pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1227-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of microtubule polymerization GO:0031116 13 6 2,000 1,497E-07 3,602E-04 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 2,000 2,616E-07 3,147E-04 ! regulation of microtubule polymerization GO:0031113 15 7 2,000 2,616E-07 2,098E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 8,931E-07 5,372E-04 ! positive regulation of protein polymerization GO:0032273 25 13 2,000 2,12E-06 1,02E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 3,362E-06 1,348E-03 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 2,000 4,132E-06 1,42E-03 ! positive regulation of protein complex assembly GO:0031334 32 17 2,000 5,011E-06 1,507E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 8,365E-06 2,236E-03 ! positive regulation of cytoskeleton organization GO:0051495 48 22 2,000 1,127E-05 2,711E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 1,127E-05 2,465E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 1,676E-05 3,36E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 1,892E-05 3,501E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 2,647E-05 4,549E-03 ! transepithelial chloride transport GO:0030321 9 5 1,000 3,888E-05 6,236E-03 GO:0070633|transepithelial transport, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,888E-05 5,847E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 3,888E-05 5,503E-03 ! regulation of microtubule-based process GO:0032886 78 35 2,000 4,701E-05 6,284E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 5,122E-05 6,485E-03 ! mammary gland development GO:0030879 86 39 2,000 6,528E-05 7,853E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 7,047E-05 8,074E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 8,144E-05 8,906E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 8,144E-05 8,519E-03 ! vesicle fusion GO:0006906 17 7 1,000 8,144E-05 8,164E-03 ! epithelial cell differentiation GO:0030855 79 43 2,000 8,765E-05 8,435E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,084E-04 0,01003524 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,084E-04 9,664E-03 ! protein homooligomerization GO:0051260 76 47 2,000 1,145E-04 9,84E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,392E-04 0,01155288 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,392E-04 0,01116778 ! gas homeostasis GO:0033483 16 9 1,000 1,392E-04 0,01080753 ! induction of an organ GO:0001759 14 9 1,000 1,392E-04 0,01046979 ! regulation of protein polymerization GO:0032271 103 53 2,000 1,64E-04 0,01195978 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,738E-04 0,01230161 ! localization within membrane GO:0051668 20 10 1,000 1,738E-04 0,01195013 ! positive regulation of organelle organization GO:0010638 100 56 2,000 1,933E-04 0,0129177 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,122E-04 0,0137985 ! developmental induction GO:0031128 19 11 1,000 2,122E-04 0,01343538 GO:0045168|cell-cell signaling involved in cell fate specification, ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 2,373E-04 0,01463698 ! regulation of protein complex assembly GO:0043254 117 61 2,000 2,492E-04 0,01498799 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,492E-04 0,01462243 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,543E-04 0,01456828 ! gland morphogenesis GO:0022612 29 12 1,000 2,543E-04 0,01422948 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,742E-04 0,01499169 ! lipid localization GO:0010876 28 13 1,000 3,002E-04 0,01604865 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 3,002E-04 0,01569976 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,002E-04 0,01536572 ! lung development GO:0030324 144 67 2,000 3,289E-04 0,01648446 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 3,436E-04 0,01686947 ! lactation GO:0007595 26 14 1,000 3,497E-04 0,01682947 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 1,000 3,497E-04 0,01649948 ! respiratory tube development GO:0030323 150 70 2,000 3,742E-04 0,01731387 ! regulation of vasodilation GO:0042312 26 15 1,000 4,03E-04 0,01829597 ! respiratory system development GO:0060541 153 72 2,000 4,065E-04 0,01811375 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,6E-04 0,02012351 ! protein oligomerization GO:0051259 139 78 2,000 5,142E-04 0,0220923 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 5,207E-04 0,02197821 ! regulation of peptidase activity GO:0052547 134 79 2,000 5,337E-04 0,02214118 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,85E-04 0,02385672 ! lipid phosphorylation GO:0046834 35 19 1,000 6,53E-04 0,02618541 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 7,246E-04 0,02858128 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 7,246E-04 0,02812029 ! gland development GO:0048732 206 88 2,000 7,313E-04 0,02792894 ! inactivation of MAPK activity GO:0000188 39 21 1,000 7,999E-04 0,0300705 ! vasodilation GO:0042311 39 21 1,000 7,999E-04 0,02960788 ! regulation of vasoconstriction GO:0019229 39 21 1,000 7,999E-04 0,02915927 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 8,787E-04 0,031556 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 8,787E-04 0,03109194 ! vesicle docking GO:0048278 47 24 1,000 1,047E-03 0,03651673 ! membrane depolarization GO:0051899 39 24 1,000 1,047E-03 0,03599507 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,047E-03 0,03548809 ! vasculogenesis GO:0001570 46 25 1,000 1,137E-03 0,03798957 ! sperm motility GO:0030317 31 25 1,000 1,137E-03 0,03746917 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 1,137E-03 0,03696283 ! regulation of blood coagulation GO:0030193 40 25 1,000 1,137E-03 0,03646999 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,23E-03 0,03893939 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,23E-03 0,03843369 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 1,23E-03 0,03794095 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,327E-03 0,04040576 ! regulation of coagulation GO:0050818 46 29 1,000 1,531E-03 0,0460349 ! membrane docking GO:0022406 61 30 1,000 1,638E-03 0,04865187 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 1,638E-03 0,04805855 ! cholesterol homeostasis GO:0042632 53 31 1,000 1,749E-03 0,05068907 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 1,000 1,749E-03 0,05008562 ! cholesterol transport GO:0030301 56 32 1,000 1,863E-03 0,05272862 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 1,863E-03 0,0521155 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 1,863E-03 0,05151647 ! cell fate specification GO:0001708 52 33 1,000 1,98E-03 0,0541476 ! sterol transport GO:0015918 57 33 1,000 1,98E-03 0,0535392 ! neutral lipid metabolic process GO:0006638 50 35 1,000 2,226E-03 0,05951018 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 2,226E-03 0,05885622 ! tissue remodeling GO:0048771 76 37 1,000 2,485E-03 0,06499686 ! glycerol ether metabolic process GO:0006662 53 37 1,000 2,485E-03 0,06429797 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 2,485E-03 0,06361395 ! lipid homeostasis GO:0055088 67 38 1,000 2,62E-03 0,06635634 ! organic ether metabolic process GO:0018904 55 39 1,000 2,758E-03 0,06912616 ! Rho protein signal transduction GO:0007266 74 39 1,000 2,758E-03 0,06841352 ! regulation of tube size GO:0035150 71 42 1,000 3,193E-03 0,07838037 GO:0050880|regulation of blood vessel size, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 3,193E-03 0,07758865 ! neuron migration GO:0001764 79 42 1,000 3,193E-03 0,07681276 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 3,344E-03 0,07966026 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 3,657E-03 0,08625827 ! cell growth GO:0016049 84 45 1,000 3,657E-03 0,08542081 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 3,818E-03 0,08833199 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 3,818E-03 0,08749074 ! response to insulin stimulus GO:0032868 95 46 1,000 3,818E-03 0,08666535 ! positive regulation of protein transport GO:0051222 72 46 1,000 3,818E-03 0,0858554 ! vascular process in circulatory system GO:0003018 80 47 1,000 3,983E-03 0,08872752 ! positive regulation of cell cycle GO:0045787 89 48 1,000 4,151E-03 0,09161878 ! response to estrogen stimulus GO:0043627 93 51 1,000 4,674E-03 0,10222479 ! vesicle organization GO:0016050 107 51 1,000 4,674E-03 0,10130385 ! regulation of muscle contraction GO:0006937 81 52 1,000 4,854E-03 0,10428216 ! membrane fusion GO:0006944 110 52 1,000 4,854E-03 0,10335931 ! response to UV GO:0009411 104 53 1,000 5,038E-03 0,10633463 ! activation of phospholipase C activity GO:0007202 103 54 1,000 5,225E-03 0,10932465 GO:0010863|positive regulation of phospholipase C activity, ! chloride transport GO:0006821 90 55 1,000 5,416E-03 0,11232871 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 5,416E-03 0,11136864 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 5,806E-03 0,11837649 ! positive regulation of cell migration GO:0030335 126 57 1,000 5,806E-03 0,11738173 ! lipid modification GO:0030258 97 57 1,000 5,806E-03 0,11640354 ! regulation of phospholipase activity GO:0010517 106 57 1,000 5,806E-03 0,11544153 ! regulation of intracellular transport GO:0032386 101 57 1,000 5,806E-03 0,11449529 ! positive regulation of lipase activity GO:0060193 108 58 1,000 6,005E-03 0,11747043 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 7,05E-03 0,13679611 ! multicellular organism reproduction GO:0032504 111 64 1,000 7,268E-03 0,13990086 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 1,000 7,268E-03 0,13879054 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 7,941E-03 0,15044075 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 7,941E-03 0,14926543 ! negative regulation of kinase activity GO:0033673 131 68 1,000 8,171E-03 0,15240229 ! regulation of lipase activity GO:0060191 130 68 1,000 8,171E-03 0,15122997 ! cAMP-mediated signaling GO:0019933 120 69 1,000 8,404E-03 0,15435877 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 8,88E-03 0,16185327 ! regulation of caspase activity GO:0043281 122 72 1,000 9,122E-03 0,16501581 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 9,122E-03 0,16378435 ! negative regulation of transferase activity GO:0051348 140 72 1,000 9,122E-03 0,16257113 ! axon guidance GO:0007411 139 73 1,000 9,367E-03 0,16571057 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 9,615E-03 0,16885552 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 9,922E-03 0,17299135 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 9,922E-03 0,17174681 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,922E-03 0,17052004 ! positive regulation of helicase activity GO:0051096 11 5 0,000 9,922E-03 0,16931068 ! neuron fate determination GO:0048664 7 5 0,000 9,922E-03 0,16811835 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,922E-03 0,1669427 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 9,922E-03 0,16578337 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 9,922E-03 0,16464004 ! polyol transport GO:0015791 12 5 0,000 9,922E-03 0,16351237 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 9,922E-03 0,16240004 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,922E-03 0,16130274 ! response to superoxide GO:0000303 10 5 0,000 9,922E-03 0,16022017 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,922E-03 0,15915204 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 9,922E-03 0,15809805 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 9,922E-03 0,15705793 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,922E-03 0,15603141 ! female meiosis GO:0007143 7 5 0,000 9,922E-03 0,15501822 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,922E-03 0,1540181 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,922E-03 0,15303081 ! cobalt ion transport GO:0006824 11 5 0,000 9,922E-03 0,15205609 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 9,922E-03 0,15109371 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 9,922E-03 0,15014343 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 9,922E-03 0,14920504 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,922E-03 0,1482783 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,922E-03 0,147363 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 9,922E-03 0,14645893 ! embryonic camera-type eye development GO:0031076 10 5 0,000 9,922E-03 0,14556589 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,922E-03 0,14468367 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 9,922E-03 0,14381208 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 9,922E-03 0,14295093 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,922E-03 0,14210004 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,922E-03 0,14125921 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,922E-03 0,14042827 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 9,922E-03 0,13960705 ! negative chemotaxis GO:0050919 14 5 0,000 9,922E-03 0,13879538 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,922E-03 0,1379931 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,922E-03 0,13720003 ! sensory perception of bitter taste GO:0050913 7 5 0,000 9,922E-03 0,13641603 ! behavioral response to pain GO:0048266 9 5 0,000 9,922E-03 0,13564094 ! clathrin coat assembly GO:0048268 14 5 0,000 9,922E-03 0,13487461 ! Notch receptor processing GO:0007220 8 5 0,000 9,922E-03 0,13411689 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,922E-03 0,13336763 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,922E-03 0,1326267 ! micturition GO:0060073 9 5 0,000 9,922E-03 0,13189396 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,922E-03 0,13116926 ! copulation GO:0007620 9 5 0,000 9,922E-03 0,13045249 ! glial cell fate commitment GO:0021781 13 5 0,000 9,922E-03 0,12974351 ! protein maturation by protein folding GO:0022417 13 5 0,000 9,922E-03 0,12904219 ! spermidine metabolic process GO:0008216 7 5 0,000 9,922E-03 0,12834842 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,922E-03 0,12766206 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,922E-03 0,12698301 ! apoptotic cell clearance GO:0043277 20 5 0,000 9,922E-03 0,12631114 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,922E-03 0,12564635 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,922E-03 0,12498851 ! grooming behavior GO:0007625 6 5 0,000 9,922E-03 0,12433753 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,922E-03 0,1236933 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 9,922E-03 0,1230557 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,922E-03 0,12242465 ! response to protozoan GO:0001562 10 5 0,000 9,922E-03 0,12180003 ! positive regulation of glycolysis GO:0045821 14 5 0,000 9,922E-03 0,12118176 ! lymph vessel development GO:0001945 10 5 0,000 9,922E-03 0,12056973 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 9,922E-03 0,11996385 ! endochondral ossification GO:0001958 16 5 0,000 9,922E-03 0,11936403 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,922E-03 0,11877018 ! parathyroid gland development GO:0060017 13 5 0,000 9,922E-03 0,11818221 ! anagen GO:0042640 6 5 0,000 9,922E-03 0,11760003 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,922E-03 0,11702356 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,922E-03 0,11645271 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 9,922E-03 0,11588741 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 9,922E-03 0,11532757 ! dorsal spinal cord development GO:0021516 7 5 0,000 9,922E-03 0,11477311 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 9,922E-03 0,11422395 ! sphingoid catabolic process GO:0046521 6 5 0,000 9,922E-03 0,11368003 ! skeletal myofibril assembly GO:0014866 10 5 0,000 9,922E-03 0,11314126 ! smooth muscle tissue development GO:0048745 28 5 0,000 9,922E-03 0,11260758 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,922E-03 0,1120789 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,922E-03 0,11155517 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,922E-03 0,11103631 ! cardiac muscle fiber development GO:0048739 10 5 0,000 9,922E-03 0,11052225 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,922E-03 0,11001293 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 9,922E-03 0,10950828 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 9,922E-03 0,10900825 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,922E-03 0,10851275 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,922E-03 0,10802175 ! histidine catabolic process GO:0006548 6 5 0,000 9,922E-03 0,10753516 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 9,922E-03 0,10705294 ! microvillus organization GO:0032528 7 5 0,000 9,922E-03 0,10657503 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 9,922E-03 0,10610136 ! L-serine biosynthetic process GO:0006564 6 5 0,000 9,922E-03 0,10563188 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,922E-03 0,10516655 ! tryptophan metabolic process GO:0006568 9 5 0,000 9,922E-03 0,10470529 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 9,922E-03 0,10424806 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,922E-03 0,10379481 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 9,922E-03 0,10334548 ! polyol catabolic process GO:0046174 7 5 0,000 9,922E-03 0,10290003 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 9,922E-03 0,10245839 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,922E-03 0,10202054 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,922E-03 0,10158641 ! muscle cell migration GO:0014812 8 5 0,000 9,922E-03 0,10115596 ! mitochondrial fission GO:0000266 8 5 0,000 9,922E-03 0,10072914 ! sister chromatid cohesion GO:0007062 12 5 0,000 9,922E-03 0,10030591 ! mRNA transcription GO:0009299 9 5 0,000 9,922E-03 0,09988622 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 9,922E-03 0,09947002 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 9,922E-03 0,09905729 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 9,922E-03 0,09864796 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,922E-03 0,098242 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,922E-03 0,09783937 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,922E-03 0,09744002 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,922E-03 0,09704393 ! response to food GO:0032094 6 5 0,000 9,922E-03 0,09665104 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,922E-03 0,09626131 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,922E-03 0,09587472 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 9,922E-03 0,09549122 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,922E-03 0,09511078 ! paraxial mesoderm development GO:0048339 14 5 0,000 9,922E-03 0,09473336 ! forebrain neuron development GO:0021884 13 5 0,000 9,922E-03 0,09435892 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,922E-03 0,09398743 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 9,922E-03 0,09361885 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,922E-03 0,09325315 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,922E-03 0,0928903 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,922E-03 0,09253026 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 9,922E-03 0,092173 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,922E-03 0,09181848 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 9,922E-03 0,09146669 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 9,922E-03 0,09111758 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 9,922E-03 0,09077113 ! basic amino acid transport GO:0015802 11 5 0,000 9,922E-03 0,0904273 ! cellular glucose homeostasis GO:0001678 5 5 0,000 9,922E-03 0,09008606 ! early endosome to late endosome transport GO:0045022 12 5 0,000 9,922E-03 0,08974739 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,922E-03 0,08941126 ! depyrimidination GO:0045008 10 5 0,000 9,922E-03 0,08907763 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,922E-03 0,08874649 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,922E-03 0,0884178 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,922E-03 0,08809153 ! zinc ion homeostasis GO:0055069 8 5 0,000 9,922E-03 0,08776767 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 9,922E-03 0,08744618 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 9,922E-03 0,08712703 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,922E-03 0,0868102 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,922E-03 0,08649567 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,922E-03 0,08618342 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 9,922E-03 0,0858734 ! peptidyl-arginine modification GO:0018195 9 5 0,000 9,922E-03 0,08556561 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,922E-03 0,08526002 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,922E-03 0,0849566 ! response to arsenic GO:0046685 10 5 0,000 9,922E-03 0,08465534 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 9,922E-03 0,0843562 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 9,922E-03 0,08405918 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 9,922E-03 0,08376423 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 9,922E-03 0,08347135 ! response to cadmium ion GO:0046686 7 5 0,000 9,922E-03 0,08318051 ! bile acid biosynthetic process GO:0006699 6 5 0,000 9,922E-03 0,08289169 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 9,922E-03 0,08260486 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,922E-03 0,08232002 ! decidualization GO:0046697 11 5 0,000 9,922E-03 0,08203713 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 9,922E-03 0,08175618 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 9,922E-03 0,08147715 