pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1236-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 3,000 1,004E-08 2,416E-05 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 2,334E-08 2,808E-05 ! androgen receptor signaling pathway GO:0030521 74 36 5,000 2,891E-08 2,318E-05 ! steroid hormone receptor signaling pathway GO:0030518 129 63 6,000 3,627E-08 2,181E-05 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 6,000 6,219E-08 2,993E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 1,332E-07 5,343E-05 ! regulation of mast cell proliferation GO:0070666 81 48 5,000 1,731E-07 5,949E-05 ! regulation of leukocyte proliferation GO:0070663 88 51 5,000 2,508E-07 7,543E-05 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of B cell proliferation GO:0030888 20 12 3,000 3,235E-07 8,648E-05 ! regulation of B cell activation GO:0050864 50 30 4,000 4,347E-07 1,046E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 5,000 1,299E-06 2,841E-04 ! negative regulation of kinase activity GO:0033673 131 68 5,000 1,418E-06 2,844E-04 ! negative regulation of transferase activity GO:0051348 140 72 5,000 1,991E-06 3,684E-04 ! regulation of T cell proliferation GO:0042129 71 41 4,000 2,184E-06 3,753E-04 ! regulation of T cell differentiation GO:0045580 70 41 4,000 2,184E-06 3,503E-04 ! nuclear migration GO:0007097 12 6 2,000 2,644E-06 3,976E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,644E-06 3,742E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 2,782E-06 3,719E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 4,593E-06 5,816E-04 ! positive regulation of B cell activation GO:0050871 38 22 3,000 4,593E-06 5,525E-04 ! macrophage differentiation GO:0030225 11 7 2,000 4,609E-06 5,281E-04 ! regulation of lymphocyte differentiation GO:0045619 81 48 4,000 4,847E-06 5,301E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 6,618E-06 6,923E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 7,347E-06 7,365E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 7,347E-06 7,071E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 7,347E-06 6,799E-04 ! vasculogenesis GO:0001570 46 25 3,000 7,847E-06 6,993E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 9,237E-06 7,937E-04 GO:0045936|negative regulation of phosphate metabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 1,005E-05 8,336E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,098E-05 8,805E-04 ! interphase GO:0051325 213 98 5,000 1,202E-05 9,325E-04 ! cell cycle arrest GO:0007050 213 100 5,000 1,349E-05 1,014E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,562E-05 1,139E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 2,000 1,562E-05 1,106E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 1,562E-05 1,074E-03 ! regulation of leukocyte migration GO:0002685 26 11 2,000 2,14E-05 1,43E-03 ! nucleus localization GO:0051647 19 11 2,000 2,14E-05 1,392E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 2,527E-05 1,6E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,843E-05 1,754E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 2,843E-05 1,71E-03 GO:0042130|negative regulation of T cell proliferation, ! aerobic respiration GO:0009060 55 36 3,000 3,497E-05 2,052E-03 ! regulation of protein stability GO:0031647 73 37 3,000 3,905E-05 2,237E-03 ! regulation of transcription factor activity GO:0051090 126 74 4,000 4,095E-05 2,291E-03 GO:0090046|regulation of transcription regulator activity, ! positive regulation of leukocyte proliferation GO:0070665 62 38 3,000 4,347E-05 2,377E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! catecholamine biosynthetic process GO:0042423 30 14 2,000 4,668E-05 2,496E-03 ! filopodium assembly GO:0046847 32 16 2,000 7,128E-05 3,728E-03 ! negative regulation of microtubule depolymerization GO:0007026 46 16 2,000 7,128E-05 3,649E-03 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 7,128E-05 3,573E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 2,000 7,128E-05 3,5E-03 ! ATP synthesis coupled electron transport GO:0042773 64 45 3,000 8,532E-05 4,105E-03 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of survival gene product expression GO:0045884 33 17 2,000 8,623E-05 4,068E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 8,623E-05 3,99E-03 ! microspike assembly GO:0030035 36 17 2,000 8,623E-05 3,914E-03 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 2,000 8,623E-05 3,842E-03 ! positive regulation of protein transport GO:0051222 72 46 3,000 9,307E-05 4,071E-03 ! regulation of DNA binding GO:0051101 155 88 4,000 9,399E-05 4,038E-03 ! regulation of immunoglobulin production GO:0002637 43 18 2,000 1,031E-04 4,351E-03 ! regulation of cell cycle process GO:0010564 149 90 4,000 1,046E-04 4,338E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,101E-04 4,489E-03 ! protein export from nucleus GO:0006611 36 19 2,000 1,219E-04 4,89E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 1,221E-04 4,818E-03 ! regulation of T cell activation GO:0050863 158 94 4,000 1,285E-04 4,986E-03 ! regulation of cell projection organization GO:0031344 121 50 3,000 1,293E-04 4,937E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 1,293E-04 4,86E-03 ! leukocyte differentiation GO:0002521 202 96 4,000 1,419E-04 5,252E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,429E-04 5,21E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,429E-04 5,132E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,429E-04 5,057E-03 ! respiratory electron transport chain GO:0022904 76 53 3,000 1,624E-04 5,663E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 1,661E-04 5,71E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 2,000 1,661E-04 5,629E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 1,661E-04 5,551E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! aging GO:0007568 103 55 3,000 1,876E-04 6,185E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 1,916E-04 6,23E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 1,916E-04 6,147E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,916E-04 6,066E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 1,916E-04 5,987E-03 ! protein stabilization GO:0050821 39 22 2,000 1,916E-04 5,911E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 2,156E-04 6,566E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 2,156E-04 6,484E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,195E-04 6,521E-03 ! establishment of organelle localization GO:0051656 109 59 3,000 2,464E-04 7,231E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 2,499E-04 7,245E-03 ! regulation of behavior GO:0050795 43 24 2,000 2,499E-04 7,159E-03 ! regulation of alpha-beta T cell activation GO:0046634 42 24 2,000 2,499E-04 7,075E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,605E-04 7,288E-03 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 2,605E-04 7,204E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,605E-04 7,123E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 2,605E-04 7,043E-03 ! response to protozoan GO:0001562 10 5 1,000 2,605E-04 6,964E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,605E-04 6,888E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 2,605E-04 6,813E-03 ! microvillus organization GO:0032528 7 5 1,000 2,605E-04 6,74E-03 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 1,000 2,605E-04 6,668E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 2,605E-04 6,598E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,605E-04 6,529E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 2,605E-04 6,462E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,605E-04 6,396E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 2,605E-04 6,331E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! decidualization GO:0046697 11 5 1,000 2,605E-04 6,268E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 2,605E-04 6,206E-03 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 2,605E-04 6,145E-03 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 1,000 2,605E-04 6,085E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,605E-04 6,027E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 2,605E-04 5,969E-03 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 1,000 2,605E-04 5,913E-03 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! stem cell division GO:0017145 11 5 1,000 2,605E-04 5,858E-03 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 2,605E-04 5,804E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 2,63E-04 5,805E-03 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 2,000 2,83E-04 6,189E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 2,985E-04 6,47E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 3,174E-04 6,819E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 3,187E-04 6,785E-03 ! positive regulation of MAPKKK cascade GO:0043410 47 26 2,000 3,187E-04 6,726E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 3,373E-04 7,056E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 2,000 3,571E-04 7,408E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,571E-04 7,344E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 3,571E-04 7,282E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 3,571E-04 7,221E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 3,579E-04 7,177E-03 ! cell projection assembly GO:0030031 120 66 3,000 3,795E-04 7,546E-03 ! thymic T cell selection GO:0045061 12 6 1,000 3,894E-04 7,68E-03 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 3,894E-04 7,618E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 3,894E-04 7,556E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 3,894E-04 7,496E-03 ! regulation of collagen metabolic process GO:0010712 9 6 1,000 3,894E-04 7,437E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 3,894E-04 7,378E-03 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 3,894E-04 7,32E-03 ! neutrophil homeostasis GO:0001780 10 6 1,000 3,894E-04 7,264E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 3,894E-04 7,208E-03 ! negative regulation of axon extension GO:0030517 21 6 1,000 3,894E-04 7,153E-03 ! triglyceride catabolic process GO:0019433 10 6 1,000 3,894E-04 7,098E-03 ! organ or tissue specific immune response GO:0002251 7 6 1,000 3,894E-04 7,045E-03 ! maternal placenta development GO:0001893 12 6 1,000 3,894E-04 6,993E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,894E-04 6,941E-03 ! positive regulation of T cell differentiation GO:0045582 42 28 2,000 3,985E-04 7,05E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 4,02E-04 7,06E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 4,428E-04 7,72E-03 ! catechol metabolic process GO:0009712 54 29 2,000 4,428E-04 7,665E-03 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 2,000 4,428E-04 7,61E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 4,428E-04 7,556E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 4,498E-04 7,622E-03 ! phenol metabolic process GO:0018958 55 30 2,000 4,902E-04 8,247E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 4,902E-04 8,19E-03 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 2,000 5,406E-04 8,971E-03 ! positive regulation of T cell proliferation GO:0042102 52 31 2,000 5,406E-04 8,909E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 5,406E-04 8,849E-03 GO:0043433|negative regulation of transcription factor activity, ! prostate gland development GO:0030850 13 7 1,000 5,434E-04 8,834E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,434E-04 8,774E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,434E-04 8,716E-03 ! mRNA stabilization GO:0048255 18 7 1,000 5,434E-04 8,658E-03 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 5,434E-04 8,601E-03 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 5,434E-04 8,545E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,434E-04 8,489E-03 ! positive regulation of isotype switching GO:0045830 15 7 1,000 5,434E-04 8,435E-03 GO:0045911|positive regulation of DNA recombination, ! glycerol ether catabolic process GO:0044269 12 7 1,000 5,434E-04 8,381E-03 GO:0046464|acylglycerol catabolic process, ! regulation of meiosis GO:0040020 12 7 1,000 5,434E-04 8,327E-03 GO:0051445|regulation of meiotic cell cycle, ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 1,000 5,434E-04 8,274E-03 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 5,434E-04 8,222E-03 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 5,434E-04 8,171E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 5,434E-04 8,12E-03 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 5,434E-04 8,07E-03 ! organelle localization GO:0051640 136 74 3,000 5,869E-04 8,663E-03 ! spindle organization GO:0007051 46 32 2,000 5,943E-04 8,719E-03 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 2,000 5,943E-04 8,666E-03 ! positive regulation of lymphocyte activation GO:0051251 127 77 3,000 6,821E-04 9,886E-03 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 2,000 7,116E-04 0,01025264 ! biogenic amine biosynthetic process GO:0042401 62 34 2,000 7,116E-04 0,01019161 ! negative regulation of organelle organization GO:0010639 161 78 3,000 7,161E-04 0,01019494 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 7,221E-04 0,01021919 ! neutral lipid catabolic process GO:0046461 13 8 1,000 7,221E-04 0,01015942 ! succinate metabolic process GO:0006105 14 8 1,000 7,221E-04 0,01010036 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,221E-04 0,01004197 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,221E-04 9,984E-03 ! glycerolipid catabolic process GO:0046503 13 8 1,000 7,221E-04 9,927E-03 ! ER overload response GO:0006983 12 8 1,000 7,221E-04 9,871E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,221E-04 9,815E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,221E-04 9,76E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,221E-04 9,705E-03 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 7,221E-04 9,651E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 7,221E-04 9,598E-03 ! myeloid cell homeostasis GO:0002262 13 8 1,000 7,221E-04 9,545E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 7,221E-04 9,493E-03 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 7,221E-04 9,442E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 7,221E-04 9,391E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 7,221E-04 9,34E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 7,513E-04 9,666E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 7,513E-04 9,615E-03 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 7,754E-04 9,871E-03 ! regulation of microtubule-based process GO:0032886 78 35 2,000 7,754E-04 9,819E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 8,253E-04 0,01039669 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 2,000 8,427E-04 0,01056056 ! negative regulation of cell activation GO:0050866 65 36 2,000 8,427E-04 0,01050585 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 8,642E-04 0,01071815 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 9,137E-04 0,01127306 ! negative regulation of DNA binding GO:0043392 68 37 2,000 9,137E-04 0,01121555 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 9,137E-04 0,01115862 ! induction of positive chemotaxis GO:0050930 15 9 1,000 9,252E-04 0,0112428 ! microtubule bundle formation GO:0001578 21 9 1,000 9,252E-04 0,01118631 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,252E-04 0,01113037 ! T cell selection GO:0045058 23 9 1,000 9,252E-04 0,011075 ! phosphagen metabolic process GO:0006599 12 9 1,000 9,252E-04 0,01102017 GO:0006600|creatine metabolic process, ! receptor clustering GO:0043113 18 9 1,000 9,252E-04 0,01096589 ! motor axon guidance GO:0008045 16 9 1,000 9,252E-04 0,01091213 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 9,252E-04 0,0108589 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 9,252E-04 0,01080619 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 15 9 1,000 9,252E-04 0,01075398 ! regulation of telomere maintenance GO:0032204 14 9 1,000 9,252E-04 0,01070228 ! negative regulation of growth GO:0045926 155 84 3,000 9,458E-04 0,01088841 ! regulation of ligase activity GO:0051340 142 84 3,000 9,458E-04 0,01083656 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 9,882E-04 0,01126874 ! nucleus organization GO:0006997 67 38 2,000 9,882E-04 0,01121559 ! positive regulation of cell activation GO:0050867 145 85 3,000 9,886E-04 0,01116709 GO:0002696|positive regulation of leukocyte activation, ! oxidative phosphorylation GO:0006119 133 86 3,000 1,033E-03 0,01161089 ! regulation of protein transport GO:0051223 154 87 3,000 1,078E-03 0,01206584 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 3,000 1,125E-03 0,01253202 ! gland development GO:0048732 206 88 3,000 1,125E-03 0,01247427 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 2,000 1,149E-03 0,01267811 ! negative regulation of binding GO:0051100 72 40 2,000 1,149E-03 0,01262022 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,153E-03 0,01260543 ! lung alveolus development GO:0048286 26 10 1,000 1,153E-03 0,01254839 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 1,153E-03 0,01249187 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 1,153E-03 0,01243585 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 1,153E-03 0,01238034 ! regulation of bone resorption GO:0045124 25 10 1,000 1,153E-03 0,01232531 ! negative regulation of axonogenesis GO:0050771 32 10 1,000 1,153E-03 0,01227078 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 1,153E-03 0,01221672 ! regulation of B cell differentiation GO:0045577 19 10 1,000 1,153E-03 0,01216314 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 1,153E-03 0,01211002 ! salivary gland development GO:0007431 27 10 1,000 1,153E-03 0,01205737 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 1,153E-03 0,01200517 ! blastocyst formation GO:0001825 17 10 1,000 1,153E-03 0,01195343 ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,153E-03 0,01190213 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,153E-03 0,01185126 ! localization within membrane GO:0051668 20 10 1,000 1,153E-03 0,01180083 ! T cell differentiation GO:0030217 81 41 2,000 1,235E-03 0,01258827 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 1,325E-03 0,01344874 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 2,000 1,325E-03 0,01339224 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,325E-03 0,0133362 ! neuron fate specification GO:0048665 17 11 1,000 1,404E-03 0,01407507 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 1,404E-03 0,01401667 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,404E-03 0,01395875 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,404E-03 0,01390131 ! T cell proliferation GO:0042098 26 11 1,000 1,404E-03 0,01384433 ! blood vessel remodeling GO:0001974 29 11 1,000 1,404E-03 0,01378783 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,404E-03 0,01373178 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,404E-03 0,01367618 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,404E-03 0,01362104 ! ventral spinal cord development GO:0021517 21 11 1,000 1,404E-03 0,01356634 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,404E-03 0,01351207 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 1,404E-03 0,01345824 ! DNA methylation GO:0006306 19 11 1,000 1,404E-03 0,01340483 GO:0006305|DNA alkylation, ! regulation of isotype switching GO:0045191 22 11 1,000 1,404E-03 0,01335185 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 1,404E-03 0,01329928 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 1,404E-03 0,01324713 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 1,404E-03 0,01319538 ! sequestering of metal ion GO:0051238 14 11 1,000 1,404E-03 0,01314404 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 1,419E-03 0,01323081 ! transcription initiation GO:0006352 153 94 3,000 1,437E-03 0,01334614 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 2,000 1,517E-03 0,01403686 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 1,613E-03 0,01486972 ! regulation of protein localization GO:0032880 176 97 3,000 1,613E-03 0,01481296 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 1,619E-03 0,01481219 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,619E-03 0,01475608 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 1,679E-03 0,01524506 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 1,679E-03 0,01518775 ! cartilage condensation GO:0001502 20 12 1,000 1,679E-03 0,01513086 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 1,679E-03 0,01507441 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,679E-03 0,01501837 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,679E-03 0,01496274 ! focal adhesion formation GO:0048041 35 12 1,000 1,679E-03 0,01490753 ! mitotic spindle organization GO:0007052 21 12 1,000 1,679E-03 0,01485272 ! entry into host cell GO:0030260 32 12 1,000 1,679E-03 0,01479832 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 16 12 1,000 1,679E-03 0,01474431 ! histone acetylation GO:0016573 26 12 1,000 1,679E-03 0,01469069 ! gland morphogenesis GO:0022612 29 12 1,000 1,679E-03 0,01463747 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,679E-03 0,01458462 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,679E-03 0,01453216 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,726E-03 0,01488089 ! response to insulin stimulus GO:0032868 95 46 2,000 1,726E-03 0,01482775 ! positive regulation of DNA binding GO:0043388 73 47 2,000 1,836E-03 0,01572321 ! regulation of adaptive immune response GO:0002819 84 47 2,000 1,836E-03 0,01566746 ! cellular component disassembly GO:0022411 86 48 2,000 1,951E-03 0,0165905 ! activation of caspase activity GO:0006919 84 48 2,000 1,951E-03 0,01653209 ! regulation of chemokine production GO:0032642 18 13 1,000 