pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1227-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of microtubule polymerization GO:0031116 15 7 2,000 1,848E-07 4,514E-04 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 2,000 2,953E-07 3,607E-04 ! regulation of microtubule polymerization GO:0031113 17 8 2,000 2,953E-07 2,405E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 2,000 8,667E-07 5,294E-04 ! positive regulation of protein polymerization GO:0032273 27 14 2,000 1,905E-06 9,307E-04 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 2,378E-06 9,682E-04 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 2,000 3,545E-06 1,237E-03 ! positive regulation of protein complex assembly GO:0031334 34 18 2,000 4,249E-06 1,297E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 6,898E-06 1,873E-03 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 1,046E-05 2,555E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 1,046E-05 2,323E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 1,506E-05 3,065E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 1,876E-05 3,526E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 2,302E-05 4,017E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,081E-05 5,018E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 3,081E-05 4,705E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 3,081E-05 4,428E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 3,949E-05 5,36E-03 ! regulation of microtubule-based process GO:0032886 86 37 2,000 3,949E-05 5,078E-03 ! transepithelial chloride transport GO:0030321 12 6 1,000 4,617E-05 5,639E-03 GO:0070633|transepithelial transport, ! mammary gland development GO:0030879 93 40 2,000 5,003E-05 5,82E-03 ! mesenchymal cell development GO:0014031 94 41 2,000 5,391E-05 5,987E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! epithelial cell differentiation GO:0030855 83 43 2,000 6,225E-05 6,612E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 6,456E-05 6,571E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 6,456E-05 6,309E-03 ! vesicle fusion GO:0006906 20 7 1,000 6,456E-05 6,066E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 8,598E-05 7,779E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 8,598E-05 7,502E-03 ! gas homeostasis GO:0033483 14 8 1,000 8,598E-05 7,243E-03 ! protein homooligomerization GO:0051260 84 49 2,000 9,224E-05 7,511E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,104E-04 8,702E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,104E-04 8,43E-03 ! regulation of protein polymerization GO:0032271 117 55 2,000 1,304E-04 9,65E-03 ! induction of an organ GO:0001759 17 10 1,000 1,379E-04 9,906E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,379E-04 9,623E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 1,527E-04 0,01036452 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,683E-04 0,01111281 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,953E-04 0,01255735 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,017E-04 0,01263704 ! developmental induction GO:0031128 22 12 1,000 2,017E-04 0,01232112 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 2,017E-04 0,0120206 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 2,047E-04 0,01190513 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 2,047E-04 0,01162827 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 2,242E-04 0,01244972 ! organelle fusion GO:0048284 36 13 1,000 2,381E-04 0,0129286 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,381E-04 0,01264755 ! gland morphogenesis GO:0022612 31 13 1,000 2,381E-04 0,01237845 ! lung development GO:0030324 165 69 2,000 2,558E-04 0,01301735 ! lipid localization GO:0010876 32 14 1,000 2,775E-04 0,01383625 GO:0019915|lipid storage, ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 2,783E-04 0,01359787 ! respiratory tube development GO:0030323 171 72 2,000 2,9E-04 0,01389332 ! respiratory system development GO:0060541 175 74 2,000 3,145E-04 0,01477323 ! lactation GO:0007595 30 15 1,000 3,198E-04 0,01474314 ! regulation of vasodilation GO:0042312 27 15 1,000 3,198E-04 0,01447012 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 1,000 3,651E-04 0,01621805 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,651E-04 0,01592844 ! protein oligomerization GO:0051259 149 79 2,000 3,812E-04 0,0163377 ! regulation of peptidase activity GO:0052547 150 82 2,000 4,253E-04 0,01791313 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 4,645E-04 0,01923211 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,755E-04 0,02343136 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 5,755E-04 0,02304724 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 5,755E-04 0,02267551 ! gland development GO:0048732 220 91 2,000 5,768E-04 0,02236753 ! lipid phosphorylation GO:0046834 43 21 1,000 6,353E-04 0,02425148 ! regulation of vasoconstriction GO:0019229 40 21 1,000 6,353E-04 0,02387838 ! inactivation of MAPK activity GO:0000188 45 22 1,000 6,981E-04 0,02583872 ! vasodilation GO:0042311 40 22 1,000 6,981E-04 0,02545307 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 6,981E-04 0,02507876 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 8,321E-04 0,0294626 ! membrane depolarization GO:0051899 45 24 1,000 8,321E-04 0,0290417 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 8,321E-04 0,02863266 ! vasculogenesis GO:0001570 49 25 1,000 9,035E-04 0,03065518 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 9,776E-04 0,03271748 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 9,776E-04 0,03227535 ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 9,776E-04 0,03184502 ! regulation of blood coagulation GO:0030193 46 26 1,000 9,776E-04 0,031426 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,055E-03 0,03346109 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,134E-03 0,03553245 ! vesicle docking GO:0048278 55 28 1,000 1,134E-03 0,03508267 ! sperm motility GO:0030317 37 28 1,000 1,134E-03 0,03464414 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 1,303E-03 0,03928629 ! regulation of coagulation GO:0050818 52 30 1,000 1,303E-03 0,03880719 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,482E-03 0,04361637 ! cholesterol homeostasis GO:0042632 60 33 1,000 1,576E-03 0,04582528 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 1,576E-03 0,04528616 ! cholesterol transport GO:0030301 62 34 1,000 1,672E-03 0,04750285 ! cell fate specification GO:0001708 56 34 1,000 1,672E-03 0,04695684 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 1,672E-03 0,04642324 ! membrane docking GO:0022406 69 35 1,000 1,772E-03 0,04862806 ! sterol transport GO:0015918 63 35 1,000 1,772E-03 0,04808775 ! calcium-mediated signaling GO:0019722 67 35 1,000 1,772E-03 0,04755931 ! tissue remodeling GO:0048771 78 37 1,000 1,978E-03 0,05253589 ! neutral lipid metabolic process GO:0006638 54 38 1,000 2,086E-03 0,05479576 GO:0006639|acylglycerol metabolic process, ! cellular response to insulin stimulus GO:0032869 85 38 1,000 2,086E-03 0,05421283 ! lipid homeostasis GO:0055088 75 40 1,000 2,309E-03 0,05938212 ! glycerol ether metabolic process GO:0006662 57 40 1,000 2,309E-03 0,05876355 ! Rho protein signal transduction GO:0007266 88 40 1,000 2,309E-03 0,05815774 ! organic ether metabolic process GO:0018904 59 42 1,000 2,543E-03 0,06339749 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 2,543E-03 0,06275711 ! regulation of tube size GO:0035150 76 43 1,000 2,664E-03 0,06508606 GO:0050880|regulation of blood vessel size, ! neuron migration GO:0001764 85 43 1,000 2,664E-03 0,06444165 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 2,914E-03 0,06979848 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 3,043E-03 0,07218043 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 3,043E-03 0,07148639 ! cell growth GO:0016049 90 46 1,000 3,043E-03 0,07080557 ! positive regulation of protein transport GO:0051222 80 46 1,000 3,043E-03 0,07013759 ! response to insulin stimulus GO:0032868 98 47 1,000 3,175E-03 0,07248761 ! positive regulation of cell cycle GO:0045787 96 48 1,000 3,309E-03 0,07485361 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 3,309E-03 0,07416688 ! vascular process in circulatory system GO:0003018 85 48 1,000 3,309E-03 0,07349264 ! response to estrogen stimulus GO:0043627 98 52 1,000 3,872E-03 0,08522575 ! vesicle organization GO:0016050 127 53 1,000 4,02E-03 0,08767733 ! activation of phospholipase C activity GO:0007202 110 54 1,000 4,169E-03 0,09014118 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 1,000 4,169E-03 0,08935047 ! membrane fusion GO:0006944 122 54 1,000 4,169E-03 0,08857351 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 4,322E-03 0,09101993 ! response to UV GO:0009411 120 55 1,000 4,322E-03 0,09024199 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 4,634E-03 0,09594693 ! chloride transport GO:0006821 102 57 1,000 4,634E-03 0,09514066 ! regulation of phospholipase activity GO:0010517 113 57 1,000 4,634E-03 0,09434782 ! regulation of intracellular transport GO:0032386 108 57 1,000 4,634E-03 0,09356808 ! positive regulation of cell migration GO:0030335 137 58 1,000 4,794E-03 0,09600623 ! positive regulation of lipase activity GO:0060193 115 58 1,000 4,794E-03 0,09522569 ! lipid modification GO:0030258 112 60 1,000 5,122E-03 0,10091379 ! multicellular organism reproduction GO:0032504 123 65 1,000 5,985E-03 0,11697275 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 157 65 1,000 5,985E-03 0,11604439 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 6,165E-03 0,1185937 ! regulation of lipase activity GO:0060191 137 68 1,000 6,533E-03 0,12467958 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 6,72E-03 0,12726141 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 6,72E-03 0,12628248 ! negative regulation of kinase activity GO:0033673 145 70 1,000 6,91E-03 0,12885794 ! cAMP-mediated signaling GO:0019933 124 71 1,000 7,102E-03 0,13143917 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 7,297E-03 0,13402586 ! regulation of caspase activity GO:0043281 136 74 1,000 7,693E-03 0,14025342 ! negative regulation of transferase activity GO:0051348 155 74 1,000 7,693E-03 0,13921451 ! axon guidance GO:0007411 162 75 1,000 7,895E-03 0,14181592 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 8,306E-03 0,14810486 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 8,306E-03 0,14703164 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 8,726E-03 0,15335833 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 8,831E-03 0,15410776 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 8,831E-03 0,1530148 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 8,831E-03 0,15193723 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 8,831E-03 0,15087473 ! positive regulation of helicase activity GO:0051096 12 5 0,000 8,831E-03 0,14982699 ! neuron fate determination GO:0048664 7 5 0,000 8,831E-03 0,1487937 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,831E-03 0,14777456 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 8,831E-03 0,14676929 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 8,831E-03 0,14577761 ! polyol transport GO:0015791 12 5 0,000 8,831E-03 0,14479924 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 8,831E-03 0,14383391 ! response to superoxide GO:0000303 10 5 0,000 8,831E-03 0,14288137 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,831E-03 0,14194136 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 8,831E-03 0,14101364 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 8,831E-03 0,14009796 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 8,831E-03 0,13919411 ! female meiosis GO:0007143 10 5 0,000 8,831E-03 0,13830184 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 8,831E-03 0,13742093 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 8,831E-03 0,13655118 ! hypothalamus development GO:0021854 9 5 0,000 8,831E-03 0,13569237 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 8,831E-03 0,13484429 ! cobalt ion transport GO:0006824 11 5 0,000 8,831E-03 0,13400675 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 8,831E-03 0,13317955 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 8,831E-03 0,13236249 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 8,831E-03 0,1315554 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 8,831E-03 0,1307581 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 8,831E-03 0,1299704 ! embryonic camera-type eye development GO:0031076 12 5 0,000 8,831E-03 0,12919213 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 8,831E-03 0,12842313 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,831E-03 0,12766323 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 8,831E-03 0,12691227 ! transposition GO:0032196 9 5 0,000 8,831E-03 0,1261701 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 8,831E-03 0,12543655 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 8,831E-03 0,12471148 ! negative chemotaxis GO:0050919 16 5 0,000 8,831E-03 0,12399475 ! positive regulation of histone modification GO:0031058 6 5 0,000 8,831E-03 0,12328621 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 8,831E-03 0,12258572 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 8,831E-03 0,12189314 ! behavioral response to pain GO:0048266 10 5 0,000 8,831E-03 0,12120835 ! clathrin coat assembly GO:0048268 15 5 0,000 8,831E-03 0,12053121 ! Notch receptor processing GO:0007220 11 5 0,000 8,831E-03 0,11986159 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,831E-03 0,11919937 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 8,831E-03 0,11854443 ! micturition GO:0060073 9 5 0,000 8,831E-03 0,11789665 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 8,831E-03 0,1172559 ! copulation GO:0007620 9 5 0,000 8,831E-03 0,11662209 ! glial cell fate commitment GO:0021781 14 5 0,000 8,831E-03 0,11599509 ! protein maturation by protein folding GO:0022417 14 5 0,000 8,831E-03 0,11537479 ! bioluminescence GO:0008218 9 5 0,000 8,831E-03 0,1147611 ! spermidine metabolic process GO:0008216 7 5 0,000 8,831E-03 0,1141539 ! regulation of potassium ion transport GO:0043266 10 5 0,000 8,831E-03 0,11355309 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 8,831E-03 0,11295857 ! apoptotic cell clearance GO:0043277 23 5 0,000 8,831E-03 0,11237024 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 8,831E-03 0,11178801 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 8,831E-03 0,11121179 ! lipoprotein particle clearance GO:0034381 10 5 0,000 8,831E-03 0,11064147 ! grooming behavior GO:0007625 6 5 0,000 8,831E-03 0,11007697 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 8,831E-03 0,1095182 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 8,831E-03 0,10896508 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 8,831E-03 0,10841752 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,831E-03 0,10787543 ! response to protozoan GO:0001562 13 5 0,000 8,831E-03 0,10733874 ! positive regulation of glycolysis GO:0045821 13 5 0,000 8,831E-03 0,10680736 ! lymph vessel development GO:0001945 10 5 0,000 8,831E-03 0,10628121 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 8,831E-03 0,10576023 ! endochondral ossification GO:0001958 17 5 0,000 8,831E-03 0,10524432 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 8,831E-03 0,10473343 ! single strand break repair GO:0000012 8 5 0,000 8,831E-03 0,10422747 ! parathyroid gland development GO:0060017 14 5 0,000 8,831E-03 0,10372638 ! anagen GO:0042640 7 5 0,000 8,831E-03 0,10323008 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 8,831E-03 0,10273851 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 8,831E-03 0,10225159 ! cytokine secretion GO:0050663 15 5 0,000 8,831E-03 0,10176928 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 8,831E-03 0,10129149 ! ceramide catabolic process GO:0046514 7 5 0,000 8,831E-03 0,10081816 ! skeletal myofibril assembly GO:0014866 12 5 0,000 8,831E-03 0,10034924 ! smooth muscle tissue development GO:0048745 32 5 0,000 8,831E-03 0,09988466 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,831E-03 0,09942436 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 8,831E-03 0,09896829 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 8,831E-03 0,09851638 ! cardiac muscle fiber development GO:0048739 12 5 0,000 8,831E-03 0,09806857 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,831E-03 0,09762482 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 8,831E-03 0,09718507 ! neutrophil mediated immunity GO:0002446 7 5 0,000 8,831E-03 0,09674927 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 8,831E-03 0,09631735 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 8,831E-03 0,09588927 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 8,831E-03 0,09546498 ! glycine biosynthetic process GO:0006545 7 5 0,000 8,831E-03 0,09504443 ! microvillus organization GO:0032528 8 5 0,000 8,831E-03 0,09462757 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 8,831E-03 0,09421435 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 8,831E-03 0,09380472 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 8,831E-03 0,09339864 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 8,831E-03 0,09299606 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 8,831E-03 0,09259694 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 8,831E-03 0,09220122 ! polyol catabolic process GO:0046174 9 5 0,000 8,831E-03 0,09180888 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 8,831E-03 0,09141986 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 8,831E-03 0,09103412 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 8,831E-03 0,09065162 ! muscle cell migration GO:0014812 8 5 0,000 8,831E-03 0,09027233 ! mitochondrial fission GO:0000266 8 5 0,000 8,831E-03 0,08989619 ! sister chromatid cohesion GO:0007062 15 5 0,000 8,831E-03 0,08952318 ! response to tumor necrosis factor GO:0034612 10 5 0,000 8,831E-03 0,08915325 ! mRNA transcription GO:0009299 10 5 0,000 8,831E-03 0,08878636 ! nerve growth factor processing GO:0032455 9 5 0,000 8,831E-03 0,08842248 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 8,831E-03 0,08806158 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 8,831E-03 0,0877036 ! anaerobic glycolysis GO:0019642 6 5 0,000 8,831E-03 0,08734853 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 8,831E-03 0,08699632 ! monocyte activation GO:0042117 10 5 0,000 8,831E-03 0,08664693 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 8,831E-03 0,08630035 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 8,831E-03 0,08595652 ! response to food GO:0032094 6 5 0,000 8,831E-03 0,08561542 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 8,831E-03 0,08527702 ! positive regulation of transporter activity GO:0032411 8 5 0,000 8,831E-03 0,08494128 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 8,831E-03 0,08460818 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,831E-03 0,08427768 ! forebrain neuron development GO:0021884 13 5 0,000 8,831E-03 0,08394975 ! lipoprotein catabolic process GO:0042159 11 5 0,000 8,831E-03 0,08362437 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 8,831E-03 0,08330149 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 8,831E-03 0,0829811 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 8,831E-03 0,08266317 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,831E-03 0,08234766 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 8,831E-03 0,08203455 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 8,831E-03 0,08172381 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 8,831E-03 0,08141542 ! lipid glycosylation GO:0030259 7 5 0,000 8,831E-03 0,08110935 ! nucleobase transport GO:0015851 6 5 0,000 8,831E-03 0,08080557 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,831E-03 0,08050405 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 8,831E-03 0,08020478 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 8,831E-03 0,07990773 ! basic amino acid transport GO:0015802 12 5 0,000 8,831E-03 0,07961286 ! cellular glucose homeostasis GO:0001678 6 5 0,000 8,831E-03 0,07932017 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 8,831E-03 0,07902962 ! actin nucleation GO:0045010 11 5 0,000 8,831E-03 0,07874119 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,831E-03 0,07845486 ! depurination GO:0045007 5 5 0,000 8,831E-03 0,0781706 ! depyrimidination GO:0045008 10 5 0,000 8,831E-03 0,0778884 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,831E-03 0,07760822 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,831E-03 0,07733006 ! G2/M transition checkpoint GO:0031576 8 5 0,000 8,831E-03 0,07705388 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 8,831E-03 0,07677967 ! zinc ion homeostasis GO:0055069 9 5 0,000 8,831E-03 0,0765074 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 8,831E-03 0,07623705 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 8,831E-03 0,07596861 ! forebrain morphogenesis GO:0048853 13 5 0,000 8,831E-03 0,07570206 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 8,831E-03 0,07543736 ! activated T cell proliferation GO:0050798 16 5 0,000 8,831E-03 0,07517452 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 8,831E-03 0,07491349 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 8,831E-03 0,07465428 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 8,831E-03 0,07439685 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,831E-03 0,07414119 ! gamma-delta T cell activation GO:0046629 6 5 0,000 8,831E-03 0,07388728 ! response to arsenic GO:0046685 11 5 0,000 8,831E-03 0,07363511 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 8,831E-03 0,07338465 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 8,831E-03 0,07313589 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 8,831E-03 0,07288881 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 8,831E-03 0,07264339 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 8,831E-03 0,07239962 ! response to mercury ion GO:0046689 8 5 0,000 8,831E-03 0,07215748 ! response to cadmium ion GO:0046686 7 5 0,000 8,831E-03 0,07191695 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 8,831E-03 0,07167803 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 8,831E-03 0,07144068 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 8,831E-03 0,07120491 ! bile acid biosynthetic process GO:0006699 7 5 0,000 8,831E-03 0,07097068 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 8,831E-03 0,07073799 ! ganglioside catabolic process GO:0006689 12 5 0,000 8,831E-03 0,07050682 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 8,831E-03 0,07027715 ! decidualization GO:0046697 11 5 0,000 8,831E-03 0,07004898 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 8,831E-03 0,06982229 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 8,831E-03 0,06959705 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 8,831E-03 0,06937327 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 8,831E-03 0,06915092 ! embryonic cleavage GO:0040016 6 5 0,000 8,831E-03 0,06892999 ! peroxisome fission GO:0016559 5 5 0,000 8,831E-03 0,06871047 ! histone demethylation GO:0016577 13 5 0,000 8,831E-03 0,06849234 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 8,831E-03 0,06827559 ! mitotic recombination GO:0006312 9 5 0,000 8,831E-03 0,06806021 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 8,831E-03 0,06784618 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 8,831E-03 0,0676335 ! metaphase plate congression GO:0051310 7 5 0,000 8,831E-03 0,06742214 ! regulation of sterol transport GO:0032371 7 5 0,000 8,831E-03 0,06721211 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 8,831E-03 0,06700337 ! enteric nervous system development GO:0048484 8 5 0,000 8,831E-03 0,06679593 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 8,831E-03 0,06658977 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 8,831E-03 0,06638488 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 8,831E-03 0,06618125 ! muscle cell proliferation GO:0033002 12 5 0,000 8,831E-03 0,06597886 ! skeletal muscle regeneration GO:0043403 8 5 0,000 8,831E-03 0,0657777 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 8,831E-03 0,06557777 ! B cell homeostasis GO:0001782 13 5 0,000 8,831E-03 0,06537905 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 8,831E-03 0,06518153 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 8,831E-03 0,0649852 ! metaphase GO:0051323 11 5 0,000 8,831E-03 0,06479005 ! melatonin biosynthetic process GO:0030187 7 5 0,000 8,831E-03 0,06459607 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 8,831E-03 0,06440324 ! cellular response to nutrient GO:0031670 8 5 0,000 8,831E-03 0,06421157 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 8,831E-03 0,06402103 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 8,831E-03 0,06383162 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 8,831E-03 0,06364332 ! regulation of hair follicle development GO:0051797 10 5 0,000 8,831E-03 0,06345614 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 8,831E-03 0,06327005 ! response to redox state GO:0051775 6 5 0,000 8,831E-03 0,06308505 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 8,831E-03 0,06290113 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 8,831E-03 0,06271827 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 8,831E-03 0,06253648 ! brown fat cell differentiation GO:0050873 7 5 0,000 8,831E-03 0,06235574 ! regulation of telomerase activity GO:0051972 7 5 0,000 8,831E-03 0,06217604 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,831E-03 0,06199737 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 8,831E-03 0,06181973 ! porphyrin catabolic process GO:0006787 12 5 0,000 8,831E-03 0,0616431 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 8,831E-03 0,06146748 ! striatum development GO:0021756 14 5 0,000 8,831E-03 0,06129286 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 8,831E-03 0,06111922 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 8,831E-03 0,06094657 ! glial cell migration GO:0008347 10 5 0,000 8,831E-03 0,06077489 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 8,831E-03 0,06060418 ! neural plate morphogenesis GO:0001839 7 5 0,000 8,831E-03 0,06043442 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 8,831E-03 0,0602656 ! somatic stem cell maintenance GO:0035019 15 5 0,000 8,831E-03 0,06009773 ! T cell activation during immune response GO:0002286 9 5 0,000 8,831E-03 0,0599308 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 8,831E-03 0,05976478 ! negative regulation of lipase activity GO:0060192 8 5 0,000 8,831E-03 0,05959969 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 8,831E-03 0,0594355 ! neuroprotection GO:0043526 8 5 0,000 8,831E-03 0,05927222 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 8,831E-03 0,05910983 ! regulation of sensory perception GO:0051931 8 5 0,000 8,831E-03 0,05894832 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 8,831E-03 0,0587877 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 8,831E-03 0,05862795 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 8,831E-03 0,05846907 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 8,831E-03 0,05831104 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 8,831E-03 0,05815387 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 8,831E-03 0,05799754 ! sequestering of calcium ion GO:0051208 7 5 0,000 8,831E-03 0,05784205 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 8,831E-03 0,0576874 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 8,831E-03 0,05753356 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 8,831E-03 0,05738055 ! spindle assembly GO:0051225 6 5 0,000 8,831E-03 0,05722835 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 8,831E-03 0,05707695 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 8,831E-03 0,05692635 ! protein palmitoylation GO:0018345 12 5 0,000 8,831E-03 0,05677654 ! drug metabolic process GO:0017144 7 5 0,000 8,831E-03 0,05662752 ! stem cell division GO:0017145 11 5 0,000 8,831E-03 0,05647928 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 8,831E-03 0,05633182 ! organ regeneration GO:0031100 7 5 0,000 8,831E-03 0,05618512 ! carnitine metabolic process GO:0009437 8 5 0,000 8,831E-03 0,05603919 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 8,831E-03 0,05589401 ! response to hypoxia GO:0001666 178 81 1,000 9,155E-03 0,05779359 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 9,155E-03 0,05764464 ! response to drug GO:0042493 149 83 1,000 9,594E-03 0,06025226 ! response to oxygen levels GO:0070482 183 83 1,000 9,594E-03 0,06009777 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 9,594E-03 0,05994407 GO:0045937|positive regulation of phosphate metabolic process, ! inorganic anion transport GO:0015698 156 83 1,000 9,594E-03 0,05979115 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01004203 0,06242411 ! regulation of protein transport GO:0051223 165 87 1,000 0,01049921 0,06510046 GO:0070201|regulation of establishment of protein localization, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01058844 0,06548746 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01058844 0,06532209 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01058844 0,06515755 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01058844 0,06499384 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01058844 0,06483095 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01058844 0,06466887 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01058844 0,0645076 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01058844 0,06434713 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01058844 0,06418746 ! response to oxygen radical GO:0000305 11 6 0,000 0,01058844 0,06402858 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01058844 0,06387049 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01058844 0,06371317 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01058844 0,06355663 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01058844 0,06340085 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01058844 0,06324584 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01058844 0,06309158 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01058844 0,06293807 ! forebrain regionalization GO:0021871 9 6 0,000 0,01058844 0,06278531 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01058844 0,06263329 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01058844 0,062482 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01058844 0,06233144 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01058844 0,0621816 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01058844 0,06203249 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01058844 0,06188408 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01058844 0,06173639 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01058844 0,0615894 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01058844 0,06144311 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01058844 0,06129751 ! malate metabolic process GO:0006108 13 6 0,000 0,01058844 0,06115259 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01058844 0,06100837 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01058844 0,06086482 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01058844 0,06072194 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01058844 0,06057974 ! protein refolding GO:0042026 15 6 0,000 0,01058844 0,06043819 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01058844 0,06029731 ! opsonization GO:0008228 8 6 0,000 0,01058844 0,06015709 ! mating behavior GO:0007617 7 6 0,000 0,01058844 0,06001751 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01058844 0,05987858 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01058844 0,05974029 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01058844 0,05960264 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01058844 0,05946563 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01058844 0,05932924 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01058844 0,05919347 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01058844 0,05905833 ! toxin metabolic process GO:0009404 11 6 0,000 0,01058844 0,0589238 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01058844 0,05878988 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01058844 0,05865657 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01058844 0,05852386 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01058844 0,05839175 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01058844 0,05826024 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01058844 0,05812932 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01058844 0,05799898 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01058844 0,05786923 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01058844 0,05774006 ! thymic T cell selection GO:0045061 16 6 0,000 0,01058844 0,05761146 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01058844 0,05748344 ! protein lipoylation GO:0009249 10 6 0,000 0,01058844 0,05735598 ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01058844 0,05722909 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01058844 0,05710275 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01058844 0,05697698 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01058844 0,05685175 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01058844 0,05672708 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01058844 0,05660295 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01058844 0,05647936 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01058844 0,05635631 ! hyperosmotic response GO:0006972 10 6 0,000 0,01058844 0,0562338 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01058844 0,05611182 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01058844 0,05599036 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01058844 0,05586943 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01058844 0,05574902 ! urea metabolic process GO:0019627 7 6 0,000 0,01058844 0,05562913 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01058844 0,05550976 ! neutrophil activation GO:0042119 7 6 0,000 0,01058844 0,05539089 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01058844 0,05527254 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01058844 0,05515468 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01058844 0,05503733 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01058844 0,05492048 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01058844 0,05480413 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01058844 0,05468826 ! neuron apoptosis GO:0051402 15 6 0,000 0,01058844 0,05457288 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01058844 0,05445799 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01058844 0,05434359 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01058844 0,05422966 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01058844 0,05411621 ! carnitine transport GO:0015879 10 6 0,000 0,01058844 0,05400323 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01058844 0,05389072 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01058844 0,05377868 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01058844 0,05366711 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01058844 0,053556 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01058844 0,05344535 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01058844 0,05333515 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01058844 0,05322541 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01058844 0,05311611 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01058844 0,05300727 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01058844 0,05289887 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01058844 0,05279091 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01058844 0,0526834 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01058844 0,05257632 ! response to UV-C GO:0010225 14 6 0,000 0,01058844 0,05246967 ! astrocyte development GO:0014002 16 6 0,000 0,01058844 0,05236346 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01058844 0,05225767 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01058844 0,05215231 ! interaction with symbiont GO:0051702 14 6 0,000 0,01058844 0,05204738 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01058844 0,05194287 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01058844 0,05183877 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01058844 0,05173509 ! response to copper ion GO:0046688 10 6 0,000 0,01058844 0,05163183 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01058844 0,05152898 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01058844 0,05142654 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01058844 0,0513245 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01058844 0,05122287 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01058844 0,05112163 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01058844 0,0510208 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01058844 0,05092037 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01058844 0,05082033 ! hair follicle maturation GO:0048820 8 6 0,000 0,01058844 0,05072068 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01058844 0,05062142 ! Schwann cell development GO:0014044 15 6 0,000 0,01058844 0,05052255 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01058844 0,05042407 ! response to pheromone GO:0019236 6 6 0,000 0,01058844 0,05032597 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01058844 0,05022825 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01058844 0,05013091 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01058844 0,05003394 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01058844 0,04993735 ! subpallium development GO:0021544 15 6 0,000 0,01058844 0,04984113 ! neural tube patterning GO:0021532 8 6 0,000 0,01058844 0,04974528 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01058844 0,0496498 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01058844 0,04955469 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01058844 0,04945994 ! G2 phase GO:0051319 16 6 0,000 0,01058844 0,04936555 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01058844 0,04927152 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01058844 0,04917785 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01058844 0,04908453 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01058844 0,04899157 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01058844 0,04889896 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01058844 0,04880669 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01058844 0,04871478 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01058844 0,04862321 ! receptor internalization GO:0031623 11 6 0,000 0,01058844 0,04853198 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01058844 0,0484411 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01058844 0,04835056 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01058844 0,04826035 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01058844 0,04817048 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01058844 0,04808094 ! protein deubiquitination GO:0016579 16 6 0,000 0,01058844 0,04799174 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01058844 0,04790287 ! protein destabilization GO:0031648 9 6 0,000 0,01058844 0,04781432 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01058844 0,0477261 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01058844 0,04763821 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01058844 0,04755064 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01058844 0,04746339 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01058844 0,04737646 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01058844 0,04728985 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01058844 0,04720355 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01058844 0,04711757 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01058844 0,0470319 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01058844 0,04694655 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01058844 0,0468615 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01058844 0,04677676 ! neural plate development GO:0001840 9 6 0,000 0,01058844 0,04669232 ! catecholamine transport GO:0051937 9 6 0,000 0,01058844 0,04660819 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01058844 0,04652437 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01058844 0,04644084 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01058844 0,04635761 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01058844 0,04627468 ! maternal placenta development GO:0001893 12 6 0,000 0,01058844 0,04619205 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01058844 0,04610971 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01058844 0,04602766 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01058844 0,04594591 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01058844 0,04586445 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01058844 0,04578327 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01058844 0,04570238 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01058844 0,04562178 GO:0055081|anion homeostasis, ! ossification GO:0001503 205 91 1,000 0,01144078 0,04920743 ! bone development GO:0060348 206 92 1,000 0,01168178 0,05015571 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,01192502 0,05111022 ! regulation of membrane potential GO:0042391 179 94 1,000 0,01217048 0,05207088 ! tRNA transcription GO:0009304 17 7 0,000 0,01234241 0,05271419 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01234241 0,0526222 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01234241 0,05253052 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01234241 0,05243916 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01234241 0,05234812 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01234241 0,0522574 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01234241 0,05216699 ! sleep GO:0030431 16 7 0,000 0,01234241 0,05207689 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01234241 0,0519871 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01234241 0,05189762 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01234241 0,05180845 ! prostate gland development GO:0030850 14 7 0,000 0,01234241 0,05171959 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01234241 0,05163103 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01234241 0,05154277 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01234241 0,05145481 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01234241 0,05136715 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01234241 0,0512798 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01234241 0,05119273 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01234241 0,05110597 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01234241 0,05101949 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01234241 0,05093331 ! glycolipid transport GO:0046836 11 7 0,000 0,01234241 0,05084742 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01234241 0,05076182 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01234241 0,0506765 ! neuron adhesion GO:0007158 14 7 0,000 0,01234241 0,05059148 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01234241 0,05050673 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01234241 0,05042227 ! mRNA stabilization GO:0048255 18 7 0,000 0,01234241 0,0503381 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01234241 0,0502542 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01234241 0,05017058 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01234241 0,05008724 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01234241 0,05000418 