10589803 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0578786 0,10581756 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0578786 0,10573721 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0578786 0,10565698 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0578786 0,10557688 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0578786 0,1054969 ! multicellular organism growth GO:0035264 18 10 0,000 0,0578786 0,10541704 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0578786 0,10533729 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0578786 0,10525767 ! epithelial cell development GO:0002064 20 10 0,000 0,0578786 0,10517817 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0578786 0,1050988 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0578786 0,10501954 ! macroautophagy GO:0016236 17 10 0,000 0,0578786 0,10494039 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0578786 0,10486137 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0578786 0,10478247 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0578786 0,10470369 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0578786 0,10462502 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0578786 0,10454647 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0578786 0,10446804 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0578786 0,10438973 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0578786 0,10431154 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0578786 0,10423346 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0578786 0,1041555 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0578786 0,10407766 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0578786 0,10399993 ! DNA ligation GO:0006266 19 10 0,000 0,0578786 0,10392232 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0578786 0,10384482 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0578786 0,10376744 ! melanosome localization GO:0032400 16 10 0,000 0,0578786 0,10369017 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0578786 0,10361302 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0578786 0,10353599 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0578786 0,10345907 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0578786 0,10338226 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0578786 0,10330557 ! mRNA cleavage GO:0006379 17 10 0,000 0,0578786 0,10322899 ! protein sumoylation GO:0016925 15 10 0,000 0,0578786 0,10315252 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0578786 0,10307617 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0578786 0,10299993 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0578786 0,1029238 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0578786 0,10284779 ! salivary gland development GO:0007431 27 10 0,000 0,0578786 0,10277188 ! prophase GO:0051324 15 10 0,000 0,0578786 0,10269609 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0578786 0,10262042 ! apical protein localization GO:0045176 15 10 0,000 0,0578786 0,10254485 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0578786 0,10246939 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0578786 0,10239405 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0578786 0,10231881 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0578786 0,10224369 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0578786 0,10216867 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0578786 0,10209377 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0578786 0,10201898 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0578786 0,10194429 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0578786 0,10186972 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0578786 0,10179525 ! detection of calcium ion GO:0005513 23 10 0,000 0,0578786 0,10172089 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0578786 0,10164664 ! blastocyst formation GO:0001825 17 10 0,000 0,0578786 0,1015725 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0578786 0,10149847 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0578786 0,10142455 ! activation of innate immune response GO:0002218 12 10 0,000 0,0578786 0,10135073 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0578786 0,10127702 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0578786 0,10120342 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0578786 0,10112992 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0578786 0,10105653 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0578786 0,10098325 ! localization within membrane GO:0051668 20 10 0,000 0,0578786 0,10091008 ! secondary metabolic process GO:0019748 116 66 1,000 0,05883114 0,10249654 ! developmental maturation GO:0021700 116 66 1,000 0,05883114 0,10242237 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06041102 0,10509683 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,06041102 0,10502089 ! hexose catabolic process GO:0019320 104 67 1,000 0,06041102 0,10494506 ! adaptive immune response GO:0002250 119 67 1,000 0,06041102 0,10486935 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,06041102 0,10479374 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,06200539 0,10748197 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,06200539 0,10740459 ! viral reproduction GO:0016032 134 68 1,000 0,06200539 0,10732732 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06347994 0,10980068 ! respiratory burst GO:0045730 17 11 0,000 0,06347994 0,1097218 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06347994 0,10964303 ! neuron fate specification GO:0048665 17 11 0,000 0,06347994 0,10956438 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06347994 0,10948584 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06347994 0,10940741 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06347994 0,10932909 ! thyroid gland development GO:0030878 26 11 0,000 0,06347994 0,10925089 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,06347994 0,1091728 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06347994 0,10909482 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06347994 0,10901695 ! response to pain GO:0048265 24 11 0,000 0,06347994 0,10893919 ! T cell proliferation GO:0042098 26 11 0,000 0,06347994 0,10886154 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06347994 0,108784 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06347994 0,10870658 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06347994 0,10862926 ! bone resorption GO:0045453 16 11 0,000 0,06347994 0,10855206 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06347994 0,10847496 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06347994 0,10839797 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06347994 0,10832109 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06347994 0,10824433 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06347994 0,10816766 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06347994 0,10809111 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06347994 0,10801467 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06347994 0,10793833 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06347994 0,10786211 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06347994 0,10778599 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06347994 0,10770997 ! lipid digestion GO:0044241 18 11 0,000 0,06347994 0,10763407 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06347994 0,10755827 ! UV protection GO:0009650 19 11 0,000 0,06347994 0,10748258 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06347994 0,10740699 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06347994 0,10733151 ! temperature homeostasis GO:0001659 17 11 0,000 0,06347994 0,10725614 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06347994 0,10718087 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06347994 0,10710571 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06347994 0,10703065 ! regulation of organ growth GO:0046620 13 11 0,000 0,06347994 0,1069557 ! pigment granule localization GO:0051875 20 11 0,000 0,06347994 0,10688086 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06347994 0,10680611 ! vasoconstriction GO:0042310 18 11 0,000 0,06347994 0,10673148 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06347994 0,10665694 ! embryonic axis specification GO:0000578 18 11 0,000 0,06347994 0,10658251 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06347994 0,10650819 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06347994 0,10643397 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06347994 0,10635985 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06347994 0,10628583 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06347994 0,10621192 ! zymogen activation GO:0031638 15 11 0,000 0,06347994 0,10613811 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06347994 0,1060644 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06347994 0,1059908 ! nucleosome positioning GO:0016584 15 11 0,000 0,06347994 0,1059173 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06347994 0,1058439 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06347994 0,1057706 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06347994 0,1056974 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06347994 0,1056243 ! acid secretion GO:0046717 18 11 0,000 0,06347994 0,10555131 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06347994 0,10547841 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06347994 0,10540562 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06347994 0,10533293 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06347994 0,10526033 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06347994 0,10518784 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06347994 