1,978E-03 0,01669603 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,978E-03 0,01663765 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 22 13 1,000 1,978E-03 0,01657968 ! plasma membrane organization GO:0007009 24 13 1,000 1,978E-03 0,01652212 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,978E-03 0,01646495 ! exocrine system development GO:0035272 32 13 1,000 1,978E-03 0,01640817 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,978E-03 0,01635178 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 1,978E-03 0,01629579 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 1,978E-03 0,01624017 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,978E-03 0,01618493 ! embryonic placenta development GO:0001892 23 13 1,000 1,978E-03 0,01613007 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,978E-03 0,01607557 ! regulation of protein complex disassembly GO:0043244 113 49 2,000 2,071E-03 0,01677636 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,3E-03 0,01856614 ! regulation of S phase GO:0033261 23 14 1,000 2,3E-03 0,01850405 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,3E-03 0,01844237 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 2,3E-03 0,0183811 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,3E-03 0,01832024 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 2,3E-03 0,01825977 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 2,3E-03 0,01819971 ! regulation of RNA stability GO:0043487 32 14 1,000 2,3E-03 0,01814004 ! regulation of axon extension GO:0030516 37 14 1,000 2,3E-03 0,01808076 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,3E-03 0,01802186 ! positive regulation of binding GO:0051099 78 51 2,000 2,323E-03 0,01814872 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 2,323E-03 0,01808998 ! regulation of angiogenesis GO:0045765 114 52 2,000 2,456E-03 0,01906398 ! response to UV GO:0009411 104 53 2,000 2,594E-03 0,02006745 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 2,644E-03 0,02039224 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 2,644E-03 0,02032709 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 2,644E-03 0,02026235 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 2,644E-03 0,02019803 ! negative regulation of cytoskeleton organization GO:0051494 124 54 2,000 2,736E-03 0,02083345 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 2,000 2,736E-03 0,02076773 ! positive regulation of caspase activity GO:0043280 95 55 2,000 2,883E-03 0,02181488 GO:0010952|positive regulation of peptidase activity, ! nuclear export GO:0051168 97 55 2,000 2,883E-03 0,0217465 ! negative regulation of immune response GO:0050777 35 16 1,000 3,012E-03 0,02264622 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,012E-03 0,02257567 ! neuron recognition GO:0008038 35 16 1,000 3,012E-03 0,02250556 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 3,012E-03 0,02243589 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,012E-03 0,02236664 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 1,000 3,012E-03 0,02229782 ! regulation of bone remodeling GO:0046850 137 57 2,000 3,192E-03 0,02355601 ! regulation of intracellular transport GO:0032386 101 57 2,000 3,192E-03 0,02348397 ! maintenance of location GO:0051235 118 57 2,000 3,192E-03 0,02341237 ! regulation of tissue remodeling GO:0034103 140 58 2,000 3,353E-03 0,02452236 ! positive regulation of cell killing GO:0031343 32 17 1,000 3,402E-03 0,02480415 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 3,402E-03 0,02472921 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,402E-03 0,02465473 ! signal complex assembly GO:0007172 41 17 1,000 3,402E-03 0,02458069 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 3,402E-03 0,02450709 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 3,402E-03 0,02443394 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 3,402E-03 0,02436122 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 3,402E-03 0,02428893 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 3,402E-03 0,02421707 GO:0002712|regulation of B cell mediated immunity, ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 3,402E-03 0,02414563 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 3,402E-03 0,02407462 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 3,402E-03 0,02400402 ! skeletal system morphogenesis GO:0048705 105 59 2,000 3,52E-03 0,02476111 ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 3,52E-03 0,02468892 ! DNA catabolic process GO:0006308 86 59 2,000 3,52E-03 0,02461715 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 3,814E-03 0,02660156 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,814E-03 0,02652468 ! cell-substrate junction assembly GO:0007044 54 18 1,000 3,814E-03 0,02644824 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 3,814E-03 0,02637224 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 3,814E-03 0,02629667 ! regulation of protein complex assembly GO:0043254 117 61 2,000 3,867E-03 0,02658616 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 3,867E-03 0,02651041 ! positive regulation of translation GO:0045727 30 19 1,000 4,249E-03 0,02904185 ! lipid phosphorylation GO:0046834 35 19 1,000 4,249E-03 0,02895958 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 4,249E-03 0,02887777 ! actin filament bundle formation GO:0051017 42 19 1,000 4,249E-03 0,02879643 ! neuromuscular junction development GO:0007528 34 19 1,000 4,249E-03 0,02871554 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 4,249E-03 0,0286351 ! peptide cross-linking GO:0018149 37 19 1,000 4,249E-03 0,02855512 ! G1 phase GO:0051318 40 19 1,000 4,249E-03 0,02847558 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 4,249E-03 0,02839648 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,249E-03 0,02831782 ! proximal/distal pattern formation GO:0009954 32 19 1,000 4,249E-03 0,02823959 ! peptide hormone secretion GO:0030072 31 19 1,000 4,249E-03 0,0281618 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 4,705E-03 0,03109995 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,705E-03 0,03101475 ! response to alkaloid GO:0043279 38 20 1,000 4,705E-03 0,03093001 ! pancreas development GO:0031016 35 20 1,000 4,705E-03 0,03084573 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 4,705E-03 0,03076191 ! peptide secretion GO:0002790 35 20 1,000 4,705E-03 0,03067854 ! peptidyl-serine modification GO:0018209 43 20 1,000 4,705E-03 0,03059563 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 4,705E-03 0,03051316 ! negative regulation of translation GO:0017148 29 20 1,000 4,705E-03 0,03043114 ! actin filament organization GO:0007015 148 66 2,000 4,826E-03 0,03113142 ! activation of MAPK activity GO:0000187 115 67 2,000 5,034E-03 0,03238233 ! lung development GO:0030324 144 67 2,000 5,034E-03 0,03229598 ! homeostasis of number of cells GO:0048872 114 67 2,000 5,034E-03 0,03221009 ! positive regulation of T cell activation GO:0050870 109 67 2,000 5,034E-03 0,03212465 ! regulation of cell killing GO:0031341 42 21 1,000 5,183E-03 0,03298923 ! hormone secretion GO:0046879 38 21 1,000 5,183E-03 0,03290219 ! cell aging GO:0007569 44 21 1,000 5,183E-03 0,03281561 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 5,183E-03 0,03272948 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 5,183E-03 0,0326438 ! DNA modification GO:0006304 34 21 1,000 5,183E-03 0,03255857 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 5,183E-03 0,03247378 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 5,183E-03 0,03238943 ! cell cycle checkpoint GO:0000075 137 69 2,000 5,464E-03 0,03406032 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 5,464E-03 0,03397231 ! urogenital system development GO:0001655 137 69 2,000 5,464E-03 0,03388475 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 5,682E-03 0,0351435 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 5,682E-03 0,03505338 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 5,682E-03 0,03496373 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 5,682E-03 0,03487454 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 5,682E-03 0,0347858 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 5,682E-03 0,03469751 ! respiratory tube development GO:0030323 150 70 2,000 5,688E-03 0,034645 ! reproductive structure development GO:0048608 113 71 2,000 5,917E-03 0,03594766 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 5,917E-03 0,03585711 ! regulation of immune effector process GO:0002697 137 71 2,000 5,917E-03 0,03576702 ! regulation of caspase activity GO:0043281 122 72 2,000 6,151E-03 0,03708989 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 6,151E-03 0,03699717 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 6,151E-03 0,0369049 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 6,151E-03 0,0368131 ! respiratory system development GO:0060541 153 72 2,000 6,151E-03 0,03672175 ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,202E-03 0,03693688 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 6,202E-03 0,03684568 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,202E-03 0,03675492 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 6,202E-03 0,03666462 ! leukocyte adhesion GO:0007159 50 23 1,000 6,202E-03 0,03657475 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,202E-03 0,03648533 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 6,202E-03 0,03639634 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 6,202E-03 0,03630778 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,202E-03 0,03621966 ! sex determination GO:0007530 47 23 1,000 6,202E-03 0,03613196 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 6,202E-03 0,03604468 ! platelet activation GO:0030168 37 23 1,000 6,202E-03 0,03595783 ! hormone transport GO:0009914 40 23 1,000 6,202E-03 0,03587139 ! negative regulation of catabolic process GO:0009895 50 23 1,000 6,202E-03 0,03578537 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 6,202E-03 0,03569976 ! meiosis GO:0007126 121 74 2,000 6,636E-03 0,03810414 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 6,636E-03 0,03801342 ! eye development GO:0001654 143 74 2,000 6,636E-03 0,03792313 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 6,743E-03 0,03844649 ! spinal cord development GO:0021510 47 24 1,000 6,743E-03 0,0383556 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 6,743E-03 0,03826514 ! lymphocyte proliferation GO:0046651 48 24 1,000 6,743E-03 0,0381751 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 6,743E-03 0,03808549 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 6,743E-03 0,0379963 ! leukocyte homeostasis GO:0001776 44 24 1,000 6,743E-03 0,03790752 ! cell-matrix adhesion GO:0007160 163 75 2,000 6,887E-03 0,0386223 ! meiotic cell cycle GO:0051321 122 75 2,000 6,887E-03 0,03853248 ! lymphocyte differentiation GO:0030098 167 75 2,000 6,887E-03 0,03844307 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 7,305E-03 0,04068527 ! myelination GO:0042552 45 25 1,000 7,305E-03 0,04059131 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 7,305E-03 0,04049778 ! receptor metabolic process GO:0043112 46 25 1,000 7,305E-03 0,04040468 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,305E-03 0,04031201 ! negative regulation of cell development GO:0010721 73 25 1,000 7,305E-03 0,04021976 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 7,305E-03 0,04012794 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 7,305E-03 0,04003653 ! somitogenesis GO:0001756 43 25 1,000 7,305E-03 0,03994554 ! immunoglobulin production GO:0002377 55 25 1,000 7,305E-03 0,03985496 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 36 25 1,000 7,305E-03 0,03976479 ! positive regulation of ligase activity GO:0051351 124 77 2,000 7,405E-03 0,04021642 ! blood coagulation GO:0007596 146 78 2,000 7,672E-03 0,04157565 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 7,672E-03 0,04148223 ! initiation of viral infection GO:0019059 57 26 1,000 7,887E-03 0,04254891 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 7,887E-03 0,04245372 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 7,887E-03 0,04235896 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 7,887E-03 0,04226462 ! cellular response to oxidative stress GO:0034599 39 26 1,000 7,887E-03 0,0421707 ! positive regulation of nuclear division GO:0051785 40 26 1,000 7,887E-03 0,04207719 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 7,887E-03 0,0419841 ! blastocyst development GO:0001824 49 26 1,000 7,887E-03 0,04189142 ! leukocyte proliferation GO:0070661 52 26 1,000 7,887E-03 0,04179915 GO:0032943|mononuclear cell proliferation, ! regulation of peptidase activity GO:0052547 134 79 2,000 7,946E-03 0,04201518 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 8,49E-03 0,04479433 ! neuron fate commitment GO:0048663 48 27 1,000 8,49E-03 0,04469631 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 8,49E-03 0,04459872 ! protein amino acid acylation GO:0043543 55 27 1,000 8,49E-03 0,04450156 ! male gonad development GO:0008584 44 27 1,000 8,49E-03 0,04440482 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 8,49E-03 0,04430849 ! T cell activation GO:0042110 168 81 2,000 8,509E-03 0,04431294 ! response to hypoxia GO:0001666 171 81 2,000 8,509E-03 0,04421723 ! cell-substrate adhesion GO:0031589 171 81 2,000 8,509E-03 0,04412193 ! regulation of neuron differentiation GO:0045664 167 81 2,000 8,509E-03 0,04402705 ! response to oxygen levels GO:0070482 176 83 2,000 9,095E-03 0,04696002 ! dendrite development GO:0016358 59 28 1,000 9,112E-03 0,04694584 ! negative regulation of protein modification process GO:0031400 60 28 1,000 9,112E-03 0,04684553 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 9,112E-03 0,04674565 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 9,112E-03 0,04664619 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 9,112E-03 0,04654715 ! hemostasis GO:0007599 158 84 2,000 9,397E-03 0,04790166 ! negative regulation of transport GO:0051051 153 84 2,000 9,397E-03 0,04780038 ! one-carbon metabolic process GO:0006730 154 85 2,000 9,705E-03 0,04926105 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 9,754E-03 0,04940794 ! immune response-activating signal transduction GO:0002757 47 29 1,000 9,754E-03 0,04930414 GO:0002764|immune response-regulating signal transduction, ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 9,754E-03 0,04920077 ! amine biosynthetic process GO:0009309 138 86 2,000 0,01001824 0,05042656 ! mitochondrion organization GO:0007005 148 86 2,000 0,01001824 0,05032129 ! cell junction assembly GO:0034329 78 30 1,000 0,01041599 0,05221015 ! acute-phase response GO:0006953 49 30 1,000 0,01041599 0,05210161 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01041599 0,05199351 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01041599 0,05188587 GO:0008366|axon ensheathment, ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01066268 0,05300496 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,0109937 0,05453782 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,0109937 0,05442561 ! peptide transport GO:0015833 55 31 1,000 0,01109705 0,05482444 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01109705 0,05471209 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01109705 0,05460021 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01109705 0,05448878 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01109705 0,0543778 ! ossification GO:0001503 188 90 2,000 0,01133062 0,05540949 ! sex differentiation GO:0007548 145 90 2,000 0,01133062 0,0552971 ! bone development GO:0060348 189 91 2,000 0,01167345 0,05685491 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,01179723 0,0573417 ! metanephros development GO:0001656 74 32 1,000 0,01179723 0,05722609 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01179723 0,05711094 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,01179723 0,05699626 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01179723 0,05688204 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01179723 0,05676828 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01237692 0,05943886 ! cell fate specification GO:0001708 52 33 1,000 0,01251632 0,0599886 ! leukocyte chemotaxis GO:0030595 50 33 1,000 0,01251632 0,05986934 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01251632 0,05975055 ! biogenic amine metabolic process GO:0006576 155 94 2,000 0,01273759 0,0606864 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01325412 0,06302254 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01325412 0,06289824 ! placenta development GO:0001890 53 34 1,000 0,01325412 0,06277442 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01325412 0,0626511 ! negative regulation of secretion GO:0051048 63 35 1,000 0,0140104 0,06609613 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,0140104 0,06596679 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,0140104 0,06583795 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 0,0140104 0,06570961 ! response to virus GO:0009615 160 98 2,000 0,01424014 0,06665714 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01463081 0,06835287 GO:0060538|skeletal muscle organ development, ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01478497 0,06893922 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01478497 0,06880588 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 1,000 0,01478497 0,06867305 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01478497 0,06854073 ! RNA export from nucleus GO:0006405 56 37 1,000 0,01557762 0,07207644 ! meiosis I GO:0007127 65 37 1,000 0,01557762 0,0719381 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01557762 0,07180028 ! tissue remodeling GO:0048771 76 37 1,000 0,01557762 0,071663 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,01557762 0,07152624 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01557762 0,07139 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,01638814 0,07496171 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01638814 0,07481947 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,01638814 0,07467777 ! glucan metabolic process GO:0044042 62 38 1,000 0,01638814 0,0745366 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01721633 0,07815565 ! ear morphogenesis GO:0042471 60 39 1,000 0,01721633 0,07800846 ! organic ether metabolic process GO:0018904 55 39 1,000 0,01721633 0,07786183 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01721633 0,07771575 ! segmentation GO:0035282 67 39 1,000 0,01721633 0,07757021 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,01721633 0,07742522 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01721633 0,07728077 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,01806199 0,08092581 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01806199 0,08077539 ! maintenance of protein location GO:0045185 91 40 1,000 0,01806199 0,08062553 ! cytokinesis GO:0000910 72 40 1,000 0,01806199 0,08047622 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,01892493 0,08416522 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01892493 0,08400993 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01980494 0,08775448 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,01980494 0,08759317 ! regulation of protein secretion GO:0050708 71 42 1,000 0,01980494 0,08743245 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01980494 0,08727231 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02070183 0,09105776 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02070183 0,09089159 ! glucose transport GO:0015758 65 43 1,000 0,02070183 0,09072603 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02070183 0,09056108 ! hexose transport GO:0008645 67 44 1,000 0,02161539 0,09438592 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,02161539 0,09421493 ! double-strand break repair GO:0006302 81 44 1,000 0,02161539 0,09404456 ! biopolymer methylation GO:0043414 84 44 1,000 0,02161539 0,0938748 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02161539 0,09370566 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02161539 0,09353712 ! glycolysis GO:0006096 65 45 1,000 0,02254545 0,09738665 ! leukocyte migration GO:0050900 68 45 1,000 0,02254545 0,09721212 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02254545 0,09703822 ! cell growth GO:0016049 84 45 1,000 0,02254545 0,09686493 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02349181 0,10075098 ! pigmentation GO:0043473 100 46 1,000 0,02349181 0,10057171 ! positive regulation of defense response GO:0031349 76 47 1,000 0,02445428 0,1045062 ! endosome transport GO:0016197 108 47 1,000 0,02445428 0,10432091 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02445428 0,10413627 ! methylation GO:0032259 90 47 1,000 0,02445428 0,10395228 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,02543266 0,10792061 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02547113 0,10789357 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02547113 0,10770395 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02547113 0,107515 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02547113 0,10732671 ! neuron fate determination GO:0048664 7 5 0,000 0,02547113 0,10713907 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02547113 0,10695209 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02547113 0,10676576 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02547113 0,10658008 ! polyol transport GO:0015791 12 5 0,000 0,02547113 0,10639505 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02547113 0,10621066 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02547113 0,1060269 ! response to superoxide GO:0000303 10 5 0,000 0,02547113 0,10584378 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02547113 