pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1223-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 5,000 1,718E-13 4,197E-10 ! androgen receptor signaling pathway GO:0030521 81 37 5,000 8,16E-10 9,967E-07 ! steroid hormone receptor signaling pathway GO:0030518 146 66 5,000 2,99E-08 2,435E-05 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 5,000 4,661E-08 2,847E-05 ! cell aging GO:0007569 48 22 3,000 3,825E-07 1,869E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 4,04E-07 1,645E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 1,127E-06 3,932E-04 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 3,000 1,614E-06 4,93E-04 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 3,3E-06 8,958E-04 ! regulation of microtubule-based process GO:0032886 86 37 3,000 3,346E-06 8,174E-04 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 4,391E-06 9,753E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 8,111E-06 1,651E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 8,795E-06 1,653E-03 GO:0060538|skeletal muscle organ development, ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 9,027E-06 1,575E-03 ! myoblast differentiation GO:0045445 50 17 2,000 1,344E-05 2,189E-03 ! detection of bacterium GO:0016045 22 18 2,000 1,609E-05 2,457E-03 ! negative regulation of cytoskeleton organization GO:0051494 139 56 3,000 1,788E-05 2,569E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 1,907E-05 2,589E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,918E-05 2,467E-03 ! aging GO:0007568 112 58 3,000 2,056E-05 2,512E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 2,239E-05 2,605E-03 ! pancreas development GO:0031016 40 20 2,000 2,239E-05 2,487E-03 ! regulation of fatty acid metabolic process GO:0019217 45 20 2,000 2,239E-05 2,379E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,607E-05 2,654E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 3,013E-05 2,944E-03 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 3,434E-05 3,227E-03 ! detection of biotic stimulus GO:0009595 34 24 2,000 3,944E-05 3,569E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 3,944E-05 3,441E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 4,094E-05 3,448E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 4,332E-05 3,528E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 4,473E-05 3,525E-03 ! regulation of cellular ketone metabolic process GO:0010565 51 26 2,000 5,046E-05 3,852E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 5,391E-05 3,991E-03 ! fat cell differentiation GO:0045444 57 28 2,000 6,333E-05 4,55E-03 ! steroid biosynthetic process GO:0006694 146 79 3,000 6,966E-05 4,862E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 7,049E-05 4,784E-03 ! negative regulation of organelle organization GO:0010639 181 80 3,000 7,317E-05 4,831E-03 ! microvillus organization GO:0032528 8 5 1,000 7,484E-05 4,811E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 7,484E-05 4,688E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 7,484E-05 4,571E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 7,484E-05 4,459E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 7,484E-05 4,353E-03 ! muscle cell differentiation GO:0042692 178 81 3,000 7,681E-05 4,364E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 8,058E-05 4,474E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 1,121E-04 6,083E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 1,121E-04 5,951E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,121E-04 5,825E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 1,121E-04 5,703E-03 ! positive regulation of protein ubiquitination GO:0031398 14 7 1,000 1,566E-04 7,808E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,566E-04 7,651E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,566E-04 7,501E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 1,566E-04 7,357E-03 ! vesicle fusion GO:0006906 20 7 1,000 1,566E-04 7,218E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 1,566E-04 7,085E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 1,609E-04 7,147E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 1,728E-04 7,539E-03 GO:0042593|glucose homeostasis, ! regulation of hormone secretion GO:0046883 69 41 2,000 2,008E-04 8,605E-03 ! mesenchymal cell development GO:0014031 94 41 2,000 2,008E-04 8,457E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,084E-04 8,63E-03 ! male meiosis GO:0007140 9 8 1,000 2,084E-04 8,486E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 2,084E-04 8,347E-03 ! ER overload response GO:0006983 13 8 1,000 2,084E-04 8,212E-03 ! negative regulation of translational initiation GO:0045947 12 8 1,000 2,084E-04 8,082E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 2,084E-04 7,956E-03 ! gas homeostasis GO:0033483 14 8 1,000 2,084E-04 7,833E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 2,084E-04 7,715E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 2,084E-04 7,6E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 2,084E-04 7,488E-03 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 2,158E-04 7,64E-03 ! negative regulation of protein complex disassembly GO:0043242 113 44 2,000 2,48E-04 8,654E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 2,651E-04 9,123E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 2,675E-04 9,076E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 2,675E-04 8,952E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 2,675E-04 8,831E-03 ! glycine catabolic process GO:0006546 15 9 1,000 2,675E-04 8,713E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 2,675E-04 8,598E-03 ! postreplication repair GO:0006301 25 9 1,000 2,675E-04 8,487E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 2,675E-04 8,378E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 2,675E-04 8,272E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 2,831E-04 8,644E-03 ! positive regulation of protein transport GO:0051222 80 46 2,000 2,831E-04 8,537E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,338E-04 9,944E-03 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 1,000 3,338E-04 9,824E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 3,338E-04 9,707E-03 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 3,338E-04 9,593E-03 ! induction of an organ GO:0001759 17 10 1,000 3,338E-04 9,481E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 3,338E-04 9,372E-03 ! midbrain development GO:0030901 14 10 1,000 3,338E-04 9,266E-03 ! serine family amino acid catabolic process GO:0009071 18 10 1,000 3,338E-04 9,161E-03 ! protein homooligomerization GO:0051260 84 49 2,000 3,415E-04 9,27E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 4,072E-04 0,01093159 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 4,072E-04 0,01081277 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 4,072E-04 0,0106965 ! regulation of embryonic development GO:0045995 35 11 1,000 4,072E-04 0,01058271 ! response to estrogen stimulus GO:0043627 98 52 2,000 4,072E-04 0,01047153 ! regulation of protein complex disassembly GO:0043244 127 52 2,000 4,072E-04 0,01036245 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 2,000 4,072E-04 0,01025562 ! regulation of translational initiation GO:0006446 87 54 2,000 4,552E-04 0,0113476 ! regulation of protein polymerization GO:0032271 117 55 2,000 4,805E-04 0,01185735 ! response to UV GO:0009411 120 55 2,000 4,805E-04 0,01173878 ! regulation of B cell proliferation GO:0030888 22 12 1,000 4,878E-04 0,01179786 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 4,878E-04 0,0116822 ! histone acetylation GO:0016573 27 12 1,000 4,878E-04 0,01156878 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,878E-04 0,01145754 ! developmental induction GO:0031128 22 12 1,000 4,878E-04 0,01134842 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 4,878E-04 0,01124136 ! skeletal muscle fiber development GO:0048741 130 56 2,000 5,067E-04 0,01156871 ! RNA elongation GO:0006354 90 56 2,000 5,067E-04 0,01146159 ! muscle fiber development GO:0048747 131 57 2,000 5,338E-04 0,01196346 ! regulation of intracellular transport GO:0032386 108 57 2,000 5,338E-04 0,01185471 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 5,754E-04 0,01266401 GO:0000725|recombinational repair, ! organelle fusion GO:0048284 36 13 1,000 5,754E-04 0,01255094 ! negative regulation of lipid metabolic process GO:0045833 20 13 1,000 5,754E-04 0,01243987 ! regulation of DNA repair GO:0006282 23 13 1,000 5,754E-04 0,01233075 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 5,754E-04 0,01222352 ! gland morphogenesis GO:0022612 31 13 1,000 5,754E-04 0,01211815 ! positive regulation of secretion GO:0051047 110 61 2,000 6,513E-04 0,01360007 ! lipid localization GO:0010876 32 14 1,000 6,701E-04 0,01387325 GO:0019915|lipid storage, ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 6,701E-04 0,01375666 GO:0060675|ureteric bud morphogenesis, ! positive regulation of protein polymerization GO:0032273 27 14 1,000 6,701E-04 0,01364202 ! regulation of protein complex assembly GO:0043254 132 63 2,000 7,158E-04 0,01445237 ! mesoderm development GO:0007498 128 63 2,000 7,158E-04 0,01433391 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 7,718E-04 0,01532929 ! regulation of vasodilation GO:0042312 27 15 1,000 7,718E-04 0,01520567 ! negative regulation of cell growth GO:0030308 142 67 2,000 8,567E-04 0,01674259 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 8,805E-04 0,01707135 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 8,805E-04 0,01693693 ! detection of external stimulus GO:0009581 102 68 2,000 8,944E-04 0,01707077 ! negative regulation of cell size GO:0045792 144 69 2,000 9,332E-04 0,01767313 ! lung development GO:0030324 165 69 2,000 9,332E-04 0,01753719 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 9,961E-04 0,01857566 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 9,961E-04 0,01843494 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 9,961E-04 0,01829633 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 9,961E-04 0,01815979 GO:0031114|regulation of microtubule depolymerization, ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 9,961E-04 0,01802527 ! cell cycle checkpoint GO:0000075 145 71 2,000 1,014E-03 0,01821408 ! respiratory tube development GO:0030323 171 72 2,000 1,056E-03 0,01882973 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 1,119E-03 0,01980199 ! centrosome cycle GO:0007098 26 18 1,000 1,119E-03 0,01965953 ! glycine metabolic process GO:0006544 30 18 1,000 1,119E-03 0,0195191 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 1,119E-03 0,01938067 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 1,119E-03 0,01924418 ! regulation of caspase activity GO:0043281 136 74 2,000 1,143E-03 0,01952979 ! respiratory system development GO:0060541 175 74 2,000 1,143E-03 0,01939417 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 1,248E-03 0,02102541 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 1,282E-03 0,02145687 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 1,381E-03 0,02294671 ! protein oligomerization GO:0051259 149 79 2,000 1,381E-03 0,02279167 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,384E-03 0,02269361 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,384E-03 0,02254232 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 1,384E-03 0,02239303 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 1,384E-03 0,02224571 ! negative regulation of translation GO:0017148 32 20 1,000 1,384E-03 0,02210031 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 2,000 1,432E-03 0,02271184 ! response to hypoxia GO:0001666 178 81 2,000 1,484E-03 0,02338665 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 2,000 1,484E-03 0,02323673 ! lipid phosphorylation GO:0046834 43 21 1,000 1,527E-03 0,02376162 ! regulation of vasoconstriction GO:0019229 40 21 1,000 1,527E-03 0,02361123 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 1,527E-03 0,02346273 ! response to oxygen levels GO:0070482 183 83 2,000 1,592E-03 0,02430117 ! inactivation of MAPK activity GO:0000188 45 22 1,000 1,677E-03 0,02544268 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,677E-03 0,02528563 ! ureteric bud development GO:0001657 50 22 1,000 1,677E-03 0,0251305 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 1,677E-03 0,02497727 ! G1 phase GO:0051318 44 22 1,000 1,677E-03 0,02482589 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,677E-03 0,02467633 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,677E-03 0,02452857 ! negative regulation of growth GO:0045926 168 85 2,000 1,704E-03 0,02478051 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 1,704E-03 0,02463388 ! regulation of protein transport GO:0051223 165 87 2,000 1,822E-03 0,02617607 GO:0070201|regulation of establishment of protein localization, ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,996E-03 0,02851877 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,996E-03 0,02835297 ! barbed-end actin filament capping GO:0051016 58 24 1,000 1,996E-03 0,02818908 GO:0051693|actin filament capping, ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,996E-03 0,02802707 ! membrane depolarization GO:0051899 45 24 1,000 1,996E-03 0,02786692 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,996E-03 0,02770858 ! ossification GO:0001503 205 91 2,000 2,071E-03 0,02858679 ! bone development GO:0060348 206 92 2,000 2,137E-03 0,02932607 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 2,166E-03 0,02956017 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,166E-03 0,02939595 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 2,166E-03 0,02923354 ! vasculogenesis GO:0001570 49 25 1,000 2,166E-03 0,02907291 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 2,166E-03 0,02891405 ! protein amino acid alkylation GO:0008213 59 26 1,000 2,342E-03 0,03109748 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 2,342E-03 0,03092939 ! microtubule organizing center organization GO:0031023 42 26 1,000 2,342E-03 0,0307631 GO:0051297|centrosome organization, ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 2,342E-03 0,03059859 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,342E-03 0,03043583 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 1,000 2,342E-03 0,0302748 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,342E-03 0,03011545 ! response to estradiol stimulus GO:0032355 43 26 1,000 2,342E-03 0,02995778 ! regulation of blood coagulation GO:0030193 46 26 1,000 2,342E-03 0,02980175 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 2,342E-03 0,02964734 ! transcription initiation GO:0006352 171 97 2,000 2,484E-03 0,03127915 ! regulation of protein localization GO:0032880 188 97 2,000 2,484E-03 0,03111874 ! embryonic pattern specification GO:0009880 49 27 1,000 2,525E-03 0,03147254 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 2,525E-03 0,03131278 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 2,525E-03 0,03115464 ! iron ion transport GO:0006826 65 27 1,000 2,525E-03 0,03099808 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 2,525E-03 0,03084309 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 2,525E-03 0,03068964 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,714E-03 0,03282786 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 2,714E-03 0,03266614 ! protein amino acid acylation GO:0043543 59 28 1,000 2,714E-03 0,03250601 ! vesicle docking GO:0048278 55 28 1,000 2,714E-03 0,03234745 ! dendrite development GO:0016358 67 28 1,000 2,714E-03 0,03219042 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 2,714E-03 0,03203491 ! translational initiation GO:0006413 66 29 1,000 2,91E-03 0,03418112 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 2,91E-03 0,03401757 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,91E-03 0,03385558 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 2,91E-03 0,03369513 ! somitogenesis GO:0001756 52 29 1,000 2,91E-03 0,03353619 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 3,113E-03 0,0356989 ! negative regulation of protein complex assembly GO:0031333 68 30 1,000 3,113E-03 0,03553208 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 3,113E-03 0,03536682 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 3,113E-03 0,03520308 ! regulation of B cell activation GO:0050864 55 30 1,000 3,113E-03 0,03504085 ! regulation of coagulation GO:0050818 52 30 1,000 3,113E-03 0,03488012 ! iron ion homeostasis GO:0055072 60 31 1,000 3,321E-03 0,03704894 ! erythrocyte differentiation GO:0030218 62 31 1,000 3,321E-03 0,03688054 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 3,321E-03 0,03671366 ! response to heat GO:0009408 54 31 1,000 3,321E-03 0,03654828 ! metanephros development GO:0001656 81 32 1,000 3,536E-03 0,03874054 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 3,536E-03 0,03856759 ! mesoderm formation GO:0001707 73 32 1,000 3,536E-03 0,03839618 ! BMP signaling pathway GO:0030509 71 32 1,000 3,536E-03 0,03822629 ! hindbrain development GO:0030902 65 32 1,000 3,536E-03 0,03805789 ! cholesterol homeostasis GO:0042632 60 33 1,000 3,758E-03 0,04026337 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 3,758E-03 0,04008754 ! cholesterol transport GO:0030301 62 34 1,000 3,985E-03 0,04233195 ! formation of primary germ layer GO:0001704 76 34 1,000 3,985E-03 0,0421487 ! cell fate specification GO:0001708 56 34 1,000 3,985E-03 0,04196702 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 3,985E-03 0,0417869 ! serine family amino acid metabolic process GO:0009069 56 34 1,000 3,985E-03 0,04160833 ! mesoderm morphogenesis GO:0048332 80 35 1,000 4,219E-03 0,04386365 ! membrane docking GO:0022406 69 35 1,000 4,219E-03 0,04367779 ! sterol transport GO:0015918 63 35 1,000 4,219E-03 0,0434935 ! calcium-mediated signaling GO:0019722 67 35 1,000 4,219E-03 0,04331075 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 4,46E-03 0,04558489 ! tissue remodeling GO:0048771 78 37 1,000 4,706E-03 0,04790315 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 4,959E-03 0,0502646 ! neutral lipid metabolic process GO:0006638 54 38 1,000 4,959E-03 0,0500569 GO:0006639|acylglycerol metabolic process, ! glycogen metabolic process GO:0005977 63 38 1,000 4,959E-03 0,0498509 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 4,959E-03 0,04964659 ! erythrocyte homeostasis GO:0034101 75 39 1,000 5,217E-03 0,05202345 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 5,217E-03 0,05181198 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 5,217E-03 0,05160221 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 5,482E-03 0,05400242 ! lipid homeostasis GO:0055088 75 40 1,000 5,482E-03 0,05378554 ! glycerol ether metabolic process GO:0006662 57 40 1,000 5,482E-03 0,0535704 ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 5,753E-03 0,05599301 ! organic ether metabolic process GO:0018904 59 42 1,000 6,03E-03 0,05845476 ! T cell differentiation GO:0030217 93 42 1,000 6,03E-03 0,05822371 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 6,313E-03 0,06071487 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 6,313E-03 0,06047677 ! striated muscle cell differentiation GO:0051146 91 43 1,000 6,313E-03 0,06024053 ! segmentation GO:0035282 78 43 1,000 6,313E-03 0,06000613 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 6,313E-03 0,05977355 ! energy reserve metabolic process GO:0006112 76 44 1,000 6,601E-03 0,06226676 ! double-strand break repair GO:0006302 85 44 1,000 6,601E-03 0,06202727 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 6,896E-03 0,06454813 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 6,896E-03 0,06430176 ! keratinocyte differentiation GO:0030216 81 45 1,000 6,896E-03 0,06405727 ! biopolymer methylation GO:0043414 91 45 1,000 6,896E-03 0,06381463 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 7,197E-03 0,06634492 ! response to insulin stimulus GO:0032868 98 47 1,000 7,503E-03 0,0689099 ! positive regulation of cell cycle GO:0045787 96 48 1,000 7,815E-03 0,07150888 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 7,815E-03 0,07124206 ! positive regulation of DNA binding GO:0043388 83 48 1,000 7,815E-03 0,07097722 ! JAK-STAT cascade GO:0007259 82 48 1,000 7,815E-03 0,07071434 ! methylation GO:0032259 97 48 1,000 7,815E-03 0,0704534 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 8,133E-03 0,07305085 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 8,457E-03 0,07568071 ! activation of caspase activity GO:0006919 95 50 1,000 8,457E-03 0,0754045 ! regulation of ossification GO:0030278 123 50 1,000 8,457E-03 0,0751303 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 8,457E-03 0,07485809 ! epidermal cell differentiation GO:0009913 87 50 1,000 8,457E-03 0,07458784 ! response to temperature stimulus GO:0009266 84 51 1,000 8,787E-03 0,07721509 ! positive regulation of binding GO:0051099 88 52 1,000 9,122E-03 0,07987324 ! histone modification GO:0016570 104 52 1,000 9,122E-03 0,07958798 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 9,122E-03 0,07930475 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 9,463E-03 0,08197614 ! vesicle organization GO:0016050 127 53 1,000 9,463E-03 0,08168647 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 9,463E-03 0,08139884 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! activation of phospholipase C activity GO:0007202 110 54 1,000 9,809E-03 0,0840829 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 1,000 9,809E-03 0,0837889 ! membrane fusion GO:0006944 122 54 1,000 9,809E-03 0,08349695 ! covalent chromatin modification GO:0016569 115 54 1,000 9,809E-03 0,08320703 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 9,809E-03 0,08291912 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01016112 0,08559868 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,01016112 0,08530452 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01088178 0,09104173 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,01088178 0,09073101 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,01088178 0,0904224 ! regulation