pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1218-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! neutrophil homeostasis GO:0001780 10 6 4,000 9,309E-12 2,24E-08 ! pericardium development GO:0060039 14 7 4,000 3,247E-11 3,906E-08 ! myeloid cell homeostasis GO:0002262 13 8 4,000 8,627E-11 6,919E-08 ! leukocyte homeostasis GO:0001776 44 24 5,000 8,347E-10 5,021E-07 ! embryonic hindlimb morphogenesis GO:0035116 33 15 4,000 4,513E-09 2,172E-06 ! embryonic forelimb morphogenesis GO:0035115 28 16 4,000 6,541E-09 2,623E-06 ! auditory receptor cell differentiation GO:0042491 32 16 4,000 6,541E-09 2,248E-06 ! post-embryonic development GO:0009791 69 33 5,000 6,648E-09 1,999E-06 ! forelimb morphogenesis GO:0035136 32 19 4,000 1,723E-08 4,606E-06 ! inner ear receptor cell differentiation GO:0060113 37 20 4,000 2,289E-08 5,507E-06 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 2,994E-08 6,548E-06 ! hindlimb morphogenesis GO:0035137 43 21 4,000 2,994E-08 6,002E-06 ! mechanoreceptor differentiation GO:0042490 40 22 4,000 3,861E-08 7,145E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 1,997E-07 3,432E-05 ! ear development GO:0043583 103 62 5,000 3,323E-07 5,33E-05 ! lung development GO:0030324 144 67 5,000 5,298E-07 7,966E-05 ! homeostasis of number of cells GO:0048872 114 67 5,000 5,298E-07 7,498E-05 ! respiratory tube development GO:0030323 150 70 5,000 6,885E-07 9,203E-05 ! respiratory system development GO:0060541 153 72 5,000 8,146E-07 1,031E-04 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 8,365E-07 1,006E-04 ! response to hypoxia GO:0001666 171 81 5,000 1,638E-06 1,877E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 1,846E-06 2,019E-04 ! response to oxygen levels GO:0070482 176 83 5,000 1,891E-06 1,978E-04 ! inner ear development GO:0048839 79 50 4,000 2,813E-06 2,82E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 5,895E-06 5,674E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 6,936E-06 6,419E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 9,877E-06 8,802E-04 ! embryonic limb morphogenesis GO:0030326 125 65 4,000 1,04E-05 8,936E-04 GO:0035113|embryonic appendage morphogenesis, ! appendage morphogenesis GO:0035107 135 70 4,000 1,497E-05 1,242E-03 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 4,000 1,605E-05 1,287E-03 GO:0060173|limb development, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 2,000 1,799E-05 1,396E-03 ! negative regulation of mitotic cell cycle GO:0045930 33 13 2,000 2,331E-05 1,753E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 4,521E-05 3,296E-03 ! defense response to virus GO:0051607 37 16 2,000 4,521E-05 3,199E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 5,472E-05 3,761E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 6,562E-05 4,386E-03 ! forebrain development GO:0030900 188 95 4,000 6,562E-05 4,267E-03 ! regulation of protein localization GO:0032880 176 97 4,000 7,248E-05 4,589E-03 ! interphase GO:0051325 213 98 4,000 7,611E-05 4,695E-03 ! Golgi vesicle transport GO:0048193 207 99 4,000 7,987E-05 4,804E-03 ! response to UV GO:0009411 104 53 3,000 9E-05 5,281E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 9,085E-05 5,204E-03 ! regulation of protein catabolic process GO:0042176 116 55 3,000 1,041E-04 5,825E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,219E-04 6,667E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 1,561E-04 8,345E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,919E-04 0,01003626 ! endochondral ossification GO:0001958 16 5 1,000 1,919E-04 9,823E-03 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,919E-04 9,618E-03 ! valine metabolic process GO:0006573 10 5 1,000 1,919E-04 9,422E-03 ! muscle cell migration GO:0014812 8 5 1,000 1,919E-04 9,233E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,919E-04 9,052E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 1,919E-04 8,878E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 1,919E-04 8,711E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 1,919E-04 8,549E-03 ! B cell homeostasis GO:0001782 13 5 1,000 1,919E-04 8,394E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 1,919E-04 8,244E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,919E-04 8,099E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 2,032E-04 8,43E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,032E-04 8,287E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 2,246E-04 9,006E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 2,246E-04 8,859E-03 ! mitochondrial membrane organization GO:0007006 57 27 2,000 2,279E-04 8,843E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 2,516E-04 9,609E-03 ! urogenital system development GO:0001655 137 69 3,000 2,516E-04 9,458E-03 ! male meiosis GO:0007140 7 6 1,000 2,87E-04 0,01062301 ! neuron apoptosis GO:0051402 9 6 1,000 2,87E-04 0,01046205 ! neural nucleus development GO:0048857 14 6 1,000 2,87E-04 0,0103059 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 2,87E-04 0,01015435 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 3,133E-04 0,0109231 ! regulation of catabolic process GO:0009894 161 76 3,000 3,646E-04 0,01253146 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 3,802E-04 0,01288517 ! prostate gland development GO:0030850 13 7 1,000 4,006E-04 0,01338742 ! SMAD protein complex assembly GO:0007183 12 7 1,000 4,006E-04 0,01320403 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,006E-04 0,0130256 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 4,006E-04 0,01285192 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 4,006E-04 0,01268282 GO:0021940|positive regulation of granule cell precursor proliferation, ! organ growth GO:0035265 15 7 1,000 4,006E-04 0,01251811 ! fibrinolysis GO:0042730 10 7 1,000 4,006E-04 0,01235762 ! B cell lineage commitment GO:0002326 21 7 1,000 4,006E-04 0,01220119 ! T cell lineage commitment GO:0002360 16 7 1,000 4,006E-04 0,01204868 ! peptidyl-threonine modification GO:0018210 25 7 1,000 4,006E-04 0,01189993 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 4,006E-04 0,01175481 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 4,226E-04 0,01225138 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 4,648E-04 0,01331373 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 3,000 4,87E-04 0,01378486 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 5,326E-04 0,01490083 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 5,326E-04 0,01472956 ! succinate metabolic process GO:0006105 14 8 1,000 5,326E-04 0,01456218 ! pigment granule organization GO:0048753 16 8 1,000 5,326E-04 0,01439856 ! regulation of pigmentation during development GO:0048070 24 8 1,000 5,326E-04 0,01423857 ! melanin metabolic process GO:0006582 15 8 1,000 5,326E-04 0,0140821 ! response to UV-B GO:0010224 16 8 1,000 5,326E-04 0,01392904 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,326E-04 0,01377926 ! negative regulation of growth GO:0045926 155 84 3,000 5,336E-04 0,01365778 ! regulation of proteolysis GO:0030162 72 36 2,000 5,403E-04 0,01368488 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 5,403E-04 0,01354233 ! regulation of protein stability GO:0031647 73 37 2,000 5,861E-04 0,01453839 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 5,861E-04 0,01439004 ! regulation of protein transport GO:0051223 154 87 3,000 6,093E-04 0,01480824 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 3,000 6,362E-04 0,01530615 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 6,828E-04 0,01626572 GO:0010469|regulation of receptor activity, ! T cell selection GO:0045058 23 9 1,000 6,828E-04 0,01610625 ! phosphagen metabolic process GO:0006599 12 9 1,000 6,828E-04 0,01594988 GO:0006600|creatine metabolic process, ! receptor clustering GO:0043113 18 9 1,000 6,828E-04 0,01579652 ! behavioral fear response GO:0001662 22 9 1,000 6,828E-04 0,01564608 GO:0002209|behavioral defense response, ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 6,828E-04 0,01549847 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 6,828E-04 0,01535363 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 7,831E-04 0,01744619 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 8,51E-04 0,01878538 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 8,51E-04 0,0186146 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 8,51E-04 0,0184469 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 8,51E-04 0,0182822 ! polyamine biosynthetic process GO:0006596 12 10 1,000 8,51E-04 0,01812041 ! B cell proliferation GO:0042100 18 10 1,000 8,51E-04 0,01796146 ! alpha-beta T cell activation GO:0046631 23 10 1,000 8,51E-04 0,01780527 ! protein sumoylation GO:0016925 15 10 1,000 8,51E-04 0,01765178 ! oocyte development GO:0048599 17 10 1,000 8,51E-04 0,01750091 ! response to nicotine GO:0035094 20 10 1,000 8,51E-04 0,0173526 ! localization within membrane GO:0051668 20 10 1,000 8,51E-04 0,01720678 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 8,522E-04 0,01708578 ! cell cycle arrest GO:0007050 213 100 3,000 1,027E-03 0,02042197 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,037E-03 0,02045403 ! blood vessel remodeling GO:0001974 29 11 1,000 1,037E-03 0,02028774 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,037E-03 0,02012413 ! chondrocyte differentiation GO:0002062 24 11 1,000 1,037E-03 0,01996314 ! negative regulation of ossification GO:0030279 26 11 1,000 1,037E-03 0,0198047 ! oocyte differentiation GO:0009994 18 11 1,000 1,037E-03 0,01964876 ! thymus development GO:0048538 27 11 1,000 1,037E-03 0,01949525 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 1,043E-03 0,01945694 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,043E-03 0,01930727 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,112E-03 0,0204308 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,112E-03 0,02027602 ! negative regulation of cell migration GO:0030336 115 46 2,000 1,112E-03 0,02012357 ! response to insulin stimulus GO:0032868 95 46 2,000 1,112E-03 0,01997339 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,112E-03 0,01982544 ! positive regulation of DNA binding GO:0043388 73 47 2,000 1,184E-03 0,02095397 ! virus-host interaction GO:0019048 29 12 1,000 1,241E-03 0,02179426 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,241E-03 0,02163633 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,241E-03 0,02148067 ! polyamine metabolic process GO:0006595 17 12 1,000 1,241E-03 0,02132724 ! focal adhesion formation GO:0048041 35 12 1,000 1,241E-03 0,02117598 ! fear response GO:0042596 26 12 1,000 1,241E-03 0,02102685 ! histone acetylation GO:0016573 26 12 1,000 1,241E-03 0,02087981 ! gland morphogenesis GO:0022612 29 12 1,000 1,241E-03 0,02073481 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,241E-03 0,02059181 ! T cell homeostasis GO:0043029 25 12 1,000 1,241E-03 0,02045077 ! spleen development GO:0048536 22 12 1,000 1,241E-03 0,02031165 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,241E-03 0,02017441 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,259E-03 0,02033533 ! mitochondrial transport GO:0006839 82 48 2,000 1,259E-03 0,02019976 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,462E-03 0,02330126 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,462E-03 0,02314796 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,462E-03 0,02299666 ! positive regulation of binding GO:0051099 78 51 2,000 1,502E-03 0,0234622 ! positive regulation of growth GO:0045927 90 52 2,000 1,589E-03 0,02465868 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,589E-03 0,02450061 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,701E-03 0,02607035 ! hair follicle morphogenesis GO:0031069 26 14 1,000 1,701E-03 0,02590535 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 1,701E-03 0,02574242 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 1,701E-03 0,02558153 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 1,701E-03 0,02542264 ! response to gamma radiation GO:0010332 28 14 1,000 1,701E-03 0,02526571 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,701E-03 0,02511071 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 1,868E-03 0,02740075 ! negative regulation of cell motion GO:0051271 134 55 2,000 1,868E-03 0,02723469 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,957E-03 0,0283681 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,957E-03 0,02819823 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,957E-03 0,02803038 ! positive regulation of cell migration GO:0030335 126 57 2,000 2,07E-03 0,02946625 ! regulation of intracellular transport GO:0032386 101 57 2,000 2,07E-03 0,02929292 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 2,23E-03 0,03138184 ! activation of MAPKK activity GO:0000186 35 16 1,000 2,23E-03 0,03119939 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 2,23E-03 0,03101905 ! kidney development GO:0001822 122 60 2,000 2,397E-03 0,03315036 ! metencephalon development GO:0022037 30 17 1,000 2,52E-03 0,03465285 ! signal complex assembly GO:0007172 41 17 1,000 2,52E-03 0,03445595 ! regulation of viral genome replication GO:0045069 28 17 1,000 2,52E-03 0,03426129 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,52E-03 0,03406881 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 2,52E-03 0,03387848 ! regulation of protein binding GO:0043393 33 17 1,000 2,52E-03 0,03369027 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,52E-03 0,03350413 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 2,52E-03 0,03332004 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 2,52E-03 0,03313797 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 2,52E-03 0,03295787 ! regulation of mitosis GO:0007088 105 63 2,000 2,755E-03 0,03583598 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,755E-03 0,03564332 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,827E-03 0,03637752 ! epidermis morphogenesis GO:0048730 40 18 1,000 2,827E-03 0,03618402 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,827E-03 0,03599257 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,827E-03 0,03580313 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 2,882E-03 0,03630078 ! positive regulation of cell motion GO:0051272 146 64 2,000 2,882E-03 0,03611172 ! actin filament organization GO:0007015 148 66 2,000 3,145E-03 0,03920435 ! lipid phosphorylation GO:0046834 35 19 1,000 3,151E-03 0,03907718 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 3,151E-03 0,03887678 ! cellular pigmentation GO:0033059 36 19 1,000 3,151E-03 0,03867843 ! activation of MAPK activity GO:0000187 115 67 2,000 3,282E-03 0,04008013 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 3,422E-03 0,04158484 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 3,491E-03 0,04220611 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,491E-03 0,04199508 ! response to alkaloid GO:0043279 38 20 1,000 3,491E-03 0,04178615 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 3,491E-03 0,04157929 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 3,491E-03 0,04137447 ! peptidyl-serine modification GO:0018209 43 20 1,000 3,491E-03 0,04117165 ! negative regulation of translation GO:0017148 29 20 1,000 3,491E-03 0,04097081 ! negative regulation of coagulation GO:0050819 29 20 1,000 3,491E-03 0,04077193 ! ovarian follicle development GO:0001541 35 21 1,000 3,847E-03 0,04471675 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 3,847E-03 0,04450177 ! cell aging GO:0007569 44 21 1,000 3,847E-03 0,04428884 ! oogenesis GO:0048477 36 21 1,000 3,847E-03 0,04407794 ! response to cytokine stimulus GO:0034097 63 21 1,000 3,847E-03 0,04386904 ! gut development GO:0048565 39 21 1,000 3,847E-03 0,04366211 ! reproductive structure development GO:0048608 113 71 2,000 3,866E-03 0,04366445 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 4,22E-03 0,04744237 ! regeneration GO:0031099 41 22 1,000 4,22E-03 0,04722171 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,22E-03 0,04700309 ! apoptotic nuclear changes GO:0030262 32 22 1,000 4,22E-03 0,04678649 ! ureteric bud development GO:0001657 43 22 1,000 4,22E-03 0,04657187 ! renal system process GO:0003014 41 22 1,000 4,22E-03 0,04635922 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 4,22E-03 0,04614849 ! sarcomere organization GO:0045214 30 22 1,000 4,22E-03 0,04593968 ! positive regulation of B cell activation GO:0050871 38 22 1,000 4,22E-03 0,04573274 ! protein stabilization GO:0050821 39 22 1,000 4,22E-03 0,04552766 ! regulation of transcription factor activity GO:0051090 126 74 2,000 4,342E-03 0,04664159 GO:0090046|regulation of transcription regulator activity, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 4,608E-03 0,04927805 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 4,608E-03 0,04906001 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 4,608E-03 0,04884389 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,608E-03 0,04862966 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,608E-03 0,0484173 ! regulation of viral reproduction GO:0050792 38 23 1,000 4,608E-03 0,04820679 ! negative regulation of catabolic process GO:0009895 50 23 1,000 4,608E-03 0,0479981 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 5,013E-03 0,05198576 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 5,013E-03 0,05176265 ! multicellular organismal response to stress GO:0033555 49 24 1,000 5,013E-03 0,05154144 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 5,013E-03 0,05132211 ! lymphocyte proliferation GO:0046651 48 24 1,000 5,013E-03 0,05110465 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 5,013E-03 0,05088902 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 5,013E-03 0,0506752 ! activation of protein kinase activity GO:0032147 147 79 2,000 5,213E-03 0,05248172 ! response to metal ion GO:0010038 140 80 2,000 5,399E-03 0,05412609 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 5,433E-03 0,05423951 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,433E-03 0,05401538 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 5,433E-03 0,05379309 ! receptor metabolic process GO:0043112 46 25 1,000 5,433E-03 0,05357263 ! osteoblast differentiation GO:0001649 60 25 1,000 5,433E-03 0,05335396 ! interaction with host GO:0051701 62 25 1,000 5,433E-03 0,05313708 ! somitogenesis GO:0001756 43 25 1,000 5,433E-03 0,05292195 ! regulation of blood coagulation GO:0030193 40 25 1,000 5,433E-03 0,05270855 ! molting cycle process GO:0022404 50 26 1,000 5,869E-03 0,05670798 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 5,869E-03 0,05648115 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,869E-03 0,05625612 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 5,869E-03 0,05603288 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 52 26 1,000 5,869E-03 0,05581141 GO:0032943|mononuclear cell proliferation, ! negative regulation of transport GO:0051051 153 84 2,000 6,182E-03 0,05855952 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 6,32E-03 0,05963156 ! protein amino acid acylation GO:0043543 55 27 1,000 6,32E-03 0,05939862 ! male gonad development GO:0008584 44 27 1,000 6,32E-03 0,0591675 ! response to toxin GO:0009636 47 27 1,000 6,32E-03 0,05893817 ! response to inorganic substance GO:0010035 153 86 2,000 6,598E-03 0,06128942 ! tube morphogenesis GO:0035239 176 86 2,000 6,598E-03 0,06105369 ! mitochondrion organization GO:0007005 148 86 2,000 6,598E-03 0,06081977 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 6,787E-03 0,06232313 ! gland development GO:0048732 206 88 2,000 7,029E-03 0,0643077 ! response to organic cyclic substance GO:0014070 55 29 1,000 7,268E-03 0,0662416 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 7,268E-03 0,06599163 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 7,268E-03 0,06574354 ! tissue homeostasis GO:0001894 48 29 1,000 7,268E-03 0,06549731 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 1,000 7,268E-03 0,06525292 ! ossification GO:0001503 188 90 2,000 7,478E-03 0,06688245 ! regulation of cell cycle process GO:0010564 149 90 2,000 7,478E-03 0,06663474 ! sex differentiation GO:0007548 145 90 2,000 7,478E-03 0,06638886 ! bone development GO:0060348 189 91 2,000 7,708E-03 0,06818207 ! cell junction assembly GO:0034329 78 30 1,000 7,765E-03 0,06843617 ! myofibril assembly GO:0030239 47 30 1,000 7,765E-03 0,0681864 GO:0055002|striated muscle cell development, ! regulation of B cell activation GO:0050864 50 30 1,000 7,765E-03 0,06793845 ! response to heat GO:0009408 50 30 1,000 7,765E-03 0,0676923 ! regulation of membrane potential GO:0042391 164 93 2,000 8,181E-03 0,07106083 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 8,181E-03 0,07080521 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 8,277E-03 0,07137706 ! ovulation cycle process GO:0022602 49 31 1,000 8,277E-03 0,07112214 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 8,277E-03 0,07086903 GO:0043433|negative regulation of transcription factor activity, ! response to hydrogen peroxide GO:0042542 50 32 1,000 8,803E-03 0,0751093 ! metanephros development GO:0001656 74 32 1,000 8,803E-03 0,07484389 ! response to ionizing radiation GO:0010212 65 32 1,000 8,803E-03 0,07458036 ! muscle cell development GO:0055001 49 32 1,000 8,803E-03 0,07431867 ! ovulation cycle GO:0042698 51 32 1,000 8,803E-03 0,07405882 ! hindbrain development GO:0030902 61 32 1,000 8,803E-03 0,07380077 ! negative regulation of protein transport GO:0051224 69 33 1,000 9,344E-03 0,07806462 ! response to virus GO:0009615 160 98 2,000 9,438E-03 0,07856983 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 9,9E-03 0,08213529 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 9,9E-03 0,08185304 