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,922E-03 0,08120002 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,922E-03 0,08092477 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 9,922E-03 0,08065137 ! base conversion or substitution editing GO:0016553 5 5 0,000 9,922E-03 0,08037982 ! neural tube patterning GO:0021532 7 5 0,000 9,922E-03 0,08011009 ! embryonic cleavage GO:0040016 6 5 0,000 9,922E-03 0,07984216 ! peroxisome fission GO:0016559 5 5 0,000 9,922E-03 0,07957602 ! histone demethylation GO:0016577 10 5 0,000 9,922E-03 0,07931165 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 9,922E-03 0,07904903 ! mitotic recombination GO:0006312 9 5 0,000 9,922E-03 0,07878814 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,922E-03 0,07852897 ! metaphase plate congression GO:0051310 7 5 0,000 9,922E-03 0,07827149 ! regulation of sterol transport GO:0032371 7 5 0,000 9,922E-03 0,07801571 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,922E-03 0,07776158 ! enteric nervous system development GO:0048484 8 5 0,000 9,922E-03 0,07750911 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 9,922E-03 0,07725827 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 9,922E-03 0,07700905 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 9,922E-03 0,07676143 ! muscle cell proliferation GO:0033002 11 5 0,000 9,922E-03 0,0765154 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,922E-03 0,07627095 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 9,922E-03 0,07602804 ! plasminogen activation GO:0031639 5 5 0,000 9,922E-03 0,07578669 ! B cell homeostasis GO:0001782 13 5 0,000 9,922E-03 0,07554685 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 9,922E-03 0,07530854 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,922E-03 0,07507172 ! metaphase GO:0051323 8 5 0,000 9,922E-03 0,07483638 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 9,922E-03 0,07460252 ! cellular response to nutrient GO:0031670 8 5 0,000 9,922E-03 0,07437011 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,922E-03 0,07413915 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,922E-03 0,07390962 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,922E-03 0,0736815 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 9,922E-03 0,07345479 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 9,922E-03 0,07322947 ! response to redox state GO:0051775 5 5 0,000 9,922E-03 0,07300552 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 9,922E-03 0,07278295 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 9,922E-03 0,07256172 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,922E-03 0,07234184 ! regulation of telomerase activity GO:0051972 6 5 0,000 9,922E-03 0,07212328 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,922E-03 0,07190604 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 9,922E-03 0,07169011 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,922E-03 0,07147547 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 9,922E-03 0,07126211 ! striatum development GO:0021756 9 5 0,000 9,922E-03 0,07105002 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 9,922E-03 0,07083919 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 9,922E-03 0,0706296 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,922E-03 0,07042126 ! glial cell migration GO:0008347 11 5 0,000 9,922E-03 0,07021414 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,922E-03 0,07000823 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 9,922E-03 0,06980353 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,922E-03 0,06960002 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,922E-03 0,06939769 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,922E-03 0,06919654 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,922E-03 0,06899655 ! neuroprotection GO:0043526 6 5 0,000 9,922E-03 0,06879771 ! neural plate development GO:0001840 8 5 0,000 9,922E-03 0,06860002 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 9,922E-03 0,06840346 ! regulation of sensory perception GO:0051931 7 5 0,000 9,922E-03 0,06820802 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,922E-03 0,06801369 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,922E-03 0,06782047 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 9,922E-03 0,06762835 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 9,922E-03 0,0674373 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,922E-03 0,06724734 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,922E-03 0,06705844 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,922E-03 0,0668706 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,922E-03 0,06668382 ! spindle assembly GO:0051225 6 5 0,000 9,922E-03 0,06649807 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 9,922E-03 0,06631335 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,922E-03 0,06612966 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,922E-03 0,06594698 ! drug metabolic process GO:0017144 6 5 0,000 9,922E-03 0,06576531 ! stem cell division GO:0017145 11 5 0,000 9,922E-03 0,06558463 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,922E-03 0,06540495 ! organ regeneration GO:0031100 7 5 0,000 9,922E-03 0,06522625 ! carnitine metabolic process GO:0009437 7 5 0,000 9,922E-03 0,06504852 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 9,922E-03 0,06487176 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,922E-03 0,06469595 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,01063559 0,0691601 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01089798 0,0706753 ! inorganic anion transport GO:0015698 138 80 1,000 0,01116321 0,07220079 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01143129 0,07373642 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01143129 0,07353926 ! response to drug GO:0042493 143 82 1,000 0,01170219 0,07508126 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01170219 0,07488158 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01189499 0,07591337 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01189499 0,07571254 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01189499 0,07551277 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01189499 0,07531405 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01189499 0,07511638 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01189499 0,07491974 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01189499 0,07472413 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01189499 0,07452953 ! sleep GO:0030431 13 6 0,000 0,01189499 0,07433595 ! response to oxygen radical GO:0000305 11 6 0,000 0,01189499 0,07414337 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01189499 0,07395178 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01189499 0,07376119 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01189499 0,07357157 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01189499 0,07338292 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01189499 0,07319524 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01189499 0,07300852 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01189499 0,07282275 ! forebrain regionalization GO:0021871 8 6 0,000 0,01189499 0,07263792 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01189499 0,07245403 ! male meiosis GO:0007140 7 6 0,000 0,01189499 0,07227106 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01189499 0,07208902 ! response to zinc ion GO:0010043 9 6 0,000 0,01189499 0,07190789 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01189499 0,07172767 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01189499 0,07154835 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01189499 0,07136993 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01189499 0,07119239 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01189499 0,07101573 ! malate metabolic process GO:0006108 11 6 0,000 0,01189499 0,07083995 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01189499 0,07066504 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01189499 0,07049099 ! protein refolding GO:0042026 15 6 0,000 0,01189499 0,07031779 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01189499 0,07014544 ! opsonization GO:0008228 8 6 0,000 0,01189499 0,06997394 ! mating behavior GO:0007617 7 6 0,000 0,01189499 0,06980327 ! neuron remodeling GO:0016322 15 6 0,000 0,01189499 0,06963343 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01189499 0,06946442 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01189499 0,06929622 ! equilibrioception GO:0050957 14 6 0,000 0,01189499 0,06912884 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01189499 0,06896226 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01189499 0,06879649 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01189499 0,06863151 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01189499 0,06846732 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01189499 0,06830391 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01189499 0,06814129 ! toxin metabolic process GO:0009404 11 6 0,000 0,01189499 0,06797943 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01189499 0,06781834 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01189499 0,06765801 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01189499 0,06749844 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01189499 0,06733962 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01189499 0,06718155 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01189499 0,06702422 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01189499 0,06686762 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01189499 0,06671175 ! thymic T cell selection GO:0045061 12 6 0,000 0,01189499 0,0665566 ! protein lipoylation GO:0009249 10 6 0,000 0,01189499 0,06640218 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01189499 0,06624847 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01189499 0,06609547 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01189499 0,06594318 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01189499 0,06579159 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01189499 0,06564069 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01189499 0,06549048 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01189499 0,06534096 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01189499 0,06519212 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01189499 0,06504395 ! hyperosmotic response GO:0006972 9 6 0,000 0,01189499 0,06489646 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01189499 0,06474964 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01189499 0,06460348 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01189499 0,06445797 ! urea metabolic process GO:0019627 7 6 0,000 0,01189499 0,06431312 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01189499 0,06416892 ! neutrophil activation GO:0042119 8 6 0,000 0,01189499 0,06402537 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01189499 0,06388246 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01189499 0,06374018 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01189499 0,06359853 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01189499 0,06345752 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01189499 0,06331712 ! neuron apoptosis GO:0051402 9 6 0,000 0,01189499 0,06317735 ! nucleoside salvage GO:0043174 9 6 0,000 0,01189499 0,06303819 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01189499 0,06289965 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01189499 0,06276171 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01189499 0,06262438 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01189499 0,06248764 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01189499 0,0623515 ! carnitine transport GO:0015879 10 6 0,000 0,01189499 0,06221596 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01189499 0,062081 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01189499 0,06194662 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01189499 0,06181283 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01189499 0,06167961 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01189499 0,06154697 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01189499 0,06141489 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01189499 0,06128338 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01189499 0,06115244 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01189499 0,06102205 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01189499 0,06089221 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01189499 0,06076293 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01189499 0,06063419 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01189499 0,060506 ! neural nucleus development GO:0048857 14 6 0,000 0,01189499 0,06037835 ! response to UV-C GO:0010225 11 6 0,000 0,01189499 0,06025124 ! astrocyte development GO:0014002 15 6 0,000 0,01189499 0,06012466 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01189499 0,05999862 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01189499 0,0598731 ! interaction with symbiont GO:0051702 13 6 0,000 0,01189499 0,0597481 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01189499 0,05962362 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01189499 0,05949967 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01189499 0,05937622 ! response to copper ion GO:0046688 10 6 0,000 0,01189499 0,05925329 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01189499 0,05913087 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01189499 0,05900895 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01189499 0,05888753 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01189499 0,05876661 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01189499 0,05864619 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01189499 0,05852626 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01189499 0,05840682 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01189499 0,05828786 ! hair follicle maturation GO:0048820 7 6 0,000 0,01189499 0,05816939 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01189499 0,0580514 ! Schwann cell development GO:0014044 15 6 0,000 0,01189499 0,05793389 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01189499 0,05781685 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01189499 0,05770028 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01189499 0,05758419 ! subpallium development GO:0021544 10 6 0,000 0,01189499 0,05746855 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01189499 0,05735339 ! histone ubiquitination GO:0016574 8 6 0,000 0,01189499 0,05723868 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01189499 0,05712443 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01189499 0,05701064 ! G2 phase GO:0051319 16 6 0,000 0,01189499 0,0568973 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01189499 0,0567844 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01189499 0,05667196 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01189499 0,05655996 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01189499 0,0564484 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01189499 0,05633728 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01189499 0,0562266 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01189499 0,05611635 ! receptor internalization GO:0031623 10 6 0,000 0,01189499 0,05600654 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01189499 0,05589715 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01189499 0,05578819 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01189499 0,05567965 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01189499 0,05557153 ! protein deubiquitination GO:0016579 14 6 0,000 0,01189499 0,05546384 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01189499 0,05535656 ! protein destabilization GO:0031648 9 6 0,000 0,01189499 0,05524969 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01189499 0,05514324 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01189499 0,05503719 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01189499 0,05493155 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01189499 0,05482632 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01189499 0,05472149 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01189499 0,05461706 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01189499 0,05451303 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01189499 0,05440939 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01189499 0,05430615 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01189499 0,0542033 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01189499 0,05410083 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01189499 0,05399875 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01189499 0,05389706 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01189499 0,05379575 ! catecholamine transport GO:0051937 9 6 0,000 0,01189499 0,05369482 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01189499 0,05359427 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01189499 0,05349409 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01189499 0,05339429 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01189499 0,05329486 ! maternal placenta development GO:0001893 12 6 0,000 0,01189499 0,0531958 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01189499 0,05309711 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01189499 0,05299878 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01189499 0,05290081 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01189499 0,05280321 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01189499 0,05270597 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01189499 0,05260908 ! response to oxygen levels GO:0070482 176 83 1,000 0,01197591 0,05286979 ! regulation of protein transport GO:0051223 154 87 1,000 0,01309869 0,05772059 GO:0070201|regulation of establishment of protein localization, ! tRNA transcription GO:0009304 14 7 0,000 0,01386391 0,06098094 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01386391 0,06086966 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01386391 0,06075879 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01386391 0,06064832 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01386391 0,06053825 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01386391 0,06042858 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01386391 0,0603193 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01386391 0,06021042 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01386391 0,06010193 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01386391 0,05999384 ! prostate gland development GO:0030850 13 7 0,000 0,01386391 0,05988613 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01386391 0,05977881 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01386391 0,05967187 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01386391 0,05956531 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01386391 0,05945913 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01386391 0,05935333 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01386391 0,05924791 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01386391 0,05914286 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01386391 0,05903818 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01386391 0,05893388 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01386391 0,05882994 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01386391 0,05872636 ! glycolipid transport GO:0046836 10 7 0,000 0,01386391 0,05862315 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01386391 0,0585203 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01386391 0,05841782 ! neuron adhesion GO:0007158 12 7 0,000 0,01386391 0,05831569 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01386391 0,05821392 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01386391 0,0581125 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01386391 0,05801143 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01386391 0,05791072 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01386391 0,05781035 ! mRNA stabilization GO:0048255 18 7 0,000 0,01386391 0,05771033 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01386391 0,05761066 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01386391 0,05751133 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01386391 0,05741235 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01386391 0,0573137 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01386391 0,05721539 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01386391 0,05711742 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01386391 0,05701978 ! lipoprotein transport GO:0042953 14 7 0,000 0,01386391 0,05692248 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01386391 0,05682551 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01386391 0,05672887 ! rhythmic behavior GO:0007622 15 7 0,000 0,01386391 0,05663255 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01386391 0,05653657 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01386391 0,0564409 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01386391 0,05634556 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01386391 0,05625055 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01386391 0,05615585 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01386391 0,05606147 