0,10511545 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06347994 0,10504315 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06347994 0,10497096 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06347994 0,10489886 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06347994 0,10482687 ! embryonic gut development GO:0048566 15 11 0,000 0,06347994 0,10475497 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06347994 0,10468317 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06347994 0,10461147 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06347994 0,10453986 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06347994 0,10446836 ! defense response to fungus GO:0050832 13 11 0,000 0,06347994 0,10439695 ! developmental induction GO:0031128 19 11 0,000 0,06347994 0,10432564 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06347994 0,10425443 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06347994 0,10418332 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06347994 0,1041123 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06347994 0,10404138 ! nucleus localization GO:0051647 19 11 0,000 0,06347994 0,10397055 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06347994 0,10389982 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06361403 0,10404851 ! urogenital system development GO:0001655 137 69 1,000 0,06361403 0,10397783 ! glycerolipid biosynthetic process GO:0045017 118 69 1,000 0,06361403 0,10390724 ! amine catabolic process GO:0009310 117 71 1,000 0,06687321 0,10915668 ! reproductive structure development GO:0048608 113 71 1,000 0,06687321 0,10908268 ! B cell activation GO:0042113 160 71 1,000 0,06687321 0,10900877 ! acute inflammatory response GO:0002526 113 72 1,000 0,06852331 0,11162295 ! carbohydrate transport GO:0008643 110 72 1,000 0,06852331 0,11154742 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06852331 0,111472 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06904817 0,11224993 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06904817 0,11217414 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06904817 0,11209845 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,06904817 0,11202286 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06904817 0,11194737 ! cartilage condensation GO:0001502 20 12 0,000 0,06904817 0,11187199 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06904817 0,1117967 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06904817 0,11172152 ! protein complex disassembly GO:0043241 27 12 0,000 0,06904817 0,11164644 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06904817 0,11157146 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06904817 0,11149658 ! hippocampus development GO:0021766 26 12 0,000 0,06904817 0,1114218 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06904817 0,11134712 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06904817 0,11127254 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06904817 0,11119806 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06904817 0,11112368 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06904817 0,1110494 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06904817 0,11097522 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06904817 0,11090114 ! drug transport GO:0015893 16 12 0,000 0,06904817 0,11082715 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06904817 0,11075327 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06904817 0,11067948 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06904817 0,11060579 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06904817 0,1105322 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06904817 0,11045871 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06904817 0,11038532 ! forebrain cell migration GO:0021885 21 12 0,000 0,06904817 0,11031202 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06904817 0,11023882 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06904817 0,11016572 ! entry into host cell GO:0030260 32 12 0,000 0,06904817 0,11009271 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,06904817 0,1100198 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06904817 0,10994699 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06904817 0,10987427 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06904817 0,10980165 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06904817 0,10972913 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06904817 0,1096567 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06904817 0,10958437 ! protein homotetramerization GO:0051289 21 12 0,000 0,06904817 0,10951213 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06904817 0,10943999 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06904817 0,10936794 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06904817 0,10929599 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06904817 0,10922413 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06904817 0,10915237 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06904817 0,1090807 ! cranial nerve development GO:0021545 20 12 0,000 0,06904817 0,10900912 ! fucose catabolic process GO:0019317 22 12 0,000 0,06904817 0,10893764 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06904817 0,10886625 ! histone acetylation GO:0016573 26 12 0,000 0,06904817 0,10879496 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06904817 0,10872376 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06904817 0,10865265 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06904817 0,10858163 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06904817 0,10851071 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06904817 0,10843988 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06904817 0,10836915 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06904817 0,1082985 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06904817 0,10822795 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06904817 0,10815749 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,06904817 0,10808712 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06904817 0,10801684 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06904817 0,10794665 ! response to cold GO:0009409 17 12 0,000 0,06904817 0,10787656 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06904817 0,10780655 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06904817 0,10773664 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,0701868 0,10944228 ! axon guidance GO:0007411 139 73 1,000 0,0701868 0,10937139 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,07186345 0,11191162 ! organelle localization GO:0051640 136 74 1,000 0,07186345 0,11183923 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,07355305 0,11439473 ! rhythmic process GO:0048511 128 75 1,000 0,07355305 0,11432083 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,07355305 0,11424703 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07458348 0,1157728 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07458348 0,11569816 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07458348 0,11562361 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07458348 0,11554916 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07458348 0,1154748 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07458348 0,11540054 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07458348 0,11532638 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07458348 0,11525231 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07458348 0,11517834 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07458348 0,11510446 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07458348 0,11503067 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07458348 0,11495698 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07458348 0,11488338 ! methionine metabolic process GO:0006555 27 13 0,000 0,07458348 0,11480988 ! plasma membrane organization GO:0007009 24 13 0,000 0,07458348 0,11473647 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07458348 0,11466316 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07458348 0,11458994 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07458348 0,11451681 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07458348 0,11444378 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07458348 0,11437084 ! response to X-ray GO:0010165 25 13 0,000 0,07458348 0,11429799 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07458348 0,11422524 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07458348 0,11415257 ! exocrine system development GO:0035272 32 13 0,000 0,07458348 0,11408 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07458348 0,11400753 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07458348 0,11393514 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07458348 0,11386285 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07458348 0,11379064 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07458348 0,11371853 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07458348 0,11364651 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07458348 0,11357459 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07458348 0,11350275 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07458348 0,113431 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07458348 0,11335935 ! ribosome assembly GO:0042255 17 13 0,000 0,07458348 0,11328778 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,07458348 0,11321631 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07458348 0,11314492 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07458348 0,11307363 ! chromatin silencing GO:0006342 26 13 0,000 0,07458348 0,11300242 