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 9,9E-03 0,08157272 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 9,9E-03 0,08129432 ! regulation of muscle development GO:0048634 70 35 1,000 0,01046981 0,08568152 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01046981 0,08539107 ! negative regulation of secretion GO:0051048 63 35 1,000 0,01046981 0,08510259 ! female gonad development GO:0008585 58 35 1,000 0,01046981 0,08481605 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01046981 0,08453143 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,0110539 0,08894876 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,0110539 0,08865226 ! cell junction organization GO:0034330 86 36 1,000 0,0110539 0,08835774 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,0110539 0,08806516 ! positive regulation of cell development GO:0010720 80 36 1,000 0,0110539 0,08777452 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01165206 0,09221989 ! actomyosin structure organization GO:0031032 62 37 1,000 0,01165206 0,09191753 ! tissue remodeling GO:0048771 76 37 1,000 0,01165206 0,09161715 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01165206 0,09131872 ! pigment metabolic process GO:0042440 80 37 1,000 0,01165206 0,09102223 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01226415 0,09549369 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01226415 0,09518565 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01226415 0,09487959 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01289005 0,09940215 ! segmentation GO:0035282 67 39 1,000 0,01289005 0,09908457 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01352963 0,10366971 ! negative regulation of binding GO:0051100 72 40 1,000 0,01352963 0,1033406 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01352963 0,10301357 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01352963 0,10268861 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,01352963 0,10236569 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,01418275 0,10697081 ! T cell differentiation GO:0030217 81 41 1,000 0,01418275 0,10663653 ! female gamete generation GO:0007292 61 41 1,000 0,01418275 0,10630433 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01484928 0,11095453 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01484928 0,11061102 ! regulation of protein secretion GO:0050708 71 42 1,000 0,01484928 0,11026962 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01552909 0,11496303 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01552909 0,11461039 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01622205 0,1193586 ! male sex differentiation GO:0046661 76 44 1,000 0,01622205 0,11899471 ! B cell differentiation GO:0030183 107 44 1,000 0,01622205 0,11863302 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01622205 0,11827353 ! developmental growth GO:0048589 82 44 1,000 0,01622205 0,1179162 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01622205 0,11756104 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01692805 0,12230896 ! cell growth GO:0016049 84 45 1,000 0,01692805 0,12194276 ! pigmentation GO:0043473 100 46 1,000 0,01764694 0,12674191 ! response to calcium ion GO:0051592 81 47 1,000 0,01837861 0,13160396 ! endosome transport GO:0016197 108 47 1,000 0,01837861 0,13121344 ! cellular component disassembly GO:0022411 86 48 1,000 0,01912292 0,13612354 ! activation of caspase activity GO:0006919 84 48 1,000 0,01912292 0,13572199 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01912292 0,13532281 ! response to temperature stimulus GO:0009266 76 49 1,000 0,01987977 0,14026603 ! regulation of ossification GO:0030278 117 50 1,000 0,02064901 0,14526758 ! histone modification GO:0016570 91 50 1,000 0,02064901 0,14484406 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,02064901 0,144423 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,02143053 0,14945464 ! chromatin remodeling GO:0006338 109 51 1,000 0,02143053 0,14902269 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,02143053 0,14859323 ! vesicle organization GO:0016050 107 51 1,000 0,02143053 0,14816624 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,02143053 0,1477417 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,02143053 0,14731958 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02188783 0,15003454 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02188783 0,14960831 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02188783 0,14918449 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02188783 0,14876306 ! neuron fate determination GO:0048664 7 5 0,000 0,02188783 0,14834401 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02188783 0,14792732 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02188783 0,14751295 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02188783 0,14710091 ! polyol transport GO:0015791 12 5 0,000 0,02188783 0,14669115 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02188783 0,14628368 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02188783 0,14587846 ! response to superoxide GO:0000303 10 5 0,000 0,02188783 0,14547548 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02188783 0,14507472 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02188783 0,14467617 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02188783 0,14427979 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02188783 0,14388559 ! female meiosis GO:0007143 7 5 0,000 0,02188783 0,14349353 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02188783 0,1431036 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02188783 0,14271578 ! cobalt ion transport GO:0006824 11 5 0,000 0,02188783 0,14233007 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02188783 0,14194643 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02188783 0,14156485 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02188783 0,14118532 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02188783 0,14080782 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02188783 0,14043233 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02188783 0,14005884 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02188783 0,13968733 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02188783 0,13931779 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02188783 0,1389502 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02188783 0,13858454 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02188783 0,1382208 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02188783 0,13785896 ! negative chemotaxis GO:0050919 14 5 0,000 0,02188783 0,13749902 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02188783 0,13714095 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02188783 0,13678474 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02188783 0,13643037 ! behavioral response to pain GO:0048266 9 5 0,000 0,02188783 0,13607784 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02188783 0,13572712 ! Notch receptor processing GO:0007220 8 5 0,000 0,02188783 0,13537821 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02188783 0,13503109 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02188783 0,13468574 ! micturition GO:0060073 9 5 0,000 0,02188783 0,13434215 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02188783 0,13400032 ! copulation GO:0007620 9 5 0,000 0,02188783 0,13366021 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02188783 0,13332183 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02188783 0,13298516 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02188783 0,13265019 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02188783 0,1323169 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02188783 0,13198527 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02188783 0,13165531 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02188783 0,13132699 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02188783 0,13100031 ! grooming behavior GO:0007625 6 5 0,000 0,02188783 0,13067525 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02188783 0,13035179 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02188783 0,13002994 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02188783 0,12970967 ! response to protozoan GO:0001562 10 5 0,000 0,02188783 0,12939097 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02188783 0,12907383 ! lymph vessel development GO:0001945 10 5 0,000 0,02188783 0,12875825 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02188783 0,12844421 ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02188783 0,12813169 ! parathyroid gland development GO:0060017 13 5 0,000 0,02188783 0,12782069 ! anagen GO:0042640 6 5 0,000 0,02188783 0,1275112 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02188783 0,1272032 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02188783 0,12689669 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02188783 0,12659165 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02188783 0,12628807 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02188783 0,12598594 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02188783 0,12568526 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02188783 0,12538601 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02188783 0,12508818 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02188783 0,12479176 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02188783 0,12449675 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02188783 0,12420312 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02188783 0,12391088 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02188783 0,12362001 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02188783 0,1233305 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02188783 0,12304235 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02188783 0,12275553 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02188783 0,12247006 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02188783 0,1221859 ! histidine catabolic process GO:0006548 6 5 0,000 0,02188783 0,12190307 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02188783 0,12162153 ! microvillus organization GO:0032528 7 5 0,000 0,02188783 0,1213413 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02188783 0,12106235 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02188783 0,12078469 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02188783 0,12050829 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02188783 0,12023316 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02188783 0,11995928 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02188783 0,11968665 ! polyol catabolic process GO:0046174 7 5 0,000 0,02188783 0,11941525 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02188783 0,11914508 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02188783 0,11887613 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02188783 0,11860839 ! mitochondrial fission GO:0000266 8 5 0,000 0,02188783 0,11834185 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02188783 0,11807651 ! mRNA transcription GO:0009299 9 5 0,000 0,02188783 0,11781236 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02188783 0,11754938 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02188783 0,11728758 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02188783 0,11702694 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02188783 0,11676746 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02188783 0,11650912 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02188783 0,11625193 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02188783 0,11599587 ! response to food GO:0032094 6 5 0,000 0,02188783 0,11574093 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02188783 0,11548711 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02188783 0,11523441 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02188783 0,1149828 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02188783 0,1147323 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02188783 0,11448288 ! forebrain neuron development GO:0021884 13 5 0,000 0,02188783 0,11423454 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02188783 0,11398728 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02188783 0,11374109 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02188783 0,11349596 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02188783 0,11325188 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02188783 0,11300885 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02188783 0,11276686 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02188783 0,11252591 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02188783 0,11228598 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02188783 0,11204707 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02188783 0,11180918 ! basic amino acid transport GO:0015802 11 5 0,000 0,02188783 0,1115723 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02188783 0,11133642 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02188783 0,11110153 ! depyrimidination GO:0045008 10 5 0,000 0,02188783 0,11086763 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02188783 0,11063472 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02188783 0,11040278 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02188783 0,11017181 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02188783 0,1099418 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02188783 0,10971276 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02188783 0,10948467 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02188783 0,10925752 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02188783 0,10903131 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02188783 0,10880604 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02188783 0,1085817 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02188783 0,10835828 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02188783 0,10813578 ! response to arsenic GO:0046685 10 5 0,000 0,02188783 0,10791419 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02188783 0,10769351 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02188783 0,10747372 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02188783 0,10725484 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02188783 0,10703684 ! response to cadmium ion GO:0046686 7 5 0,000 0,02188783 0,10681972 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02188783 0,10660349 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02188783 0,10638813 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02188783 0,10617364 ! decidualization GO:0046697 11 5 0,000 0,02188783 0,10596001 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02188783 0,10574724 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02188783 0,10553532 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02188783 0,10532425 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02188783 0,10511402 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02188783 0,10490463 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02188783 0,10469607 ! neural tube patterning GO:0021532 7 5 0,000 0,02188783 0,10448834 ! embryonic cleavage GO:0040016 6 5 0,000 0,02188783 0,10428143 ! peroxisome fission GO:0016559 5 5 0,000 0,02188783 0,10407534 ! histone demethylation GO:0016577 10 5 0,000 0,02188783 0,10387007 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02188783 0,1036656 ! mitotic recombination GO:0006312 9 5 0,000 0,02188783 0,10346193 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02188783 0,10325907 ! metaphase plate congression GO:0051310 7 5 0,000 0,02188783 0,10305699 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02188783 0,10285571 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02188783 0,10265521 ! enteric nervous system development GO:0048484 8 5 0,000 0,02188783 0,10245549 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02188783 0,10225655 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02188783 0,10205838 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02188783 0,10186098 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02188783 0,10166433 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02188783 0,10146845 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02188783 0,10127332 ! plasminogen activation GO:0031639 5 5 0,000 0,02188783 0,10107893 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02188783 0,1008853 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02188783 0,1006924 ! metaphase GO:0051323 8 5 0,000 0,02188783 0,10050024 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02188783 0,10030881 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02188783 0,10011811 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02188783 0,09992813 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02188783 0,09973887 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02188783 0,09955033 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02188783 0,0993625 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02188783 0,09917538 ! response to redox state GO:0051775 5 5 0,000 0,02188783 0,09898896 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02188783 0,09880324 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02188783 0,09861821 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02188783 0,09843388 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02188783 0,09825023 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02188783 0,09806727 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02188783 0,09788499 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02188783 0,09770338 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02188783 0,09752245 ! striatum development GO:0021756 9 5 0,000 0,02188783 0,09734219 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02188783 0,09716259 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02188783 0,09698365 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02188783 0,09680538 ! glial cell migration GO:0008347 11 5 0,000 0,02188783 0,09662775 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02188783 0,09645078 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02188783 0,09627445 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02188783 0,09609877 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02188783 0,09592372 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02188783 0,09574932 ! neuroprotection GO:0043526 6 5 0,000 0,02188783 0,09557554 ! neural plate development GO:0001840 8 5 0,000 0,02188783 0,0954024 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02188783 0,09522988 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02188783 0,09505799 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02188783 0,09488671 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02188783 0,09471605 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02188783 0,094546 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02188783 0,09437657 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02188783 0,09420774 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02188783 0,09403951 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02188783 0,09387188 ! spindle assembly GO:0051225 6 5 0,000 0,02188783 0,09370485 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02188783 0,09353841 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02188783 0,09337256 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02188783 0,0932073 ! drug metabolic process GO:0017144 6 5 0,000 0,02188783 0,09304262 ! stem cell division GO:0017145 11 5 0,000 0,02188783 0,09287853 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02188783 0,09271501 ! organ regeneration GO:0031100 7 5 0,000 0,02188783 0,09255206 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02188783 0,09238969 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02188783 0,09222789 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02188783 0,09206665 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02222421 0,0933184 ! cartilage development GO:0051216 90 52 1,000 0,02222421 0,09315582 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02302992 0,0963652 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02384755 0,09961321 GO:0010863|positive regulation of phospholipase C activity, ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,02384755 0,09944058 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,02467698 0,10272113 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02467698 0,10254372 ! aging GO:0007568 103 55 1,000 0,02467698 0,10236692 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02551809 0,10567387 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,026208 0,10834442 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,026208 0,10815858 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,026208 0,10797337 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,026208 0,1077888 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,026208 0,10760486 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,026208 0,10742155 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,026208 0,10723886 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,026208 0,10705679 ! sleep GO:0030431 13 6 0,000 0,026208 0,10687534 ! response to oxygen radical GO:0000305 11 6 0,000 0,026208 0,1066945 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,026208 0,10651427 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,026208 0,10633465 