of actin filament length GO:0030832 118 58 1,000 0,01125035 0,09316816 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,01125035 0,0928534 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01125035 0,09254076 ! gastrulation GO:0007369 122 58 1,000 0,01125035 0,09223023 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01125035 0,09192176 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,01125035 0,09161536 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01125035 0,09131099 ! lipid modification GO:0030258 112 60 1,000 0,01200382 0,09710372 ! kidney development GO:0001822 133 60 1,000 0,01200382 0,09678325 ! regulation of cellular component size GO:0032535 125 61 1,000 0,01238865 0,09955745 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,01238865 0,09923103 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,01277883 0,10202185 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,01357514 0,10802629 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,01357514 0,10767555 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,01357514 0,10732709 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01371069 0,10804907 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01371069 0,10770165 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01371069 0,10735645 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01371069 0,10701346 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01371069 0,10667265 ! neuron fate determination GO:0048664 7 5 0,000 0,01371069 0,10633401 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01371069 0,10599751 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01371069 0,10566313 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01371069 0,10533085 ! polyol transport GO:0015791 12 5 0,000 0,01371069 0,10500066 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01371069 0,10467254 ! response to superoxide GO:0000303 10 5 0,000 0,01371069 0,10434645 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01371069 0,1040224 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01371069 0,10370035 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01371069 0,10338028 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01371069 0,10306219 ! female meiosis GO:0007143 10 5 0,000 0,01371069 0,10274605 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01371069 0,10243184 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01371069 0,10211955 ! hypothalamus development GO:0021854 9 5 0,000 0,01371069 0,10180915 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01371069 0,10150064 ! cobalt ion transport GO:0006824 11 5 0,000 0,01371069 0,10119399 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01371069 0,10088919 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01371069 0,10058622 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01371069 0,10028506 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01371069 0,09998571 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01371069 0,09968813 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01371069 0,09939232 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01371069 0,09909826 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01371069 0,09880593 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01371069 0,09851533 ! transposition GO:0032196 9 5 0,000 0,01371069 0,09822643 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01371069 0,09793922 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01371069 0,09765368 ! negative chemotaxis GO:0050919 16 5 0,000 0,01371069 0,0973698 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01371069 0,09708757 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01371069 0,09680697 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01371069 0,09652799 ! behavioral response to pain GO:0048266 10 5 0,000 0,01371069 0,09625061 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01371069 0,09597482 ! Notch receptor processing GO:0007220 11 5 0,000 0,01371069 0,0957006 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01371069 0,09542795 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01371069 0,09515685 ! micturition GO:0060073 9 5 0,000 0,01371069 0,09488729 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01371069 0,09461924 ! copulation GO:0007620 9 5 0,000 0,01371069 0,09435271 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01371069 0,09408767 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01371069 0,09382412 ! bioluminescence GO:0008218 9 5 0,000 0,01371069 0,09356204 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01371069 0,09330143 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01371069 0,09304225 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01371069 0,09278452 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01371069 0,09252821 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01371069 0,09227331 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01371069 0,09201981 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01371069 0,0917677 ! grooming behavior GO:0007625 6 5 0,000 0,01371069 0,09151697 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01371069 0,09126761 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01371069 0,0910196 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01371069 0,09077293 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01371069 0,0905276 ! response to protozoan GO:0001562 13 5 0,000 0,01371069 0,09028359 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01371069 0,09004089 ! lymph vessel development GO:0001945 10 5 0,000 0,01371069 0,0897995 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01371069 0,08955939 ! endochondral ossification GO:0001958 17 5 0,000 0,01371069 0,08932056 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01371069 0,08908301 ! single strand break repair GO:0000012 8 5 0,000 0,01371069 0,08884672 ! parathyroid gland development GO:0060017 14 5 0,000 0,01371069 0,08861167 ! anagen GO:0042640 7 5 0,000 0,01371069 0,08837787 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01371069 0,08814529 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01371069 0,08791394 ! cytokine secretion GO:0050663 15 5 0,000 0,01371069 0,0876838 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01371069 0,08745486 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01371069 0,08722711 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01371069 0,08700055 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01371069 0,08677516 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01371069 0,08655093 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01371069 0,08632787 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01371069 0,08610594 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01371069 0,08588516 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01371069 0,0856655 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01371069 0,08544697 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01371069 0,08522955 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01371069 0,08501323 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01371069 0,084798 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01371069 0,08458387 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01371069 0,08437081 ! valine metabolic process GO:0006573 12 5 0,000 0,01371069 0,08415882 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01371069 0,0839479 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01371069 0,08373803 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01371069 0,08352921 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01371069 0,08332142 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01371069 0,08311467 ! polyol catabolic process GO:0046174 9 5 0,000 0,01371069 0,08290894 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01371069 0,08270423 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01371069 0,08250052 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01371069 0,08229782 ! muscle cell migration GO:0014812 8 5 0,000 0,01371069 0,08209611 ! mitochondrial fission GO:0000266 8 5 0,000 0,01371069 0,08189538 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01371069 0,08169564 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01371069 0,08149687 ! mRNA transcription GO:0009299 10 5 0,000 0,01371069 0,08129906 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01371069 0,08110221 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01371069 0,08090631 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01371069 0,08071135 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01371069 0,08051734 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01371069 0,08032425 ! monocyte activation GO:0042117 10 5 0,000 0,01371069 0,08013209 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01371069 0,07994084 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01371069 0,0797505 ! response to food GO:0032094 6 5 0,000 0,01371069 0,07956107 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01371069 0,07937254 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01371069 0,0791849 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01371069 0,07899814 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01371069 0,07881226 ! forebrain neuron development GO:0021884 13 5 0,000 0,01371069 0,07862726 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01371069 0,07844312 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01371069 0,07825984 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01371069 0,07807742 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01371069 0,07789584 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01371069 0,07771511 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01371069 0,07753521 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01371069 0,07735615 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01371069 0,07717791 ! lipid glycosylation GO:0030259 7 5 0,000 0,01371069 0,07700049 ! nucleobase transport GO:0015851 6 5 0,000 0,01371069 0,07682388 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01371069 0,07664808 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01371069 0,07647309 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01371069 0,07629889 ! basic amino acid transport GO:0015802 12 5 0,000 0,01371069 0,07612548 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01371069 0,07595286 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01371069 0,07578102 ! actin nucleation GO:0045010 11 5 0,000 0,01371069 0,07560996 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01371069 0,07543967 ! depurination GO:0045007 5 5 0,000 0,01371069 0,07527014 ! depyrimidination GO:0045008 10 5 0,000 0,01371069 0,07510137 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01371069 0,07493336 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01371069 0,0747661 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01371069 0,07459958 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01371069 0,0744338 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01371069 0,07426876 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01371069 0,07410445 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01371069 0,07394086 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01371069 0,073778 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01371069 0,07361585 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01371069 0,07345441 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01371069 0,07329368 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01371069 0,07313365 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01371069 0,07297432 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01371069 0,07281568 ! response to arsenic GO:0046685 11 5 0,000 0,01371069 0,07265773 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01371069 0,07250046 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01371069 0,07234387 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01371069 0,07218796 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01371069 0,07203271 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01371069 0,07187814 ! response to mercury ion GO:0046689 8 5 0,000 0,01371069 0,07172422 ! response to cadmium ion GO:0046686 7 5 0,000 0,01371069 0,07157097 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01371069 0,07141836 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01371069 0,07126641 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01371069 0,0711151 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01371069 0,07096443 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01371069 0,0708144 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01371069 0,070665 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01371069 0,07051624 ! decidualization GO:0046697 11 5 0,000 0,01371069 0,07036809 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01371069 0,07022057 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01371069 0,07007366 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01371069 0,06992737 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01371069 0,06978169 ! embryonic cleavage GO:0040016 6 5 0,000 0,01371069 0,06963661 ! peroxisome fission GO:0016559 5 5 0,000 0,01371069 0,06949214 ! histone demethylation GO:0016577 13 5 0,000 0,01371069 0,06934826 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01371069 0,06920498 ! mitotic recombination GO:0006312 9 5 0,000 0,01371069 0,06906229 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01371069 0,06892019 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01371069 0,06877867 ! metaphase plate congression GO:0051310 7 5 0,000 0,01371069 0,06863773 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01371069 0,06849737 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01371069 0,06835757 ! enteric nervous system development GO:0048484 8 5 0,000 0,01371069 0,06821835 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01371069 0,0680797 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01371069 0,06794161 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01371069 0,06780407 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01371069 0,06766709 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01371069 0,06753067 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01371069 0,06739479 ! B cell homeostasis GO:0001782 13 5 0,000 0,01371069 0,06725946 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01371069 0,06712467 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01371069 0,06699042 ! metaphase GO:0051323 11 5 0,000 0,01371069 0,06685671 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01371069 0,06672353 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01371069 0,06659088 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01371069 0,06645875 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01371069 0,06632715 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01371069 0,06619607 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01371069 0,06606551 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01371069 0,06593546 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01371069 0,06580592 ! response to redox state GO:0051775 6 5 0,000 0,01371069 0,06567689 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01371069 0,06554836 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01371069 0,06542034 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01371069 0,06529281 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01371069 0,06516578 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01371069 0,06503925 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01371069 0,0649132 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01371069 0,06478764 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01371069 0,06466257 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01371069 0,06453798 ! striatum development GO:0021756 14 5 0,000 0,01371069 0,06441387 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01371069 0,06429023 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01371069 0,06416707 ! glial cell migration GO:0008347 10 5 0,000 0,01371069 0,06404438 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01371069 0,06392216 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01371069 0,0638004 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01371069 0,06367911 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01371069 0,06355828 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01371069 0,0634379 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01371069 0,06331798 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01371069 0,06319851 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01371069 0,06307949 ! neuroprotection GO:0043526 8 5 0,000 0,01371069 0,06296092 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01371069 0,0628428 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01371069 0,06272512 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01371069 0,06260787 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01371069 0,06249107 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01371069 0,0623747 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01371069 0,06225876 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01371069 0,06214325 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01371069 0,06202817 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01371069 0,06191352 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01371069 0,06179928 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01371069 0,06168547 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01371069 0,06157208 ! spindle assembly GO:0051225 6 5 0,000 0,01371069 0,0614591 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01371069 0,06134654 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01371069 0,06123439 ! protein palmitoylation GO:0018345 12 5 0,000 0,01371069 0,06112265 ! drug metabolic process GO:0017144 7 5 0,000 0,01371069 0,06101131 ! stem cell division GO:0017145 11 5 0,000 0,01371069 0,06090038 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01371069 0,06078986 ! organ regeneration GO:0031100 7 5 0,000 0,01371069 0,06067973 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01371069 0,06057 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01371069 0,06046067 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,0139812 0,06154248 ! chromosome segregation GO:0007059 127 67 1,000 0,01480898 0,06506895 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,01480898 0,06495213 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,01523063 0,06668178 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01523063 0,06656249 ! cell projection assembly GO:0030031 138 68 1,000 0,01523063 0,06644363 ! urogenital system development GO:0001655 149 69 1,000 0,01565742 0,06818374 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,01565742 0,06806242 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,01565742 0,06794153 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,01565742 0,06782106 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01643041 0,07104337 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01643041 0,07091785 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01643041 0,07079277 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01643041 0,07066814 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01643041 0,07054394 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01643041 0,07042018 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01643041 0,07029685 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01643041 0,07017396 ! response to oxygen radical GO:0000305 11 6 0,000 0,01643041 0,07005149 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01643041 0,06992945 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01643041 0,06980783 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01643041 0,06968664 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01643041 0,06956586 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01643041 0,06944551 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01643041 0,06932557 ! forebrain regionalization GO:0021871 9 6 0,000 0,01643041 0,06920604 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01643041 0,06908692 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01643041 0,06896822 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01643041 0,06884992 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01643041 0,06873203 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01643041 0,06861454 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01643041 0,06849745 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01643041 0,06838075 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01643041 0,06826446 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01643041 0,06814856 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01643041 0,06803306 ! malate metabolic process GO:0006108 13 6 0,000 0,01643041 0,06791794 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01643041 0,06780321 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01643041 0,06768888 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01643041 0,06757492 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01643041 0,06746135 ! protein refolding GO:0042026 15 6 0,000 0,01643041 0,06734816 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01643041 0,06723535 ! opsonization GO:0008228 8 6 0,000 0,01643041 0,06712291 ! mating behavior GO:0007617 7 6 0,000 0,01643041 0,06701086 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01643041 0,06689917 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01643041 0,06678786 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01643041 0,06667692 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01643041 