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01234241 0,04992139 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01234241 0,04983888 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01234241 0,04975663 ! lipoprotein transport GO:0042953 14 7 0,000 0,01234241 0,04967466 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01234241 0,04959296 ! rhythmic behavior GO:0007622 17 7 0,000 0,01234241 0,04951153 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01234241 0,04943036 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01234241 0,04934946 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01234241 0,04926882 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01234241 0,04918845 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01234241 0,04910834 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01234241 0,04902849 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01234241 0,0489489 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01234241 0,04886956 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01234241 0,04879048 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01234241 0,04871166 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01234241 0,0486331 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01234241 0,04855478 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01234241 0,04847672 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01234241 0,04839891 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01234241 0,04832135 ! spinal cord patterning GO:0021511 14 7 0,000 0,01234241 0,04824403 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01234241 0,04816696 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01234241 0,04809014 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01234241 0,04801357 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01234241 0,04793723 ! adrenal gland development GO:0030325 17 7 0,000 0,01234241 0,04786114 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01234241 0,04778529 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01234241 0,04770968 ! ovulation GO:0030728 10 7 0,000 0,01234241 0,04763431 ! adenohypophysis development GO:0021984 11 7 0,000 0,01234241 0,04755918 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01234241 0,04748428 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01234241 0,04740962 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01234241 0,0473352 ! microtubule nucleation GO:0007020 21 7 0,000 0,01234241 0,047261 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01234241 0,04718704 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01234241 0,04711331 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01234241 0,04703981 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01234241 0,04696654 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01234241 0,0468935 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01234241 0,04682068 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01234241 0,04674809 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01234241 0,04667573 ! galactose metabolic process GO:0006012 13 7 0,000 0,01234241 0,04660359 ! response to dietary excess GO:0002021 8 7 0,000 0,01234241 0,04653167 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01234241 0,04645997 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01234241 0,04638849 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01234241 0,04631723 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01234241 0,0462462 ! organ growth GO:0035265 15 7 0,000 0,01234241 0,04617537 ! nucleoside transport GO:0015858 11 7 0,000 0,01234241 0,04610477 ! nucleoside salvage GO:0043174 11 7 0,000 0,01234241 0,04603438 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01234241 0,04596421 ! male sex determination GO:0030238 15 7 0,000 0,01234241 0,04589425 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01234241 0,0458245 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01234241 0,04575496 ! parturition GO:0007567 16 7 0,000 0,01234241 0,04568564 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01234241 0,04561652 ! rRNA modification GO:0000154 14 7 0,000 0,01234241 0,04554761 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01234241 0,04547891 ! spindle checkpoint GO:0031577 16 7 0,000 0,01234241 0,04541042 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01234241 0,04534213 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01234241 0,04527405 ! monocyte differentiation GO:0030224 16 7 0,000 0,01234241 0,04520618 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01234241 0,0451385 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01234241 0,04507103 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01234241 0,04500376 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01234241 0,04493669 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01234241 0,04486982 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01234241 0,04480315 ! fibrinolysis GO:0042730 11 7 0,000 0,01234241 0,04473668 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01234241 0,0446704 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01234241 0,04460432 ! eating behavior GO:0042755 8 7 0,000 0,01234241 0,04453843 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01234241 0,04447274 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01234241 0,04440725 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01234241 0,04434194 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01234241 0,04427683 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01234241 0,04421191 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01234241 0,04414717 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01234241 0,04408263 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01234241 0,04401828 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01234241 0,04395411 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01234241 0,04389013 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01234241 0,04382634 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01234241 0,04376273 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01234241 0,0436993 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01234241 0,04363606 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01234241 0,04357301 ! histone ubiquitination GO:0016574 9 7 0,000 0,01234241 0,04351013 ! regulation of meiosis GO:0040020 12 7 0,000 0,01234241 0,04344743 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01234241 0,04338492 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01234241 0,04332259 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01234241 0,04326043 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01234241 0,04319845 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01234241 0,04313665 ! transcription termination GO:0006353 14 7 0,000 0,01234241 0,04307503 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01234241 0,04301358 ! anaphase GO:0051322 18 7 0,000 0,01234241 0,04295231 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01234241 0,04289121 ! axonal fasciculation GO:0007413 19 7 0,000 0,01234241 0,04283028 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01234241 0,04276953 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01234241 0,04270895 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01234241 0,04264854 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01234241 0,0425883 ! diuresis GO:0030146 12 7 0,000 0,01234241 0,04252824 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01234241 0,04246834 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01234241 0,04240861 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01234241 0,04234904 ! antibiotic transport GO:0042891 9 7 0,000 0,01234241 0,04228965 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01234241 0,04223042 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01234241 0,04217136 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01234241 0,04211246 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01234241 0,04205372 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01234241 0,04199515 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01234241 0,04193674 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01234241 0,0418785 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01234241 0,04182042 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01234241 0,04176249 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01234241 0,04170473 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01234241 0,04164713 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01234241 0,04158968 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01234241 0,0415324 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01234241 0,04147527 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01234241 0,0414183 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01234241 0,04136148 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01234241 0,04130482 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01234241 0,04124832 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01234241 0,04119197 ! muscle adaptation GO:0043500 13 7 0,000 0,01234241 0,04113577 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01234241 0,04107973 ! retina homeostasis GO:0001895 12 7 0,000 0,01234241 0,04102384 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01234241 0,0409681 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01234241 0,04091251 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01234241 0,04085707 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01241814 0,04105213 ! regulation of protein localization GO:0032880 188 97 1,000 0,01292009 0,04265374 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,01317434 0,04343443 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,01368938 0,04507164 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 1,000 0,01368938 0,04501098 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01409333 0,0462769 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01409333 0,04621479 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01409333 0,04615284 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01409333 0,04609105 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01409333 0,04602943 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01409333 0,04596798 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01409333 0,04590669 ! male meiosis GO:0007140 9 8 0,000 0,01409333 0,04584556 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01409333 0,0457846 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01409333 0,04572379 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01409333 0,04566315 ! meiotic prophase I GO:0007128 14 8 0,000 0,01409333 0,04560267 ! response to zinc ion GO:0010043 12 8 0,000 0,01409333 0,04554235 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01409333 0,04548219 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01409333 0,04542218 ! oligopeptide transport GO:0006857 16 8 0,000 0,01409333 0,04536234 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01409333 0,04530265 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01409333 0,04524312 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01409333 0,04518375 ! signal peptide processing GO:0006465 12 8 0,000 0,01409333 0,04512453 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01409333 0,04506547 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01409333 0,04500656 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01409333 0,0449478 ! succinate metabolic process GO:0006105 17 8 0,000 0,01409333 0,0448892 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01409333 0,04483075 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01409333 0,04477245 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01409333 0,04471431 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01409333 0,04465631 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01409333 0,04459847 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01409333 0,04454077 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01409333 0,04448322 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01409333 0,04442583 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01409333 0,04436858 ! reflex GO:0060004 17 8 0,000 0,01409333 0,04431147 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01409333 0,04425452 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01409333 0,04419771 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01409333 0,04414105 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01409333 0,04408453 ! pigment granule organization GO:0048753 17 8 0,000 0,01409333 0,04402815 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01409333 0,04397192 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01409333 0,04391584 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01409333 0,04385989 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01409333 0,04380409 ! histidine catabolic process GO:0006548 10 8 0,000 0,01409333 0,04374843 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01409333 0,04369291 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01409333 0,04363754 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01409333 0,0435823 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01409333 0,0435272 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01409333 0,04347224 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01409333 0,04341742 ! melanin metabolic process GO:0006582 17 8 0,000 0,01409333 0,04336274 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01409333 0,0433082 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01409333 0,04325379 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01409333 0,04319952 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01409333 0,04314538 ! macrophage activation GO:0042116 13 8 0,000 0,01409333 0,04309138 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01409333 0,04303752 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01409333 0,04298379 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01409333 0,04293019 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01409333 0,04287673 ! purine salvage GO:0043101 12 8 0,000 0,01409333 0,0428234 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01409333 0,04277021 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01409333 0,04271714 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01409333 0,04266421 ! osteoblast development GO:0002076 17 8 0,000 0,01409333 0,04261141 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01409333 0,04255873 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01409333 0,04250619 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01409333 0,04245378 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01409333 0,0424015 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01409333 0,04234934 ! response to UV-B GO:0010224 17 8 0,000 0,01409333 0,04229732 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01409333 0,04224542 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01409333 0,04219365 ! intermediate filament organization GO:0045109 12 8 0,000 0,01409333 0,042142 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01409333 0,04209048 ! cellular extravasation GO:0045123 13 8 0,000 0,01409333 0,04203909 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01409333 0,04198782 ! response to antibiotic GO:0046677 11 8 0,000 0,01409333 0,04193668 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01409333 0,04188566 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01409333 0,04183477 ! DNA topological change GO:0006265 12 8 0,000 0,01409333 0,041784 ! response to tropane GO:0014073 15 8 0,000 0,01409333 0,04173335 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01409333 0,04168283 ! melanosome transport GO:0032402 13 8 0,000 0,01409333 0,04163243 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01409333 0,04158214 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01409333 0,04153199 ! mast cell activation GO:0045576 14 8 0,000 0,01409333 0,04148195 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01409333 0,04143203 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01409333 0,04138223 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01409333 0,04133255 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01409333 0,04128299 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01409333 0,04123355 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01409333 0,04118423 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01409333 0,04113503 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01409333 0,04108594 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01409333 0,04103697 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01409333 0,04098811 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01409333 0,04093938 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01409333 0,04089076 ! response to tumor cell GO:0002347 16 8 0,000 0,01409333 0,04084225 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01409333 0,04079386 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01409333 0,04074558 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01409333 0,04069742 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01409333 0,04064937 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01409333 0,04060143 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01409333 0,04055361 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01409333 0,0405059 ! hormone catabolic process GO:0042447 17 8 0,000 0,01409333 0,0404583 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01409333 0,04041082 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01409333 0,04036344 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01409333 0,04031618 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01409333 0,04026902 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01409333 0,04022198 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01409333 0,04017505 ! adult feeding behavior GO:0008343 10 8 0,000 0,01409333 0,04012822 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01409333 0,04008151 ! ATP catabolic process GO:0006200 11 8 0,000 0,01409333 0,0400349 ! blastocyst growth GO:0001832 19 8 0,000 0,01409333 0,0399884 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01409333 0,03994201 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01409333 0,03989573 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01409333 0,03984956 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01409333 0,03980349 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01409333 0,03975752 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01409333 0,03971167 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01409333 0,03966592 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01409333 0,03962027 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01409333 0,03957473 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01409333 0,0395293 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01409333 0,03948396 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01409333 0,03943874 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01409333 0,03939361 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01409333 0,03934859 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01409333 0,03930367 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01409333 0,03925886 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01409333 0,03921414 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01409333 0,03916953 ! axon extension GO:0048675 16 9 0,000 0,0158412 0,04397733 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0158412 0,04392741 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0158412 0,04387761 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0158412 0,04382792 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0158412 0,04377834 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0158412 0,04372887 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0158412 0,04367951 ! reproductive behavior GO:0019098 22 9 0,000 0,0158412 0,04363027 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0158412 0,04358114 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,0158412 0,04353211 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0158412 0,0434832 ! UTP metabolic process GO:0046051 10 9 0,000 0,0158412 0,0434344 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0158412 0,04338571 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,0158412 0,04333712 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0158412 0,04328865 ! artery development GO:0060840 25 9 0,000 0,0158412 0,04324028 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0158412 0,04319202 ! regulation of glycolysis GO:0006110 20 9 0,000 0,0158412 0,04314387 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0158412 0,04309582 ! equilibrioception GO:0050957 20 9 0,000 0,0158412 0,04304789 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0158412 0,04300005 ! chemosensory behavior GO:0007635 21 9 0,000 0,0158412 0,04295233 ! microtubule bundle formation GO:0001578 22 9 0,000 0,0158412 0,04290471 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0158412 0,0428572 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,0158412 0,04280979 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0158412 0,04276249 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0158412 0,04271529 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0158412 0,04266819 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0158412 0,0426212 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0158412 0,04257431 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0158412 0,04252753 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0158412 0,04248084 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0158412 0,04243426 ! protein targeting to ER GO:0045047 25 9 0,000 0,0158412 0,04238779 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0158412 0,04234141 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0158412 0,04229514 ! T cell selection GO:0045058 27 9 0,000 0,0158412 0,04224896 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0158412 0,04220289 ! glycine catabolic process GO:0006546 15 9 0,000 0,0158412 0,04215692 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0158412 0,04211104 ! endosome organization GO:0007032 20 9 0,000 0,0158412 0,04206527 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0158412 0,0420196 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0158412 0,04197402 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0158412 0,04192855 ! mannose metabolic process GO:0006013 13 9 0,000 0,0158412 0,04188317 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0158412 0,04183789 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0158412 0,04179271 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0158412 0,04174763 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0158412 0,04170264 ! receptor clustering GO:0043113 20 9 0,000 0,0158412 0,04165775 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0158412 0,04161296 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0158412 0,04156826 ! retinol metabolic process GO:0042572 20 9 0,000 0,0158412 0,04152366 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0158412 0,04147915 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0158412 0,04143474 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0158412 0,04139043 ! macrophage differentiation GO:0030225 15 9 0,000 0,0158412 0,04134621 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0158412 0,04130208 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0158412 0,04125805 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0158412 0,04121411 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0158412 0,04117027 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0158412 0,04112651 ! response to amine stimulus GO:0014075 13 9 0,000 0,0158412 0,04108286 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0158412 0,04103929 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0158412 0,04099582 ! erythrocyte development GO:0048821 17 9 0,000 0,0158412 0,04095243 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0158412 0,04090914 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,0158412 0,04086594 ! renal water homeostasis GO:0003091 15 9 0,000 0,0158412 0,04082284 ! postreplication repair GO:0006301 25 9 0,000 0,0158412 0,04077982 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0158412 0,04073689 ! icosanoid secretion GO:0032309 15 9 0,000 0,0158412 0,04069406 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0158412 0,04065131 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0158412 0,04060866 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0158412 0,04056609 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0158412 0,04052361 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0158412 0,04048122 ! sterol catabolic process GO:0016127 14 9 0,000 0,0158412 0,04043892 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0158412 0,04039671 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0158412 0,04035459 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0158412 0,04031255 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,0158412 0,0402706 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,0158412 0,04022874 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0158412 0,04018697 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,0158412 0,04014528 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0158412 0,04010368 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0158412 0,04006216 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0158412 0,04002073 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0158412 0,03997939 ! purine base metabolic process GO:0006144 25 9 0,000 0,0158412 0,03993813 ! pigment granule transport GO:0051904 17 9 0,000 0,0158412 0,03989696 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,0158412 0,03985587 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0158412 0,03981487 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0158412 0,03977395 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0158412 0,03973311 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0158412 0,03969236 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0158412 0,03965169 ! mitochondrion localization GO:0051646 18 9 0,000 0,0158412 0,0396111 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01758601 0,04392907 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01758601 0,0438842 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01758601 0,04383942 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01758601 0,04379473 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01758601 0,04375014 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01758601 0,04370563 ! associative learning GO:0008306 21 10 0,000 0,01758601 0,04366121 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01758601 0,04361689 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01758601 0,04357265 ! phosphate transport GO:0006817 24 10 0,000 0,01758601 0,0435285 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01758601 0,04348445 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01758601 0,04344048 ! CTP metabolic process GO:0046036 11 10 0,000 0,01758601 0,0433966 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01758601 0,04335281 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01758601 0,04330911 ! GTP metabolic process GO:0046039 11 10 0,000 0,01758601 0,04326549 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01758601 0,04322196 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01758601 0,04317853 ! social behavior GO:0035176 29 10 0,000 0,01758601 0,04313517 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01758601 0,04309191 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01758601 0,04304873 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01758601 0,04300564 ! androgen metabolic process GO:0008209 17 10 0,000 0,01758601 0,04296263 ! phospholipid efflux GO:0033700 19 10 0,000 0,01758601 0,04291971 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01758601 0,04287688 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01758601 0,04283413 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01758601 0,04279147 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01758601 0,04274889 ! lung alveolus development GO:0048286 26 10 0,000 0,01758601 0,04270639 ! pathogenesis GO:0009405 17 10 0,000 0,01758601 0,04266398 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01758601 0,04262166 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01758601 0,04257942 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01758601 0,04253726 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01758601 0,04249519 ! endoderm development GO:0007492 18 10 0,000 0,01758601 0,04245319 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01758601 0,04241129 ! arginine catabolic process GO:0006527 17 10 0,000 0,01758601 0,04236946 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01758601 0,04232772 ! proline metabolic process GO:0006560 13 10 0,000 0,01758601 0,04228606 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01758601 0,04224448 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01758601 0,04220298 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01758601 0,04216156 ! V(D)J recombination GO:0033151 34 10 0,000 0,01758601 0,04212023 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01758601 0,04207897 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01758601 0,0420378 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01758601 0,04199671 ! B cell proliferation GO:0042100 19 10 0,000 0,01758601 0,0419557 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01758601 0,04191476 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01758601 0,04187391 ! multicellular organism growth GO:0035264 19 10 0,000 0,01758601 0,04183314 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01758601 0,04179244 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01758601 0,04175183 ! ruffle organization GO:0031529 17 10 0,000 0,01758601 0,04171129 ! epithelial cell development GO:0002064 21 10 0,000 0,01758601 0,04167084 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01758601 0,04163046 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01758601 0,04159016 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01758601 0,04154993 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01758601 0,04150979 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01758601 0,04146972 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01758601 0,04142973 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01758601 0,04138982 ! motor axon guidance GO:0008045 22 10 0,000 0,01758601 0,04134998 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01758601 0,04131022 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01758601 0,04127054 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01758601 0,04123093 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01758601 0,0411914 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01758601 0,04115195 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01758601 0,04111257 ! segment specification GO:0007379 15 10 0,000 0,01758601 0,04107326 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01758601 0,04103403 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01758601 0,04099488 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01758601 0,0409558 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01758601 0,04091679 ! response to dsRNA GO:0043331 23 10 0,000 0,01758601 0,04087786 ! DNA ligation GO:0006266 18 10 0,000 0,01758601 0,040839 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01758601 0,04080022 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01758601 0,04076151 ! melanosome localization GO:0032400 16 10 0,000 0,01758601 0,04072287 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01758601 0,04068431 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01758601 0,04064582 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01758601 0,0406074 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01758601 0,04056906 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01758601 0,04053079 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01758601 0,04049259 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01758601 0,04045446 ! protein sumoylation GO:0016925 17 10 0,000 0,01758601 0,0404164 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01758601 0,04037841 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01758601 0,0403405 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01758601 0,04030266 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01758601 0,04026489 ! salivary gland development GO:0007431 28 10 0,000 0,01758601 0,04022718 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01758601 0,04018955 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01758601 0,04015199 ! midbrain development GO:0030901 14 10 0,000 0,01758601 0,0401145 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01758601 0,04007708 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01758601 0,04003973 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01758601 0,04000245 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01758601 0,03996524 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01758601 0,0399281 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01758601 0,03989102 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01758601 0,03985402 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01758601 0,03981708 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01758601 0,03978022 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01758601 0,03974342 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01758601 0,03970668 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01758601 0,03967002 ! blastocyst formation GO:0001825 18 10 0,000 0,01758601 0,03963343 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01758601 0,0395969 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01758601 0,03956044 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01758601 0,03952404 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01758601 0,03948771 ! response to nicotine GO:0035094 20 10 0,000 0,01758601 0,03945145 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01758601 0,03941526 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01758601 0,03937913 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01932778 0,04323972 ! respiratory burst GO:0045730 17 11 0,000 0,01932778 0,04320016 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01932778 0,04316068 ! neuron fate specification GO:0048665 18 11 0,000 0,01932778 0,04312126 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01932778 0,04308191 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01932778 0,04304264 ! thyroid gland development GO:0030878 26 11 0,000 0,01932778 0,04300344 ! synapsis GO:0007129 14 11 0,000 0,01932778 0,04296431 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01932778 0,04292525 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01932778 0,04288627 ! response to pain GO:0048265 27 11 0,000 0,01932778 0,04284735 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01932778 0,0428085 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01932778 0,04276973 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01932778 0,04273102 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01932778 0,04269239 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01932778 0,04265382 ! bone resorption GO:0045453 16 11 0,000 0,01932778 0,04261532 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01932778 0,0425769 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01932778 0,04253854 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01932778 0,04250025 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01932778 0,04246203 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01932778 0,04242388 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01932778 0,0423858 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01932778 0,04234778 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01932778 0,04230984 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01932778 0,04227196 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01932778 0,04223415 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01932778 0,04219641 ! UV protection GO:0009650 20 11 0,000 0,01932778 0,04215873 ! adult heart development GO:0007512 16 11 0,000 0,01932778 0,04212112 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01932778 0,04208358 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01932778 0,04204611 ! macroautophagy GO:0016236 19 11 0,000 0,01932778 0,0420087 ! temperature homeostasis GO:0001659 18 11 0,000 0,01932778 0,04197136 ! behavioral fear response GO:0001662 27 11 0,000 0,01932778 0,04193408 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01932778 0,04189688 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01932778 0,04185973 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01932778 0,04182266 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01932778 0,04178564 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01932778 0,0417487 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01932778 0,04171182 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01932778 0,041675 ! regulation of organ growth GO:0046620 14 11 0,000 0,01932778 0,04163825 ! pigment granule localization GO:0051875 20 11 0,000 0,01932778 0,04160157 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01932778 0,04156495 ! vasoconstriction GO:0042310 20 11 0,000 0,01932778 0,04152839 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01932778 0,0414919 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01932778 0,04145547 ! embryonic axis specification GO:0000578 19 11 0,000 0,01932778 0,0414191 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01932778 0,0413828 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01932778 0,04134657 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01932778 0,04131039 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01932778 0,04127428 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01932778 0,04123823 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01932778 0,04120225 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01932778 0,04116633 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01932778 0,04113047 ! prophase GO:0051324 17 11 0,000 0,01932778 0,04109467 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01932778 0,04105894 ! nucleosome positioning GO:0016584 15 11 0,000 0,01932778 0,04102327 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01932778 0,04098766 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01932778 0,04095211 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01932778 0,04091662 ! apical protein localization GO:0045176 18 11 0,000 0,01932778 0,04088119 ! acid secretion GO:0046717 20 11 0,000 0,01932778 0,04084583 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01932778 0,04081053 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01932778 0,04077528 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01932778 0,0407401 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01932778 0,04070498 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01932778 0,04066992 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01932778 0,04063492 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01932778 0,04059998 ! cholesterol efflux GO:0033344 21 11 0,000 0,01932778 0,0405651 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01932778 0,04053028 ! oocyte development GO:0048599 20 11 0,000 0,01932778 0,04049552 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01932778 0,04046082 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01932778 0,04042618 ! embryonic gut development GO:0048566 19 11 0,000 0,01932778 0,0403916 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01932778 0,04035708 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01932778 0,04032261 ! activation of innate immune response GO:0002218 16 11 0,000 0,01932778 0,04028821 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01932778 0,04025386 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01932778 0,04021957 ! lysogeny GO:0030069 22 11 0,000 0,01932778 0,04018534 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01932778 0,04015117 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01932778 0,04011706 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01932778 0,040083 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01932778 0,04004901 ! nucleus localization GO:0051647 22 11 0,000 0,01932778 0,04001507 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02106652 0,0435779 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02106652 0,04354103 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02106652 0,04350423 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02106652 0,04346748 ! virus-host interaction GO:0019048 30 12 0,000 0,02106652 0,0434308 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02106652 0,04339418 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02106652 0,04335762 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02106652 0,04332113 ! protein complex disassembly GO:0043241 28 12 0,000 0,02106652 0,04328469 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02106652 0,04324832 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02106652 0,04321201 ! hippocampus development GO:0021766 29 12 0,000 0,02106652 0,04317575 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02106652 0,04313956 ! T cell proliferation GO:0042098 32 12 0,000 0,02106652 0,04310343 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02106652 0,04306736 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02106652 0,04303135 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02106652 0,04299541 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02106652 0,04295952 ! drug transport GO:0015893 16 12 0,000 0,02106652 0,04292369 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02106652 0,04288792 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02106652 0,04285221 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02106652 0,04281656 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02106652 0,04278096 ! focal adhesion formation GO:0048041 37 12 0,000 0,02106652 0,04274543 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02106652 0,04270996 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02106652 0,04267454 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02106652 0,04263919 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02106652 0,04260389 ! lipid digestion GO:0044241 21 12 0,000 0,02106652 0,04256865 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02106652 0,04253347 ! entry into host cell GO:0030260 34 12 0,000 0,02106652 0,04249835 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02106652 0,04246328 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02106652 0,04242828 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02106652 0,04239333 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02106652 0,04235844 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02106652 0,0423236 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02106652 0,04228882 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02106652 0,0422541 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02106652 0,04221944 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02106652 0,04218484 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02106652 