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,026208 0,10615564 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,026208 0,10597723 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,026208 0,10579941 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,026208 0,10562219 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,026208 0,10544557 ! forebrain regionalization GO:0021871 8 6 0,000 0,026208 0,10526953 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,026208 0,10509408 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,026208 0,10491922 ! response to zinc ion GO:0010043 9 6 0,000 0,026208 0,10474493 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,026208 0,10457123 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,026208 0,1043981 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,026208 0,10422554 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,026208 0,10405355 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,026208 0,10388213 ! malate metabolic process GO:0006108 11 6 0,000 0,026208 0,10371127 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,026208 0,10354097 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,026208 0,10337123 ! protein refolding GO:0042026 15 6 0,000 0,026208 0,10320205 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,026208 0,10303342 ! opsonization GO:0008228 8 6 0,000 0,026208 0,10286533 ! mating behavior GO:0007617 7 6 0,000 0,026208 0,1026978 ! neuron remodeling GO:0016322 15 6 0,000 0,026208 0,10253081 ! erythrocyte maturation GO:0043249 7 6 0,000 0,026208 0,10236437 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,026208 0,10219846 ! equilibrioception GO:0050957 14 6 0,000 0,026208 0,10203309 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,026208 0,10186826 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,026208 0,10170395 ! photoreceptor cell development GO:0042461 10 6 0,000 0,026208 0,10154018 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,026208 0,10137693 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,026208 0,10121421 ! response to interferon-gamma GO:0034341 15 6 0,000 0,026208 0,101052 ! toxin metabolic process GO:0009404 11 6 0,000 0,026208 0,10089032 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,026208 0,10072915 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,026208 0,1005685 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,026208 0,10040836 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,026208 0,10024873 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,026208 0,1000896 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,026208 0,09993098 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,026208 0,09977286 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,026208 0,09961525 ! thymic T cell selection GO:0045061 12 6 0,000 0,026208 0,09945812 ! protein lipoylation GO:0009249 10 6 0,000 0,026208 0,0993015 ! cysteine metabolic process GO:0006534 10 6 0,000 0,026208 0,09914536 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,026208 0,09898972 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,026208 0,09883456 ! glutamate catabolic process GO:0006538 10 6 0,000 0,026208 0,09867989 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,026208 0,0985257 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,026208 0,098372 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,026208 0,09821877 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,026208 0,09806602 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,026208 0,09791374 ! hyperosmotic response GO:0006972 9 6 0,000 0,026208 0,09776194 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,026208 0,0976106 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,026208 0,09745974 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,026208 0,09730934 ! urea metabolic process GO:0019627 7 6 0,000 0,026208 0,0971594 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,026208 0,09700992 ! neutrophil activation GO:0042119 8 6 0,000 0,026208 0,09686091 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,026208 0,09671235 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,026208 0,09656424 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,026208 0,09641659 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,026208 0,09626939 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,026208 0,09612264 ! nucleoside salvage GO:0043174 9 6 0,000 0,026208 0,09597633 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,026208 0,09583047 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,026208 0,09568505 ! T cell mediated immunity GO:0002456 16 6 0,000 0,026208 0,09554008 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,026208 0,09539554 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,026208 0,09525144 ! carnitine transport GO:0015879 10 6 0,000 0,026208 0,09510777 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,026208 0,09496453 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,026208 0,09482173 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,026208 0,09467935 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,026208 0,09453741 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,026208 0,09439588 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,026208 0,09425478 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,026208 0,0941141 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,026208 0,09397385 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,026208 0,093834 ! establishment of spindle localization GO:0051293 12 6 0,000 0,026208 0,09369458 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,026208 0,09355556 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,026208 0,09341696 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,026208 0,09327877 ! response to UV-C GO:0010225 11 6 0,000 0,026208 0,09314099 ! astrocyte development GO:0014002 15 6 0,000 0,026208 0,09300361 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,026208 0,09286664 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,026208 0,09273007 ! interaction with symbiont GO:0051702 13 6 0,000 0,026208 0,09259391 ! regulation of dendrite development GO:0050773 16 6 0,000 0,026208 0,09245814 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,026208 0,09232277 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,026208 0,09218779 ! response to copper ion GO:0046688 10 6 0,000 0,026208 0,09205321 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,026208 0,09191902 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,026208 0,09178523 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,026208 0,09165182 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,026208 0,0915188 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,026208 0,09138616 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,026208 0,09125391 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,026208 0,09112204 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,026208 0,09099055 ! hair follicle maturation GO:0048820 7 6 0,000 0,026208 0,09085944 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,026208 0,09072871 ! Schwann cell development GO:0014044 15 6 0,000 0,026208 0,09059835 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,026208 0,09046836 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,026208 0,09033875 ! subpallium development GO:0021544 10 6 0,000 0,026208 0,09020951 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,026208 0,09008064 ! histone ubiquitination GO:0016574 8 6 0,000 0,026208 0,08995214 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,026208 0,089824 ! maintenance of organ identity GO:0048496 9 6 0,000 0,026208 0,08969623 ! G2 phase GO:0051319 16 6 0,000 0,026208 0,08956882 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,026208 0,08944177 ! establishment of planar polarity GO:0001736 7 6 0,000 0,026208 0,08931509 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,026208 0,08918876 ! membrane to membrane docking GO:0022614 14 6 0,000 0,026208 0,08906278 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,026208 0,08893717 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,026208 0,0888119 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,026208 0,08868699 ! receptor internalization GO:0031623 10 6 0,000 0,026208 0,08856243 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,026208 0,08843822 GO:0031272|regulation of pseudopodium assembly, ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,026208 0,08831436 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,026208 0,08819084 ! protein deubiquitination GO:0016579 14 6 0,000 0,026208 0,08806767 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,026208 0,08794484 ! protein destabilization GO:0031648 9 6 0,000 0,026208 0,08782235 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,026208 0,08770021 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,026208 0,0875784 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,026208 0,08745694 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,026208 0,0873358 ! progesterone metabolic process GO:0042448 10 6 0,000 0,026208 0,08721501 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,026208 0,08709454 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,026208 0,08697441 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,026208 0,08685461 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,026208 0,08673514 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,026208 0,086616 ! determination of adult lifespan GO:0008340 15 6 0,000 0,026208 0,08649719 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,026208 0,0863787 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,026208 0,08626053 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,026208 0,08614269 ! catecholamine transport GO:0051937 9 6 0,000 0,026208 0,08602517 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,026208 0,08590797 ! sensory cilium assembly GO:0035058 10 6 0,000 0,026208 0,08579109 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,026208 0,08567452 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,026208 0,08555828 ! maternal placenta development GO:0001893 12 6 0,000 0,026208 0,08544234 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,026208 0,08532673 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,026208 0,08521142 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,026208 0,08509642 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,026208 0,08498174 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,026208 0,08486736 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,026208 0,08475329 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,026208 0,08463953 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,02637075 0,08505098 ! lipid modification GO:0030258 97 57 1,000 0,02637075 0,08493713 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02637075 0,08482357 ! maintenance of location GO:0051235 118 57 1,000 0,02637075 0,08471033 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,02723487 0,08736945 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02723487 0,08725311 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,0281103 0,08993802 ! DNA catabolic process GO:0006308 86 59 1,000 0,0281103 0,08981858 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02899696 0,09252875 ! tRNA transcription GO:0009304 14 7 0,000 0,03050923 0,09722544 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03050923 0,09709684 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03050923 0,09696857 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03050923 0,09684065 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03050923 0,09671306 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03050923 0,0965858 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03050923 0,09645888 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03050923 0,0963323 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03050923 0,09620604 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03050923 0,09608012 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03050923 0,09595452 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03050923 0,09582926 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03050923 0,09570431 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03050923 0,0955797 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03050923 0,09545541 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03050923 0,09533144 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03050923 0,09520779 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03050923 0,09508447 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03050923 0,09496146 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03050923 0,09483877 ! glycolipid transport GO:0046836 10 7 0,000 0,03050923 0,0947164 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03050923 0,09459434 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03050923 0,0944726 ! neuron adhesion GO:0007158 12 7 0,000 0,03050923 0,09435117 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03050923 0,09423005 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03050923 0,09410924 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03050923 0,09398874 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03050923 0,09386855 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03050923 0,09374867 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03050923 0,09362909 ! mRNA stabilization GO:0048255 18 7 0,000 0,03050923 0,09350982 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03050923 0,09339085 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03050923 0,09327218 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03050923 0,09315382 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03050923 0,09303575 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03050923 0,09291799 ! lipoprotein transport GO:0042953 14 7 0,000 0,03050923 0,09280052 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03050923 0,09268335 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03050923 0,09256647 ! rhythmic behavior GO:0007622 15 7 0,000 0,03050923 0,09244989 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03050923 0,0923336 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03050923 0,0922176 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03050923 0,09210189 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03050923 0,09198648 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03050923 0,09187135 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03050923 0,09175651 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03050923 0,09164196 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03050923 0,09152769 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03050923 0,09141371 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03050923 0,09130001 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03050923 0,0911866 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03050923 0,09107346 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03050923 0,09096061 ! spinal cord patterning GO:0021511 13 7 0,000 0,03050923 0,09084803 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03050923 0,09073573 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03050923 0,09062372 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03050923 0,09051197 ! adrenal gland development GO:0030325 17 7 0,000 0,03050923 0,0904005 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03050923 0,09028931 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03050923 0,09017839 ! ovulation GO:0030728 9 7 0,000 0,03050923 0,09006774 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03050923 0,08995736 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03050923 0,08984726 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03050923 0,08973742 ! microtubule nucleation GO:0007020 20 7 0,000 0,03050923 0,08962785 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03050923 0,08951855 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03050923 0,08940951 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03050923 0,08930074 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03050923 0,08919224 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03050923 0,08908399 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03050923 0,08897601 ! galactose metabolic process GO:0006012 13 7 0,000 0,03050923 0,08886829 ! vesicle fusion GO:0006906 17 7 0,000 0,03050923 0,08876083 ! response to dietary excess GO:0002021 8 7 0,000 0,03050923 0,08865363 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03050923 0,08854669 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03050923 0,08844001 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03050923 0,08833359 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03050923 0,08822742 ! purine salvage GO:0043101 10 7 0,000 0,03050923 0,0881215 ! nucleoside transport GO:0015858 8 7 0,000 0,03050923 0,08801584 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03050923 0,08791043 ! parturition GO:0007567 14 7 0,000 0,03050923 0,08780527 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03050923 0,08770037 ! rRNA modification GO:0000154 14 7 0,000 0,03050923 0,08759572 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03050923 0,08749131 ! spindle checkpoint GO:0031577 15 7 0,000 0,03050923 0,08738715 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03050923 0,08728325 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03050923 0,08717958 ! macrophage differentiation GO:0030225 11 7 0,000 0,03050923 0,08707617 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03050923 0,086973 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03050923 0,08687007 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03050923 0,08676739 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03050923 0,08666495 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03050923 0,08656275 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03050923 0,08646079 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03050923 0,08635907 ! eating behavior GO:0042755 7 7 0,000 0,03050923 0,08625759 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03050923 0,08615635 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03050923 0,08605535 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03050923 0,08595458 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03050923 0,08585405 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03050923 0,08575375 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03050923 0,08565369 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03050923 0,08555386 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03050923 0,08545426 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03050923 0,08535489 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03050923 0,08525576 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03050923 0,08515686 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03050923 0,08505818 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03050923 0,08495973 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03050923 0,08486151 ! regulation of meiosis GO:0040020 12 7 0,000 0,03050923 0,08476352 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03050923 0,08466575 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03050923 0,08456821 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03050923 0,0844709 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03050923 0,0843738 ! transcription termination GO:0006353 13 7 0,000 0,03050923 0,08427693 ! response to tumor cell GO:0002347 13 7 0,000 0,03050923 0,08418029 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03050923 0,08408386 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03050923 0,08398765 ! anaphase GO:0051322 17 7 0,000 0,03050923 0,08389167 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03050923 0,0837959 ! axonal fasciculation GO:0007413 18 7 0,000 0,03050923 0,08370035 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03050923 0,08360502 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03050923 0,08350991 ! diuresis GO:0030146 12 7 0,000 0,03050923 0,08341501 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03050923 0,08332033 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03050923 0,08322586 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03050923 0,08313161 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03050923 0,08303757 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03050923 0,08294374 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03050923 0,08285012 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03050923 0,08275672 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03050923 0,08266352 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03050923 0,08257054 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03050923 0,08247776 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03050923 0,0823852 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03050923 0,08229284 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,03050923 0,08220068 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03050923 0,08210874 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03050923 0,08201699 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03050923 0,08192546 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03050923 0,08183412 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03050923 0,08174299 ! adult feeding