pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1245-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin receptor signaling pathway GO:0008286 66 27 4,000 4,319E-07 1,055E-03 ! gland morphogenesis GO:0022612 31 13 3,000 7,234E-07 8,836E-04 ! release of cytochrome c from mitochondria GO:0001836 31 14 3,000 1,008E-06 8,21E-04 ! positive regulation of vasoconstriction GO:0045907 10 5 2,000 1,847E-06 1,128E-03 ! response to peptide hormone stimulus GO:0043434 129 64 5,000 1,887E-06 9,219E-04 ! positive regulation of cell motion GO:0051272 157 65 5,000 2,069E-06 8,424E-04 ! cellular response to insulin stimulus GO:0032869 85 38 4,000 2,551E-06 8,904E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 4,75E-06 1,45E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 5,841E-06 1,585E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 6,411E-06 1,566E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 2,000 6,411E-06 1,424E-03 ! protein oligomerization GO:0051259 149 79 5,000 6,513E-06 1,326E-03 ! cellular response to starvation GO:0009267 37 22 3,000 7,107E-06 1,336E-03 ! response to insulin stimulus GO:0032868 98 47 4,000 7,476E-06 1,305E-03 ! regulation of peptidase activity GO:0052547 150 82 5,000 8,089E-06 1,317E-03 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 9,959E-06 1,521E-03 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 1,021E-05 1,468E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,021E-05 1,386E-03 ! gas homeostasis GO:0033483 14 8 2,000 1,021E-05 1,313E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 2,000 1,021E-05 1,248E-03 ! regulation of microtubule polymerization GO:0031113 17 8 2,000 1,021E-05 1,188E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 3,000 1,427E-05 1,584E-03 ! gland development GO:0048732 220 91 5,000 1,475E-05 1,567E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 2,000 1,526E-05 1,553E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,526E-05 1,491E-03 ! response to starvation GO:0042594 47 27 3,000 1,667E-05 1,566E-03 ! cellular response to nutrient levels GO:0031669 45 27 3,000 1,667E-05 1,508E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 3,000 1,936E-05 1,689E-03 ! positive regulation of cell migration GO:0030335 137 58 4,000 2,122E-05 1,787E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 2,17E-05 1,767E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 3,000 2,936E-05 2,314E-03 ! cholesterol homeostasis GO:0042632 60 33 3,000 3,784E-05 2,889E-03 GO:0055092|sterol homeostasis, ! focal adhesion formation GO:0048041 37 12 2,000 3,945E-05 2,92E-03 ! ear development GO:0043583 114 66 4,000 3,987E-05 2,865E-03 ! regulation of lipid metabolic process GO:0019216 132 66 4,000 3,987E-05 2,783E-03 ! chromosome segregation GO:0007059 127 67 4,000 4,289E-05 2,911E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 4,945E-05 3,265E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 5,301E-05 3,408E-03 ! mitotic sister chromatid segregation GO:0000070 63 36 3,000 5,374E-05 3,366E-03 ! cell cycle checkpoint GO:0000075 145 71 4,000 5,676E-05 3,467E-03 ! sister chromatid segregation GO:0000819 65 37 3,000 5,998E-05 3,574E-03 ! lipid localization GO:0010876 32 14 2,000 6,472E-05 3,765E-03 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 2,000 6,472E-05 3,677E-03 ! meiosis I GO:0007127 74 38 3,000 6,674E-05 3,706E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 6,925E-05 3,76E-03 ! regulation of vasodilation GO:0042312 27 15 2,000 8,056E-05 4,278E-03 ! mammary gland development GO:0030879 93 40 3,000 8,189E-05 4,257E-03 ! lipid homeostasis GO:0055088 75 40 3,000 8,189E-05 4,168E-03 ! response to hypoxia GO:0001666 178 81 4,000 1,066E-04 5,316E-03 ! negative regulation of cell cycle process GO:0010948 35 17 2,000 1,194E-04 5,833E-03 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 2,000 1,194E-04 5,718E-03 ! response to oxygen levels GO:0070482 183 83 4,000 1,197E-04 5,624E-03 ! pigmentation GO:0043473 103 46 3,000 1,423E-04 6,561E-03 ! positive regulation of protein complex assembly GO:0031334 34 18 2,000 1,426E-04 6,454E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 1,426E-04 6,336E-03 ! mitochondrion organization GO:0007005 159 87 4,000 1,496E-04 6,525E-03 ! protein homooligomerization GO:0051260 84 49 3,000 1,824E-04 7,816E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,976E-04 8,323E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,976E-04 8,182E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,976E-04 8,046E-03 ! actin filament bundle formation GO:0051017 47 20 2,000 1,976E-04 7,914E-03 ! regulation of fatty acid metabolic process GO:0019217 45 20 2,000 1,976E-04 7,786E-03 ! negative regulation of translation GO:0017148 32 20 2,000 1,976E-04 7,663E-03 ! regulation of membrane potential GO:0042391 179 94 4,000 2,151E-04 8,21E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 2,296E-04 8,628E-03 ! regulation of vasoconstriction GO:0019229 40 21 2,000 2,296E-04 8,498E-03 ! vesicle organization GO:0016050 127 53 3,000 2,475E-04 9,026E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 2,612E-04 9,385E-03 ! forebrain development GO:0030900 210 98 4,000 2,612E-04 9,249E-03 ! reciprocal meiotic recombination GO:0007131 44 22 2,000 2,647E-04 9,238E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 2,647E-04 9,108E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 2,647E-04 8,981E-03 ! response to glucocorticoid stimulus GO:0051384 42 22 2,000 2,647E-04 8,858E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 2,647E-04 8,738E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 2,000 2,647E-04 8,622E-03 ! regulation of muscle contraction GO:0006937 94 54 3,000 2,662E-04 8,556E-03 ! positive regulation of DNA replication GO:0045740 44 23 2,000 3,031E-04 9,617E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 3,031E-04 9,494E-03 ! positive regulation of muscle development GO:0048636 15 5 1,000 3,241E-04 0,0100221 GO:0045844|positive regulation of striated muscle development, ! neuron fate determination GO:0048664 7 5 1,000 3,241E-04 9,897E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 3,241E-04 9,775E-03 ! Notch receptor processing GO:0007220 11 5 1,000 3,241E-04 9,655E-03 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 1,000 3,241E-04 9,539E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 3,241E-04 9,426E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,241E-04 9,315E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 3,241E-04 9,206E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 3,241E-04 9,101E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! virus-infected cell apoptosis GO:0006926 7 5 1,000 3,241E-04 8,997E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,241E-04 8,896E-03 ! peptidyl-histidine phosphorylation GO:0018106 10 5 1,000 3,241E-04 8,797E-03 ! cellular glucose homeostasis GO:0001678 6 5 1,000 3,241E-04 8,701E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,241E-04 8,606E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 3,241E-04 8,513E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,241E-04 8,423E-03 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 3,241E-04 8,334E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,241E-04 8,247E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 3,28E-04 8,261E-03 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 3,45E-04 8,599E-03 ! response to corticosteroid stimulus GO:0031960 46 24 2,000 3,45E-04 8,512E-03 ! membrane depolarization GO:0051899 45 24 2,000 3,45E-04 8,427E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 3,45E-04 8,344E-03 ! positive regulation of organelle organization GO:0010638 108 58 3,000 3,507E-04 8,4E-03 ! vasculogenesis GO:0001570 49 25 2,000 3,903E-04 9,258E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 3,903E-04 9,169E-03 ! keratinization GO:0031424 37 25 2,000 3,903E-04 9,082E-03 ! regulation of smooth muscle contraction GO:0006940 48 26 2,000 4,394E-04 0,01012678 ! regulation of cellular ketone metabolic process GO:0010565 51 26 2,000 4,394E-04 0,01003214 ! regulation of blood coagulation GO:0030193 46 26 2,000 4,394E-04 9,939E-03 ! regulation of mitosis GO:0007088 112 63 3,000 4,815E-04 0,01079276 GO:0051783|regulation of nuclear division, ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 4,843E-04 0,01075568 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 4,843E-04 0,01065878 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 4,843E-04 0,01056361 ! 5S class rRNA transcription GO:0042791 13 6 1,000 4,843E-04 0,01047013 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! establishment of spindle localization GO:0051293 16 6 1,000 4,843E-04 0,01037829 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 19 6 1,000 4,843E-04 0,01028804 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 4,843E-04 0,01019935 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 4,843E-04 0,01011218 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 4,922E-04 0,01019091 ! regulation of chromosome organization GO:0033044 49 27 2,000 4,922E-04 0,01010527 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 6,097E-04 0,01241333 ! negative regulation of neuron differentiation GO:0045665 46 29 2,000 6,097E-04 0,01231074 ! negative regulation of protein kinase cascade GO:0010741 72 30 2,000 6,746E-04 0,01350934 ! regulation of coagulation GO:0050818 52 30 2,000 6,746E-04 0,01339951 ! tRNA transcription GO:0009304 17 7 1,000 6,754E-04 0,01330734 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,754E-04 0,01320088 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,754E-04 0,01309611 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 6,754E-04 0,01299299 ! vesicle fusion GO:0006906 20 7 1,000 6,754E-04 0,01289148 ! organ growth GO:0035265 15 7 1,000 6,754E-04 0,01279155 ! male sex determination GO:0030238 15 7 1,000 6,754E-04 0,01269315 ! spindle checkpoint GO:0031577 16 7 1,000 6,754E-04 0,01259626 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 1,000 6,754E-04 0,01250083 ! B cell lineage commitment GO:0002326 21 7 1,000 6,754E-04 0,01240684 ! T cell lineage commitment GO:0002360 16 7 1,000 6,754E-04 0,01231425 ! peptidyl-histidine modification GO:0018202 17 7 1,000 6,754E-04 0,01222304 ! negative regulation of nuclear division GO:0051784 15 7 1,000 6,754E-04 0,01213316 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 26 7 1,000 6,754E-04 0,0120446 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 6,754E-04 0,01195732 ! protein maturation by peptide bond cleavage GO:0051605 118 70 3,000 7,184E-04 0,01262672 ! cell junction assembly GO:0034329 85 31 2,000 7,438E-04 0,01297887 ! iron ion homeostasis GO:0055072 60 31 2,000 7,438E-04 0,01288682 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 7,438E-04 0,01279607 ! actin filament organization GO:0007015 167 72 3,000 7,989E-04 0,01364904 ! spindle organization GO:0007051 50 32 2,000 8,173E-04 0,01386507 ! hindbrain development GO:0030902 65 32 2,000 8,173E-04 0,01376945 ! positive regulation of catabolic process GO:0009896 72 32 2,000 8,173E-04 0,01367514 ! regulation of caspase activity GO:0043281 136 74 3,000 8,856E-04 0,01471822 ! triglyceride metabolic process GO:0006641 46 33 2,000 8,952E-04 0,01477691 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 1,000 8,972E-04 0,01471026 ! signal peptide processing GO:0006465 12 8 1,000 8,972E-04 0,0146122 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,972E-04 0,01451543 ! pigment granule organization GO:0048753 17 8 1,000 8,972E-04 0,01441993 ! ER overload response GO:0006983 13 8 1,000 8,972E-04 0,01432568 ! regulation of pigmentation during development GO:0048070 25 8 1,000 8,972E-04 0,01423266 ! melanin metabolic process GO:0006582 17 8 1,000 8,972E-04 0,01414083 ! response to UV-B GO:0010224 17 8 1,000 8,972E-04 0,01405019 ! regulation of respiratory burst GO:0060263 12 8 1,000 8,972E-04 0,0139607 ! cholesterol transport GO:0030301 62 34 2,000 9,777E-04 0,0151173 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 9,777E-04 0,01502223 ! cell-matrix adhesion GO:0007160 181 76 3,000 9,787E-04 0,01494394 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 1,028E-03 0,01559523 ! DNA damage checkpoint GO:0000077 78 35 2,000 1,065E-03 0,01605845 ! sterol transport GO:0015918 63 35 2,000 1,065E-03 0,01595994 ! response to steroid hormone stimulus GO:0048545 147 79 3,000 1,131E-03 0,01684741 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,149E-03 0,01701465 ! regulation of glycolysis GO:0006110 20 9 1,000 1,149E-03 0,01691216 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,149E-03 0,01681089 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 1,149E-03 0,01671082 ! negative regulation of endocytosis GO:0045806 12 9 1,000 1,149E-03 0,01661194 ! T cell selection GO:0045058 27 9 1,000 1,149E-03 0,01651422 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 1,149E-03 0,01641765 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,149E-03 0,0163222 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 1,149E-03 0,01622785 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,149E-03 0,01613459 ! branched chain family amino acid catabolic process GO:0009083 19 9 1,000 1,149E-03 0,01604239 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,149E-03 0,01595124 ! positive regulation of cell development GO:0010720 85 36 2,000 1,157E-03 0,01596628 ! meiosis GO:0007126 143 81 3,000 1,241E-03 0,01703569 GO:0051327|M phase of meiotic cell cycle, ! cell junction organization GO:0034330 96 37 2,000 1,254E-03 0,0171087 ! tissue remodeling GO:0048771 78 37 2,000 1,254E-03 0,01701365 ! regulation of microtubule-based process GO:0032886 86 37 2,000 1,254E-03 0,01691966 ! cell-substrate adhesion GO:0031589 189 82 3,000 1,299E-03 0,0174379 ! meiotic cell cycle GO:0051321 144 82 3,000 1,299E-03 0,01734261 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 1,355E-03 0,01799445 ! neutral lipid metabolic process GO:0006638 54 38 2,000 1,355E-03 0,01789718 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 2,000 1,355E-03 0,01780096 ! glycogen metabolic process GO:0005977 63 38 2,000 1,355E-03 0,01770577 ! response to drug GO:0042493 149 83 3,000 1,359E-03 0,01765736 ! regulation of developmental growth GO:0048638 16 10 1,000 1,431E-03 0,01849745 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,431E-03 0,0184001 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 1,431E-03 0,01830376 ! B cell proliferation GO:0042100 19 10 1,000 1,431E-03 0,01820843 ! protein heterooligomerization GO:0051291 17 10 1,000 1,431E-03 0,01811409 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 1,431E-03 0,01802071 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 1,000 1,431E-03 0,0179283 ! response to dsRNA GO:0043331 23 10 1,000 1,431E-03 0,01783683 ! midbrain development GO:0030901 14 10 1,000 1,431E-03 0,01774629 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,431E-03 0,01765666 GO:0043470|regulation of carbohydrate catabolic process, ! response to nicotine GO:0035094 20 10 1,000 1,431E-03 0,01756793 ! carbohydrate homeostasis GO:0033500 59 39 2,000 1,462E-03 0,01785911 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 64 39 2,000 1,462E-03 0,01777026 GO:0006073|cellular glucan metabolic process, ! regulation of neuron differentiation GO:0045664 187 85 3,000 1,484E-03 0,01794693 ! glycerol ether metabolic process GO:0006662 57 40 2,000 1,574E-03 0,01894191 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,742E-03 0,02086657 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,742E-03 0,02076478 ! adult heart development GO:0007512 16 11 1,000 1,742E-03 0,02066398 ! behavioral fear response GO:0001662 27 11 1,000 1,742E-03 0,02056416 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 1,000 1,742E-03 0,02046529 ! alpha-beta T cell activation GO:0046631 26 11 1,000 1,742E-03 0,02036737 ! DNA methylation GO:0006306 19 11 1,000 1,742E-03 0,02027038 GO:0006305|DNA alkylation, ! thymus development GO:0048538 29 11 1,000 1,742E-03 0,02017432 ! oocyte development GO:0048599 20 11 1,000 1,742E-03 0,02007915 ! sequestering of metal ion GO:0051238 15 11 1,000 1,742E-03 0,01998489 ! regulation of embryonic development GO:0045995 35 11 1,000 1,742E-03 0,0198915 ! ear morphogenesis GO:0042471 64 42 2,000 1,814E-03 0,02060683 ! organic ether metabolic process GO:0018904 59 42 2,000 1,814E-03 0,02051143 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 1,814E-03 0,02041691 ! regulation of cell cycle process GO:0010564 161 90 3,000 1,831E-03 0,02052451 ! development of primary male sexual characteristics GO:0046546 80 43 2,000 1,941E-03 0,02165645 ! response to reactive oxygen species GO:0000302 75 44 2,000 2,075E-03 0,02303835 ! energy reserve metabolic process GO:0006112 76 44 2,000 2,075E-03 0,0229341 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 1,000 2,083E-03 0,0229228 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 2,083E-03 0,02282001 ! virus-host interaction GO:0019048 30 12 1,000 2,083E-03 0,02271813 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,083E-03 0,02261716 ! mRNA polyadenylation GO:0006378 24 12 1,000 2,083E-03 0,02251709 ! T cell homeostasis GO:0043029 28 12 1,000 2,083E-03 0,02241789 ! oocyte differentiation GO:0009994 21 12 1,000 2,083E-03 0,02231957 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 2,214E-03 0,02361435 ! keratinocyte differentiation GO:0030216 81 45 2,000 2,214E-03 0,02351168 ! biopolymer methylation GO:0043414 91 45 2,000 2,214E-03 0,0234099 ! negative regulation of multicellular organismal process GO:0051241 174 95 3,000 2,232E-03 0,02350074 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,358E-03 0,02472406 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 2,358E-03 0,0246184 ! positive regulation of protein transport GO:0051222 80 46 2,000 2,358E-03 0,02451364 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 2,407E-03 0,02492145 ! transcription initiation GO:0006352 171 97 3,000 2,407E-03 0,02481629 ! regulation of protein localization GO:0032880 188 97 3,000 2,407E-03 0,02471202 ! organelle fusion GO:0048284 36 13 1,000 2,452E-03 0,02506873 ! endocrine pancreas development GO:0031018 25 13 1,000 2,452E-03 0,02496428 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,452E-03 0,02486069 ! membrane protein proteolysis GO:0033619 33 13 1,000 2,452E-03 0,02475796 GO:0006509|membrane protein ectodomain proteolysis, ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,452E-03 0,02465607 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 2,452E-03 0,02455503 ! histone methylation GO:0016571 29 13 1,000 2,452E-03 0,0244548 ! spleen development GO:0048536 24 13 1,000 2,452E-03 0,02435539 ! digestive tract morphogenesis GO:0048546 31 13 1,000 2,452E-03 0,02425679 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! mRNA 3'-end processing GO:0031124 25 13 1,000 2,452E-03 0,02415898 ! positive regulation of cell cycle GO:0045787 96 48 2,000 2,664E-03 0,02613974 ! regulation of JAK-STAT cascade GO:0046425 76 48 2,000 2,664E-03 0,02603519 ! cellular component disassembly GO:0022411 89 48 2,000 2,664E-03 0,02593146 ! male sex differentiation GO:0046661 93 48 2,000 2,664E-03 0,02582856 ! regulation of inflammatory response GO:0050727 84 48 2,000 2,664E-03 0,02572647 ! JAK-STAT cascade GO:0007259 82 48 2,000 2,664E-03 0,02562518 ! methylation GO:0032259 97 48 2,000 2,664E-03 0,02552469 ! rRNA transcription GO:0009303 28 14 1,000 2,85E-03 0,02720174 ! hair follicle morphogenesis GO:0031069 27 14 1,000 2,85E-03 0,0270959 ! RNA polyadenylation GO:0043631 32 14 1,000 2,85E-03 0,02699087 ! fear response GO:0042596 34 14 1,000 2,85E-03 0,02688666 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 2,85E-03 0,02678325 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 37 14 1,000 2,85E-03 0,02668063 ! response to gamma radiation GO:0010332 30 14 1,000 2,85E-03 0,0265788 ! male genitalia development GO:0030539 26 14 1,000 2,85E-03 0,02647774 ! regulation of RNA stability GO:0043487 33 14 1,000 2,85E-03 0,02637744 ! endocrine system development GO:0035270 109 50 2,000 2,994E-03 0,02760059 ! activation of caspase activity GO:0006919 95 50 2,000 2,994E-03 0,02749683 ! regulation of ossification GO:0030278 123 50 2,000 2,994E-03 0,02739384 ! epidermal cell differentiation GO:0009913 87 50 2,000 2,994E-03 0,02729163 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,277E-03 0,02975724 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 3,277E-03 0,02964703 ! glycoprotein catabolic process GO:0006516 33 15 1,000 3,277E-03 0,02953763 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 3,277E-03 0,02942904 ! muscle maintenance GO:0046716 26 15 1,000 3,277E-03 0,02932124 ! lymphocyte homeostasis GO:0002260 33 15 1,000 3,277E-03 0,02921423 ! response to estrogen stimulus GO:0043627 98 52 2,000 3,348E-03 0,02973876 ! positive regulation of growth GO:0045927 96 53 2,000 3,534E-03 0,0312774 ! inner ear development GO:0048839 89 53 2,000 3,534E-03 0,03116449 ! membrane fusion GO:0006944 122 54 2,000 3,726E-03 0,03274141 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,731E-03 0,03266584 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 3,731E-03 0,03254918 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! pituitary gland development GO:0021983 30 16 1,000 3,731E-03 0,03243335 ! fructose metabolic process GO:0006000 25 16 1,000 3,731E-03 0,03231833 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,731E-03 0,03220413 ! neuron recognition GO:0008038 40 16 1,000 3,731E-03 0,03209074 ! negative regulation of inflammatory response GO:0050728 24 16 1,000 3,731E-03 0,03197814 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 3,731E-03 0,03186633 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 3,924E-03 0,03340404 ! regulation of protein polymerization GO:0032271 117 55 2,000 3,924E-03 0,03328806 ! negative regulation of cell motion GO:0051271 142 55 2,000 3,924E-03 0,03317287 ! regulation of DNA replication GO:0006275 105 56 2,000 4,129E-03 0,03478363 ! metencephalon development GO:0022037 32 17 1,000 4,212E-03 0,03536101 ! auditory receptor cell differentiation GO:0042491 36 17 1,000 4,212E-03 0,03523991 ! regulation of survival gene