pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1234-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 5,000 1,368E-14 3,293E-11 ! myoblast cell fate commitment GO:0048625 16 6 2,000 1,737E-07 2,089E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 4,849E-07 3,889E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 4,849E-07 2,916E-04 ! BMP signaling pathway GO:0030509 64 32 3,000 5,981E-07 2,878E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 7,262E-07 2,912E-04 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 1,422E-06 4,888E-04 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 1,893E-06 5,694E-04 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 3,000 2,018E-06 5,394E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 3,898E-06 9,38E-04 ! myoblast differentiation GO:0045445 45 17 2,000 5,809E-06 1,271E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 8,253E-06 1,655E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 9,695E-06 1,794E-03 ! pancreas development GO:0031016 35 20 2,000 9,695E-06 1,666E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 3,000 1,207E-05 1,936E-03 ! negative regulation of ligase activity GO:0051352 112 68 3,000 1,28E-05 1,925E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 1,28E-05 1,812E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,306E-05 1,745E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 1,357E-05 1,718E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 1,607E-05 1,934E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 1,607E-05 1,842E-03 ! cell-matrix adhesion GO:0007160 163 75 3,000 1,89E-05 2,067E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 1,941E-05 2,031E-03 ! positive regulation of ligase activity GO:0051351 124 77 3,000 2,098E-05 2,103E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,191E-05 2,109E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 2,322E-05 2,149E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 2,322E-05 2,069E-03 ! fat cell differentiation GO:0045444 50 27 2,000 2,462E-05 2,115E-03 ! cell-substrate adhesion GO:0031589 171 81 3,000 2,563E-05 2,126E-03 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 2,69E-05 2,158E-03 ! regulation of ligase activity GO:0051340 142 84 3,000 2,959E-05 2,296E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 3,066E-05 2,305E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 4,414E-05 3,218E-03 GO:0010498|proteasomal protein catabolic process, ! androgen receptor signaling pathway GO:0030521 74 36 2,000 5,929E-05 4,195E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 6,425E-05 4,417E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! interaction with symbiont GO:0051702 13 6 1,000 6,425E-05 4,294E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 6,442E-05 4,189E-03 ! carbohydrate homeostasis GO:0033500 53 38 2,000 6,984E-05 4,422E-03 GO:0042593|glucose homeostasis, ! regulation of hormone secretion GO:0046883 62 40 2,000 8,155E-05 5,031E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 8,155E-05 4,905E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of lipid kinase activity GO:0043550 13 7 1,000 8,983E-05 5,271E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 8,983E-05 5,146E-03 ! transcription from RNA polymerase I promoter GO:0006360 13 7 1,000 8,983E-05 5,026E-03 ! transcription termination GO:0006353 13 7 1,000 8,983E-05 4,912E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 9,448E-05 5,051E-03 ! ER overload response GO:0006983 12 8 1,000 1,196E-04 6,256E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 1,196E-04 6,123E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,242E-04 6,225E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 1,242E-04 6,098E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,242E-04 5,976E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,536E-04 7,245E-03 ! chromatin remodeling GO:0006338 109 51 2,000 1,691E-04 7,824E-03 ! midbrain development GO:0030901 13 10 1,000 1,917E-04 8,703E-03 ! skeletal muscle fiber development GO:0048741 111 56 2,000 2,234E-04 9,954E-03 ! muscle fiber development GO:0048747 112 57 2,000 2,355E-04 0,01030091 ! regulation of intracellular transport GO:0032386 101 57 2,000 2,355E-04 0,01011696 ! positive regulation of secretion GO:0051047 95 59 2,000 2,608E-04 0,01101029 ! protein complex disassembly GO:0043241 27 12 1,000 2,804E-04 0,01163242 GO:0043624|cellular protein complex disassembly, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,804E-04 0,01143526 ! focal adhesion formation GO:0048041 35 12 1,000 2,804E-04 0,01124467 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,879E-04 0,01135609 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 3,167E-04 0,01229143 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 3,968E-04 0,01515259 ! cell killing GO:0001906 29 15 1,000 4,443E-04 0,01670343 ! regulation of caspase activity GO:0043281 122 72 2,000 4,694E-04 0,01737363 ! complement activation, alternative pathway GO:0006957 18 16 1,000 5,071E-04 0,01848621 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,071E-04 0,0182103 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 5,086E-04 0,01799703 ! regulation of peptidase activity GO:0052547 134 79 2,000 6,159E-04 0,02147616 ! muscle cell differentiation GO:0042692 159 80 2,000 6,389E-04 0,02196146 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,448E-04 0,02185105 ! cell-substrate junction assembly GO:0007044 54 18 1,000 6,448E-04 0,02154757 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 6,448E-04 0,02125239 ! lipid phosphorylation GO:0046834 35 19 1,000 7,197E-04 0,02340013 ! actin filament bundle formation GO:0051017 42 19 1,000 7,197E-04 0,02308812 ! peptidyl-serine modification GO:0018209 43 20 1,000 7,986E-04 0,02528182 ! regulation of protein transport GO:0051223 154 87 2,000 8,158E-04 0,02549027 GO:0070201|regulation of establishment of protein localization, ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 8,815E-04 0,02718991 ! cytolysis GO:0019835 24 21 1,000 8,815E-04 0,02684573 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 8,815E-04 0,02651016 ! viral genome replication GO:0019079 41 23 1,000 1,059E-03 0,03145924 ! regulation of protein localization GO:0032880 176 97 2,000 1,118E-03 0,03280423 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,186E-03 0,03437498 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 2,000 1,221E-03 0,03496429 ! negative regulation of DNA replication GO:0008156 42 25 1,000 1,252E-03 0,03545234 ! osteoblast differentiation GO:0001649 60 25 1,000 1,252E-03 0,03504011 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,252E-03 0,03463735 ! interaction with host GO:0051701 62 25 1,000 1,252E-03 0,03424374 ! embryonic pattern specification GO:0009880 44 26 1,000 1,355E-03 0,03663119 ! macromolecular complex disassembly GO:0032984 53 26 1,000 1,355E-03 0,03622418 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,355E-03 0,03582611 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 1,355E-03 0,0354367 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,572E-03 0,04066277 ! complement activation, classical pathway GO:0006958 48 29 1,000 1,686E-03 0,04315208 ! cell junction assembly GO:0034329 78 30 1,000 1,804E-03 0,04568615 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 1,926E-03 0,04826321 ! mesoderm formation GO:0001707 69 31 1,000 1,926E-03 0,04776565 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,051E-03 0,05036231 ! hindbrain development GO:0030902 61 32 1,000 2,051E-03 0,0498536 ! formation of primary germ layer GO:0001704 72 33 1,000 2,181E-03 0,05246863 ! mesoderm morphogenesis GO:0048332 76 34 1,000 2,314E-03 0,05512176 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 2,314E-03 0,05458135 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 2,451E-03 0,05725022 ! cell junction organization GO:0034330 86 36 1,000 2,592E-03 0,05995434 ! glycerol ether metabolic process GO:0006662 53 37 1,000 2,736E-03 0,06269232 ! glycogen metabolic process GO:0005977 61 37 1,000 2,736E-03 0,06210089 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 2,884E-03 0,06485106 GO:0006956|complement activation, ! glucan metabolic process GO:0044042 62 38 1,000 2,884E-03 0,06425059 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 3,036E-03 0,06701214 ! organic ether metabolic process GO:0018904 55 39 1,000 3,036E-03 0,06640294 ! hormone-mediated signaling GO:0009755 74 41 1,000 3,351E-03 0,07262486 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 3,68E-03 0,07904915 ! energy reserve metabolic process GO:0006112 74 43 1,000 3,68E-03 0,0783496 ! protein homooligomerization GO:0051260 76 47 1,000 4,382E-03 0,0924731 ! cellular component disassembly GO:0022411 86 48 1,000 4,566E-03 0,09552627 ! activation of caspase activity GO:0006919 84 48 1,000 4,566E-03 0,09470277 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 4,754E-03 0,0977575 GO:0019724|B cell mediated immunity, ! regulation of ossification GO:0030278 117 50 1,000 4,945E-03 0,10083235 ! viral infectious cycle GO:0019058 99 51 1,000 5,14E-03 0,10392649 ! excretion GO:0007588 83 51 1,000 5,14E-03 0,10306044 ! positive regulation of caspase activity GO:0043280 95 55 1,000 5,955E-03 0,11840607 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 5,955E-03 0,11743553 ! gastrulation GO:0007369 112 55 1,000 5,955E-03 0,11648077 ! negative regulation of cell motion GO:0051271 134 55 1,000 5,955E-03 0,11554141 ! regulation of DNA replication GO:0006275 101 56 1,000 6,167E-03 0,11870289 ! regulation of bone remodeling GO:0046850 137 57 1,000 6,383E-03 0,1218795 ! positive regulation of cell migration GO:0030335 126 57 1,000 6,383E-03 0,12091982 ! lipid modification GO:0030258 97 57 1,000 6,383E-03 0,11997514 ! regulation of tissue remodeling GO:0034103 140 58 1,000 6,602E-03 0,12313155 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 6,824E-03 0,12630216 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 6,824E-03 0,12533802 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 7,05E-03 0,12850543 ! mesoderm development GO:0007498 119 61 1,000 7,279E-03 0,13168603 ! viral reproductive process GO:0022415 126 62 1,000 7,512E-03 0,13487927 ! regulation of mitosis GO:0007088 105 63 1,000 7,748E-03 0,13808459 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 7,748E-03 0,13706927 ! cell redox homeostasis GO:0045454 102 64 1,000 7,987E-03 0,14027009 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 7,987E-03 0,13925364 ! positive regulation of cell motion GO:0051272 146 64 1,000 7,987E-03 0,13825182 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 8,475E-03 0,14565701 ! actin filament organization GO:0007015 148 66 1,000 8,475E-03 0,14462398 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 8,725E-03 0,14782612 ! adaptive immune response GO:0002250 119 67 1,000 8,725E-03 0,14679237 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 8,725E-03 0,14577298 ! negative regulation of kinase activity GO:0033673 131 68 1,000 8,977E-03 0,14895504 ! viral reproduction GO:0016032 134 68 1,000 8,977E-03 0,1479348 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 8,977E-03 0,14692844 ! cAMP-mediated signaling GO:0019933 120 69 1,000 9,233E-03 0,15009098 ! humoral immune response GO:0006959 109 71 1,000 9,753E-03 0,15749483 ! acute inflammatory response GO:0002526 113 72 1,000 0,01001868 0,16069962 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01001868 0,15963538 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,01001868 0,15858515 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01041623 0,16380034 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01041623 0,16273671 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01041623 0,16168679 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01041623 0,16065034 ! neuron fate determination GO:0048664 7 5 0,000 0,01041623 0,15962709 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01041623 0,15861679 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01041623 0,1576192 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01041623 0,15663408 ! polyol transport GO:0015791 12 5 0,000 0,01041623 0,1556612 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01041623 0,15470032 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01041623 0,15375124 ! response to superoxide GO:0000303 10 5 0,000 0,01041623 0,15281374 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01041623 0,15188759 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01041623 0,15097261 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01041623 0,15006858 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01041623 0,14917531 ! female meiosis GO:0007143 7 5 0,000 0,01041623 0,14829262 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01041623 0,14742031 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01041623 0,1465582 ! cobalt ion transport GO:0006824 11 5 0,000 0,01041623 0,14570612 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01041623 0,14486389 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01041623 0,14403134 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01041623 0,1432083 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01041623 0,14239462 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01041623 0,14159013 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01041623 0,14079468 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01041623 0,14000812 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01041623 0,13923029 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01041623 0,13846106 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01041623 0,13770029 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01041623 0,13694783 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01041623 0,13620355 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01041623 0,13546731 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01041623 0,13473899 ! negative chemotaxis GO:0050919 14 5 0,000 0,01041623 0,13401846 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01041623 0,1333056 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01041623 0,13260028 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01041623 0,13190238 ! behavioral response to pain GO:0048266 9 5 0,000 0,01041623 0,13121179 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01041623 0,1305284 ! Notch receptor processing GO:0007220 8 5 0,000 0,01041623 0,12985209 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01041623 0,12918275 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01041623 0,12852027 ! micturition GO:0060073 9 5 0,000 0,01041623 0,12786455 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01041623 0,1272155 ! copulation GO:0007620 9 5 0,000 0,01041623 0,12657299 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01041623 0,12593695 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01041623 0,12530726 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01041623 0,12468384 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01041623 0,1240666 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01041623 0,12345543 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01041623 0,12285026 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01041623 0,12225099 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01041623 0,12165754 ! grooming behavior GO:0007625 6 5 0,000 0,01041623 0,12106982 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01041623 0,12048775 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01041623 0,11991126 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01041623 0,11934025 ! response to protozoan GO:0001562 10 5 0,000 0,01041623 0,11877466 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01041623 0,1182144 ! lymph vessel development GO:0001945 10 5 0,000 0,01041623 0,1176594 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01041623 0,11710959 ! endochondral ossification GO:0001958 16 5 0,000 0,01041623 0,1165649 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01041623 0,11602524 ! parathyroid gland development GO:0060017 13 5 0,000 0,01041623 0,11549057 ! anagen GO:0042640 6 5 0,000 0,01041623 0,11496079 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01041623 0,11443586 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01041623 0,11391569 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01041623 0,11340024 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01041623 0,11288943 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01041623 0,1123832 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01041623 0,11188148 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01041623 0,11138423 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01041623 0,11089138 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01041623 0,11040287 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01041623 0,10991865 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01041623 0,10943866 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01041623 0,10896284 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01041623 0,10849114 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01041623 0,1080235 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01041623 0,10755988 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01041623 0,10710022 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01041623 0,10664448 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01041623 0,1061926 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01041623 0,10574453 ! histidine catabolic process GO:0006548 6 5 0,000 0,01041623 0,10530022 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01041623 0,10485963 ! microvillus organization GO:0032528 7 5 0,000 0,01041623 0,10442272 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01041623 0,10398943 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01041623 0,10355972 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01041623 0,10313355 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01041623 0,10271087 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01041623 0,10229164 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01041623 0,10187582 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01041623 0,10146337 ! polyol catabolic process GO:0046174 7 5 0,000 0,01041623 0,10105424 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01041623 0,1006484 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01041623 0,10024581 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01041623 0,09984642 ! muscle cell migration GO:0014812 8 5 0,000 0,01041623 0,09945021 ! mitochondrial fission GO:0000266 8 5 0,000 0,01041623 0,09905712 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01041623 0,09866714 ! mRNA transcription GO:0009299 9 5 0,000 0,01041623 0,09828021 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01041623 0,0978963 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01041623 0,09751538 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01041623 0,09713741 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01041623 0,09676237 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01041623 0,0963902 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01041623 0,09602089 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01041623 0,0956544 ! response to food GO:0032094 6 5 0,000 0,01041623 0,09529069 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01041623 0,09492974 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01041623 0,09457152 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01041623 0,09421599 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01041623 0,09386312 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01041623 0,09351288 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01041623 0,09316525 ! forebrain neuron development GO:0021884 13 5 0,000 0,01041623 0,09282019 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01041623 0,09247768 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01041623 0,09213769 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01041623 0,09180019 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01041623 0,09146516 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01041623 0,09113255 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01041623 0,09080236 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01041623 0,09047456 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01041623 0,09014911 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01041623 0,089826 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01041623 0,08950519 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01041623 0,08918666 ! basic amino acid transport GO:0015802 11 5 0,000 0,01041623 0,0888704 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01041623 0,08855637 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01041623 0,08824455 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01041623 0,08793492 ! depyrimidination GO:0045008 10 5 0,000 0,01041623 0,08762746 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01041623 0,08732213 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01041623 0,08701893 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01041623 0,08671783 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01041623 0,0864188 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01041623 0,08612183 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01041623 0,08582689 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01041623 0,08553397 