0,06656634 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01643041 0,06645613 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01643041 0,06634629 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01643041 0,0662368 ! toxin metabolic process GO:0009404 11 6 0,000 0,01643041 0,06612768 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01643041 0,06601892 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01643041 0,06591051 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01643041 0,06580246 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01643041 0,06569477 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01643041 0,06558742 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01643041 0,06548043 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01643041 0,06537378 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01643041 0,06526748 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01643041 0,06516153 ! thymic T cell selection GO:0045061 16 6 0,000 0,01643041 0,06505592 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01643041 0,06495065 ! protein lipoylation GO:0009249 10 6 0,000 0,01643041 0,06484572 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01643041 0,06474113 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01643041 0,06463688 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01643041 0,06453296 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01643041 0,06442938 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01643041 0,06432613 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01643041 0,0642232 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01643041 0,06412061 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01643041 0,06401835 ! hyperosmotic response GO:0006972 10 6 0,000 0,01643041 0,06391641 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01643041 0,06381479 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01643041 0,0637135 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01643041 0,06361252 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01643041 0,06351187 ! urea metabolic process GO:0019627 7 6 0,000 0,01643041 0,06341154 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01643041 0,06331152 ! neutrophil activation GO:0042119 7 6 0,000 0,01643041 0,06321182 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01643041 0,06311243 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01643041 0,06301335 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01643041 0,06291458 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01643041 0,06281612 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01643041 0,06271797 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01643041 0,06262013 ! neuron apoptosis GO:0051402 15 6 0,000 0,01643041 0,06252259 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01643041 0,06242535 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01643041 0,06232842 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01643041 0,06223179 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01643041 0,06213545 ! carnitine transport GO:0015879 10 6 0,000 0,01643041 0,06203942 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01643041 0,06194368 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01643041 0,06184823 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01643041 0,06175308 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01643041 0,06165822 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01643041 0,06156365 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01643041 0,06146938 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01643041 0,06137539 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01643041 0,06128168 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01643041 0,06118827 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01643041 0,06109513 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01643041 0,06100228 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01643041 0,06090972 ! response to UV-C GO:0010225 14 6 0,000 0,01643041 0,06081743 ! astrocyte development GO:0014002 16 6 0,000 0,01643041 0,06072542 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01643041 0,06063369 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01643041 0,06054224 ! interaction with symbiont GO:0051702 14 6 0,000 0,01643041 0,06045106 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01643041 0,06036015 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01643041 0,06026952 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01643041 0,06017916 ! response to copper ion GO:0046688 10 6 0,000 0,01643041 0,06008908 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01643041 0,05999926 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01643041 0,05990971 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01643041 0,05982042 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01643041 0,0597314 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01643041 0,05964265 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01643041 0,05955416 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01643041 0,05946593 ! hair follicle maturation GO:0048820 8 6 0,000 0,01643041 0,05937796 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01643041 0,05929026 ! Schwann cell development GO:0014044 15 6 0,000 0,01643041 0,05920281 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01643041 0,05911562 ! response to pheromone GO:0019236 6 6 0,000 0,01643041 0,05902868 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01643041 0,058942 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01643041 0,05885558 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01643041 0,0587694 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01643041 0,05868348 ! subpallium development GO:0021544 15 6 0,000 0,01643041 0,05859781 ! neural tube patterning GO:0021532 8 6 0,000 0,01643041 0,0585124 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01643041 0,05842722 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01643041 0,0583423 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01643041 0,05825762 ! G2 phase GO:0051319 16 6 0,000 0,01643041 0,05817319 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01643041 0,05808901 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01643041 0,05800506 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01643041 0,05792136 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01643041 0,0578379 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01643041 0,05775468 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01643041 0,0576717 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01643041 0,05758896 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01643041 0,05750645 ! receptor internalization GO:0031623 11 6 0,000 0,01643041 0,05742418 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01643041 0,05734215 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01643041 0,05726035 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01643041 0,05717878 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01643041 0,05709744 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01643041 0,05701634 ! protein deubiquitination GO:0016579 16 6 0,000 0,01643041 0,05693547 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01643041 0,05685482 ! protein destabilization GO:0031648 9 6 0,000 0,01643041 0,0567744 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01643041 0,05669421 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01643041 0,05661425 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01643041 0,05653451 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01643041 0,056455 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01643041 0,05637571 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01643041 0,05629664 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01643041 0,05621779 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01643041 0,05613917 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01643041 0,05606076 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01643041 0,05598257 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01643041 0,0559046 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01643041 0,05582685 ! neural plate development GO:0001840 9 6 0,000 0,01643041 0,05574931 ! catecholamine transport GO:0051937 9 6 0,000 0,01643041 0,05567199 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01643041 0,05559488 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01643041 0,05551798 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01643041 0,0554413 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01643041 0,05536483 ! maternal placenta development GO:0001893 12 6 0,000 0,01643041 0,05528857 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01643041 0,05521252 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01643041 0,05513668 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01643041 0,05506105 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01643041 0,05498562 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01643041 0,0549104 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01643041 0,05483539 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01643041 0,05476058 GO:0055081|anion homeostasis, ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,01696829 0,0564762 ! humoral immune response GO:0006959 115 73 1,000 0,01741531 0,05788518 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01832427 0,06082364 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 1,000 0,01832427 0,06074111 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,01878615 0,06218775 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,01878615 0,0621036 ! learning or memory GO:0007611 161 76 1,000 0,01878615 0,06201968 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,01878615 0,06193598 ! tRNA transcription GO:0009304 17 7 0,000 0,01914272 0,06302649 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01914272 0,06294167 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01914272 0,06285707 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01914272 0,0627727 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01914272 0,06268855 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01914272 0,06260463 ! sleep GO:0030431 16 7 0,000 0,01914272 0,06252093 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01914272 0,06243746 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01914272 0,06235421 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01914272 0,06227118 ! prostate gland development GO:0030850 14 7 0,000 0,01914272 0,06218838 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01914272 0,06210579 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01914272 0,06202342 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01914272 0,06194127 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01914272 0,06185934 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01914272 0,06177762 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01914272 0,06169612 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01914272 0,06161483 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01914272 0,06153376 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01914272 0,0614529 ! glycolipid transport GO:0046836 11 7 0,000 0,01914272 0,06137226 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01914272 0,06129182 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01914272 0,0612116 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01914272 0,06113158 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01914272 0,06105177 ! mRNA stabilization GO:0048255 18 7 0,000 0,01914272 0,06097218 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01914272 0,06089279 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01914272 0,0608136 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01914272 0,06073462 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01914272 0,06065585 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01914272 0,06057728 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01914272 0,06049891 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01914272 0,06042075 ! lipoprotein transport GO:0042953 14 7 0,000 0,01914272 0,06034279 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01914272 0,06026502 ! rhythmic behavior GO:0007622 17 7 0,000 0,01914272 0,06018746 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01914272 0,0601101 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01914272 0,06003294 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01914272 0,05995597 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01914272 0,0598792 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01914272 0,05980263 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01914272 0,05972626 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01914272 0,05965008 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01914272 0,05957409 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01914272 0,05949829 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01914272 0,05942269 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01914272 0,05934728 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01914272 0,05927206 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01914272 0,05919704 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01914272 0,0591222 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01914272 0,05904755 ! spinal cord patterning GO:0021511 14 7 0,000 0,01914272 0,05897309 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01914272 0,05889881 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01914272 0,05882473 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01914272 0,05875083 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01914272 0,05867711 ! adrenal gland development GO:0030325 17 7 0,000 0,01914272 0,05860358 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01914272 0,05853024 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01914272 0,05845707 ! ovulation GO:0030728 10 7 0,000 0,01914272 0,05838409 ! adenohypophysis development GO:0021984 11 7 0,000 0,01914272 0,0583113 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01914272 0,05823868 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01914272 0,05816624 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01914272 0,05809399 ! microtubule nucleation GO:0007020 21 7 0,000 0,01914272 0,05802191 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01914272 0,05795001 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01914272 0,05787829 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01914272 0,05780675 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01914272 0,05773538 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01914272 0,05766419 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01914272 0,05759318 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01914272 0,05752234 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01914272 0,05745167 ! galactose metabolic process GO:0006012 13 7 0,000 0,01914272 0,05738118 ! response to dietary excess GO:0002021 8 7 0,000 0,01914272 0,05731086 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01914272 0,05724071 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01914272 0,05717073 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01914272 0,05710093 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01914272 0,05703129 ! organ growth GO:0035265 15 7 0,000 0,01914272 0,05696183 ! nucleoside transport GO:0015858 11 7 0,000 0,01914272 0,05689253 ! nucleoside salvage GO:0043174 11 7 0,000 0,01914272 0,0568234 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01914272 0,05675444 ! male sex determination GO:0030238 15 7 0,000 0,01914272 0,05668565 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01914272 0,05661702 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01914272 0,05654856 ! parturition GO:0007567 16 7 0,000 0,01914272 0,05648026 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01914272 0,05641213 ! rRNA modification GO:0000154 14 7 0,000 0,01914272 0,05634417 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01914272 0,05627636 ! spindle checkpoint GO:0031577 16 7 0,000 0,01914272 0,05620872 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01914272 0,05614125 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01914272 0,05607393 ! monocyte differentiation GO:0030224 16 7 0,000 0,01914272 0,05600678 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01914272 0,05593978 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01914272 0,05587295 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01914272 0,05580628 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01914272 0,05573976 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01914272 0,0556734 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01914272 0,0556072 ! fibrinolysis GO:0042730 11 7 0,000 0,01914272 0,05554116 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01914272 0,05547528 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01914272 0,05540955 ! eating behavior GO:0042755 8 7 0,000 0,01914272 0,05534398 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01914272 0,05527856 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01914272 0,05521329 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01914272 0,05514818 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01914272 0,05508323 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01914272 0,05501842 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01914272 0,05495377 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01914272 0,05488927 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01914272 0,05482492 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01914272 0,05476072 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01914272 0,05469668 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01914272 0,05463278 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01914272 0,05456903 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01914272 0,05450543 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01914272 0,05444198 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01914272 0,05437867 ! histone ubiquitination GO:0016574 9 7 0,000 0,01914272 0,05431552 ! regulation of meiosis GO:0040020 12 7 0,000 0,01914272 0,0542525 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01914272 0,05418964 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01914272 0,05412692 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01914272 0,05406435 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01914272 0,05400192 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01914272 0,05393963 ! transcription termination GO:0006353 14 7 0,000 0,01914272 0,05387749 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01914272 0,05381549 ! anaphase GO:0051322 18 7 0,000 0,01914272 0,05375363 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01914272 0,05369192 ! axonal fasciculation GO:0007413 19 7 0,000 0,01914272 0,05363034 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01914272 0,05356891 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01914272 0,05350762 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01914272 0,05344647 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01914272 0,05338546 ! diuresis GO:0030146 12 7 0,000 0,01914272 0,05332458 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01914272 0,05326385 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01914272 0,05320325 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01914272 0,05314279 ! antibiotic transport GO:0042891 9 7 0,000 0,01914272 0,05308247 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01914272 0,05302229 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01914272 0,05296224 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01914272 0,05290233 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01914272 0,05284255 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01914272 0,05278291 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01914272 0,0527234 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01914272 0,05266403 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01914272 0,05260479 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01914272 0,05254568 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01914272 0,05248671 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01914272 0,05242787 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01914272 0,05236916 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01914272 0,05231058 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01914272 0,05225213 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01914272 0,05219382 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01914272 0,05213563 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01914272 0,05207757 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01914272 0,05201964 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01914272 0,05196184 ! muscle adaptation GO:0043500 13 7 0,000 0,01914272 0,05190417 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01914272 0,05184663 ! retina homeostasis GO:0001895 12 7 0,000 0,01914272 0,05178921 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01914272 0,05173192 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01914272 0,05167476 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01914272 0,05161773 ! amine catabolic process GO:0009310 136 77 1,000 0,01925292 0,05185764 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01925292 0,05180053 ! antigen processing and presentation GO:0019882 117 78 1,000 0,01972455 0,05301108 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01972455 0,05295283 