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01386391 0,05596741 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01386391 0,05587366 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01386391 0,05578022 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01386391 0,0556871 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01386391 0,05559429 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01386391 0,05550179 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01386391 0,05540959 ! spinal cord patterning GO:0021511 13 7 0,000 0,01386391 0,0553177 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01386391 0,05522612 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01386391 0,05513483 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01386391 0,05504385 ! adrenal gland development GO:0030325 17 7 0,000 0,01386391 0,05495317 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01386391 0,05486279 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01386391 0,0547727 ! ovulation GO:0030728 9 7 0,000 0,01386391 0,05468291 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01386391 0,05459341 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01386391 0,05450421 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01386391 0,05441529 ! microtubule nucleation GO:0007020 20 7 0,000 0,01386391 0,05432667 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01386391 0,05423833 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01386391 0,05415028 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01386391 0,05406252 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01386391 0,05397504 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01386391 0,05388784 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01386391 0,05380093 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01386391 0,05371429 ! galactose metabolic process GO:0006012 13 7 0,000 0,01386391 0,05362793 ! response to dietary excess GO:0002021 8 7 0,000 0,01386391 0,05354185 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01386391 0,05345605 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01386391 0,05337052 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01386391 0,05328526 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01386391 0,05320028 ! organ growth GO:0035265 15 7 0,000 0,01386391 0,05311556 ! purine salvage GO:0043101 10 7 0,000 0,01386391 0,05303112 ! nucleoside transport GO:0015858 8 7 0,000 0,01386391 0,05294694 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01386391 0,05286303 ! parturition GO:0007567 14 7 0,000 0,01386391 0,05277939 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01386391 0,05269601 ! rRNA modification GO:0000154 14 7 0,000 0,01386391 0,05261289 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01386391 0,05253004 ! spindle checkpoint GO:0031577 15 7 0,000 0,01386391 0,05244744 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01386391 0,05236511 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01386391 0,05228303 ! macrophage differentiation GO:0030225 11 7 0,000 0,01386391 0,05220121 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01386391 0,05211965 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01386391 0,05203834 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01386391 0,05195728 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01386391 0,05187648 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01386391 0,05179592 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01386391 0,05171562 ! fibrinolysis GO:0042730 10 7 0,000 0,01386391 0,05163556 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01386391 0,05155576 ! eating behavior GO:0042755 7 7 0,000 0,01386391 0,05147619 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01386391 0,05139688 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01386391 0,05131781 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01386391 0,05123898 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01386391 0,05116039 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01386391 0,05108204 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01386391 0,05100394 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01386391 0,05092607 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01386391 0,05084844 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01386391 0,05077104 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01386391 0,05069388 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01386391 0,05061696 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01386391 0,05054026 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01386391 0,0504638 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01386391 0,05038757 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01386391 0,05031157 ! regulation of meiosis GO:0040020 12 7 0,000 0,01386391 0,0502358 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01386391 0,05016026 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01386391 0,05008495 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01386391 0,05000986 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01386391 0,04993499 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01386391 0,04986035 ! transcription termination GO:0006353 13 7 0,000 0,01386391 0,04978593 ! response to tumor cell GO:0002347 13 7 0,000 0,01386391 0,04971173 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01386391 0,04963776 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01386391 0,049564 ! anaphase GO:0051322 17 7 0,000 0,01386391 0,04949047 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01386391 0,04941715 ! axonal fasciculation GO:0007413 18 7 0,000 0,01386391 0,04934404 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01386391 0,04927116 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01386391 0,04919849 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01386391 0,04912603 ! diuresis GO:0030146 12 7 0,000 0,01386391 0,04905378 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01386391 0,04898175 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01386391 0,04890993 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01386391 0,04883832 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01386391 0,04876692 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01386391 0,04869573 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01386391 0,04862474 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01386391 0,04855396 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01386391 0,04848339 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01386391 0,04841302 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01386391 0,04834286 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01386391 0,0482729 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01386391 0,04820314 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01386391 0,04813358 ! lymph node development GO:0048535 10 7 0,000 0,01386391 0,04806423 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01386391 0,04799507 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01386391 0,04792611 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01386391 0,04785735 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01386391 0,04778879 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01386391 0,04772042 ! adult feeding behavior GO:0008343 9 7 0,000 0,01386391 0,04765225 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01386391 0,04758427 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01386391 0,04751649 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01386391 0,0474489 ! muscle adaptation GO:0043500 14 7 0,000 0,01386391 0,0473815 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01386391 0,04731429 ! retina homeostasis GO:0001895 12 7 0,000 0,01386391 0,04724727 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01386391 0,04718044 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01386391 0,0471138 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01386391 0,04704735 ! protein prenylation GO:0018342 18 7 0,000 0,01386391 0,04698109 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01386391 0,04691501 ! ossification GO:0001503 188 90 1,000 0,01396975 0,04720676 ! bone development GO:0060348 189 91 1,000 0,01426556 0,04813876 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,0148653 0,0500923 ! regulation of membrane potential GO:0042391 164 93 1,000 0,0148653 0,05002224 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,0148653 0,04995238 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01547578 0,05193126 ! mRNA transport GO:0051028 169 96 1,000 0,01578502 0,05289519 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01582898 0,05296874 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01582898 0,05289517 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01582898 0,05282181 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01582898 0,05274865 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01582898 0,05267569 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01582898 0,05260293 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01582898 0,05253038 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01582898 0,05245802 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01582898 0,05238587 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01582898 0,05231391 ! meiotic prophase I GO:0007128 13 8 0,000 0,01582898 0,05224215 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01582898 0,05217058 ! oligopeptide transport GO:0006857 15 8 0,000 0,01582898 0,05209921 ! UTP metabolic process GO:0046051 8 8 0,000 0,01582898 0,05202804 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01582898 0,05195706 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01582898 0,05188627 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01582898 0,05181568 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01582898 0,05174528 ! succinate metabolic process GO:0006105 14 8 0,000 0,01582898 0,05167507 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01582898 0,05160505 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01582898 0,05153522 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01582898 0,05146557 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01582898 0,05139612 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01582898 0,05132685 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01582898 0,05125777 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01582898 0,05118888 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01582898 0,05112017 ! reflex GO:0060004 16 8 0,000 0,01582898 0,05105164 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01582898 0,0509833 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01582898 0,05091514 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01582898 0,05084716 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01582898 0,05077937 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01582898 0,05071175 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01582898 0,05064431 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01582898 0,05057706 ! pigment granule organization GO:0048753 16 8 0,000 0,01582898 0,05050998 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01582898 0,05044308 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01582898 0,05037636 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01582898 0,05030981 ! histidine metabolic process GO:0006547 16 8 0,000 0,01582898 0,05024344 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01582898 0,05017724 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01582898 0,05011122 ! glycine catabolic process GO:0006546 13 8 0,000 0,01582898 0,05004537 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01582898 0,04997969 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01582898 0,04991419 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01582898 0,04984885 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01582898 0,04978369 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01582898 0,0497187 ! melanin metabolic process GO:0006582 15 8 0,000 0,01582898 0,04965388 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01582898 0,04958922 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01582898 0,04952474 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01582898 0,04946042 ! macrophage activation GO:0042116 12 8 0,000 0,01582898 0,04939627 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01582898 0,04933229 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01582898 0,04926847 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01582898 0,04920481 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01582898 0,04914132 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01582898 0,049078 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01582898 0,04901483 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01582898 0,04895183 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01582898 0,04888899 ! osteoblast development GO:0002076 16 8 0,000 0,01582898 0,04882631 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01582898 0,0487638 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01582898 0,04870144 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01582898 0,04863924 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01582898 0,0485772 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01582898 0,04851532 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01582898 0,04845359 ! response to UV-B GO:0010224 16 8 0,000 0,01582898 0,04839203 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01582898 0,04833061 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01582898 0,04826936 ! intermediate filament organization GO:0045109 12 8 0,000 0,01582898 0,04820826 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01582898 0,04814731 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01582898 0,04808652 ! cellular extravasation GO:0045123 12 8 0,000 0,01582898 0,04802588 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01582898 0,0479654 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01582898 0,04790506 ! response to antibiotic GO:0046677 11 8 0,000 0,01582898 0,04784488 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01582898 0,04778485 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01582898 0,04772497 ! DNA topological change GO:0006265 12 8 0,000 0,01582898 0,04766524 ! response to tropane GO:0014073 15 8 0,000 0,01582898 0,04760566 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01582898 0,04754622 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01582898 0,04748694 ! melanosome transport GO:0032402 13 8 0,000 0,01582898 0,0474278 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01582898 0,04736881 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01582898 0,04730997 ! mast cell activation GO:0045576 14 8 0,000 0,01582898 0,04725127 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01582898 0,04719272 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01582898 0,04713431 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01582898 0,04707605 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01582898 0,04701793 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01582898 0,04695996 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01582898 0,04690212 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01582898 0,04684443 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01582898 0,04678689 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01582898 0,04672948 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01582898 0,04667221 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01582898 0,04661509 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01582898 0,0465581 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01582898 0,04650125 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01582898 0,04644454 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01582898 0,04638797 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01582898 0,04633154 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01582898 0,04627524 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01582898 0,04621908 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01582898 0,04616306 ! hormone catabolic process GO:0042447 17 8 0,000 0,01582898 0,04610717 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01582898 0,04605142 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01582898 0,0459958 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01582898 0,04594032 ! ATP catabolic process GO:0006200 11 8 0,000 0,01582898 0,04588497 ! blastocyst growth GO:0001832 19 8 0,000 0,01582898 0,04582975 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01582898 0,04577467 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01582898 0,04571972 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01582898 0,0456649 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01582898 0,04561021 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01582898 0,04555565 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01582898 0,04550122 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01582898 0,04544693 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01582898 0,04539276 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01582898 0,04533872 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01582898 0,04528481 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01582898 0,04523103 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01582898 0,04517737 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01582898 0,04512384 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01582898 0,04507044 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01582898 0,04501717 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01582898 0,04496402 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01582898 0,044911 ! regulation of protein localization GO:0032880 176 97 1,000 0,01609691 0,04561738 ! interphase GO:0051325 213 98 1,000 0,01641144 0,04645403 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,0167286 0,04729613 GO:0060538|skeletal muscle organ development, ! regulation of developmental growth GO:0048638 15 9 0,000 0,0177902 0,05023851 ! axon extension GO:0048675 15 9 0,000 0,0177902 0,05017961 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0177902 0,05012086 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0177902 0,05006224 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0177902 0,05000375 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0177902 0,0499454 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0177902 0,04988719 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0177902 0,04982912 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0177902 0,04977118 ! phosphate transport GO:0006817 19 9 0,000 0,0177902 0,04971337 ! reproductive behavior GO:0019098 19 9 0,000 0,0177902 0,0496557 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0177902 0,04959816 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0177902 0,04954075 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0177902 0,04948348 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0177902 0,04942634 ! GTP metabolic process GO:0046039 9 9 0,000 0,0177902 0,04936933 ! RNA methylation GO:0001510 15 9 0,000 0,0177902 0,04931245 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0177902 0,04925571 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0177902 0,04919909 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0177902 0,04914261 ! artery development GO:0060840 24 9 0,000 0,0177902 0,04908625 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0177902 0,04903002 ! regulation of glycolysis GO:0006110 21 9 0,000 0,0177902 0,04897393 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0177902 0,04891796 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0177902 0,04886211 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0177902 0,0488064 ! chemosensory behavior GO:0007635 20 9 0,000 0,0177902 0,04875081 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0177902 0,04869535 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0177902 0,04864001 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0177902 0,0485848 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0177902 0,04852972 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0177902 0,04847476 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0177902 0,04841992 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0177902 0,04836521 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0177902 0,04831062 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0177902 0,04825616 ! protein targeting to ER GO:0045047 22 9 0,000 0,0177902 0,04820181 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0177902 0,04814759 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0177902 0,0480935 ! T cell selection GO:0045058 23 9 0,000 0,0177902 0,04803952 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0177902 0,04798566 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0177902 0,04793193 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0177902 0,04787831 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0177902 0,04782482 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0177902 0,04777144 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0177902 0,04771818 ! mannose metabolic process GO:0006013 13 9 0,000 0,0177902 0,04766505 