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07458348 0,11293131 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07458348 0,11286028 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07458348 0,11278934 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07458348 0,1127185 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07458348 0,11264774 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07458348 0,11257707 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07458348 0,11250649 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07458348 0,11243599 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07458348 0,11236559 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07458348 0,11229527 ! embryonic placenta development GO:0001892 23 13 0,000 0,07458348 0,11222504 ! insulin secretion GO:0030073 23 13 0,000 0,07458348 0,1121549 ! actin filament polymerization GO:0030041 24 13 0,000 0,07458348 0,11208485 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07458348 0,11201489 ! acrosome reaction GO:0007340 18 13 0,000 0,07458348 0,11194501 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,0752554 0,1128831 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07697028 0,11538349 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,07869749 0,11789923 ! lactation GO:0007595 26 14 0,000 0,08008605 0,11990482 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,08008605 0,11983025 ! reproductive cellular process GO:0048610 20 14 0,000 0,08008605 0,11975578 ! tRNA modification GO:0006400 20 14 0,000 0,08008605 0,11968139 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08008605 0,1196071 ! regulation of S phase GO:0033261 23 14 0,000 0,08008605 0,11953291 ! water transport GO:0006833 21 14 0,000 0,08008605 0,1194588 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08008605 0,11938479 ! non-recombinational repair GO:0000726 25 14 0,000 0,08008605 0,11931086 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08008605 0,11923703 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08008605 0,11916329 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08008605 0,11908964 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08008605 0,11901609 ! palate development GO:0060021 31 14 0,000 0,08008605 0,11894262 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08008605 0,11886924 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08008605 0,11879596 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08008605 0,11872276 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08008605 0,11864966 ! arginine metabolic process GO:0006525 17 14 0,000 0,08008605 0,11857664 ! regulation of heart rate GO:0002027 24 14 0,000 0,08008605 0,11850372 ! organic alcohol transport GO:0015850 29 14 0,000 0,08008605 0,11843088 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08008605 0,11835814 ! embryo implantation GO:0007566 30 14 0,000 0,08008605 0,11828548 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08008605 0,11821291 ! L-amino acid transport GO:0015807 30 14 0,000 0,08008605 0,11814043 ! bone mineralization GO:0030282 17 14 0,000 0,08008605 0,11806804 ! stem cell development GO:0048864 43 14 0,000 0,08008605 0,11799574 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08008605 0,11792353 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08008605 0,1178514 ! cerebellum development GO:0021549 21 14 0,000 0,08008605 0,11777937 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08008605 0,11770742 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08008605 0,11763556 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08008605 0,11756379 ! cofactor transport GO:0051181 26 14 0,000 0,08008605 0,1174921 ! NADP metabolic process GO:0006739 24 14 0,000 0,08008605 0,1174205 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,08008605 0,11734899 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08008605 0,11727757 ! intestinal absorption GO:0050892 25 14 0,000 0,08008605 0,11720623 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08008605 0,11713498 ! oxygen transport GO:0015671 21 14 0,000 0,08008605 0,11706382 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08008605 0,11699274 ! regulation of axon extension GO:0030516 37 14 0,000 0,08008605 0,11692175 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08008605 0,11685085 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,08043682 0,11729151 ! muscle cell differentiation GO:0042692 159 80 1,000 0,08218807 0,11977257 ! T cell activation GO:0042110 168 81 1,000 0,08395104 0,12226768 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08555609 0,12452992 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08555609 0,12445463 ! superoxide anion generation GO:0042554 20 15 0,000 0,08555609 0,12437943 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08555609 0,12430432 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08555609 0,12422931 ! copper ion transport GO:0006825 20 15 0,000 0,08555609 0,12415438 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08555609 0,12407954 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08555609 0,12400479 ! sulfate transport GO:0008272 23 15 0,000 0,08555609 0,12393014 ! response to cAMP GO:0051591 22 15 0,000 0,08555609 0,12385557 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08555609 0,12378109 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08555609 0,12370671 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08555609 0,12363241 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08555609 0,1235582 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08555609 0,12348408 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08555609 0,12341005 ! vesicle coating GO:0006901 33 15 0,000 0,08555609 0,12333611 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08555609 0,12326225 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08555609 0,12318849 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08555609 0,12311481 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08555609 0,12304122 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08555609 0,12296772 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08555609 0,1228943 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08555609 0,12282098 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08555609 0,12274774 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08555609 0,12267459 ! histone deacetylation GO:0016575 20 15 0,000 0,08555609 0,12260152 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08555609 0,12252855 ! tissue regeneration GO:0042246 26 15 0,000 0,08555609 0,12245566 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08555609 0,12238285 ! water homeostasis GO:0030104 27 15 0,000 0,08555609 0,12231014 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08555609 0,12223751 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08555609 0,12216496 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08555609 0,1220925 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08555609 0,12202013 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08555609 0,12194784 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08555609 0,12187564 ! cell killing GO:0001906 29 15 0,000 0,08555609 0,12180353 ! detection of bacterium GO:0016045 18 15 0,000 0,08555609 0,1217315 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08555609 0,12165955 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08555609 0,12158769 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08555609 0,12151591 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08555609 0,12144422 ! peptide hormone processing GO:0016486 23 15 0,000 0,08555609 0,12137262 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,08572553 0,12154132 ! response to nutrient GO:0007584 125 82 1,000 0,08572553 0,12146974 ! negative regulation of transport GO:0051051 153 84 1,000 0,08930827 0,12647186 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09099379 0,12878297 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09099379 0,12870726 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09099379 0,12863164 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09099379 0,12855611 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09099379 0,12848066 ! bone remodeling GO:0046849 27 16 0,000 0,09099379 0,12840531 ! filopodium assembly GO:0046847 32 16 0,000 0,09099379 0,12833004 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,09099379 0,12825486 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09099379 0,12817977 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09099379 0,12810477 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09099379 0,12802985 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09099379 0,12795503 ! startle response GO:0001964 28 16 0,000 0,09099379 0,12788029 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09099379 0,12780563 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09099379 0,12773107 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09099379 0,12765659 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09099379 0,1275822 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09099379 0,12750789 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09099379 0,12743367 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09099379 0,12735954 ! response to osmotic stress GO:0006970 25 16 0,000 0,09099379 0,12728549 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09099379 0,12721153 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09099379 0,12713766 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09099379 0,12706387 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09099379 0,12699017 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09099379 0,12691655 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09099379 