pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1214-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phosphoinositide 3-kinase cascade GO:0014065 23 8 3,000 9,292E-09 2,137E-05 ! insulin receptor signaling pathway GO:0008286 40 24 4,000 1,767E-08 2,032E-05 ! positive regulation of cell migration GO:0030335 92 51 5,000 2,235E-08 1,714E-05 ! positive regulation of cell motion GO:0051272 99 56 5,000 3,976E-08 2,286E-05 ! cellular response to insulin stimulus GO:0032869 52 34 4,000 1,126E-07 5,182E-05 ! response to insulin stimulus GO:0032868 63 43 4,000 3,804E-07 1,458E-04 ! positive regulation of glycolysis GO:0045821 11 5 2,000 4,022E-07 1,322E-04 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 3,000 4,999E-07 1,437E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 3,000 6,233E-07 1,593E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 3,000 1,353E-06 3,111E-04 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 1,594E-06 3,333E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 2,236E-06 4,285E-04 ! positive regulation of glucose metabolic process GO:0010907 15 9 2,000 3,345E-06 5,918E-04 ! regulation of glycolysis GO:0006110 15 9 2,000 3,345E-06 5,496E-04 ! mammary gland development GO:0030879 57 31 3,000 3,933E-06 6,031E-04 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 3,000 4,484E-06 6,445E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 2,000 4,767E-06 6,449E-04 GO:0043470|regulation of carbohydrate catabolic process, ! cellular response to hormone stimulus GO:0032870 109 74 4,000 5,861E-06 7,489E-04 ! positive regulation of cellular catabolic process GO:0031331 22 12 2,000 8,696E-06 1,053E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 2,000 8,696E-06 1E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 1,007E-05 1,103E-03 ! regulation of gene-specific transcription GO:0032583 69 43 3,000 1,495E-05 1,563E-03 ! positive regulation of cell cycle GO:0045787 77 45 3,000 1,796E-05 1,796E-03 ! regulation of glucose metabolic process GO:0010906 22 16 2,000 2,192E-05 2,1E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 2,000 2,192E-05 2,016E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 2,655E-05 2,348E-03 ! positive regulation of organelle organization GO:0010638 82 51 3,000 2,965E-05 2,526E-03 ! positive regulation of DNA replication GO:0045740 29 18 2,000 3,178E-05 2,61E-03 ! regulation of mitosis GO:0007088 84 54 3,000 3,723E-05 2,953E-03 GO:0051783|regulation of nuclear division, ! regulation of carbohydrate metabolic process GO:0006109 28 19 2,000 3,764E-05 2,886E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! vasculogenesis GO:0001570 33 22 2,000 5,938E-05 4,405E-03 ! interaction with host GO:0051701 37 23 2,000 6,811E-05 4,896E-03 ! regulation of cellular catabolic process GO:0031329 36 24 2,000 7,765E-05 5,412E-03 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 7,765E-05 5,253E-03 ! positive regulation of nuclear division GO:0051785 39 25 2,000 8,802E-05 5,784E-03 GO:0045840|positive regulation of mitosis, ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 2,000 9,925E-05 6,341E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,19E-04 7,395E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 1,19E-04 7,2E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,19E-04 7,015E-03 ! regulation of muscle cell apoptosis GO:0010660 8 5 1,000 1,19E-04 6,84E-03 ! somatic stem cell maintenance GO:0035019 13 5 1,000 1,19E-04 6,673E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,19E-04 6,514E-03 ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 1,19E-04 6,363E-03 ! positive regulation of catabolic process GO:0009896 40 28 2,000 1,244E-04 6,505E-03 ! gland development GO:0048732 148 77 3,000 1,501E-04 7,67E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 1,000 1,78E-04 8,902E-03 ! mRNA stabilization GO:0048255 15 6 1,000 1,78E-04 8,712E-03 GO:0043489|RNA stabilization, ! male sex determination GO:0030238 9 6 1,000 1,78E-04 8,531E-03 ! interaction with symbiont GO:0051702 8 6 1,000 1,78E-04 8,357E-03 ! gas homeostasis GO:0033483 11 6 1,000 1,78E-04 8,19E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,78E-04 8,029E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 1,78E-04 7,875E-03 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 1,78E-04 7,726E-03 ! regulation of cell cycle process GO:0010564 122 81 3,000 1,826E-04 7,777E-03 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 2,047E-04 8,56E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 2,199E-04 9,032E-03 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 2,000 2,239E-04 9,036E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,487E-04 9,862E-03 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 2,487E-04 9,695E-03 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 2,487E-04 9,533E-03 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 2,487E-04 9,377E-03 ! T-helper 1 type immune response GO:0042088 11 7 1,000 2,487E-04 9,225E-03 ! regulation of granule cell precursor proliferation GO:0021936 11 7 1,000 2,487E-04 9,079E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! vesicle fusion GO:0006906 15 7 1,000 2,487E-04 8,937E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 2,487E-04 8,8E-03 ! protein heterooligomerization GO:0051291 10 7 1,000 2,487E-04 8,666E-03 ! muscle adaptation GO:0043500 12 7 1,000 2,487E-04 8,537E-03 ! tissue remodeling GO:0048771 62 36 2,000 2,659E-04 8,993E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 1,000 3,308E-04 0,01102793 GO:0046579|positive regulation of Ras protein signal transduction, ! induction of positive chemotaxis GO:0050930 14 8 1,000 3,308E-04 0,01087039 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 3,308E-04 0,01071728 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 3,308E-04 0,01056843 ! multicellular organism growth GO:0035264 14 8 1,000 3,308E-04 0,01042366 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,308E-04 0,0102828 ! induction of an organ GO:0001759 11 8 1,000 3,308E-04 0,01014569 ! regulation of embryonic development GO:0045995 16 8 1,000 3,308E-04 0,0100122 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 3,308E-04 9,882E-03 ! regulation of JAK-STAT cascade GO:0046425 61 42 2,000 4,212E-04 0,01241946 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 1,000 4,244E-04 0,01235616 ! regulation of developmental growth GO:0048638 13 9 1,000 4,244E-04 0,01220171 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 4,244E-04 0,01205107 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 1,000 4,244E-04 0,0119041 GO:0010469|regulation of receptor activity, ! lung alveolus development GO:0048286 17 9 1,000 4,244E-04 0,01176068 ! positive regulation of protein polymerization GO:0032273 15 9 1,000 4,244E-04 0,01162067 ! localization within membrane GO:0051668 15 9 1,000 4,244E-04 0,01148396 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 5,167E-04 0,01382002 ! blood vessel remodeling GO:0001974 21 10 1,000 5,293E-04 0,01399344 ! pathogenesis GO:0009405 13 10 1,000 5,293E-04 0,01383443 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 5,293E-04 0,01367898 ! regulation of bone resorption GO:0045124 24 10 1,000 5,293E-04 0,013527 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 5,293E-04 0,01337835 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 5,293E-04 0,01323293 ! developmental induction GO:0031128 13 10 1,000 5,293E-04 0,01309064 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of DNA replication GO:0006275 75 48 2,000 6,252E-04 0,01529725 ! virus-host interaction GO:0019048 17 11 1,000 6,455E-04 0,01562766 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 6,455E-04 0,01546487 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 6,455E-04 0,01530544 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 6,455E-04 0,01514926 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 1,000 6,455E-04 0,01499624 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 6,455E-04 0,01484628 ! stem cell development GO:0048864 29 11 1,000 6,455E-04 0,01469928 GO:0019827|stem cell maintenance, ! regulation of leukocyte migration GO:0002685 24 11 1,000 6,455E-04 0,01455517 ! gland morphogenesis GO:0022612 23 12 1,000 7,728E-04 0,0172578 ! regulation of mRNA stability GO:0043488 27 12 1,000 7,728E-04 0,01709186 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 7,728E-04 0,01692908 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 9,113E-04 0,01977386 ! lipid localization GO:0010876 24 13 1,000 9,113E-04 0,01958905 GO:0019915|lipid storage, ! regulation of monooxygenase activity GO:0032768 26 13 1,000 9,113E-04 0,01940767 ! tissue regeneration GO:0042246 21 13 1,000 9,113E-04 0,01922962 ! regulation of RNA stability GO:0043487 28 13 1,000 9,113E-04 0,01905481 ! organelle fusion GO:0048284 28 13 1,000 9,113E-04 0,01888314 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 9,823E-04 0,02017276 ! myotube differentiation GO:0014902 21 14 1,000 1,061E-03 0,02159185 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,061E-03 0,02140245 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,061E-03 0,02121634 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 1,061E-03 0,02103344 ! water homeostasis GO:0030104 24 14 1,000 1,061E-03 0,02085367 ! cell killing GO:0001906 20 14 1,000 1,061E-03 0,02067694 ! activation of MAPK activity GO:0000187 84 59 2,000 1,144E-03 0,02210151 ! lung development GO:0030324 94 59 2,000 1,144E-03 0,02191733 ! lipid phosphorylation GO:0046834 23 15 1,000 1,221E-03 0,02321428 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 1,000 1,221E-03 0,023024 ! myoblast differentiation GO:0045445 27 15 1,000 1,221E-03 0,02283681 ! regulation of vasodilation GO:0042312 24 15 1,000 1,221E-03 0,02265265 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,221E-03 0,02247143 ! respiratory tube development GO:0030323 99 62 2,000 1,32E-03 0,0241042 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 1,383E-03 0,02504809 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 1,000 1,393E-03 0,02502346 ! complement activation, alternative pathway GO:0006957 16 16 1,000 1,393E-03 0,02482948 ! respiratory system development GO:0060541 100 64 2,000 1,448E-03 0,02561009 ! adaptive immune response GO:0002250 94 64 2,000 1,448E-03 0,02541459 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! protein oligomerization GO:0051259 100 65 2,000 1,514E-03 0,02637717 ! inactivation of MAPK activity GO:0000188 27 17 1,000 1,575E-03 0,02723255 ! stem cell differentiation GO:0048863 36 17 1,000 1,575E-03 0,02702932 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,575E-03 0,0268291 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 1,768E-03 0,02989363 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 1,874E-03 0,03145836 ! regulation of catabolic process GO:0009894 106 70 2,000 1,874E-03 0,0312304 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 1,971E-03 0,03261617 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 1,971E-03 0,03238319 ! regeneration GO:0031099 32 19 1,000 1,971E-03 0,03215353 ! sex determination GO:0007530 29 19 1,000 1,971E-03 0,03192709 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 1,971E-03 0,03170383 ! cytolysis GO:0019835 20 19 1,000 1,971E-03 0,03148366 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 1,971E-03 0,03126653 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 1,971E-03 0,03105238 ! regulation of peptidase activity GO:0052547 106 72 2,000 2,031E-03 0,03178528 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 2,031E-03 0,03157051 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 2,000 2,031E-03 0,03135863 ! positive regulation of locomotion GO:0040017 35 20 1,000 2,185E-03 0,03350731 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to oxygen levels GO:0070482 137 74 2,000 2,197E-03 0,03346717 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 2,41E-03 0,03646522 ! regulation of chemotaxis GO:0050920 36 21 1,000 2,41E-03 0,03622689 ! vesicle docking GO:0048278 27 21 1,000 2,41E-03 0,03599165 ! regulation of vasoconstriction GO:0019229 31 21 1,000 2,41E-03 0,03575944 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 2,645E-03 0,0389957 ! regulation of behavior GO:0050795 38 22 1,000 2,645E-03 0,03874732 ! membrane depolarization GO:0051899 35 22 1,000 2,645E-03 0,03850208 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 2,645E-03 0,03825993 ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 2,645E-03 0,0380208 ! proteoglycan biosynthetic process GO:0030166 32 22 1,000 2,645E-03 0,03778465 ! regulation of blood coagulation GO:0030193 34 22 1,000 2,645E-03 0,03755141 ! protein tetramerization GO:0051262 39 22 1,000 2,645E-03 0,03732103 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,89E-03 0,0405352 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 3,146E-03 0,04385382 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 3,258E-03 0,04514262 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 3,258E-03 0,0448723 ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 3,412E-03 0,04671121 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 3,412E-03 0,04643481 ! skeletal muscle tissue development GO:0007519 123 87 2,000 3,479E-03 0,04707219 GO:0060538|skeletal muscle organ development, ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 3,688E-03 0,04960477 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 3,688E-03 0,04931637 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 3,688E-03 0,04903131 ! regulation of coagulation GO:0050818 39 26 1,000 3,688E-03 0,04874952 ! proteoglycan metabolic process GO:0006029 41 27 1,000 3,974E-03 0,05223151 ! membrane docking GO:0022406 39 27 1,000 3,974E-03 0,05193474 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 4,197E-03 0,05453727 ! cholesterol homeostasis GO:0042632 46 28 1,000 4,27E-03 0,05517761 GO:0055092|sterol homeostasis, ! complement activation, classical pathway GO:0006958 36 28 1,000 4,27E-03 0,05486935 ! triglyceride metabolic process GO:0006641 34 28 1,000 4,27E-03 0,05456452 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 4,27E-03 0,05426306 ! angiogenesis GO:0001525 149 95 2,000 4,455E-03 0,05629605 ! regulation of response to external stimulus GO:0032101 139 96 2,000 4,587E-03 0,05765234 ! cholesterol transport GO:0030301 46 30 1,000 4,892E-03 0,06115308 GO:0015918|sterol transport, ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 1,000 4,892E-03 0,06082252 ! regulation of microtubule-based process GO:0032886 58 30 1,000 4,892E-03 0,06049552 ! glial cell differentiation GO:0010001 55 31 1,000 5,218E-03 0,06417805 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 1,000 5,218E-03 0,06383668 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 5,218E-03 0,06349892 ! cell fate specification GO:0001708 37 31 1,000 5,218E-03 0,06316471 ! leukocyte chemotaxis GO:0030595 43 31 1,000 5,218E-03 0,06283401 GO:0060326|cell chemotaxis, ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 5,553E-03 0,06652489 ! neutral lipid metabolic process GO:0006638 41 32 1,000 5,553E-03 0,0661802 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 50 32 1,000 5,553E-03 0,06583906 ! carbohydrate homeostasis GO:0033500 39 33 1,000 5,898E-03 0,06957156 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 55 33 1,000 5,898E-03 0,06921661 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 6,253E-03 0,07300592 ! glycerol ether metabolic process GO:0006662 44 34 1,000 6,253E-03 0,0726372 ! protein homooligomerization GO:0051260 52 35 1,000 6,617E-03 0,07648118 ! organic ether metabolic process GO:0018904 46 36 1,000 6,991E-03 0,08039531 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 7,374E-03 0,08437777 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 1,000 7,374E-03 0,08396006 GO:0006956|complement activation, ! gliogenesis GO:0042063 71 38 1,000 7,766E-03 0,08799117 ! developmental growth GO:0048589 62 39 1,000 8,168E-03 0,09208694 ! cell growth GO:0016049 61 39 1,000 8,168E-03 0,09163774 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 8,578E-03 0,09577846 ! ATP synthesis coupled electron transport GO:0042773 48 40 1,000 8,578E-03 0,09531576 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! receptor-mediated endocytosis GO:0006898 76 42 1,000 9,427E-03 0,10424179 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 9,427E-03 0,10374302 ! excretion GO:0007588 63 42 1,000 9,427E-03 0,10324901 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 9,427E-03 0,10275968 ! regulation of cell shape GO:0008360 78 42 1,000 9,427E-03 0,10227496 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 9,865E-03 0,1065225 ! leukocyte migration GO:0050900 60 43 1,000 9,865E-03 0,10602473 ! activation of caspase activity GO:0006919 65 43 1,000 9,865E-03 0,10553159 ! vesicle organization GO:0016050 79 43 1,000 9,865E-03 0,10504302 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,01076722 0,11412261 ! response to UV GO:0009411 75 46 1,000 0,01123157 0,11849826 ! respiratory electron transport chain GO:0022904 59 47 1,000 0,01170464 0,12292545 ! regulation of protein polymerization GO:0032271 71 47 1,000 0,01170464 0,1223667 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,01218636 0,12682633 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 1,000 0,01218636 0,12625504 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,01218636 0,12568887 ! heart morphogenesis GO:0003007 65 48 1,000 0,01218636 0,12512776 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,01218636 0,12457164 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,01218636 0,12402044 ! sulfur compound biosynthetic process GO:0044272 62 49 1,000 0,01267666 0,12844188 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,01267666 0,12787854 ! regulation of actin filament length GO:0030832 72 50 1,000 0,01317548 0,13233011 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,01317548 0,13175476 ! membrane fusion GO:0006944 80 50 1,000 0,01317548 0,13118439 ! lipid modification GO:0030258 73 50 1,000 0,01317548 0,13061894 ! positive regulation of growth GO:0045927 67 50 1,000 0,01317548 0,13005834 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,01368275 0,1344886 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01368275 0,13391631 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,01368275 0,13334887 ! regulation of cellular component size GO:0032535 74 52 1,000 0,01419842 0,13779062 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01419842 0,13721167 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,01472243 0,14168027 ! regulation of protein complex assembly GO:0043254 81 54 1,000 0,0152547 0,14619087 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,0152547 0,14558427 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,0152547 0,14498269 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,0152547 0,14438605 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,01690051 0,1593081 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01732716 0,1626631 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01732716 0,16200187 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01732716 0,16134599 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01732716 0,1606954 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01732716 0,16005004 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01732716 0,15940984 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01732716 0,15877474 