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0177902 0,04761203 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0177902 0,04755912 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0177902 0,04750634 ! receptor clustering GO:0043113 18 9 0,000 0,0177902 0,04745367 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0177902 0,04740112 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0177902 0,04734868 ! ruffle organization GO:0031529 15 9 0,000 0,0177902 0,04729637 ! retinol metabolic process GO:0042572 18 9 0,000 0,0177902 0,04724416 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0177902 0,04719207 ! behavioral fear response GO:0001662 22 9 0,000 0,0177902 0,0471401 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0177902 0,04708824 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0177902 0,0470365 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0177902 0,04698486 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,0177902 0,04693335 ! protein heterooligomerization GO:0051291 16 9 0,000 0,0177902 0,04688194 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0177902 0,04683065 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0177902 0,04677947 ! segment specification GO:0007379 13 9 0,000 0,0177902 0,0467284 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0177902 0,04667744 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0177902 0,04662659 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0177902 0,04657586 ! response to amine stimulus GO:0014075 13 9 0,000 0,0177902 0,04652523 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0177902 0,04647471 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0177902 0,04642431 ! erythrocyte development GO:0048821 15 9 0,000 0,0177902 0,04637401 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0177902 0,04632382 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0177902 0,04627374 ! renal water homeostasis GO:0003091 14 9 0,000 0,0177902 0,04622377 ! postreplication repair GO:0006301 22 9 0,000 0,0177902 0,04617391 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0177902 0,04612415 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0177902 0,0460745 ! icosanoid secretion GO:0032309 15 9 0,000 0,0177902 0,04602496 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0177902 0,04597552 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0177902 0,04592619 ! regulation of cell division GO:0051302 15 9 0,000 0,0177902 0,04587697 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0177902 0,04582785 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0177902 0,04577884 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0177902 0,04572993 ! sterol catabolic process GO:0016127 11 9 0,000 0,0177902 0,04568112 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0177902 0,04563242 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0177902 0,04558382 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0177902 0,04553533 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0177902 0,04548694 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0177902 0,04543865 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0177902 0,04539047 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0177902 0,04534238 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0177902 0,0452944 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0177902 0,04524652 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0177902 0,04519874 ! purine base metabolic process GO:0006144 21 9 0,000 0,0177902 0,04515107 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0177902 0,04510349 ! pigment granule transport GO:0051904 17 9 0,000 0,0177902 0,04505601 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0177902 0,04500863 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0177902 0,04496136 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0177902 0,04491418 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0177902 0,0448671 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0177902 0,04482012 ! mitochondrion localization GO:0051646 15 9 0,000 0,0177902 0,04477323 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01974757 0,04964749 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01974757 0,04959567 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01974757 0,04954395 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01974757 0,04949234 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01974757 0,04944084 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01974757 0,04938945 ! synapsis GO:0007129 13 10 0,000 0,01974757 0,04933816 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01974757 0,04928698 ! N-glycan processing GO:0006491 20 10 0,000 0,01974757 0,04923591 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01974757 0,04918494 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01974757 0,04913408 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01974757 0,04908332 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01974757 0,04903266 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01974757 0,04898211 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01974757 0,04893167 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01974757 0,04888133 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01974757 0,04883109 ! androgen metabolic process GO:0008209 17 10 0,000 0,01974757 0,04878096 ! phospholipid efflux GO:0033700 16 10 0,000 0,01974757 0,04873092 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01974757 0,04868099 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01974757 0,04863117 ! lung alveolus development GO:0048286 26 10 0,000 0,01974757 0,04858144 ! pathogenesis GO:0009405 13 10 0,000 0,01974757 0,04853182 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01974757 0,0484823 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01974757 0,04843288 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01974757 0,04838355 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01974757 0,04833433 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01974757 0,04828521 ! endoderm development GO:0007492 16 10 0,000 0,01974757 0,04823619 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01974757 0,04818727 ! arginine catabolic process GO:0006527 13 10 0,000 0,01974757 0,04813845 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01974757 0,04808973 ! proline metabolic process GO:0006560 13 10 0,000 0,01974757 0,0480411 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01974757 0,04799258 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01974757 0,04794415 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01974757 0,04789582 ! V(D)J recombination GO:0033151 28 10 0,000 0,01974757 0,04784758 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01974757 0,04779945 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01974757 0,04775141 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01974757 0,04770346 ! B cell proliferation GO:0042100 18 10 0,000 0,01974757 0,04765562 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01974757 0,04760787 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01974757 0,04756021 ! multicellular organism growth GO:0035264 18 10 0,000 0,01974757 0,04751265 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01974757 0,04746519 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01974757 0,04741781 ! epithelial cell development GO:0002064 20 10 0,000 0,01974757 0,04737054 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01974757 0,04732336 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01974757 0,04727627 ! macroautophagy GO:0016236 17 10 0,000 0,01974757 0,04722927 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01974757 0,04718237 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01974757 0,04713557 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01974757 0,04708885 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01974757 0,04704223 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01974757 0,0469957 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01974757 0,04694926 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01974757 0,04690291 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01974757 0,04685666 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01974757 0,04681049 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01974757 0,04676442 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01974757 0,04671844 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01974757 0,04667254 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01974757 0,04662674 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01974757 0,04658103 ! response to dsRNA GO:0043331 20 10 0,000 0,01974757 0,04653541 ! DNA ligation GO:0006266 19 10 0,000 0,01974757 0,04648987 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01974757 0,04644443 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01974757 0,04639907 ! melanosome localization GO:0032400 16 10 0,000 0,01974757 0,04635381 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01974757 0,04630863 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01974757 0,04626354 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01974757 0,04621853 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01974757 0,04617362 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01974757 0,04612879 ! mRNA cleavage GO:0006379 17 10 0,000 0,01974757 0,04608405 ! protein sumoylation GO:0016925 15 10 0,000 0,01974757 0,04603939 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01974757 0,04599482 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01974757 0,04595034 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01974757 0,04590594 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01974757 0,04586163 ! salivary gland development GO:0007431 27 10 0,000 0,01974757 0,04581741 ! prophase GO:0051324 15 10 0,000 0,01974757 0,04577327 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01974757 0,04572921 ! apical protein localization GO:0045176 15 10 0,000 0,01974757 0,04568524 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01974757 0,04564135 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01974757 0,04559755 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01974757 0,04555384 ! midbrain development GO:0030901 13 10 0,000 0,01974757 0,0455102 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01974757 0,04546665 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01974757 0,04542318 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01974757 0,0453798 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01974757 0,0453365 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01974757 0,04529328 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01974757 0,04525014 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01974757 0,04520709 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01974757 0,04516412 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01974757 0,04512123 ! oocyte development GO:0048599 17 10 0,000 0,01974757 0,04507842 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01974757 0,04503569 ! blastocyst formation GO:0001825 17 10 0,000 0,01974757 0,04499304 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01974757 0,04495047 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01974757 0,04490799 ! activation of innate immune response GO:0002218 12 10 0,000 0,01974757 0,04486558 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01974757 0,04482326 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01974757 0,04478101 ! response to nicotine GO:0035094 20 10 0,000 0,01974757 0,04473884 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01974757 0,04469675 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01974757 0,04465475 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01974757 0,04461282 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02170111 0,04898017 ! respiratory burst GO:0045730 17 11 0,000 0,02170111 0,04893427 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02170111 0,04888845 ! neuron fate specification GO:0048665 17 11 0,000 0,02170111 0,04884271 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02170111 0,04879707 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02170111 0,0487515 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02170111 0,04870603 ! thyroid gland development GO:0030878 26 11 0,000 0,02170111 0,04866063 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02170111 0,04861533 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02170111 0,0485701 ! response to pain GO:0048265 24 11 0,000 0,02170111 0,04852496 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02170111 0,04847991 ! T cell proliferation GO:0042098 26 11 0,000 0,02170111 0,04843494 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02170111 0,04839005 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02170111 0,04834524 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02170111 0,04830052 ! bone resorption GO:0045453 16 11 0,000 0,02170111 0,04825588 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02170111 0,04821132 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02170111 0,04816685 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02170111 0,04812245 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02170111 0,04807814 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02170111 0,04803391 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02170111 0,04798976 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02170111 0,04794569 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02170111 0,04790171 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02170111 0,0478578 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02170111 0,04781398 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02170111 0,04777023 ! lipid digestion GO:0044241 18 11 0,000 0,02170111 0,04772656 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02170111 0,04768298 ! UV protection GO:0009650 19 11 0,000 0,02170111 0,04763947 ! adult heart development GO:0007512 14 11 0,000 0,02170111 0,04759604 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02170111 0,0475527 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02170111 0,04750943 ! temperature homeostasis GO:0001659 17 11 0,000 0,02170111 0,04746624 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02170111 0,04742313 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02170111 0,04738009 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02170111 0,04733714 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02170111 0,04729426 ! regulation of organ growth GO:0046620 13 11 0,000 0,02170111 0,04725146 ! pigment granule localization GO:0051875 20 11 0,000 0,02170111 0,04720874 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02170111 0,04716609 ! vasoconstriction GO:0042310 18 11 0,000 0,02170111 0,04712352 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02170111 0,04708103 ! embryonic axis specification GO:0000578 18 11 0,000 0,02170111 0,04703861 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02170111 0,04699627 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02170111 0,04695401 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02170111 0,04691182 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02170111 0,04686971 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02170111 0,04682768 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02170111 0,04678572 ! zymogen activation GO:0031638 15 11 0,000 0,02170111 0,04674383 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02170111 0,04670202 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02170111 0,04666029 ! nucleosome positioning GO:0016584 15 11 0,000 0,02170111 0,04661863 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02170111 0,04657704 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02170111 0,04653553 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02170111 0,04649409 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02170111 0,04645272 ! acid secretion GO:0046717 18 11 0,000 0,02170111 0,04641143 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02170111 0,04637021 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02170111 0,04632907 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02170111 0,046288 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02170111 0,046247 ! oocyte differentiation GO:0009994 18 11 0,000 0,02170111 0,04620607 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02170111 0,04616522 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02170111 0,04612444 ! cholesterol efflux GO:0033344 19 11 0,000 0,02170111 0,04608373 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02170111 0,04604309 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02170111 0,04600252 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02170111 0,04596203 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02170111 0,0459216 ! embryonic gut development GO:0048566 15 11 0,000 0,02170111 0,04588125 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02170111 0,04584097 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02170111 0,04580076 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02170111 0,04576061 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02170111 0,04572054 ! defense response to fungus GO:0050832 13 11 0,000 0,02170111 0,04568054 ! lysogeny GO:0030069 21 11 0,000 0,02170111 0,04564061 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02170111 0,04560075 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02170111 0,04556096 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02170111 0,04552124 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02170111 0,04548159 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02170111 0,045442 ! nucleus localization GO:0051647 19 11 0,000 0,02170111 0,04540249 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02170111 0,04536304 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02365081 0,04939571 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02365081 0,04935287 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02365081 0,0493101 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02365081 0,04926741 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02365081 0,04922479 ! virus-host interaction GO:0019048 29 12 0,000 0,02365081 0,04918225 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02365081 0,04913978 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02365081 0,04909738 ! cartilage condensation GO:0001502 20 12 0,000 0,02365081 0,04905505 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02365081 0,0490128 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02365081 0,04897062 ! protein complex disassembly GO:0043241 27 12 0,000 0,02365081 0,04892851 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02365081 0,04888648 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02365081 0,04884452 ! hippocampus development GO:0021766 26 12 0,000 0,02365081 0,04880262 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02365081 0,04876081 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02365081 0,04871906 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02365081 0,04867738 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02365081 0,04863578 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02365081 0,04859424 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02365081 0,04855278 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02365081 0,04851139 ! drug transport GO:0015893 16 12 0,000 0,02365081 0,04847007 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02365081 0,04842882 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02365081 0,04838764 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02365081 0,04834653 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02365081 0,04830548 ! focal adhesion formation GO:0048041 35 12 0,000 0,02365081 0,04826451 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02365081 0,04822361 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02365081 0,04818278 ! forebrain cell migration GO:0021885 21 12 0,000 0,02365081 0,04814201 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02365081 0,04810132 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02365081 0,04806069 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02365081 0,04802014 ! entry into host cell GO:0030260 32 12 0,000 0,02365081 0,04797965 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02365081 0,04793923 ! monoamine transport GO:0015844 18 12 0,000 0,02365081 0,04789887 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02365081 0,04785859 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02365081 0,04781837 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02365081 0,04777822 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02365081 0,04773814 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02365081 0,04769812 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02365081 0,04765817 ! protein homotetramerization GO:0051289 21 12 0,000 0,02365081 0,04761829 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02365081 0,04757848 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02365081 0,04753873 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02365081 0,04749905 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02365081 0,04745943 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02365081 0,04741988 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02365081 0,0473804 ! cranial nerve