pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1221-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 3,000 2,974E-08 7,155E-05 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 4,941E-08 5,944E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 5,68E-08 4,556E-05 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 3,635E-07 2,186E-04 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 9,648E-07 4,643E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 1,111E-06 4,454E-04 ! ER overload response GO:0006983 12 8 2,000 3,405E-06 1,17E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 4,596E-06 1,382E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 2,000 7,253E-06 1,939E-03 ! protein sumoylation GO:0016925 15 10 2,000 7,253E-06 1,745E-03 ! regulation of embryonic development GO:0045995 27 11 2,000 9,944E-06 2,175E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 1,322E-05 2,651E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 1,322E-05 2,447E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 2,71E-05 4,658E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 3,437E-05 5,512E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 4,027E-05 6,056E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 4,819E-05 6,82E-03 ! positive regulation of growth GO:0045927 90 52 3,000 5,597E-05 7,482E-03 ! response to UV GO:0009411 104 53 3,000 6,036E-05 7,643E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 6,693E-05 8,051E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 6,693E-05 7,668E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 6,693E-05 7,319E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 8,042E-05 8,413E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 8,989E-05 9,011E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 9,837E-05 9,467E-03 ! sex determination GO:0007530 47 23 2,000 1,031E-04 9,538E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 1,175E-04 0,01046626 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 1,175E-04 0,01009246 ! protein tetramerization GO:0051262 52 24 2,000 1,175E-04 9,744E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,331E-04 0,01067305 ! interaction with host GO:0051701 62 25 2,000 1,331E-04 0,01032876 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 1,5E-04 0,01127827 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,562E-04 0,01138922 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,562E-04 0,01105425 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,562E-04 0,01073841 ! anagen GO:0042640 6 5 1,000 1,562E-04 0,01044012 ! skeletal myofibril assembly GO:0014866 10 5 1,000 1,562E-04 0,01015796 ! valine metabolic process GO:0006573 10 5 1,000 1,562E-04 9,891E-03 ! response to food GO:0032094 6 5 1,000 1,562E-04 9,637E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 1,562E-04 9,396E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 1,562E-04 9,167E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 1,562E-04 8,949E-03 GO:0051930|regulation of sensory perception of pain, ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,683E-04 9,415E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 1,697E-04 9,277E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,879E-04 0,01004676 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 1,879E-04 9,828E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 2,09E-04 0,01069802 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 2,315E-04 0,01160529 ! regulation of B cell activation GO:0050864 50 30 2,000 2,315E-04 0,01136844 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,337E-04 0,0112459 ! male sex determination GO:0030238 15 6 1,000 2,337E-04 0,0110254 ! establishment of spindle localization GO:0051293 12 6 1,000 2,337E-04 0,01081337 GO:0051653|spindle localization, ! hair follicle maturation GO:0048820 7 6 1,000 2,337E-04 0,01060934 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,337E-04 0,01041287 ! positive regulation of catabolic process GO:0009896 64 32 2,000 2,812E-04 0,01230176 ! regulation of helicase activity GO:0051095 15 7 1,000 3,263E-04 0,0140207 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,263E-04 0,01377473 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,263E-04 0,01353723 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 3,263E-04 0,01330779 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,263E-04 0,01308599 ! B cell lineage commitment GO:0002326 21 7 1,000 3,263E-04 0,01287146 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 3,263E-04 0,01266386 ! T cell lineage commitment GO:0002360 16 7 1,000 3,263E-04 0,01246285 ! response to tumor cell GO:0002347 13 7 1,000 3,263E-04 0,01226811 ! regulation of respiratory burst GO:0060263 11 7 1,000 3,263E-04 0,01207937 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 3,373E-04 0,01229629 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 4,001E-04 0,01436907 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,34E-04 0,01535513 ! succinate metabolic process GO:0006105 14 8 1,000 4,34E-04 0,01513259 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,34E-04 0,01491641 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 4,34E-04 0,01470632 ! glycogen metabolic process GO:0005977 61 37 2,000 4,342E-04 0,01450887 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 4,7E-04 0,01549169 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 2,000 4,7E-04 0,01528234 GO:0006073|cellular glucan metabolic process, ! mesenchymal cell development GO:0014031 87 40 2,000 5,473E-04 0,01755745 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of developmental growth GO:0048638 15 9 1,000 5,565E-04 0,01761811 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,565E-04 0,0173893 ! regulation of glycolysis GO:0006110 21 9 1,000 5,565E-04 0,01716636 ! phosphagen metabolic process GO:0006599 12 9 1,000 5,565E-04 0,01694907 GO:0006600|creatine metabolic process, ! protein heterooligomerization GO:0051291 16 9 1,000 5,565E-04 0,0167372 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 5,565E-04 0,01653057 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 5,77E-04 0,0169286 ! T cell differentiation GO:0030217 81 41 2,000 5,888E-04 0,01706812 ! interphase GO:0051325 213 98 3,000 6,487E-04 0,01857993 ! energy reserve metabolic process GO:0006112 74 43 2,000 6,777E-04 0,01918315 ! glucose transport GO:0015758 65 43 2,000 6,777E-04 0,01896009 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 6,938E-04 0,01918802 ! glucan biosynthetic process GO:0009250 14 10 1,000 6,938E-04 0,01896997 GO:0005978|glycogen biosynthetic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 6,938E-04 0,01875683 ! apical protein localization GO:0045176 15 10 1,000 6,938E-04 0,01854842 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 6,938E-04 0,01834459 GO:0043470|regulation of carbohydrate catabolic process, ! hexose transport GO:0008645 67 44 2,000 7,252E-04 0,01896536 GO:0015749|monosaccharide transport, ! regulation of actin filament polymerization GO:0030833 87 45 2,000 7,747E-04 0,02004337 ! glycolysis GO:0006096 65 45 2,000 7,747E-04 0,01983015 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 7,747E-04 0,01962141 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 8,264E-04 0,0207116 ! pigmentation GO:0043473 100 46 2,000 8,264E-04 0,02049808 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 8,458E-04 0,0207654 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 8,458E-04 0,02055565 ! regulation of intracellular pH GO:0051453 19 11 1,000 8,458E-04 0,02035009 ! DNA methylation GO:0006306 19 11 1,000 8,458E-04 0,02014861 GO:0006305|DNA alkylation, ! sequestering of metal ion GO:0051238 14 11 1,000 8,458E-04 0,01995107 ! positive regulation of cell cycle GO:0045787 89 48 2,000 9,362E-04 0,02186784 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 9,362E-04 0,02165757 ! virus-host interaction GO:0019048 29 12 1,000 1,012E-03 0,02319666 ! focal adhesion formation GO:0048041 35 12 1,000 1,012E-03 0,02297782 ! asymmetric protein localization GO:0008105 20 12 1,000 1,012E-03 0,02276308 ! entry into host cell GO:0030260 32 12 1,000 1,012E-03 0,02255231 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 1,012E-03 0,02234541 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,012E-03 0,02214227 ! T cell homeostasis GO:0043029 25 12 1,000 1,012E-03 0,02194279 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,117E-03 0,02400449 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to X-ray GO:0010165 25 13 1,000 1,193E-03 0,02540706 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,193E-03 0,0251842 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 1,193E-03 0,0249652 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,193E-03 0,02474998 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 2,000 1,25E-03 0,02569947 ! regulation of protein polymerization GO:0032271 103 53 2,000 1,25E-03 0,02548168 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,389E-03 0,02807376 ! response to gamma radiation GO:0010332 28 14 1,000 1,389E-03 0,02783981 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,389E-03 0,02760973 ! regulation of RNA stability GO:0043487 32 14 1,000 1,389E-03 0,02738342 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,389E-03 0,02716079 ! glucose catabolic process GO:0006007 82 55 2,000 1,392E-03 0,02699968 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 1,392E-03 0,02678368 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 1,392E-03 0,02657111 ! regulation of actin filament length GO:0030832 105 56 2,000 1,466E-03 0,02777364 ! regulation of DNA replication GO:0006275 101 56 2,000 1,466E-03 0,02755666 ! positive regulation of cell migration GO:0030335 126 57 2,000 1,543E-03 0,02877876 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,598E-03 0,0295747 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,598E-03 0,02934894 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,598E-03 0,0291266 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,598E-03 0,0289076 ! regulation of cellular component size GO:0032535 109 59 2,000 1,704E-03 0,03060381 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,821E-03 0,03246313 ! startle response GO:0001964 28 16 1,000 1,821E-03 0,03222443 ! DNA replication initiation GO:0006270 27 16 1,000 1,821E-03 0,03198921 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 1,821E-03 0,03175741 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,821E-03 0,03152894 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,876E-03 0,03224189 ! viral reproductive process GO:0022415 126 62 2,000 1,966E-03 0,03354397 ! regulation of mitosis GO:0007088 105 63 2,000 2,058E-03 0,03487226 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,058E-03 0,0346284 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,059E-03 0,03440236 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,059E-03 0,0341651 ! regulation of striated muscle contraction GO:0006942 21 17 1,000 2,059E-03 0,03393109 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 2,059E-03 0,03370027 ! positive regulation of cell motion GO:0051272 146 64 2,000 2,153E-03 0,03500279 ! germ cell development GO:0007281 118 65 2,000 2,251E-03 0,03634509 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,31E-03 0,03705793 ! positive regulation of proteolysis GO:0045862 31 18 1,000 2,31E-03 0,03681252 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,31E-03 0,03657033 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,31E-03 0,03633131 ! actin filament organization GO:0007015 148 66 2,000 2,351E-03 0,03673339 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 2,454E-03 0,03809705 ! negative regulation of cell growth GO:0030308 132 67 2,000 2,454E-03 0,03785284 ! activation of MAPK activity GO:0000187 115 67 2,000 2,454E-03 0,03761174 ! hexose catabolic process GO:0019320 104 67 2,000 2,454E-03 0,03737369 ! negative regulation of kinase activity GO:0033673 131 68 2,000 2,56E-03 0,03874076 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 2,56E-03 0,03849863 ! viral reproduction GO:0016032 134 68 2,000 2,56E-03 0,03825951 ! negative regulation of defense response GO:0031348 25 19 1,000 2,575E-03 0,03825002 ! lipid phosphorylation GO:0046834 35 19 1,000 2,575E-03 0,03801536 ! pigmentation during development GO:0048066 41 19 1,000 2,575E-03 0,03778356 ! actin filament bundle formation GO:0051017 42 19 1,000 2,575E-03 0,03755457 ! cellular pigmentation GO:0033059 36 19 1,000 2,575E-03 0,03732834 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 2,575E-03 0,03710481 ! cell cycle checkpoint GO:0000075 137 69 2,000 2,669E-03 0,03822153 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,854E-03 0,0406338 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 2,854E-03 0,04039478 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,854E-03 0,04015855 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 2,854E-03 0,03992507 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,854E-03 0,03969429 ! carbohydrate transport GO:0008643 110 72 2,000 3,012E-03 0,04164534 ! negative regulation of transferase activity GO:0051348 140 72 2,000 3,012E-03 0,04140736 ! cell aging GO:0007569 44 21 1,000 3,146E-03 0,04301277 ! DNA modification GO:0006304 34 21 1,000 3,146E-03 0,04276976 ! regulation of actin cytoskeleton organization GO:0032956 149 74 2,000 3,255E-03 0,04399362 ! eye development GO:0001654 143 74 2,000 3,255E-03 0,04374785 ! lymphocyte differentiation GO:0030098 167 75 2,000 3,381E-03 0,04518708 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 3,452E-03 0,04588755 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 3,452E-03 0,04563542 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 3,452E-03 0,04538604 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 3,452E-03 0,04513938 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,452E-03 0,04489538 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 3,452E-03 0,04465401 ! monosaccharide catabolic process GO:0046365 115 76 2,000 3,509E-03 0,04515277 ! regulation of catabolic process GO:0009894 161 76 2,000 3,509E-03 0,0449126 ! regulation of actin filament-based process GO:0032970 152 77 2,000 3,641E-03 0,04635237 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 3,641E-03 0,04610841 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,771E-03 0,04750284 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 3,771E-03 0,04725543 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 3,771E-03 0,04701058 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 3,771E-03 0,04676826 ! protein oligomerization GO:0051259 139 78 2,000 3,776E-03 0,0465888 ! protein import into nucleus GO:0006606 158 80 2,000 4,054E-03 0,04977043 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,103E-03 0,05011256 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,103E-03 0,04985947 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,103E-03 0,04960892 ! leukocyte homeostasis GO:0001776 44 24 1,000 4,103E-03 0,04936087 ! T cell activation GO:0042110 168 81 2,000 4,198E-03 0,0502541 ! nuclear import GO:0051170 161 81 2,000 4,198E-03 0,05000532 ! response to drug GO:0042493 143 82 2,000 4,345E-03 0,05150011 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 4,448E-03 0,05246462 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 4,448E-03 0,05220869 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 4,448E-03 0,05195525 ! vasculogenesis GO:0001570 46 25 1,000 4,448E-03 0,05170426 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,448E-03 0,05145568 ! negative regulation of DNA replication GO:0008156 42 25 1,000 4,448E-03 0,05120948 ! response to starvation GO:0042594 42 25 1,000 4,448E-03 0,05096563 ! negative regulation of cell development GO:0010721 73 25 1,000 4,448E-03 0,05072408 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 4,448E-03 0,05048482 ! cellular response to nutrient levels GO:0031669 41 25 1,000 4,448E-03 0,0502478 ! negative regulation of growth GO:0045926 155 84 2,000 4,648E-03 0,05226047 ! positive regulation of cell activation GO:0050867 145 85 2,000 4,804E-03 0,05376557 GO:0002696|positive regulation of leukocyte activation, ! initiation of viral infection GO:0019059 57 26 1,000 4,807E-03 0,05353984 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 4,807E-03 0,05329311 ! molting cycle process GO:0022404 50 26 1,000 4,807E-03 0,05304864 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,807E-03 0,05280641 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 4,807E-03 0,05256638 ! positive regulation of nuclear division GO:0051785 40 26 1,000 4,807E-03 0,05232853 GO:0045840|positive regulation of mitosis, ! mitochondrion organization GO:0007005 148 86 2,000 4,964E-03 0,05379735 ! alcohol catabolic process GO:0046164 130 86 2,000 4,964E-03 0,05355611 ! protein localization in nucleus GO:0034504 176 87 2,000 5,126E-03 0,05506262 ! protein amino acid acylation GO:0043543 55 27 1,000 5,178E-03 0,05536616 ! mitochondrial membrane organization GO:0007006 57 27 1,000 5,178E-03 0,05512118 ! male gonad development GO:0008584 44 27 1,000 5,178E-03 0,05487835 ! base-excision repair GO:0006284 41 27 1,000 5,178E-03 0,05463766 ! regulation of chromosome organization GO:0033044 42 27 1,000 5,178E-03 0,05439906 ! regulation of cell cycle process GO:0010564 149 90 2,000 5,633E-03 0,05892642 ! regulation of pH GO:0006885 43 29 1,000 5,958E-03 0,06205541 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 5,958E-03 0,06178793 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 6,169E-03 0,06369942 ! cell junction assembly GO:0034329 78 30 1,000 6,367E-03 0,06546549 ! myofibril assembly GO:0030239 47 30 1,000 6,367E-03 0,06518691 GO:0055002|striated muscle cell development, ! response to heat GO:0009408 50 30 1,000 6,367E-03 0,0649107 ! leukocyte differentiation GO:0002521 202 96 2,000 6,734E-03 0,0683616 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 6,788E-03 0,06862601 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 6,788E-03 0,06833888 ! iron ion homeostasis GO:0055072 54 31 1,000 6,788E-03 0,06805413 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 6,929E-03 0,06917366 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 7,222E-03 0,07180476 ! spindle organization GO:0007051 46 32 1,000 7,222E-03 0,07150926 ! pigment biosynthetic process GO:0046148 66 32 1,000 7,222E-03 0,07121619 ! metanephros development GO:0001656 74 32 1,000 7,222E-03 0,07092551 ! response to ionizing radiation GO:0010212 65 32 1,000 7,222E-03 0,0706372 ! muscle cell development GO:0055001 49 32 1,000 7,222E-03 0,07035122 ! skeletal muscle tissue development GO:0007519 186 99 2,000 7,329E-03 0,07110169 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 2,000 7,534E-03 0,07279718 ! DNA damage checkpoint GO:0000077 71 33 1,000 7,668E-03 0,07379982 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 7,668E-03 0,07350579 ! adult locomotory behavior GO:0008344 59 33 1,000 7,668E-03 0,07321411 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 8,126E-03 0,07728203 ! placenta development GO:0001890 53 34 1,000 8,126E-03 0,07697777 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 8,597E-03 0,08111257 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 8,597E-03 0,08079572 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 9,079E-03 0,08499519 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 9,079E-03 0,08466575 ! cell junction organization GO:0034330 86 36 1,000 9,079E-03 0,08433885 ! DNA integrity checkpoint GO:0031570 75 36 1,000 9,079E-03 0,08401447 ! regulation of proteolysis GO:0030162 72 36 1,000 9,079E-03 0,08369258 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 9,573E-03 0,08790948 ! meiosis I GO:0007127 65 37 1,000 9,573E-03 0,08757523 ! sister chromatid segregation GO:0000819 58 37 1,000 9,573E-03 0,0872435 ! actomyosin structure organization GO:0031032 62 37 1,000 9,573E-03 0,08691428 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 9,573E-03 0,08658753 ! pigment metabolic process GO:0042440 80 37 1,000 9,573E-03 0,08626324 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01007857 0,09048145 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01007857 0,09014509 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,01007857 0,08981122 GO:0042593|glucose homeostasis, ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01059591 0,0940729 ! segmentation GO:0035282 67 39 1,000 0,01059591 0,09372704 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01112478 0,09804478 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01112478 0,09768695 ! cytokinesis GO:0000910 72 40 1,000 0,01112478 0,09733173 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,01166509 0,10168914 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01221673 0,10611355 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01221673 0,10573185 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01221673 0,10535288 ! neuron migration GO:0001764 79 42 1,000 0,01221673 0,10497662 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01221673 0,10460304 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01277961 0,10903454 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01277961 0,10864926 ! male sex differentiation GO:0046661 76 44 1,000 0,01335363 0,11312969 ! double-strand break repair GO:0006302 81 44 1,000 0,01335363 0,11273274 ! biopolymer methylation GO:0043414 84 44 1,000 0,01335363 0,11233857 ! B cell differentiation GO:0030183 107 44 1,000 0,01335363 0,11194715 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01335363 0,11155845 ! developmental growth GO:0048589 82 44 1,000 0,01335363 0,11117243 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01335363 