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01041623 0,08524304 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01041623 0,08495408 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01041623 0,08466707 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01041623 0,084382 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01041623 0,08409883 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01041623 0,08381757 ! response to arsenic GO:0046685 10 5 0,000 0,01041623 0,08353818 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01041623 0,08326064 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01041623 0,08298494 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01041623 0,08271106 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01041623 0,08243899 ! response to cadmium ion GO:0046686 7 5 0,000 0,01041623 0,0821687 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01041623 0,08190017 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01041623 0,0816334 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01041623 0,08136835 ! decidualization GO:0046697 11 5 0,000 0,01041623 0,08110502 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01041623 0,0808434 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01041623 0,08058345 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01041623 0,08032517 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01041623 0,08006854 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01041623 0,07981354 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01041623 0,07956017 ! neural tube patterning GO:0021532 7 5 0,000 0,01041623 0,07930839 ! embryonic cleavage GO:0040016 6 5 0,000 0,01041623 0,07905821 ! peroxisome fission GO:0016559 5 5 0,000 0,01041623 0,0788096 ! histone demethylation GO:0016577 10 5 0,000 0,01041623 0,07856255 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01041623 0,07831704 ! mitotic recombination GO:0006312 9 5 0,000 0,01041623 0,07807306 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01041623 0,0778306 ! metaphase plate congression GO:0051310 7 5 0,000 0,01041623 0,07758964 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01041623 0,07735016 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01041623 0,07711216 ! enteric nervous system development GO:0048484 8 5 0,000 0,01041623 0,07687562 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01041623 0,07664053 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01041623 0,07640687 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01041623 0,07617463 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01041623 0,0759438 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01041623 0,07571436 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01041623 0,0754863 ! plasminogen activation GO:0031639 5 5 0,000 0,01041623 0,07525962 ! B cell homeostasis GO:0001782 13 5 0,000 0,01041623 0,07503429 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01041623 0,07481031 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01041623 0,07458766 ! metaphase GO:0051323 8 5 0,000 0,01041623 0,07436633 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01041623 0,07414631 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01041623 0,07392759 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01041623 0,07371015 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01041623 0,073494 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01041623 0,0732791 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01041623 0,07306546 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01041623 0,07285306 ! response to redox state GO:0051775 5 5 0,000 0,01041623 0,07264189 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01041623 0,07243194 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01041623 0,07222321 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01041623 0,07201567 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01041623 0,07180932 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01041623 0,07160415 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01041623 0,07140015 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01041623 0,07119731 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01041623 0,07099562 ! striatum development GO:0021756 9 5 0,000 0,01041623 0,07079506 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01041623 0,07059564 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01041623 0,07039734 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01041623 0,07020015 ! glial cell migration GO:0008347 11 5 0,000 0,01041623 0,07000406 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01041623 0,06980906 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01041623 0,06961515 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01041623 0,06942231 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01041623 0,06923053 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01041623 0,06903981 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01041623 0,06885014 ! neuroprotection GO:0043526 6 5 0,000 0,01041623 0,06866151 ! neural plate development GO:0001840 8 5 0,000 0,01041623 0,06847391 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01041623 0,06828734 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01041623 0,06810177 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01041623 0,06791722 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01041623 0,06773366 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01041623 0,06755109 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01041623 0,0673695 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01041623 0,06718888 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01041623 0,06700923 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01041623 0,06683054 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01041623 0,0666528 ! spindle assembly GO:0051225 6 5 0,000 0,01041623 0,066476 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01041623 0,06630014 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01041623 0,0661252 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01041623 0,06595119 ! drug metabolic process GO:0017144 6 5 0,000 0,01041623 0,06577809 ! stem cell division GO:0017145 11 5 0,000 0,01041623 0,0656059 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01041623 0,0654346 ! organ regeneration GO:0031100 7 5 0,000 0,01041623 0,0652642 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01041623 0,06509468 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01041623 0,06492604 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01041623 0,06475828 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,01055875 0,06547515 ! blood coagulation GO:0007596 146 78 1,000 0,01167673 0,07222162 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 1,000 0,01167673 0,07203644 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01248663 0,07683587 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01248663 0,07663986 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01248663 0,07644485 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01248663 0,07625083 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01248663 0,07605779 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01248663 0,07586572 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01248663 0,07567463 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01248663 0,07548449 ! sleep GO:0030431 13 6 0,000 0,01248663 0,0752953 ! response to oxygen radical GO:0000305 11 6 0,000 0,01248663 0,07510707 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01248663 0,07491977 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01248663 0,0747334 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01248663 0,07454796 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01248663 0,07436343 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01248663 0,07417982 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01248663 0,07399711 ! forebrain regionalization GO:0021871 8 6 0,000 0,01248663 0,0738153 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01248663 0,07363438 ! male meiosis GO:0007140 7 6 0,000 0,01248663 0,07345434 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01248663 0,07327519 ! response to zinc ion GO:0010043 9 6 0,000 0,01248663 0,0730969 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01248663 0,07291948 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01248663 0,07274292 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01248663 0,07256721 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01248663 0,07239235 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01248663 0,07221833 ! malate metabolic process GO:0006108 11 6 0,000 0,01248663 0,07204515 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01248663 0,07187279 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01248663 0,07170126 ! protein refolding GO:0042026 15 6 0,000 0,01248663 0,07153054 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01248663 0,07136063 ! opsonization GO:0008228 8 6 0,000 0,01248663 0,07119153 ! mating behavior GO:0007617 7 6 0,000 0,01248663 0,07102323 ! neuron remodeling GO:0016322 15 6 0,000 0,01248663 0,07085572 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01248663 0,070689 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01248663 0,07052307 ! equilibrioception GO:0050957 14 6 0,000 0,01248663 0,07035791 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01248663 0,07019352 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01248663 0,0700299 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01248663 0,06986704 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01248663 0,06970493 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01248663 0,06954358 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01248663 0,06938297 ! toxin metabolic process GO:0009404 11 6 0,000 0,01248663 0,0692231 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01248663 0,06906397 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01248663 0,06890557 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01248663 0,06874789 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01248663 0,06859093 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01248663 0,06843468 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01248663 0,06827915 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01248663 0,06812432 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01248663 0,0679702 ! thymic T cell selection GO:0045061 12 6 0,000 0,01248663 0,06781676 ! protein lipoylation GO:0009249 10 6 0,000 0,01248663 0,06766402 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01248663 0,06751197 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01248663 0,0673606 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01248663 0,0672099 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01248663 0,06705988 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01248663 0,06691053 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,01248663 0,06676184 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01248663 0,06661381 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01248663 0,06646643 ! hyperosmotic response GO:0006972 9 6 0,000 0,01248663 0,06631971 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01248663 0,06617363 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01248663 0,06602819 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01248663 0,06588339 ! urea metabolic process GO:0019627 7 6 0,000 0,01248663 0,06573923 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01248663 0,06559569 ! neutrophil activation GO:0042119 8 6 0,000 0,01248663 0,06545278 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01248663 0,06531049 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01248663 0,06516882 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01248663 0,06502776 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01248663 0,06488731 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01248663 0,06474747 ! neuron apoptosis GO:0051402 9 6 0,000 0,01248663 0,06460823 ! nucleoside salvage GO:0043174 9 6 0,000 0,01248663 0,06446958 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01248663 0,06433153 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01248663 0,06419407 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01248663 0,0640572 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01248663 0,06392091 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01248663 0,06378519 ! carnitine transport GO:0015879 10 6 0,000 0,01248663 0,06365006 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01248663 0,06351549 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01248663 0,06338149 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01248663 0,06324806 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01248663 0,06311518 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01248663 0,06298286 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01248663 0,0628511 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01248663 0,06271989 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01248663 0,06258922 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01248663 0,0624591 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01248663 0,06232952 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01248663 0,06220047 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01248663 0,06207196 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01248663 0,06194397 ! neural nucleus development GO:0048857 14 6 0,000 0,01248663 0,06181652 ! response to UV-C GO:0010225 11 6 0,000 0,01248663 0,06168958 ! astrocyte development GO:0014002 15 6 0,000 0,01248663 0,06156317 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01248663 0,06143727 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01248663 0,06131189 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01248663 0,06118702 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01248663 0,06106266 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01248663 0,0609388 ! response to copper ion GO:0046688 10 6 0,000 0,01248663 0,06081544 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01248663 0,06069258 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01248663 0,06057021 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01248663 0,06044834 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01248663 0,06032696 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01248663 0,06020607 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01248663 0,06008565 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01248663 0,05996572 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01248663 0,05984627 ! hair follicle maturation GO:0048820 7 6 0,000 0,01248663 0,05972729 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01248663 0,05960878 ! Schwann cell development GO:0014044 15 6 0,000 0,01248663 0,05949075 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01248663 0,05937317 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01248663 0,05925607 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01248663 0,05913942 ! subpallium development GO:0021544 10 6 0,000 0,01248663 0,05902323 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01248663 0,0589075 ! histone ubiquitination GO:0016574 8 6 0,000 0,01248663 0,05879222 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01248663 0,0586774 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01248663 0,05856301 ! G2 phase GO:0051319 16 6 0,000 0,01248663 0,05844908 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01248663 0,05833559 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01248663 0,05822253 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01248663 0,05810992 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01248663 0,05799773 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01248663 0,05788599 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01248663 0,05777467 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01248663 0,05766377 ! receptor internalization GO:0031623 10 6 0,000 0,01248663 0,05755331 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01248663 0,05744326 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01248663 0,05733364 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01248663 0,05722443 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01248663 0,05711564 ! protein deubiquitination GO:0016579 14 6 0,000 0,01248663 0,05700726 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01248663 0,05689929 ! protein destabilization GO:0031648 9 6 0,000 0,01248663 0,05679173 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01248663 0,05668458 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01248663 0,05657783 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01248663 0,05647148 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01248663 0,05636553 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01248663 0,05625997 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01248663 0,05615482 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01248663 0,05605005 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01248663 0,05594567 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01248663 0,05584168 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01248663 0,05573808 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01248663 0,05563486 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01248663 0,05553203 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01248663 0,05542957 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01248663 0,05532749 ! catecholamine transport GO:0051937 9 6 0,000 0,01248663 0,05522578 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01248663 0,05512445 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01248663 0,05502349 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01248663 0,0549229 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01248663 0,05482268 ! maternal placenta development GO:0001893 12 6 0,000 0,01248663 0,05472282 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01248663 0,05462332 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01248663 0,05452419 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01248663 0,05442541 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01248663 0,05432699 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01248663 0,05422893 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01248663 0,05413122 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01248663 0,05403386 ! hemostasis GO:0007599 158 84 1,000 0,01344661 0,05808354 ! nucleosome assembly GO:0006334 122 85 1,000 0,01375225 0,05929733 ! chromatin assembly GO:0031497 124 86 1,000 0,0140609 0,06051973 ! tRNA transcription GO:0009304 14 7 0,000 0,01455276 0,0625249 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01455276 0,06241345 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01455276 0,06230239 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01455276 0,06219173 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01455276 0,06208146 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01455276 0,06197158 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01455276 0,06186209 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01455276 0,06175299 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01455276 0,06164427 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01455276 0,06153593 ! prostate gland development GO:0030850 13 7 0,000 0,01455276 0,06142797 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01455276 0,06132039 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01455276 0,06121319 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01455276 0,06110636 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01455276 0,0609999 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01455276 0,06089381 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01455276 0,0607881 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01455276 0,06068274 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01455276 0,06057776 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01455276 0,06047313 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01455276 0,06036887 ! glycolipid transport GO:0046836 10 7 0,000 0,01455276 0,06026496 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01455276 0,06016141 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01455276 0,06005822 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01455276 0,05995538 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01455276 0,05985289 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01455276 0,05975076 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01455276 0,05964897 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01455276 0,05954752 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01455276 0,05944642 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01455276 0,05934567 ! mRNA stabilization GO:0048255 18 7 0,000 0,01455276 0,05924525 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01455276 0,05914517 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01455276 0,05904544 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01455276 0,05894603 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01455276 0,05884696 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01455276 0,05874823 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01455276 