behavior GO:0008343 9 7 0,000 0,03050923 0,08165207 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03050923 0,08156134 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03050923 0,08147082 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03050923 0,0813805 ! muscle adaptation GO:0043500 14 7 0,000 0,03050923 0,08129038 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03050923 0,08120045 ! retina homeostasis GO:0001895 12 7 0,000 0,03050923 0,08111073 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03050923 0,0810212 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03050923 0,08093187 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03050923 0,08084274 ! protein prenylation GO:0018342 18 7 0,000 0,03050923 0,08075381 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03050923 0,08066507 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03050923 0,08057652 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03050923 0,08048817 ! viral reproductive process GO:0022415 126 62 1,000 0,03080344 0,08117533 ! gonad development GO:0008406 98 62 1,000 0,03080344 0,08108652 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,03080344 0,0809979 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,03265341 0,08576867 GO:0048609|reproductive process in a multicellular organism, ! germ cell development GO:0007281 118 65 1,000 0,03359442 0,08814415 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,03454597 0,09054206 ! secondary metabolic process GO:0019748 116 66 1,000 0,03454597 0,09044354 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0347916 0,09098761 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0347916 0,09088882 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0347916 0,09079024 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0347916 0,09069188 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0347916 0,09059372 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0347916 0,09049578 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0347916 0,09039806 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0347916 0,09030054 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0347916 0,09020323 ! meiotic prophase I GO:0007128 13 8 0,000 0,0347916 0,09010614 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0347916 0,09000925 ! oligopeptide transport GO:0006857 15 8 0,000 0,0347916 0,08991257 ! UTP metabolic process GO:0046051 8 8 0,000 0,0347916 0,0898161 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0347916 0,08971983 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0347916 0,08962377 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0347916 0,08952792 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0347916 0,08943227 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0347916 0,08933682 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0347916 0,08924158 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0347916 0,08914654 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0347916 0,0890517 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0347916 0,08895707 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0347916 0,08886263 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0347916 0,0887684 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0347916 0,08867437 ! reflex GO:0060004 16 8 0,000 0,0347916 0,08858053 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0347916 0,08848689 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0347916 0,08839345 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0347916 0,08830021 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0347916 0,08820717 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0347916 0,08811432 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0347916 0,08802166 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0347916 0,0879292 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0347916 0,08783694 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0347916 0,08774486 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0347916 0,08765298 ! histidine metabolic process GO:0006547 16 8 0,000 0,0347916 0,0875613 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0347916 0,0874698 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0347916 0,0873785 ! glycine catabolic process GO:0006546 13 8 0,000 0,0347916 0,08728738 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0347916 0,08719646 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0347916 0,08710572 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,0347916 0,08701518 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0347916 0,08692482 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0347916 0,08683465 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0347916 0,08674466 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0347916 0,08665487 ! macrophage activation GO:0042116 12 8 0,000 0,0347916 0,08656525 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0347916 0,08647583 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0347916 0,08638658 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0347916 0,08629753 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0347916 0,08620865 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0347916 0,08611996 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0347916 0,08603145 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0347916 0,08594312 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0347916 0,08585498 ! osteoblast development GO:0002076 16 8 0,000 0,0347916 0,08576701 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0347916 0,08567922 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0347916 0,08559162 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0347916 0,08550419 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0347916 0,08541694 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0347916 0,08532987 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0347916 0,08524297 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0347916 0,08515626 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0347916 0,08506972 ! intermediate filament organization GO:0045109 12 8 0,000 0,0347916 0,08498335 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0347916 0,08489716 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0347916 0,08481115 ! cellular extravasation GO:0045123 12 8 0,000 0,0347916 0,0847253 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0347916 0,08463964 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0347916 0,08455414 ! response to antibiotic GO:0046677 11 8 0,000 0,0347916 0,08446882 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0347916 0,08438367 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0347916 0,08429869 ! DNA topological change GO:0006265 12 8 0,000 0,0347916 0,08421388 ! response to tropane GO:0014073 15 8 0,000 0,0347916 0,08412925 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0347916 0,08404478 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0347916 0,08396048 ! melanosome transport GO:0032402 13 8 0,000 0,0347916 0,08387635 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0347916 0,08379239 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0347916 0,0837086 ! mast cell activation GO:0045576 14 8 0,000 0,0347916 0,08362498 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0347916 0,08354152 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0347916 0,08345823 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0347916 0,0833751 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0347916 0,08329214 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0347916 0,08320934 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0347916 0,08312671 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0347916 0,08304425 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0347916 0,08296194 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0347916 0,0828798 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0347916 0,08279782 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0347916 0,08271601 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0347916 0,08263435 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0347916 0,08255286 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0347916 0,08247153 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0347916 0,08239035 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0347916 0,08230934 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0347916 0,08222849 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0347916 0,08214779 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0347916 0,08206726 ! hormone catabolic process GO:0042447 17 8 0,000 0,0347916 0,08198688 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0347916 0,08190665 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0347916 0,08182659 ! ATP catabolic process GO:0006200 11 8 0,000 0,0347916 0,08174668 ! blastocyst growth GO:0001832 19 8 0,000 0,0347916 0,08166693 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0347916 0,08158733 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0347916 0,08150789 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0347916 0,0814286 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0347916 0,08134947 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0347916 0,08127049 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0347916 0,08119166 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0347916 0,08111299 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0347916 0,08103446 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0347916 0,08095609 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0347916 0,08087788 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0347916 0,08079981 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0347916 0,08072189 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0347916 0,08064412 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0347916 0,08056651 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0347916 0,08048904 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0347916 0,08041172 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0347916 0,08033455 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,03550795 0,08191 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,03648025 0,08407229 ! viral reproduction GO:0016032 134 68 1,000 0,03648025 0,08399184 ! regulation of lipase activity GO:0060191 130 68 1,000 0,03648025 0,08391154 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,03648025 0,0838314 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,03746275 0,08600704 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,03746275 0,08592505 ! regulation of developmental growth GO:0048638 15 9 0,000 0,0390552 0,08949221 ! axon extension GO:0048675 15 9 0,000 0,0390552 0,08940706 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0390552 0,08932207 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0390552 0,08923725 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0390552 0,08915258 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0390552 0,08906808 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0390552 0,08898373 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0390552 0,08889955 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0390552 0,08881552 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0390552 0,08873165 ! phosphate transport GO:0006817 19 9 0,000 0,0390552 0,08864794 ! reproductive behavior GO:0019098 19 9 0,000 0,0390552 0,08856439 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0390552 0,088481 ! CTP metabolic process GO:0046036 9 9 0,000 0,0390552 0,08839776 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0390552 0,08831468 ! GTP metabolic process GO:0046039 9 9 0,000 0,0390552 0,08823176 ! RNA methylation GO:0001510 15 9 0,000 0,0390552 0,08814899 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0390552 0,08806637 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0390552 0,08798391 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0390552 0,08790161 ! artery development GO:0060840 24 9 0,000 0,0390552 0,08781946 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0390552 0,08773746 ! regulation of glycolysis GO:0006110 21 9 0,000 0,0390552 0,08765562 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0390552 0,08757392 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0390552 0,08749238 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0390552 0,087411 ! chemosensory behavior GO:0007635 20 9 0,000 0,0390552 0,08732976 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0390552 0,08724867 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0390552 0,08716774 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0390552 0,08708695 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0390552 0,08700632 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0390552 0,08692583 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0390552 0,08684549 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0390552 0,0867653 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0390552 0,08668526 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0390552 0,08660536 ! protein targeting to ER GO:0045047 22 9 0,000 0,0390552 0,08652562 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0390552 0,08644602 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0390552 0,08636656 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0390552 0,08628726 ! endosome organization GO:0007032 17 9 0,000 0,0390552 0,08620809 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0390552 0,08612908 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0390552 0,0860502 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0390552 0,08597147 ! mannose metabolic process GO:0006013 13 9 0,000 0,0390552 0,08589289 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0390552 0,08581445 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0390552 0,08573615 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0390552 0,085658 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0390552 0,08557998 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0390552 0,08550211 ! ruffle organization GO:0031529 15 9 0,000 0,0390552 0,08542438 ! retinol metabolic process GO:0042572 18 9 0,000 0,0390552 0,08534679 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0390552 0,08526935 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0390552 0,08519204 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0390552 0,08511487 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0390552 0,08503785 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,0390552 0,08496096 ! protein heterooligomerization GO:0051291 16 9 0,000 0,0390552 0,08488421 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0390552 0,0848076 ! segment specification GO:0007379 13 9 0,000 0,0390552 0,08473113 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0390552 0,08465479 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0390552 0,0845786 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0390552 0,08450254 ! response to amine stimulus GO:0014075 13 9 0,000 0,0390552 0,08442661 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0390552 0,08435083 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0390552 0,08427518 ! erythrocyte development GO:0048821 15 9 0,000 0,0390552 0,08419966 ! gas homeostasis GO:0033483 16 9 0,000 0,0390552 0,08412428 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0390552 0,08404903 ! renal water homeostasis GO:0003091 14 9 0,000 0,0390552 0,08397392 ! postreplication repair GO:0006301 22 9 0,000 0,0390552 0,08389895 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0390552 0,0838241 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0390552 0,08374939 ! icosanoid secretion GO:0032309 15 9 0,000 0,0390552 0,08367482 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0390552 0,08360037 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0390552 0,08352606 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0390552 0,08345188 ! regulation of cell division GO:0051302 15 9 0,000 0,0390552 0,08337784 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0390552 0,08330392 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0390552 0,08323013 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0390552 0,08315648 ! sterol catabolic process GO:0016127 11 9 0,000 0,0390552 0,08308295 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0390552 0,08300956 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0390552 0,08293629 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0390552 0,08286316 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0390552 0,08279015 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0390552 0,08271727 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0390552 0,08264452 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0390552 0,0825719 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0390552 0,0824994 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0390552 0,08242704 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0390552 0,08235479 ! purine base metabolic process GO:0006144 21 9 0,000 0,0390552 0,08228268 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0390552 0,08221069 ! pigment granule transport GO:0051904 17 9 0,000 0,0390552 0,08213883 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0390552 0,08206709 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0390552 0,08199548 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0390552 0,08192399 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0390552 0,08185263 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0390552 0,08178139 ! mitochondrion localization GO:0051646 15 9 0,000 0,0390552 0,08171028 ! humoral immune response GO:0006959 109 71 1,000 0,03945796 0,0824812 ! B cell activation GO:0042113 160 71 1,000 0,03945796 0,0824096 ! regulation of caspase activity GO:0043281 122 72 1,000 0,04047045 0,08445092 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,04047045 0,08437774 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,04047045 0,08430469 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,04047045 0,08423176 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,04047045 0,08415896 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,04047045 0,08408628 ! meiosis GO:0007126 121 74 1,000 0,04252468 0,08827816 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,04252468 0,08820206 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04330011 0,08973305 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04330011 0,08965582 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04330011 0,08957873 ! synapsis GO:0007129 13 10 0,000 0,04330011 0,08950178 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04330011 0,08942495 ! N-glycan processing GO:0006491 20 10 0,000 0,04330011 0,08934826 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04330011 0,08927169 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04330011 0,08919526 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04330011 0,08911896 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04330011 0,08904279 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04330011 0,08896675 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04330011 0,08889084 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04330011 0,08881506 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04330011 0,08873941 ! androgen metabolic process GO:0008209 17 10 0,000 0,04330011 0,08866389 ! phospholipid efflux GO:0033700 16 10 0,000 0,04330011 0,08858849 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04330011 0,08851323 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04330011 0,08843809 ! lung alveolus development GO:0048286 26 10 0,000 0,04330011 0,08836308 ! pathogenesis GO:0009405 13 10 0,000 0,04330011 0,08828819 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04330011 0,08821344 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04330011 0,0881388 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04330011 0,0880643 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04330011 0,08798992 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04330011 0,08791567 ! endoderm development GO:0007492 16 10 0,000 0,04330011 0,08784154 ! arginine catabolic process GO:0006527 13 10 0,000 0,04330011 0,08776754 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04330011 0,08769366 ! proline metabolic process GO:0006560 13 10 0,000 0,04330011 0,0876199 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04330011 0,08754627 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04330011 0,08747277 ! V(D)J recombination GO:0033151 28 10 0,000 0,04330011 0,08739939 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04330011 0,08732612 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04330011 0,08725299 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04330011 0,08717997 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04330011 0,08710708 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04330011 0,08703431 ! multicellular organism growth GO:0035264 18 10 0,000 0,04330011 0,08696166 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04330011 0,08688913 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04330011 0,08681672 ! epithelial cell development GO:0002064 20 10 0,000 0,04330011 0,08674444 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04330011 0,08667227 