0,11078908 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01393869 0,11524569 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,01393869 0,11485102 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01453471 0,11935326 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01453471 0,1189473 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01514157 0,12349366 ! methylation GO:0032259 90 47 1,000 0,01514157 0,12307645 ! mitochondrial transport GO:0006839 82 48 1,000 0,0157592 0,12766545 ! activation of caspase activity GO:0006919 84 48 1,000 0,0157592 0,12723704 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,0157592 0,1268115 ! regulation of action potential GO:0001508 95 49 1,000 0,01638749 0,1314277 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,01638749 0,13099107 ! response to temperature stimulus GO:0009266 76 49 1,000 0,01638749 0,13055732 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01638749 0,13012644 ! neuromuscular process GO:0050905 99 50 1,000 0,01702636 0,13475467 ! histone modification GO:0016570 91 50 1,000 0,01702636 0,13431285 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01702636 0,13387392 ! viral infectious cycle GO:0019058 99 51 1,000 0,0176757 0,13852685 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,0176757 0,13807709 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,0176757 0,13763024 ! regulation of cell shape GO:0008360 125 51 1,000 0,0176757 0,13718627 ! positive regulation of binding GO:0051099 78 51 1,000 0,0176757 0,13674516 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,01833544 0,14139442 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01833544 0,14094268 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01900546 0,14562785 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01976548 0,1509706 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01976548 0,15049284 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01976548 0,1500181 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01976548 0,14954635 ! neuron fate determination GO:0048664 7 5 0,000 0,01976548 0,14907755 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01976548 0,14861168 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01976548 0,14814872 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01976548 0,14768863 ! polyol transport GO:0015791 12 5 0,000 0,01976548 0,14723139 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01976548 0,14677697 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01976548 0,14632535 ! response to superoxide GO:0000303 10 5 0,000 0,01976548 0,1458765 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01976548 0,14543039 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01976548 0,14498701 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01976548 0,14454632 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01976548 0,1441083 ! female meiosis GO:0007143 7 5 0,000 0,01976548 0,14367293 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01976548 0,14324018 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01976548 0,14281002 ! cobalt ion transport GO:0006824 11 5 0,000 0,01976548 0,14238245 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01976548 0,14195743 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01976548 0,14153494 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01976548 0,14111495 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01976548 0,14069745 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01976548 0,14028241 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01976548 0,13986982 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01976548 0,13945964 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01976548 0,13905187 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01976548 0,13864647 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01976548 0,13824343 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01976548 0,13784272 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01976548 0,13744433 ! negative chemotaxis GO:0050919 14 5 0,000 0,01976548 0,13704824 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01976548 0,13665442 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01976548 0,13626286 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01976548 0,13587354 ! behavioral response to pain GO:0048266 9 5 0,000 0,01976548 0,13548643 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01976548 0,13510153 ! Notch receptor processing GO:0007220 8 5 0,000 0,01976548 0,13471881 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01976548 0,13433824 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01976548 0,13395983 ! micturition GO:0060073 9 5 0,000 0,01976548 0,13358353 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01976548 0,13320935 ! copulation GO:0007620 9 5 0,000 0,01976548 0,13283726 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01976548 0,13246724 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01976548 0,13209927 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01976548 0,13173335 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01976548 0,13136944 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01976548 0,13100754 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01976548 0,13064763 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01976548 0,13028969 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01976548 0,12993371 ! grooming behavior GO:0007625 6 5 0,000 0,01976548 0,12957967 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01976548 0,12922755 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01976548 0,12887734 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01976548 0,12852902 ! response to protozoan GO:0001562 10 5 0,000 0,01976548 0,12818258 ! lymph vessel development GO:0001945 10 5 0,000 0,01976548 0,12783801 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01976548 0,12749528 ! endochondral ossification GO:0001958 16 5 0,000 0,01976548 0,12715438 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01976548 0,1268153 ! parathyroid gland development GO:0060017 13 5 0,000 0,01976548 0,12647803 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01976548 0,12614254 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01976548 0,12580883 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01976548 0,12547688 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01976548 0,12514668 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01976548 0,12481821 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01976548 0,12449146 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01976548 0,12416642 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01976548 0,12384307 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01976548 0,1235214 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01976548 0,12320139 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01976548 0,12288304 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01976548 0,12256634 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01976548 0,12225126 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01976548 0,12193779 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01976548 0,12162593 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01976548 0,12131566 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01976548 0,12100697 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01976548 0,12069984 ! histidine catabolic process GO:0006548 6 5 0,000 0,01976548 0,12039427 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01976548 0,12009025 ! microvillus organization GO:0032528 7 5 0,000 0,01976548 0,11978775 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01976548 0,11948678 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01976548 0,11918731 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01976548 0,11888935 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01976548 0,11859286 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01976548 0,11829786 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01976548 0,11800431 ! polyol catabolic process GO:0046174 7 5 0,000 0,01976548 0,11771222 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01976548 0,11742158 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01976548 0,11713236 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01976548 0,11684457 ! muscle cell migration GO:0014812 8 5 0,000 0,01976548 0,11655818 ! mitochondrial fission GO:0000266 8 5 0,000 0,01976548 0,1162732 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01976548 0,11598961 ! mRNA transcription GO:0009299 9 5 0,000 0,01976548 0,11570739 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01976548 0,11542655 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01976548 0,11514707 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01976548 0,11486893 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01976548 0,11459214 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01976548 0,11431668 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01976548 0,11404254 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01976548 0,11376971 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01976548 0,11349818 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01976548 0,11322795 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01976548 0,112959 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01976548 0,11269132 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01976548 0,11242491 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01976548 0,11215976 ! forebrain neuron development GO:0021884 13 5 0,000 0,01976548 0,11189585 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01976548 0,11163319 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01976548 0,11137175 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01976548 0,11111154 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01976548 0,11085254 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01976548 0,11059474 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01976548 0,11033814 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01976548 0,11008273 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01976548 0,10982849 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01976548 0,10957543 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01976548 0,10932354 ! basic amino acid transport GO:0015802 11 5 0,000 0,01976548 0,10907279 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01976548 0,1088232 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01976548 0,10857474 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01976548 0,10832742 ! depyrimidination GO:0045008 10 5 0,000 0,01976548 0,10808122 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01976548 0,10783614 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01976548 0,10759217 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01976548 0,1073493 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01976548 0,10710752 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01976548 0,10686683 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01976548 0,10662722 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01976548 0,10638868 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01976548 0,1061512 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01976548 0,10591478 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01976548 0,10567942 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01976548 0,1054451 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01976548 0,10521181 ! response to arsenic GO:0046685 10 5 0,000 0,01976548 0,10497955 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01976548 0,10474832 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01976548 0,10451811 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01976548 0,1042889 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01976548 0,1040607 ! response to cadmium ion GO:0046686 7 5 0,000 0,01976548 0,10383349 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01976548 0,10360727 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01976548 0,10338204 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01976548 0,10315778 ! decidualization GO:0046697 11 5 0,000 0,01976548 0,1029345 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01976548 0,10271218 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01976548 0,10249082 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01976548 0,1022704 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01976548 0,10205094 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01976548 0,10183242 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01976548 0,10161483 ! neural tube patterning GO:0021532 7 5 0,000 0,01976548 0,10139816 ! embryonic cleavage GO:0040016 6 5 0,000 0,01976548 0,10118242 ! peroxisome fission GO:0016559 5 5 0,000 0,01976548 0,1009676 ! histone demethylation GO:0016577 10 5 0,000 0,01976548 0,10075368 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01976548 0,10054067 ! mitotic recombination GO:0006312 9 5 0,000 0,01976548 0,10032856 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01976548 0,10011734 ! metaphase plate congression GO:0051310 7 5 0,000 0,01976548 0,09990701 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01976548 0,09969756 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01976548 0,09948899 ! enteric nervous system development GO:0048484 8 5 0,000 0,01976548 0,09928129 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01976548 0,09907445 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01976548 0,09886848 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01976548 0,09866336 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01976548 0,09845909 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01976548 0,09825566 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01976548 0,09805307 ! plasminogen activation GO:0031639 5 5 0,000 0,01976548 0,09785131 ! B cell homeostasis GO:0001782 13 5 0,000 0,01976548 0,09765039 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01976548 0,09745028 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01976548 0,097251 ! metaphase GO:0051323 8 5 0,000 0,01976548 0,09705253 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01976548 0,09685486 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01976548 0,096658 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01976548 0,09646194 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01976548 0,09626668 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01976548 0,0960722 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01976548 0,0958785 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01976548 0,09568559 ! response to redox state GO:0051775 5 5 0,000 0,01976548 0,09549345 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01976548 0,09530208 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01976548 0,09511148 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01976548 0,09492163 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01976548 0,09473255 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01976548 0,09454421 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01976548 0,09435662 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01976548 0,09416978 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01976548 0,09398367 ! striatum development GO:0021756 9 5 0,000 0,01976548 0,0937983 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01976548 0,09361366 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01976548 0,09342974 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01976548 0,09324655 ! glial cell migration GO:0008347 11 5 0,000 0,01976548 0,09306407 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01976548 0,0928823 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01976548 0,09270124 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01976548 0,09252089 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01976548 0,09234124 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01976548 0,09216228 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01976548 0,09198402 ! neuroprotection GO:0043526 6 5 0,000 0,01976548 0,09180644 ! neural plate development GO:0001840 8 5 0,000 0,01976548 0,09162955 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01976548 0,09145334 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01976548 0,09127781 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01976548 0,09110295 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01976548 0,09092875 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01976548 0,09075523 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01976548 0,09058236 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01976548 0,09041015 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01976548 0,09023859 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01976548 0,09006769 ! spindle assembly GO:0051225 6 5 0,000 0,01976548 0,08989743 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01976548 0,08972781 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01976548 0,08955883 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01976548 0,08939049 ! drug metabolic process GO:0017144 6 5 0,000 0,01976548 0,08922277 ! stem cell division GO:0017145 11 5 0,000 0,01976548 0,08905569 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01976548 0,08888923 ! organ regeneration GO:0031100 7 5 0,000 0,01976548 0,08872339 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01976548 0,08855817 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01976548 0,08839357 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01976548 0,08822957 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,02037604 0,09078659 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,02037604 0,09061878 ! aging GO:0007568 103 55 1,000 0,02037604 0,09045159 ! heart morphogenesis GO:0003007 97 55 1,000 0,02037604 0,09028501 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02107641 0,09321664 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02107641 0,0930456 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02107641 0,09287519 ! muscle fiber development GO:0048747 112 57 1,000 0,02178672 0,09582971 ! lipid modification GO:0030258 97 57 1,000 0,02178672 0,09565483 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02178672 0,0954806 ! maintenance of location GO:0051235 118 57 1,000 0,02178672 0,095307 ! adult behavior GO:0030534 99 58 1,000 0,02250687 0,09827865 ! establishment of organelle localization GO:0051656 109 59 1,000 0,02323678 0,10128206 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02367183 0,10299173 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02367183 0,10280582 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02367183 0,10262059 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02367183 0,10243602 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02367183 0,10225211 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02367183 0,10206887 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02367183 0,10188627 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02367183 0,10170433 ! sleep GO:0030431 13 6 0,000 0,02367183 0,10152304 ! response to oxygen radical GO:0000305 11 6 0,000 0,02367183 0,1013424 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02367183 0,10116239 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02367183 0,10098303 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02367183 0,1008043 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02367183 0,1006262 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02367183 0,10044872 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02367183 0,10027188 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02367183 0,10009565 ! forebrain regionalization GO:0021871 8 6 0,000 0,02367183 0,09992005 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02367183 0,09974506 ! male meiosis GO:0007140 7 6 0,000 0,02367183 0,09957068 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02367183 0,09939691 ! response to zinc ion GO:0010043 9 6 0,000 0,02367183 0,09922374 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02367183 0,09905118 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02367183 0,09887921 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02367183 0,09870785 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02367183 0,09853707 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02367183 0,09836689 ! malate metabolic process GO:0006108 11 6 0,000 0,02367183 0,09819729 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02367183 0,09802827 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02367183 0,09785984 ! protein refolding GO:0042026 15 6 0,000 0,02367183 0,09769198 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02367183 0,0975247 ! opsonization GO:0008228 8 6 0,000 0,02367183 0,09735799 ! mating behavior GO:0007617 7 6 0,000 0,02367183 0,09719185 ! neuron remodeling GO:0016322 15 6 0,000 0,02367183 0,09702628 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02367183 0,09686127 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02367183 0,09669682 ! equilibrioception GO:0050957 14 6 0,000 0,02367183 0,09653293 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02367183 0,09636959 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02367183 0,0962068 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02367183 0,09604456 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02367183 