development GO:0021545 20 12 0,000 0,02365081 0,04734098 ! fucose catabolic process GO:0019317 22 12 0,000 0,02365081 0,04730163 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02365081 0,04726234 ! histone acetylation GO:0016573 26 12 0,000 0,02365081 0,04722312 ! histone methylation GO:0016571 26 12 0,000 0,02365081 0,04718396 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02365081 0,04714487 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02365081 0,04710584 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02365081 0,04706688 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02365081 0,04702798 ! T cell homeostasis GO:0043029 25 12 0,000 0,02365081 0,04698915 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02365081 0,04695038 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02365081 0,04691167 ! spleen development GO:0048536 22 12 0,000 0,02365081 0,04687303 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02365081 0,04683445 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02365081 0,04679594 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02365081 0,04675749 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02365081 0,0467191 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02365081 0,04668077 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02365081 0,04664251 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02365081 0,04660431 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02365081 0,04656617 ! response to cold GO:0009409 17 12 0,000 0,02365081 0,0465281 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02365081 0,04649008 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02365081 0,04645213 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0255967 0,05023301 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0255967 0,05019207 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0255967 0,05015119 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0255967 0,05011039 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,0255967 0,05006965 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0255967 0,05002897 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,0255967 0,04998837 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0255967 0,04994782 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0255967 0,04990735 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0255967 0,04986694 ! endocrine pancreas development GO:0031018 22 13 0,000 0,0255967 0,04982659 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0255967 0,04978631 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0255967 0,0497461 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0255967 0,04970595 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0255967 0,04966586 ! methionine metabolic process GO:0006555 27 13 0,000 0,0255967 0,04962584 ! plasma membrane organization GO:0007009 24 13 0,000 0,0255967 0,04958588 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0255967 0,04954599 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0255967 0,04950616 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0255967 0,0494664 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,0255967 0,0494267 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0255967 0,04938706 ! response to X-ray GO:0010165 25 13 0,000 0,0255967 0,04934749 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0255967 0,04930798 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,0255967 0,04926853 ! exocrine system development GO:0035272 32 13 0,000 0,0255967 0,04922915 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,0255967 0,04918983 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0255967 0,04915057 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0255967 0,04911138 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0255967 0,04907224 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0255967 0,04903317 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0255967 0,04899417 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0255967 0,04895522 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0255967 0,04891634 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0255967 0,04887751 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0255967 0,04883875 ! regulation of cellular pH GO:0030641 22 13 0,000 0,0255967 0,04880005 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0255967 0,04876141 ! ribosome assembly GO:0042255 17 13 0,000 0,0255967 0,04872284 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0255967 0,04868432 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0255967 0,04864587 ! chromatin silencing GO:0006342 26 13 0,000 0,0255967 0,04860747 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0255967 0,04856914 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0255967 0,04853086 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0255967 0,04849265 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0255967 0,0484545 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0255967 0,0484164 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,0255967 0,04837837 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0255967 0,0483404 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0255967 0,04830248 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0255967 0,04826463 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0255967 0,04822683 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0255967 0,0481891 ! embryonic placenta development GO:0001892 23 13 0,000 0,0255967 0,04815142 ! insulin secretion GO:0030073 23 13 0,000 0,0255967 0,0481138 ! actin filament polymerization GO:0030041 24 13 0,000 0,0255967 0,04807624 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,0255967 0,04803874 ! acrosome reaction GO:0007340 18 13 0,000 0,0255967 0,0480013 ! rRNA transcription GO:0009303 25 14 0,000 0,02753878 0,05160303 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02753878 0,05156288 ! reproductive cellular process GO:0048610 20 14 0,000 0,02753878 0,05152278 ! tRNA modification GO:0006400 20 14 0,000 0,02753878 0,05148275 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02753878 0,05144278 ! regulation of S phase GO:0033261 23 14 0,000 0,02753878 0,05140287 ! water transport GO:0006833 21 14 0,000 0,02753878 0,05136302 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02753878 0,05132324 ! non-recombinational repair GO:0000726 25 14 0,000 0,02753878 0,05128351 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02753878 0,05124385 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02753878 0,05120425 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02753878 0,05116471 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02753878 0,05112523 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02753878 0,05108581 ! palate development GO:0060021 31 14 0,000 0,02753878 0,05104645 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02753878 0,05100716 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02753878 0,05096792 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02753878 0,05092874 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02753878 0,05088963 ! arginine metabolic process GO:0006525 17 14 0,000 0,02753878 0,05085057 ! regulation of heart rate GO:0002027 24 14 0,000 0,02753878 0,05081158 ! organic alcohol transport GO:0015850 29 14 0,000 0,02753878 0,05077264 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02753878 0,05073376 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02753878 0,05069495 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02753878 0,05065619 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02753878 0,05061749 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02753878 0,05057885 ! L-amino acid transport GO:0015807 30 14 0,000 0,02753878 0,05054027 ! bone mineralization GO:0030282 17 14 0,000 0,02753878 0,05050175 ! stem cell development GO:0048864 43 14 0,000 0,02753878 0,05046329 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02753878 0,05042488 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02753878 0,05038654 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02753878 0,05034825 ! cerebellum development GO:0021549 21 14 0,000 0,02753878 0,05031002 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02753878 0,05027185 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02753878 0,05023374 ! response to gamma radiation GO:0010332 28 14 0,000 0,02753878 0,05019568 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02753878 0,05015768 ! cofactor transport GO:0051181 26 14 0,000 0,02753878 0,05011974 ! NADP metabolic process GO:0006739 24 14 0,000 0,02753878 0,05008186 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02753878 0,05004403 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02753878 0,05000626 ! intestinal absorption GO:0050892 25 14 0,000 0,02753878 0,04996855 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02753878 0,04993089 ! oxygen transport GO:0015671 21 14 0,000 0,02753878 0,0498933 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02753878 0,04985575 ! male genitalia development GO:0030539 24 14 0,000 0,02753878 0,04981827 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02753878 0,04978084 ! regulation of axon extension GO:0030516 37 14 0,000 0,02753878 0,04974347 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02753878 0,04970615 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02753878 0,04966889 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02947704 0,05312492 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02947704 0,05308516 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02947704 0,05304545 ! superoxide anion generation GO:0042554 20 15 0,000 0,02947704 0,05300581 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02947704 0,05296622 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02947704 0,05292669 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02947704 0,05288723 ! copper ion transport GO:0006825 20 15 0,000 0,02947704 0,05284782 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02947704 0,05280847 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02947704 0,05276917 ! sulfate transport GO:0008272 23 15 0,000 0,02947704 0,05272994 ! response to cAMP GO:0051591 22 15 0,000 0,02947704 0,05269076 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02947704 0,05265165 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02947704 0,05261259 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02947704 0,05257359 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02947704 0,05253464 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02947704 0,05249576 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02947704 0,05245693 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02947704 0,05241816 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02947704 0,05237945 ! pituitary gland development GO:0021983 29 15 0,000 0,02947704 0,05234079 ! vesicle coating GO:0006901 33 15 0,000 0,02947704 0,05230219 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02947704 0,05226365 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02947704 0,05222516 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02947704 0,05218673 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02947704 0,05214836 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02947704 0,05211004 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02947704 0,05207178 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02947704 0,05203358 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02947704 0,05199543 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02947704 0,05195734 ! histone deacetylation GO:0016575 20 15 0,000 0,02947704 0,0519193 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02947704 0,05188132 ! tissue regeneration GO:0042246 26 15 0,000 0,02947704 0,0518434 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02947704 0,05180553 ! water homeostasis GO:0030104 27 15 0,000 0,02947704 0,05176771 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02947704 0,05172996 ! muscle maintenance GO:0046716 26 15 0,000 0,02947704 0,05169225 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02947704 0,0516546 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02947704 0,05161701 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02947704 0,05157947 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02947704 0,05154198 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02947704 0,05150455 ! cell killing GO:0001906 29 15 0,000 0,02947704 0,05146718 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02947704 0,05142985 ! detection of bacterium GO:0016045 18 15 0,000 0,02947704 0,05139259 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02947704 0,05135537 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02947704 0,05131821 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02947704 0,05128111 ! peptide hormone processing GO:0016486 23 15 0,000 0,02947704 0,05124405 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03141151 0,05456758 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03141151 0,05452821 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03141151 0,0544889 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03141151 0,05444964 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03141151 0,05441044 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03141151 0,0543713 ! bone remodeling GO:0046849 27 16 0,000 0,03141151 0,05433221 ! filopodium assembly GO:0046847 32 16 0,000 0,03141151 0,05429318 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03141151 0,0542542 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03141151 0,05421528 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03141151 0,05417642 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03141151 0,05413761 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03141151 0,05409886 ! startle response GO:0001964 28 16 0,000 0,03141151 0,05406016 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03141151 0,05402152 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03141151 0,05398293 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03141151 0,0539444 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03141151 0,05390592 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03141151 0,0538675 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03141151 0,05382913 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03141151 0,05379082 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03141151 0,05375256 ! response to osmotic stress GO:0006970 25 16 0,000 0,03141151 0,05371436 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03141151 0,05367621 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03141151 0,05363811 ! fructose metabolic process GO:0006000 25 16 0,000 0,03141151 0,05360007 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03141151 0,05356208 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03141151 0,05352415 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03141151 0,05348627 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03141151 0,05344844 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03141151 0,05341067 ! axon cargo transport GO:0008088 43 16 0,000 0,03141151 0,05337295 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03141151 0,05333529 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03141151 0,05329767 ! DNA replication initiation GO:0006270 27 16 0,000 0,03141151 0,05326011 ! neuron recognition GO:0008038 35 16 0,000 0,03141151 0,05322261 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03141151 0,05318515 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03141151 0,05314775 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03141151 0,0531104 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03141151 0,0530731 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03141151 0,05303586 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03141151 0,05299867 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03141151 0,05296153 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03141151 0,05292444 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03141151 0,0528874 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03141151 0,05285042 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03141151 0,05281349 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03141151 0,05277661 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03141151 0,05273978 ! defense response to virus GO:0051607 37 16 0,000 0,03141151 0,052703 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03334219 0,05590335 ! metencephalon development GO:0022037 30 17 0,000 0,03334219 0,05586442 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03334219 0,05582555 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03334219 0,05578672 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03334219 0,05574796 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03334219 0,05570924 ! signal complex assembly GO:0007172 41 17 0,000 0,03334219 0,05567058 ! endothelial cell migration GO:0043542 28 17 0,000 0,03334219 0,05563198 ! inositol metabolic process GO:0006020 28 17 0,000 0,03334219 0,05559342 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03334219 0,05555492 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03334219 0,05551648 ! glial cell development GO:0021782 27 17 0,000 0,03334219 0,05547808 ! limbic system development GO:0021761 36 17 0,000 0,03334219 0,05543974 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03334219 0,05540146 ! adult walking behavior GO:0007628 33 17 0,000 0,03334219 0,05536322 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03334219 0,05532504 ! heart looping GO:0001947 30 17 0,000 0,03334219 0,05528691 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03334219 0,05524884 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03334219 0,05521081 ! myoblast differentiation GO:0045445 45 17 0,000 0,03334219 0,05517284 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03334219 0,05513492 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03334219 0,05509705 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03334219 0,05505924 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03334219 0,05502147 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03334219 0,05498376 ! glycine metabolic process GO:0006544 28 17 0,000 0,03334219 0,0549461 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03334219 0,05490849 ! NAD metabolic process GO:0019674 29 17 0,000 0,03334219 0,05487094 ! membrane budding GO:0006900 37 17 0,000 0,03334219 0,05483343 ! DNA integration GO:0015074 29 17 0,000 0,03334219 0,05479598 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03334219 0,05475857 ! regulation of protein binding GO:0043393 33 17 0,000 0,03334219 0,05472122 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03334219 0,05468392 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03334219 0,05464667 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03334219 0,05460947 ! genitalia development GO:0048806 30 17 0,000 0,03334219 0,05457232 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03334219 0,05453522 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03334219 0,05449817 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03334219 0,05446117 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03334219 0,05442423 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03334219 0,05438733 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03334219 0,05435048 ! steroid catabolic process GO:0006706 31 17 0,000 0,03334219 0,05431368 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03334219 0,05427693 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03334219 0,05424024 ! gas transport GO:0015669 25 17 0,000 0,03334219 0,05420359 ! organic cation transport GO:0015695 31 17 0,000 0,03334219 0,05416699 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03334219 0,05413044 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03334219 0,05409394 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03334219 0,05405749 ! microspike assembly GO:0030035 36 17 0,000 0,03334219 0,05402108 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03334219 0,05398473 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03334219 0,05394843 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03526908 0,05702783 ! neuron maturation GO:0042551 42 18 0,000 0,03526908 0,05698953 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03526908 0,05695128 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03526908 0,05691309 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03526908 0,05687494 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03526908 0,05683685 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03526908 0,0567988 ! memory GO:0007613 31 18 0,000 0,03526908 0,05676081 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03526908 0,05672287 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03526908 0,05668498 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03526908 0,05664714 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03526908 0,05660935 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03526908 0,05657161 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03526908 0,05653392 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03526908 0,05649628 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03526908 0,05645869 ! response to retinoic acid GO:0032526 26 18 0,000 0,03526908 0,05642115 