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,02020101 0,05417241 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,02068228 0,05540219 ! meiosis GO:0007126 143 81 1,000 0,02116831 0,05664205 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,02116831 0,05658007 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,02165909 0,0578286 ! protein import into nucleus GO:0006606 174 82 1,000 0,02165909 0,05776546 ! meiotic cell cycle GO:0051321 144 82 1,000 0,02165909 0,05770247 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02184762 0,05814132 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02184762 0,05807805 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02184762 0,05801492 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02184762 0,05795193 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02184762 0,05788908 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02184762 0,05782636 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02184762 0,05776378 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02184762 0,05770133 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02184762 0,05763902 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02184762 0,05757684 ! meiotic prophase I GO:0007128 14 8 0,000 0,02184762 0,05751479 ! response to zinc ion GO:0010043 12 8 0,000 0,02184762 0,05745288 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02184762 0,05739111 ! oligopeptide transport GO:0006857 16 8 0,000 0,02184762 0,05732946 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02184762 0,05726795 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02184762 0,05720657 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02184762 0,05714532 ! signal peptide processing GO:0006465 12 8 0,000 0,02184762 0,0570842 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02184762 0,05702321 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02184762 0,05696236 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02184762 0,05690163 ! succinate metabolic process GO:0006105 17 8 0,000 0,02184762 0,05684103 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02184762 0,05678056 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02184762 0,05672022 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02184762 0,05666001 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02184762 0,05659992 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02184762 0,05653997 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02184762 0,05648014 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02184762 0,05642043 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02184762 0,05636085 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02184762 0,0563014 ! reflex GO:0060004 17 8 0,000 0,02184762 0,05624207 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02184762 0,05618287 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02184762 0,05612379 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02184762 0,05606484 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02184762 0,05600601 ! pigment granule organization GO:0048753 17 8 0,000 0,02184762 0,0559473 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02184762 0,05588872 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02184762 0,05583026 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02184762 0,05577192 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02184762 0,0557137 ! histidine catabolic process GO:0006548 10 8 0,000 0,02184762 0,05565561 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02184762 0,05559763 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02184762 0,05553978 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02184762 0,05548205 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02184762 0,05542443 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02184762 0,05536694 ! melanin metabolic process GO:0006582 17 8 0,000 0,02184762 0,05530956 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02184762 0,05525231 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02184762 0,05519517 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02184762 0,05513815 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02184762 0,05508125 ! macrophage activation GO:0042116 13 8 0,000 0,02184762 0,05502446 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02184762 0,05496779 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02184762 0,05491124 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02184762 0,05485481 ! purine salvage GO:0043101 12 8 0,000 0,02184762 0,05479849 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02184762 0,05474229 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02184762 0,0546862 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02184762 0,05463022 ! osteoblast development GO:0002076 17 8 0,000 0,02184762 0,05457436 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02184762 0,05451862 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02184762 0,05446299 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02184762 0,05440747 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02184762 0,05435207 ! response to UV-B GO:0010224 17 8 0,000 0,02184762 0,05429677 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02184762 0,05424159 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02184762 0,05418653 ! intermediate filament organization GO:0045109 12 8 0,000 0,02184762 0,05413157 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02184762 0,05407673 ! cellular extravasation GO:0045123 13 8 0,000 0,02184762 0,05402199 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02184762 0,05396737 ! response to antibiotic GO:0046677 11 8 0,000 0,02184762 0,05391286 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02184762 0,05385845 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02184762 0,05380416 ! DNA topological change GO:0006265 12 8 0,000 0,02184762 0,05374998 ! response to tropane GO:0014073 15 8 0,000 0,02184762 0,0536959 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02184762 0,05364194 ! melanosome transport GO:0032402 13 8 0,000 0,02184762 0,05358808 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02184762 0,05353433 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02184762 0,05348069 ! mast cell activation GO:0045576 14 8 0,000 0,02184762 0,05342716 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02184762 0,05337373 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02184762 0,05332041 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02184762 0,05326719 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02184762 0,05321409 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02184762 0,05316108 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02184762 0,05310819 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02184762 0,0530554 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02184762 0,05300271 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02184762 0,05295013 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02184762 0,05289765 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02184762 0,05284528 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02184762 0,05279301 ! response to tumor cell GO:0002347 16 8 0,000 0,02184762 0,05274084 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02184762 0,05268877 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,02184762 0,05263681 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02184762 0,05258495 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02184762 0,0525332 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02184762 0,05248154 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02184762 0,05242999 ! hormone catabolic process GO:0042447 17 8 0,000 0,02184762 0,05237854 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02184762 0,05232718 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02184762 0,05227593 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02184762 0,05222478 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02184762 0,05217373 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02184762 0,05212278 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02184762 0,05207193 ! adult feeding behavior GO:0008343 10 8 0,000 0,02184762 0,05202118 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02184762 0,05197052 ! ATP catabolic process GO:0006200 11 8 0,000 0,02184762 0,05191997 ! blastocyst growth GO:0001832 19 8 0,000 0,02184762 0,05186951 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02184762 0,05181915 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02184762 0,05176889 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02184762 0,05171873 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02184762 0,05166866 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02184762 0,05161869 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02184762 0,05156882 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02184762 0,05151904 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02184762 0,05146936 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02184762 0,05141978 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02184762 0,05137029 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02184762 0,05132089 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02184762 0,05127159 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02184762 0,05122239 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02184762 0,05117328 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02184762 0,05112426 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02184762 0,05107534 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02184762 0,05102651 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02184762 0,05097777 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,02215459 0,05164471 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,02215459 0,05159548 ! T cell activation GO:0042110 189 84 1,000 0,02265477 0,05271009 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,02366906 0,05501763 GO:0002696|positive regulation of leukocyte activation, ! nucleosome assembly GO:0006334 126 87 1,000 0,02418313 0,0561591 ! axon extension GO:0048675 16 9 0,000 0,02454513 0,05694564 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02454513 0,05689161 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02454513 0,05683769 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02454513 0,05678386 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02454513 0,05673014 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02454513 0,05667652 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02454513 0,056623 ! reproductive behavior GO:0019098 22 9 0,000 0,02454513 0,05656959 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02454513 0,05651627 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02454513 0,05646305 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02454513 0,05640993 ! UTP metabolic process GO:0046051 10 9 0,000 0,02454513 0,05635692 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02454513 0,056304 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02454513 0,05625118 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02454513 0,05619846 ! artery development GO:0060840 25 9 0,000 0,02454513 0,05614584 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02454513 0,05609332 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02454513 0,0560409 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02454513 0,05598857 ! equilibrioception GO:0050957 20 9 0,000 0,02454513 0,05593634 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02454513 0,05588421 ! chemosensory behavior GO:0007635 21 9 0,000 0,02454513 0,05583218 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02454513 0,05578024 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02454513 0,0557284 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02454513 0,05567666 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02454513 0,05562501 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02454513 0,05557346 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02454513 0,055522 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02454513 0,05547064 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02454513 0,05541937 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02454513 0,0553682 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02454513 0,05531712 ! protein targeting to ER GO:0045047 25 9 0,000 0,02454513 0,05526614 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02454513 0,05521525 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02454513 0,05516445 ! T cell selection GO:0045058 27 9 0,000 0,02454513 0,05511375 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02454513 0,05506314 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02454513 0,05501262 ! endosome organization GO:0007032 20 9 0,000 0,02454513 0,0549622 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02454513 0,05491187 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02454513 0,05486163 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02454513 0,05481148 ! mannose metabolic process GO:0006013 13 9 0,000 0,02454513 0,05476142 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02454513 0,05471146 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02454513 0,05466159 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02454513 0,0546118 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02454513 0,05456211 ! receptor clustering GO:0043113 20 9 0,000 0,02454513 0,05451251 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02454513 0,054463 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02454513 0,05441358 ! retinol metabolic process GO:0042572 20 9 0,000 0,02454513 0,05436424 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02454513 0,054315 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02454513 0,05426585 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02454513 0,05421678 ! macrophage differentiation GO:0030225 15 9 0,000 0,02454513 0,05416781 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02454513 0,05411892 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02454513 0,05407012 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02454513 0,05402141 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02454513 0,05397278 ! response to amine stimulus GO:0014075 13 9 0,000 0,02454513 0,05392424 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02454513 0,0538758 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02454513 0,05382743 ! erythrocyte development GO:0048821 17 9 0,000 0,02454513 0,05377916 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02454513 0,05373097 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02454513 0,05368287 ! renal water homeostasis GO:0003091 15 9 0,000 0,02454513 0,05363485 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02454513 0,05358692 ! icosanoid secretion GO:0032309 15 9 0,000 0,02454513 0,05353907 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02454513 0,05349131 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02454513 0,05344364 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02454513 0,05339605 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02454513 0,05334854 ! sterol catabolic process GO:0016127 14 9 0,000 0,02454513 0,05330112 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02454513 0,05325378 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02454513 0,05320653 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02454513 0,05315936 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02454513 0,05311228 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02454513 0,05306527 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02454513 0,05301836 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02454513 0,05297152 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02454513 0,05292477 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02454513 0,0528781 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02454513 0,05283151 ! purine base metabolic process GO:0006144 25 9 0,000 0,02454513 0,052785 ! pigment granule transport GO:0051904 17 9 0,000 0,02454513 0,05273858 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02454513 0,05269223 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02454513 0,05264597 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02454513 0,05259979 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02454513 0,05255369 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02454513 0,05250767 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02454513 0,05246173 ! mitochondrion localization GO:0051646 18 9 0,000 0,02454513 0,05241587 ! chromatin assembly GO:0031497 128 88 1,000 0,02470175 0,05270427 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,02470175 0,05265828 ! regulation of DNA binding GO:0051101 167 89 1,000 0,02522493 0,05372667 ! tube morphogenesis GO:0035239 194 89 1,000 0,02522493 0,05367987 ! protein localization in nucleus GO:0034504 192 89 1,000 0,02522493 0,05363315 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,02575261 0,0547075 ! response to unfolded protein GO:0006986 139 90 1,000 0,02575261 0,05465997 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,02575261 0,05461252 ! gland development GO:0048732 220 91 1,000 0,02628478 0,05569272 ! defense response to bacterium GO:0042742 112 91 1,000 0,02628478 0,05564446 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,0268214 0,05673132 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,0268214 0,05668225 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02723529 0,05750718 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02723529 0,05745752 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02723529 0,05740794 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02723529 0,05735845 ! associative learning GO:0008306 21 10 0,000 0,02723529 0,05730905 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02723529 0,05725973 ! phosphate transport GO:0006817 24 10 0,000 0,02723529 0,05721049 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02723529 0,05716134 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02723529 0,05711228 ! CTP metabolic process GO:0046036 11 10 0,000 0,02723529 0,0570633 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02723529 0,0570144 ! GTP metabolic process GO:0046039 11 10 0,000 0,02723529 0,05696559 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02723529 0,05691685 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02723529 0,05686821 ! social behavior GO:0035176 29 10 0,000 0,02723529 0,05681964 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02723529 0,05677116 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02723529 0,05672277 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02723529 0,05667445 ! androgen metabolic process GO:0008209 17 10 0,000 0,02723529 0,05662622 ! phospholipid efflux GO:0033700 19 10 0,000 0,02723529 0,05657806 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02723529 0,05652999 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02723529 0,05648201 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02723529 0,0564341 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02723529 0,05638627 ! lung alveolus development GO:0048286 26 10 0,000 0,02723529 0,05633853 ! pathogenesis GO:0009405 17 10 0,000 0,02723529 0,05629087 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02723529 0,05624328 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02723529 0,05619578 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02723529 0,05614836 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02723529 0,05610101 ! endoderm development GO:0007492 18 10 0,000 0,02723529 0,05605375 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02723529 0,05600657 ! arginine catabolic process GO:0006527 17 10 0,000 0,02723529 0,05595946 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02723529 0,05591244 ! proline metabolic process GO:0006560 13 10 0,000 0,02723529 0,05586549 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02723529 0,05581863 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02723529 0,05577184 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02723529 0,05572513 ! V(D)J recombination GO:0033151 34 10 0,000 0,02723529 0,0556785 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02723529 0,05563194 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02723529 0,05558547 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02723529 0,05553907 ! B cell proliferation GO:0042100 19 10 0,000 0,02723529 0,05549275 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02723529 0,0554465 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02723529 0,05540034 ! multicellular organism growth GO:0035264 19 10 0,000 0,02723529 0,05535425 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02723529 0,05530823 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02723529 0,0552623 ! ruffle organization GO:0031529 17 10 0,000 0,02723529 0,05521643 ! epithelial cell development GO:0002064 21 10 0,000 0,02723529 0,05517065 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02723529 0,05512494 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02723529 0,05507931 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02723529 0,05503375 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02723529 0,05498827 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02723529 0,05494286 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02723529 0,05489753 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02723529 0,05485227 ! motor axon guidance GO:0008045 22 10 0,000 0,02723529 0,05480709 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02723529 0,05476198 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02723529 0,05471694 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02723529 