pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1218-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! neutrophil homeostasis GO:0001780 6 6 4,000 2,545E-11 5,854E-08 ! pericardium development GO:0060039 8 7 4,000 8,87E-11 1,02E-07 ! myeloid cell homeostasis GO:0002262 8 8 4,000 2,355E-10 1,806E-07 ! leukocyte homeostasis GO:0001776 33 22 5,000 1,526E-09 8,777E-07 ! post-embryonic development GO:0009791 42 26 5,000 4,628E-09 2,129E-06 ! embryonic hindlimb morphogenesis GO:0035116 25 15 4,000 1,226E-08 4,698E-06 ! embryonic forelimb morphogenesis GO:0035115 17 15 4,000 1,226E-08 4,027E-06 ! forelimb morphogenesis GO:0035136 19 17 4,000 2,504E-08 7,198E-06 ! hindlimb morphogenesis GO:0035137 32 20 4,000 6,193E-08 1,583E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 3,246E-07 7,465E-05 ! homeostasis of number of cells GO:0048872 84 61 5,000 9,58E-07 2,003E-04 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 2,000 1,542E-06 2,956E-04 ! response to hypoxia GO:0001666 132 72 5,000 2,569E-06 4,546E-04 ! response to oxygen levels GO:0070482 137 74 5,000 3,02E-06 4,961E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 3,484E-06 5,342E-04 ! regulation of smooth muscle cell migration GO:0014910 19 7 2,000 5,356E-06 7,699E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 8,536E-06 1,155E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 3,000 1,116E-05 1,426E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 2,000 1,815E-05 2,197E-03 ! embryonic limb morphogenesis GO:0030326 86 60 4,000 1,838E-05 2,113E-03 GO:0035113|embryonic appendage morphogenesis, ! appendage morphogenesis GO:0035107 93 64 4,000 2,522E-05 2,762E-03 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 94 65 4,000 2,72E-05 2,844E-03 GO:0060173|limb development, ! auditory receptor cell differentiation GO:0042491 25 12 2,000 3,301E-05 3,301E-03 ! negative regulation of mitotic cell cycle GO:0045930 23 13 2,000 4,274E-05 4,096E-03 ! positive regulation of protein import into nucleus GO:0042307 23 13 2,000 4,274E-05 3,932E-03 ! regulation of survival gene product expression GO:0045884 20 15 2,000 6,746E-05 5,968E-03 ! defense response to virus GO:0051607 27 15 2,000 6,746E-05 5,747E-03 ! forebrain development GO:0030900 131 80 4,000 7,425E-05 6,099E-03 ! inner ear receptor cell differentiation GO:0060113 30 16 2,000 8,27E-05 6,559E-03 ! regulation of protein localization GO:0032880 132 85 4,000 9,917E-05 7,603E-03 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 2,000 1E-04 7,422E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 1E-04 7,19E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 1,048E-04 7,307E-03 ! response to UV GO:0009411 75 46 3,000 1,121E-04 7,584E-03 ! interphase GO:0051325 159 88 4,000 1,169E-04 7,684E-03 ! mechanoreceptor differentiation GO:0042490 32 18 2,000 1,196E-04 7,639E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 1,414E-04 8,791E-03 ! ear development GO:0043583 72 50 3,000 1,556E-04 9,419E-03 ! regulation of binding GO:0051098 151 95 4,000 1,679E-04 9,899E-03 ! regulation of protein catabolic process GO:0042176 77 51 3,000 1,682E-04 9,669E-03 ! in utero embryonic development GO:0001701 147 96 4,000 1,763E-04 9,891E-03 ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 2,544E-04 0,01393312 ! response to peptide hormone stimulus GO:0043434 84 57 3,000 2,593E-04 0,01386838 ! SMAD protein complex assembly GO:0007183 9 5 1,000 2,891E-04 0,01511269 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,891E-04 0,01477685 ! endochondral ossification GO:0001958 12 5 1,000 2,891E-04 0,01445561 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 2,891E-04 0,01414805 ! valine metabolic process GO:0006573 8 5 1,000 2,891E-04 0,0138533 ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 2,891E-04 0,01357058 ! early endosome to late endosome transport GO:0045022 11 5 1,000 2,891E-04 0,01329916 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 2,891E-04 0,0130384 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 2,891E-04 0,01278766 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 2,891E-04 0,01254638 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 2,896E-04 0,01233632 ! mitochondrial membrane organization GO:0007006 39 24 2,000 2,896E-04 0,01211203 ! lung development GO:0030324 94 59 3,000 2,963E-04 0,0121683 ! urogenital system development GO:0001655 101 61 3,000 3,369E-04 0,01359447 ! negative regulation of cell growth GO:0030308 106 62 3,000 3,587E-04 0,01422243 ! respiratory tube development GO:0030323 99 62 3,000 3,587E-04 0,01398138 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 3,814E-04 0,01461977 ! negative regulation of cell size GO:0045792 108 64 3,000 4,051E-04 0,01527538 ! respiratory system development GO:0060541 100 64 3,000 4,051E-04 0,015029 ! prostate gland development GO:0030850 9 6 1,000 4,321E-04 0,01577625 ! male meiosis GO:0007140 7 6 1,000 4,321E-04 0,01552975 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 4,321E-04 0,01529083 ! pigment granule organization GO:0048753 11 6 1,000 4,321E-04 0,01505915 ! neuron apoptosis GO:0051402 8 6 1,000 4,321E-04 0,01483438 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 4,321E-04 0,01461623 ! positive regulation of multicellular organism growth GO:0040018 38 28 2,000 4,615E-04 0,0153825 ! regulation of protein import into nucleus GO:0042306 53 29 2,000 5,127E-04 0,01684591 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 5,703E-04 0,01847423 ! regulation of catabolic process GO:0009894 106 70 3,000 5,703E-04 0,01821765 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 6,028E-04 0,01899367 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 6,028E-04 0,018737 ! regulation of granule cell precursor proliferation GO:0021936 11 7 1,000 6,028E-04 0,01848717 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of pigmentation during development GO:0048070 15 7 1,000 6,028E-04 0,01824392 ! organ growth GO:0035265 11 7 1,000 6,028E-04 0,01800698 ! behavioral fear response GO:0001662 13 7 1,000 6,028E-04 0,01777613 GO:0002209|behavioral defense response, ! response to UV-B GO:0010224 11 7 1,000 6,028E-04 0,01755111 ! fibrinolysis GO:0042730 9 7 1,000 6,028E-04 0,01733172 ! B cell lineage commitment GO:0002326 17 7 1,000 6,028E-04 0,01711775 ! T cell lineage commitment GO:0002360 12 7 1,000 6,028E-04 0,016909 ! peptidyl-threonine modification GO:0018210 18 7 1,000 6,028E-04 0,01670527 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 6,028E-04 0,0165064 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 6,346E-04 0,01717195 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of protein stability GO:0031647 48 32 2,000 6,878E-04 0,01839436 ! cellular response to hormone stimulus GO:0032870 109 74 3,000 7,039E-04 0,01860949 ! negative regulation of growth GO:0045926 123 75 3,000 7,405E-04 0,01935434 ! regulation of proteolysis GO:0030162 50 33 2,000 7,536E-04 0,01947507 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 7,536E-04 0,01925868 ! regulation of protein transport GO:0051223 114 76 3,000 7,784E-04 0,01967457 GO:0070201|regulation of establishment of protein localization, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 8,009E-04 0,02002362 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 8,009E-04 0,01980831 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 8,009E-04 0,01959759 ! succinate metabolic process GO:0006105 14 8 1,000 8,009E-04 0,0193913 ! polyamine biosynthetic process GO:0006596 9 8 1,000 8,009E-04 0,0191893 ! melanin metabolic process GO:0006582 12 8 1,000 8,009E-04 0,01899147 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 8,009E-04 0,01879768 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 8,009E-04 0,01860781 ! regulation of DNA binding GO:0051101 119 77 3,000 8,177E-04 0,01880699 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 8,233E-04 0,01874816 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 8,969E-04 0,02022516 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 1,000 1,026E-03 0,02291386 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 1,000 1,026E-03 0,02269353 GO:0010469|regulation of receptor activity, ! T cell selection GO:0045058 18 9 1,000 1,026E-03 0,02247741 ! positive regulation of survival gene product expression GO:0045885 13 9 1,000 1,026E-03 0,02226535 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,026E-03 0,02205727 GO:0006600|creatine metabolic process, ! receptor clustering GO:0043113 15 9 1,000 1,026E-03 0,02185303 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 1,026E-03 0,02165255 ! oocyte differentiation GO:0009994 12 9 1,000 1,026E-03 0,02145571 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 1,000 1,026E-03 0,02126241 ! spleen development GO:0048536 15 9 1,000 1,026E-03 0,02107257 ! response to nicotine GO:0035094 16 9 1,000 1,026E-03 0,02088609 ! localization within membrane GO:0051668 15 9 1,000 1,026E-03 0,02070287 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 1,184E-03 0,02367345 ! cell cycle arrest GO:0007050 150 86 3,000 1,236E-03 0,02451281 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,278E-03 0,02512586 ! hair follicle morphogenesis GO:0031069 17 10 1,000 1,278E-03 0,02491292 ! blood vessel remodeling GO:0001974 21 10 1,000 1,278E-03 0,02470357 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,278E-03 0,02449771 ! polyamine metabolic process GO:0006595 14 10 1,000 1,278E-03 0,02429525 ! B cell proliferation GO:0042100 14 10 1,000 1,278E-03 0,02409611 ! fear response GO:0042596 16 10 1,000 1,278E-03 0,0239002 ! negative regulation of ossification GO:0030279 19 10 1,000 1,278E-03 0,02370746 ! alpha-beta T cell activation GO:0046631 16 10 1,000 1,278E-03 0,0235178 ! protein sumoylation GO:0016925 12 10 1,000 1,278E-03 0,02333115 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 1,278E-03 0,02314744 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 1,328E-03 0,02385645 ! inner ear development GO:0048839 57 40 2,000 1,328E-03 0,02367151 ! positive regulation of protein transport GO:0051222 55 40 2,000 1,328E-03 0,02348942 ! positive regulation of DNA binding GO:0043388 57 41 2,000 1,427E-03 0,02505192 ! mitochondrial transport GO:0006839 60 42 2,000 1,531E-03 0,02666981 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 1,531E-03 0,02646929 ! branching morphogenesis of a tube GO:0048754 72 42 2,000 1,531E-03 0,02627176 ! virus-host interaction GO:0019048 17 11 1,000 1,557E-03 0,0265207 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,557E-03 0,02632569 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 1,557E-03 0,02613354 ! focal adhesion formation GO:0048041 24 11 1,000 1,557E-03 0,02594416 ! chondrocyte differentiation GO:0002062 17 11 1,000 1,557E-03 0,02575751 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 1,557E-03 0,02557353 ! T cell homeostasis GO:0043029 20 11 1,000 1,557E-03 0,02539216 ! digestive tract morphogenesis GO:0048546 15 11 1,000 1,557E-03 0,02521334 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of binding GO:0051099 59 43 2,000 1,639E-03 0,0263611 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 1,639E-03 0,02617804 ! response to insulin stimulus GO:0032868 63 43 2,000 1,639E-03 0,0259975 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 1,651E-03 0,02601567 ! negative regulation of cell migration GO:0030336 92 44 2,000 1,752E-03 0,0274125 ! response to light stimulus GO:0009416 153 96 3,000 1,856E-03 0,02884068 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 1,861E-03 0,02873268 ! histone acetylation GO:0016573 23 12 1,000 1,861E-03 0,02854113 ! gland morphogenesis GO:0022612 23 12 1,000 1,861E-03 0,02835212 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,861E-03 0,02816559 ! response to gamma radiation GO:0010332 20 12 1,000 1,861E-03 0,0279815 ! positive regulation of cell cycle GO:0045787 77 45 2,000 1,87E-03 0,02792586 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,192E-03 0,03252704 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 2,192E-03 0,03231853 ! cellular pigmentation GO:0033059 24 13 1,000 2,192E-03 0,03211268 ! lymphocyte homeostasis GO:0002260 24 13 1,000 2,192E-03 0,03190944 ! regulation of intracellular transport GO:0032386 78 49 2,000 2,39E-03 0,03457226 ! morphogenesis of a branching structure GO:0001763 86 49 2,000 2,39E-03 0,03435618 ! positive regulation of growth GO:0045927 67 50 2,000 2,533E-03 0,03618021 ! regulation of multicellular organism growth GO:0040014 65 50 2,000 2,533E-03 0,03595688 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 2,548E-03 0,0359583 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,548E-03 0,03573904 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 2,548E-03 0,03552244 ! activation of MAPKK activity GO:0000186 21 14 1,000 2,548E-03 0,03530845 ! epidermis morphogenesis GO:0048730 29 14 1,000 2,548E-03 0,03509702 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 2,548E-03 0,03488811 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 27 14 1,000 2,548E-03 0,03468167 ! negative regulation of blood coagulation GO:0030195 19 14 1,000 2,548E-03 0,03447766 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,548E-03 0,03427604 ! positive regulation of cell migration GO:0030335 92 51 2,000 2,68E-03 0,03584247 ! negative regulation of cell motion GO:0051271 104 51 2,000 2,68E-03 0,03563529 ! metencephalon development GO:0022037 19 15 1,000 2,93E-03 0,0387302 ! lipid phosphorylation GO:0046834 23 15 1,000 2,93E-03 0,03850889 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 1,000 2,93E-03 0,03829009 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 2,93E-03 0,03807376 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 2,93E-03 0,03785986 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 2,93E-03 0,03764835 ! kidney development GO:0001822 90 53 2,000 2,992E-03 0,03822689 ! regulation of mitosis GO:0007088 84 54 2,000 3,155E-03 0,0400948 GO:0051783|regulation of nuclear division, ! protein amino acid acetylation GO:0006473 28 16 1,000 3,337E-03 0,04216815 ! regulation of protein binding GO:0043393 27 16 1,000 3,337E-03 0,04193772 ! oogenesis GO:0048477 23 16 1,000 3,337E-03 0,0417098 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 3,337E-03 0,04148434 ! negative regulation of translation GO:0017148 22 16 1,000 3,337E-03 0,04126131 ! positive regulation of cell motion GO:0051272 99 56 2,000 3,499E-03 0,04303294 ! signal complex assembly GO:0007172 29 17 1,000 3,768E-03 0,04610217 ! regulation of viral genome replication GO:0045069 24 17 1,000 3,768E-03 0,04585825 ! cell-substrate junction assembly GO:0007044 39 17 1,000 3,768E-03 0,04561689 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 3,768E-03 0,04537805 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 3,768E-03 0,04514171 ! peptidyl-serine modification GO:0018209 27 17 1,000 3,768E-03 0,04490782 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 3,768E-03 0,04467633 ! negative regulation of coagulation GO:0050819 23 17 1,000 3,768E-03 0,04444722 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 3,864E-03 0,045346 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 2,000 4,055E-03 0,04734743 ! activation of MAPK activity GO:0000187 84 59 2,000 4,055E-03 0,0471083 ! actin filament organization GO:0007015 95 59 2,000 4,055E-03 0,04687157 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 4,224E-03 0,04858117 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 4,224E-03 0,04833948 ! somitogenesis GO:0001756 24 18 1,000 4,224E-03 0,04810017 ! gut development GO:0048565 26 18 1,000 4,224E-03 0,04786323 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,705E-03 0,05304438 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 4,705E-03 0,05278563 ! regeneration GO:0031099 32 19 1,000 4,705E-03 0,05252939 ! response to alkaloid GO:0043279 32 19 1,000 4,705E-03 0,05227562 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 4,705E-03 0,0520243 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 4,705E-03 0,05177538 ! apoptotic nuclear changes GO:0030262 24 19 1,000 4,705E-03 0,05152883 ! renal system process GO:0003014 35 19 1,000 4,705E-03 0,05128462 ! sarcomere organization GO:0045214 23 19 1,000 4,705E-03 0,05104271 ! protein stabilization GO:0050821 26 19 1,000 4,705E-03 0,05080307 ! regulation of transcription factor activity GO:0051090 97 63 2,000 4,877E-03 0,05241729 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 4,877E-03 0,05217349 ! response to ethanol GO:0045471 37 20 1,000 5,209E-03 0,05546778 ! multicellular organismal response to stress GO:0033555 32 20 1,000 5,209E-03 0,05521217 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 5,209E-03 0,0549589 ! positive regulation of B cell activation GO:0050871 31 20 1,000 5,209E-03 0,05470795 ! reproductive structure development GO:0048608 90 65 2,000 5,323E-03 0,05564795 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 5,737E-03 0,0597085 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 5,737E-03 0,05943954 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 5,737E-03 0,05917299 ! protein amino acid acylation GO:0043543 37 21 1,000 5,737E-03 0,05890883 ! ovarian follicle development GO:0001541 30 21 1,000 5,737E-03 0,05864701 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 5,737E-03 0,05838751 ! cell aging GO:0007569 32 21 1,000 5,737E-03 0,0581303 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 5,737E-03 0,05787534 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,737E-03 0,05762261 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 5,737E-03 0,05737208 ! response to cytokine stimulus GO:0034097 47 21 1,000 5,737E-03 0,05712371 ! activation of protein kinase activity GO:0032147 102 69 2,000 6,286E-03 0,06231764 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 6,289E-03 0,06207746 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 6,289E-03 0,06181217 ! molting cycle process GO:0022404 40 22 1,000 6,289E-03 0,06154914 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 6,289E-03 0,06128834 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 6,289E-03 0,06102974 GO:0010810|regulation of cell-substrate adhesion, ! ureteric bud development GO:0001657 32 22 1,000 6,289E-03 0,06077331 ! regulation of blood coagulation GO:0030193 34 22 1,000 6,289E-03 0,06051903 ! response to metal ion GO:0010038 103 70 2,000 6,542E-03 0,062693 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 6,863E-03 0,06550143 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 6,863E-03 0,06523076 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 6,863E-03 0,06496232 ! osteoblast differentiation GO:0001649 40 23 1,000 6,863E-03 0,06469608 ! regulation of viral reproduction GO:0050792 32 23 1,000 6,863E-03 0,06443202 ! interaction with host GO:0051701 37 23 1,000 6,863E-03 0,0641701 ! lymphocyte proliferation GO:0046651 36 23 1,000 6,863E-03 0,0639103 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 6,863E-03 0,0636526 ! negative regulation of catabolic process GO:0009895 34 23 1,000 6,863E-03 0,06339696 ! negative regulation of transport GO:0051051 116 73 2,000 7,347E-03 0,06758879 ! tube morphogenesis GO:0035239 118 73 2,000 7,347E-03 0,06731951 ! mitochondrion organization GO:0007005 104 73 2,000 7,347E-03 0,06705237 ! receptor metabolic process GO:0043112 37 24 1,000 7,461E-03 0,06782751 ! response to toxin GO:0009636 38 24 1,000 7,461E-03 0,06756047 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 7,461E-03 0,06729553 ! response to inorganic substance GO:0010035 115 75 2,000 7,914E-03 0,07110444 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 8,081E-03 0,07232295 GO:0045936|negative regulation of phosphate metabolic process, ! male gonad development GO:0008584 33 25 1,000 8,081E-03 0,07204263 ! positive regulation of nuclear division GO:0051785 39 25 1,000 8,081E-03 0,07176447 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 8,081E-03 0,07148846 ! leukocyte proliferation GO:0070661 39 25 1,000 8,081E-03 0,07121455 GO:0032943|mononuclear cell proliferation, ! gland development GO:0048732 148 77 2,000 8,507E-03 0,0746804 ! sex differentiation GO:0007548 105 77 2,000 8,507E-03 0,07439644 ! regulation of coagulation GO:0050818 39 26 1,000 8,724E-03 0,0760044 ! myofibril assembly GO:0030239 36 27 1,000 9,389E-03 0,08148778 GO:0055002|striated muscle cell development, ! response to ionizing radiation GO:0010212 47 27 1,000 9,389E-03 0,08118144 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 9,389E-03 0,08087739 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 9,389E-03 0,08057561 ! negative regulation of protein transport GO:0051224 49 27 1,000 9,389E-03 0,08027607 ! regulation of cell cycle process GO:0010564 122 81 2,000 9,769E-03 0,08322018 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01007553 0,08551186 ! cell junction assembly GO:0034329 56 28 1,000 0,01007553 0,08519748 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01007553 