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03526908 0,05638366 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03526908 0,05634622 ! response to fungus GO:0009620 21 18 0,000 0,03526908 0,05630883 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03526908 0,05627149 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03526908 0,0562342 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03526908 0,05619696 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03526908 0,05615977 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03526908 0,05612263 ! vitamin transport GO:0051180 27 18 0,000 0,03526908 0,05608553 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03526908 0,05604849 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03526908 0,05601149 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03526908 0,05597455 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03526908 0,05593765 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03526908 0,0559008 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03526908 0,055864 ! nerve development GO:0021675 28 18 0,000 0,03526908 0,05582725 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03526908 0,05579054 ! protein secretion GO:0009306 39 19 0,000 0,0371922 0,05879397 ! positive regulation of translation GO:0045727 30 19 0,000 0,0371922 0,05875537 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0371922 0,05871682 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0371922 0,05867831 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0371922 0,05863986 ! skin development GO:0043588 36 19 0,000 0,0371922 0,05860146 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0371922 0,05856311 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0371922 0,05852481 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0371922 0,05848656 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0371922 0,05844835 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0371922 0,0584102 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0371922 0,0583721 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0371922 0,05833405 ! cerebral cortex development GO:0021987 36 19 0,000 0,0371922 0,05829605 ! pigmentation during development GO:0048066 41 19 0,000 0,0371922 0,05825809 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0371922 0,05822019 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,0371922 0,05818233 ! heme metabolic process GO:0042168 36 19 0,000 0,0371922 0,05814453 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0371922 0,05810677 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0371922 0,05806907 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0371922 0,05803141 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0371922 0,0579938 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0371922 0,05795624 ! peptide cross-linking GO:0018149 37 19 0,000 0,0371922 0,05791872 ! protein export from nucleus GO:0006611 36 19 0,000 0,0371922 0,05788126 ! heart process GO:0003015 30 19 0,000 0,0371922 0,05784385 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0371922 0,05780648 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0371922 0,05776916 ! visual learning GO:0008542 36 19 0,000 0,0371922 0,05773189 ! cellular pigmentation GO:0033059 36 19 0,000 0,0371922 0,05769467 ! G1 phase GO:0051318 40 19 0,000 0,0371922 0,05765749 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0371922 0,05762037 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0371922 0,05758329 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0371922 0,05754626 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0371922 0,05750927 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0371922 0,05747234 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0371922 0,05743545 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0371922 0,05739861 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0371922 0,05736181 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0371922 0,05732507 ! cilium assembly GO:0042384 37 19 0,000 0,0371922 0,05728837 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0371922 0,05725171 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03911154 0,06016776 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03911154 0,06012931 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03911154 0,06009092 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03911154 0,06005257 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03911154 0,06001427 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03911154 0,05997602 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03911154 0,05993782 ! response to vitamin GO:0033273 31 20 0,000 0,03911154 0,05989967 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03911154 0,05986156 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03911154 0,05982351 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03911154 0,0597855 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03911154 0,05974754 ! response to alkaloid GO:0043279 38 20 0,000 0,03911154 0,05970963 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03911154 0,05967177 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03911154 0,05963395 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03911154 0,05959618 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03911154 0,05955847 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03911154 0,05952079 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03911154 0,05948317 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03911154 0,05944559 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03911154 0,05940807 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03911154 0,05937058 ! body fluid secretion GO:0007589 31 20 0,000 0,03911154 0,05933315 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03911154 0,05929576 ! peptide secretion GO:0002790 35 20 0,000 0,03911154 0,05925842 ! stem cell differentiation GO:0048863 53 20 0,000 0,03911154 0,05922113 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03911154 0,05918388 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03911154 0,05914668 ! sensory perception of pain GO:0019233 30 20 0,000 0,03911154 0,05910953 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03911154 0,05907243 ! diencephalon development GO:0021536 34 20 0,000 0,03911154 0,05903537 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03911154 0,05899835 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03911154 0,05896139 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03911154 0,05892447 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03911154 0,05888759 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03911154 0,05885077 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03911154 0,05881398 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03911154 0,05877725 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03911154 0,05874056 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03911154 0,05870391 ! regulation of glucose import GO:0046324 29 20 0,000 0,03911154 0,05866732 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03911154 0,05863076 ! actin filament-based movement GO:0030048 43 20 0,000 0,03911154 0,05859426 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03911154 0,05855779 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03911154 0,05852138 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03911154 0,05848501 ! negative regulation of translation GO:0017148 29 20 0,000 0,03911154 0,05844868 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03911154 0,0584124 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03911154 0,05837616 ! regulation of cell killing GO:0031341 42 21 0,000 0,04102713 0,06119731 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04102713 0,0611594 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04102713 0,06112153 ! hormone secretion GO:0046879 38 21 0,000 0,04102713 0,06108371 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04102713 0,06104593 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04102713 0,0610082 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04102713 0,06097052 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04102713 0,06093288 ! axis specification GO:0009798 38 21 0,000 0,04102713 0,06089529 ! ovarian follicle development GO:0001541 35 21 0,000 0,04102713 0,06085775 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04102713 0,06082025 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04102713 0,0607828 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04102713 0,0607454 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04102713 0,06070804 ! cell aging GO:0007569 44 21 0,000 0,04102713 0,06067072 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04102713 0,06063346 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04102713 0,06059624 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04102713 0,06055906 ! cytolysis GO:0019835 24 21 0,000 0,04102713 0,06052193 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04102713 0,06048485 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04102713 0,06044781 ! oogenesis GO:0048477 36 21 0,000 0,04102713 0,06041081 ! DNA modification GO:0006304 34 21 0,000 0,04102713 0,06037386 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04102713 0,06033696 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04102713 0,0603001 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04102713 0,06026329 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04102713 0,06022652 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04102713 0,0601898 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04102713 0,06015312 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04102713 0,06011648 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04102713 0,0600799 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04102713 0,06004335 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04102713 0,06000685 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04102713 0,05997039 ! collagen catabolic process GO:0030574 28 21 0,000 0,04102713 0,05993398 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04102713 0,05989761 ! gut development GO:0048565 39 21 0,000 0,04102713 0,05986129 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04293896 0,0626128 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04293896 0,06257488 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04293896 0,062537 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04293896 0,06249917 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04293896 0,06246138 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04293896 0,06242364 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04293896 0,06238595 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04293896 0,0623483 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04293896 0,06231069 ! regeneration GO:0031099 41 22 0,000 0,04293896 0,06227313 ! keratinization GO:0031424 28 22 0,000 0,04293896 0,06223562 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04293896 0,06219815 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04293896 0,06216073 ! sensory perception of taste GO:0050909 28 22 0,000 0,04293896 0,06212335 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04293896 0,06208601 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04293896 0,06204872 ! vacuolar transport GO:0007034 36 22 0,000 0,04293896 0,06201148 ! lysosome organization GO:0007040 41 22 0,000 0,04293896 0,06197428 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04293896 0,06193713 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04293896 0,06190002 ! fucose metabolic process GO:0006004 39 22 0,000 0,04293896 0,06186295 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04293896 0,06182593 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04293896 0,06178895 ! ureteric bud development GO:0001657 43 22 0,000 0,04293896 0,06175202 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04293896 0,06171513 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04293896 0,06167828 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04293896 0,06164148 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04293896 0,06160473 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04293896 0,06156801 ! sarcomere organization GO:0045214 30 22 0,000 0,04293896 0,06153134 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04293896 0,06149472 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04293896 0,06145814 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04293896 0,0614216 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04293896 0,0613851 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04293896 0,06134865 ! protein stabilization GO:0050821 39 22 0,000 0,04293896 0,06131224 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,04484704 0,06399879 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04484704 0,06396086 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04484704 0,06392297 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04484704 0,06388512 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04484704 0,06384732 ! gluconeogenesis GO:0006094 33 23 0,000 0,04484704 0,06380956 ! viral genome replication GO:0019079 41 23 0,000 0,04484704 0,06377185 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04484704 0,06373418 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04484704 0,06369656 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04484704 0,06365898 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04484704 0,06362144 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04484704 0,06358395 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04484704 0,06354651 ! visual behavior GO:0007632 42 23 0,000 0,04484704 0,0635091 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04484704 0,06347174 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04484704 0,06343443 ! response to ethanol GO:0045471 46 23 0,000 0,04484704 0,06339716 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04484704 0,06335993 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04484704 0,06332275 ! peroxisome organization GO:0007031 37 23 0,000 0,04484704 0,06328561 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04484704 0,06324851 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04484704 0,06321146 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04484704 0,06317445 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04484704 0,06313749 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,04484704 0,06310057 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04484704 0,06306369 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04484704 0,06302685 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04484704 0,06299006 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04484704 0,06295331 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04484704 0,0629166 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04484704 0,06287993 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04484704 0,06284331 ! fatty acid transport GO:0015908 44 23 0,000 0,04484704 0,06280673 ! platelet activation GO:0030168 37 23 0,000 0,04484704 0,0627702 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04484704 0,0627337 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04484704 0,06269725 ! hormone transport GO:0009914 40 23 0,000 0,04484704 0,06266084 ! cell-cell recognition GO:0009988 25 23 0,000 0,04484704 0,06262447 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04484704 0,06258815 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04484704 0,06255186 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04484704 0,06251562 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04484704 0,06247942 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04484704 0,06244327 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04675137 0,06505715 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,04675137 0,06501954 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04675137 0,06498198 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,04675137 0,06494446 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04675137 0,06490699 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04675137 0,06486955 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04675137 0,06483216 ! spinal cord development GO:0021510 47 24 0,000 0,04675137 0,06479482 ! vacuole organization GO:0007033 43 24 0,000 0,04675137 0,06475752 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04675137 0,06472026 ! digestive system process GO:0022600 39 24 0,000 0,04675137 0,06468304 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04675137 0,06464587 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04675137 0,06460873 ! regulation of behavior GO:0050795 43 24 0,000 0,04675137 0,06457165 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04675137 0,0645346 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04675137 0,0644976 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04675137 0,06446063 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,04675137 0,06442371 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04675137 0,06438684 ! pallium development GO:0021543 49 24 0,000 0,04675137 0,06435 ! pentose metabolic process GO:0019321 35 24 0,000 0,04675137 0,06431321 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04675137 0,06427646 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04675137 0,06423975 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04675137 0,06420309 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04675137 0,06416646 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04675137 0,06412988 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04675137 0,06409334 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04675137 0,06405684 ! regulation of amine transport GO:0051952 40 24 0,000 0,04675137 0,06402038 ! protein tetramerization GO:0051262 52 24 0,000 0,04675137 0,06398396 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,04865198 0,06654728 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,04865198 0,06650947 ! myelination GO:0042552 45 25 0,000 0,04865198 0,0664717 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,04865198 0,06643397 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,04865198 0,06639629 ! phototransduction GO:0007602 33 25 0,000 0,04865198 0,06635865 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,04865198 0,06632106 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,04865198 0,0662835 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,04865198 0,06624599 ! receptor metabolic process GO:0043112 46 25 0,000 0,04865198 0,06620852 ! chromosome condensation GO:0030261 45 25 0,000 0,04865198 0,06617109 ! response to starvation GO:0042594 42 25 0,000 0,04865198 0,06613371 ! osteoblast differentiation GO:0001649 60 25 0,000 0,04865198 0,06609637 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,04865198 0,06605906 ! neural crest cell development GO:0014032 54 25 0,000 0,04865198 0,06602181 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,04865198 0,06598459 ! negative regulation of cell development GO:0010721 73 25 0,000 0,04865198 0,06594742 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,04865198 0,06591028 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,04865198 0,06587319 ! interaction with host GO:0051701 62 25 0,000 0,04865198 0,06583614 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,04865198 0,06579914 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,04865198 0,06576217 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,04865198 0,06572525 ! immunoglobulin production GO:0002377 55 25 0,000 0,04865198 0,06568836 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,04865198 0,06565152 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,04865198 0,06561472 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,04865198 0,06557796 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,04865198 0,06554124 ! telomere organization GO:0032200 43 25 0,000 0,04865198 0,06550457 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,04865198 0,06546793 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,04865198 0,06543134 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05054886 0,06794444 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05054886 0,06790651 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05054886 0,06786861 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05054886 0,06783076 ! initiation of viral infection GO:0019059 57 26 0,000 0,05054886 0,06779295 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05054886 0,06775518 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05054886 0,06771746 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05054886 0,06767977 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05054886 0,06764213 ! molting cycle process GO:0022404 50 26 0,000 0,05054886 0,06760453 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05054886 0,06756697 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05054886 0,06752946 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05054886 0,06749198 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05054886 0,06745455 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,05054886 0,06741716 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05054886 0,06737981 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05054886 0,0673425 