product expression GO:0045884 38 17 1,000 4,212E-03 0,03511964 ! regulation of protein binding GO:0043393 33 17 1,000 4,212E-03 0,03500018 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 4,212E-03 0,03488154 ! regulation of striated muscle contraction GO:0006942 23 17 1,000 4,212E-03 0,0347637 ! genitalia development GO:0048806 32 17 1,000 4,212E-03 0,03464665 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 4,212E-03 0,03453038 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 4,212E-03 0,0344149 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 4,212E-03 0,03430018 ! RNA 3'-end processing GO:0031123 37 17 1,000 4,212E-03 0,03418623 ! regulation of bone remodeling GO:0046850 143 57 2,000 4,34E-03 0,03510973 ! positive regulation of caspase activity GO:0043280 108 57 2,000 4,34E-03 0,03499386 GO:0010952|positive regulation of peptidase activity, ! regulation of intracellular transport GO:0032386 108 57 2,000 4,34E-03 0,03487875 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 4,558E-03 0,03650739 ! regulation of tissue remodeling GO:0034103 146 58 2,000 4,558E-03 0,03638809 ! adult walking behavior GO:0007628 36 18 1,000 4,721E-03 0,03756596 ! regulation of viral genome replication GO:0045069 30 18 1,000 4,721E-03 0,03744399 ! positive regulation of proteolysis GO:0045862 36 18 1,000 4,721E-03 0,03732281 ! epidermis morphogenesis GO:0048730 43 18 1,000 4,721E-03 0,03720242 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 4,721E-03 0,0370828 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,721E-03 0,03696394 ! defense response to virus GO:0051607 43 18 1,000 4,721E-03 0,03684585 ! DNA catabolic process GO:0006308 94 60 2,000 5,013E-03 0,03899911 ! regulation of endocytosis GO:0030100 104 60 2,000 5,013E-03 0,03887531 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 5,25E-03 0,0405865 ! negative regulation of defense response GO:0031348 27 19 1,000 5,256E-03 0,04050809 ! pigmentation during development GO:0048066 42 19 1,000 5,256E-03 0,0403807 ! cellular pigmentation GO:0033059 37 19 1,000 5,256E-03 0,04025412 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 5,494E-03 0,04194125 ! regulation of homeostatic process GO:0032844 148 62 2,000 5,494E-03 0,04181059 ! regulation of protein complex assembly GO:0043254 132 63 2,000 5,744E-03 0,04358211 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,818E-03 0,04400684 ! transcription from RNA polymerase III promoter GO:0006383 46 20 1,000 5,818E-03 0,04387101 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 5,818E-03 0,04373603 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 40 20 1,000 5,818E-03 0,04360187 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 5,818E-03 0,04346853 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 6,002E-03 0,04470174 ! lipid phosphorylation GO:0046834 43 21 1,000 6,407E-03 0,04757266 ! ovarian follicle development GO:0001541 39 21 1,000 6,407E-03 0,0474285 ! diencephalon development GO:0021536 36 21 1,000 6,407E-03 0,04728521 ! positive regulation of inflammatory response GO:0050729 41 21 1,000 6,407E-03 0,04714279 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 6,407E-03 0,04700122 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 6,537E-03 0,04781304 ! negative regulation of cell growth GO:0030308 142 67 2,000 6,815E-03 0,0496968 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 7,021E-03 0,05104727 ! central nervous system neuron development GO:0021954 47 22 1,000 7,021E-03 0,05089579 ! apoptotic nuclear changes GO:0030262 34 22 1,000 7,021E-03 0,05074521 ! ureteric bud development GO:0001657 50 22 1,000 7,021E-03 0,05059552 ! cell aging GO:0007569 48 22 1,000 7,021E-03 0,05044671 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 7,021E-03 0,05029877 ! renal system process GO:0003014 42 22 1,000 7,021E-03 0,0501517 ! G1 phase GO:0051318 44 22 1,000 7,021E-03 0,05000549 ! response to cytokine stimulus GO:0034097 69 22 1,000 7,021E-03 0,04986012 ! gut development GO:0048565 44 22 1,000 7,021E-03 0,0497156 ! inner ear receptor cell differentiation GO:0060113 42 22 1,000 7,021E-03 0,04957191 ! extracellular matrix organization GO:0030198 146 68 2,000 7,1E-03 0,04998335 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 7,1E-03 0,04983972 ! negative regulation of cell size GO:0045792 144 69 2,000 7,391E-03 0,05173937 ! lung development GO:0030324 165 69 2,000 7,391E-03 0,05159154 ! homeostasis of number of cells GO:0048872 131 69 2,000 7,391E-03 0,05144456 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 7,661E-03 0,05316724 ! regeneration GO:0031099 42 23 1,000 7,661E-03 0,05301663 ! visual behavior GO:0007632 46 23 1,000 7,661E-03 0,05286686 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 7,661E-03 0,05271794 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 1,000 7,661E-03 0,05256986 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 7,661E-03 0,0524226 ! DNA modification GO:0006304 36 23 1,000 7,661E-03 0,05227617 ! respiratory tube development GO:0030323 171 72 2,000 8,309E-03 0,05654199 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 8,309E-03 0,05638493 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 8,309E-03 0,05622874 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 8,326E-03 0,05618677 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 8,326E-03 0,05603198 ! protein amino acid O-linked glycosylation GO:0006493 45 24 1,000 8,326E-03 0,05587805 ! mechanoreceptor differentiation GO:0042490 48 24 1,000 8,326E-03 0,05572496 ! central nervous system neuron differentiation GO:0021953 51 24 1,000 8,326E-03 0,0555727 ! sex determination GO:0007530 48 24 1,000 8,326E-03 0,05542128 ! regulation of viral reproduction GO:0050792 41 24 1,000 8,326E-03 0,05527068 ! oogenesis GO:0048477 44 24 1,000 8,326E-03 0,05512089 ! humoral immune response GO:0006959 115 73 2,000 8,629E-03 0,05697408 ! respiratory system development GO:0060541 175 74 2,000 8,956E-03 0,05897496 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 9,016E-03 0,05920793 ! regulation of transmembrane transport GO:0034762 39 25 1,000 9,016E-03 0,0590492 ! interaction with host GO:0051701 66 25 1,000 9,016E-03 0,05889131 ! lymphocyte proliferation GO:0046651 55 25 1,000 9,016E-03 0,05873427 ! leukocyte homeostasis GO:0001776 50 25 1,000 9,016E-03 0,05857806 ! liver development GO:0001889 55 25 1,000 9,016E-03 0,05842268 ! protein tetramerization GO:0051262 57 25 1,000 9,016E-03 0,05826812 ! molting cycle process GO:0022404 52 26 1,000 9,73E-03 0,06272122 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 1,000 9,73E-03 0,06255616 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 9,73E-03 0,06239197 ! multicellular organismal response to stress GO:0033555 61 26 1,000 9,73E-03 0,06222864 ! osteoblast differentiation GO:0001649 63 26 1,000 9,73E-03 0,06206617 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 9,73E-03 0,06190454 ! response to estradiol stimulus GO:0032355 43 26 1,000 9,73E-03 0,06174375 ! positive regulation of nuclear division GO:0051785 41 26 1,000 9,73E-03 0,06158379 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 9,73E-03 0,06142466 ! phosphoinositide metabolic process GO:0030384 146 77 2,000 9,981E-03 0,06284331 ! regulation of vesicle-mediated transport GO:0060627 136 77 2,000 9,981E-03 0,06268176 ! regulation of catabolic process GO:0009894 173 77 2,000 9,981E-03 0,06252104 ! embryonic pattern specification GO:0009880 49 27 1,000 0,01046944 0,06541393 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 0,01046944 0,06524706 ! mitochondrial membrane organization GO:0007006 60 27 1,000 0,01046944 0,06508104 ! response to toxin GO:0009636 49 27 1,000 0,01046944 0,06491586 ! cellular response to oxidative stress GO:0034599 43 27 1,000 0,01046944 0,06475151 ! leukocyte proliferation GO:0070661 59 27 1,000 0,01046944 0,064588 GO:0032943|mononuclear cell proliferation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,01070033 0,06584612 ! development of primary sexual characteristics GO:0045137 143 80 2,000 0,01107105 0,06795623 ! negative regulation of organelle organization GO:0010639 181 80 2,000 0,01107105 0,06778591 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,01123255 0,06860283 ! neuron fate commitment GO:0048663 52 28 1,000 0,01123255 0,06843175 ! vesicle docking GO:0048278 55 28 1,000 0,01123255 0,06826152 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,01201943 0,0728622 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01201943 0,07268185 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 0,01201943 0,07250239 ! response to metal ion GO:0010038 158 84 2,000 0,01262766 0,0759837 ! regulation of ligase activity GO:0051340 147 84 2,000 0,01262766 0,07579701 ! complement activation, classical pathway GO:0006958 51 30 1,000 0,01282977 0,07682141 ! cell fate determination GO:0001709 64 30 1,000 0,01282977 0,07663358 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01282977 0,07644667 ! tissue homeostasis GO:0001894 50 30 1,000 0,01282977 0,07626067 GO:0048871|multicellular organismal homeostasis, ! cholesterol metabolic process GO:0008203 148 85 2,000 0,01303536 0,07729463 ! negative regulation of growth GO:0045926 168 85 2,000 0,01303536 0,07710747 ! ovulation cycle process GO:0022602 55 31 1,000 0,01366329 0,08062661 ! male gonad development GO:0008584 56 31 1,000 0,01366329 0,08043233 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01366329 0,08023898 ! response to heat GO:0009408 54 31 1,000 0,01366329 0,08004656 ! regulation of protein transport GO:0051223 165 87 2,000 0,01387314 0,08108156 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 2,000 0,01430327 0,08339589 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 0,01451969 0,0844562 ! metanephros development GO:0001656 81 32 1,000 0,01451969 0,0842556 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01451969 0,08405594 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01451969 0,08385722 ! mesoderm formation GO:0001707 73 32 1,000 0,01451969 0,08365945 ! ovulation cycle GO:0042698 57 32 1,000 0,01451969 0,0834626 ! BMP signaling pathway GO:0030509 71 32 1,000 0,01451969 0,08326668 ! response to inorganic substance GO:0010035 173 90 2,000 0,01518605 0,08688411 ! negative regulation of response to external stimulus GO:0032102 50 33 1,000 0,01539869 0,08789486 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01539869 0,08768998 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 0,01539869 0,08748605 ! leukocyte chemotaxis GO:0030595 55 33 1,000 0,01539869 0,08728306 GO:0060326|cell chemotaxis, ! response to hydrogen peroxide GO:0042542 56 34 1,000 0,0163 0,09217802 ! post-embryonic development GO:0009791 76 34 1,000 0,0163 0,09196514 ! inner ear morphogenesis GO:0042472 51 34 1,000 0,0163 0,09175324 ! GPI anchor biosynthetic process GO:0006506 58 34 1,000 0,0163 0,09154231 ! formation of primary germ layer GO:0001704 76 34 1,000 0,0163 0,09133235 ! adult locomotory behavior GO:0008344 62 34 1,000 0,0163 0,09112335 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,0163 0,09091531 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 0,01656677 0,09219274 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01656677 0,09198321 ! sterol metabolic process GO:0016125 166 94 2,000 0,01704214 0,09440802 ! membrane docking GO:0022406 69 35 1,000 0,01722334 0,09519599 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,01722334 0,0949811 ! GPI anchor metabolic process GO:0006505 61 35 1,000 0,01722334 0,09476718 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01722334 0,09455422 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,01722334 0,09434222 ! regulation of defense response GO:0031347 171 95 2,000 0,01752508 0,09578026 ! sex differentiation GO:0007548 171 96 2,000 0,01801562 0,09824142 ! regulation of muscle development GO:0048634 82 36 1,000 0,01816843 0,09885409 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01816843 0,09863441 ! cytokine production GO:0001816 68 36 1,000 0,01816843 0,09841571 ! odontogenesis GO:0042476 74 37 1,000 0,019135 0,10342213 ! female gonad development GO:0008585 71 37 1,000 0,019135 0,10319382 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,019135 0,10296653 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,02005379 0,10767341 GO:0060538|skeletal muscle organ development, ! regulation of protein stability GO:0031647 77 38 1,000 0,02012276 0,10780681 ! pigment metabolic process GO:0042440 87 38 1,000 0,02012276 0,10757091 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,02113145 0,11271643 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,02113145 0,11247086 ! isoprenoid metabolic process GO:0006720 70 39 1,000 0,02113145 0,11222636 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 0,02216079 0,11743775 GO:0006956|complement activation, ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,02216079 0,11718356 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,02216079 0,11693046 ! phosphoinositide biosynthetic process GO:0046489 77 41 1,000 0,02321052 0,12220536 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,02321052 0,12194256 ! mesenchymal cell development GO:0014031 94 41 1,000 0,02321052 0,12168088 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! T cell differentiation GO:0030217 93 42 1,000 0,02428036 0,12701698 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,02428036 0,12674558 ! cytokinesis GO:0000910 84 42 1,000 0,02428036 0,12647533 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,02537007 0,13187039 ! glucose transport GO:0015758 66 43 1,000 0,02537007 0,13159041 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02537007 0,13131162 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02537007 0,13103401 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,02647938 0,13647493 ! hexose transport GO:0008645 68 44 1,000 0,02647938 0,13618761 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,02760802 0,1416941 ! B cell differentiation GO:0030183 124 45 1,000 0,02760802 0,14139705 ! female gamete generation GO:0007292 71 45 1,000 0,02760802 0,14110124 ! developmental growth GO:0048589 88 45 1,000 0,02760802 0,14080666 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02760802 0,14051332 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02837089 0,14409579 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02837089 0,14379684 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02837089 0,14349912 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02837089 0,14320264 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02837089 0,14290737 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02837089 0,14261332 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02837089 0,14232048 ! polyol transport GO:0015791 12 5 0,000 0,02837089 0,14202884 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02837089 0,1417384 ! response to superoxide GO:0000303 10 5 0,000 0,02837089 0,14144913 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02837089 0,14116105 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02837089 0,14087414 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02837089 0,14058839 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02837089 0,1403038 ! female meiosis GO:0007143 10 5 0,000 0,02837089 0,14002036 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02837089 0,13973806 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02837089 0,13945689 ! hypothalamus development GO:0021854 9 5 0,000 0,02837089 0,13917686 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02837089 0,13889795 ! cobalt ion transport GO:0006824 11 5 0,000 0,02837089 0,13862015 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02837089 0,13834346 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02837089 0,13806788 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02837089 0,13779339 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02837089 0,13751999 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02837089 0,13724768 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02837089 0,13697643 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02837089 0,13670626 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02837089 0,13643716 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02837089 0,13616911 ! transposition GO:0032196 9 5 0,000 0,02837089 0,13590211 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02837089 0,13563616 ! negative chemotaxis GO:0050919 16 5 0,000 0,02837089 0,13537124 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02837089 0,13510736 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02837089 0,13484451 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02837089 0,13458267 ! behavioral response to pain GO:0048266 10 5 0,000 0,02837089 0,13432185 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02837089 0,13406204 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02837089 0,13380324 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02837089 0,13354543 ! micturition GO:0060073 9 5 0,000 0,02837089 0,13328861 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02837089 0,13303278 ! copulation GO:0007620 9 5 0,000 0,02837089 0,13277792 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02837089 0,13252405 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02837089 0,13227114 ! bioluminescence GO:0008218 9 5 0,000 0,02837089 0,13201919 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02837089 0,13176821 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02837089 0,13151817 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02837089 0,13126908 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02837089 0,13102094 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02837089 0,13077373 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02837089 0,13052745 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02837089 0,1302821 ! grooming behavior GO:0007625 6 5 0,000 0,02837089 0,13003767 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02837089 0,12979415 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02837089 0,12955154 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02837089 0,12930984 ! response to protozoan GO:0001562 13 5 0,000 0,02837089 0,12906904 ! lymph vessel development GO:0001945 10 5 0,000 0,02837089 0,12882914 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02837089 0,12859012 ! endochondral ossification GO:0001958 17 5 0,000 0,02837089 0,12835199 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02837089 0,12811474 ! single strand break repair GO:0000012 8 5 0,000 0,02837089 0,12787837 ! parathyroid gland development GO:0060017 14 5 0,000 0,02837089 0,12764287 ! anagen GO:0042640 7 5 0,000 0,02837089 0,12740823 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02837089 0,12717445 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02837089 0,12694153 ! cytokine secretion GO:0050663 15 5 0,000 0,02837089 0,12670946 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02837089 0,12647824 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02837089 0,12624786 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02837089 0,12601832 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02837089 0,12578961 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02837089 0,12556173 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02837089 0,12533468 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02837089 0,12510844 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02837089 0,12488302 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02837089 0,12465841 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02837089 0,12443461 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02837089 0,12421161 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02837089 0,1239894 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02837089 0,12376799 ! microvillus organization GO:0032528 8 5 0,000 0,02837089 0,12354737 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02837089 0,12332754 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02837089 0,12310848 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02837089 0,12289021 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02837089 0,1226727 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02837089 0,12245596 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02837089 0,12223999 ! polyol catabolic process GO:0046174 9 5 0,000 0,02837089 0,12202478 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02837089 0,12181033 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02837089 0,12159662 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02837089 0,12138367 ! muscle cell migration GO:0014812 8 5 0,000 0,02837089 0,12117146 ! mitochondrial fission GO:0000266 8 5 0,000 0,02837089 0,12095999 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02837089 0,12074926 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02837089 0,12053926 ! mRNA transcription GO:0009299 10 5 0,000 0,02837089 0,12032999 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02837089 0,12012145 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02837089 0,11991363 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02837089 0,11970652 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02837089 0,11950013 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02837089 0,11929445 ! monocyte activation GO:0042117 10 5 0,000 0,02837089 0,11908948 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02837089 0,11888521 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02837089 0,11868164 ! response to food GO:0032094 6 5 0,000 0,02837089 0,11847876 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02837089 0,11827658 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02837089 0,11807509 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02837089 0,11787428 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02837089 0,11767415 ! forebrain neuron development GO:0021884 13 5 0,000 0,02837089 0,1174747 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02837089 0,11727593 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02837089 0,11707783 