0,0848854 ! regulation of B cell activation GO:0050864 42 28 1,000 0,01007553 0,0845756 ! ossification GO:0001503 134 82 2,000 0,010101 0,08448109 GO:0060348|bone development, ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,01078389 0,08986571 ! ovulation cycle process GO:0022602 41 29 1,000 0,01078389 0,08954129 ! muscle cell development GO:0055001 38 29 1,000 0,01078389 0,0892192 ! tissue homeostasis GO:0001894 42 29 1,000 0,01078389 0,08889941 GO:0048871|multicellular organismal homeostasis, ! Golgi vesicle transport GO:0048193 138 85 2,000 0,01113508 0,09146674 ! regulation of membrane potential GO:0042391 128 85 2,000 0,01113508 0,09114123 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 0,01113508 0,09081804 ! ovulation cycle GO:0042698 43 30 1,000 0,01151363 0,09357369 ! hindbrain development GO:0030902 45 30 1,000 0,01151363 0,0932442 ! response to heat GO:0009408 41 30 1,000 0,01151363 0,09291703 ! negative regulation of secretion GO:0051048 49 31 1,000 0,01226452 0,09863075 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 0,01226452 0,09828709 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,01226452 0,09794582 ! segmentation GO:0035282 41 31 1,000 0,01226452 0,0976069 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,01226452 0,09727033 ! metanephros development GO:0001656 58 31 1,000 0,01226452 0,09693607 ! biogenic amine biosynthetic process GO:0042401 44 31 1,000 0,01226452 0,09660409 ! reproductive developmental process GO:0003006 127 89 2,000 0,0126058 0,09895335 ! protein modification by small protein conjugation GO:0032446 140 90 2,000 0,01299002 0,10162262 ! regulation of muscle development GO:0048634 48 32 1,000 0,0130363 0,10163896 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,0130363 0,10129559 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,0130363 0,10095452 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,0130363 0,10061575 ! response to virus GO:0009615 122 91 2,000 0,0133809 0,10293002 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 0,01382873 0,10602029 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! actomyosin structure organization GO:0031032 43 33 1,000 0,01382873 0,10566807 ! cell junction organization GO:0034330 63 33 1,000 0,01382873 0,10531817 ! nucleus organization GO:0006997 49 33 1,000 0,01382873 0,10497059 ! female gonad development GO:0008585 49 33 1,000 0,01382873 0,10462529 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,01382873 0,10428226 ! positive regulation of cell development GO:0010720 54 33 1,000 0,01382873 0,10394146 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,01464157 0,10969258 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,01464157 0,10933643 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,01464157 0,10898259 ! female gamete generation GO:0007292 43 34 1,000 0,01464157 0,10863103 ! protein modification by small protein conjugation or removal GO:0070647 148 96 2,000 0,01543563 0,11415419 ! maintenance of protein location GO:0045185 65 35 1,000 0,01547458 0,11407545 ! pigment metabolic process GO:0042440 61 35 1,000 0,01547458 0,11371099 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01547458 0,11334885 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01632752 0,11921681 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 1,000 0,01632752 0,11883954 ! cellular amide metabolic process GO:0043603 52 36 1,000 0,01632752 0,11846465 ! negative regulation of binding GO:0051100 58 36 1,000 0,01632752 0,11809212 ! tissue remodeling GO:0048771 62 36 1,000 0,01632752 0,11772193 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,01632752 0,11735405 GO:0046660|female sex differentiation, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,01720015 0,12324095 ! regulation of protein secretion GO:0050708 51 37 1,000 0,01720015 0,12285821 ! Ras protein signal transduction GO:0007265 162 100 2,000 0,01720057 0,12248082 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,01809224 0,12843256 ! mesenchymal cell development GO:0014031 64 38 1,000 0,01809224 0,12803738 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 1,000 0,01809224 0,12764463 ! maintenance of location in cell GO:0051651 69 38 1,000 0,01809224 0,12725428 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,01900355 0,13325663 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,01900355 0,13285159 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,01900355 0,13244901 ! male sex differentiation GO:0046661 53 39 1,000 0,01900355 0,13204886 ! chromatin remodeling GO:0006338 68 39 1,000 0,01900355 0,13165112 ! developmental growth GO:0048589 62 39 1,000 0,01900355 0,13125577 ! cell growth GO:0016049 61 39 1,000 0,01900355 0,13086279 ! response to calcium ion GO:0051592 58 40 1,000 0,01993386 0,13685936 ! T cell differentiation GO:0030217 65 40 1,000 0,01993386 0,13645204 ! B cell differentiation GO:0030183 62 40 1,000 0,01993386 0,13604714 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,01993386 0,13564463 ! endosome transport GO:0016197 71 41 1,000 0,02088294 0,14168366 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,02185056 0,14781259 ! cellular component disassembly GO:0022411 64 42 1,000 0,02185056 0,14737912 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,02185056 0,14694819 ! activation of caspase activity GO:0006919 65 43 1,000 0,02283649 0,15313096 ! vesicle organization GO:0016050 79 43 1,000 0,02283649 0,15268582 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,02283649 0,15224325 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,02384051 0,15847738 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,0248624 0,16479402 ! regulation of ossification GO:0030278 71 46 1,000 0,02590195 0,17119102 ! histone modification GO:0016570 68 46 1,000 0,02590195 0,1707005 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02688015 0,17664096 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02688015 0,17613771 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02688015 0,17563731 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02688015 0,17513976 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02688015 0,17464501 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02688015 0,17415306 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02688015 0,17366386 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02688015 0,17317741 ! sleep GO:0030431 11 5 0,000 0,02688015 0,17269367 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02688015 0,17221263 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02688015 0,17173426 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02688015 0,17125854 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02688015 0,17078545 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02688015 0,17031497 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02688015 0,16984707 ! tongue development GO:0043586 6 5 0,000 0,02688015 0,16938174 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02688015 0,16891895 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02688015 0,16845868 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02688015 0,16800091 ! cobalt ion transport GO:0006824 9 5 0,000 0,02688015 0,16754562 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02688015 0,1670928 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02688015 0,16664241 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02688015 0,16619445 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02688015 0,16574889 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02688015 0,16530571 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02688015 0,16486489 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02688015 0,16442642 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02688015 0,16399028 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02688015 0,16355644 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02688015 0,16312489 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02688015 0,16269562 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02688015 0,16226859 ! malate metabolic process GO:0006108 7 5 0,000 0,02688015 0,16184381 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02688015 0,16142124 ! behavioral response to pain GO:0048266 7 5 0,000 0,02688015 0,16100087 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02688015 0,16058269 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02688015 0,16016667 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02688015 0,1597528 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02688015 0,15934107 ! mating behavior GO:0007617 6 5 0,000 0,02688015 0,15893145 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02688015 0,15852394 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02688015 0,1581185 ! rhythmic behavior GO:0007622 12 5 0,000 0,02688015 0,15771514 ! copulation GO:0007620 7 5 0,000 0,02688015 0,15731383 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02688015 0,15691455 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02688015 0,1565173 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02688015 0,15612206 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02688015 0,1557288 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02688015 0,15533752 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02688015 0,15494821 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02688015 0,15456084 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02688015 0,1541754 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02688015 0,15379188 ! response to protozoan GO:0001562 9 5 0,000 0,02688015 0,15341026 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02688015 0,15303053 ! lymph vessel development GO:0001945 7 5 0,000 0,02688015 0,15265268 ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02688015 0,15227669 ! parathyroid gland development GO:0060017 8 5 0,000 0,02688015 0,15190254 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02688015 0,15153023 ! anagen GO:0042640 6 5 0,000 0,02688015 0,15115974 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02688015 0,15079106 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02688015 0,15042417 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02688015 0,15005906 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02688015 0,14969573 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02688015 0,14933414 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02688015 0,1489743 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02688015 0,14861619 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02688015 0,1482598 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02688015 0,14790511 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02688015 0,14755211 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02688015 0,1472008 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02688015 0,14685115 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02688015 0,14650316 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02688015 0,14615682 ! ovulation GO:0030728 6 5 0,000 0,02688015 0,14581211 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02688015 0,14546902 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02688015 0,14512755 GO:0030033|microvillus assembly, ! response to pH GO:0009268 9 5 0,000 0,02688015 0,14478767 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02688015 0,14444938 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02688015 0,14411267 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02688015 0,14377752 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02688015 0,14344393 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02688015 0,14311189 ! polyol catabolic process GO:0046174 7 5 0,000 0,02688015 0,14278137 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02688015 0,14245238 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02688015 0,14212491 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02688015 0,14179893 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02688015 0,14147445 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02688015 0,14115145 ! urea metabolic process GO:0019627 6 5 0,000 0,02688015 0,14082992 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02688015 0,14050985 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02688015 0,14019124 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02688015 0,13987406 ! neutrophil activation GO:0042119 5 5 0,000 0,02688015 0,13955832 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02688015 0,139244 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02688015 0,13893109 ! response to food GO:0032094 5 5 0,000 0,02688015 0,13861958 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02688015 0,13830947 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02688015 0,13800075 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02688015 0,1376934 ! forebrain neuron development GO:0021884 7 5 0,000 0,02688015 0,13738741 ! melanosome organization GO:0032438 7 5 0,000 0,02688015 0,13708278 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02688015 0,1367795 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02688015 0,13647756 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02688015 0,13617695 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02688015 0,13587766 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02688015 0,13557968 ! nucleoside transport GO:0015858 6 5 0,000 0,02688015 0,13528301 ! nucleoside salvage GO:0043174 7 5 0,000 0,02688015 0,13498763 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02688015 0,13469354 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02688015 0,13440073 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02688015 0,13410919 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02688015 0,13381891 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02688015 0,13352988 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02688015 0,1332421 ! depyrimidination GO:0045008 8 5 0,000 0,02688015 0,13295556 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02688015 0,13267025 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02688015 0,13238616 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02688015 0,13210328 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02688015 0,13182161 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02688015 0,13154114 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02688015 0,13126186 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02688015 0,13098376 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02688015 0,13070684 ! monocyte differentiation GO:0030224 8 5 0,000 0,02688015 0,13043109 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02688015 0,13015649 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02688015 0,12988306 ! centrosome duplication GO:0051298 5 5 0,000 0,02688015 0,12961076 ! response to UV-C GO:0010225 6 5 0,000 0,02688015 0,12933961 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02688015 0,12906959 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02688015 0,1288007 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02688015 0,12853292 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02688015 0,12826625 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02688015 0,12800069 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02688015 0,12773623 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02688015 0,12747285 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02688015 0,12721057 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02688015 0,12694935 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02688015 0,12668921 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02688015 0,12643013 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02688015 0,12617211 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02688015 0,12591514 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02688015 0,12565922 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02688015 0,12540433 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02688015 0,12515048 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02688015 0,12489765 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02688015 0,12464584 ! neural tube patterning GO:0021532 6 5 0,000 0,02688015 0,12439504 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02688015 0,12414525 ! histone demethylation GO:0016577 9 5 0,000 0,02688015 0,12389646 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02688015 0,12364867 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02688015 0,12340187 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02688015 0,12315605 ! enteric nervous system development GO:0048484 8 5 0,000 0,02688015 0,1229112 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02688015 0,12266733 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02688015 0,12242443 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02688015 0,12218248 ! transcription termination GO:0006353 8 5 0,000 0,02688015 0,12194149 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02688015 0,12170145 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02688015 0,12146235 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02688015 0,12122419 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02688015 0,12098696 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02688015 0,12075065 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02688015 0,12051527 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02688015 0,12028081 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02688015 0,12004725 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02688015 0,1198146 ! apical protein localization GO:0045176 6 5 0,000 0,02688015 0,11958285 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02688015 0,119352 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02688015 0,11912203 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02688015 0,11889295 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02688015 0,11866475 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02688015 0,11843742 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02688015 0,11821096 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02688015 0,11798537 ! glial cell migration GO:0008347 10 5 0,000 0,02688015 0,11776064 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02688015 0,11753676 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02688015 0,11731373 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02688015 0,11709154 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02688015 0,1168702 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02688015 0,11664969 ! neural plate development GO:0001840 6 5 0,000 0,02688015 0,11643001 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02688015 0,11621116 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02688015 0,11599312 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02688015 0,11577591 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02688015 0,1155595 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02688015 0,11534391 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02688015 0,11512911 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02688015 0,11491512 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02688015 0,11470192 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02688015 0,11448951 ! spindle assembly GO:0051225 5 5 0,000 0,02688015 0,11427788 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02688015 0,11406704 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02688015 0,11385697 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02688015 0,11364767 ! organ regeneration GO:0031100 7 5 0,000 0,02688015 0,11343915 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02688015 0,11323138 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02688015 0,11302438 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02688015 0,11281813 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02688015 0,11261263 GO:0055081|anion homeostasis, ! response to estrogen stimulus GO:0043627 74 47 1,000 0,02695892 0,11273731 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02695892 0,11253271 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,02695892 0,11232884 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,02695892 0,11212572 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,02803312 0,11638297 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 1,000 0,02803312 0,11617327 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,02803312 0,11596433 ! germ cell development GO:0007281 68 49 1,000 0,02912431 0,12026197 ! cartilage development GO:0051216 70 49 1,000 0,02912431 0,12004645 ! maintenance of location GO:0051235 84 49 1,000 0,02912431 0,1198317 ! lipid