0,05864982 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01455276 0,05855174 ! lipoprotein transport GO:0042953 14 7 0,000 0,01455276 0,058454 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01455276 0,05835657 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01455276 0,05825947 ! rhythmic behavior GO:0007622 15 7 0,000 0,01455276 0,0581627 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01455276 0,05806624 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01455276 0,0579701 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01455276 0,05787429 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01455276 0,05777878 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01455276 0,0576836 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01455276 0,05758872 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01455276 0,05749416 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01455276 0,05739991 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01455276 0,05730596 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01455276 0,05721233 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01455276 0,05711899 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01455276 0,05702597 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01455276 0,05693324 ! spinal cord patterning GO:0021511 13 7 0,000 0,01455276 0,05684082 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01455276 0,05674869 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01455276 0,05665687 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01455276 0,05656534 ! adrenal gland development GO:0030325 17 7 0,000 0,01455276 0,0564741 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01455276 0,05638316 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01455276 0,05629251 ! ovulation GO:0030728 9 7 0,000 0,01455276 0,05620216 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01455276 0,05611209 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01455276 0,05602231 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01455276 0,05593282 ! microtubule nucleation GO:0007020 20 7 0,000 0,01455276 0,05584361 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01455276 0,05575469 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01455276 0,05566605 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01455276 0,05557769 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01455276 0,05548961 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01455276 0,05540181 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01455276 0,05531429 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01455276 0,05522704 ! galactose metabolic process GO:0006012 13 7 0,000 0,01455276 0,05514007 ! vesicle fusion GO:0006906 17 7 0,000 0,01455276 0,05505337 ! response to dietary excess GO:0002021 8 7 0,000 0,01455276 0,05496694 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01455276 0,05488079 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01455276 0,0547949 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01455276 0,05470929 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01455276 0,05462394 ! organ growth GO:0035265 15 7 0,000 0,01455276 0,05453885 ! purine salvage GO:0043101 10 7 0,000 0,01455276 0,05445403 ! nucleoside transport GO:0015858 8 7 0,000 0,01455276 0,05436948 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01455276 0,05428518 ! parturition GO:0007567 14 7 0,000 0,01455276 0,05420115 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01455276 0,05411738 ! rRNA modification GO:0000154 14 7 0,000 0,01455276 0,05403386 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01455276 0,05395061 ! spindle checkpoint GO:0031577 15 7 0,000 0,01455276 0,05386761 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01455276 0,05378486 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01455276 0,05370237 ! macrophage differentiation GO:0030225 11 7 0,000 0,01455276 0,05362013 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01455276 0,05353814 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01455276 0,0534564 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01455276 0,05337491 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01455276 0,05329367 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01455276 0,05321268 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01455276 0,05313193 ! fibrinolysis GO:0042730 10 7 0,000 0,01455276 0,05305143 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01455276 0,05297117 ! eating behavior GO:0042755 7 7 0,000 0,01455276 0,05289115 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01455276 0,05281138 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01455276 0,05273184 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01455276 0,05265255 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01455276 0,05257349 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01455276 0,05249467 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01455276 0,05241608 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01455276 0,05233773 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01455276 0,05225962 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01455276 0,05218173 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01455276 0,05210408 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01455276 0,05202666 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01455276 0,05194947 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01455276 0,05187251 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01455276 0,05179577 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01455276 0,05171927 ! regulation of meiosis GO:0040020 12 7 0,000 0,01455276 0,05164298 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 0,000 0,01455276 0,05156693 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01455276 0,05149109 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01455276 0,05141548 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01455276 0,05134009 ! response to tumor cell GO:0002347 13 7 0,000 0,01455276 0,05126492 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01455276 0,05118998 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01455276 0,05111525 ! anaphase GO:0051322 17 7 0,000 0,01455276 0,05104073 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01455276 0,05096644 ! axonal fasciculation GO:0007413 18 7 0,000 0,01455276 0,05089236 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01455276 0,0508185 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01455276 0,05074485 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01455276 0,05067141 ! diuresis GO:0030146 12 7 0,000 0,01455276 0,05059818 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01455276 0,05052517 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01455276 0,05045237 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01455276 0,05037977 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01455276 0,05030739 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01455276 0,05023521 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01455276 0,05016324 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01455276 0,05009148 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01455276 0,05001992 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01455276 0,04994856 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01455276 0,04987741 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01455276 0,04980646 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01455276 0,04973572 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01455276 0,04966517 ! lymph node development GO:0048535 10 7 0,000 0,01455276 0,04959482 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01455276 0,04952467 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01455276 0,04945472 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01455276 0,04938497 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01455276 0,04931541 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01455276 0,04924605 ! adult feeding behavior GO:0008343 9 7 0,000 0,01455276 0,04917689 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01455276 0,04910791 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01455276 0,04903914 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01455276 0,04897055 ! muscle adaptation GO:0043500 14 7 0,000 0,01455276 0,04890216 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01455276 0,04883395 ! retina homeostasis GO:0001895 12 7 0,000 0,01455276 0,04876594 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01455276 0,04869811 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01455276 0,04863048 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01455276 0,04856303 ! protein prenylation GO:0018342 18 7 0,000 0,01455276 0,04849577 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01455276 0,04842869 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01455276 0,0483618 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01455276 0,04829509 ! gland development GO:0048732 206 88 1,000 0,01468719 0,04867406 ! ossification GO:0001503 188 90 1,000 0,01532535 0,05071911 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,01532535 0,05064944 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,01532535 0,05057996 ! bone development GO:0060348 189 91 1,000 0,01564885 0,0515769 ! nucleosome organization GO:0034728 138 92 1,000 0,01597529 0,05258076 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01661464 0,05461042 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01661464 0,05453591 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01661464 0,05446161 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01661464 0,05438752 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01661464 0,05431362 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01661464 0,05423992 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01661464 0,05416643 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01661464 0,05409313 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01661464 0,05402003 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01661464 0,05394713 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01661464 0,05387443 ! meiotic prophase I GO:0007128 13 8 0,000 0,01661464 0,05380192 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01661464 0,0537296 ! oligopeptide transport GO:0006857 15 8 0,000 0,01661464 0,05365748 ! UTP metabolic process GO:0046051 8 8 0,000 0,01661464 0,05358556 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01661464 0,05351382 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01661464 0,05344228 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01661464 0,05337093 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01661464 0,05329977 ! succinate metabolic process GO:0006105 14 8 0,000 0,01661464 0,05322879 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01661464 0,05315801 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01661464 0,05308742 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01661464 0,05301701 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01661464 0,05294679 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01661464 0,05287675 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01661464 0,0528069 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01661464 0,05273724 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01661464 0,05266775 ! reflex GO:0060004 16 8 0,000 0,01661464 0,05259845 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01661464 0,05252934 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01661464 0,0524604 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01661464 0,05239164 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01661464 0,05232307 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01661464 0,05225467 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01661464 0,05218645 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01661464 0,05211841 ! pigment granule organization GO:0048753 16 8 0,000 0,01661464 0,05205055 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01661464 0,05198287 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01661464 0,05191536 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01661464 0,05184802 ! histidine metabolic process GO:0006547 16 8 0,000 0,01661464 0,05178086 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01661464 0,05171387 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01661464 0,05164706 ! glycine catabolic process GO:0006546 13 8 0,000 0,01661464 0,05158042 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01661464 0,05151395 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01661464 0,05144765 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01661464 0,05138152 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01661464 0,05131556 ! melanin metabolic process GO:0006582 15 8 0,000 0,01661464 0,05124977 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01661464 0,05118415 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01661464 0,0511187 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01661464 0,05105342 ! macrophage activation GO:0042116 12 8 0,000 0,01661464 0,0509883 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01661464 0,05092334 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01661464 0,05085855 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01661464 0,05079393 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01661464 0,05072947 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01661464 0,05066518 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01661464 0,05060104 ! osteoblast development GO:0002076 16 8 0,000 0,01661464 0,05053707 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01661464 0,05047326 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01661464 0,05040961 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01661464 0,05034613 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01661464 0,0502828 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01661464 0,05021963 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01661464 0,05015662 ! response to UV-B GO:0010224 16 8 0,000 0,01661464 0,05009376 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01661464 0,05003107 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01661464 0,04996853 ! intermediate filament organization GO:0045109 12 8 0,000 0,01661464 0,04990615 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01661464 0,04984392 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01661464 0,04978185 ! cellular extravasation GO:0045123 12 8 0,000 0,01661464 0,04971993 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01661464 0,04965817 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01661464 0,04959656 ! response to antibiotic GO:0046677 11 8 0,000 0,01661464 0,0495351 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01661464 0,04947379 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01661464 0,04941264 ! DNA topological change GO:0006265 12 8 0,000 0,01661464 0,04935163 ! response to tropane GO:0014073 15 8 0,000 0,01661464 0,04929078 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01661464 0,04923008 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01661464 0,04916953 ! melanosome transport GO:0032402 13 8 0,000 0,01661464 0,04910912 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01661464 0,04904886 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01661464 0,04898876 ! mast cell activation GO:0045576 14 8 0,000 0,01661464 0,04892879 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01661464 0,04886898 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01661464 0,04880931 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01661464 0,04874979 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01661464 0,04869041 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01661464 0,04863117 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01661464 0,04857208 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01661464 0,04851314 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01661464 0,04845433 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01661464 0,04839567 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01661464 0,04833715 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01661464 0,04827877 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01661464 0,04822054 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01661464 0,04816244 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01661464 0,04810448 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01661464 0,04804666 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01661464 0,04798898 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01661464 0,04793144 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01661464 0,04787404 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01661464 0,04781678 ! hormone catabolic process GO:0042447 17 8 0,000 0,01661464 0,04775965 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01661464 0,04770265 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01661464 0,0476458 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01661464 0,04758908 ! ATP catabolic process GO:0006200 11 8 0,000 0,01661464 0,04753249 ! blastocyst growth GO:0001832 19 8 0,000 0,01661464 0,04747604 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01661464 0,04741972 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01661464 0,04736354 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01661464 0,04730748 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01661464 0,04725157 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01661464 0,04719578 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01661464 0,04714012 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01661464 0,0470846 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01661464 0,0470292 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01661464 0,04697394 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01661464 0,04691881 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01661464 0,0468638 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01661464 0,04680893 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01661464 0,04675418 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01661464 0,04669956 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01661464 0,04664507 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01661464 0,0465907 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01661464 0,04653647 ! transcription initiation GO:0006352 153 94 1,000 0,01663689 0,0465446 ! mRNA transport GO:0051028 169 96 1,000 0,01731005 0,04837165 ! positive regulation of immune response GO:0050778 156 96 1,000 0,01731005 0,04831553 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,01765094 0,04920992 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,01834125 0,05107528 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01867227 0,05193698 ! axon extension GO:0048675 15 9 0,000 0,01867227 0,05187701 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01867227 0,05181717 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01867227 0,05175748 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01867227 0,05169792 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01867227 0,05163849 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01867227 0,05157921 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01867227 0,05152006 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01867227 0,05146104 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01867227 0,05140216 ! phosphate transport GO:0006817 19 9 0,000 0,01867227 0,05134342 ! reproductive behavior GO:0019098 19 9 0,000 0,01867227 0,05128481 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01867227 0,05122633 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01867227 0,05116798 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01867227 0,05110977 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01867227 0,05105169 ! GTP metabolic process GO:0046039 9 9 0,000 0,01867227 0,05099375 ! RNA methylation GO:0001510 15 9 0,000 0,01867227 0,05093593 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01867227 0,05087824 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01867227 0,05082069 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01867227 0,05076327 ! artery development GO:0060840 24 9 0,000 0,01867227 0,05070597 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01867227 0,0506488 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01867227 0,05059177 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01867227 0,05053486 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01867227 0,05047808 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01867227 0,05042142 ! chemosensory behavior GO:0007635 20 9 0,000 0,01867227 0,0503649 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01867227 0,0503085 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01867227 0,05025223 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01867227 0,05019608 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01867227 0,05014006 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01867227 0,05008416 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01867227 0,05002838 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01867227 0,04997274 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01867227 