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02837089 0,1168804 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02837089 0,11668363 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02837089 0,11648752 ! lipid glycosylation GO:0030259 7 5 0,000 0,02837089 0,11629207 ! nucleobase transport GO:0015851 6 5 0,000 0,02837089 0,11609728 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02837089 0,11590314 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02837089 0,11570964 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02837089 0,11551679 ! basic amino acid transport GO:0015802 12 5 0,000 0,02837089 0,11532459 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02837089 0,11513302 ! actin nucleation GO:0045010 11 5 0,000 0,02837089 0,11494208 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02837089 0,11475178 ! depurination GO:0045007 5 5 0,000 0,02837089 0,11456211 ! depyrimidination GO:0045008 10 5 0,000 0,02837089 0,11437306 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02837089 0,11418464 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02837089 0,11399684 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02837089 0,11380965 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02837089 0,11362308 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02837089 0,11343711 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02837089 0,11325176 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02837089 0,11306701 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02837089 0,11288286 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02837089 0,11269931 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02837089 0,11251636 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02837089 0,112334 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02837089 0,11215223 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02837089 0,11197104 ! response to arsenic GO:0046685 11 5 0,000 0,02837089 0,11179045 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02837089 0,11161043 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02837089 0,11143099 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02837089 0,11125213 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02837089 0,11107384 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02837089 0,11089612 ! response to mercury ion GO:0046689 8 5 0,000 0,02837089 0,11071897 ! response to cadmium ion GO:0046686 7 5 0,000 0,02837089 0,11054239 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02837089 0,11036636 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02837089 0,1101909 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02837089 0,11001599 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02837089 0,10984164 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02837089 0,10966784 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02837089 0,10949459 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02837089 0,10932189 ! decidualization GO:0046697 11 5 0,000 0,02837089 0,10914973 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02837089 0,10897811 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02837089 0,10880703 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02837089 0,10863648 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02837089 0,10846647 ! embryonic cleavage GO:0040016 6 5 0,000 0,02837089 0,10829699 ! peroxisome fission GO:0016559 5 5 0,000 0,02837089 0,10812804 ! histone demethylation GO:0016577 13 5 0,000 0,02837089 0,10795962 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02837089 0,10779172 ! mitotic recombination GO:0006312 9 5 0,000 0,02837089 0,10762434 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02837089 0,10745748 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02837089 0,10729114 ! metaphase plate congression GO:0051310 7 5 0,000 0,02837089 0,10712531 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02837089 0,10695999 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02837089 0,10679519 ! enteric nervous system development GO:0048484 8 5 0,000 0,02837089 0,10663089 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02837089 0,10646709 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02837089 0,1063038 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02837089 0,106141 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02837089 0,10597871 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02837089 0,10581691 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02837089 0,1056556 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02837089 0,10549479 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02837089 0,10533446 ! metaphase GO:0051323 11 5 0,000 0,02837089 0,10517462 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02837089 0,10501527 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02837089 0,10485639 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02837089 0,104698 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02837089 0,10454008 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02837089 0,10438264 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02837089 0,10422568 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02837089 0,10406918 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02837089 0,10391316 ! response to redox state GO:0051775 6 5 0,000 0,02837089 0,1037576 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02837089 0,10360251 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02837089 0,10344787 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02837089 0,1032937 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02837089 0,10313999 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02837089 0,10298674 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02837089 0,10283394 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02837089 0,10268159 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02837089 0,1025297 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02837089 0,10237825 ! striatum development GO:0021756 14 5 0,000 0,02837089 0,10222725 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02837089 0,1020767 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02837089 0,10192658 ! glial cell migration GO:0008347 10 5 0,000 0,02837089 0,10177691 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02837089 0,10162768 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02837089 0,10147888 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02837089 0,10133052 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02837089 0,10118259 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02837089 0,1010351 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02837089 0,10088803 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02837089 0,10074139 ! neuroprotection GO:0043526 8 5 0,000 0,02837089 0,10059518 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02837089 0,10044939 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02837089 0,10030402 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02837089 0,10015907 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02837089 0,10001454 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02837089 0,09987043 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02837089 0,09972673 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02837089 0,09958344 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02837089 0,09944057 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02837089 0,0992981 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02837089 0,09915605 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02837089 0,09901439 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02837089 0,09887315 ! spindle assembly GO:0051225 6 5 0,000 0,02837089 0,0987323 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02837089 0,09859186 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02837089 0,09845181 ! protein palmitoylation GO:0018345 12 5 0,000 0,02837089 0,09831216 ! drug metabolic process GO:0017144 7 5 0,000 0,02837089 0,09817291 ! stem cell division GO:0017145 11 5 0,000 0,02837089 0,09803405 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02837089 0,09789559 ! organ regeneration GO:0031100 7 5 0,000 0,02837089 0,09775751 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02837089 0,09761983 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02837089 0,09748253 ! glycolysis GO:0006096 71 46 1,000 0,02875575 0,09866613 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,02875575 0,09852775 ! leukocyte migration GO:0050900 75 46 1,000 0,02875575 0,09838976 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02875575 0,09825215 ! positive regulation of defense response GO:0031349 88 48 1,000 0,03110743 0,10613891 ! mitochondrial transport GO:0006839 94 48 1,000 0,03110743 0,10599087 ! response to calcium ion GO:0051592 94 49 1,000 0,03231089 0,10993804 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,03231089 0,10978513 ! JNK cascade GO:0007254 106 49 1,000 0,03231089 0,10963265 ! regulation of action potential GO:0001508 102 50 1,000 0,03353243 0,1136196 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,03353243 0,11346223 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,03353243 0,1133053 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03394821 0,11455175 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03394821 0,11439375 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03394821 0,11423618 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03394821 0,11407905 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03394821 0,11392234 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03394821 0,11376607 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03394821 0,11361023 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03394821 0,11345481 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03394821 0,11329982 ! response to oxygen radical GO:0000305 11 6 0,000 0,03394821 0,11314525 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03394821 0,1129911 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03394821 0,11283737 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03394821 0,11268406 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03394821 0,11253116 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03394821 0,11237868 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03394821 0,11222661 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03394821 0,11207495 ! forebrain regionalization GO:0021871 9 6 0,000 0,03394821 0,11192371 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03394821 0,11177287 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03394821 0,11162243 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03394821 0,1114724 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03394821 0,11132277 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03394821 0,11117355 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03394821 0,11102472 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03394821 0,11087629 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03394821 0,11072826 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03394821 0,11058062 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03394821 0,11043338 ! malate metabolic process GO:0006108 13 6 0,000 0,03394821 0,11028652 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03394821 0,11014006 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03394821 0,10999399 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03394821 0,1098483 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03394821 0,109703 ! protein refolding GO:0042026 15 6 0,000 0,03394821 0,10955808 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03394821 0,10941354 ! opsonization GO:0008228 8 6 0,000 0,03394821 0,10926939 ! mating behavior GO:0007617 7 6 0,000 0,03394821 0,10912561 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03394821 0,10898222 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03394821 0,10883919 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03394821 0,10869655 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03394821 0,10855428 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03394821 0,10841237 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03394821 0,10827084 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03394821 0,10812968 ! toxin metabolic process GO:0009404 11 6 0,000 0,03394821 0,10798889 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03394821 0,10784846 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03394821 0,1077084 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03394821 0,1075687 ! nuclear migration GO:0007097 13 6 0,000 0,03394821 0,10742936 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03394821 0,10729038 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03394821 0,10715177 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03394821 0,1070135 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03394821 0,1068756 ! thymic T cell selection GO:0045061 16 6 0,000 0,03394821 0,10673805 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03394821 0,10660086 ! protein lipoylation GO:0009249 10 6 0,000 0,03394821 0,10646401 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03394821 0,10632752 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03394821 0,10619138 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03394821 0,10605558 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03394821 0,10592014 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03394821 0,10578503 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03394821 0,10565028 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03394821 0,10551586 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03394821 0,10538179 ! hyperosmotic response GO:0006972 10 6 0,000 0,03394821 0,10524805 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03394821 0,10511466 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03394821 0,1049816 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03394821 0,10484888 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03394821 0,1047165 ! urea metabolic process GO:0019627 7 6 0,000 0,03394821 0,10458445 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03394821 0,10445273 ! neutrophil activation GO:0042119 7 6 0,000 0,03394821 0,10432134 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03394821 0,10419028 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03394821 0,10405956 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03394821 0,10392916 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03394821 0,10379908 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03394821 0,10366933 ! neuron apoptosis GO:0051402 15 6 0,000 0,03394821 0,10353991 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03394821 0,10341081 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03394821 0,10328203 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03394821 0,10315356 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03394821 0,10302542 ! carnitine transport GO:0015879 10 6 0,000 0,03394821 0,1028976 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03394821 0,10277009 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03394821 0,1026429 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03394821 0,10251603 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03394821 0,10238946 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03394821 0,10226321 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03394821 0,10213727 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03394821 0,10201164 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03394821 0,10188632 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03394821 0,10176131 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03394821 0,1016366 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,03394821 0,1015122 ! astrocyte development GO:0014002 16 6 0,000 0,03394821 0,1013881 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03394821 0,10126431 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03394821 0,10114081 ! interaction with symbiont GO:0051702 14 6 0,000 0,03394821 0,10101762 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03394821 0,10089473 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03394821 0,10077213 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03394821 0,10064984 ! response to copper ion GO:0046688 10 6 0,000 0,03394821 0,10052784 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03394821 0,10040613 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03394821 0,10028472 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03394821 0,10016361 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03394821 0,10004278 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03394821 0,09992225 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03394821 0,09980201 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03394821 0,09968205 ! hair follicle maturation GO:0048820 8 6 0,000 0,03394821 0,09956238 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03394821 0,099443 ! Schwann cell development GO:0014044 15 6 0,000 0,03394821 0,09932391 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03394821 0,0992051 ! response to pheromone GO:0019236 6 6 0,000 0,03394821 0,09908658 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03394821 0,09896834 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03394821 0,09885038 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03394821 0,0987327 ! subpallium development GO:0021544 15 6 0,000 0,03394821 0,0986153 ! neural tube patterning GO:0021532 8 6 0,000 0,03394821 0,09849818 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03394821 0,09838134 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03394821 0,09826477 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03394821 0,09814848 ! G2 phase GO:0051319 16 6 0,000 0,03394821 0,09803247 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03394821 0,09791673 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03394821 0,09780126 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03394821 0,09768606 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03394821 0,09757114 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03394821 0,09745648 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03394821 0,0973421 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03394821 0,09722798 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03394821 0,09711413 ! receptor internalization GO:0031623 11 6 0,000 0,03394821 0,09700055 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03394821 0,09688723 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03394821 0,09677417 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03394821 0,09666138 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03394821 0,09654885 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03394821 0,09643659 ! protein deubiquitination GO:0016579 16 6 0,000 0,03394821 0,09632458 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03394821 0,09621284 ! protein destabilization GO:0031648 9 6 0,000 0,03394821 0,09610135 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03394821 0,09599012 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03394821 0,09587915 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03394821 0,09576844 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03394821 0,09565798 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03394821 0,09554777 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03394821 0,09543782 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03394821 0,09532812 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03394821 0,09521868 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03394821 0,09510948 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03394821 0,09500053 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03394821 0,09489184 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03394821 0,09478339 ! neural plate development GO:0001840 9 6 0,000 0,03394821 0,09467519 ! catecholamine transport GO:0051937 9 6 0,000 0,03394821 0,09456724 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03394821 0,09445953 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03394821 0,09435207 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03394821 0,09424485 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03394821 0,09413787 ! maternal placenta development GO:0001893 12 6 0,000 0,03394821 0,09403114 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03394821 0,09392465 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03394821 0,0938184 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03394821 0,09371239 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03394821 0,09360662 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03394821 0,09350109 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03394821 0,0933958 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03394821 0,09329074 GO:0055081|anion homeostasis, ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,03477181 0,09544666 ! peptide metabolic process GO:0006518 80 51 1,000 0,03477181 0,09533954 ! response to temperature stimulus GO:0009266 84 51 1,000 0,03477181 0,09523265 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03477181 0,09512601 ! Notch signaling pathway GO:0007219 111 52 1,000 0,03602878 0,09845448 ! excretion GO:0007588 87 52 1,000 0,03602878 0,09834447 ! histone modification GO:0016570 104 52 1,000 0,03602878 0,09823471 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,03602878 0,0981252 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,03602878 0,09801593 ! amino acid activation GO:0043038 98 52 1,000 0,03602878 0,0979069 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! chromatin remodeling GO:0006338 122 53 1,000 0,0373031 0,10125719 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,0373031 0,1011448 ! protein amino acid lipidation GO:0006497 109 54 1,000 0,03859453 