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01732716 0,15814468 ! sleep GO:0030431 11 5 0,000 0,01732716 0,15751961 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01732716 0,15689945 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01732716 0,15628416 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01732716 0,15567367 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01732716 0,15506794 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01732716 0,1544669 ! tongue development GO:0043586 6 5 0,000 0,01732716 0,1538705 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01732716 0,15327869 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01732716 0,15269142 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01732716 0,15210863 ! cobalt ion transport GO:0006824 9 5 0,000 0,01732716 0,15153027 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01732716 0,15095629 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01732716 0,15038664 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01732716 0,14982128 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01732716 0,14926015 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01732716 0,14870321 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01732716 0,14815041 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01732716 0,14760171 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01732716 0,14705705 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01732716 0,1465164 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01732716 0,14597971 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01732716 0,14544694 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01732716 0,14491804 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01732716 0,14439297 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01732716 0,1438717 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01732716 0,14335417 ! malate metabolic process GO:0006108 7 5 0,000 0,01732716 0,14284036 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01732716 0,14233022 ! behavioral response to pain GO:0048266 7 5 0,000 0,01732716 0,1418237 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01732716 0,14132078 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01732716 0,14082141 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01732716 0,14032556 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01732716 0,13983319 ! mating behavior GO:0007617 6 5 0,000 0,01732716 0,13934427 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01732716 0,13885875 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01732716 0,1383766 ! rhythmic behavior GO:0007622 12 5 0,000 0,01732716 0,13789779 ! copulation GO:0007620 7 5 0,000 0,01732716 0,13742228 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01732716 0,13695004 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01732716 0,13648103 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01732716 0,13601522 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01732716 0,13555259 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01732716 0,13509309 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01732716 0,13463669 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01732716 0,13418337 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01732716 0,13373309 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01732716 0,13328582 ! response to protozoan GO:0001562 9 5 0,000 0,01732716 0,13284153 ! lymph vessel development GO:0001945 7 5 0,000 0,01732716 0,1324002 ! endochondral ossification GO:0001958 12 5 0,000 0,01732716 0,13196179 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01732716 0,13152627 ! parathyroid gland development GO:0060017 8 5 0,000 0,01732716 0,13109362 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01732716 0,1306638 ! anagen GO:0042640 6 5 0,000 0,01732716 0,1302368 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01732716 0,12981257 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01732716 0,12939111 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01732716 0,12897236 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01732716 0,12855632 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01732716 0,12814296 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01732716 0,12773224 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01732716 0,12732415 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01732716 0,12691866 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01732716 0,12651575 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01732716 0,12611538 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01732716 0,12571754 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01732716 0,1253222 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01732716 0,12492934 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01732716 0,12453894 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01732716 0,12415097 ! ovulation GO:0030728 6 5 0,000 0,01732716 0,1237654 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01732716 0,12338223 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01732716 0,12300142 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01732716 0,12262296 ! response to pH GO:0009268 9 5 0,000 0,01732716 0,12224681 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01732716 0,12187297 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01732716 0,1215014 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01732716 0,1211321 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01732716 0,12076503 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01732716 0,12040018 ! polyol catabolic process GO:0046174 7 5 0,000 0,01732716 0,12003753 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01732716 0,11967706 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01732716 0,11931874 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01732716 0,11896257 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01732716 0,11860851 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01732716 0,11825656 ! urea metabolic process GO:0019627 6 5 0,000 0,01732716 0,11790669 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01732716 0,11755888 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01732716 0,11721312 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01732716 0,11686939 ! neutrophil activation GO:0042119 5 5 0,000 0,01732716 0,11652766 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01732716 0,11618793 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01732716 0,11585018 ! response to food GO:0032094 5 5 0,000 0,01732716 0,11551438 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01732716 0,11518052 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01732716 0,11484859 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01732716 0,11451856 ! forebrain neuron development GO:0021884 7 5 0,000 0,01732716 0,11419043 ! melanosome organization GO:0032438 7 5 0,000 0,01732716 0,11386417 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01732716 0,11353977 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01732716 0,11321722 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01732716 0,11289649 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01732716 0,11257757 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01732716 0,11226045 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01732716 0,11194511 ! nucleoside transport GO:0015858 6 5 0,000 0,01732716 0,11163154 ! nucleoside salvage GO:0043174 7 5 0,000 0,01732716 0,11131972 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01732716 0,11100964 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01732716 0,11070128 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01732716 0,11039463 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01732716 0,11008967 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01732716 0,10978639 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01732716 0,10948478 ! depyrimidination GO:0045008 8 5 0,000 0,01732716 0,10918482 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01732716 0,1088865 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01732716 0,10858981 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01732716 0,10829473 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01732716 0,10800125 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01732716 0,10770935 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01732716 0,10741903 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01732716 0,10713027 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01732716 0,10684306 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01732716 0,10655738 ! monocyte differentiation GO:0030224 8 5 0,000 0,01732716 0,10627323 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01732716 0,10599059 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01732716 0,10570944 ! centrosome duplication GO:0051298 5 5 0,000 0,01732716 0,10542979 ! response to UV-C GO:0010225 6 5 0,000 0,01732716 0,10515161 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01732716 0,1048749 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01732716 0,10459963 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01732716 0,10432581 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01732716 0,10405342 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01732716 0,10378245 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01732716 0,10351288 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01732716 0,10324472 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01732716 0,10297793 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01732716 0,10271253 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01732716 0,10244848 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01732716 0,1021858 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01732716 0,10192445 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01732716 0,10166444 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01732716 0,10140575 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01732716 0,10114838 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01732716 0,1008923 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01732716 0,10063753 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01732716 0,10038403 ! neural tube patterning GO:0021532 6 5 0,000 0,01732716 0,10013181 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01732716 0,09988085 ! histone demethylation GO:0016577 9 5 0,000 0,01732716 0,09963115 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01732716 0,09938269 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01732716 0,09913547 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01732716 0,09888948 ! enteric nervous system development GO:0048484 8 5 0,000 0,01732716 0,0986447 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01732716 0,09840114 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01732716 0,09815877 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01732716 0,09791759 ! transcription termination GO:0006353 8 5 0,000 0,01732716 0,0976776 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01732716 0,09743878 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01732716 0,09720112 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01732716 0,09696462 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01732716 0,09672927 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01732716 0,09649506 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01732716 0,09626198 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01732716 0,09603003 ! apical protein localization GO:0045176 6 5 0,000 0,01732716 0,09579918 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01732716 0,09556945 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01732716 0,09534081 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01732716 0,09511327 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01732716 0,09488681 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01732716 0,09466143 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01732716 0,09443711 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01732716 0,09421385 ! glial cell migration GO:0008347 10 5 0,000 0,01732716 0,09399165 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01732716 0,0937705 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01732716 0,09355038 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01732716 0,09333129 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01732716 0,09311323 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01732716 0,09289618 ! neural plate development GO:0001840 6 5 0,000 0,01732716 0,09268014 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01732716 0,09246511 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01732716 0,09225107 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01732716 0,09203801 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01732716 0,09182595 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01732716 0,09161485 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01732716 0,09140473 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01732716 0,09119556 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01732716 0,09098735 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01732716 0,09078009 ! spindle assembly GO:0051225 5 5 0,000 0,01732716 0,09057377 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01732716 0,09036839 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01732716 0,09016394 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01732716 0,08996041 ! organ regeneration GO:0031100 7 5 0,000 0,01732716 0,08975779 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01732716 0,08955609 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01732716 0,08935529 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01732716 0,08915539 GO:0055081|anion homeostasis, ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,01746524 0,0896653 ! viral reproductive process GO:0022415 87 58 1,000 0,01746524 0,0894656 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,01746524 0,08926679 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,01861853 0,09495036 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,01861853 0,09474029 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,01920696 0,09751879 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,01980318 0,10032447 ! viral reproduction GO:0016032 92 63 1,000 0,02040711 0,10315684 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02040711 0,10293062 ! tRNA transcription GO:0009304 11 6 0,000 0,02075698 0,10446621 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02075698 0,10423812 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02075698 0,10401102 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02075698 0,10378491 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02075698 0,10355978 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02075698 0,10333562 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02075698 0,10311243 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02075698 0,10289021 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02075698 0,10266894 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02075698 0,10244862 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02075698 0,10222924 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02075698 0,10201081 ! prostate gland development GO:0030850 9 6 0,000 0,02075698 0,1017933 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02075698 0,10157672 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02075698 0,10136105 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02075698 0,10114631 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02075698 0,10093247 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02075698 0,10071953 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02075698 0,10050749 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02075698 0,10029634 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02075698 0,10008607 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02075698 0,09987669 ! neuron adhesion GO:0007158 9 6 0,000 0,02075698 0,09966818 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,02075698 0,09946054 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02075698 0,09925376 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02075698 0,09904784 ! signal peptide processing GO:0006465 8 6 0,000 0,02075698 0,09884277 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02075698 0,09863855 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02075698 0,09843517 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02075698 0,09823263 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02075698 0,09803092 ! opsonization GO:0008228 8 6 0,000 0,02075698 0,09783003 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02075698 0,09762997 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02075698 0,09743073 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02075698 0,09723229 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02075698 0,09703467 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02075698 0,09683784 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02075698 0,09664182 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02075698 0,09644658 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02075698 0,09625213 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02075698 0,09605846 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02075698 0,09586558 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02075698 0,09567346 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02075698 0,09548211 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02075698 0,09529153 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02075698 0,09510171 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02075698 0,09491264 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02075698 0,09472432 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02075698 0,09453675 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02075698 0,09434991 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02075698 0,09416382 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02075698 0,09397846 ! thymic T cell selection GO:0045061 12 6 0,000 0,02075698 0,09379382 ! protein lipoylation GO:0009249 10 6 0,000 0,02075698 0,09360992 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02075698 0,09342673 ! pigment granule organization GO:0048753 11 6 0,000 0,02075698 0,09324425 ! drug transport GO:0015893 6 6 0,000 0,02075698 0,09306249 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02075698 0,09288143 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02075698 0,09270108 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02075698 0,09252143 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02075698 0,09234247 ! histidine metabolic process GO:0006547 6 6 0,000 0,02075698 0,0921642 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02075698 0,09198662 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02075698 0,09180972 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02075698 0,09163351 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02075698 0,09145796 ! adenohypophysis development