pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1242-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of lipid kinase activity GO:0043550 12 7 3,000 5,315E-09 1,223E-05 ! nuclear migration GO:0007097 10 5 2,000 4,437E-07 5,103E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 4,437E-07 3,402E-04 GO:0031272|regulation of pseudopodium assembly, ! macrophage differentiation GO:0030225 10 6 2,000 8,852E-07 5,09E-04 ! establishment of nucleus localization GO:0040023 13 7 2,000 1,545E-06 7,107E-04 ! regulation of lipid metabolic process GO:0019216 84 56 4,000 1,714E-06 6,572E-04 ! nucleus localization GO:0051647 15 9 2,000 3,689E-06 1,212E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 5,257E-06 1,511E-03 ! response to hypoxia GO:0001666 132 72 4,000 6,008E-06 1,535E-03 ! response to oxygen levels GO:0070482 137 74 4,000 6,879E-06 1,582E-03 ! filopodium assembly GO:0046847 19 11 2,000 7,209E-06 1,507E-03 ! microspike assembly GO:0030035 23 12 2,000 9,588E-06 1,838E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 1,701E-05 3,009E-03 ! response to estrogen stimulus GO:0043627 74 47 3,000 2,432E-05 3,995E-03 ! cell projection assembly GO:0030031 76 53 3,000 3,928E-05 6,023E-03 ! collagen catabolic process GO:0030574 25 20 2,000 4,867E-05 6,996E-03 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 5,664E-05 7,662E-03 ! lung development GO:0030324 94 59 3,000 6,007E-05 7,676E-03 ! myeloid cell differentiation GO:0030099 85 59 3,000 6,007E-05 7,272E-03 ! regulation of heart contraction GO:0008016 91 60 3,000 6,419E-05 7,381E-03 ! respiratory tube development GO:0030323 99 62 3,000 7,303E-05 7,999E-03 ! respiratory system development GO:0060541 100 64 3,000 8,274E-05 8,65E-03 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 8,553E-05 8,553E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 2,000 8,553E-05 8,196E-03 ! multicellular organismal catabolic process GO:0044243 32 26 2,000 1,093E-04 0,01005567 ! microvillus organization GO:0032528 7 5 1,000 1,269E-04 0,01122782 GO:0030033|microvillus assembly, ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,269E-04 0,01081197 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 1,269E-04 0,01042583 GO:0045686|negative regulation of glial cell differentiation, ! glial cell migration GO:0008347 10 5 1,000 1,269E-04 0,01006632 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 1,37E-04 0,01050432 ! response to steroid hormone stimulus GO:0048545 114 73 3,000 1,383E-04 0,01026397 ! collagen metabolic process GO:0032963 40 30 2,000 1,689E-04 0,01214199 ! response to mechanical stimulus GO:0009612 43 31 2,000 1,866E-04 0,01300211 ! positive regulation of protein ubiquitination GO:0031398 8 6 1,000 1,899E-04 0,01284903 ! positive regulation of DNA repair GO:0045739 7 6 1,000 1,899E-04 0,01248191 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,899E-04 0,01213519 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 1,899E-04 0,01180722 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 1,899E-04 0,0114965 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 1,899E-04 0,01120172 ! negative regulation of focal adhesion formation GO:0051895 16 6 1,000 1,899E-04 0,01092168 ! ossification GO:0001503 134 82 3,000 2,17E-04 0,01217252 GO:0060348|bone development, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 2,000 2,253E-04 0,01233651 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 2,253E-04 0,01204961 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 2,464E-04 0,01288222 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 2,606E-04 0,01332105 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,653E-04 0,01326505 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 1,000 2,653E-04 0,01298282 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 2,653E-04 0,01271234 ! neuroblast proliferation GO:0007405 13 7 1,000 2,653E-04 0,0124529 ! interphase GO:0051325 159 88 3,000 2,847E-04 0,01309454 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 3,529E-04 0,01591567 ! regulation of gliogenesis GO:0014013 20 8 1,000 3,529E-04 0,0156096 GO:0045685|regulation of glial cell differentiation, ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 3,529E-04 0,01531508 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 3,529E-04 0,01503147 ! induction of an organ GO:0001759 11 8 1,000 3,529E-04 0,01475817 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 1,000 3,529E-04 0,01449463 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 3,529E-04 0,01424034 ! multicellular organismal metabolic process GO:0044236 50 39 2,000 3,716E-04 0,01473495 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 3,969E-04 0,01547234 ! postreplication repair GO:0006301 11 9 1,000 4,527E-04 0,01735315 ! localization within membrane GO:0051668 15 9 1,000 4,527E-04 0,01706867 ! regulation of cell projection organization GO:0031344 83 44 2,000 5,316E-04 0,01972128 ! hippocampus development GO:0021766 19 10 1,000 5,645E-04 0,02061054 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 5,645E-04 0,0202885 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 1,000 5,645E-04 0,01997637 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 5,645E-04 0,01967369 ! zymogen activation GO:0031638 14 10 1,000 5,645E-04 0,01938006 ! developmental induction GO:0031128 13 10 1,000 5,645E-04 0,01909506 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 6,884E-04 0,02294676 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 6,884E-04 0,02261895 GO:0000725|recombinational repair, ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 6,884E-04 0,02230037 ! histone acetylation GO:0016573 23 12 1,000 8,242E-04 0,02632752 ! peptidyl-lysine modification GO:0018205 18 12 1,000 8,242E-04 0,02596687 ! establishment of organelle localization GO:0051656 85 52 2,000 8,691E-04 0,02701242 ! regulation of protein complex assembly GO:0043254 81 54 2,000 9,704E-04 0,02976039 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 9,718E-04 0,02940834 ! bone mineralization GO:0030282 15 13 1,000 9,718E-04 0,02902641 ! regulation of DNA repair GO:0006282 15 13 1,000 9,718E-04 0,02865428 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 9,718E-04 0,02829157 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 1,131E-03 0,03251862 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,131E-03 0,03211716 ! limbic system development GO:0021761 25 14 1,000 1,131E-03 0,03172549 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 1,195E-03 0,03311251 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 1,302E-03 0,03565186 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,302E-03 0,03523243 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 1,302E-03 0,03482275 ! lipid phosphorylation GO:0046834 23 15 1,000 1,302E-03 0,03442249 ! centrosome cycle GO:0007098 16 15 1,000 1,302E-03 0,03403133 ! biomineral formation GO:0031214 18 15 1,000 1,302E-03 0,03364895 ! organelle localization GO:0051640 96 62 2,000 1,45E-03 0,03704797 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,485E-03 0,03752354 ! G1 phase GO:0051318 27 16 1,000 1,485E-03 0,03711568 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 1,518E-03 0,03754934 ! cell cycle checkpoint GO:0000075 108 64 2,000 1,589E-03 0,03887736 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 1,679E-03 0,04064164 ! somitogenesis GO:0001756 24 18 1,000 1,884E-03 0,04514071 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 1,884E-03 0,04467534 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 2,101E-03 0,04930725 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 2,101E-03 0,04880919 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 2,101E-03 0,0483211 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 2,101E-03 0,04784268 ! tube morphogenesis GO:0035239 118 73 2,000 2,318E-03 0,05226799 ! iron ion transport GO:0006826 37 20 1,000 2,329E-03 0,05200557 ! hindlimb morphogenesis GO:0035137 32 20 1,000 2,329E-03 0,05150552 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 2,329E-03 0,05101499 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 2,329E-03 0,05053371 ! pallium development GO:0021543 38 20 1,000 2,329E-03 0,05006144 ! protein amino acid acylation GO:0043543 37 21 1,000 2,568E-03 0,05469178 ! ovarian follicle development GO:0001541 30 21 1,000 2,568E-03 0,05419002 ! microtubule organizing center organization GO:0031023 28 22 1,000 2,818E-03 0,05893035 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 2,818E-03 0,05839945 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 2,818E-03 0,05787803 ! neural tube closure GO:0001843 33 22 1,000 2,818E-03 0,05736583 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! cellular iron ion homeostasis GO:0006879 37 23 1,000 3,08E-03 0,06213395 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 3,08E-03 0,06159365 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 3,352E-03 0,06645967 ! primary neural tube formation GO:0014020 35 24 1,000 3,352E-03 0,06589163 ! negative regulation of cell development GO:0010721 56 24 1,000 3,352E-03 0,06533323 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 3,352E-03 0,06478421 ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 3,635E-03 0,06966924 ! iron ion homeostasis GO:0055072 39 25 1,000 3,635E-03 0,06909347 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 3,929E-03 0,074066 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 3,929E-03 0,07346384 ! leukocyte differentiation GO:0002521 143 90 2,000 4,192E-03 0,0777641 ! erythrocyte differentiation GO:0030218 38 28 1,000 4,548E-03 0,08368864 ! neural tube formation GO:0001841 41 28 1,000 4,548E-03 0,08302445 ! ovulation cycle process GO:0022602 41 29 1,000 4,874E-03 0,08826776 ! telencephalon development GO:0021537 52 29 1,000 4,874E-03 0,08757817 ! angiogenesis GO:0001525 149 95 2,000 4,877E-03 0,08695581 ! ovulation cycle GO:0042698 43 30 1,000 5,21E-03 0,09217667 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 5,21E-03 0,09147303 ! regulation of microtubule-based process GO:0032886 58 30 1,000 5,21E-03 0,09078005 ! segmentation GO:0035282 41 31 1,000 5,556E-03 0,09608863 ! cell fate specification GO:0001708 37 31 1,000 5,556E-03 0,09537155 ! leukocyte chemotaxis GO:0030595 43 31 1,000 5,556E-03 0,09466509 GO:0060326|cell chemotaxis, ! calcium-mediated signaling GO:0019722 50 32 1,000 5,913E-03 0,10000214 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 6,28E-03 0,10543285 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 6,28E-03 0,10466885 ! female gonad development GO:0008585 49 33 1,000 6,28E-03 0,10391583 ! erythrocyte homeostasis GO:0034101 45 34 1,000 6,657E-03 0,10936888 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 6,657E-03 0,10859322 ! Notch signaling pathway GO:0007219 56 35 1,000 7,044E-03 0,11409961 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 7,442E-03 0,11968974 GO:0090047|positive regulation of transcription regulator activity, ! tissue remodeling GO:0048771 62 36 1,000 7,442E-03 0,11885856 ! neural tube development GO:0021915 50 36 1,000 7,442E-03 0,11803885 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 7,442E-03 0,11723036 GO:0046660|female sex differentiation, ! gliogenesis GO:0042063 71 38 1,000 8,266E-03 0,12932572 ! striated muscle cell differentiation GO:0051146 54 38 1,000 8,266E-03 0,1284519 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 8,692E-03 0,13417651 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 8,692E-03 0,133282 ! cell growth GO:0016049 61 39 1,000 8,692E-03 0,13239934 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 9,129E-03 0,13813173 ! double-strand break repair GO:0006302 67 40 1,000 9,129E-03 0,13722891 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 9,129E-03 0,13633781 ! positive regulation of DNA binding GO:0043388 57 41 1,000 9,575E-03 0,14207667 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,01003031 0,14788277 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,01003031 0,14694084 ! positive regulation of binding GO:0051099 59 43 1,000 0,01049537 0,15278065 ! leukocyte migration GO:0050900 60 43 1,000 0,01049537 0,15181976 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01049537 0,15087089 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,01049537 0,1499338 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,01145363 0,16261327 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,01145363 0,16161565 ! histone modification GO:0016570 68 46 1,000 0,0119467 0,16754511 ! response to UV GO:0009411 75 46 1,000 0,0119467 0,16652969 ! covalent chromatin modification GO:0016569 75 47 1,000 0,01244895 0,1724855 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,01348077 0,18566329 ! cartilage development GO:0051216 70 49 1,000 0,01348077 0,18455815 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,01401019 0,19067118 ! lipid modification GO:0030258 73 50 1,000 0,01401019 0,18954959 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,01454852 0,19568183 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01454852 0,19454415 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 1,000 0,01454852 0,19341961 ! transition metal ion transport GO:0000041 74 52 1,000 0,0150957 0,1995408 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,0150957 0,19840057 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01621631 0,2119177 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01621631 0,21072042 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,01737149 0,22446304 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,01737149 0,22320905 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01789117 0,22860934 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01789117 0,2273463 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01789117 0,22609715 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01789117 0,22486164 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01789117 0,22363957 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01789117 0,22243071 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01789117 0,22123484 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01789117 0,22005177 ! sleep GO:0030431 11 5 0,000 0,01789117 0,21888128 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01789117 0,21772318 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01789117 0,21657727 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01789117 0,21544336 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01789117 0,21432126 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01789117 0,21321078 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01789117 0,21211176 ! tongue development GO:0043586 6 5 0,000 0,01789117 0,21102401 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01789117 0,20994735 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01789117 0,20888163 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01789117 0,20782667 ! cobalt ion transport GO:0006824 9 5 0,000 0,01789117 0,20678232 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01789117 0,20574841 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01789117 0,20472478 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01789117 0,20371129 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01789117 0,20270779 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01789117 0,20171412 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01789117 0,20073015 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01789117 0,19975573 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01789117 0,19879073 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01789117 0,197835 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01789117 0,19688843 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01789117 0,19595086 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01789117 0,19502218 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01789117 0,19410227 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01789117 0,19319099 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01789117 0,19228823 ! malate metabolic process GO:0006108 7 5 0,000 0,01789117 0,19139387 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01789117 0,19050778 ! behavioral response to pain GO:0048266 7 5 0,000 0,01789117 0,18962987 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01789117 0,18876 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01789117 0,18789809 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01789117 0,187044 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01789117 0,18619765 ! mating behavior GO:0007617 6 5 0,000 0,01789117 0,18535892 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01789117 0,18452772 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01789117 0,18370393 ! rhythmic behavior GO:0007622 12 5 0,000 0,01789117 0,18288747 ! copulation GO:0007620 7 5 0,000 0,01789117 0,18207823 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01789117 0,18127613 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01789117 0,18048106 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01789117 0,17969293 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01789117 0,17891166 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01789117 0,17813715 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01789117 0,17736931 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01789117 0,17660807 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01789117 0,17585334 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01789117 0,17510503 ! response to protozoan GO:0001562 9 5 0,000 0,01789117 0,17436306 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01789117 0,17362735 ! lymph vessel development GO:0001945 7 5 0,000 0,01789117 0,17289782 ! endochondral ossification GO:0001958 12 5 0,000 0,01789117 0,1721744 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01789117 0,171457 ! parathyroid gland development GO:0060017 8 5 0,000 0,01789117 0,17074556 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01789117 0,17004 ! anagen GO:0042640 6 5 0,000 0,01789117 0,16934025 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01789117 0,16864623 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01789117 0,16795788 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01789117 0,16727513 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01789117 0,1665979 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01789117 0,16592613 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01789117 0,16525976 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01789117 0,16459872 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01789117 0,16394295 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01789117 0,16329239 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01789117 0,16264696 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01789117 0,16200662 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01789117 0,1613713 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01789117 0,16074094 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01789117 0,16011549 ! ovulation GO:0030728 6 5 0,000 0,01789117 0,15949489 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01789117 0,15887908 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,01789117 0,158268 ! response to pH GO:0009268 9 5 0,000 0,01789117 0,15766161 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01789117 0,15705985 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01789117 0,15646267 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01789117 0,15587 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01789117 0,15528182 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01789117 0,15469805 ! polyol catabolic process GO:0046174 7 5 0,000 0,01789117 0,15411866 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01789117 0,15354359 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01789117 0,15297279 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01789117 0,15240623 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01789117 0,15184384 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01789117 0,15128559 ! urea metabolic process GO:0019627 6 5 0,000 0,01789117 0,15073143 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01789117 0,15018132 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01789117 0,1496352 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01789117 0,14909305 ! neutrophil activation GO:0042119 5 5 0,000 0,01789117 0,14855481 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01789117 0,14802044 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01789117 0,1474899 ! response to food GO:0032094 5 5 0,000 0,01789117 0,14696315 