modification GO:0030258 73 50 1,000 0,0302323 0,12416837 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 1,000 0,0302323 0,12394704 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,03135687 0,12832882 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,03135687 0,12810088 ! tRNA transcription GO:0009304 11 6 0,000 0,03216975 0,13118869 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03216975 0,1309565 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03216975 0,13072513 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03216975 0,13049457 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03216975 0,13026483 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03216975 0,13003589 ! regulation of helicase activity GO:0051095 11 6 0,000 0,03216975 0,12980776 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03216975 0,12958042 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03216975 0,12935388 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03216975 0,12912813 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03216975 0,12890317 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03216975 0,12867899 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03216975 0,12845559 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03216975 0,12823297 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03216975 0,12801111 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03216975 0,12779002 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03216975 0,12756969 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03216975 0,12735012 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03216975 0,12713131 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03216975 0,12691324 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,03216975 0,12669593 ! neuron adhesion GO:0007158 9 6 0,000 0,03216975 0,12647935 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03216975 0,12626352 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03216975 0,12604842 ! signal peptide processing GO:0006465 8 6 0,000 0,03216975 0,12583405 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03216975 0,12562041 ! mRNA stabilization GO:0048255 15 6 0,000 0,03216975 0,12540749 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03216975 0,1251953 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03216975 0,12498382 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03216975 0,12477305 ! opsonization GO:0008228 8 6 0,000 0,03216975 0,124563 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03216975 0,12435365 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03216975 0,124145 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03216975 0,12393705 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03216975 0,1237298 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03216975 0,12352324 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03216975 0,12331737 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03216975 0,12311218 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03216975 0,12290768 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03216975 0,12270385 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03216975 0,1225007 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03216975 0,12229822 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03216975 0,1220964 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03216975 0,12189526 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03216975 0,12169477 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03216975 0,12149494 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03216975 0,12129577 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03216975 0,12109725 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03216975 0,12089938 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03216975 0,12070215 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03216975 0,12050557 ! thymic T cell selection GO:0045061 12 6 0,000 0,03216975 0,12030963 ! protein lipoylation GO:0009249 10 6 0,000 0,03216975 0,12011432 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03216975 0,11991964 ! drug transport GO:0015893 6 6 0,000 0,03216975 0,1197256 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03216975 0,11953218 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,03216975 0,11933939 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03216975 0,11914722 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03216975 0,11895566 ! histidine metabolic process GO:0006547 6 6 0,000 0,03216975 0,11876472 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03216975 0,11857439 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03216975 0,11838467 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03216975 0,11819556 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03216975 0,11800705 ! adenohypophysis development GO:0021984 10 6 0,000 0,03216975 0,11781914 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03216975 0,11763183 ! hyperosmotic response GO:0006972 8 6 0,000 0,03216975 0,11744511 ! microtubule nucleation GO:0007020 10 6 0,000 0,03216975 0,11725899 ! ER overload response GO:0006983 7 6 0,000 0,03216975 0,11707345 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03216975 0,1168885 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03216975 0,11670413 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03216975 0,11652035 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03216975 0,11633714 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03216975 0,11615451 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03216975 0,11597245 ! response to dietary excess GO:0002021 7 6 0,000 0,03216975 0,11579096 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03216975 0,11561003 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03216975 0,11542967 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03216975 0,11524988 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03216975 0,11507064 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03216975 0,11489196 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03216975 0,11471383 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03216975 0,11453626 ! organic alcohol transport GO:0015850 9 6 0,000 0,03216975 0,11435923 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03216975 0,11418275 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03216975 0,11400681 ! male sex determination GO:0030238 9 6 0,000 0,03216975 0,11383142 ! carnitine transport GO:0015879 8 6 0,000 0,03216975 0,11365656 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03216975 0,11348224 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03216975 0,11330845 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03216975 0,1131352 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03216975 0,11296247 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03216975 0,11279028 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03216975 0,1126186 ! parturition GO:0007567 12 6 0,000 0,03216975 0,11244745 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03216975 0,11227681 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03216975 0,1121067 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03216975 0,1119371 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03216975 0,11176801 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03216975 0,11159943 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03216975 0,11143136 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03216975 0,11126379 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03216975 0,11109673 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03216975 0,11093017 ! macrophage differentiation GO:0030225 10 6 0,000 0,03216975 0,1107641 ! astrocyte development GO:0014002 14 6 0,000 0,03216975 0,11059854 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03216975 0,11043346 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03216975 0,11026888 ! interaction with symbiont GO:0051702 8 6 0,000 0,03216975 0,11010479 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03216975 0,10994119 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03216975 0,10977807 ! eating behavior GO:0042755 6 6 0,000 0,03216975 0,10961544 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03216975 0,10945329 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03216975 0,10929161 ! response to copper ion GO:0046688 9 6 0,000 0,03216975 0,10913041 ! DNA topological change GO:0006265 8 6 0,000 0,03216975 0,10896969 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03216975 0,10880944 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03216975 0,10864966 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03216975 0,10849035 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03216975 0,10833151 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03216975 0,10817313 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03216975 0,10801521 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03216975 0,10785776 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03216975 0,10770076 ! gas homeostasis GO:0033483 11 6 0,000 0,03216975 0,10754422 ! hair follicle maturation GO:0048820 7 6 0,000 0,03216975 0,10738813 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03216975 0,10723249 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03216975 0,10707731 ! Schwann cell development GO:0014044 14 6 0,000 0,03216975 0,10692257 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03216975 0,10676828 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03216975 0,10661444 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03216975 0,10646104 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03216975 0,10630808 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03216975 0,10615555 ! histone ubiquitination GO:0016574 7 6 0,000 0,03216975 0,10600347 ! regulation of meiosis GO:0040020 10 6 0,000 0,03216975 0,10585182 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03216975 0,1057006 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03216975 0,10554982 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03216975 0,10539946 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03216975 0,10524953 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03216975 0,10510003 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03216975 0,10495095 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03216975 0,1048023 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03216975 0,10465406 ! receptor internalization GO:0031623 9 6 0,000 0,03216975 0,10450624 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03216975 0,10435884 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03216975 0,10421186 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03216975 0,10406529 ! protein deubiquitination GO:0016579 8 6 0,000 0,03216975 0,10391913 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03216975 0,10377338 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,03216975 0,10362804 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03216975 0,10348311 ! axonal fasciculation GO:0007413 9 6 0,000 0,03216975 0,10333858 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03216975 0,10319445 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03216975 0,10305073 ! midbrain development GO:0030901 6 6 0,000 0,03216975 0,1029074 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03216975 0,10276447 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03216975 0,10262194 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03216975 0,10247981 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03216975 0,10233806 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03216975 0,10219671 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03216975 0,10205575 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03216975 0,10191518 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03216975 0,10177499 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03216975 0,10163519 ! adult feeding behavior GO:0008343 6 6 0,000 0,03216975 0,10149578 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03216975 0,10135674 ! blastocyst growth GO:0001832 15 6 0,000 0,03216975 0,10121809 ! pigment granule transport GO:0051904 12 6 0,000 0,03216975 0,10107981 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03216975 0,10094191 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03216975 0,10080439 ! catecholamine transport GO:0051937 7 6 0,000 0,03216975 0,10066724 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03216975 0,10053046 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03216975 0,10039406 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03216975 0,10025802 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03216975 0,10012236 ! protein prenylation GO:0018342 10 6 0,000 0,03216975 0,09998706 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03216975 0,09985212 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03216975 0,09971755 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03216975 0,09958334 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03216975 0,09944949 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03216975 0,099316 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,03249781 0,10019431 ! aging GO:0007568 79 52 1,000 0,03249781 0,10006018 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,03365491 0,10348435 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,03365491 0,10334618 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,03482797 0,10680578 ! DNA catabolic process GO:0006308 67 54 1,000 0,03482797 0,10666356 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,03482797 0,10652172 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,03482797 0,10638026 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0374309 0,11417914 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0374309 0,1140279 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0374309 0,11387707 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0374309 0,11372664 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0374309 0,11357661 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0374309 0,11342697 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0374309 0,11327772 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0374309 0,11312887 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0374309 0,1129804 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0374309 0,11283233 ! reproductive behavior GO:0019098 12 7 0,000 0,0374309 0,11268464 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0374309 0,11253734 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0374309 0,11239043 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0374309 0,1122439 ! oligopeptide transport GO:0006857 11 7 0,000 0,0374309 0,11209774 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0374309 0,11195197 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0374309 0,11180658 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0374309 0,11166157 ! RNA methylation GO:0001510 11 7 0,000 0,0374309 0,11151693 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0374309 0,11137266 ! fibril organization GO:0043206 13 7 0,000 0,0374309 0,11122877 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0374309 0,11108525 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0374309 0,1109421 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0374309 0,11079932 ! lipoprotein transport GO:0042953 9 7 0,000 0,0374309 0,1106569 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0374309 0,11051485 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0374309 0,11037316 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0374309 0,11023184 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0374309 0,11009088 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0374309 0,10995028 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0374309 0,10981004 ! chemosensory behavior GO:0007635 9 7 0,000 0,0374309 0,10967015 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0374309 0,10953062 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0374309 0,10939145 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0374309 0,10925262 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0374309 0,10911415 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0374309 0,10897604 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0374309 0,10883827 ! reflex GO:0060004 12 7 0,000 0,0374309 0,10870084 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0374309 0,10856377 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0374309 0,10842704 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0374309 0,10829065 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0374309 0,10815461 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0374309 0,10801891 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0374309 0,10788354 ! spinal cord patterning GO:0021511 7 7 0,000 0,0374309 0,10774852 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0374309 0,10761384 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0374309 0,10747949 ! adrenal gland development GO:0030325 17 7 0,000 0,0374309 0,10734547 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0374309 0,10721179 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0374309 0,10707844 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0374309 0,10694543 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0374309 0,10681274 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0374309 0,10668038 ! endosome organization GO:0007032 10 7 0,000 0,0374309 0,10654835 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0374309 0,10641665 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0374309 0,10628527 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0374309 0,10615421 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0374309 0,10602348 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0374309 0,10589307 ! galactose metabolic process GO:0006012 10 7 0,000 0,0374309 0,10576298 ! vesicle fusion GO:0006906 15 7 0,000 0,0374309 0,10563321 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0374309 0,10550376 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0374309 0,10537462 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0374309 0,1052458 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0374309 0,1051173 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0374309 0,10498911 ! retinol metabolic process GO:0042572 9 7 0,000 0,0374309 0,10486123 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0374309 0,10473366 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0374309 0,1046064 ! rRNA modification GO:0000154 12 7 0,000 0,0374309 0,10447945 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0374309 0,10435281 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0374309 0,10422647 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0374309 0,10410045 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0374309 0,10397472 ! intermediate filament organization GO:0045109 11 7 0,000 0,0374309 0,1038493 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0374309 0,10372418 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0374309 0,10359936 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0374309 0,10347484 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0374309 0,10335062 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0374309 0,1032267 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0374309 0,10310308 ! response to tropane GO:0014073 13 7 0,000 0,0374309 0,10297975 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0374309 0,10285671 ! melanosome localization GO:0032400 10 7 0,000 0,0374309 0,10273397 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0374309 0,10261152 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0374309 0,10248937 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0374309 0,1023675 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0374309 0,10224592 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0374309 0,10212464 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0374309 0,10200364 ! mast cell activation GO:0045576 9 7 0,000 0,0374309 0,10188292 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0374309 0,10176249 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0374309 0,10164235 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0374309 0,10152249 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0374309 0,10140291 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0374309 0,10128361 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0374309 0,10116459 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0374309 0,10104585 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0374309 