0,09588287 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02367183 0,09572173 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02367183 0,09556112 ! toxin metabolic process GO:0009404 11 6 0,000 0,02367183 0,09540105 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02367183 0,09524152 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02367183 0,09508252 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02367183 0,09492404 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02367183 0,0947661 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02367183 0,09460868 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02367183 0,09445179 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02367183 0,09429541 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02367183 0,09413955 ! thymic T cell selection GO:0045061 12 6 0,000 0,02367183 0,0939842 ! protein lipoylation GO:0009249 10 6 0,000 0,02367183 0,09382937 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02367183 0,09367504 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02367183 0,09352123 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02367183 0,09336791 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02367183 0,0932151 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02367183 0,09306279 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02367183 0,09291097 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02367183 0,09275965 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02367183 0,09260882 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02367183 0,09245849 ! hyperosmotic response GO:0006972 9 6 0,000 0,02367183 0,09230863 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02367183 0,09215927 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02367183 0,09201038 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02367183 0,09186198 ! urea metabolic process GO:0019627 7 6 0,000 0,02367183 0,09171405 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02367183 0,0915666 ! neutrophil activation GO:0042119 8 6 0,000 0,02367183 0,09141963 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02367183 0,09127312 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02367183 0,09112708 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02367183 0,09098151 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02367183 0,09083641 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02367183 0,09069176 ! neuron apoptosis GO:0051402 9 6 0,000 0,02367183 0,09054758 ! nucleoside salvage GO:0043174 9 6 0,000 0,02367183 0,09040385 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02367183 0,09026058 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02367183 0,09011776 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02367183 0,0899754 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02367183 0,08983348 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02367183 0,08969201 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02367183 0,08955099 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02367183 0,0894104 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02367183 0,08927026 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02367183 0,08913056 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02367183 0,08899129 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02367183 0,08885246 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02367183 0,08871406 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02367183 0,08857609 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02367183 0,08843855 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02367183 0,08830144 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02367183 0,08816475 ! neural nucleus development GO:0048857 14 6 0,000 0,02367183 0,08802848 ! response to UV-C GO:0010225 11 6 0,000 0,02367183 0,08789263 ! astrocyte development GO:0014002 15 6 0,000 0,02367183 0,08775721 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02367183 0,0876222 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02367183 0,0874876 ! interaction with symbiont GO:0051702 13 6 0,000 0,02367183 0,08735342 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02367183 0,08721964 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02367183 0,08708628 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02367183 0,08695332 ! response to copper ion GO:0046688 10 6 0,000 0,02367183 0,08682077 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02367183 0,08668863 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02367183 0,08655688 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02367183 0,08642553 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02367183 0,08629459 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02367183 0,08616403 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02367183 0,08603388 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02367183 0,08590411 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02367183 0,08577474 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02367183 0,08564575 ! Schwann cell development GO:0014044 15 6 0,000 0,02367183 0,08551716 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02367183 0,08538895 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02367183 0,08526112 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02367183 0,08513367 ! subpallium development GO:0021544 10 6 0,000 0,02367183 0,08500661 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02367183 0,08487992 ! histone ubiquitination GO:0016574 8 6 0,000 0,02367183 0,08475361 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02367183 0,08462768 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02367183 0,08450212 ! G2 phase GO:0051319 16 6 0,000 0,02367183 0,08437693 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02367183 0,08425211 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02367183 0,08412766 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02367183 0,08400358 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02367183 0,08387986 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02367183 0,08375651 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02367183 0,08363352 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02367183 0,08351089 ! receptor internalization GO:0031623 10 6 0,000 0,02367183 0,08338862 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02367183 0,08326671 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02367183 0,08314515 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02367183 0,08302395 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02367183 0,0829031 ! protein deubiquitination GO:0016579 14 6 0,000 0,02367183 0,0827826 ! protein destabilization GO:0031648 9 6 0,000 0,02367183 0,08266245 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02367183 0,08254265 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02367183 0,08242319 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02367183 0,08230409 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02367183 0,08218532 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02367183 0,0820669 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02367183 0,08194882 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02367183 0,08183107 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02367183 0,08171367 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02367183 0,0815966 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02367183 0,08147987 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02367183 0,08136347 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02367183 0,0812474 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02367183 0,08113166 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02367183 0,08101625 ! catecholamine transport GO:0051937 9 6 0,000 0,02367183 0,08090117 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02367183 0,08078642 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02367183 0,08067199 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02367183 0,08055789 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02367183 0,08044411 ! maternal placenta development GO:0001893 12 6 0,000 0,02367183 0,08033064 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02367183 0,0802175 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02367183 0,08010468 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02367183 0,07999217 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02367183 0,07987998 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02367183 0,0797681 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02367183 0,07965654 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02367183 0,07954529 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,02397636 0,08045624 ! regulation of heart contraction GO:0008016 110 60 1,000 0,02397636 0,08034418 ! camera-type eye development GO:0043010 116 60 1,000 0,02397636 0,08023244 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,02397636 0,08012101 ! kidney development GO:0001822 122 60 1,000 0,02397636 0,08000988 ! gonad development GO:0008406 98 62 1,000 0,02548418 0,08492374 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,02548418 0,08480628 ! tRNA transcription GO:0009304 14 7 0,000 0,02756275 0,09159665 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02756275 0,09147031 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02756275 0,09134431 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02756275 0,09121867 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02756275 0,09109337 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02756275 0,09096841 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02756275 0,0908438 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02756275 0,09071952 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02756275 0,09059559 ! prostate gland development GO:0030850 13 7 0,000 0,02756275 0,09047199 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02756275 0,09034873 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02756275 0,09022581 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02756275 0,09010322 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02756275 0,08998097 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02756275 0,08985904 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02756275 0,08973744 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02756275 0,08961618 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02756275 0,08949524 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02756275 0,08937462 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02756275 0,08925434 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02756275 0,08913437 ! glycolipid transport GO:0046836 10 7 0,000 0,02756275 0,08901473 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02756275 0,0888954 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02756275 0,0887764 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02756275 0,08865772 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02756275 0,08853935 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02756275 0,0884213 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02756275 0,08830356 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02756275 0,08818613 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02756275 0,08806902 ! mRNA stabilization GO:0048255 18 7 0,000 0,02756275 0,08795222 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02756275 0,08783572 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02756275 0,08771954 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02756275 0,08760366 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02756275 0,08748809 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02756275 0,08737282 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02756275 0,08725786 ! lipoprotein transport GO:0042953 14 7 0,000 0,02756275 0,0871432 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02756275 0,08702883 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02756275 0,08691477 ! rhythmic behavior GO:0007622 15 7 0,000 0,02756275 0,08680101 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02756275 0,08668754 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02756275 0,08657438 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02756275 0,0864615 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02756275 0,08634892 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02756275 0,08623663 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02756275 0,08612464 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02756275 0,08601293 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02756275 0,08590152 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02756275 0,08579039 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02756275 0,08567955 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02756275 0,085569 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02756275 0,08545873 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02756275 0,08534874 ! spinal cord patterning GO:0021511 13 7 0,000 0,02756275 0,08523904 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02756275 0,08512962 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02756275 0,08502048 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02756275 0,08491162 ! adrenal gland development GO:0030325 17 7 0,000 0,02756275 0,08480303 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02756275 0,08469473 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02756275 0,0845867 ! ovulation GO:0030728 9 7 0,000 0,02756275 0,08447894 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02756275 0,08437146 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02756275 0,08426426 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02756275 0,08415732 ! microtubule nucleation GO:0007020 20 7 0,000 0,02756275 0,08405066 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02756275 0,08394427 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02756275 0,08383814 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02756275 0,08373229 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02756275 0,0836267 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02756275 0,08352137 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02756275 0,08341632 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02756275 0,08331152 ! galactose metabolic process GO:0006012 13 7 0,000 0,02756275 0,08320699 ! vesicle fusion GO:0006906 17 7 0,000 0,02756275 0,08310272 ! response to dietary excess GO:0002021 8 7 0,000 0,02756275 0,08299871 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02756275 0,08289496 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02756275 0,08279147 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02756275 0,08268824 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02756275 0,08258527 ! organ growth GO:0035265 15 7 0,000 0,02756275 0,08248255 ! purine salvage GO:0043101 10 7 0,000 0,02756275 0,08238009 ! nucleoside transport GO:0015858 8 7 0,000 0,02756275 0,08227788 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02756275 0,08217592 ! parturition GO:0007567 14 7 0,000 0,02756275 0,08207422 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02756275 0,08197277 ! rRNA modification GO:0000154 14 7 0,000 0,02756275 0,08187157 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02756275 0,08177062 ! spindle checkpoint GO:0031577 15 7 0,000 0,02756275 0,08166992 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02756275 0,08156946 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02756275 0,08146925 ! macrophage differentiation GO:0030225 11 7 0,000 0,02756275 0,08136929 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02756275 0,08126957 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02756275 0,0811701 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02756275 0,08107087 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02756275 0,08097188 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02756275 0,08087314 ! fibrinolysis GO:0042730 10 7 0,000 0,02756275 0,08077463 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02756275 0,08067636 ! eating behavior GO:0042755 7 7 0,000 0,02756275 0,08057834 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02756275 0,08048055 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02756275 0,080383 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02756275 0,08028568 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02756275 0,0801886 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02756275 0,08009175 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02756275 0,07999514 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02756275 0,07989876 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02756275 0,07980261 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02756275 0,0797067 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02756275 0,07961101 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02756275 0,07951555 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02756275 0,07942033 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02756275 0,07932532 ! regulation of meiosis GO:0040020 12 7 0,000 0,02756275 0,07923055 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02756275 0,079136 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02756275 0,07904168 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02756275 0,07894759 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02756275 0,07885371 ! transcription termination GO:0006353 13 7 0,000 0,02756275 0,07876006 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02756275 0,07866663 ! anaphase GO:0051322 17 7 0,000 0,02756275 0,07857343 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02756275 0,07848044 ! axonal fasciculation GO:0007413 18 7 0,000 0,02756275 0,07838767 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02756275 0,07829513 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02756275 0,0782028 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02756275 0,07811068 ! diuresis GO:0030146 12 7 0,000 0,02756275 0,07801879 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02756275 0,07792711 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02756275 0,07783565 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02756275 0,0777444 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02756275 0,07765336 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02756275 0,07756254 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02756275 0,07747193 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02756275 0,07738153 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02756275 0,07729134 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02756275 0,07720136 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02756275 0,07711159 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02756275 0,07702203 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02756275 0,07693268 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02756275 0,07684354 ! lymph node development GO:0048535 10 7 0,000 0,02756275 0,0767546 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02756275 0,07666586 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02756275 0,07657733 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02756275 0,07648901 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02756275 0,07640089 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02756275 0,07631297 ! adult feeding behavior GO:0008343 9 7 0,000 0,02756275 0,07622525 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02756275 0,07613774 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02756275 0,07605043 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02756275 0,07596331 ! muscle adaptation GO:0043500 14 7 0,000 0,02756275 0,0758764 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02756275 0,07578968 ! retina homeostasis GO:0001895 12 7 0,000 0,02756275 0,07570316 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02756275 0,07561684 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02756275 0,07553072 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02756275 0,07544479 ! protein prenylation GO:0018342 18 7 0,000 0,02756275 0,07535906 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02756275 0,07527352 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02756275 0,07518818 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02756275 0,07510303 ! developmental maturation GO:0021700 116 66 1,000 0,02861205 0,07787398 ! lung development GO:0030324 144 67 1,000 0,02941691 0,0799741 ! chromosome segregation GO:0007059 113 67 1,000 0,02941691 0,07988383 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,02941691 0,07979377 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02941691 0,07970392 ! urogenital system development GO:0001655 137 69 1,000 0,03105349 0,08404353 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03143829 0,08498935 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03143829 0,08489396 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03143829 0,08479879 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03143829 0,08470383 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03143829 0,08460908 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03143829 0,08451454 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03143829 0,08442022 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03143829 0,08432611 