pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1234-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 5,000 1,353E-14 3,306E-11 ! myoblast cell fate commitment GO:0048625 18 6 2,000 1,163E-07 1,42E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 3,247E-07 2,644E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 3,247E-07 1,983E-04 ! BMP signaling pathway GO:0030509 71 32 3,000 3,523E-07 1,721E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 4,865E-07 1,981E-04 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 9,53E-07 3,326E-04 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 3,000 1,191E-06 3,637E-04 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 1,269E-06 3,445E-04 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 2,614E-06 6,387E-04 ! myoblast differentiation GO:0045445 50 17 2,000 3,897E-06 8,655E-04 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 5,539E-06 1,128E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 6,508E-06 1,223E-03 ! pancreas development GO:0031016 40 20 2,000 6,508E-06 1,136E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 3,000 7,158E-06 1,166E-03 ! negative regulation of ligase activity GO:0051352 116 68 3,000 7,595E-06 1,16E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 3,000 7,595E-06 1,091E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 3,000 8,051E-06 1,093E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 8,768E-06 1,127E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 3,000 9,542E-06 1,166E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 3,000 9,542E-06 1,11E-03 ! cell-matrix adhesion GO:0007160 181 76 3,000 1,183E-05 1,314E-03 ! positive regulation of ligase activity GO:0051351 130 77 3,000 1,247E-05 1,324E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 1,304E-05 1,328E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 3,000 1,38E-05 1,349E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 3,000 1,451E-05 1,363E-03 ! cell-substrate adhesion GO:0031589 189 82 3,000 1,6E-05 1,448E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 1,654E-05 1,444E-03 ! regulation of ligase activity GO:0051340 147 84 3,000 1,76E-05 1,483E-03 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,845E-05 1,502E-03 ! fat cell differentiation GO:0045444 57 28 2,000 1,851E-05 1,458E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 2,061E-05 1,574E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 3,000 2,631E-05 1,948E-03 GO:0010498|proteasomal protein catabolic process, ! androgen receptor signaling pathway GO:0030521 81 37 2,000 4,338E-05 3,117E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 4,704E-05 3,283E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 4,916E-05 3,336E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! interaction with symbiont GO:0051702 14 6 1,000 4,916E-05 3,246E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 5,089E-05 3,272E-03 GO:0042593|glucose homeostasis, ! regulation of hormone secretion GO:0046883 69 41 2,000 5,92E-05 3,709E-03 ! mesenchymal cell development GO:0014031 94 41 2,000 5,92E-05 3,616E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 86 42 2,000 6,367E-05 3,794E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,874E-05 3,999E-03 ! transcription from RNA polymerase I promoter GO:0006360 14 7 1,000 6,874E-05 3,906E-03 ! transcription termination GO:0006353 14 7 1,000 6,874E-05 3,817E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 8,376E-05 4,547E-03 ! positive regulation of protein transport GO:0051222 80 46 2,000 8,376E-05 4,448E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 8,935E-05 4,644E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 9,155E-05 4,659E-03 ! ER overload response GO:0006983 13 8 1,000 9,155E-05 4,564E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 1,176E-04 5,744E-03 ! chromatin remodeling GO:0006338 122 53 2,000 1,281E-04 6,135E-03 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 1,468E-04 6,896E-03 ! midbrain development GO:0030901 14 10 1,000 1,468E-04 6,766E-03 ! skeletal muscle fiber development GO:0048741 130 56 2,000 1,51E-04 6,83E-03 ! muscle fiber development GO:0048747 131 57 2,000 1,591E-04 7,069E-03 ! regulation of intracellular transport GO:0032386 108 57 2,000 1,591E-04 6,943E-03 ! positive regulation of secretion GO:0051047 110 61 2,000 1,947E-04 8,346E-03 ! protein complex disassembly GO:0043241 28 12 1,000 2,148E-04 9,046E-03 GO:0043624|cellular protein complex disassembly, ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,148E-04 8,893E-03 ! focal adhesion formation GO:0048041 37 12 1,000 2,148E-04 8,745E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 2,246E-04 8,993E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 2,46E-04 9,693E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 3,052E-04 0,01183669 ! cell killing GO:0001906 32 15 1,000 3,405E-04 0,01299676 ! regulation of caspase activity GO:0043281 136 74 2,000 3,449E-04 0,01296108 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 3,876E-04 0,014348 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,887E-04 0,01417163 ! complement activation, alternative pathway GO:0006957 19 17 1,000 4,4E-04 0,01580631 ! muscle cell differentiation GO:0042692 178 81 2,000 4,498E-04 0,01592428 ! regulation of peptidase activity GO:0052547 150 82 2,000 4,662E-04 0,01627167 ! cell-substrate junction assembly GO:0007044 56 18 1,000 4,944E-04 0,01701066 ! regulation of protein transport GO:0051223 165 87 2,000 5,544E-04 0,01881125 GO:0070201|regulation of establishment of protein localization, ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 6,125E-04 0,02049717 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 6,125E-04 0,02022018 ! actin filament bundle formation GO:0051017 47 20 1,000 6,125E-04 0,01995058 ! lipid phosphorylation GO:0046834 43 21 1,000 6,762E-04 0,02173485 ! cellular macromolecular complex disassembly GO:0034623 44 21 1,000 6,762E-04 0,02145258 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 6,762E-04 0,02117754 ! cytolysis GO:0019835 27 22 1,000 7,429E-04 0,02297331 ! peptidyl-serine modification GO:0018209 50 22 1,000 7,429E-04 0,02268614 ! regulation of protein localization GO:0032880 188 97 2,000 7,612E-04 0,02295846 ! viral genome replication GO:0019079 44 23 1,000 8,127E-04 0,02421214 ! skeletal muscle tissue development GO:0007519 223 100 2,000 8,316E-04 0,0244765 GO:0060538|skeletal muscle organ development, ! negative regulation of DNA replication GO:0008156 45 25 1,000 9,614E-04 0,02796045 ! interaction with host GO:0051701 66 25 1,000 9,614E-04 0,02763151 ! macromolecular complex disassembly GO:0032984 54 26 1,000 1,04E-03 0,0295512 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,04E-03 0,02921153 ! osteoblast differentiation GO:0001649 63 26 1,000 1,04E-03 0,02887958 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,04E-03 0,02855509 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,04E-03 0,02823781 ! embryonic pattern specification GO:0009880 49 27 1,000 1,122E-03 0,03012618 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 1,295E-03 0,03438688 ! complement activation, classical pathway GO:0006958 51 30 1,000 1,386E-03 0,03640401 ! cell junction assembly GO:0034329 85 31 1,000 1,48E-03 0,03845531 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 1,576E-03 0,04053943 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,576E-03 0,04011714 ! mesoderm formation GO:0001707 73 32 1,000 1,576E-03 0,03970357 ! hindbrain development GO:0030902 65 32 1,000 1,576E-03 0,03929843 ! formation of primary germ layer GO:0001704 76 34 1,000 1,779E-03 0,04389593 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 1,779E-03 0,04345697 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 1,884E-03 0,04558067 ! mesoderm morphogenesis GO:0048332 80 35 1,000 1,884E-03 0,0451338 ! cell junction organization GO:0034330 96 37 1,000 2,104E-03 0,04991137 ! glycogen metabolic process GO:0005977 63 38 1,000 2,219E-03 0,05211627 ! glucan metabolic process GO:0044042 64 39 1,000 2,336E-03 0,05434618 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 2,456E-03 0,05660018 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 2,456E-03 0,05607121 ! glycerol ether metabolic process GO:0006662 57 40 1,000 2,456E-03 0,05555203 ! organic ether metabolic process GO:0018904 59 42 1,000 2,704E-03 0,06061551 ! hormone-mediated signaling GO:0009755 84 43 1,000 2,833E-03 0,06292037 ! energy reserve metabolic process GO:0006112 76 44 1,000 2,965E-03 0,06524595 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 3,099E-03 0,06759146 ! cellular component disassembly GO:0022411 89 48 1,000 3,518E-03 0,076063 ! protein homooligomerization GO:0051260 84 49 1,000 3,664E-03 0,07851177 ! activation of caspase activity GO:0006919 95 50 1,000 3,812E-03 0,08097671 ! regulation of ossification GO:0030278 123 50 1,000 3,812E-03 0,08027864 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 3,812E-03 0,07959249 GO:0019724|B cell mediated immunity, ! viral infectious cycle GO:0019058 104 51 1,000 3,963E-03 0,08204266 ! excretion GO:0007588 87 52 1,000 4,116E-03 0,084508 ! negative regulation of cell motion GO:0051271 142 55 1,000 4,594E-03 0,09352247 ! regulation of DNA replication GO:0006275 105 56 1,000 4,758E-03 0,09607184 ! regulation of bone remodeling GO:0046850 143 57 1,000 4,926E-03 0,09863337 ! positive regulation of caspase activity GO:0043280 108 57 1,000 4,926E-03 0,09783147 GO:0010952|positive regulation of peptidase activity, ! positive regulation of cell migration GO:0030335 137 58 1,000 5,096E-03 0,10039038 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 5,096E-03 0,09958725 ! gastrulation GO:0007369 122 58 1,000 5,096E-03 0,09879688 ! regulation of tissue remodeling GO:0034103 146 58 1,000 5,096E-03 0,09801895 ! lipid modification GO:0030258 112 60 1,000 5,443E-03 0,1038926 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 5,621E-03 0,10645671 ! viral reproductive process GO:0022415 132 62 1,000 5,802E-03 0,10903105 ! regulation of mitosis GO:0007088 112 63 1,000 5,985E-03 0,11161522 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 5,985E-03 0,11076965 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 6,171E-03 0,11335009 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 6,171E-03 0,11250419 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 6,359E-03 0,11508087 ! positive regulation of cell motion GO:0051272 157 65 1,000 6,359E-03 0,11423468 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 6,55E-03 0,11680755 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 6,94E-03 0,12286277 ! viral reproduction GO:0016032 142 68 1,000 6,94E-03 0,12197887 ! adaptive immune response GO:0002250 126 68 1,000 6,94E-03 0,12110759 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 7,139E-03 0,12369309 ! negative regulation of kinase activity GO:0033673 145 70 1,000 7,34E-03 0,1262863 ! cell redox homeostasis GO:0045454 114 70 1,000 7,34E-03 0,12540318 ! activation of immune response GO:0002253 120 70 1,000 7,34E-03 0,12453232 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 7,34E-03 0,12367348 ! cAMP-mediated signaling GO:0019933 124 71 1,000 7,544E-03 0,12623854 ! actin filament organization GO:0007015 167 72 1,000 7,751E-03 0,12881101 ! humoral immune response GO:0006959 115 73 1,000 7,96E-03 0,13139058 ! acute inflammatory response GO:0002526 118 74 1,000 8,171E-03 0,13397694 ! negative regulation of transferase activity GO:0051348 155 74 1,000 8,171E-03 0,13308376 ! leukocyte mediated immunity GO:0002443 136 75 1,000 8,385E-03 0,13566538 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 8,821E-03 0,14177394 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 9,111E-03 0,14547389 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 9,111E-03 0,14452925 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 9,111E-03 0,1435968 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,111E-03 0,14267631 ! positive regulation of helicase activity GO:0051096 12 5 0,000 9,111E-03 0,14176755 ! neuron fate determination GO:0048664 7 5 0,000 9,111E-03 0,14087028 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,111E-03 0,13998431 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 9,111E-03 0,1391094 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 9,111E-03 0,13824537 ! polyol transport GO:0015791 12 5 0,000 9,111E-03 0,137392 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,111E-03 0,13654911 ! response to superoxide GO:0000303 10 5 0,000 9,111E-03 0,13571649 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,111E-03 0,13489397 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 9,111E-03 0,13408135 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 9,111E-03 0,13327847 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,111E-03 0,13248515 ! female meiosis GO:0007143 10 5 0,000 9,111E-03 0,13170121 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 9,111E-03 0,1309265 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,111E-03 0,13016085 ! hypothalamus development GO:0021854 9 5 0,000 9,111E-03 0,1294041 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 9,111E-03 0,1286561 ! cobalt ion transport GO:0006824 11 5 0,000 9,111E-03 0,12791669 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 9,111E-03 0,12718574 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 9,111E-03 0,12646309 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,111E-03 0,12574861 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,111E-03 0,12504216 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 9,111E-03 0,1243436 ! embryonic camera-type eye development GO:0031076 12 5 0,000 9,111E-03 0,1236528 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,111E-03 0,12296964 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,111E-03 0,12229398 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 9,111E-03 0,12162571 ! transposition GO:0032196 9 5 0,000 9,111E-03 0,1209647 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 9,111E-03 0,12031084 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 9,111E-03 0,119664 ! negative chemotaxis GO:0050919 16 5 0,000 9,111E-03 0,11902409 ! positive regulation of histone modification GO:0031058 6 5 0,000 9,111E-03 0,11839098 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,111E-03 0,11776457 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 9,111E-03 0,11714476 ! behavioral response to pain GO:0048266 10 5 0,000 9,111E-03 0,11653144 ! clathrin coat assembly GO:0048268 15 5 0,000 9,111E-03 0,1159245 ! Notch receptor processing GO:0007220 11 5 0,000 9,111E-03 0,11532386 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,111E-03 0,11472941 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 9,111E-03 0,11414105 ! micturition GO:0060073 9 5 0,000 9,111E-03 0,1135587 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,111E-03 0,11298226 ! copulation GO:0007620 9 5 0,000 9,111E-03 0,11241164 ! glial cell fate commitment GO:0021781 14 5 0,000 9,111E-03 0,11184676 ! protein maturation by protein folding GO:0022417 14 5 0,000 9,111E-03 0,11128752 ! bioluminescence GO:0008218 9 5 0,000 9,111E-03 0,11073385 ! spermidine metabolic process GO:0008216 7 5 0,000 9,111E-03 0,11018567 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,111E-03 0,10964288 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,111E-03 0,10910541 ! apoptotic cell clearance GO:0043277 23 5 0,000 9,111E-03 0,10857319 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,111E-03 0,10804614 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 9,111E-03 0,10752418 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,111E-03 0,10700723 ! grooming behavior GO:0007625 6 5 0,000 9,111E-03 0,10649524 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 9,111E-03 0,10598812 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,111E-03 0,1054858 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 9,111E-03 0,10498823 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,111E-03 0,10449533 ! response to protozoan GO:0001562 13 5 0,000 9,111E-03 0,10400703 ! positive regulation of glycolysis GO:0045821 13 5 0,000 9,111E-03 0,10352328 ! lymph vessel development GO:0001945 10 5 0,000 9,111E-03 0,103044 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 9,111E-03 0,10256915 ! endochondral ossification GO:0001958 17 5 0,000 9,111E-03 0,10209865 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,111E-03 0,10163244 ! single strand break repair GO:0000012 8 5 0,000 9,111E-03 0,10117048 ! parathyroid gland development GO:0060017 14 5 0,000 9,111E-03 0,10071269 ! anagen GO:0042640 7 5 0,000 9,111E-03 0,10025903 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,111E-03 0,09980944 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,111E-03 0,09936386 ! cytokine secretion GO:0050663 15 5 0,000 9,111E-03 0,09892224 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 9,111E-03 0,09848453 ! ceramide catabolic process GO:0046514 7 5 0,000 9,111E-03 0,09805068 ! skeletal myofibril assembly GO:0014866 12 5 0,000 9,111E-03 0,09762063 ! smooth muscle tissue development GO:0048745 32 5 0,000 9,111E-03 0,09719434 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,111E-03 0,09677176 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,111E-03 0,09635283 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,111E-03 0,09593752 ! cardiac muscle fiber development GO:0048739 12 5 0,000 9,111E-03 0,09552577 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,111E-03 0,09511754 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 9,111E-03 0,09471279 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,111E-03 0,09431146 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 9,111E-03 0,09391352 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,111E-03 0,09351893 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 9,111E-03 0,09312763 ! glycine biosynthetic process GO:0006545 7 5 0,000 9,111E-03 0,0927396 ! microvillus organization GO:0032528 8 5 0,000 9,111E-03 0,09235479 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 9,111E-03 0,09197316 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 9,111E-03 0,09159467 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 9,111E-03 0,09121928 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 9,111E-03 0,09084696 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 9,111E-03 0,09047766 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 9,111E-03 0,09011135 ! polyol catabolic process GO:0046174 9 5 0,000 9,111E-03 0,089748 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 9,111E-03 0,08938757 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 9,111E-03 0,08903002 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 9,111E-03 0,08867532 ! muscle cell migration GO:0014812 8 5 0,000 9,111E-03 0,08832343 ! mitochondrial fission GO:0000266 8 5 0,000 9,111E-03 0,08797433 ! sister chromatid cohesion GO:0007062 15 5 0,000 9,111E-03 0,08762797 ! response to tumor necrosis factor GO:0034612 10 5 0,000 9,111E-03 0,08728433 ! mRNA transcription GO:0009299 10 5 0,000 9,111E-03 0,08694338 ! nerve growth factor processing GO:0032455 9 5 0,000 9,111E-03 0,08660508 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 9,111E-03 0,0862694 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 9,111E-03 0,08593631 ! anaerobic glycolysis GO:0019642 6 5 0,000 9,111E-03 0,08560579 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,111E-03 0,0852778 ! monocyte activation GO:0042117 10 5 0,000 9,111E-03 0,08495231 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,111E-03 0,0846293 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,111E-03 0,08430873 ! response to food GO:0032094 6 5 0,000 9,111E-03 0,08399058 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,111E-03 0,08367483 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,111E-03 0,08336144 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 9,111E-03 0,08305039 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,111E-03 0,08274165 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 9,111E-03 0,0824352 ! forebrain neuron development GO:0021884 13 5 0,000 9,111E-03 0,08213101 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,111E-03 0,08182906 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 9,111E-03 0,08152932 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 9,111E-03 0,08123177 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,111E-03 0,08093638 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,111E-03 0,08064313 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 9,111E-03 0,080352 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,111E-03 0,08006297 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 9,111E-03 0,079776 ! lipid glycosylation GO:0030259 7 5 0,000 9,111E-03 0,07949109 ! nucleobase transport GO:0015851 6 5 0,000 9,111E-03 0,0792082 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,111E-03 0,07892732 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 9,111E-03 0,07864843 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 9,111E-03 0,0783715 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 9,111E-03 0,07809651 ! basic amino acid transport GO:0015802 12 5 0,000 9,111E-03 0,07782344 ! cellular glucose homeostasis GO:0001678 6 5 0,000 9,111E-03 0,07755228 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 9,111E-03 0,077283 ! actin nucleation GO:0045010 11 5 0,000 9,111E-03 0,07701559 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,111E-03 0,07675002 ! depurination GO:0045007 5 5 0,000 9,111E-03 0,07648627 ! depyrimidination GO:0045008 10 5 0,000 9,111E-03 0,07622433 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,111E-03 0,07596418 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,111E-03 0,0757058 ! G2/M transition checkpoint GO:0031576 8 5 0,000 9,111E-03 0,07544917 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,111E-03 0,07519427 ! zinc ion homeostasis GO:0055069 9 5 0,000 9,111E-03 0,07494109 