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04330011 0,08660022 ! macroautophagy GO:0016236 17 10 0,000 0,04330011 0,08652829 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04330011 0,08645649 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04330011 0,0863848 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04330011 0,08631323 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04330011 0,08624178 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04330011 0,08617044 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04330011 0,08609923 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04330011 0,08602813 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04330011 0,08595715 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04330011 0,08588629 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04330011 0,08581554 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04330011 0,08574491 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04330011 0,0856744 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04330011 0,085604 ! response to dsRNA GO:0043331 20 10 0,000 0,04330011 0,08553372 ! DNA ligation GO:0006266 19 10 0,000 0,04330011 0,08546355 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04330011 0,0853935 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04330011 0,08532356 ! melanosome localization GO:0032400 16 10 0,000 0,04330011 0,08525374 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04330011 0,08518403 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04330011 0,08511443 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04330011 0,08504495 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04330011 0,08497558 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04330011 0,08490633 ! mRNA cleavage GO:0006379 17 10 0,000 0,04330011 0,08483719 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04330011 0,08476816 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04330011 0,08469924 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04330011 0,08463044 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04330011 0,08456174 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04330011 0,08449316 ! salivary gland development GO:0007431 27 10 0,000 0,04330011 0,08442469 ! prophase GO:0051324 15 10 0,000 0,04330011 0,08435633 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04330011 0,08428808 ! apical protein localization GO:0045176 15 10 0,000 0,04330011 0,08421994 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04330011 0,08415191 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04330011 0,08408399 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04330011 0,08401618 ! midbrain development GO:0030901 13 10 0,000 0,04330011 0,08394848 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04330011 0,08388089 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04330011 0,08381341 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04330011 0,08374603 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04330011 0,08367877 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04330011 0,08361161 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04330011 0,08354456 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04330011 0,08347762 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04330011 0,08341078 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04330011 0,08334405 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04330011 0,08327743 ! blastocyst formation GO:0001825 17 10 0,000 0,04330011 0,08321092 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04330011 0,08314451 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04330011 0,0830782 ! activation of innate immune response GO:0002218 12 10 0,000 0,04330011 0,08301201 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04330011 0,08294591 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04330011 0,08287993 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04330011 0,08281404 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04330011 0,08274827 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04330011 0,08268259 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,04356621 0,08312475 ! meiotic cell cycle GO:0051321 122 75 1,000 0,04356621 0,08305888 ! rhythmic process GO:0048511 128 75 1,000 0,04356621 0,08299312 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04356621 0,08292746 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,04461722 0,08486089 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,04567759 0,08680906 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,04567759 0,08674055 ! blood coagulation GO:0007596 146 78 1,000 0,04674722 0,08870175 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,04674722 0,08863185 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04752641 0,09003822 ! respiratory burst GO:0045730 17 11 0,000 0,04752641 0,08996738 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04752641 0,08989665 ! neuron fate specification GO:0048665 17 11 0,000 0,04752641 0,08982603 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04752641 0,08975552 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04752641 0,08968513 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04752641 0,08961484 ! thyroid gland development GO:0030878 26 11 0,000 0,04752641 0,08954466 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04752641 0,0894746 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04752641 0,08940464 ! response to pain GO:0048265 24 11 0,000 0,04752641 0,08933479 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04752641 0,08926505 ! T cell proliferation GO:0042098 26 11 0,000 0,04752641 0,08919542 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04752641 0,0891259 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04752641 0,08905649 ! bone resorption GO:0045453 16 11 0,000 0,04752641 0,08898719 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04752641 0,08891799 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04752641 0,0888489 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04752641 0,08877992 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04752641 0,08871104 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04752641 0,08864227 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04752641 0,08857361 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04752641 0,08850506 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04752641 0,08843661 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04752641 0,08836826 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04752641 0,08830003 ! lipid digestion GO:0044241 18 11 0,000 0,04752641 0,08823189 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04752641 0,08816387 ! UV protection GO:0009650 19 11 0,000 0,04752641 0,08809594 ! adult heart development GO:0007512 14 11 0,000 0,04752641 0,08802813 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04752641 0,08796041 ! temperature homeostasis GO:0001659 17 11 0,000 0,04752641 0,0878928 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04752641 0,0878253 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04752641 0,08775789 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04752641 0,08769059 ! regulation of organ growth GO:0046620 13 11 0,000 0,04752641 0,0876234 ! pigment granule localization GO:0051875 20 11 0,000 0,04752641 0,08755631 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04752641 0,08748931 ! vasoconstriction GO:0042310 18 11 0,000 0,04752641 0,08742243 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04752641 0,08735564 ! embryonic axis specification GO:0000578 18 11 0,000 0,04752641 0,08728896 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04752641 0,08722238 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04752641 0,0871559 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04752641 0,08708952 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04752641 0,08702324 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04752641 0,08695706 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04752641 0,08689098 ! zymogen activation GO:0031638 15 11 0,000 0,04752641 0,08682501 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04752641 0,08675913 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04752641 0,08669335 ! nucleosome positioning GO:0016584 15 11 0,000 0,04752641 0,08662768 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04752641 0,0865621 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04752641 0,08649662 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04752641 0,08643124 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04752641 0,08636596 ! acid secretion GO:0046717 18 11 0,000 0,04752641 0,08630078 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04752641 0,0862357 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04752641 0,08617071 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04752641 0,08610582 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04752641 0,08604103 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04752641 0,08597634 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,04752641 0,08591175 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04752641 0,08584725 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04752641 0,08578285 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04752641 0,08571854 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04752641 0,08565433 ! embryonic gut development GO:0048566 15 11 0,000 0,04752641 0,08559022 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04752641 0,0855262 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04752641 0,08546228 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04752641 0,08539846 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04752641 0,08533473 ! defense response to fungus GO:0050832 13 11 0,000 0,04752641 0,08527109 ! developmental induction GO:0031128 19 11 0,000 0,04752641 0,08520755 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04752641 0,08514411 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04752641 0,08508075 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04752641 0,0850175 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04752641 0,08495433 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04752641 0,08489127 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04752641 0,08482829 ! nucleus localization GO:0051647 19 11 0,000 0,04752641 0,08476541 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04752641 0,08470262 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,04782603 0,08517352 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,04782603 0,08511052 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,04782603 0,08504762 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,0489139 0,0869179 ! muscle cell differentiation GO:0042692 159 80 1,000 0,0489139 0,08685376 ! T cell activation GO:0042110 168 81 1,000 0,05001073 0,08873586 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,05001073 0,08867047 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,05001073 0,08860517 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,05111644 0,09049753 ! response to drug GO:0042493 143 82 1,000 0,05111644 0,09043099 ! response to nutrient GO:0007584 125 82 1,000 0,05111644 0,09036454 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,05111644 0,0902982 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05173417 0,09132239 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05173417 0,09125544 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05173417 0,09118858 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05173417 0,09112183 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05173417 0,09105517 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05173417 0,09098861 ! cartilage condensation GO:0001502 20 12 0,000 0,05173417 0,09092215 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05173417 0,09085578 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05173417 0,09078951 ! protein complex disassembly GO:0043241 27 12 0,000 0,05173417 0,09072334 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05173417 0,09065726 ! hippocampus development GO:0021766 26 12 0,000 0,05173417 0,09059128 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05173417 0,0905254 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05173417 0,09045961 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05173417 0,09039391 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05173417 0,09032832 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05173417 0,09026281 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05173417 0,0901974 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05173417 0,09013209 ! drug transport GO:0015893 16 12 0,000 0,05173417 0,09006687 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05173417 0,09000175 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05173417 0,08993672 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05173417 0,08987178 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05173417 0,08980694 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05173417 0,08974219 ! forebrain cell migration GO:0021885 21 12 0,000 0,05173417 0,08967753 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05173417 0,08961297 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05173417 0,0895485 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05173417 0,08948413 ! entry into host cell GO:0030260 32 12 0,000 0,05173417 0,08941984 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,05173417 0,08935565 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05173417 0,08929155 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05173417 0,08922754 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05173417 0,08916362 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05173417 0,0890998 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05173417 0,08903606 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05173417 0,08897242 ! protein homotetramerization GO:0051289 21 12 0,000 0,05173417 0,08890887 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05173417 0,08884541 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05173417 0,08878204 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05173417 0,08871876 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05173417 0,08865557 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05173417 0,08859247 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05173417 0,08852946 ! cranial nerve development GO:0021545 20 12 0,000 0,05173417 0,08846654 ! fucose catabolic process GO:0019317 22 12 0,000 0,05173417 0,08840371 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05173417 0,08834096 ! histone methylation GO:0016571 26 12 0,000 0,05173417 0,08827831 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05173417 0,08821575 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05173417 0,08815327 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05173417 0,08809088 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05173417 0,08802858 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05173417 0,08796637 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05173417 0,08790425 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05173417 0,08784221 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05173417 0,08778027 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05173417 0,08771841 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,05173417 0,08765663 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05173417 0,08759495 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05173417 0,08753335 ! response to cold GO:0009409 17 12 0,000 0,05173417 0,08747183 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05173417 0,08741041 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05173417 0,08734907 ! regulation of lyase activity GO:0051339 160 83 1,000 0,05223091 0,08812592 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,05335405 0,08995784 ! hemostasis GO:0007599 158 84 1,000 0,05335405 0,08989485 ! regulation of ligase activity GO:0051340 142 84 1,000 0,05335405 0,08983194 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,05448576 0,09167325 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 1,000 0,05562596 0,09352624 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05592349 0,09396083 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05592349 0,09389526 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05592349 0,09382979 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05592349 0,0937644 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05592349 0,0936991 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05592349 0,0936339 ! lipid localization GO:0010876 28 13 0,000 0,05592349 0,09356878 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05592349 0,09350376 ! organelle fusion GO:0048284 32 13 0,000 0,05592349 0,09343883 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05592349 0,09337398 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05592349 0,09330923 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05592349 0,09324457 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05592349 0,09317999 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05592349 0,09311551 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05592349 0,09305112 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05592349 0,09298681 ! methionine metabolic process GO:0006555 27 13 0,000 0,05592349 0,09292259 ! plasma membrane organization GO:0007009 24 13 0,000 0,05592349 0,09285846 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05592349 0,09279442 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05592349 0,09273047 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05592349 0,09266661 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05592349 0,09260283 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05592349 0,09253914 ! response to X-ray GO:0010165 25 13 0,000 0,05592349 0,09247554 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05592349 0,09241203 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05592349 0,0923486 ! exocrine system development GO:0035272 32 13 0,000 0,05592349 0,09228526 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05592349 0,09222201 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05592349 0,09215884 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05592349 0,09209576 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05592349 0,09203277 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05592349 0,09196986 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05592349 0,09190704 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05592349 0,09184431 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05592349 0,09178166 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05592349 0,0917191 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05592349 0,09165662 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05592349 0,09159422 ! ribosome assembly GO:0042255 17 13 0,000 0,05592349 0,09153191 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05592349 0,09146969 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05592349 0,09140755 ! chromatin silencing GO:0006342 26 13 0,000 0,05592349 0,09134549 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05592349 0,09128352 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05592349 0,09122164 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05592349 0,09115983 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05592349 0,09109811 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05592349 0,09103648 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05592349 0,09097492 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05592349 0,09091345 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05592349 0,09085207 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05592349 0,09079076 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05592349 0,09072954 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05592349 0,0906684 ! embryonic placenta development GO:0001892 23 13 0,000 0,05592349 0,09060735 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05592349 0,09054637 ! insulin secretion GO:0030073 23 13 0,000 0,05592349 0,09048548 ! actin filament polymerization GO:0030041 24 13 0,000 0,05592349 0,09042467 ! acrosome reaction GO:0007340 18 13 0,000 0,05592349 0,09036394 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,05677453 0,09167753 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,05793139 0,09348285 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,05909645 0,09529896 ! rRNA transcription GO:0009303 25 14 0,000 0,06009443 0,09684341 ! lactation GO:0007595 26 14 0,000 0,06009443 0,09677859 ! reproductive cellular process GO:0048610 20 14 0,000 0,06009443 0,09671385 ! tRNA modification GO:0006400 20 14 0,000 0,06009443 0,0966492 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06009443 0,09658464 ! regulation of S phase GO:0033261 23 14 0,000 0,06009443 0,09652017 ! water transport GO:0006833 21 14 0,000 0,06009443 0,09645578 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06009443 0,09639147 ! non-recombinational repair GO:0000726 25 14 0,000 0,06009443 0,09632726 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06009443 0,09626312 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06009443 0,09619908 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06009443 0,09613511 