0,10566129 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02547113 0,10547943 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02547113 0,10529819 ! female meiosis GO:0007143 7 5 0,000 0,02547113 0,10511758 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02547113 0,10493758 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02547113 0,1047582 ! cobalt ion transport GO:0006824 11 5 0,000 0,02547113 0,10457943 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02547113 0,10440128 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02547113 0,10422372 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02547113 0,10404677 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02547113 0,10387042 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02547113 0,10369467 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02547113 0,10351951 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02547113 0,10334494 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02547113 0,10317096 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02547113 0,10299756 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02547113 0,10282475 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02547113 0,10265251 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02547113 0,10248085 ! negative chemotaxis GO:0050919 14 5 0,000 0,02547113 0,10230976 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02547113 0,10213925 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02547113 0,1019693 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02547113 0,10179991 ! behavioral response to pain GO:0048266 9 5 0,000 0,02547113 0,10163109 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02547113 0,10146283 ! Notch receptor processing GO:0007220 8 5 0,000 0,02547113 0,10129512 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02547113 0,10112797 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02547113 0,10096137 ! micturition GO:0060073 9 5 0,000 0,02547113 0,10079531 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02547113 0,1006298 ! copulation GO:0007620 9 5 0,000 0,02547113 0,10046483 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02547113 0,10030041 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02547113 0,10013652 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02547113 0,09997316 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02547113 0,09981034 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02547113 0,09964805 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02547113 0,09948628 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02547113 0,09932504 ! grooming behavior GO:0007625 6 5 0,000 0,02547113 0,09916432 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02547113 0,09900412 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02547113 0,09884443 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02547113 0,09868526 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02547113 0,09852661 ! lymph vessel development GO:0001945 10 5 0,000 0,02547113 0,09836846 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02547113 0,09821082 ! endochondral ossification GO:0001958 16 5 0,000 0,02547113 0,09805368 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02547113 0,09789704 ! parathyroid gland development GO:0060017 13 5 0,000 0,02547113 0,09774091 ! anagen GO:0042640 6 5 0,000 0,02547113 0,09758527 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02547113 0,09743013 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02547113 0,09727547 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02547113 0,09712131 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02547113 0,09696764 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02547113 0,09681445 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02547113 0,09666175 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02547113 0,09650953 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02547113 0,09635778 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02547113 0,09620651 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02547113 0,09605572 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02547113 0,0959054 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02547113 0,09575554 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02547113 0,09560616 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02547113 0,09545724 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02547113 0,09530879 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02547113 0,09516079 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02547113 0,09501325 ! histidine catabolic process GO:0006548 6 5 0,000 0,02547113 0,09486617 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02547113 0,09471955 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02547113 0,09457338 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02547113 0,09442766 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02547113 0,09428238 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02547113 0,09413756 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02547113 0,09399317 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02547113 0,09384923 ! polyol catabolic process GO:0046174 7 5 0,000 0,02547113 0,09370573 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02547113 0,09356267 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02547113 0,09342004 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02547113 0,09327785 ! muscle cell migration GO:0014812 8 5 0,000 0,02547113 0,09313609 ! mitochondrial fission GO:0000266 8 5 0,000 0,02547113 0,09299476 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02547113 0,09285386 ! mRNA transcription GO:0009299 9 5 0,000 0,02547113 0,09271339 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02547113 0,09257334 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02547113 0,09243371 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02547113 0,0922945 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02547113 0,09215571 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02547113 0,09201734 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02547113 0,09187938 ! response to food GO:0032094 6 5 0,000 0,02547113 0,09174184 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02547113 0,09160471 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02547113 0,09146798 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02547113 0,09133167 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02547113 0,09119576 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02547113 0,09106025 ! forebrain neuron development GO:0021884 13 5 0,000 0,02547113 0,09092515 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02547113 0,09079044 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02547113 0,09065614 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02547113 0,09052223 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02547113 0,09038872 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02547113 0,09025559 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02547113 0,09012287 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02547113 0,08999053 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02547113 0,08985858 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02547113 0,08972701 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02547113 0,08959583 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02547113 0,08946503 ! basic amino acid transport GO:0015802 11 5 0,000 0,02547113 0,08933462 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02547113 0,08920458 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02547113 0,08907493 ! depyrimidination GO:0045008 10 5 0,000 0,02547113 0,08894564 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02547113 0,08881674 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02547113 0,0886882 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02547113 0,08856004 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02547113 0,08843225 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02547113 0,08830483 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02547113 0,08817777 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02547113 0,08805108 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02547113 0,08792475 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02547113 0,08779878 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02547113 0,08767317 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02547113 0,08754793 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02547113 0,08742304 ! response to arsenic GO:0046685 10 5 0,000 0,02547113 0,0872985 ! mast cell degranulation GO:0043303 7 5 0,000 0,02547113 0,08717432 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02547113 0,0870505 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02547113 0,08692702 ! response to cadmium ion GO:0046686 7 5 0,000 0,02547113 0,08680389 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02547113 0,08668112 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02547113 0,08655868 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02547113 0,0864366 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02547113 0,08631486 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02547113 0,08619346 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02547113 0,0860724 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02547113 0,08595168 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02547113 0,0858313 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02547113 0,08571126 ! neural tube patterning GO:0021532 7 5 0,000 0,02547113 0,08559155 ! embryonic cleavage GO:0040016 6 5 0,000 0,02547113 0,08547217 ! peroxisome fission GO:0016559 5 5 0,000 0,02547113 0,08535313 ! histone demethylation GO:0016577 10 5 0,000 0,02547113 0,08523442 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02547113 0,08511604 ! mitotic recombination GO:0006312 9 5 0,000 0,02547113 0,08499799 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02547113 0,08488026 ! metaphase plate congression GO:0051310 7 5 0,000 0,02547113 0,08476286 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02547113 0,08464579 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02547113 0,08452903 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02547113 0,0844126 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02547113 0,08429649 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02547113 0,0841807 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02547113 0,08406522 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02547113 0,08395007 ! plasminogen activation GO:0031639 5 5 0,000 0,02547113 0,08383522 ! B cell homeostasis GO:0001782 13 5 0,000 0,02547113 0,0837207 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02547113 0,08360648 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02547113 0,08349257 ! metaphase GO:0051323 8 5 0,000 0,02547113 0,08337898 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02547113 0,08326569 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02547113 0,08315271 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02547113 0,08304004 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02547113 0,08292767 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02547113 0,08281561 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02547113 0,08270384 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02547113 0,08259238 ! response to redox state GO:0051775 5 5 0,000 0,02547113 0,08248122 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02547113 0,08237036 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02547113 0,0822598 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02547113 0,08214953 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02547113 0,08203956 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02547113 0,08192988 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02547113 0,08182049 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02547113 0,0817114 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02547113 0,08160259 ! striatum development GO:0021756 9 5 0,000 0,02547113 0,08149408 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02547113 0,08138585 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02547113 0,08127792 ! glial cell migration GO:0008347 11 5 0,000 0,02547113 0,08117026 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02547113 0,0810629 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02547113 0,08095581 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02547113 0,08084901 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02547113 0,08074249 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02547113 0,08063625 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02547113 0,08053029 ! neuroprotection GO:0043526 6 5 0,000 0,02547113 0,0804246 ! neural plate development GO:0001840 8 5 0,000 0,02547113 0,0803192 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02547113 0,08021407 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02547113 0,08010921 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02547113 0,08000463 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02547113 0,07990032 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02547113 0,07979629 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02547113 0,07969252 ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02547113 0,07958902 ! spindle assembly GO:0051225 6 5 0,000 0,02547113 0,0794858 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02547113 0,07938284 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02547113 0,07928014 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02547113 0,07917771 ! drug metabolic process GO:0017144 6 5 0,000 0,02547113 0,07907555 ! organ regeneration GO:0031100 7 5 0,000 0,02547113 0,07897365 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02547113 0,07887201 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02547113 0,07877063 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02547113 0,07866951 ! regulation of action potential GO:0001508 95 49 1,000 0,02642678 0,08151645 ! endocrine system development GO:0035270 104 49 1,000 0,02642678 0,08141208 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,02642678 0,08130797 ! neuromuscular process GO:0050905 99 50 1,000 0,02743644 0,08430662 ! regulation of ossification GO:0030278 117 50 1,000 0,02743644 0,08419909 ! histone modification GO:0016570 91 50 1,000 0,02743644 0,08409183 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,02743644 0,08398484 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,02743644 0,08387813 ! viral infectious cycle GO:0019058 99 51 1,000 0,02846147 0,0869014 ! regulation of cell shape GO:0008360 125 51 1,000 0,02846147 0,08679126 ! positive regulation of growth GO:0045927 90 52 1,000 0,02950168 0,08984942 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02950168 0,08973583 ! cartilage development GO:0051216 90 52 1,000 0,02950168 0,08962253 ! synapse organization GO:0050808 85 52 1,000 0,02950168 0,08950951 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03048747 0,09238395 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03048747 0,09226775 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03048747 0,09215183 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03048747 0,09203621 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03048747 0,09192088 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03048747 0,09180583 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03048747 0,09169107 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03048747 0,0915766 ! sleep GO:0030431 13 6 0,000 0,03048747 0,09146242 ! response to oxygen radical GO:0000305 11 6 0,000 0,03048747 0,09134852 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03048747 0,0912349 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03048747 0,09112156 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03048747 0,09100851 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03048747 0,09089574 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03048747 0,09078324 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03048747 0,09067102 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03048747 0,09055908 ! forebrain regionalization GO:0021871 8 6 0,000 0,03048747 0,09044742 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03048747 0,09033603 ! male meiosis GO:0007140 7 6 0,000 0,03048747 0,09022492 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03048747 0,09011408 ! response to zinc ion GO:0010043 9 6 0,000 0,03048747 0,09000351 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03048747 0,08989321 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03048747 0,08978318 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03048747 0,08967342 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03048747 0,08956393 ! malate metabolic process GO:0006108 11 6 0,000 0,03048747 0,08945471 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03048747 0,08934575 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03048747 0,08923705 ! protein refolding GO:0042026 15 6 0,000 0,03048747 0,08912862 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03048747 0,08902046 ! opsonization GO:0008228 8 6 0,000 0,03048747 0,08891256 ! mating behavior GO:0007617 7 6 0,000 0,03048747 0,08880491 ! neuron remodeling GO:0016322 15 6 0,000 0,03048747 0,08869753 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03048747 0,08859041 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03048747 0,08848354 ! equilibrioception GO:0050957 14 6 0,000 0,03048747 0,08837694 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03048747 0,08827059 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03048747 0,08816449 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03048747 0,08805865 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03048747 0,08795307 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03048747 0,08784773 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03048747 0,08774265 ! toxin metabolic process GO:0009404 11 6 0,000 0,03048747 0,08763782 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03048747 0,08753324 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03048747 0,08742891 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03048747 0,08732483 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03048747 0,087221 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03048747 0,08711741 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03048747 0,08701407 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03048747 0,08691097 ! protein lipoylation GO:0009249 10 6 0,000 0,03048747 0,08680812 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03048747 0,08670551 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03048747 0,08660314 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03048747 0,08650101 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03048747 0,08639913 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03048747 0,08629748 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03048747 0,08619607 ! response to pH GO:0009268 10 6 0,000 0,03048747 0,0860949 ! hyperosmotic response GO:0006972 9 6 0,000 0,03048747 0,08599397 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03048747 0,08589328 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03048747 0,08579282 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03048747 0,08569259 ! urea metabolic process GO:0019627 7 6 0,000 0,03048747 0,0855926 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03048747 0,08549284 ! neutrophil activation GO:0042119 8 6 0,000 0,03048747 0,08539332 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03048747 0,08529402 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03048747 0,08519496 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03048747 0,08509612 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03048747 0,08499752 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03048747 0,08489914 ! neuron apoptosis GO:0051402 9 6 0,000 0,03048747 0,08480099 ! nucleoside salvage GO:0043174 9 6 0,000 0,03048747 0,08470307 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03048747 0,08460537 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03048747 0,0845079 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03048747 0,08441065 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03048747 0,08431363 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03048747 0,08421683 ! carnitine transport GO:0015879 10 6 0,000 0,03048747 0,08412025 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03048747 0,08402389 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03048747 0,08392776 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03048747 0,08383184 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03048747 0,08373614 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03048747 0,08364066 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03048747 0,0835454 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03048747 0,08345035 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03048747 0,08335552 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03048747 0,08326091 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03048747 0,08316651 ! neural nucleus development GO:0048857 14 6 0,000 0,03048747 0,08307232 ! response to UV-C GO:0010225 11 6 0,000 0,03048747 0,08297835 ! astrocyte development GO:0014002 15 6 0,000 0,03048747 0,08288459 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03048747 