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 9,111E-03 0,07468961 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 9,111E-03 0,07443981 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,111E-03 0,07419168 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,111E-03 0,0739452 ! activated T cell proliferation GO:0050798 16 5 0,000 9,111E-03 0,07370035 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,111E-03 0,07345711 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 9,111E-03 0,07321548 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,111E-03 0,07297542 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,111E-03 0,07273694 ! gamma-delta T cell activation GO:0046629 6 5 0,000 9,111E-03 0,07250002 ! response to arsenic GO:0046685 11 5 0,000 9,111E-03 0,07226463 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 9,111E-03 0,07203076 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 9,111E-03 0,0717984 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 9,111E-03 0,07156754 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 9,111E-03 0,07133816 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 9,111E-03 0,07111024 ! response to mercury ion GO:0046689 8 5 0,000 9,111E-03 0,07088377 ! response to cadmium ion GO:0046686 7 5 0,000 9,111E-03 0,07065874 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 9,111E-03 0,07043514 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 9,111E-03 0,07021295 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 9,111E-03 0,06999215 ! bile acid biosynthetic process GO:0006699 7 5 0,000 9,111E-03 0,06977274 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 9,111E-03 0,0695547 ! ganglioside catabolic process GO:0006689 12 5 0,000 9,111E-03 0,06933802 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,111E-03 0,06912269 ! decidualization GO:0046697 11 5 0,000 9,111E-03 0,06890868 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 9,111E-03 0,068696 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 9,111E-03 0,06848463 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 9,111E-03 0,06827455 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 9,111E-03 0,06806576 ! embryonic cleavage GO:0040016 6 5 0,000 9,111E-03 0,06785825 ! peroxisome fission GO:0016559 5 5 0,000 9,111E-03 0,06765199 ! histone demethylation GO:0016577 13 5 0,000 9,111E-03 0,06744698 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 9,111E-03 0,06724322 ! mitotic recombination GO:0006312 9 5 0,000 9,111E-03 0,06704068 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 9,111E-03 0,06683935 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,111E-03 0,06663924 ! metaphase plate congression GO:0051310 7 5 0,000 9,111E-03 0,06644031 ! regulation of sterol transport GO:0032371 7 5 0,000 9,111E-03 0,06624257 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,111E-03 0,06604601 ! enteric nervous system development GO:0048484 8 5 0,000 9,111E-03 0,06585061 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 9,111E-03 0,06565636 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 9,111E-03 0,06546325 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 9,111E-03 0,06527127 ! muscle cell proliferation GO:0033002 12 5 0,000 9,111E-03 0,06508042 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,111E-03 0,06489068 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 9,111E-03 0,06470205 ! B cell homeostasis GO:0001782 13 5 0,000 9,111E-03 0,06451451 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 9,111E-03 0,06432805 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,111E-03 0,06414266 ! metaphase GO:0051323 11 5 0,000 9,111E-03 0,06395835 ! melatonin biosynthetic process GO:0030187 7 5 0,000 9,111E-03 0,06377508 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 9,111E-03 0,06359287 ! cellular response to nutrient GO:0031670 8 5 0,000 9,111E-03 0,06341169 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,111E-03 0,06323155 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 9,111E-03 0,06305242 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 9,111E-03 0,06287431 ! regulation of hair follicle development GO:0051797 10 5 0,000 9,111E-03 0,0626972 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 9,111E-03 0,06252108 ! response to redox state GO:0051775 6 5 0,000 9,111E-03 0,06234595 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 9,111E-03 0,0621718 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 9,111E-03 0,06199862 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,111E-03 0,0618264 ! brown fat cell differentiation GO:0050873 7 5 0,000 9,111E-03 0,06165514 ! regulation of telomerase activity GO:0051972 7 5 0,000 9,111E-03 0,06148482 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,111E-03 0,06131544 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 9,111E-03 0,06114699 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,111E-03 0,06097946 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 9,111E-03 0,06081285 ! striatum development GO:0021756 14 5 0,000 9,111E-03 0,06064715 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 9,111E-03 0,06048235 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,111E-03 0,06031844 ! glial cell migration GO:0008347 10 5 0,000 9,111E-03 0,06015542 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,111E-03 0,05999327 ! neural plate morphogenesis GO:0001839 7 5 0,000 9,111E-03 0,059832 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 9,111E-03 0,05967159 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,111E-03 0,05951204 ! T cell activation during immune response GO:0002286 9 5 0,000 9,111E-03 0,05935335 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,111E-03 0,05919549 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,111E-03 0,05903847 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 9,111E-03 0,05888229 ! neuroprotection GO:0043526 8 5 0,000 9,111E-03 0,05872693 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 9,111E-03 0,05857238 ! regulation of sensory perception GO:0051931 8 5 0,000 9,111E-03 0,05841865 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,111E-03 0,05826572 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,111E-03 0,05811359 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 9,111E-03 0,05796225 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 9,111E-03 0,0578117 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,111E-03 0,05766193 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 9,111E-03 0,05751293 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,111E-03 0,0573647 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 9,111E-03 0,05721724 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 9,111E-03 0,05707052 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 9,111E-03 0,05692456 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,111E-03 0,05677935 ! spindle assembly GO:0051225 6 5 0,000 9,111E-03 0,05663487 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,111E-03 0,05649113 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,111E-03 0,05634811 ! protein palmitoylation GO:0018345 12 5 0,000 9,111E-03 0,05620582 ! drug metabolic process GO:0017144 7 5 0,000 9,111E-03 0,05606424 ! stem cell division GO:0017145 11 5 0,000 9,111E-03 0,05592338 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,111E-03 0,05578322 ! organ regeneration GO:0031100 7 5 0,000 9,111E-03 0,05564376 ! carnitine metabolic process GO:0009437 8 5 0,000 9,111E-03 0,055505 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,111E-03 0,05536693 ! blood coagulation GO:0007596 151 79 1,000 9,267E-03 0,05617399 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 1,000 9,267E-03 0,05603495 ! hemostasis GO:0007599 165 85 1,000 0,01066213 0,06431501 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01092304 0,06572657 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01092304 0,06556508 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01092304 0,06540438 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01092304 0,06524446 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01092304 0,06508533 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01092304 0,06492697 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01092304 0,06476938 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01092304 0,06461256 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01092304 0,06445649 ! response to oxygen radical GO:0000305 11 6 0,000 0,01092304 0,06430117 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01092304 0,0641466 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01092304 0,06399277 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01092304 0,06383968 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01092304 0,06368732 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01092304 0,06353568 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01092304 0,06338476 ! forebrain regionalization GO:0021871 9 6 0,000 0,01092304 0,06323456 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01092304 0,06308507 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01092304 0,06293629 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01092304 0,0627882 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01092304 0,06264081 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01092304 0,06249411 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01092304 0,0623481 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01092304 0,06220276 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01092304 0,06205811 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01092304 0,06191412 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01092304 0,0617708 ! malate metabolic process GO:0006108 13 6 0,000 0,01092304 0,06162814 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01092304 0,06148614 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01092304 0,0613448 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01092304 0,0612041 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01092304 0,06106404 ! protein refolding GO:0042026 15 6 0,000 0,01092304 0,06092463 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01092304 0,06078585 ! opsonization GO:0008228 8 6 0,000 0,01092304 0,0606477 ! mating behavior GO:0007617 7 6 0,000 0,01092304 0,06051017 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01092304 0,06037327 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01092304 0,06023699 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01092304 0,06010132 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01092304 0,05996626 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01092304 0,05983181 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01092304 0,05969796 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01092304 0,0595647 ! toxin metabolic process GO:0009404 11 6 0,000 0,01092304 0,05943204 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01092304 0,05929997 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01092304 0,05916848 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01092304 0,05903758 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01092304 0,05890725 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01092304 0,0587775 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01092304 0,05864832 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01092304 0,05851971 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01092304 0,05839165 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01092304 0,05826416 ! thymic T cell selection GO:0045061 16 6 0,000 0,01092304 0,05813722 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01092304 0,05801084 ! protein lipoylation GO:0009249 10 6 0,000 0,01092304 0,057885 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01092304 0,05775971 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01092304 0,05763496 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01092304 0,05751075 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01092304 0,05738707 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01092304 0,05726392 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01092304 0,0571413 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01092304 0,0570192 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01092304 0,05689762 ! hyperosmotic response GO:0006972 10 6 0,000 0,01092304 0,05677657 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01092304 0,05665602 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01092304 0,05653599 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01092304 0,05641646 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01092304 0,05629744 ! urea metabolic process GO:0019627 7 6 0,000 0,01092304 0,05617892 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01092304 0,0560609 ! neutrophil activation GO:0042119 7 6 0,000 0,01092304 0,05594337 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01092304 0,05582633 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01092304 0,05570978 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01092304 0,05559372 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01092304 0,05547814 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01092304 0,05536304 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01092304 0,05524842 ! neuron apoptosis GO:0051402 15 6 0,000 0,01092304 0,05513427 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01092304 0,05502059 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01092304 0,05490738 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01092304 0,05479463 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01092304 0,05468235 ! carnitine transport GO:0015879 10 6 0,000 0,01092304 0,05457052 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01092304 0,05445916 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01092304 0,05434824 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01092304 0,05423778 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01092304 0,05412776 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01092304 0,05401819 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01092304 0,05390906 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01092304 0,05380038 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01092304 0,05369212 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01092304 0,05358431 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01092304 0,05347693 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01092304 0,05336997 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01092304 0,05326345 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01092304 0,05315734 ! response to UV-C GO:0010225 14 6 0,000 0,01092304 0,05305166 ! astrocyte development GO:0014002 16 6 0,000 0,01092304 0,0529464 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01092304 0,05284156 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01092304 0,05273713 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01092304 0,05263311 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01092304 0,0525295 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01092304 0,0524263 ! response to copper ion GO:0046688 10 6 0,000 0,01092304 0,0523235 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01092304 0,05222111 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01092304 0,05211911 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01092304 0,05201752 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01092304 0,05191632 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01092304 0,05181551 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01092304 0,05171509 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01092304 0,05161506 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01092304 0,05151542 ! hair follicle maturation GO:0048820 8 6 0,000 0,01092304 0,05141616 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01092304 0,05131728 ! Schwann cell development GO:0014044 15 6 0,000 0,01092304 0,05121878 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01092304 0,05112066 ! response to pheromone GO:0019236 6 6 0,000 0,01092304 0,05102292 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01092304 0,05092555 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01092304 0,05082854 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01092304 0,05073191 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01092304 0,05063565 ! subpallium development GO:0021544 15 6 0,000 0,01092304 0,05053975 ! neural tube patterning GO:0021532 8 6 0,000 0,01092304 0,05044421 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01092304 0,05034903 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01092304 0,05025421 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01092304 0,05015975 ! G2 phase GO:0051319 16 6 0,000 0,01092304 0,05006564 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01092304 0,04997188 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01092304 0,04987848 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01092304 0,04978542 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01092304 0,04969271 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01092304 0,04960035 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01092304 0,04950832 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01092304 0,04941664 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01092304 0,0493253 ! receptor internalization GO:0031623 11 6 0,000 0,01092304 0,04923429 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01092304 0,04914362 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01092304 0,04905328 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01092304 0,04896328 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01092304 0,0488736 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01092304 0,04878425 ! protein deubiquitination GO:0016579 16 6 0,000 0,01092304 0,04869523 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01092304 0,04860653 ! protein destabilization GO:0031648 9 6 0,000 0,01092304 0,04851816 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01092304 0,0484301 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01092304 0,04834237 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01092304 0,04825495 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01092304 0,04816784 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01092304 0,04808106 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01092304 0,04799458 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01092304 0,04790841 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01092304 0,04782256 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01092304 0,04773701 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01092304 0,04765176 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01092304 0,04756682 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01092304 0,04748218 ! neural plate development GO:0001840 9 6 0,000 0,01092304 0,04739784 ! catecholamine transport GO:0051937 9 6 0,000 0,01092304 0,04731381 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01092304 0,04723006 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01092304 0,04714662 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01092304 0,04706347 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01092304 0,04698061 ! maternal placenta development GO:0001893 12 6 0,000 0,01092304 0,04689804 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01092304 0,04681576 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01092304 0,04673378 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01092304 0,04665207 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01092304 0,04657066 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01092304 0,04648952 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01092304 0,04640867 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01092304 0,0463281 GO:0055081|anion homeostasis, ! nucleosome assembly GO:0006334 126 87 1,000 0,01114673 0,0471949 ! chromatin assembly GO:0031497 128 88 1,000 0,01139262 0,04815256 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,01189156 0,05017457 ! gland development GO:0048732 220 91 1,000 0,01214458 0,05115381 ! ossification GO:0001503 205 91 1,000 0,01214458 0,05106576 ! bone development GO:0060348 206 92 1,000 0,01239996 0,05204999 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,01239996 0,05196071 ! tRNA transcription GO:0009304 17 7 0,000 0,01273209 0,05326112 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01273209 0,05317008 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01273209 0,05307934 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01273209 0,05298892 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01273209 0,0528988 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01273209 0,05280899 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01273209 0,05271948 ! sleep GO:0030431 16 7 0,000 0,01273209 0,05263028 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01273209 0,05254138 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01273209 0,05245277 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01273209 0,05236447 ! prostate gland development GO:0030850 14 7 0,000 0,01273209 0,05227646 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01273209 0,05218875 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01273209 0,05210133 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01273209 0,0520142 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01273209 0,05192737 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01273209 0,05184082 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01273209 0,05175457 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01273209 0,05166859 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01273209 0,05158291 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01273209 