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03143829 0,0842322 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03143829 0,08413851 ! meiotic prophase I GO:0007128 13 8 0,000 0,03143829 0,08404502 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03143829 0,08395174 ! oligopeptide transport GO:0006857 15 8 0,000 0,03143829 0,08385867 ! UTP metabolic process GO:0046051 8 8 0,000 0,03143829 0,0837658 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03143829 0,08367314 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03143829 0,08358068 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03143829 0,08348843 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03143829 0,08339638 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03143829 0,08330453 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03143829 0,08321289 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03143829 0,08312145 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03143829 0,08303021 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03143829 0,08293916 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03143829 0,08284832 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03143829 0,08275768 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03143829 0,08266723 ! reflex GO:0060004 16 8 0,000 0,03143829 0,08257698 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03143829 0,08248693 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03143829 0,08239708 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03143829 0,08230742 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03143829 0,08221795 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03143829 0,08212868 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03143829 0,08203961 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03143829 0,08195072 ! pigment granule organization GO:0048753 16 8 0,000 0,03143829 0,08186203 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03143829 0,08177353 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03143829 0,08168522 ! histidine metabolic process GO:0006547 16 8 0,000 0,03143829 0,08159711 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03143829 0,08150918 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03143829 0,08142144 ! glycine catabolic process GO:0006546 13 8 0,000 0,03143829 0,08133389 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03143829 0,08124653 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03143829 0,08115935 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03143829 0,08107237 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03143829 0,08098556 ! melanin metabolic process GO:0006582 15 8 0,000 0,03143829 0,08089895 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03143829 0,08081252 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03143829 0,08072627 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03143829 0,08064021 ! macrophage activation GO:0042116 12 8 0,000 0,03143829 0,08055433 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03143829 0,08046864 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03143829 0,08038312 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03143829 0,08029779 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03143829 0,08021264 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03143829 0,08012767 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03143829 0,08004288 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03143829 0,07995826 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03143829 0,07987383 ! osteoblast development GO:0002076 16 8 0,000 0,03143829 0,07978958 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03143829 0,0797055 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03143829 0,0796216 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03143829 0,07953787 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03143829 0,07945433 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03143829 0,07937095 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03143829 0,07928775 ! response to UV-B GO:0010224 16 8 0,000 0,03143829 0,07920473 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03143829 0,07912188 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03143829 0,0790392 ! intermediate filament organization GO:0045109 12 8 0,000 0,03143829 0,0789567 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03143829 0,07887437 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03143829 0,07879221 ! cellular extravasation GO:0045123 12 8 0,000 0,03143829 0,07871022 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03143829 0,0786284 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03143829 0,07854675 ! response to antibiotic GO:0046677 11 8 0,000 0,03143829 0,07846527 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03143829 0,07838396 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03143829 0,07830281 ! DNA topological change GO:0006265 12 8 0,000 0,03143829 0,07822184 ! response to tropane GO:0014073 15 8 0,000 0,03143829 0,07814103 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03143829 0,07806039 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,03143829 0,07797991 ! melanosome transport GO:0032402 13 8 0,000 0,03143829 0,07789961 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03143829 0,07781946 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03143829 0,07773948 ! mast cell activation GO:0045576 14 8 0,000 0,03143829 0,07765967 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03143829 0,07758002 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03143829 0,07750053 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03143829 0,07742121 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03143829 0,07734204 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03143829 0,07726304 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03143829 0,0771842 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03143829 0,07710552 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03143829 0,077027 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03143829 0,07694864 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03143829 0,07687044 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03143829 0,0767924 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03143829 0,07671452 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03143829 0,0766368 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03143829 0,07655923 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03143829 0,07648182 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03143829 0,07640456 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03143829 0,07632746 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03143829 0,07625052 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03143829 0,07617373 ! hormone catabolic process GO:0042447 17 8 0,000 0,03143829 0,0760971 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03143829 0,07602062 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03143829 0,07594429 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03143829 0,07586812 ! ATP catabolic process GO:0006200 11 8 0,000 0,03143829 0,0757921 ! blastocyst growth GO:0001832 19 8 0,000 0,03143829 0,07571623 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03143829 0,07564052 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03143829 0,07556495 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03143829 0,07548954 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03143829 0,07541427 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03143829 0,07533916 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03143829 0,0752642 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03143829 0,07518938 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03143829 0,07511471 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03143829 0,0750402 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03143829 0,07496583 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03143829 0,0748916 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03143829 0,07481752 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03143829 0,07474359 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03143829 0,07466981 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03143829 0,07459617 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03143829 0,07452268 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03143829 0,07444933 ! respiratory tube development GO:0030323 150 70 1,000 0,03188506 0,07543308 ! reproductive structure development GO:0048608 113 71 1,000 0,03272536 0,077345 ! B cell activation GO:0042113 160 71 1,000 0,03272536 0,0772691 ! regulation of caspase activity GO:0043281 122 72 1,000 0,03357432 0,07919589 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03357432 0,07911832 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,03357432 0,07904091 ! respiratory system development GO:0060541 153 72 1,000 0,03357432 0,07896365 ! learning or memory GO:0007611 147 73 1,000 0,03443185 0,08090141 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03529789 0,08285533 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,03529789 0,08277457 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,03529789 0,08269398 ! organelle localization GO:0051640 136 74 1,000 0,03529789 0,08261353 ! axon extension GO:0048675 15 9 0,000 0,03529851 0,0825347 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03529851 0,08245457 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03529851 0,0823746 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03529851 0,08229478 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03529851 0,08221511 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03529851 0,0821356 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03529851 0,08205624 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03529851 0,08197704 ! phosphate transport GO:0006817 19 9 0,000 0,03529851 0,08189798 ! reproductive behavior GO:0019098 19 9 0,000 0,03529851 0,08181908 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03529851 0,08174034 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03529851 0,08166174 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03529851 0,0815833 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03529851 0,081505 ! GTP metabolic process GO:0046039 9 9 0,000 0,03529851 0,08142686 ! RNA methylation GO:0001510 15 9 0,000 0,03529851 0,08134886 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03529851 0,08127101 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03529851 0,08119332 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03529851 0,08111577 ! artery development GO:0060840 24 9 0,000 0,03529851 0,08103837 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03529851 0,08096112 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03529851 0,08088401 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03529851 0,08080705 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03529851 0,08073024 ! chemosensory behavior GO:0007635 20 9 0,000 0,03529851 0,08065357 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03529851 0,08057705 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03529851 0,08050067 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03529851 0,08042444 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03529851 0,08034835 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03529851 0,08027241 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03529851 0,08019661 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03529851 0,08012095 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03529851 0,08004544 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03529851 0,07997007 ! protein targeting to ER GO:0045047 22 9 0,000 0,03529851 0,07989484 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03529851 0,07981975 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03529851 0,0797448 ! T cell selection GO:0045058 23 9 0,000 0,03529851 0,07966999 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03529851 0,07959532 ! endosome organization GO:0007032 17 9 0,000 0,03529851 0,0795208 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03529851 0,07944641 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03529851 0,07937216 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03529851 0,07929805 ! mannose metabolic process GO:0006013 13 9 0,000 0,03529851 0,07922408 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03529851 0,07915024 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03529851 0,07907655 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03529851 0,07900299 ! receptor clustering GO:0043113 18 9 0,000 0,03529851 0,07892956 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03529851 0,07885628 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03529851 0,07878313 ! ruffle organization GO:0031529 15 9 0,000 0,03529851 0,07871011 ! retinol metabolic process GO:0042572 18 9 0,000 0,03529851 0,07863723 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03529851 0,07856449 ! behavioral fear response GO:0001662 22 9 0,000 0,03529851 0,07849188 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03529851 0,0784194 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03529851 0,07834706 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03529851 0,07827485 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03529851 0,07820277 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03529851 0,07813083 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03529851 0,07805902 ! segment specification GO:0007379 13 9 0,000 0,03529851 0,07798734 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03529851 0,07791579 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03529851 0,07784437 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03529851 0,07777309 ! response to amine stimulus GO:0014075 13 9 0,000 0,03529851 0,07770193 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03529851 0,07763091 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03529851 0,07756001 ! erythrocyte development GO:0048821 15 9 0,000 0,03529851 0,07748924 ! gas homeostasis GO:0033483 16 9 0,000 0,03529851 0,07741861 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03529851 0,0773481 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03529851 0,07727772 ! renal water homeostasis GO:0003091 14 9 0,000 0,03529851 0,07720746 ! postreplication repair GO:0006301 22 9 0,000 0,03529851 0,07713734 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03529851 0,07706734 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03529851 0,07699747 ! icosanoid secretion GO:0032309 15 9 0,000 0,03529851 0,07692773 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03529851 0,07685811 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03529851 0,07678862 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03529851 0,07671925 ! regulation of cell division GO:0051302 15 9 0,000 0,03529851 0,07665001 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03529851 0,07658089 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03529851 0,0765119 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03529851 0,07644303 ! sterol catabolic process GO:0016127 11 9 0,000 0,03529851 0,07637429 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03529851 0,07630567 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03529851 0,07623717 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03529851 0,0761688 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03529851 0,07610055 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03529851 0,07603242 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03529851 0,07596441 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03529851 0,07589652 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03529851 0,07582876 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03529851 0,07576112 ! purine base metabolic process GO:0006144 21 9 0,000 0,03529851 0,07569359 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03529851 0,07562619 ! pigment granule transport GO:0051904 17 9 0,000 0,03529851 0,07555891 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03529851 0,07549174 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03529851 0,0754247 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03529851 0,07535777 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03529851 0,07529097 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03529851 0,07522428 ! mitochondrion localization GO:0051646 15 9 0,000 0,03529851 0,07515771 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,03617233 0,07695016 ! meiotic cell cycle GO:0051321 122 75 1,000 0,03617233 0,07688218 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,03705511 0,07868897 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,03884537 0,08241796 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03914347 0,08297726 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03914347 0,08290422 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03914347 0,0828313 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03914347 0,08275852 ! synapsis GO:0007129 13 10 0,000 0,03914347 0,08268586 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03914347 0,08261333 ! N-glycan processing GO:0006491 20 10 0,000 0,03914347 0,08254092 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03914347 0,08246865 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03914347 0,08239649 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03914347 0,08232447 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03914347 0,08225257 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03914347 0,0821808 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03914347 0,08210915 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03914347 0,08203763 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03914347 0,08196623 ! androgen metabolic process GO:0008209 17 10 0,000 0,03914347 0,08189495 ! phospholipid efflux GO:0033700 16 10 0,000 0,03914347 0,0818238 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03914347 0,08175277 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03914347 0,08168187 ! lung alveolus development GO:0048286 26 10 0,000 0,03914347 0,08161109 ! pathogenesis GO:0009405 13 10 0,000 0,03914347 0,08154043 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03914347 0,08146989 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03914347 0,08139948 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03914347 0,08132918 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03914347 0,08125901 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03914347 0,08118896 ! endoderm development GO:0007492 16 10 0,000 0,03914347 0,08111903 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03914347 0,08104922 ! arginine catabolic process GO:0006527 13 10 0,000 0,03914347 0,08097953 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03914347 0,08090996 ! proline metabolic process GO:0006560 13 10 0,000 0,03914347 0,08084051 ! L-serine metabolic process GO:0006563 18 10 0,000 0,03914347 0,08077118 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03914347 0,08070197 ! V(D)J recombination GO:0033151 28 10 0,000 0,03914347 0,08063287 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03914347 0,0805639 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03914347 0,08049504 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03914347 0,0804263 ! B cell proliferation GO:0042100 18 10 0,000 0,03914347 0,08035767 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03914347 0,08028917 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03914347 0,08022078 ! multicellular organism growth GO:0035264 18 10 0,000 0,03914347 0,08015251 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03914347 0,08008435 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03914347 0,08001631 ! epithelial cell development GO:0002064 20 10 0,000 0,03914347 0,07994838 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03914347 0,07988057 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03914347 0,07981288 ! macroautophagy GO:0016236 17 10 0,000 0,03914347 0,0797453 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03914347 0,07967783 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03914347 0,07961048 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03914347 0,07954324 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03914347 0,07947611 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03914347 0,0794091 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03914347 0,0793422 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03914347 0,07927542 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03914347 0,07920874 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03914347 0,07914218 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03914347 0,07907573 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03914347 0,07900939 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03914347 0,07894316 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03914347 0,07887705 ! response to dsRNA GO:0043331 20 10 0,000 0,03914347 0,07881104 ! DNA ligation GO:0006266 19 10 0,000 0,03914347 0,07874515 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03914347 0,07867936 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03914347 0,07861368 ! melanosome localization GO:0032400 16 10 0,000 0,03914347 0,07854812 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03914347 