0,1009274 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0374309 0,10080921 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0374309 0,10069131 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0374309 0,10057368 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0374309 0,10045632 ! response to tumor cell GO:0002347 12 7 0,000 0,0374309 0,10033924 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0374309 0,10022243 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0374309 0,10010589 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0374309 0,09998963 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0374309 0,09987363 ! diuresis GO:0030146 12 7 0,000 0,0374309 0,0997579 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0374309 0,09964244 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0374309 0,09952725 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0374309 0,09941232 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0374309 0,09929766 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0374309 0,09918326 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0374309 0,09906912 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0374309 0,09895525 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0374309 0,09884164 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0374309 0,09872829 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0374309 0,0986152 ! lymph node development GO:0048535 9 7 0,000 0,0374309 0,09850237 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0374309 0,09838979 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0374309 0,09827747 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0374309 0,09816541 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0374309 0,09805361 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0374309 0,09794206 ! ATP catabolic process GO:0006200 10 7 0,000 0,0374309 0,09783076 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0374309 0,09771971 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0374309 0,09760892 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0374309 0,09749838 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0374309 0,09738809 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0374309 0,09727804 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0374309 0,09716825 ! muscle adaptation GO:0043500 12 7 0,000 0,0374309 0,0970587 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0374309 0,0969494 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0374309 0,09684035 ! retina homeostasis GO:0001895 9 7 0,000 0,0374309 0,09673154 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0374309 0,09662297 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0374309 0,09651465 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0374309 0,09640657 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0374309 0,09629873 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0374309 0,09619114 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0374309 0,09608378 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0374309 0,09597666 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,03844089 0,09845661 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,03844089 0,09834709 GO:0048609|reproductive process in a multicellular organism, ! secondary metabolic process GO:0019748 84 57 1,000 0,03844089 0,09823782 ! gonad development GO:0008406 79 57 1,000 0,03844089 0,09812879 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,03967576 0,1011688 ! viral reproductive process GO:0022415 87 58 1,000 0,03967576 0,10105677 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,0421902 0,10734233 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,0421902 0,10722372 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,0421902 0,10710537 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04266375 0,10818812 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04266375 0,10806897 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,04266375 0,10795008 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04266375 0,10783146 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04266375 0,10771309 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04266375 0,10759498 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04266375 0,10747714 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04266375 0,10735955 ! phosphate transport GO:0006817 10 8 0,000 0,04266375 0,10724221 ! N-glycan processing GO:0006491 12 8 0,000 0,04266375 0,10712514 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04266375 0,10700831 ! UTP metabolic process GO:0046051 8 8 0,000 0,04266375 0,10689175 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04266375 0,10677543 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04266375 0,10665937 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,04266375 0,10654357 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04266375 0,10642801 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,04266375 0,1063127 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04266375 0,10619765 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04266375 0,10608284 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,04266375 0,10596828 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04266375 0,10585396 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,04266375 0,1057399 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04266375 0,10562608 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04266375 0,1055125 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04266375 0,10539917 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04266375 0,10528608 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04266375 0,10517323 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04266375 0,10506063 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04266375 0,10494826 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04266375 0,10483614 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04266375 0,10472425 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04266375 0,10461261 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04266375 0,1045012 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04266375 0,10439003 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04266375 0,10427909 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04266375 0,10416839 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04266375 0,10405793 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04266375 0,1039477 GO:0006559|L-phenylalanine catabolic process, ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04266375 0,1038377 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04266375 0,10372793 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,04266375 0,1036184 ! macrophage activation GO:0042116 12 8 0,000 0,04266375 0,1035091 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04266375 0,10340003 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04266375 0,10329118 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04266375 0,10318257 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04266375 0,10307419 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04266375 0,10296603 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04266375 0,1028581 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04266375 0,10275039 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04266375 0,10264291 ! ruffle organization GO:0031529 11 8 0,000 0,04266375 0,10253566 ! osteoblast development GO:0002076 13 8 0,000 0,04266375 0,10242863 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04266375 0,10232182 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04266375 0,10221523 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04266375 0,10210887 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04266375 0,10200273 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04266375 0,10189681 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04266375 0,1017911 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04266375 0,10168562 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04266375 0,10158036 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04266375 0,10147531 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,04266375 0,10137048 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,04266375 0,10126587 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04266375 0,10116147 ! segment specification GO:0007379 10 8 0,000 0,04266375 0,10105729 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04266375 0,10095332 ! cellular extravasation GO:0045123 11 8 0,000 0,04266375 0,10084956 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04266375 0,10074602 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04266375 0,10064269 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04266375 0,10053957 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,04266375 0,10043667 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04266375 0,10033397 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04266375 0,10023149 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04266375 0,10012921 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04266375 0,10002714 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04266375 0,09992528 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04266375 0,09982363 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04266375 0,09972218 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04266375 0,09962094 ! icosanoid secretion GO:0032309 12 8 0,000 0,04266375 0,0995199 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04266375 0,09941907 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04266375 0,09931845 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04266375 0,09921802 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04266375 0,0991178 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04266375 0,09901778 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04266375 0,09891797 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04266375 0,09881835 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04266375 0,09871894 ! sterol catabolic process GO:0016127 9 8 0,000 0,04266375 0,09861972 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04266375 0,09852071 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04266375 0,09842189 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04266375 0,09832327 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04266375 0,09822485 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04266375 0,09812662 ! prophase GO:0051324 11 8 0,000 0,04266375 0,0980286 ! S phase GO:0051320 8 8 0,000 0,04266375 0,09793076 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04266375 0,09783313 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04266375 0,09773568 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04266375 0,09763843 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04266375 0,09754138 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04266375 0,09744451 ! hormone catabolic process GO:0042447 13 8 0,000 0,04266375 0,09734784 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04266375 0,09725136 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04266375 0,09715507 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04266375 0,09705898 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04266375 0,09696307 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,04266375 0,09686735 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04266375 0,09677182 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04266375 0,09667648 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04266375 0,09658132 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04266375 0,09648636 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04266375 0,09639158 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04266375 0,09629698 ! regulation of embryonic development GO:0045995 16 8 0,000 0,04266375 0,09620257 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04266375 0,09610835 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04266375 0,09601431 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,04266375 0,09592045 ! meiosis GO:0007126 96 61 1,000 0,04346937 0,09763628 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,04346937 0,09754102 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,04346937 0,09744596 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,04346937 0,09735107 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,04476292 0,10015049 ! meiotic cell cycle GO:0051321 97 62 1,000 0,04476292 0,10005316 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,04607065 0,1028762 ! viral reproduction GO:0016032 92 63 1,000 0,04607065 0,10277642 ! regulation of lipase activity GO:0060191 109 63 1,000 0,04607065 0,10267683 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,04739238 0,1055203 ! regulation of developmental growth GO:0048638 13 9 0,000 0,04786845 0,10647721 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,04786845 0,10637433 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04786845 0,10627166 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04786845 0,10616918 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04786845 0,10606689 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04786845 0,10596481 ! CTP metabolic process GO:0046036 9 9 0,000 0,04786845 0,10586292 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04786845 0,10576123 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04786845 0,10565973 ! GTP metabolic process GO:0046039 9 9 0,000 0,04786845 0,10555842 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04786845 0,10545731 ! social behavior GO:0035176 14 9 0,000 0,04786845 0,1053564 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04786845 0,10525568 ! artery development GO:0060840 19 9 0,000 0,04786845 0,10515514 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04786845 0,10505481 ! regulation of glycolysis GO:0006110 15 9 0,000 0,04786845 0,10495466 ! response to pain GO:0048265 16 9 0,000 0,04786845 0,1048547 ! protein complex disassembly GO:0043241 17 9 0,000 0,04786845 0,10475493 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04786845 0,10465536 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04786845 0,10455597 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04786845 0,10445677 ! lung alveolus development GO:0048286 17 9 0,000 0,04786845 0,10435776 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04786845 0,10425894 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,04786845 0,1041603 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04786845 0,10406185 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04786845 0,10396359 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04786845 0,10386551 ! protein targeting to ER GO:0045047 19 9 0,000 0,04786845 0,10376761 ! endoderm development GO:0007492 12 9 0,000 0,04786845 0,1036699 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04786845 0,10357238 GO:0006688|glycosphingolipid biosynthetic process, ! arginine catabolic process GO:0006527 10 9 0,000 0,04786845 0,10347503 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04786845 0,10337787 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04786845 0,1032809 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04786845 0,1031841 ! V(D)J recombination GO:0033151 12 9 0,000 0,04786845 0,10308749 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04786845 0,10299105 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04786845 0,1028948 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04786845 0,10279873 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04786845 0,10270283 ! mannose metabolic process GO:0006013 9 9 0,000 0,04786845 0,10260712 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04786845 0,10251158 ! epithelial cell development GO:0002064 10 9 0,000 0,04786845 0,10241622 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04786845 0,10232104 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04786845 0,10222603 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04786845 0,1021312 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04786845 0,10203655 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04786845 0,10194207 ! motor axon guidance GO:0008045 14 9 0,000 0,04786845 0,10184777 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04786845 0,10175364 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04786845 0,10165968 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04786845 0,1015659 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04786845 0,10147229 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04786845 0,10137886 ! DNA ligation GO:0006266 14 9 0,000 0,04786845 0,10128559 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04786845 0,1011925 ! response to amine stimulus GO:0014075 13 9 0,000 0,04786845 0,10109957 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04786845 0,10100682 ! erythrocyte development GO:0048821 11 9 0,000 0,04786845 0,10091424 ! renal water homeostasis GO:0003091 14 9 0,000 0,04786845 0,10082183 ! postreplication repair GO:0006301 11 9 0,000 0,04786845 0,10072959 ! mRNA cleavage GO:0006379 13 9 0,000 0,04786845 0,10063751 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04786845 0,1005456 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04786845 0,10045387 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04786845 0,10036229 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04786845 0,10027089 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04786845 0,10017965 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04786845 0,10008858 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,04786845 0,09999767 ! acid secretion GO:0046717 14 9 0,000 0,04786845 0,09990693 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04786845 0,09981635 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04786845 0,09972594 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04786845 0,09963569 ! purine base metabolic process GO:0006144 18 9 0,000 0,04786845 0,0995456 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04786845 0,09945568 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,04786845 0,09936592 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04786845 0,09927632 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04786845 0,09918688 ! detection of calcium ion GO:0005513 13 9 0,000 0,04786845 0,0990976 ! blastocyst formation GO:0001825 12 9 0,000 0,04786845 0,09900849 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04786845 0,09891953 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04786845 0,09883073 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04786845 0,0987421 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04786845 0,09865362 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04786845 0,0985653 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04786845 0,09847713 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04786845 0,09838913 ! prepulse inhibition GO:0060134 14 9 0,000 0,04786845 0,09830128 ! embryonic placenta development GO:0001892 12 9 0,000 0,04786845 0,09821359 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04786845 0,09812606 ! insulin secretion GO:0030073 17 9 0,000 0,04786845 0,09803868 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04786845 0,09795146 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04786845 0,09786439 ! nucleus localization GO:0051647 15 9 0,000 0,04786845 0,09777747 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04786845 0,09769072 ! regulation of caspase activity GO:0043281 97 65 1,000 0,04872792 0,09935657 ! B cell activation GO:0042113 104 65 1,000 0,04872792 0,09926857 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,04872792 0,09918072 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,04872792 0,09909302 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,05007708 0,10174672 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,05143969 0,10442303 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,05143969 0,10433094 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,05281556 0,10702712 ! rhythmic process GO:0048511 105 68 1,000 0,05281556 0,1069329 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,05304515 0,1073033 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05304515 0,10720901 ! neuron fate specification GO:0048665 11 10 0,000 0,05304515 0,10711488 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05304515 0,10702092 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05304515 0,10692712 ! thyroid gland development GO:0030878 19 10 0,000 0,05304515 0,10683349 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05304515 