0,05149751 ! glycolipid transport GO:0046836 11 7 0,000 0,01273209 0,05141239 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01273209 0,05132755 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01273209 0,05124299 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01273209 0,05115871 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01273209 0,0510747 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01273209 0,05099097 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01273209 0,05090752 ! mRNA stabilization GO:0048255 18 7 0,000 0,01273209 0,05082434 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01273209 0,05074143 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01273209 0,05065879 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01273209 0,05057641 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01273209 0,05049431 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01273209 0,05041247 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01273209 0,0503309 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01273209 0,05024959 ! lipoprotein transport GO:0042953 14 7 0,000 0,01273209 0,05016854 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01273209 0,05008775 ! rhythmic behavior GO:0007622 17 7 0,000 0,01273209 0,05000723 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01273209 0,04992696 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01273209 0,04984695 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01273209 0,04976719 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01273209 0,04968769 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01273209 0,04960844 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01273209 0,04952945 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01273209 0,04945071 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01273209 0,04937221 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01273209 0,04929397 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01273209 0,04921597 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01273209 0,04913822 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01273209 0,04906072 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01273209 0,04898346 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01273209 0,04890644 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01273209 0,04882966 ! spinal cord patterning GO:0021511 14 7 0,000 0,01273209 0,04875313 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01273209 0,04867683 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01273209 0,04860077 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01273209 0,04852495 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01273209 0,04844937 ! adrenal gland development GO:0030325 17 7 0,000 0,01273209 0,04837402 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01273209 0,0482989 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01273209 0,04822402 ! ovulation GO:0030728 10 7 0,000 0,01273209 0,04814937 ! adenohypophysis development GO:0021984 11 7 0,000 0,01273209 0,04807495 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01273209 0,04800076 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01273209 0,0479268 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01273209 0,04785307 ! microtubule nucleation GO:0007020 21 7 0,000 0,01273209 0,04777956 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01273209 0,04770628 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01273209 0,04763322 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01273209 0,04756039 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01273209 0,04748778 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01273209 0,04741539 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01273209 0,04734322 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01273209 0,04727127 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01273209 0,04719954 ! galactose metabolic process GO:0006012 13 7 0,000 0,01273209 0,04712802 ! vesicle fusion GO:0006906 20 7 0,000 0,01273209 0,04705672 ! response to dietary excess GO:0002021 8 7 0,000 0,01273209 0,04698564 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01273209 0,04691477 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01273209 0,04684412 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01273209 0,04677368 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01273209 0,04670344 ! organ growth GO:0035265 15 7 0,000 0,01273209 0,04663342 ! nucleoside transport GO:0015858 11 7 0,000 0,01273209 0,04656361 ! nucleoside salvage GO:0043174 11 7 0,000 0,01273209 0,04649401 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01273209 0,04642462 ! male sex determination GO:0030238 15 7 0,000 0,01273209 0,04635543 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01273209 0,04628645 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01273209 0,04621767 ! parturition GO:0007567 16 7 0,000 0,01273209 0,0461491 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01273209 0,04608073 ! rRNA modification GO:0000154 14 7 0,000 0,01273209 0,04601257 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01273209 0,0459446 ! spindle checkpoint GO:0031577 16 7 0,000 0,01273209 0,04587683 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01273209 0,04580927 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01273209 0,0457419 ! monocyte differentiation GO:0030224 16 7 0,000 0,01273209 0,04567473 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01273209 0,04560776 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01273209 0,04554099 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01273209 0,04547441 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01273209 0,04540802 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01273209 0,04534183 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01273209 0,04527583 ! fibrinolysis GO:0042730 11 7 0,000 0,01273209 0,04521002 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01273209 0,0451444 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01273209 0,04507898 ! eating behavior GO:0042755 8 7 0,000 0,01273209 0,04501374 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01273209 0,04494869 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01273209 0,04488383 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01273209 0,04481916 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01273209 0,04475467 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01273209 0,04469037 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01273209 0,04462625 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01273209 0,04456231 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01273209 0,04449856 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01273209 0,04443499 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01273209 0,0443716 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01273209 0,0443084 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01273209 0,04424537 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01273209 0,04418252 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01273209 0,04411985 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01273209 0,04405736 ! histone ubiquitination GO:0016574 9 7 0,000 0,01273209 0,04399504 ! regulation of meiosis GO:0040020 12 7 0,000 0,01273209 0,0439329 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 0,000 0,01273209 0,04387094 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01273209 0,04380915 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01273209 0,04374753 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01273209 0,04368609 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01273209 0,04362482 ! anaphase GO:0051322 18 7 0,000 0,01273209 0,04356372 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01273209 0,04350279 ! axonal fasciculation GO:0007413 19 7 0,000 0,01273209 0,04344203 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01273209 0,04338144 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01273209 0,04332102 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01273209 0,04326077 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01273209 0,04320069 ! diuresis GO:0030146 12 7 0,000 0,01273209 0,04314077 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01273209 0,04308102 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01273209 0,04302143 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01273209 0,04296201 ! antibiotic transport GO:0042891 9 7 0,000 0,01273209 0,04290275 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01273209 0,04284366 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01273209 0,04278472 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01273209 0,04272595 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01273209 0,04266734 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01273209 0,0426089 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01273209 0,04255061 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01273209 0,04249248 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01273209 0,04243451 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01273209 0,04237669 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01273209 0,04231904 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01273209 0,04226154 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01273209 0,0422042 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01273209 0,04214701 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01273209 0,04208998 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01273209 0,0420331 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01273209 0,04197638 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01273209 0,0419198 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01273209 0,04186338 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01273209 0,04180712 ! muscle adaptation GO:0043500 13 7 0,000 0,01273209 0,041751 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01273209 0,04169503 ! retina homeostasis GO:0001895 12 7 0,000 0,01273209 0,04163922 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01273209 0,04158355 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01273209 0,04152803 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01273209 0,04147266 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01273209 0,04141744 ! nucleosome organization GO:0034728 143 95 1,000 0,01318014 0,04281793 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,01371188 0,04448621 ! transcription initiation GO:0006352 171 97 1,000 0,01371188 0,04442721 ! mRNA transport GO:0051028 185 100 1,000 0,01452672 0,04700502 ! positive regulation of immune response GO:0050778 175 100 1,000 0,01452672 0,04694284 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01453788 0,04691683 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01453788 0,04685494 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01453788 0,04679321 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01453788 0,04673164 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01453788 0,04667023 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01453788 0,04660898 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01453788 0,04654789 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01453788 0,04648697 ! male meiosis GO:0007140 9 8 0,000 0,01453788 0,0464262 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01453788 0,04636559 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01453788 0,04630514 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01453788 0,04624485 ! meiotic prophase I GO:0007128 14 8 0,000 0,01453788 0,04618471 ! response to zinc ion GO:0010043 12 8 0,000 0,01453788 0,04612473 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01453788 0,04606491 ! oligopeptide transport GO:0006857 16 8 0,000 0,01453788 0,04600524 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01453788 0,04594572 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01453788 0,04588636 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01453788 0,04582715 ! signal peptide processing GO:0006465 12 8 0,000 0,01453788 0,0457681 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01453788 0,04570919 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01453788 0,04565044 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01453788 0,04559184 ! succinate metabolic process GO:0006105 17 8 0,000 0,01453788 0,04553339 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01453788 0,04547509 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01453788 0,04541693 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01453788 0,04535893 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01453788 0,04530108 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01453788 0,04524337 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01453788 0,04518581 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01453788 0,04512839 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01453788 0,04507112 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01453788 0,045014 ! reflex GO:0060004 17 8 0,000 0,01453788 0,04495702 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01453788 0,04490018 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01453788 0,04484349 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01453788 0,04478694 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01453788 0,04473053 ! pigment granule organization GO:0048753 17 8 0,000 0,01453788 0,04467427 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01453788 0,04461814 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01453788 0,04456216 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01453788 0,04450632 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01453788 0,04445062 ! histidine catabolic process GO:0006548 10 8 0,000 0,01453788 0,04439505 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01453788 0,04433963 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01453788 0,04428434 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01453788 0,04422919 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01453788 0,04417418 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01453788 0,04411931 ! melanin metabolic process GO:0006582 17 8 0,000 0,01453788 0,04406457 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01453788 0,04400997 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01453788 0,0439555 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01453788 0,04390117 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01453788 0,04384697 ! macrophage activation GO:0042116 13 8 0,000 0,01453788 0,0437929 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01453788 0,04373897 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01453788 0,04368517 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01453788 0,0436315 ! purine salvage GO:0043101 12 8 0,000 0,01453788 0,04357797 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01453788 0,04352456 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01453788 0,04347129 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01453788 0,04341815 ! osteoblast development GO:0002076 17 8 0,000 0,01453788 0,04336513 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01453788 0,04331225 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01453788 0,04325949 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01453788 0,04320686 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01453788 0,04315437 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01453788 0,04310199 ! response to UV-B GO:0010224 17 8 0,000 0,01453788 0,04304975 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01453788 0,04299763 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01453788 0,04294564 ! intermediate filament organization GO:0045109 12 8 0,000 0,01453788 0,04289377 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01453788 0,04284203 ! cellular extravasation GO:0045123 13 8 0,000 0,01453788 0,04279041 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01453788 0,04273892 ! response to antibiotic GO:0046677 11 8 0,000 0,01453788 0,04268755 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01453788 0,04263631 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01453788 0,04258518 ! DNA topological change GO:0006265 12 8 0,000 0,01453788 0,04253418 ! response to tropane GO:0014073 15 8 0,000 0,01453788 0,0424833 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01453788 0,04243255 ! melanosome transport GO:0032402 13 8 0,000 0,01453788 0,04238191 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01453788 0,0423314 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01453788 0,042281 ! mast cell activation GO:0045576 14 8 0,000 0,01453788 0,04223073 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01453788 0,04218057 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01453788 0,04213054 ! gas homeostasis GO:0033483 14 8 0,000 0,01453788 0,04208062 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01453788 0,04203082 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01453788 0,04198114 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01453788 0,04193157 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01453788 0,04188213 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01453788 0,04183279 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01453788 0,04178358 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01453788 0,04173448 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01453788 0,0416855 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01453788 0,04163663 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01453788 0,04158787 ! response to tumor cell GO:0002347 16 8 0,000 0,01453788 0,04153923 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01453788 0,0414907 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01453788 0,04144229 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01453788 0,04139399 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01453788 0,0413458 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01453788 0,04129772 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01453788 0,04124976 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01453788 0,04120191 ! hormone catabolic process GO:0042447 17 8 0,000 0,01453788 0,04115416 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01453788 0,04110653 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01453788 0,04105901 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01453788 0,0410116 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01453788 0,04096429 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01453788 0,0409171 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01453788 0,04087001 ! adult feeding behavior GO:0008343 10 8 0,000 0,01453788 0,04082304 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01453788 0,04077617 ! ATP catabolic process GO:0006200 11 8 0,000 0,01453788 0,04072941 ! blastocyst growth GO:0001832 19 8 0,000 0,01453788 0,04068275 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01453788 0,0406362 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01453788 0,04058976 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01453788 0,04054343 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01453788 0,0404972 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01453788 0,04045107 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01453788 0,04040505 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01453788 0,04035914 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01453788 0,04031333 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01453788 0,04026762 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01453788 0,04022202 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01453788 0,04017652 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01453788 0,04013112 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01453788 0,04008583 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01453788 0,04004063 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01453788 0,03999554 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01453788 0,03995055 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01453788 0,03990567 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01453788 0,03986088 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01453788 0,03981619 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01453788 0,0397716 ! axon extension GO:0048675 16 9 0,000 0,01634042 0,04465285 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01634042 0,04460296 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01634042 0,04455318 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01634042 0,04450351 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01634042 0,04445395 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01634042 0,0444045 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01634042 0,04435516 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01634042 0,04430593 ! reproductive behavior GO:0019098 22 9 0,000 0,01634042 0,04425681 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01634042 0,0442078 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01634042 0,0441589 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01634042 0,04411011 ! UTP metabolic process GO:0046051 10 9 0,000 0,01634042 0,04406142 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01634042 0,04401284 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01634042 0,04396437 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01634042 0,043916 ! artery development GO:0060840 25 9 0,000 0,01634042 0,04386774 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01634042 0,04381959 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01634042 0,04377154 