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01789117 0,14644015 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01789117 0,14592085 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01789117 0,14540523 ! forebrain neuron development GO:0021884 7 5 0,000 0,01789117 0,14489324 ! melanosome organization GO:0032438 7 5 0,000 0,01789117 0,14438485 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01789117 0,14388 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01789117 0,14337868 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01789117 0,14288084 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01789117 0,14238644 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01789117 0,14189545 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01789117 0,14140784 ! nucleoside transport GO:0015858 6 5 0,000 0,01789117 0,14092357 ! nucleoside salvage GO:0043174 7 5 0,000 0,01789117 0,1404426 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01789117 0,1399649 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01789117 0,13949044 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01789117 0,13901919 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01789117 0,13855111 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01789117 0,13808618 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01789117 0,13762435 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01789117 0,1371656 ! depyrimidination GO:0045008 8 5 0,000 0,01789117 0,1367099 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01789117 0,13625722 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01789117 0,13580753 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01789117 0,13536079 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01789117 0,13491699 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01789117 0,13447608 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01789117 0,13403805 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01789117 0,13360286 ! monocyte differentiation GO:0030224 8 5 0,000 0,01789117 0,13317049 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01789117 0,13274091 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01789117 0,13231409 ! centrosome duplication GO:0051298 5 5 0,000 0,01789117 0,13189 ! response to UV-C GO:0010225 6 5 0,000 0,01789117 0,13146863 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01789117 0,13104994 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01789117 0,13063391 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01789117 0,13022051 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01789117 0,12980972 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01789117 0,12940151 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01789117 0,12899587 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01789117 0,12859275 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01789117 0,12819215 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01789117 0,12779404 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01789117 0,12739839 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01789117 0,12700519 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01789117 0,1266144 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01789117 0,12622602 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01789117 0,12584 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01789117 0,12545634 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01789117 0,12507502 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01789117 0,124696 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01789117 0,12431928 ! neural tube patterning GO:0021532 6 5 0,000 0,01789117 0,12394482 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01789117 0,12357262 ! histone demethylation GO:0016577 9 5 0,000 0,01789117 0,12320264 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01789117 0,12283487 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01789117 0,12246929 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01789117 0,12210588 ! enteric nervous system development GO:0048484 8 5 0,000 0,01789117 0,12174462 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01789117 0,12138549 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01789117 0,12102847 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01789117 0,12067355 ! transcription termination GO:0006353 8 5 0,000 0,01789117 0,1203207 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01789117 0,11996992 ! plasminogen activation GO:0031639 5 5 0,000 0,01789117 0,11962117 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01789117 0,11927444 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01789117 0,11892971 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01789117 0,11858698 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01789117 0,11824621 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01789117 0,1179074 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01789117 0,11757052 ! apical protein localization GO:0045176 6 5 0,000 0,01789117 0,11723556 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01789117 0,1169025 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01789117 0,11657133 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01789117 0,11624204 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01789117 0,11591459 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01789117 0,11558899 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01789117 0,11526521 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01789117 0,11494324 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01789117 0,11462307 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01789117 0,11430467 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01789117 0,11398804 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01789117 0,11367315 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01789117 0,11336 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01789117 0,11304857 ! neural plate development GO:0001840 6 5 0,000 0,01789117 0,11273885 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01789117 0,11243082 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01789117 0,11212447 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01789117 0,11181979 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01789117 0,11151675 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01789117 0,11121535 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01789117 0,11091558 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01789117 0,11061742 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01789117 0,11032086 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01789117 0,11002589 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01789117 0,10973248 ! spindle assembly GO:0051225 5 5 0,000 0,01789117 0,10944064 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01789117 0,10915035 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01789117 0,10886159 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01789117 0,10857436 ! organ regeneration GO:0031100 7 5 0,000 0,01789117 0,10828863 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01789117 0,10800441 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01789117 0,10772168 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01789117 0,10744042 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01789117 0,10716063 GO:0055081|anion homeostasis, ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,01796187 0,10730466 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,01796187 0,10702667 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 1,000 0,01796187 0,10675012 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,01796187 0,10647499 ! developmental maturation GO:0021700 75 57 1,000 0,01796187 0,10620127 ! gonad development GO:0008406 79 57 1,000 0,01796187 0,10592896 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,01856069 0,10918051 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,01978338 0,11607593 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,01978338 0,11578057 GO:0035113|embryonic appendage morphogenesis, ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,02040711 0,11912783 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,02040711 0,11882624 ! extracellular matrix organization GO:0030198 103 61 1,000 0,02040711 0,11852617 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,02040711 0,11822762 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,02103903 0,12158233 ! tRNA transcription GO:0009304 11 6 0,000 0,02143141 0,12353946 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02143141 0,12323061 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02143141 0,1229233 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02143141 0,12261752 GO:0030816|positive regulation of cAMP metabolic process, ! regulation of helicase activity GO:0051095 11 6 0,000 0,02143141 0,12231326 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02143141 0,1220105 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02143141 0,12170924 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02143141 0,12140947 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02143141 0,12111116 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02143141 0,12081432 ! prostate gland development GO:0030850 9 6 0,000 0,02143141 0,12051893 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02143141 0,12022498 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02143141 0,11993247 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02143141 0,11964137 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02143141 0,11935168 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02143141 0,11906339 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02143141 0,11877649 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02143141 0,11849097 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02143141 0,11820682 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02143141 0,11792403 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02143141 0,11764259 ! neuron adhesion GO:0007158 9 6 0,000 0,02143141 0,11736249 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02143141 0,11708371 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02143141 0,11680627 ! signal peptide processing GO:0006465 8 6 0,000 0,02143141 0,11653013 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02143141 0,11625529 ! mRNA stabilization GO:0048255 15 6 0,000 0,02143141 0,11598175 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02143141 0,11570949 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02143141 0,11543851 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02143141 0,11516879 ! opsonization GO:0008228 8 6 0,000 0,02143141 0,11490034 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02143141 0,11463313 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02143141 0,11436716 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02143141 0,11410242 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02143141 0,1138389 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02143141 0,1135766 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02143141 0,1133155 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02143141 0,11305561 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02143141 0,1127969 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02143141 0,11253937 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02143141 0,11228302 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02143141 0,11202783 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02143141 0,1117738 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02143141 0,11152091 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02143141 0,11126917 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02143141 0,11101857 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02143141 0,11076909 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02143141 0,11052073 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02143141 0,11027348 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02143141 0,11002733 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02143141 0,10978228 ! thymic T cell selection GO:0045061 12 6 0,000 0,02143141 0,10953832 ! protein lipoylation GO:0009249 10 6 0,000 0,02143141 0,10929544 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02143141 0,10905364 ! pigment granule organization GO:0048753 11 6 0,000 0,02143141 0,1088129 ! drug transport GO:0015893 6 6 0,000 0,02143141 0,10857322 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02143141 0,1083346 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02143141 0,10809703 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02143141 0,10786049 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02143141 0,10762499 ! histidine metabolic process GO:0006547 6 6 0,000 0,02143141 0,10739051 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02143141 0,10715705 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02143141 0,10692461 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02143141 0,10669317 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02143141 0,10646273 ! adenohypophysis development GO:0021984 10 6 0,000 0,02143141 0,10623328 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02143141 0,10600483 ! hyperosmotic response GO:0006972 8 6 0,000 0,02143141 0,10577735 ! microtubule nucleation GO:0007020 10 6 0,000 0,02143141 0,10555084 ! ER overload response GO:0006983 7 6 0,000 0,02143141 0,10532531 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02143141 0,10510073 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02143141 0,10487711 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02143141 0,10465445 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02143141 0,10443272 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02143141 0,10421193 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02143141 0,10399208 ! response to dietary excess GO:0002021 7 6 0,000 0,02143141 0,10377314 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02143141 0,10355513 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02143141 0,10333804 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02143141 0,10312185 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02143141 0,10290656 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02143141 0,10269217 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02143141 0,10247868 ! neuron apoptosis GO:0051402 8 6 0,000 0,02143141 0,10226607 ! organic alcohol transport GO:0015850 9 6 0,000 0,02143141 0,10205434 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02143141 0,10184348 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02143141 0,10163349 ! male sex determination GO:0030238 9 6 0,000 0,02143141 0,10142437 ! carnitine transport GO:0015879 8 6 0,000 0,02143141 0,10121611 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02143141 0,1010087 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02143141 0,10080213 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02143141 0,10059642 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02143141 0,10039154 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02143141 0,10018749 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02143141 0,09998427 ! parturition GO:0007567 12 6 0,000 0,02143141 0,09978187 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02143141 0,09958029 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02143141 0,09937952 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02143141 0,09917957 ! spindle checkpoint GO:0031577 14 6 0,000 0,02143141 0,09898041 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02143141 0,09878205 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02143141 0,09858449 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02143141 0,09838771 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02143141 0,09819172 ! astrocyte development GO:0014002 14 6 0,000 0,02143141 0,09799651 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02143141 0,09780207 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02143141 0,0976084 ! interaction with symbiont GO:0051702 8 6 0,000 0,02143141 0,0974155 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02143141 0,09722336 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02143141 0,09703198 ! eating behavior GO:0042755 6 6 0,000 0,02143141 0,09684134 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02143141 0,09665146 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02143141 0,09646232 ! response to copper ion GO:0046688 9 6 0,000 0,02143141 0,09627391 ! DNA topological change GO:0006265 8 6 0,000 0,02143141 0,09608625 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02143141 0,09589931 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02143141 0,09571309 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02143141 0,0955276 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02143141 0,09534283 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02143141 0,09515877 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02143141 0,09497542 ! gas homeostasis GO:0033483 11 6 0,000 0,02143141 0,09479278 ! hair follicle maturation GO:0048820 7 6 0,000 0,02143141 0,09461083 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02143141 0,09442959 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02143141 0,09424903 ! Schwann cell development GO:0014044 14 6 0,000 0,02143141 0,09406917 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02143141 0,09388999 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02143141 0,09371149 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02143141 0,09353367 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02143141 0,09335652 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02143141 0,09318005 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02143141 0,09300423 ! histone ubiquitination GO:0016574 7 6 0,000 0,02143141 0,09282908 ! regulation of meiosis GO:0040020 10 6 0,000 0,02143141 0,09265459 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02143141 0,09248076 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02143141 0,09230757 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02143141 0,09213504 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02143141 0,09196314 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02143141 0,09179189 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02143141 0,09162127 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02143141 0,09145129 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02143141 0,09128193 ! receptor internalization GO:0031623 9 6 0,000 0,02143141 0,0911132 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02143141 0,0909451 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02143141 0,09077761 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02143141 0,09061074 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02143141 0,09044448 ! protein deubiquitination GO:0016579 8 6 0,000 0,02143141 0,09027883 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02143141 0,09011379 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02143141 0,08994935 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02143141 0,08978551 ! axonal fasciculation GO:0007413 9 6 0,000 0,02143141 0,08962226 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02143141 0,08945961 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02143141 0,08929754 ! midbrain development GO:0030901 6 6 0,000 0,02143141 0,08913606 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02143141 0,08897517 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02143141 0,08881485 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02143141 0,08865511 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02143141 0,08849595 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02143141 0,08833735 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02143141 0,08817933 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02143141 0,08802186 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02143141 0,08786496 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02143141 0,08770862 ! adult feeding behavior GO:0008343 6 6 0,000 0,02143141 0,08755283 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02143141 0,0873976 ! blastocyst growth GO:0001832 15 6 0,000 0,02143141 0,08724291 ! pigment granule transport GO:0051904 12 6 0,000 0,02143141 0,08708877 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02143141 0,08693517 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02143141 