0,07848266 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03914347 0,07841731 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03914347 0,07835207 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03914347 0,07828694 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03914347 0,07822192 ! mRNA cleavage GO:0006379 17 10 0,000 0,03914347 0,07815701 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03914347 0,0780922 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03914347 0,0780275 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03914347 0,07796291 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03914347 0,07789842 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03914347 0,07783404 ! salivary gland development GO:0007431 27 10 0,000 0,03914347 0,07776977 ! prophase GO:0051324 15 10 0,000 0,03914347 0,07770561 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03914347 0,07764154 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03914347 0,07757759 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03914347 0,07751374 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03914347 0,07744999 ! midbrain development GO:0030901 13 10 0,000 0,03914347 0,07738635 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03914347 0,07732282 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03914347 0,07725939 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03914347 0,07719606 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03914347 0,07713284 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03914347 0,07706972 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03914347 0,0770067 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03914347 0,07694379 ! detection of calcium ion GO:0005513 23 10 0,000 0,03914347 0,07688097 ! oocyte development GO:0048599 17 10 0,000 0,03914347 0,07681827 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03914347 0,07675566 ! blastocyst formation GO:0001825 17 10 0,000 0,03914347 0,07669315 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03914347 0,07663075 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03914347 0,07656845 ! activation of innate immune response GO:0002218 12 10 0,000 0,03914347 0,07650625 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03914347 0,07644415 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03914347 0,07638215 ! response to nicotine GO:0035094 20 10 0,000 0,03914347 0,07632025 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03914347 0,07625846 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03914347 0,07619676 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03914347 0,07613516 ! localization within membrane GO:0051668 20 10 0,000 0,03914347 0,07607366 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,03975269 0,07719529 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,03975269 0,07713304 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,03975269 0,07707088 ! muscle cell differentiation GO:0042692 159 80 1,000 0,04066803 0,07878202 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,04159131 0,08050579 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,04159131 0,08044108 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,04159131 0,08037646 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04297324 0,08298043 ! respiratory burst GO:0045730 17 11 0,000 0,04297324 0,08291388 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04297324 0,08284745 ! neuron fate specification GO:0048665 17 11 0,000 0,04297324 0,08278111 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04297324 0,08271489 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04297324 0,08264877 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04297324 0,08258276 ! thyroid gland development GO:0030878 26 11 0,000 0,04297324 0,08251685 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04297324 0,08245105 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04297324 0,08238535 ! response to pain GO:0048265 24 11 0,000 0,04297324 0,08231975 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04297324 0,08225427 ! T cell proliferation GO:0042098 26 11 0,000 0,04297324 0,08218888 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04297324 0,0821236 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04297324 0,08205842 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04297324 0,08199335 ! bone resorption GO:0045453 16 11 0,000 0,04297324 0,08192838 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04297324 0,08186351 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04297324 0,08179874 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04297324 0,08173408 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04297324 0,08166952 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04297324 0,08160506 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04297324 0,0815407 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04297324 0,08147645 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04297324 0,08141229 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04297324 0,08134824 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,04297324 0,08128429 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04297324 0,08122043 ! UV protection GO:0009650 19 11 0,000 0,04297324 0,08115668 ! adult heart development GO:0007512 14 11 0,000 0,04297324 0,08109303 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04297324 0,08102948 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04297324 0,08096602 ! temperature homeostasis GO:0001659 17 11 0,000 0,04297324 0,08090267 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04297324 0,08083942 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04297324 0,08077626 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04297324 0,0807132 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04297324 0,08065024 ! regulation of organ growth GO:0046620 13 11 0,000 0,04297324 0,08058738 ! pigment granule localization GO:0051875 20 11 0,000 0,04297324 0,08052462 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04297324 0,08046196 ! vasoconstriction GO:0042310 18 11 0,000 0,04297324 0,08039939 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04297324 0,08033692 ! embryonic axis specification GO:0000578 18 11 0,000 0,04297324 0,08027454 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04297324 0,08021227 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04297324 0,08015009 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04297324 0,080088 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04297324 0,08002602 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04297324 0,07996412 ! zymogen activation GO:0031638 15 11 0,000 0,04297324 0,07990233 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04297324 0,07984063 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04297324 0,07977902 ! nucleosome positioning GO:0016584 15 11 0,000 0,04297324 0,07971751 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04297324 0,0796561 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04297324 0,07959477 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04297324 0,07953355 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04297324 0,07947242 ! acid secretion GO:0046717 18 11 0,000 0,04297324 0,07941138 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04297324 0,07935043 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04297324 0,07928958 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04297324 0,07922882 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04297324 0,07916816 ! oocyte differentiation GO:0009994 18 11 0,000 0,04297324 0,07910758 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04297324 0,0790471 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04297324 0,07898672 ! cholesterol efflux GO:0033344 19 11 0,000 0,04297324 0,07892642 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04297324 0,07886622 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04297324 0,07880611 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04297324 0,07874609 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04297324 0,07868616 ! embryonic gut development GO:0048566 15 11 0,000 0,04297324 0,07862632 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04297324 0,07856657 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04297324 0,07850692 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04297324 0,07844735 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04297324 0,07838788 ! defense response to fungus GO:0050832 13 11 0,000 0,04297324 0,07832849 ! developmental induction GO:0031128 19 11 0,000 0,04297324 0,0782692 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04297324 0,07820999 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04297324 0,07815088 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04297324 0,07809185 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04297324 0,07803291 ! nucleus localization GO:0051647 19 11 0,000 0,04297324 0,07797407 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04297324 0,07791531 ! response to oxygen levels GO:0070482 176 83 1,000 0,04346141 0,07874108 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,04536238 0,08212331 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04678787 0,08464031 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04678787 0,08457672 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04678787 0,08451322 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04678787 0,08444982 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04678787 0,08438651 ! cartilage condensation GO:0001502 20 12 0,000 0,04678787 0,0843233 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04678787 0,08426019 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04678787 0,08419716 ! protein complex disassembly GO:0043241 27 12 0,000 0,04678787 0,08413424 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04678787 0,0840714 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04678787 0,08400866 ! hippocampus development GO:0021766 26 12 0,000 0,04678787 0,08394602 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,04678787 0,08388346 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04678787 0,083821 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04678787 0,08375864 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04678787 0,08369636 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04678787 0,08363418 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04678787 0,08357209 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04678787 0,0835101 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04678787 0,08344819 ! drug transport GO:0015893 16 12 0,000 0,04678787 0,08338638 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04678787 0,08332465 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04678787 0,08326302 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04678787 0,08320148 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04678787 0,08314004 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04678787 0,08307868 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04678787 0,08301741 ! forebrain cell migration GO:0021885 21 12 0,000 0,04678787 0,08295623 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04678787 0,08289515 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04678787 0,08283415 ! fear response GO:0042596 26 12 0,000 0,04678787 0,08277324 ! monoamine transport GO:0015844 18 12 0,000 0,04678787 0,08271242 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04678787 0,0826517 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04678787 0,08259106 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04678787 0,08253051 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04678787 0,08247004 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04678787 0,08240967 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04678787 0,08234938 ! protein homotetramerization GO:0051289 21 12 0,000 0,04678787 0,08228919 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04678787 0,08222908 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04678787 0,08216906 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04678787 0,08210912 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04678787 0,08204928 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04678787 0,08198952 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04678787 0,08192985 ! cranial nerve development GO:0021545 20 12 0,000 0,04678787 0,08187026 ! fucose catabolic process GO:0019317 22 12 0,000 0,04678787 0,08181076 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04678787 0,08175135 ! histone methylation GO:0016571 26 12 0,000 0,04678787 0,08169202 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04678787 0,08163278 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04678787 0,08157363 ! gland morphogenesis GO:0022612 29 12 0,000 0,04678787 0,08151456 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04678787 0,08145558 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04678787 0,08139668 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04678787 0,08133787 ! spleen development GO:0048536 22 12 0,000 0,04678787 0,08127914 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04678787 0,0812205 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04678787 0,08116194 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04678787 0,08110346 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04678787 0,08104507 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04678787 0,08098677 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04678787 0,08092855 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04678787 0,08087041 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04678787 0,08081235 ! response to cold GO:0009409 17 12 0,000 0,04678787 0,08075438 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04678787 0,08069649 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04678787 0,08063869 ! regulation of protein transport GO:0051223 154 87 1,000 0,04729361 0,08145198 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,04827039 0,08307479 ! regulation of DNA binding GO:0051101 155 88 1,000 0,04827039 0,08301541 ! regulation of neurological system process GO:0031644 148 88 1,000 0,04827039 0,08295611 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,04925451 0,08458698 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,04925451 0,08452665 ! sex differentiation GO:0007548 145 90 1,000 0,05024591 0,08616654 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05058742 0,0866904 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05058742 0,0866287 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05058742 0,08656709 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05058742 0,08650556 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05058742 0,08644412 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05058742 0,08638277 ! lipid localization GO:0010876 28 13 0,000 0,05058742 0,08632151 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05058742 0,08626033 ! organelle fusion GO:0048284 32 13 0,000 0,05058742 0,08619924 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05058742 0,08613824 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05058742 0,08607732 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05058742 0,08601649 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05058742 0,08595574 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05058742 0,08589508 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05058742 0,0858345 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05058742 0,08577401 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05058742 0,08571361 ! methionine metabolic process GO:0006555 27 13 0,000 0,05058742 0,08565329 ! plasma membrane organization GO:0007009 24 13 0,000 0,05058742 0,08559306 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05058742 0,08553291 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05058742 0,08547284 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05058742 0,08541286 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05058742 0,08535296 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05058742 0,08529315 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05058742 0,08523342 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05058742 0,08517378 ! exocrine system development GO:0035272 32 13 0,000 0,05058742 0,08511421 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05058742 0,08505474 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05058742 0,08499534 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05058742 0,08493603 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05058742 0,0848768 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05058742 0,08481765 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05058742 0,08475858 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05058742 0,0846996 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05058742 0,0846407 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05058742 0,08458188 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05058742 0,08452314 ! ribosome assembly GO:0042255 17 13 0,000 0,05058742 0,08446449 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05058742 0,08440591 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05058742 0,08434742 ! chromatin silencing GO:0006342 26 13 0,000 0,05058742 0,08428901 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05058742 0,08423068 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05058742 0,08417242 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05058742 0,08411425 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05058742 0,08405616 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05058742 0,08399815 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05058742 0,08394023 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05058742 0,08388238 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05058742 0,0838246 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05058742 0,08376691 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05058742 0,0837093 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05058742 0,08365177 ! embryonic placenta development GO:0001892 23 13 0,000 0,05058742 0,08359432 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05058742 0,08353694 ! insulin secretion GO:0030073 23 13 0,000 0,05058742 0,08347965 ! actin filament polymerization GO:0030041 24 13 0,000 0,05058742 0,08342243 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05058742 0,08336529 ! acrosome reaction GO:0007340 18 13 0,000 0,05058742 0,08330823 ! regulation of defense response GO:0031347 149 92 1,000 0,05225023 0,08598773 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,05326301 0,08759454 ! regulation of membrane potential GO:0042391 164 93 1,000 0,05326301 0,0875347 ! rRNA transcription GO:0009303 25 14 0,000 0,05437195 0,08929618 ! lactation GO:0007595 26 14 0,000 0,05437195 0,08923527 ! reproductive cellular process GO:0048610 20 14 0,000 0,05437195 0,08917444 ! tRNA modification GO:0006400 20 14 0,000 0,05437195 0,0891137 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05437195 0,08905303 ! regulation of S phase GO:0033261 23 14 0,000 0,05437195 0,08899245 ! water transport GO:0006833 21 14 0,000 0,05437195 0,08893196 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05437195 0,08887154 ! non-recombinational repair GO:0000726 25 14 0,000 0,05437195 0,08881121 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05437195 0,08875095 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05437195 0,08869078 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05437195 0,0886307 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05437195 0,08857069 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05437195 0,08851076 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05437195 0,08845092 ! palate development GO:0060021 31 14 0,000 0,05437195 0,08839115 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05437195 0,08833147 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05437195 0,08827187 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05437195 0,08821234 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05437195 0,0881529 ! arginine metabolic process GO:0006525 17 14 0,000 0,05437195 0,08809354 ! regulation of heart rate GO:0002027 24 14 0,000 0,05437195 0,08803426 ! organic alcohol transport GO:0015850 29 14 0,000 0,05437195 0,08797506 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05437195 0,08791593 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05437195 0,08785689 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05437195 0,08779792 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05437195 0,08773904 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05437195 0,08768023 ! L-amino acid transport GO:0015807 30 14 0,000 0,05437195 0,08762151 ! bone mineralization GO:0030282 17 14 0,000 0,05437195 0,08756286 ! stem cell development GO:0048864 43 14 0,000 0,05437195 0,08750429 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05437195 0,08744579 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05437195 0,08738738 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05437195 0,08732904 ! cerebellum development GO:0021549 21 14 0,000 0,05437195 0,08727079 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05437195 0,0872126 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05437195 0,0871545 