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06009443 0,09607124 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06009443 0,09600744 ! palate development GO:0060021 31 14 0,000 0,06009443 0,09594374 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,06009443 0,09588011 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06009443 0,09581657 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06009443 0,09575312 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06009443 0,09568975 ! arginine metabolic process GO:0006525 17 14 0,000 0,06009443 0,09562646 ! regulation of heart rate GO:0002027 24 14 0,000 0,06009443 0,09556326 ! organic alcohol transport GO:0015850 29 14 0,000 0,06009443 0,09550014 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06009443 0,0954371 ! embryo implantation GO:0007566 30 14 0,000 0,06009443 0,09537415 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06009443 0,09531128 ! L-amino acid transport GO:0015807 30 14 0,000 0,06009443 0,09524849 ! bone mineralization GO:0030282 17 14 0,000 0,06009443 0,09518579 ! stem cell development GO:0048864 43 14 0,000 0,06009443 0,09512316 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06009443 0,09506062 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06009443 0,09499817 ! cerebellum development GO:0021549 21 14 0,000 0,06009443 0,09493579 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06009443 0,0948735 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06009443 0,09481129 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06009443 0,09474915 ! cofactor transport GO:0051181 26 14 0,000 0,06009443 0,09468711 ! NADP metabolic process GO:0006739 24 14 0,000 0,06009443 0,09462514 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06009443 0,09456325 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06009443 0,09450144 ! intestinal absorption GO:0050892 25 14 0,000 0,06009443 0,09443972 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06009443 0,09437807 ! oxygen transport GO:0015671 21 14 0,000 0,06009443 0,09431651 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06009443 0,09425503 ! male genitalia development GO:0030539 24 14 0,000 0,06009443 0,09419362 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06009443 0,0941323 ! regulation of axon extension GO:0030516 37 14 0,000 0,06009443 0,09407105 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06009443 0,09400989 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,0602696 0,09422265 ! response to protein stimulus GO:0051789 149 91 1,000 0,06145076 0,09600684 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,06383673 0,0996698 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,06383673 0,09960516 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06424709 0,10018049 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06424709 0,10011561 ! superoxide anion generation GO:0042554 20 15 0,000 0,06424709 0,10005081 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06424709 0,0999861 ! copper ion transport GO:0006825 20 15 0,000 0,06424709 0,09992146 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06424709 0,09985691 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06424709 0,09979245 ! sulfate transport GO:0008272 23 15 0,000 0,06424709 0,09972807 ! response to cAMP GO:0051591 22 15 0,000 0,06424709 0,09966377 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06424709 0,09959955 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06424709 0,09953542 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06424709 0,09947137 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06424709 0,0994074 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06424709 0,09934351 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06424709 0,09927971 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06424709 0,09921598 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06424709 0,09915234 ! pituitary gland development GO:0021983 29 15 0,000 0,06424709 0,09908878 ! vesicle coating GO:0006901 33 15 0,000 0,06424709 0,09902531 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06424709 0,09896191 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06424709 0,09889859 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,06424709 0,09883536 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06424709 0,09877221 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,06424709 0,09870913 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06424709 0,09864614 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06424709 0,09858323 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06424709 0,0985204 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06424709 0,09845765 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06424709 0,09839497 ! histone deacetylation GO:0016575 20 15 0,000 0,06424709 0,09833238 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06424709 0,09826987 ! tissue regeneration GO:0042246 26 15 0,000 0,06424709 0,09820744 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06424709 0,09814508 ! water homeostasis GO:0030104 27 15 0,000 0,06424709 0,09808281 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06424709 0,09802061 ! muscle maintenance GO:0046716 26 15 0,000 0,06424709 0,09795849 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06424709 0,09789646 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06424709 0,0978345 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06424709 0,09777261 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06424709 0,09771081 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06424709 0,09764909 ! cell killing GO:0001906 29 15 0,000 0,06424709 0,09758744 ! detection of bacterium GO:0016045 18 15 0,000 0,06424709 0,09752587 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06424709 0,09746438 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06424709 0,09740296 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06424709 0,09734163 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06424709 0,09728037 ! peptide hormone processing GO:0016486 23 15 0,000 0,06424709 0,09721918 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,06504135 0,0983592 ! female pregnancy GO:0007565 164 94 1,000 0,06504135 0,09829742 ! leukocyte differentiation GO:0002521 202 96 1,000 0,06747343 0,10190903 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06838154 0,1032158 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06838154 0,10315109 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06838154 0,10308646 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06838154 0,10302191 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06838154 0,10295744 ! bone remodeling GO:0046849 27 16 0,000 0,06838154 0,10289305 ! filopodium assembly GO:0046847 32 16 0,000 0,06838154 0,10282874 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06838154 0,10276451 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06838154 0,10270036 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06838154 0,1026363 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06838154 0,10257231 ! startle response GO:0001964 28 16 0,000 0,06838154 0,1025084 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06838154 0,10244457 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06838154 0,10238082 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06838154 0,10231715 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06838154 0,10225356 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06838154 0,10219005 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06838154 0,10212662 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06838154 0,10206327 ! response to osmotic stress GO:0006970 25 16 0,000 0,06838154 0,10199999 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06838154 0,10193679 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06838154 0,10187367 ! fructose metabolic process GO:0006000 25 16 0,000 0,06838154 0,10181063 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06838154 0,10174767 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06838154 0,10168479 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06838154 0,10162198 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06838154 0,10155925 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06838154 0,1014966 ! axon cargo transport GO:0008088 43 16 0,000 0,06838154 0,10143402 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06838154 0,10137152 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06838154 0,1013091 ! DNA replication initiation GO:0006270 27 16 0,000 0,06838154 0,10124676 ! neuron recognition GO:0008038 35 16 0,000 0,06838154 0,10118449 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06838154 0,1011223 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06838154 0,10106019 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06838154 0,10099815 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06838154 0,10093619 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06838154 0,1008743 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06838154 0,10081249 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06838154 0,10075076 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06838154 0,1006891 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06838154 0,10062751 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06838154 0,100566 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06838154 0,10050457 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06838154 0,10044321 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,07117729 0,10448601 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,07117729 0,1044223 GO:0060538|skeletal muscle organ development, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07249786 0,10629485 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07249786 0,10623011 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07249786 0,10616545 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,07249786 0,10610088 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07249786 0,10603638 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07249786 0,10597196 ! endothelial cell migration GO:0043542 28 17 0,000 0,07249786 0,10590762 ! inositol metabolic process GO:0006020 28 17 0,000 0,07249786 0,10584335 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07249786 0,10577916 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07249786 0,10571506 ! glial cell development GO:0021782 27 17 0,000 0,07249786 0,10565102 ! limbic system development GO:0021761 36 17 0,000 0,07249786 0,10558707 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07249786 0,1055232 ! adult walking behavior GO:0007628 33 17 0,000 0,07249786 0,1054594 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07249786 0,10539568 ! heart looping GO:0001947 30 17 0,000 0,07249786 0,10533203 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07249786 0,10526846 ! myoblast differentiation GO:0045445 45 17 0,000 0,07249786 0,10520497 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07249786 0,10514156 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07249786 0,10507822 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07249786 0,10501496 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07249786 0,10495177 ! glycine metabolic process GO:0006544 28 17 0,000 0,07249786 0,10488866 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07249786 0,10482563 ! NAD metabolic process GO:0019674 29 17 0,000 0,07249786 0,10476267 ! membrane budding GO:0006900 37 17 0,000 0,07249786 0,10469979 ! DNA integration GO:0015074 29 17 0,000 0,07249786 0,10463698 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07249786 0,10457425 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07249786 0,10451159 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07249786 0,10444901 ! genitalia development GO:0048806 30 17 0,000 0,07249786 0,1043865 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07249786 0,10432407 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07249786 0,10426171 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07249786 0,10419943 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07249786 0,10413722 ! steroid catabolic process GO:0006706 31 17 0,000 0,07249786 0,10407508 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07249786 0,10401302 ! gas transport GO:0015669 25 17 0,000 0,07249786 0,10395104 ! organic cation transport GO:0015695 31 17 0,000 0,07249786 0,10388913 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07249786 0,10382729 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07249786 0,10376552 ! microspike assembly GO:0030035 36 17 0,000 0,07249786 0,10370383 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07249786 0,10364221 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07249786 0,10358067 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07659612 0,10937108 ! neuron maturation GO:0042551 42 18 0,000 0,07659612 0,10930621 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07659612 0,10924142 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07659612 0,1091767 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07659612 0,10911206 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07659612 0,1090475 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07659612 0,10898301 ! memory GO:0007613 31 18 0,000 0,07659612 0,1089186 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07659612 0,10885426 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07659612 0,10879 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07659612 0,10872582 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07659612 0,10866171 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07659612 0,10859768 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07659612 0,10853373 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07659612 0,10846985 ! response to retinoic acid GO:0032526 26 18 0,000 0,07659612 0,10840604 ! response to fungus GO:0009620 21 18 0,000 0,07659612 0,10834231 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07659612 0,10827865 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07659612 0,10821507 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07659612 0,10815157 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07659612 0,10808813 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07659612 0,10802478 ! vitamin transport GO:0051180 27 18 0,000 0,07659612 0,10796149 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07659612 0,10789828 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07659612 0,10783515 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07659612 0,10777209 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07659612 0,1077091 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07659612 0,10764618 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07659612 0,10758334 ! nerve development GO:0021675 28 18 0,000 0,07659612 0,10752058 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07659612 0,10745788 ! protein secretion GO:0009306 39 19 0,000 0,08067641 0,11311623 ! positive regulation of translation GO:0045727 30 19 0,000 0,08067641 0,11305035 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08067641 0,11298455 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08067641 0,11291882 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,08067641 0,11285317 ! skin development GO:0043588 36 19 0,000 0,08067641 0,1127876 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08067641 0,1127221 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08067641 0,11265668 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08067641 0,11259133 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08067641 0,11252606 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,08067641 0,11246086 ! cerebral cortex development GO:0021987 36 19 0,000 0,08067641 0,11239574 ! pigmentation during development GO:0048066 41 19 0,000 0,08067641 0,1123307 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08067641 0,11226573 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,08067641 0,11220084 ! heme metabolic process GO:0042168 36 19 0,000 0,08067641 0,11213602 ! actin filament bundle formation GO:0051017 42 19 0,000 0,08067641 0,11207128 ! neuromuscular junction development GO:0007528 34 19 0,000 0,08067641 0,11200661 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08067641 0,11194201 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08067641 0,11187749 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08067641 0,11181305 ! peptide cross-linking GO:0018149 37 19 0,000 0,08067641 0,11174868 ! protein export from nucleus GO:0006611 36 19 0,000 0,08067641 0,11168438 ! heart process GO:0003015 30 19 0,000 0,08067641 0,11162016 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08067641 0,11155601 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08067641 0,11149193 ! visual learning GO:0008542 36 19 0,000 0,08067641 0,11142793 ! G1 phase GO:0051318 40 19 0,000 0,08067641 0,111364 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08067641 0,11130014 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08067641 0,11123636 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,08067641 0,11117265 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08067641 0,11110902 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08067641 0,11104545 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08067641 0,11098196 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08067641 0,11091854 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08067641 0,1108552 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08067641 0,11079192 ! cilium assembly GO:0042384 37 19 0,000 0,08067641 0,11072872 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08067641 0,11066559 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08473881 0,11617184 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08473881 0,11610568 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08473881 0,1160396 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08473881 0,11597359 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08473881 0,11590766 ! response to vitamin GO:0033273 31 20 0,000 0,08473881 0,11584181 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08473881 0,11577602 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08473881 0,11571032 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08473881 0,11564469 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08473881 0,11557913 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08473881 0,11551364 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08473881 0,11544823 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08473881 0,1153829 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08473881 0,11531764 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08473881 0,11525245 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,08473881 0,11518733 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08473881 0,11512229 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08473881 0,11505732 ! body fluid secretion GO:0007589 31 20 0,000 0,08473881 0,11499243 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08473881 0,11492761 ! peptide secretion GO:0002790 35 20 0,000 0,08473881 0,11486286 ! stem cell differentiation GO:0048863 53 20 0,000 0,08473881 0,11479819 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08473881 0,11473358 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08473881 0,11466905 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08473881 0,1146046 ! sensory perception of pain GO:0019233 30 20 0,000 0,08473881 0,11454021 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08473881 0,1144759 ! diencephalon development GO:0021536 34 20 0,000 0,08473881 0,11441166 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08473881 0,11434749 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08473881 0,1142834 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08473881 0,11421937 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08473881 0,11415542 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08473881 0,11409154 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08473881 0,11402773 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08473881 0,11396399 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08473881 0,11390032 ! regulation of glucose import GO:0046324 29 20 0,000 0,08473881 0,11383673 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08473881 0,1137732 ! actin filament-based movement GO:0030048 43 20 0,000 0,08473881 0,11370975 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,08473881 0,11364637 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08473881 0,11358305 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,08473881 0,11351981 ! regulation of cell killing GO:0031341 42 21 0,000 0,08878339 0,11887192 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08878339 0,11880581 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08878339 0,11873977 ! hormone secretion GO:0046879 38 21 0,000 0,08878339 0,1186738 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08878339 0,11860791 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08878339 0,11854209 ! axis specification GO:0009798 38 21 0,000 0,08878339 0,11847634 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08878339 0,11841067 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08878339 0,11834506 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08878339 