0,08678212 ! catecholamine transport GO:0051937 7 6 0,000 0,02143141 0,0866296 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02143141 0,08647762 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02143141 0,08632617 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02143141 0,08617525 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02143141 0,08602486 ! protein prenylation GO:0018342 10 6 0,000 0,02143141 0,08587499 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02143141 0,08572564 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02143141 0,08557681 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02143141 0,0854285 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02143141 0,0852807 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02143141 0,08513341 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02167905 0,08596866 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,02167905 0,08582069 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02167905 0,08567323 ! negative regulation of cell size GO:0045792 108 64 1,000 0,02232712 0,08808299 ! appendage morphogenesis GO:0035107 93 64 1,000 0,02232712 0,08793216 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 90 65 1,000 0,02298317 0,09036119 ! appendage development GO:0048736 94 65 1,000 0,02298317 0,09020699 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 1,000 0,02298317 0,09005332 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,02431896 0,09512519 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0249591 0,09746336 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0249591 0,09729817 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0249591 0,09713353 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0249591 0,09696946 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0249591 0,09680593 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0249591 0,09664296 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0249591 0,09648054 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0249591 0,09631866 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0249591 0,09615732 ! reproductive behavior GO:0019098 12 7 0,000 0,0249591 0,09599652 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0249591 0,09583626 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0249591 0,09567653 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0249591 0,09551734 ! oligopeptide transport GO:0006857 11 7 0,000 0,0249591 0,09535867 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0249591 0,09520053 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0249591 0,09504291 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0249591 0,09488582 ! RNA methylation GO:0001510 11 7 0,000 0,0249591 0,09472924 ! pericardium development GO:0060039 8 7 0,000 0,0249591 0,09457318 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0249591 0,09441763 ! fibril organization GO:0043206 13 7 0,000 0,0249591 0,09426259 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0249591 0,09410806 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0249591 0,09395404 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0249591 0,09380052 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0249591 0,0936475 ! lipoprotein transport GO:0042953 9 7 0,000 0,0249591 0,09349498 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0249591 0,09334296 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0249591 0,09319143 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0249591 0,09304039 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0249591 0,09288984 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0249591 0,09273977 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0249591 0,09259019 ! chemosensory behavior GO:0007635 9 7 0,000 0,0249591 0,09244109 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0249591 0,09229247 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0249591 0,09214433 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0249591 0,09199667 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0249591 0,09184947 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0249591 0,09170275 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0249591 0,09155649 ! reflex GO:0060004 12 7 0,000 0,0249591 0,0914107 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0249591 0,09126537 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0249591 0,09112051 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0249591 0,0909761 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0249591 0,09083215 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0249591 0,09068866 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0249591 0,09054561 ! spinal cord patterning GO:0021511 7 7 0,000 0,0249591 0,09040302 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0249591 0,09026088 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0249591 0,09011918 ! adrenal gland development GO:0030325 17 7 0,000 0,0249591 0,08997793 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0249591 0,08983712 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0249591 0,08969675 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0249591 0,08955682 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0249591 0,08941732 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0249591 0,08927826 ! endosome organization GO:0007032 10 7 0,000 0,0249591 0,08913963 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0249591 0,08900142 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0249591 0,08886365 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0249591 0,0887263 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0249591 0,08858938 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0249591 0,08845288 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0249591 0,0883168 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0249591 0,08818114 ! galactose metabolic process GO:0006012 10 7 0,000 0,0249591 0,08804589 ! vesicle fusion GO:0006906 15 7 0,000 0,0249591 0,08791106 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0249591 0,08777663 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0249591 0,08764262 ! organ growth GO:0035265 11 7 0,000 0,0249591 0,08750902 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0249591 0,08737583 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0249591 0,08724304 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0249591 0,08711065 ! retinol metabolic process GO:0042572 9 7 0,000 0,0249591 0,08697867 ! behavioral fear response GO:0001662 13 7 0,000 0,0249591 0,08684708 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0249591 0,08671589 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0249591 0,0865851 ! rRNA modification GO:0000154 12 7 0,000 0,0249591 0,0864547 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0249591 0,08632469 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0249591 0,08619507 ! response to UV-B GO:0010224 11 7 0,000 0,0249591 0,08606585 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0249591 0,085937 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0249591 0,08580855 ! intermediate filament organization GO:0045109 11 7 0,000 0,0249591 0,08568048 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0249591 0,08555279 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0249591 0,08542547 ! fibrinolysis GO:0042730 9 7 0,000 0,0249591 0,08529854 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0249591 0,08517199 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0249591 0,08504581 ! B cell lineage commitment GO:0002326 17 7 0,000 0,0249591 0,08492 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0249591 0,08479456 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0249591 0,0846695 ! response to tropane GO:0014073 13 7 0,000 0,0249591 0,0845448 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0249591 0,08442047 ! melanosome localization GO:0032400 10 7 0,000 0,0249591 0,0842965 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0249591 0,0841729 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0249591 0,08404966 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0249591 0,08392678 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0249591 0,08380426 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0249591 0,0836821 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0249591 0,08356029 ! mast cell activation GO:0045576 9 7 0,000 0,0249591 0,08343884 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0249591 0,08331773 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0249591 0,08319698 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0249591 0,08307658 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0249591 0,08295653 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0249591 0,08283682 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0249591 0,08271746 ! T cell lineage commitment GO:0002360 12 7 0,000 0,0249591 0,08259844 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0249591 0,08247977 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0249591 0,08236143 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0249591 0,08224344 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0249591 0,08212578 ! response to tumor cell GO:0002347 12 7 0,000 0,0249591 0,08200846 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0249591 0,08189147 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0249591 0,08177481 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0249591 0,08165849 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0249591 0,0815425 ! diuresis GO:0030146 12 7 0,000 0,0249591 0,08142684 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0249591 0,0813115 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0249591 0,08119649 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0249591 0,08108181 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0249591 0,08096745 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0249591 0,08085341 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0249591 0,08073969 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0249591 0,08062629 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0249591 0,08051321 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0249591 0,08040045 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0249591 0,080288 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0249591 0,08017586 ! lymph node development GO:0048535 9 7 0,000 0,0249591 0,08006404 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0249591 0,07995253 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0249591 0,07984133 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0249591 0,07973044 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0249591 0,07961986 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0249591 0,07950958 ! ATP catabolic process GO:0006200 10 7 0,000 0,0249591 0,07939961 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0249591 0,07928994 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0249591 0,07918058 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0249591 0,07907151 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0249591 0,07896275 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0249591 0,07885428 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0249591 0,07874612 ! muscle adaptation GO:0043500 12 7 0,000 0,0249591 0,07863825 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0249591 0,07853067 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0249591 0,07842339 ! retina homeostasis GO:0001895 9 7 0,000 0,0249591 0,0783164 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0249591 0,0782097 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0249591 0,07810329 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0249591 0,07799717 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0249591 0,07789134 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0249591 0,0777858 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0249591 0,07768054 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0249591 0,07757557 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,02499857 0,07759341 ! rhythmic process GO:0048511 105 68 1,000 0,02499857 0,07748884 ! humoral immune response GO:0006959 86 70 1,000 0,02638092 0,08166367 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,02638092 0,08155391 ! muscle cell differentiation GO:0042692 104 71 1,000 0,02708352 0,08361356 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,02779367 0,08569093 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,02779367 0,08557622 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02847426 0,08755456 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02847426 0,08743766 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02847426 0,08732108 ! axon extension GO:0048675 11 8 0,000 0,02847426 0,0872048 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02847426 0,08708884 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02847426 0,08697318 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02847426 0,08685784 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02847426 0,08674279 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02847426 0,08662805 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02847426 0,08651362 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02847426 0,08639948 ! phosphate transport GO:0006817 10 8 0,000 0,02847426 0,08628565 ! N-glycan processing GO:0006491 12 8 0,000 0,02847426 0,08617212 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02847426 0,08605888 ! UTP metabolic process GO:0046051 8 8 0,000 0,02847426 0,08594594 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02847426 0,0858333 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02847426 0,08572095 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02847426 0,0856089 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02847426 0,08549714 ! succinate metabolic process GO:0006105 14 8 0,000 0,02847426 0,08538567 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02847426 0,08527449 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02847426 0,0851636 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02847426 0,085053 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02847426 0,08494268 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02847426 0,08483265 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02847426 0,08472291 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02847426 0,08461345 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02847426 0,08450427 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02847426 0,08439537 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02847426 0,08428675 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02847426 0,08417842 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02847426 0,08407036 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02847426 0,08396257 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02847426 0,08385507 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02847426 0,08374784 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02847426 0,08364088 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02847426 0,08353419 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02847426 0,08342778 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02847426 0,08332164 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02847426 0,08321577 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02847426 0,08311016 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02847426 0,08300483 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02847426 0,08289976 ! melanin metabolic process GO:0006582 12 8 0,000 0,02847426 0,08279495 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02847426 0,08269041 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02847426 0,08258614 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02847426 0,08248213 ! macrophage activation GO:0042116 12 8 0,000 0,02847426 0,08237837 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02847426 0,08227488 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02847426 0,08217165 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02847426 0,08206868 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02847426 0,08196597 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02847426 0,08186351 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02847426 0,08176131 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02847426 0,08165936 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02847426 0,08155767 ! ruffle organization GO:0031529 11 8 0,000 0,02847426 0,08145623 ! osteoblast development GO:0002076 13 8 0,000 0,02847426 0,08135504 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02847426 0,0812541 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02847426 0,08115342 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02847426 0,08105298 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02847426 0,08095279 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02847426 0,08085285 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02847426 0,08075315 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02847426 0,0806537 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02847426 0,0805545 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02847426 0,08045554 ! brain morphogenesis GO:0048854 20 8 0,000 0,02847426 0,08035682 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02847426 0,08025834 ! segment specification GO:0007379 10 8 0,000 0,02847426 0,08016011 ! cellular extravasation GO:0045123 11 8 0,000 0,02847426 0,08006211 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02847426 0,07996436 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02847426 0,07986684 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02847426 0,07976956 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02847426 0,07967252 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02847426 0,07957571 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02847426 0,07947914 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02847426 0,0793828 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02847426 0,07928669 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02847426 0,07919082 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02847426 0,07909518 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02847426 0,07899977 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02847426 0,07890459 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02847426 0,07880964 ! icosanoid secretion GO:0032309 12 8 0,000 0,02847426 0,07871491 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02847426 0,07862042 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02847426 0,07852615 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02847426 0,0784321 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02847426 0,07833829 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02847426 0,07824469 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02847426 0,07815132 ! sterol catabolic process GO:0016127 9 8 0,000 0,02847426 0,07805817 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02847426 0,07796525 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02847426 0,07787254 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02847426 0,07778006 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02847426 0,07768779 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02847426 0,07759574 ! prophase GO:0051324 11 8 0,000 0,02847426 0,07750391 ! S phase GO:0051320 8 8 0,000 0,02847426 0,0774123 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02847426 0,07732091 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02847426 0,07722973 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02847426 0,07713876 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02847426 0,07704801 ! hormone catabolic process GO:0042447 13 8 0,000 0,02847426 0,07695747 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02847426 0,07686715 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02847426 0,07677703 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02847426 0,07668713 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02847426 0,07659744 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02847426 0,07650795 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02847426 0,07641868 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02847426 0,07632961 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02847426 0,07624075 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02847426 