0,12684302 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09099379 0,12676957 ! axon cargo transport GO:0008088 43 16 0,000 0,09099379 0,12669621 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09099379 0,12662293 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09099379 0,12654974 ! DNA replication initiation GO:0006270 27 16 0,000 0,09099379 0,12647663 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09099379 0,12640361 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09099379 0,12633067 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09099379 0,12625781 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09099379 0,12618504 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09099379 0,12611236 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09099379 0,12603975 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09099379 0,12596723 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09099379 0,1258948 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09099379 0,12582244 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,09099379 0,12575017 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09099379 0,12567799 ! nucleosome assembly GO:0006334 122 85 1,000 0,09111613 0,12577476 ! chromatin assembly GO:0031497 124 86 1,000 0,09293473 0,12821156 ! tube morphogenesis GO:0035239 176 86 1,000 0,09293473 0,12813809 ! alcohol catabolic process GO:0046164 130 86 1,000 0,09293473 0,1280647 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,09476389 0,13051054 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09639933 0,13268694 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09639933 0,13261108 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09639933 0,1325353 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09639933 0,13245961 ! signal complex assembly GO:0007172 41 17 0,000 0,09639933 0,132384 ! endothelial cell migration GO:0043542 28 17 0,000 0,09639933 0,13230849 ! inositol metabolic process GO:0006020 28 17 0,000 0,09639933 0,13223305 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09639933 0,13215771 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09639933 0,13208245 ! glial cell development GO:0021782 27 17 0,000 0,09639933 0,13200727 ! limbic system development GO:0021761 36 17 0,000 0,09639933 0,13193218 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09639933 0,13185718 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09639933 0,13178226 ! heart looping GO:0001947 30 17 0,000 0,09639933 0,13170743 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09639933 0,13163268 ! myoblast differentiation GO:0045445 45 17 0,000 0,09639933 0,13155801 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09639933 0,13148343 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09639933 0,13140894 ! glycine metabolic process GO:0006544 28 17 0,000 0,09639933 0,13133453 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09639933 0,1312602 ! NAD metabolic process GO:0019674 29 17 0,000 0,09639933 0,13118596 ! membrane budding GO:0006900 37 17 0,000 0,09639933 0,1311118 ! DNA integration GO:0015074 29 17 0,000 0,09639933 0,13103773 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,09639933 0,13096374 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09639933 0,13088983 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09639933 0,130816 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09639933 0,13074226 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09639933 0,13066861 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09639933 0,13059503 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,09639933 0,13052154 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09639933 0,13044813 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09639933 0,1303748 ! steroid catabolic process GO:0006706 31 17 0,000 0,09639933 0,13030156 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09639933 0,1302284 ! gas transport GO:0015669 25 17 0,000 0,09639933 0,13015532 ! organic cation transport GO:0015695 31 17 0,000 0,09639933 0,13008232 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09639933 0,1300094 ! microspike assembly GO:0030035 36 17 0,000 0,09639933 0,12993657 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09639933 0,12986382 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09639933 0,12979115 ! ATP biosynthetic process GO:0006754 159 88 1,000 0,09660341 0,12999317 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,0984531 0,13240814 ! ossification GO:0001503 188 90 1,000 0,10031279 0,13483383 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,10031279 0,13475855 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,1017729 0,13664374 ! neuron maturation GO:0042551 42 18 0,000 0,1017729 0,13656754 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,1017729 0,13649141 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,1017729 0,13641537 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,1017729 0,13633942 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,1017729 0,13626355 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,1017729 0,13618776 ! memory GO:0007613 31 18 0,000 0,1017729 0,13611206 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,1017729 0,13603644 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,1017729 0,13596091 ! patterning of blood vessels GO:0001569 39 18 0,000 0,1017729 0,13588546 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,1017729 0,13581009 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,1017729 0,13573481 ! glutamine metabolic process GO:0006541 29 18 0,000 0,1017729 0,13565961 ! response to retinoic acid GO:0032526 26 18 0,000 0,1017729 0,13558449 ! response to fungus GO:0009620 21 18 0,000 0,1017729 0,13550946 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,1017729 0,13543451 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,1017729 0,13535964 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,1017729 0,13528486 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,1017729 0,13521016 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,1017729 0,13513554 ! vitamin transport GO:0051180 27 18 0,000 0,1017729 0,135061 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,1017729 0,13498654 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,1017729 0,13491217 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,1017729 0,13483788 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,1017729 0,13476367 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,1017729 0,13468954 ! nerve development GO:0021675 28 18 0,000 0,1017729 0,1346155 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,1017729 0,13454153 ! bone development GO:0060348 189 91 1,000 0,10218228 0,13500855 ! sterol metabolic process GO:0016125 152 91 1,000 0,10218228 0,13493445 ! response to protein stimulus GO:0051789 149 91 1,000 0,10218228 0,13486043 ! nucleosome organization GO:0034728 138 92 1,000 0,10406141 0,13726521 ! phospholipid biosynthetic process GO:0008654 167 92 1,000 0,10406141 0,13719 ! protein secretion GO:0009306 39 19 0,000 0,10711469 0,14113798 ! positive regulation of translation GO:0045727 30 19 0,000 0,10711469 0,14106073 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10711469 0,14098356 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10711469 0,14090648 ! skin development GO:0043588 36 19 0,000 0,10711469 0,14082948 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10711469 0,14075257 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10711469 0,14067574 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10711469 0,14059899 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10711469 0,14052233 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10711469 0,14044575 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10711469 0,14036925 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,10711469 0,14029284 ! cerebral cortex development GO:0021987 36 19 0,000 0,10711469 0,14021651 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10711469 0,14014026 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10711469 0,1400641 ! heme metabolic process GO:0042168 36 19 0,000 0,10711469 0,13998802 ! neuromuscular junction development GO:0007528 34 19 0,000 0,10711469 0,13991202 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10711469 0,13983611 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10711469 0,13976027 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10711469 0,13968452 ! peptide cross-linking GO:0018149 37 19 0,000 0,10711469 0,13960886 ! protein export from nucleus GO:0006611 36 19 0,000 0,10711469 0,13953327 ! heart process GO:0003015 30 19 0,000 0,10711469 0,13945776 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10711469 0,13938234 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10711469 0,139307 ! visual learning GO:0008542 36 19 0,000 0,10711469 0,13923174 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10711469 0,13915656 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10711469 0,13908146 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10711469 0,13900644 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10711469 0,13893151 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10711469 0,13885665 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10711469 0,13878188 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10711469 0,13870718 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10711469 0,13863257 ! cilium assembly GO:0042384 37 19 0,000 0,10711469 0,13855804 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10711469 0,13848358 ! female pregnancy GO:0007565 164 94 1,000 0,10784783 0,13935654 ! leukocyte differentiation GO:0002521 202 96 1,000 0,11167065 0,14421878 