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01634042 0,0437236 ! equilibrioception GO:0050957 20 9 0,000 0,01634042 0,04367576 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01634042 0,04362803 ! chemosensory behavior GO:0007635 21 9 0,000 0,01634042 0,0435804 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01634042 0,04353288 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01634042 0,04348545 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01634042 0,04343814 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01634042 0,04339092 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01634042 0,04334381 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01634042 0,0432968 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01634042 0,04324989 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01634042 0,04320308 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01634042 0,04315637 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01634042 0,04310977 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01634042 0,04306326 ! protein targeting to ER GO:0045047 25 9 0,000 0,01634042 0,04301686 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01634042 0,04297056 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01634042 0,04292435 ! T cell selection GO:0045058 27 9 0,000 0,01634042 0,04287825 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01634042 0,04283224 ! glycine catabolic process GO:0006546 15 9 0,000 0,01634042 0,04278633 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01634042 0,04274052 ! endosome organization GO:0007032 20 9 0,000 0,01634042 0,04269481 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01634042 0,04264919 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01634042 0,04260368 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01634042 0,04255826 ! mannose metabolic process GO:0006013 13 9 0,000 0,01634042 0,04251294 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01634042 0,04246771 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01634042 0,04242258 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01634042 0,04237754 ! receptor clustering GO:0043113 20 9 0,000 0,01634042 0,0423326 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01634042 0,04228776 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01634042 0,04224301 ! retinol metabolic process GO:0042572 20 9 0,000 0,01634042 0,04219836 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01634042 0,0421538 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01634042 0,04210933 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01634042 0,04206496 ! macrophage differentiation GO:0030225 15 9 0,000 0,01634042 0,04202068 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01634042 0,04197649 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01634042 0,0419324 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01634042 0,0418884 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01634042 0,04184449 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01634042 0,04180068 ! response to amine stimulus GO:0014075 13 9 0,000 0,01634042 0,04175695 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01634042 0,04171332 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01634042 0,04166978 ! erythrocyte development GO:0048821 17 9 0,000 0,01634042 0,04162633 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01634042 0,04158296 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01634042 0,04153969 ! renal water homeostasis GO:0003091 15 9 0,000 0,01634042 0,04149651 ! postreplication repair GO:0006301 25 9 0,000 0,01634042 0,04145342 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01634042 0,04141042 ! icosanoid secretion GO:0032309 15 9 0,000 0,01634042 0,04136751 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01634042 0,04132469 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01634042 0,04128195 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01634042 0,0412393 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01634042 0,04119675 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01634042 0,04115427 ! sterol catabolic process GO:0016127 14 9 0,000 0,01634042 0,04111189 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01634042 0,0410696 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01634042 0,04102739 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01634042 0,04098526 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01634042 0,04094323 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01634042 0,04090128 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01634042 0,04085941 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01634042 0,04081763 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01634042 0,04077594 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01634042 0,04073433 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01634042 0,04069281 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01634042 0,04065137 ! purine base metabolic process GO:0006144 25 9 0,000 0,01634042 0,04061002 ! pigment granule transport GO:0051904 17 9 0,000 0,01634042 0,04056875 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01634042 0,04052756 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01634042 0,04048646 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01634042 0,04044544 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01634042 0,0404045 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01634042 0,04036365 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01634042 0,04032288 ! mitochondrion localization GO:0051646 18 9 0,000 0,01634042 0,04028219 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01813971 0,0446727 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01813971 0,04462771 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01813971 0,04458282 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01813971 0,04453801 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01813971 0,04449329 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01813971 0,04444866 ! associative learning GO:0008306 21 10 0,000 0,01813971 0,04440413 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01813971 0,04435968 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01813971 0,04431532 ! phosphate transport GO:0006817 24 10 0,000 0,01813971 0,04427105 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01813971 0,04422687 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01813971 0,04418277 ! CTP metabolic process GO:0046036 11 10 0,000 0,01813971 0,04413876 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01813971 0,04409484 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01813971 0,04405101 ! GTP metabolic process GO:0046039 11 10 0,000 0,01813971 0,04400727 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01813971 0,04396361 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01813971 0,04392004 ! social behavior GO:0035176 29 10 0,000 0,01813971 0,04387655 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01813971 0,04383315 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01813971 0,04378984 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01813971 0,04374661 ! androgen metabolic process GO:0008209 17 10 0,000 0,01813971 0,04370347 ! phospholipid efflux GO:0033700 19 10 0,000 0,01813971 0,04366041 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01813971 0,04361744 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01813971 0,04357455 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01813971 0,04353175 ! lung alveolus development GO:0048286 26 10 0,000 0,01813971 0,04348903 ! pathogenesis GO:0009405 17 10 0,000 0,01813971 0,04344639 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01813971 0,04340384 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01813971 0,04336137 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01813971 0,04331898 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01813971 0,04327668 ! endoderm development GO:0007492 18 10 0,000 0,01813971 0,04323446 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01813971 0,04319232 ! arginine catabolic process GO:0006527 17 10 0,000 0,01813971 0,04315026 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01813971 0,04310829 ! proline metabolic process GO:0006560 13 10 0,000 0,01813971 0,04306639 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01813971 0,04302458 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01813971 0,04298285 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01813971 0,0429412 ! V(D)J recombination GO:0033151 34 10 0,000 0,01813971 0,04289963 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01813971 0,04285814 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01813971 0,04281673 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01813971 0,0427754 ! B cell proliferation GO:0042100 19 10 0,000 0,01813971 0,04273416 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01813971 0,04269299 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01813971 0,0426519 ! multicellular organism growth GO:0035264 19 10 0,000 0,01813971 0,04261088 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01813971 0,04256995 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01813971 0,0425291 ! ruffle organization GO:0031529 17 10 0,000 0,01813971 0,04248832 ! epithelial cell development GO:0002064 21 10 0,000 0,01813971 0,04244762 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01813971 0,042407 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01813971 0,04236646 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01813971 0,042326 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01813971 0,04228561 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01813971 0,0422453 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01813971 0,04220507 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01813971 0,04216491 ! motor axon guidance GO:0008045 22 10 0,000 0,01813971 0,04212483 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01813971 0,04208482 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01813971 0,04204489 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01813971 0,04200504 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01813971 0,04196526 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01813971 0,04192556 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01813971 0,04188593 ! segment specification GO:0007379 15 10 0,000 0,01813971 0,04184638 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01813971 0,0418069 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01813971 0,0417675 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01813971 0,04172817 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01813971 0,04168892 ! response to dsRNA GO:0043331 23 10 0,000 0,01813971 0,04164974 ! DNA ligation GO:0006266 18 10 0,000 0,01813971 0,04161063 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01813971 0,04157159 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01813971 0,04153263 ! melanosome localization GO:0032400 16 10 0,000 0,01813971 0,04149374 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01813971 0,04145493 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01813971 0,04141619 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01813971 0,04137752 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01813971 0,04133892 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01813971 0,04130039 ! induction of an organ GO:0001759 17 10 0,000 0,01813971 0,04126194 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01813971 0,04122355 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01813971 0,04118524 ! protein sumoylation GO:0016925 17 10 0,000 0,01813971 0,041147 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01813971 0,04110883 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01813971 0,04107073 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01813971 0,0410327 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01813971 0,04099474 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01813971 0,04095686 ! salivary gland development GO:0007431 28 10 0,000 0,01813971 0,04091904 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01813971 0,04088129 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01813971 0,04084361 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01813971 0,040806 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01813971 0,04076846 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01813971 0,04073099 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01813971 0,04069359 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01813971 0,04065626 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01813971 0,04061899 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01813971 0,04058179 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01813971 0,04054467 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01813971 0,0405076 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01813971 0,04047061 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01813971 0,04043369 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01813971 0,04039683 ! blastocyst formation GO:0001825 18 10 0,000 0,01813971 0,04036004 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01813971 0,04032331 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01813971 0,04028665 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01813971 0,04025006 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01813971 0,04021354 ! response to nicotine GO:0035094 20 10 0,000 0,01813971 0,04017708 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01813971 0,04014069 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01813971 0,04010436 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01993577 0,04403533 ! respiratory burst GO:0045730 17 11 0,000 0,01993577 0,04399555 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01993577 0,04395584 ! neuron fate specification GO:0048665 18 11 0,000 0,01993577 0,04391621 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01993577 0,04387664 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01993577 0,04383715 ! thyroid gland development GO:0030878 26 11 0,000 0,01993577 0,04379773 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01993577 0,04375838 ! synapsis GO:0007129 14 11 0,000 0,01993577 0,0437191 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01993577 0,04367989 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01993577 0,04364075 ! response to pain GO:0048265 27 11 0,000 0,01993577 0,04360168 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01993577 0,04356268 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01993577 0,04352375 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01993577 0,04348489 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01993577 0,0434461 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01993577 0,04340737 ! bone resorption GO:0045453 16 11 0,000 0,01993577 0,04336872 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01993577 0,04333014 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01993577 0,04329162 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01993577 0,04325317 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01993577 0,0432148 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01993577 0,04317648 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01993577 0,04313824 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01993577 0,04310007 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01993577 0,04306196 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01993577 0,04302392 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01993577 0,04298594 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01993577 0,04294804 ! UV protection GO:0009650 20 11 0,000 0,01993577 0,0429102 ! adult heart development GO:0007512 16 11 0,000 0,01993577 0,04287242 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01993577 0,04283472 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01993577 0,04279708 ! macroautophagy GO:0016236 19 11 0,000 0,01993577 0,0427595 ! temperature homeostasis GO:0001659 18 11 0,000 0,01993577 0,042722 ! behavioral fear response GO:0001662 27 11 0,000 0,01993577 0,04268455 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01993577 0,04264718 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01993577 0,04260986 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01993577 0,04257262 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01993577 0,04253544 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01993577 0,04249832 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01993577 0,04246127 ! regulation of organ growth GO:0046620 14 11 0,000 0,01993577 0,04242428 ! pigment granule localization GO:0051875 20 11 0,000 0,01993577 0,04238736 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01993577 0,0423505 ! vasoconstriction GO:0042310 20 11 0,000 0,01993577 0,0423137 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01993577 0,04227697 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01993577 0,04224031 ! embryonic axis specification GO:0000578 19 11 0,000 0,01993577 0,0422037 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01993577 0,04216716 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01993577 0,04213069 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01993577 0,04209427 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01993577 0,04205792 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01993577 0,04202163 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01993577 0,04198541 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01993577 0,04194925 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01993577 0,04191314 ! prophase GO:0051324 17 11 0,000 0,01993577 0,04187711 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01993577 0,04184113 ! nucleosome positioning GO:0016584 15 11 0,000 0,01993577 0,04180521 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01993577 0,04176936 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01993577 0,04173357 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01993577 0,04169784 ! apical protein localization GO:0045176 18 11 0,000 0,01993577 0,04166217 ! acid secretion GO:0046717 20 11 0,000 0,01993577 0,04162656 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01993577 0,04159101 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01993577 0,04155552 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01993577 0,0415201 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01993577 0,04148473 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01993577 0,04144943 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01993577 0,04141418 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01993577 0,04137899 ! cholesterol efflux GO:0033344 21 11 0,000 0,01993577 0,04134387 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01993577 0,0413088 ! oocyte development GO:0048599 20 11 0,000 0,01993577 0,04127379 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01993577 0,04123884 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01993577 0,04120395 ! embryonic gut development GO:0048566 19 11 0,000 0,01993577 0,04116912 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01993577 0,04113435 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01993577 0,04109964 ! activation of innate immune response GO:0002218 16 11 0,000 0,01993577 0,04106499 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01993577 0,04103039 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01993577 0,04099585 ! lysogeny GO:0030069 22 11 0,000 0,01993577 0,04096137 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01993577 0,04092695 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01993577 0,04089259 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01993577 0,04085828 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01993577 0,04082404 ! nucleus localization GO:0051647 22 11 0,000 0,01993577 0,04078984 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02172858 0,04442086 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02172858 0,04438372 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02172858 0,04434664 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02172858 0,04430962 ! virus-host interaction GO:0019048 30 12 0,000 0,02172858 0,04427267 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02172858 0,04423577 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02172858 0,04419894 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02172858 0,04416217 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02172858 0,04412546 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02172858 0,04408881 ! hippocampus development GO:0021766 29 12 0,000 0,02172858 0,04405222 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02172858 0,04401569 ! T cell proliferation GO:0042098 32 12 0,000 0,02172858 0,04397923 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02172858 0,04394282 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02172858 0,04390647 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02172858 0,04387019 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02172858 0,04383396 ! drug transport GO:0015893 16 12 0,000 0,02172858 0,04379779 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02172858 0,04376169 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02172858 0,04372564 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02172858 0,04368965 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02172858 0,04365372 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02172858 0,04361785 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02172858 0,04358204 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02172858 0,04354629 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02172858 0,0435106 ! lipid digestion GO:0044241 21 12 0,000 0,02172858 0,04347496 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02172858 0,04343938 ! entry into host cell GO:0030260 34 12 0,000 0,02172858 0,04340387 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02172858 0,0433684 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02172858 0,043333 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02172858 0,04329766 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02172858 0,04326237 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02172858 0,04322714 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02172858 0,04319197 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02172858 0,04315685 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02172858 0,04312179 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02172858 0,04308679 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02172858 0,04305185 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02172858 0,04301696 ! cranial nerve development GO:0021545 23 12 0,000 0,02172858 0,04298213 ! fucose catabolic process GO:0019317 25 12 0,000 0,02172858 0,04294735 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02172858 0,04291263 ! histone acetylation GO:0016573 27 12 0,000 0,02172858 0,04287797 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02172858 0,04284336 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02172858 0,04280881 ! zymogen activation GO:0031638 18 12 0,000 0,02172858 0,04277432 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02172858 0,04273988 ! T cell homeostasis GO:0043029 28 12 0,000 0,02172858 0,04270549 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02172858 0,04267116 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02172858 0,04263689 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02172858 0,04260267 ! oocyte differentiation GO:0009994 21 12 0,000 0,02172858 0,04256851 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02172858 0,0425344 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02172858 0,04250034 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02172858 0,04246634 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02172858 0,0424324 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02172858 0,0423985 ! defense response to fungus GO:0050832 15 12 0,000 0,02172858 0,04236467 ! developmental induction GO:0031128 22 12 0,000 0,02172858 0,04233088 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02172858 0,04229715 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02172858 0,04226348 ! response to cold GO:0009409 17 12 0,000 0,02172858 0,04222985 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02172858 0,04219629 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02172858 0,04216277 ! localization within membrane GO:0051668 26 12 0,000 0,02172858 0,04212931 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02351817 0,04556296 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02351817 0,04552685 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02351817 0,04549081 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02351817 0,04545482 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02351817 0,04541889 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02351817 0,04538301 ! peroxisomal transport GO:0043574 28 13 0,000 0,02351817 0,04534719 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02351817 0,04531143 ! cartilage condensation GO:0001502 22 13 0,000 0,02351817 0,04527572 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02351817 0,04524007 ! organelle fusion GO:0048284 36 13 0,000 0,02351817 0,04520448 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02351817 0,04516894 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02351817 0,04513346 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02351817 0,04509803 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02351817 0,04506266 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02351817 0,04502734 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02351817 0,04499208 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02351817 0,04495688 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02351817 0,04492173 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02351817 0,04488663 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02351817 0,04485159 ! methionine metabolic process GO:0006555 31 13 0,000 0,02351817 0,04481661 ! plasma membrane organization GO:0007009 27 13 0,000 0,02351817 0,04478168 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02351817 0,0447468 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02351817 0,04471198 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02351817 0,04467721 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02351817 0,04464249 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02351817 0,04460783 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02351817 0,04457323 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02351817 0,04453867 ! exocrine system development GO:0035272 34 13 0,000 0,02351817 0,04450418 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02351817 0,04446973 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02351817 0,04443534 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02351817 0,044401 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02351817 0,04436671 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02351817 0,04433248 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02351817 0,0442983 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02351817 0,04426417 ! protein homotetramerization GO:0051289 24 13 0,000 0,02351817 0,04423009 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02351817 0,04419607 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02351817 0,0441621 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02351817 0,04412818 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02351817 0,04409431 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02351817 0,0440605 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02351817 0,04402674 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,02351817 0,04399302 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02351817 0,04395937 ! histone methylation GO:0016571 29 13 0,000 0,02351817 0,04392576 ! chromatin silencing GO:0006342 29 13 0,000 0,02351817 0,0438922 ! gland morphogenesis GO:0022612 31 13 0,000 0,02351817 0,0438587 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02351817 0,04382524 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02351817 0,04379184 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02351817 0,04375848 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02351817 0,04372518 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02351817 0,04369193 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02351817 0,04365873 ! spleen development GO:0048536 24 13 0,000 0,02351817 0,04362558 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02351817 0,04359248 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02351817 0,04355943 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02351817 0,04352643 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02351817 0,04349348 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02351817 0,04346058 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02351817 0,04342773 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02351817 0,04339493 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02351817 0,04336218 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02351817 0,04332948 ! insulin secretion GO:0030073 24 13 0,000 0,02351817 0,04329683 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02351817 0,04326422 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02351817 0,04323167 ! acrosome reaction GO:0007340 19 13 0,000 0,02351817 0,04319917 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02351817 0,04316671 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02351817 0,0431343 ! rRNA transcription GO:0009303 28 14 0,000 0,02530454 0,04637583 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02530454 0,04634106 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02530454 0,04630635 ! water transport GO:0006833 21 14 0,000 0,02530454 0,04627169 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02530454 0,04623708 ! non-recombinational repair GO:0000726 29 14 0,000 0,02530454 0,04620253 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02530454 0,04616802 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02530454 0,04613357 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02530454 0,04609916 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02530454 0,04606481 ! lipid localization GO:0010876 32 14 0,000 0,02530454 0,04603051 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,02530454 0,04599626 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02530454 0,04596207 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02530454 0,04592792 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02530454 0,04589382 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02530454 0,04585978 ! arginine metabolic process GO:0006525 21 14 0,000 0,02530454 0,04582578 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02530454 0,04579184 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02530454 0,04575794 ! regulation of heart rate GO:0002027 25 14 0,000 0,02530454 0,0457241 ! fear response GO:0042596 34 14 0,000 0,02530454 0,0456903 ! organic alcohol transport GO:0015850 29 14 0,000 0,02530454 0,04565656 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02530454 0,04562286 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02530454 0,04558922 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02530454 0,04555562 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02530454 0,04552208 ! bone mineralization GO:0030282 18 14 0,000 0,02530454 0,04548858 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02530454 0,04545513 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02530454 0,04542173 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02530454 0,04538838 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02530454 0,04535508 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02530454 0,04532183 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02530454 0,04528863 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02530454 0,04525548 ! ribosome assembly GO:0042255 18 14 0,000 0,02530454 0,04522237 ! cerebellum development GO:0021549 23 14 0,000 0,02530454 0,04518931 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02530454 0,0451563 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02530454 0,04512334 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02530454 0,04509043 ! response to gamma radiation GO:0010332 30 14 0,000 0,02530454 0,04505756 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02530454 0,04502475 ! NADP metabolic process GO:0006739 24 14 0,000 0,02530454 0,04499198 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02530454 0,04495926 ! oxygen transport GO:0015671 22 14 0,000 0,02530454 0,04492658 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02530454 0,04489396 ! male genitalia development GO:0030539 26 14 0,000 0,02530454 0,04486138 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02530454 0,04482885 ! regulation of axon extension GO:0030516 43 14 0,000 0,02530454 0,04479636 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02530454 0,04476392 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02530454 0,04473153 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,02530454 0,04469919 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02708768 0,04781446 ! lactation GO:0007595 30 15 0,000 0,02708768 0,04777993 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02708768 0,04774546 ! reproductive cellular process GO:0048610 22 15 0,000 0,02708768 0,04771104 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02708768 0,04767666 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02708768 0,04764234 ! superoxide anion generation GO:0042554 22 15 0,000 0,02708768 0,04760806 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02708768 0,04757384 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02708768 0,04753966 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02708768 0,04750553 ! copper ion transport GO:0006825 22 15 0,000 0,02708768 0,04747145 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02708768 0,04743742 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02708768 0,04740344 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02708768 0,04736951 ! sulfate transport GO:0008272 27 15 0,000 0,02708768 0,04733563 ! response to cAMP GO:0051591 25 15 0,000 0,02708768 0,04730179 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02708768 0,047268 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02708768 0,04723427 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02708768 0,04720058 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02708768 0,04716693 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02708768 0,04713334 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02708768 0,04709979 ! vesicle coating GO:0006901 38 15 0,000 0,02708768 0,04706629 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02708768 0,04703284 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02708768 0,04699944 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02708768 0,04696608 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02708768 0,04693277 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02708768 0,04689951 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02708768 0,04686629 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02708768 0,04683313 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02708768 0,0468 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02708768 0,04676693 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02708768 0,0467339 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02708768 0,04670092 ! histone deacetylation GO:0016575 24 15 0,000 0,02708768 0,04666799 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02708768 0,0466351 ! water homeostasis GO:0030104 28 15 0,000 0,02708768 0,04660226 ! cofactor transport GO:0051181 30 15 0,000 0,02708768 0,04656946 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02708768 0,04653671 ! muscle maintenance GO:0046716 26 15 0,000 0,02708768 0,04650401 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02708768 0,04647135 ! intestinal absorption GO:0050892 31 15 0,000 0,02708768 0,04643874 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02708768 0,04640618 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02708768 0,04637366 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02708768 0,04634118 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02708768 0,04630875 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02708768 0,04627637 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02708768 0,04624403 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02708768 0,04621174 ! actin filament polymerization GO:0030041 27 15 0,000 0,02708768 0,04617949 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02708768 0,04614729 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02886762 0,04914536 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02886762 0,04911113 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02886762 0,04907696 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02886762 0,04904283 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02886762 0,04900875 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02886762 0,04897471 ! bone remodeling GO:0046849 28 16 0,000 0,02886762 0,04894073 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02886762 0,04890679 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02886762 0,04887289 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02886762 0,04883905 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02886762 0,04880525 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02886762 0,0487715 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02886762 0,04873779 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02886762 0,04870413 ! startle response GO:0001964 28 16 0,000 0,02886762 0,04867052 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02886762 0,04863696 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02886762 0,04860344 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02886762 0,04856996 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02886762 0,04853654 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02886762 0,04850315 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02886762 0,04846982 ! pituitary gland development GO:0021983 30 16 0,000 0,02886762 0,04843653 ! response to osmotic stress GO:0006970 27 16 0,000 0,02886762 0,04840329 ! lysosomal transport GO:0007041 31 16 0,000 0,02886762 0,04837009 ! fructose metabolic process GO:0006000 25 16 0,000 0,02886762 0,04833693 ! L-amino acid transport GO:0015807 33 16 0,000 0,02886762 0,04830383 ! stem cell development GO:0048864 46 16 0,000 0,02886762 0,04827076 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02886762 0,04823775 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02886762 0,04820478 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02886762 0,04817185 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02886762 0,04813897 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02886762 0,04810613 ! axon cargo transport GO:0008088 46 16 0,000 0,02886762 0,04807334 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02886762 0,04804059 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02886762 0,04800789 ! DNA replication initiation GO:0006270 28 16 0,000 0,02886762 0,04797523 ! neuron recognition GO:0008038 40 16 0,000 0,02886762 0,04794262 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02886762 0,04791005 ! tissue regeneration GO:0042246 27 16 0,000 0,02886762 0,04787752 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02886762 0,04784504 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02886762 0,0478126 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02886762 0,04778021 ! biomineral formation GO:0031214 22 16 0,000 0,02886762 0,04774786 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02886762 0,04771555 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02886762 0,04768329 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02886762 0,04765107 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02886762 0,0476189 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02886762 0,04758677 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02886762 0,04755468 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02886762 0,04752263 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02886762 0,04749063 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02886762 0,04745867 ! peptide hormone processing GO:0016486 27 16 0,000 0,02886762 0,04742676 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03064434 0,05031192 ! metencephalon development GO:0022037 32 17 0,000 0,03064434 0,05027813 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03064434 0,05024439 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03064434 0,05021069 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03064434 0,05017703 ! signal complex assembly GO:0007172 47 17 0,000 0,03064434 0,05014343 ! filopodium assembly GO:0046847 42 17 0,000 0,03064434 0,05010986 ! endothelial cell migration GO:0043542 31 17 0,000 0,03064434 0,05007634 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03064434 0,05004287 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03064434 0,05000944 ! glial cell development GO:0021782 28 17 0,000 0,03064434 0,04997606 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03064434 0,04994272 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03064434 0,04990942 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03064434 0,04987617 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03064434 0,04984297 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03064434 0,0498098 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03064434 0,04977669 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03064434 0,04974361 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03064434 0,04971058 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03064434 0,04967759 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03064434 0,04964465 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03064434 0,04961175 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03064434 0,0495789 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03064434 0,04954609 ! membrane budding GO:0006900 42 17 0,000 0,03064434 0,04951332 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03064434 0,04948059 ! regulation of protein binding GO:0043393 33 17 0,000 0,03064434 0,04944791 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03064434 0,04941527 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03064434 0,04938267 ! genitalia development GO:0048806 32 17 0,000 0,03064434 0,04935012 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03064434 0,04931761 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03064434 0,04928514 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03064434 0,04925272 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03064434 0,04922034 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03064434 0,049188 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03064434 0,0491557 ! steroid catabolic process GO:0006706 34 17 0,000 0,03064434 0,04912345 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03064434 0,04909124 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03064434 0,04905907 ! gas transport GO:0015669 26 17 0,000 0,03064434 0,04902694 ! organic cation