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05054886 0,06730523 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05054886 0,06726801 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05054886 0,06723082 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05054886 0,06719368 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05054886 0,06715657 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05054886 0,06711951 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05054886 0,06708249 ! blastocyst development GO:0001824 49 26 0,000 0,05054886 0,06704551 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05054886 0,06700857 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05054886 0,06697167 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05054886 0,06693481 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,05244202 0,06940346 ! neuron fate commitment GO:0048663 48 27 0,000 0,05244202 0,06936531 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05244202 0,0693272 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05244202 0,06928912 ! iron ion transport GO:0006826 59 27 0,000 0,05244202 0,0692511 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05244202 0,06921311 ! protein amino acid acylation GO:0043543 55 27 0,000 0,05244202 0,06917516 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05244202 0,06913726 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05244202 0,0690994 ! fat cell differentiation GO:0045444 50 27 0,000 0,05244202 0,06906157 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05244202 0,06902379 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,05244202 0,06898606 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05244202 0,06894836 ! autophagy GO:0006914 41 27 0,000 0,05244202 0,0689107 ! male gonad development GO:0008584 44 27 0,000 0,05244202 0,06887309 ! response to toxin GO:0009636 47 27 0,000 0,05244202 0,06883551 ! primary neural tube formation GO:0014020 51 27 0,000 0,05244202 0,06879798 ! base-excision repair GO:0006284 41 27 0,000 0,05244202 0,06876049 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05244202 0,06872304 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05244202 0,06868563 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05244202 0,06864826 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05244202 0,06861093 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05244202 0,06857364 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05244202 0,06853639 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05244202 0,06849918 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05244202 0,06846202 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05433147 0,07089019 ! circadian rhythm GO:0007623 50 28 0,000 0,05433147 0,07085176 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05433147 0,07081338 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05433147 0,07077504 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05433147 0,07073675 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05433147 0,07069849 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,05433147 0,07066027 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05433147 0,0706221 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05433147 0,07058397 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05433147 0,07054588 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05433147 0,07050782 ! synaptogenesis GO:0007416 42 28 0,000 0,05433147 0,07046981 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05433147 0,07043185 ! lipid oxidation GO:0034440 43 28 0,000 0,05433147 0,07039392 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05433147 0,07035603 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05433147 0,07031819 ! translational initiation GO:0006413 65 29 0,000 0,05621721 0,07271968 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,05621721 0,0726806 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,05621721 0,07264157 ! regulation of pH GO:0006885 43 29 0,000 0,05621721 0,07260258 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,05621721 0,07256363 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,05621721 0,07252472 ! catechol metabolic process GO:0009712 54 29 0,000 0,05621721 0,07248585 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,05621721 0,07244703 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,05621721 0,07240825 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,05621721 0,0723695 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,05621721 0,0723308 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,05621721 0,07229215 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,05621721 0,07225353 ! cell fate determination GO:0001709 60 29 0,000 0,05621721 0,07221495 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,05621721 0,07217642 ! detection of light stimulus GO:0009583 38 29 0,000 0,05621721 0,07213792 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,05621721 0,07209947 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,05621721 0,07206106 ! tissue homeostasis GO:0001894 48 29 0,000 0,05621721 0,07202269 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,05809925 0,07439425 ! zinc ion transport GO:0006829 45 30 0,000 0,05809925 0,07435468 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,05809925 0,07431515 ! cell junction assembly GO:0034329 78 30 0,000 0,05809925 0,07427567 ! regulation of innate immune response GO:0045088 51 30 0,000 0,05809925 0,07423622 ! acute-phase response GO:0006953 49 30 0,000 0,05809925 0,07419682 ! myofibril assembly GO:0030239 47 30 0,000 0,05809925 0,07415746 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,05809925 0,07411814 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,05809925 0,07407886 ! phospholipid transport GO:0015914 51 30 0,000 0,05809925 0,07403962 ! ensheathment of neurons GO:0007272 57 30 0,000 0,05809925 0,07400043 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,05809925 0,07396127 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,05809925 0,07392216 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,05809925 0,07388309 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,05809925 0,07384406 ! eye morphogenesis GO:0048592 60 30 0,000 0,05809925 0,07380507 ! regulation of B cell activation GO:0050864 50 30 0,000 0,05809925 0,07376612 ! response to heat GO:0009408 50 30 0,000 0,05809925 0,07372722 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05997761 0,0760707 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05997761 0,07603062 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05997761 0,07599059 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05997761 0,07595059 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05997761 0,07591064 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05997761 0,07587073 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05997761 0,07583086 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05997761 0,07579103 ! ovulation cycle process GO:0022602 49 31 0,000 0,05997761 0,07575125 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05997761 0,0757115 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,05997761 0,0756718 ! peptide transport GO:0015833 55 31 0,000 0,05997761 0,07563214 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05997761 0,07559252 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05997761 0,07555294 ! mesoderm formation GO:0001707 69 31 0,000 0,05997761 0,07551341 ! natural killer cell activation GO:0030101 45 31 0,000 0,05997761 0,07547391 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,05997761 0,07543446 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05997761 0,07539505 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05997761 0,07535568 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,05997761 0,07531635 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05997761 0,07527706 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06185228 0,07758946 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06185228 0,07754903 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06185228 0,07750864 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06185228 0,07746829 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06185228 0,07742798 ! spliceosome assembly GO:0000245 67 32 0,000 0,06185228 0,07738772 ! spindle organization GO:0007051 46 32 0,000 0,06185228 0,0773475 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06185228 0,07730732 ! metanephros development GO:0001656 74 32 0,000 0,06185228 0,07726718 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06185228 0,07722708 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06185228 0,07718702 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06185228 0,07714701 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06185228 0,07710704 ! muscle cell development GO:0055001 49 32 0,000 0,06185228 0,07706711 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06185228 0,07702722 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06185228 0,07698737 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06185228 0,07694756 ! ovulation cycle GO:0042698 51 32 0,000 0,06185228 0,07690779 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06185228 0,07686807 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06185228 0,07682838 ! hindbrain development GO:0030902 61 32 0,000 0,06185228 0,07678874 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06185228 0,07674914 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06185228 0,07670958 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,06185228 0,07667006 ! gene silencing GO:0016458 65 32 0,000 0,06185228 0,07663058 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06372327 0,07890797 ! post-embryonic development GO:0009791 69 33 0,000 0,06372327 0,07886738 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,06372327 0,07882683 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06372327 0,07878633 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,06372327 0,07874586 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06372327 0,07870544 ! formation of primary germ layer GO:0001704 72 33 0,000 0,06372327 0,07866506 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,06372327 0,07862471 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06372327 0,07858442 ! adult locomotory behavior GO:0008344 59 33 0,000 0,06372327 0,07854416 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,06372327 0,07850394 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06372327 0,07846376 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,0655906 0,08072173 ! glial cell differentiation GO:0010001 63 34 0,000 0,0655906 0,08068046 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,0655906 0,08063923 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,0655906 0,08059805 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,0655906 0,08055691 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,0655906 0,0805158 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,0655906 0,08047475 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,0655906 0,08043373 ! mismatch repair GO:0006298 46 34 0,000 0,0655906 0,08039275 ! spermatid development GO:0007286 63 34 0,000 0,0655906 0,08035182 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,0655906 0,08031093 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,0655906 0,08027008 ! placenta development GO:0001890 53 34 0,000 0,0655906 0,08022927 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,0655906 0,0801885 ! regulation of muscle development GO:0048634 70 35 0,000 0,06745426 0,08242506 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,06745426 0,08238322 ! negative regulation of secretion GO:0051048 63 35 0,000 0,06745426 0,08234143 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,06745426 0,08229967 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,06745426 0,08225796 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,06745426 0,08221629 ! odontogenesis GO:0042476 66 35 0,000 0,06745426 0,08217466 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,06745426 0,08213307 ! female gonad development GO:0008585 58 35 0,000 0,06745426 0,08209153 ! telencephalon development GO:0021537 68 35 0,000 0,06745426 0,08205003 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,06745426 0,08200856 ! cytokine production GO:0001816 59 35 0,000 0,06745426 0,08196715 ! neural tube formation GO:0001841 67 35 0,000 0,06745426 0,08192577 ! vesicle localization GO:0051648 64 35 0,000 0,06745426 0,08188443 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,06931427 0,08409991 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,06931427 0,08405752 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,06931427 0,08401518 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,06931427 0,08397287 ! cell junction organization GO:0034330 86 36 0,000 0,06931427 0,08393061 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,06931427 0,08388839 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,06931427 0,08384622 ! positive regulation of cell development GO:0010720 80 36 0,000 0,06931427 0,08380408 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,06931427 0,08376199 ! regulation of proteolysis GO:0030162 72 36 0,000 0,06931427 0,08371994 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,06931427 0,08367794 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,06931427 0,08363597 ! aerobic respiration GO:0009060 55 36 0,000 0,06931427 0,08359405 ! embryonic organ development GO:0048568 57 36 0,000 0,06931427 0,08355217 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,06931427 0,08351033 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,06931427 0,08346853 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07117063 0,08566109 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07117063 0,08561826 ! meiosis I GO:0007127 65 37 0,000 0,07117063 0,08557548 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07117063 0,08553273 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07117063 0,08549003 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07117063 0,08544737 ! organic anion transport GO:0015711 68 37 0,000 0,07117063 0,08540475 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07117063 0,08536218 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07117063 0,08531965 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07117063 0,08527716 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07117063 0,08523471 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07117063 0,0851923 ! glycogen metabolic process GO:0005977 61 37 0,000 0,07117063 0,08514994 ! pigment metabolic process GO:0042440 80 37 0,000 0,07117063 0,08510762 ! spermatid differentiation GO:0048515 66 37 0,000 0,07117063 0,08506534 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,07302335 0,08723643 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,07302335 0,08719314 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,07302335 0,08714989 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,07302335 0,08710668 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,07302335 0,08706351 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,07302335 0,08702039 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,07302335 0,08697731 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,07302335 0,08693427 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,07302335 0,08689128 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,07302335 0,08684833 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,07302335 0,08680542 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,07302335 0,08676255 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,07302335 0,08671973 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,07302335 0,08667695 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,07302335 0,08663421 ! glucan metabolic process GO:0044042 62 38 0,000 0,07302335 0,08659151 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,07487243 0,08874043 ! learning GO:0007612 77 39 0,000 0,07487243 0,08869673 ! ear morphogenesis GO:0042471 60 39 0,000 0,07487243 0,08865308 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,07487243 0,08860948 ! segmentation GO:0035282 67 39 0,000 0,07487243 0,08856591 ! ion transmembrane transport GO:0034220 66 39 0,000 0,07487243 0,08852239 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,07487243 0,08847891 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,07487243 0,08843548 ! RNA modification GO:0009451 57 39 0,000 0,07487243 0,08839208 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,07487243 0,08834873 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,07671789 0,09048198 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,07671789 0,09043765 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,07671789 0,09039336 ! feeding behavior GO:0007631 59 40 0,000 0,07671789 0,09034911 ! negative regulation of binding GO:0051100 72 40 0,000 0,07671789 0,09030491 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,07671789 0,09026075 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,07671789 0,09021663 ! maintenance of protein location GO:0045185 91 40 0,000 0,07671789 0,09017256 ! cytokinesis GO:0000910 72 40 0,000 0,07671789 0,09012853 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,07855972 0,09224729 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,07855972 0,09220229 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,07855972 0,09215733 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,07855972 0,09211242 ! gliogenesis GO:0042063 88 41 0,000 0,07855972 0,09206756 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,07855972 0,09202273 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,07855972 0,09197795 ! T cell differentiation GO:0030217 81 41 0,000 0,07855972 0,09193322 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,07855972 0,09188852 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,07855972 0,09184387 ! female gamete generation GO:0007292 61 41 0,000 0,07855972 0,09179927 ! polyol metabolic process GO:0019751 66 41 0,000 0,07855972 0,09175471 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,07855972 0,09171019 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08039795 0,0938106 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08039795 0,09376513 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08039795 0,0937197 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08039795 0,09367431 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08039795 0,09362897 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08039795 0,09358368 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08039795 0,09353842 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08039795 0,09349321 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,08039795 0,09344805 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,08223256 0,09553431 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,08223256 0,0954882 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,08223256 0,09544214 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,08223256 0,09539612 ! glucose transport GO:0015758 65 43 0,000 0,08223256 0,09535014 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,08223256 0,09530421 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,08223256 0,09525833 ! neural tube development GO:0021915 77 43 0,000 0,08223256 0,09521249 ! striated muscle contraction GO:0006941 77 43 0,000 0,08223256 0,09516669 ! phagocytosis GO:0006909 90 43 0,000 0,08223256 0,09512094 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,08223256 0,09507523 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,08406358 0,09714552 ! hexose transport GO:0008645 67 44 0,000 0,08406358 0,09709889 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,08406358 0,09705229 ! male sex differentiation GO:0046661 76 44 0,000 0,08406358 0,09700575 ! double-strand break repair GO:0006302 81 44 0,000 0,08406358 0,09695924 ! biopolymer methylation GO:0043414 84 44 0,000 0,08406358 0,09691278 ! B cell differentiation GO:0030183 107 44 0,000 0,08406358 0,09686637 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,08406358 0,09682 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,08406358 0,09677367 ! developmental growth GO:0048589 82 44 0,000 0,08406358 0,09672739 ! maintenance of location in cell GO:0051651 97 44 0,000 0,08406358 0,09668116 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,08589101 0,09873567 ! glycolysis GO:0006096 65 45 0,000 0,08589101 0,09868852 ! leukocyte migration GO:0050900 68 45 0,000 0,08589101 0,09864142 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,08589101 0,09859435 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,08589101 0,09854734 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,08589101 0,09850037 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,08589101 0,09845344 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,08589101 0,09840656 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,08589101 0,09835972 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,08589101 0,09831292 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,08589101 0,09826618 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,08771485 0,1003051 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,08771485 0,10025745 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,08771485 0,10020984 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,08771485 0,10016228 ! pigmentation GO:0043473 