0,05467198 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02723529 0,0546271 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02723529 0,05458228 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02723529 0,05453754 ! segment specification GO:0007379 15 10 0,000 0,02723529 0,05449288 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02723529 0,05444828 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02723529 0,05440376 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02723529 0,05435932 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02723529 0,05431494 ! response to dsRNA GO:0043331 23 10 0,000 0,02723529 0,05427064 ! DNA ligation GO:0006266 18 10 0,000 0,02723529 0,05422641 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02723529 0,05418225 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02723529 0,05413816 ! melanosome localization GO:0032400 16 10 0,000 0,02723529 0,05409415 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02723529 0,05405021 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02723529 0,05400633 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02723529 0,05396253 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02723529 0,0539188 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02723529 0,05387514 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02723529 0,05383156 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02723529 0,05378804 ! protein sumoylation GO:0016925 17 10 0,000 0,02723529 0,05374459 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02723529 0,05370121 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02723529 0,05365791 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02723529 0,05361467 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02723529 0,0535715 ! salivary gland development GO:0007431 28 10 0,000 0,02723529 0,0535284 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02723529 0,05348537 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02723529 0,05344241 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02723529 0,05339952 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02723529 0,0533567 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02723529 0,05331395 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02723529 0,05327126 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02723529 0,05322864 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02723529 0,05318609 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02723529 0,05314361 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02723529 0,0531012 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02723529 0,05305885 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02723529 0,05301658 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02723529 0,05297437 ! blastocyst formation GO:0001825 18 10 0,000 0,02723529 0,05293222 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02723529 0,05289015 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02723529 0,05284814 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02723529 0,05280619 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02723529 0,05276432 ! response to nicotine GO:0035094 20 10 0,000 0,02723529 0,05272251 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02723529 0,05268076 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02723529 0,05263908 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,02736245 0,05284306 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,0279079 0,05385387 ! regulation of membrane potential GO:0042391 179 94 1,000 0,0279079 0,05381137 ! nucleosome organization GO:0034728 143 95 1,000 0,02845772 0,05482825 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,02845772 0,05478504 ! response to protein stimulus GO:0051789 158 96 1,000 0,02901189 0,05580791 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,02957038 0,05683747 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0299181 0,05746062 ! respiratory burst GO:0045730 17 11 0,000 0,0299181 0,05741548 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0299181 0,05737041 ! neuron fate specification GO:0048665 18 11 0,000 0,0299181 0,05732542 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0299181 0,05728049 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0299181 0,05723564 ! thyroid gland development GO:0030878 26 11 0,000 0,0299181 0,05719085 ! synapsis GO:0007129 14 11 0,000 0,0299181 0,05714613 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0299181 0,05710149 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0299181 0,05705691 ! response to pain GO:0048265 27 11 0,000 0,0299181 0,05701241 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0299181 0,05696797 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0299181 0,0569236 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0299181 0,0568793 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,0299181 0,05683507 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,0299181 0,05679091 ! bone resorption GO:0045453 16 11 0,000 0,0299181 0,05674682 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0299181 0,0567028 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0299181 0,05665884 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0299181 0,05661495 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0299181 0,05657113 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0299181 0,05652738 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0299181 0,0564837 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0299181 0,05644008 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0299181 0,05639653 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,0299181 0,05635305 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0299181 0,05630964 ! UV protection GO:0009650 20 11 0,000 0,0299181 0,05626629 ! adult heart development GO:0007512 16 11 0,000 0,0299181 0,056223 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0299181 0,05617979 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0299181 0,05613664 ! macroautophagy GO:0016236 19 11 0,000 0,0299181 0,05609356 ! temperature homeostasis GO:0001659 18 11 0,000 0,0299181 0,05605054 ! behavioral fear response GO:0001662 27 11 0,000 0,0299181 0,05600759 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0299181 0,05596471 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0299181 0,05592189 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0299181 0,05587913 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0299181 0,05583644 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0299181 0,05579382 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0299181 0,05575126 ! regulation of organ growth GO:0046620 14 11 0,000 0,0299181 0,05570877 ! pigment granule localization GO:0051875 20 11 0,000 0,0299181 0,05566634 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0299181 0,05562398 ! vasoconstriction GO:0042310 20 11 0,000 0,0299181 0,05558168 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0299181 0,05553944 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0299181 0,05549727 ! embryonic axis specification GO:0000578 19 11 0,000 0,0299181 0,05545516 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0299181 0,05541312 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0299181 0,05537114 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0299181 0,05532923 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0299181 0,05528737 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0299181 0,05524558 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0299181 0,05520386 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0299181 0,05516219 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0299181 0,05512059 ! prophase GO:0051324 17 11 0,000 0,0299181 0,05507906 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0299181 0,05503758 ! nucleosome positioning GO:0016584 15 11 0,000 0,0299181 0,05499617 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0299181 0,05495482 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0299181 0,05491353 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0299181 0,0548723 ! apical protein localization GO:0045176 18 11 0,000 0,0299181 0,05483114 ! acid secretion GO:0046717 20 11 0,000 0,0299181 0,05479003 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0299181 0,05474899 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0299181 0,05470801 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,0299181 0,0546671 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0299181 0,05462624 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0299181 0,05458544 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0299181 0,05454471 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,0299181 0,05450403 ! cholesterol efflux GO:0033344 21 11 0,000 0,0299181 0,05446342 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0299181 0,05442286 ! oocyte development GO:0048599 20 11 0,000 0,0299181 0,05438237 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0299181 0,05434194 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0299181 0,05430156 ! embryonic gut development GO:0048566 19 11 0,000 0,0299181 0,05426125 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0299181 0,054221 ! activation of innate immune response GO:0002218 16 11 0,000 0,0299181 0,05418081 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0299181 0,05414067 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0299181 0,0541006 ! lysogeny GO:0030069 22 11 0,000 0,0299181 0,05406058 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0299181 0,05402063 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0299181 0,05398073 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0299181 0,05394089 ! nucleus localization GO:0051647 22 11 0,000 0,0299181 0,05390111 ! leukocyte differentiation GO:0002521 232 98 1,000 0,03013315 0,05424855 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03259358 0,05863484 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03259358 0,0585917 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,03259358 0,05854862 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03259358 0,0585056 ! virus-host interaction GO:0019048 30 12 0,000 0,03259358 0,05846264 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,03259358 0,05841975 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03259358 0,05837692 ! protein complex disassembly GO:0043241 28 12 0,000 0,03259358 0,05833415 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03259358 0,05829145 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,03259358 0,05824881 ! hippocampus development GO:0021766 29 12 0,000 0,03259358 0,05820623 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03259358 0,05816371 ! T cell proliferation GO:0042098 32 12 0,000 0,03259358 0,05812125 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03259358 0,05807886 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03259358 0,05803653 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03259358 0,05799426 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03259358 0,05795205 ! drug transport GO:0015893 16 12 0,000 0,03259358 0,0579099 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03259358 0,05786782 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03259358 0,05782579 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03259358 0,05778383 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03259358 0,05774193 ! focal adhesion formation GO:0048041 37 12 0,000 0,03259358 0,05770009 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03259358 0,0576583 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03259358 0,05761658 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03259358 0,05757492 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03259358 0,05753332 ! lipid digestion GO:0044241 21 12 0,000 0,03259358 0,05749178 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03259358 0,0574503 ! entry into host cell GO:0030260 34 12 0,000 0,03259358 0,05740888 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03259358 0,05736752 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03259358 0,05732622 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03259358 0,05728498 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03259358 0,05724379 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03259358 0,05720267 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03259358 0,05716161 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03259358 0,0571206 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03259358 0,05707965 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03259358 0,05703877 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03259358 0,05699794 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03259358 0,05695717 ! cranial nerve development GO:0021545 23 12 0,000 0,03259358 0,05691645 ! fucose catabolic process GO:0019317 25 12 0,000 0,03259358 0,0568758 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03259358 0,0568352 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03259358 0,05679466 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03259358 0,05675418 ! zymogen activation GO:0031638 18 12 0,000 0,03259358 0,05671376 ! T cell homeostasis GO:0043029 28 12 0,000 0,03259358 0,05667339 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03259358 0,05663308 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03259358 0,05659283 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,03259358 0,05655264 ! oocyte differentiation GO:0009994 21 12 0,000 0,03259358 0,0565125 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03259358 0,05647242 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03259358 0,0564324 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,03259358 0,05639243 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,03259358 0,05635252 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03259358 0,05631267 ! defense response to fungus GO:0050832 15 12 0,000 0,03259358 0,05627287 ! embryonic placenta development GO:0001892 21 12 0,000 0,03259358 0,05623313 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03259358 0,05619345 ! response to cold GO:0009409 17 12 0,000 0,03259358 0,05615382 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03259358 0,05611425 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03259358 0,05607473 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03526176 0,06062244 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03526176 0,06057981 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03526176 0,06053723 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03526176 0,06049472 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03526176 0,06045227 ! peroxisomal transport GO:0043574 28 13 0,000 0,03526176 0,06040988 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03526176 0,06036754 ! cartilage condensation GO:0001502 22 13 0,000 0,03526176 0,06032527 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03526176 0,06028305 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03526176 0,0602409 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03526176 0,0601988 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03526176 0,06015676 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03526176 0,06011478 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03526176 0,06007286 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03526176 0,060031 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03526176 0,0599892 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03526176 0,05994745 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03526176 0,05990576 ! methionine metabolic process GO:0006555 31 13 0,000 0,03526176 0,05986413 ! plasma membrane organization GO:0007009 27 13 0,000 0,03526176 0,05982256 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03526176 0,05978104 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03526176 0,05973959 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03526176 0,05969819 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03526176 0,05965685 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03526176 0,05961556 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03526176 0,05957433 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,03526176 0,05953316 ! exocrine system development GO:0035272 34 13 0,000 0,03526176 0,05949205 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03526176 0,05945099 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03526176 0,05940999 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03526176 0,05936905 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,03526176 0,05932816 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,03526176 0,05928733 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03526176 0,05924655 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03526176 0,05920583 ! protein homotetramerization GO:0051289 24 13 0,000 0,03526176 0,05916517 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03526176 0,05912456 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03526176 0,05908401 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03526176 0,05904351 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03526176 0,05900307 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03526176 0,05896269 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03526176 0,05892236 ! histone methylation GO:0016571 29 13 0,000 0,03526176 0,05888208 ! chromatin silencing GO:0006342 29 13 0,000 0,03526176 0,05884186 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03526176 0,0588017 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03526176 0,05876159 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03526176 0,05872153 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03526176 0,05868153 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03526176 0,05864158 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03526176 0,05860169 ! spleen development GO:0048536 24 13 0,000 0,03526176 0,05856185 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03526176 0,05852207 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03526176 0,05848234 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03526176 0,05844266 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03526176 0,05840304 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03526176 0,05836347 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03526176 0,05832396 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03526176 0,0582845 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03526176 0,05824509 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03526176 0,05820573 ! insulin secretion GO:0030073 24 13 0,000 0,03526176 0,05816643 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03526176 0,05812718 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03526176 0,05808799 ! acrosome reaction GO:0007340 19 13 0,000 0,03526176 0,05804884 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03526176 0,05800975 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03526176 0,05797072 ! rRNA transcription GO:0009303 28 14 0,000 0,03792266 0,06230333 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03792266 0,06226146 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03792266 0,06221965 ! water transport GO:0006833 21 14 0,000 0,03792266 0,06217789 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03792266 0,06213619 ! non-recombinational repair GO:0000726 29 14 0,000 0,03792266 0,06209454 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03792266 0,06205295 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03792266 0,06201142 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03792266 0,06196994 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03792266 0,06192851 ! palate development GO:0060021 32 14 0,000 0,03792266 0,06188715 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03792266 0,06184583 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03792266 0,06180457 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03792266 0,06176337 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03792266 0,06172222 ! arginine metabolic process GO:0006525 21 14 0,000 0,03792266 0,06168113 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03792266 0,06164009 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03792266 0,06159911 ! regulation of heart rate GO:0002027 25 14 0,000 0,03792266 0,06155818 ! fear response GO:0042596 34 14 0,000 0,03792266 0,0615173 ! organic alcohol transport GO:0015850 29 14 0,000 0,03792266 0,06147648 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03792266 0,06143571 ! embryo implantation GO:0007566 30 14 0,000 0,03792266 0,061395 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03792266 0,06135434 ! bone mineralization GO:0030282 18 14 0,000 0,03792266 0,06131374 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03792266 0,06127319 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03792266 0,06123269 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03792266 0,06119224 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03792266 0,06115185 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03792266 0,06111152 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03792266 0,06107123 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03792266 0,061031 ! ribosome assembly GO:0042255 18 14 0,000 0,03792266 0,06099082 ! cerebellum development GO:0021549 23 14 0,000 0,03792266 0,0609507 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03792266 0,06091062 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03792266 0,0608706 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03792266 0,06083064 ! response to gamma radiation GO:0010332 30 14 0,000 0,03792266 0,06079072 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03792266 0,06075086 ! NADP metabolic