0,04991721 ! protein targeting to ER GO:0045047 22 9 0,000 0,01867227 0,04986181 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01867227 0,04980653 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01867227 0,04975137 ! T cell selection GO:0045058 23 9 0,000 0,01867227 0,04969634 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01867227 0,04964143 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01867227 0,04958663 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01867227 0,04953196 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01867227 0,04947741 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01867227 0,04942298 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01867227 0,04936867 ! mannose metabolic process GO:0006013 13 9 0,000 0,01867227 0,04931448 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01867227 0,04926041 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01867227 0,04920645 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01867227 0,04915261 ! receptor clustering GO:0043113 18 9 0,000 0,01867227 0,0490989 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01867227 0,04904529 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01867227 0,04899181 ! ruffle organization GO:0031529 15 9 0,000 0,01867227 0,04893844 ! retinol metabolic process GO:0042572 18 9 0,000 0,01867227 0,04888519 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01867227 0,04883205 ! behavioral fear response GO:0001662 22 9 0,000 0,01867227 0,04877903 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01867227 0,04872613 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01867227 0,04867334 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01867227 0,04862066 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01867227 0,0485681 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01867227 0,04851565 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01867227 0,04846331 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01867227 0,04841109 ! segment specification GO:0007379 13 9 0,000 0,01867227 0,04835898 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01867227 0,04830698 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01867227 0,04825509 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01867227 0,04820332 ! response to amine stimulus GO:0014075 13 9 0,000 0,01867227 0,04815165 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01867227 0,0481001 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01867227 0,04804865 ! erythrocyte development GO:0048821 15 9 0,000 0,01867227 0,04799732 ! gas homeostasis GO:0033483 16 9 0,000 0,01867227 0,04794609 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01867227 0,04789498 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01867227 0,04784397 ! renal water homeostasis GO:0003091 14 9 0,000 0,01867227 0,04779307 ! postreplication repair GO:0006301 22 9 0,000 0,01867227 0,04774228 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01867227 0,0476916 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01867227 0,04764103 ! icosanoid secretion GO:0032309 15 9 0,000 0,01867227 0,04759056 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01867227 0,0475402 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01867227 0,04748995 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01867227 0,0474398 ! regulation of cell division GO:0051302 15 9 0,000 0,01867227 0,04738976 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01867227 0,04733982 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01867227 0,04728999 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01867227 0,04724026 ! sterol catabolic process GO:0016127 11 9 0,000 0,01867227 0,04719064 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01867227 0,04714112 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01867227 0,04709171 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01867227 0,0470424 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01867227 0,04699319 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01867227 0,04694409 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01867227 0,04689508 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01867227 0,04684618 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01867227 0,04679739 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01867227 0,04674869 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01867227 0,04670009 ! purine base metabolic process GO:0006144 21 9 0,000 0,01867227 0,0466516 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01867227 0,04660321 ! pigment granule transport GO:0051904 17 9 0,000 0,01867227 0,04655491 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01867227 0,04650672 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01867227 0,04645862 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01867227 0,04641063 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01867227 0,04636273 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01867227 0,04631494 ! mitochondrion localization GO:0051646 15 9 0,000 0,01867227 0,04626724 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02072567 0,05130243 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02072567 0,0512497 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02072567 0,05119708 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02072567 0,05114457 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02072567 0,05109217 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02072567 0,05103988 ! synapsis GO:0007129 13 10 0,000 0,02072567 0,05098769 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02072567 0,05093561 ! N-glycan processing GO:0006491 20 10 0,000 0,02072567 0,05088363 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02072567 0,05083176 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02072567 0,05078 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02072567 0,05072834 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02072567 0,05067679 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02072567 0,05062534 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02072567 0,050574 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02072567 0,05052276 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02072567 0,05047162 ! androgen metabolic process GO:0008209 17 10 0,000 0,02072567 0,05042059 ! phospholipid efflux GO:0033700 16 10 0,000 0,02072567 0,05036966 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02072567 0,05031883 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02072567 0,05026811 ! lung alveolus development GO:0048286 26 10 0,000 0,02072567 0,05021748 ! pathogenesis GO:0009405 13 10 0,000 0,02072567 0,05016696 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02072567 0,05011654 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02072567 0,05006623 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02072567 0,05001601 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02072567 0,04996589 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02072567 0,04991588 ! endoderm development GO:0007492 16 10 0,000 0,02072567 0,04986596 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02072567 0,04981614 ! arginine catabolic process GO:0006527 13 10 0,000 0,02072567 0,04976643 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02072567 0,04971681 ! proline metabolic process GO:0006560 13 10 0,000 0,02072567 0,04966729 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02072567 0,04961787 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02072567 0,04956855 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02072567 0,04951933 ! V(D)J recombination GO:0033151 28 10 0,000 0,02072567 0,0494702 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02072567 0,04942117 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02072567 0,04937224 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02072567 0,0493234 ! B cell proliferation GO:0042100 18 10 0,000 0,02072567 0,04927466 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02072567 0,04922602 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02072567 0,04917748 ! multicellular organism growth GO:0035264 18 10 0,000 0,02072567 0,04912903 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02072567 0,04908067 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02072567 0,04903241 ! epithelial cell development GO:0002064 20 10 0,000 0,02072567 0,04898424 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02072567 0,04893617 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02072567 0,0488882 ! macroautophagy GO:0016236 17 10 0,000 0,02072567 0,04884031 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02072567 0,04879252 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02072567 0,04874483 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02072567 0,04869723 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02072567 0,04864972 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02072567 0,0486023 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02072567 0,04855498 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02072567 0,04850774 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02072567 0,0484606 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02072567 0,04841355 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02072567 0,0483666 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02072567 0,04831973 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02072567 0,04827295 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02072567 0,04822627 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02072567 0,04817967 ! response to dsRNA GO:0043331 20 10 0,000 0,02072567 0,04813317 ! DNA ligation GO:0006266 19 10 0,000 0,02072567 0,04808675 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02072567 0,04804042 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02072567 0,04799419 ! melanosome localization GO:0032400 16 10 0,000 0,02072567 0,04794804 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02072567 0,04790198 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02072567 0,04785601 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02072567 0,04781013 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02072567 0,04776433 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02072567 0,04771862 ! mRNA cleavage GO:0006379 17 10 0,000 0,02072567 0,047673 ! protein sumoylation GO:0016925 15 10 0,000 0,02072567 0,04762747 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02072567 0,04758202 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02072567 0,04753666 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02072567 0,04749139 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02072567 0,0474462 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02072567 0,0474011 ! salivary gland development GO:0007431 27 10 0,000 0,02072567 0,04735609 ! prophase GO:0051324 15 10 0,000 0,02072567 0,04731116 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02072567 0,04726631 ! apical protein localization GO:0045176 15 10 0,000 0,02072567 0,04722155 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02072567 0,04717688 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02072567 0,04713229 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02072567 0,04708778 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02072567 0,04704336 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02072567 0,04699902 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02072567 0,04695476 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02072567 0,04691059 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02072567 0,0468665 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02072567 0,0468225 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02072567 0,04677857 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02072567 0,04673473 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02072567 0,04669097 ! oocyte development GO:0048599 17 10 0,000 0,02072567 0,0466473 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02072567 0,0466037 ! blastocyst formation GO:0001825 17 10 0,000 0,02072567 0,04656019 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02072567 0,04651675 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02072567 0,0464734 ! activation of innate immune response GO:0002218 12 10 0,000 0,02072567 0,04643013 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02072567 0,04638694 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02072567 0,04634383 ! response to nicotine GO:0035094 20 10 0,000 0,02072567 0,0463008 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02072567 0,04625785 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02072567 0,04621498 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02072567 0,04617219 ! localization within membrane GO:0051668 20 10 0,000 0,02072567 0,04612947 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02277484 0,05064349 ! respiratory burst GO:0045730 17 11 0,000 0,02277484 0,05059673 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02277484 0,05055005 ! neuron fate specification GO:0048665 17 11 0,000 0,02277484 0,05050346 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02277484 0,05045696 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02277484 0,05041054 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02277484 0,05036421 ! thyroid gland development GO:0030878 26 11 0,000 0,02277484 0,05031796 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,02277484 0,0502718 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02277484 0,05022572 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02277484 0,05017972 ! response to pain GO:0048265 24 11 0,000 0,02277484 0,05013381 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02277484 0,05008799 ! T cell proliferation GO:0042098 26 11 0,000 0,02277484 0,05004224 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02277484 0,04999659 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02277484 0,04995101 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02277484 0,04990552 ! bone resorption GO:0045453 16 11 0,000 0,02277484 0,04986011 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02277484 0,04981478 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02277484 0,04976953 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02277484 0,04972437 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02277484 0,04967929 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02277484 0,04963429 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02277484 0,04958937 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02277484 0,04954454 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02277484 0,04949978 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02277484 0,04945511 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02277484 0,04941051 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02277484 0,049366 ! lipid digestion GO:0044241 18 11 0,000 0,02277484 0,04932156 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02277484 0,04927721 ! UV protection GO:0009650 19 11 0,000 0,02277484 0,04923294 ! adult heart development GO:0007512 14 11 0,000 0,02277484 0,04918874 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02277484 0,04914463 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02277484 0,04910059 ! temperature homeostasis GO:0001659 17 11 0,000 0,02277484 0,04905663 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02277484 0,04901275 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02277484 0,04896895 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02277484 0,04892523 ! regulation of organ growth GO:0046620 13 11 0,000 0,02277484 0,04888159 ! pigment granule localization GO:0051875 20 11 0,000 0,02277484 0,04883802 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02277484 0,04879453 ! vasoconstriction GO:0042310 18 11 0,000 0,02277484 0,04875112 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02277484 0,04870778 ! embryonic axis specification GO:0000578 18 11 0,000 0,02277484 0,04866453 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02277484 0,04862135 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02277484 0,04857824 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02277484 0,04853521 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02277484 0,04849226 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02277484 0,04844939 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02277484 0,04840659 ! zymogen activation GO:0031638 15 11 0,000 0,02277484 0,04836386 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02277484 0,04832121 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02277484 0,04827864 ! nucleosome positioning GO:0016584 15 11 0,000 0,02277484 0,04823614 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02277484 0,04819372 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02277484 0,04815137 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02277484 0,04810909 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02277484 0,04806689 ! acid secretion GO:0046717 18 11 0,000 0,02277484 0,04802477 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02277484 0,04798271 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02277484 0,04794073 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02277484 0,04789883 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02277484 0,04785699 ! oocyte differentiation GO:0009994 18 11 0,000 0,02277484 0,04781523 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02277484 0,04777355 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02277484 0,04773193 ! cholesterol efflux GO:0033344 19 11 0,000 0,02277484 0,04769039 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02277484 0,04764892 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02277484 0,04760752 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02277484 0,0475662 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02277484 0,04752494 ! embryonic gut development GO:0048566 15 11 0,000 0,02277484 0,04748376 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02277484 0,04744265 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02277484 0,04740161 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02277484 0,04736064 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02277484 0,04731974 ! defense response to fungus GO:0050832 13 11 0,000 0,02277484 0,04727891 ! developmental induction GO:0031128 19 11 0,000 0,02277484 0,04723815 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02277484 0,04719747 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02277484 0,04715685 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02277484 0,0471163 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02277484 0,04707582 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02277484 0,04703541 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02277484 0,04699507 ! nucleus localization GO:0051647 19 11 0,000 0,02277484 0,0469548 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02277484 0,0469146 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02481978 0,05108332 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02481978 0,05103966 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02481978 0,05099607 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02481978 0,05095256 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02481978 0,05090912 ! virus-host interaction GO:0019048 29 12 0,000 0,02481978 0,05086576 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02481978 0,05082247 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02481978 0,05077925 ! cartilage condensation GO:0001502 20 12 0,000 0,02481978 0,05073611 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02481978 0,05069304 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02481978 0,05065004 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02481978 0,05060712 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02481978 0,05056427 ! hippocampus development GO:0021766 26 12 0,000 0,02481978 0,05052149 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02481978 0,05047878 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02481978 0,05043615 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02481978 0,05039359 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02481978 0,0503511 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02481978 0,05030868 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02481978 0,05026633 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02481978 0,05022405 ! drug transport GO:0015893 16 12 0,000 0,02481978 0,05018185 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02481978 0,05013971 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02481978 0,05009765 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02481978 0,05005566 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02481978 0,05001374 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02481978 0,04997188 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02481978 0,0499301 ! forebrain cell migration GO:0021885 21 12 0,000 0,02481978 0,04988839 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02481978 0,04984675 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02481978 0,04980517 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02481978 0,04976367 ! entry into host cell GO:0030260 32 12 0,000 0,02481978 0,04972223 