transport GO:0015695 32 17 0,000 0,03064434 0,04899485 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03064434 0,04896281 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03064434 0,04893081 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03064434 0,04889885 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,03241787 0,05169508 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03241787 0,05166136 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03241787 0,05162768 ! limbic system development GO:0021761 40 18 0,000 0,03241787 0,05159405 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03241787 0,05156046 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03241787 0,05152691 ! adult walking behavior GO:0007628 36 18 0,000 0,03241787 0,05149341 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03241787 0,05145995 ! heart looping GO:0001947 34 18 0,000 0,03241787 0,05142653 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03241787 0,05139316 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03241787 0,05135983 ! centrosome cycle GO:0007098 26 18 0,000 0,03241787 0,05132655 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03241787 0,0512933 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03241787 0,05126011 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03241787 0,05122695 ! glycine metabolic process GO:0006544 30 18 0,000 0,03241787 0,05119383 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03241787 0,05116076 ! response to retinoic acid GO:0032526 31 18 0,000 0,03241787 0,05112774 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,03241787 0,05109475 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03241787 0,05106181 ! DNA integration GO:0015074 32 18 0,000 0,03241787 0,05102891 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03241787 0,05099605 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03241787 0,05096323 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03241787 0,05093046 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03241787 0,05089773 ! neural crest cell migration GO:0001755 41 18 0,000 0,03241787 0,05086504 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03241787 0,05083239 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03241787 0,05079978 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03241787 0,05076722 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03241787 0,0507347 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03241787 0,05070222 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03241787 0,05066978 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03241787 0,05063738 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03241787 0,05060502 ! detection of bacterium GO:0016045 22 18 0,000 0,03241787 0,05057271 ! nerve development GO:0021675 34 18 0,000 0,03241787 0,05054044 ! defense response to virus GO:0051607 43 18 0,000 0,03241787 0,0505082 ! microspike assembly GO:0030035 46 18 0,000 0,03241787 0,05047601 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03241787 0,05044386 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03241787 0,05041175 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03418821 0,05313091 ! positive regulation of translation GO:0045727 31 19 0,000 0,03418821 0,05309713 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03418821 0,0530634 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03418821 0,05302971 ! neuron maturation GO:0042551 46 19 0,000 0,03418821 0,05299606 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03418821 0,05296245 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03418821 0,05292889 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03418821 0,05289537 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03418821 0,05286189 ! inositol metabolic process GO:0006020 33 19 0,000 0,03418821 0,05282845 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03418821 0,05279506 ! memory GO:0007613 34 19 0,000 0,03418821 0,05276171 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03418821 0,0527284 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03418821 0,05269513 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03418821 0,05266191 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03418821 0,05262872 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03418821 0,05259558 ! cerebral cortex development GO:0021987 40 19 0,000 0,03418821 0,05256248 ! pigmentation during development GO:0048066 42 19 0,000 0,03418821 0,05252942 ! response to vitamin A GO:0033189 32 19 0,000 0,03418821 0,05249641 ! heme metabolic process GO:0042168 40 19 0,000 0,03418821 0,05246343 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03418821 0,0524305 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03418821 0,05239761 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03418821 0,05236476 ! response to fungus GO:0009620 26 19 0,000 0,03418821 0,05233195 ! peptide cross-linking GO:0018149 39 19 0,000 0,03418821 0,05229918 ! protein export from nucleus GO:0006611 40 19 0,000 0,03418821 0,05226645 ! heart process GO:0003015 32 19 0,000 0,03418821 0,05223376 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03418821 0,05220112 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03418821 0,05216851 ! visual learning GO:0008542 38 19 0,000 0,03418821 0,05213595 ! cellular pigmentation GO:0033059 37 19 0,000 0,03418821 0,05210342 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03418821 0,05207094 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03418821 0,0520385 ! vitamin transport GO:0051180 31 19 0,000 0,03418821 0,05200609 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03418821 0,05197373 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03418821 0,05194141 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03418821 0,05190913 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03418821 0,05187689 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03418821 0,05184468 ! cilium assembly GO:0042384 38 19 0,000 0,03418821 0,05181252 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03418821 0,0517804 ! protein secretion GO:0009306 45 20 0,000 0,03595535 0,05442312 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03595535 0,05438942 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03595535 0,05435577 ! positive regulation of ossification GO:0045778 50 20 0,000 0,03595535 0,05432215 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03595535 0,05428858 ! skin development GO:0043588 42 20 0,000 0,03595535 0,05425504 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03595535 0,05422155 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03595535 0,0541881 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,03595535 0,0541547 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03595535 0,05412133 ! response to vitamin GO:0033273 36 20 0,000 0,03595535 0,054088 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03595535 0,05405472 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,03595535 0,05402147 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03595535 0,05398827 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03595535 0,05395511 ! response to alkaloid GO:0043279 38 20 0,000 0,03595535 0,05392199 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03595535 0,05388891 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,03595535 0,05385587 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03595535 0,05382287 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03595535 0,05378991 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03595535 0,05375699 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,03595535 0,05372411 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03595535 0,05369127 ! peptide secretion GO:0002790 38 20 0,000 0,03595535 0,05365847 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03595535 0,05362571 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,03595535 0,05359299 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03595535 0,05356031 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03595535 0,05352768 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03595535 0,05349508 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03595535 0,05346252 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03595535 0,05343 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03595535 0,05339752 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03595535 0,05336508 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,03595535 0,05333268 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03595535 0,05330031 ! regulation of glucose import GO:0046324 30 20 0,000 0,03595535 0,05326799 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03595535 0,05323571 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03595535 0,05320346 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03595535 0,05317126 ! negative regulation of translation GO:0017148 32 20 0,000 0,03595535 0,05313909 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03595535 0,05310696 ! regulation of cell killing GO:0031341 46 21 0,000 0,03771931 0,05567871 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,03771931 0,05564509 ! hormone secretion GO:0046879 39 21 0,000 0,03771931 0,05561151 ! cAMP metabolic process GO:0046058 41 21 0,000 0,03771931 0,05557797 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,03771931 0,05554447 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,03771931 0,05551101 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,03771931 0,05547759 ! ovarian follicle development GO:0001541 39 21 0,000 0,03771931 0,05544421 ! smooth muscle contraction GO:0006939 48 21 0,000 0,03771931 0,05541087 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,03771931 0,05537757 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,03771931 0,05534431 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,03771931 0,05531109 ! plasma membrane fusion GO:0045026 33 21 0,000 0,03771931 0,05527791 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,03771931 0,05524477 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,03771931 0,05521167 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,03771931 0,0551786 ! sensory perception of pain GO:0019233 33 21 0,000 0,03771931 0,05514558 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,03771931 0,0551126 ! diencephalon development GO:0021536 36 21 0,000 0,03771931 0,05507966 ! collagen fibril organization GO:0030199 62 21 0,000 0,03771931 0,05504676 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,03771931 0,05501389 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,03771931 0,05498107 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,03771931 0,05494828 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,03771931 0,05491554 ! collagen catabolic process GO:0030574 29 21 0,000 0,03771931 0,05488283 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,03771931 0,05485016 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,03771931 0,05481753 ! sperm-egg recognition GO:0035036 23 21 0,000 0,03771931 0,05478494 ! actin filament-based movement GO:0030048 47 21 0,000 0,03771931 0,05475239 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,03771931 0,05471988 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,03948009 0,05724027 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,03948009 0,05720632 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,03948009 0,05717241 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,03948009 0,05713854 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,03948009 0,05710471 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,03948009 0,05707092 ! microtubule-based transport GO:0010970 59 22 0,000 0,03948009 0,05703717 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,03948009 0,05700346 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,03948009 0,05696979 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,03948009 0,05693616 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,03948009 0,05690257 ! cellular response to starvation GO:0009267 37 22 0,000 0,03948009 0,05686902 ! vacuolar transport GO:0007034 41 22 0,000 0,03948009 0,05683551 ! central nervous system neuron development GO:0021954 47 22 0,000 0,03948009 0,05680204 ! fucose metabolic process GO:0006004 44 22 0,000 0,03948009 0,0567686 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,03948009 0,05673521 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,03948009 0,05670186 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,03948009 0,05666854 ! ureteric bud development GO:0001657 50 22 0,000 0,03948009 0,05663527 ! cell aging GO:0007569 48 22 0,000 0,03948009 0,05660203 ! stem cell differentiation GO:0048863 57 22 0,000 0,03948009 0,05656883 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,03948009 0,05653567 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,03948009 0,05650255 ! renal system process GO:0003014 42 22 0,000 0,03948009 0,05646947 ! vasodilation GO:0042311 40 22 0,000 0,03948009 0,05643643 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,03948009 0,05640343 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,03948009 0,05637046 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,03948009 0,05633753 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,03948009 0,05630465 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,03948009 0,0562718 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,03948009 0,05623899 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,03948009 0,05620621 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,03948009 0,05617348 ! sarcomere organization GO:0045214 32 22 0,000 0,03948009 0,05614078 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,03948009 0,05610812 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,03948009 0,0560755 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,03948009 0,05604292 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,03948009 0,05601037 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,03948009 0,05597786 ! gut development GO:0048565 44 22 0,000 0,03948009 0,05594539 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,03948009 0,05591296 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,03948009 0,05588057 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,03948009 0,05584821 ! protein stabilization GO:0050821 41 22 0,000 0,03948009 0,05581589 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,0412377 0,05826703 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,0412377 0,05823335 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,0412377 0,05819971 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,0412377 0,05816611 ! gluconeogenesis GO:0006094 38 23 0,000 0,0412377 0,05813254 ! glycerol metabolic process GO:0006071 40 23 0,000 0,0412377 0,05809902 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,0412377 0,05806553 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,0412377 0,05803208 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,0412377 0,05799868 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,0412377 0,0579653 ! regeneration GO:0031099 42 23 0,000 0,0412377 0,05793197 ! axis specification GO:0009798 43 23 0,000 0,0412377 0,05789868 ! visual behavior GO:0007632 46 23 0,000 0,0412377 0,05786542 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,0412377 0,0578322 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,0412377 0,05779902 ! response to ethanol GO:0045471 47 23 0,000 0,0412377 0,05776588 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,0412377 0,05773278 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,0412377 0,05769971 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,0412377 0,05766669 ! peroxisome organization GO:0007031 43 23 0,000 0,0412377 0,05763369 ! lysosome organization GO:0007040 47 23 0,000 0,0412377 0,05760074 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,0412377 0,05756783 ! vesicle targeting GO:0006903 49 23 0,000 0,0412377 0,05753495 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,0412377 0,05750211 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,0412377 0,05746931 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,0412377 0,05743654 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,0412377 0,05740382 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,0412377 0,05737113 ! DNA modification GO:0006304 36 23 0,000 0,0412377 0,05733847 ! fatty acid transport GO:0015908 47 23 0,000 0,0412377 0,05730586 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,0412377 0,05727328 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,0412377 0,05724074 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,0412377 0,05720823 ! hormone transport GO:0009914 41 23 0,000 0,0412377 0,05717577 ! cell-cell recognition GO:0009988 28 23 0,000 0,0412377 0,05714333 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,0412377 0,05711094 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,0412377 0,05707858 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,0412377 0,05704626 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,04299214 0,05943962 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,04299214 0,059406 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,04299214 0,05937241 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,04299214 0,05933887 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,04299214 0,05930537 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,04299214 0,0592719 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,04299214 0,05923847 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,04299214 0,05920507 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,04299214 0,05917172 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,04299214 0,0591384 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,04299214 0,05910512 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,04299214 0,05907188 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,04299214 0,05903867 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,04299214 0,05900551 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,04299214 0,05897238 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,04299214 0,05893928 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,04299214 0,05890623 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,04299214 0,05887321 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,04299214 0,05884022 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,04299214 0,05880728 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,04299214 0,05877437 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,04299214 0,0587415 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,04299214 0,05870866 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,04299214 0,05867587 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,04299214 0,05864311 ! membrane depolarization GO:0051899 45 24 0,000 0,04299214 0,05861038 ! pallium development GO:0021543 56 24 0,000 0,04299214 0,05857769 ! oogenesis GO:0048477 44 24 0,000 0,04299214 0,05854504 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,04299214 0,05851242 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,04299214 0,05847984 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,04299214 0,0584473 ! platelet activation GO:0030168 41 24 0,000 0,04299214 0,0584148 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,04299214 0,05838232 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,04299214 0,05834989 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,04299214 0,05831749 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,04299214 0,05828513 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,04299214 0,0582528 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,04299214 0,05822051 ! regulation of amine transport GO:0051952 41 24 0,000 0,04299214 0,05818826 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,04299214 0,05815604 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,04474342 0,06049152 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,04474342 0,06045807 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,04474342 0,06042464 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,04474342 0,06039126 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,04474342 0,06035791 ! leukocyte adhesion GO:0007159 55 25 0,000 0,04474342 0,0603246 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,04474342 0,06029133 ! phototransduction GO:0007602 37 25 0,000 0,04474342 0,06025809 ! keratinization GO:0031424 37 25 0,000 0,04474342 0,06022489 ! vasculogenesis GO:0001570 49 25 0,000 0,04474342 0,06019173 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,04474342 0,0601586 ! vacuole organization GO:0007033 49 25 0,000 0,04474342 0,06012551 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,04474342 0,06009246 ! receptor metabolic process GO:0043112 53 25 0,000 0,04474342 0,06005944 ! chromosome condensation GO:0030261 48 25 0,000 0,04474342 0,06002646 ! regulation of behavior GO:0050795 48 25 0,000 0,04474342 0,05999351 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,04474342 0,0599606 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,04474342 0,05992773 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,04474342 0,05989489 ! immunoglobulin production GO:0002377 62 25 0,000 0,04474342 0,05986209 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,04474342 0,05982933 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,04474342 0,0597966 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,04474342 0,0597639 ! liver development GO:0001889 55 25 0,000 0,04474342 0,05973125 ! protein tetramerization GO:0051262 57 25 0,000 0,04474342 0,05969862 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,04649155 0,06199719 ! myelination GO:0042552 50 26 0,000 0,04649155 0,06196337 ! initiation of viral infection GO:0019059 60 26 0,000 0,04649155 0,06192958 