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 0,11167065 0,14414141 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 1,000 0,11167065 0,14406412 ! detection of stimulus GO:0051606 151 96 1,000 0,11167065 0,14398692 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11242489 0,14488179 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,11242489 0,14480423 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11242489 0,14472675 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11242489 0,14464935 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11242489 0,14457204 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,11242489 0,14449481 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11242489 0,14441767 ! response to vitamin GO:0033273 31 20 0,000 0,11242489 0,1443406 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11242489 0,14426362 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11242489 0,14418672 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11242489 0,14410991 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11242489 0,14403317 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11242489 0,14395652 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11242489 0,14387994 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11242489 0,14380345 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11242489 0,14372704 ! body fluid secretion GO:0007589 31 20 0,000 0,11242489 0,14365071 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11242489 0,14357447 ! peptide secretion GO:0002790 35 20 0,000 0,11242489 0,1434983 ! stem cell differentiation GO:0048863 53 20 0,000 0,11242489 0,14342221 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11242489 0,14334621 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11242489 0,14327028 ! sensory perception of pain GO:0019233 30 20 0,000 0,11242489 0,14319444 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11242489 0,14311867 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11242489 0,14304299 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11242489 0,14296739 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11242489 0,14289186 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11242489 0,14281642 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11242489 0,14274105 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11242489 0,14266577 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11242489 0,14259056 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11242489 0,14251543 ! regulation of glucose import GO:0046324 29 20 0,000 0,11242489 0,14244039 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11242489 0,14236542 ! actin filament-based movement GO:0030048 43 20 0,000 0,11242489 0,14229053 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,11242489 0,14221572 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11242489 0,14214098 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11242489 0,14206633 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11242489 0,14199176 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,11359527 0,14339466 ! response to virus GO:0009615 160 98 1,000 0,11552848 0,14575853 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,11552848 0,14568214 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,11552848 0,14560583 GO:0016054|organic acid catabolic process, ! regulation of cell killing GO:0031341 42 21 0,000 0,11770369 0,14826967 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11770369 0,14819209 ! hormone secretion GO:0046879 38 21 0,000 0,11770369 0,14811458 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11770369 0,14803716 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11770369 0,14795981 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11770369 0,14788255 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11770369 0,14780536 ! axis specification GO:0009798 38 21 0,000 0,11770369 0,14772826 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11770369 0,14765124 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11770369 0,1475743 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11770369 0,14749744 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11770369 0,14742066 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11770369 0,14734395 ! cytolysis GO:0019835 24 21 0,000 0,11770369 0,14726733 ! vasodilation GO:0042311 39 21 0,000 0,11770369 0,14719079 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11770369 0,14711433 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11770369 0,14703794 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,11770369 0,14696164 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,11770369 0,14688541 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11770369 0,14680927 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11770369 0,1467332 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11770369 0,14665721 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11770369 0,1465813 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11770369 0,14650547 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11770369 0,14642972 ! collagen catabolic process GO:0030574 28 21 0,000 0,11770369 0,14635405 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11770369 0,14627845 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12295127 0,15272109 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12295127 0,15264228 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12295127 0,15256356 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12295127 0,15248492 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12295127 0,15240636 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,12295127 0,15232788 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12295127 0,15224948 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12295127 0,15217117 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12295127 0,15209293 ! sensory perception of taste GO:0050909 28 22 0,000 0,12295127 0,15201477 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,12295127 0,1519367 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12295127 0,1518587 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12295127 0,15178078 ! vacuolar transport GO:0007034 36 22 0,000 0,12295127 0,15170295 ! lysosome organization GO:0007040 41 22 0,000 0,12295127 0,15162519 ! fucose metabolic process GO:0006004 39 22 0,000 0,12295127 0,15154751 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12295127 0,15146992 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12295127 0,1513924 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12295127 0,15131496 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12295127 0,1512376 ! sarcomere organization GO:0045214 30 22 0,000 0,12295127 0,15116032 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,12295127 0,15108312 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12295127 0,151006 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12295127 0,15092895 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12295127 0,15085199 ! protein stabilization GO:0050821 39 22 0,000 0,12295127 0,1507751 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,1281678 0,15709207 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,1281678 0,15701209 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1281678 0,15693218 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1281678 0,15685236 ! gluconeogenesis GO:0006094 33 23 0,000 0,1281678 0,15677262 ! viral genome replication GO:0019079 41 23 0,000 0,1281678 0,15669296 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1281678 0,15661338 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1281678 0,15653388 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,1281678 0,15645446 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1281678 0,15637512 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1281678 0,15629586 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1281678 0,15621669 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,1281678 0,15613759 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1281678 0,15605857 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1281678 0,15597963 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,1281678 0,15590078 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1281678 0,155822 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,1281678 0,1557433 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1281678 0,15566468 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1281678 0,15558614 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1281678 0,15550768 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1281678 0,1554293 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1281678 0,155351 ! fatty acid transport GO:0015908 44 23 0,000 0,1281678 0,15527278 ! platelet activation GO:0030168 37 23 0,000 0,1281678 0,15519463 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1281678 0,15511657 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1281678 0,15503858 ! hormone transport GO:0009914 40 23 0,000 0,1281678 0,15496067 ! cell-cell recognition GO:0009988 25 23 0,000 0,1281678 0,15488284 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1281678 0,15480509 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1281678 0,15472741 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,1281678 0,15464982 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1281678 0,1545723 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1281678 0,15449486 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,13335349 0,16066524 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13335349 0,16058483 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13335349 0,1605045 ! spinal