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02481978 0,04968087 ! monoamine transport GO:0015844 18 12 0,000 0,02481978 0,04963957 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02481978 0,04959834 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02481978 0,04955718 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02481978 0,04951609 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02481978 0,04947506 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02481978 0,04943411 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02481978 0,04939322 ! protein homotetramerization GO:0051289 21 12 0,000 0,02481978 0,0493524 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02481978 0,04931164 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02481978 0,04927096 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02481978 0,04923034 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02481978 0,04918979 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02481978 0,0491493 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02481978 0,04910888 ! cranial nerve development GO:0021545 20 12 0,000 0,02481978 0,04906853 ! fucose catabolic process GO:0019317 22 12 0,000 0,02481978 0,04902824 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02481978 0,04898802 ! histone acetylation GO:0016573 26 12 0,000 0,02481978 0,04894787 ! histone methylation GO:0016571 26 12 0,000 0,02481978 0,04890778 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02481978 0,04886776 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02481978 0,0488278 ! gland morphogenesis GO:0022612 29 12 0,000 0,02481978 0,04878791 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02481978 0,04874808 ! T cell homeostasis GO:0043029 25 12 0,000 0,02481978 0,04870832 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02481978 0,04866862 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02481978 0,04862899 ! spleen development GO:0048536 22 12 0,000 0,02481978 0,04858942 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02481978 0,04854992 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02481978 0,04851048 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02481978 0,0484711 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02481978 0,04843179 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02481978 0,04839255 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02481978 0,04835336 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02481978 0,04831424 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02481978 0,04827518 ! response to cold GO:0009409 17 12 0,000 0,02481978 0,04823619 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02481978 0,04819726 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02481978 0,04815839 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02686052 0,05207608 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02686052 0,05203415 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02686052 0,05199229 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02686052 0,05195049 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02686052 0,05190876 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02686052 0,0518671 ! lipid localization GO:0010876 28 13 0,000 0,02686052 0,05182551 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02686052 0,05178398 ! organelle fusion GO:0048284 32 13 0,000 0,02686052 0,05174252 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02686052 0,05170113 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02686052 0,0516598 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02686052 0,05161854 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02686052 0,05157734 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02686052 0,05153621 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02686052 0,05149515 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02686052 0,05145415 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02686052 0,05141321 ! methionine metabolic process GO:0006555 27 13 0,000 0,02686052 0,05137235 ! plasma membrane organization GO:0007009 24 13 0,000 0,02686052 0,05133154 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02686052 0,0512908 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02686052 0,05125013 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02686052 0,05120952 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02686052 0,05116897 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02686052 0,05112849 ! response to X-ray GO:0010165 25 13 0,000 0,02686052 0,05108807 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02686052 0,05104772 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02686052 0,05100743 ! exocrine system development GO:0035272 32 13 0,000 0,02686052 0,0509672 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02686052 0,05092704 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02686052 0,05088694 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02686052 0,0508469 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02686052 0,05080693 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02686052 0,05076702 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02686052 0,05072717 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02686052 0,05068738 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02686052 0,05064766 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02686052 0,050608 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02686052 0,0505684 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02686052 0,05052886 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02686052 0,05048938 ! ribosome assembly GO:0042255 17 13 0,000 0,02686052 0,05044997 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02686052 0,05041062 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02686052 0,05037133 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02686052 0,0503321 ! chromatin silencing GO:0006342 26 13 0,000 0,02686052 0,05029293 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02686052 0,05025382 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02686052 0,05021477 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02686052 0,05017578 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02686052 0,05013686 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02686052 0,05009799 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02686052 0,05005919 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02686052 0,05002044 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02686052 0,04998176 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02686052 0,04994313 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02686052 0,04990456 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02686052 0,04986606 ! embryonic placenta development GO:0001892 23 13 0,000 0,02686052 0,04982761 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02686052 0,04978922 ! insulin secretion GO:0030073 23 13 0,000 0,02686052 0,04975089 ! actin filament polymerization GO:0030041 24 13 0,000 0,02686052 0,04971262 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02686052 0,04967441 ! acrosome reaction GO:0007340 18 13 0,000 0,02686052 0,04963626 ! rRNA transcription GO:0009303 25 14 0,000 0,02889705 0,05335864 ! lactation GO:0007595 26 14 0,000 0,02889705 0,05331772 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02889705 0,05327687 ! reproductive cellular process GO:0048610 20 14 0,000 0,02889705 0,05323607 ! tRNA modification GO:0006400 20 14 0,000 0,02889705 0,05319534 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02889705 0,05315467 ! regulation of S phase GO:0033261 23 14 0,000 0,02889705 0,05311406 ! water transport GO:0006833 21 14 0,000 0,02889705 0,05307352 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02889705 0,05303304 ! non-recombinational repair GO:0000726 25 14 0,000 0,02889705 0,05299261 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02889705 0,05295225 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02889705 0,05291196 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02889705 0,05287172 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02889705 0,05283154 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02889705 0,05279143 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02889705 0,05275137 ! palate development GO:0060021 31 14 0,000 0,02889705 0,05271138 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02889705 0,05267145 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02889705 0,05263157 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02889705 0,05259176 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02889705 0,05255201 ! arginine metabolic process GO:0006525 17 14 0,000 0,02889705 0,05251232 ! regulation of heart rate GO:0002027 24 14 0,000 0,02889705 0,05247269 ! organic alcohol transport GO:0015850 29 14 0,000 0,02889705 0,05243311 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02889705 0,0523936 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02889705 0,05235415 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02889705 0,05231475 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02889705 0,05227542 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02889705 0,05223615 ! L-amino acid transport GO:0015807 30 14 0,000 0,02889705 0,05219693 ! bone mineralization GO:0030282 17 14 0,000 0,02889705 0,05215777 ! stem cell development GO:0048864 43 14 0,000 0,02889705 0,05211867 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02889705 0,05207963 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02889705 0,05204065 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02889705 0,05200173 ! cerebellum development GO:0021549 21 14 0,000 0,02889705 0,05196286 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02889705 0,05192405 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02889705 0,05188531 ! response to gamma radiation GO:0010332 28 14 0,000 0,02889705 0,05184661 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02889705 0,05180798 ! cofactor transport GO:0051181 26 14 0,000 0,02889705 0,0517694 ! NADP metabolic process GO:0006739 24 14 0,000 0,02889705 0,05173088 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02889705 0,05169242 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02889705 0,05165402 ! intestinal absorption GO:0050892 25 14 0,000 0,02889705 0,05161567 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02889705 0,05157738 ! oxygen transport GO:0015671 21 14 0,000 0,02889705 0,05153915 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02889705 0,05150097 ! male genitalia development GO:0030539 24 14 0,000 0,02889705 0,05146285 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02889705 0,05142478 ! regulation of axon extension GO:0030516 37 14 0,000 0,02889705 0,05138678 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02889705 0,05134883 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02889705 0,05131093 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03092939 0,05487914 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03092939 0,0548387 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03092939 0,05479832 ! superoxide anion generation GO:0042554 20 15 0,000 0,03092939 0,054758 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03092939 0,05471773 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03092939 0,05467753 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03092939 0,05463738 ! copper ion transport GO:0006825 20 15 0,000 0,03092939 0,0545973 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03092939 0,05455727 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03092939 0,0545173 ! sulfate transport GO:0008272 23 15 0,000 0,03092939 0,05447739 ! response to cAMP GO:0051591 22 15 0,000 0,03092939 0,05443754 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03092939 0,05439775 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03092939 0,05435801 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03092939 0,05431833 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03092939 0,05427871 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03092939 0,05423915 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03092939 0,05419965 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03092939 0,0541602 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03092939 0,05412081 ! pituitary gland development GO:0021983 29 15 0,000 0,03092939 0,05408148 ! vesicle coating GO:0006901 33 15 0,000 0,03092939 0,0540422 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03092939 0,05400299 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03092939 0,05396383 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03092939 0,05392472 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03092939 0,05388567 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03092939 0,05384668 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03092939 0,05380775 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03092939 0,05376887 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03092939 0,05373005 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03092939 0,05369128 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03092939 0,05365257 ! histone deacetylation GO:0016575 20 15 0,000 0,03092939 0,05361392 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03092939 0,05357532 ! tissue regeneration GO:0042246 26 15 0,000 0,03092939 0,05353677 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03092939 0,05349829 ! water homeostasis GO:0030104 27 15 0,000 0,03092939 0,05345985 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03092939 0,05342148 ! muscle maintenance GO:0046716 26 15 0,000 0,03092939 0,05338315 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03092939 0,05334489 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03092939 0,05330667 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03092939 0,05326852 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03092939 0,05323041 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03092939 0,05319236 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03092939 0,05315437 ! detection of bacterium GO:0016045 18 15 0,000 0,03092939 0,05311643 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03092939 0,05307854 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03092939 0,05304071 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03092939 0,05300293 ! peptide hormone processing GO:0016486 23 15 0,000 0,03092939 0,05296521 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03295754 0,05639819 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03295754 0,0563581 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03295754 0,05631808 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03295754 0,05627811 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03295754 0,05623819 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03295754 0,05619834 ! bone remodeling GO:0046849 27 16 0,000 0,03295754 0,05615853 ! filopodium assembly GO:0046847 32 16 0,000 0,03295754 0,05611879 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03295754 0,0560791 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03295754 0,05603947 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03295754 0,05599989 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03295754 0,05596037 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03295754 0,05592091 ! startle response GO:0001964 28 16 0,000 0,03295754 0,0558815 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03295754 0,05584215 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03295754 0,05580285 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03295754 0,05576361 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03295754 0,05572442 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03295754 0,05568529 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03295754 0,05564621 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03295754 0,05560719 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03295754 0,05556822 ! response to osmotic stress GO:0006970 25 16 0,000 0,03295754 0,05552931 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03295754 0,05549045 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03295754 0,05545164 ! fructose metabolic process GO:0006000 25 16 0,000 0,03295754 0,05541289 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03295754 0,0553742 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03295754 0,05533556 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03295754 0,05529697 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03295754 0,05525843 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03295754 0,05521995 ! axon cargo transport GO:0008088 43 16 0,000 0,03295754 0,05518152 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03295754 0,05514315 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03295754 0,05510483 ! DNA replication initiation GO:0006270 27 16 0,000 0,03295754 0,05506656 ! neuron recognition GO:0008038 35 16 0,000 0,03295754 0,05502835 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03295754 0,05499019 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03295754 0,05495208 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03295754 0,05491402 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03295754 0,05487602 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03295754 0,05483807 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03295754 0,05480017 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03295754 0,05476233 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03295754 0,05472453 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03295754 0,05468679 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03295754 0,0546491 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03295754 0,05461147 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03295754 0,05457388 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03295754 0,05453635 ! defense response to virus GO:0051607 37 16 0,000 0,03295754 0,05449887 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03498152 0,057806 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03498152 0,05776632 ! metencephalon development GO:0022037 30 17 0,000 0,03498152 0,0577267 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03498152 0,05768714 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03498152 0,05764763 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03498152 0,05760817 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03498152 0,05756877 ! signal complex assembly GO:0007172 41 17 0,000 0,03498152 0,05752942 ! endothelial cell migration GO:0043542 28 17 0,000 0,03498152 0,05749012 ! inositol metabolic process GO:0006020 28 17 0,000 0,03498152 0,05745088 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03498152 0,05741169 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03498152 0,05737255 ! glial cell development GO:0021782 27 17 0,000 0,03498152 0,05733347 ! limbic system development GO:0021761 36 17 0,000 0,03498152 0,05729444 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03498152 0,05725547 ! adult walking behavior GO:0007628 33 17 0,000 0,03498152 0,05721654 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03498152 0,05717767 ! heart looping GO:0001947 30 17 0,000 0,03498152 0,05713886 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03498152 0,05710009 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03498152 0,05706138 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03498152 0,05702272 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03498152 0,05698411 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03498152 0,05694556 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03498152 0,05690706 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03498152 0,0568686 ! glycine metabolic process GO:0006544 28 17 0,000 0,03498152 0,05683021 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,03498152 0,05679186 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03498152 0,05675356 ! NAD metabolic process GO:0019674 29 17 0,000 0,03498152 0,05671532 ! membrane budding GO:0006900 37 17 0,000 0,03498152 0,05667713 ! DNA integration GO:0015074 29 17 0,000 0,03498152 0,05663899 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03498152 0,0566009 ! regulation of protein binding GO:0043393 33 17 0,000 0,03498152 0,05656286 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03498152 0,05652487 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03498152 0,05648694 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03498152 0,05644905 ! genitalia development GO:0048806 30 17 0,000 0,03498152 0,05641122 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03498152 0,05637343 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03498152 0,0563357 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03498152 0,05629802 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03498152 0,05626038 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03498152 0,0562228 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03498152 0,05618527 ! steroid catabolic process GO:0006706 31 17 0,000 0,03498152 0,05614779 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03498152 0,05611036 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03498152 0,05607297 ! gas transport GO:0015669 25 17 0,000 0,03498152 0,05603564 ! organic cation transport GO:0015695 31 17 0,000 0,03498152 0,05599836 