0,0761521 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02847426 0,07606366 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02847426 0,07597541 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02847426 0,07588738 ! regulation of embryonic development GO:0045995 16 8 0,000 0,02847426 0,07579955 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02847426 0,07571192 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02847426 0,07562449 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02847426 0,07553726 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,02923634 0,07746955 ! negative regulation of growth GO:0045926 123 75 1,000 0,02996874 0,07931886 ! regulation of DNA binding GO:0051101 119 77 1,000 0,03145536 0,08315785 ! sex differentiation GO:0007548 105 77 1,000 0,03145536 0,08306238 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03197696 0,0843429 ! regulation of developmental growth GO:0048638 13 9 0,000 0,03197696 0,08424629 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,03197696 0,0841499 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03197696 0,08405373 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03197696 0,08395777 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03197696 0,08386204 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03197696 0,08376653 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03197696 0,08367123 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03197696 0,08357615 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03197696 0,08348128 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03197696 0,08338663 ! GTP metabolic process GO:0046039 9 9 0,000 0,03197696 0,0832922 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03197696 0,08319798 ! social behavior GO:0035176 14 9 0,000 0,03197696 0,08310397 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03197696 0,08301017 ! artery development GO:0060840 19 9 0,000 0,03197696 0,08291658 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03197696 0,08282321 ! regulation of glycolysis GO:0006110 15 9 0,000 0,03197696 0,08273004 ! response to pain GO:0048265 16 9 0,000 0,03197696 0,08263709 ! protein complex disassembly GO:0043241 17 9 0,000 0,03197696 0,08254434 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03197696 0,0824518 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03197696 0,08235947 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03197696 0,08226735 ! lung alveolus development GO:0048286 17 9 0,000 0,03197696 0,08217543 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03197696 0,08208372 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03197696 0,08199221 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03197696 0,0819009 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03197696 0,0818098 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03197696 0,0817189 ! protein targeting to ER GO:0045047 19 9 0,000 0,03197696 0,0816282 ! T cell selection GO:0045058 18 9 0,000 0,03197696 0,08153771 ! endoderm development GO:0007492 12 9 0,000 0,03197696 0,08144741 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03197696 0,08135731 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03197696 0,08126741 ! arginine catabolic process GO:0006527 10 9 0,000 0,03197696 0,08117772 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03197696 0,08108821 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03197696 0,08099891 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03197696 0,0809098 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03197696 0,08082089 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03197696 0,08073217 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03197696 0,08064365 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03197696 0,08055532 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03197696 0,08046719 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03197696 0,08037925 ! mannose metabolic process GO:0006013 9 9 0,000 0,03197696 0,0802915 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03197696 0,08020394 ! receptor clustering GO:0043113 15 9 0,000 0,03197696 0,08011657 ! epithelial cell development GO:0002064 10 9 0,000 0,03197696 0,08002939 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03197696 0,0799424 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03197696 0,0798556 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03197696 0,07976899 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03197696 0,07968257 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03197696 0,07959633 ! motor axon guidance GO:0008045 14 9 0,000 0,03197696 0,07951028 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03197696 0,07942442 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03197696 0,07933874 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03197696 0,07925324 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03197696 0,07916793 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03197696 0,07908281 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03197696 0,07899786 ! DNA ligation GO:0006266 14 9 0,000 0,03197696 0,0789131 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03197696 0,07882852 ! response to amine stimulus GO:0014075 13 9 0,000 0,03197696 0,07874412 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03197696 0,0786599 ! erythrocyte development GO:0048821 11 9 0,000 0,03197696 0,07857587 ! renal water homeostasis GO:0003091 14 9 0,000 0,03197696 0,07849201 ! mRNA cleavage GO:0006379 13 9 0,000 0,03197696 0,07840833 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03197696 0,07832482 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03197696 0,0782415 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03197696 0,07815835 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03197696 0,07807538 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03197696 0,07799259 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03197696 0,07790997 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03197696 0,07782752 ! acid secretion GO:0046717 14 9 0,000 0,03197696 0,07774525 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03197696 0,07766316 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03197696 0,07758123 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03197696 0,07749948 ! purine base metabolic process GO:0006144 18 9 0,000 0,03197696 0,07741791 ! oocyte differentiation GO:0009994 12 9 0,000 0,03197696 0,0773365 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03197696 0,07725526 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03197696 0,0771742 ! spleen development GO:0048536 15 9 0,000 0,03197696 0,0770933 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03197696 0,07701258 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03197696 0,07693202 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03197696 0,07685163 ! detection of calcium ion GO:0005513 13 9 0,000 0,03197696 0,07677141 ! blastocyst formation GO:0001825 12 9 0,000 0,03197696 0,07669136 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03197696 0,07661147 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03197696 0,07653175 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03197696 0,07645219 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03197696 0,0763728 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03197696 0,07629358 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03197696 0,07621452 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03197696 0,07613562 ! prepulse inhibition GO:0060134 14 9 0,000 0,03197696 0,07605689 ! embryonic placenta development GO:0001892 12 9 0,000 0,03197696 0,07597832 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03197696 0,07589991 ! insulin secretion GO:0030073 17 9 0,000 0,03197696 0,07582166 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03197696 0,07574357 ! response to nicotine GO:0035094 16 9 0,000 0,03197696 0,07566565 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03197696 0,07558788 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03197696 0,07551028 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,03220947 0,07598131 ! forebrain development GO:0030900 131 80 1,000 0,03373897 0,07950782 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,03451425 0,08125156 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03546723 0,08340964 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03546723 0,08332444 ! neuron fate specification GO:0048665 11 10 0,000 0,03546723 0,08323941 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03546723 0,08315456 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03546723 0,08306988 ! thyroid gland development GO:0030878 19 10 0,000 0,03546723 0,08298538 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03546723 0,08290104 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03546723 0,08281688 ! synapsis GO:0007129 13 10 0,000 0,03546723 0,08273289 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03546723 0,08264906 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03546723 0,08256541 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03546723 0,08248193 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03546723 0,08239861 ! sulfate transport GO:0008272 12 10 0,000 0,03546723 0,08231547 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03546723 0,08223249 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,03546723 0,08214967 ! phospholipid efflux GO:0033700 16 10 0,000 0,03546723 0,08206703 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,03546723 0,08198455 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03546723 0,08190224 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03546723 0,08182009 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03546723 0,0817381 ! pathogenesis GO:0009405 13 10 0,000 0,03546723 0,08165628 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03546723 0,08157463 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03546723 0,08149313 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03546723 0,0814118 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03546723 0,08133063 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03546723 0,08124963 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03546723 0,08116878 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03546723 0,0810881 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03546723 0,08100757 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03546723 0,08092721 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03546723 0,080847 ! response to X-ray GO:0010165 16 10 0,000 0,03546723 0,08076696 ! B cell proliferation GO:0042100 14 10 0,000 0,03546723 0,08068707 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03546723 0,08060734 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03546723 0,08052777 ! forebrain cell migration GO:0021885 17 10 0,000 0,03546723 0,08044835 ! lipid digestion GO:0044241 15 10 0,000 0,03546723 0,08036909 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03546723 0,08028999 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03546723 0,08021104 ! UV protection GO:0009650 14 10 0,000 0,03546723 0,08013225 ! entry into host cell GO:0030260 20 10 0,000 0,03546723 0,08005361 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03546723 0,07997512 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03546723 0,07989679 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03546723 0,07981862 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03546723 0,07974059 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03546723 0,07966272 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03546723 0,079585 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03546723 0,07950743 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03546723 0,07943002 ! regulation of organ growth GO:0046620 11 10 0,000 0,03546723 0,07935275 ! response to dsRNA GO:0043331 18 10 0,000 0,03546723 0,07927563 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03546723 0,07919867 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03546723 0,07912185 ! embryonic axis specification GO:0000578 12 10 0,000 0,03546723 0,07904518 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03546723 0,07896866 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03546723 0,07889229 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03546723 0,07881606 ! cranial nerve development GO:0021545 12 10 0,000 0,03546723 0,07873999 ! fucose catabolic process GO:0019317 16 10 0,000 0,03546723 0,07866406 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03546723 0,07858827 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03546723 0,07851263 ! protein sumoylation GO:0016925 12 10 0,000 0,03546723 0,07843714 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03546723 0,07836179 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03546723 0,07828659 ! salivary gland development GO:0007431 22 10 0,000 0,03546723 0,07821153 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03546723 0,07813662 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03546723 0,07806184 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03546723 0,07798721 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03546723 0,07791273 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03546723 0,07783838 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03546723 0,07776418 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03546723 0,07769012 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03546723 0,0776162 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03546723 0,07754242 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,03546723 0,07746878 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03546723 0,07739528 ! detection of bacterium GO:0016045 10 10 0,000 0,03546723 0,07732192 ! embryonic gut development GO:0048566 11 10 0,000 0,03546723 0,0772487 ! activation of innate immune response GO:0002218 10 10 0,000 0,03546723 0,07717562 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03546723 0,07710267 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03546723 0,07702986 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03546723 0,07695719 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03546723 0,07688466 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03546723 0,07681227 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03546723 0,07674001 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,03608557 0,07800451 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,03688149 0,07965016 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,03768417 0,08130731 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,03768417 0,08123111 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,03768417 0,08115505 ! cell cycle arrest GO:0007050 150 86 1,000 0,03849357 0,08282058 ! rRNA transcription GO:0009303 17 11 0,000 0,03894511 0,08371379 ! respiratory burst GO:0045730 14 11 0,000 0,03894511 0,08363563 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03894511 0,08355761 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03894511 0,08347974 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03894511 0,08340201 ! virus-host interaction GO:0019048 17 11 0,000 0,03894511 0,08332442 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03894511 0,08324699 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03894511 0,08316969 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03894511 0,08309254 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03894511 0,08301553 ! mating GO:0007618 14 11 0,000 0,03894511 0,08293866 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03894511 0,08286194 ! T cell proliferation GO:0042098 20 11 0,000 0,03894511 0,08278536 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03894511 0,08270892 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03894511 0,08263262 ! bone resorption GO:0045453 16 11 0,000 0,03894511 0,08255646 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03894511 0,08248044 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03894511 0,08240456 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03894511 0,08232882 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03894511 0,08225322 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03894511 0,08217776 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03894511 0,08210243 ! syncytium formation GO:0006949 15 11 0,000 0,03894511 0,08202725 ! plasma membrane organization GO:0007009 18 11 0,000 0,03894511 0,0819522 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03894511 0,08187729 ! focal adhesion formation GO:0048041 24 11 0,000 0,03894511 0,08180252 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03894511 0,08172788 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03894511 0,08165338 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03894511 0,08157901 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03894511 0,08150478 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03894511 0,08143069 ! adult heart development GO:0007512 11 11 0,000 0,03894511 0,08135673 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03894511 0,0812829 ! temperature homeostasis GO:0001659 16 11 0,000 0,03894511 0,08120921 ! L-glutamate transport GO:0015813 16 11 0,000 0,03894511 0,08113565 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03894511 0,08106222 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03894511 0,08098893 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03894511 0,08091577 ! stem cell development GO:0048864 29 11 0,000 0,03894511 0,08084274 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03894511 0,08076984 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03894511 0,08069708 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03894511 0,08062444 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03894511 0,08055194 ! vasoconstriction GO:0042310 15 11 0,000 0,03894511 0,08047957 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03894511 0,08040732 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03894511 0,08033521 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03894511 0,08026322 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03894511 0,08019137 ! ribosome assembly GO:0042255 13 11 0,000 0,03894511 0,08011964 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03894511 0,08004804 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03894511 0,07997657 ! chromatin silencing GO:0006342 19 11 0,000 0,03894511 0,07990522 ! nucleosome positioning GO:0016584 13 11 0,000 0,03894511 0,07983401 ! T cell homeostasis GO:0043029 20 11 0,000 0,03894511 0,07976292 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03894511 0,07969195 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03894511 0,07962112 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03894511 0,07955041 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03894511 0,07947982 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03894511 0,07940936 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03894511 0,07933902 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03894511 0,07926881 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03894511 0,07919872 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03894511 0,07912876 ! male genitalia development GO:0030539 13 11 0,000 0,03894511 0,07905892 ! cholesterol efflux GO:0033344 19 11 0,000 0,03894511 0,0789892 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03894511 0,07891961 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03894511 0,07885014 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03894511 0,07878079 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03894511 0,07871156 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03894511 0,07864245 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03894511 0,07857347 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,03894511 0,07850461 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,03894511 0,07843586 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03894511 0,07836724 ! lysogeny GO:0030069 18 11 0,000 0,03894511 0,07829874 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03894511 0,07823035 ! acrosome reaction GO:0007340 13 11 0,000 0,03894511 0,07816209 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03894511 0,07809395 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,03930961 0,07875619 GO:0060538|skeletal muscle organ development, ! protein processing GO:0016485 114 88 1,000 0,04013225 0,08033436 ! reproductive developmental