0,11827954 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08878339 0,11821408 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08878339 0,11814869 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08878339 0,11808338 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,08878339 0,11801814 ! cytolysis GO:0019835 24 21 0,000 0,08878339 0,11795298 ! vasodilation GO:0042311 39 21 0,000 0,08878339 0,11788788 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08878339 0,11782286 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08878339 0,11775791 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08878339 0,11769302 ! DNA modification GO:0006304 34 21 0,000 0,08878339 0,11762822 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08878339 0,11756348 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,08878339 0,11749881 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08878339 0,11743422 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08878339 0,11736969 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,08878339 0,11730524 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08878339 0,11724086 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08878339 0,11717654 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08878339 0,1171123 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08878339 0,11704813 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08878339 0,11698403 ! collagen catabolic process GO:0030574 28 21 0,000 0,08878339 0,11692 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08878339 0,11685604 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09281023 0,12208935 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09281023 0,12202263 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09281023 0,12195599 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09281023 0,12188942 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09281023 0,12182292 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09281023 0,1217565 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09281023 0,12169015 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09281023 0,12162387 ! keratinization GO:0031424 28 22 0,000 0,09281023 0,12155766 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,09281023 0,12149152 ! sensory perception of taste GO:0050909 28 22 0,000 0,09281023 0,12142546 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,09281023 0,12135947 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09281023 0,12129355 ! vacuolar transport GO:0007034 36 22 0,000 0,09281023 0,1212277 ! lysosome organization GO:0007040 41 22 0,000 0,09281023 0,12116192 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09281023 0,12109621 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09281023 0,12103058 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09281023 0,12096502 ! fucose metabolic process GO:0006004 39 22 0,000 0,09281023 0,12089952 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09281023 0,1208341 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09281023 0,12076875 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09281023 0,12070347 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09281023 0,12063826 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09281023 0,12057312 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09281023 0,12050805 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09281023 0,12044305 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,09281023 0,12037812 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09281023 0,12031327 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09681941 0,12544292 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,09681941 0,12537541 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,09681941 0,12530796 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09681941 0,12524059 ! gluconeogenesis GO:0006094 33 23 0,000 0,09681941 0,1251733 ! viral genome replication GO:0019079 41 23 0,000 0,09681941 0,12510607 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09681941 0,12503892 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09681941 0,12497184 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09681941 0,12490483 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09681941 0,12483789 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09681941 0,12477103 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09681941 0,12470423 ! visual behavior GO:0007632 42 23 0,000 0,09681941 0,12463751 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,09681941 0,12457086 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09681941 0,12450428 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09681941 0,12443777 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09681941 0,12437133 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09681941 0,12430496 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09681941 0,12423867 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09681941 0,12417244 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,09681941 0,12410629 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09681941 0,1240402 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09681941 0,12397419 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09681941 0,12390825 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09681941 0,12384237 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09681941 0,12377657 ! fatty acid transport GO:0015908 44 23 0,000 0,09681941 0,12371084 ! platelet activation GO:0030168 37 23 0,000 0,09681941 0,12364517 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09681941 0,12357958 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09681941 0,12351405 ! hormone transport GO:0009914 40 23 0,000 0,09681941 0,1234486 ! cell-cell recognition GO:0009988 25 23 0,000 0,09681941 0,12338321 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09681941 0,1233179 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09681941 0,12325265 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09681941 0,12318747 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09681941 0,12312236 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,10081101 0,12813063 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10081101 0,12806298 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10081101 0,1279954 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10081101 0,12792789 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10081101 0,12786045 ! vesicle docking GO:0048278 47 24 0,000 0,10081101 0,12779309 ! spinal cord development GO:0021510 47 24 0,000 0,10081101 0,12772579 ! vacuole organization GO:0007033 43 24 0,000 0,10081101 0,12765857 ! digestive system process GO:0022600 39 24 0,000 0,10081101 0,12759141 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10081101 0,12752433 ! regulation of behavior GO:0050795 43 24 0,000 0,10081101 0,12745732 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10081101 0,12739038 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10081101 0,12732351 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10081101 0,1272567 ! membrane depolarization GO:0051899 39 24 0,000 0,10081101 0,12718997 ! pallium development GO:0021543 49 24 0,000 0,10081101 0,12712331 ! pentose metabolic process GO:0019321 35 24 0,000 0,10081101 0,12705672 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10081101 0,1269902 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10081101 0,12692375 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10081101 0,12685736 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10081101 0,12679105 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10081101 0,12672481 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10081101 0,12665863 ! regulation of amine transport GO:0051952 40 24 0,000 0,10081101 0,12659253 ! protein tetramerization GO:0051262 52 24 0,000 0,10081101 0,12652649 ! myelination GO:0042552 45 25 0,000 0,10478509 0,13144574 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10478509 0,13137724 ! phototransduction GO:0007602 33 25 0,000 0,10478509 0,13130882 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10478509 0,13124046 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,10478509 0,13117218 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,10478509 0,13110397 ! sperm motility GO:0030317 31 25 0,000 0,10478509 0,13103582 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10478509 0,13096775 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,10478509 0,13089975 ! chromosome condensation GO:0030261 45 25 0,000 0,10478509 0,13083183 ! response to starvation GO:0042594 42 25 0,000 0,10478509 0,13076397 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,10478509 0,13069618 ! neural crest cell development GO:0014032 54 25 0,000 0,10478509 0,13062846 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10478509 0,13056081 ! negative regulation of cell development GO:0010721 73 25 0,000 0,10478509 0,13049323 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10478509 0,13042573 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10478509 0,13035829 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10478509 0,13029092 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10478509 0,13022362 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10478509 0,13015639 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10478509 0,13008923 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10478509 0,13002214 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10478509 0,12995512 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,10478509 0,12988816 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10478509 0,12982128 ! telomere organization GO:0032200 43 25 0,000 0,10478509 0,12975447 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10478509 0,12968772 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10478509 0,12962104 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10874174 0,13444637 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10874174 0,13437732 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,10874174 0,13430833 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,10874174 0,13423942 ! initiation of viral infection GO:0019059 57 26 0,000 0,10874174 0,13417058 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10874174 0,13410181 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10874174 0,13403311 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10874174 0,13396448 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10874174 0,13389592 ! tube lumen formation GO:0035148 50 26 0,000 0,10874174 0,13382743 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,10874174 0,13375901 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,10874174 0,13369067 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,10874174 0,13362239 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,10874174 0,13355418 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,10874174 0,13348604 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,10874174 0,13341797 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10874174 0,13334997 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10874174 0,13328203 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10874174 0,13321417 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10874174 0,13314638 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,10874174 0,13307865 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,10874174 0,133011 ! blastocyst development GO:0001824 49 26 0,000 0,10874174 0,13294341 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10874174 0,13287589 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,10874174 0,13280844 ! neuron fate commitment GO:0048663 48 27 0,000 0,11268104 0,13754976 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,11268104 0,13748001 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,11268104 0,13741033 ! iron ion transport GO:0006826 59 27 0,000 0,11268104 0,13734072 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,11268104 0,13727118 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,11268104 0,13720171 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,11268104 0,13713231 ! fat cell differentiation GO:0045444 50 27 0,000 0,11268104 0,13706298 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,11268104 0,13699372 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,11268104 0,13692453 ! autophagy GO:0006914 41 27 0,000 0,11268104 0,13685542 ! primary neural tube formation GO:0014020 51 27 0,000 0,11268104 0,13678637 ! base-excision repair GO:0006284 41 27 0,000 0,11268104 0,13671739 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,11268104 0,13664848 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,11268104 0,13657964 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,11268104 0,13651087 ! glutathione metabolic process GO:0006749 39 27 0,000 0,11268104 0,13644216 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,11268104 0,13637353 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,11268104 0,13630497 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,11268104 0,13623647 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,11268104 0,13616805 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,11660305 0,14083682 ! circadian rhythm GO:0007623 50 28 0,000 0,11660305 0,14076615 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11660305 0,14069556 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,11660305 0,14062504 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11660305 0,14055458 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,11660305 0,1404842 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,11660305 0,14041389 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,11660305 0,14034364 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11660305 0,14027347 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11660305 0,14020337 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,11660305 0,14013334 ! synaptogenesis GO:0007416 42 28 0,000 0,11660305 0,14006338 ! lipid oxidation GO:0034440 43 28 0,000 0,11660305 0,13999349 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11660305 0,13992366 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,11660305 0,13985391 ! translational initiation GO:0006413 65 29 0,000 0,12050786 0,14446533 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,12050786 0,14439338 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12050786 0,14432151 ! regulation of pH GO:0006885 43 29 0,000 0,12050786 0,14424971 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,12050786 0,14417798 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12050786 0,14410632 ! catechol metabolic process GO:0009712 54 29 0,000 0,12050786 0,14403473 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12050786 0,14396322 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12050786 0,14389177 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,12050786 0,14382039 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12050786 0,14374909 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12050786 0,14367786 ! cell fate determination GO:0001709 60 29 0,000 0,12050786 0,14360669 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12050786 0,1435356 ! detection of light stimulus GO:0009583 38 29 0,000 0,12050786 0,14346458 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,12050786 0,14339363 ! phenol metabolic process GO:0018958 55 30 0,000 0,12439554 0,14794645 ! zinc ion transport GO:0006829 45 30 0,000 0,12439554 0,14787335 ! membrane docking GO:0022406 61 30 0,000 0,12439554 0,14780033 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12439554 0,14772738 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12439554 0,1476545 ! acute-phase response GO:0006953 49 30 0,000 0,12439554 0,14758169 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,12439554 0,14750895 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12439554 0,14743629 ! phospholipid transport GO:0015914 51 30 0,000 0,12439554 0,1473637 ! ensheathment of neurons GO:0007272 57 30 0,000 0,12439554 0,14729118 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12439554 0,14721873 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12439554 0,14714635 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,12439554 0,14707404 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12439554 0,1470018 ! eye morphogenesis GO:0048592 60 30 0,000 0,12439554 0,14692964 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12826616 0,15142708 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12826616 0,15135281 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12826616 0,15127862 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,12826616 0,1512045 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12826616 0,15113045 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12826616 0,15105648 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12826616 0,15098258 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12826616 0,15090875 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,12826616 0,15083499 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12826616 0,1507613 ! peptide transport GO:0015833 55 31 0,000 0,12826616 0,15068769 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,12826616 0,15061415 ! iron ion homeostasis GO:0055072 54 31 0,000 0,12826616 0,15054068 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,12826616 0,15046728 ! mesoderm formation GO:0001707 69 31 0,000 0,12826616 0,15039395 ! natural killer cell activation GO:0030101 45 31 0,000 0,12826616 0,15032069 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,12826616 0,15024751 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12826616 0,1501744 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12826616 0,15010135 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12826616 0,15002838 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,1321198 0,15446076 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1321198 0,15438574 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1321198 0,1543108 ! cholesterol transport GO:0030301 56 32 0,000 0,1321198 0,15423592 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1321198 0,15416113 ! spliceosome assembly GO:0000245 67 32 0,000 0,1321198 0,1540864 ! spindle organization GO:0007051 46 32 0,000 0,1321198 0,15401174 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1321198 0,15393716 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,1321198 0,15386265 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,1321198 0,15378822 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,1321198 0,15371385 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1321198 0,15363956 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1321198 0,15356533 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,1321198 0,15349118 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,1321198 0,1534171 ! peripheral nervous system development GO:0007422 64 32 0,000 0,1321198 0,1533431 ! BMP signaling pathway GO:0030509 64 32 0,000 0,1321198 0,15326916 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,1321198 0,1531953 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1321198 0,1531215 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,1321198 0,15304778 ! gene silencing GO:0016458 65 32 0,000 0,1321198 0,15297413 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,13595653 0,15734075 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,13595653 0,1572651 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13595653 0,15718953 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13595653 0,15711403 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13595653 0,15703861 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13595653 0,15696325 ! cell fate specification GO:0001708 52 33 0,000 0,13595653 0,15688797 ! sterol transport GO:0015918 57 33 0,000 0,13595653 0,15681276 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13595653 0,15673762 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13595653 0,15666256 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13595653 0,15658756 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13595653 0,15651264 ! glial cell differentiation GO:0010001 63 34 0,000 0,13977643 0,16083314 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,13977643 0,16075626 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,13977643 0,16067945 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,13977643 0,16060272 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,13977643 0,16052606 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13977643 0,16044947 ! mismatch repair GO:0006298 46 34 0,000 0,13977643 0,16037296 ! spermatid development GO:0007286 63 34 0,000 0,13977643 0,16029652 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,13977643 0,16022015 ! placenta development GO:0001890 53 34 0,000 0,13977643 0,16014385 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,14357957 0,16442286 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,14357957 0,16434464 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,14357957 0,16426649 ! odontogenesis GO:0042476 66 35 0,000 0,14357957 0,16418842 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14357957 0,16411042 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,14357957 0,16403249 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,14357957 0,16395464 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,14357957 