0,04215029 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02106652 0,04211579 ! cranial nerve development GO:0021545 23 12 0,000 0,02106652 0,04208136 ! fucose catabolic process GO:0019317 25 12 0,000 0,02106652 0,04204698 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02106652 0,04201265 ! histone acetylation GO:0016573 27 12 0,000 0,02106652 0,04197838 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02106652 0,04194417 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02106652 0,04191002 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02106652 0,04187592 ! zymogen activation GO:0031638 18 12 0,000 0,02106652 0,04184187 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02106652 0,04180788 ! T cell homeostasis GO:0043029 28 12 0,000 0,02106652 0,04177394 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02106652 0,04174006 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02106652 0,04170624 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02106652 0,04167247 ! oocyte differentiation GO:0009994 21 12 0,000 0,02106652 0,04163875 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02106652 0,04160509 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02106652 0,04157149 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02106652 0,04153793 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02106652 0,04150444 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02106652 0,04147099 ! defense response to fungus GO:0050832 15 12 0,000 0,02106652 0,0414376 ! embryonic placenta development GO:0001892 21 12 0,000 0,02106652 0,04140426 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02106652 0,04137098 ! response to cold GO:0009409 17 12 0,000 0,02106652 0,04133775 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02106652 0,04130457 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02106652 0,04127145 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02280221 0,04463607 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02280221 0,04460033 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02280221 0,04456465 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02280221 0,04452902 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02280221 0,04449346 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02280221 0,04445795 ! peroxisomal transport GO:0043574 28 13 0,000 0,02280221 0,0444225 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02280221 0,0443871 ! cartilage condensation GO:0001502 22 13 0,000 0,02280221 0,04435176 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02280221 0,04431648 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02280221 0,04428125 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02280221 0,04424608 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02280221 0,04421096 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02280221 0,0441759 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02280221 0,04414089 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02280221 0,04410595 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02280221 0,04407105 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02280221 0,04403621 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02280221 0,04400143 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02280221 0,0439667 ! methionine metabolic process GO:0006555 31 13 0,000 0,02280221 0,04393203 ! plasma membrane organization GO:0007009 27 13 0,000 0,02280221 0,04389741 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02280221 0,04386284 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02280221 0,04382833 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02280221 0,04379388 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02280221 0,04375947 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02280221 0,04372513 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02280221 0,04369083 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02280221 0,04365659 ! exocrine system development GO:0035272 34 13 0,000 0,02280221 0,0436224 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02280221 0,04358827 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02280221 0,04355419 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02280221 0,04352016 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02280221 0,04348619 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02280221 0,04345227 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02280221 0,0434184 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02280221 0,04338459 ! protein homotetramerization GO:0051289 24 13 0,000 0,02280221 0,04335082 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02280221 0,04331711 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02280221 0,04328346 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02280221 0,04324985 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02280221 0,0432163 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02280221 0,0431828 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02280221 0,04314935 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02280221 0,04311595 ! histone methylation GO:0016571 29 13 0,000 0,02280221 0,04308261 ! chromatin silencing GO:0006342 29 13 0,000 0,02280221 0,04304931 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02280221 0,04301607 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02280221 0,04298288 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02280221 0,04294974 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02280221 0,04291665 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02280221 0,04288361 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02280221 0,04285062 ! spleen development GO:0048536 24 13 0,000 0,02280221 0,04281769 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02280221 0,0427848 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02280221 0,04275196 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02280221 0,04271918 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02280221 0,04268644 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02280221 0,04265376 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02280221 0,04262112 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02280221 0,04258854 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02280221 0,042556 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02280221 0,04252352 ! insulin secretion GO:0030073 24 13 0,000 0,02280221 0,04249108 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02280221 0,0424587 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02280221 0,04242636 ! acrosome reaction GO:0007340 19 13 0,000 0,02280221 0,04239407 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02280221 0,04236183 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02280221 0,04232964 ! rRNA transcription GO:0009303 28 14 0,000 0,02453488 0,04551156 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02453488 0,04547703 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02453488 0,04544255 ! water transport GO:0006833 21 14 0,000 0,02453488 0,04540812 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02453488 0,04537375 ! non-recombinational repair GO:0000726 29 14 0,000 0,02453488 0,04533942 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02453488 0,04530515 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02453488 0,04527094 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02453488 0,04523677 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02453488 0,04520265 ! palate development GO:0060021 32 14 0,000 0,02453488 0,04516859 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02453488 0,04513458 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02453488 0,04510062 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02453488 0,04506671 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02453488 0,04503285 ! arginine metabolic process GO:0006525 21 14 0,000 0,02453488 0,04499904 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02453488 0,04496528 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02453488 0,04493157 ! regulation of heart rate GO:0002027 25 14 0,000 0,02453488 0,04489792 ! fear response GO:0042596 34 14 0,000 0,02453488 0,04486431 ! organic alcohol transport GO:0015850 29 14 0,000 0,02453488 0,04483076 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02453488 0,04479725 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02453488 0,04476379 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02453488 0,04473039 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02453488 0,04469703 ! bone mineralization GO:0030282 18 14 0,000 0,02453488 0,04466373 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02453488 0,04463047 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02453488 0,04459726 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02453488 0,0445641 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02453488 0,044531 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02453488 0,04449794 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02453488 0,04446493 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02453488 0,04443196 ! ribosome assembly GO:0042255 18 14 0,000 0,02453488 0,04439905 ! cerebellum development GO:0021549 23 14 0,000 0,02453488 0,04436619 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02453488 0,04433337 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02453488 0,04430061 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02453488 0,04426789 ! response to gamma radiation GO:0010332 30 14 0,000 0,02453488 0,04423522 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02453488 0,0442026 ! NADP metabolic process GO:0006739 24 14 0,000 0,02453488 0,04417002 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02453488 0,0441375 ! oxygen transport GO:0015671 22 14 0,000 0,02453488 0,04410502 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02453488 0,04407259 ! male genitalia development GO:0030539 26 14 0,000 0,02453488 0,04404021 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02453488 0,04400787 ! regulation of axon extension GO:0030516 43 14 0,000 0,02453488 0,04397558 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02453488 0,04394334 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02453488 0,04391115 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02626453 0,04697236 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02626453 0,046938 ! reproductive cellular process GO:0048610 22 15 0,000 0,02626453 0,04690369 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02626453 0,04686943 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02626453 0,04683521 ! superoxide anion generation GO:0042554 22 15 0,000 0,02626453 0,04680105 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02626453 0,04676694 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02626453 0,04673288 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02626453 0,04669887 ! copper ion transport GO:0006825 22 15 0,000 0,02626453 0,0466649 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02626453 0,04663099 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02626453 0,04659713 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02626453 0,04656331 ! sulfate transport GO:0008272 27 15 0,000 0,02626453 0,04652955 ! response to cAMP GO:0051591 25 15 0,000 0,02626453 0,04649583 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02626453 0,04646216 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02626453 0,04642854 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02626453 0,04639497 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02626453 0,04636145 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02626453 0,04632797 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02626453 0,04629455 ! vesicle coating GO:0006901 38 15 0,000 0,02626453 0,04626117 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02626453 0,04622784 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02626453 0,04619456 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02626453 0,04616133 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02626453 0,04612814 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02626453 0,046095 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02626453 0,04606191 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02626453 0,04602887 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02626453 0,04599587 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02626453 0,04596293 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02626453 0,04593002 ! histone deacetylation GO:0016575 24 15 0,000 0,02626453 0,04589717 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02626453 0,04586436 ! water homeostasis GO:0030104 28 15 0,000 0,02626453 0,0458316 ! cofactor transport GO:0051181 30 15 0,000 0,02626453 0,04579889 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02626453 0,04576622 ! muscle maintenance GO:0046716 26 15 0,000 0,02626453 0,0457336 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02626453 0,04570103 ! intestinal absorption GO:0050892 31 15 0,000 0,02626453 0,0456685 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02626453 0,04563602 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02626453 0,04560358 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02626453 0,0455712 ! cell killing GO:0001906 32 15 0,000 0,02626453 0,04553885 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02626453 0,04550656 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02626453 0,0454743 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02626453 0,0454421 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02626453 0,04540994 ! actin filament polymerization GO:0030041 27 15 0,000 0,02626453 0,04537782 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02626453 0,04534575 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02799116 0,04829265 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02799116 0,04825857 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02799116 0,04822454 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02799116 0,04819055 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02799116 0,04815662 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02799116 0,04812273 ! bone remodeling GO:0046849 28 16 0,000 0,02799116 0,04808888 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02799116 0,04805509 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02799116 0,04802134 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02799116 0,04798764 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02799116 0,04795399 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02799116 0,04792039 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02799116 0,04788683 ! startle response GO:0001964 28 16 0,000 0,02799116 0,04785332 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02799116 0,04781986 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02799116 0,04778644 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02799116 0,04775307 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02799116 0,04771974 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02799116 0,04768647 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02799116 0,04765324 ! pituitary gland development GO:0021983 30 16 0,000 0,02799116 0,04762005 ! response to osmotic stress GO:0006970 27 16 0,000 0,02799116 0,04758691 ! lysosomal transport GO:0007041 31 16 0,000 0,02799116 0,04755382 ! fructose metabolic process GO:0006000 25 16 0,000 0,02799116 0,04752077 ! L-amino acid transport GO:0015807 33 16 0,000 0,02799116 0,04748777 ! stem cell development GO:0048864 46 16 0,000 0,02799116 0,04745482 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02799116 0,04742191 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02799116 0,04738905 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02799116 0,04735623 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02799116 0,04732346 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02799116 0,04729073 ! axon cargo transport GO:0008088 46 16 0,000 0,02799116 0,04725805 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02799116 0,04722541 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02799116 0,04719282 ! DNA replication initiation GO:0006270 28 16 0,000 0,02799116 0,04716027 ! neuron recognition GO:0008038 40 16 0,000 0,02799116 0,04712777 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02799116 0,04709531 ! tissue regeneration GO:0042246 27 16 0,000 0,02799116 0,0470629 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02799116 0,04703053 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02799116 0,04699821 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02799116 0,04696593 ! biomineral formation GO:0031214 22 16 0,000 0,02799116 0,04693369 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02799116 0,0469015 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02799116 0,04686936 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02799116 0,04683726 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02799116 0,0468052 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02799116 0,04677318 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02799116 0,04674121 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02799116 0,04670929 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02799116 0,0466774 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02799116 0,04664556 ! peptide hormone processing GO:0016486 27 16 0,000 0,02799116 0,04661377 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02971477 0,0494504 ! metencephalon development GO:0022037 32 17 0,000 0,02971477 0,04941673 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02971477 0,04938312 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02971477 0,04934955 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02971477 0,04931602 ! signal complex assembly GO:0007172 47 17 0,000 0,02971477 0,04928254 ! filopodium assembly GO:0046847 42 17 0,000 0,02971477 0,04924911 ! endothelial cell migration GO:0043542 31 17 0,000 0,02971477 0,04921572 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02971477 0,04918237 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02971477 0,04914907 ! glial cell development GO:0021782 28 17 0,000 0,02971477 0,04911582 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02971477 0,04908261 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02971477 0,04904945 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02971477 0,04901633 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02971477 0,04898325 ! myoblast differentiation GO:0045445 50 17 0,000 0,02971477 0,04895022 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02971477 0,04891724 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02971477 0,0488843 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02971477 0,0488514 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02971477 0,04881855 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02971477 0,04878574 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02971477 0,04875298 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02971477 0,04872026 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02971477 0,04868758 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02971477 0,04865495 ! membrane budding GO:0006900 42 17 0,000 0,02971477 0,04862236 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02971477 0,04858981 ! regulation of protein binding GO:0043393 33 17 0,000 0,02971477 0,04855731 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02971477 0,04852485 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02971477 0,04849244 ! genitalia development GO:0048806 32 17 0,000 0,02971477 0,04846007 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02971477 0,04842774 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02971477 0,04839545 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02971477 0,04836321 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02971477 0,04833101 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02971477 0,04829886 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02971477 0,04826674 ! steroid catabolic process GO:0006706 34 17 0,000 0,02971477 0,04823467 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02971477 0,04820264 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02971477 0,04817066 ! gas transport GO:0015669 26 17 0,000 0,02971477 0,04813872 ! organic cation transport GO:0015695 32 17 0,000 0,02971477 0,04810681 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02971477 0,04807496 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02971477 0,04804314 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02971477 0,04801136 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03143538 0,05075785 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03143538 0,05072432 ! limbic system development GO:0021761 40 18 0,000 0,03143538 0,05069084 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03143538 0,0506574 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03143538 0,05062401 ! adult walking behavior GO:0007628 36 18 0,000 0,03143538 0,05059066 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03143538 0,05055736 ! heart looping GO:0001947 34 18 0,000 0,03143538 0,05052409 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03143538 0,05049088 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03143538 0,0504577 ! centrosome cycle GO:0007098 26 18 0,000 0,03143538 0,05042457 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03143538 0,05039148 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03143538 0,05035844 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03143538 0,05032544 ! glycine metabolic process GO:0006544 30 18 0,000 0,03143538 0,05029248 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03143538 0,05025957 ! response to retinoic acid GO:0032526 31 18 0,000 0,03143538 0,0502267 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03143538 0,05019387 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03143538 0,05016109 ! DNA integration GO:0015074 32 18 0,000 0,03143538 0,05012834 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03143538 0,05009564 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03143538 0,05006299 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03143538 0,05003037 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03143538 0,0499978 ! neural crest cell migration GO:0001755 41 18 0,000 0,03143538 0,04996527 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03143538 0,04993278 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03143538 0,04990034 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03143538 0,04986794 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03143538 0,04983558 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03143538 0,04980326 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03143538 0,04977098 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03143538 0,04973875 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03143538 0,04970655 ! detection of bacterium GO:0016045 22 18 0,000 0,03143538 0,0496744 ! nerve development GO:0021675 34 18 0,000 0,03143538 0,04964229 ! defense response to virus GO:0051607 43 18 0,000 0,03143538 0,04961022 ! microspike assembly GO:0030035 46 18 0,000 0,03143538 0,04957819 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03143538 0,04954621 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03143538 0,04951426 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03315298 0,05218604 ! positive regulation of translation GO:0045727 31 19 0,000 0,03315298 0,05215243 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03315298 0,05211887 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03315298 0,05208536 ! neuron maturation GO:0042551 46 19 0,000 0,03315298 0,05205188 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03315298 0,05201845 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03315298 0,05198506 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03315298 0,05195172 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03315298 0,05191841 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03315298 0,05188516 ! inositol metabolic process GO:0006020 33 19 0,000 0,03315298 0,05185194 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03315298 0,05181876 ! memory GO:0007613 34 19 0,000 0,03315298 0,05178563 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03315298 0,05175254 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03315298 0,05171949 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03315298 0,05168649 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03315298 0,05165353 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03315298 0,0516206 ! cerebral cortex development GO:0021987 40 19 0,000 0,03315298 0,05158772 ! pigmentation during development GO:0048066 42 19 0,000 0,03315298 0,05155489 ! response to vitamin A GO:0033189 32 19 0,000 0,03315298 0,05152209 ! heme metabolic process GO:0042168 40 19 0,000 0,03315298 0,05148934 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03315298 0,05145662 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03315298 0,05142395 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03315298 0,05139132 ! response to fungus GO:0009620 26 19 0,000 0,03315298 0,05135874 ! peptide cross-linking GO:0018149 39 19 0,000 0,03315298 0,05132619 ! protein export from nucleus GO:0006611 40 19 0,000 0,03315298 0,05129368 ! heart process GO:0003015 32 19 0,000 0,03315298 0,05126122 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03315298 0,0512288 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03315298 0,05119641 ! visual learning GO:0008542 38 19 0,000 0,03315298 0,05116407 ! cellular pigmentation GO:0033059 37 19 0,000 0,03315298 0,05113177 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03315298 0,05109951 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03315298 0,05106729 ! vitamin transport GO:0051180 31 19 0,000 0,03315298 0,05103511 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03315298 0,05100298 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03315298 0,05097088 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03315298 0,05093882 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03315298 0,05090681 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03315298 0,05087483 ! cilium assembly GO:0042384 38 19 0,000 0,03315298 0,05084289 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03315298 0,050811 ! protein secretion GO:0009306 45 20 0,000 0,03486758 0,05340533 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03486758 0,05337187 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03486758 0,05333845 ! positive regulation of ossification GO:0045778 50 20 0,000 0,03486758 0,05330507 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03486758 0,05327174 ! skin development GO:0043588 42 20 0,000 0,03486758 0,05323844 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03486758 0,05320519 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03486758 0,05317198 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,03486758 0,05313881 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03486758 0,05310568 ! response to vitamin GO:0033273 36 20 0,000 0,03486758 0,05307259 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03486758 0,05303954 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,03486758 0,05300654 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03486758 0,05297358 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03486758 0,05294065 ! response to alkaloid GO:0043279 38 20 0,000 0,03486758 0,05290777 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03486758 0,05287493 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,03486758 0,05284213 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,03486758 0,05280937 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03486758 0,05277665 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03486758 0,05274397 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03486758 0,05271133 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,03486758 0,05267873 ! actin filament bundle formation GO:0051017 47 20 0,000 0,03486758 0,05264617 ! body fluid secretion GO:0007589 33 20 0,000 0,03486758 0,05261366 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03486758 0,05258118 ! peptide secretion GO:0002790 38 20 0,000 0,03486758 0,05254874 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03486758 0,05251634 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03486758 0,05248399 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03486758 0,05245167 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03486758 0,05241939 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03486758 0,05238715 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03486758 0,05235495 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03486758 0,05232279 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03486758 0,05229067 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,03486758 0,05225859 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03486758 0,05222655 ! regulation of glucose import GO:0046324 30 20 0,000 0,03486758 0,05219455 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03486758 0,05216259 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03486758 0,05213067 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03486758 0,05209878 ! negative regulation of translation GO:0017148 32 20 0,000 0,03486758 0,05206694 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03486758 0,05203513 ! regulation of cell killing GO:0031341 46 21 0,000 0,0365792 0,05455615 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,0365792 0,05452287 ! hormone secretion GO:0046879 39 21 0,000 0,0365792 0,05448962 ! cAMP metabolic process GO:0046058 41 21 0,000 0,0365792 0,05445642 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,0365792 0,05442325 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,0365792 0,05439013 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,0365792 0,05435704 ! ovarian follicle development GO:0001541 39 21 0,000 0,0365792 0,054324 ! smooth muscle contraction GO:0006939 48 21 0,000 0,0365792 0,054291 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,0365792 0,05425803 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,0365792 0,05422511 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,0365792 0,05419223 ! plasma membrane fusion GO:0045026 33 21 0,000 0,0365792 0,05415938 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,0365792 0,05412658 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,0365792 0,05409381 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,0365792 0,05406109 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,0365792 0,0540284 ! diencephalon development GO:0021536 36 21 0,000 0,0365792 0,05399576 ! collagen fibril organization GO:0030199 62 21 0,000 0,0365792 0,05396315 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,0365792 0,05393059 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,0365792 0,05389806 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,0365792 0,05386557 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,0365792 0,05383312 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,0365792 0,05380071 ! collagen catabolic process GO:0030574 29 21 0,000 0,0365792 0,05376834 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,0365792 0,05373601 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,0365792 0,05370371 ! sperm-egg recognition GO:0035036 23 21 0,000 0,0365792 0,05367146 ! actin filament-based movement GO:0030048 47 21 0,000 0,0365792 0,05363924 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,0365792 0,05360707 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,03828782 0,05607743 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,03828782 0,05604383 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,03828782 0,05601027 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,03828782 0,05597675 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,03828782 0,05594327 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,03828782 0,05590983 ! microtubule-based transport GO:0010970 59 22 0,000 0,03828782 0,05587643 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,03828782 0,05584308 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,03828782 0,05580976 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,03828782 0,05577648 ! cellular response to starvation GO:0009267 37 22 0,000 0,03828782 0,05574324 ! vacuolar transport GO:0007034 41 22 0,000 0,03828782 0,05571004 ! central nervous system neuron development GO:0021954 47 22 0,000 0,03828782 0,05567688 ! fucose metabolic process GO:0006004 44 22 0,000 0,03828782 0,05564375 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,03828782 0,05561067 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,03828782 0,05557763 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,03828782 0,05554463 ! ureteric bud development GO:0001657 50 22 0,000 0,03828782 0,05551166 ! cell aging GO:0007569 48 22 0,000 0,03828782 0,05547874 ! stem cell differentiation GO:0048863 57 22 0,000 0,03828782 0,05544585 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,03828782 0,055413 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,03828782 0,0553802 ! cytolysis GO:0019835 27 22 0,000 0,03828782 0,05534743 ! renal system process GO:0003014 42 22 0,000 0,03828782 0,0553147 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,03828782 0,055282 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,03828782 0,05524935 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,03828782 0,05521674 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,03828782 0,05518416 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,03828782 0,05515162 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,03828782 0,05511912 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,03828782 0,05508666 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,03828782 0,05505424 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,03828782 0,05502185 ! sarcomere organization GO:0045214 32 22 0,000 0,03828782 0,05498951 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,03828782 0,0549572 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,03828782 0,05492493 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,03828782 0,05489269 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,03828782 0,0548605 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,03828782 0,05482834 ! gut development GO:0048565 44 22 0,000 0,03828782 0,05479622 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,03828782 0,05476414 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,03828782 0,0547321 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,03828782 0,05470009 ! protein stabilization GO:0050821 41 22 0,000 0,03828782 0,05466812 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,03999347 0,05707012 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,03999347 0,0570368 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03999347 0,05700352 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03999347 0,05697029 ! gluconeogenesis GO:0006094 38 23 0,000 0,03999347 0,05693709 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03999347 0,05690392 ! viral genome replication GO:0019079 44 23 0,000 0,03999347 0,0568708 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03999347 0,05683772 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03999347 0,05680467 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03999347 0,05677167 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,03999347 0,0567387 ! regeneration GO:0031099 42 23 0,000 0,03999347 0,05670577 ! axis specification GO:0009798 43 23 0,000 0,03999347 0,05667288 ! visual behavior GO:0007632 46 23 0,000 0,03999347 0,05664002 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,03999347 0,05660721 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,03999347 0,05657443 ! response to ethanol GO:0045471 47 23 0,000 0,03999347 0,05654169 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03999347 0,05650899 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03999347 0,05647632 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03999347 0,0564437 ! peroxisome organization GO:0007031 43 23 0,000 0,03999347 0,05641111 ! lysosome organization GO:0007040 47 23 0,000 0,03999347 0,05637856 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,03999347 0,05634604 ! vesicle targeting GO:0006903 49 23 0,000 0,03999347 0,05631357 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03999347 0,05628113 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03999347 0,05624873 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03999347 0,05621636 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03999347 0,05618404 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,03999347 0,05615175 ! DNA modification GO:0006304 36 23 0,000 0,03999347 0,05611949 ! fatty acid transport GO:0015908 47 23 0,000 0,03999347 0,05608728 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,03999347 0,0560551 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,03999347 0,05602296 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03999347 0,05599085 ! hormone transport GO:0009914 41 23 0,000 0,03999347 0,05595879 ! cell-cell recognition GO:0009988 28 23 0,000 0,03999347 0,05592675 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03999347 0,05589476 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03999347 0,0558628 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03999347 0,05583088 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,04169613 0,05817456 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,04169613 0,05814135 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,04169613 0,05810819 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,04169613 0,05807506 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,04169613 0,05804197 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,04169613 0,05800891 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,04169613 0,0579759 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,04169613 0,05794292 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,04169613 0,05790998 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,04169613 0,05787708 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,04169613 0,05784421 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,04169613 0,05781138 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,04169613 0,05777859 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,04169613 0,05774583 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,04169613 0,05771312 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,04169613 0,05768044 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,04169613 0,05764779 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,04169613 0,05761519 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,04169613 0,05758262 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,04169613 0,05755009 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,04169613 0,05751759 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,04169613 0,05748513 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,04169613 0,05745271 ! pallium development GO:0021543 56 24 0,000 0,04169613 0,05742032 ! oogenesis GO:0048477 44 24 0,000 0,04169613 0,05738797 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,04169613 0,05735566 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,04169613 0,05732338 ! platelet activation GO:0030168 41 24 0,000 0,04169613 0,05729114 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,04169613 0,05725894 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,04169613 0,05722677 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,04169613 0,05719464 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,04169613 0,05716254 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,04169613 0,05713048 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,04169613 0,05709846 ! regulation of amine transport GO:0051952 41 24 0,000 0,04169613 0,05706647 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,04339583 0,05935947 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,04339583 0,05932625 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,04339583 0,05929307 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,04339583 0,05925993 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,04339583 0,05922682 ! leukocyte adhesion GO:0007159 55 25 0,000 0,04339583 0,05919375 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,04339583 0,05916072 ! phototransduction GO:0007602 37 25 0,000 0,04339583 0,05912772 ! keratinization GO:0031424 37 25 0,000 0,04339583 0,05909476 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,04339583 0,05906184 ! vacuole organization GO:0007033 49 25 0,000 0,04339583 0,05902896 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,04339583 0,05899611 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,04339583 0,0589633 ! receptor metabolic process GO:0043112 53 25 0,000 0,04339583 0,05893052 ! chromosome condensation GO:0030261 48 25 0,000 0,04339583 0,05889778 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,04339583 0,05886508 ! regulation of behavior GO:0050795 48 25 0,000 0,04339583 0,05883241 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,04339583 0,05879978 ! interaction with host GO:0051701 66 25 0,000 0,04339583 0,05876719 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,04339583 0,05873463 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,04339583 0,05870211 ! immunoglobulin production GO:0002377 62 25 0,000 0,04339583 0,05866962 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,04339583 0,05863717 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,04339583 0,05860476 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,04339583 0,05857238 ! liver development GO:0001889 55 25 0,000 0,04339583 0,05854004 ! protein tetramerization GO:0051262 57 25 0,000 0,04339583 0,05850773 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,04509255 0,06076178 ! myelination GO:0042552 50 26 0,000 0,04509255 0,06072829 ! initiation of viral infection GO:0019059 60 26 0,000 0,04509255 0,06069483 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,04509255 0,0606614 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,04509255 0,06062802 ! molting cycle process GO:0022404 52 26 0,000 0,04509255 0,06059467 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,04509255 0,06056136 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,04509255 0,06052808 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,04509255 0,06049484 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,04509255 0,06046164 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,04509255 0,06042848 ! digestive system process GO:0022600 49 26 0,000 0,04509255 0,06039535 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,04509255 0,06036225 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,04509255 0,0603292 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,04509255 0,06029617 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 0,000 0,04509255 0,06026319 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,04509255 0,06023024 ! neural crest cell development GO:0014032 59 26 0,000 0,04509255 0,06019733 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,04509255 0,06016445 ! negative regulation of cell development GO:0010721 83 26 0,000 0,04509255 0,06013161 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,04509255 0,06009881 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,04509255 0,06006604 