process GO:0003006 127 89 1,000 0,04096143 0,08192285 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,04096143 0,08185168 ! lactation GO:0007595 20 12 0,000 0,04241065 0,08467404 ! reproductive cellular process GO:0048610 14 12 0,000 0,04241065 0,08460061 ! tRNA modification GO:0006400 14 12 0,000 0,04241065 0,0845273 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04241065 0,08445411 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04241065 0,08438105 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,04241065 0,08430812 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04241065 0,08423532 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04241065 0,08416264 ! non-recombinational repair GO:0000726 19 12 0,000 0,04241065 0,08409009 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04241065 0,08401766 ! peroxisomal transport GO:0043574 21 12 0,000 0,04241065 0,08394535 ! cartilage condensation GO:0001502 18 12 0,000 0,04241065 0,08387317 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04241065 0,08380112 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04241065 0,08372918 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04241065 0,08365737 ! heart looping GO:0001947 15 12 0,000 0,04241065 0,08358569 ! palate development GO:0060021 15 12 0,000 0,04241065 0,08351413 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04241065 0,08344269 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04241065 0,08337137 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04241065 0,08330017 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04241065 0,08322909 ! arginine metabolic process GO:0006525 13 12 0,000 0,04241065 0,08315814 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04241065 0,08308731 ! methionine metabolic process GO:0006555 13 12 0,000 0,04241065 0,0830166 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04241065 0,082946 ! Golgi organization GO:0007030 18 12 0,000 0,04241065 0,08287553 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04241065 0,08280518 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04241065 0,08273494 ! monoamine transport GO:0015844 13 12 0,000 0,04241065 0,08266483 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04241065 0,08259483 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,04241065 0,08252496 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04241065 0,0824552 ! L-amino acid transport GO:0015807 20 12 0,000 0,04241065 0,08238556 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04241065 0,08231603 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04241065 0,08224663 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04241065 0,08217734 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04241065 0,08210816 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04241065 0,08203911 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04241065 0,08197017 ! cerebellum development GO:0021549 13 12 0,000 0,04241065 0,08190134 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04241065 0,08183263 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04241065 0,08176404 ! histone methylation GO:0016571 15 12 0,000 0,04241065 0,08169556 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04241065 0,0816272 ! gland morphogenesis GO:0022612 23 12 0,000 0,04241065 0,08155895 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04241065 0,08149081 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04241065 0,08142279 ! response to gamma radiation GO:0010332 20 12 0,000 0,04241065 0,08135488 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04241065 0,08128708 ! intestinal absorption GO:0050892 19 12 0,000 0,04241065 0,0812194 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04241065 0,08115183 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04241065 0,08108437 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,04241065 0,08101703 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04241065 0,08094979 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,04241065 0,08088267 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04241065 0,08081566 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04241065 0,08074876 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04241065 0,08068197 ! response to cold GO:0009409 14 12 0,000 0,04241065 0,08061529 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,04348762 0,08259416 ! cell fate commitment GO:0045165 141 92 1,000 0,04348762 0,08252601 ! DNA recombination GO:0006310 146 92 1,000 0,04348762 0,08245798 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,04434239 0,08400946 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,04434239 0,08394032 ! response to oxidative stress GO:0006979 141 94 1,000 0,04520341 0,08549988 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04586389 0,08667786 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04586389 0,0866067 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04586389 0,08653565 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04586389 0,08646472 ! water transport GO:0006833 17 13 0,000 0,04586389 0,0863939 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04586389 0,0863232 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04586389 0,08625262 ! lipid localization GO:0010876 24 13 0,000 0,04586389 0,08618215 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04586389 0,0861118 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04586389 0,08604156 ! organelle fusion GO:0048284 28 13 0,000 0,04586389 0,08597144 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04586389 0,08590143 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04586389 0,08583153 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04586389 0,08576175 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04586389 0,08569208 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04586389 0,08562253 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04586389 0,08555309 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04586389 0,08548376 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04586389 0,08541454 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04586389 0,08534543 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04586389 0,08527644 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04586389 0,08520756 ! NAD metabolic process GO:0019674 21 13 0,000 0,04586389 0,08513879 ! exocrine system development GO:0035272 27 13 0,000 0,04586389 0,08507012 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04586389 0,08500158 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04586389 0,08493314 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04586389 0,08486481 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04586389 0,08479659 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04586389 0,08472848 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04586389 0,08466048 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,04586389 0,08459259 ! genitalia development GO:0048806 15 13 0,000 0,04586389 0,0845248 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04586389 0,08445713 ! cellular pigmentation GO:0033059 24 13 0,000 0,04586389 0,08438956 ! tissue regeneration GO:0042246 21 13 0,000 0,04586389 0,08432211 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04586389 0,08425476 ! cofactor transport GO:0051181 19 13 0,000 0,04586389 0,08418751 ! NADP metabolic process GO:0006739 18 13 0,000 0,04586389 0,08412038 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04586389 0,08405335 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04586389 0,08398643 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04586389 0,08391961 ! gas transport GO:0015669 18 13 0,000 0,04586389 0,08385291 ! regulation of RNA stability GO:0043487 28 13 0,000 0,04586389 0,0837863 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04586389 0,08371981 ! regulation of axon extension GO:0030516 23 13 0,000 0,04586389 0,08365341 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04586389 0,08358713 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04586389 0,08352095 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04586389 0,08345487 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04586389 0,0833889 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04586389 0,08332303 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04586389 0,08325726 ! regulation of binding GO:0051098 151 95 1,000 0,04607065 0,08356663 ! protein maturation GO:0051604 129 96 1,000 0,04694403 0,08508374 ! response to light stimulus GO:0009416 153 96 1,000 0,04694403 0,08501675 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04930488 0,08922205 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,04930488 0,0891519 ! superoxide anion generation GO:0042554 18 14 0,000 0,04930488 0,08908187 ! neuron maturation GO:0042551 21 14 0,000 0,04930488 0,08901195 ! regulation of S phase GO:0033261 18 14 0,000 0,04930488 0,08894213 ! myotube differentiation GO:0014902 21 14 0,000 0,04930488 0,08887243 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,04930488 0,08880284 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04930488 0,08873335 ! inositol metabolic process GO:0006020 20 14 0,000 0,04930488 0,08866397 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04930488 0,0885947 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04930488 0,08852554 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04930488 0,08845649 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04930488 0,08838755 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04930488 0,08831871 ! response to cAMP GO:0051591 19 14 0,000 0,04930488 0,08824998 ! startle response GO:0001964 21 14 0,000 0,04930488 0,08818135 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04930488 0,08811284 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04930488 0,08804443 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04930488 0,08797612 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04930488 0,08790792 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04930488 0,08783983 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04930488 0,08777184 ! glycine metabolic process GO:0006544 22 14 0,000 0,04930488 0,08770396 ! pituitary gland development GO:0021983 23 14 0,000 0,04930488 0,08763618 ! cellular response to starvation GO:0009267 21 14 0,000 0,04930488 0,08756851 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04930488 0,08750094 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04930488 0,08743348 ! regulation of heart rate GO:0002027 23 14 0,000 0,04930488 0,08736612 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04930488 0,08729886 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04930488 0,08723171 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04930488 0,08716466 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04930488 0,08709771 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,04930488 0,08703087 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,04930488 0,08696413 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04930488 0,08689749 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04930488 0,08683095 ! axon cargo transport GO:0008088 27 14 0,000 0,04930488 0,08676452 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04930488 0,08669818 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04930488 0,08663195 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04930488 0,08656582 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04930488 0,08649979 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04930488 0,08643386 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04930488 0,08636803 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04930488 0,0863023 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04930488 0,08623667 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04930488 0,08617114 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04930488 0,08610571 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04930488 0,08604038 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04930488 0,08597515 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04930488 0,08591002 ! muscle maintenance GO:0046716 19 14 0,000 0,04930488 0,08584498 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04930488 0,08578005 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04930488 0,08571521 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04930488 0,08565047 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04930488 0,08558583 ! cell killing GO:0001906 20 14 0,000 0,04930488 0,08552128 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,04930488 0,08545684 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,04930488 0,08539249 ! cilium assembly GO:0042384 20 14 0,000 0,04930488 0,08532823 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04930488 0,08526408 ! extracellular structure organization GO:0043062 156 99 1,000 0,04960055 0,08571094 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05273365 0,0910566 ! metencephalon development GO:0022037 19 15 0,000 0,05273365 0,0909883 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05273365 0,09092009 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05273365 0,09085198 ! skin development GO:0043588 25 15 0,000 0,05273365 0,09078398 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05273365 0,09071608 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05273365 0,09064828 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05273365 0,09058058 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05273365 0,09051298 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05273365 0,09044549 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05273365 0,09037809 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05273365 0,09031079 ! adult walking behavior GO:0007628 25 15 0,000 0,05273365 0,0902436 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05273365 0,0901765 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05273365 0,09010951 ! myoblast differentiation GO:0045445 27 15 0,000 0,05273365 0,09004261 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05273365 0,08997581 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05273365 0,08990912 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05273365 0,08984252 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05273365 0,08977602 ! cerebral cortex development GO:0021987 29 15 0,000 0,05273365 0,08970961 ! response to osmotic stress GO:0006970 22 15 0,000 0,05273365 0,08964331 ! vesicle coating GO:0006901 25 15 0,000 0,05273365 0,0895771 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05273365 0,08951099 ! DNA integration GO:0015074 22 15 0,000 0,05273365 0,08944498 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05273365 0,08937907 ! peptide secretion GO:0002790 27 15 0,000 0,05273365 0,08931325 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05273365 0,08924753 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05273365 0,08918191 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05273365 0,08911638 ! neuron recognition GO:0008038 22 15 0,000 0,05273365 0,08905095 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05273365 0,08898562 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05273365 0,08892038 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05273365 0,08885524 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,05273365 0,08879019 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05273365 0,08872524 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05273365 0,08866038 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05273365 0,08859562 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05273365 0,08853095 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05273365 0,08846637 ! organic cation transport GO:0015695 19 15 0,000 0,05273365 0,08840189 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05273365 0,08833751 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05273365 0,08827321 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,05273365 0,08820902 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,05273365 0,08814491 ! defense response to virus GO:0051607 27 15 0,000 0,05273365 0,0880809 ! peptide hormone processing GO:0016486 19 15 0,000 0,05273365 0,08801698 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05273365 0,08795315 ! protein secretion GO:0009306 27 16 0,000 0,05615025 0,09358375 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,05615025 0,09351599 ! hormone secretion GO:0046879 25 16 0,000 0,05615025 0,09344832 ! bone remodeling GO:0046849 24 16 0,000 0,05615025 0,09338075 ! endothelial cell migration GO:0043542 22 16 0,000 0,05615025 0,09331328 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05615025 0,09324591 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05615025 0,09317863 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05615025 0,09311145 ! glial cell development GO:0021782 24 16 0,000 0,05615025 0,09304437 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05615025 0,09297738 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05615025 0,09291049 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05615025 0,0928437 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05615025 0,092777 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05615025 0,0927104 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,05615025 0,09264389 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05615025 0,09257748 ! fructose metabolic process GO:0006000 20 16 0,000 0,05615025 0,09251116 ! regulation of protein binding GO:0043393 27 16 0,000 0,05615025 0,09244494 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05615025 0,09237881 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05615025 0,09231278 ! protein export from nucleus GO:0006611 24 16 0,000 0,05615025 0,09224684 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05615025 0,092181 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05615025 0,09211525 ! DNA replication initiation GO:0006270 25 16 0,000 0,05615025 0,09204959 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05615025 0,09198403 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05615025 0,09191856 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05615025 0,09185319 ! diencephalon development GO:0021536 25 16 0,000 0,05615025 0,0917879 ! oogenesis GO:0048477 23 16 0,000 0,05615025 0,09172271 ! neural crest cell migration GO:0001755 24 16 0,000 0,05615025 0,09165762 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,05615025 0,09159261 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05615025 0,0915277 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05615025 0,09146288 ! steroid catabolic process GO:0006706 22 16 0,000 0,05615025 0,09139815 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05615025 0,09133351 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05615025 0,09126896 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,05615025 0,09120451 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05615025 0,09114014 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05615025 0,09107587 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05615025 0,09101168 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,05615025 0,09094759 ! nerve development GO:0021675 18 16 0,000 0,05615025 0,09088359 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05615025 0,09081968 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05615025 0,09075585 ! negative regulation of translation GO:0017148 22 16 0,000 0,05615025 0,09069212 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,05955473 0,09612342 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,05955473 0,09605601 ! negative regulation of defense response GO:0031348 19 17 0,000 0,05955473 0,0959887 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,05955473 0,09592148 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,05955473 0,09585435 ! glycerol metabolic process GO:0006071 20 17 0,000 0,05955473 0,09578732 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,05955473 0,09572038 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,05955473 0,09565354 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,05955473 0,09558679 ! signal complex assembly GO:0007172 29 17 0,000 0,05955473 0,09552013 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,05955473 0,09545357 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,05955473 0,0953871 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,05955473 0,09532072 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,05955473 0,09525443 