0,08279104 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03048747 0,0826977 ! interaction with symbiont GO:0051702 13 6 0,000 0,03048747 0,08260457 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03048747 0,08251165 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03048747 0,08241894 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03048747 0,08232644 ! response to copper ion GO:0046688 10 6 0,000 0,03048747 0,08223415 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03048747 0,08214206 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03048747 0,08205018 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03048747 0,0819585 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03048747 0,08186703 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03048747 0,08177576 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03048747 0,0816847 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03048747 0,08159384 ! hair follicle maturation GO:0048820 7 6 0,000 0,03048747 0,08150318 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03048747 0,08141272 ! Schwann cell development GO:0014044 15 6 0,000 0,03048747 0,08132246 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03048747 0,0812324 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03048747 0,08114254 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03048747 0,08105288 ! subpallium development GO:0021544 10 6 0,000 0,03048747 0,08096342 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03048747 0,08087415 ! histone ubiquitination GO:0016574 8 6 0,000 0,03048747 0,08078509 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03048747 0,08069621 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03048747 0,08060754 ! G2 phase GO:0051319 16 6 0,000 0,03048747 0,08051905 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03048747 0,08043077 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03048747 0,08034267 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03048747 0,08025477 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03048747 0,08016706 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03048747 0,08007954 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03048747 0,07999221 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03048747 0,07990507 ! receptor internalization GO:0031623 10 6 0,000 0,03048747 0,07981813 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03048747 0,07973137 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,03048747 0,0796448 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03048747 0,07955841 ! protein destabilization GO:0031648 9 6 0,000 0,03048747 0,07947222 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03048747 0,07938621 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03048747 0,07930039 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03048747 0,07921475 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03048747 0,0791293 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03048747 0,07904403 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03048747 0,07895894 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03048747 0,07887404 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03048747 0,07878932 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03048747 0,07870478 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03048747 0,07862043 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03048747 0,07853625 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03048747 0,07845225 ! catecholamine transport GO:0051937 9 6 0,000 0,03048747 0,07836844 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03048747 0,0782848 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03048747 0,07820134 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03048747 0,07811806 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03048747 0,07803496 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03048747 0,07795203 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03048747 0,07786928 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03048747 0,0777867 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03048747 0,0777043 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03048747 0,07762207 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03162691 0,080438 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03162691 0,08035306 ! cell recognition GO:0008037 85 54 1,000 0,03162691 0,0802683 ! glucose catabolic process GO:0006007 82 55 1,000 0,03271158 0,08293367 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,03271158 0,08284637 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03271158 0,08275926 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03271158 0,08267232 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,03271158 0,08258557 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03381071 0,08527103 ! regulation of DNA replication GO:0006275 101 56 1,000 0,03381071 0,08518174 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03381071 0,08509263 ! muscle fiber development GO:0048747 112 57 1,000 0,03492412 0,08780297 ! lipid modification GO:0030258 97 57 1,000 0,03492412 0,08771132 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03492412 0,08761986 ! tRNA transcription GO:0009304 14 7 0,000 0,03547815 0,08891713 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03547815 0,0888246 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03547815 0,08873227 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03547815 0,08864013 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03547815 0,08854817 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03547815 0,08845642 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03547815 0,08836485 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03547815 0,08827346 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03547815 0,08818227 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03547815 0,08809127 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03547815 0,08800045 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03547815 0,08790983 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03547815 0,08781938 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03547815 0,08772913 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03547815 0,08763906 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03547815 0,08754917 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03547815 0,08745947 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03547815 0,08736995 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03547815 0,08728061 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03547815 0,08719146 ! glycolipid transport GO:0046836 10 7 0,000 0,03547815 0,08710249 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03547815 0,0870137 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03547815 0,08692509 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03547815 0,08683666 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03547815 0,08674842 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03547815 0,08666035 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03547815 0,08657245 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03547815 0,08648474 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03547815 0,08639721 ! pericardium development GO:0060039 14 7 0,000 0,03547815 0,08630985 ! fibril organization GO:0043206 16 7 0,000 0,03547815 0,08622267 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03547815 0,08613566 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03547815 0,08604883 ! lipoprotein transport GO:0042953 14 7 0,000 0,03547815 0,08596218 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03547815 0,08587569 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03547815 0,08578939 ! rhythmic behavior GO:0007622 15 7 0,000 0,03547815 0,08570325 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03547815 0,08561729 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03547815 0,0855315 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03547815 0,08544589 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03547815 0,08536044 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03547815 0,08527517 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03547815 0,08519006 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03547815 0,08510513 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03547815 0,08502036 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03547815 0,08493576 ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03547815 0,08485133 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03547815 0,08476707 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03547815 0,08468298 ! spinal cord patterning GO:0021511 13 7 0,000 0,03547815 0,08459905 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03547815 0,08451529 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03547815 0,08443169 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03547815 0,08434826 ! adrenal gland development GO:0030325 17 7 0,000 0,03547815 0,084265 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03547815 0,08418189 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03547815 0,08409896 ! ovulation GO:0030728 9 7 0,000 0,03547815 0,08401618 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03547815 0,08393357 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03547815 0,08385112 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03547815 0,08376883 ! microtubule nucleation GO:0007020 20 7 0,000 0,03547815 0,08368671 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03547815 0,08360474 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03547815 0,08352294 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03547815 0,08344129 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03547815 0,08335981 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03547815 0,08327848 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03547815 0,08319731 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03547815 0,0831163 ! galactose metabolic process GO:0006012 13 7 0,000 0,03547815 0,08303545 ! vesicle fusion GO:0006906 17 7 0,000 0,03547815 0,08295475 ! response to dietary excess GO:0002021 8 7 0,000 0,03547815 0,08287421 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03547815 0,08279383 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03547815 0,08271361 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,03547815 0,08263353 ! organ growth GO:0035265 15 7 0,000 0,03547815 0,08255362 ! purine salvage GO:0043101 10 7 0,000 0,03547815 0,08247386 ! nucleoside transport GO:0015858 8 7 0,000 0,03547815 0,08239425 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03547815 0,08231479 ! parturition GO:0007567 14 7 0,000 0,03547815 0,08223549 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03547815 0,08215634 ! rRNA modification GO:0000154 14 7 0,000 0,03547815 0,08207735 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03547815 0,0819985 ! spindle checkpoint GO:0031577 15 7 0,000 0,03547815 0,08191981 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03547815 0,08184127 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03547815 0,08176287 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03547815 0,08168463 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03547815 0,08160654 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03547815 0,0815286 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03547815 0,0814508 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03547815 0,08137316 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03547815 0,08129566 ! fibrinolysis GO:0042730 10 7 0,000 0,03547815 0,08121831 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03547815 0,0811411 ! eating behavior GO:0042755 7 7 0,000 0,03547815 0,08106405 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03547815 0,08098714 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03547815 0,08091037 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03547815 0,08083375 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03547815 0,08075728 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03547815 0,08068095 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03547815 0,08060476 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03547815 0,08052872 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03547815 0,08045282 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03547815 0,08037706 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03547815 0,08030145 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03547815 0,08022598 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03547815 0,08015065 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03547815 0,08007546 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03547815 0,08000041 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03547815 0,07992551 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03547815 0,07985074 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03547815 0,07977611 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03547815 0,07970163 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03547815 0,07962728 ! transcription termination GO:0006353 13 7 0,000 0,03547815 0,07955307 ! response to tumor cell GO:0002347 13 7 0,000 0,03547815 0,07947899 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03547815 0,07940506 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03547815 0,07933126 ! anaphase GO:0051322 17 7 0,000 0,03547815 0,0792576 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03547815 0,07918408 ! axonal fasciculation GO:0007413 18 7 0,000 0,03547815 0,0791107 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03547815 0,07903744 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03547815 0,07896433 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03547815 0,07889135 ! diuresis GO:0030146 12 7 0,000 0,03547815 0,0788185 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03547815 0,07874579 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03547815 0,07867322 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03547815 0,07860077 ! antibiotic transport GO:0042891 9 7 0,000 0,03547815 0,07852846 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03547815 0,07845629 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03547815 0,07838424 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03547815 0,07831233 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03547815 0,07824055 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03547815 0,0781689 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03547815 0,07809738 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03547815 0,078026 ! lymph node development GO:0048535 10 7 0,000 0,03547815 0,07795474 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03547815 0,07788361 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03547815 0,07781262 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03547815 0,07774175 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03547815 0,07767101 ! adult feeding behavior GO:0008343 9 7 0,000 0,03547815 0,0776004 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03547815 0,07752992 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03547815 0,07745956 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03547815 0,07738934 ! muscle adaptation GO:0043500 14 7 0,000 0,03547815 0,07731924 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03547815 0,07724927 ! retina homeostasis GO:0001895 12 7 0,000 0,03547815 0,07717942 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03547815 0,0771097 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03547815 0,07704011 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03547815 0,07697064 ! protein prenylation GO:0018342 18 7 0,000 0,03547815 0,0769013 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03547815 0,07683208 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03547815 0,07676299 ! regulation of endocytosis GO:0030100 91 58 1,000 0,03605166 0,07793377 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03605166 0,07786381 ! positive regulation of secretion GO:0051047 95 59 1,000 0,03719313 0,0802571 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,03719313 0,08018519 ! camera-type eye development GO:0043010 116 60 1,000 0,03834837 0,08260178 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,03834837 0,0825279 ! kidney development GO:0001822 122 60 1,000 0,03834837 0,08245414 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04044331 0,0868809 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04044331 0,0868034 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04044331 0,08672603 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04044331 0,08664881 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04044331 0,08657172 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04044331 0,08649476 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04044331 0,08641795 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04044331 0,08634127 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04044331 0,08626472 ! meiotic prophase I GO:0007128 13 8 0,000 0,04044331 0,08618832 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04044331 0,08611204 ! oligopeptide transport GO:0006857 15 8 0,000 0,04044331 0,08603591 ! UTP metabolic process GO:0046051 8 8 0,000 0,04044331 0,0859599 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04044331 0,08588403 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04044331 0,0858083 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04044331 0,0857327 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04044331 0,08565723 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04044331 0,08558189 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04044331 0,08550669 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04044331 0,08543161 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04044331 0,08535667 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04044331 0,08528187 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04044331 0,08520719 ! reflex GO:0060004 16 8 0,000 0,04044331 0,08513264 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04044331 0,08505822 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04044331 0,08498394 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04044331 0,08490978 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04044331 0,08483575 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04044331 0,08476185 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04044331 0,08468808 ! pigment granule organization GO:0048753 16 8 0,000 0,04044331 0,08461444 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04044331 0,08454093 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04044331 0,08446754 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04044331 0,08439428 ! histidine metabolic process GO:0006547 16 8 0,000 0,04044331 0,08432115 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04044331 0,08424815 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04044331 0,08417527 ! glycine catabolic process GO:0006546 13 8 0,000 0,04044331 0,08410251 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04044331 0,08402989 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04044331 0,08395738 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04044331 0,08388501 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04044331 0,08381276 ! melanin metabolic process GO:0006582 15 8 0,000 0,04044331 0,08374063 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04044331 0,08366862 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04044331 0,08359674 ! macrophage activation GO:0042116 12 8 0,000 0,04044331 0,08352499 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04044331 0,08345335 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04044331 0,08338184 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04044331 0,08331045 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04044331 0,08323919 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04044331 0,08316804 ! osteoblast development GO:0002076 16 8 0,000 0,04044331 0,08309702 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04044331 0,08302612 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04044331 0,08295534 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04044331 0,08288468 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04044331 0,08281414 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04044331 0,08274372 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04044331 0,08267341 ! response to UV-B GO:0010224 16 8 0,000 0,04044331 0,08260323 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04044331 0,08253317 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04044331 0,08246323 ! intermediate filament organization GO:0045109 12 8 0,000 0,04044331 0,0823934 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04044331 0,0823237 ! cellular extravasation GO:0045123 12 8 0,000 0,04044331 0,08225411 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04044331 0,08218464 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04044331 0,08211528 ! response to antibiotic GO:0046677 11 8 0,000 0,04044331 0,08204604 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04044331 0,08197692 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04044331 0,08190792 ! DNA topological change GO:0006265 12 8 0,000 0,04044331 0,08183903 ! response to tropane GO:0014073 15 8 0,000 0,04044331 0,08177026 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04044331 