cord development GO:0021510 47 24 0,000 0,13335349 0,16042425 ! vacuole organization GO:0007033 43 24 0,000 0,13335349 0,16034407 ! digestive system process GO:0022600 39 24 0,000 0,13335349 0,16026398 ! regulation of behavior GO:0050795 43 24 0,000 0,13335349 0,16018397 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13335349 0,16010404 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13335349 0,16002419 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,13335349 0,15994441 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13335349 0,15986472 ! pallium development GO:0021543 49 24 0,000 0,13335349 0,15978511 ! pentose metabolic process GO:0019321 35 24 0,000 0,13335349 0,15970557 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,13335349 0,15962612 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13335349 0,15954674 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13335349 0,15946744 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13335349 0,15938822 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13335349 0,15930908 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13335349 0,15923002 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13335349 0,15915104 ! regulation of amine transport GO:0051952 40 24 0,000 0,13335349 0,15907213 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,1385085 0,16513947 ! myelination GO:0042552 45 25 0,000 0,1385085 0,16505768 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,1385085 0,16497596 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,1385085 0,16489433 ! phototransduction GO:0007602 33 25 0,000 0,1385085 0,16481278 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,1385085 0,16473131 ! sperm motility GO:0030317 31 25 0,000 0,1385085 0,16464992 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,1385085 0,16456862 ! receptor metabolic process GO:0043112 46 25 0,000 0,1385085 0,16448739 ! chromosome condensation GO:0030261 45 25 0,000 0,1385085 0,16440624 ! neural crest cell development GO:0014032 54 25 0,000 0,1385085 0,16432517 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,1385085 0,16424418 ! negative regulation of cell development GO:0010721 73 25 0,000 0,1385085 0,16416327 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,1385085 0,16408245 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,1385085 0,1640017 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,1385085 0,16392103 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,1385085 0,16384044 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,1385085 0,16375992 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,1385085 0,16367949 ! immunoglobulin production GO:0002377 55 25 0,000 0,1385085 0,16359914 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,1385085 0,16351886 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,1385085 0,16343867 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,1385085 0,16335855 ! telomere organization GO:0032200 43 25 0,000 0,1385085 0,16327851 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,1385085 0,16319855 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14363302 0,16915371 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14363302 0,16907096 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14363302 0,16898828 ! initiation of viral infection GO:0019059 57 26 0,000 0,14363302 0,16890569 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14363302 0,16882317 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14363302 0,16874074 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14363302 0,16865839 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14363302 0,16857611 ! tube lumen formation GO:0035148 50 26 0,000 0,14363302 0,16849392 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14363302 0,16841181 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14363302 0,16832978 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,14363302 0,16824783 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14363302 0,16816595 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14363302 0,16808416 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14363302 0,16800245 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14363302 0,16792081 ! blastocyst development GO:0001824 49 26 0,000 0,14363302 0,16783926 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14363302 0,16775778 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14363302 0,16767639 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,14872722 0,17353913 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14872722 0,17345501 ! iron ion transport GO:0006826 59 27 0,000 0,14872722 0,17337097 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,14872722 0,17328702 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14872722 0,17320314 ! protein amino acid acylation GO:0043543 55 27 0,000 0,14872722 0,17311935 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14872722 0,17303563 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14872722 0,172952 ! fat cell differentiation GO:0045444 50 27 0,000 0,14872722 0,17286845 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14872722 0,17278498 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14872722 0,17270159 ! autophagy GO:0006914 41 27 0,000 0,14872722 0,17261828 ! primary neural tube formation GO:0014020 51 27 0,000 0,14872722 0,17253505 ! base-excision repair GO:0006284 41 27 0,000 0,14872722 0,1724519 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14872722 0,17236883 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14872722 0,17228584 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14872722 0,17220293 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14872722 0,1721201 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14872722 0,17203735 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,14872722 0,17195468 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15379129 0,17772423 ! circadian rhythm GO:0007623 50 28 0,000 0,15379129 0,17763891 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15379129 0,17755367 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,15379129 0,17746851 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,15379129 0,17738343 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15379129 0,17729844 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15379129 0,17721352 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15379129 0,17712869 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15379129 0,17704394 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15379129 0,17695927 ! synaptogenesis GO:0007416 42 28 0,000 0,15379129 0,17687468 ! lipid oxidation GO:0034440 43 28 0,000 0,15379129 0,17679018 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15379129 0,17670575 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15379129 0,1766214 ! translational initiation GO:0006413 65 29 0,000 0,1588254 0,1823158 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,1588254 0,18222886 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,1588254 0,182142 ! regulation of pH GO:0006885 43 29 0,000 0,1588254 0,18205522 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,1588254 0,18196853 ! catechol metabolic process GO:0009712 54 29 0,000 0,1588254 0,18188192 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,1588254 0,18179539 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,1588254 0,18170894 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,1588254 0,18162258 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,1588254 0,1815363 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,1588254 0,1814501 ! detection of light stimulus GO:0009583 38 29 0,000 0,1588254 0,18136398 ! phenol metabolic process GO:0018958 55 30 0,000 0,16382973 0,18698972 ! zinc ion transport GO:0006829 45 30 0,000 0,16382973 0,18690106 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16382973 0,18681248 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16382973 0,18672398 ! acute-phase response GO:0006953 49 30 0,000 0,16382973 0,18663557 ! myofibril assembly GO:0030239 47 30 0,000 0,16382973 0,18654724 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16382973 0,186459 ! phospholipid transport GO:0015914 51 30 0,000 0,16382973 0,18637084 ! ensheathment of neurons GO:0007272 57 30 0,000 0,16382973 0,18628276 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16382973 0,18619477 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16382973 0,18610686 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,16382973 0,18601903 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16382973 0,18593129 ! eye morphogenesis GO:0048592 60 30 0,000 0,16382973 0,18584362 ! regulation of B cell activation GO:0050864 50 30 0,000 0,16382973 0,18575604 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16880445 0,19130641 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16880445 0,19121634 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16880445 0,19112636 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16880445 0,19103646 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16880445 0,19094664 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16880445 0,19085691 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16880445 0,19076727 ! peptide transport GO:0015833 55 31 0,000 0,16880445 0,1906777 ! natural killer cell activation GO:0030101 45 31 0,000 0,16880445 0,19058823 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16880445 0,19049883 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16880445 0,19040952 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16880445 0,19032029 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,16880445 0,19023115 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16880445 