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,05955473 0,09518823 ! memory GO:0007613 25 17 0,000 0,05955473 0,09512213 ! keratinization GO:0031424 17 17 0,000 0,05955473 0,09505612 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,05955473 0,0949902 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,05955473 0,09492437 ! retinoid metabolic process GO:0001523 22 17 0,000 0,05955473 0,09485864 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,05955473 0,09479299 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,05955473 0,09472743 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,05955473 0,09466197 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,05955473 0,0945966 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,05955473 0,09453131 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,05955473 0,09446612 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,05955473 0,09440101 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,05955473 0,094336 ! membrane budding GO:0006900 29 17 0,000 0,05955473 0,09427107 ! heme metabolic process GO:0042168 27 17 0,000 0,05955473 0,09420624 ! actin filament bundle formation GO:0051017 26 17 0,000 0,05955473 0,09414149 ! neuromuscular junction development GO:0007528 23 17 0,000 0,05955473 0,09407683 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,05955473 0,09401226 ! body fluid secretion GO:0007589 27 17 0,000 0,05955473 0,09394778 ! stem cell differentiation GO:0048863 36 17 0,000 0,05955473 0,09388339 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,05955473 0,09381909 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,05955473 0,09375487 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,05955473 0,09369075 ! sensory perception of pain GO:0019233 23 17 0,000 0,05955473 0,09362671 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,05955473 0,09356275 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,05955473 0,09349889 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,05955473 0,09343511 ! synaptogenesis GO:0007416 24 17 0,000 0,05955473 0,09337142 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,05955473 0,09330781 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,05955473 0,0932443 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,05955473 0,09318086 ! cell-cell junction organization GO:0045216 25 17 0,000 0,05955473 0,09311752 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,05955473 0,09305426 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,05955473 0,09299109 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,05955473 0,092928 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,05955473 0,092865 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,05955473 0,09280208 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,05955473 0,09273925 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,06294711 0,09795559 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,06294711 0,09788936 ! positive regulation of translation GO:0045727 28 18 0,000 0,06294711 0,09782322 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06294711 0,09775717 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,06294711 0,0976912 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06294711 0,09762533 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06294711 0,09755954 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06294711 0,09749385 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06294711 0,09742824 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06294711 0,09736272 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06294711 0,09729729 ! axis specification GO:0009798 26 18 0,000 0,06294711 0,09723194 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06294711 0,09716669 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06294711 0,09710152 ! pancreas development GO:0031016 26 18 0,000 0,06294711 0,09703644 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,06294711 0,09697144 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06294711 0,09690653 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06294711 0,09684171 ! response to retinoic acid GO:0032526 25 18 0,000 0,06294711 0,09677698 ! pigmentation during development GO:0048066 31 18 0,000 0,06294711 0,09671233 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06294711 0,09664777 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,06294711 0,0965833 ! fucose metabolic process GO:0006004 26 18 0,000 0,06294711 0,09651891 ! response to fungus GO:0009620 19 18 0,000 0,06294711 0,0964546 ! peptide cross-linking GO:0018149 31 18 0,000 0,06294711 0,09639039 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06294711 0,09632626 ! heart process GO:0003015 27 18 0,000 0,06294711 0,09626221 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06294711 0,09619825 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06294711 0,09613437 ! visual learning GO:0008542 35 18 0,000 0,06294711 0,09607058 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06294711 0,09600687 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06294711 0,09594325 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06294711 0,09587971 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,06294711 0,09581626 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06294711 0,09575288 ! vitamin transport GO:0051180 24 18 0,000 0,06294711 0,0956896 ! hormone transport GO:0009914 27 18 0,000 0,06294711 0,09562639 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,06294711 0,09556328 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06294711 0,09550024 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06294711 0,09543729 ! cell-cell recognition GO:0009988 20 18 0,000 0,06294711 0,09537441 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06294711 0,09531163 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06294711 0,09524892 ! regulation of glucose import GO:0046324 21 18 0,000 0,06294711 0,0951863 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,06294711 0,09512376 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06294711 0,0950613 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,06294711 0,09499893 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,06294711 0,09493663 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06632746 0,0999693 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,06632746 0,09990383 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,06632746 0,09983845 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06632746 0,09977315 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06632746 0,09970794 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,06632746 0,09964282 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06632746 0,09957778 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,06632746 0,09951282 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,06632746 0,09944795 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06632746 0,09938316 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06632746 0,09931846 ! regeneration GO:0031099 32 19 0,000 0,06632746 0,09925384 ! response to alkaloid GO:0043279 32 19 0,000 0,06632746 0,09918931 ! sensory perception of taste GO:0050909 23 19 0,000 0,06632746 0,09912486 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,06632746 0,09906049 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06632746 0,09899621 ! peroxisome organization GO:0007031 29 19 0,000 0,06632746 0,09893201 ! digestive system process GO:0022600 30 19 0,000 0,06632746 0,09886789 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06632746 0,09880386 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06632746 0,09873991 ! response to vitamin A GO:0033189 26 19 0,000 0,06632746 0,09867604 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06632746 0,09861225 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06632746 0,09854855 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,06632746 0,09848493 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,06632746 0,09842139 ! response to starvation GO:0042594 30 19 0,000 0,06632746 0,09835793 ! sex determination GO:0007530 29 19 0,000 0,06632746 0,09829456 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,06632746 0,09823126 ! plasma membrane fusion GO:0045026 23 19 0,000 0,06632746 0,09816805 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,06632746 0,09810492 ! cytolysis GO:0019835 20 19 0,000 0,06632746 0,09804187 ! renal system process GO:0003014 35 19 0,000 0,06632746 0,0979789 ! vasodilation GO:0042311 33 19 0,000 0,06632746 0,09791602 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06632746 0,09785321 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06632746 0,09779048 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,06632746 0,09772784 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,06632746 0,09766527 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,06632746 0,09760279 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06632746 0,09754038 ! sarcomere organization GO:0045214 23 19 0,000 0,06632746 0,09747805 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06632746 0,09741581 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06632746 0,09735364 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06632746 0,09729155 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,06632746 0,09722954 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,06632746 0,09716761 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,06632746 0,09710576 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,06632746 0,09704399 ! protein stabilization GO:0050821 26 19 0,000 0,06632746 0,0969823 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0696958 0,10184266 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0696958 0,10177799 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0696958 0,10171341 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0696958 0,10164892 ! response to vitamin GO:0033273 29 20 0,000 0,0696958 0,1015845 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0696958 0,10152017 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0696958 0,10145591 ! spinal cord development GO:0021510 31 20 0,000 0,0696958 0,10139174 ! response to ethanol GO:0045471 37 20 0,000 0,0696958 0,10132765 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0696958 0,10126364 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,0696958 0,10119971 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0696958 0,10113586 ! chromosome condensation GO:0030261 31 20 0,000 0,0696958 0,10107209 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0696958 0,10100841 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,0696958 0,1009448 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,0696958 0,10088127 ! DNA modification GO:0006304 28 20 0,000 0,0696958 0,10081783 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,0696958 0,10075446 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,0696958 0,10069117 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,0696958 0,10062796 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0696958 0,10056483 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0696958 0,10050178 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,0696958 0,10043881 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0696958 0,10037592 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0696958 0,10031311 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0696958 0,10025037 ! alditol metabolic process GO:0019400 24 20 0,000 0,0696958 0,10018771 ! actin filament-based movement GO:0030048 34 20 0,000 0,0696958 0,10012514 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,07305218 0,10488141 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07305218 0,10481598 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07305218 0,10475064 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,07305218 0,10468537 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07305218 0,10462019 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07305218 0,10455509 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07305218 0,10449006 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07305218 0,10442512 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07305218 0,10436026 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07305218 0,10429548 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07305218 0,10423078 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,07305218 0,10416616 ! vesicle docking GO:0048278 27 21 0,000 0,07305218 0,10410163 ! phototransduction GO:0007602 25 21 0,000 0,07305218 0,10403717 ! dendrite development GO:0016358 35 21 0,000 0,07305218 0,10397279 ! visual behavior GO:0007632 39 21 0,000 0,07305218 0,10390849 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07305218 0,10384427 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,07305218 0,10378013 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07305218 0,10371606 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07305218 0,10365208 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07305218 0,10358818 ! cell aging GO:0007569 32 21 0,000 0,07305218 0,10352435 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,07305218 0,10346061 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,07305218 0,10339694 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07305218 0,10333335 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07305218 0,10326984 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07305218 0,1032064 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07305218 0,10314305 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07305218 0,10307977 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07305218 0,10301657 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07305218 0,10295345 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07305218 0,1028904 ! fatty acid transport GO:0015908 30 21 0,000 0,07305218 0,10282743 ! immunoglobulin production GO:0002377 33 21 0,000 0,07305218 0,10276454 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07305218 0,10270173 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,07305218 0,10263899 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07305218 0,10257633 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07305218 0,10251374 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,07305218 0,10245123 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07305218 0,1023888 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07305218 0,10232645 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07305218 0,10226417 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07305218 0,10220196 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07305218 0,10213983 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07305218 0,10207778 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07305218 0,1020158 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07305218 0,1019539 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07305218 0,10189207 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07305218 0,10183032 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,07639665 0,1064278 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,07639665 0,10636337 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,07639665 0,10629903 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,07639665 0,10623476 ! viral genome replication GO:0019079 29 22 0,000 0,07639665 0,10617057 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07639665 0,10610646 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07639665 0,10604242 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07639665 0,10597846 ! molting cycle process GO:0022404 40 22 0,000 0,07639665 0,10591458 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,07639665 0,10585078 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07639665 0,10578705 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07639665 0,1057234 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,07639665 0,10565983 ! vasculogenesis GO:0001570 33 22 0,000 0,07639665 0,10559633 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,07639665 0,10553291 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,07639665 0,10546956 ! lysosome organization GO:0007040 37 22 0,000 0,07639665 0,1054063 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07639665 0,1053431 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,07639665 0,10527998 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,07639665 0,10521694 ! regulation of behavior GO:0050795 38 22 0,000 0,07639665 0,10515398 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07639665 0,10509109 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,07639665 0,10502827 ! membrane depolarization GO:0051899 35 22 0,000 0,07639665 0,10496553 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,07639665 0,10490286 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07639665 0,10484027 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,07639665 0,10477775 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07639665 0,10471531 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07639665 0,10465294 ! blastocyst development GO:0001824 37 22 0,000 0,07639665 0,10459065 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,07639665 0,10452843 ! protein tetramerization GO:0051262 39 22 0,000 0,07639665 0,10446629 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,07972924 0,10895856 ! neuron fate commitment GO:0048663 32 23 0,000 0,07972924 0,10889385 ! embryonic pattern specification GO:0009880 31 23 0,000 0,07972924 0,10882923 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,07972924 0,10876468 ! myelination GO:0042552 35 23 0,000 0,07972924 0,10870021 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,07972924 0,10863581 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,07972924 0,10857149 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,07972924 0,10850725 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,07972924 0,10844308 ! vesicle targeting GO:0006903 32 23 0,000 0,07972924 0,10837899 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,07972924 0,10831497 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,07972924 0,10825103 ! osteoblast differentiation GO:0001649 40 23 0,000 0,07972924 0,10818717 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,07972924 0,10812338 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,07972924 0,10805966 ! interaction with host GO:0051701 37 23 0,000 0,07972924 0,10799602 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,07972924 0,10793246 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,07972924 0,10786897 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,07972924 0,10780556 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,07972924 0,10774221 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,07972924 0,10767895 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,07972924 0,10761576 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,07972924 0,10755264 ! cell fate determination GO:0001709 45 23 0,000 0,07972924 0,1074896 ! pentose metabolic process GO:0019321 31 23 0,000 0,07972924 0,10742663 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,07972924 0,10736373 ! spermatid development GO:0007286 33 23 0,000 0,07972924 0,10730091 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,07972924 0,10723816 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,07972924 0,10717548 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,07972924 0,10711288 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,07972924 0,10705035 ! telomere organization GO:0032200 32 23 0,000 0,07972924 0,10698789 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,07972924 0,10692551 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,07972924 0,1068632 ! regulation of amine transport GO:0051952 38 23 0,000 0,07972924 0,10680096 ! liver development GO:0001889 40 23 0,000 0,07972924 0,10673879 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,08304999 0,11111983 ! initiation of viral infection GO:0019059 42 24 0,000 0,08304999 0,11105522 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08304999 0,11099069 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,08304999 0,11092624 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08304999 0,11086186 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08304999 0,11079756 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,08304999 0,11073333 ! fat cell differentiation GO:0045444 37 24 0,000 0,08304999 0,11066917 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08304999 