GO:0021984 10 6 0,000 0,02075698 0,09128309 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02075698 0,09110889 ! hyperosmotic response GO:0006972 8 6 0,000 0,02075698 0,09093535 ! microtubule nucleation GO:0007020 10 6 0,000 0,02075698 0,09076247 ! ER overload response GO:0006983 7 6 0,000 0,02075698 0,09059024 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02075698 0,09041867 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02075698 0,09024774 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02075698 0,09007747 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02075698 0,08990783 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02075698 0,08973883 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02075698 0,08957046 ! response to dietary excess GO:0002021 7 6 0,000 0,02075698 0,08940273 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02075698 0,08923562 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02075698 0,08906914 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02075698 0,08890327 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02075698 0,08873802 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02075698 0,08857339 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02075698 0,08840936 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02075698 0,08824595 ! neuron apoptosis GO:0051402 8 6 0,000 0,02075698 0,08808313 ! organic alcohol transport GO:0015850 9 6 0,000 0,02075698 0,08792091 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02075698 0,0877593 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02075698 0,08759827 ! carnitine transport GO:0015879 8 6 0,000 0,02075698 0,08743783 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02075698 0,08727798 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02075698 0,08711872 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02075698 0,08696003 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02075698 0,08680192 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02075698 0,08664439 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02075698 0,08648742 ! parturition GO:0007567 12 6 0,000 0,02075698 0,08633103 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02075698 0,08617519 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02075698 0,08601992 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02075698 0,08586521 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02075698 0,08571105 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02075698 0,08555745 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02075698 0,0854044 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02075698 0,08525189 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02075698 0,08509992 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02075698 0,0849485 ! macrophage differentiation GO:0030225 10 6 0,000 0,02075698 0,08479761 ! astrocyte development GO:0014002 14 6 0,000 0,02075698 0,08464726 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02075698 0,08449745 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02075698 0,08434816 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02075698 0,08419939 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02075698 0,08405116 ! eating behavior GO:0042755 6 6 0,000 0,02075698 0,08390344 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02075698 0,08375624 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02075698 0,08360956 ! response to copper ion GO:0046688 9 6 0,000 0,02075698 0,08346339 ! DNA topological change GO:0006265 8 6 0,000 0,02075698 0,08331773 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02075698 0,08317257 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02075698 0,08302792 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02075698 0,08288378 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02075698 0,08274013 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02075698 0,08259698 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02075698 0,08245433 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02075698 0,08231217 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02075698 0,08217049 ! hair follicle maturation GO:0048820 7 6 0,000 0,02075698 0,08202931 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02075698 0,08188861 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02075698 0,08174839 ! Schwann cell development GO:0014044 14 6 0,000 0,02075698 0,08160864 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02075698 0,08146938 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02075698 0,08133059 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02075698 0,08119227 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02075698 0,08105443 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02075698 0,08091705 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02075698 0,08078013 ! histone ubiquitination GO:0016574 7 6 0,000 0,02075698 0,08064368 ! regulation of meiosis GO:0040020 10 6 0,000 0,02075698 0,08050768 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02075698 0,08037215 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02075698 0,08023707 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02075698 0,08010244 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02075698 0,07996827 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02075698 0,07983454 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02075698 0,07970126 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02075698 0,07956843 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02075698 0,07943603 ! receptor internalization GO:0031623 9 6 0,000 0,02075698 0,07930408 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02075698 0,07917257 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02075698 0,07904148 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02075698 0,07891084 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02075698 0,07878062 ! protein deubiquitination GO:0016579 8 6 0,000 0,02075698 0,07865083 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02075698 0,07852148 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02075698 0,07839254 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02075698 0,07826403 ! axonal fasciculation GO:0007413 9 6 0,000 0,02075698 0,07813594 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02075698 0,07800826 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02075698 0,07788101 ! midbrain development GO:0030901 6 6 0,000 0,02075698 0,07775416 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02075698 0,07762773 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02075698 0,07750172 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02075698 0,07737611 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02075698 0,0772509 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02075698 0,0771261 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02075698 0,0770017 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02075698 0,07687771 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02075698 0,07675411 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02075698 0,07663091 ! adult feeding behavior GO:0008343 6 6 0,000 0,02075698 0,0765081 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02075698 0,07638569 ! blastocyst growth GO:0001832 15 6 0,000 0,02075698 0,07626367 ! pigment granule transport GO:0051904 12 6 0,000 0,02075698 0,07614204 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02075698 0,07602079 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02075698 0,07589993 ! catecholamine transport GO:0051937 7 6 0,000 0,02075698 0,07577946 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02075698 0,07565936 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02075698 0,07553965 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02075698 0,07542031 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02075698 0,07530135 ! protein prenylation GO:0018342 10 6 0,000 0,02075698 0,07518277 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02075698 0,07506455 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02075698 0,07494671 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,02101871 0,0757728 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,02101871 0,07565421 ! regulation of caspase activity GO:0043281 97 65 1,000 0,02163792 0,07776127 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,02163792 0,07763995 ! activation of immune response GO:0002253 83 65 1,000 0,02163792 0,07751902 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,02226467 0,07964033 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,0228989 0,08178178 ! acute inflammatory response GO:0002526 92 68 1,000 0,02354056 0,08394309 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,02354056 0,08381315 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02417503 0,08593906 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02417503 0,08580643 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02417503 0,08567422 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02417503 0,08554241 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02417503 0,08541101 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02417503 0,08528001 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02417503 0,08514942 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02417503 0,08501922 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02417503 0,08488942 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02417503 0,08476001 ! reproductive behavior GO:0019098 12 7 0,000 0,02417503 0,084631 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02417503 0,08450239 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02417503 0,08437416 ! oligopeptide transport GO:0006857 11 7 0,000 0,02417503 0,08424632 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02417503 0,08411886 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02417503 0,0839918 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,02417503 0,08386511 ! pericardium development GO:0060039 8 7 0,000 0,02417503 0,08373881 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02417503 0,08361289 ! fibril organization GO:0043206 13 7 0,000 0,02417503 0,08348734 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02417503 0,08336217 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02417503 0,08323738 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02417503 0,08311296 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02417503 0,08298891 ! lipoprotein transport GO:0042953 9 7 0,000 0,02417503 0,08286523 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02417503 0,08274192 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02417503 0,08261897 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02417503 0,08249639 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02417503 0,08237418 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02417503 0,08225232 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02417503 0,08213083 ! chemosensory behavior GO:0007635 9 7 0,000 0,02417503 0,08200969 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02417503 0,08188891 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02417503 0,08176848 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02417503 0,08164841 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02417503 0,08152869 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02417503 0,08140933 ! reflex GO:0060004 12 7 0,000 0,02417503 0,08129031 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02417503 0,08117163 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02417503 0,08105331 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02417503 0,08093533 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02417503 0,08081769 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02417503 0,08070039 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02417503 0,08058343 ! spinal cord patterning GO:0021511 7 7 0,000 0,02417503 0,08046682 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02417503 0,08035053 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02417503 0,08023459 ! adrenal gland development GO:0030325 17 7 0,000 0,02417503 0,08011898 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02417503 0,0800037 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02417503 0,07988875 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02417503 0,07977413 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02417503 0,07965984 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02417503 0,07954588 ! endosome organization GO:0007032 10 7 0,000 0,02417503 0,07943224 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02417503 0,07931893 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02417503 0,07920594 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02417503 0,07909327 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02417503 0,07898092 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02417503 0,07886889 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02417503 0,07875718 ! galactose metabolic process GO:0006012 10 7 0,000 0,02417503 0,07864578 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02417503 0,0785347 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02417503 0,07842393 ! organ growth GO:0035265 11 7 0,000 0,02417503 0,07831348 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02417503 0,07820333 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02417503 0,0780935 ! retinol metabolic process GO:0042572 9 7 0,000 0,02417503 0,07798397 ! behavioral fear response GO:0001662 13 7 0,000 0,02417503 0,07787475 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02417503 0,07776583 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02417503 0,07765722 ! rRNA modification GO:0000154 12 7 0,000 0,02417503 0,07754891 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02417503 0,0774409 ! response to UV-B GO:0010224 11 7 0,000 0,02417503 0,0773332 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,02417503 0,07722579 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02417503 0,07711868 ! intermediate filament organization GO:0045109 11 7 0,000 0,02417503 0,07701187 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02417503 0,07690535 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02417503 0,07679913 ! fibrinolysis GO:0042730 9 7 0,000 0,02417503 0,0766932 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02417503 0,07658756 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02417503 0,07648221 ! B cell lineage commitment GO:0002326 17 7 0,000 0,02417503 0,07637716 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02417503 0,07627239 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02417503 0,0761679 ! response to tropane GO:0014073 13 7 0,000 0,02417503 0,07606371 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02417503 0,07595979 ! melanosome localization GO:0032400 10 7 0,000 0,02417503 0,07585617 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02417503 0,07575282 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02417503 0,07564975 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02417503 0,07554697 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02417503 0,07544446 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02417503 0,07534224 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02417503 0,07524028 ! mast cell activation GO:0045576 9 7 0,000 0,02417503 0,07513861 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02417503 0,07503721 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02417503 0,07493608 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02417503 0,07483522 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02417503 0,07473464 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02417503 0,07463432 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02417503 0,07453428 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02417503 0,0744345 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02417503 0,07433499 ! T cell lineage commitment GO:0002360 12 7 0,000 0,02417503 0,07423574 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02417503 0,07413676 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02417503 0,07403804 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02417503 0,07393959 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02417503 0,07384139 ! response to tumor cell GO:0002347 12 7 0,000 0,02417503 0,07374346 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02417503 0,07364579 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02417503 0,07354837 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02417503 0,07345121 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02417503 0,07335431 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02417503 0,07325767 ! diuresis GO:0030146 12 7 0,000 0,02417503 0,07316128 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02417503 0,07306514 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02417503 0,07296925 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02417503 0,07287362 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02417503 0,07277823 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02417503 0,0726831 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02417503 0,07258821 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02417503 0,07249357 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02417503 0,07239918 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02417503 0,07230503 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02417503 0,07221113 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02417503 0,07211747 ! lymph node development GO:0048535 9 7 0,000 0,02417503 0,07202405 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02417503 0,07193088 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02417503 0,07183795 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02417503 0,07174525 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02417503 0,0716528 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02417503 0,07156058 ! ATP catabolic process GO:0006200 10 7 0,000 0,02417503 0,0714686 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02417503 0,07137685 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02417503 0,07128535 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02417503 0,07119407 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02417503 0,07110303 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02417503 0,07101222 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02417503 0,07092164 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02417503 0,0708313 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02417503 0,07074118 ! retina homeostasis GO:0001895 9 7 0,000 0,02417503 0,0706513 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02417503 0,07056164 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02417503 0,0704722 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02417503 0,070383 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02417503 0,07029402 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02417503 0,07020526 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02417503 0,07011673 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02417503 0,07002843 ! humoral