0,10674003 ! synapsis GO:0007129 13 10 0,000 0,05304515 0,10664672 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05304515 0,10655358 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05304515 0,1064606 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05304515 0,10636778 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,05304515 0,10627513 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05304515 0,10618264 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,05304515 0,1060903 ! androgen metabolic process GO:0008209 13 10 0,000 0,05304515 0,10599813 ! phospholipid efflux GO:0033700 16 10 0,000 0,05304515 0,10590612 ! hippocampus development GO:0021766 19 10 0,000 0,05304515 0,10581427 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05304515 0,10572257 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05304515 0,10563104 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,05304515 0,10553966 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05304515 0,10544844 ! pathogenesis GO:0009405 13 10 0,000 0,05304515 0,10535738 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05304515 0,10526648 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05304515 0,10517573 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05304515 0,10508514 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,05304515 0,10499471 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,05304515 0,10490443 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05304515 0,1048143 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05304515 0,10472433 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05304515 0,10463452 GO:0005978|glycogen biosynthetic process, ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05304515 0,10454486 ! response to X-ray GO:0010165 16 10 0,000 0,05304515 0,10445535 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05304515 0,104366 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05304515 0,10427679 ! forebrain cell migration GO:0021885 17 10 0,000 0,05304515 0,10418774 ! lipid digestion GO:0044241 15 10 0,000 0,05304515 0,10409885 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05304515 0,1040101 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05304515 0,10392151 ! UV protection GO:0009650 14 10 0,000 0,05304515 0,10383306 ! entry into host cell GO:0030260 20 10 0,000 0,05304515 0,10374477 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05304515 0,10365663 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05304515 0,10356863 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,05304515 0,10348079 ! regulation of bone resorption GO:0045124 24 10 0,000 0,05304515 0,10339309 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05304515 0,10330555 ! regulation of organ growth GO:0046620 11 10 0,000 0,05304515 0,10321815 ! response to dsRNA GO:0043331 18 10 0,000 0,05304515 0,1031309 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05304515 0,10304379 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05304515 0,10295683 ! embryonic axis specification GO:0000578 12 10 0,000 0,05304515 0,10287002 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05304515 0,10278336 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05304515 0,10269684 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05304515 0,10261047 ! cranial nerve development GO:0021545 12 10 0,000 0,05304515 0,10252424 ! fucose catabolic process GO:0019317 16 10 0,000 0,05304515 0,10243816 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05304515 0,10235222 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05304515 0,10226643 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05304515 0,10218078 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05304515 0,10209527 ! zymogen activation GO:0031638 14 10 0,000 0,05304515 0,10200991 ! salivary gland development GO:0007431 22 10 0,000 0,05304515 0,10192469 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05304515 0,10183961 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05304515 0,10175467 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05304515 0,10166987 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05304515 0,10158522 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,05304515 0,10150071 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05304515 0,10141633 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05304515 0,1013321 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05304515 0,10124801 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05304515 0,10116405 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,05304515 0,10108024 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05304515 0,10099656 ! detection of bacterium GO:0016045 10 10 0,000 0,05304515 0,10091303 ! embryonic gut development GO:0048566 11 10 0,000 0,05304515 0,10082963 ! activation of innate immune response GO:0002218 10 10 0,000 0,05304515 0,10074637 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05304515 0,10066324 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05304515 0,10058025 ! developmental induction GO:0031128 13 10 0,000 0,05304515 0,1004974 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05304515 0,10041469 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05304515 0,10033211 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05304515 0,10024967 ! response to drug GO:0042493 108 69 1,000 0,0542045 0,10235661 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,0542045 0,10227264 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,05560634 0,10483163 ! humoral immune response GO:0006959 86 70 1,000 0,05560634 0,10474577 ! muscle cell differentiation GO:0042692 104 71 1,000 0,0570209 0,10732249 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,0570209 0,10723473 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,0570209 0,10714712 ! rRNA transcription GO:0009303 17 11 0,000 0,058194 0,10926221 ! respiratory burst GO:0045730 14 11 0,000 0,058194 0,10917309 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,058194 0,10908411 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,058194 0,10899528 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,058194 0,10890659 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,058194 0,10881805 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,058194 0,10872965 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,058194 0,1086414 ! RNA polyadenylation GO:0043631 19 11 0,000 0,058194 0,10855329 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,058194 0,10846532 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,058194 0,10837749 ! mating GO:0007618 14 11 0,000 0,058194 0,10828981 ! T cell proliferation GO:0042098 20 11 0,000 0,058194 0,10820227 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,058194 0,10811487 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,058194 0,10802761 ! bone resorption GO:0045453 16 11 0,000 0,058194 0,10794049 ! regulated secretory pathway GO:0045055 14 11 0,000 0,058194 0,10785351 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,058194 0,10776667 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,058194 0,10767997 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,058194 0,10759341 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,058194 0,10750699 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,058194 0,10742071 ! syncytium formation GO:0006949 15 11 0,000 0,058194 0,10733457 ! plasma membrane organization GO:0007009 18 11 0,000 0,058194 0,10724856 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,058194 0,10716269 ! mitotic spindle organization GO:0007052 15 11 0,000 0,058194 0,10707696 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,058194 0,10699137 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,058194 0,10690591 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,058194 0,10682059 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,058194 0,10673541 ! adult heart development GO:0007512 11 11 0,000 0,058194 0,10665036 ! temperature homeostasis GO:0001659 16 11 0,000 0,058194 0,10656545 ! L-glutamate transport GO:0015813 16 11 0,000 0,058194 0,10648067 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,058194 0,10639603 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,058194 0,10631152 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,058194 0,10622715 ! stem cell development GO:0048864 29 11 0,000 0,058194 0,10614291 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,058194 0,1060588 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,058194 0,10597483 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,058194 0,10589098 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,058194 0,10580728 ! vasoconstriction GO:0042310 15 11 0,000 0,058194 0,1057237 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,058194 0,10564026 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,058194 0,10555694 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,058194 0,10547376 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,058194 0,10539071 ! ribosome assembly GO:0042255 13 11 0,000 0,058194 0,10530779 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,058194 0,105225 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,058194 0,10514234 ! chromatin silencing GO:0006342 19 11 0,000 0,058194 0,10505982 ! nucleosome positioning GO:0016584 13 11 0,000 0,058194 0,10497742 ! regulation of isotype switching GO:0045191 19 11 0,000 0,058194 0,10489514 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,058194 0,104813 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,058194 0,10473099 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,058194 0,1046491 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,058194 0,10456735 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,058194 0,10448572 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,058194 0,10440422 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,058194 0,10432284 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,058194 0,10424159 ! male genitalia development GO:0030539 13 11 0,000 0,058194 0,10416047 ! cholesterol efflux GO:0033344 19 11 0,000 0,058194 0,10407947 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,058194 0,1039986 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,058194 0,10391786 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,058194 0,10383724 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,058194 0,10375675 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,058194 0,10367638 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,058194 0,10359613 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,058194 0,10351601 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,058194 0,10343602 ! lysogeny GO:0030069 18 11 0,000 0,058194 0,10335614 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,058194 0,10327639 ! acrosome reaction GO:0007340 13 11 0,000 0,058194 0,10319677 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,058194 0,10311726 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,05844801 0,10348762 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,05988749 0,10595478 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,06133916 0,10843971 ! blood coagulation GO:0007596 116 75 1,000 0,06280286 0,11094206 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 1,000 0,06280286 0,11085692 ! regulation of ligase activity GO:0051340 114 75 1,000 0,06280286 0,11077191 ! lactation GO:0007595 20 12 0,000 0,06331515 0,11158992 ! reproductive cellular process GO:0048610 14 12 0,000 0,06331515 0,11150447 ! tRNA modification GO:0006400 14 12 0,000 0,06331515 0,11141916 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06331515 0,11133398 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06331515 0,11124893 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,06331515 0,111164 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06331515 0,11107921 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06331515 0,11099455 ! non-recombinational repair GO:0000726 19 12 0,000 0,06331515 0,11091001 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06331515 0,1108256 ! peroxisomal transport GO:0043574 21 12 0,000 0,06331515 0,11074133 ! cartilage condensation GO:0001502 18 12 0,000 0,06331515 0,11065718 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06331515 0,11057315 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06331515 0,11048926 ! heart looping GO:0001947 15 12 0,000 0,06331515 0,11040549 ! palate development GO:0060021 15 12 0,000 0,06331515 0,11032185 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06331515 0,11023834 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06331515 0,11015495 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06331515 0,11007169 ! arginine metabolic process GO:0006525 13 12 0,000 0,06331515 0,10998855 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06331515 0,10990554 ! methionine metabolic process GO:0006555 13 12 0,000 0,06331515 0,10982266 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06331515 0,1097399 ! Golgi organization GO:0007030 18 12 0,000 0,06331515 0,10965726 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,06331515 0,10957475 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06331515 0,10949236 ! monoamine transport GO:0015844 13 12 0,000 0,06331515 0,1094101 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06331515 0,10932796 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,06331515 0,10924594 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06331515 0,10916405 ! L-amino acid transport GO:0015807 20 12 0,000 0,06331515 0,10908228 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06331515 0,10900063 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06331515 0,10891911 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06331515 0,1088377 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06331515 0,10875642 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06331515 0,10867526 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06331515 0,10859422 ! cerebellum development GO:0021549 13 12 0,000 0,06331515 0,1085133 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06331515 0,1084325 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06331515 0,10835182 ! histone methylation GO:0016571 15 12 0,000 0,06331515 0,10827126 ! autonomic nervous system development GO:0048483 23 12 0,000 0,06331515 0,10819082 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06331515 0,1081105 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06331515 0,1080303 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06331515 0,10795022 ! intestinal absorption GO:0050892 19 12 0,000 0,06331515 0,10787025 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06331515 0,10779041 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06331515 0,10771068 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,06331515 0,10763107 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06331515 0,10755158 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,06331515 0,10747221 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06331515 0,10739295 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06331515 0,10731381 ! microspike assembly GO:0030035 23 12 0,000 0,06331515 0,10723479 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06331515 0,10715588 ! response to cold GO:0009409 14 12 0,000 0,06331515 0,10707709 ! amine biosynthetic process GO:0009309 97 76 1,000 0,06427841 0,10862626 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,06576564 0,11105798 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,06726439 0,11350558 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,06726439 0,11342237 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06840874 0,11526748 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06840874 0,11518309 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06840874 0,11509883 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06840874 0,1150147 ! water transport GO:0006833 17 13 0,000 0,06840874 0,11493068 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06840874 0,11484679 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06840874 0,11476302 ! lipid localization GO:0010876 24 13 0,000 0,06840874 0,11467938 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06840874 0,11459585 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06840874 0,11451245 ! organelle fusion GO:0048284 28 13 0,000 0,06840874 0,11442917 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06840874 0,11434601 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06840874 0,11426297 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,06840874 0,11418005 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06840874 0,11409725 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06840874 0,11401457 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06840874 0,11393201 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06840874 0,11384957 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06840874 0,11376725 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06840874 0,11368505 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06840874 0,11360297 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06840874 0,113521 ! NAD metabolic process GO:0019674 21 13 0,000 0,06840874 0,11343915 ! exocrine system development GO:0035272 27 13 0,000 0,06840874 0,11335743 ! bone mineralization GO:0030282 15 13 0,000 0,06840874 0,11327581 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06840874 0,11319432 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06840874 0,11311295 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06840874 0,11303169 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06840874 0,11295054 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06840874 0,11286952 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06840874 0,11278861 ! genitalia development GO:0048806 15 13 0,000 0,06840874 0,11270781 ! regulation of cellular pH GO:0030641 20 13 0,000 0,06840874 0,11262713 ! tissue regeneration GO:0042246 21 13 0,000 0,06840874 0,11254657 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06840874 0,11246612 ! cofactor transport GO:0051181 19 13 0,000 0,06840874 0,11238579 ! NADP metabolic process GO:0006739 18 13 0,000 0,06840874 0,11230557 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06840874 0,11222547 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06840874 0,11214548 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06840874 0,1120656 ! gas transport GO:0015669 18 13 0,000 0,06840874 0,11198584 ! regulation of RNA stability GO:0043487 28 13 0,000 0,06840874 0,11190619 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06840874 0,11182666 ! regulation of axon extension GO:0030516 23 13 0,000 0,06840874 0,11174723 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06840874 0,11166793 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06840874 0,11158873 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06840874 0,11150964 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06840874 0,11143067 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06840874 0,11135181 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,0687745 0,111868 ! T cell activation GO:0042110 134 79 1,000 0,0687745 0,11178894 ! regulation of lyase activity GO:0051339 133 79 1,000 0,0687745 0,11170999 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,07029579 0,11410044 GO:0010498|proteasomal protein catabolic process, ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,07182811 0,11650539 ! hemostasis GO:0007599 125 81 1,000 0,07182811 0,11642329 ! response to protein stimulus GO:0051789 111 81 1,000 0,07182811 0,1163413 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,07182811 0,11625943 GO:0002696|positive regulation of leukocyte activation, ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,07347493 0,1188413 ! superoxide anion generation GO:0042554 18 14 0,000 0,07347493 0,11875779 ! neuron maturation GO:0042551 21 14 0,000 0,07347493 0,11867439 ! regulation of S phase GO:0033261 18 14 0,000 0,07347493 0,11859111 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,07347493 0,11850795 ! myotube differentiation GO:0014902 21 14 0,000 0,07347493 0,1184249 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07347493 0,11834197 ! inositol metabolic process GO:0006020 20 14 0,000 0,07347493 0,11825915 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07347493 0,11817645 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07347493 0,11809387 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07347493 0,1180114 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07347493 0,11792905 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07347493 0,11784681 ! response to cAMP