0,11060509 ! sperm motility GO:0030317 27 24 0,000 0,08304999 0,11054108 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,08304999 0,11047715 ! vacuole organization GO:0007033 39 24 0,000 0,08304999 0,11041329 ! receptor metabolic process GO:0043112 37 24 0,000 0,08304999 0,1103495 ! neural crest cell development GO:0014032 39 24 0,000 0,08304999 0,11028579 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,08304999 0,11022215 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08304999 0,11015858 ! base-excision repair GO:0006284 31 24 0,000 0,08304999 0,11009509 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08304999 0,11003167 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,08304999 0,10996833 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,08304999 0,10990506 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08304999 0,10984185 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08304999 0,10977873 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,08635896 0,11408707 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,08635896 0,11402158 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,08635896 0,11395617 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,08635896 0,11389082 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,08635896 0,11382556 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,08635896 0,11376037 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,08635896 0,11369525 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 43 25 0,000 0,08635896 0,1136302 ! male gonad development GO:0008584 33 25 0,000 0,08635896 0,11356524 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,08635896 0,11350034 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,08635896 0,11343552 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,08635896 0,11337077 ! phospholipid transport GO:0015914 35 25 0,000 0,08635896 0,1133061 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,08635896 0,1132415 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,08635896 0,11317698 ! detection of light stimulus GO:0009583 30 25 0,000 0,08635896 0,11311253 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,08635896 0,11304815 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,08635896 0,11298384 ! leukocyte proliferation GO:0070661 39 25 0,000 0,08635896 0,11291961 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,08635896 0,11285545 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,08965616 0,11709777 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,08965616 0,11703132 ! translational initiation GO:0006413 43 26 0,000 0,08965616 0,11696493 ! regulation of pH GO:0006885 36 26 0,000 0,08965616 0,11689863 ! circadian rhythm GO:0007623 42 26 0,000 0,08965616 0,1168324 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,08965616 0,11676624 ! post-embryonic development GO:0009791 42 26 0,000 0,08965616 0,11670016 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,08965616 0,11663415 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,08965616 0,11656822 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,08965616 0,11650236 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,08965616 0,11643658 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,08965616 0,11637087 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,08965616 0,11630523 ! regulation of coagulation GO:0050818 39 26 0,000 0,08965616 0,11623967 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09294166 0,12043145 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09294166 0,12036364 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09294166 0,12029591 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09294166 0,12022825 ! membrane docking GO:0022406 39 27 0,000 0,09294166 0,12016067 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09294166 0,12009316 ! catechol metabolic process GO:0009712 43 27 0,000 0,09294166 0,12002573 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09294166 0,11995838 ! acute-phase response GO:0006953 42 27 0,000 0,09294166 0,1198911 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09294166 0,11982389 ! myofibril assembly GO:0030239 36 27 0,000 0,09294166 0,11975677 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09294166 0,11968971 ! response to ionizing radiation GO:0010212 47 27 0,000 0,09294166 0,11962273 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09294166 0,11955583 ! natural killer cell activation GO:0030101 35 27 0,000 0,09294166 0,119489 ! lipid oxidation GO:0034440 38 27 0,000 0,09294166 0,11942225 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09294166 0,11935557 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,09294166 0,11928897 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09294166 0,11922243 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,09294166 0,11915598 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09294166 0,1190896 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,09294166 0,11902329 ! gene silencing GO:0016458 41 27 0,000 0,09294166 0,11895705 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,09621549 0,12307877 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,09621549 0,12301036 ! phenol metabolic process GO:0018958 44 28 0,000 0,09621549 0,12294202 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,09621549 0,12287375 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,09621549 0,12280557 ! cell junction assembly GO:0034329 56 28 0,000 0,09621549 0,12273745 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,09621549 0,12266942 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,09621549 0,12260146 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,09621549 0,12253357 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,09621549 0,12246576 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,09621549 0,12239803 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,09621549 0,12233037 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,09621549 0,12226278 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,09621549 0,12219527 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,09621549 0,12212783 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,09621549 0,12206047 ! mesoderm formation GO:0001707 46 28 0,000 0,09621549 0,12199318 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,09621549 0,12192597 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,09621549 0,12185883 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,09621549 0,12179176 ! ensheathment of neurons GO:0007272 43 28 0,000 0,09621549 0,12172477 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,09621549 0,12165785 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,09621549 0,12159101 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,09621549 0,12152423 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,09621549 0,12145754 ! placenta development GO:0001890 37 28 0,000 0,09621549 0,12139091 ! regulation of B cell activation GO:0050864 42 28 0,000 0,09621549 0,12132436 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,09947769 0,12536914 ! regulation of innate immune response GO:0045088 38 29 0,000 0,09947769 0,12530049 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,09947769 0,1252319 ! protein targeting to membrane GO:0006612 53 29 0,000 0,09947769 0,1251634 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,09947769 0,12509496 ! mismatch repair GO:0006298 34 29 0,000 0,09947769 0,12502661 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,09947769 0,12495832 ! muscle cell development GO:0055001 38 29 0,000 0,09947769 0,12489011 ! formation of primary germ layer GO:0001704 48 29 0,000 0,09947769 0,12482198 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,09947769 0,12475392 ! eye morphogenesis GO:0048592 51 29 0,000 0,09947769 0,12468593 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,09947769 0,12461802 ! tissue homeostasis GO:0001894 42 29 0,000 0,09947769 0,12455018 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,1027283 0,12855011 ! organic anion transport GO:0015711 51 30 0,000 0,1027283 0,1284802 ! cholesterol transport GO:0030301 46 30 0,000 0,1027283 0,12841038 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,1027283 0,12834063 ! spliceosome assembly GO:0000245 49 30 0,000 0,1027283 0,12827095 ! spindle organization GO:0007051 37 30 0,000 0,1027283 0,12820135 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,1027283 0,12813183 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,1027283 0,12806238 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,1027283 0,12799301 ! ceramide metabolic process GO:0006672 43 30 0,000 0,1027283 0,12792371 ! hindbrain development GO:0030902 45 30 0,000 0,1027283 0,12785449 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,1027283 0,12778534 ! adult locomotory behavior GO:0008344 47 30 0,000 0,1027283 0,12771627 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,1027283 0,12764727 ! response to heat GO:0009408 41 30 0,000 0,1027283 0,12757834 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,1027283 0,12750949 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,1027283 0,12744072 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,10596736 0,13138811 ! negative regulation of secretion GO:0051048 49 31 0,000 0,10596736 0,13131732 ! mammary gland development GO:0030879 57 31 0,000 0,10596736 0,1312466 ! glial cell differentiation GO:0010001 55 31 0,000 0,10596736 0,13117596 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,10596736 0,1311054 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,10596736 0,13103491 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,10596736 0,1309645 ! odontogenesis GO:0042476 50 31 0,000 0,10596736 0,13089417 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,10596736 0,13082391 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,10596736 0,13075372 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,10596736 0,13068361 ! metanephros development GO:0001656 58 31 0,000 0,10596736 0,13061358 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,10596736 0,13054362 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,10596736 0,13047373 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,10596736 0,13040393 ! RNA modification GO:0009451 40 31 0,000 0,10596736 0,13033419 ! regulation of muscle development GO:0048634 48 32 0,000 0,10919492 0,13423213 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,10919492 0,13416042 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,10919492 0,13408879 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,10919492 0,13401724 ! meiosis I GO:0007127 52 32 0,000 0,10919492 0,13394577 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,10919492 0,13387437 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,10919492 0,13380304 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,10919492 0,1337318 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,10919492 0,13366062 ! peripheral nervous system development GO:0007422 53 32 0,000 0,10919492 0,13358953 ! regulation of protein stability GO:0031647 48 32 0,000 0,10919492 0,13351851 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,10919492 0,13344756 ! cytokine production GO:0001816 44 32 0,000 0,10919492 0,13337669 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,10919492 0,1333059 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,10919492 0,13323518 ! vesicle localization GO:0051648 47 32 0,000 0,10919492 0,13316453 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,11241101 0,13701394 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,11241101 0,13694137 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11241101 0,13686888 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11241101 0,13679646 ! sister chromatid segregation GO:0000819 46 33 0,000 0,11241101 0,13672412 ! ear morphogenesis GO:0042471 42 33 0,000 0,11241101 0,13665186 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11241101 0,13657967 ! cell junction organization GO:0034330 63 33 0,000 0,11241101 0,13650756 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,11241101 0,13643552 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11241101 0,13636356 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,11241101 0,13629168 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,11241101 0,13621987 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,11241101 0,13614814 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11241101 0,13607648 ! lipid homeostasis GO:0055088 55 33 0,000 0,11241101 0,1360049 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11241101 0,13593339 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11241101 0,13586196 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,11241101 0,13579061 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11241101 0,13571932 ! cytokinesis GO:0000910 52 33 0,000 0,11241101 0,13564812 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,11241101 0,13557699 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,11561567 0,13936899 ! mRNA catabolic process GO:0006402 48 34 0,000 0,11561567 0,13929598 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,11561567 0,13922305 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,11561567 0,1391502 ! feeding behavior GO:0007631 45 34 0,000 0,11561567 0,13907742 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,11561567 0,13900472 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,11561567 0,1389321 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,11561567 0,13885955 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,11561567 0,13878707 ! neuron migration GO:0001764 46 34 0,000 0,11561567 0,13871467 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,11561567 0,13864235 ! female gamete generation GO:0007292 43 34 0,000 0,11561567 0,1385701 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,11561567 0,13849793 ! polyol metabolic process GO:0019751 44 34 0,000 0,11561567 0,13842584 ! aerobic respiration GO:0009060 47 34 0,000 0,11561567 0,13835381 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,11561567 0,13828187 ! embryonic organ development GO:0048568 45 34 0,000 0,11561567 0,13820999 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,11561567 0,1381382 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,11880894 0,14187983 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,11880894 0,1418062 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,11880894 0,14173265 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,11880894 0,14165918 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,11880894 0,14158578 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,11880894 0,14151246 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,11880894 0,14143921 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,11880894 0,14136604 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,11880894 0,14129295 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,11880894 0,14121993 ! glycogen metabolic process GO:0005977 48 35 0,000 0,11880894 0,14114698 ! pigment metabolic process GO:0042440 61 35 0,000 0,11880894 0,14107411 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,11880894 0,14100132 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,11880894 0,1409286 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,12199086 0,14462834 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,12199086 0,14455383 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,12199086 0,14447939 ! negative regulation of binding GO:0051100 58 36 0,000 0,12199086 0,14440503 ! organic ether metabolic process GO:0018904 46 36 0,000 0,12199086 0,14433075 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,12199086 0,14425655 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,12199086 0,14418242 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,12199086 0,14410836 ! glucan metabolic process GO:0044042 49 36 0,000 0,12199086 0,14403439 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,12516148 0,1477021 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,12516148 0,14762636 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,12516148 0,14755069 ! learning GO:0007612 67 37 0,000 0,12516148 0,1474751 ! ion transmembrane transport GO:0034220 56 37 0,000 0,12516148 0,14739959 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,12516148 0,14732416 ! regulation of protein secretion GO:0050708 51 37 0,000 0,12516148 0,1472488 ! amino acid activation GO:0043038 52 37 0,000 0,12516148 0,14717352 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,12516148 0,14709831 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,12832083 0,15073437 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,12832083 0,15065743 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,12832083 0,15058056 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,12832083 0,15050377 ! phagocytosis GO:0006909 60 38 0,000 0,12832083 0,15042706 ! mesenchymal cell development GO:0014031 64 38 0,000 0,12832083 0,15035043 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,12832083 0,15027388 ! maintenance of location in cell GO:0051651 69 38 0,000 0,12832083 0,15019741 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,13146895 0,15380395 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,13146895 0,15372576 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,13146895 0,15364765 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,13146895 0,15356962 ! male sex differentiation GO:0046661 53 39 0,000 0,13146895 0,15349166 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,13146895 0,15341379 ! chromatin remodeling GO:0006338 68 39 0,000 0,13146895 0,15333599 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,13146895 0,15325827 ! JNK cascade GO:0007254 54 39 0,000 0,13146895 0,15318064 ! developmental growth GO:0048589 62 39 0,000 0,13146895 0,15310308 ! synapse organization GO:0050808 55 39 0,000 0,13146895 0,15302559 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,13460587 0,15659763 ! response to calcium ion GO:0051592 58 40 0,000 0,13460587 0,15651846 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,13460587 0,15643937 ! regulation of tube size GO:0035150 60 40 0,000 0,13460587 0,15636036 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,13460587 0,15628143 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,13460587 0,15620258 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,13460587 0,15612381 ! peptide metabolic process GO:0006518 56 40 0,000 0,13460587 0,15604512 ! inner ear development GO:0048839 57 40 0,000 0,13460587 0,1559665 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,13460587 0,15588797 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,13460587 0,15580952 ! B cell differentiation GO:0030183 62 40 0,000 0,13460587 0,15573114 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,13460587 0,15565285 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,13460587 0,15557463 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,13460587 0,15549649 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,13773165 0,15902751 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,13773165 0,15894772 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,13773165 0,15886801 ! glucose transport GO:0015758 52 41 0,000 0,13773165 0,15878837 ! endosome transport GO:0016197 71 41 0,000 0,13773165 0,15870882 ! striated muscle contraction GO:0006941 62 41 0,000 0,13773165 0,15862935 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,13773165 0,15854995 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,13773165 0,15847064 ! biopolymer methylation GO:0043414 62 41 0,000 0,13773165 0,1583914 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,13773165 0,15831225 ! mitochondrial transport GO:0006839 60 42 0,000 0,14084632 0,16181146 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,14084632 0,16173067 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,14084632 0,16164997 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,14084632 0,16156934 ! cellular component disassembly GO:0022411 64 42 0,000 0,14084632 0,1614888 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,14084632 0,16140834 ! hexose transport GO:0008645 54 42 0,000 0,14084632 0,16132796 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,14084632 0,16124765 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,14084632 0,16116743 ! excretion GO:0007588 63 42 0,000 0,14084632 0,16108729 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,14084632 0,16100722 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,14084632 0,16092724 ! regulation of cell shape GO:0008360 