immune response GO:0006959 86 70 1,000 0,02484594 0,07188134 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,02550954 0,07370848 ! muscle cell differentiation GO:0042692 104 71 1,000 0,02550954 0,073616 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,02550954 0,07352375 ! tube morphogenesis GO:0035239 118 73 1,000 0,02685829 0,07731422 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02758134 0,07929636 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02758134 0,07919737 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02758134 0,07909862 ! axon extension GO:0048675 11 8 0,000 0,02758134 0,07900011 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02758134 0,07890185 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02758134 0,07880384 ! associative learning GO:0008306 15 8 0,000 0,02758134 0,07870607 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02758134 0,07860854 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02758134 0,07851125 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02758134 0,0784142 ! phosphate transport GO:0006817 10 8 0,000 0,02758134 0,07831739 ! N-glycan processing GO:0006491 12 8 0,000 0,02758134 0,07822083 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02758134 0,07812449 ! UTP metabolic process GO:0046051 8 8 0,000 0,02758134 0,0780284 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02758134 0,07793254 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02758134 0,07783692 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02758134 0,07774153 ! succinate metabolic process GO:0006105 14 8 0,000 0,02758134 0,07764638 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02758134 0,07755145 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02758134 0,07745676 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02758134 0,0773623 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02758134 0,07726808 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02758134 0,07717408 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02758134 0,0770803 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02758134 0,07698676 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02758134 0,07689344 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02758134 0,07680035 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02758134 0,07670748 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02758134 0,07661484 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02758134 0,07652242 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02758134 0,07643023 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02758134 0,07633825 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02758134 0,0762465 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02758134 0,07615497 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02758134 0,07606366 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02758134 0,07597256 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02758134 0,07588169 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02758134 0,07579103 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02758134 0,07570058 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02758134 0,07561036 ! melanin metabolic process GO:0006582 12 8 0,000 0,02758134 0,07552035 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02758134 0,07543055 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02758134 0,07534096 ! macrophage activation GO:0042116 12 8 0,000 0,02758134 0,07525159 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02758134 0,07516243 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02758134 0,07507348 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02758134 0,07498474 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02758134 0,07489621 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02758134 0,07480789 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02758134 0,07471978 ! ruffle organization GO:0031529 11 8 0,000 0,02758134 0,07463187 ! osteoblast development GO:0002076 13 8 0,000 0,02758134 0,07454417 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02758134 0,07445668 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02758134 0,07436939 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02758134 0,07428231 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02758134 0,07419543 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02758134 0,07410875 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02758134 0,07402228 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02758134 0,073936 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02758134 0,07384993 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02758134 0,07376406 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02758134 0,07367839 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02758134 0,07359291 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02758134 0,07350764 ! segment specification GO:0007379 10 8 0,000 0,02758134 0,07342256 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02758134 0,07333768 ! cellular extravasation GO:0045123 11 8 0,000 0,02758134 0,07325299 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02758134 0,0731685 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02758134 0,0730842 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02758134 0,0730001 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02758134 0,0729162 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02758134 0,07283248 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02758134 0,07274896 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02758134 0,07266562 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02758134 0,07258248 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02758134 0,07249953 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02758134 0,07241677 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02758134 0,0723342 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02758134 0,07225181 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02758134 0,07216961 ! icosanoid secretion GO:0032309 12 8 0,000 0,02758134 0,0720876 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02758134 0,07200578 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02758134 0,07192414 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02758134 0,07184268 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02758134 0,07176141 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02758134 0,07168033 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02758134 0,07159942 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02758134 0,0715187 ! sterol catabolic process GO:0016127 9 8 0,000 0,02758134 0,07143816 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02758134 0,07135781 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02758134 0,07127763 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02758134 0,07119763 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02758134 0,07111781 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02758134 0,07103817 ! prophase GO:0051324 11 8 0,000 0,02758134 0,07095871 ! S phase GO:0051320 8 8 0,000 0,02758134 0,07087943 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02758134 0,07080032 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02758134 0,07072139 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02758134 0,07064264 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02758134 0,07056406 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02758134 0,07048566 ! hormone catabolic process GO:0042447 13 8 0,000 0,02758134 0,07040742 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02758134 0,07032937 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02758134 0,07025148 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02758134 0,07017377 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02758134 0,07009623 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02758134 0,07001886 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02758134 0,06994166 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02758134 0,06986464 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02758134 0,06978778 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02758134 0,06971109 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02758134 0,06963457 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02758134 0,06955821 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02758134 0,06948203 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02758134 0,06940601 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02758134 0,06933015 ! blood coagulation GO:0007596 116 75 1,000 0,02823538 0,0708967 GO:0050817|coagulation, ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,02893442 0,07257269 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,03035319 0,0760483 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03097596 0,07752417 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03097596 0,0774399 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03097596 0,07735582 ! CTP metabolic process GO:0046036 9 9 0,000 0,03097596 0,07727192 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03097596 0,0771882 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03097596 0,07710466 ! GTP metabolic process GO:0046039 9 9 0,000 0,03097596 0,07702131 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03097596 0,07693813 ! social behavior GO:0035176 14 9 0,000 0,03097596 0,07685513 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03097596 0,07677232 ! artery development GO:0060840 19 9 0,000 0,03097596 0,07668968 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03097596 0,07660721 ! response to pain GO:0048265 16 9 0,000 0,03097596 0,07652493 ! protein complex disassembly GO:0043241 17 9 0,000 0,03097596 0,07644282 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03097596 0,07636089 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03097596 0,07627913 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03097596 0,07619755 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03097596 0,07611614 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03097596 0,07603491 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03097596 0,07595385 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03097596 0,07587296 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03097596 0,07579224 ! protein targeting to ER GO:0045047 19 9 0,000 0,03097596 0,0757117 ! T cell selection GO:0045058 18 9 0,000 0,03097596 0,07563133 ! endoderm development GO:0007492 12 9 0,000 0,03097596 0,07555112 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03097596 0,07547109 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03097596 0,07539123 ! arginine catabolic process GO:0006527 10 9 0,000 0,03097596 0,07531153 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03097596 0,07523201 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03097596 0,07515265 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03097596 0,07507346 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03097596 0,07499443 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03097596 0,07491557 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03097596 0,07483688 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03097596 0,07475835 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03097596 0,07467999 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03097596 0,07460179 ! mannose metabolic process GO:0006013 9 9 0,000 0,03097596 0,07452375 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03097596 0,07444588 ! receptor clustering GO:0043113 15 9 0,000 0,03097596 0,07436817 ! epithelial cell development GO:0002064 10 9 0,000 0,03097596 0,07429062 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03097596 0,07421324 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03097596 0,07413601 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03097596 0,07405895 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03097596 0,07398204 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03097596 0,0739053 ! motor axon guidance GO:0008045 14 9 0,000 0,03097596 0,07382871 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03097596 0,07375229 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03097596 0,07367602 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03097596 0,07359991 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03097596 0,07352395 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03097596 0,07344815 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03097596 0,07337251 ! DNA ligation GO:0006266 14 9 0,000 0,03097596 0,07329703 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03097596 0,07322169 ! response to amine stimulus GO:0014075 13 9 0,000 0,03097596 0,07314652 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03097596 0,0730715 ! erythrocyte development GO:0048821 11 9 0,000 0,03097596 0,07299663 ! renal water homeostasis GO:0003091 14 9 0,000 0,03097596 0,07292191 ! postreplication repair GO:0006301 11 9 0,000 0,03097596 0,07284735 ! mRNA cleavage GO:0006379 13 9 0,000 0,03097596 0,07277294 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03097596 0,07269868 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03097596 0,07262458 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03097596 0,07255062 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03097596 0,07247681 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03097596 0,07240316 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03097596 0,07232965 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03097596 0,0722563 ! acid secretion GO:0046717 14 9 0,000 0,03097596 0,07218309 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03097596 0,07211003 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03097596 0,07203712 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03097596 0,07196435 ! purine base metabolic process GO:0006144 18 9 0,000 0,03097596 0,07189173 ! oocyte differentiation GO:0009994 12 9 0,000 0,03097596 0,07181926 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03097596 0,07174694 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03097596 0,07167476 ! spleen development GO:0048536 15 9 0,000 0,03097596 0,07160272 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03097596 0,07153083 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03097596 0,07145909 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03097596 0,07138748 ! detection of calcium ion GO:0005513 13 9 0,000 0,03097596 0,07131603 ! blastocyst formation GO:0001825 12 9 0,000 0,03097596 0,07124471 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03097596 0,07117354 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03097596 0,0711025 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03097596 0,07103161 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03097596 0,07096087 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03097596 0,07089026 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03097596 0,07081979 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03097596 0,07074946 ! prepulse inhibition GO:0060134 14 9 0,000 0,03097596 0,07067927 ! embryonic placenta development GO:0001892 12 9 0,000 0,03097596 0,07060923 ! insulin secretion GO:0030073 17 9 0,000 0,03097596 0,07053932 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03097596 0,07046954 ! response to nicotine GO:0035094 16 9 0,000 0,03097596 0,07039991 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03097596 0,07033041 ! nucleus localization GO:0051647 15 9 0,000 0,03097596 0,07026105 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03097596 0,07019183 ! cellular respiration GO:0045333 107 79 1,000 0,03107282 0,07034201 ! oxidative phosphorylation GO:0006119 105 79 1,000 0,03107282 0,07027285 ! hemostasis GO:0007599 125 81 1,000 0,03253229 0,07350124 ! mRNA transport GO:0051028 121 81 1,000 0,03253229 0,07342911 ! ossification GO:0001503 134 82 1,000 0,03327202 0,07502514 GO:0060348|bone development, ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03435892 0,07740012 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03435892 0,07732438 ! neuron fate specification GO:0048665 11 10 0,000 0,03435892 0,0772488 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03435892 0,07717336 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03435892 0,07709807 ! thyroid gland development GO:0030878 19 10 0,000 0,03435892 0,07702292 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03435892 0,07694792 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03435892 0,07687307 ! synapsis GO:0007129 13 10 0,000 0,03435892 0,07679837 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03435892 0,0767238 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03435892 0,07664939 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03435892 0,07657511 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03435892 0,07650099 ! sulfate transport GO:0008272 12 10 0,000 0,03435892 0,076427 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03435892 0,07635316 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03435892 0,07627946 ! androgen metabolic process GO:0008209 13 10 0,000 0,03435892 0,0762059 ! phospholipid efflux GO:0033700 16 10 0,000 0,03435892 0,07613248 ! hippocampus development GO:0021766 19 10 0,000 0,03435892 0,07605921 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,03435892 0,07598607 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03435892 0,07591308 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03435892 0,07584023 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03435892 0,07576751 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03435892 0,07569494 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03435892 0,07562251 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03435892 0,07555021 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03435892 0,07547805 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,03435892 0,07540603 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03435892 0,07533414 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03435892 0,0752624 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03435892 0,07519079 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03435892 0,07511931 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03435892 0,07504798 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03435892 0,07497677 ! response to X-ray GO:0010165 16 10 0,000 0,03435892 0,0749057 ! B cell proliferation GO:0042100 14 10 0,000 0,03435892 0,07483477 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03435892 0,07476397 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03435892 0,07469331 ! forebrain cell migration GO:0021885 17 10 0,000 0,03435892 0,07462277 ! lipid digestion GO:0044241 15 10 0,000 0,03435892 0,07455238 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03435892 0,07448211 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03435892 0,07441198 ! UV protection GO:0009650 14 10 0,000 0,03435892 0,07434197 ! entry into host cell GO:0030260 20 10 0,000 0,03435892 0,0742721 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03435892 0,07420236 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03435892 0,07413276 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03435892 