GO:0051591 19 14 0,000 0,07347493 0,11776469 ! limbic system development GO:0021761 25 14 0,000 0,07347493 0,11768268 ! startle response GO:0001964 21 14 0,000 0,07347493 0,11760079 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07347493 0,11751901 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,07347493 0,11743734 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07347493 0,11735578 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,07347493 0,11727434 ! glycine metabolic process GO:0006544 22 14 0,000 0,07347493 0,11719302 ! pituitary gland development GO:0021983 23 14 0,000 0,07347493 0,1171118 ! cellular response to starvation GO:0009267 21 14 0,000 0,07347493 0,1170307 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,07347493 0,11694971 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,07347493 0,11686883 ! regulation of heart rate GO:0002027 23 14 0,000 0,07347493 0,11678806 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07347493 0,11670741 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,07347493 0,11662687 ! embryo implantation GO:0007566 27 14 0,000 0,07347493 0,11654643 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,07347493 0,11646611 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,07347493 0,1163859 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07347493 0,1163058 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,07347493 0,11622581 ! axon cargo transport GO:0008088 27 14 0,000 0,07347493 0,11614593 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07347493 0,11606616 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07347493 0,1159865 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,07347493 0,11590695 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07347493 0,11582751 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07347493 0,11574817 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07347493 0,11566895 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07347493 0,11558983 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07347493 0,11551082 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07347493 0,11543192 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,07347493 0,11535313 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,07347493 0,11527444 ! muscle maintenance GO:0046716 19 14 0,000 0,07347493 0,11519586 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07347493 0,11511739 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,07347493 0,11503903 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07347493 0,11496077 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07347493 0,11488262 ! cell killing GO:0001906 20 14 0,000 0,07347493 0,11480457 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,07347493 0,11472663 ! cilium assembly GO:0042384 20 14 0,000 0,07347493 0,1146488 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07347493 0,11457107 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,07492516 0,1167533 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,07492516 0,11667426 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,07492516 0,11659532 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,07806439 0,12139831 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,07851385 0,12201476 ! positive regulation of cell size GO:0045793 20 15 0,000 0,07851385 0,12193238 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07851385 0,1218501 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,07851385 0,12176794 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,07851385 0,12168588 ! skin development GO:0043588 25 15 0,000 0,07851385 0,12160394 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,07851385 0,12152211 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07851385 0,12144038 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,07851385 0,12135877 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07851385 0,12127727 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07851385 0,12119587 ! adult walking behavior GO:0007628 25 15 0,000 0,07851385 0,12111459 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07851385 0,12103341 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,07851385 0,12095234 ! myoblast differentiation GO:0045445 27 15 0,000 0,07851385 0,12087139 ! centrosome cycle GO:0007098 16 15 0,000 0,07851385 0,12079053 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07851385 0,12070979 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,07851385 0,12062916 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07851385 0,12054863 ! cerebral cortex development GO:0021987 29 15 0,000 0,07851385 0,12046821 ! response to osmotic stress GO:0006970 22 15 0,000 0,07851385 0,1203879 ! vesicle coating GO:0006901 25 15 0,000 0,07851385 0,12030769 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,07851385 0,1202276 ! DNA integration GO:0015074 22 15 0,000 0,07851385 0,1201476 ! peptide secretion GO:0002790 27 15 0,000 0,07851385 0,12006772 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07851385 0,11998794 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07851385 0,11990827 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,07851385 0,1198287 ! neuron recognition GO:0008038 22 15 0,000 0,07851385 0,11974924 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,07851385 0,11966988 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07851385 0,11959063 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07851385 0,11951148 ! biomineral formation GO:0031214 18 15 0,000 0,07851385 0,11943244 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07851385 0,1193535 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,07851385 0,11927467 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,07851385 0,11919594 ! dopamine metabolic process GO:0042417 30 15 0,000 0,07851385 0,11911732 ! organic cation transport GO:0015695 19 15 0,000 0,07851385 0,11903879 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07851385 0,11896038 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,07851385 0,11888206 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,07851385 0,11880385 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,07851385 0,11872574 ! peptide hormone processing GO:0016486 19 15 0,000 0,07851385 0,11864773 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,07851385 0,11856983 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,07964943 0,12020583 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,08124454 0,12253275 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 1,000 0,08124454 0,12245245 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,08124454 0,12237226 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,08284957 0,12470812 ! protein secretion GO:0009306 27 16 0,000 0,08352565 0,12564356 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,08352565 0,12556144 ! hormone secretion GO:0046879 25 16 0,000 0,08352565 0,12547942 ! bone remodeling GO:0046849 24 16 0,000 0,08352565 0,12539752 ! endothelial cell migration GO:0043542 22 16 0,000 0,08352565 0,12531572 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,08352565 0,12523403 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08352565 0,12515244 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,08352565 0,12507096 ! glial cell development GO:0021782 24 16 0,000 0,08352565 0,12498959 ! patterning of blood vessels GO:0001569 24 16 0,000 0,08352565 0,12490832 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,08352565 0,12482716 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,08352565 0,1247461 ! protein polyubiquitination GO:0000209 26 16 0,000 0,08352565 0,12466515 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,08352565 0,12458431 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,08352565 0,12450356 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,08352565 0,12442293 ! fructose metabolic process GO:0006000 20 16 0,000 0,08352565 0,12434239 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,08352565 0,12426197 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,08352565 0,12418164 ! protein export from nucleus GO:0006611 24 16 0,000 0,08352565 0,12410142 ! negative regulation of immune response GO:0050777 28 16 0,000 0,08352565 0,1240213 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,08352565 0,12394129 ! DNA replication initiation GO:0006270 25 16 0,000 0,08352565 0,12386138 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,08352565 0,12378157 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,08352565 0,12370187 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,08352565 0,12362226 ! diencephalon development GO:0021536 25 16 0,000 0,08352565 0,12354276 ! neural crest cell migration GO:0001755 24 16 0,000 0,08352565 0,12346337 ! G1 phase GO:0051318 27 16 0,000 0,08352565 0,12338407 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,08352565 0,12330488 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,08352565 0,12322579 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,08352565 0,12314679 ! steroid catabolic process GO:0006706 22 16 0,000 0,08352565 0,1230679 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,08352565 0,12298912 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,08352565 0,12291043 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,08352565 0,12283184 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,08352565 0,12275335 ! sperm-egg recognition GO:0035036 16 16 0,000 0,08352565 0,12267497 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,08352565 0,12259668 ! nerve development GO:0021675 18 16 0,000 0,08352565 0,12251849 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,08352565 0,12244041 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,08446437 0,12373761 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,08446437 0,12365885 ! leukocyte differentiation GO:0002521 143 90 1,000 0,08608879 0,12595688 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08851048 0,12941774 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,08851048 0,12933552 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08851048 0,1292534 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,08851048 0,12917139 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,08851048 0,12908948 ! glycerol metabolic process GO:0006071 20 17 0,000 0,08851048 0,12900768 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08851048 0,12892597 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08851048 0,12884437 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08851048 0,12876288 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08851048 0,12868149 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08851048 0,1286002 ! memory GO:0007613 25 17 0,000 0,08851048 0,12851901 ! keratinization GO:0031424 17 17 0,000 0,08851048 0,12843793 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08851048 0,12835694 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,08851048 0,12827606 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08851048 0,12819528 GO:0016101|diterpenoid metabolic process, ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,08851048 0,12811461 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08851048 0,12803403 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,08851048 0,12795356 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,08851048 0,12787319 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08851048 0,12779291 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,08851048 0,12771274 ! membrane budding GO:0006900 29 17 0,000 0,08851048 0,12763267 ! heme metabolic process GO:0042168 27 17 0,000 0,08851048 0,1275527 ! actin filament bundle formation GO:0051017 26 17 0,000 0,08851048 0,12747283 ! neuromuscular junction development GO:0007528 23 17 0,000 0,08851048 0,12739306 ! body fluid secretion GO:0007589 27 17 0,000 0,08851048 0,12731339 ! stem cell differentiation GO:0048863 36 17 0,000 0,08851048 0,12723382 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08851048 0,12715435 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08851048 0,12707498 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08851048 0,1269957 ! sensory perception of pain GO:0019233 23 17 0,000 0,08851048 0,12691653 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,08851048 0,12683745 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,08851048 0,12675848 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,08851048 0,1266796 ! synaptogenesis GO:0007416 24 17 0,000 0,08851048 0,12660082 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08851048 0,12652213 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08851048 0,12644355 ! cell-cell junction organization GO:0045216 25 17 0,000 0,08851048 0,12636506 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,08851048 0,12628667 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,08851048 0,12620838 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,08851048 0,12613018 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08851048 0,12605208 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,08936588 0,12719153 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,08936588 0,12711287 ! cell fate commitment GO:0045165 141 92 1,000 0,08936588 0,12703431 ! sulfur metabolic process GO:0006790 118 92 1,000 0,08936588 0,12695585 ! response to oxidative stress GO:0006979 141 94 1,000 0,09267966 0,13158223 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,09346849 0,13262031 ! positive regulation of translation GO:0045727 28 18 0,000 0,09346849 0,13253854 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,09346849 0,13245688 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,09346849 0,13237532 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,09346849 0,13229386 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,09346849 0,13221249 ! cAMP metabolic process GO:0046058 33 18 0,000 0,09346849 0,13213123 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,09346849 0,13205007 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,09346849 0,13196901 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,09346849 0,13188805 ! axis specification GO:0009798 26 18 0,000 0,09346849 0,13180718 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,09346849 0,13172642 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,09346849 0,13164575 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,09346849 0,13156519 ! glutamine metabolic process GO:0006541 23 18 0,000 0,09346849 0,13148472 ! response to retinoic acid GO:0032526 25 18 0,000 0,09346849 0,13140435 ! pigmentation during development GO:0048066 31 18 0,000 0,09346849 0,13132408 ! central nervous system neuron development GO:0021954 30 18 0,000 0,09346849 0,1312439 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,09346849 0,13116383 ! fucose metabolic process GO:0006004 26 18 0,000 0,09346849 0,13108385 ! response to fungus GO:0009620 19 18 0,000 0,09346849 0,13100397 ! peptide cross-linking GO:0018149 31 18 0,000 0,09346849 0,13092419 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,09346849 0,1308445 ! heart process GO:0003015 27 18 0,000 0,09346849 0,13076491 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,09346849 0,13068542 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,09346849 0,13060602 ! visual learning GO:0008542 35 18 0,000 0,09346849 0,13052672 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,09346849 0,13044752 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,09346849 0,13036841 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,09346849 0,1302894 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,09346849 0,13021049 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,09346849 0,13013167 ! vitamin transport GO:0051180 24 18 0,000 0,09346849 0,13005294 ! hormone transport GO:0009914 27 18 0,000 0,09346849 0,12997431 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,09346849 0,12989578 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,09346849 0,12981734 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,09346849 0,129739 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,09346849 0,12966075 ! cell-cell recognition GO:0009988 20 18 0,000 0,09346849 0,12958259 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,09346849 0,12950453 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,09346849 0,12942656 ! regulation of glucose import GO:0046324 21 18 0,000 0,09346849 0,12934869 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,09346849 0,12927091 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,09346849 0,12919322 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,09346849 0,12911563 ! angiogenesis GO:0001525 149 95 1,000 0,09434995 0,13025503 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,09602898 0,13249349 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,0977166 0,13474112 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,0983998 0,13560188 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,0983998 0,13552068 ! positive regulation of ossification GO:0045778 30 19 0,000 0,0983998 0,13543958 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,0983998 0,13535858 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,0983998 0,13527767 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,0983998 0,13519686 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,0983998 0,13511614 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,0983998 0,13503553 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,0983998 0,134955 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,0983998 0,13487458 ! sensory perception of taste GO:0050909 23 19 0,000 0,0983998 0,13479425 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,0983998 0,13471401 ! smooth muscle contraction GO:0006939 36 19 0,000 0,0983998 0,13463387 ! peroxisome organization GO:0007031 29 19 0,000 0,0983998 0,13455383 ! digestive system process GO:0022600 30 19 0,000 0,0983998 0,13447388 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,0983998 0,13439403 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,0983998 0,13431427 ! response to vitamin A GO:0033189 26 19 0,000 0,0983998 0,1342346 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,0983998 0,13415503 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,0983998 0,13407556 ! response to starvation GO:0042594 30 19 0,000 0,0983998 0,13399618 ! sex determination GO:0007530 29 19 0,000 0,0983998 0,13391689 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,0983998 0,13383769 ! plasma membrane fusion GO:0045026 23 19 0,000 0,0983998 0,13375859 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,0983998 0,13367959 ! cytolysis GO:0019835 20 19 0,000 0,0983998 0,13360067 ! vasodilation GO:0042311 33 19 0,000 0,0983998 0,13352185 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,0983998 0,13344313 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,0983998 0,13336449 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,0983998 0,13328595 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,0983998 0,1332075 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,0983998 0,13312914 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,0983998 0,13305088 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,0983998 0,1329727 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,0983998 0,13289462 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,0983998 0,13281663 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,0983998 0,13273873 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,0983998 0,13266093 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,0983998 0,13258321 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,0983998 0,13250559 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,0983998 0,13242805 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,10111709 0,13600544 ! regulation of translation GO:0006417 151 100 1,000 0,10282967 0,13822808 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,10282967 0,13814734 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,10282967 0,13806669 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,10330457 0,1386234 ! iron ion transport GO:0006826 37 20 0,000 0,10330457 0,13854257 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,10330457 0,13846184 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,10330457 0,1383812 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,10330457 0,13830065 ! response to vitamin GO:0033273 29 20 0,000 0,10330457 0,13822019 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,10330457 0,13813983 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,10330457 0,13805957 ! spinal cord development GO:0021510 31 20 0,000 0,10330457 0,13797939 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,10330457 0,13789931 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,10330457 