0,10453043 ! covalent chromatin modification GO:0016569 115 54 1,000 0,03859453 0,10441467 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,03859453 0,10429916 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03949367 0,10661108 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03949367 0,10649341 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03949367 0,10637599 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03949367 0,10625884 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03949367 0,10614194 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03949367 0,1060253 ! sleep GO:0030431 16 7 0,000 0,03949367 0,10590892 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03949367 0,10579279 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03949367 0,10567692 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03949367 0,1055613 ! prostate gland development GO:0030850 14 7 0,000 0,03949367 0,10544593 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03949367 0,10533081 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03949367 0,10521595 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03949367 0,10510134 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03949367 0,10498697 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03949367 0,10487285 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03949367 0,10475899 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03949367 0,10464536 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03949367 0,10453199 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03949367 0,10441886 ! glycolipid transport GO:0046836 11 7 0,000 0,03949367 0,10430597 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03949367 0,10419333 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03949367 0,10408093 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03949367 0,10396878 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03949367 0,10385686 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03949367 0,10374519 ! mRNA stabilization GO:0048255 18 7 0,000 0,03949367 0,10363375 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03949367 0,10352256 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03949367 0,1034116 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03949367 0,10330088 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03949367 0,1031904 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03949367 0,10308016 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03949367 0,10297014 ! lipoprotein transport GO:0042953 14 7 0,000 0,03949367 0,10286037 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03949367 0,10275083 ! rhythmic behavior GO:0007622 17 7 0,000 0,03949367 0,10264152 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03949367 0,10253244 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03949367 0,10242359 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03949367 0,10231498 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03949367 0,10220659 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03949367 0,10209844 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03949367 0,10199051 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03949367 0,10188281 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03949367 0,10177534 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03949367 0,1016681 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03949367 0,10156108 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03949367 0,10145429 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03949367 0,10134772 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03949367 0,10124137 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03949367 0,10113525 ! spinal cord patterning GO:0021511 14 7 0,000 0,03949367 0,10102935 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03949367 0,10092367 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03949367 0,10081821 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03949367 0,10071297 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03949367 0,10060795 ! adrenal gland development GO:0030325 17 7 0,000 0,03949367 0,10050315 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03949367 0,10039857 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03949367 0,10029421 ! ovulation GO:0030728 10 7 0,000 0,03949367 0,10019006 ! adenohypophysis development GO:0021984 11 7 0,000 0,03949367 0,10008613 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03949367 0,09998241 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03949367 0,09987891 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03949367 0,09977562 ! microtubule nucleation GO:0007020 21 7 0,000 0,03949367 0,09967255 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03949367 0,09956969 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03949367 0,09946704 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03949367 0,0993646 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03949367 0,09926237 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03949367 0,09916036 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03949367 0,09905855 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03949367 0,09895695 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03949367 0,09885556 ! galactose metabolic process GO:0006012 13 7 0,000 0,03949367 0,09875438 ! response to dietary excess GO:0002021 8 7 0,000 0,03949367 0,0986534 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03949367 0,09855263 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03949367 0,09845207 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03949367 0,09835171 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03949367 0,09825155 ! nucleoside transport GO:0015858 11 7 0,000 0,03949367 0,0981516 ! nucleoside salvage GO:0043174 11 7 0,000 0,03949367 0,09805186 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03949367 0,09795231 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03949367 0,09785297 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03949367 0,09775383 ! parturition GO:0007567 16 7 0,000 0,03949367 0,09765488 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03949367 0,09755614 ! rRNA modification GO:0000154 14 7 0,000 0,03949367 0,0974576 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03949367 0,09735926 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03949367 0,09726111 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03949367 0,09716317 ! monocyte differentiation GO:0030224 16 7 0,000 0,03949367 0,09706542 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03949367 0,09696786 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03949367 0,09687051 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03949367 0,09677335 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03949367 0,09667638 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03949367 0,09657961 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03949367 0,09648303 ! fibrinolysis GO:0042730 11 7 0,000 0,03949367 0,09638664 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03949367 0,09629044 ! eating behavior GO:0042755 8 7 0,000 0,03949367 0,09619444 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03949367 0,09609863 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03949367 0,09600301 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03949367 0,09590758 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03949367 0,09581234 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03949367 0,09571729 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03949367 0,09562242 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03949367 0,09552775 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03949367 0,09543326 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03949367 0,09533896 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03949367 0,09524484 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03949367 0,09515091 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03949367 0,09505717 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03949367 0,09496361 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03949367 0,09487023 ! histone ubiquitination GO:0016574 9 7 0,000 0,03949367 0,09477704 ! regulation of meiosis GO:0040020 12 7 0,000 0,03949367 0,09468403 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03949367 0,0945912 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03949367 0,09449856 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03949367 0,09440609 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03949367 0,09431381 ! transcription termination GO:0006353 14 7 0,000 0,03949367 0,0942217 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03949367 0,09412978 ! anaphase GO:0051322 18 7 0,000 0,03949367 0,09403804 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 19 7 0,000 0,03949367 0,09394647 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03949367 0,09385508 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03949367 0,09376387 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,03949367 0,09367284 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03949367 0,09358198 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03949367 0,0934913 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03949367 0,0934008 ! antibiotic transport GO:0042891 9 7 0,000 0,03949367 0,09331047 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03949367 0,09322031 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03949367 0,09313033 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03949367 0,09304053 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03949367 0,09295089 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03949367 0,09286143 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03949367 0,09277214 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03949367 0,09268302 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03949367 0,09259407 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03949367 0,0925053 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03949367 0,09241669 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03949367 0,09232825 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03949367 0,09223999 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03949367 0,09215189 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03949367 0,09206396 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03949367 0,09197619 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03949367 0,0918886 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03949367 0,09180117 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03949367 0,0917139 ! muscle adaptation GO:0043500 13 7 0,000 0,03949367 0,0916268 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03949367 0,09153987 ! retina homeostasis GO:0001895 12 7 0,000 0,03949367 0,0914531 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03949367 0,0913665 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03949367 0,09128006 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03949367 0,09119379 ! cell recognition GO:0008037 98 55 1,000 0,03990285 0,09205161 ! cell maturation GO:0048469 107 55 1,000 0,03990285 0,09196477 ! response to UV GO:0009411 120 55 1,000 0,03990285 0,09187809 ! glucose catabolic process GO:0006007 88 56 1,000 0,0412278 0,09483947 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,0412278 0,09475025 ! RNA elongation GO:0006354 90 56 1,000 0,0412278 0,0946612 ! heart morphogenesis GO:0003007 105 57 1,000 0,04256917 0,09764927 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,04256917 0,09755767 ! lipoprotein biosynthetic process GO:0042158 115 58 1,000 0,04392672 0,10057448 ! aging GO:0007568 112 58 1,000 0,04392672 0,10048031 ! gastrulation GO:0007369 122 58 1,000 0,04392672 0,10038631 ! maintenance of location GO:0051235 124 58 1,000 0,04392672 0,10029249 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04500745 0,10266405 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04500745 0,10256828 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,04500745 0,10247269 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04500745 0,10237728 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04500745 0,10228204 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04500745 0,10218699 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04500745 0,1020921 ! male meiosis GO:0007140 9 8 0,000 0,04500745 0,1019974 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04500745 0,10190287 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04500745 0,10180852 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04500745 0,10171434 ! meiotic prophase I GO:0007128 14 8 0,000 0,04500745 0,10162033 ! response to zinc ion GO:0010043 12 8 0,000 0,04500745 0,1015265 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04500745 0,10143284 ! oligopeptide transport GO:0006857 16 8 0,000 0,04500745 0,10133935 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04500745 0,10124604 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04500745 0,10115289 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04500745 0,10105992 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04500745 0,10096712 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04500745 0,10087449 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04500745 0,10078203 ! succinate metabolic process GO:0006105 17 8 0,000 0,04500745 0,10068974 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04500745 0,10059762 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04500745 0,10050566 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04500745 0,10041388 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04500745 0,10032226 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04500745 0,10023081 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04500745 0,10013952 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04500745 0,1000484 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04500745 0,09995745 ! reflex GO:0060004 17 8 0,000 0,04500745 0,09986666 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04500745 0,09977604 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04500745 0,09968558 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04500745 0,09959529 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04500745 0,09950516 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04500745 0,09941519 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04500745 0,09932538 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04500745 0,09923574 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04500745 0,09914625 ! histidine catabolic process GO:0006548 10 8 0,000 0,04500745 0,09905693 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04500745 0,09896777 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04500745 0,09887877 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04500745 0,09878993 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04500745 0,09870125 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04500745 0,09861273 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04500745 0,09852437 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04500745 0,09843617 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04500745 0,09834812 ! macrophage activation GO:0042116 13 8 0,000 0,04500745 0,09826023 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04500745 0,0981725 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04500745 0,09808492 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04500745 0,0979975 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04500745 0,09791024 ! purine salvage GO:0043101 12 8 0,000 0,04500745 0,09782313 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04500745 0,09773617 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04500745 0,09764938 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04500745 0,09756273 ! osteoblast development GO:0002076 17 8 0,000 0,04500745 0,09747624 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04500745 0,0973899 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04500745 0,09730371 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04500745 0,09721768 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04500745 0,0971318 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04500745 0,09704607 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04500745 0,09696049 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04500745 0,09687506 ! intermediate filament organization GO:0045109 12 8 0,000 0,04500745 0,09678979 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04500745 0,09670466 ! cellular extravasation GO:0045123 13 8 0,000 0,04500745 0,09661968 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04500745 0,09653485 ! response to antibiotic GO:0046677 11 8 0,000 0,04500745 0,09645017 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04500745 0,09636564 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04500745 0,09628126 ! DNA topological change GO:0006265 12 8 0,000 0,04500745 0,09619702 ! response to tropane GO:0014073 15 8 0,000 0,04500745 0,09611293 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,04500745 0,09602899 ! melanosome transport GO:0032402 13 8 0,000 0,04500745 0,0959452 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04500745 0,09586155 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04500745 0,09577805 ! mast cell activation GO:0045576 14 8 0,000 0,04500745 0,09569469 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04500745 0,09561148 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04500745 0,09552841 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04500745 0,09544548 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04500745 0,0953627 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04500745 0,09528007 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04500745 0,09519757 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04500745 0,09511522 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04500745 0,09503301 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04500745 0,09495095 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04500745 0,09486902 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04500745 0,09478724 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04500745 0,0947056 ! response to tumor cell GO:0002347 16 8 0,000 0,04500745 0,09462409 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04500745 0,09454273 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04500745 0,09446151 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04500745 0,09438043 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04500745 0,09429948 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04500745 0,09421868 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04500745 0,09413801 ! hormone catabolic process GO:0042447 17 8 0,000 0,04500745 0,09405748 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04500745 0,09397709 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04500745 0,09389684 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04500745 0,09381672 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04500745 0,09373674 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04500745 0,0936569 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04500745 0,09357719 ! adult feeding behavior GO:0008343 10 8 0,000 0,04500745 0,09349762 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04500745 0,09341818 ! ATP catabolic process GO:0006200 11 8 0,000 0,04500745 0,09333888 ! blastocyst growth GO:0001832 19 8 0,000 0,04500745 0,09325971 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04500745 0,09318067 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04500745 0,09310178 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04500745 0,09302301 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04500745 0,09294438 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04500745 0,09286588 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04500745 0,09278751 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04500745 0,09270927 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04500745 0,09263117 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04500745 0,0925532 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04500745 0,09247535 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04500745 0,09239764 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04500745 0,09232006 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04500745 0,09224261 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04500745 0,09216529 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04500745 0,0920881 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04500745 0,09201104 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04500745 0,09193411 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04500745 0,09185731 ! nuclear export GO:0051168 110 59 1,000 0,04530022 0,09237766 ! establishment of organelle localization GO:0051656 122 59 1,000 0,04530022 0,09230061 ! lipid modification GO:0030258 112 60 1,000 0,04668945 0,09505193 ! adult behavior GO:0030534 104 60 1,000 0,04668945 0,09497279 ! kidney development GO:0001822 133 60 1,000 0,04668945 0,09489377 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,04809418 0,09766756 ! regulation of heart contraction GO:0008016 123 61 1,000 0,04809418 0,09758644 ! viral reproductive process GO:0022415 132 62 1,000 0,04951419 0,10038438 ! tRNA processing GO:0008033 102 62 1,000 0,04951419 0,10030114 ! axon extension GO:0048675 16 9 0,000 0,05048973 0,10219256 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05048973 0,10210796 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05048973 0,10202351 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05048973 0,10193919 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05048973 0,10185501 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05048973 0,10177097 ! reproductive behavior GO:0019098 22 9 