0,07406328 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03435892 0,07399393 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03435892 0,07392471 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03435892 0,07385562 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03435892 0,07378666 ! regulation of organ growth GO:0046620 11 10 0,000 0,03435892 0,07371783 ! response to dsRNA GO:0043331 18 10 0,000 0,03435892 0,07364913 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03435892 0,07358056 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03435892 0,07351211 ! embryonic axis specification GO:0000578 12 10 0,000 0,03435892 0,07344379 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03435892 0,0733756 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03435892 0,07330753 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03435892 0,07323959 ! cranial nerve development GO:0021545 12 10 0,000 0,03435892 0,07317178 ! fucose catabolic process GO:0019317 16 10 0,000 0,03435892 0,07310409 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03435892 0,07303652 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03435892 0,07296908 ! protein sumoylation GO:0016925 12 10 0,000 0,03435892 0,07290177 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03435892 0,07283458 ! zymogen activation GO:0031638 14 10 0,000 0,03435892 0,07276751 ! salivary gland development GO:0007431 22 10 0,000 0,03435892 0,07270057 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03435892 0,07263375 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03435892 0,07256705 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03435892 0,07250048 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03435892 0,07243402 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03435892 0,07236769 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03435892 0,07230148 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03435892 0,07223539 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03435892 0,07216942 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03435892 0,07210357 ! detection of bacterium GO:0016045 10 10 0,000 0,03435892 0,07203785 ! embryonic gut development GO:0048566 11 10 0,000 0,03435892 0,07197224 ! activation of innate immune response GO:0002218 10 10 0,000 0,03435892 0,07190675 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03435892 0,07184138 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03435892 0,07177613 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03435892 0,071711 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03435892 0,07164598 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03435892 0,07158109 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03435892 0,07151631 ! regulation of membrane potential GO:0042391 128 85 1,000 0,03553056 0,07388815 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 0,03629635 0,07541246 ! rRNA transcription GO:0009303 17 11 0,000 0,03773026 0,07832094 ! respiratory burst GO:0045730 14 11 0,000 0,03773026 0,07825032 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03773026 0,07817983 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03773026 0,07810946 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03773026 0,07803921 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03773026 0,0779691 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03773026 0,07789911 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03773026 0,07782924 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03773026 0,0777595 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03773026 0,07768989 ! mating GO:0007618 14 11 0,000 0,03773026 0,0776204 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03773026 0,07755103 ! T cell proliferation GO:0042098 20 11 0,000 0,03773026 0,07748179 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03773026 0,07741267 ! bone resorption GO:0045453 16 11 0,000 0,03773026 0,07734368 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03773026 0,07727481 ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03773026 0,07720606 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03773026 0,07713743 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03773026 0,07706892 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03773026 0,07700054 ! syncytium formation GO:0006949 15 11 0,000 0,03773026 0,07693228 ! plasma membrane organization GO:0007009 18 11 0,000 0,03773026 0,07686413 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03773026 0,07679611 ! focal adhesion formation GO:0048041 24 11 0,000 0,03773026 0,07672821 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03773026 0,07666043 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03773026 0,07659277 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03773026 0,07652523 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03773026 0,0764578 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03773026 0,0763905 ! adult heart development GO:0007512 11 11 0,000 0,03773026 0,07632331 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03773026 0,07625625 ! temperature homeostasis GO:0001659 16 11 0,000 0,03773026 0,07618929 ! L-glutamate transport GO:0015813 16 11 0,000 0,03773026 0,07612246 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03773026 0,07605575 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03773026 0,07598915 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03773026 0,07592267 ! protein homotetramerization GO:0051289 18 11 0,000 0,03773026 0,0758563 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03773026 0,07579005 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03773026 0,07572392 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03773026 0,0756579 ! vasoconstriction GO:0042310 15 11 0,000 0,03773026 0,07559199 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03773026 0,0755262 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03773026 0,07546053 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03773026 0,07539497 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03773026 0,07532952 ! ribosome assembly GO:0042255 13 11 0,000 0,03773026 0,07526419 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03773026 0,07519897 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03773026 0,07513386 ! chromatin silencing GO:0006342 19 11 0,000 0,03773026 0,07506886 ! nucleosome positioning GO:0016584 13 11 0,000 0,03773026 0,07500398 ! T cell homeostasis GO:0043029 20 11 0,000 0,03773026 0,07493921 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03773026 0,07487455 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03773026 0,07481001 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03773026 0,07474557 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03773026 0,07468125 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03773026 0,07461703 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03773026 0,07455293 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03773026 0,07448893 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03773026 0,07442505 ! male genitalia development GO:0030539 13 11 0,000 0,03773026 0,07436127 ! cholesterol efflux GO:0033344 19 11 0,000 0,03773026 0,07429761 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03773026 0,07423405 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03773026 0,0741706 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03773026 0,07410726 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03773026 0,07404403 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03773026 0,07398091 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03773026 0,07391789 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,03773026 0,07385498 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,03773026 0,07379218 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03773026 0,07372949 ! lysogeny GO:0030069 18 11 0,000 0,03773026 0,0736669 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03773026 0,07360442 ! acrosome reaction GO:0007340 13 11 0,000 0,03773026 0,07354204 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03773026 0,07347977 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,03784701 0,07364477 ! interphase GO:0051325 159 88 1,000 0,03784701 0,07358252 ! establishment of RNA localization GO:0051236 128 88 1,000 0,03784701 0,07352037 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,03784701 0,07345833 ! reproductive developmental process GO:0003006 127 89 1,000 0,03863178 0,0749183 ! RNA localization GO:0006403 135 91 1,000 0,04021996 0,07793252 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,04102325 0,07942212 ! positive regulation of immune response GO:0050778 121 92 1,000 0,04102325 0,07935532 ! cell fate commitment GO:0045165 141 92 1,000 0,04102325 0,07928864 ! sulfur metabolic process GO:0006790 118 92 1,000 0,04102325 0,07922206 ! lactation GO:0007595 20 12 0,000 0,04109003 0,07928445 ! reproductive cellular process GO:0048610 14 12 0,000 0,04109003 0,07921799 ! tRNA modification GO:0006400 14 12 0,000 0,04109003 0,07915165 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04109003 0,07908541 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04109003 0,07901929 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04109003 0,07895327 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04109003 0,07888737 ! non-recombinational repair GO:0000726 19 12 0,000 0,04109003 0,07882157 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04109003 0,07875589 ! peroxisomal transport GO:0043574 21 12 0,000 0,04109003 0,07869031 ! cartilage condensation GO:0001502 18 12 0,000 0,04109003 0,07862485 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04109003 0,07855949 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04109003 0,07849424 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04109003 0,0784291 ! heart looping GO:0001947 15 12 0,000 0,04109003 0,07836407 ! palate development GO:0060021 15 12 0,000 0,04109003 0,07829914 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04109003 0,07823433 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04109003 0,07816962 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04109003 0,07810501 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04109003 0,07804052 ! arginine metabolic process GO:0006525 13 12 0,000 0,04109003 0,07797613 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04109003 0,07791184 ! methionine metabolic process GO:0006555 13 12 0,000 0,04109003 0,07784767 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04109003 0,07778359 ! Golgi organization GO:0007030 18 12 0,000 0,04109003 0,07771963 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04109003 0,07765577 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04109003 0,07759201 ! monoamine transport GO:0015844 13 12 0,000 0,04109003 0,07752836 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04109003 0,07746481 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04109003 0,07740136 ! L-amino acid transport GO:0015807 20 12 0,000 0,04109003 0,07733802 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04109003 0,07727479 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04109003 0,07721166 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04109003 0,07714863 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04109003 0,0770857 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04109003 0,07702287 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04109003 0,07696015 ! cerebellum development GO:0021549 13 12 0,000 0,04109003 0,07689753 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04109003 0,07683501 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04109003 0,0767726 ! histone acetylation GO:0016573 23 12 0,000 0,04109003 0,07671028 ! histone methylation GO:0016571 15 12 0,000 0,04109003 0,07664807 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04109003 0,07658595 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04109003 0,07652394 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,04109003 0,07646203 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04109003 0,07640022 ! response to gamma radiation GO:0010332 20 12 0,000 0,04109003 0,0763385 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04109003 0,07627689 ! intestinal absorption GO:0050892 19 12 0,000 0,04109003 0,07621538 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04109003 0,07615396 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04109003 0,07609265 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04109003 0,07603143 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04109003 0,07597031 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04109003 0,07590929 ! microspike assembly GO:0030035 23 12 0,000 0,04109003 0,07584837 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04109003 0,07578754 ! response to cold GO:0009409 14 12 0,000 0,04109003 0,07572682 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,04183262 0,07703365 ! electron transport chain GO:0022900 123 94 1,000 0,04264801 0,07847234 ! in utero embryonic development GO:0001701 147 96 1,000 0,04429665 0,08144069 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,04429665 0,08137564 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,04429665 0,08131069 ! protein maturation GO:0051604 129 96 1,000 0,04429665 0,08124585 ! response to light stimulus GO:0009416 153 96 1,000 0,04429665 0,08118111 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,04443825 0,08137579 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04443825 0,08131105 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04443825 0,08124641 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04443825 0,08118188 ! water transport GO:0006833 17 13 0,000 0,04443825 0,08111745 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04443825 0,08105312 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04443825 0,0809889 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04443825 0,08092477 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04443825 0,08086075 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04443825 0,08079683 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04443825 0,08073301 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04443825 0,08066929 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04443825 0,08060567 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04443825 0,08054215 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04443825 0,08047873 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04443825 0,08041541 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04443825 0,08035219 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04443825 0,08028907 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04443825 0,08022605 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04443825 0,08016313 ! NAD metabolic process GO:0019674 21 13 0,000 0,04443825 0,0801003 ! exocrine system development GO:0035272 27 13 0,000 0,04443825 0,08003758 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04443825 0,07997495 ! bone mineralization GO:0030282 15 13 0,000 0,04443825 0,07991242 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04443825 0,07984999 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04443825 0,07978766 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04443825 0,07972542 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04443825 0,07966328 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04443825 0,07960124 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04443825 0,07953929 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,04443825 0,07947744 ! genitalia development GO:0048806 15 13 0,000 0,04443825 0,07941568 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04443825 0,07935403 ! cellular pigmentation GO:0033059 24 13 0,000 0,04443825 0,07929246 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04443825 0,079231 ! cofactor transport GO:0051181 19 13 0,000 0,04443825 0,07916963 ! NADP metabolic process GO:0006739 18 13 0,000 0,04443825 0,07910835 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04443825 0,07904717 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04443825 0,07898608 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04443825 0,07892509 ! gas transport GO:0015669 18 13 0,000 0,04443825 0,07886419 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04443825 0,07880338 ! regulation of axon extension GO:0030516 23 13 0,000 0,04443825 0,07874267 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04443825 0,07868205 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04443825 0,07862153 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04443825 0,0785611 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04443825 0,07850076 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04443825 0,07844051 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04443825 0,07838036 ! calcium ion transport GO:0006816 167 99 1,000 0,04681353 0,0825066 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,047664 0,08394119 ! divalent metal ion transport GO:0070838 171 100 1,000 0,047664 0,08387697 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,047664 0,08381284 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,047664 0,08374881 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04777498 0,08387974 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,04777498 0,08381576 ! superoxide anion generation GO:0042554 18 14 0,000 0,04777498 0,08375187 ! neuron maturation GO:0042551 21 14 0,000 0,04777498 0,08368809 ! regulation of S phase GO:0033261 18 14 0,000 0,04777498 0,0836244 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04777498 0,0835608 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04777498 0,08349731 ! inositol metabolic process GO:0006020 20 14 0,000 0,04777498 0,08343391 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04777498 0,0833706 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04777498 0,0833074 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04777498 0,08324428 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04777498 0,08318127 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04777498 0,08311835 ! response to cAMP GO:0051591 19 14 0,000 0,04777498 0,08305552 ! limbic system development GO:0021761 25 14 0,000 0,04777498 0,08299279 ! startle response GO:0001964 21 14 0,000 0,04777498 0,08293016 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04777498 0,08286761 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04777498 0,08280517 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04777498 0,08274281 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04777498 0,08268055 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04777498 0,08261839 ! glycine metabolic process GO:0006544 22 14 0,000 0,04777498 0,08255632 ! pituitary gland development GO:0021983 23 14 0,000 0,04777498 0,08249434 ! cellular response to starvation GO:0009267 21 14 0,000 0,04777498 0,08243245 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04777498 0,08237066 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04777498 0,08230896 ! regulation of heart rate GO:0002027 23 14 0,000 0,04777498 0,08224735 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04777498 0,08218583 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04777498 0,08212441 