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05437195 0,08709648 ! cofactor transport GO:0051181 26 14 0,000 0,05437195 0,08703853 ! NADP metabolic process GO:0006739 24 14 0,000 0,05437195 0,08698066 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05437195 0,08692286 ! intestinal absorption GO:0050892 25 14 0,000 0,05437195 0,08686514 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05437195 0,0868075 ! oxygen transport GO:0015671 21 14 0,000 0,05437195 0,08674994 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05437195 0,08669245 ! male genitalia development GO:0030539 24 14 0,000 0,05437195 0,08663504 ! regulation of axon extension GO:0030516 37 14 0,000 0,05437195 0,0865777 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05437195 0,08652044 ! forebrain development GO:0030900 188 95 1,000 0,05530946 0,0879541 ! protein ubiquitination GO:0016567 217 97 1,000 0,05738328 0,09119165 ! regulation of protein localization GO:0032880 176 97 1,000 0,05738328 0,09113146 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05814152 0,09227473 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05814152 0,0922139 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05814152 0,09215316 ! superoxide anion generation GO:0042554 20 15 0,000 0,05814152 0,09209249 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,05814152 0,0920319 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05814152 0,0919714 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05814152 0,09191097 ! copper ion transport GO:0006825 20 15 0,000 0,05814152 0,09185062 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05814152 0,09179035 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05814152 0,09173016 ! sulfate transport GO:0008272 23 15 0,000 0,05814152 0,09167005 ! response to cAMP GO:0051591 22 15 0,000 0,05814152 0,09161001 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05814152 0,09155006 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05814152 0,09149018 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05814152 0,09143039 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05814152 0,09137067 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05814152 0,09131103 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05814152 0,09125146 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05814152 0,09119198 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05814152 0,09113257 ! pituitary gland development GO:0021983 29 15 0,000 0,05814152 0,09107324 ! vesicle coating GO:0006901 33 15 0,000 0,05814152 0,09101398 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05814152 0,09095481 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05814152 0,09089571 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05814152 0,09083668 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05814152 0,09077774 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05814152 0,09071887 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05814152 0,09066007 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05814152 0,09060136 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05814152 0,09054271 ! histone deacetylation GO:0016575 20 15 0,000 0,05814152 0,09048415 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05814152 0,09042566 ! tissue regeneration GO:0042246 26 15 0,000 0,05814152 0,09036724 ! water homeostasis GO:0030104 27 15 0,000 0,05814152 0,0903089 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05814152 0,09025064 ! muscle maintenance GO:0046716 26 15 0,000 0,05814152 0,09019245 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05814152 0,09013434 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05814152 0,0900763 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05814152 0,09001833 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05814152 0,08996045 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05814152 0,08990263 ! cell killing GO:0001906 29 15 0,000 0,05814152 0,08984489 ! detection of bacterium GO:0016045 18 15 0,000 0,05814152 0,08978722 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05814152 0,08972963 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05814152 0,08967211 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05814152 0,08961467 ! peptide hormone processing GO:0016486 23 15 0,000 0,05814152 0,08955729 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06189619 0,09527973 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06189619 0,09521881 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06189619 0,09515797 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06189619 0,09509721 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06189619 0,09503652 ! bone remodeling GO:0046849 27 16 0,000 0,06189619 0,09497591 ! filopodium assembly GO:0046847 32 16 0,000 0,06189619 0,09491538 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06189619 0,09485492 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06189619 0,09479454 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06189619 0,09473424 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06189619 0,09467401 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06189619 0,09461387 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06189619 0,09455379 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06189619 0,0944938 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06189619 0,09443388 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06189619 0,09437403 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06189619 0,09431426 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06189619 0,09425457 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06189619 0,09419496 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06189619 0,09413541 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06189619 0,09407595 ! response to osmotic stress GO:0006970 25 16 0,000 0,06189619 0,09401656 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06189619 0,09395724 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06189619 0,093898 ! fructose metabolic process GO:0006000 25 16 0,000 0,06189619 0,09383883 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06189619 0,09377974 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06189619 0,09372072 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06189619 0,09366178 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06189619 0,09360291 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06189619 0,09354411 ! axon cargo transport GO:0008088 43 16 0,000 0,06189619 0,09348539 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06189619 0,09342674 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06189619 0,09336817 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06189619 0,09330966 ! neuron recognition GO:0008038 35 16 0,000 0,06189619 0,09325124 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06189619 0,09319288 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06189619 0,0931346 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06189619 0,09307639 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06189619 0,09301825 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06189619 0,09296019 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06189619 0,0929022 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06189619 0,09284428 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06189619 0,09278643 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06189619 0,09272866 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06189619 0,09267095 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06189619 0,09261332 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,06189619 0,09255576 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06563601 0,09808711 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06563601 0,09802622 ! metencephalon development GO:0022037 30 17 0,000 0,06563601 0,09796541 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06563601 0,09790468 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06563601 0,09784402 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06563601 0,09778343 ! signal complex assembly GO:0007172 41 17 0,000 0,06563601 0,09772292 ! endothelial cell migration GO:0043542 28 17 0,000 0,06563601 0,09766249 ! inositol metabolic process GO:0006020 28 17 0,000 0,06563601 0,09760213 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06563601 0,09754184 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06563601 0,09748163 ! glial cell development GO:0021782 27 17 0,000 0,06563601 0,09742149 ! limbic system development GO:0021761 36 17 0,000 0,06563601 0,09736143 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06563601 0,09730144 ! adult walking behavior GO:0007628 33 17 0,000 0,06563601 0,09724153 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06563601 0,09718169 ! heart looping GO:0001947 30 17 0,000 0,06563601 0,09712192 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06563601 0,09706223 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06563601 0,09700261 ! myoblast differentiation GO:0045445 45 17 0,000 0,06563601 0,09694306 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06563601 0,09688358 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06563601 0,09682418 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06563601 0,09676485 ! glycine metabolic process GO:0006544 28 17 0,000 0,06563601 0,0967056 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06563601 0,09664641 ! NAD metabolic process GO:0019674 29 17 0,000 0,06563601 0,0965873 ! membrane budding GO:0006900 37 17 0,000 0,06563601 0,09652827 ! DNA integration GO:0015074 29 17 0,000 0,06563601 0,0964693 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06563601 0,0964104 ! regulation of protein binding GO:0043393 33 17 0,000 0,06563601 0,09635158 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06563601 0,09629283 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06563601 0,09623415 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06563601 0,09617554 ! genitalia development GO:0048806 30 17 0,000 0,06563601 0,09611701 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,06563601 0,09605854 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06563601 0,09600015 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06563601 0,09594182 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06563601 0,09588357 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06563601 0,09582539 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06563601 0,09576728 ! steroid catabolic process GO:0006706 31 17 0,000 0,06563601 0,09570924 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06563601 0,09565127 ! gas transport GO:0015669 25 17 0,000 0,06563601 0,09559337 ! organic cation transport GO:0015695 31 17 0,000 0,06563601 0,09553554 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06563601 0,09547778 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06563601 0,09542009 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06563601 0,09536246 ! microspike assembly GO:0030035 36 17 0,000 0,06563601 0,09530491 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06563601 0,09524743 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06563601 0,09519002 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06936105 0,10053174 ! neuron maturation GO:0042551 42 18 0,000 0,06936105 0,10047121 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06936105 0,10041076 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06936105 0,10035038 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06936105 0,10029008 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06936105 0,10022984 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06936105 0,10016968 ! memory GO:0007613 31 18 0,000 0,06936105 0,10010959 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06936105 0,10004957 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06936105 0,09998963 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06936105 0,09992975 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06936105 0,09986995 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06936105 0,09981022 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06936105 0,09975056 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06936105 0,09969097 ! response to retinoic acid GO:0032526 26 18 0,000 0,06936105 0,09963145 ! response to fungus GO:0009620 21 18 0,000 0,06936105 0,09957201 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06936105 0,09951263 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06936105 0,09945333 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06936105 0,0993941 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06936105 0,09933493 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06936105 0,09927584 ! vitamin transport GO:0051180 27 18 0,000 0,06936105 0,09921682 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06936105 0,09915786 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06936105 0,09909898 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06936105 0,09904017 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06936105 0,09898143 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06936105 0,09892275 ! nerve development GO:0021675 28 18 0,000 0,06936105 0,09886415 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06936105 0,09880562 ! protein secretion GO:0009306 39 19 0,000 0,07307136 0,10402941 ! positive regulation of translation GO:0045727 30 19 0,000 0,07307136 0,10396789 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,07307136 0,10390644 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,07307136 0,10384507 ! skin development GO:0043588 36 19 0,000 0,07307136 0,10378376 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07307136 0,10372253 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07307136 0,10366138 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07307136 0,10360029 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07307136 0,10353928 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07307136 0,10347834 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07307136 0,10341747 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,07307136 0,10335667 ! cerebral cortex development GO:0021987 36 19 0,000 0,07307136 0,10329594 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,07307136 0,10323529 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,07307136 0,1031747 ! heme metabolic process GO:0042168 36 19 0,000 0,07307136 0,10311419 ! neuromuscular junction development GO:0007528 34 19 0,000 0,07307136 0,10305375 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07307136 0,10299338 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07307136 0,10293308 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,07307136 0,10287285 ! peptide cross-linking GO:0018149 37 19 0,000 0,07307136 0,10281269 ! protein export from nucleus GO:0006611 36 19 0,000 0,07307136 0,1027526 ! heart process GO:0003015 30 19 0,000 0,07307136 0,10269258 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07307136 0,10263263 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07307136 0,10257275 ! visual learning GO:0008542 36 19 0,000 0,07307136 0,10251294 ! G1 phase GO:0051318 40 19 0,000 0,07307136 0,1024532 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07307136 0,10239353 ! cell-cell junction organization GO:0045216 35 19 0,000 0,07307136 0,10233393 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07307136 0,1022744 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07307136 0,10221494 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07307136 0,10215555 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07307136 0,10209622 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07307136 0,10203697 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07307136 0,10197778 ! cilium assembly GO:0042384 37 19 0,000 0,07307136 0,10191866 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07307136 0,10185962 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,076767 0,10694928 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,076767 0,10688739 ! positive regulation of ossification GO:0045778 47 20 0,000 0,076767 0,10682557 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,076767 0,10676382 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,076767 0,10670214 ! cAMP metabolic process GO:0046058 36 20 0,000 0,076767 0,10664054 ! response to vitamin GO:0033273 31 20 0,000 0,076767 0,106579 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,076767 0,10651754 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,076767 0,10645614 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,076767 0,10639482 ! response to alkaloid GO:0043279 38 20 0,000 0,076767 0,10633357 ! retinoid metabolic process GO:0001523 32 20 0,000 0,076767 0,10627239 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,076767 0,10621128 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,076767 0,10615024 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,076767 0,10608927 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,076767 0,10602836 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,076767 0,10596753 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,076767 0,10590677 ! body fluid secretion GO:0007589 31 20 0,000 0,076767 0,10584608 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,076767 0,10578546 ! peptide secretion GO:0002790 35 20 0,000 0,076767 0,10572491 ! stem cell differentiation GO:0048863 53 20 0,000 0,076767 0,10566442 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,076767 0,10560401 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,076767 0,10554366 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,076767 0,10548339 ! sensory perception of pain GO:0019233 30 20 0,000 0,076767 0,10542318 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,076767 0,10536304 ! diencephalon development GO:0021536 34 20 0,000 0,076767 0,10530297 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,076767 0,10524297 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,076767 0,10518304 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,076767 0,10512317 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,076767 0,10506337 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,076767 0,10500364 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,076767 0,10494398 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,076767 0,10488439 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,076767 0,10482486 ! regulation of glucose import GO:0046324 29 20 0,000 0,076767 0,10476541 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,076767 0,10470602 ! actin filament-based movement GO:0030048 43 20 0,000 0,076767 0,10464669 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,076767 0,10458744 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,076767 0,10452825 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,076767 0,10446912 ! negative regulation of translation GO:0017148 29 20 0,000 0,076767 0,10441007 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,076767 0,10435108 ! regulation of cell killing GO:0031341 42 21 0,000 0,08044803 0,10929304 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08044803 0,10923136 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08044803 0,10916975 ! hormone secretion GO:0046879 38 21 0,000 0,08044803 0,10910821 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08044803 0,10904674 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08044803 0,10898534 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08044803 0,10892401 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08044803 0,10886275 ! axis specification GO:0009798 38 21 0,000 0,08044803 0,10880156 ! ovarian follicle development GO:0001541 35 21 0,000 0,08044803 0,10874043 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08044803 0,10867938 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08044803 0,10861839 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08044803 0,10855747 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,08044803 0,10849662 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08044803 0,10843584 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08044803 0,10837512 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08044803 0,10831448 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,08044803 0,1082539 ! cytolysis GO:0019835 24 21 0,000 0,08044803 0,10819339 ! vasodilation GO:0042311 39 21 0,000 0,08044803 0,10813294 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08044803 0,10807257 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08044803 0,10801226 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08044803 0,10795202 ! oogenesis GO:0048477 36 21 0,000 0,08044803 0,10789184 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08044803 0,10783174 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,08044803 0,1077717 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08044803 0,10771172 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08044803 0,10765182 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,08044803 0,10759198 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08044803 0,10753221 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08044803 0,1074725 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08044803 0,10741286 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08044803 0,10735328 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08044803 0,10729377 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08044803 