0,000 0,05048973 0,10168707 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05048973 0,10160331 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05048973 0,10151969 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05048973 0,1014362 ! UTP metabolic process GO:0046051 10 9 0,000 0,05048973 0,10135285 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05048973 0,10126964 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,05048973 0,10118656 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05048973 0,10110362 ! artery development GO:0060840 25 9 0,000 0,05048973 0,10102082 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05048973 0,10093815 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05048973 0,10085562 ! equilibrioception GO:0050957 20 9 0,000 0,05048973 0,10077322 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05048973 0,10069095 ! chemosensory behavior GO:0007635 21 9 0,000 0,05048973 0,10060882 ! microtubule bundle formation GO:0001578 22 9 0,000 0,05048973 0,10052683 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05048973 0,10044497 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05048973 0,10036324 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05048973 0,10028164 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05048973 0,10020018 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05048973 0,10011885 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05048973 0,10003765 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05048973 0,09995658 ! protein targeting to ER GO:0045047 25 9 0,000 0,05048973 0,09987564 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05048973 0,09979484 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05048973 0,09971416 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05048973 0,09963362 ! glycine catabolic process GO:0006546 15 9 0,000 0,05048973 0,0995532 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05048973 0,09947292 ! endosome organization GO:0007032 20 9 0,000 0,05048973 0,09939276 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05048973 0,09931274 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05048973 0,09923284 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05048973 0,09915307 ! mannose metabolic process GO:0006013 13 9 0,000 0,05048973 0,09907343 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05048973 0,09899392 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05048973 0,09891453 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05048973 0,09883527 ! receptor clustering GO:0043113 20 9 0,000 0,05048973 0,09875614 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05048973 0,09867713 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05048973 0,09859826 ! retinol metabolic process GO:0042572 20 9 0,000 0,05048973 0,0985195 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05048973 0,09844088 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05048973 0,09836238 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05048973 0,098284 ! macrophage differentiation GO:0030225 15 9 0,000 0,05048973 0,09820575 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05048973 0,09812762 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05048973 0,09804962 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05048973 0,09797174 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05048973 0,09789398 ! response to amine stimulus GO:0014075 13 9 0,000 0,05048973 0,09781635 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05048973 0,09773884 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05048973 0,09766146 ! erythrocyte development GO:0048821 17 9 0,000 0,05048973 0,09758419 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05048973 0,09750705 ! renal water homeostasis GO:0003091 15 9 0,000 0,05048973 0,09743003 ! postreplication repair GO:0006301 25 9 0,000 0,05048973 0,09735313 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05048973 0,09727636 ! icosanoid secretion GO:0032309 15 9 0,000 0,05048973 0,0971997 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05048973 0,09712316 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05048973 0,09704675 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05048973 0,09697045 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05048973 0,09689428 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05048973 0,09681823 ! sterol catabolic process GO:0016127 14 9 0,000 0,05048973 0,09674229 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05048973 0,09666647 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05048973 0,09659077 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05048973 0,09651519 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05048973 0,09643973 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05048973 0,09636439 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05048973 0,09628916 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05048973 0,09621406 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05048973 0,09613906 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05048973 0,09606419 ! purine base metabolic process GO:0006144 25 9 0,000 0,05048973 0,09598943 ! pigment granule transport GO:0051904 17 9 0,000 0,05048973 0,09591479 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05048973 0,09584026 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05048973 0,09576585 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05048973 0,09569156 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05048973 0,09561738 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05048973 0,09554331 ! mitochondrion localization GO:0051646 18 9 0,000 0,05048973 0,09546936 ! mesoderm development GO:0007498 128 63 1,000 0,05094927 0,09626378 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,05094927 0,09618939 ! glycerophospholipid biosynthetic process GO:0046474 116 64 1,000 0,05239919 0,09885037 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,05386374 0,10153482 GO:0048609|reproductive process in a multicellular organism, ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,05386374 0,10145653 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,05386374 0,10137837 ! gonad development GO:0008406 115 66 1,000 0,05534271 0,10408178 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,05534271 0,10400172 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0559407 0,10504468 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,0559407 0,104964 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0559407 0,10488345 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0559407 0,10480301 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0559407 0,1047227 ! associative learning GO:0008306 21 10 0,000 0,0559407 0,10464252 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,0559407 0,10456246 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0559407 0,10448252 ! phosphate transport GO:0006817 24 10 0,000 0,0559407 0,1044027 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0559407 0,104323 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0559407 0,10424342 ! CTP metabolic process GO:0046036 11 10 0,000 0,0559407 0,10416397 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0559407 0,10408464 ! GTP metabolic process GO:0046039 11 10 0,000 0,0559407 0,10400543 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0559407 0,10392633 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0559407 0,10384736 ! social behavior GO:0035176 29 10 0,000 0,0559407 0,10376851 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0559407 0,10368978 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0559407 0,10361117 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0559407 0,10353267 ! androgen metabolic process GO:0008209 17 10 0,000 0,0559407 0,1034543 ! phospholipid efflux GO:0033700 19 10 0,000 0,0559407 0,10337604 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0559407 0,10329791 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0559407 0,10321989 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0559407 0,10314198 ! lung alveolus development GO:0048286 26 10 0,000 0,0559407 0,1030642 ! pathogenesis GO:0009405 17 10 0,000 0,0559407 0,10298653 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0559407 0,10290898 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0559407 0,10283155 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0559407 0,10275423 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0559407 0,10267703 ! endoderm development GO:0007492 18 10 0,000 0,0559407 0,10259995 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0559407 0,10252298 ! arginine catabolic process GO:0006527 17 10 0,000 0,0559407 0,10244612 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0559407 0,10236939 ! proline metabolic process GO:0006560 13 10 0,000 0,0559407 0,10229276 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0559407 0,10221625 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0559407 0,10213986 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0559407 0,10206358 ! V(D)J recombination GO:0033151 34 10 0,000 0,0559407 0,10198741 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0559407 0,10191136 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0559407 0,10183542 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0559407 0,10175959 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0559407 0,10168388 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0559407 0,10160828 ! multicellular organism growth GO:0035264 19 10 0,000 0,0559407 0,10153279 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0559407 0,10145741 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0559407 0,10138214 ! ruffle organization GO:0031529 17 10 0,000 0,0559407 0,10130699 ! epithelial cell development GO:0002064 21 10 0,000 0,0559407 0,10123195 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0559407 0,10115702 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0559407 0,1010822 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0559407 0,10100749 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0559407 0,10093289 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0559407 0,1008584 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0559407 0,10078402 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0559407 0,10070975 ! motor axon guidance GO:0008045 22 10 0,000 0,0559407 0,10063559 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0559407 0,10056154 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0559407 0,1004876 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0559407 0,10041376 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0559407 0,10034004 ! segment specification GO:0007379 15 10 0,000 0,0559407 0,10026642 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0559407 0,10019291 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0559407 0,10011951 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0559407 0,10004622 ! DNA ligation GO:0006266 18 10 0,000 0,0559407 0,09997303 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0559407 0,09989995 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0559407 0,09982698 ! melanosome localization GO:0032400 16 10 0,000 0,0559407 0,09975411 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0559407 0,09968135 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0559407 0,0996087 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0559407 0,09953615 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0559407 0,0994637 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0559407 0,09939137 ! induction of an organ GO:0001759 17 10 0,000 0,0559407 0,09931914 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0559407 0,09924701 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0559407 0,09917499 ! protein sumoylation GO:0016925 17 10 0,000 0,0559407 0,09910307 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0559407 0,09903125 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0559407 0,09895954 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0559407 0,09888794 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0559407 0,09881644 ! salivary gland development GO:0007431 28 10 0,000 0,0559407 0,09874504 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0559407 0,09867374 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0559407 0,09860255 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0559407 0,09853146 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0559407 0,09846047 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0559407 0,09838958 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0559407 0,0983188 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0559407 0,09824812 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0559407 0,09817754 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0559407 0,09810706 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0559407 0,09803668 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0559407 0,0979664 ! detection of calcium ion GO:0005513 24 10 0,000 0,0559407 0,09789622 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0559407 0,09782615 ! blastocyst formation GO:0001825 18 10 0,000 0,0559407 0,09775617 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0559407 0,0976863 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0559407 0,09761652 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0559407 0,09754685 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0559407 0,09747727 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0559407 0,09740779 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0559407 0,09733841 ! activation of MAPK activity GO:0000187 124 67 1,000 0,05683588 0,09882565 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,05683588 0,09875537 ! secondary metabolic process GO:0019748 125 67 1,000 0,05683588 0,09868518 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,05683588 0,09861509 ! hexose catabolic process GO:0019320 113 68 1,000 0,05834304 0,1011583 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,05834304 0,10108655 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,05834304 0,10101491 ! viral reproduction GO:0016032 142 68 1,000 0,05834304 0,10094337 ! adaptive immune response GO:0002250 126 68 1,000 0,05834304 0,10087193 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,05986398 0,10342837 ! urogenital system development GO:0001655 149 69 1,000 0,05986398 0,10335527 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,05986398 0,10328228 ! developmental maturation GO:0021700 128 69 1,000 0,05986398 0,10320939 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,06136053 0,10571493 ! respiratory burst GO:0045730 17 11 0,000 0,06136053 0,10564043 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,06136053 0,10556603 ! neuron fate specification GO:0048665 18 11 0,000 0,06136053 0,10549174 ! telencephalon cell migration GO:0022029 23 11 0,000 0,06136053 0,10541756 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,06136053 0,10534347 ! thyroid gland development GO:0030878 26 11 0,000 0,06136053 0,1052695 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,06136053 0,10519562 ! synapsis GO:0007129 14 11 0,000 0,06136053 0,10512185 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06136053 0,10504819 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,06136053 0,10497463 ! response to pain GO:0048265 27 11 0,000 0,06136053 0,10490117 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06136053 0,10482781 ! blood vessel remodeling GO:0001974 30 11 0,000 0,06136053 0,10475455 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,06136053 0,1046814 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,06136053 0,10460835 ! bone resorption GO:0045453 16 11 0,000 0,06136053 0,1045354 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06136053 0,10446255 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,06136053 0,10438981 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06136053 0,10431716 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06136053 0,10424462 ! melanocyte differentiation GO:0030318 20 11 0,000 0,06136053 0,10417218 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,06136053 0,10409984 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,06136053 0,1040276 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,06136053 0,10395545 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,06136053 0,10388341 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,06136053 0,10381147 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,06136053 0,10373963 ! UV protection GO:0009650 20 11 0,000 0,06136053 0,10366789 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,06136053 0,10359624 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06136053 0,1035247 ! macroautophagy GO:0016236 19 11 0,000 0,06136053 0,10345325 ! temperature homeostasis GO:0001659 18 11 0,000 0,06136053 0,10338191 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,06136053 0,10331066 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,06136053 0,10323951 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,06136053 0,10316845 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,06136053 0,1030975 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06136053 0,10302664 ! regulation of organ growth GO:0046620 14 11 0,000 0,06136053 0,10295588 ! pigment granule localization GO:0051875 20 11 0,000 0,06136053 0,10288522 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,06136053 0,10281465 ! vasoconstriction GO:0042310 20 11 0,000 0,06136053 0,10274418 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,06136053 0,10267381 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06136053 0,10260354 ! embryonic axis specification GO:0000578 19 11 0,000 0,06136053 0,10253335 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06136053 0,10246327 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06136053 0,10239328 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,06136053 0,10232339 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,06136053 0,10225359 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06136053 0,10218389 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06136053 0,10211428 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06136053 0,10204477 ! prophase GO:0051324 17 11 0,000 0,06136053 0,10197535 ! neuroblast proliferation GO:0007405 25 11 0,000 0,06136053 0,10190603 ! nucleosome positioning GO:0016584 15 11 0,000 0,06136053 0,1018368 ! regulation of isotype switching GO:0045191 24 11 0,000 0,06136053 0,10176766 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06136053 0,10169862 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06136053 0,10162967 ! apical protein localization GO:0045176 18 11 0,000 0,06136053 0,10156082 ! acid secretion GO:0046717 20 11 0,000 0,06136053 0,10149205 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06136053 0,10142339 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06136053 0,10135481 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,06136053 0,10128633 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,06136053 0,10121794 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,06136053 0,10114964 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06136053 0,10108143 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,06136053 0,10101332 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06136053 0,1009453 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,06136053 0,10087737 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,06136053 0,10080953 ! embryonic gut development GO:0048566 19 11 0,000 0,06136053 0,10074178 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06136053 0,10067412 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,06136053 0,10060655 ! activation of innate immune response GO:0002218 16 11 0,000 0,06136053 0,10053908 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06136053 0,10047169 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06136053 0,1004044 ! lysogeny GO:0030069 22 11 0,000 0,06136053 0,10033719 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06136053 0,10027008 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,06136053 0,10020305 ! nucleus localization GO:0051647 22 11 0,000 0,06136053 0,10013612 ! germ cell development GO:0007281 133 70 1,000 0,06139851 0,10013121 ! activation of immune response GO:0002253 120 70 1,000 0,06139851 0,10006441 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,06294641 0,10251872 ! carbohydrate transport GO:0008643 114 72 1,000 0,06450748 0,10499119 ! B cell activation GO:0042113 179 72 1,000 0,06450748 0,10492129 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,06450748 0,10485148 ! glycerolipid biosynthetic process GO:0045017 130 73 1,000 0,06608152 0,10733854 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06674939 0,10835133 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06674939 0,10827939 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,06674939 0,10820754 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,06674939 0,10813578 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06674939 0,10806412 ! protein complex disassembly GO:0043241 28 12 0,000 0,06674939 0,10799255 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06674939 0,10792108 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06674939 0,10784971 ! hippocampus development GO:0021766 29 12 0,000 0,06674939 0,10777842 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06674939 0,10770724 ! T cell proliferation GO:0042098 32 12 0,000 0,06674939 0,10763614 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06674939 0,10756514 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06674939 0,10749424 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06674939 0,10742342 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06674939 0,1073527 ! drug transport GO:0015893 16 12 0,000 0,06674939 0,10728208 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06674939 0,10721154 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06674939 