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04777498 0,08206307 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04777498 0,08200183 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,04777498 0,08194068 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,04777498 0,08187962 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04777498 0,08181866 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04777498 0,08175778 ! axon cargo transport GO:0008088 27 14 0,000 0,04777498 0,08169699 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04777498 0,0816363 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04777498 0,08157569 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04777498 0,08151518 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04777498 0,08145475 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04777498 0,08139441 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04777498 0,08133416 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04777498 0,08127401 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04777498 0,08121394 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04777498 0,08115396 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04777498 0,08109406 GO:0046466|membrane lipid catabolic process, ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04777498 0,08103426 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04777498 0,08097454 ! muscle maintenance GO:0046716 19 14 0,000 0,04777498 0,08091492 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04777498 0,08085538 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04777498 0,08079592 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04777498 0,08073656 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04777498 0,08067728 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,04777498 0,08061809 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,04777498 0,08055899 ! cilium assembly GO:0042384 20 14 0,000 0,04777498 0,08049997 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04777498 0,08044104 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05110025 0,085977 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05110025 0,08591416 ! metencephalon development GO:0022037 19 15 0,000 0,05110025 0,0858514 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05110025 0,08578873 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05110025 0,08572616 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05110025 0,08566368 ! skin development GO:0043588 25 15 0,000 0,05110025 0,08560129 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05110025 0,08553898 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05110025 0,08547677 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05110025 0,08541465 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05110025 0,08535263 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05110025 0,08529069 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05110025 0,08522884 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05110025 0,08516708 ! adult walking behavior GO:0007628 25 15 0,000 0,05110025 0,08510541 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05110025 0,08504382 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05110025 0,08498233 ! centrosome cycle GO:0007098 16 15 0,000 0,05110025 0,08492093 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05110025 0,08485961 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05110025 0,08479839 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05110025 0,08473725 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05110025 0,0846762 ! cerebral cortex development GO:0021987 29 15 0,000 0,05110025 0,08461524 ! response to osmotic stress GO:0006970 22 15 0,000 0,05110025 0,08455436 ! vesicle coating GO:0006901 25 15 0,000 0,05110025 0,08449358 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05110025 0,08443288 ! DNA integration GO:0015074 22 15 0,000 0,05110025 0,08437226 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05110025 0,08431174 ! peptide secretion GO:0002790 27 15 0,000 0,05110025 0,0842513 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05110025 0,08419095 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05110025 0,08413068 ! neuron recognition GO:0008038 22 15 0,000 0,05110025 0,0840705 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05110025 0,08401041 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05110025 0,0839504 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05110025 0,08389048 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05110025 0,08383065 ! biomineral formation GO:0031214 18 15 0,000 0,05110025 0,08377089 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05110025 0,08371123 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05110025 0,08365165 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05110025 0,08359215 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05110025 0,08353274 ! organic cation transport GO:0015695 19 15 0,000 0,05110025 0,08347341 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05110025 0,08341417 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05110025 0,08335501 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,05110025 0,08329594 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,05110025 0,08323694 ! defense response to virus GO:0051607 27 15 0,000 0,05110025 0,08317804 ! peptide hormone processing GO:0016486 19 15 0,000 0,05110025 0,08311921 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05110025 0,08306047 ! protein secretion GO:0009306 27 16 0,000 0,05441409 0,08838447 ! hormone secretion GO:0046879 25 16 0,000 0,05441409 0,08832209 ! bone remodeling GO:0046849 24 16 0,000 0,05441409 0,0882598 ! endothelial cell migration GO:0043542 22 16 0,000 0,05441409 0,08819761 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05441409 0,08813549 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,05441409 0,08807347 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05441409 0,08801153 ! glial cell development GO:0021782 24 16 0,000 0,05441409 0,08794969 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05441409 0,08788792 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05441409 0,08782625 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05441409 0,08776466 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05441409 0,08770316 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,05441409 0,08764174 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05441409 0,08758041 ! fructose metabolic process GO:0006000 20 16 0,000 0,05441409 0,08751916 ! regulation of protein binding GO:0043393 27 16 0,000 0,05441409 0,087458 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05441409 0,08739693 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05441409 0,08733594 ! protein export from nucleus GO:0006611 24 16 0,000 0,05441409 0,08727504 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05441409 0,08721422 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05441409 0,08715348 ! DNA replication initiation GO:0006270 25 16 0,000 0,05441409 0,08709283 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05441409 0,08703227 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05441409 0,08697179 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05441409 0,08691139 ! diencephalon development GO:0021536 25 16 0,000 0,05441409 0,08685108 ! oogenesis GO:0048477 23 16 0,000 0,05441409 0,08679085 ! neural crest cell migration GO:0001755 24 16 0,000 0,05441409 0,0867307 ! G1 phase GO:0051318 27 16 0,000 0,05441409 0,08667064 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,05441409 0,08661066 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05441409 0,08655076 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05441409 0,08649095 ! steroid catabolic process GO:0006706 22 16 0,000 0,05441409 0,08643122 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05441409 0,08637157 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05441409 0,086312 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05441409 0,08625252 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05441409 0,08619311 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05441409 0,08613379 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,05441409 0,08607455 ! nerve development GO:0021675 18 16 0,000 0,05441409 0,0860154 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05441409 0,08595632 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05441409 0,08589733 ! negative regulation of translation GO:0017148 22 16 0,000 0,05441409 0,08583841 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,05771655 0,09098565 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,05771655 0,09092333 ! negative regulation of defense response GO:0031348 19 17 0,000 0,05771655 0,09086109 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,05771655 0,09079894 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,05771655 0,09073688 ! glycerol metabolic process GO:0006071 20 17 0,000 0,05771655 0,0906749 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,05771655 0,09061301 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,05771655 0,0905512 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,05771655 0,09048947 ! signal complex assembly GO:0007172 29 17 0,000 0,05771655 0,09042783 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,05771655 0,09036627 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,05771655 0,0903048 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,05771655 0,09024341 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,05771655 0,0901821 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,05771655 0,09012088 ! memory GO:0007613 25 17 0,000 0,05771655 0,09005974 ! keratinization GO:0031424 17 17 0,000 0,05771655 0,08999868 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,05771655 0,08993771 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,05771655 0,08987682 ! retinoid metabolic process GO:0001523 22 17 0,000 0,05771655 0,08981601 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,05771655 0,08975528 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,05771655 0,08969463 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,05771655 0,08963407 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,05771655 0,08957359 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,05771655 0,08951319 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,05771655 0,08945287 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,05771655 0,08939263 ! membrane budding GO:0006900 29 17 0,000 0,05771655 0,08933247 ! heme metabolic process GO:0042168 27 17 0,000 0,05771655 0,0892724 ! actin filament bundle formation GO:0051017 26 17 0,000 0,05771655 0,0892124 ! neuromuscular junction development GO:0007528 23 17 0,000 0,05771655 0,08915249 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,05771655 0,08909266 ! body fluid secretion GO:0007589 27 17 0,000 0,05771655 0,0890329 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,05771655 0,08897323 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,05771655 0,08891364 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,05771655 0,08885412 ! sensory perception of pain GO:0019233 23 17 0,000 0,05771655 0,08879469 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,05771655 0,08873533 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,05771655 0,08867606 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,05771655 0,08861686 ! synaptogenesis GO:0007416 24 17 0,000 0,05771655 0,08855774 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,05771655 0,0884987 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,05771655 0,08843974 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,05771655 0,08838086 ! cell-cell junction organization GO:0045216 25 17 0,000 0,05771655 0,08832206 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,05771655 0,08826334 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,05771655 0,08820469 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,05771655 0,08814612 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,05771655 0,08808763 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,05771655 0,08802922 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,06100766 0,09298716 ! positive regulation of translation GO:0045727 28 18 0,000 0,06100766 0,09292557 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06100766 0,09286408 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,06100766 0,09280266 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06100766 0,09274132 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06100766 0,09268006 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06100766 0,09261889 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06100766 0,0925578 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06100766 0,09249678 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06100766 0,09243585 ! axis specification GO:0009798 26 18 0,000 0,06100766 0,09237499 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06100766 0,09231422 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06100766 0,09225353 ! pancreas development GO:0031016 26 18 0,000 0,06100766 0,09219292 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,06100766 0,09213238 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06100766 0,09207193 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06100766 0,09201155 ! response to retinoic acid GO:0032526 25 18 0,000 0,06100766 0,09195126 ! pigmentation during development GO:0048066 31 18 0,000 0,06100766 0,09189104 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06100766 0,0918309 ! fucose metabolic process GO:0006004 26 18 0,000 0,06100766 0,09177084 ! response to fungus GO:0009620 19 18 0,000 0,06100766 0,09171086 ! peptide cross-linking GO:0018149 31 18 0,000 0,06100766 0,09165096 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06100766 0,09159113 ! heart process GO:0003015 27 18 0,000 0,06100766 0,09153139 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06100766 0,09147172 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06100766 0,09141213 ! visual learning GO:0008542 35 18 0,000 0,06100766 0,09135262 ! somitogenesis GO:0001756 24 18 0,000 0,06100766 0,09129318 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06100766 0,09123382 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06100766 0,09117454 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06100766 0,09111534 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,06100766 0,09105621 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06100766 0,09099716 ! vitamin transport GO:0051180 24 18 0,000 0,06100766 0,09093818 ! hormone transport GO:0009914 27 18 0,000 0,06100766 0,09087929 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,06100766 0,09082046 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,06100766 0,09076172 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06100766 0,09070305 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06100766 0,09064446 ! cell-cell recognition GO:0009988 20 18 0,000 0,06100766 0,09058594 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06100766 0,0905275 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06100766 0,09046913 ! regulation of glucose import GO:0046324 21 18 0,000 0,06100766 0,09041084 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,06100766 0,09035262 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06100766 0,09029448 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,06100766 0,09023641 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,06100766 0,09017842 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06428747 0,09496543 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,06428747 0,09490447 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06428747 0,0948436 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06428747 0,0947828 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,06428747 0,09472208 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06428747 0,09466144 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06428747 0,09460088 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06428747 0,09454039 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,06428747 0,09447998 ! response to alkaloid GO:0043279 32 19 0,000 0,06428747 0,09441965 ! sensory perception of taste GO:0050909 23 19 0,000 0,06428747 0,09435939 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,06428747 0,09429922 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06428747 0,09423911 ! peroxisome organization GO:0007031 29 19 0,000 0,06428747 0,09417909 ! digestive system process GO:0022600 30 19 0,000 0,06428747 0,09411914 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06428747 0,09405927 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06428747 0,09399947 ! response to vitamin A GO:0033189 26 19 0,000 0,06428747 0,09393975 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06428747 0,09388011 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06428747 0,09382054 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,06428747 0,09376105 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,06428747 0,09370163 ! response to starvation GO:0042594 30 19 0,000 0,06428747 0,09364229 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,06428747 0,09358302 ! plasma membrane fusion GO:0045026 23 19 0,000 0,06428747 0,09352383 ! renal system process GO:0003014 35 19 0,000 0,06428747 0,09346471 ! vasodilation GO:0042311 33 19 0,000 0,06428747 0,09340567 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06428747 0,0933467 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06428747 0,09328781 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,06428747 0,09322899 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,06428747 0,09317024 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,06428747 0,09311157 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06428747 0,09305297 ! sarcomere organization GO:0045214 23 19 0,000 0,06428747 0,09299445 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,06428747 0,092936 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06428747 0,09287762 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06428747 0,09281932 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06428747 0,09276109 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,06428747 0,09270293 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,06428747 0,09264484 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,06428747 0,09258683 ! protein stabilization GO:0050821 26 19 0,000 0,06428747 0,09252889 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,067556 0,09717249 ! iron ion transport GO:0006826 37 20 0,000 0,067556 0,09711175 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,067556 0,0970511 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,067556 0,09699052 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,067556 0,09693001 ! response to vitamin GO:0033273 29 20 0,000 0,067556 0,09686958 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,067556 0,09680923 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,067556 0,09674895 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,067556 0,09668874 ! spinal cord development GO:0021510 31 20 0,000 0,067556 0,09662861 ! response to ethanol GO:0045471 37 20 0,000 0,067556 0,09656856 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,067556 0,09650858 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,067556 0,09644867 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,067556 0,09638884 ! chromosome condensation GO:0030261 31 20 0,000 0,067556 0,09632908 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,067556 0,0962694 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,067556 0,09620979 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,067556 0,09615025 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,067556 0,09609079 ! pallium development GO:0021543 38 20 0,000 0,067556 0,0960314 ! DNA modification GO:0006304 28 20 0,000 0,067556 0,09597209 ! collagen fibril organization GO:0030199 45 20 0,000 0,067556 0,09591284 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,067556 0,09585367 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,067556 0,09579458 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,067556 0,09573556 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,067556 0,09567661 ! collagen catabolic process GO:0030574 25 20 0,000 0,067556 0,09561773 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,067556 0,09555892 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,067556 0,09550019 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,067556 0,09544153 ! alditol metabolic process GO:0019400 24 20 0,000 0,067556 0,09538294 ! actin filament-based movement GO:0030048 34 20 0,000 0,067556 0,09532442 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07081331 0,09985936 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07081331 0,09979817 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07081331 0,09973706 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,07081331 0,09967602 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07081331 0,09961505 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07081331 0,09955416 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07081331 0,09949335 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07081331 0,09943261 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07081331 0,09937194 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07081331 0,09931135 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07081331 0,09925083 ! protein amino acid acylation GO:0043543 37 21 0,000 0,07081331 0,09919038 ! phototransduction GO:0007602 25 21 0,000 0,07081331 0,09913001 ! dendrite development GO:0016358 35 21 0,000 0,07081331 0,09906971 ! visual behavior GO:0007632 39 21 0,000 0,07081331 0,09900949 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07081331 0,09894934 ! ovarian follicle development GO:0001541 30 21 0,000 0,07081331 0,09888926 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,07081331 0,09882925 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07081331 0,09876932 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07081331 0,09870946 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07081331 0,09864967 ! cell aging GO:0007569 32 21 0,000 0,07081331 0,09858996 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,07081331 0,09853032 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,07081331 0,09847074 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07081331 0,09841125 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07081331 0,09835182 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07081331 0,09829246 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07081331 0,09823318 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07081331 0,09817397 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07081331 0,09811483 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07081331 0,09805576 ! fatty acid transport GO:0015908 30 21 0,000 0,07081331 0,09799676 ! immunoglobulin production GO:0002377 33 21 0,000 0,07081331 0,09793783 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07081331 0,09787897 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,07081331 0,09782019 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07081331 0,09776147 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07081331 0,09770283 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,07081331 0,09764425 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07081331 0,09758575 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07081331 0,09752731 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07081331 0,09746895 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07081331 0,09741065 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07081331 0,09735243 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07081331 0,09729427 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07081331 0,09723619 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07081331 0,09717817 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07081331 0,09712022 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07081331 0,09706234 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,07405942 0,10145126 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,07405942 0,10139088 ! viral genome replication GO:0019079 29 22 0,000 0,07405942 0,10133056 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07405942 0,10127032 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07405942 0,10121014 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07405942 0,10115004 ! molting cycle process GO:0022404 40 22 0,000 0,07405942 0,10109001 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,07405942 0,10103005 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07405942 0,10097017 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07405942 0,10091035 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,07405942 0,10085061 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,07405942 0,10079093 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,07405942 0,10073133 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,07405942 0,10067179 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,07405942 0,10061233 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,07405942 0,10055294 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07405942 0,10049361 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,07405942 0,10043436 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,07405942 0,10037518 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07405942 0,10031606 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,07405942 0,10025702 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07405942 0,10019804 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07405942 0,10013914 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07405942 0,1000803 ! blastocyst development GO:0001824 37 22 0,000 0,07405942 0,10002153 ! neural tube closure GO:0001843 33 22 0,000 0,07405942 0,09996284 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,07405942 0,09990421 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,07729438 0,10420696 ! neuron fate commitment GO:0048663 32 23 0,000 0,07729438 0,10414592 ! embryonic pattern specification GO:0009880 31 23 0,000 0,07729438 0,10408494 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,07729438 0,10402404 ! myelination GO:0042552 35 23 0,000 0,07729438 0,1039632 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,07729438 0,10390244 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,07729438 0,10384175 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,07729438 0,10378113 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,07729438 0,10372058 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,07729438 0,1036601 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,07729438 0,1035997 ! vesicle targeting GO:0006903 32 23 0,000 0,07729438 0,10353936 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,07729438 0,10347909 ! osteoblast differentiation GO:0001649 40 23 0,000 0,07729438 0,10341889 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,07729438 0,10335877 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,07729438 0,10329871 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,07729438 0,10323872 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,07729438 0,1031788 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,07729438 0,10311895 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,07729438 0,10305918 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,07729438 0,10299947 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,07729438 0,10293982 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,07729438 0,10288025 ! cell fate determination GO:0001709 45 23 0,000 0,07729438 0,10282075 ! pentose metabolic process GO:0019321 31 23 0,000 0,07729438 0,10276132 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,07729438 0,10270195 ! spermatid development GO:0007286 33 23 0,000 0,07729438 0,10264265 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,07729438 0,10258343 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,07729438 0,10252427 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,07729438 0,10246517 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,07729438 0,10240615 ! telomere organization GO:0032200 32 23 0,000 0,07729438 0,10234719 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,07729438 0,10228831 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,07729438 0,10222949 ! regulation of amine transport GO:0051952 38 23 0,000 0,07729438 0,10217073 ! liver development GO:0001889 40 23 0,000 0,07729438 0,10211205 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08051822 0,10630994 ! initiation of viral infection GO:0019059 42 24 0,000 0,08051822 0,10624895 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08051822 0,10618802 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,08051822 0,10612717 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08051822 0,10606639 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08051822 0,10600567 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,08051822 0,10594503 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08051822 0,10588445 ! sperm motility GO:0030317 27 24 0,000 0,08051822 0,10582395 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,08051822 0,10576351 ! vacuole organization GO:0007033 39 24 0,000 0,08051822 0,10570315 ! receptor metabolic process GO:0043112 37 24 0,000 0,08051822 0,10564285 ! neural crest cell development GO:0014032 39 24 0,000 0,08051822 0,10558262 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,08051822 0,10552246 ! primary neural tube formation GO:0014020 35 24 0,000 0,08051822 0,10546236 ! negative regulation of cell development GO:0010721 56 24 0,000 0,08051822 0,10540234 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08051822 0,10534238 ! base-excision repair GO:0006284 31 24 0,000 0,08051822 0,1052825 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08051822 0,10522268 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,08051822 0,10516293 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,08051822 0,10510324 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08051822 0,10504363 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08051822 0,10498408 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,08373098 0,1091112 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,08373098 0,10904941 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,08373098 0,1089877 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,08373098 0,10892605 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,08373098 0,10886448 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,08373098 0,10880297 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,08373098 0,10874154 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 43 25 0,000 0,08373098 0,10868017 ! male gonad development GO:0008584 33 25 0,000 0,08373098 0,10861887 ! iron ion homeostasis GO:0055072 39 25 0,000 0,08373098 0,10855765 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,08373098 0,10849649 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,08373098 0,1084354 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,08373098 0,10837437 ! phospholipid transport GO:0015914 35 25 0,000 0,08373098 0,10831342 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,08373098 0,10825254 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,08373098 0,10819172 ! detection of light stimulus GO:0009583 30 25 0,000 0,08373098 0,10813097 ! leukocyte proliferation GO:0070661 39 25 0,000 0,08373098 0,10807029 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,08373098 0,10800968 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,0869327 0,11207692 ! translational initiation GO:0006413 43 26 0,000 0,0869327 0,11201413 ! regulation of pH GO:0006885 36 26 0,000 0,0869327 0,11195141 ! circadian rhythm GO:0007623 42 26 0,000 0,0869327 0,11188876 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,0869327 0,11182618 ! post-embryonic development GO:0009791 42 26 0,000 0,0869327 0,11176368 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,0869327 0,11170124 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,0869327 0,11163887 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,0869327 0,11157657 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,0869327 0,11151434 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,0869327 0,11145218 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,0869327 0,11139009 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09012342 0,11541418 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09012342 0,11534995 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09012342 0,11528579 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09012342 0,11522171 ! catechol metabolic process GO:0009712 43 27 0,000 0,09012342 0,1151577 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09012342 0,11509376 ! acute-phase response GO:0006953 42 27 0,000 0,09012342 0,11502989 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09012342 0,11496609 ! myofibril assembly GO:0030239 36 27 0,000 0,09012342 0,11490236 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09012342 0,1148387 ! response to ionizing radiation GO:0010212 47 27 0,000 0,09012342 0,11477512 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09012342 0,1147116 ! natural killer cell activation GO:0030101 35 27 0,000 0,09012342 0,11464815 ! lipid oxidation GO:0034440 38 27 0,000 0,09012342 0,11458478 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09012342 0,11452147 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,09012342 0,11445823 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09012342 0,11439507 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,09012342 0,11433197 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09012342 0,11426894 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,09012342 0,11420598 ! gene silencing GO:0016458 41 27 0,000 0,09012342 0,11414309 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,09330316 0,11810527 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,09330316 0,11804031 ! phenol metabolic process GO:0018958 44 28 0,000 0,09330316 0,11797541 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,09330316 0,11791059 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,09330316 0,11784584 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,09330316 0,11778116 ! cell junction assembly GO:0034329 56 28 0,000 0,09330316 0,11771655 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,09330316 0,11765202 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,09330316 0,11758755 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,09330316 0,11752315 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,09330316 0,11745883 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,09330316 0,11739457 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,09330316 0,11733039 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,09330316 0,11726627 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,09330316 0,11720223 ! mesoderm formation GO:0001707 46 28 0,000 0,09330316 0,11713825 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,09330316 0,11707435 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,09330316 0,11701051 ! ensheathment of neurons GO:0007272 43 28 0,000 0,09330316 0,11694674 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,09330316 0,11688305 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,09330316 0,11681942 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,09330316 0,11675586 ! neural tube formation GO:0001841 41 28 0,000 0,09330316 0,11669237 ! placenta development GO:0001890 37 28 0,000 0,09330316 0,11662895 ! regulation of B cell activation GO:0050864 42 28 0,000 0,09330316 0,1165656 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,09647198 0,12045904 ! regulation of innate immune response GO:0045088 38 29 0,000 0,09647198 0,12039368 ! ovulation cycle process GO:0022602 41 29 0,000 0,09647198 0,12032839 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,09647198 0,12026317 ! protein targeting to membrane GO:0006612 53 29 0,000 0,09647198 0,12019802 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,09647198 0,12013295 ! mismatch repair GO:0006298 34 29 0,000 0,09647198 0,12006794 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,09647198 0,120003 ! muscle cell development GO:0055001 38 29 0,000 0,09647198 0,11993814 ! formation of primary germ layer GO:0001704 48 29 0,000 0,09647198 0,11987334 ! telencephalon development GO:0021537 52 29 0,000 0,09647198 0,11980861 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,09647198 0,11974396 ! eye morphogenesis GO:0048592 51 29 0,000 0,09647198 0,11967937 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,09647198 0,11961485 ! tissue homeostasis GO:0001894 42 29 0,000 0,09647198 0,1195504 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,0996299 0,12339729 ! collagen metabolic process GO:0032963 40 30 0,000 0,0996299 0,12333088 ! organic anion transport GO:0015711 51 30 0,000 0,0996299 0,12326454 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,0996299 0,12319826 ! spliceosome assembly GO:0000245 49 30 0,000 0,0996299 0,12313206 ! spindle organization GO:0007051 37 30 0,000 0,0996299 0,12306594 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,0996299 0,12299988 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,0996299 0,12293389 ! ceramide metabolic process GO:0006672 43 30 0,000 0,0996299 0,12286797 ! ovulation cycle GO:0042698 43 30 0,000 0,0996299 0,12280213 ! hindbrain development GO:0030902 45 30 0,000 0,0996299 0,12273635 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,0996299 0,12267065 ! adult locomotory behavior GO:0008344 47 30 0,000 0,0996299 0,12260501 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,0996299 0,12253945 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,0996299 0,12247396 ! response to heat GO:0009408 41 30 0,000 0,0996299 0,12240853 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,0996299 0,12234318 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,0996299 0,12227789 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,10277697 0,12607308 ! negative regulation of secretion GO:0051048 49 31 0,000 0,10277697 0,12600587 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,10277697 0,12593874 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,10277697 