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,04649155 0,06189583 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,04649155 0,06186212 ! molting cycle process GO:0022404 52 26 0,000 0,04649155 0,06182844 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 0,000 0,04649155 0,06179481 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,04649155 0,0617612 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,04649155 0,06172764 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,04649155 0,06169411 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,04649155 0,06166062 ! digestive system process GO:0022600 49 26 0,000 0,04649155 0,06162716 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,04649155 0,06159374 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,04649155 0,06156035 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,04649155 0,06152701 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,04649155 0,06149369 ! neural crest cell development GO:0014032 59 26 0,000 0,04649155 0,06146042 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,04649155 0,06142718 ! negative regulation of cell development GO:0010721 83 26 0,000 0,04649155 0,06139397 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,04649155 0,06136081 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,04649155 0,06132767 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,04649155 0,06129458 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,04649155 0,06126152 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,04649155 0,06122849 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,04649155 0,0611955 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,04649155 0,06116255 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,04649155 0,06112963 ! blastocyst development GO:0001824 50 26 0,000 0,04649155 0,06109675 ! telomere organization GO:0032200 46 26 0,000 0,04649155 0,0610639 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,04649155 0,06103109 ! neural tube closure GO:0001843 58 26 0,000 0,04649155 0,06099831 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,04649155 0,06096557 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,04649155 0,06093286 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,04649155 0,06090019 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,04823652 0,06315211 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,04823652 0,06311828 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,04823652 0,06308449 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,04823652 0,06305074 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,04823652 0,06301702 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,04823652 0,06298334 ! iron ion transport GO:0006826 65 27 0,000 0,04823652 0,06294969 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,04823652 0,06291609 ! superoxide metabolic process GO:0006801 41 27 0,000 0,04823652 0,06288251 ! tube lumen formation GO:0035148 59 27 0,000 0,04823652 0,06284898 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,04823652 0,06281547 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,04823652 0,06278201 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,04823652 0,06274858 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,04823652 0,06271518 ! response to starvation GO:0042594 47 27 0,000 0,04823652 0,06268182 ! response to toxin GO:0009636 49 27 0,000 0,04823652 0,0626485 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,04823652 0,06261521 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,04823652 0,06258196 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,04823652 0,06254874 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,04823652 0,06251556 ! leukocyte proliferation GO:0070661 59 27 0,000 0,04823652 0,06248241 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,04823652 0,0624493 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,04997836 0,06467009 ! neuron fate commitment GO:0048663 52 28 0,000 0,04997836 0,06463585 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,04997836 0,06460165 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,04997836 0,06456749 ! protein amino acid acylation GO:0043543 59 28 0,000 0,04997836 0,06453336 ! vesicle docking GO:0048278 55 28 0,000 0,04997836 0,06449927 ! circadian rhythm GO:0007623 56 28 0,000 0,04997836 0,06446522 ! dendrite development GO:0016358 67 28 0,000 0,04997836 0,0644312 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,04997836 0,06439722 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,04997836 0,06436327 ! sperm motility GO:0030317 37 28 0,000 0,04997836 0,06432936 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,04997836 0,06429548 ! base-excision repair GO:0006284 41 28 0,000 0,04997836 0,06426164 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,04997836 0,06422784 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,04997836 0,06419407 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,04997836 0,06416034 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,04997836 0,06412664 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,04997836 0,06409298 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,04997836 0,06405935 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,04997836 0,06402576 ! glutathione metabolic process GO:0006749 42 28 0,000 0,04997836 0,0639922 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,04997836 0,06395868 ! lipid oxidation GO:0034440 48 28 0,000 0,04997836 0,0639252 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,04997836 0,06389174 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,04997836 0,06385833 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05171705 0,06604535 ! translational initiation GO:0006413 66 29 0,000 0,05171705 0,06601084 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05171705 0,06597637 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05171705 0,06594194 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05171705 0,06590754 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,05171705 0,06587317 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05171705 0,06583885 ! primary neural tube formation GO:0014020 61 29 0,000 0,05171705 0,06580456 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05171705 0,0657703 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05171705 0,06573608 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,05171705 0,0657019 ! somitogenesis GO:0001756 52 29 0,000 0,05171705 0,06566775 ! synaptogenesis GO:0007416 46 29 0,000 0,05171705 0,06563364 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05171705 0,06559956 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05171705 0,06556552 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05171705 0,06553151 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05171705 0,06549754 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,05345261 0,06766048 ! phenol metabolic process GO:0018958 56 30 0,000 0,05345261 0,06762544 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,05345261 0,06759044 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,05345261 0,06755547 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,05345261 0,06752054 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,05345261 0,06748564 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,05345261 0,06745079 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,05345261 0,06741596 ! acute-phase response GO:0006953 50 30 0,000 0,05345261 0,06738118 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,05345261 0,06734643 ! myofibril assembly GO:0030239 50 30 0,000 0,05345261 0,06731171 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,05345261 0,06727703 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,05345261 0,06724239 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,05345261 0,06720778 ! cell fate determination GO:0001709 64 30 0,000 0,05345261 0,06717321 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,05345261 0,06713867 ! phospholipid transport GO:0015914 65 30 0,000 0,05345261 0,06710417 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,05345261 0,06706971 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,05345261 0,06703528 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,05345261 0,06700088 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,05345261 0,06696652 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,05345261 0,0669322 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,05345261 0,06689791 ! regulation of coagulation GO:0050818 52 30 0,000 0,05345261 0,06686366 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,05518504 0,06899542 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,05518504 0,06896013 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,05518504 0,06892487 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,05518504 0,06888965 ! regulation of innate immune response GO:0045088 57 31 0,000 0,05518504 0,06885447 ! ovulation cycle process GO:0022602 55 31 0,000 0,05518504 0,06881932 ! peptide transport GO:0015833 60 31 0,000 0,05518504 0,06878421 ! male gonad development GO:0008584 56 31 0,000 0,05518504 0,06874913 ! iron ion homeostasis GO:0055072 60 31 0,000 0,05518504 0,06871409 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,05518504 0,06867909 ! detection of light stimulus GO:0009583 44 31 0,000 0,05518504 0,06864412 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,05518504 0,06860919 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,05518504 0,06857429 ! natural killer cell activation GO:0030101 50 31 0,000 0,05518504 0,06853943 ! ensheathment of neurons GO:0007272 64 31 0,000 0,05518504 0,0685046 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,05518504 0,06846981 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,05518504 0,06843505 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,05518504 0,06840033 ! eye morphogenesis GO:0048592 65 31 0,000 0,05518504 0,06836564 ! response to heat GO:0009408 54 31 0,000 0,05518504 0,06833099 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,05518504 0,06829638 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,05691435 0,07040089 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,05691435 0,07036526 ! collagen metabolic process GO:0032963 49 32 0,000 0,05691435 0,07032967 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,05691435 0,07029411 ! spindle organization GO:0007051 50 32 0,000 0,05691435 0,07025859 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,05691435 0,07022311 ! metanephros development GO:0001656 81 32 0,000 0,05691435 0,07018766 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,05691435 0,07015225 ! muscle cell development GO:0055001 52 32 0,000 0,05691435 0,07011687 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,05691435 0,07008153 ! ovulation cycle GO:0042698 57 32 0,000 0,05691435 0,07004622 ! peripheral nervous system development GO:0007422 68 32 0,000 0,05691435 0,07001095 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,05691435 0,06997572 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,05691435 0,06994052 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,05691435 0,06990536 ! gene silencing GO:0016458 71 32 0,000 0,05691435 0,06987023 ! regulation of pH GO:0006885 56 33 0,000 0,05864054 0,07195321 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,05864054 0,07191709 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,05864054 0,07188101 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,05864054 0,07184496 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,05864054 0,07180894 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,05864054 0,07177297 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,05864054 0,07173703 ! response to ionizing radiation GO:0010212 74 33 0,000 0,05864054 0,07170112 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,05864054 0,07166525 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,05864054 0,07162942 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,05864054 0,07159363 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,05864054 0,07155786 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,05864054 0,07152214 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,05864054 0,07148645 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,05864054 0,0714508 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06036362 0,07351363 ! glial cell differentiation GO:0010001 67 34 0,000 0,06036362 0,073477 ! post-embryonic development GO:0009791 76 34 0,000 0,06036362 0,07344041 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06036362 0,07340385 ! cholesterol transport GO:0030301 62 34 0,000 0,06036362 0,07336733 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06036362 0,07333085 ! spliceosome assembly GO:0000245 75 34 0,000 0,06036362 0,0732944 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06036362 0,07325799 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,06036362 0,07322162 ! cell fate specification GO:0001708 56 34 0,000 0,06036362 0,07318528 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,06036362 0,07314897 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06036362 0,07311271 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06036362 0,07307648 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,0620836 0,07512146 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0620836 0,07508428 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0620836 0,07504712 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0620836 0,07501001 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0620836 0,07497293 ! membrane docking GO:0022406 69 35 0,000 0,0620836 0,07493589 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0620836 0,07489888 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0620836 0,07486191 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0620836 0,07482498 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0620836 0,07478808 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0620836 0,07475123 ! telencephalon development GO:0021537 81 35 0,000 0,0620836 0,0747144 ! sterol transport GO:0015918 63 35 0,000 0,0620836 0,07467761 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,0620836 0,07464086 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0620836 0,07460415 ! placenta development GO:0001890 53 35 0,000 0,0620836 0,07456747 ! vesicle localization GO:0051648 70 35 0,000 0,0620836 0,07453083 ! regulation of muscle development GO:0048634 82 36 0,000 0,06380048 0,07655431 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,06380048 0,07651672 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,06380048 0,07647918 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,06380048 0,07644167 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,06380048 0,0764042 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,06380048 0,07636676 ! positive regulation of cell development GO:0010720 85 36 0,000 0,06380048 0,07632937 ! protein targeting to membrane GO:0006612 75 36 0,000 0,06380048 0,076292 ! regulation of proteolysis GO:0030162 77 36 0,000 0,06380048 0,07625468 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,06380048 0,07621739 ! aerobic respiration GO:0009060 56 36 0,000 0,06380048 0,07618014 ! cytokine production GO:0001816 68 36 0,000 0,06380048 0,07614292 ! embryonic organ development GO:0048568 67 36 0,000 0,06380048 0,07610574 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,06380048 0,0760686 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,06380048 0,0760315 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,06551426 0,07803576 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,06551426 0,07799773 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,06551426 0,07795973 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,06551426 0,07792178 ! sister chromatid segregation GO:0000819 65 37 0,000 0,06551426 0,07788386 ! odontogenesis GO:0042476 74 37 0,000 0,06551426 0,07784598 ! actomyosin structure organization GO:0031032 68 37 0,000 0,06551426 0,07780814 ! tissue remodeling GO:0048771 78 37 0,000 0,06551426 0,07777033 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,06551426 0,07773256 ! female gonad development GO:0008585 71 37 0,000 0,06551426 0,07769482 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,06551426 0,07765712 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,06551426 0,07761946 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,06551426 0,07758184 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,06722495 0,07956907 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,06722495 0,07953054 ! meiosis I GO:0007127 74 38 0,000 0,06722495 0,07949204 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,06722495 0,07945358 ! organic anion transport GO:0015711 82 38 0,000 0,06722495 0,07941516 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,06722495 0,07937678 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,06722495 0,07933843 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,06722495 0,07930012 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,06722495 0,07926185 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,06722495 0,07922362 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,06722495 0,07918542 ! regulation of protein stability GO:0031647 77 38 0,000 0,06722495 0,07914726 ! spermatid development GO:0007286 69 38 0,000 0,06722495 0,07910913 ! pigment metabolic process GO:0042440 87 38 0,000 0,06722495 0,07907104 ! neural tube formation GO:0001841 79 38 0,000 0,06722495 0,07903299 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,06893256 0,08100156 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,06893256 0,08096262 ! negative regulation of binding GO:0051100 71 39 0,000 0,06893256 0,08092371 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,06893256 0,08088484 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,06893256 0,08084601 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,06893256 0,08080722 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,06893256 0,08076846 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,06893256 0,08072974 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,06893256 0,08069106 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,06893256 0,08065242 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07063709 0,08260719 ! learning GO:0007612 82 40 0,000 0,07063709 0,08256766 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07063709 0,08252818 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,07063709 0,08248873 ! lipid homeostasis GO:0055088 75 40 0,000 0,07063709 0,08244932 ! mismatch repair GO:0006298 58 40 0,000 0,07063709 0,08240994 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,07063709 0,0823706 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,07063709 0,08233131 ! RNA export from nucleus GO:0006405 61 41 0,000 0,07233855 0,08427424 ! mRNA catabolic process GO:0006402 79 41 0,000 0,07233855 0,08423407 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,07233855 0,08419394 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,07233855 0,08415385 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,07233855 0,08411379 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,07233855 0,08407378 ! gliogenesis GO:0042063 91 41 0,000 0,07233855 0,0840338 ! feeding behavior GO:0007631 69 41 0,000 0,07233855 0,08399386 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,07233855 0,08395396 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,07233855 0,08391409 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,07233855 0,08387427 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,07233855 0,08383448 ! spermatid differentiation GO:0048515 73 41 0,000 0,07233855 0,08379473 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,07233855 0,08375501 ! RNA modification GO:0009451 64 41 0,000 0,07233855 0,08371534 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,07403694 0,08564027 ! ear morphogenesis GO:0042471 64 42 0,000 0,07403694 0,08559974 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,07403694 0,08555925 ! T cell differentiation GO:0030217 93 42 0,000 0,07403694 0,08551879 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,07403694 0,08547838 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,07403694 0,085438 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,07403694 0,08539766 ! regulation of protein secretion GO:0050708 77 42 0,000 0,07403694 0,08535736 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,07403694 0,0853171 ! cytokinesis GO:0000910 84 42 0,000 0,07403694 0,08527687 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,07403694 0,08523669 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,07573227 0,08714741 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,07573227 0,08710638 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,07573227 0,08706538 ! regulation of tube size GO:0035150 76 43 0,000 0,07573227 0,08702443 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,07573227 0,08698352 ! glucose transport GO:0015758 66 43 0,000 0,07573227 0,08694264 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,07573227 0,0869018 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,07573227 0,08686101 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,07573227 0,08682024 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,07573227 0,08677952 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,07573227 0,08673884 ! segmentation GO:0035282 78 43 0,000 0,07573227 0,08669819 ! ion transmembrane transport GO:0034220 79 43 0,000 0,07573227 0,08665758 ! neuron migration GO:0001764 85 43 0,000 0,07573227 0,08661701 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,07573227 0,08657648 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,07742455 0,08846968 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,07742455 0,08842832 