0,1071411 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06674939 0,10707075 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06674939 0,1070005 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06674939 0,10693033 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06674939 0,10686026 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06674939 0,10679028 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06674939 0,10672039 ! lipid digestion GO:0044241 21 12 0,000 0,06674939 0,10665059 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06674939 0,10658089 ! entry into host cell GO:0030260 34 12 0,000 0,06674939 0,10651127 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06674939 0,10644175 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06674939 0,10637231 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06674939 0,10630297 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06674939 0,10623372 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06674939 0,10616455 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06674939 0,10609548 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06674939 0,1060265 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06674939 0,10595761 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06674939 0,1058888 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06674939 0,10582009 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06674939 0,10575146 ! cranial nerve development GO:0021545 23 12 0,000 0,06674939 0,10568293 ! fucose catabolic process GO:0019317 25 12 0,000 0,06674939 0,10561448 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06674939 0,10554612 ! histone acetylation GO:0016573 27 12 0,000 0,06674939 0,10547785 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06674939 0,10540967 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06674939 0,10534157 ! zymogen activation GO:0031638 18 12 0,000 0,06674939 0,10527357 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06674939 0,10520565 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06674939 0,10513782 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06674939 0,10507007 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06674939 0,10500242 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06674939 0,10493485 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06674939 0,10486737 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,06674939 0,10479997 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06674939 0,10473266 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06674939 0,10466544 ! defense response to fungus GO:0050832 15 12 0,000 0,06674939 0,1045983 ! developmental induction GO:0031128 22 12 0,000 0,06674939 0,10453125 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06674939 0,10446429 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06674939 0,10439741 ! response to cold GO:0009409 17 12 0,000 0,06674939 0,10433062 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06674939 0,10426391 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06674939 0,10419729 ! localization within membrane GO:0051668 26 12 0,000 0,06674939 0,10413075 ! acute inflammatory response GO:0002526 118 74 1,000 0,06766834 0,10549698 ! organelle localization GO:0051640 155 74 1,000 0,06766834 0,10542969 ! reproductive structure development GO:0048608 131 75 1,000 0,06926774 0,10785282 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,06926774 0,10778413 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,06926774 0,10771552 ! axon guidance GO:0007411 162 75 1,000 0,06926774 0,107647 ! rhythmic process GO:0048511 142 75 1,000 0,06926774 0,10757856 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,07087951 0,11001185 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07210746 0,11184669 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07210746 0,11177572 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07210746 0,11170484 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07210746 0,11163405 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07210746 0,11156335 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07210746 0,11149274 ! peroxisomal transport GO:0043574 28 13 0,000 0,07210746 0,11142222 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07210746 0,11135179 ! cartilage condensation GO:0001502 22 13 0,000 0,07210746 0,11128145 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,07210746 0,1112112 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07210746 0,11114103 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07210746 0,11107095 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07210746 0,11100097 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,07210746 0,11093107 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07210746 0,11086125 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07210746 0,11079153 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07210746 0,11072189 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07210746 0,11065235 ! methionine metabolic process GO:0006555 31 13 0,000 0,07210746 0,11058288 ! plasma membrane organization GO:0007009 27 13 0,000 0,07210746 0,11051351 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07210746 0,11044422 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07210746 0,11037502 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07210746 0,11030591 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07210746 0,11023688 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,07210746 0,11016794 ! cytokine metabolic process GO:0042107 24 13 0,000 0,07210746 0,11009908 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,07210746 0,11003031 ! exocrine system development GO:0035272 34 13 0,000 0,07210746 0,10996163 ! asymmetric protein localization GO:0008105 24 13 0,000 0,07210746 0,10989303 ! monoamine transport GO:0015844 21 13 0,000 0,07210746 0,10982452 ! L-glutamate transport GO:0015813 30 13 0,000 0,07210746 0,1097561 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07210746 0,10968775 ! protein homotetramerization GO:0051289 24 13 0,000 0,07210746 0,1096195 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07210746 0,10955133 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07210746 0,10948324 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07210746 0,10941524 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07210746 0,10934732 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07210746 0,10927949 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07210746 0,10921174 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,07210746 0,10914407 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07210746 0,10907649 ! chromatin silencing GO:0006342 29 13 0,000 0,07210746 0,10900899 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07210746 0,10894158 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,07210746 0,10887425 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07210746 0,108807 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07210746 0,10873984 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,07210746 0,10867275 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07210746 0,10860575 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,07210746 0,10853884 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07210746 0,108472 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07210746 0,10840525 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07210746 0,10833858 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07210746 0,10827199 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07210746 0,10820549 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,07210746 0,10813906 ! insulin secretion GO:0030073 24 13 0,000 0,07210746 0,10807272 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,07210746 0,10800646 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,07210746 0,10794028 ! acrosome reaction GO:0007340 19 13 0,000 0,07210746 0,10787418 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07210746 0,10780816 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07210746 0,10774222 ! amine catabolic process GO:0009310 136 77 1,000 0,07250348 0,10826772 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,07250348 0,10820159 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,07250348 0,10813553 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,07413944 0,11050802 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07743493 0,11534971 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07743493 0,11527942 ! water transport GO:0006833 21 14 0,000 0,07743493 0,11520921 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07743493 0,11513909 ! non-recombinational repair GO:0000726 29 14 0,000 0,07743493 0,11506905 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07743493 0,1149991 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07743493 0,11492924 ! palate development GO:0060021 32 14 0,000 0,07743493 0,11485946 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,07743493 0,11478976 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07743493 0,11472015 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07743493 0,11465062 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07743493 0,11458118 ! arginine metabolic process GO:0006525 21 14 0,000 0,07743493 0,11451182 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07743493 0,11444254 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07743493 0,11437335 ! regulation of heart rate GO:0002027 25 14 0,000 0,07743493 0,11430424 ! organic alcohol transport GO:0015850 29 14 0,000 0,07743493 0,11423522 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07743493 0,11416628 ! embryo implantation GO:0007566 30 14 0,000 0,07743493 0,11409742 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07743493 0,11402865 ! bone mineralization GO:0030282 18 14 0,000 0,07743493 0,11395995 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07743493 0,11389135 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07743493 0,11382282 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07743493 0,11375437 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07743493 0,11368601 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07743493 0,11361773 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07743493 0,11354953 ! ribosome assembly GO:0042255 18 14 0,000 0,07743493 0,11348142 ! cerebellum development GO:0021549 23 14 0,000 0,07743493 0,11341338 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07743493 0,11334543 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07743493 0,11327756 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07743493 0,11320977 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07743493 0,11314206 ! NADP metabolic process GO:0006739 24 14 0,000 0,07743493 0,11307443 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07743493 0,11300688 ! oxygen transport GO:0015671 22 14 0,000 0,07743493 0,11293942 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07743493 0,11287203 ! regulation of axon extension GO:0030516 43 14 0,000 0,07743493 0,11280473 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07743493 0,1127375 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,0774466 0,11268734 ! muscle cell differentiation GO:0042692 178 81 1,000 0,07911742 0,11504991 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,07911742 0,11498147 ! lactation GO:0007595 30 15 0,000 0,08273195 0,12016299 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,08273195 0,1200916 ! reproductive cellular process GO:0048610 22 15 0,000 0,08273195 0,12002028 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08273195 0,11994905 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,08273195 0,11987791 ! superoxide anion generation GO:0042554 22 15 0,000 0,08273195 0,11980685 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08273195 0,11973587 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08273195 0,11966498 ! copper ion transport GO:0006825 22 15 0,000 0,08273195 0,11959417 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,08273195 0,11952345 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08273195 0,11945281 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08273195 0,11938225 ! sulfate transport GO:0008272 27 15 0,000 0,08273195 0,11931178 ! response to cAMP GO:0051591 25 15 0,000 0,08273195 0,11924139 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08273195 0,11917108 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08273195 0,11910086 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,08273195 0,11903072 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08273195 0,11896066 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08273195 0,11889068 ! vesicle coating GO:0006901 38 15 0,000 0,08273195 0,11882079 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,08273195 0,11875097 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,08273195 0,11868124 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08273195 0,11861159 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08273195 0,11854203 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,08273195 0,11847254 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08273195 0,11840314 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08273195 0,11833381 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08273195 0,11826457 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,08273195 0,11819541 ! histone deacetylation GO:0016575 24 15 0,000 0,08273195 0,11812633 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08273195 0,11805733 ! water homeostasis GO:0030104 28 15 0,000 0,08273195 0,11798842 ! cofactor transport GO:0051181 30 15 0,000 0,08273195 0,11791958 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08273195 0,11785082 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08273195 0,11778214 ! intestinal absorption GO:0050892 31 15 0,000 0,08273195 0,11771354 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08273195 0,11764503 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08273195 0,11757659 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08273195 0,11750823 ! cell killing GO:0001906 32 15 0,000 0,08273195 0,11743995 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,08273195 0,11737175 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,08273195 0,11730363 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08273195 0,11723559 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08273195 0,11716763 ! actin filament polymerization GO:0030041 27 15 0,000 0,08273195 0,11709974 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08273195 0,11703194 ! T cell activation GO:0042110 189 84 1,000 0,08419665 0,11903497 ! response to nutrient GO:0007584 135 84 1,000 0,08419665 0,11896612 ! negative regulation of transport GO:0051051 164 85 1,000 0,08591138 0,12131879 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08799871 0,1241946 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08799871 0,12412289 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08799871 0,12405127 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08799871 0,12397973 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08799871 0,12390827 ! bone remodeling GO:0046849 28 16 0,000 0,08799871 0,12383689 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08799871 0,1237656 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08799871 0,12369439 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08799871 0,12362326 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08799871 0,12355221 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08799871 0,12348125 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08799871 0,12341036 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08799871 0,12333956 ! startle response GO:0001964 28 16 0,000 0,08799871 0,12326883 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08799871 0,12319819 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08799871 0,12312763 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08799871 0,12305715 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08799871 0,12298675 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08799871 0,12291644 ! response to osmotic stress GO:0006970 27 16 0,000 0,08799871 0,1228462 ! lysosomal transport GO:0007041 31 16 0,000 0,08799871 0,12277604 ! L-amino acid transport GO:0015807 33 16 0,000 0,08799871 0,12270596 ! stem cell development GO:0048864 46 16 0,000 0,08799871 0,12263597 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08799871 0,12256605 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08799871 0,12249621 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08799871 0,12242645 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08799871 0,12235677 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08799871 0,12228717 ! axon cargo transport GO:0008088 46 16 0,000 0,08799871 0,12221765 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08799871 0,12214821 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08799871 0,12207885 ! DNA replication initiation GO:0006270 28 16 0,000 0,08799871 0,12200956 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08799871 0,12194036 ! tissue regeneration GO:0042246 27 16 0,000 0,08799871 0,12187123 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08799871 0,12180218 ! biomineral formation GO:0031214 22 16 0,000 0,08799871 0,12173321 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08799871 0,12166432 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08799871 0,1215955 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08799871 0,12152677 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08799871 0,12145811 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08799871 0,12138952 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08799871 0,12132102 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08799871 0,12125259 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,08799871 0,12118424 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08799871 0,12111597 ! peptide hormone processing GO:0016486 27 16 0,000 0,08799871 0,12104777 ! alcohol catabolic process GO:0046164 142 87 1,000 0,08937225 0,12286799 ! nucleosome assembly GO:0006334 126 87 1,000 0,08937225 0,12279888 ! chromatin assembly GO:0031497 128 88 1,000 0,09111804 0,12512725 ! tube morphogenesis GO:0035239 194 89 1,000 0,09287384 0,12746674 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,09323538 0,12789108 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,09323538 0,12781932 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,09323538 0,12774763 ! signal complex assembly GO:0007172 47 17 0,000 0,09323538 0,12767602 ! filopodium assembly GO:0046847 42 17 0,000 0,09323538 0,12760449 ! endothelial cell migration GO:0043542 31 17 0,000 0,09323538 0,12753305 ! gene silencing by RNA GO:0031047 38 17 0,000 0,09323538 0,12746168 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,09323538 0,12739039 ! glial cell development GO:0021782 28 17 0,000 0,09323538 0,12731919 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09323538 0,12724806 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,09323538 0,12717701 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09323538 0,12710604 ! myoblast differentiation GO:0045445 50 17 0,000 0,09323538 0,12703515 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,09323538 0,12696434 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09323538 0,12689361 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09323538 0,12682295 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,09323538 0,12675238 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,09323538 0,12668188 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,09323538 0,12661146 ! membrane budding GO:0006900 42 17 0,000 0,09323538 0,12654112 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09323538 0,12647086 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,09323538 0,12640068 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09323538 0,12633057 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09323538 0,12626054 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,09323538 0,12619059 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09323538 0,12612072 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,09323538 0,12605093 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09323538 0,12598121 ! steroid catabolic process GO:0006706 34 17 0,000 0,09323538 0,12591157 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,09323538 0,125842 ! gas transport GO:0015669 26 17 0,000 0,09323538 0,12577251 ! organic cation transport GO:0015695 32 17 0,000 0,09323538 0,1257031 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,09323538 0,12563377 ! ossification GO:0001503 205 91 1,000 0,09641477 0,12984635 ! bone development GO:0060348 206 92 1,000 0,09819956 0,13217715 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,09819956 0,13210437 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,09819956 0,13203166 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09844212 0,13228498 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09844212 0,13221226 ! limbic system development GO:0021761 40 18 0,000 0,09844212 0,13213961 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09844212 0,13206705 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09844212 0,13199456 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09844212 0,13192216 ! heart looping GO:0001947 34 18 0,000 0,09844212 0,13184983 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09844212 0,13177759 ! centrosome cycle GO:0007098 26 18 0,000 0,09844212 0,13170542 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09844212 0,13163333 ! glycine metabolic process GO:0006544 30 18 0,000 0,09844212 0,13156132 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09844212 0,13148939 ! response to retinoic acid GO:0032526 31 18 0,000 0,09844212 0,13141754 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09844212 0,13134577 ! DNA integration GO:0015074 32 18 0,000 0,09844212 0,13127407 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,09844212 0,13120245 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09844212 0,13113091 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09844212 0,13105945 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09844212 0,13098807 ! neural crest cell migration GO:0001755 41 18 0,000 0,09844212 0,13091676 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09844212 0,13084554 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09844212 0,13077439 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09844212 0,13070331 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09844212 0,13063232 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09844212 0,1305614 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09844212 0,13049056 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09844212 0,13041979 ! detection of bacterium GO:0016045 22 18 0,000 0,09844212 0,1303491 ! nerve development GO:0021675 34 18 0,000 0,09844212 0,13027849 ! microspike assembly GO:0030035 46 18 0,000 0,09844212 0,13020796 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09844212 0,1301375 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,09844212 0,13006712 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,10179699 0,13442705 ! female pregnancy GO:0007565 166 94 1,000 0,10179699 0,13435442 ! nucleosome organization GO:0034728 143 95 1,000 0,10360928 0,13667251 ! phospholipid biosynthetic process GO:0008654 188 95 1,000 0,10360928 0,13659875 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,10360928 0,13652507 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,10361911 0,13646441 ! positive regulation of translation GO:0045727 31 19 0,000 0,10361911 0,13639089 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,10361911 0,13631744 ! neuron maturation GO:0042551 46 19 0,000 0,10361911 0,13624407 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,10361911 0,13617078 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,10361911 0,13609757 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,10361911 0,13602444 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,10361911 0,13595139 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,10361911 0,13587842 ! inositol metabolic process GO:0006020 33 19 0,000 0,10361911 0,13580552 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10361911 0,1357327 ! memory GO:0007613 34 19 0,000 0,10361911 0,13565996 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,10361911 0,1355873 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,10361911 0,13551472 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,10361911 0,13544221 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,10361911 0,13536978 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,10361911 0,13529743 ! cerebral cortex development GO:0021987 40 19 0,000 0,10361911 0,13522515 ! response to vitamin A GO:0033189 32 19 0,000 0,10361911 0,13515296 ! heme metabolic process GO:0042168 40 19 0,000 0,10361911 0,13508084 ! neuromuscular junction development GO:0007528 43 19 0,000 0,10361911 0,13500879 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,10361911 0,13493683 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,10361911 0,13486494 ! response to fungus GO:0009620 26 19 0,000 0,10361911 0,13479312 ! peptide cross-linking GO:0018149 39 19 0,000 0,10361911 0,13472139 ! protein export from nucleus GO:0006611 40 19 0,000 0,10361911 0,13464973 ! heart process GO:0003015 32 19 0,000 0,10361911 0,13457814 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,10361911 0,13450664 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,10361911 0,1344352 ! visual learning GO:0008542 38 19 0,000 0,10361911 0,13436385 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,10361911 0,13429257 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,10361911 0,13422136 ! vitamin transport GO:0051180 31 19 0,000 0,10361911 0,13415023 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,10361911 0,13407918 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,10361911 0,1340082 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,10361911 0,1339373 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,10361911 0,13386647 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,10361911 0,13379571 ! cilium assembly GO:0042384 38 19 0,000 0,10361911 0,13372503 ! peptide hormone secretion GO:0030072 32 19 0,000 0,10361911 0,13365443 ! response to protein stimulus GO:0051789 158 96 1,000 0,10543043 0,13591901 ! protein secretion GO:0009306 45 20 0,000 0,10876652 0,14014589 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10876652 0,14007201 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,10876652 0,13999821 ! positive regulation of ossification GO:0045778 50 20 0,000 0,10876652 0,13992449 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10876652 0,13985085 ! skin development GO:0043588 42 20 0,000 0,10876652 0,13977728 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,10876652 0,13970379 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,10876652 0,13963038 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,10876652 0,13955704 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10876652 0,13948378 ! response to vitamin GO:0033273 36 20 0,000 0,10876652 0,1394106 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,10876652 0,1393375 ! bile acid metabolic process GO:0008206 34 20 0,000 0,10876652 0,13926447 ! retinoid metabolic process GO:0001523 34 20 0,000 0,10876652 0,13919152 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10876652 0,13911864 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,10876652 0,13904584 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,10876652 0,13897312 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,10876652 0,13890047 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10876652 0,1388279 ! peptide secretion GO:0002790 38 20 0,000 0,10876652 0,13875541 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10876652 0,13868299 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,10876652 0,13861065 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10876652 0,13853838 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,10876652 0,13846618 ! cell-cell junction organization GO:0045216 43 20 0,000 0,10876652 0,13839407 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10876652 0,13832202 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,10876652 0,13825006 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,10876652 0,13817816 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10876652 0,13810635 ! regulation of glucose import GO:0046324 30 20 0,000 0,10876652 0,1380346 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,10876652 0,13796293 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,10876652 0,13789134 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10876652 0,13781982 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,10876652 0,13774837 ! leukocyte differentiation GO:0002521 232 98 1,000 0,1090986 0,13809735 ! positive regulation of immune response GO:0050778 175 100 1,000 0,11280025 0,14270896 ! regulation of cell killing GO:0031341 46 21 0,000 0,11388451 0,14400614 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,11388451 0,14393164 ! hormone secretion GO:0046879 39 21 0,000 0,11388451 0,14385722 ! cAMP metabolic process GO:0046058 41 21 0,000 0,11388451 0,14378288 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,11388451 0,14370861 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,11388451 0,14363442 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,11388451 0,1435603 ! smooth muscle contraction GO:0006939 48 21 0,000 0,11388451 0,14348627 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,11388451 0,1434123 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,11388451 0,14333842 ! plasma membrane fusion GO:0045026 33 21 0,000 0,11388451 0,14326461 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,11388451 0,14319087 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,11388451 0,14311722 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,11388451 0,14304363 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,11388451 0,14297013 ! collagen fibril organization GO:0030199 62 21 0,000 0,11388451 0,1428967 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,11388451 0,14282334 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,11388451 0,14275006 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,11388451 0,14267686 ! collagen catabolic process GO:0030574 29 21 0,000 0,11388451 0,14260373 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,11388451 0,14253067 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,11388451 0,14245769 ! sperm-egg recognition GO:0035036 23 21 0,000 0,11388451 0,14238478 ! actin filament-based movement GO:0030048 47 21 0,000 0,11388451 0,14231195 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,11388451 0,1422392 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11897326 0,148519 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11897326 0,14844314 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11897326 0,14836737 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11897326 0,14829167 ! microtubule-based transport GO:0010970 59 22 0,000 0,11897326 0,14821605 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,11897326 0,14814051 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11897326 0,14806504 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11897326 0,14798965 ! vacuolar transport GO:0007034 41 22 0,000 0,11897326 0,14791434 ! fucose metabolic process GO:0006004 44 22 0,000 0,11897326 0,1478391 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11897326 0,14776394 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11897326 0,14768886 ! stem cell differentiation GO:0048863 57 22 0,000 0,11897326 0,14761385 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11897326 0,14753892 ! cytolysis GO:0019835 27 22 0,000 0,11897326 0,14746407 ! vasodilation GO:0042311 40 22 0,000 0,11897326 0,14738929 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11897326 0,14731459 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,11897326 0,14723996 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11897326 0,14716541 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11897326 0,14709093 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11897326 0,14701653 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11897326 0,1469422 ! sarcomere organization GO:0045214 32 22 0,000 0,11897326 0,14686795 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,11897326 0,14679378 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11897326 0,14671968 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11897326 0,14664565 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11897326 0,1465717 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11897326 0,14649782 ! protein stabilization GO:0050821 41 22 0,000 0,11897326 0,14642402 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,12403293 0,15257424 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,12403293 0,15249745 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,12403293 0,15242074 ! gluconeogenesis GO:0006094 38 23 0,000 0,12403293 0,15234411 ! glycerol metabolic process GO:0006071 40 23 0,000 0,12403293 0,15226756 ! viral genome replication GO:0019079 44 23 0,000 0,12403293 0,15219108 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,12403293 0,15211468 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,12403293 0,15203835 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,12403293 0,15196211 ! axis specification GO:0009798 43 23 0,000 0,12403293 0,15188594 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,12403293 0,15180984 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,12403293 0,15173382 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,12403293 0,15165788 ! peroxisome organization GO:0007031 43 23 0,000 0,12403293 0,15158201 ! lysosome organization GO:0007040 47 23 0,000 0,12403293 0,15150622 ! vesicle targeting GO:0006903 49 23 0,000 0,12403293 0,15143051 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,12403293 0,15135487 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,12403293 0,1512793 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,12403293 0,15120381 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,12403293 0,1511284 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,12403293 0,15105306 ! fatty acid transport GO:0015908 47 23 0,000 0,12403293 0,1509778 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,12403293 0,15090261 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,12403293 0,1508275 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,12403293 0,15075246 ! hormone transport GO:0009914 41 23 0,000 0,12403293 0,15067749 ! cell-cell recognition GO:0009988 28 23 0,000 0,12403293 0,1506026 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,12403293 0,15052779 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,12403293 0,15045305 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,12403293 0,15037838 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,12906368 0,15640008 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12906368 0,15632254 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,12906368 0,15624508 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12906368 0,15616769 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12906368 0,15609038 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12906368 0,15601314 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,12906368 0,15593599 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,12906368 0,1558589 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,12906368 0,1557819 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,12906368 0,15570497 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12906368 0,15562812 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,12906368 0,15555134 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,12906368 0,15547464 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12906368 0,15539801 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12906368 0,15532146 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12906368 0,15524498 ! pallium development GO:0021543 56 24 0,000 0,12906368 0,15516858 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,12906368 0,15509226 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12906368 0,15501601 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,12906368 0,15493983 ! platelet activation GO:0030168 41 24 0,000 0,12906368 0,15486373 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,12906368 0,15478771 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12906368 0,15471176 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12906368 0,15463588 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12906368 0,15456008 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,12906368 0,15448435 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,12906368 0,1544087 ! regulation of amine transport GO:0051952 41 24 0,000 0,12906368 0,15433312 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,13406568 0,16023603 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,13406568 0,16015768 ! leukocyte adhesion GO:0007159 55 25 0,000 0,13406568 0,1600794 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,13406568 0,1600012 ! phototransduction GO:0007602 37 25 0,000 0,13406568 0,15992307 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,13406568 0,15984502 ! vacuole organization GO:0007033 49 25 0,000 0,13406568 0,15976705 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,13406568 0,15968915 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,13406568 0,15961133 ! receptor metabolic process GO:0043112 53 25 0,000 0,13406568 0,15953358 ! chromosome condensation GO:0030261 48 25 0,000 0,13406568 0,15945591 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,13406568 0,15937832 ! regulation of behavior GO:0050795 48 25 0,000 0,13406568 0,1593008 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,13406568 0,15922336 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,13406568 0,15914599 ! immunoglobulin production GO:0002377 62 25 0,000 0,13406568 0,1590687 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,13406568 0,15899148 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,13406568 0,15891434 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13903909 0,16472963 ! myelination GO:0042552 50 26 0,000 0,13903909 0,16464978 ! initiation of viral infection GO:0019059 60 26 0,000 0,13903909 0,16457001 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13903909 0,16449031 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13903909 0,16441069 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13903909 0,16433115 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,13903909 0,16425169 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,13903909 0,1641723 ! digestive system process GO:0022600 49 26 0,000 0,13903909 0,16409299 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13903909 0,16401376 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,13903909 0,1639346 GO:0045936|negative regulation of phosphate metabolic process, ! neural crest cell development GO:0014032 59 26 0,000 0,13903909 0,16385552 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13903909 0,16377651 ! negative regulation of cell development GO:0010721 83 26 0,000 0,13903909 0,16369759 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13903909 0,16361873 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,13903909 0,16353996 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,13903909 0,16346126 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,13903909 0,16338263 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13903909 0,16330408 ! blastocyst development GO:0001824 50 26 0,000 0,13903909 0,16322561 ! telomere organization GO:0032200 46 26 0,000 0,13903909 0,16314721 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13903909 0,16306889 ! neural tube closure GO:0001843 58 26 0,000 0,13903909 0,16299064 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,13903909 0,16291247 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13903909 0,16283437 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13903909 0,16275635 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,14398407 0,16846413 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,14398407 0,16838348 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,14398407 0,16830292 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,14398407 0,16822243 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,14398407 0,16814201 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,14398407 0,16806168 ! iron ion transport GO:0006826 65 27 0,000 0,14398407 0,16798142 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,14398407 0,16790124 ! superoxide metabolic process GO:0006801 41 27 0,000 0,14398407 0,16782113 ! tube lumen formation GO:0035148 59 27 0,000 0,14398407 0,1677411 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,14398407 0,16766115 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,14398407 0,16758127 ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,14398407 0,16750147 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,1489008 0,17313881 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,1489008 0,17305645 ! protein amino acid acylation GO:0043543 59 28 0,000 0,1489008 0,17297415 ! circadian rhythm GO:0007623 56 28 0,000 0,1489008 0,17289194 ! dendrite development GO:0016358 67 28 0,000 0,1489008 0,17280981 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,1489008 0,17272775 ! fat cell differentiation GO:0045444 57 28 0,000 0,1489008 0,17264578 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,1489008 0,17256387 ! sperm motility GO:0030317 37 28 0,000 0,1489008 0,17248205 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,1489008 0,17240031 ! base-excision repair GO:0006284 41 28 0,000 0,1489008 0,17231864 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,1489008 0,17223705 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,1489008 0,17215554 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,1489008 0,1720741 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,1489008 0,17199274 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,1489008 0,17191146 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,1489008 0,17183025 ! glutathione metabolic process GO:0006749 42 28 0,000 0,1489008 0,17174913 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,1489008 0,17166807 ! lipid oxidation GO:0034440 48 28 0,000 0,1489008 0,1715871 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,1489008 0,1715062 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,1489008 0,17142538 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,15378942 0,17697011 ! translational initiation GO:0006413 66 29 0,000 0,15378942 0,17688679 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,15378942 0,17680355 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,15378942 0,17672039 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,15378942 0,1766373 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,15378942 0,1765543 ! primary neural tube formation GO:0014020 61 29 0,000 0,15378942 0,17647137 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,15378942 0,17638852 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,15378942 0,17630575 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,15378942 0,17622305 ! somitogenesis GO:0001756 52 29 0,000 0,15378942 0,17614043 ! synaptogenesis GO:0007416 46 29 0,000 0,15378942 0,17605789 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,15378942 0,17597543 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,15378942 0,17589305 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,1586501 0,18136742 ! phenol metabolic process GO:0018958 56 30 0,000 0,1586501 