0,19014209 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,17374974 0,19562091 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17374974 0,19552941 ! spliceosome assembly GO:0000245 67 32 0,000 0,17374974 0,195438 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17374974 0,19534667 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17374974 0,19525543 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17374974 0,19516427 ! muscle cell development GO:0055001 49 32 0,000 0,17374974 0,1950732 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17374974 0,19498222 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17374974 0,19489132 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,17374974 0,1948005 ! peripheral nervous system development GO:0007422 64 32 0,000 0,17374974 0,19470977 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,17374974 0,19461912 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17374974 0,19452856 ! gene silencing GO:0016458 65 32 0,000 0,17374974 0,19443808 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,17866577 0,19984651 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17866577 0,19975365 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17866577 0,19966087 ! cell fate specification GO:0001708 52 33 0,000 0,17866577 0,19956817 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17866577 0,19947557 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,17866577 0,19938305 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17866577 0,19929061 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,18355272 0,20464682 ! glial cell differentiation GO:0010001 63 34 0,000 0,18355272 0,20455203 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18355272 0,20445733 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,18355272 0,20436272 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,18355272 0,20426819 ! mismatch repair GO:0006298 46 34 0,000 0,18355272 0,20417376 ! spermatid development GO:0007286 63 34 0,000 0,18355272 0,20407941 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18355272 0,20398514 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,18355272 0,20389097 ! placenta development GO:0001890 53 34 0,000 0,18355272 0,20379688 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,18841074 0,20909421 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18841074 0,20899781 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,18841074 0,2089015 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18841074 0,20880527 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,18841074 0,20870914 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,18841074 0,20861309 ! telencephalon development GO:0021537 68 35 0,000 0,18841074 0,20851713 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18841074 0,20842126 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,18841074 0,20832548 ! neural tube formation GO:0001841 67 35 0,000 0,18841074 0,20822979 ! vesicle localization GO:0051648 64 35 0,000 0,18841074 0,20813418 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,19324003 0,21337104 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19324003 0,21327317 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19324003 0,21317538 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19324003 0,21307768 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,19324003 0,21298008 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19324003 0,21288256 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19324003 0,21278513 ! aerobic respiration GO:0009060 55 36 0,000 0,19324003 0,21268779 ! embryonic organ development GO:0048568 57 36 0,000 0,19324003 0,21259054 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19324003 0,21249338 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,19324003 0,2123963 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19804073 0,21757352 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19804073 0,21747421 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19804073 0,217375 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19804073 0,21727588 ! organic anion transport GO:0015711 68 37 0,000 0,19804073 0,21717685 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19804073 0,21707791 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,19804073 0,21697905 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19804073 0,21688029 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19804073 0,21678162 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,19804073 0,21668304 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,20281303 0,22180371 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20281303 0,22170293 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20281303 0,22160225 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,20281303 0,22150166 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,20281303 0,22140116 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20281303 0,22130075 ! mRNA catabolic process GO:0006402 71 39 0,000 0,20755709 0,22637459 ! learning GO:0007612 77 39 0,000 0,20755709 0,22627202 ! segmentation GO:0035282 67 39 0,000 0,20755709 0,22616954 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20755709 0,22606716 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20755709 0,22596486 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,20755709 0,22586266 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20755709 0,22576056 ! RNA modification GO:0009451 57 39 0,000 0,20755709 0,22565854 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20755709 0,22555662 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21227307 0,23057743 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21227307 0,23047338 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21227307 0,23036942 ! feeding behavior GO:0007631 59 40 0,000 0,21227307 0,23026556 ! negative regulation of binding GO:0051100 72 40 0,000 0,21227307 0,23016179 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21227307 0,23005811 ! maintenance of protein location GO:0045185 91 40 0,000 0,21227307 0,22995453 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21696114 0,23492732 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,21696114 0,23482164 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,21696114 0,23471605 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21696114 0,23461056 ! gliogenesis GO:0042063 88 41 0,000 0,21696114 0,23450517 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21696114 0,23439987 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,21696114 0,23429466 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,21696114 0,23418955 ! polyol metabolic process GO:0019751 66 41 0,000 0,21696114 0,23408453 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,22162146 0,23900549 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,22162146 0,23889841 ! regulation of tube size GO:0035150 71 42 0,000 0,22162146 0,23879142 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22162146 0,23868453 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,22162146 0,23857774 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,22162146 0,23847104 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22162146 0,23836444 ! neuron migration GO:0001764 79 42 0,000 0,22162146 0,23825793 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22162146 0,23815152 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,22625421 0,24302126 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22625421 0,24291282 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22625421 0,24280447 ! neural tube development GO:0021915 77 43 0,000 0,22625421 0,24269622 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,22625421 0,24258807 ! striated muscle contraction GO:0006941 77 43 0,000 0,22625421 0,24248001 ! phagocytosis GO:0006909 90 43 0,000 0,22625421 0,24237205 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22625421 0,24226419 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23085953 0,24708542 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,23085953 0,24697556 ! double-strand break repair GO:0006302 81 44 0,000 0,23085953 0,24686579 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23085953 0,24675612 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,2354376 0,25153768 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,2354376 0,25142604 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,2354376 0,25131449 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,2354376 0,25120304 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,2354376 0,25109169 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,2354376 0,25098044 ! cell growth GO:0016049 84 45 0,000 0,2354376 0,25086929 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23998856 0,25560535 ! endosome transport GO:0016197 108 47 0,000 0,24451259 0,26030854 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,24451259 0,26019341 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,24451259 0,26007838 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24451259 0,25996345 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,24451259 0,25984863 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24451259 0,2597339 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,24900984 0,26439438 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24900984 0,26427776 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24900984 0,26416123 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24900984 0,26404481 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,24900984 0,26392849 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,24900984 0,26381227 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,25348046 0,26843046 ! regulation