0,16387687 ! cytokine production GO:0001816 59 35 0,000 0,14357957 0,16379916 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,14357957 0,16372153 ! neural tube formation GO:0001841 67 35 0,000 0,14357957 0,16364398 ! vesicle localization GO:0051648 64 35 0,000 0,14357957 0,16356649 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,14736601 0,16780058 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14736601 0,1677212 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,14736601 0,1676419 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,14736601 0,16756268 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14736601 0,16748353 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14736601 0,16740445 ! aerobic respiration GO:0009060 55 36 0,000 0,14736601 0,16732545 ! embryonic organ development GO:0048568 57 36 0,000 0,14736601 0,16724652 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,14736601 0,16716767 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,14736601 0,16708889 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15113585 0,17128255 ! meiosis I GO:0007127 65 37 0,000 0,15113585 0,1712019 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,15113585 0,17112134 ! sister chromatid segregation GO:0000819 58 37 0,000 0,15113585 0,17104085 ! organic anion transport GO:0015711 68 37 0,000 0,15113585 0,17096043 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,15113585 0,1708801 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15113585 0,17079983 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,15113585 0,17071964 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15113585 0,17063953 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,15113585 0,17055949 ! spermatid differentiation GO:0048515 66 37 0,000 0,15113585 0,17047953 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,15488913 0,17463133 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,15488913 0,17454953 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,15488913 0,17446782 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,15488913 0,17438618 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,15488913 0,17430461 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,15488913 0,17422312 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,15488913 0,17414171 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,15488913 0,17406037 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,15488913 0,17397911 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,15488913 0,17389793 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,15488913 0,17381682 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,15488913 0,17373578 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,15488913 0,17365483 ! glucan metabolic process GO:0044042 62 38 0,000 0,15488913 0,17357394 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,15862595 0,17767879 ! mammary gland development GO:0030879 86 39 0,000 0,15862595 0,17759611 ! learning GO:0007612 77 39 0,000 0,15862595 0,17751351 ! ear morphogenesis GO:0042471 60 39 0,000 0,15862595 0,17743098 ! organic ether metabolic process GO:0018904 55 39 0,000 0,15862595 0,17734853 ! ion transmembrane transport GO:0034220 66 39 0,000 0,15862595 0,17726616 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,15862595 0,17718386 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,15862595 0,17710164 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,15862595 0,1770195 ! RNA modification GO:0009451 57 39 0,000 0,15862595 0,17693743 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,15862595 0,17685544 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,16234637 0,18091958 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,16234637 0,18083582 ! feeding behavior GO:0007631 59 40 0,000 0,16234637 0,18075214 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,16234637 0,18066853 ! cytokinesis GO:0000910 72 40 0,000 0,16234637 0,18058501 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,16605046 0,18461987 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,16605046 0,1845346 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,16605046 0,1844494 ! gliogenesis GO:0042063 88 41 0,000 0,16605046 0,18436429 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,16605046 0,18427925 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,16605046 0,18419429 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,16605046 0,18410941 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,16605046 0,1840246 ! polyol metabolic process GO:0019751 66 41 0,000 0,16605046 0,18393988 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,16605046 0,18385523 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,16973829 0,18785204 ! regulation of tube size GO:0035150 71 42 0,000 0,16973829 0,18776567 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,16973829 0,18767938 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,16973829 0,18759317 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,16973829 0,18750704 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,16973829 0,18742099 ! neuron migration GO:0001764 79 42 0,000 0,16973829 0,18733502 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,16973829 0,18724912 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,17340994 0,19121188 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,17340994 0,19112429 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,17340994 0,19103678 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,17340994 0,19094935 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,17340994 0,190862 ! glucose transport GO:0015758 65 43 0,000 0,17340994 0,19077472 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,17340994 0,19068753 ! neural tube development GO:0021915 77 43 0,000 0,17340994 0,19060042 ! striated muscle contraction GO:0006941 77 43 0,000 0,17340994 0,19051339 ! phagocytosis GO:0006909 90 43 0,000 0,17340994 0,19042644 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,17340994 0,19033956 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17706547 0,19426335 ! hexose transport GO:0008645 67 44 0,000 0,17706547 0,19417481 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 0,000 0,17706547 0,19408635 ! biopolymer methylation GO:0043414 84 44 0,000 0,17706547 0,19399797 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,17706547 0,19390966 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,18070496 0,19780534 ! glycolysis GO:0006096 65 45 0,000 0,18070496 0,19771539 ! leukocyte migration GO:0050900 68 45 0,000 0,18070496 0,19762552 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,18070496 0,19753573 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,18070496 0,19744602 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,18070496 0,19735639 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,18070496 0,19726685 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18070496 0,19717739 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,18070496 0,197088 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,18432847 0,20094894 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,18432847 0,20085793 ! positive regulation of defense response GO:0031349 76 47 0,000 0,18793608 0,20469634 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,18793608 0,20460371 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,18793608 0,20451117 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,18793608 0,20441872 ! JNK cascade GO:0007254 91 47 0,000 0,18793608 0,20432635 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,18793608 0,20423406 ! methylation GO:0032259 90 47 0,000 0,18793608 0,20414185 ! protein homooligomerization GO:0051260 76 47 0,000 0,18793608 0,20404973 ! Notch signaling pathway GO:0007219 96 48 0,000 0,19152785 0,20785566 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,19152785 0,20776195 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,19152785 0,20766832 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,19152785 0,20757478 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,19152785 0,20748132 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,19152785 0,20738794 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,19152785 0,20729465 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,19510385 0,21107008 ! regulation of action potential GO:0001508 95 49 0,000 0,19510385 0,21097522 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,19510385 0,21088044 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,19510385 0,21078575 ! regulation of ion transport GO:0043269 77 49 0,000 0,19510385 0,21069114 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,19510385 0,21059662 ! peptide metabolic process GO:0006518 76 49 0,000 0,19510385 0,21050218 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,19510385 0,21040783 ! endocrine system development GO:0035270 104 49 0,000 0,19510385 0,21031356 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,19510385 0,21021937 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,19510385 0,21012527 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,19510385 0,21003126 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,19510385 0,20993733 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,19866415 0,21367275 ! neuromuscular process GO:0050905 99 50 0,000 0,19866415 0,21357728 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,19866415 0,21348189 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,19866415 0,21338659 ! viral infectious cycle GO:0019058 99 51 0,000 0,20220883 0,21709703 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,20220883 0,21700019 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,20220883 0,21690345 ! excretion GO:0007588 83 51 0,000 0,20220883 0,21680679 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,20220883 0,21671022 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,20220883 0,21661373 ! regulation of cell shape GO:0008360 125 51 0,000 0,20220883 0,21651733 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,20573794 0,22019816 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,20573794 0,22010025 ! membrane fusion GO:0006944 110 52 0,000 0,20573794 0,22000243 ! amino acid activation GO:0043038 92 52 0,000 0,20573794 0,2199047 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,20573794 0,21980705 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,20925155 0,22346171 ! RNA catabolic process GO:0006401 93 53 0,000 0,20925155 0,22336257 ! regulation of translational initiation GO:0006446 82 53 0,000 0,20925155 0,22326352 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,20925155 0,22316455 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,20925155 0,22306568 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,20925155 0,22296689 ! cell maturation GO:0048469 100 53 0,000 0,20925155 0,22286819 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,20925155 0,22276957 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,21274974 0,22639358 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,21274974 0,22629349 ! cell recognition GO:0008037 85 54 0,000 0,21274974 0,22619349 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,21274974 0,22609358 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,21274974 0,22599376 ! chloride transport GO:0006821 90 55 0,000 0,21623257 0,22959204 ! glucose catabolic process GO:0006007 82 55 0,000 0,21623257 0,22949076 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,21623257 0,22938958 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,21623257 0,22928848 ! gastrulation GO:0007369 112 55 0,000 0,21623257 0,22918747 ! heart morphogenesis GO:0003007 97 55 0,000 0,21623257 0,22908655 ! RNA elongation GO:0006354 79 55 0,000 0,21623257 0,22898572 ! nuclear export GO:0051168 97 55 0,000 0,21623257 0,22888498 ! regulation of actin filament length GO:0030832 105 56 0,000 0,2197001 0,23245315 ! sensory perception of smell GO:0007608 80 56 0,000 0,2197001 0,23235097 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,2197001 0,23224888 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,2197001 0,23214688 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,2197001 0,23204497 ! regulation of DNA replication GO:0006275 101 56 0,000 0,2197001 0,23194316 ! proton transport GO:0015992 94 56 0,000 0,2197001 0,23184143 ! muscle fiber development GO:0048747 112 57 0,000 0,22315241 0,23538128 ! hydrogen transport GO:0006818 97 58 0,000 0,22658956 0,23890206 ! regulation of endocytosis GO:0030100 91 58 0,000 0,22658956 0,23879741 ! adult behavior GO:0030534 99 58 0,000 0,22658956 0,23869286 ! positive regulation of secretion GO:0051047 95 59 0,000 0,23001162 0,24219167 ! regulation of cellular component size GO:0032535 109 59 0,000 0,23001162 0,24208572 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,23001162 0,24197987 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,23001162 0,24187411 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,23001162 0,24176844 ! establishment of organelle localization GO:0051656 109 59 0,000 0,23001162 0,24166286 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,23341865 0,24513543 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,23341865 0,24502848 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,23341865 0,24492162 ! regulation of heart contraction GO:0008016 110 60 0,000 0,23341865 0,24481485 ! camera-type eye development GO:0043010 116 60 0,000 0,23341865 0,24470818 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,23341865 0,2446016 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,23681071 0,24804814 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,23681071 0,2479402 ! mesoderm development GO:0007498 119 61 0,000 0,23681071 0,24783235 ! tRNA processing GO:0008033 89 61 0,000 0,23681071 0,2477246 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,23681071 0,24761694 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,24018788 0,25103912 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,24355022 0,25444283 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,24355022 0,25433239 ! detection of external stimulus GO:0009581 91 63 0,000 0,24355022 0,25422205 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,24355022 0,25411181 ! cell redox homeostasis GO:0045454 102 64 0,000 0,24689779 0,25749288 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,24689779 0,25738132 ! single fertilization GO:0007338 75 64 0,000 0,24689779 0,25726985 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,25023065 0,26062985 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,25023065 0,26051707 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,25023065 0,26040439 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,25354888 0,26374345 ! extracellular matrix organization GO:0030198 133 66 0,000 0,25354888 0,26362947 ! developmental maturation GO:0021700 116 66 0,000 0,25354888 0,26351559 ! cell projection assembly GO:0030031 120 66 0,000 0,25354888 0,26340181 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,25685253 0,26671868 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,25685253 0,26660362 ! chromosome segregation GO:0007059 113 67 0,000 0,25685253 0,26648865 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,25685253 0,26637379 ! hexose catabolic process GO:0019320 104 67 0,000 0,25685253 0,26625902 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,25685253 0,26614435 ! adaptive immune response GO:0002250 119 67 0,000 0,25685253 0,26602978 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,25685253 0,26591531 ! amino acid transport GO:0006865 125 68 0,000 0,26014167 0,26920467 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,26014167 0,26908893 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,26014167 0,26897329 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,26014167 0,26885775 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,26341636 0,27212527 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,26341636 0,27200848 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,26341636 0,27189179 ! antigen processing and presentation GO:0019882 104 69 0,000 0,26341636 0,2717752 ! amine catabolic process GO:0009310 117 71 0,000 0,26992264 0,27836857 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,26992264 0,27824931 ! regulation of immune effector process GO:0002697 137 71 0,000 0,26992264 0,27813014 ! acute inflammatory response GO:0002526 113 72 0,000 0,27315436 0,28133964 ! carbohydrate transport GO:0008643 110 72 0,000 0,27315436 0,28121926 ! learning or memory GO:0007611 147 73 0,000 0,27637189 0,28441008 ! regulation of blood pressure GO:0008217 125 73 0,000 0,27637189 0,28428848 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,27637189 0,28416699 ! axon guidance GO:0007411 139 73 0,000 0,27637189 0,2840456 ! fertilization GO:0009566 90 73 0,000 0,27637189 0,28392432 ! transition metal ion transport GO:0000041 126 74 0,000 0,27957527 0,28709266 ! neurotransmitter transport GO:0006836 123 74 0,000 0,27957527 0,28697018 ! exocytosis GO:0006887 133 74 0,000 0,27957527 0,28684781 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,27957527 0,28672554 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,27957527 0,28660337 ! eye development GO:0001654 143 74 0,000 0,27957527 0,28648131 ! organelle localization GO:0051640 136 74 0,000 0,27957527 0,28635935 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,28276459 0,2895028 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,28276459 0,28937966 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,28276459 0,28925663 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,28593988 0,29238052 ! defense response to bacterium GO:0042742 89 76 0,000 0,28593988 0,29225631 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,28593988 0,29213221 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,28593988 0,29200822 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,28910123 0,29511139 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,28910123 0,29498624 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,29224868 0,29807136 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,29224868 0,29794506 ! protein oligomerization GO:0051259 139 78 0,000 0,29224868 0,29781886 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,29538231 0,30088477 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,29538231 0,30075744 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,29850216 0,3038055 ! protein import into nucleus GO:0006606 158 80 0,000 0,29850216 0,30367704 ! inorganic anion transport GO:0015698 138 80 0,000 0,29850216 0,30354869 ! digestion GO:0007586 112 81 0,000 0,3016083 0,30657777 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,3016083 0,3064483 ! nuclear import GO:0051170 161 81 0,000 0,3016083 0,30631894 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,3047008 0,30932916 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,31084507 0,31543367 ! response to unfolded protein GO:0006986 131 85 0,000 0,31389696 0,31839633 ! nucleosome assembly GO:0006334 122 85 0,000 0,31389696 0,31826215 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,31389696 0,31812809 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,31693545 0,32107229 ! chromatin assembly GO:0031497 124 86 0,000 0,31693545 0,32093716 ! alcohol catabolic process GO:0046164 130 86 0,000 0,31693545 0,32080214 ! amine transport GO:0015837 155 86 0,000 0,31693545 0,32066723 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,31996057 0,3235919 ! protein localization in nucleus GO:0034504 176 87 0,000 0,31996057 0,32345594 ! cellular respiration GO:0045333 135 88 0,000 0,3229724 0,32636354 ! regulation of neurological system process GO:0031644 148 88 0,000 0,3229724 0,32622653 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,3229724 0,32608963 ! cellular defense response GO:0006968 114 89 0,000 0,32597099 0,32897911 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,32597099 0,32884118 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,3289564 0,33171379 ! sterol metabolic process GO:0016125 152 91 0,000 0,33192869 0,33457077 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,33192869 0,33443066 ! regulation of defense response GO:0031347 149 92 0,000 0,3348879 0,33727095 ! nucleosome organization GO:0034728 138 92 0,000 0,3348879 0,33712983 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,3348879 0,33698883 ! vitamin metabolic process GO:0006766 139 92 0,000 0,3348879 0,33684795 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,33783411 0,3396694 ! transcription initiation GO:0006352 153 94 0,000 0,34076737 0,34247548 ! regulation of T cell activation GO:0050863 158 94 0,000 0,34076737 0,34233248 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,34368773 0,34512215 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,34659525 0,3478966 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,34659525 0,34775153 ! positive regulation of immune response GO:0050778 156 96 0,000 0,34659525 0,34760657 ! detection of stimulus GO:0051606 151 96 0,000 0,34659525 0,34746173 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,34948998 0,35021778 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,34948998 0,35007198 ! protein ubiquitination GO:0016567 217 97 0,000 0,34948998 0,3499263 ! hormone metabolic process GO:0042445 157 97 0,000 0,34948998 0,34978074 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,35237199 0,3525185 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,35237199 0,35237199 GO:0016054|organic acid catabolic process,