process GO:0006739 24 14 0,000 0,03792266 0,06071105 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03792266 0,06067129 ! oxygen transport GO:0015671 22 14 0,000 0,03792266 0,06063158 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03792266 0,06059193 ! male genitalia development GO:0030539 26 14 0,000 0,03792266 0,06055233 ! regulation of RNA stability GO:0043487 33 14 0,000 0,03792266 0,06051277 ! regulation of axon extension GO:0030516 43 14 0,000 0,03792266 0,06047328 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,03792266 0,06043383 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03792266 0,06039443 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04057629 0,06457843 ! lactation GO:0007595 30 15 0,000 0,04057629 0,06453638 ! reproductive cellular process GO:0048610 22 15 0,000 0,04057629 0,06449439 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04057629 0,06445246 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04057629 0,06441058 ! superoxide anion generation GO:0042554 22 15 0,000 0,04057629 0,06436876 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04057629 0,06432698 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,04057629 0,06428527 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04057629 0,06424361 ! copper ion transport GO:0006825 22 15 0,000 0,04057629 0,064202 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04057629 0,06416044 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04057629 0,06411894 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04057629 0,06407749 ! sulfate transport GO:0008272 27 15 0,000 0,04057629 0,0640361 ! response to cAMP GO:0051591 25 15 0,000 0,04057629 0,06399476 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04057629 0,06395347 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04057629 0,06391224 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,04057629 0,06387106 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04057629 0,06382993 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04057629 0,06378886 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04057629 0,06374783 ! vesicle coating GO:0006901 38 15 0,000 0,04057629 0,06370687 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,04057629 0,06366595 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,04057629 0,06362509 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,04057629 0,06358427 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04057629 0,06354351 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04057629 0,06350281 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,04057629 0,06346215 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04057629 0,06342155 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04057629 0,063381 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04057629 0,0633405 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04057629 0,06330005 ! histone deacetylation GO:0016575 24 15 0,000 0,04057629 0,06325966 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04057629 0,06321931 ! water homeostasis GO:0030104 28 15 0,000 0,04057629 0,06317902 ! cofactor transport GO:0051181 30 15 0,000 0,04057629 0,06313878 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04057629 0,06309859 ! muscle maintenance GO:0046716 26 15 0,000 0,04057629 0,06305845 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04057629 0,06301836 ! intestinal absorption GO:0050892 31 15 0,000 0,04057629 0,06297832 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04057629 0,06293834 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04057629 0,0628984 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04057629 0,06285852 ! cell killing GO:0001906 32 15 0,000 0,04057629 0,06281868 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04057629 0,0627789 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04057629 0,06273917 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04057629 0,06269948 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04057629 0,06265985 ! actin filament polymerization GO:0030041 27 15 0,000 0,04057629 0,06262027 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04057629 0,06258073 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04322268 0,06662019 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04322268 0,06657819 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04322268 0,06653624 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04322268 0,06649434 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04322268 0,06645249 ! bone remodeling GO:0046849 28 16 0,000 0,04322268 0,0664107 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04322268 0,06636896 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04322268 0,06632727 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04322268 0,06628563 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04322268 0,06624405 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04322268 0,06620251 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04322268 0,06616103 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04322268 0,0661196 ! startle response GO:0001964 28 16 0,000 0,04322268 0,06607823 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04322268 0,0660369 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04322268 0,06599563 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04322268 0,06595441 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04322268 0,06591324 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04322268 0,06587212 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04322268 0,06583105 ! pituitary gland development GO:0021983 30 16 0,000 0,04322268 0,06579004 ! response to osmotic stress GO:0006970 27 16 0,000 0,04322268 0,06574907 ! lysosomal transport GO:0007041 31 16 0,000 0,04322268 0,06570816 ! fructose metabolic process GO:0006000 25 16 0,000 0,04322268 0,06566729 ! L-amino acid transport GO:0015807 33 16 0,000 0,04322268 0,06562648 ! stem cell development GO:0048864 46 16 0,000 0,04322268 0,06558572 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04322268 0,06554501 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04322268 0,06550435 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04322268 0,06546374 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04322268 0,06542318 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04322268 0,06538267 ! axon cargo transport GO:0008088 46 16 0,000 0,04322268 0,06534221 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04322268 0,0653018 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04322268 0,06526144 ! DNA replication initiation GO:0006270 28 16 0,000 0,04322268 0,06522113 ! neuron recognition GO:0008038 40 16 0,000 0,04322268 0,06518087 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04322268 0,06514066 ! tissue regeneration GO:0042246 27 16 0,000 0,04322268 0,0651005 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04322268 0,06506039 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04322268 0,06502033 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04322268 0,06498031 ! biomineral formation GO:0031214 22 16 0,000 0,04322268 0,06494035 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04322268 0,06490044 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04322268 0,06486057 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04322268 0,06482075 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04322268 0,06478099 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04322268 0,06474127 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04322268 0,0647016 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04322268 0,06466198 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,04322268 0,0646224 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04322268 0,06458288 ! peptide hormone processing GO:0016486 27 16 0,000 0,04322268 0,0645434 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04586184 0,06844257 ! metencephalon development GO:0022037 32 17 0,000 0,04586184 0,06840078 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04586184 0,06835905 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04586184 0,06831737 ! signal complex assembly GO:0007172 47 17 0,000 0,04586184 0,06827574 ! filopodium assembly GO:0046847 42 17 0,000 0,04586184 0,06823416 ! endothelial cell migration GO:0043542 31 17 0,000 0,04586184 0,06819263 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04586184 0,06815115 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04586184 0,06810972 ! glial cell development GO:0021782 28 17 0,000 0,04586184 0,06806834 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04586184 0,06802701 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04586184 0,06798573 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04586184 0,0679445 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04586184 0,06790332 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,04586184 0,06786219 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,04586184 0,06782112 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,04586184 0,06778009 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04586184 0,06773911 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04586184 0,06769818 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,04586184 0,0676573 ! NAD metabolic process GO:0019674 33 17 0,000 0,04586184 0,06761647 ! membrane budding GO:0006900 42 17 0,000 0,04586184 0,06757568 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04586184 0,06753495 ! regulation of protein binding GO:0043393 33 17 0,000 0,04586184 0,06749427 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04586184 0,06745363 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04586184 0,06741305 ! genitalia development GO:0048806 32 17 0,000 0,04586184 0,06737251 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04586184 0,06733202 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,04586184 0,06729158 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04586184 0,06725119 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04586184 0,06721085 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,04586184 0,06717055 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04586184 0,06713031 ! steroid catabolic process GO:0006706 34 17 0,000 0,04586184 0,06709011 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04586184 0,06704996 ! gas transport GO:0015669 26 17 0,000 0,04586184 0,06700986 ! organic cation transport GO:0015695 32 17 0,000 0,04586184 0,06696981 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,04586184 0,0669298 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04586184 0,06688984 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04586184 0,06684993 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0484938 0,07064422 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0484938 0,07060212 ! limbic system development GO:0021761 40 18 0,000 0,0484938 0,07056007 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0484938 0,07051807 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0484938 0,07047612 ! adult walking behavior GO:0007628 36 18 0,000 0,0484938 0,07043422 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0484938 0,07039237 ! heart looping GO:0001947 34 18 0,000 0,0484938 0,07035057 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0484938 0,07030882 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0484938 0,07026711 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,0484938 0,07022546 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0484938 0,07018386 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,0484938 0,07014231 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0484938 0,0701008 ! response to retinoic acid GO:0032526 31 18 0,000 0,0484938 0,07005935 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,0484938 0,07001794 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0484938 0,06997658 ! DNA integration GO:0015074 32 18 0,000 0,0484938 0,06993527 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,0484938 0,06989401 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0484938 0,0698528 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0484938 0,06981164 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0484938 0,06977053 ! neural crest cell migration GO:0001755 41 18 0,000 0,0484938 0,06972946 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0484938 0,06968844 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0484938 0,06964748 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,0484938 0,06960655 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0484938 0,06956568 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0484938 0,06952486 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0484938 0,06948408 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,0484938 0,06944335 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0484938 0,06940267 ! nerve development GO:0021675 34 18 0,000 0,0484938 0,06936203 ! defense response to virus GO:0051607 43 18 0,000 0,0484938 0,06932145 ! microspike assembly GO:0030035 46 18 0,000 0,0484938 0,06928091 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0484938 0,06924042 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05111857 0,07294548 ! positive regulation of translation GO:0045727 31 19 0,000 0,05111857 0,0729029 ! negative regulation of defense response GO:0031348 27 19 0,000 0,05111857 0,07286037 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,05111857 0,07281788 ! neuron maturation GO:0042551 46 19 0,000 0,05111857 0,07277545 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05111857 0,07273306 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05111857 0,07269073 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05111857 0,07264844 ! inositol metabolic process GO:0006020 33 19 0,000 0,05111857 0,0726062 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05111857 0,07256402 ! memory GO:0007613 34 19 0,000 0,05111857 0,07252188 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05111857 0,07247979 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05111857 0,07243774 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,05111857 0,07239575 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05111857 0,07235381 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,05111857 0,07231191 ! cerebral cortex development GO:0021987 40 19 0,000 0,05111857 0,07227006 ! pigmentation during development GO:0048066 42 19 0,000 0,05111857 0,07222826 ! response to vitamin A GO:0033189 32 19 0,000 0,05111857 0,07218651 ! heme metabolic process GO:0042168 40 19 0,000 0,05111857 0,07214481 ! neuromuscular junction development GO:0007528 43 19 0,000 0,05111857 0,07210316 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05111857 0,07206155 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,05111857 0,07201999 ! response to fungus GO:0009620 26 19 0,000 0,05111857 0,07197848 ! peptide cross-linking GO:0018149 39 19 0,000 0,05111857 0,07193702 ! protein export from nucleus GO:0006611 40 19 0,000 0,05111857 0,07189561 ! heart process GO:0003015 32 19 0,000 0,05111857 0,07185424 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05111857 0,07181292 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05111857 0,07177165 ! visual learning GO:0008542 38 19 0,000 0,05111857 0,07173043 ! cellular pigmentation GO:0033059 37 19 0,000 0,05111857 0,07168925 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05111857 0,07164812 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05111857 0,07160704 ! vitamin transport GO:0051180 31 19 0,000 0,05111857 0,071566 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05111857 0,07152501 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05111857 0,07148407 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05111857 0,07144318 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05111857 0,07140233 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05111857 0,07136153 ! cilium assembly GO:0042384 38 19 0,000 0,05111857 0,07132077 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05111857 0,07128006 ! protein secretion GO:0009306 45 20 0,000 0,05373618 0,07488732 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,05373618 0,07484463 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,05373618 0,07480198 ! positive regulation of ossification GO:0045778 50 20 0,000 0,05373618 0,07475938 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,05373618 0,07471683 ! skin development GO:0043588 42 20 0,000 0,05373618 0,07467433 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,05373618 0,07463188 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,05373618 0,07458948 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,05373618 0,07454712 ! response to vitamin GO:0033273 36 20 0,000 0,05373618 0,07450481 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,05373618 0,07446255 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,05373618 0,07442034 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,05373618 0,07437817 ! bile acid metabolic process GO:0008206 34 20 0,000 0,05373618 0,07433606 ! response to alkaloid GO:0043279 38 20 0,000 0,05373618 0,07429399 ! retinoid metabolic process GO:0001523 34 20 0,000 0,05373618 0,07425197 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,05373618 0,07420999 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,05373618 0,07416807 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,05373618 0,07412619 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,05373618 0,07408435 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,05373618 0,07404257 ! body fluid secretion GO:0007589 33 20 0,000 0,05373618 0,07400083 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,05373618 0,07395914 ! peptide secretion GO:0002790 38 20 0,000 0,05373618 0,0739175 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,05373618 0,0738759 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,05373618 0,07383435 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,05373618 0,07379285 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,05373618 0,07375139 ! cell-cell junction organization GO:0045216 43 20 0,000 0,05373618 0,07370998 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,05373618 0,07366862 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,05373618 0,0736273 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,05373618 0,07358603 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,05373618 0,0735448 ! regulation of glucose import GO:0046324 30 20 0,000 0,05373618 0,07350363 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,05373618 0,07346249 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,05373618 0,07342141 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,05373618 0,07338037 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,05373618 0,07333937 ! regulation of cell killing GO:0031341 46 21 0,000 0,05634663 0,0768592 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05634663 0,07681631 ! hormone secretion GO:0046879 39 21 0,000 0,05634663 0,07677346 ! cAMP metabolic process GO:0046058 41 21 0,000 0,05634663 0,07673067 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05634663 0,07668792 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05634663 0,07664522 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,05634663 0,07660257 ! ovarian follicle development GO:0001541 39 21 0,000 0,05634663 0,07655997 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05634663 0,07651741 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05634663 0,0764749 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,05634663 0,07643244 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05634663 0,07639002 ! plasma membrane fusion GO:0045026 33 21 0,000 0,05634663 0,07634765 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,05634663 0,07630533 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05634663 0,07626306 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,05634663 0,07622083 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05634663 0,07617865 ! diencephalon development GO:0021536 36 21 0,000 0,05634663 0,07613652 ! collagen fibril organization GO:0030199 62 21 0,000 0,05634663 0,07609443 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,05634663 0,07605239 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,05634663 0,07601039 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,05634663 0,07596844 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05634663 0,07592654 ! collagen catabolic process GO:0030574 29 21 0,000 0,05634663 0,07588469 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05634663 0,07584288 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05634663 0,07580111 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05634663 0,0757594 ! actin filament-based movement GO:0030048 47 21 0,000 0,05634663 0,07571772 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,05634663 0,0756761 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,05894996 0,07912898 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,05894996 0,07908553 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,05894996 0,07904213 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,05894996 0,07899877 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,05894996 0,07895546 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,05894996 0,07891219 ! microtubule-based transport GO:0010970 59 22 0,000 0,05894996 0,07886898 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,05894996 0,07882581 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,05894996 0,07878269 ! cellular response to starvation GO:0009267 37 22 0,000 0,05894996 0,07873961 ! vacuolar transport GO:0007034 41 22 0,000 0,05894996 0,07869659 ! central nervous system neuron development GO:0021954 47 22 0,000 0,05894996 0,07865361 ! fucose metabolic process GO:0006004 44 22 