of ion transport GO:0043269 77 49 0,000 0,25348046 0,26831236 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,25348046 0,26819437 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,25348046 0,26807648 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,25348046 0,2679587 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25348046 0,26784102 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,25792462 0,27241732 ! neuromuscular process GO:0050905 99 50 0,000 0,25792462 0,27229778 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,25792462 0,27217835 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25792462 0,27205903 ! positive regulation of binding GO:0051099 78 51 0,000 0,26234247 0,27659772 ! viral infectious cycle GO:0019058 99 51 0,000 0,26234247 0,27647656 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,26234247 0,27635551 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,26234247 0,27623457 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,26234247 0,27611373 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,26234247 0,275993 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,26234247 0,27587237 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,26234247 0,27575185 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,26673417 0,28024559 ! cartilage development GO:0051216 90 52 0,000 0,26673417 0,28012327 ! synapse organization GO:0050808 85 52 0,000 0,26673417 0,28000105 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,27109986 0,28445978 ! RNA catabolic process GO:0006401 93 53 0,000 0,27109986 0,28433578 ! regulation of translational initiation GO:0006446 82 53 0,000 0,27109986 0,28421188 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,27109986 0,2840881 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,27109986 0,28396442 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,27543971 0,28838466 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,27543971 0,28825922 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,27543971 0,28813389 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,27543971 0,28800867 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27543971 0,28788355 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27543971 0,28775855 ! chloride transport GO:0006821 90 55 0,000 0,27975386 0,2921388 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27975386 0,29201205 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,27975386 0,29188542 ! regulation of actin filament length GO:0030832 105 56 0,000 0,28404246 0,29623154 ! sensory perception of smell GO:0007608 80 56 0,000 0,28404246 0,29610319 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,28404246 0,29597495 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28404246 0,29584683 ! proton transport GO:0015992 94 56 0,000 0,28404246 0,29571881 ! muscle fiber development GO:0048747 112 57 0,000 0,28830568 0,30002745 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,28830568 0,29989773 ! hydrogen transport GO:0006818 97 58 0,000 0,29254364 0,30417459 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,29254364 0,3040432 ! positive regulation of secretion GO:0051047 95 59 0,000 0,29675651 0,3082885 ! regulation of cellular component size GO:0032535 109 59 0,000 0,29675651 0,30815545 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,29675651 0,30802251 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,29675651 0,30788968 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,30094444 0,31210014 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,30094444 0,31196567 ! camera-type eye development GO:0043010 116 60 0,000 0,30094444 0,31183132 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30510756 0,31600895 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30924602 0,32015746 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,31335998 0,32427704 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31744957 0,32836787 ! single fertilization GO:0007338 75 64 0,000 0,31744957 0,32822676 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32151494 0,33228735 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,32151494 0,33214467 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,32555623 0,33617523 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,32555623 0,33603101 ! cell projection assembly GO:0030031 120 66 0,000 0,32555623 0,33588692 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,32957358 0,339886 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,32957358 0,33974038 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,32957358 0,33959488 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,32957358 0,3394495 ! amino acid transport GO:0006865 125 68 0,000 0,33356714 0,34341572 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33356714 0,34326883 ! regulation of lipase activity GO:0060191 130 68 0,000 0,33356714 0,34312207 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,33753704 0,34705731 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,33753704 0,34690906 ! antigen processing and presentation GO:0019882 104 69 0,000 0,33753704 0,34676093 ! appendage morphogenesis GO:0035107 135 70 0,000 0,34148342 0,35066543 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 0,000 0,34540642 0,3545426 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 0,000 0,34540642 0,35439141 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,34930618 0,35823984 ! learning or memory GO:0007611 147 73 0,000 0,35318284 0,36206132 ! regulation of blood pressure GO:0008217 125 73 0,000 0,35318284 0,36190712 ! fertilization GO:0009566 90 73 0,000 0,35318284 0,36175305 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,35703653 0,36554463 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,35703653 0,36538915 ! neurotransmitter transport GO:0006836 123 74 0,000 0,35703653 0,3652338 ! exocytosis GO:0006887 133 74 0,000 0,35703653 0,36507858 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,35703653 0,36492349 ! eye development GO:0001654 143 74 0,000 0,35703653 0,36476853 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36086739 0,36852586 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,36467555 0,37225684 ! defense response to bacterium GO:0042742 89 76 0,000 0,36467555 0,37209897 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,36467555 0,37194123 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36846114 0,37564301 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,36846114 0,37548391 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,36846114 0,37532494 ! blood coagulation GO:0007596 146 78 0,000 0,37222431 0,37899775 GO:0050817|coagulation, ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37596517 0,38264476 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,37596517 0,38248296 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,37596517 0,3823213 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,37596517 0,38215978 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,37968387 0,38577677 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,37968387 0,38561393 ! protein import into nucleus GO:0006606 158 80 0,000 0,37968387 0,38545122 ! inorganic anion transport GO:0015698 138 80 0,000 0,37968387 0,38528865 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,38338053 0,38887587 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,38338053 0,38871199 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,38338053 0,38854825 ! nuclear import GO:0051170 161 81 0,000 0,38338053 0,38838466 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,38705528 0,39194235 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,38705528 0,39177746 ! regulation of lyase activity GO:0051339 160 83 0,000 0,39070826 0,39530869 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,39433958 0,39881506 ! hemostasis GO:0007599 158 84 0,000 0,39433958 0,3986475 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,39433958 0,39848007 ! response to unfolded protein GO:0006986 131 85 0,000 0,39794939 0,40195895 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,39794939 0,40179027 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,40153779 0,40524326 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,40153779 0,40507335 ! amine transport GO:0015837 155 86 0,000 0,40153779 0,40490358 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,40510493 0,40832948 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 0,000 0,40510493 0,40815849 ! cellular respiration GO:0045333 135 88 0,000 0,40865093 0,41155887 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,40865093 0,41138667 ! regulation of DNA binding GO:0051101 155 88 0,000 0,40865093 0,41121461 ! regulation of neurological system process GO:0031644 148 88 0,000 0,40865093 0,4110427 ! cellular defense response GO:0006968 114 89 0,000 0,4121759 0,41441505 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,4121759 0,41424195 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,41567998 0,41758916 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41916329 0,42091272 ! vitamin metabolic process GO:0006766 139 92 0,000 0,42262595 0,42421278 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,42606808 0,42748949 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,42606808 0,4273113 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,4294898 0,43056353 ! regulation of T cell activation GO:0050863 158 94 0,000 0,4294898 0,4303842 ! mRNA transport GO:0051028 169 96 0,000 0,43627251 0,43699902 ! protein ubiquitination GO:0016567 217 97 0,000 0,43963373 0,44018258 ! hormone metabolic process GO:0042445 157 97 0,000 0,43963373 0,43999948 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,4462965 0,44648207 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,4462965 0,4462965