0,0817016 ! melanosome transport GO:0032402 13 8 0,000 0,04044331 0,08163306 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04044331 0,08156463 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04044331 0,08149632 ! mast cell activation GO:0045576 14 8 0,000 0,04044331 0,08142812 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04044331 0,08136004 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04044331 0,08129207 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04044331 0,08122421 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04044331 0,08115647 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04044331 0,08108884 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04044331 0,08102132 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04044331 0,08095392 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04044331 0,08088662 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04044331 0,08081944 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04044331 0,08075237 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04044331 0,08068541 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04044331 0,08061857 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04044331 0,08055183 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04044331 0,0804852 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04044331 0,08041869 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04044331 0,08035228 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04044331 0,08028598 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04044331 0,08021979 ! hormone catabolic process GO:0042447 17 8 0,000 0,04044331 0,08015371 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04044331 0,08008774 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04044331 0,08002188 ! ATP catabolic process GO:0006200 11 8 0,000 0,04044331 0,07995613 ! blastocyst growth GO:0001832 19 8 0,000 0,04044331 0,07989048 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04044331 0,07982495 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04044331 0,07975952 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04044331 0,07969419 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04044331 0,07962898 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04044331 0,07956387 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04044331 0,07949886 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04044331 0,07943397 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04044331 0,07936918 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04044331 0,07930449 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04044331 0,07923991 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04044331 0,07917543 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04044331 0,07911106 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04044331 0,0790468 ! ear development GO:0043583 103 62 1,000 0,04069949 0,07948294 ! viral reproductive process GO:0022415 126 62 1,000 0,04069949 0,07941848 ! gonad development GO:0008406 98 62 1,000 0,04069949 0,07935412 ! regulation of mitosis GO:0007088 105 63 1,000 0,04189503 0,08161899 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,04189503 0,08155295 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,04310367 0,08383786 GO:0048609|reproductive process in a multicellular organism, ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,04432524 0,08614421 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,04432524 0,08607468 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,04432524 0,08600527 ! regulation of developmental growth GO:0048638 15 9 0,000 0,04538307 0,08798685 ! axon extension GO:0048675 15 9 0,000 0,04538307 0,087916 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04538307 0,08784527 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04538307 0,08777466 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04538307 0,08770416 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04538307 0,08763377 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04538307 0,08756349 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04538307 0,08749333 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04538307 0,08742328 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04538307 0,08735334 ! phosphate transport GO:0006817 19 9 0,000 0,04538307 0,08728351 ! reproductive behavior GO:0019098 19 9 0,000 0,04538307 0,0872138 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04538307 0,08714419 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04538307 0,0870747 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04538307 0,08700532 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04538307 0,08693605 ! GTP metabolic process GO:0046039 9 9 0,000 0,04538307 0,08686689 ! RNA methylation GO:0001510 15 9 0,000 0,04538307 0,08679783 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04538307 0,08672889 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04538307 0,08666006 ! artery development GO:0060840 24 9 0,000 0,04538307 0,08659134 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04538307 0,08652272 ! regulation of glycolysis GO:0006110 21 9 0,000 0,04538307 0,08645422 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04538307 0,08638582 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04538307 0,08631753 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04538307 0,08624935 ! chemosensory behavior GO:0007635 20 9 0,000 0,04538307 0,08618128 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04538307 0,08611331 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04538307 0,08604545 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04538307 0,0859777 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04538307 0,08591005 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04538307 0,08584251 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04538307 0,08577508 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04538307 0,08570775 ! protein targeting to ER GO:0045047 22 9 0,000 0,04538307 0,08564053 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04538307 0,08557341 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04538307 0,0855064 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04538307 0,0854395 ! endosome organization GO:0007032 17 9 0,000 0,04538307 0,08537269 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04538307 0,085306 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04538307 0,0852394 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04538307 0,08517291 ! mannose metabolic process GO:0006013 13 9 0,000 0,04538307 0,08510653 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04538307 0,08504025 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04538307 0,08497407 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04538307 0,08490799 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04538307 0,08484202 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04538307 0,08477615 ! ruffle organization GO:0031529 15 9 0,000 0,04538307 0,08471038 ! retinol metabolic process GO:0042572 18 9 0,000 0,04538307 0,08464471 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04538307 0,08457914 ! behavioral fear response GO:0001662 22 9 0,000 0,04538307 0,08451368 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04538307 0,08444832 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04538307 0,08438306 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04538307 0,0843179 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,04538307 0,08425284 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04538307 0,08418788 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04538307 0,08412302 ! segment specification GO:0007379 13 9 0,000 0,04538307 0,08405826 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04538307 0,0839936 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04538307 0,08392904 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04538307 0,08386457 ! response to amine stimulus GO:0014075 13 9 0,000 0,04538307 0,08380021 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04538307 0,08373595 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04538307 0,08367178 ! erythrocyte development GO:0048821 15 9 0,000 0,04538307 0,08360771 ! gas homeostasis GO:0033483 16 9 0,000 0,04538307 0,08354375 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04538307 0,08347987 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04538307 0,0834161 ! renal water homeostasis GO:0003091 14 9 0,000 0,04538307 0,08335242 ! postreplication repair GO:0006301 22 9 0,000 0,04538307 0,08328884 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04538307 0,08322536 ! icosanoid secretion GO:0032309 15 9 0,000 0,04538307 0,08316198 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04538307 0,08309869 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04538307 0,08303549 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04538307 0,0829724 ! regulation of cell division GO:0051302 15 9 0,000 0,04538307 0,0829094 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04538307 0,08284649 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04538307 0,08278368 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04538307 0,08272097 ! sterol catabolic process GO:0016127 11 9 0,000 0,04538307 0,08265835 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04538307 0,08259582 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04538307 0,08253339 ! S phase GO:0051320 9 9 0,000 0,04538307 0,08247105 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04538307 0,08240881 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04538307 0,08234666 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04538307 0,08228461 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04538307 0,08222265 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04538307 0,08216078 ! purine base metabolic process GO:0006144 21 9 0,000 0,04538307 0,082099 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04538307 0,08203732 ! pigment granule transport GO:0051904 17 9 0,000 0,04538307 0,08197573 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04538307 0,08191424 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04538307 0,08185283 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04538307 0,08179152 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04538307 0,0817303 ! mitochondrion localization GO:0051646 15 9 0,000 0,04538307 0,08166917 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,04555959 0,08192553 ! developmental maturation GO:0021700 116 66 1,000 0,04555959 0,08186435 ! chromosome segregation GO:0007059 113 67 1,000 0,04680654 0,08404219 ! hexose catabolic process GO:0019320 104 67 1,000 0,04680654 0,08397951 ! adaptive immune response GO:0002250 119 67 1,000 0,04680654 0,08391694 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,04680654 0,08385445 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,04806594 0,08604661 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,04806594 0,08598263 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04806594 0,08591875 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,04806594 0,08585497 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,04933763 0,08806107 ! antigen processing and presentation GO:0019882 104 69 1,000 0,04933763 0,08799579 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05029757 0,08964145 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05029757 0,08957509 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05029757 0,08950884 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05029757 0,08944268 ! synapsis GO:0007129 13 10 0,000 0,05029757 0,08937663 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05029757 0,08931067 ! N-glycan processing GO:0006491 20 10 0,000 0,05029757 0,0892448 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05029757 0,08917904 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05029757 0,08911337 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05029757 0,08904779 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05029757 0,08898232 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05029757 0,08891694 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05029757 0,08885165 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05029757 0,08878646 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05029757 0,08872137 ! androgen metabolic process GO:0008209 17 10 0,000 0,05029757 0,08865637 ! phospholipid efflux GO:0033700 16 10 0,000 0,05029757 0,08859147 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05029757 0,08852667 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05029757 0,08846195 ! pathogenesis GO:0009405 13 10 0,000 0,05029757 0,08839733 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05029757 0,08833281 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05029757 0,08826838 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05029757 0,08820405 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05029757 0,0881398 ! endoderm development GO:0007492 16 10 0,000 0,05029757 0,08807566 ! arginine catabolic process GO:0006527 13 10 0,000 0,05029757 0,0880116 ! proline metabolic process GO:0006560 13 10 0,000 0,05029757 0,08794764 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05029757 0,08788377 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05029757 0,08781999 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05029757 0,08775631 ! V(D)J recombination GO:0033151 28 10 0,000 0,05029757 0,08769272 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05029757 0,08762922 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05029757 0,08756581 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05029757 0,0875025 ! B cell proliferation GO:0042100 18 10 0,000 0,05029757 0,08743927 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05029757 0,08737614 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05029757 0,0873131 ! multicellular organism growth GO:0035264 18 10 0,000 0,05029757 0,08725015 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05029757 0,08718728 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05029757 0,08712452 ! epithelial cell development GO:0002064 20 10 0,000 0,05029757 0,08706184 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05029757 0,08699925 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05029757 0,08693675 ! macroautophagy GO:0016236 17 10 0,000 0,05029757 0,08687434 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05029757 0,08681202 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05029757 0,08674979 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05029757 0,08668764 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05029757 0,08662559 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05029757 0,08656363 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05029757 0,08650175 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05029757 0,08643997 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05029757 0,08637827 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05029757 0,08631666 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05029757 0,08625513 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05029757 0,0861937 ! response to dsRNA GO:0043331 20 10 0,000 0,05029757 0,08613235 ! DNA ligation GO:0006266 19 10 0,000 0,05029757 0,08607109 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05029757 0,08600992 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05029757 0,08594883 ! melanosome localization GO:0032400 16 10 0,000 0,05029757 0,08588783 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05029757 0,08582692 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05029757 0,08576609 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05029757 0,08570535 ! mRNA cleavage GO:0006379 17 10 0,000 0,05029757 0,08564469 ! protein sumoylation GO:0016925 15 10 0,000 0,05029757 0,08558412 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05029757 0,08552364 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05029757 0,08546324 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05029757 0,08540293 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05029757 0,0853427 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05029757 0,08528256 ! prophase GO:0051324 15 10 0,000 0,05029757 0,0852225 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05029757 0,08516253 ! apical protein localization GO:0045176 15 10 0,000 0,05029757 0,08510264 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05029757 0,08504283 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,05029757 0,08498311 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05029757 0,08492347 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05029757 0,08486392 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05029757 0,08480445 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05029757 0,08474506 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05029757 0,08468576 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05029757 0,08462654 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05029757 0,0845674 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05029757 0,08450835 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05029757 0,08444937 ! oocyte development GO:0048599 17 10 0,000 0,05029757 0,08439048 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05029757 0,08433167 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05029757 0,08427295 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05029757 0,0842143 ! activation of innate immune response GO:0002218 12 10 0,000 0,05029757 0,08415574 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05029757 0,08409726 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05029757 0,08403886 ! response to nicotine GO:0035094 20 10 0,000 0,05029757 0,08398054 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05029757 0,0839223 ! appendage morphogenesis GO:0035107 135 70 1,000 0,05062144 0,08440415 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,05191724 0,08650476 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,05191724 0,0864449 ! acute inflammatory response GO:0002526 113 72 1,000 0,05322485 0,08856085 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,05322485 0,08849965 ! carbohydrate transport GO:0008643 110 72 1,000 0,05322485 0,08843853 ! learning or memory GO:0007611 147 73 1,000 0,05454413 0,09056809 ! axon guidance GO:0007411 139 73 1,000 0,05454413 0,09050563 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05518693 0,09150913 ! respiratory burst GO:0045730 17 11 0,000 0,05518693 0,09144611 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05518693 0,09138317 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05518693 0,09132032 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05518693 0,09125756 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,05518693 0,09119488 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05518693 0,09113229 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05518693 0,09106978 ! response to pain GO:0048265 24 11 0,000 0,05518693 0,09100736 ! bone resorption GO:0045453 16 11 0,000 0,05518693 0,09094503 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05518693 0,09088278 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05518693 0,09082062 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05518693 0,09075854 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05518693 0,09069655 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05518693 0,09063464 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05518693 0,09057281 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05518693 0,09051107 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05518693 0,09044942 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05518693 0,09038785 ! lipid digestion GO:0044241 18 11 0,000 0,05518693 0,09032636 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05518693 0,09026495 ! UV protection GO:0009650 19 11 0,000 0,05518693 0,09020363 ! adult heart development GO:0007512 14 11 0,000 0,05518693 0,09014239 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05518693 0,09008124 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05518693 0,09002017 ! temperature homeostasis GO:0001659 17 11 0,000 0,05518693 0,08995918 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05518693 0,08989827 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05518693 0,08983745 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05518693 0,0897767 ! regulation of organ growth GO:0046620 13 11 0,000 0,05518693 0,08971604 ! pigment granule localization GO:0051875 20 11 0,000 0,05518693 0,08965547 ! vasoconstriction GO:0042310 18 11 0,000 0,05518693 0,08959497 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05518693 0,08953455 ! embryonic axis specification GO:0000578 18 11 0,000 0,05518693 0,08947422 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05518693 0,08941397 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05518693 0,0893538 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05518693 0,08929371 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05518693 0,0892337 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05518693 0,08917377 ! zymogen activation GO:0031638 15 11 0,000 0,05518693 0,08911392 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05518693 0,08905415 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05518693 0,08899447 ! nucleosome positioning GO:0016584 15 11 0,000 0,05518693 0,08893486 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05518693 0,08887533 