0,13781932 ! chromosome condensation GO:0030261 31 20 0,000 0,10330457 0,13773943 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,10330457 0,13765963 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,10330457 0,13757992 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,10330457 0,1375003 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,10330457 0,13742077 ! pallium development GO:0021543 38 20 0,000 0,10330457 0,13734134 ! DNA modification GO:0006304 28 20 0,000 0,10330457 0,137262 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,10330457 0,13718275 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,10330457 0,13710359 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,10330457 0,13702452 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,10330457 0,13694554 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,10330457 0,13686666 ! collagen catabolic process GO:0030574 25 20 0,000 0,10330457 0,13678786 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,10330457 0,13670916 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,10330457 0,13663054 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,10330457 0,13655202 ! alditol metabolic process GO:0019400 24 20 0,000 0,10330457 0,13647359 ! actin filament-based movement GO:0030048 34 20 0,000 0,10330457 0,13639524 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,10818294 0,14275431 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,10818294 0,14267246 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,10818294 0,14259069 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,10818294 0,14250903 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,10818294 0,14242745 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,10818294 0,14234597 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,10818294 0,14226459 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,10818294 0,14218329 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,10818294 0,14210209 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,10818294 0,14202098 ! vesicle docking GO:0048278 27 21 0,000 0,10818294 0,14193997 ! phototransduction GO:0007602 25 21 0,000 0,10818294 0,14185904 ! dendrite development GO:0016358 35 21 0,000 0,10818294 0,14177821 ! visual behavior GO:0007632 39 21 0,000 0,10818294 0,14169747 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,10818294 0,14161683 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,10818294 0,14153627 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,10818294 0,14145581 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,10818294 0,14137543 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,10818294 0,14129515 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,10818294 0,14121496 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,10818294 0,14113486 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,10818294 0,14105485 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,10818294 0,14097494 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,10818294 0,14089511 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,10818294 0,14081537 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,10818294 0,14073573 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,10818294 0,14065617 ! fatty acid transport GO:0015908 30 21 0,000 0,10818294 0,1405767 ! immunoglobulin production GO:0002377 33 21 0,000 0,10818294 0,14049732 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,10818294 0,14041804 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,10818294 0,14033884 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,10818294 0,14025973 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,10818294 0,14018071 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,10818294 0,14010178 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,10818294 0,14002294 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,10818294 0,13994419 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,10818294 0,13986552 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,10818294 0,13978694 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,10818294 0,13970846 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,10818294 0,13963006 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,10818294 0,13955175 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,11303505 0,14572904 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,11303505 0,1456474 ! viral genome replication GO:0019079 29 22 0,000 0,11303505 0,14556585 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,11303505 0,14548439 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,11303505 0,14540302 ! leukocyte adhesion GO:0007159 38 22 0,000 0,11303505 0,14532175 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,11303505 0,14524056 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,11303505 0,14515947 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,11303505 0,14507846 ! vasculogenesis GO:0001570 33 22 0,000 0,11303505 0,14499755 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,11303505 0,14491673 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,11303505 0,14483599 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,11303505 0,14475535 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,11303505 0,14467479 ! lysosome organization GO:0007040 37 22 0,000 0,11303505 0,14459433 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,11303505 0,14451396 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,11303505 0,14443367 ! regulation of behavior GO:0050795 38 22 0,000 0,11303505 0,14435347 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,11303505 0,14427337 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,11303505 0,14419335 ! membrane depolarization GO:0051899 35 22 0,000 0,11303505 0,14411342 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,11303505 0,14403358 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,11303505 0,14395382 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,11303505 0,14387416 ! blastocyst development GO:0001824 37 22 0,000 0,11303505 0,14379458 ! neural tube closure GO:0001843 33 22 0,000 0,11303505 0,14371509 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,11303505 0,14363569 ! protein tetramerization GO:0051262 39 22 0,000 0,11303505 0,14355638 ! neuron fate commitment GO:0048663 32 23 0,000 0,11786103 0,14960285 ! embryonic pattern specification GO:0009880 31 23 0,000 0,11786103 0,14952033 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,11786103 0,14943791 ! myelination GO:0042552 35 23 0,000 0,11786103 0,14935557 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,11786103 0,14927333 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,11786103 0,14919118 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,11786103 0,14910911 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,11786103 0,14902714 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,11786103 0,14894526 ! vesicle targeting GO:0006903 32 23 0,000 0,11786103 0,14886346 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,11786103 0,14878176 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,11786103 0,14870015 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,11786103 0,14861862 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,11786103 0,14853719 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,11786103 0,14845584 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,11786103 0,14837459 ! cell fate determination GO:0001709 45 23 0,000 0,11786103 0,14829342 ! pentose metabolic process GO:0019321 31 23 0,000 0,11786103 0,14821234 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,11786103 0,14813135 ! spermatid development GO:0007286 33 23 0,000 0,11786103 0,14805045 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,11786103 0,14796963 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,11786103 0,14788891 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,11786103 0,14780827 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,11786103 0,14772772 ! telomere organization GO:0032200 32 23 0,000 0,11786103 0,14764726 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,11786103 0,14756688 ! regulation of amine transport GO:0051952 38 23 0,000 0,11786103 0,1474866 ! liver development GO:0001889 40 23 0,000 0,11786103 0,1474064 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,12266103 0,15332629 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,12266103 0,153243 ! initiation of viral infection GO:0019059 42 24 0,000 0,12266103 0,15315981 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,12266103 0,15307671 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,12266103 0,15299369 ! superoxide metabolic process GO:0006801 32 24 0,000 0,12266103 0,15291077 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,12266103 0,15282793 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,12266103 0,15274519 ! fat cell differentiation GO:0045444 37 24 0,000 0,12266103 0,15266254 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,12266103 0,15257997 ! sperm motility GO:0030317 27 24 0,000 0,12266103 0,1524975 ! vacuole organization GO:0007033 39 24 0,000 0,12266103 0,15241511 ! neural crest cell development GO:0014032 39 24 0,000 0,12266103 0,15233281 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,12266103 0,1522506 ! negative regulation of cell development GO:0010721 56 24 0,000 0,12266103 0,15216848 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,12266103 0,15208645 ! base-excision repair GO:0006284 31 24 0,000 0,12266103 0,15200451 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,12266103 0,15192265 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,12266103 0,15184089 ! glutathione metabolic process GO:0006749 29 24 0,000 0,12266103 0,15175921 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,12266103 0,15167762 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,12266103 0,15159611 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,12266103 0,1515147 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,12743518 0,15732739 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,12743518 0,15724299 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,12743518 0,15715867 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,12743518 0,15707445 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,12743518 0,15699032 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,12743518 0,15690628 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,12743518 0,15682232 ! peptide transport GO:0015833 43 25 0,000 0,12743518 0,15673846 ! iron ion homeostasis GO:0055072 39 25 0,000 0,12743518 0,15665469 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,12743518 0,15657101 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,12743518 0,15648741 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,12743518 0,15640391 ! phospholipid transport GO:0015914 35 25 0,000 0,12743518 0,15632049 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,12743518 0,15623717 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,12743518 0,15615393 ! detection of light stimulus GO:0009583 30 25 0,000 0,12743518 0,15607078 ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,12743518 0,15598772 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,13218363 0,16171402 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,13218363 0,16162805 ! translational initiation GO:0006413 43 26 0,000 0,13218363 0,16154217 ! regulation of pH GO:0006885 36 26 0,000 0,13218363 0,16145638 ! circadian rhythm GO:0007623 42 26 0,000 0,13218363 0,16137068 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,13218363 0,16128507 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,13218363 0,16119955 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,13218363 0,16111413 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,13218363 0,16102879 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,13218363 0,16094354 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,13218363 0,16085839 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,13218363 0,16077332 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,13218363 0,16068835 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,13218363 0,16060346 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,13690651 0,16625395 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,13690651 0,16616621 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,13690651 0,16607857 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,13690651 0,16599102 ! membrane docking GO:0022406 39 27 0,000 0,13690651 0,16590357 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,13690651 0,16581621 ! catechol metabolic process GO:0009712 43 27 0,000 0,13690651 0,16572893 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,13690651 0,16564175 ! acute-phase response GO:0006953 42 27 0,000 0,13690651 0,16555467 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,13690651 0,16546767 ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,13690651 0,16538076 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,13690651 0,16529395 ! natural killer cell activation GO:0030101 35 27 0,000 0,13690651 0,16520723 ! lipid oxidation GO:0034440 38 27 0,000 0,13690651 0,16512059 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,13690651 0,16503405 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,13690651 0,1649476 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,13690651 0,16486124 ! gene silencing GO:0016458 41 27 0,000 0,13690651 0,16477497 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,14160395 0,17033948 ! phenol metabolic process GO:0018958 44 28 0,000 0,14160395 0,17025044 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,14160395 0,17016149 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,14160395 0,17007263 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,14160395 0,16998387 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,14160395 0,1698952 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,14160395 0,16980662 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,14160395 0,16971813 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,14160395 0,16962974 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,14160395 0,16954143 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,14160395 0,16945322 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,14160395 0,1693651 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,14160395 0,16927708 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,14160395 0,16918914 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,14160395 0,1691013 ! mesoderm formation GO:0001707 46 28 0,000 0,14160395 0,16901354 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,14160395 0,16892588 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,14160395 0,16883831 ! ensheathment of neurons GO:0007272 43 28 0,000 0,14160395 0,16875083 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,14160395 0,16866344 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,14160395 0,16857614 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,14160395 0,16848893 ! neural tube formation GO:0001841 41 28 0,000 0,14160395 0,16840181 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,14160395 0,16831478 ! placenta development GO:0001890 37 28 0,000 0,14160395 0,16822784 ! regulation of innate immune response GO:0045088 38 29 0,000 0,1462761 0,17368871 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,1462761 0,17359909 ! protein targeting to membrane GO:0006612 53 29 0,000 0,1462761 0,17350956 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,1462761 0,17342012 ! mismatch repair GO:0006298 34 29 0,000 0,1462761 0,17333077 ! formation of primary germ layer GO:0001704 48 29 0,000 0,1462761 0,17324152 ! telencephalon development GO:0021537 52 29 0,000 0,1462761 0,17315236 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,1462761 0,17306329 ! eye morphogenesis GO:0048592 51 29 0,000 0,1462761 0,17297431 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,1462761 0,17288542 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,15092308 0,17828613 ! collagen metabolic process GO:0032963 40 30 0,000 0,15092308 0,1781946 ! organic anion transport GO:0015711 51 30 0,000 0,15092308 0,17810317 ! cholesterol transport GO:0030301 46 30 0,000 0,15092308 0,17801184 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,15092308 0,1779206 ! spliceosome assembly GO:0000245 49 30 0,000 0,15092308 0,17782945 ! spindle organization GO:0007051 37 30 0,000 0,15092308 0,1777384 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,15092308 0,17764743 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,15092308 0,17755657 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,15092308 0,17746579 ! ceramide metabolic process GO:0006672 43 30 0,000 0,15092308 0,17737511 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,15092308 0,17728452 ! adult locomotory behavior GO:0008344 47 30 0,000 0,15092308 0,17719402 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,15092308 0,17710362 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,15092308 0,1770133 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,15092308 0,17692308 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,15092308 0,17683295 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,15092308 0,17674292 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,15554503 0,18206289 ! mammary gland development GO:0030879 57 31 0,000 0,15554503 0,18197028 ! glial cell differentiation GO:0010001 55 31 0,000 0,15554503 0,18187777 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,15554503 0,18178535 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,15554503 0,18169303 ! odontogenesis GO:0042476 50 31 0,000 0,15554503 0,1816008 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,15554503 0,18150866 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,15554503 0,18141662 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,15554503 0,18132467 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,15554503 0,18123281 ! cell fate specification GO:0001708 37 31 0,000 0,15554503 0,18114105 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,15554503 0,18104938 GO:0060326|cell chemotaxis, ! RNA modification GO:0009451 40 31 0,000 0,15554503 0,1809578 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,16014209 0,18621173 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,16014209 0,18611764 ! meiosis I GO:0007127 52 32 0,000 0,16014209 0,18602364 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,16014209 0,18592974 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,16014209 0,18583593 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,16014209 0,18574221 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,16014209 0,18564859 ! peripheral nervous system development GO:0007422 53 32 0,000 0,16014209 0,18555507 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,16014209 0,18546163 ! cytokine production GO:0001816 44 32 0,000 0,16014209 0,1853683 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,16014209 0,18527505 ! vesicle localization GO:0051648 47 32 0,000 0,16014209 0,1851819 ! RNA export from nucleus GO:0006405 44 33 0,000 0,16471438 0,19037341 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,16471438 0,19027779 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,16471438 0,19018227 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,16471438 0,19008684 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,16471438 0,18999151 ! sister chromatid segregation GO:0000819 46 33 0,000 0,16471438 0,18989628 ! ear morphogenesis GO:0042471 42 33 0,000 0,16471438 0,18980114 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,16471438 0,1897061 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,16471438 0,18961115 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,16471438 0,1895163 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,16471438 0,18942154 ! lipid homeostasis GO:0055088 55 33 0,000 0,16471438 0,18932688 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,16471438 0,18923231 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,16471438 0,18913783 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,16471438 0,18904345 ! cytokinesis GO:0000910 52 33 0,000 0,16471438 0,18894917 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,16471438 0,18885497 ! mRNA catabolic process GO:0006402 48 34 0,000 0,16926204 0,19397245 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,16926204 0,19387585 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,16926204 0,19377934 ! feeding behavior GO:0007631 45 34 0,000 0,16926204 0,19368293 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,16926204 0,19358662 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,16926204 0,19349041 