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03498152 0,05596113 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03498152 0,05592394 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03498152 0,05588681 ! microspike assembly GO:0030035 36 17 0,000 0,03498152 0,05584972 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03498152 0,05581269 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03498152 0,0557757 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03700133 0,05895708 ! neuron maturation GO:0042551 42 18 0,000 0,03700133 0,05891806 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03700133 0,05887909 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03700133 0,05884018 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03700133 0,05880131 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03700133 0,0587625 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03700133 0,05872374 ! memory GO:0007613 31 18 0,000 0,03700133 0,05868503 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03700133 0,05864637 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03700133 0,05860776 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03700133 0,0585692 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03700133 0,0585307 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03700133 0,05849224 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03700133 0,05845383 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03700133 0,05841548 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03700133 0,05837717 ! response to retinoic acid GO:0032526 26 18 0,000 0,03700133 0,05833892 ! response to fungus GO:0009620 21 18 0,000 0,03700133 0,05830071 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03700133 0,05826256 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03700133 0,05822445 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03700133 0,0581864 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03700133 0,05814839 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03700133 0,05811044 ! vitamin transport GO:0051180 27 18 0,000 0,03700133 0,05807253 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03700133 0,05803467 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03700133 0,05799687 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03700133 0,05795911 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03700133 0,0579214 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03700133 0,05788374 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03700133 0,05784613 ! nerve development GO:0021675 28 18 0,000 0,03700133 0,05780856 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03700133 0,05777105 ! protein secretion GO:0009306 39 19 0,000 0,03901697 0,06087862 ! positive regulation of translation GO:0045727 30 19 0,000 0,03901697 0,06083917 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03901697 0,06079976 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03901697 0,06076041 ! skin development GO:0043588 36 19 0,000 0,03901697 0,06072111 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03901697 0,06068186 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03901697 0,06064266 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03901697 0,06060351 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03901697 0,06056441 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03901697 0,06052536 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03901697 0,06048636 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03901697 0,06044741 ! cerebral cortex development GO:0021987 36 19 0,000 0,03901697 0,06040851 ! pigmentation during development GO:0048066 41 19 0,000 0,03901697 0,06036967 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03901697 0,06033087 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03901697 0,06029212 ! heme metabolic process GO:0042168 36 19 0,000 0,03901697 0,06025342 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03901697 0,06021477 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03901697 0,06017617 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03901697 0,06013762 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03901697 0,06009912 ! peptide cross-linking GO:0018149 37 19 0,000 0,03901697 0,06006067 ! protein export from nucleus GO:0006611 36 19 0,000 0,03901697 0,06002227 ! heart process GO:0003015 30 19 0,000 0,03901697 0,05998392 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03901697 0,05994561 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03901697 0,05990736 ! visual learning GO:0008542 36 19 0,000 0,03901697 0,05986915 ! cellular pigmentation GO:0033059 36 19 0,000 0,03901697 0,059831 ! G1 phase GO:0051318 40 19 0,000 0,03901697 0,05979289 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03901697 0,05975483 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03901697 0,05971681 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03901697 0,05967885 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03901697 0,05964093 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03901697 0,05960307 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03901697 0,05956525 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03901697 0,05952748 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03901697 0,05948975 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03901697 0,05945208 ! cilium assembly GO:0042384 37 19 0,000 0,03901697 0,05941445 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03901697 0,05937687 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04102846 0,06239854 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04102846 0,06235912 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04102846 0,06231975 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04102846 0,06228043 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04102846 0,06224116 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04102846 0,06220194 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04102846 0,06216277 ! response to vitamin GO:0033273 31 20 0,000 0,04102846 0,06212365 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04102846 0,06208458 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04102846 0,06204556 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04102846 0,06200659 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04102846 0,06196766 ! response to alkaloid GO:0043279 38 20 0,000 0,04102846 0,06192879 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04102846 0,06188996 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04102846 0,06185118 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04102846 0,06181245 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04102846 0,06177377 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04102846 0,06173514 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04102846 0,06169655 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,04102846 0,06165802 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04102846 0,06161953 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04102846 0,06158109 ! body fluid secretion GO:0007589 31 20 0,000 0,04102846 0,0615427 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04102846 0,06150435 ! peptide secretion GO:0002790 35 20 0,000 0,04102846 0,06146606 ! stem cell differentiation GO:0048863 53 20 0,000 0,04102846 0,06142781 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04102846 0,06138961 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04102846 0,06135145 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04102846 0,06131334 ! sensory perception of pain GO:0019233 30 20 0,000 0,04102846 0,06127529 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04102846 0,06123727 ! diencephalon development GO:0021536 34 20 0,000 0,04102846 0,06119931 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04102846 0,06116139 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04102846 0,06112352 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04102846 0,0610857 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04102846 0,06104792 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04102846 0,06101019 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04102846 0,0609725 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04102846 0,06093487 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04102846 0,06089728 ! regulation of glucose import GO:0046324 29 20 0,000 0,04102846 0,06085973 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04102846 0,06082223 ! actin filament-based movement GO:0030048 43 20 0,000 0,04102846 0,06078478 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04102846 0,06074738 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04102846 0,06071002 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04102846 0,0606727 ! negative regulation of translation GO:0017148 29 20 0,000 0,04102846 0,06063543 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04102846 0,06059821 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04102846 0,06056103 ! regulation of cell killing GO:0031341 42 21 0,000 0,04303581 0,06348508 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04303581 0,06344618 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04303581 0,06340733 ! hormone secretion GO:0046879 38 21 0,000 0,04303581 0,06336852 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04303581 0,06332977 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04303581 0,06329106 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04303581 0,06325239 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04303581 0,06321378 ! axis specification GO:0009798 38 21 0,000 0,04303581 0,06317521 ! ovarian follicle development GO:0001541 35 21 0,000 0,04303581 0,06313669 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04303581 0,06309821 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04303581 0,06305979 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04303581 0,06302141 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04303581 0,06298307 ! cell aging GO:0007569 44 21 0,000 0,04303581 0,06294478 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04303581 0,06290654 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04303581 0,06286835 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04303581 0,0628302 ! vasodilation GO:0042311 39 21 0,000 0,04303581 0,0627921 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04303581 0,06275404 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,04303581 0,06271603 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04303581 0,06267807 ! oogenesis GO:0048477 36 21 0,000 0,04303581 0,06264015 ! DNA modification GO:0006304 34 21 0,000 0,04303581 0,06260228 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04303581 0,06256445 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04303581 0,06252667 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04303581 0,06248894 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04303581 0,06245125 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04303581 0,0624136 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04303581 0,06237601 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04303581 0,06233845 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04303581 0,06230094 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04303581 0,06226348 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04303581 0,06222606 ! collagen catabolic process GO:0030574 28 21 0,000 0,04303581 0,06218869 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04303581 0,06215136 ! gut development GO:0048565 39 21 0,000 0,04303581 0,06211408 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04503903 0,06496637 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04503903 0,06492744 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04503903 0,06488856 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04503903 0,06484973 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04503903 0,06481095 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04503903 0,06477221 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04503903 0,06473351 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04503903 0,06469487 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04503903 0,06465627 ! regeneration GO:0031099 41 22 0,000 0,04503903 0,06461771 ! keratinization GO:0031424 28 22 0,000 0,04503903 0,0645792 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04503903 0,06454074 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04503903 0,06450232 ! sensory perception of taste GO:0050909 28 22 0,000 0,04503903 0,06446395 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,04503903 0,06442563 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04503903 0,06438735 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04503903 0,06434911 ! vacuolar transport GO:0007034 36 22 0,000 0,04503903 0,06431092 ! lysosome organization GO:0007040 41 22 0,000 0,04503903 0,06427278 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04503903 0,06423468 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04503903 0,06419662 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04503903 0,06415862 ! fucose metabolic process GO:0006004 39 22 0,000 0,04503903 0,06412065 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04503903 0,06408273 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04503903 0,06404486 ! ureteric bud development GO:0001657 43 22 0,000 0,04503903 0,06400703 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04503903 0,06396925 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04503903 0,06393151 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04503903 0,06389381 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04503903 0,06385616 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04503903 0,06381855 ! sarcomere organization GO:0045214 30 22 0,000 0,04503903 0,06378099 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04503903 0,06374347 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04503903 0,063706 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04503903 0,06366857 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04503903 0,06363118 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04503903 0,06359384 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,04503903 0,06355654 ! protein stabilization GO:0050821 39 22 0,000 0,04503903 0,06351929 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,04703812 0,06629977 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04703812 0,06626095 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04703812 0,06622218 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04703812 0,06618345 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04703812 0,06614477 ! gluconeogenesis GO:0006094 33 23 0,000 0,04703812 0,06610614 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04703812 0,06606755 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04703812 0,066029 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04703812 0,0659905 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04703812 0,06595204 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04703812 0,06591363 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04703812 0,06587527 ! visual behavior GO:0007632 42 23 0,000 0,04703812 0,06583694 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04703812 0,06579867 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04703812 0,06576043 ! response to ethanol GO:0045471 46 23 0,000 0,04703812 0,06572225 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04703812 0,0656841 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04703812 0,065646 ! peroxisome organization GO:0007031 37 23 0,000 0,04703812 0,06560795 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04703812 0,06556993 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04703812 0,06553197 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04703812 0,06549404 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04703812 0,06545616 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,04703812 0,06541833 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04703812 0,06538054 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04703812 0,06534279 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04703812 0,06530508 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04703812 0,06526742 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04703812 0,0652298 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04703812 0,06519223 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04703812 0,0651547 ! fatty acid transport GO:0015908 44 23 0,000 0,04703812 0,06511721 ! platelet activation GO:0030168 37 23 0,000 0,04703812 0,06507976 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04703812 0,06504236 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04703812 0,065005 ! hormone transport GO:0009914 40 23 0,000 0,04703812 0,06496769 ! cell-cell recognition GO:0009988 25 23 0,000 0,04703812 0,06493041 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04703812 0,06489318 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04703812 0,06485599 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04703812 0,06481885 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04703812 0,06478174 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04703812 0,06474468 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04903309 0,06745203 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,04903309 0,06741349 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04903309 0,06737499 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,04903309 0,06733653 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04903309 0,06729812 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04903309 0,06725975 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04903309 0,06722143 ! vesicle docking GO:0048278 47 24 0,000 0,04903309 0,06718315 ! spinal cord development GO:0021510 47 24 0,000 0,04903309 0,06714491 ! vacuole organization GO:0007033 43 24 0,000 0,04903309 0,06710671 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04903309 0,06706856 ! digestive system process GO:0022600 39 24 0,000 0,04903309 0,06703046 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04903309 0,06699239 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04903309 0,06695437 ! regulation of behavior GO:0050795 43 24 0,000 0,04903309 0,06691639 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04903309 0,06687846 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04903309 0,06684057 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04903309 0,06680272 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,04903309 0,06676491 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04903309 0,06672715 ! membrane depolarization GO:0051899 39 24 0,000 0,04903309 0,06668943 ! pallium development GO:0021543 49 24 0,000 0,04903309 0,06665175 ! pentose metabolic process GO:0019321 35 24 0,000 0,04903309 0,06661412 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,04903309 0,06657653 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04903309 0,06653898 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04903309 0,06650147 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04903309 0,066464 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04903309 0,06642658 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04903309 0,0663892 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04903309 0,06635186 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04903309 0,06631456 ! regulation of amine transport GO:0051952 40 24 0,000 0,04903309 0,06627731 ! protein tetramerization GO:0051262 52 24 0,000 0,04903309 0,06624009 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05102394 0,06889091 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,05102394 0,06885228 ! myelination GO:0042552 45 25 0,000 0,05102394 0,06881368 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05102394 0,06877513 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05102394 0,06873662 ! phototransduction GO:0007602 33 25 0,000 0,05102394 0,06869816 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05102394 0,06865974 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,05102394 0,06862136 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,05102394 0,06858302 ! sperm motility GO:0030317 31 25 0,000 0,05102394 0,06854473 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05102394 0,06850648 ! receptor metabolic process GO:0043112 46 25 0,000 0,05102394 0,06846827 ! chromosome condensation GO:0030261 45 25 0,000 0,05102394 0,06843011 ! response to starvation GO:0042594 42 25 0,000 0,05102394 0,06839198 ! neural crest cell development GO:0014032 54 25 0,000 0,05102394 0,0683539 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05102394 0,06831587 ! negative regulation of cell development GO:0010721 73 25 0,000 0,05102394 0,06827787 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05102394 0,06823992 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05102394 0,06820201 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05102394 0,06816414 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05102394 0,06812631 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,05102394 0,06808852 ! immunoglobulin production GO:0002377 55 25 0,000 0,05102394 0,06805078 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05102394 0,06801308 