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05518693 0,08881588 ! acid secretion GO:0046717 18 11 0,000 0,05518693 0,08875651 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05518693 0,08869722 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05518693 0,08863801 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05518693 0,08857888 ! oocyte differentiation GO:0009994 18 11 0,000 0,05518693 0,08851983 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05518693 0,08846086 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05518693 0,08840196 ! cholesterol efflux GO:0033344 19 11 0,000 0,05518693 0,08834314 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05518693 0,0882844 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05518693 0,08822574 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05518693 0,08816716 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05518693 0,08810866 ! embryonic gut development GO:0048566 15 11 0,000 0,05518693 0,08805023 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05518693 0,08799188 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05518693 0,08793361 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05518693 0,08787541 ! defense response to fungus GO:0050832 13 11 0,000 0,05518693 0,08781729 ! developmental induction GO:0031128 19 11 0,000 0,05518693 0,08775925 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05518693 0,08770128 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05518693 0,0876434 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05518693 0,08758558 ! regulation of embryonic development GO:0045995 27 11 0,000 0,05518693 0,08752785 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05518693 0,08747019 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,05587491 0,08850233 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,05721706 0,09056859 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,05721706 0,09050904 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,05721706 0,09044957 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,05857042 0,09252819 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,05857042 0,09246747 ! defense response to bacterium GO:0042742 89 76 1,000 0,05857042 0,09240684 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,05857042 0,09234628 ! regulation of catabolic process GO:0009894 161 76 1,000 0,05857042 0,09228581 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06005127 0,09455717 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06005127 0,09449533 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,06005127 0,09443357 ! virus-host interaction GO:0019048 29 12 0,000 0,06005127 0,09437189 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06005127 0,09431029 ! mating GO:0007618 17 12 0,000 0,06005127 0,09424877 ! protein complex disassembly GO:0043241 27 12 0,000 0,06005127 0,09418733 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,06005127 0,09412597 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06005127 0,09406469 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06005127 0,09400349 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06005127 0,09394237 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06005127 0,09388133 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06005127 0,09382037 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06005127 0,09375948 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06005127 0,09369868 ! drug transport GO:0015893 16 12 0,000 0,06005127 0,09363795 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06005127 0,09357731 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06005127 0,09351674 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06005127 0,09345625 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06005127 0,09339584 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06005127 0,09333551 ! forebrain cell migration GO:0021885 21 12 0,000 0,06005127 0,09327525 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06005127 0,09321507 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06005127 0,09315497 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06005127 0,09309495 ! fear response GO:0042596 26 12 0,000 0,06005127 0,09303501 ! monoamine transport GO:0015844 18 12 0,000 0,06005127 0,09297514 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06005127 0,09291535 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06005127 0,09285563 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06005127 0,09279599 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06005127 0,09273643 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06005127 0,09267695 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06005127 0,09261754 ! protein homotetramerization GO:0051289 21 12 0,000 0,06005127 0,09255821 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06005127 0,09249895 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06005127 0,09243977 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06005127 0,09238067 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06005127 0,09232164 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06005127 0,09226268 ! cranial nerve development GO:0021545 20 12 0,000 0,06005127 0,09220381 ! fucose catabolic process GO:0019317 22 12 0,000 0,06005127 0,092145 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06005127 0,09208627 ! histone methylation GO:0016571 26 12 0,000 0,06005127 0,09202762 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06005127 0,09196904 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06005127 0,09191054 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06005127 0,09185211 ! T cell homeostasis GO:0043029 25 12 0,000 0,06005127 0,09179375 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06005127 0,09173547 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06005127 0,09167726 ! spleen development GO:0048536 22 12 0,000 0,06005127 0,09161913 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06005127 0,09156107 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06005127 0,09150308 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06005127 0,09144517 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06005127 0,09138733 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06005127 0,09132956 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06005127 0,09127187 ! response to cold GO:0009409 17 12 0,000 0,06005127 0,09121424 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06005127 0,0911567 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06005127 0,09109922 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,06131017 0,09295038 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,06269626 0,09499194 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,06409298 0,09704701 ! muscle cell differentiation GO:0042692 159 80 1,000 0,06409298 0,09698597 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,06409298 0,09692502 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06489074 0,09806979 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06489074 0,09800823 ! peroxisomal transport GO:0043574 24 13 0,000 0,06489074 0,09794675 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06489074 0,09788534 ! lipid localization GO:0010876 28 13 0,000 0,06489074 0,09782401 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06489074 0,09776275 ! organelle fusion GO:0048284 32 13 0,000 0,06489074 0,09770157 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06489074 0,09764047 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06489074 0,09757945 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06489074 0,0975185 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06489074 0,09745762 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06489074 0,09739683 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06489074 0,09733611 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06489074 0,09727546 ! methionine metabolic process GO:0006555 27 13 0,000 0,06489074 0,09721489 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06489074 0,0971544 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06489074 0,09709398 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06489074 0,09703363 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06489074 0,09697336 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06489074 0,09691317 ! response to X-ray GO:0010165 25 13 0,000 0,06489074 0,09685305 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06489074 0,096793 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,06489074 0,09673303 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06489074 0,09667313 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06489074 0,09661331 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06489074 0,09655356 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06489074 0,09649389 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06489074 0,09643429 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06489074 0,09637476 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06489074 0,09631531 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06489074 0,09625593 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06489074 0,09619662 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06489074 0,09613738 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06489074 0,09607822 ! ribosome assembly GO:0042255 17 13 0,000 0,06489074 0,09601913 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06489074 0,09596012 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06489074 0,09590117 ! chromatin silencing GO:0006342 26 13 0,000 0,06489074 0,0958423 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06489074 0,0957835 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06489074 0,09572478 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06489074 0,09566612 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06489074 0,09560754 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06489074 0,09554903 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06489074 0,09549059 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06489074 0,09543222 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06489074 0,09537392 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06489074 0,0953157 ! insulin secretion GO:0030073 23 13 0,000 0,06489074 0,09525754 ! actin filament polymerization GO:0030041 24 13 0,000 0,06489074 0,09519946 ! acrosome reaction GO:0007340 18 13 0,000 0,06489074 0,09514145 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,06691769 0,09805357 ! response to drug GO:0042493 143 82 1,000 0,06691769 0,09799389 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,06691769 0,09793428 ! regulation of lyase activity GO:0051339 160 83 1,000 0,0683454 0,09996294 ! rRNA transcription GO:0009303 25 14 0,000 0,06970544 0,10189022 ! lactation GO:0007595 26 14 0,000 0,06970544 0,10182835 ! reproductive cellular process GO:0048610 20 14 0,000 0,06970544 0,10176656 ! tRNA modification GO:0006400 20 14 0,000 0,06970544 0,10170485 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06970544 0,10164321 ! water transport GO:0006833 21 14 0,000 0,06970544 0,10158165 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06970544 0,10152016 ! non-recombinational repair GO:0000726 25 14 0,000 0,06970544 0,10145874 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06970544 0,1013974 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06970544 0,10133613 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06970544 0,10127494 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06970544 0,10121382 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06970544 0,10115277 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06970544 0,1010918 ! palate development GO:0060021 31 14 0,000 0,06970544 0,1010309 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06970544 0,10097008 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06970544 0,10090932 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06970544 0,10084865 ! arginine metabolic process GO:0006525 17 14 0,000 0,06970544 0,10078804 ! regulation of heart rate GO:0002027 24 14 0,000 0,06970544 0,10072751 ! organic alcohol transport GO:0015850 29 14 0,000 0,06970544 0,10066705 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06970544 0,10060666 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06970544 0,10054634 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06970544 0,1004861 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06970544 0,10042593 ! L-amino acid transport GO:0015807 30 14 0,000 0,06970544 0,10036583 ! bone mineralization GO:0030282 17 14 0,000 0,06970544 0,1003058 ! stem cell development GO:0048864 43 14 0,000 0,06970544 0,10024584 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06970544 0,10018596 ! cerebellum development GO:0021549 21 14 0,000 0,06970544 0,10012615 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06970544 0,10006641 ! response to gamma radiation GO:0010332 28 14 0,000 0,06970544 0,10000674 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06970544 0,09994714 ! cofactor transport GO:0051181 26 14 0,000 0,06970544 0,09988761 ! NADP metabolic process GO:0006739 24 14 0,000 0,06970544 0,09982815 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06970544 0,09976877 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06970544 0,09970945 ! intestinal absorption GO:0050892 25 14 0,000 0,06970544 0,09965021 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06970544 0,09959103 ! oxygen transport GO:0015671 21 14 0,000 0,06970544 0,09953193 ! male genitalia development GO:0030539 24 14 0,000 0,06970544 0,09947289 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06970544 0,09941393 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,06978316 0,09946581 ! nucleosome assembly GO:0006334 122 85 1,000 0,07123083 0,10146915 ! chromatin assembly GO:0031497 124 86 1,000 0,07268828 0,10348402 ! alcohol catabolic process GO:0046164 130 86 1,000 0,07268828 0,10342282 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,07415535 0,10544786 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07449552 0,105869 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07449552 0,10580651 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07449552 0,10574408 ! superoxide anion generation GO:0042554 20 15 0,000 0,07449552 0,10568173 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07449552 0,10561946 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07449552 0,10555726 ! copper ion transport GO:0006825 20 15 0,000 0,07449552 0,10549513 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07449552 0,10543307 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07449552 0,10537109 ! sulfate transport GO:0008272 23 15 0,000 0,07449552 0,10530918 ! response to cAMP GO:0051591 22 15 0,000 0,07449552 0,10524734 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07449552 0,10518558 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07449552 0,10512388 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07449552 0,10506226 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07449552 0,10500071 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07449552 0,10493924 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07449552 0,10487784 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07449552 0,1048165 ! pituitary gland development GO:0021983 29 15 0,000 0,07449552 0,10475524 ! vesicle coating GO:0006901 33 15 0,000 0,07449552 0,10469405 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07449552 0,10463294 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07449552 0,10457189 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07449552 0,10451092 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07449552 0,10445001 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,07449552 0,10438918 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07449552 0,10432842 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07449552 0,10426773 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07449552 0,1042071 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07449552 0,10414655 ! histone deacetylation GO:0016575 20 15 0,000 0,07449552 0,10408607 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07449552 0,10402566 ! tissue regeneration GO:0042246 26 15 0,000 0,07449552 0,10396532 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07449552 0,10390506 ! water homeostasis GO:0030104 27 15 0,000 0,07449552 0,10384486 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07449552 0,10378473 ! muscle maintenance GO:0046716 26 15 0,000 0,07449552 0,10372466 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07449552 0,10366467 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07449552 0,10360475 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07449552 0,1035449 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07449552 0,10348512 ! cell killing GO:0001906 29 15 0,000 0,07449552 0,1034254 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07449552 0,10336576 ! detection of bacterium GO:0016045 18 15 0,000 0,07449552 0,10330618 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07449552 0,10324667 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07449552 0,10318723 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07449552 0,10312786 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07449552 0,10306856 ! peptide hormone processing GO:0016486 23 15 0,000 0,07449552 0,10300932 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,07861303 0,1086404 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,07861303 0,10857804 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07926109 0,10941032 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07926109 0,10934758 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07926109 0,10928492 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07926109 0,10922233 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07926109 0,10915981 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,07926109 0,10909736 ! bone remodeling GO:0046849 27 16 0,000 0,07926109 0,10903498 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07926109 0,10897268 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07926109 0,10891044 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07926109 0,10884828 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07926109 0,10878618 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07926109 0,10872416 ! startle response GO:0001964 28 16 0,000 0,07926109 0,10866221 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07926109 0,10860033 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,07926109 0,10853852 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07926109 0,10847678 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07926109 0,10841511 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07926109 0,10835351 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07926109 0,10829198 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07926109 0,10823052 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07926109 0,10816913 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07926109 0,10810781 ! response to osmotic stress GO:0006970 25 16 0,000 0,07926109 0,10804656 ! lysosomal transport GO:0007041 26 16 0,000 0,07926109 0,10798538 ! fructose metabolic process GO:0006000 25 16 0,000 0,07926109 0,10792427 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07926109 0,10786323 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07926109 0,10780225 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07926109 0,10774135 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07926109 0,10768051 ! axon cargo transport GO:0008088 43 16 0,000 0,07926109 0,10761974 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07926109 0,10755904 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07926109 0,10749841 ! DNA replication initiation GO:0006270 27 16 0,000 0,07926109 0,10743785 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07926109 0,10737735 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07926109 0,10731693 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07926109 0,10725657 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07926109 0,10719628 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07926109 0,10713606 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07926109 0,1070759 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07926109 0,10701581 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07926109 0,10695579 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07926109 0,10689584 ! regulation of defense response GO:0031347 149 92 1,000 0,08163051 0,1100297 ! nucleosome organization GO:0034728 138 92 1,000 0,08163051 0,10996809 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,08315257 0,11195584 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,08315257 0,11189322 ! regulation of membrane potential GO:0042391 164 93 1,000 0,08315257 0,11183068 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08400228 0,11291033 ! metencephalon development GO:0022037 30 17 0,000 0,08400228 0,11284728 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08400228 0,11278431 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08400228 0,11272141 ! endothelial cell migration GO:0043542 28 17 0,000 0,08400228 0,11265857 ! inositol metabolic process GO:0006020 28 17 0,000 0,08400228 0,11259581 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08400228 0,11253312 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08400228 0,1124705 ! glial cell development GO:0021782 27 17 0,000 0,08400228 