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,16926204 0,19339429 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,16926204 0,19329826 ! neuron migration GO:0001764 46 34 0,000 0,16926204 0,19320233 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,16926204 0,1931065 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,16926204 0,19301076 ! polyol metabolic process GO:0019751 44 34 0,000 0,16926204 0,19291511 ! aerobic respiration GO:0009060 47 34 0,000 0,16926204 0,19281956 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,16926204 0,19272411 ! embryonic organ development GO:0048568 45 34 0,000 0,16926204 0,19262875 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,16926204 0,19253348 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,1737852 0,1975808 ! Notch signaling pathway GO:0007219 56 35 0,000 0,1737852 0,19748319 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,1737852 0,19738566 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,1737852 0,19728824 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,1737852 0,19719091 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,1737852 0,19709367 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,1737852 0,19699653 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,1737852 0,19689949 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,1737852 0,19680254 ! glycogen metabolic process GO:0005977 48 35 0,000 0,1737852 0,19670569 ! protein homooligomerization GO:0051260 52 35 0,000 0,1737852 0,19660894 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,17828399 0,2015994 ! organic ether metabolic process GO:0018904 46 36 0,000 0,17828399 0,20150034 ! neural tube development GO:0021915 50 36 0,000 0,17828399 0,20140137 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,17828399 0,2013025 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,17828399 0,20120372 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,17828399 0,20110504 ! glucan metabolic process GO:0044042 49 36 0,000 0,17828399 0,20100646 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,18275855 0,20595034 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,18275855 0,20584949 ! learning GO:0007612 67 37 0,000 0,18275855 0,20574873 ! ion transmembrane transport GO:0034220 56 37 0,000 0,18275855 0,20564807 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,18275855 0,20554751 ! amino acid activation GO:0043038 52 37 0,000 0,18275855 0,20544704 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,18275855 0,20534668 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,18720899 0,21024447 ! gliogenesis GO:0042063 71 38 0,000 0,18720899 0,21014186 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,18720899 0,21003935 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,18720899 0,20993694 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,18720899 0,20983463 ! phagocytosis GO:0006909 60 38 0,000 0,18720899 0,20973242 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,19163544 0,21458691 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,19163544 0,21448249 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,19163544 0,21437817 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,19163544 0,21427395 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,19163544 0,21416984 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,19163544 0,21406582 ! JNK cascade GO:0007254 54 39 0,000 0,19163544 0,2139619 ! synapse organization GO:0050808 55 39 0,000 0,19163544 0,21385809 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,19603805 0,21866514 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,19603805 0,21855914 ! regulation of tube size GO:0035150 60 40 0,000 0,19603805 0,21845325 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,19603805 0,21834746 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,19603805 0,21824178 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,19603805 0,21813619 ! peptide metabolic process GO:0006518 56 40 0,000 0,19603805 0,21803071 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,19603805 0,21792533 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,19603805 0,21782005 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,19603805 0,21771488 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,19603805 0,2176098 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,20041693 0,22236321 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,20041693 0,22225599 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,20041693 0,22214888 ! glucose transport GO:0015758 52 41 0,000 0,20041693 0,22204187 ! striated muscle contraction GO:0006941 62 41 0,000 0,20041693 0,22193497 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,20041693 0,22182817 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,20041693 0,22172147 ! biopolymer methylation GO:0043414 62 41 0,000 0,20041693 0,22161487 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,20041693 0,22150838 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,2047722 0,22621329 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,2047722 0,22610469 ! hexose transport GO:0008645 54 42 0,000 0,2047722 0,22599619 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,2047722 0,2258878 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,2047722 0,22577952 ! excretion GO:0007588 63 42 0,000 0,2047722 0,22567133 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,2047722 0,22556325 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,2047722 0,22545528 ! regulation of cell shape GO:0008360 78 42 0,000 0,2047722 0,2253474 ! leukocyte migration GO:0050900 60 43 0,000 0,20910401 0,23000441 ! neuromuscular process GO:0050905 79 43 0,000 0,20910401 0,22989446 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,20910401 0,22978462 ! tRNA processing GO:0008033 49 43 0,000 0,20910401 0,22967489 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,20910401 0,22956526 ! methylation GO:0032259 64 43 0,000 0,20910401 0,22945573 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,21341246 0,23407185 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,21341246 0,23396028 ! glycolysis GO:0006096 53 44 0,000 0,21341246 0,23384881 ! regulation of action potential GO:0001508 71 44 0,000 0,21341246 0,23373746 ! regulation of ion transport GO:0043269 57 44 0,000 0,21341246 0,23362621 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,21341246 0,23351506 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,21341246 0,23340402 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,21341246 0,23329309 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,21341246 0,23318226 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,21341246 0,23307154 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,21341246 0,23296092 ! RNA catabolic process GO:0006401 64 45 0,000 0,21769769 0,23752594 ! positive regulation of defense response GO:0031349 59 45 0,000 0,21769769 0,23741332 ! regulation of translational initiation GO:0006446 64 45 0,000 0,21769769 0,2373008 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,21769769 0,23718839 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,21769769 0,23707608 ! cell recognition GO:0008037 58 45 0,000 0,21769769 0,23696388 ! cell maturation GO:0048469 60 45 0,000 0,21769769 0,23685179 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,22195982 0,24137474 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,22195982 0,24126067 ! cell redox homeostasis GO:0045454 63 46 0,000 0,22195982 0,24114671 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,22195982 0,24103285 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,22195982 0,2409191 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,22619897 0,24540454 ! viral infectious cycle GO:0019058 71 47 0,000 0,22619897 0,24528884 ! endocrine system development GO:0035270 83 47 0,000 0,22619897 0,24517324 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,22619897 0,24505776 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,22619897 0,24494238 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,22619897 0,24482712 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,22619897 0,24471196 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,22619897 0,24459691 ! chloride transport GO:0006821 67 48 0,000 0,23041526 0,24903905 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,23041526 0,24892208 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,23041526 0,24880521 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,23041526 0,24868846 ! gastrulation GO:0007369 73 48 0,000 0,23041526 0,24857181 ! heart morphogenesis GO:0003007 65 48 0,000 0,23041526 0,24845527 ! regulation of DNA replication GO:0006275 75 48 0,000 0,23041526 0,24833885 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,23041526 0,24822253 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,23041526 0,24810632 ! regulation of endocytosis GO:0030100 63 48 0,000 0,23041526 0,24799022 ! nuclear export GO:0051168 69 48 0,000 0,23041526 0,24787423 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,23041526 0,24775835 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,23041526 0,24764257 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,23460882 0,2520319 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,23460882 0,25191424 ! sensory perception of smell GO:0007608 61 49 0,000 0,23460882 0,25179668 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,23460882 0,25167924 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,23460882 0,25156191 ! RNA elongation GO:0006354 62 49 0,000 0,23460882 0,25144468 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,23460882 0,25132757 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,23460882 0,25121056 ! regulation of actin filament length GO:0030832 72 50 0,000 0,23877977 0,25555769 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,23877977 0,25543883 ! membrane fusion GO:0006944 80 50 0,000 0,23877977 0,25532007 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,23877977 0,25520143 ! proton transport GO:0015992 75 50 0,000 0,23877977 0,2550829 ! positive regulation of secretion GO:0051047 71 51 0,000 0,24292823 0,25939412 ! hydrogen transport GO:0006818 77 51 0,000 0,24292823 0,25927375 ! muscle fiber development GO:0048747 74 51 0,000 0,24292823 0,25915349 ! adult behavior GO:0030534 80 51 0,000 0,24292823 0,25903335 ! transition metal ion transport GO:0000041 74 52 0,000 0,24705432 0,2633109 ! regulation of cellular component size GO:0032535 74 52 0,000 0,24705432 0,26318894 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,24705432 0,2630671 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,24705432 0,26294536 ! establishment of organelle localization GO:0051656 85 52 0,000 0,24705432 0,26282374 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,25115815 0,267066 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,25115815 0,26694258 ! single fertilization GO:0007338 59 53 0,000 0,25115815 0,26681928 ! cell projection assembly GO:0030031 76 53 0,000 0,25115815 0,2666961 ! amino acid transport GO:0006865 84 54 0,000 0,25523985 0,27090524 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,25523985 0,27078029 ! glucose catabolic process GO:0006007 66 54 0,000 0,25523985 0,27065545 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,25523985 0,27053072 ! detection of external stimulus GO:0009581 66 54 0,000 0,25523985 0,27040611 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,25523985 0,27028161 ! exocytosis GO:0006887 74 55 0,000 0,25929954 0,27445418 ! mesoderm development GO:0007498 76 55 0,000 0,25929954 0,27432794 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,25929954 0,27420181 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,25929954 0,2740758 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,26333733 0,27821583 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,26333733 0,27808809 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,26333733 0,27796047 ! carbohydrate transport GO:0008643 74 57 0,000 0,26735334 0,28207003 ! chromosome segregation GO:0007059 83 57 0,000 0,26735334 0,2819407 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,26735334 0,28181149 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,26735334 0,2816824 ! camera-type eye development GO:0043010 88 57 0,000 0,26735334 0,28155342 ! developmental maturation GO:0021700 75 57 0,000 0,26735334 0,28142456 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,27134768 0,28549847 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,27134768 0,28536793 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,27532047 0,28941366 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,27532047 0,28928145 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,27927183 0,29329919 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,27927183 0,29316532 ! regulation of heart contraction GO:0008016 91 60 0,000 0,27927183 0,29303158 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,27927183 0,29289796 ! fertilization GO:0009566 68 60 0,000 0,27927183 0,29276446 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,28320188 0,29674912 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,28320188 0,29661399 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,28320188 0,29647898 ! extracellular matrix organization GO:0030198 103 61 0,000 0,28320188 0,29634409 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,28320188 0,29620933 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,28711071 0,3001612 ! neurotransmitter transport GO:0006836 81 62 0,000 0,28711071 0,30002482 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,28711071 0,29988857 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,28711071 0,29975244 ! organelle localization GO:0051640 96 62 0,000 0,28711071 0,29961644 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,29486522 0,30756916 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,29486522 0,30742974 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,29486522 0,30729044 ! hexose catabolic process GO:0019320 82 64 0,000 0,29486522 0,30715127 ! adaptive immune response GO:0002250 94 64 0,000 0,29486522 0,30701222 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! defense response to bacterium GO:0042742 73 65 0,000 0,29871111 0,31087582 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,29871111 0,31073521 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,29871111 0,31059474 ! activation of immune response GO:0002253 83 65 0,000 0,29871111 0,31045439 ! protein oligomerization GO:0051259 100 65 0,000 0,29871111 0,31031416 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,30253625 0,31414599 ! antigen processing and presentation GO:0019882 96 66 0,000 0,30253625 0,31400423 ! axon guidance GO:0007411 99 66 0,000 0,30253625 0,3138626 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,30253625 0,31372109 ! regulation of immune effector process GO:0002697 101 66 0,000 0,30253625 0,31357971 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,30634074 0,31738005 ! acute inflammatory response GO:0002526 92 68 0,000 0,3101247 0,3211557 ! learning or memory GO:0007611 123 68 0,000 0,3101247 0,32101117 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,3101247 0,32086676 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,3101247 0,32072249 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,3101247 0,32057834 ! inorganic anion transport GO:0015698 93 68 0,000 0,3101247 0,32043433 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,31388824 0,32417734 ! eye development GO:0001654 111 70 0,000 0,31763145 0,32789602 ! amine transport GO:0015837 101 70 0,000 0,31763145 0,32774892 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,31763145 0,32760195 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,32135446 0,33129326 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,32135446 0,33114483 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,32135446 0,33099653 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,32135446 0,33084837 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,32505737 0,33451094 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,32505737 0,33436133 ! regulation of blood pressure GO:0008217 107 73 0,000 0,32874028 0,3379985 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,32874028 0,33784747 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,33240331 0,34145941 ! digestion GO:0007586 97 74 0,000 0,33240331 0,34130697 ! protein import into nucleus GO:0006606 118 74 0,000 0,33240331 0,34115467 ! nuclear import GO:0051170 121 75 0,000 0,33604656 0,34474 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,33604656 0,34458631 ! tRNA metabolic process GO:0006399 95 76 0,000 0,33967014 0,34814675 ! response to unfolded protein GO:0006986 99 76 0,000 0,33967014 0,34799168 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,33967014 0,34783674 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,34327414 0,35137095 ! protein ubiquitination GO:0016567 125 77 0,000 0,34327414 0,35121465 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,34327414 0,35105848 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,34327414 0,35090246 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,34327414 0,35074657 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,34685868 0,35425176 ! cellular respiration GO:0045333 107 79 0,000 0,35042387 0,35773408 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,35042387 0,35757537 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,35042387 0,3574168 ! chromatin assembly GO:0031497 102 80 0,000 0,35396979 0,36087346 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,35396979 0,36071357 ! protein localization in nucleus GO:0034504 133 80 0,000 0,35396979 0,36055382 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,35396979 0,36039421 ! mRNA transport GO:0051028 121 81 0,000 0,35749656 0,36382393 ! regulation of neurological system process GO:0031644 122 81 0,000 0,35749656 0,36366302 ! vitamin metabolic process GO:0006766 103 81 0,000 0,35749656 0,36350225 ! detection of stimulus GO:0051606 108 82 0,000 0,36100428 0,36690669 ! regulation of defense response GO:0031347 117 84 0,000 0,36796297 0,37381397 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,36796297 0,37364893 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,36796297 0,37348404 ! sterol metabolic process GO:0016125 120 84 0,000 0,36796297 0,37331929 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,37141415 0,37665456 ! rRNA metabolic process GO:0016072 107 85 0,000 0,37141415 0,37648856 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,37141415 0,3763227 ! nucleosome organization GO:0034728 114 87 0,000 0,37826065 0,38309093 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,37826065 0,38292231 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,37826065 0,38275385 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,38165618 0,38601988 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,38165618 0,3858502 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,38165618 0,38568067 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,38165618 0,38551129 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,38503336 0,38875186 ! regulation of T cell activation GO:0050863 128 89 0,000 0,38503336 0,38858128 ! hormone metabolic process GO:0042445 121 90 0,000 0,38839229 0,39179924 ! RNA localization GO:0006403 135 91 0,000 0,39173306 0,39499607 ! ATP metabolic process GO:0046034 137 91 0,000 0,39173306 0,39482298 ! positive regulation of immune response GO:0050778 121 92 0,000 0,39505578 0,3979975 ! DNA recombination GO:0006310 146 92 0,000 0,39505578 0,39782324 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,39836053 0,40097559 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,39836053 0,40080019 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,39836053 0,40062493 ! electron transport chain GO:0022900 123 94 0,000 0,40164742 0,40375397 ! carboxylic acid transport GO:0046942 147 95 0,000 0,40491655 0,40686241 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,40816799 0,40995039 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,40816799 0,40977145 ! protein maturation GO:0051604 129 96 0,000 0,40816799 0,40959266 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,41140186 0,41265778 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,41781724 0,41891005 ! extracellular structure organization GO:0043062 156 99 0,000 0,41781724 0,41872751 ! protein import GO:0017038 156 99 0,000 0,41781724 0,41854514 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,42099893 0,42154878 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,42099893 0,42136533 ! divalent metal ion transport GO:0070838 171 100 0,000 0,42099893 0,42118205 ! protein localization in organelle GO:0033365 161 100 0,000 0,42099893 0,42099893