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05102394 0,06797542 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05102394 0,0679378 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05102394 0,06790023 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05102394 0,06786269 ! telomere organization GO:0032200 43 25 0,000 0,05102394 0,0678252 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05102394 0,06778775 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05102394 0,06775034 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0530107 0,07034956 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,0530107 0,07031078 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,0530107 0,07027204 ! initiation of viral infection GO:0019059 57 26 0,000 0,0530107 0,07023334 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0530107 0,07019469 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0530107 0,07015608 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,0530107 0,07011751 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,0530107 0,07007898 ! molting cycle process GO:0022404 50 26 0,000 0,0530107 0,0700405 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,0530107 0,07000206 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,0530107 0,06996366 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,0530107 0,0699253 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,0530107 0,06988698 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,0530107 0,06984871 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,0530107 0,06981048 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0530107 0,06977229 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,0530107 0,06973414 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0530107 0,06969604 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0530107 0,06965797 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0530107 0,06961995 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,0530107 0,06958197 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,0530107 0,06954403 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0530107 0,06950613 ! blastocyst development GO:0001824 49 26 0,000 0,0530107 0,06946827 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0530107 0,06943046 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,0530107 0,06939268 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,0530107 0,06935495 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,05499336 0,0719098 ! neuron fate commitment GO:0048663 48 27 0,000 0,05499336 0,07187074 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05499336 0,07183172 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05499336 0,07179275 ! iron ion transport GO:0006826 59 27 0,000 0,05499336 0,07175382 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,05499336 0,07171492 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05499336 0,07167608 ! protein amino acid acylation GO:0043543 55 27 0,000 0,05499336 0,07163727 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05499336 0,0715985 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05499336 0,07155978 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05499336 0,0715211 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,05499336 0,07148246 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05499336 0,07144386 ! autophagy GO:0006914 41 27 0,000 0,05499336 0,07140531 ! male gonad development GO:0008584 44 27 0,000 0,05499336 0,07136679 ! response to toxin GO:0009636 47 27 0,000 0,05499336 0,07132832 ! primary neural tube formation GO:0014020 51 27 0,000 0,05499336 0,07128989 ! base-excision repair GO:0006284 41 27 0,000 0,05499336 0,0712515 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05499336 0,07121315 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05499336 0,07117484 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05499336 0,07113658 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05499336 0,07109835 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05499336 0,07106017 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05499336 0,07102203 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05499336 0,07098392 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05499336 0,07094586 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05697194 0,073459 ! circadian rhythm GO:0007623 50 28 0,000 0,05697194 0,07341965 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05697194 0,07338035 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05697194 0,07334109 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05697194 0,07330187 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05697194 0,07326269 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05697194 0,07322355 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05697194 0,07318446 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05697194 0,07314541 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05697194 0,0731064 ! synaptogenesis GO:0007416 42 28 0,000 0,05697194 0,07306743 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05697194 0,0730285 ! lipid oxidation GO:0034440 43 28 0,000 0,05697194 0,07298961 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05697194 0,07295077 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05697194 0,07291196 ! translational initiation GO:0006413 65 29 0,000 0,05894644 0,0753988 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,05894644 0,07535874 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,05894644 0,07531872 ! regulation of pH GO:0006885 43 29 0,000 0,05894644 0,07527874 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,05894644 0,0752388 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,05894644 0,07519891 ! catechol metabolic process GO:0009712 54 29 0,000 0,05894644 0,07515906 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,05894644 0,07511925 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,05894644 0,07507948 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,05894644 0,07503976 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,05894644 0,07500008 ! cell fate determination GO:0001709 60 29 0,000 0,05894644 0,07496044 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,05894644 0,07492084 ! detection of light stimulus GO:0009583 38 29 0,000 0,05894644 0,07488128 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,05894644 0,07484176 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,05894644 0,07480229 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,05894644 0,07476286 ! tissue homeostasis GO:0001894 48 29 0,000 0,05894644 0,07472347 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,05894644 0,07468412 ! phenol metabolic process GO:0018958 55 30 0,000 0,06091688 0,07714 ! zinc ion transport GO:0006829 45 30 0,000 0,06091688 0,07709942 ! membrane docking GO:0022406 61 30 0,000 0,06091688 0,07705889 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06091688 0,07701839 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06091688 0,07697794 ! acute-phase response GO:0006953 49 30 0,000 0,06091688 0,07693754 ! myofibril assembly GO:0030239 47 30 0,000 0,06091688 0,07689717 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,06091688 0,07685685 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06091688 0,07681656 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06091688 0,07677633 ! phospholipid transport GO:0015914 51 30 0,000 0,06091688 0,07673613 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06091688 0,07669597 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06091688 0,07665586 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06091688 0,07661579 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06091688 0,07657576 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06091688 0,07653577 ! eye morphogenesis GO:0048592 60 30 0,000 0,06091688 0,07649583 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06091688 0,07645592 ! response to heat GO:0009408 50 30 0,000 0,06091688 0,07641606 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06288325 0,07884163 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06288325 0,07880057 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06288325 0,07875955 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06288325 0,07871857 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06288325 0,07867764 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06288325 0,07863674 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06288325 0,07859589 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06288325 0,07855509 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06288325 0,07851432 ! ovulation cycle process GO:0022602 49 31 0,000 0,06288325 0,0784736 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06288325 0,07843292 ! peptide transport GO:0015833 55 31 0,000 0,06288325 0,07839228 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06288325 0,07835168 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06288325 0,07831113 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06288325 0,07827061 ! natural killer cell activation GO:0030101 45 31 0,000 0,06288325 0,07823014 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06288325 0,07818971 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06288325 0,07814933 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06288325 0,07810898 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06288325 0,07806868 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06288325 0,07802841 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06484557 0,08042188 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06484557 0,08038044 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06484557 0,08033905 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06484557 0,0802977 ! cholesterol transport GO:0030301 56 32 0,000 0,06484557 0,0802564 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06484557 0,08021514 ! spliceosome assembly GO:0000245 67 32 0,000 0,06484557 0,08017391 ! spindle organization GO:0007051 46 32 0,000 0,06484557 0,08013274 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06484557 0,0800916 ! metanephros development GO:0001656 74 32 0,000 0,06484557 0,08005051 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06484557 0,08000946 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06484557 0,07996845 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06484557 0,07992748 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06484557 0,07988655 ! muscle cell development GO:0055001 49 32 0,000 0,06484557 0,07984567 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06484557 0,07980483 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06484557 0,07976403 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06484557 0,07972327 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,06484557 0,07968255 ! ovulation cycle GO:0042698 51 32 0,000 0,06484557 0,07964188 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06484557 0,07960124 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06484557 0,07956065 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06484557 0,0795201 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,06484557 0,07947959 ! gene silencing GO:0016458 65 32 0,000 0,06484557 0,07943912 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06680384 0,08179646 ! post-embryonic development GO:0009791 69 33 0,000 0,06680384 0,08175486 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,06680384 0,08171329 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06680384 0,08167177 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,06680384 0,08163029 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06680384 0,08158886 ! cell fate specification GO:0001708 52 33 0,000 0,06680384 0,08154746 ! sterol transport GO:0015918 57 33 0,000 0,06680384 0,08150611 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,06680384 0,0814648 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06680384 0,08142353 ! adult locomotory behavior GO:0008344 59 33 0,000 0,06680384 0,0813823 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,06680384 0,08134112 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06680384 0,08129997 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,06875808 0,08363597 ! glial cell differentiation GO:0010001 63 34 0,000 0,06875808 0,08359371 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,06875808 0,08355149 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,06875808 0,08350931 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,06875808 0,08346718 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,06875808 0,08342509 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,06875808 0,08338304 ! mismatch repair GO:0006298 46 34 0,000 0,06875808 0,08334103 ! spermatid development GO:0007286 63 34 0,000 0,06875808 0,08329907 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,06875808 0,08325715 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,06875808 0,08321527 ! placenta development GO:0001890 53 34 0,000 0,06875808 0,08317343 ! regulation of muscle development GO:0048634 70 35 0,000 0,0707083 0,08548953 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0707083 0,08544659 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0707083 0,0854037 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0707083 0,08536084 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0707083 0,08531804 ! odontogenesis GO:0042476 66 35 0,000 0,0707083 0,08527527 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0707083 0,08523255 ! female gonad development GO:0008585 58 35 0,000 0,0707083 0,08518987 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0707083 0,08514723 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0707083 0,08510463 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,0707083 0,08506208 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0707083 0,08501957 ! cytokine production GO:0001816 59 35 0,000 0,0707083 0,0849771 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,0707083 0,08493468 ! neural tube formation GO:0001841 67 35 0,000 0,0707083 0,0848923 ! vesicle localization GO:0051648 64 35 0,000 0,0707083 0,08484996 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07265449 0,08714193 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07265449 0,08709851 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07265449 0,08705513 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07265449 0,0870118 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07265449 0,08696851 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07265449 0,08692526 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07265449 0,08688206 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07265449 0,0868389 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07265449 0,08679578 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,07265449 0,08675271 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07265449 0,08670967 ! aerobic respiration GO:0009060 55 36 0,000 0,07265449 0,08666668 ! embryonic organ development GO:0048568 57 36 0,000 0,07265449 0,08662374 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07265449 0,08658083 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07265449 0,08653797 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07459667 0,08880732 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07459667 0,0887634 ! meiosis I GO:0007127 65 37 0,000 0,07459667 0,08871952 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07459667 0,08867569 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07459667 0,0886319 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07459667 0,08858815 ! organic anion transport GO:0015711 68 37 0,000 0,07459667 0,08854445 ! tissue remodeling GO:0048771 76 37 0,000 0,07459667 0,08850078 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07459667 0,08845717 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07459667 0,08841359 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07459667 0,08837006 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07459667 0,08832657 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07459667 0,08828312 ! pigment metabolic process GO:0042440 80 37 0,000 0,07459667 0,08823972 ! spermatid differentiation GO:0048515 66 37 0,000 0,07459667 0,08819636 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,07653485 0,09044344 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,07653485 0,09039904 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,07653485 0,09035469 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,07653485 0,09031037 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,07653485 0,0902661 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,07653485 0,09022188 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,07653485 0,09017769 ! lipid homeostasis GO:0055088 67 38 0,000 0,07653485 0,09013355 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,07653485 0,09008946 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,07653485 0,0900454 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,07653485 0,09000139 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,07653485 0,08995742 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,07653485 0,0899135 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,07653485 0,08986962 ! mRNA catabolic process GO:0006402 71 39 0,000 0,07846903 0,09209585 ! learning GO:0007612 77 39 0,000 0,07846903 0,09205095 ! ear morphogenesis GO:0042471 60 39 0,000 0,07846903 0,09200609 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,07846903 0,09196127 ! segmentation GO:0035282 67 39 0,000 0,07846903 0,0919165 ! ion transmembrane transport GO:0034220 66 39 0,000 0,07846903 0,09187177 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,07846903 0,09182709 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,07846903 0,09178245 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,07846903 0,09173785 ! RNA modification GO:0009451 57 39 0,000 0,07846903 0,09169329 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,07846903 0,09164878 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08039923 0,09385762 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08039923 0,0938121 ! feeding behavior GO:0007631 59 40 0,000 0,08039923 0,09376662 ! negative regulation of binding GO:0051100 72 40 0,000 0,08039923 0,0937212 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08039923 0,09367581 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08039923 0,09363047 ! maintenance of protein location GO:0045185 91 40 0,000 0,08039923 0,09358517 ! cytokinesis GO:0000910 72 40 0,000 0,08039923 0,09353992 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08232545 0,09573467 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08232545 0,09568842 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08232545 0,09564221 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08232545 0,09559606 ! gliogenesis GO:0042063 88 41 0,000 0,08232545 0,09554994 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08232545 0,09550387 ! T cell differentiation GO:0030217 81 41 0,000 0,08232545 0,09545784 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08232545 0,09541186 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,08232545 0,09536593 ! female gamete generation GO:0007292 61 41 0,000 0,08232545 0,09532003 ! polyol metabolic process GO:0019751 66 41 0,000 0,08232545 0,09527418 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08232545 0,09522838 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08424769 0,09740507 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08424769 0,09735829 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08424769 0,09731155 ! regulation of tube size GO:0035150 71 42 0,000 0,08424769 0,09726485 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08424769 0,0972182 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08424769 0,0971716 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08424769 0,09712504 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08424769 0,09707852 ! neuron migration GO:0001764 79 42 0,000 0,08424769 0,09703205 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08424769 0,09698562 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,08424769 0,09693924 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,08616598 0,09909911 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,08616598 0,09905177 ! glucose transport GO:0015758 65 43 0,000 0,08616598 0,09900446 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,08616598 0,0989572 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,08616598 0,09890999 ! neural tube development GO:0021915 77 43 0,000 0,08616598 0,09886283 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,08616598 0,0988157 ! striated muscle contraction GO:0006941 77 43 0,000 0,08616598 0,09876863 ! phagocytosis GO:0006909 90 43 0,000 0,08616598 0,09872159 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,08616598 0,0986746 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,08808031 0,10081885 ! hexose transport GO:0008645 67 44 0,000 0,08808031 0,10077091 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,08808031 0,10072301 ! male sex differentiation GO:0046661 76 44 0,000 0,08808031 0,10067516 ! double-strand break repair GO:0006302 81 44 0,000 0,08808031 0,10062736 ! biopolymer methylation GO:0043414 84 44 0,000 0,08808031 0,1005796 ! B cell differentiation GO:0030183 107 44 0,000 0,08808031 0,10053189 