0,11240794 ! limbic system development GO:0021761 36 17 0,000 0,08400228 0,11234546 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08400228 0,11228305 ! adult walking behavior GO:0007628 33 17 0,000 0,08400228 0,1122207 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08400228 0,11215843 ! heart looping GO:0001947 30 17 0,000 0,08400228 0,11209622 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08400228 0,11203408 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08400228 0,11197201 ! myoblast differentiation GO:0045445 45 17 0,000 0,08400228 0,11191001 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,08400228 0,11184808 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08400228 0,11178622 ! glycine metabolic process GO:0006544 28 17 0,000 0,08400228 0,11172442 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08400228 0,1116627 ! NAD metabolic process GO:0019674 29 17 0,000 0,08400228 0,11160104 ! membrane budding GO:0006900 37 17 0,000 0,08400228 0,11153945 ! DNA integration GO:0015074 29 17 0,000 0,08400228 0,11147793 ! regulation of protein binding GO:0043393 33 17 0,000 0,08400228 0,11141647 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08400228 0,11135509 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08400228 0,11129377 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08400228 0,11123252 ! genitalia development GO:0048806 30 17 0,000 0,08400228 0,11117133 ! neural crest cell migration GO:0001755 37 17 0,000 0,08400228 0,11111022 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,08400228 0,11104917 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08400228 0,11098818 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08400228 0,11092727 ! steroid catabolic process GO:0006706 31 17 0,000 0,08400228 0,11086642 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08400228 0,11080564 ! gas transport GO:0015669 25 17 0,000 0,08400228 0,11074492 ! organic cation transport GO:0015695 31 17 0,000 0,08400228 0,11068427 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08400228 0,11062369 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08400228 0,11056317 ! female pregnancy GO:0007565 164 94 1,000 0,08468333 0,11139863 ! positive regulation of immune response GO:0050778 156 96 1,000 0,08777045 0,11539656 ! detection of stimulus GO:0051606 151 96 1,000 0,08777045 0,11533353 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08871921 0,11651661 ! neuron maturation GO:0042551 42 18 0,000 0,08871921 0,11645304 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08871921 0,11638954 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08871921 0,11632611 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08871921 0,11626276 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08871921 0,11619947 ! memory GO:0007613 31 18 0,000 0,08871921 0,11613625 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08871921 0,11607309 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08871921 0,11601001 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08871921 0,115947 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08871921 0,11588405 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08871921 0,11582117 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08871921 0,11575836 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08871921 0,11569562 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08871921 0,11563295 ! response to retinoic acid GO:0032526 26 18 0,000 0,08871921 0,11557034 ! response to fungus GO:0009620 21 18 0,000 0,08871921 0,1155078 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08871921 0,11544533 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08871921 0,11538293 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08871921 0,11532059 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08871921 0,11525833 ! vitamin transport GO:0051180 27 18 0,000 0,08871921 0,11519613 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08871921 0,11513399 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08871921 0,11507193 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08871921 0,11500993 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,08871921 0,11494799 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08871921 0,11488613 ! nerve development GO:0021675 28 18 0,000 0,08871921 0,11482433 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08871921 0,11476259 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,09246322 0,11954138 ! protein secretion GO:0009306 39 19 0,000 0,09341201 0,12070316 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09341201 0,12063837 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09341201 0,12057365 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09341201 0,120509 ! skin development GO:0043588 36 19 0,000 0,09341201 0,12044442 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09341201 0,12037991 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09341201 0,12031547 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09341201 0,12025109 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09341201 0,12018679 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09341201 0,12012255 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09341201 0,12005838 ! cerebral cortex development GO:0021987 36 19 0,000 0,09341201 0,11999428 ! pigmentation during development GO:0048066 41 19 0,000 0,09341201 0,11993025 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09341201 0,11986629 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09341201 0,11980239 ! heme metabolic process GO:0042168 36 19 0,000 0,09341201 0,11973857 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09341201 0,11967481 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09341201 0,11961112 ! heart process GO:0003015 30 19 0,000 0,09341201 0,1195475 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09341201 0,11948394 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09341201 0,11942045 ! visual learning GO:0008542 36 19 0,000 0,09341201 0,11935703 ! cellular pigmentation GO:0033059 36 19 0,000 0,09341201 0,11929368 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09341201 0,11923039 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09341201 0,11916718 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09341201 0,11910402 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09341201 0,11904094 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09341201 0,11897792 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09341201 0,11891497 ! cilium assembly GO:0042384 37 19 0,000 0,09341201 0,11885208 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0980808 0,12472642 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0980808 0,12466054 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0980808 0,12459472 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0980808 0,12452897 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0980808 0,12446329 ! response to vitamin GO:0033273 31 20 0,000 0,0980808 0,12439768 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0980808 0,12433214 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,0980808 0,12426666 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0980808 0,12420126 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0980808 0,12413592 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0980808 0,12407066 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0980808 0,12400546 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0980808 0,12394033 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0980808 0,12387527 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0980808 0,12381028 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0980808 0,12374536 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0980808 0,1236805 ! body fluid secretion GO:0007589 31 20 0,000 0,0980808 0,12361571 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0980808 0,12355099 ! stem cell differentiation GO:0048863 53 20 0,000 0,0980808 0,12348634 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0980808 0,12342175 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0980808 0,12335724 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0980808 0,12329279 ! sensory perception of pain GO:0019233 30 20 0,000 0,0980808 0,1232284 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0980808 0,12316409 ! diencephalon development GO:0021536 34 20 0,000 0,0980808 0,12309984 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0980808 0,12303566 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0980808 0,12297154 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0980808 0,1229075 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0980808 0,12284352 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0980808 0,1227796 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0980808 0,12271575 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0980808 0,12265197 ! regulation of glucose import GO:0046324 29 20 0,000 0,0980808 0,12258826 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0980808 0,12252461 ! actin filament-based movement GO:0030048 43 20 0,000 0,0980808 0,12246102 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0980808 0,12239751 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0980808 0,12233406 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0980808 0,12227067 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0980808 0,12220735 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10272569 0,12792858 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10272569 0,1278624 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10272569 0,12779629 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10272569 0,12773024 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10272569 0,12766426 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10272569 0,12759836 ! axis specification GO:0009798 38 21 0,000 0,10272569 0,12753252 ! ovarian follicle development GO:0001541 35 21 0,000 0,10272569 0,12746674 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,10272569 0,12740104 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10272569 0,1273354 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10272569 0,12726983 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10272569 0,12720433 ! cytolysis GO:0019835 24 21 0,000 0,10272569 0,1271389 ! vasodilation GO:0042311 39 21 0,000 0,10272569 0,12707353 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10272569 0,12700823 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10272569 0,126943 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10272569 0,12687783 ! oogenesis GO:0048477 36 21 0,000 0,10272569 0,12681273 ! collagen fibril organization GO:0030199 59 21 0,000 0,10272569 0,1267477 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10272569 0,12668274 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10272569 0,12661784 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10272569 0,126553 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10272569 0,12648824 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10272569 0,12642354 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10272569 0,1263589 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10272569 0,12629434 ! collagen catabolic process GO:0030574 28 21 0,000 0,10272569 0,12622983 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10272569 0,1261654 ! gut development GO:0048565 39 21 0,000 0,10272569 0,12610103 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,10734682 0,1317065 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10734682 0,13163938 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10734682 0,13157231 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10734682 0,13150532 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10734682 0,1314384 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10734682 0,13137154 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10734682 0,13130476 ! regeneration GO:0031099 41 22 0,000 0,10734682 0,13123804 ! keratinization GO:0031424 28 22 0,000 0,10734682 0,13117138 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10734682 0,1311048 ! sensory perception of taste GO:0050909 28 22 0,000 0,10734682 0,13103828 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,10734682 0,13097183 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10734682 0,13090545 ! vacuolar transport GO:0007034 36 22 0,000 0,10734682 0,13083914 ! lysosome organization GO:0007040 41 22 0,000 0,10734682 0,13077289 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10734682 0,13070671 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10734682 0,13064059 ! fucose metabolic process GO:0006004 39 22 0,000 0,10734682 0,13057455 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10734682 0,13050857 ! ureteric bud development GO:0001657 43 22 0,000 0,10734682 0,13044265 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10734682 0,13037681 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10734682 0,13031103 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10734682 0,13024531 ! sarcomere organization GO:0045214 30 22 0,000 0,10734682 0,13017966 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10734682 0,13011408 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10734682 0,13004857 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10734682 0,12998312 ! gluconeogenesis GO:0006094 33 23 0,000 0,1119443 0,13548189 ! viral genome replication GO:0019079 41 23 0,000 0,1119443 0,13541377 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1119443 0,13534573 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1119443 0,13527775 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1119443 0,13520984 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1119443 0,135142 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1119443 0,13507422 ! visual behavior GO:0007632 42 23 0,000 0,1119443 0,13500652 ! response to ethanol GO:0045471 46 23 0,000 0,1119443 0,13493888 ! peroxisome organization GO:0007031 37 23 0,000 0,1119443 0,13487131 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1119443 0,1348038 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1119443 0,13473637 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,1119443 0,134669 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1119443 0,1346017 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,1119443 0,13453446 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,1119443 0,1344673 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1119443 0,1344002 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1119443 0,13433317 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1119443 0,1342662 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1119443 0,1341993 ! fatty acid transport GO:0015908 44 23 0,000 0,1119443 0,13413247 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1119443 0,1340657 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1119443 0,133999 ! cell-cell recognition GO:0009988 25 23 0,000 0,1119443 0,13393237 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1119443 0,1338658 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1119443 0,1337993 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1119443 0,13373287 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,11651826 0,13912801 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,11651826 0,139059 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,11651826 0,13899005 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,11651826 0,13892118 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11651826 0,13885237 ! vesicle docking GO:0048278 47 24 0,000 0,11651826 0,13878363 ! vacuole organization GO:0007033 43 24 0,000 0,11651826 0,13871496 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11651826 0,13864636 ! digestive system process GO:0022600 39 24 0,000 0,11651826 0,13857782 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,11651826 0,13850936 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11651826 0,13844096 ! membrane depolarization GO:0051899 39 24 0,000 0,11651826 0,13837262 ! pallium development GO:0021543 49 24 0,000 0,11651826 0,13830436 ! pentose metabolic process GO:0019321 35 24 0,000 0,11651826 0,13823616 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11651826 0,13816803 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11651826 0,13809997 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11651826 0,13803197 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11651826 0,13796404 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11651826 0,13789618 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11651826 0,13782839 ! regulation of amine transport GO:0051952 40 24 0,000 0,11651826 0,13776066 ! protein tetramerization GO:0051262 52 24 0,000 0,11651826 0,13769299 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12106881 0,14300027 ! phototransduction GO:0007602 33 25 0,000 0,12106881 0,14293011 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12106881 0,14286001 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,12106881 0,14278998 ! sperm motility GO:0030317 31 25 0,000 0,12106881 0,14272002 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12106881 0,14265013 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,12106881 0,1425803 ! chromosome condensation GO:0030261 45 25 0,000 0,12106881 0,14251055 ! response to starvation GO:0042594 42 25 0,000 0,12106881 0,14244086 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12106881 0,14237124 ! neural crest cell development GO:0014032 54 25 0,000 0,12106881 0,14230169 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12106881 0,14223221 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12106881 0,14216279 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12106881 0,14209344 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12106881 0,14202416 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12106881 0,14195495 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12106881 0,1418858 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12106881 0,14181673 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,12106881 0,14174772 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12106881 0,14167877 ! telomere organization GO:0032200 43 25 0,000 0,12106881 0,1416099 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12106881 0,14154109 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12106881 0,14147234 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12559607 0,14669133 ! embryonic pattern specification GO:0009880 44 26 0,000 0,12559607 0,14662016 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12559607 0,14654905 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12559607 0,14647802 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12559607 0,14640705 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,12559607 0,14633615 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12559607 0,14626532 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,12559607 0,14619456 ! molting cycle process GO:0022404 50 26 0,000 0,12559607 0,14612386 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,12559607 0,14605324 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12559607 0,14598268 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12559607 0,14591219 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12559607 0,14584177 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,12559607 0,14577142 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12559607 0,14570113 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12559607 0,14563091 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,12559607 0,14556076 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,12559607 0,14549068 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12559607 0,14542067 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,12559607 0,14535072 ! iron ion transport GO:0006826 59 27 0,000 0,13010016 0,15049086 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13010016 0,15041854 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13010016 0,1503463 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13010016 0,15027412 ! fat cell differentiation GO:0045444 50 27 0,000 0,13010016 0,15020201 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13010016 0,15012997 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,13010016 0,150058 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13010016 0,1499861 ! autophagy GO:0006914 41 27 0,000 0,13010016 0,14991427 ! response to toxin GO:0009636 47 27 0,000 0,13010016 0,1498425 ! primary neural tube formation GO:0014020 51 27 0,000 0,13010016 0,14977081 ! base-excision repair GO:0006284 41 27 0,000 0,13010016 0,14969918 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13010016 0,14962762 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13010016 0,14955613 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13010016 0,14948471 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13010016 0,14941336 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13010016 0,14934208 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,1345812 0,15441219 ! circadian rhythm GO:0007623 50 28 0,000 0,1345812 0,15433859 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,1345812 0,15426506 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,1345812 0,1541916 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,1345812 0,15411822 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,1345812 0,1540449 ! synaptogenesis GO:0007416 42 28 0,000 0,1345812 0,15397165 ! lipid oxidation GO:0034440 43 28 0,000 0,1345812 