0,18128259 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,1586501 0,18119784 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,1586501 0,18111317 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,1586501 0,18102858 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,1586501 0,18094406 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,1586501 0,18085963 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,1586501 0,18077527 ! acute-phase response GO:0006953 50 30 0,000 0,1586501 0,18069099 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,1586501 0,1806068 ! myofibril assembly GO:0030239 50 30 0,000 0,1586501 0,18052267 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,1586501 0,18043863 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,1586501 0,18035467 ! phospholipid transport GO:0015914 65 30 0,000 0,1586501 0,18027078 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,1586501 0,18018697 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,1586501 0,18010324 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,1586501 0,18001959 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,1586501 0,17993602 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 0,000 0,1586501 0,17985252 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,16348299 0,18524533 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,16348299 0,18515945 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,16348299 0,18507365 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,16348299 0,18498793 ! regulation of innate immune response GO:0045088 57 31 0,000 0,16348299 0,18490229 ! peptide transport GO:0015833 60 31 0,000 0,16348299 0,18481672 ! detection of light stimulus GO:0009583 44 31 0,000 0,16348299 0,18473124 ! natural killer cell activation GO:0030101 50 31 0,000 0,16348299 0,18464583 ! ensheathment of neurons GO:0007272 64 31 0,000 0,16348299 0,18456051 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,16348299 0,18447526 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,16348299 0,18439009 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,16348299 0,184305 ! eye morphogenesis GO:0048592 65 31 0,000 0,16348299 0,18421999 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,16348299 0,18413506 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,16828826 0,18946 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,16828826 0,18937274 ! collagen metabolic process GO:0032963 49 32 0,000 0,16828826 0,18928555 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,16828826 0,18919844 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,16828826 0,18911141 ! muscle cell development GO:0055001 52 32 0,000 0,16828826 0,18902446 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,16828826 0,1889376 ! peripheral nervous system development GO:0007422 68 32 0,000 0,16828826 0,18885081 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,16828826 0,1887641 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,16828826 0,18867747 ! gene silencing GO:0016458 71 32 0,000 0,16828826 0,18859092 ! regulation of pH GO:0006885 56 33 0,000 0,17306606 0,1938562 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,17306606 0,19376736 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,17306606 0,19367859 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,17306606 0,19358991 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,17306606 0,19350131 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,17306606 0,1934128 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,17306606 0,19332436 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,17306606 0,193236 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,17306606 0,19314773 ! glial cell differentiation GO:0010001 67 34 0,000 0,17781654 0,19835882 ! spliceosome assembly GO:0000245 75 34 0,000 0,17781654 0,19826828 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,17781654 0,19817783 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,17781654 0,19808747 ! cell fate specification GO:0001708 56 34 0,000 0,17781654 0,19799718 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,17781654 0,19790698 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,18253987 0,20307145 ! negative regulation of secretion GO:0051048 68 35 0,000 0,18253987 0,20297902 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,18253987 0,20288667 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,18253987 0,20279441 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,18253987 0,20270223 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,18253987 0,20261013 ! ceramide metabolic process GO:0006672 72 35 0,000 0,18253987 0,20251812 ! telencephalon development GO:0021537 81 35 0,000 0,18253987 0,20242619 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,18253987 0,20233435 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,18253987 0,20224259 ! placenta development GO:0001890 53 35 0,000 0,18253987 0,20215091 ! vesicle localization GO:0051648 70 35 0,000 0,18253987 0,20205931 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,1872362 0,20716396 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,1872362 0,20707018 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,1872362 0,20697648 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,1872362 0,20688287 ! protein targeting to membrane GO:0006612 75 36 0,000 0,1872362 0,20678934 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,1872362 0,2066959 ! aerobic respiration GO:0009060 56 36 0,000 0,1872362 0,20660254 ! embryonic organ development GO:0048568 67 36 0,000 0,1872362 0,20650927 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,1872362 0,20641608 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,1872362 0,20632297 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,19190568 0,21137311 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,19190568 0,21127786 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,19190568 0,21118269 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,19190568 0,2110876 ! actomyosin structure organization GO:0031032 68 37 0,000 0,19190568 0,2109926 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,19190568 0,21089769 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,19190568 0,21080286 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,19190568 0,21070812 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,19654846 0,21570884 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,19654846 0,21561198 ! organic anion transport GO:0015711 82 38 0,000 0,19654846 0,21551521 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,19654846 0,21541852 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,19654846 0,21532192 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,19654846 0,21522541 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,19654846 0,21512898 ! spermatid development GO:0007286 69 38 0,000 0,19654846 0,21503264 ! neural tube formation GO:0001841 79 38 0,000 0,19654846 0,21493638 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,20116469 0,21988606 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,20116469 0,21978772 ! negative regulation of binding GO:0051100 71 39 0,000 0,20116469 0,21968947 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,20116469 0,21959131 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,20116469 0,21949323 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,20116469 0,21939524 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,20116469 0,21929734 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,20575454 0,22420086 ! learning GO:0007612 82 40 0,000 0,20575454 0,22410091 ! mismatch repair GO:0006298 58 40 0,000 0,20575454 0,22400104 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,20575454 0,22390126 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,20575454 0,22380157 ! RNA export from nucleus GO:0006405 61 41 0,000 0,21031814 0,22866365 ! mRNA catabolic process GO:0006402 79 41 0,000 0,21031814 0,22856193 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,21031814 0,2284603 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,21031814 0,22835876 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,21031814 0,22825731 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,21031814 0,22815596 ! gliogenesis GO:0042063 91 41 0,000 0,21031814 0,22805469 ! feeding behavior GO:0007631 69 41 0,000 0,21031814 0,22795351 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,21031814 0,22785242 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,21031814 0,22775142 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,21031814 0,22765051 ! spermatid differentiation GO:0048515 73 41 0,000 0,21031814 0,2275497 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,21031814 0,22744897 ! RNA modification GO:0009451 64 41 0,000 0,21031814 0,22734832 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,21485565 0,23215053 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,21485565 0,2320479 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,21485565 0,23194536 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,21485565 0,23184291 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,21485565 0,23174055 ! regulation of protein secretion GO:0050708 77 42 0,000 0,21485565 0,23163828 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,21485565 0,2315361 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,21936721 0,23629369 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,21936721 0,23618955 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,21936721 0,2360855 ! regulation of tube size GO:0035150 76 43 0,000 0,21936721 0,23598154 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,21936721 0,23587768 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,21936721 0,2357739 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,21936721 0,23567022 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,21936721 0,23556663 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,21936721 0,23546313 ! segmentation GO:0035282 78 43 0,000 0,21936721 0,23535972 ! ion transmembrane transport GO:0034220 79 43 0,000 0,21936721 0,2352564 ! neuron migration GO:0001764 85 43 0,000 0,21936721 0,23515317 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,22385297 0,23985649 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,22385297 0,23975134 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,22385297 0,23964628 ! striated muscle contraction GO:0006941 85 44 0,000 0,22385297 0,23954131 ! phagocytosis GO:0006909 105 44 0,000 0,22385297 0,23943643 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,22385297 0,23933164 ! double-strand break repair GO:0006302 85 44 0,000 0,22385297 0,23922695 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,22831308 0,24388669 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,22831308 0,2437801 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,22831308 0,2436736 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,22831308 0,24356719 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,22831308 0,24346087 ! polyol metabolic process GO:0019751 77 45 0,000 0,22831308 0,24335465 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,23274769 0,24797323 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,23274769 0,24786513 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,23274769 0,24775713 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,23274769 0,24764922 ! cell growth GO:0016049 90 46 0,000 0,23274769 0,2475414 ! neural tube development GO:0021915 91 47 0,000 0,23715694 0,25212115 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,23715694 0,25201148 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,24154097 0,25655852 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,24154097 0,25644702 ! endosome transport GO:0016197 127 48 0,000 0,24154097 0,25633562 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,24154097 0,25622431 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,24154097 0,2561131 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,24154097 0,25600199 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,24154097 0,25589098 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,24589993 0,26039598 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,24589993 0,26028316 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,24589993 0,26017043 ! regulation of ion transport GO:0043269 86 50 0,000 0,25023396 0,26464137 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,25023396 0,26452686 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,25023396 0,26441244 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,25023396 0,26429813 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,25023396 0,26418391 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,2545432 0,2686173 ! viral infectious cycle GO:0019058 104 51 0,000 0,2545432 0,26850131 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,2545432 0,26838543 ! positive regulation of binding GO:0051099 88 52 0,000 0,2588278 0,2727853 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,2588278 0,27266766 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,2588278 0,27255014 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,2588278 0,27243271 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,2588278 0,27231538 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,2588278 0,27219816 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,2588278 0,27208103 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,26308789 0,27644031 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,26308789 0,27632146 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,26308789 0,27620271 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,26308789 0,27608407 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,26308789 0,27596553 ! synapse organization GO:0050808 102 53 0,000 0,26308789 0,27584709 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,26732361 0,28016799 ! regulation of translational initiation GO:0006446 87 54 0,000 0,26732361 0,28004785 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,26732361 0,27992781 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,26732361 0,27980788 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,26732361 0,27968805 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,26732361 0,27956832 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,26732361 0,27944869 ! regulation of cell shape GO:0008360 142 54 0,000 0,26732361 0,27932917 ! RNA catabolic process GO:0006401 103 55 0,000 0,27153511 0,2836085 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,27153511 0,2834873 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,27153511 0,2833662 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,27153511 0,28324521 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,27572252 0,28749044 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,27572252 0,28736779 ! chloride transport GO:0006821 102 57 0,000 0,27988597 0,29158269 ! muscle fiber development GO:0048747 131 57 0,000 0,27988597 0,29145841 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,27988597 0,29133422 ! regulation of actin filament length GO:0030832 118 58 0,000 0,2840256 0,29551727 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,2840256 0,29539146 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,2840256 0,29526577 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,2840256 0,29514017 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,29223397 0,30354064 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,29223397 0,30341164 ! positive regulation of secretion GO:0051047 110 61 0,000 0,29630296 0,30750558 ! regulation of cellular component size GO:0032535 125 61 0,000 0,29630296 0,30737501 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,29630296 0,30724454 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,29630296 0,30711419 ! camera-type eye development GO:0043010 126 61 0,000 0,29630296 0,30698394 ! proton transport GO:0015992 117 61 0,000 0,29630296 0,30685381 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,30034868 0,31091179 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,30437125 0,31494238 ! hydrogen transport GO:0006818 121 64 0,000 0,30837081 0,31894576 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,30837081 0,31881079 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,31234748 0,32278549 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,31234748 0,32264901 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,3202327 0,33065447 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,3202327 0,33051478 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,3241415 0,3344078 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,3241415 0,33426664 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,3241415 0,3341256 ! regulation of lipase activity GO:0060191 137 68 0,000 0,3241415 0,33398468 ! cell projection assembly GO:0030031 138 68 0,000 0,3241415 0,33384388 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,32802793 0,33770427 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,32802793 0,33756202 ! single fertilization GO:0007338 83 69 0,000 0,32802793 0,33741989 ! cell redox homeostasis GO:0045454 114 70 0,000 0,33189213 0,34125104 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,33573421 0,34505624 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,33573421 0,34491113 ! appendage morphogenesis GO:0035107 150 72 0,000 0,3395543 0,34868901 GO:0035108|limb morphogenesis, ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,3395543 0,34854251 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,3395543 0,34839612 ! appendage development GO:0048736 151 73 0,000 0,34335254 0,35214536 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 156 73 0,000 0,34335254 0,35199759 ! amino acid transport GO:0006865 148 74 0,000 0,34712903 0,35571989 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,34712903 0,35557074 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,35088391 0,3592663 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,35088391 0,3591158 ! eye development GO:0001654 155 75 0,000 0,35088391 0,35896541 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,35461731 0,36263293 ! learning or memory GO:0007611 161 76 0,000 0,35461731 0,3624812 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,35461731 0,3623296 ! regulation of blood pressure GO:0008217 134 76 0,000 0,35461731 0,36217813 ! neurotransmitter transport GO:0006836 142 77 0,000 0,35832933 0,36581636 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,35832933 0,36566356 ! antigen processing and presentation GO:0019882 117 78 0,000 0,36202011 0,36927563 ! fertilization GO:0009566 99 78 0,000 0,36202011 0,3691215 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,36202011 0,36896751 ! blood coagulation GO:0007596 151 79 0,000 0,36568976 0,37255216 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,36568976 0,37239687 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,36568976 0,3722417 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,36568976 0,37208667 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,36933841 0,37564269 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,37296617 0,37917451 ! protein import into nucleus GO:0006606 174 82 0,000 0,37657317 0,3826823 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,38015952 0,38616619 ! exocytosis GO:0006887 153 83 0,000 0,38015952 0,38600569 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,38015952 0,38584532 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,38015952 0,38568509 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,38015952 0,38552499 ! nuclear import GO:0051170 177 83 0,000 0,38015952 0,38536502 ! inorganic anion transport GO:0015698 156 83 0,000 0,38015952 0,38520518 ! digestion GO:0007586 130 84 0,000 0,38372533 0,38865713 ! hemostasis GO:0007599 165 85 0,000 0,38727074 0,39208554 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,38727074 0,39192312 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,38727074 0,39176083 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,39079584 0,39516318 ! regulation of lyase activity GO:0051339 169 86 0,000 0,39079584 0,39499969 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,39079584 0,39483633 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,39430077 0,39821281 ! cellular respiration GO:0045333 143 88 0,000 0,39778563 0,40156624 ! amine biosynthetic process GO:0009309 146 88 0,000 0,39778563 0,40140037 ! sensory perception of smell GO:0007608 117 88 0,000 0,39778563 0,40123464 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,40125053 0,40456255 ! regulation of DNA binding GO:0051101 167 89 0,000 0,40125053 0,40439565 ! cellular defense response GO:0006968 123 89 0,000 0,40125053 0,40422889 ! protein localization in nucleus GO:0034504 192 89 0,000 0,40125053 0,40406227 ! regulation of neurological system process GO:0031644 175 89 0,000 0,40125053 0,40389578 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,4046956 0,40719578 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,4046956 0,40702814 ! response to unfolded protein GO:0006986 139 90 0,000 0,4046956 0,40686064 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,40812095 0,41013553 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,40812095 0,40996689 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,4149129 0,41661826 ! amine transport GO:0015837 181 93 0,000 0,4149129 0,41644709 ! vitamin metabolic process GO:0006766 153 93 0,000 0,4149129 0,41627607 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,41827974 0,41948169 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,4216273 0,42266536 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,4216273 0,422492 ! regulation of T cell activation GO:0050863 175 96 0,000 0,42495569 0,42565262 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,42826501 0,42879157 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,43155539 0,43190898 ! mRNA transport GO:0051028 185 100 0,000 0,43807972 0,43825911 ! hormone metabolic process GO:0042445 171 100 0,000 0,43807972 0,43807972