0,10723433 ! collagen catabolic process GO:0030574 28 21 0,000 0,08044803 0,10717496 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08044803 0,10711564 ! gut development GO:0048565 39 21 0,000 0,08044803 0,1070564 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08411451 0,11187369 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08411451 0,11181188 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08411451 0,11175014 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,08411451 0,11168847 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,08411451 0,11162687 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08411451 0,11156533 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08411451 0,11150386 ! regeneration GO:0031099 41 22 0,000 0,08411451 0,11144246 ! keratinization GO:0031424 28 22 0,000 0,08411451 0,11138113 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,08411451 0,11131986 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08411451 0,11125866 ! sensory perception of taste GO:0050909 28 22 0,000 0,08411451 0,11119753 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,08411451 0,11113647 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08411451 0,11107547 ! vacuolar transport GO:0007034 36 22 0,000 0,08411451 0,11101454 ! lysosome organization GO:0007040 41 22 0,000 0,08411451 0,11095368 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08411451 0,11089288 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08411451 0,11083215 ! fucose metabolic process GO:0006004 39 22 0,000 0,08411451 0,11077149 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08411451 0,11071089 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,08411451 0,11065036 ! ureteric bud development GO:0001657 43 22 0,000 0,08411451 0,1105899 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08411451 0,1105295 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08411451 0,11046916 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08411451 0,1104089 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08411451 0,1103487 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08411451 0,11028856 ! sarcomere organization GO:0045214 30 22 0,000 0,08411451 0,11022849 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08411451 0,11016849 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08411451 0,11010855 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08411451 0,11004867 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08411451 0,10998886 ! protein stabilization GO:0050821 39 22 0,000 0,08411451 0,10992912 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,08776649 0,11463961 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,08776649 0,11457741 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,08776649 0,11451527 ! gluconeogenesis GO:0006094 33 23 0,000 0,08776649 0,11445321 ! viral genome replication GO:0019079 41 23 0,000 0,08776649 0,11439121 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,08776649 0,11432927 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,08776649 0,11426741 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,08776649 0,11420561 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,08776649 0,11414387 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,08776649 0,11408221 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,08776649 0,11402061 ! visual behavior GO:0007632 42 23 0,000 0,08776649 0,11395907 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,08776649 0,11389761 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,08776649 0,11383621 ! response to ethanol GO:0045471 46 23 0,000 0,08776649 0,11377487 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,08776649 0,11371361 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,08776649 0,1136524 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,08776649 0,11359127 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,08776649 0,1135302 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,08776649 0,11346919 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,08776649 0,11340825 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,08776649 0,11334738 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,08776649 0,11328657 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,08776649 0,11322583 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,08776649 0,11316515 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,08776649 0,11310453 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,08776649 0,11304399 ! fatty acid transport GO:0015908 44 23 0,000 0,08776649 0,1129835 ! platelet activation GO:0030168 37 23 0,000 0,08776649 0,11292308 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,08776649 0,11286273 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,08776649 0,11280244 ! hormone transport GO:0009914 40 23 0,000 0,08776649 0,11274221 ! cell-cell recognition GO:0009988 25 23 0,000 0,08776649 0,11268205 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,08776649 0,11262196 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,08776649 0,11256192 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,08776649 0,11250195 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,08776649 0,11244205 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,08776649 0,11238221 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09140402 0,1169777 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,09140402 0,11691551 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09140402 0,11685339 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09140402 0,11679133 ! vesicle docking GO:0048278 47 24 0,000 0,09140402 0,11672934 ! spinal cord development GO:0021510 47 24 0,000 0,09140402 0,11666742 ! vacuole organization GO:0007033 43 24 0,000 0,09140402 0,11660556 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,09140402 0,11654376 ! digestive system process GO:0022600 39 24 0,000 0,09140402 0,11648203 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09140402 0,11642037 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,09140402 0,11635877 ! regulation of behavior GO:0050795 43 24 0,000 0,09140402 0,11629724 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09140402 0,11623577 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,09140402 0,11617437 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09140402 0,11611303 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09140402 0,11605176 ! membrane depolarization GO:0051899 39 24 0,000 0,09140402 0,11599055 ! pallium development GO:0021543 49 24 0,000 0,09140402 0,1159294 ! pentose metabolic process GO:0019321 35 24 0,000 0,09140402 0,11586832 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09140402 0,11580731 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09140402 0,11574636 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09140402 0,11568547 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09140402 0,11562465 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09140402 0,11556389 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09140402 0,11550319 ! regulation of amine transport GO:0051952 40 24 0,000 0,09140402 0,11544256 ! myelination GO:0042552 45 25 0,000 0,09502717 0,1199556 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09502717 0,1198927 ! phototransduction GO:0007602 33 25 0,000 0,09502717 0,11982987 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09502717 0,11976709 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,09502717 0,11970439 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,09502717 0,11964175 ! receptor metabolic process GO:0043112 46 25 0,000 0,09502717 0,11957917 ! chromosome condensation GO:0030261 45 25 0,000 0,09502717 0,11951667 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09502717 0,11945422 ! neural crest cell development GO:0014032 54 25 0,000 0,09502717 0,11939184 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09502717 0,11932953 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,09502717 0,11926728 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,09502717 0,1192051 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09502717 0,11914298 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09502717 0,11908093 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09502717 0,11901894 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09502717 0,11895701 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09502717 0,11889515 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09502717 0,11883336 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,09502717 0,11877163 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09502717 0,11870996 ! telomere organization GO:0032200 43 25 0,000 0,09502717 0,11864836 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09502717 0,11858682 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09502717 0,11852534 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,098636 0,12296281 ! embryonic pattern specification GO:0009880 44 26 0,000 0,098636 0,12289913 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,098636 0,12283551 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,098636 0,12277197 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,098636 0,12270849 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,098636 0,12264507 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,098636 0,12258172 ! tube lumen formation GO:0035148 50 26 0,000 0,098636 0,12251844 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,098636 0,12245522 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,098636 0,12239206 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,098636 0,12232898 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,098636 0,12226595 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,098636 0,12220299 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,098636 0,1221401 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,098636 0,12207727 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,098636 0,12201451 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,098636 0,12195181 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,098636 0,12188917 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,098636 0,1218266 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,098636 0,12176409 ! blastocyst development GO:0001824 49 26 0,000 0,098636 0,12170165 ! leukocyte proliferation GO:0070661 52 26 0,000 0,098636 0,12163927 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,098636 0,12157695 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,098636 0,1215147 ! neuron fate commitment GO:0048663 48 27 0,000 0,10223055 0,12587856 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,10223055 0,12581417 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,10223055 0,12574985 ! iron ion transport GO:0006826 59 27 0,000 0,10223055 0,12568559 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,10223055 0,1256214 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,10223055 0,12555728 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10223055 0,12549322 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,10223055 0,12542922 ! fat cell differentiation GO:0045444 50 27 0,000 0,10223055 0,12536529 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10223055 0,12530143 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,10223055 0,12523763 ! autophagy GO:0006914 41 27 0,000 0,10223055 0,1251739 ! response to toxin GO:0009636 47 27 0,000 0,10223055 0,12511023 ! primary neural tube formation GO:0014020 51 27 0,000 0,10223055 0,12504662 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10223055 0,12498308 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10223055 0,12491961 ! glutathione metabolic process GO:0006749 39 27 0,000 0,10223055 0,1248562 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,10223055 0,12479285 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,10223055 0,12472957 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,10223055 0,12466635 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,10223055 0,1246032 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,10581089 0,12890177 ! circadian rhythm GO:0007623 50 28 0,000 0,10581089 0,12883654 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,10581089 0,12877137 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,10581089 0,12870627 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,10581089 0,12864123 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,10581089 0,12857626 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,10581089 0,12851136 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,10581089 0,12844652 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,10581089 0,12838174 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,10581089 0,12831703 ! synaptogenesis GO:0007416 42 28 0,000 0,10581089 0,12825239 ! lipid oxidation GO:0034440 43 28 0,000 0,10581089 0,12818781 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,10581089 0,1281233 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,10581089 0,12805885 ! translational initiation GO:0006413 65 29 0,000 0,10937707 0,13230831 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,10937707 0,13224182 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10937707 0,1321754 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10937707 0,13210905 ! catechol metabolic process GO:0009712 54 29 0,000 0,10937707 0,13204276 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10937707 0,13197654 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10937707 0,13191039 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10937707 0,1318443 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10937707 0,13177828 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10937707 0,13171232 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,10937707 0,13164643 ! cell fate determination GO:0001709 60 29 0,000 0,10937707 0,13158061 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10937707 0,13151485 ! detection of light stimulus GO:0009583 38 29 0,000 0,10937707 0,13144916 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,10937707 0,13138353 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,10937707 0,13131797 ! tissue homeostasis GO:0001894 48 29 0,000 0,10937707 0,13125248 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,10937707 0,13118705 ! phenol metabolic process GO:0018958 55 30 0,000 0,11292914 0,13537992 ! zinc ion transport GO:0006829 45 30 0,000 0,11292914 0,1353125 ! membrane docking GO:0022406 61 30 0,000 0,11292914 0,13524515 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,11292914 0,13517786 ! regulation of innate immune response GO:0045088 51 30 0,000 0,11292914 0,13511064 ! acute-phase response GO:0006953 49 30 0,000 0,11292914 0,13504349 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,11292914 0,13497641 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,11292914 0,13490939 ! phospholipid transport GO:0015914 51 30 0,000 0,11292914 0,13484243 ! ensheathment of neurons GO:0007272 57 30 0,000 0,11292914 0,13477555 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,11292914 0,13470873 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,11292914 0,13464197 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,11292914 0,13457529 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,11292914 0,13450867 ! eye morphogenesis GO:0048592 60 30 0,000 0,11292914 0,13444211 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11646716 0,13858555 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11646716 0,13851705 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11646716 0,13844861 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,11646716 0,13838024 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,11646716 0,13831194 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,11646716 0,1382437 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11646716 0,13817554 ! ovulation cycle process GO:0022602 49 31 0,000 0,11646716 0,13810744 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11646716 0,1380394 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,11646716 0,13797144 ! peptide transport GO:0015833 55 31 0,000 0,11646716 0,13790354 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,11646716 0,13783571 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,11646716 0,13776794 ! mesoderm formation GO:0001707 69 31 0,000 0,11646716 0,13770024 ! natural killer cell activation GO:0030101 45 31 0,000 0,11646716 0,13763261 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11646716 0,13756504 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11646716 0,13749754 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,11646716 0,13743011 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,11646716 0,13736274 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,11646716 0,13729544 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11999119 0,14138041 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11999119 0,14131121 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11999119 0,14124208 ! cholesterol transport GO:0030301 56 32 0,000 0,11999119 0,14117301 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11999119 0,14110401 ! spliceosome assembly GO:0000245 67 32 0,000 0,11999119 0,14103508 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11999119 0,14096621 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,11999119 0,14089741 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11999119 0,14082868 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,11999119 0,14076002 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11999119 0,14069142 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,11999119 0,14062289 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,11999119 0,14055443 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,11999119 0,14048604 ! ovulation cycle GO:0042698 51 32 0,000 0,11999119 0,14041771 ! peripheral nervous system development GO:0007422 64 32 0,000 0,11999119 0,14034944 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11999119 0,14028125 ! hindbrain development GO:0030902 61 32 0,000 0,11999119 0,14021311 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11999119 0,14014505 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11999119 0,14007705 ! gene silencing GO:0016458 65 32 0,000 0,11999119 0,14000912 ! post-embryonic development GO:0009791 69 33 0,000 0,12350128 0,14403494 ! protein targeting to membrane GO:0006612 68 33 0,000 0,12350128 0,14396515 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,12350128 0,14389544 ! ceramide metabolic process GO:0006672 64 33 0,000 0,12350128 0,14382579 ! formation of primary germ layer GO:0001704 72 33 0,000 0,12350128 0,14375621 ! cell fate specification GO:0001708 52 33 0,000 0,12350128 0,14368669 ! sterol transport GO:0015918 57 33 0,000 0,12350128 0,14361724 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,12350128 0,14354786 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,12350128 0,14347855 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,12350128 0,1434093 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,12350128 0,14334013 ! glial cell differentiation GO:0010001 63 34 0,000 0,12699749 0,14732688 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12699749 0,14725588 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,12699749 0,14718495 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,12699749 0,14711408 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,12699749 0,14704329 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,12699749 0,14697256 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,12699749 0,1469019 ! mismatch repair GO:0006298 46 34 0,000 0,12699749 0,14683131 ! spermatid development GO:0007286 63 34 0,000 0,12699749 0,14676078 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,12699749 0,14669033 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,12699749 0,14661994 ! regulation of muscle development GO:0048634 70 35 0,000 0,13047986 0,15056813 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,13047986 0,15049595 ! negative regulation of secretion GO:0051048 63 35 0,000 0,13047986 0,15042384 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,13047986 0,15035179 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,13047986 0,15027982 ! odontogenesis GO:0042476 66 35 0,000 0,13047986 0,15020792 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,13047986 0,15013608 ! female gonad development GO:0008585 58 35 0,000 0,13047986 0,15006431 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,13047986 0,14999262 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,13047986 0,14992099 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,13047986 0,14984942 ! cytokine production GO:0001816 59 35 0,000 0,13047986 0,14977793 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,13047986 0,14970651 ! neural tube formation GO:0001841 67 35 0,000 0,13047986 0,14963515 ! vesicle localization GO:0051648 64 35 0,000 0,13047986 0,14956386 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,13394846 0,15346666 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,13394846 0,15339362 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,13394846 0,15332065 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,13394846 0,15324774 ! positive regulation of cell development GO:0010720 80 36 0,000 0,13394846 0,1531749 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,13394846 0,15310214 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,13394846 0,15302944 ! aerobic respiration GO:0009060 55 36 0,000 0,13394846 0,15295681 ! embryonic organ development GO:0048568 57 36 0,000 0,13394846 0,15288425 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,13394846 0,15281176 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,13394846 0,15273933 ! RNA export from nucleus GO:0006405 56 37 0,000 0,13740334 0,15660466 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,13740334 0,15653051 ! organic anion transport GO:0015711 68 37 0,000 0,13740334 0,15645643 ! tissue remodeling GO:0048771 76 37 0,000 0,13740334 0,15638242 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,13740334 0,15630848 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13740334 0,15623461 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,13740334 0,15616081 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13740334 0,15608708 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,13740334 0,15601342 ! spermatid differentiation GO:0048515 66 37 0,000 0,13740334 0,15593983 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,14084455 0,15976991 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,14084455 0,15969462 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,14084455 0,1596194 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,14084455 0,15954425 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,14084455 0,15946917 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,14084455 0,15939416 ! lipid homeostasis GO:0055088 67 38 0,000 0,14084455 0,15931922 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,14084455 0,15924435 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,14084455 0,15916956 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,14084455 0,15909483 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,14084455 0,15902017 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,14084455 0,15894558 ! mRNA catabolic process GO:0006402 71 39 0,000 0,14427214 0,16273736 ! mammary gland development GO:0030879 86 39 0,000 0,14427214 0,1626611 ! learning GO:0007612 77 39 0,000 0,14427214 0,16258491 ! ear morphogenesis GO:0042471 60 39 0,000 0,14427214 0,16250879 ! organic ether metabolic process GO:0018904 55 39 0,000 0,14427214 0,16243275 ! ion transmembrane transport GO:0034220 66 39 0,000 0,14427214 0,16235677 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,14427214 0,16228087 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,14427214 0,16220504 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,14427214 0,16212928 ! RNA modification GO:0009451 57 39 0,000 0,14427214 0,16205359 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,14427214 0,16197797 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,14768618 0,16573365 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14768618 0,16565639 ! feeding behavior GO:0007631 59 40 0,000 0,14768618 0,16557919 ! negative regulation of binding GO:0051100 72 40 0,000 0,14768618 0,16550207 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,14768618 0,16542502 ! maintenance of protein location GO:0045185 91 40 0,000 0,14768618 0,16534804 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,15108671 0,16907657 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,15108671 0,16899796 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,15108671 0,16891943 ! gliogenesis GO:0042063 88 41 0,000 0,15108671 0,16884097 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,15108671 0,16876259 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,15108671 0,16868428 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,15108671 0,16860604 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,15108671 0,16852787 ! female gamete generation GO:0007292 61 41 0,000 0,15108671 0,16844978 ! polyol metabolic process GO:0019751 66 41 0,000 0,15108671 0,16837175 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,15108671 0,1682938 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,15447378 0,171987 ! regulation of tube size GO:0035150 71 42 0,000 0,15447378 0,17190745 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,15447378 0,17182798 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,15447378 0,17174857 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,15447378 0,17166924 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,15447378 0,17158999 ! regulation of protein secretion GO:0050708 71 42 0,000 0,15447378 0,1715108 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,15784745 0,17517572 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,15784745 0,17509496 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,15784745 0,17501427 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,15784745 0,17493365 ! neural tube development GO:0021915 77 43 0,000 0,15784745 0,17485311 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,15784745 0,17477265 ! striated muscle contraction GO:0006941 77 43 0,000 0,15784745 0,17469226 ! phagocytosis GO:0006909 90 43 0,000 0,15784745 0,17461194 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15784745 0,17453169 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,16120777 0,17816532 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,16120777 0,17808352 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,16120777 0,17800179 ! leukocyte migration GO:0050900 68 45 0,000 0,1645548 0,18161415 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,1645548 0,18153088 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,1645548 0,18144768 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,1645548 0,18136456 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,1645548 0,18128152 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,1645548 0,18119855 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,1645548 0,18111566 ! cell growth GO:0016049 84 45 0,000 0,1645548 0,18103285 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,16788858 0,18461605 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,16788858 0,18453171 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,16788858 0,18444745 ! positive regulation of defense response GO:0031349 76 47 0,000 0,17120916 0,1880097 ! response to calcium ion GO:0051592 81 47 0,000 0,17120916 0,18792393 ! endosome transport GO:0016197 108 47 0,000 0,17120916 0,18783823 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,17120916 0,18775262 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,17120916 0,18766708 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,17120916 0,18758162 ! JNK cascade GO:0007254 91 47 0,000 0,17120916 0,18749624 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,17120916 0,18741094 ! protein homooligomerization GO:0051260 76 47 0,000 0,17120916 0,18732571 ! Notch signaling pathway GO:0007219 96 48 0,000 0,17451661 0,19085771 ! cellular component disassembly GO:0022411 86 48 0,000 0,17451661 0,19077099 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,17451661 0,19068436 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,17451661 0,1905978 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,17451661 0,19051132 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,17451661 0,19042493 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,17451661 0,1903386 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,17781097 0,19384376 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,17781097 0,19375597 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,17781097 0,19366826 ! regulation of ion transport GO:0043269 77 49 0,000 0,17781097 0,19358063 ! peptide metabolic process GO:0006518 76 49 0,000 0,17781097 0,19349307 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,17781097 0,1934056 ! endocrine system development GO:0035270 104 49 0,000 0,17781097 0,1933182 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,17781097 0,19323089 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,17781097 0,19314365 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,17781097 0,19305649 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,18109228 0,19653046 ! regulation of ossification GO:0030278 117 50 0,000 0,18109228 0,19644185 ! inner ear development GO:0048839 79 50 0,000 0,18109228 0,19635333 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,18109228 0,19626488 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,18109228 0,19617651 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,18436062 0,1996272 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,18436062 0,1995374 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,18436062 0,19944768 ! excretion GO:0007588 83 51 0,000 0,18436062 0,19935804 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,18436062 0,19926848 ! chromatin remodeling GO:0006338 109 51 0,000 0,18436062 0,199179 ! vesicle organization GO:0016050 107 51 0,000 0,18436062 0,1990896 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,18436062 0,19900029 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,18761601 0,20242337 ! membrane fusion GO:0006944 110 52 0,000 0,18761601 0,20233264 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,18761601 0,20224199 ! amino acid activation GO:0043038 92 52 0,000 0,18761601 0,20215142 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,18761601 0,20206093 ! synapse organization GO:0050808 85 52 0,000 0,18761601 0,20197052 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,19085852 0,20536923 ! RNA catabolic process GO:0006401 93 53 0,000 0,19085852 0,20527743 ! regulation of translational initiation GO:0006446 82 53 0,000 0,19085852 0,2051857 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,19085852 0,20509406 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,19085852 0,2050025 ! cell maturation GO:0048469 100 53 0,000 0,19085852 0,20491102 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,1940882 0,20828555 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,1940882 0,20819269 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,1940882 0,20809991 ! cell recognition GO:0008037 85 54 0,000 0,1940882 0,20800722 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,1940882 0,2079146 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,1940882 0,20782207 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,1940882 0,20772963 ! chloride transport GO:0006821 90 55 0,000 0,19730509 0,21107872 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,19730509 0,21098491 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,19730509 0,21089118 ! gastrulation GO:0007369 112 55 0,000 0,19730509 0,21079753 ! RNA elongation GO:0006354 79 55 0,000 0,19730509 0,21070397 ! nuclear export GO:0051168 97 55 0,000 0,19730509 0,21061049 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,19730509 0,21051709 ! sensory perception of smell GO:0007608 80 56 0,000 0,20050925 0,21384098 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,20050925 0,21374623 ! proton transport GO:0015992 94 56 0,000 0,20050925 0,21365157 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,20370072 0,21695615 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,20370072 0,21686015 ! hydrogen transport GO:0006818 97 58 0,000 0,20687956 0,22014694 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,20687956 0,22004961 ! regulation of endocytosis GO:0030100 91 58 0,000 0,20687956 0,21995237 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,20687956 0,21985522 ! positive regulation of secretion GO:0051047 95 59 0,000 0,21004581 0,22312151 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,21004581 0,22302305 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,21004581 0,22292467 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,21004581 0,22282638 ! DNA catabolic process GO:0006308 86 59 0,000 0,21004581 0,22272818 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,21004581 0,22263006 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,21319953 0,22587322 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,21319953 0,2257738 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,21634077 0,22899951 ! mesoderm development GO:0007498 119 61 0,000 0,21634077 0,22889881 ! tRNA processing GO:0008033 89 61 0,000 0,21634077 0,22879819 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,21634077 0,22869767 ! ear development GO:0043583 103 62 0,000 0,21946956 0,23190328 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,21946956 0,23180148 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,22258597 0,23498984 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,22258597 0,23488678 ! detection of external stimulus GO:0009581 91 63 0,000 0,22258597 0,2347838 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,22258597 0,23468092 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,22569004 0,23784943 ! cell redox homeostasis GO:0045454 102 64 0,000 0,22569004 0,23774529 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,22569004 0,23764124 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,22569004 0,23753729 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,22569004 0,23743342 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,22878182 0,24058088 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,22878182 0,24047578 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,22878182 0,24037077 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,22878182 0,24026585 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,23186135 0,24339372 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,23186135 0,24328758 ! extracellular matrix organization GO:0030198 133 66 0,000 0,23186135 0,24318152 ! secondary metabolic process GO:0019748 116 66 0,000 0,23186135 0,24307556 ! cell projection assembly GO:0030031 120 66 0,000 0,23186135 0,24296969 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,23492869 0,24607681 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,23492869 0,24596973 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,23492869 0,24586274 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,23492869 0,24575584 ! adaptive immune response GO:0002250 119 67 0,000 0,23492869 0,24564904 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,23492869 0,24554233 ! amino acid transport GO:0006865 125 68 0,000 0,23798389 0,24862754 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,23798389 0,24851963 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,23798389 0,24841181 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,23798389 0,24830409 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,23798389 0,24819646 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,23798389 0,24808892 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,24102698 0,25115241 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,24102698 0,25104369 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,24102698 0,25093506 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,24102698 0,25082652 ! antigen processing and presentation GO:0019882 104 69 0,000 0,24102698 0,25071808 ! appendage morphogenesis GO:0035107 135 70 0,000 0,24405802 0,25376128 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,24707706 0,25678938 ! appendage development GO:0048736 136 71 0,000 0,24707706 0,2566785 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,24707706 0,25656772 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,24707706 0,25645704 ! regulation of immune effector process GO:0002697 137 71 0,000 0,24707706 0,25634645 ! acute inflammatory response GO:0002526 113 72 0,000 0,25008414 0,2593545 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,25008414 0,25924276 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,25008414 0,25913111 ! regulation of blood pressure GO:0008217 125 73 0,000 0,25307931 0,26212175 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,25307931 0,26200896 ! axon guidance GO:0007411 139 73 0,000 0,25307931 0,26189627 ! fertilization GO:0009566 90 73 0,000 0,25307931 0,26178367 ! transition metal ion transport GO:0000041 126 74 0,000 0,25606262 0,26475576 ! neurotransmitter transport GO:0006836 123 74 0,000 0,25606262 0,26464204 ! exocytosis GO:0006887 133 74 0,000 0,25606262 0,26452841 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,25606262 0,26441488 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,25903411 0,26736854 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,25903411 0,26725389 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,25903411 0,26713934 ! rhythmic process GO:0048511 128 75 0,000 0,25903411 0,26702488 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,26199383 0,26996024 ! defense response to bacterium GO:0042742 89 76 0,000 0,26199383 0,26984467 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,26199383 0,26972921 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,26494183 0,27264758 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,26494183 0,27253101 ! blood coagulation GO:0007596 146 78 0,000 0,26787814 0,27543368 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,26787814 0,27531603 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,26787814 0,27519847 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,27080283 0,27808434 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,27080283 0,2779657 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,27080283 0,27784717 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,27080283 0,27772873 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,27371593 0,28059673 ! response to metal ion GO:0010038 140 80 0,000 0,27371593 0,28047722 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,27371593 0,28035782 ! inorganic anion transport GO:0015698 138 80 0,000 0,27371593 0,28023852 ! digestion GO:0007586 112 81 0,000 0,27661749 0,28308876 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,27661749 0,2829684 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,27661749 0,28284814 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,27950755 0,28568189 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,27950755 0,28556058 ! response to nutrient GO:0007584 125 82 0,000 0,27950755 0,28543937 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,27950755 0,28531827 ! regulation of lyase activity GO:0051339 160 83 0,000 0,28238616 0,28813448 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,28525337 0,29093667 ! hemostasis GO:0007599 158 84 0,000 0,28525337 0,29081339 ! negative regulation of transport GO:0051051 153 84 0,000 0,28525337 0,29069021 ! regulation of ligase activity GO:0051340 142 84 0,000 0,28525337 0,29056715 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,28525337 0,29044418 ! response to unfolded protein GO:0006986 131 85 0,000 0,28810921 0,2932279 ! nucleosome assembly GO:0006334 122 85 0,000 0,28810921 0,29310392 ! amine biosynthetic process GO:0009309 138 86 0,000 0,29095374 0,29587265 ! response to inorganic substance GO:0010035 153 86 0,000 0,29095374 0,29574765 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,29095374 0,29562276 ! chromatin assembly GO:0031497 124 86 0,000 0,29095374 0,29549797 ! tube morphogenesis GO:0035239 176 86 0,000 0,29095374 0,29537329 ! amine transport GO:0015837 155 86 0,000 0,29095374 0,29524871 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,293787 0,29799811 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,293787 0,29787253 ! cellular respiration GO:0045333 135 88 0,000 0,29660903 0,30060713 ! gland development GO:0048732 206 88 0,000 0,29660903 0,30048056 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,29660903 0,30035409 ! cellular defense response GO:0006968 114 89 0,000 0,29941987 0,30307287 ! ossification GO:0001503 188 90 0,000 0,30221958 0,3057781 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,30221958 0,30564956 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,30221958 0,30552114 ! bone development GO:0060348 189 91 0,000 0,30500819 0,30821071 ! sterol metabolic process GO:0016125 152 91 0,000 0,30500819 0,30808132 ! response to protein stimulus GO:0051789 149 91 0,000 0,30500819 0,30795204 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,30500819 0,30782287 ! nucleosome organization GO:0034728 138 92 0,000 0,30778575 0,31049582 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,30778575 0,31036568 ! vitamin metabolic process GO:0006766 139 92 0,000 0,30778575 0,31023566 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,3105523 0,31289315 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,3105523 0,31276218 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,3105523 0,31263132 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,31330789 0,31527344 ! female pregnancy GO:0007565 164 94 0,000 0,31330789 0,31514163 ! transcription initiation GO:0006352 153 94 0,000 0,31330789 0,31500994 ! regulation of T cell activation GO:0050863 158 94 0,000 0,31330789 0,31487836 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,31605255 0,31750415 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,31878634 0,32011683 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,31878634 0,31998328 ! positive regulation of immune response GO:0050778 156 96 0,000 0,31878634 0,31984985 ! detection of stimulus GO:0051606 151 96 0,000 0,31878634 0,31971652 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,32150929 0,32231306 ! hormone metabolic process GO:0042445 157 97 0,000 0,32150929 0,32217882 ! response to virus GO:0009615 160 98 0,000 0,32422144 0,32476136 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,32422144 0,32462621 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,32422144 0,32449118 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,32692285 0,32705878 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,32692285 0,32692285