0,000 0,05894996 0,07861067 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,05894996 0,07856779 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,05894996 0,07852495 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,05894996 0,07848215 ! stem cell differentiation GO:0048863 57 22 0,000 0,05894996 0,07843941 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,05894996 0,07839671 ! cytolysis GO:0019835 27 22 0,000 0,05894996 0,07835405 ! renal system process GO:0003014 42 22 0,000 0,05894996 0,07831145 ! vasodilation GO:0042311 40 22 0,000 0,05894996 0,07826889 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,05894996 0,07822637 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,05894996 0,0781839 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,05894996 0,07814148 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,05894996 0,07809911 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,05894996 0,07805678 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,05894996 0,07801449 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,05894996 0,07797225 ! sarcomere organization GO:0045214 32 22 0,000 0,05894996 0,07793006 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,05894996 0,07788791 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,05894996 0,07784581 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,05894996 0,07780376 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,05894996 0,07776175 ! gut development GO:0048565 44 22 0,000 0,05894996 0,07771978 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,05894996 0,07767786 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,05894996 0,07763599 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,05894996 0,07759416 ! protein stabilization GO:0050821 41 22 0,000 0,05894996 0,07755237 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,06154618 0,08092428 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06154618 0,08088075 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06154618 0,08083727 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06154618 0,08079383 ! gluconeogenesis GO:0006094 38 23 0,000 0,06154618 0,08075044 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06154618 0,08070709 ! viral genome replication GO:0019079 44 23 0,000 0,06154618 0,0806638 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06154618 0,08062055 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06154618 0,08057734 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,06154618 0,08053418 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06154618 0,08049107 ! regeneration GO:0031099 42 23 0,000 0,06154618 0,080448 ! axis specification GO:0009798 43 23 0,000 0,06154618 0,08040498 ! visual behavior GO:0007632 46 23 0,000 0,06154618 0,08036201 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,06154618 0,08031908 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06154618 0,0802762 ! response to ethanol GO:0045471 47 23 0,000 0,06154618 0,08023336 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06154618 0,08019057 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,06154618 0,08014782 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06154618 0,08010512 ! peroxisome organization GO:0007031 43 23 0,000 0,06154618 0,08006247 ! lysosome organization GO:0007040 47 23 0,000 0,06154618 0,08001986 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,06154618 0,0799773 ! vesicle targeting GO:0006903 49 23 0,000 0,06154618 0,07993478 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,06154618 0,0798923 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06154618 0,07984988 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06154618 0,07980749 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06154618 0,07976515 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06154618 0,07972286 ! DNA modification GO:0006304 36 23 0,000 0,06154618 0,07968061 ! fatty acid transport GO:0015908 47 23 0,000 0,06154618 0,07963841 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06154618 0,07959625 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06154618 0,07955414 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06154618 0,07951207 ! hormone transport GO:0009914 41 23 0,000 0,06154618 0,07947004 ! cell-cell recognition GO:0009988 28 23 0,000 0,06154618 0,07942806 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06154618 0,07938612 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06154618 0,07934423 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06154618 0,07930238 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,06413531 0,08259492 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06413531 0,0825514 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,06413531 0,08250793 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,06413531 0,08246451 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,06413531 0,08242113 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06413531 0,08237779 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,06413531 0,0823345 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06413531 0,08229126 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06413531 0,08224806 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,06413531 0,08220491 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06413531 0,0821618 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06413531 0,08211874 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06413531 0,08207573 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,06413531 0,08203275 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,06413531 0,08198983 ! sex determination GO:0007530 48 24 0,000 0,06413531 0,08194695 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06413531 0,08190411 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06413531 0,08186132 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06413531 0,08181857 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06413531 0,08177587 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06413531 0,08173321 ! pallium development GO:0021543 56 24 0,000 0,06413531 0,08169059 ! oogenesis GO:0048477 44 24 0,000 0,06413531 0,08164803 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06413531 0,0816055 ! platelet activation GO:0030168 41 24 0,000 0,06413531 0,08156302 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06413531 0,08152058 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06413531 0,08147819 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06413531 0,08143584 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06413531 0,08139354 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06413531 0,08135128 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,06413531 0,08130906 ! regulation of amine transport GO:0051952 41 24 0,000 0,06413531 0,08126689 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,06671737 0,08449483 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06671737 0,08445105 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06671737 0,08440732 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,06671737 0,08436363 ! phototransduction GO:0007602 37 25 0,000 0,06671737 0,08431998 ! keratinization GO:0031424 37 25 0,000 0,06671737 0,08427639 ! vacuole organization GO:0007033 49 25 0,000 0,06671737 0,08423283 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06671737 0,08418932 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,06671737 0,08414586 ! receptor metabolic process GO:0043112 53 25 0,000 0,06671737 0,08410244 ! chromosome condensation GO:0030261 48 25 0,000 0,06671737 0,08405907 ! regulation of behavior GO:0050795 48 25 0,000 0,06671737 0,08401574 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,06671737 0,08397245 ! interaction with host GO:0051701 66 25 0,000 0,06671737 0,08392921 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,06671737 0,08388602 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06671737 0,08384287 ! immunoglobulin production GO:0002377 62 25 0,000 0,06671737 0,08379976 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,06671737 0,0837567 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,06671737 0,08371368 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06671737 0,0836707 ! liver development GO:0001889 55 25 0,000 0,06671737 0,08362777 ! protein tetramerization GO:0051262 57 25 0,000 0,06671737 0,08358489 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,06929238 0,08676641 ! myelination GO:0042552 50 26 0,000 0,06929238 0,08672196 ! initiation of viral infection GO:0019059 60 26 0,000 0,06929238 0,08667756 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,06929238 0,0866332 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,06929238 0,08658889 ! molting cycle process GO:0022404 52 26 0,000 0,06929238 0,08654462 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,06929238 0,0865004 ! spinal cord development GO:0021510 54 26 0,000 0,06929238 0,08645622 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,06929238 0,08641208 ! digestive system process GO:0022600 49 26 0,000 0,06929238 0,086368 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,06929238 0,08632395 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,06929238 0,08627996 ! neural crest cell development GO:0014032 59 26 0,000 0,06929238 0,086236 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,06929238 0,08619209 ! negative regulation of cell development GO:0010721 83 26 0,000 0,06929238 0,08614823 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,06929238 0,08610441 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,06929238 0,08606064 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,06929238 0,08601691 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,06929238 0,08597322 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,06929238 0,08592958 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,06929238 0,08588598 ! blastocyst development GO:0001824 50 26 0,000 0,06929238 0,08584243 ! telomere organization GO:0032200 46 26 0,000 0,06929238 0,08579892 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,06929238 0,08575546 ! neural tube closure GO:0001843 58 26 0,000 0,06929238 0,08571204 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,06929238 0,08566866 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,06929238 0,08562533 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,06929238 0,08558204 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,07186035 0,08870886 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,07186035 0,08866406 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,07186035 0,0886193 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,07186035 0,08857459 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,07186035 0,08852992 ! superoxide metabolic process GO:0006801 41 27 0,000 0,07186035 0,0884853 ! tube lumen formation GO:0035148 59 27 0,000 0,07186035 0,08844072 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,07186035 0,08839619 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,07186035 0,08835171 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,07186035 0,08830726 ! response to starvation GO:0042594 47 27 0,000 0,07186035 0,08826286 ! response to toxin GO:0009636 49 27 0,000 0,07186035 0,08821851 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,07186035 0,0881742 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,07186035 0,08812994 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,07186035 0,08808572 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,07186035 0,08804154 ! leukocyte proliferation GO:0070661 59 27 0,000 0,07186035 0,08799741 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,07186035 0,08795333 ! neuron fate commitment GO:0048663 52 28 0,000 0,07442131 0,0910422 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07442131 0,09099663 ! circadian rhythm GO:0007623 56 28 0,000 0,07442131 0,09095111 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,07442131 0,09090563 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07442131 0,0908602 ! sperm motility GO:0030317 37 28 0,000 0,07442131 0,09081482 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07442131 0,09076948 ! base-excision repair GO:0006284 41 28 0,000 0,07442131 0,09072419 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,07442131 0,09067894 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07442131 0,09063373 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,07442131 0,09058857 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07442131 0,09054346 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07442131 0,09049839 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07442131 0,09045337 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,07442131 0,09040839 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07442131 0,09036345 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,07442131 0,09031856 ! lipid oxidation GO:0034440 48 28 0,000 0,07442131 0,09027372 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,07442131 0,09022892 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,07697528 0,09327907 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,07697528 0,09323283 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,07697528 0,09318663 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,07697528 0,09314047 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,07697528 0,09309436 ! primary neural tube formation GO:0014020 61 29 0,000 0,07697528 0,0930483 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,07697528 0,09300228 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,07697528 0,09295631 ! synaptogenesis GO:0007416 46 29 0,000 0,07697528 0,09291038 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,07697528 0,0928645 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,07697528 0,09281866 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,07697528 0,09277287 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,07697528 0,09272713 ! phenol metabolic process GO:0018958 56 30 0,000 0,07952227 0,09574811 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,07952227 0,09570094 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,07952227 0,09565382 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,07952227 0,09560675 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,07952227 0,09555972 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,07952227 0,09551274 ! acute-phase response GO:0006953 50 30 0,000 0,07952227 0,0954658 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,07952227 0,09541892 ! myofibril assembly GO:0030239 50 30 0,000 0,07952227 0,09537207 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,07952227 0,09532528 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,07952227 0,09527852 ! cell fate determination GO:0001709 64 30 0,000 0,07952227 0,09523182 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,07952227 0,09518516 ! phospholipid transport GO:0015914 65 30 0,000 0,07952227 0,09513855 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,07952227 0,09509198 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,07952227 0,09504546 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,07952227 0,09499898 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,07952227 0,09495255 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,07952227 0,09490616 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,08206231 0,09788976 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,08206231 0,09784198 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,08206231 0,09779425 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,08206231 0,09774657 ! cell junction assembly GO:0034329 85 31 0,000 0,08206231 0,09769894 ! regulation of innate immune response GO:0045088 57 31 0,000 0,08206231 0,09765135 ! ovulation cycle process GO:0022602 55 31 0,000 0,08206231 0,09760381 ! peptide transport GO:0015833 60 31 0,000 0,08206231 0,09755631 ! male gonad development GO:0008584 56 31 0,000 0,08206231 0,09750886 ! detection of light stimulus GO:0009583 44 31 0,000 0,08206231 0,09746146 ! natural killer cell activation GO:0030101 50 31 0,000 0,08206231 0,0974141 ! ensheathment of neurons GO:0007272 64 31 0,000 0,08206231 0,09736679 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,08206231 0,09731952 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,08206231 0,0972723 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,08206231 0,09722513 ! eye morphogenesis GO:0048592 65 31 0,000 0,08206231 0,097178 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,08206231 0,09713092 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,08459541 0,10008067 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,08459541 0,10003222 ! collagen metabolic process GO:0032963 49 32 0,000 0,08459541 0,09998383 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,08459541 0,09993548 ! spindle organization GO:0007051 50 32 0,000 0,08459541 0,09988718 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,08459541 0,09983893 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,08459541 0,09979072 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,08459541 0,09974256 ! muscle cell development GO:0055001 52 32 0,000 0,08459541 0,09969444 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,08459541 0,09964637 ! ovulation cycle GO:0042698 57 32 0,000 0,08459541 0,09959835 ! peripheral nervous system development GO:0007422 68 32 0,000 0,08459541 0,09955037 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,08459541 0,09950244 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,08459541 0,09945456 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,08459541 0,09940672 ! gene silencing GO:0016458 71 32 0,000 0,08459541 0,09935893 ! regulation of pH GO:0006885 56 33 0,000 0,08712158 0,1022768 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,08712158 0,10222768 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,08712158 0,1021786 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,08712158 0,10212957 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,08712158 0,10208059 ! response to ionizing radiation GO:0010212 74 33 0,000 0,08712158 0,10203165 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,08712158 0,10198276 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,08712158 0,10193392 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,08712158 0,10188513 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,08712158 0,10183638 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,08712158 0,10178768 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,08712158 0,10173902 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,08712158 0,10169041 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,08964086 0,10458101 ! glial cell differentiation GO:0010001 67 34 0,000 0,08964086 0,10453109 ! post-embryonic development GO:0009791 76 34 0,000 0,08964086 0,10448122 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,08964086 0,10443139 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,08964086 0,10438161 ! spliceosome assembly GO:0000245 75 34 0,000 0,08964086 0,10433189 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,08964086 0,1042822 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,08964086 0,10423257 ! adult locomotory behavior GO:0008344 62 34 0,000 0,08964086 0,10418298 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,08964086 0,10413344 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,09215326 0,10700115 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,09215326 0,10695031 ! negative regulation of secretion GO:0051048 68 35 0,000 0,09215326 0,10689953 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,09215326 0,10684879 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,09215326 0,10679811 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,09215326 0,10674747 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,09215326 0,10669688 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,09215326 0,10664633 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,09215326 0,10659584 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,09215326 0,10654539 ! ceramide metabolic process GO:0006672 72 35 0,000 0,09215326 0,10649499 ! telencephalon development GO:0021537 81 35 0,000 0,09215326 0,10644464 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,09215326 0,10639433 ! placenta development GO:0001890 53 35 0,000 0,09215326 0,10634408 ! vesicle localization GO:0051648 70 35 0,000 0,09215326 0,10629387 ! regulation of muscle development GO:0048634 82 36 0,000 0,09465879 0,10913234 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,09465879 0,10908086 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,09465879 0,10902943 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,09465879 0,10897805 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,09465879 0,10892672 ! positive regulation of cell development GO:0010720 85 36 0,000 0,09465879 0,10887544 ! protein targeting to membrane GO:0006612 75 36 0,000 0,09465879 0,1088242 ! regulation of proteolysis GO:0030162 77 36 0,000 0,09465879 0,10877301 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,09465879 0,10872188 ! aerobic respiration GO:0009060 56 36 0,000 0,09465879 0,10867078 ! cytokine production GO:0001816 68 36 0,000 0,09465879 0,10861974 ! embryonic organ development GO:0048568 67 36 0,000 0,09465879 0,10856875 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,09465879 0,1085178 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,09465879 0,1084669 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,09715748 0,11127788 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,09715748 0,11122574 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,09715748 0,11117364 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,09715748 0,11112159 ! sister chromatid segregation GO:0000819 65 37 0,000 0,09715748 0,1110696 ! odontogenesis GO:0042476 74 37 0,000 0,09715748 0,11101765 ! actomyosin structure organization GO:0031032 68 37 0,000 0,09715748 0,11096574 ! cell junction organization GO:0034330 96 37 0,000 0,09715748 0,11091389 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,09715748 0,11086209 ! female gonad development GO:0008585 71 37 0,000 0,09715748 0,11081033 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,09715748 0,11075862 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,09715748 0,11070696 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,09964934 0,1134934 ! meiosis I GO:0007127 74 38 0,000 0,09964934 0,11344052 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,09964934 0,11338768 ! organic anion transport GO:0015711 82 38 0,000 0,09964934 0,11333489 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,09964934 0,11328215 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,09964934 0,11322946 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,09964934 0,11317682 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,09964934 0,11312423 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,09964934 0,11307169 ! regulation of protein stability GO:0031647 77 38 0,000 0,09964934 0,11301919 ! spermatid development GO:0007286 69 38 0,000 0,09964934 0,11296675 ! pigment metabolic process GO:0042440 87 38 0,000 0,09964934 0,11291435 ! neural tube formation GO:0001841 79 38 0,000 0,09964934 0,11286201 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,1021344 0,11562295 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,1021344 0,1155694 ! negative regulation of binding GO:0051100 71 39 0,000 0,1021344 0,1155159 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,1021344 0,11546244 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,1021344 0,11540904 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,1021344 0,11535568 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,1021344 0,11530237 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,1021344 0,11524912 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,10461266 0,11799111 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,10461266 0,11793666 ! learning GO:0007612 82 40 0,000 0,10461266 0,11788226 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,10461266 0,11782791 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,10461266 0,11777361 ! mismatch repair GO:0006298 58 40 0,000 0,10461266 0,11771936 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,10461266 0,11766517 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,10461266 0,11761102 ! RNA export from nucleus GO:0006405 61 41 0,000 0,10708416 0,12033422 ! mRNA catabolic process GO:0006402 79 41 0,000 0,10708416 0,1202789 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,10708416 0,12022362 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,10708416 0,1201684 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,10708416 0,12011322 ! gliogenesis GO:0042063 91 41 0,000 0,10708416 0,1200581 ! feeding behavior GO:0007631 69 41 0,000 0,10708416 0,12000303 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,10708416 0,11994801 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,10708416 0,11989303 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,10708416 0,11983811 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,10708416 0,11978324 ! spermatid differentiation GO:0048515 73 41 0,000 0,10708416 0,11972842 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,10708416 0,11967365 ! RNA modification GO:0009451 64 41 0,000 0,10708416 0,11961893 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,1095489 0,12231626 ! ear morphogenesis GO:0042471 64 42 0,000 0,1095489 0,12226038 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,1095489 0,12220455 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,1095489 0,12214878 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,1095489 0,12209305 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,1095489 0,12203738 ! regulation of protein secretion GO:0050708 77 42 0,000 0,1095489 0,12198175 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,1095489 0,12192618 ! cytokinesis GO:0000910 84 42 0,000 0,1095489 0,12187066 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,1095489 0,12181519 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,11200691 0,12449176 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,11200691 0,12443514 ! regulation of tube size GO:0035150 76 43 0,000 0,11200691 0,12437858 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,11200691 0,12432207 ! glucose transport GO:0015758 66 43 0,000 0,11200691 0,12426561 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,11200691 0,12420921 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,11200691 0,12415285 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,11200691 0,12409654 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,11200691 0,12404029 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,11200691 0,12398409 ! ion transmembrane transport GO:0034220 79 43 0,000 0,11200691 0,12392794 ! neuron migration GO:0001764 85 43 0,000 0,11200691 0,12387183 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,1144582 0,12652551 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,1144582 0,12646829 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,1144582 0,12641112 ! hexose transport GO:0008645 68 44 0,000 0,1144582 0,12635399 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,1144582 0,12629692 ! striated muscle contraction GO:0006941 85 44 0,000 0,1144582 0,1262399 ! phagocytosis GO:0006909 105 44 0,000 0,1144582 0,12618294 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,1144582 0,12612602 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,1169028 0,12876174 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,1169028 0,12870371 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,1169028 0,12864573 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,1169028 0,12858781 ! female gamete generation GO:0007292 71 45 0,000 0,1169028 0,12852994 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,1169028 0,12847212 ! polyol metabolic process GO:0019751 77 45 0,000 0,1169028 0,12841436 ! developmental growth GO:0048589 88 45 0,000 0,1169028 0,12835664 ! maintenance of location in cell GO:0051651 101 45 0,000 0,1169028 0,12829898 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,11934071 0,13091574 ! glycolysis GO:0006096 71 46 0,000 0,11934071 0,13085698 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,11934071 0,13079828 ! leukocyte migration GO:0050900 75 46 0,000 0,11934071 0,13073962 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,11934071 0,13068102 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,11934071 0,13062247 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,11934071 0,13056398 ! pigmentation GO:0043473 103 46 0,000 0,11934071 0,13050553 ! cell growth GO:0016049 90 46 0,000 0,11934071 0,13044714 ! neural tube development GO:0021915 91 47 0,000 0,12177196 0,13304513 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,12177196 0,13298565 ! positive regulation of defense response GO:0031349 88 48 0,000 0,12419657 0,13557293 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,12419657 0,13551238 ! mitochondrial transport GO:0006839 94 48 0,000 0,12419657 0,13545189 ! cellular component disassembly GO:0022411 89 48 0,000 0,12419657 0,13539144 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,12419657 0,13533106 ! endosome transport GO:0016197 127 48 0,000 0,12419657 0,13527072 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,12419657 0,13521044 ! male sex differentiation GO:0046661 93 48 0,000 0,12419657 0,13515021 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,12419657 0,13509004 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,12419657 0,13502992 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,12419657 0,13496985 ! response to calcium ion GO:0051592 94 49 0,000 0,12661456 0,1375364 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,12661456 0,13747527 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,12661456 0,1374142 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,12661456 0,13735318 ! JNK cascade GO:0007254 106 49 0,000 0,12661456 0,13729221 ! regulation of action potential GO:0001508 102 50 0,000 0,12902593 0,13984488 ! regulation of ion transport GO:0043269 86 50 0,000 0,12902593 0,13978286 ! endocrine system development GO:0035270 109 50 0,000 0,12902593 0,1397209 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,12902593 0,13965899 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,12902593 0,13959714 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,12902593 0,13953535 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,12902593 0,13947361 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,13143072 0,14201028 ! viral infectious cycle GO:0019058 104 51 0,000 0,13143072 0,1419475 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,13143072 0,14188477 ! peptide metabolic process GO:0006518 80 51 0,000 0,13143072 0,1418221 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,13143072 0,14175949 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,13143072 0,14169693 ! Notch signaling pathway GO:0007219 111 52 0,000 0,13382893 0,14421883 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,13382893 0,14415524 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,13382893 0,1440917 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,13382893 0,14402823 ! excretion GO:0007588 87 52 0,000 0,13382893 0,14396481 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,13382893 0,14390144 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,13382893 0,14383813 ! amino acid activation GO:0043038 98 52 0,000 0,13382893 0,14377488 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,13622059 0,14627996 ! positive regulation of growth GO:0045927 96 53 0,000 0,13622059 0,14621569 ! inner ear development GO:0048839 89 53 0,000 0,13622059 0,14615147 ! chromatin remodeling GO:0006338 122 53 0,000 0,13622059 0,14608731 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,13622059 0,14602321 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,13622059 0,14595917 ! cartilage development GO:0051216 99 53 0,000 0,13622059 0,14589518 ! synapse organization GO:0050808 102 53 0,000 0,13622059 0,14583124 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,13860571 0,14831965 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,13860571 0,14825471 ! neuromuscular process GO:0050905 107 54 0,000 0,13860571 0,14818983 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,13860571 0,148125 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,13860571 0,14806023 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,13860571 0,14799552 ! regulation of cell shape GO:0008360 142 54 0,000 0,13860571 0,14793087 ! RNA catabolic process GO:0006401 103 55 0,000 0,14098432 0,15040379 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,14098432 0,15033814 ! cell recognition GO:0008037 98 55 0,000 0,14098432 0,15027255 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,14098432 0,15020701 ! cell maturation GO:0048469 107 55 0,000 0,14098432 0,15014154 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,14098432 0,15007611 ! glucose catabolic process GO:0006007 88 56 0,000 0,14335642 0,15253473 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,14335642 0,15246832 ! regulation of DNA replication GO:0006275 105 56 0,000 0,14335642 0,15240197 ! chloride transport GO:0006821 102 57 0,000 0,14572204 0,15484947 ! heart morphogenesis GO:0003007 105 57 0,000 0,14572204 0,15478215 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,14572204 0,15471488 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,14808119 0,15715132 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,14808119 0,15708308 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,14808119 0,15701491 ! maintenance of location GO:0051235 124 58 0,000 0,14808119 0,15694679 ! nuclear export GO:0051168 110 59 0,000 0,15043389 0,15937121 ! establishment of organelle localization GO:0051656 122 59 0,000 0,15043389 0,15930212 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,15278016 0,16171661 ! DNA catabolic process GO:0006308 94 60 0,000 0,15278016 0,16164658 ! regulation of endocytosis GO:0030100 104 60 0,000 0,15278016 0,1615766 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,15278016 0,16150668 ! adult behavior GO:0030534 104 60 0,000 0,15278016 0,16143683 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,15512002 0,1638384 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,15512002 0,1637676 ! regulation of heart contraction GO:0008016 123 61 0,000 0,15512002 0,16369685 ! camera-type eye development GO:0043010 126 61 0,000 0,15512002 0,16362617 ! proton transport GO:0015992 117 61 0,000 0,15512002 0,16355555 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,15512002 0,16348499 ! viral reproductive process GO:0022415 132 62 0,000 0,15745349 0,16587273 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,15745349 0,16580124 ! tRNA processing GO:0008033 102 62 0,000 0,15745349 0,1657298 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,15745349 0,16565843 ! regulation of mitosis GO:0007088 112 63 0,000 0,15978057 0,16803441 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,15978057 0,1679621 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,15978057 0,16788986 ! hydrogen transport GO:0006818 121 64 0,000 0,16210129 0,17025514 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,16210129 0,17018197 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,16441567 0,17253757 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,16441567 0,17246349 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,16441567 0,17238947 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,16441567 0,17231552 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,16441567 0,17224163 ! ear development GO:0043583 114 66 0,000 0,16672372 0,17458467 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,16672372 0,17450987 ! gonad development GO:0008406 115 66 0,000 0,16672372 0,17443513 ! activation of MAPK activity GO:0000187 124 67 0,000 0,16902545 0,17676763 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,16902545 0,17669199 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,16902545 0,17661642 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,16902545 0,17654091 ! secondary metabolic process GO:0019748 125 67 0,000 0,16902545 0,17646546 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,1713209 0,17878554 ! hexose catabolic process GO:0019320 113 68 0,000 0,1713209 0,1787092 ! extracellular matrix organization GO:0030198 146 68 0,000 0,1713209 0,17863293 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,1713209 0,17855672 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,1713209 0,17848058 ! viral reproduction GO:0016032 142 68 0,000 0,1713209 0,1784045 ! adaptive immune response GO:0002250 126 68 0,000 0,1713209 0,17832849 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,1713209 0,17825254 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,17361007 0,18055743 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,17361007 0,18048059 ! developmental maturation GO:0021700 128 69 0,000 0,17361007 0,18040383 ! single fertilization GO:0007338 83 69 0,000 0,17361007 0,18032712 ! cell redox homeostasis GO:0045454 114 70 0,000 0,17589298 0,18262071 ! germ cell development GO:0007281 133 70 0,000 0,17589298 0,18254314 ! activation of immune response GO:0002253 120 70 0,000 0,17589298 0,18246562 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,17589298 0,18238818 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,17816964 0,18467053 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,17816964 0,18459221 ! appendage morphogenesis GO:0035107 150 72 0,000 0,18044009 0,18686525 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,18044009 0,18678607 ! actin filament organization GO:0007015 167 72 0,000 0,18044009 0,18670696 ! B cell activation GO:0042113 179 72 0,000 0,18044009 0,18662791 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,18044009 0,18654893 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,18044009 0,18647002 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,18044009 0,18639117 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,18044009 0,1863124 ! appendage development GO:0048736 151 73 0,000 0,18270432 0,18857062 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,18270432 0,18849098 ! regulation of immune effector process GO:0002697 156 73 0,000 0,18270432 0,18841142 ! acute inflammatory response GO:0002526 118 74 0,000 0,18496236 0,19065951 ! amino acid transport GO:0006865 148 74 0,000 0,18496236 0,1905791 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,18496236 0,19049875 ! organelle localization GO:0051640 155 74 0,000 0,18496236 0,19041848 ! reproductive structure development GO:0048608 131 75 0,000 0,18721423 0,19265558 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,18721423 0,19257446 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,18721423 0,19249341 ! eye development GO:0001654 155 75 0,000 0,18721423 0,19241243 ! axon guidance GO:0007411 162 75 0,000 0,18721423 0,19233152 ! rhythmic process GO:0048511 142 75 0,000 0,18721423 0,19225067 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,18945993 0,19447505 ! regulation of blood pressure GO:0008217 134 76 0,000 0,18945993 0,19439337 ! neurotransmitter transport GO:0006836 142 77 0,000 0,1916995 0,19660868 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,1916995 0,19652618 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,1916995 0,19644374 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,1916995 0,19636137 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,1916995 0,19627908 ! regulation of catabolic process GO:0009894 173 77 0,000 0,1916995 0,19619685 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,19393294 0,19839957 ! fertilization GO:0009566 99 78 0,000 0,19393294 0,19831652 ! blood coagulation GO:0007596 151 79 0,000 0,19616027 0,20051027 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,19616027 0,20042641 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,19616027 0,20034262 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,19838151 0,20252655 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,20500885 0,20920493 ! exocytosis GO:0006887 153 83 0,000 0,20500885 0,20911758 ! response to drug GO:0042493 149 83 0,000 0,20500885 0,20903031 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,20500885 0,2089431 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,20500885 0,20885597 ! inorganic anion transport GO:0015698 156 83 0,000 0,20500885 0,20876891 ! response to metal ion GO:0010038 158 84 0,000 0,20720588 0,21091832 ! response to nutrient GO:0007584 135 84 0,000 0,20720588 0,21083048 ! digestion GO:0007586 130 84 0,000 0,20720588 0,2107427 ! regulation of ligase activity GO:0051340 147 84 0,000 0,20720588 0,210655 ! hemostasis GO:0007599 165 85 0,000 0,20939691 0,21279395 ! negative regulation of transport GO:0051051 164 85 0,000 0,20939691 0,21270547 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,20939691 0,21261706 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,20939691 0,21252873 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,20939691 0,21244047 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,20939691 0,21235229 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,21158195 0,21447913 ! regulation of lyase activity GO:0051339 169 86 0,000 0,21158195 0,21439017 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,213761 0,21650834 ! mitochondrion organization GO:0007005 159 87 0,000 0,213761 0,21641862 ! alcohol catabolic process GO:0046164 142 87 0,000 0,213761 0,21632897 ! cellular respiration GO:0045333 143 88 0,000 0,2159341 0,21843768 ! amine biosynthetic process GO:0009309 146 88 0,000 0,2159341 0,21834727 ! sensory perception of smell GO:0007608 117 88 0,000 0,2159341 0,21825693 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,21810125 0,22035622 ! cellular defense response GO:0006968 123 89 0,000 0,21810125 0,22026513 ! regulation of neurological system process GO:0031644 175 89 0,000 0,21810125 0,22017411 ! response to inorganic substance GO:0010035 173 90 0,000 0,22026247 0,22226403 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,22026247 0,22217226 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,22241777 0,22425366 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,22671071 0,22848774 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,22671071 0,22839352 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,22671071 0,22829937 ! vitamin metabolic process GO:0006766 153 93 0,000 0,22671071 0,22820531 ! female pregnancy GO:0007565 166 94 0,000 0,22884838 0,23026219 ! sterol metabolic process GO:0016125 166 94 0,000 0,22884838 0,23016739 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,22884838 0,23007267 ! regulation of defense response GO:0031347 171 95 0,000 0,23098019 0,23212037 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,23098019 0,23202492 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,23098019 0,23192956 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,23098019 0,23183427 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,23098019 0,23173906 ! sex differentiation GO:0007548 171 96 0,000 0,23310618 0,23377602 ! regulation of T cell activation GO:0050863 175 96 0,000 0,23310618 0,23368009 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,23522634 0,23570876 ! forebrain development GO:0030900 210 98 0,000 0,2373407 0,23772995 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,2373407 0,23763252 ! mRNA transport GO:0051028 185 100 0,000 0,24155209 0,24175 ! positive regulation of immune response GO:0050778 175 100 0,000 0,24155209 0,241651 ! hormone metabolic process GO:0042445 171 100 0,000 0,24155209 0,24155209