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,08808031 0,10048422 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,08808031 0,1004366 ! developmental growth GO:0048589 82 44 0,000 0,08808031 0,10038902 ! maintenance of location in cell GO:0051651 97 44 0,000 0,08808031 0,10034149 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,08999069 0,10246929 ! glycolysis GO:0006096 65 45 0,000 0,08999069 0,10242081 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,08999069 0,10237239 ! leukocyte migration GO:0050900 68 45 0,000 0,08999069 0,10232401 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,08999069 0,10227567 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,08999069 0,10222739 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,08999069 0,10217914 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,08999069 0,10213094 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,08999069 0,10208279 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,08999069 0,10203469 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,08999069 0,10198662 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,08999069 0,10193861 ! cell growth GO:0016049 84 45 0,000 0,08999069 0,10189064 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,09189713 0,10400024 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09189713 0,10395134 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,09189713 0,10390249 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09189713 0,10385369 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,09189713 0,10380493 ! pigmentation GO:0043473 100 46 0,000 0,09189713 0,10375622 ! positive regulation of defense response GO:0031349 76 47 0,000 0,09379965 0,10585457 ! response to calcium ion GO:0051592 81 47 0,000 0,09379965 0,10580495 ! endosome transport GO:0016197 108 47 0,000 0,09379965 0,10575537 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,09379965 0,10570583 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,09379965 0,10565635 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,09379965 0,1056069 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,09379965 0,10555751 ! JNK cascade GO:0007254 91 47 0,000 0,09379965 0,10550816 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,09379965 0,10545886 ! methylation GO:0032259 90 47 0,000 0,09379965 0,1054096 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,09569824 0,10749298 ! mitochondrial transport GO:0006839 82 48 0,000 0,09569824 0,10744282 ! Notch signaling pathway GO:0007219 96 48 0,000 0,09569824 0,10739271 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,09569824 0,10734264 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,09569824 0,10729262 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,09569824 0,10724265 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,09569824 0,10719272 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,09569824 0,10714284 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,09569824 0,10709301 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,09569824 0,10704322 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,09759291 0,10911178 ! regulation of action potential GO:0001508 95 49 0,000 0,09759291 0,1090611 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,09759291 0,10901047 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,09759291 0,10895989 ! regulation of ion transport GO:0043269 77 49 0,000 0,09759291 0,10890935 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,09759291 0,10885886 ! peptide metabolic process GO:0006518 76 49 0,000 0,09759291 0,10880841 ! response to temperature stimulus GO:0009266 76 49 0,000 0,09759291 0,10875801 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,09759291 0,10870766 ! endocrine system development GO:0035270 104 49 0,000 0,09759291 0,10865736 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,09759291 0,1086071 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,09759291 0,10855689 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,09759291 0,10850673 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,09948368 0,11055785 ! neuromuscular process GO:0050905 99 50 0,000 0,09948368 0,11050681 ! inner ear development GO:0048839 79 50 0,000 0,09948368 0,11045581 ! histone modification GO:0016570 91 50 0,000 0,09948368 0,11040486 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,09948368 0,11035396 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,09948368 0,11030311 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,09948368 0,1102523 ! positive regulation of binding GO:0051099 78 51 0,000 0,10137055 0,11229169 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10137055 0,11224002 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10137055 0,11218839 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10137055 0,11213681 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10137055 0,11208527 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10137055 0,11203379 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10137055 0,11198235 ! vesicle organization GO:0016050 107 51 0,000 0,10137055 0,11193096 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,10137055 0,11187961 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,10137055 0,11182831 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10137055 0,11177706 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,10325353 0,11380119 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,10325353 0,11374909 ! membrane fusion GO:0006944 110 52 0,000 0,10325353 0,11369703 ! positive regulation of growth GO:0045927 90 52 0,000 0,10325353 0,11364501 ! covalent chromatin modification GO:0016569 101 52 0,000 0,10325353 0,11359305 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,10325353 0,11354113 ! amino acid activation GO:0043038 92 52 0,000 0,10325353 0,11348927 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,10325353 0,11343744 ! synapse organization GO:0050808 85 52 0,000 0,10325353 0,11338567 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10513263 0,11539649 ! RNA catabolic process GO:0006401 93 53 0,000 0,10513263 0,11534387 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10513263 0,1152913 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,10513263 0,11523877 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,10513263 0,1151863 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,10513263 0,11513387 ! cell maturation GO:0048469 100 53 0,000 0,10513263 0,11508149 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,10513263 0,11502915 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,10513263 0,11497687 ! response to UV GO:0009411 104 53 0,000 0,10513263 0,11492463 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,10700785 0,11692138 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,10700785 0,11686831 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,10700785 0,11681529 ! cell recognition GO:0008037 85 54 0,000 0,10700785 0,11676231 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,10700785 0,11670938 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,10700785 0,1166565 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,10700785 0,11660366 ! chloride transport GO:0006821 90 55 0,000 0,1088792 0,11858912 ! glucose catabolic process GO:0006007 82 55 0,000 0,1088792 0,11853546 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,1088792 0,11848185 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,1088792 0,11842828 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,1088792 0,11837477 ! aging GO:0007568 103 55 0,000 0,1088792 0,1183213 ! heart morphogenesis GO:0003007 97 55 0,000 0,1088792 0,11826789 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,1088792 0,11821452 ! RNA elongation GO:0006354 79 55 0,000 0,1088792 0,11816119 ! nuclear export GO:0051168 97 55 0,000 0,1088792 0,11810792 ! regulation of actin filament length GO:0030832 105 56 0,000 0,1107467 0,12007957 ! sensory perception of smell GO:0007608 80 56 0,000 0,1107467 0,12002548 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,1107467 0,11997143 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,1107467 0,11991744 ! proton transport GO:0015992 94 56 0,000 0,1107467 0,1198635 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,1107467 0,1198096 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,11261034 0,121771 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,11261034 0,1217163 ! maintenance of location GO:0051235 118 57 0,000 0,11261034 0,12166164 ! hydrogen transport GO:0006818 97 58 0,000 0,11447014 0,12361542 ! regulation of endocytosis GO:0030100 91 58 0,000 0,11447014 0,12355996 ! adult behavior GO:0030534 99 58 0,000 0,11447014 0,12350455 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,11447014 0,1234492 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1163261 0,12539454 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,1163261 0,12533838 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1163261 0,12528228 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,1163261 0,12522622 ! establishment of organelle localization GO:0051656 109 59 0,000 0,1163261 0,12517022 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,11817824 0,12710632 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,11817824 0,12704953 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,11817824 0,12699278 ! regulation of heart contraction GO:0008016 110 60 0,000 0,11817824 0,12693609 ! camera-type eye development GO:0043010 116 60 0,000 0,11817824 0,12687945 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,11817824 0,12682285 ! kidney development GO:0001822 122 60 0,000 0,11817824 0,12676631 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12002655 0,12869157 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,12002655 0,12863425 ! tRNA processing GO:0008033 89 61 0,000 0,12002655 0,12857697 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12002655 0,12851975 ! ear development GO:0043583 103 62 0,000 0,12187105 0,13043672 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12187105 0,13037872 ! gonad development GO:0008406 98 62 0,000 0,12187105 0,13032078 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,12187105 0,13026288 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,12371175 0,13217161 ! detection of external stimulus GO:0009581 91 63 0,000 0,12371175 0,13211295 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,12371175 0,13205433 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,12554865 0,13395567 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,12554865 0,1338963 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,12554865 0,13383697 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,12738176 0,13573096 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,12738176 0,13567087 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,12738176 0,13561084 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,12738176 0,13555087 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,12738176 0,13549094 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,12921108 0,13737599 ! extracellular matrix organization GO:0030198 133 66 0,000 0,12921108 0,13731531 ! secondary metabolic process GO:0019748 116 66 0,000 0,12921108 0,13725469 ! developmental maturation GO:0021700 116 66 0,000 0,12921108 0,13719412 ! cell projection assembly GO:0030031 120 66 0,000 0,12921108 0,1371336 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,13103664 0,13900977 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,13103664 0,1389485 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,13103664 0,13888729 ! activation of MAPK activity GO:0000187 115 67 0,000 0,13103664 0,13882613 ! lung development GO:0030324 144 67 0,000 0,13103664 0,13876503 ! chromosome segregation GO:0007059 113 67 0,000 0,13103664 0,13870398 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,13103664 0,13864299 ! hexose catabolic process GO:0019320 104 67 0,000 0,13103664 0,13858204 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,13103664 0,13852116 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,13103664 0,13846032 ! amino acid transport GO:0006865 125 68 0,000 0,13285842 0,14032369 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,13285842 0,14026212 ! regulation of lipase activity GO:0060191 130 68 0,000 0,13285842 0,1402006 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,13467645 0,14205679 ! negative regulation of cell size GO:0045792 134 69 0,000 0,13467645 0,14199454 ! urogenital system development GO:0001655 137 69 0,000 0,13467645 0,14193234 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,13467645 0,1418702 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,13467645 0,14180812 ! antigen processing and presentation GO:0019882 104 69 0,000 0,13467645 0,14174608 ! appendage morphogenesis GO:0035107 135 70 0,000 0,13649073 0,14359278 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,13649073 0,14353002 ! amine catabolic process GO:0009310 117 71 0,000 0,13830126 0,1453704 ! reproductive structure development GO:0048608 113 71 0,000 0,13830126 0,14530691 ! appendage development GO:0048736 136 71 0,000 0,13830126 0,14524349 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,13830126 0,14518012 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,13830126 0,14511681 ! regulation of immune effector process GO:0002697 137 71 0,000 0,13830126 0,14505355 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,14010806 0,14688453 ! carbohydrate transport GO:0008643 110 72 0,000 0,14010806 0,14682055 ! respiratory system development GO:0060541 153 72 0,000 0,14010806 0,14675663 ! learning or memory GO:0007611 147 73 0,000 0,14191113 0,14858058 ! regulation of blood pressure GO:0008217 125 73 0,000 0,14191113 0,14851595 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,14191113 0,14845138 ! axon guidance GO:0007411 139 73 0,000 0,14191113 0,14838686 ! fertilization GO:0009566 90 73 0,000 0,14191113 0,1483224 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,14371047 0,15013782 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,14371047 0,15007266 ! neurotransmitter transport GO:0006836 123 74 0,000 0,14371047 0,15000755 ! meiosis GO:0007126 121 74 0,000 0,14371047 0,1499425 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,14371047 0,1498775 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,14371047 0,14981257 ! eye development GO:0001654 143 74 0,000 0,14371047 0,14974768 ! organelle localization GO:0051640 136 74 0,000 0,14371047 0,14968286 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,14550611 0,15148754 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,14550611 0,15142201 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,14550611 0,15135655 ! meiotic cell cycle GO:0051321 122 75 0,000 0,14550611 0,15129114 ! rhythmic process GO:0048511 128 75 0,000 0,14550611 0,15122579 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,14550611 0,15116049 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,14729804 0,15295601 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,14729804 0,15289002 ! defense response to bacterium GO:0042742 89 76 0,000 0,14729804 0,1528241 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,14729804 0,15275822 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,14729804 0,15269241 ! regulation of catabolic process GO:0009894 161 76 0,000 0,14729804 0,15262665 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,14908627 0,15441307 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,14908627 0,15434663 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,14908627 0,15428024 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,15087081 0,15605983 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,15087081 0,15599276 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,15087081 0,15592576 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,15265166 0,15769854 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,15265166 0,15763086 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,15265166 0,15756324 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,15265166 0,15749567 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,15442884 0,15926095 ! response to metal ion GO:0010038 140 80 0,000 0,15442884 0,15919272 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,15442884 0,15912454 ! protein import into nucleus GO:0006606 158 80 0,000 0,15442884 0,15905642 ! inorganic anion transport GO:0015698 138 80 0,000 0,15442884 0,15898836 ! T cell activation GO:0042110 168 81 0,000 0,15620236 0,16074545 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,15620236 0,16067673 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,15620236 0,16060806 ! digestion GO:0007586 112 81 0,000 0,15620236 0,16053946 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,15620236 0,16047091 ! nuclear import GO:0051170 161 81 0,000 0,15620236 0,16040242 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,15620236 0,16033399 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,15797221 0,16208151 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,15797221 0,16201242 ! response to drug GO:0042493 143 82 0,000 0,15797221 0,16194339 ! response to nutrient GO:0007584 125 82 0,000 0,15797221 0,16187442 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,15797221 0,1618055 ! response to oxygen levels GO:0070482 176 83 0,000 0,1597384 0,16354494 ! regulation of lyase activity GO:0051339 160 83 0,000 0,1597384 0,16347537 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,16150096 0,16520889 ! negative regulation of transport GO:0051051 153 84 0,000 0,16150096 0,16513867 ! negative regulation of growth GO:0045926 155 84 0,000 0,16150096 0,16506852 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,16150096 0,16499843 ! response to unfolded protein GO:0006986 131 85 0,000 0,16325987 0,16672464 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,16325987 0,1666539 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,16325987 0,16658323 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,16501515 0,16830286 ! response to inorganic substance GO:0010035 153 86 0,000 0,16501515 0,16823155 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,16501515 0,16816029 ! tube morphogenesis GO:0035239 176 86 0,000 0,16501515 0,1680891 ! mitochondrion organization GO:0007005 148 86 0,000 0,16501515 0,16801797 ! alcohol catabolic process GO:0046164 130 86 0,000 0,16501515 0,16794689 ! amine transport GO:0015837 155 86 0,000 0,16501515 0,16787588 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,16676681 0,1695862 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,16676681 0,16951455 ! protein localization in nucleus GO:0034504 176 87 0,000 0,16676681 0,16944297 ! cellular respiration GO:0045333 135 88 0,000 0,16851485 0,17114678 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,16851485 0,17107457 ! regulation of DNA binding GO:0051101 155 88 0,000 0,16851485 0,17100242 ! regulation of neurological system process GO:0031644 148 88 0,000 0,16851485 0,17093033 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,16851485 0,17085829 ! cellular defense response GO:0006968 114 89 0,000 0,17025928 0,17255427 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,17025928 0,17248162 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,17025928 0,17240902 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,17200011 0,17409856 ! sex differentiation GO:0007548 145 90 0,000 0,17200011 0,17402535 ! sterol metabolic process GO:0016125 152 91 0,000 0,17373735 0,17570915 ! response to protein stimulus GO:0051789 149 91 0,000 0,17373735 0,17563532 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,17373735 0,17556156 ! regulation of defense response GO:0031347 149 92 0,000 0,175471 0,17723897 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,175471 0,17716459 ! vitamin metabolic process GO:0006766 139 92 0,000 0,175471 0,17709028 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,17720107 0,17876133 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,17720107 0,17868641 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,17720107 0,17861155 ! regulation of membrane potential GO:0042391 164 93 0,000 0,17720107 0,17853676 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,17720107 0,17846202 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,17892757 0,18012541 ! female pregnancy GO:0007565 164 94 0,000 0,17892757 0,18005007 ! regulation of T cell activation GO:0050863 158 94 0,000 0,17892757 0,1799748 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,1806505 0,18163188 ! forebrain development GO:0030900 188 95 0,000 0,1806505 0,18155601 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,1806505 0,18148021 ! leukocyte differentiation GO:0002521 202 96 0,000 0,18236987 0,18313101 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,18236987 0,18305461 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! detection of stimulus GO:0051606 151 96 0,000 0,18236987 0,18297828 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,18408569 0,18462283 ! protein ubiquitination GO:0016567 217 97 0,000 0,18408569 0,18454591 ! hormone metabolic process GO:0042445 157 97 0,000 0,18408569 0,18446904 ! response to virus GO:0009615 160 98 0,000 0,18579797 0,18610738 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,18579797 0,18602993 ! interphase GO:0051325 213 98 0,000 0,18579797 0,18595254 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,18579797 0,18587523 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,18750671 0,18750671