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,07742455 0,08838699 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,07742455 0,08834571 ! hexose transport GO:0008645 68 44 0,000 0,07742455 0,08830447 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,07742455 0,08826326 ! striated muscle contraction GO:0006941 85 44 0,000 0,07742455 0,08822209 ! phagocytosis GO:0006909 105 44 0,000 0,07742455 0,08818096 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,07742455 0,08813987 ! double-strand break repair GO:0006302 85 44 0,000 0,07742455 0,08809882 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,07911377 0,08997902 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,07911377 0,08993715 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,07911377 0,08989532 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,07911377 0,08985353 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,07911377 0,08981177 ! biopolymer methylation GO:0043414 91 45 0,000 0,07911377 0,08977006 ! B cell differentiation GO:0030183 124 45 0,000 0,07911377 0,08972838 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,07911377 0,08968675 ! female gamete generation GO:0007292 71 45 0,000 0,07911377 0,08964515 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,07911377 0,08960359 ! polyol metabolic process GO:0019751 77 45 0,000 0,07911377 0,08956207 ! developmental growth GO:0048589 88 45 0,000 0,07911377 0,08952058 ! maintenance of location in cell GO:0051651 101 45 0,000 0,07911377 0,08947914 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,08079995 0,09134395 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,08079995 0,0913017 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,08079995 0,09125949 ! glycolysis GO:0006096 71 46 0,000 0,08079995 0,09121731 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,08079995 0,09117518 ! leukocyte migration GO:0050900 75 46 0,000 0,08079995 0,09113309 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,08079995 0,09109103 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,08079995 0,09104902 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,08079995 0,09100704 ! pigmentation GO:0043473 103 46 0,000 0,08079995 0,0909651 ! cell growth GO:0016049 90 46 0,000 0,08079995 0,0909232 ! neural tube development GO:0021915 91 47 0,000 0,08248308 0,09277448 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,08248308 0,09273179 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,08416319 0,09457712 ! positive regulation of defense response GO:0031349 88 48 0,000 0,08416319 0,09453364 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,08416319 0,09449019 ! mitochondrial transport GO:0006839 94 48 0,000 0,08416319 0,09444679 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,08416319 0,09440343 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,08416319 0,0943601 ! endosome transport GO:0016197 127 48 0,000 0,08416319 0,09431682 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,08416319 0,09427357 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,08416319 0,09423037 ! male sex differentiation GO:0046661 93 48 0,000 0,08416319 0,0941872 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,08416319 0,09414408 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,08416319 0,09410099 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,08416319 0,09405794 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,08416319 0,09401493 ! methylation GO:0032259 97 48 0,000 0,08416319 0,09397197 ! response to calcium ion GO:0051592 94 49 0,000 0,08584026 0,09580071 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,08584026 0,09575696 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,08584026 0,09571326 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,08584026 0,0956696 ! JNK cascade GO:0007254 106 49 0,000 0,08584026 0,09562597 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,08584026 0,09558238 ! regulation of action potential GO:0001508 102 50 0,000 0,08751431 0,09740203 ! regulation of ion transport GO:0043269 86 50 0,000 0,08751431 0,09735768 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,08751431 0,09731336 ! endocrine system development GO:0035270 109 50 0,000 0,08751431 0,09726909 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,08751431 0,09722485 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,08751431 0,09718066 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,08751431 0,09713651 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,08751431 0,0970924 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,08751431 0,09704832 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,08918534 0,09885653 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,08918534 0,09881169 ! peptide metabolic process GO:0006518 80 51 0,000 0,08918534 0,0987669 ! response to temperature stimulus GO:0009266 84 51 0,000 0,08918534 0,09872215 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,08918534 0,09867744 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,08918534 0,09863277 ! positive regulation of binding GO:0051099 88 52 0,000 0,09085336 0,10043201 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,09085336 0,10038659 ! Notch signaling pathway GO:0007219 111 52 0,000 0,09085336 0,10034121 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,09085336 0,10029587 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,09085336 0,10025056 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,09085336 0,10020531 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,09085336 0,10016009 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,09085336 0,10011491 ! histone modification GO:0016570 104 52 0,000 0,09085336 0,10006977 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,09085336 0,10002467 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,09085336 0,09997962 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,09085336 0,0999346 ! amino acid activation GO:0043038 98 52 0,000 0,09085336 0,09988963 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,09251837 0,10167448 ! positive regulation of growth GO:0045927 96 53 0,000 0,09251837 0,10162876 ! inner ear development GO:0048839 89 53 0,000 0,09251837 0,10158309 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,09251837 0,10153745 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,09251837 0,10149186 ! vesicle organization GO:0016050 127 53 0,000 0,09251837 0,10144631 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,09251837 0,10140079 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,09251837 0,10135532 ! cartilage development GO:0051216 99 53 0,000 0,09251837 0,10130989 ! synapse organization GO:0050808 102 53 0,000 0,09251837 0,1012645 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,09418037 0,10303746 ! regulation of translational initiation GO:0006446 87 54 0,000 0,09418037 0,10299134 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,09418037 0,10294526 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,09418037 0,10289922 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,09418037 0,10285322 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,09418037 0,10280726 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,09418037 0,10276135 ! membrane fusion GO:0006944 122 54 0,000 0,09418037 0,10271547 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,09418037 0,10266964 ! covalent chromatin modification GO:0016569 115 54 0,000 0,09418037 0,10262384 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,09418037 0,10257809 ! regulation of cell shape GO:0008360 142 54 0,000 0,09418037 0,10253238 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,09418037 0,10248671 ! RNA catabolic process GO:0006401 103 55 0,000 0,09583938 0,1042456 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,09583938 0,10419921 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,09583938 0,10415285 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,09583938 0,10410654 ! cell recognition GO:0008037 98 55 0,000 0,09583938 0,10406027 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,09583938 0,10401405 ! cell maturation GO:0048469 107 55 0,000 0,09583938 0,10396786 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,09583938 0,10392171 ! response to UV GO:0009411 120 55 0,000 0,09583938 0,10387561 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,0974954 0,10562362 ! glucose catabolic process GO:0006007 88 56 0,000 0,0974954 0,1055768 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,0974954 0,10553003 ! RNA elongation GO:0006354 90 56 0,000 0,0974954 0,10548329 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,09914843 0,10722427 ! chloride transport GO:0006821 102 57 0,000 0,09914843 0,10717683 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,09914843 0,10712942 ! heart morphogenesis GO:0003007 105 57 0,000 0,09914843 0,10708206 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,09914843 0,10703474 ! regulation of actin filament length GO:0030832 118 58 0,000 0,10079849 0,10876798 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,10079849 0,10871996 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,10079849 0,10867198 ! aging GO:0007568 112 58 0,000 0,10079849 0,10862404 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,10079849 0,10857615 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,10079849 0,10852829 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,10079849 0,10848048 ! maintenance of location GO:0051235 124 58 0,000 0,10079849 0,10843272 ! nuclear export GO:0051168 110 59 0,000 0,10244556 0,11015603 ! establishment of organelle localization GO:0051656 122 59 0,000 0,10244556 0,11010757 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,10408966 0,11182544 ! DNA catabolic process GO:0006308 94 60 0,000 0,10408966 0,11177629 ! regulation of endocytosis GO:0030100 104 60 0,000 0,10408966 0,11172718 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,10408966 0,11167811 ! adult behavior GO:0030534 104 60 0,000 0,10408966 0,11162908 ! kidney development GO:0001822 133 60 0,000 0,10408966 0,1115801 ! regulation of cellular component size GO:0032535 125 61 0,000 0,1057308 0,11328963 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,1057308 0,11323996 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,1057308 0,11319034 ! regulation of heart contraction GO:0008016 123 61 0,000 0,1057308 0,11314076 ! camera-type eye development GO:0043010 126 61 0,000 0,1057308 0,11309122 ! proton transport GO:0015992 117 61 0,000 0,1057308 0,11304173 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,1057308 0,11299228 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,10736898 0,1146928 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,10736898 0,11464267 ! tRNA processing GO:0008033 102 62 0,000 0,10736898 0,11459258 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,10736898 0,11454254 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,10900421 0,11623626 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,10900421 0,11618555 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,10900421 0,11613488 ! hydrogen transport GO:0006818 121 64 0,000 0,11063648 0,11782255 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,11063648 0,11777121 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,11226581 0,11945356 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,11226581 0,11940156 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,11226581 0,1193496 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,11226581 0,11929768 ! ear development GO:0043583 114 66 0,000 0,1138922 0,12097333 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,1138922 0,12092075 ! gonad development GO:0008406 115 66 0,000 0,1138922 0,12086822 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,11551566 0,12253789 ! activation of MAPK activity GO:0000187 124 67 0,000 0,11551566 0,1224847 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,11551566 0,12243156 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,11551566 0,12237847 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,11551566 0,12232542 ! secondary metabolic process GO:0019748 125 67 0,000 0,11551566 0,12227242 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,11551566 0,12221947 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,11713619 0,12388039 ! hexose catabolic process GO:0019320 113 68 0,000 0,11713619 0,12382679 ! extracellular matrix organization GO:0030198 146 68 0,000 0,11713619 0,12377323 ! detection of external stimulus GO:0009581 102 68 0,000 0,11713619 0,12371972 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,11713619 0,12366625 ! regulation of lipase activity GO:0060191 137 68 0,000 0,11713619 0,12361283 ! cell projection assembly GO:0030031 138 68 0,000 0,11713619 0,12355946 ! negative regulation of cell size GO:0045792 144 69 0,000 0,11875379 0,1252117 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,11875379 0,12515768 ! lung development GO:0030324 165 69 0,000 0,11875379 0,12510371 ! urogenital system development GO:0001655 149 69 0,000 0,11875379 0,12504979 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,11875379 0,12499591 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,11875379 0,12494208 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,11875379 0,1248883 ! developmental maturation GO:0021700 128 69 0,000 0,11875379 0,12483456 ! single fertilization GO:0007338 83 69 0,000 0,11875379 0,12478087 ! germ cell development GO:0007281 133 70 0,000 0,12036848 0,12642313 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,12198025 0,12806092 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,12198025 0,12800591 ! appendage morphogenesis GO:0035107 150 72 0,000 0,12358912 0,12963856 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,12358912 0,12958292 ! respiratory tube development GO:0030323 171 72 0,000 0,12358912 0,12952733 ! B cell activation GO:0042113 179 72 0,000 0,12358912 0,12947179 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,12358912 0,12941629 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,12358912 0,12936085 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,12358912 0,12930544 ! appendage development GO:0048736 151 73 0,000 0,12519508 0,13092961 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,12519508 0,13087359 ! regulation of immune effector process GO:0002697 156 73 0,000 0,12519508 0,13081761 ! amino acid transport GO:0006865 148 74 0,000 0,12679814 0,13243603 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,12679814 0,13237943 ! respiratory system development GO:0060541 175 74 0,000 0,12679814 0,13232288 ! organelle localization GO:0051640 155 74 0,000 0,12679814 0,13226638 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,12839832 0,1338784 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,12839832 0,13382128 ! reproductive structure development GO:0048608 131 75 0,000 0,12839832 0,13376422 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,12839832 0,1337072 ! eye development GO:0001654 155 75 0,000 0,12839832 0,13365023 ! axon guidance GO:0007411 162 75 0,000 0,12839832 0,13359331 ! rhythmic process GO:0048511 142 75 0,000 0,12839832 0,13353644 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,1299956 0,13514011 ! learning or memory GO:0007611 161 76 0,000 0,1299956 0,13508263 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,1299956 0,13502519 ! regulation of blood pressure GO:0008217 134 76 0,000 0,1299956 0,13496781 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,1299956 0,13491047 ! amine catabolic process GO:0009310 136 77 0,000 0,13159001 0,13650717 ! neurotransmitter transport GO:0006836 142 77 0,000 0,13159001 0,13644923 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,13159001 0,13639134 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,13159001 0,1363335 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,13159001 0,1362757 ! regulation of catabolic process GO:0009894 173 77 0,000 0,13159001 0,13621796 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,13318153 0,13780707 ! antigen processing and presentation GO:0019882 117 78 0,000 0,13318153 0,13774872 ! fertilization GO:0009566 99 78 0,000 0,13318153 0,13769043 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,13318153 0,13763218 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,13477019 0,13921504 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,13477019 0,1391562 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,13477019 0,13909741 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,13477019 0,13903867 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,13635597 0,1406153 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,13635597 0,14055597 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,13635597 0,14049669 ! meiosis GO:0007126 143 81 0,000 0,1379389 0,14206776 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 0,000 0,1379389 0,14200789 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,1379389 0,14194807 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,1379389 0,14188831 ! protein import into nucleus GO:0006606 174 82 0,000 0,13951897 0,14345321 ! meiotic cell cycle GO:0051321 144 82 0,000 0,13951897 0,14339286 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,14109618 0,14495289 ! exocytosis GO:0006887 153 83 0,000 0,14109618 0,14489196 ! response to drug GO:0042493 149 83 0,000 0,14109618 0,14483108 ! response to oxygen levels GO:0070482 183 83 0,000 0,14109618 0,14477025 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,14109618 0,14470948 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,14109618 0,14464875 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,14109618 0,14458808 ! nuclear import GO:0051170 177 83 0,000 0,14109618 0,14452745 ! inorganic anion transport GO:0015698 156 83 0,000 0,14109618 0,14446688 ! response to metal ion GO:0010038 158 84 0,000 0,14267055 0,14601766 ! T cell activation GO:0042110 189 84 0,000 0,14267055 0,14595652 ! response to nutrient GO:0007584 135 84 0,000 0,14267055 0,14589542 ! digestion GO:0007586 130 84 0,000 0,14267055 0,14583438 ! negative regulation of transport GO:0051051 164 85 0,000 0,14424208 0,14737909 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,14424208 0,14731748 ! negative regulation of growth GO:0045926 168 85 0,000 0,14424208 0,14725592 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,14424208 0,14719441 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,14424208 0,14713295 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,14424208 0,14707154 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,14581077 0,14860898 ! regulation of lyase activity GO:0051339 169 86 0,000 0,14581077 0,14854701 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,14581077 0,14848509 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,14737664 0,15001713 ! mitochondrion organization GO:0007005 159 87 0,000 0,14737664 0,14995465 ! alcohol catabolic process GO:0046164 142 87 0,000 0,14737664 0,14989222 ! cellular respiration GO:0045333 143 88 0,000 0,14893967 0,1514189 ! amine biosynthetic process GO:0009309 146 88 0,000 0,14893967 0,15135591 ! sensory perception of smell GO:0007608 117 88 0,000 0,14893967 0,15129298 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,14893967 0,1512301 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,15049988 0,15275082 ! regulation of DNA binding GO:0051101 167 89 0,000 0,15049988 0,15268738 ! tube morphogenesis GO:0035239 194 89 0,000 0,15049988 0,152624 ! cellular defense response GO:0006968 123 89 0,000 0,15049988 0,15256067 ! protein localization in nucleus GO:0034504 192 89 0,000 0,15049988 0,15249739 ! regulation of neurological system process GO:0031644 175 89 0,000 0,15049988 0,15243417 ! response to inorganic substance GO:0010035 173 90 0,000 0,15205728 0,15394776 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,15205728 0,15388398 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,15205728 0,15382026 ! response to unfolded protein GO:0006986 139 90 0,000 0,15205728 0,1537566 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,15361187 0,15526429 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,15361187 0,15520008 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,15516365 0,15670309 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,15671262 0,15820204 ! amine transport GO:0015837 181 93 0,000 0,15671262 0,1581367 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,15671262 0,1580714 ! vitamin metabolic process GO:0006766 153 93 0,000 0,15671262 0,15800617 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,1582588 0,15949928 ! female pregnancy GO:0007565 166 94 0,000 0,1582588 0,15943351 ! sterol metabolic process GO:0016125 166 94 0,000 0,1582588 0,15936779 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,1582588 0,15930213 ! regulation of membrane potential GO:0042391 179 94 0,000 0,1582588 0,15923652 ! regulation of defense response GO:0031347 171 95 0,000 0,15980219 0,16072325 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,15980219 0,1606571 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,15980219 0,16059102 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,15980219 0,16052498 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,15980219 0,16045901 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,15980219 0,16039308 ! sex differentiation GO:0007548 171 96 0,000 0,1613428 0,16187288 ! response to protein stimulus GO:0051789 158 96 0,000 0,1613428 0,16180643 ! regulation of T cell activation GO:0050863 175 96 0,000 0,1613428 0,16174003 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,16288062 0,16321467 ! leukocyte differentiation GO:0002521 232 98 0,000 0,16441567 0,16468531 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,16441567 0,16461782 ! forebrain development GO:0030900 210 98 0,000 0,16441567 0,16455038 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,16441567 0,16448299 ! hormone metabolic process GO:0042445 171 100 0,000 0,16747745 0,16747745