0,15389847 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,1345812 0,15382535 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,1345812 0,15375231 ! translational initiation GO:0006413 65 29 0,000 0,13903931 0,15877009 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,13903931 0,15869477 ! regulation of pH GO:0006885 43 29 0,000 0,13903931 0,15861952 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,13903931 0,15854435 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,13903931 0,15846924 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,13903931 0,15839421 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,13903931 0,15831925 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,13903931 0,15824436 ! cell fate determination GO:0001709 60 29 0,000 0,13903931 0,15816954 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,13903931 0,15809479 ! detection of light stimulus GO:0009583 38 29 0,000 0,13903931 0,15802011 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,13903931 0,1579455 ! tissue homeostasis GO:0001894 48 29 0,000 0,13903931 0,15787096 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,13903931 0,1577965 ! zinc ion transport GO:0006829 45 30 0,000 0,14347459 0,16275336 ! membrane docking GO:0022406 61 30 0,000 0,14347459 0,16267666 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14347459 0,16260003 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14347459 0,16252348 ! myofibril assembly GO:0030239 47 30 0,000 0,14347459 0,162447 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14347459 0,16237059 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14347459 0,16229425 ! phospholipid transport GO:0015914 51 30 0,000 0,14347459 0,16221798 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14347459 0,16214179 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,14347459 0,16206567 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14347459 0,16198962 ! eye morphogenesis GO:0048592 60 30 0,000 0,14347459 0,16191364 ! response to heat GO:0009408 50 30 0,000 0,14347459 0,16183773 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,14788718 0,1667369 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14788718 0,16665881 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,14788718 0,16658078 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,14788718 0,16650283 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,14788718 0,16642495 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,14788718 0,16634715 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14788718 0,16626942 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,14788718 0,16619176 ! ovulation cycle process GO:0022602 49 31 0,000 0,14788718 0,16611417 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14788718 0,16603665 ! mesoderm formation GO:0001707 69 31 0,000 0,14788718 0,16595921 ! natural killer cell activation GO:0030101 45 31 0,000 0,14788718 0,16588184 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,14788718 0,16580454 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,14788718 0,16572732 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,14788718 0,16565016 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15227718 0,17048808 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15227718 0,17040878 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15227718 0,17032956 ! cholesterol transport GO:0030301 56 32 0,000 0,15227718 0,17025041 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15227718 0,17017134 ! spliceosome assembly GO:0000245 67 32 0,000 0,15227718 0,17009233 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15227718 0,1700134 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15227718 0,16993455 ! response to ionizing radiation GO:0010212 65 32 0,000 0,15227718 0,16985576 ! muscle cell development GO:0055001 49 32 0,000 0,15227718 0,16977706 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15227718 0,16969842 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15227718 0,16961985 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15227718 0,16954136 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,15227718 0,16946294 ! ovulation cycle GO:0042698 51 32 0,000 0,15227718 0,1693846 ! BMP signaling pathway GO:0030509 64 32 0,000 0,15227718 0,16930632 ! hindbrain development GO:0030902 61 32 0,000 0,15227718 0,16922812 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15227718 0,16914999 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,15227718 0,16907194 ! gene silencing GO:0016458 65 32 0,000 0,15227718 0,16899395 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,1566447 0,17376079 ! post-embryonic development GO:0009791 69 33 0,000 0,1566447 0,17368072 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,1566447 0,17360072 ! protein targeting to membrane GO:0006612 68 33 0,000 0,1566447 0,17352079 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,1566447 0,17344094 ! ceramide metabolic process GO:0006672 64 33 0,000 0,1566447 0,17336116 ! formation of primary germ layer GO:0001704 72 33 0,000 0,1566447 0,17328145 ! sterol transport GO:0015918 57 33 0,000 0,1566447 0,17320182 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,1566447 0,17312226 ! adult locomotory behavior GO:0008344 59 33 0,000 0,1566447 0,17304277 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,1566447 0,17296336 ! glial cell differentiation GO:0010001 63 34 0,000 0,16098987 0,17767965 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16098987 0,17759818 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,16098987 0,17751679 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16098987 0,17743547 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16098987 0,17735423 ! mismatch repair GO:0006298 46 34 0,000 0,16098987 0,17727306 ! spermatid development GO:0007286 63 34 0,000 0,16098987 0,17719196 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16098987 0,17711094 ! regulation of muscle development GO:0048634 70 35 0,000 0,1653128 0,18178363 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,1653128 0,18170059 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,1653128 0,18161762 ! odontogenesis GO:0042476 66 35 0,000 0,1653128 0,18153473 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,1653128 0,18145191 ! female gonad development GO:0008585 58 35 0,000 0,1653128 0,18136917 ! telencephalon development GO:0021537 68 35 0,000 0,1653128 0,1812865 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,1653128 0,18120391 ! cytokine production GO:0001816 59 35 0,000 0,1653128 0,1811214 ! neural tube formation GO:0001841 67 35 0,000 0,1653128 0,18103896 ! vesicle localization GO:0051648 64 35 0,000 0,1653128 0,18095659 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,16961359 0,18557995 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,16961359 0,18549559 ! positive regulation of cell development GO:0010720 80 36 0,000 0,16961359 0,18541131 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,16961359 0,18532711 ! regulation of proteolysis GO:0030162 72 36 0,000 0,16961359 0,18524299 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,16961359 0,18515894 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,16961359 0,18507497 ! embryonic organ development GO:0048568 57 36 0,000 0,16961359 0,18499107 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,16961359 0,18490725 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17389237 0,18948598 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17389237 0,1894002 ! organic anion transport GO:0015711 68 37 0,000 0,17389237 0,1893145 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,17389237 0,18922887 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17389237 0,18914333 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17389237 0,18905786 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,17389237 0,18897247 ! spermatid differentiation GO:0048515 66 37 0,000 0,17389237 0,18888715 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,17814924 0,19342377 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,17814924 0,19333652 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,17814924 0,19324936 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,17814924 0,19316227 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,17814924 0,19307526 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,17814924 0,19298833 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,17814924 0,19290147 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,17814924 0,1928147 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,17814924 0,192728 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,17814924 0,19264138 ! mRNA catabolic process GO:0006402 71 39 0,000 0,18238432 0,19713237 ! learning GO:0007612 77 39 0,000 0,18238432 0,19704386 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18238432 0,19695542 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18238432 0,19686706 ! RNA modification GO:0009451 57 39 0,000 0,18238432 0,19677877 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18238432 0,19669057 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18659771 0,20114431 ! feeding behavior GO:0007631 59 40 0,000 0,18659771 0,20105423 ! mesenchymal cell development GO:0014031 87 40 0,000 0,18659771 0,20096423 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,18659771 0,20087431 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,19078953 0,20529499 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,19078953 0,20520322 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,19078953 0,20511153 ! gliogenesis GO:0042063 88 41 0,000 0,19078953 0,20501992 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,19078953 0,2049284 ! female gamete generation GO:0007292 61 41 0,000 0,19078953 0,20483695 ! polyol metabolic process GO:0019751 66 41 0,000 0,19078953 0,20474559 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,19078953 0,20465431 ! regulation of tube size GO:0035150 71 42 0,000 0,19495989 0,20903453 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,19495989 0,20894142 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,19495989 0,20884839 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,19495989 0,20875544 ! neuron migration GO:0001764 79 42 0,000 0,19495989 0,20866258 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,19910889 0,21300844 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,19910889 0,21291377 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,19910889 0,21281918 ! neural tube development GO:0021915 77 43 0,000 0,19910889 0,21272468 ! striated muscle contraction GO:0006941 77 43 0,000 0,19910889 0,21263026 ! phagocytosis GO:0006909 90 43 0,000 0,19910889 0,21253593 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,19910889 0,21244168 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,20323664 0,21674972 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,20323664 0,21665368 ! B cell differentiation GO:0030183 107 44 0,000 0,20323664 0,21655773 ! developmental growth GO:0048589 82 44 0,000 0,20323664 0,21646187 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,20734326 0,220738 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,20734326 0,22064037 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,20734326 0,22054283 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,20734326 0,22044538 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,20734326 0,22034801 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,20734326 0,22025072 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,21142885 0,22449153 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,21142885 0,2243925 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,21142885 0,22429357 ! response to calcium ion GO:0051592 81 47 0,000 0,21549351 0,2285048 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,21549351 0,22840414 ! JNK cascade GO:0007254 91 47 0,000 0,21549351 0,22830356 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,21549351 0,22820308 ! protein homooligomerization GO:0051260 76 47 0,000 0,21549351 0,22810268 ! mitochondrial transport GO:0006839 82 48 0,000 0,21953736 0,23228095 ! Notch signaling pathway GO:0007219 96 48 0,000 0,21953736 0,23217885 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,21953736 0,23207684 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,21953736 0,23197492 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,21953736 0,23187309 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,21953736 0,23177134 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2235605 0,23591516 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,2235605 0,23581173 ! regulation of ion transport GO:0043269 77 49 0,000 0,2235605 0,23570839 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,2235605 0,23560515 ! peptide metabolic process GO:0006518 76 49 0,000 0,2235605 0,235502 ! response to temperature stimulus GO:0009266 76 49 0,000 0,2235605 0,23539893 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2235605 0,23529596 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2235605 0,23519307 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,2235605 0,23509028 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,2235605 0,23498757 ! inner ear development GO:0048839 79 50 0,000 0,22756303 0,23909024 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,23154506 0,24316779 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,23154506 0,2430617 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,23154506 0,2429557 ! excretion GO:0007588 83 51 0,000 0,23154506 0,24284979 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,23154506 0,24274397 ! chromatin remodeling GO:0006338 109 51 0,000 0,23154506 0,24263825 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,23154506 0,24253261 ! vesicle organization GO:0016050 107 51 0,000 0,23154506 0,24242707 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,23154506 0,24232162 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,2355067 0,24636048 ! membrane fusion GO:0006944 110 52 0,000 0,2355067 0,24625342 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,2355067 0,24614644 ! amino acid activation GO:0043038 92 52 0,000 0,2355067 0,24603956 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! RNA catabolic process GO:0006401 93 53 0,000 0,23944804 0,2500486 ! regulation of translational initiation GO:0006446 82 53 0,000 0,23944804 0,24994012 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,23944804 0,24983173 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,23944804 0,24972344 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,23944804 0,24961524 ! cell maturation GO:0048469 100 53 0,000 0,23944804 0,24950714 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,23944804 0,24939913 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,23944804 0,24929121 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,24336919 0,25326396 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,24336919 0,25315446 ! chloride transport GO:0006821 90 55 0,000 0,24727026 0,25710123 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,24727026 0,25699017 ! gastrulation GO:0007369 112 55 0,000 0,24727026 0,25687921 ! heart morphogenesis GO:0003007 97 55 0,000 0,24727026 0,25676834 ! RNA elongation GO:0006354 79 55 0,000 0,24727026 0,25665757 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,24727026 0,25654689 ! regulation of actin filament length GO:0030832 105 56 0,000 0,25115134 0,26046126 ! sensory perception of smell GO:0007608 80 56 0,000 0,25115134 0,26034904 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,25115134 0,26023692 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,25115134 0,26012489 ! proton transport GO:0015992 94 56 0,000 0,25115134 0,26001296 ! hydrogen transport GO:0006818 97 58 0,000 0,25885396 0,2678721 ! adult behavior GO:0030534 99 58 0,000 0,25885396 0,26775693 ! regulation of cellular component size GO:0032535 109 59 0,000 0,2626757 0,27159335 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,2626757 0,27147669 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,26647786 0,27528799 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,26647786 0,27516984 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,26647786 0,27505179 ! regulation of heart contraction GO:0008016 110 60 0,000 0,26647786 0,27493384 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,27026053 0,27871704 ! mesoderm development GO:0007498 119 61 0,000 0,27026053 0,27859762 ! tRNA processing GO:0008033 89 61 0,000 0,27026053 0,27847831 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,27026053 0,27835909 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,27402383 0,28211439 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,27776784 0,28584663 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,27776784 0,28572442 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,28149267 0,28943221 ! cell redox homeostasis GO:0045454 102 64 0,000 0,28149267 0,28930857 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,28149267 0,28918504 ! single fertilization GO:0007338 75 64 0,000 0,28149267 0,28906162 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,28519841 0,29274206 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,28888516 0,29639987 ! extracellular matrix organization GO:0030198 133 66 0,000 0,28888516 0,29627353 ! secondary metabolic process GO:0019748 116 66 0,000 0,28888516 0,2961473 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,29255302 0,29977963 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,29255302 0,29965201 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,29255302 0,2995245 ! amino acid transport GO:0006865 125 68 0,000 0,29620208 0,30313152 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,29620208 0,30300264 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,29620208 0,30287387 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,29983244 0,30645576 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,29983244 0,30632563 ! amine catabolic process GO:0009310 117 71 0,000 0,30703744 0,31355351 ! B cell activation GO:0042113 160 71 0,000 0,30703744 0,31342048 ! regulation of blood pressure GO:0008217 125 73 0,000 0,31416876 0,32056406 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,31416876 0,32042817 ! fertilization GO:0009566 90 73 0,000 0,31416876 0,32029239 ! transition metal ion transport GO:0000041 126 74 0,000 0,31770704 0,32376244 ! neurotransmitter transport GO:0006836 123 74 0,000 0,31770704 0,32362537 ! exocytosis GO:0006887 133 74 0,000 0,31770704 0,32348842 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,31770704 0,32335158 ! rhythmic process GO:0048511 128 75 0,000 0,32122717 0,32679601 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,32472926 0,33021919 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,3282134 0,33362122 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,3282134 0,33348034 ! protein oligomerization GO:0051259 139 78 0,000 0,33167967 0,33685998 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,33512818 0,34021873 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,33512818 0,34007524 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,33512818 0,33993187 ! response to metal ion GO:0010038 140 80 0,000 0,338559 0,34326716 ! protein import into nucleus GO:0006606 158 80 0,000 0,338559 0,34312256 ! inorganic anion transport GO:0015698 138 80 0,000 0,338559 0,34297809 ! digestion GO:0007586 112 81 0,000 0,34197224 0,34629007 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,34197224 0,34614439 ! nuclear import GO:0051170 161 81 0,000 0,34197224 0,34599883 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,34536798 0,34928766 ! response to nutrient GO:0007584 125 82 0,000 0,34536798 0,3491409 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,3521073 0,35580435 ! response to unfolded protein GO:0006986 131 85 0,000 0,35545107 0,35903244 ! response to inorganic substance GO:0010035 153 86 0,000 0,35877769 0,3622405 ! tube morphogenesis GO:0035239 176 86 0,000 0,35877769 0,36208856 ! amine transport GO:0015837 155 86 0,000 0,35877769 0,36193674 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,36208725 0,36512235 ! protein localization in nucleus GO:0034504 176 87 0,000 0,36208725 0,36496939 ! regulation of neurological system process GO:0031644 148 88 0,000 0,36537984 0,36813396 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,36537984 0,36797987 ! cellular defense response GO:0006968 114 89 0,000 0,36865555 0,37112353 ! sterol metabolic process GO:0016125 152 91 0,000 0,37515664 0,3775102 ! response to protein stimulus GO:0051789 149 91 0,000 0,37515664 0,37735237 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,37515664 0,37719468 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,3783822 0,38027886 ! vitamin metabolic process GO:0006766 139 92 0,000 0,3783822 0,38012008 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,38159122 0,38318384 ! forebrain development GO:0030900 188 95 0,000 0,38795996 0,38941663 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,38795996 0,38925424 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,39111985 0,39226109 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,39111985 0,39209765 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,39426353 0,39508457 ! protein ubiquitination GO:0016567 217 97 0,000 0,39426353 0,39492009 ! hormone metabolic process GO:0042445 157 97 0,000 0,39426353 0,39475575 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,39739108 0,39772169 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,39739108 0,39755632 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,40050259 0,40050259