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,04509255 0,0600333 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,04509255 0,06000061 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,04509255 0,05996794 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,04509255 0,05993532 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,04509255 0,05990273 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,04509255 0,05987017 ! blastocyst development GO:0001824 50 26 0,000 0,04509255 0,05983765 ! telomere organization GO:0032200 46 26 0,000 0,04509255 0,05980516 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,04509255 0,05977271 ! neural tube closure GO:0001843 58 26 0,000 0,04509255 0,0597403 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,04509255 0,05970792 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,04509255 0,05967557 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,04509255 0,05964327 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,04678632 0,0618501 ! embryonic pattern specification GO:0009880 49 27 0,000 0,04678632 0,06181665 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,04678632 0,06178323 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,04678632 0,06174985 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,04678632 0,06171651 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,04678632 0,06168321 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,04678632 0,06164994 ! iron ion transport GO:0006826 65 27 0,000 0,04678632 0,0616167 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,04678632 0,0615835 ! superoxide metabolic process GO:0006801 41 27 0,000 0,04678632 0,06155034 ! tube lumen formation GO:0035148 59 27 0,000 0,04678632 0,06151721 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,04678632 0,06148412 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,04678632 0,06145107 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,04678632 0,06141804 ! response to starvation GO:0042594 47 27 0,000 0,04678632 0,06138506 ! response to toxin GO:0009636 49 27 0,000 0,04678632 0,06135211 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,04678632 0,0613192 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,04678632 0,06128632 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,04678632 0,06125347 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,04678632 0,06122066 ! leukocyte proliferation GO:0070661 59 27 0,000 0,04678632 0,06118789 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,04678632 0,06115515 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,04847713 0,06333135 ! neuron fate commitment GO:0048663 52 28 0,000 0,04847713 0,0632975 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,04847713 0,06326369 ! protein amino acid acylation GO:0043543 59 28 0,000 0,04847713 0,06322991 ! circadian rhythm GO:0007623 56 28 0,000 0,04847713 0,06319617 ! dendrite development GO:0016358 67 28 0,000 0,04847713 0,06316247 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,04847713 0,0631288 ! fat cell differentiation GO:0045444 57 28 0,000 0,04847713 0,06309517 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,04847713 0,06306157 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,04847713 0,06302801 ! base-excision repair GO:0006284 41 28 0,000 0,04847713 0,06299448 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,04847713 0,06296099 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,04847713 0,06292754 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,04847713 0,06289412 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,04847713 0,06286074 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,04847713 0,06282739 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,04847713 0,06279408 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,04847713 0,0627608 ! glutathione metabolic process GO:0006749 42 28 0,000 0,04847713 0,06272756 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,04847713 0,06269435 ! lipid oxidation GO:0034440 48 28 0,000 0,04847713 0,06266118 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,04847713 0,06262804 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,04847713 0,06259494 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05016499 0,06474013 ! translational initiation GO:0006413 66 29 0,000 0,05016499 0,06470595 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05016499 0,0646718 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05016499 0,06463769 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05016499 0,06460362 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,05016499 0,06456958 ! autophagy GO:0006914 47 29 0,000 0,05016499 0,06453558 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05016499 0,06450161 ! primary neural tube formation GO:0014020 61 29 0,000 0,05016499 0,06446768 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,05016499 0,06443379 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05016499 0,06439993 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05016499 0,0643661 ! somitogenesis GO:0001756 52 29 0,000 0,05016499 0,06433232 ! synaptogenesis GO:0007416 46 29 0,000 0,05016499 0,06429856 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05016499 0,06426485 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05016499 0,06423116 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05016499 0,06419752 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05016499 0,06416391 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0518499 0,0662843 ! phenol metabolic process GO:0018958 56 30 0,000 0,0518499 0,06624963 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,0518499 0,066215 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,0518499 0,06618041 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0518499 0,06614585 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0518499 0,06611133 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0518499 0,06607684 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0518499 0,06604239 ! acute-phase response GO:0006953 50 30 0,000 0,0518499 0,06600797 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0518499 0,06597359 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0518499 0,06593925 ! myofibril assembly GO:0030239 50 30 0,000 0,0518499 0,06590494 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,0518499 0,06587067 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0518499 0,06583643 ! cell fate determination GO:0001709 64 30 0,000 0,0518499 0,06580223 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0518499 0,06576807 ! phospholipid transport GO:0015914 65 30 0,000 0,0518499 0,06573394 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,0518499 0,06569984 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0518499 0,06566579 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0518499 0,06563176 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,0518499 0,06559777 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,0518499 0,06556382 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,0518499 0,0655299 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,05353187 0,06762066 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,05353187 0,06758571 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,05353187 0,0675508 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,05353187 0,06751593 ! cell junction assembly GO:0034329 85 31 0,000 0,05353187 0,06748109 ! regulation of innate immune response GO:0045088 57 31 0,000 0,05353187 0,06744629 ! ovulation cycle process GO:0022602 55 31 0,000 0,05353187 0,06741152 ! peptide transport GO:0015833 60 31 0,000 0,05353187 0,06737679 ! male gonad development GO:0008584 56 31 0,000 0,05353187 0,0673421 ! iron ion homeostasis GO:0055072 60 31 0,000 0,05353187 0,06730744 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,05353187 0,06727281 ! detection of light stimulus GO:0009583 44 31 0,000 0,05353187 0,06723823 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,05353187 0,06720367 ! natural killer cell activation GO:0030101 50 31 0,000 0,05353187 0,06716916 ! ensheathment of neurons GO:0007272 64 31 0,000 0,05353187 0,06713468 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,05353187 0,06710023 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,05353187 0,06706582 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,05353187 0,06703145 ! eye morphogenesis GO:0048592 65 31 0,000 0,05353187 0,06699711 ! response to heat GO:0009408 54 31 0,000 0,05353187 0,0669628 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,05353187 0,06692853 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,0552109 0,06899244 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,0552109 0,06895717 ! collagen metabolic process GO:0032963 49 32 0,000 0,0552109 0,06892194 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,0552109 0,06888674 ! spindle organization GO:0007051 50 32 0,000 0,0552109 0,06885157 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,0552109 0,06881644 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,0552109 0,06878135 ! metanephros development GO:0001656 81 32 0,000 0,0552109 0,06874629 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,0552109 0,06871127 ! muscle cell development GO:0055001 52 32 0,000 0,0552109 0,06867629 ! mesoderm formation GO:0001707 73 32 0,000 0,0552109 0,06864134 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,0552109 0,06860642 ! ovulation cycle GO:0042698 57 32 0,000 0,0552109 0,06857154 ! peripheral nervous system development GO:0007422 68 32 0,000 0,0552109 0,0685367 ! BMP signaling pathway GO:0030509 71 32 0,000 0,0552109 0,06850189 ! hindbrain development GO:0030902 65 32 0,000 0,0552109 0,06846712 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,0552109 0,06843238 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,0552109 0,06839768 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,0552109 0,06836301 ! gene silencing GO:0016458 71 32 0,000 0,0552109 0,06832838 ! regulation of pH GO:0006885 56 33 0,000 0,056887 0,07036706 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,056887 0,07033145 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,056887 0,07029587 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,056887 0,07026034 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,056887 0,07022483 ! response to ionizing radiation GO:0010212 74 33 0,000 0,056887 0,07018937 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,056887 0,07015393 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,056887 0,07011854 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,056887 0,07008318 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,056887 0,07004785 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,056887 0,07001257 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,056887 0,06997731 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,056887 0,0699421 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,05856018 0,07196303 ! glial cell differentiation GO:0010001 67 34 0,000 0,05856018 0,07192685 ! post-embryonic development GO:0009791 76 34 0,000 0,05856018 0,07189071 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,05856018 0,0718546 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,05856018 0,07181853 ! spliceosome assembly GO:0000245 75 34 0,000 0,05856018 0,07178249 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,05856018 0,07174649 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,05856018 0,07171053 ! formation of primary germ layer GO:0001704 76 34 0,000 0,05856018 0,0716746 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,05856018 0,07163871 ! adult locomotory behavior GO:0008344 62 34 0,000 0,05856018 0,07160286 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,05856018 0,07156704 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,06023043 0,07357147 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06023043 0,0735347 ! negative regulation of secretion GO:0051048 68 35 0,000 0,06023043 0,07349797 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,06023043 0,07346128 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,06023043 0,07342462 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06023043 0,073388 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06023043 0,07335142 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06023043 0,07331487 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,06023043 0,07327836 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06023043 0,07324188 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,06023043 0,07320544 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06023043 0,07316904 ! telencephalon development GO:0021537 81 35 0,000 0,06023043 0,07313267 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,06023043 0,07309634 ! placenta development GO:0001890 53 35 0,000 0,06023043 0,07306005 ! vesicle localization GO:0051648 70 35 0,000 0,06023043 0,07302379 ! regulation of muscle development GO:0048634 82 36 0,000 0,06189777 0,07500806 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,06189777 0,07497087 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,06189777 0,07493372 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,06189777 0,0748966 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,06189777 0,07485953 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,06189777 0,07482249 ! positive regulation of cell development GO:0010720 85 36 0,000 0,06189777 0,07478548 ! protein targeting to membrane GO:0006612 75 36 0,000 0,06189777 0,07474851 ! regulation of proteolysis GO:0030162 77 36 0,000 0,06189777 0,07471158 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,06189777 0,07467469 ! aerobic respiration GO:0009060 56 36 0,000 0,06189777 0,07463783 ! cytokine production GO:0001816 68 36 0,000 0,06189777 0,07460101 ! embryonic organ development GO:0048568 67 36 0,000 0,06189777 0,07456422 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,06189777 0,07452747 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,06189777 0,07449076 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,06356219 0,07645615 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,06356219 0,07641852 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,06356219 0,07638093 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,06356219 0,07634338 ! sister chromatid segregation GO:0000819 65 37 0,000 0,06356219 0,07630587 ! odontogenesis GO:0042476 74 37 0,000 0,06356219 0,07626839 ! actomyosin structure organization GO:0031032 68 37 0,000 0,06356219 0,07623095 ! cell junction organization GO:0034330 96 37 0,000 0,06356219 0,07619354 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,06356219 0,07615617 ! female gonad development GO:0008585 71 37 0,000 0,06356219 0,07611884 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,06356219 0,07608155 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,06356219 0,07604429 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,06522371 0,0779939 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,06522371 0,07795574 ! meiosis I GO:0007127 74 38 0,000 0,06522371 0,07791762 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,06522371 0,07787954 ! organic anion transport GO:0015711 82 38 0,000 0,06522371 0,07784149 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,06522371 0,07780348 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,06522371 0,07776551 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,06522371 0,07772758 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,06522371 0,07768968 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,06522371 0,07765182 ! regulation of protein stability GO:0031647 77 38 0,000 0,06522371 0,07761399 ! spermatid development GO:0007286 69 38 0,000 0,06522371 0,07757621 ! glycogen metabolic process GO:0005977 63 38 0,000 0,06522371 0,07753846 ! pigment metabolic process GO:0042440 87 38 0,000 0,06522371 0,07750074 ! neural tube formation GO:0001841 79 38 0,000 0,06522371 0,07746307 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,06688233 0,07939433 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,06688233 0,07935577 ! negative regulation of binding GO:0051100 71 39 0,000 0,06688233 0,07931725 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,06688233 0,07927877 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,06688233 0,07924032 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,06688233 0,07920191 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,06688233 0,07916353 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,06688233 0,0791252 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,06688233 0,0790869 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,06688233 0,07904864 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,06688233 0,07901041 ! glucan metabolic process GO:0044042 64 39 0,000 0,06688233 0,07897223 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,06853805 0,08088815 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,06853805 0,08084909 ! learning GO:0007612 82 40 0,000 0,06853805 0,08081007 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,06853805 0,08077109 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,06853805 0,08073214 ! mismatch repair GO:0006298 58 40 0,000 0,06853805 0,08069324 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,06853805 0,08065437 ! RNA export from nucleus GO:0006405 61 41 0,000 0,07019088 0,08255962 ! mRNA catabolic process GO:0006402 79 41 0,000 0,07019088 0,08251989 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,07019088 0,0824802 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,07019088 0,08244054 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,07019088 0,08240093 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,07019088 0,08236135 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,07019088 0,08232181 ! gliogenesis GO:0042063 91 41 0,000 0,07019088 0,08228231 ! feeding behavior GO:0007631 69 41 0,000 0,07019088 0,08224284 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,07019088 0,08220342 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,07019088 0,08216403 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,07019088 0,08212468 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,07019088 0,08208537 ! spermatid differentiation GO:0048515 73 41 0,000 0,07019088 0,08204609 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,07019088 0,08200685 ! RNA modification GO:0009451 64 41 0,000 0,07019088 0,08196765 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,07184083 0,08385435 ! ear morphogenesis GO:0042471 64 42 0,000 0,07184083 0,0838143 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,07184083 0,08377429 ! T cell differentiation GO:0030217 93 42 0,000 0,07184083 0,08373432 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,07184083 0,08369439 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,07184083 0,0836545 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,07184083 0,08361465 ! regulation of protein secretion GO:0050708 77 42 0,000 0,07184083 0,08357483 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,07184083 0,08353505 ! cytokinesis GO:0000910 84 42 0,000 0,07184083 0,08349531 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,07184083 0,08345561 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,07348789 0,08532838 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,07348789 0,08528785 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,07348789 0,08524735 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,07348789 0,08520689 ! glucose transport GO:0015758 66 43 0,000 0,07348789 0,08516647 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,07348789 0,08512609 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,07348789 0,08508574 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,07348789 0,08504544 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,07348789 0,08500517 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,07348789 0,08496494 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,07348789 0,08492475 ! segmentation GO:0035282 78 43 0,000 0,07348789 0,0848846 ! ion transmembrane transport GO:0034220 79 43 0,000 0,07348789 0,08484448 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,07348789 0,0848044 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,07513208 0,08666084 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,07513208 0,08661995 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,07513208 0,08657909 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,07513208 0,08653827 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,07513208 0,08649749 ! hexose transport GO:0008645 68 44 0,000 0,07513208 0,08645674 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,07513208 0,08641604 ! striated muscle contraction GO:0006941 85 44 0,000 0,07513208 0,08637537 ! phagocytosis GO:0006909 105 44 0,000 0,07513208 0,08633474 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,07513208 0,08629415 ! double-strand break repair GO:0006302 85 44 0,000 0,07513208 0,0862536 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,07677339 0,08809648 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,07677339 0,08805512 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,07677339 0,0880138 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,07677339 0,08797251 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,07677339 0,08793127 ! biopolymer methylation GO:0043414 91 45 0,000 0,07677339 0,08789007 ! B cell differentiation GO:0030183 124 45 0,000 0,07677339 0,0878489 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,07677339 0,08780777 ! female gamete generation GO:0007292 71 45 0,000 0,07677339 0,08776668 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,07677339 0,08772563 ! polyol metabolic process GO:0019751 77 45 0,000 0,07677339 0,08768462 ! developmental growth GO:0048589 88 45 0,000 0,07677339 0,08764364 ! maintenance of location in cell GO:0051651 101 45 0,000 0,07677339 0,08760271 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,07841184 0,0894305 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,07841184 0,08938877 ! glycolysis GO:0006096 71 46 0,000 0,07841184 0,08934707 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,07841184 0,08930542 ! leukocyte migration GO:0050900 75 46 0,000 0,07841184 0,08926381 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,07841184 0,08922223 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,07841184 0,08918069 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,07841184 0,08913919 ! pigmentation GO:0043473 103 46 0,000 0,07841184 0,08909773 ! neural tube development GO:0021915 91 47 0,000 0,08004743 0,09091393 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,08004743 0,09087168 ! positive regulation of defense response GO:0031349 88 48 0,000 0,08168016 0,09268213 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,08168016 0,0926391 ! mitochondrial transport GO:0006839 94 48 0,000 0,08168016 0,09259611 ! cellular component disassembly GO:0022411 89 48 0,000 0,08168016 0,09255317 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,08168016 0,09251026 ! endosome transport GO:0016197 127 48 0,000 0,08168016 0,09246739 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,08168016 0,09242456 ! male sex differentiation GO:0046661 93 48 0,000 0,08168016 0,09238177 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,08168016 0,09233902 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,08168016 0,09229631 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,08168016 0,09225364 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,08168016 0,09221101 ! methylation GO:0032259 97 48 0,000 0,08168016 0,09216842 ! response to calcium ion GO:0051592 94 49 0,000 0,08331004 0,09396418 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,08331004 0,09392082 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,08331004 0,0938775 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,08331004 0,09383422 ! JNK cascade GO:0007254 106 49 0,000 0,08331004 0,09379098 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,08331004 0,09374777 ! regulation of action potential GO:0001508 102 50 0,000 0,08493707 0,09553465 ! regulation of ion transport GO:0043269 86 50 0,000 0,08493707 0,09549068 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,08493707 0,09544676 ! endocrine system development GO:0035270 109 50 0,000 0,08493707 0,09540288 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,08493707 0,09535903 ! activation of caspase activity GO:0006919 95 50 0,000 0,08493707 0,09531523 ! regulation of ossification GO:0030278 123 50 0,000 0,08493707 0,09527147 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,08493707 0,09522774 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,08493707 0,09518406 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,08493707 0,09514042 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,08493707 0,09509682 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,08493707 0,09505325 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,08656126 0,09682653 ! viral infectious cycle GO:0019058 104 51 0,000 0,08656126 0,09678222 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,08656126 0,09673795 ! peptide metabolic process GO:0006518 80 51 0,000 0,08656126 0,09669371 ! response to temperature stimulus GO:0009266 84 51 0,000 0,08656126 0,09664952 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,08656126 0,09660537 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,08656126 0,09656125 ! positive regulation of binding GO:0051099 88 52 0,000 0,08818261 0,09832502 ! Notch signaling pathway GO:0007219 111 52 0,000 0,08818261 0,09828016 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,08818261 0,09823534 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,08818261 0,09819057 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,08818261 0,09814584 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,08818261 0,09810114 ! excretion GO:0007588 87 52 0,000 0,08818261 0,09805649 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,08818261 0,09801188 ! histone modification GO:0016570 104 52 0,000 0,08818261 0,09796731 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,08818261 0,09792278 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,08818261 0,09787829 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,08818261 0,09783384 ! amino acid activation GO:0043038 98 52 0,000 0,08818261 0,09778943 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,08980113 0,09953909 ! positive regulation of growth GO:0045927 96 53 0,000 0,08980113 0,09949395 ! inner ear development GO:0048839 89 53 0,000 0,08980113 0,09944885 ! chromatin remodeling GO:0006338 122 53 0,000 0,08980113 0,09940379 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,08980113 0,09935877 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,08980113 0,09931379 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,08980113 0,09926885 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,08980113 0,09922395 ! cartilage development GO:0051216 99 53 0,000 0,08980113 0,09917909 ! synapse organization GO:0050808 102 53 0,000 0,08980113 0,09913428 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,09141682 0,10087231 ! regulation of translational initiation GO:0006446 87 54 0,000 0,09141682 0,10082677 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,09141682 0,10078127 ! neuromuscular process GO:0050905 107 54 0,000 0,09141682 0,10073581 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,09141682 0,10069039 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,09141682 0,10064502 ! covalent chromatin modification GO:0016569 115 54 0,000 0,09141682 0,10059968 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,09141682 0,10055439 ! regulation of cell shape GO:0008360 142 54 0,000 0,09141682 0,10050913 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,09141682 0,10046392 ! RNA catabolic process GO:0006401 103 55 0,000 0,09302969 0,10219044 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,09302969 0,10214451 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,09302969 0,10209862 ! cell recognition GO:0008037 98 55 0,000 0,09302969 0,10205277 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,09302969 0,10200697 ! cell maturation GO:0048469 107 55 0,000 0,09302969 0,10196121 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,09302969 0,10191548 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,09463974 0,10363285 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,09463974 0,10358642 ! glucose catabolic process GO:0006007 88 56 0,000 0,09463974 0,10354003 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,09463974 0,10349368 ! regulation of DNA replication GO:0006275 105 56 0,000 0,09463974 0,10344738 ! RNA elongation GO:0006354 90 56 0,000 0,09463974 0,10340111 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,09624698 0,10511013 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,09624698 0,10506317 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,09624698 0,10501624 ! heart morphogenesis GO:0003007 105 57 0,000 0,09624698 0,10496936 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,09624698 0,10492252 ! regulation of actin filament length GO:0030832 118 58 0,000 0,09785141 0,10662399 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,09785141 0,10657646 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,09785141 0,10652896 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,09785141 0,10648151 ! aging GO:0007568 112 58 0,000 0,09785141 0,1064341 ! gastrulation GO:0007369 122 58 0,000 0,09785141 0,10638674 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,09785141 0,10633941 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,09785141 0,10629213 ! maintenance of location GO:0051235 124 58 0,000 0,09785141 0,10624489 ! nuclear export GO:0051168 110 59 0,000 0,09945304 0,10793593 ! establishment of organelle localization GO:0051656 122 59 0,000 0,09945304 0,107888 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,10105187 0,10957377 ! DNA catabolic process GO:0006308 94 60 0,000 0,10105187 0,10952516 ! regulation of endocytosis GO:0030100 104 60 0,000 0,10105187 0,10947659 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,10105187 0,10942806 ! adult behavior GO:0030534 104 60 0,000 0,10105187 0,10937958 ! kidney development GO:0001822 133 60 0,000 0,10105187 0,10933114 ! positive regulation of secretion GO:0051047 110 61 0,000 0,1026479 0,11100878 ! regulation of cellular component size GO:0032535 125 61 0,000 0,1026479 0,11095966 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,1026479 0,11091058 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,1026479 0,11086155 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,1026479 0,11081256 ! regulation of heart contraction GO:0008016 123 61 0,000 0,1026479 0,11076362 ! camera-type eye development GO:0043010 126 61 0,000 0,1026479 0,11071471 ! proton transport GO:0015992 117 61 0,000 0,1026479 0,11066586 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,1026479 0,11061704 ! viral reproductive process GO:0022415 132 62 0,000 0,10424115 0,11228445 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,10424115 0,11223496 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,10424115 0,11218552 ! tRNA processing GO:0008033 102 62 0,000 0,10424115 0,11213612 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,10424115 0,11208677 ! regulation of mitosis GO:0007088 112 63 0,000 0,10583161 0,11374687 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,10583161 0,11369685 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,10583161 0,11364687 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,10583161 0,11359694 ! hydrogen transport GO:0006818 121 64 0,000 0,1074193 0,11525048 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,1074193 0,11519989 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,1074193 0,11514934 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,10900421 0,11679705 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,10900421 0,11674585 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,10900421 0,11669469 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,10900421 0,11664357 ! ear development GO:0043583 114 66 0,000 0,11058635 0,11828478 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,11058635 0,11823302 ! gonad development GO:0008406 115 66 0,000 0,11058635 0,1181813 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,11216572 0,11981673 ! activation of MAPK activity GO:0000187 124 67 0,000 0,11216572 0,11976436 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,11216572 0,11971204 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,11216572 0,11965976 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,11216572 0,11960753 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,11216572 0,11955535 ! secondary metabolic process GO:0019748 125 67 0,000 0,11216572 0,11950321 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,11216572 0,11945111 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,11374234 0,12107735 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,11374234 0,12102462 ! hexose catabolic process GO:0019320 113 68 0,000 0,11374234 0,12097193 ! extracellular matrix organization GO:0030198 146 68 0,000 0,11374234 0,12091929 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,11374234 0,12086669 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,11374234 0,12081414 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,11374234 0,12076164 ! viral reproduction GO:0016032 142 68 0,000 0,11374234 0,12070918 ! adaptive immune response GO:0002250 126 68 0,000 0,11374234 0,12065676 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,11374234 0,12060439 ! cell projection assembly GO:0030031 138 68 0,000 0,11374234 0,12055207 ! negative regulation of cell size GO:0045792 144 69 0,000 0,11531619 0,12216716 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,11531619 0,1221142 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,11531619 0,12206129 ! urogenital system development GO:0001655 149 69 0,000 0,11531619 0,12200843 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,11531619 0,12195561 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,11531619 0,12190284 ! developmental maturation GO:0021700 128 69 0,000 0,11531619 0,12185011 ! single fertilization GO:0007338 83 69 0,000 0,11531619 0,12179743 ! cell redox homeostasis GO:0045454 114 70 0,000 0,1168873 0,12340349 ! germ cell development GO:0007281 133 70 0,000 0,1168873 0,12335019 ! activation of immune response GO:0002253 120 70 0,000 0,1168873 0,12329693 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,1168873 0,12324371 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,11845567 0,12484348 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,11845567 0,12478965 ! appendage morphogenesis GO:0035107 150 72 0,000 0,12002129 0,12638449 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,12002129 0,12633003 ! actin filament organization GO:0007015 167 72 0,000 0,12002129 0,12627563 ! B cell activation GO:0042113 179 72 0,000 0,12002129 0,12622127 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,12002129 0,12616696 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,12002129 0,12611269 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,12002129 0,12605847 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,12002129 0,1260043 ! appendage development GO:0048736 151 73 0,000 0,12158417 0,12759026 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,12158417 0,12753548 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,12158417 0,12748074 ! regulation of immune effector process GO:0002697 156 73 0,000 0,12158417 0,12742606 ! acute inflammatory response GO:0002526 118 74 0,000 0,12314433 0,12900583 ! amino acid transport GO:0006865 148 74 0,000 0,12314433 0,12895053 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,12314433 0,12889528 ! organelle localization GO:0051640 155 74 0,000 0,12314433 0,12884008 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,12470175 0,13041369 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,12470175 0,13035789 ! reproductive structure development GO:0048608 131 75 0,000 0,12470175 0,13030213 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,12470175 0,13024642 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,12470175 0,13019076 ! eye development GO:0001654 155 75 0,000 0,12470175 0,13013515 ! rhythmic process GO:0048511 142 75 0,000 0,12470175 0,13007958 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,12625646 0,13164512 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,12625646 0,13158896 ! learning or memory GO:0007611 161 76 0,000 0,12625646 0,13153285 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,12625646 0,13147678 ! regulation of blood pressure GO:0008217 134 76 0,000 0,12625646 0,13142076 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,12625646 0,13136479 ! amine catabolic process GO:0009310 136 77 0,000 0,12780844 0,13292296 ! neurotransmitter transport GO:0006836 142 77 0,000 0,12780844 0,13286639 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,12780844 0,13280988 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,12780844 0,13275341 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,12780844 0,13269699 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,12780844 0,13264062 ! regulation of catabolic process GO:0009894 173 77 0,000 0,12780844 0,1325843 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,12935772 0,13413451 ! antigen processing and presentation GO:0019882 117 78 0,000 0,12935772 0,1340776 ! fertilization GO:0009566 99 78 0,000 0,12935772 0,13402074 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,12935772 0,13396392 ! blood coagulation GO:0007596 151 79 0,000 0,13090428 0,13550812 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,13090428 0,13545072 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,13090428 0,13539338 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,13090428 0,13533608 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,13090428 0,13527883 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,13244814 0,13681641 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,13244814 0,13675858 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,13244814 0,13670081 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,13244814 0,13664308 ! meiosis GO:0007126 143 81 0,000 0,1339893 0,1381747 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,1339893 0,1381164 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,1339893 0,13805815 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,13552777 0,13958446 ! protein import into nucleus GO:0006606 174 82 0,000 0,13552777 0,13952564 ! meiotic cell cycle GO:0051321 144 82 0,000 0,13552777 0,13946687 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,13706355 0,14098789 ! exocytosis GO:0006887 153 83 0,000 0,13706355 0,14092856 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,13706355 0,14086927 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,13706355 0,14081003 ! nuclear import GO:0051170 177 83 0,000 0,13706355 0,14075084 ! response to metal ion GO:0010038 158 84 0,000 0,13859664 0,14226538 ! T cell activation GO:0042110 189 84 0,000 0,13859664 0,14220563 ! response to nutrient GO:0007584 135 84 0,000 0,13859664 0,14214593 ! digestion GO:0007586 130 84 0,000 0,13859664 0,14208628 ! regulation of ligase activity GO:0051340 147 84 0,000 0,13859664 0,14202668 ! hemostasis GO:0007599 165 85 0,000 0,14012705 0,14353475 ! negative regulation of transport GO:0051051 164 85 0,000 0,14012705 0,1434746 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,14012705 0,14341449 ! negative regulation of growth GO:0045926 168 85 0,000 0,14012705 0,14335443 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,14012705 0,14329443 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,14012705 0,14323447 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,14012705 0,14317457 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,14165479 0,14467502 ! regulation of lyase activity GO:0051339 169 86 0,000 0,14165479 0,14461456 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,14165479 0,14455416 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,14317985 0,14604943 ! mitochondrion organization GO:0007005 159 87 0,000 0,14317985 0,14598847 ! alcohol catabolic process GO:0046164 142 87 0,000 0,14317985 0,14592757 ! nucleosome assembly GO:0006334 126 87 0,000 0,14317985 0,14586672 ! cellular respiration GO:0045333 143 88 0,000 0,14470225 0,14735623 ! amine biosynthetic process GO:0009309 146 88 0,000 0,14470225 0,14729483 ! sensory perception of smell GO:0007608 117 88 0,000 0,14470225 0,14723349 ! chromatin assembly GO:0031497 128 88 0,000 0,14470225 0,14717219 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,14470225 0,14711095 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,14622199 0,14859414 ! regulation of DNA binding GO:0051101 167 89 0,000 0,14622199 0,14853236 ! tube morphogenesis GO:0035239 194 89 0,000 0,14622199 0,14847062 ! cellular defense response GO:0006968 123 89 0,000 0,14622199 0,14840894 ! protein localization in nucleus GO:0034504 192 89 0,000 0,14622199 0,14834731 ! regulation of neurological system process GO:0031644 175 89 0,000 0,14622199 0,14828573 ! response to inorganic substance GO:0010035 173 90 0,000 0,14773907 0,14976205 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,14773907 0,14969993 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,14773907 0,14963787 ! response to unfolded protein GO:0006986 139 90 0,000 0,14773907 0,14957586 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,14773907 0,14951389 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,14925349 0,15098397 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,14925349 0,15092147 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,15076527 0,15238707 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,15076527 0,15232405 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,1522744 0,15378519 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,1522744 0,15372164 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,1522744 0,15365814 ! vitamin metabolic process GO:0006766 153 93 0,000 0,1522744 0,1535947 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,1537809 0,15505024 ! female pregnancy GO:0007565 166 94 0,000 0,1537809 0,15498627 ! sterol metabolic process GO:0016125 166 94 0,000 0,1537809 0,15492236 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,1537809 0,1548585 ! regulation of defense response GO:0031347 171 95 0,000 0,15528475 0,15630847 ! nucleosome organization GO:0034728 143 95 0,000 0,15528475 0,15624409 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,15528475 0,15617977 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,15528475 0,1561155 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,15528475 0,15605128 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,15528475 0,15598711 ! sex differentiation GO:0007548 171 96 0,000 0,15678598 0,1574304 ! response to protein stimulus GO:0051789 158 96 0,000 0,15678598 0,15736572 ! regulation of T cell activation GO:0050863 175 96 0,000 0,15678598 0,15730109 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,15828459 0,15873943 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,15828459 0,15867429 ! transcription initiation GO:0006352 171 97 0,000 0,15828459 0,15860921 ! leukocyte differentiation GO:0002521 232 98 0,000 0,15978057 0,16004261 ! forebrain development GO:0030900 210 98 0,000 0,15978057 0,15997702 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,15978057 0,15991148 ! positive regulation of immune response GO:0050778 175 100 0,000 0,16276469 0,16283134 ! hormone metabolic process GO:0042445 171 100 0,000 0,16276469 0,16276469