78 42 0,000 0,14084632 0,16084734 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,14394991 0,16431008 ! neuromuscular process GO:0050905 79 43 0,000 0,14394991 0,16422857 ! activation of caspase activity GO:0006919 65 43 0,000 0,14394991 0,16414715 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,14394991 0,16406581 ! tRNA processing GO:0008033 49 43 0,000 0,14394991 0,16398455 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,14394991 0,16390337 ! vesicle organization GO:0016050 79 43 0,000 0,14394991 0,16382227 ! methylation GO:0032259 64 43 0,000 0,14394991 0,16374125 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,14704247 0,16717632 ! glycolysis GO:0006096 53 44 0,000 0,14704247 0,16709372 ! regulation of action potential GO:0001508 71 44 0,000 0,14704247 0,16701121 ! regulation of ion transport GO:0043269 57 44 0,000 0,14704247 0,16692877 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,14704247 0,16684642 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,14704247 0,16676415 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,14704247 0,16668196 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,14704247 0,16659985 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,14704247 0,16651782 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,14704247 0,16643587 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,14704247 0,166354 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,14704247 0,16627222 ! RNA catabolic process GO:0006401 64 45 0,000 0,15012404 0,16967336 ! positive regulation of defense response GO:0031349 59 45 0,000 0,15012404 0,16959002 ! regulation of translational initiation GO:0006446 64 45 0,000 0,15012404 0,16950677 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,15012404 0,1694236 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,15012404 0,16934051 ! cell recognition GO:0008037 58 45 0,000 0,15012404 0,1692575 ! cell maturation GO:0048469 60 45 0,000 0,15012404 0,16917457 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,15319465 0,17255029 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,15319465 0,17246583 ! cell redox homeostasis GO:0045454 63 46 0,000 0,15319465 0,17238145 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,15319465 0,17229716 ! regulation of ossification GO:0030278 71 46 0,000 0,15319465 0,17221295 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,15319465 0,17212882 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,15625434 0,17548094 ! viral infectious cycle GO:0019058 71 47 0,000 0,15625434 0,1753953 ! endocrine system development GO:0035270 83 47 0,000 0,15625434 0,17530974 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,15625434 0,17522427 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,15625434 0,17513888 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,15625434 0,17505357 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,15625434 0,17496834 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,15625434 0,1748832 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,15625434 0,17479814 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,15625434 0,17471316 ! chloride transport GO:0006821 67 48 0,000 0,15930314 0,17803558 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,15930314 0,17794912 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,15930314 0,17786273 ! response to temperature stimulus GO:0009266 62 48 0,000 0,15930314 0,17777643 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,15930314 0,17769022 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,15930314 0,17760409 ! gastrulation GO:0007369 73 48 0,000 0,15930314 0,17751804 ! heart morphogenesis GO:0003007 65 48 0,000 0,15930314 0,17743207 ! regulation of DNA replication GO:0006275 75 48 0,000 0,15930314 0,17734619 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,15930314 0,17726039 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,15930314 0,17717468 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,15930314 0,17708904 ! regulation of endocytosis GO:0030100 63 48 0,000 0,15930314 0,17700349 ! nuclear export GO:0051168 69 48 0,000 0,15930314 0,17691803 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,15930314 0,17683264 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,15930314 0,17674734 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,16234111 0,18003113 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,16234111 0,17994436 ! sensory perception of smell GO:0007608 61 49 0,000 0,16234111 0,17985768 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,16234111 0,17977109 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,16234111 0,17968458 ! RNA elongation GO:0006354 62 49 0,000 0,16234111 0,17959815 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,16234111 0,1795118 ! germ cell development GO:0007281 68 49 0,000 0,16234111 0,17942554 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,16234111 0,17933936 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,16234111 0,17925327 ! maintenance of location GO:0051235 84 49 0,000 0,16234111 0,17916725 ! regulation of actin filament length GO:0030832 72 50 0,000 0,16536827 0,18242064 ! ear development GO:0043583 72 50 0,000 0,16536827 0,18233319 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,16536827 0,18224582 ! membrane fusion GO:0006944 80 50 0,000 0,16536827 0,18215854 ! positive regulation of growth GO:0045927 67 50 0,000 0,16536827 0,18207134 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,16536827 0,18198422 ! proton transport GO:0015992 75 50 0,000 0,16536827 0,18189719 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,16536827 0,18181024 ! positive regulation of secretion GO:0051047 71 51 0,000 0,16838467 0,1850381 ! hydrogen transport GO:0006818 77 51 0,000 0,16838467 0,18494973 ! muscle fiber development GO:0048747 74 51 0,000 0,16838467 0,18486145 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,16838467 0,18477325 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,16838467 0,18468514 ! adult behavior GO:0030534 80 51 0,000 0,16838467 0,18459711 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,16838467 0,18450916 ! regulation of cellular component size GO:0032535 74 52 0,000 0,17139033 0,18771322 ! aging GO:0007568 79 52 0,000 0,17139033 0,18762388 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,17139033 0,18753462 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,17139033 0,18744544 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,17438531 0,19063033 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,17438531 0,19053977 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,17438531 0,19044929 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,17438531 0,1903589 ! kidney development GO:0001822 90 53 0,000 0,17438531 0,1902686 ! single fertilization GO:0007338 59 53 0,000 0,17438531 0,19017838 ! amino acid transport GO:0006865 84 54 0,000 0,17736963 0,1933413 ! regulation of mitosis GO:0007088 84 54 0,000 0,17736963 0,19324971 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,17736963 0,19315821 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,17736963 0,1930668 ! DNA catabolic process GO:0006308 67 54 0,000 0,17736963 0,19297547 ! detection of external stimulus GO:0009581 66 54 0,000 0,17736963 0,19288423 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,17736963 0,19279307 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,17736963 0,19270201 ! exocytosis GO:0006887 74 55 0,000 0,18034333 0,19584026 ! mesoderm development GO:0007498 76 55 0,000 0,18034333 0,19574784 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,18034333 0,1956555 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,18034333 0,19556326 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,18330646 0,19868278 ! carbohydrate transport GO:0008643 74 57 0,000 0,18625904 0,20178794 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,18625904 0,20169293 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,18625904 0,20159802 ! camera-type eye development GO:0043010 88 57 0,000 0,18625904 0,20150319 ! secondary metabolic process GO:0019748 84 57 0,000 0,18625904 0,20140846 ! viral reproductive process GO:0022415 87 58 0,000 0,18920112 0,20449369 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,18920112 0,20439764 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,18920112 0,20430167 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,19213272 0,2073699 ! activation of MAPK activity GO:0000187 84 59 0,000 0,19213272 0,20727264 ! actin filament organization GO:0007015 95 59 0,000 0,19213272 0,20717546 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,19213272 0,20707838 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,1950539 0,21012832 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,1950539 0,21002995 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,1950539 0,20993166 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,1950539 0,20983347 ! fertilization GO:0009566 68 60 0,000 0,1950539 0,20973537 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,1950539 0,20963737 ! meiosis GO:0007126 96 61 0,000 0,19796468 0,2126664 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,19796468 0,21256711 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,19796468 0,21246792 ! urogenital system development GO:0001655 101 61 0,000 0,19796468 0,21236882 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,19796468 0,21226982 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,19796468 0,2121709 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,19796468 0,21207208 ! amine catabolic process GO:0009310 90 62 0,000 0,2008651 0,21507902 ! neurotransmitter transport GO:0006836 81 62 0,000 0,2008651 0,21497893 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,2008651 0,21487894 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,2008651 0,21477905 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,2008651 0,21467924 ! meiotic cell cycle GO:0051321 97 62 0,000 0,2008651 0,21457953 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,2037552 0,2175659 ! viral reproduction GO:0016032 92 63 0,000 0,2037552 0,21746494 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,20663501 0,22043623 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,20663501 0,22033404 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,20663501 0,22023194 ! hexose catabolic process GO:0019320 82 64 0,000 0,20663501 0,22012993 ! adaptive immune response GO:0002250 94 64 0,000 0,20663501 0,22002802 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 0,000 0,20950457 0,22298033 ! B cell activation GO:0042113 104 65 0,000 0,20950457 0,2228772 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,20950457 0,22277416 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,20950457 0,22267121 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,20950457 0,22256836 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,20950457 0,22246561 ! activation of immune response GO:0002253 83 65 0,000 0,20950457 0,22236295 ! protein oligomerization GO:0051259 100 65 0,000 0,20950457 0,22226038 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,21236391 0,22518995 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,21236391 0,22508617 ! antigen processing and presentation GO:0019882 96 66 0,000 0,21236391 0,2249825 ! axon guidance GO:0007411 99 66 0,000 0,21236391 0,22487891 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,21236391 0,22477542 ! regulation of immune effector process GO:0002697 101 66 0,000 0,21236391 0,22467203 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,21521308 0,22758165 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,21521308 0,22747706 ! acute inflammatory response GO:0002526 92 68 0,000 0,2180521 0,23037199 ! learning or memory GO:0007611 123 68 0,000 0,2180521 0,23026622 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,2180521 0,23016055 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,2180521 0,23005497 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,2180521 0,22994949 ! inorganic anion transport GO:0015698 93 68 0,000 0,2180521 0,2298441 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,22088101 0,23271935 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,22088101 0,23261279 ! response to drug GO:0042493 108 69 0,000 0,22088101 0,23250633 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,22088101 0,23239997 ! response to metal ion GO:0010038 103 70 0,000 0,22369986 0,23525819 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,22369986 0,23515067 ! eye development GO:0001654 111 70 0,000 0,22369986 0,23504325 ! amine transport GO:0015837 101 70 0,000 0,22369986 0,23493592 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,22369986 0,23482869 ! regulation of catabolic process GO:0009894 106 70 0,000 0,22369986 0,23472157 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,22650866 0,23756038 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,22650866 0,23745211 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,22650866 0,23734393 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,22650866 0,23723585 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,22650866 0,23712787 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,22650866 0,23701998 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,22930746 0,23983955 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,22930746 0,23973053 ! negative regulation of transport GO:0051051 116 73 0,000 0,2320963 0,24253589 ! regulation of blood pressure GO:0008217 107 73 0,000 0,2320963 0,24242574 ! mitochondrion organization GO:0007005 104 73 0,000 0,2320963 0,2423157 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,2320963 0,24220576 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,2348752 0,24499454 ! digestion GO:0007586 97 74 0,000 0,2348752 0,24488349 ! protein import into nucleus GO:0006606 118 74 0,000 0,2348752 0,24477253 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,2348752 0,24466167 ! blood coagulation GO:0007596 116 75 0,000 0,23764421 0,24743399 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,23764421 0,24732203 ! response to nutrient GO:0007584 104 75 0,000 0,23764421 0,24721017 ! regulation of ligase activity GO:0051340 114 75 0,000 0,23764421 0,24709841 ! nuclear import GO:0051170 121 75 0,000 0,23764421 0,24698675 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,23764421 0,2468752 ! amine biosynthetic process GO:0009309 97 76 0,000 0,24040335 0,24962876 ! tRNA metabolic process GO:0006399 95 76 0,000 0,24040335 0,24951612 ! response to unfolded protein GO:0006986 99 76 0,000 0,24040335 0,24940357 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,24040335 0,24929112 ! regulation of protein transport GO:0051223 114 76 0,000 0,24040335 0,24917878 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,24315267 0,25191493 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,24315267 0,2518015 ! gland development GO:0048732 148 77 0,000 0,24315267 0,25168818 ! protein ubiquitination GO:0016567 125 77 0,000 0,24315267 0,25157496 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,24315267 0,25146184 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,24315267 0,25134883 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,24315267 0,25123591 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,24589219 0,25395242 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,24589219 0,25383844 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,24862195 0,25654127 ! cellular respiration GO:0045333 107 79 0,000 0,24862195 0,25642623 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,24862195 0,25631129 ! T cell activation GO:0042110 134 79 0,000 0,24862195 0,25619646 ! regulation of lyase activity GO:0051339 133 79 0,000 0,24862195 0,25608173 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,24862195 0,2559671 ! chromatin assembly GO:0031497 102 80 0,000 0,25134199 0,25865171 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,25134199 0,25853604 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,25134199 0,25842047 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,25134199 0,258305 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,25134199 0,25818963 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,25405234 0,26085731 ! hemostasis GO:0007599 125 81 0,000 0,25405234 0,26074091 ! mRNA transport GO:0051028 121 81 0,000 0,25405234 0,26062461 ! response to protein stimulus GO:0051789 111 81 0,000 0,25405234 0,26050842 ! regulation of neurological system process GO:0031644 122 81 0,000 0,25405234 0,26039233 ! vitamin metabolic process GO:0006766 103 81 0,000 0,25405234 0,26027634 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,25405234 0,26016045 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,25675303 0,26280906 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,2594441 0,26544547 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,2594441 0,26532744 ! regulation of defense response GO:0031347 117 84 0,000 0,26212557 0,26795059 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,26212557 0,26783155 ! sterol metabolic process GO:0016125 120 84 0,000 0,26212557 0,26771262 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,26479749 0,27032145 ! rRNA metabolic process GO:0016072 107 85 0,000 0,26479749 0,27020152 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,26479749 0,2700817 ! regulation of protein localization GO:0032880 132 85 0,000 0,26479749 0,26996198 ! regulation of membrane potential GO:0042391 128 85 0,000 0,26479749 0,26984237 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,26479749 0,26972287 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,26745989 0,27231419 ! nucleosome organization GO:0034728 114 87 0,000 0,2701128 0,27489356 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,2701128 0,27477198 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,2701128 0,27465051 ! female pregnancy GO:0007565 130 87 0,000 0,2701128 0,27452914 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,2701128 0,27440788 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,27275626 0,27697103 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,27275626 0,27684881 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,27275626 0,27672668 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,27275626 0,27660467 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,27539029 0,27915278 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,27539029 0,27902981 ! regulation of T cell activation GO:0050863 128 89 0,000 0,27539029 0,27890694 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,27801493 0,28144117 ! hormone metabolic process GO:0042445 121 90 0,000 0,27801493 0,28131735 ! RNA localization GO:0006403 135 91 0,000 0,28063022 0,28383883 ! ATP metabolic process GO:0046034 137 91 0,000 0,28063022 0,28371407 ! response to virus GO:0009615 122 91 0,000 0,28063022 0,28358941 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,28323618 0,28609715 ! positive regulation of immune response GO:0050778 121 92 0,000 0,28323618 0,28597156 ! sulfur metabolic process GO:0006790 118 92 0,000 0,28323618 0,28584608 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,28583285 0,28834016 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,28583285 0,28821375 ! electron transport chain GO:0022900 123 94 0,000 0,28842027 0,29069527 ! carboxylic acid transport GO:0046942 147 95 0,000 0,29099845 0,29316533 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,29356745 0,29562396 ! in utero embryonic development GO:0001701 147 96 0,000 0,29356745 0,29549459 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,29356745 0,29536532 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,29356745 0,29523617 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,29612728 0,2976804 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,29612728 0,29755035 ! calcium ion transport GO:0006816 167 99 0,000 0,30121959 0,30253496 ! protein import GO:0017038 156 99 0,000 0,30121959 0,30240291 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,30121959 0,30227097 ! regulation of translation GO:0006417 151 100 0,000 0,30375213 0,30467942 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,30375213 0,3045466 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,30375213 0,3044139 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,30375213 0,30428132 ! divalent metal ion transport GO:0070838 171 100 0,000 0,30375213 0,30414885 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,30375213 0,30401649 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,30375213 0,30388426 ! protein localization in organelle GO:0033365 161 100 0,000 0,30375213 0,30375213