100 46 0,000 0,08771485 0,10011477 ! positive regulation of defense response GO:0031349 76 47 0,000 0,08953511 0,1021439 ! response to calcium ion GO:0051592 81 47 0,000 0,08953511 0,10209549 ! endosome transport GO:0016197 108 47 0,000 0,08953511 0,10204712 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,08953511 0,10199881 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,08953511 0,10195053 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,08953511 0,10190231 ! JNK cascade GO:0007254 91 47 0,000 0,08953511 0,10185413 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,08953511 0,10180599 ! methylation GO:0032259 90 47 0,000 0,08953511 0,1017579 ! mitochondrial transport GO:0006839 82 48 0,000 0,0913518 0,10377358 ! Notch signaling pathway GO:0007219 96 48 0,000 0,0913518 0,1037246 ! cellular component disassembly GO:0022411 86 48 0,000 0,0913518 0,10367568 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,0913518 0,1036268 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,0913518 0,10357796 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,0913518 0,10352917 ! activation of caspase activity GO:0006919 84 48 0,000 0,0913518 0,10348043 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,0913518 0,10343174 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,0913518 0,10338308 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,0913518 0,10333448 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,0913518 0,10328592 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,09316493 0,10528643 ! regulation of action potential GO:0001508 95 49 0,000 0,09316493 0,105237 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,09316493 0,10518762 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,09316493 0,10513828 ! regulation of ion transport GO:0043269 77 49 0,000 0,09316493 0,10508899 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,09316493 0,10503975 ! peptide metabolic process GO:0006518 76 49 0,000 0,09316493 0,10499055 ! response to temperature stimulus GO:0009266 76 49 0,000 0,09316493 0,10494139 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,09316493 0,10489229 ! endocrine system development GO:0035270 104 49 0,000 0,09316493 0,10484323 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,09316493 0,10479421 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,09316493 0,10474524 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,09316493 0,10469632 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,09316493 0,10464744 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,0949745 0,10663026 ! neuromuscular process GO:0050905 99 50 0,000 0,0949745 0,10658052 ! regulation of ossification GO:0030278 117 50 0,000 0,0949745 0,10653083 ! inner ear development GO:0048839 79 50 0,000 0,0949745 0,10648119 ! histone modification GO:0016570 91 50 0,000 0,0949745 0,1064316 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,0949745 0,10638205 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,0949745 0,10633255 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,0949745 0,10628309 ! positive regulation of binding GO:0051099 78 51 0,000 0,09678051 0,1082538 ! viral infectious cycle GO:0019058 99 51 0,000 0,09678051 0,10820349 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,09678051 0,10815324 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,09678051 0,10810303 ! excretion GO:0007588 83 51 0,000 0,09678051 0,10805286 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,09678051 0,10800275 ! chromatin remodeling GO:0006338 109 51 0,000 0,09678051 0,10795267 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,09678051 0,10790265 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,09678051 0,10785267 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,09678051 0,10780274 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,09678051 0,10775285 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,09678051 0,10770302 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,09858299 0,10965819 ! positive regulation of growth GO:0045927 90 52 0,000 0,09858299 0,10960752 ! covalent chromatin modification GO:0016569 101 52 0,000 0,09858299 0,10955689 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,09858299 0,10950631 ! amino acid activation GO:0043038 92 52 0,000 0,09858299 0,10945578 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,09858299 0,10940529 ! synapse organization GO:0050808 85 52 0,000 0,09858299 0,10935485 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10038192 0,11129904 ! RNA catabolic process GO:0006401 93 53 0,000 0,10038192 0,11124777 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10038192 0,11119655 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,10038192 0,11114538 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,10038192 0,11109426 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,10038192 0,11104318 ! cell maturation GO:0048469 100 53 0,000 0,10038192 0,11099215 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,10038192 0,11094116 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,10217733 0,11287358 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,10217733 0,11282178 ! cell recognition GO:0008037 85 54 0,000 0,10217733 0,11277003 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,10217733 0,11271832 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,10217733 0,11266666 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,10217733 0,11261505 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,10396921 0,11453751 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,10396921 0,11448509 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,10396921 0,11443272 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,10396921 0,1143804 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,10396921 0,11432812 ! aging GO:0007568 103 55 0,000 0,10396921 0,11427589 ! gastrulation GO:0007369 112 55 0,000 0,10396921 0,11422371 ! heart morphogenesis GO:0003007 97 55 0,000 0,10396921 0,11417158 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,10396921 0,11411949 ! RNA elongation GO:0006354 79 55 0,000 0,10396921 0,11406745 ! nuclear export GO:0051168 97 55 0,000 0,10396921 0,11401546 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,10396921 0,11396352 ! regulation of actin filament length GO:0030832 105 56 0,000 0,10575758 0,11587101 ! sensory perception of smell GO:0007608 80 56 0,000 0,10575758 0,11581827 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,10575758 0,11576558 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,10575758 0,11571293 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,10575758 0,11566033 ! regulation of DNA replication GO:0006275 101 56 0,000 0,10575758 0,11560778 ! proton transport GO:0015992 94 56 0,000 0,10575758 0,11555528 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,10754243 0,11745215 ! muscle fiber development GO:0048747 112 57 0,000 0,10754243 0,11739886 ! maintenance of location GO:0051235 118 57 0,000 0,10754243 0,11734562 ! hydrogen transport GO:0006818 97 58 0,000 0,10932379 0,11923528 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,10932379 0,11918126 ! regulation of endocytosis GO:0030100 91 58 0,000 0,10932379 0,11912728 ! adult behavior GO:0030534 99 58 0,000 0,10932379 0,11907335 ! positive regulation of secretion GO:0051047 95 59 0,000 0,11110164 0,120955 ! regulation of cellular component size GO:0032535 109 59 0,000 0,11110164 0,1209003 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,11110164 0,12084564 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,11110164 0,12079103 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,11110164 0,12073647 ! DNA catabolic process GO:0006308 86 59 0,000 0,11110164 0,12068196 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,11110164 0,12062751 ! establishment of organelle localization GO:0051656 109 59 0,000 0,11110164 0,1205731 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,11287601 0,1224435 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,11287601 0,12238832 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,11287601 0,12233319 ! regulation of heart contraction GO:0008016 110 60 0,000 0,11287601 0,12227811 ! camera-type eye development GO:0043010 116 60 0,000 0,11287601 0,12222308 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,11287601 0,1221681 ! kidney development GO:0001822 122 60 0,000 0,11287601 0,12211316 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,11464689 0,12397322 ! mesoderm development GO:0007498 119 61 0,000 0,11464689 0,12391753 ! tRNA processing GO:0008033 89 61 0,000 0,11464689 0,12386189 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,11464689 0,12380629 ! ear development GO:0043583 103 62 0,000 0,1164143 0,1256585 ! viral reproductive process GO:0022415 126 62 0,000 0,1164143 0,12560215 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,1164143 0,12554586 ! gonad development GO:0008406 98 62 0,000 0,1164143 0,12548961 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,1164143 0,12543341 ! regulation of mitosis GO:0007088 105 63 0,000 0,11817824 0,12727701 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,11817824 0,12722006 ! detection of external stimulus GO:0009581 91 63 0,000 0,11817824 0,12716317 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,11817824 0,12710632 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,11993871 0,12894215 ! cell redox homeostasis GO:0045454 102 64 0,000 0,11993871 0,12888456 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,11993871 0,12882703 ! single fertilization GO:0007338 75 64 0,000 0,11993871 0,12876954 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,12169573 0,13059765 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,12169573 0,13053942 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,12169573 0,13048125 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,12169573 0,13042313 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,12169573 0,13036506 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,1234493 0,1321847 ! actin filament organization GO:0007015 148 66 0,000 0,1234493 0,1321259 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,1234493 0,13206715 ! extracellular matrix organization GO:0030198 133 66 0,000 0,1234493 0,13200845 ! secondary metabolic process GO:0019748 116 66 0,000 0,1234493 0,13194981 ! developmental maturation GO:0021700 116 66 0,000 0,1234493 0,13189121 ! cell projection assembly GO:0030031 120 66 0,000 0,1234493 0,13183267 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,12519943 0,13364233 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,12519943 0,13358307 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,12519943 0,13352386 ! activation of MAPK activity GO:0000187 115 67 0,000 0,12519943 0,1334647 ! chromosome segregation GO:0007059 113 67 0,000 0,12519943 0,13340559 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,12519943 0,13334653 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,12519943 0,13328753 ! hexose catabolic process GO:0019320 104 67 0,000 0,12519943 0,13322858 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,12519943 0,13316968 ! adaptive immune response GO:0002250 119 67 0,000 0,12519943 0,13311083 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,12519943 0,13305204 ! amino acid transport GO:0006865 125 68 0,000 0,12694612 0,13484872 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,12694612 0,13478921 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,12694612 0,13472975 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,12694612 0,13467035 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,12694612 0,134611 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,12694612 0,1345517 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,12868938 0,13633934 ! negative regulation of cell size GO:0045792 134 69 0,000 0,12868938 0,13627933 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,12868938 0,13621937 ! urogenital system development GO:0001655 137 69 0,000 0,12868938 0,13615947 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,12868938 0,13609962 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,12868938 0,13603982 ! antigen processing and presentation GO:0019882 104 69 0,000 0,12868938 0,13598008 ! appendage morphogenesis GO:0035107 135 70 0,000 0,13042921 0,13775798 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,13216563 0,13953072 ! reproductive structure development GO:0048608 113 71 0,000 0,13216563 0,13946952 ! appendage development GO:0048736 136 71 0,000 0,13216563 0,13940838 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,13216563 0,13934729 ! B cell activation GO:0042113 160 71 0,000 0,13216563 0,13928625 ! regulation of immune effector process GO:0002697 137 71 0,000 0,13216563 0,13922527 ! acute inflammatory response GO:0002526 113 72 0,000 0,13389865 0,14098912 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,13389865 0,14092745 ! carbohydrate transport GO:0008643 110 72 0,000 0,13389865 0,14086583 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,13389865 0,14080426 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,13389865 0,14074274 ! learning or memory GO:0007611 147 73 0,000 0,13562825 0,14249851 ! regulation of blood pressure GO:0008217 125 73 0,000 0,13562825 0,14243631 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,13562825 0,14237416 ! fertilization GO:0009566 90 73 0,000 0,13562825 0,14231207 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,13735447 0,14406053 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,13735447 0,14399775 ! neurotransmitter transport GO:0006836 123 74 0,000 0,13735447 0,14393504 ! meiosis GO:0007126 121 74 0,000 0,13735447 0,14387237 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,13735447 0,14380977 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,13735447 0,14374721 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,13735447 0,14368472 ! eye development GO:0001654 143 74 0,000 0,13735447 0,14362227 ! organelle localization GO:0051640 136 74 0,000 0,13735447 0,14355988 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,13907729 0,14529742 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,13907729 0,14523435 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,13907729 0,14517135 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,13907729 0,14510839 ! meiotic cell cycle GO:0051321 122 75 0,000 0,13907729 0,14504549 ! rhythmic process GO:0048511 128 75 0,000 0,13907729 0,14498265 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,13907729 0,14491986 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,14079673 0,14664802 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,14079673 0,14658456 ! defense response to bacterium GO:0042742 89 76 0,000 0,14079673 0,14652116 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,14079673 0,14645781 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,14079673 0,14639452 ! regulation of catabolic process GO:0009894 161 76 0,000 0,14079673 0,14633128 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,14251279 0,14805085 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,14251279 0,14798695 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,14251279 0,14792311 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,14251279 0,14785932 ! blood coagulation GO:0007596 146 78 0,000 0,14422548 0,14957177 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,14422548 0,14950732 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,14422548 0,14944294 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,1459348 0,15114901 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,1459348 0,15108397 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,1459348 0,15101899 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,1459348 0,15095406 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,1459348 0,15088919 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,14764077 0,1525875 ! response to metal ion GO:0010038 140 80 0,000 0,14764077 0,15252198 ! muscle cell differentiation GO:0042692 159 80 0,000 0,14764077 0,15245652 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,14764077 0,15239112 ! protein import into nucleus GO:0006606 158 80 0,000 0,14764077 0,15232577 ! T cell activation GO:0042110 168 81 0,000 0,14934339 0,15401638 ! digestion GO:0007586 112 81 0,000 0,14934339 0,15395039 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,14934339 0,15388446 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,14934339 0,15381858 ! nuclear import GO:0051170 161 81 0,000 0,14934339 0,15375276 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,14934339 0,153687 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,15104267 0,15536924 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,15104267 0,15530284 ! response to nutrient GO:0007584 125 82 0,000 0,15104267 0,1552365 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,15104267 0,15517022 ! regulation of lyase activity GO:0051339 160 83 0,000 0,1527386 0,15684553 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,15443121 0,15851599 ! hemostasis GO:0007599 158 84 0,000 0,15443121 0,15844839 ! negative regulation of transport GO:0051051 153 84 0,000 0,15443121 0,15838085 ! negative regulation of growth GO:0045926 155 84 0,000 0,15443121 0,15831337 ! regulation of ligase activity GO:0051340 142 84 0,000 0,15443121 0,15824595 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,15443121 0,15817858 ! response to unfolded protein GO:0006986 131 85 0,000 0,15612049 0,1598408 ! nucleosome assembly GO:0006334 122 85 0,000 0,15612049 0,15977282 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,15612049 0,15970489 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,15612049 0,15963701 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,15780645 0,1612924 ! response to inorganic substance GO:0010035 153 86 0,000 0,15780645 0,16122391 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,15780645 0,16115548 ! chromatin assembly GO:0031497 124 86 0,000 0,15780645 0,16108711 ! tube morphogenesis GO:0035239 176 86 0,000 0,15780645 0,16101879 ! mitochondrion organization GO:0007005 148 86 0,000 0,15780645 0,16095054 ! alcohol catabolic process GO:0046164 130 86 0,000 0,15780645 0,16088234 ! amine transport GO:0015837 155 86 0,000 0,15780645 0,16081419 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,1594891 0,1624601 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,1594891 0,16239135 ! protein localization in nucleus GO:0034504 176 87 0,000 0,1594891 0,16232266 ! cellular respiration GO:0045333 135 88 0,000 0,16116844 0,16396248 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,16116844 0,16389318 ! regulation of DNA binding GO:0051101 155 88 0,000 0,16116844 0,16382394 ! regulation of neurological system process GO:0031644 148 88 0,000 0,16116844 0,16375476 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,16116844 0,16368563 ! cellular defense response GO:0006968 114 89 0,000 0,16284448 0,16531807 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,16284448 0,16524834 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,16284448 0,16517868 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,16451723 0,16680508 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,16451723 0,16673482 ! sex differentiation GO:0007548 145 90 0,000 0,16451723 0,16666461 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,16451723 0,16659447 ! sterol metabolic process GO:0016125 152 91 0,000 0,16618669 0,16821421 ! response to protein stimulus GO:0051789 149 91 0,000 0,16618669 0,16814348 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,16618669 0,1680728 ! regulation of defense response GO:0031347 149 92 0,000 0,16785288 0,16968656 ! nucleosome organization GO:0034728 138 92 0,000 0,16785288 0,1696153 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,16785288 0,16954409 ! vitamin metabolic process GO:0006766 139 92 0,000 0,16785288 0,16947294 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,16951579 0,17108011 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,16951579 0,17100838 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,16951579 0,17093671 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,17117543 0,17253795 ! female pregnancy GO:0007565 164 94 0,000 0,17117543 0,17246569 ! transcription initiation GO:0006352 153 94 0,000 0,17117543 0,1723935 ! regulation of T cell activation GO:0050863 158 94 0,000 0,17117543 0,17232137 ! forebrain development GO:0030900 188 95 0,000 0,17283181 0,17391607 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,17283181 0,17384336 ! leukocyte differentiation GO:0002521 202 96 0,000 0,17448493 0,17543282 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,17448493 0,17535954 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,17448493 0,17528632 ! detection of stimulus GO:0051606 151 96 0,000 0,17448493 0,17521316 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,1761348 0,17679614 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,1761348 0,17672241 ! protein ubiquitination GO:0016567 217 97 0,000 0,1761348 0,17664875 ! hormone metabolic process GO:0042445 157 97 0,000 0,1761348 0,17657514 ! response to virus GO:0009615 160 98 0,000 0,17778144 0,17815166 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,17778144 0,17807749 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,17778144 0,17800339 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,17942483 0,17957411 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,17942483 0,17949944 ! cell cycle arrest GO:0007050 213 100 0,000 0,181065 0,181065