0,12587168 ! odontogenesis GO:0042476 50 31 0,000 0,10277697 0,12580469 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,10277697 0,12573778 ! segmentation GO:0035282 41 31 0,000 0,10277697 0,12567093 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,10277697 0,12560416 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,10277697 0,12553745 ! metanephros development GO:0001656 58 31 0,000 0,10277697 0,12547082 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,10277697 0,12540426 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,10277697 0,12533776 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,10277697 0,12527134 ! RNA modification GO:0009451 40 31 0,000 0,10277697 0,12520499 ! regulation of muscle development GO:0048634 48 32 0,000 0,10591321 0,12895732 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,10591321 0,12888909 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,10591321 0,12882093 ! meiosis I GO:0007127 52 32 0,000 0,10591321 0,12875285 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,10591321 0,12868483 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,10591321 0,12861689 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,10591321 0,12854902 ! peripheral nervous system development GO:0007422 53 32 0,000 0,10591321 0,12848121 ! regulation of protein stability GO:0031647 48 32 0,000 0,10591321 0,12841349 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,10591321 0,12834583 ! cytokine production GO:0001816 44 32 0,000 0,10591321 0,12827824 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,10591321 0,12821073 ! vesicle localization GO:0051648 47 32 0,000 0,10591321 0,12814328 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,10903867 0,13185539 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,10903867 0,1317861 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,10903867 0,13171688 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,10903867 0,13164774 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,10903867 0,13157867 ! sister chromatid segregation GO:0000819 46 33 0,000 0,10903867 0,13150967 ! ear morphogenesis GO:0042471 42 33 0,000 0,10903867 0,13144075 ! actomyosin structure organization GO:0031032 43 33 0,000 0,10903867 0,13137189 ! cell junction organization GO:0034330 63 33 0,000 0,10903867 0,13130311 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,10903867 0,1312344 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,10903867 0,13116577 ! nucleus organization GO:0006997 49 33 0,000 0,10903867 0,1310972 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,10903867 0,13102871 ! female gonad development GO:0008585 49 33 0,000 0,10903867 0,13096028 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,10903867 0,13089193 ! positive regulation of cell development GO:0010720 54 33 0,000 0,10903867 0,13082365 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,10903867 0,13075545 ! regulation of proteolysis GO:0030162 50 33 0,000 0,10903867 0,13068731 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,10903867 0,13061924 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,10903867 0,13055125 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,10903867 0,13048332 ! cytokinesis GO:0000910 52 33 0,000 0,10903867 0,13041547 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,10903867 0,13034768 ! mRNA catabolic process GO:0006402 48 34 0,000 0,11215338 0,13400145 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,11215338 0,13393187 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,11215338 0,13386237 ! feeding behavior GO:0007631 45 34 0,000 0,11215338 0,13379294 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,11215338 0,13372358 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,11215338 0,13365429 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,11215338 0,13358508 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,11215338 0,13351593 ! neuron migration GO:0001764 46 34 0,000 0,11215338 0,13344686 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,11215338 0,13337786 ! female gamete generation GO:0007292 43 34 0,000 0,11215338 0,13330893 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,11215338 0,13324008 ! polyol metabolic process GO:0019751 44 34 0,000 0,11215338 0,13317129 ! aerobic respiration GO:0009060 47 34 0,000 0,11215338 0,13310257 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,11215338 0,13303393 ! embryonic organ development GO:0048568 45 34 0,000 0,11215338 0,13296535 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,11215338 0,13289685 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,11525739 0,13650463 ! Notch signaling pathway GO:0007219 56 35 0,000 0,11525739 0,13643438 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,11525739 0,13636419 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,11525739 0,13629408 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,11525739 0,13622405 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,11525739 0,13615408 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,11525739 0,13608418 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,11525739 0,13601436 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,11525739 0,13594461 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,11525739 0,13587493 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,11525739 0,13580532 ! glycogen metabolic process GO:0005977 48 35 0,000 0,11525739 0,13573579 ! pigment metabolic process GO:0042440 61 35 0,000 0,11525739 0,13566632 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,11525739 0,13559693 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,11835072 0,13916495 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,11835072 0,13909384 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,11835072 0,1390228 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,11835072 0,13895184 ! negative regulation of binding GO:0051100 58 36 0,000 0,11835072 0,13888094 ! neural tube development GO:0021915 50 36 0,000 0,11835072 0,13881012 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,11835072 0,13873937 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,11835072 0,13866869 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,11835072 0,13859809 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,11835072 0,13852756 ! glucan metabolic process GO:0044042 49 36 0,000 0,11835072 0,13845709 GO:0006073|cellular glucan metabolic process, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,12143341 0,14199127 ! learning GO:0007612 67 37 0,000 0,12143341 0,14191912 ! ion transmembrane transport GO:0034220 56 37 0,000 0,12143341 0,14184705 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,12143341 0,14177504 ! regulation of protein secretion GO:0050708 51 37 0,000 0,12143341 0,14170311 ! amino acid activation GO:0043038 52 37 0,000 0,12143341 0,14163125 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,12143341 0,14155947 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,12450549 0,14506719 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,12450549 0,14499374 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,12450549 0,14492036 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,12450549 0,14484706 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,12450549 0,14477383 ! phagocytosis GO:0006909 60 38 0,000 0,12450549 0,14470067 ! mesenchymal cell development GO:0014031 64 38 0,000 0,12450549 0,14462759 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,12450549 0,14455459 ! maintenance of location in cell GO:0051651 69 38 0,000 0,12450549 0,14448165 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,12756701 0,14795972 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,12756701 0,14788515 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,12756701 0,14781065 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,12756701 0,14773622 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,12756701 0,14766187 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,12756701 0,14758759 ! male sex differentiation GO:0046661 53 39 0,000 0,12756701 0,14751339 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,12756701 0,14743926 ! chromatin remodeling GO:0006338 68 39 0,000 0,12756701 0,14736521 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,12756701 0,14729123 ! JNK cascade GO:0007254 54 39 0,000 0,12756701 0,14721733 ! synapse organization GO:0050808 55 39 0,000 0,12756701 0,1471435 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,130618 0,15058717 ! response to calcium ion GO:0051592 58 40 0,000 0,130618 0,15051173 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,130618 0,15043636 ! regulation of tube size GO:0035150 60 40 0,000 0,130618 0,15036107 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,130618 0,15028585 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,130618 0,1502107 ! peptide metabolic process GO:0006518 56 40 0,000 0,130618 0,15013564 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,130618 0,15006064 ! inner ear development GO:0048839 57 40 0,000 0,130618 0,14998573 ! T cell differentiation GO:0030217 65 40 0,000 0,130618 0,14991088 ! double-strand break repair GO:0006302 67 40 0,000 0,130618 0,14983611 ! B cell differentiation GO:0030183 62 40 0,000 0,130618 0,14976142 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,130618 0,1496868 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,130618 0,14961226 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,130618 0,14953778 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,130618 0,14946339 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,1336585 0,15286651 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,1336585 0,15279053 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,1336585 0,15271463 ! glucose transport GO:0015758 52 41 0,000 0,1336585 0,1526388 ! endosome transport GO:0016197 71 41 0,000 0,1336585 0,15256305 ! striated muscle contraction GO:0006941 62 41 0,000 0,1336585 0,15248737 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,1336585 0,15241177 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,1336585 0,15233625 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,1336585 0,15226079 ! biopolymer methylation GO:0043414 62 41 0,000 0,1336585 0,15218542 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,1336585 0,15211012 ! mitochondrial transport GO:0006839 60 42 0,000 0,13668853 0,15548152 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,13668853 0,15540466 ! cellular component disassembly GO:0022411 64 42 0,000 0,13668853 0,15532788 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,13668853 0,15525117 ! hexose transport GO:0008645 54 42 0,000 0,13668853 0,15517454 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,13668853 0,15509799 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,13668853 0,15502151 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,13668853 0,15494511 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,13668853 0,15486878 ! positive regulation of binding GO:0051099 59 43 0,000 0,13970814 0,15821208 ! neuromuscular process GO:0050905 79 43 0,000 0,13970814 0,15813422 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,13970814 0,15805643 ! tRNA processing GO:0008033 49 43 0,000 0,13970814 0,15797873 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,13970814 0,15790109 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,13970814 0,15782354 ! methylation GO:0032259 64 43 0,000 0,13970814 0,15774606 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,14271736 0,16106474 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,14271736 0,16098575 ! glycolysis GO:0006096 53 44 0,000 0,14271736 0,16090683 ! regulation of action potential GO:0001508 71 44 0,000 0,14271736 0,16082799 ! regulation of ion transport GO:0043269 57 44 0,000 0,14271736 0,16074923 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,14271736 0,16067055 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,14271736 0,16059195 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,14271736 0,16051342 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,14271736 0,16043496 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,14271736 0,16035659 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,14271736 0,16027829 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,14271736 0,16020007 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,14271736 0,16012192 ! RNA catabolic process GO:0006401 64 45 0,000 0,14571623 0,16340679 ! positive regulation of defense response GO:0031349 59 45 0,000 0,14571623 0,16332716 ! regulation of translational initiation GO:0006446 64 45 0,000 0,14571623 0,1632476 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,14571623 0,16316813 ! cell recognition GO:0008037 58 45 0,000 0,14571623 0,16308872 ! cell maturation GO:0048469 60 45 0,000 0,14571623 0,1630094 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,14870478 0,16627175 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,14870478 0,16619096 ! cell redox homeostasis GO:0045454 63 46 0,000 0,14870478 0,16611024 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,14870478 0,16602961 ! regulation of ossification GO:0030278 71 46 0,000 0,14870478 0,16594905 ! histone modification GO:0016570 68 46 0,000 0,14870478 0,16586857 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,14870478 0,16578817 ! viral infectious cycle GO:0019058 71 47 0,000 0,15168304 0,16902665 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,15168304 0,16894479 ! endocrine system development GO:0035270 83 47 0,000 0,15168304 0,16886302 ! covalent chromatin modification GO:0016569 75 47 0,000 0,15168304 0,16878132 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,15168304 0,16869971 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,15168304 0,16861817 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,15168304 0,16853671 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,15168304 0,16845533 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,15168304 0,16837403 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,15168304 0,16829281 ! chloride transport GO:0006821 67 48 0,000 0,15465106 0,1715031 ! response to temperature stimulus GO:0009266 62 48 0,000 0,15465106 0,17142045 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,15465106 0,17133788 ! gastrulation GO:0007369 73 48 0,000 0,15465106 0,17125538 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,15465106 0,17117297 ! regulation of endocytosis GO:0030100 63 48 0,000 0,15465106 0,17109063 ! nuclear export GO:0051168 69 48 0,000 0,15465106 0,17100838 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,15465106 0,1709262 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,15465106 0,17084411 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,15760886 0,17402802 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,15760886 0,17394452 ! sensory perception of smell GO:0007608 61 49 0,000 0,15760886 0,17386109 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,15760886 0,17377774 ! RNA elongation GO:0006354 62 49 0,000 0,15760886 0,17369448 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,15760886 0,17361129 ! germ cell development GO:0007281 68 49 0,000 0,15760886 0,17352818 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,15760886 0,17344515 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,15760886 0,1733622 ! cartilage development GO:0051216 70 49 0,000 0,15760886 0,17327934 ! maintenance of location GO:0051235 84 49 0,000 0,15760886 0,17319655 ! ear development GO:0043583 72 50 0,000 0,16055648 0,17635143 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,16055648 0,17626725 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,16055648 0,17618316 ! proton transport GO:0015992 75 50 0,000 0,16055648 0,17609914 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,16055648 0,1760152 ! positive regulation of secretion GO:0051047 71 51 0,000 0,16349395 0,17915011 ! hydrogen transport GO:0006818 77 51 0,000 0,16349395 0,1790648 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,16349395 0,17897958 ! adult behavior GO:0030534 80 51 0,000 0,16349395 0,17889443 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,16349395 0,17880936 ! transition metal ion transport GO:0000041 74 52 0,000 0,16642131 0,18192444 ! aging GO:0007568 79 52 0,000 0,16642131 0,18183802 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,16642131 0,18175167 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,16642131 0,18166541 ! establishment of organelle localization GO:0051656 85 52 0,000 0,16642131 0,18157923 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,1693386 0,18467462 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,1693386 0,1845871 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,1693386 0,18449966 ! kidney development GO:0001822 90 53 0,000 0,1693386 0,1844123 ! single fertilization GO:0007338 59 53 0,000 0,1693386 0,18432503 ! cell projection assembly GO:0030031 76 53 0,000 0,1693386 0,18423783 ! amino acid transport GO:0006865 84 54 0,000 0,17224584 0,18731227 ! glucose catabolic process GO:0006007 66 54 0,000 0,17224584 0,18722374 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,17224584 0,18713531 ! DNA catabolic process GO:0006308 67 54 0,000 0,17224584 0,18704695 ! detection of external stimulus GO:0009581 66 54 0,000 0,17224584 0,18695868 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,17224584 0,18687049 ! exocytosis GO:0006887 74 55 0,000 0,17514308 0,18992413 ! mesoderm development GO:0007498 76 55 0,000 0,17514308 0,18983463 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,17514308 0,18974521 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,17514308 0,18965588 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,17803034 0,19269166 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,17803034 0,19260102 ! carbohydrate transport GO:0008643 74 57 0,000 0,18090766 0,19562182 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,18090766 0,19552989 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,18090766 0,19543805 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,18090766 0,1953463 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,18090766 0,19525463 ! camera-type eye development GO:0043010 88 57 0,000 0,18090766 0,19516304 ! secondary metabolic process GO:0019748 84 57 0,000 0,18090766 0,19507155 ! developmental maturation GO:0021700 75 57 0,000 0,18090766 0,19498014 ! gonad development GO:0008406 79 57 0,000 0,18090766 0,19488881 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,18377507 0,19788514 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,18377507 0,19779254 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,1866326 0,20077408 ! actin filament organization GO:0007015 95 59 0,000 0,1866326 0,20068022 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,1866326 0,20058644 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,1866326 0,20049276 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,1894803 0,20345691 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,1894803 0,20336196 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,1894803 0,20326711 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,1894803 0,20317235 ! regulation of heart contraction GO:0008016 91 60 0,000 0,1894803 0,20307767 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,1894803 0,20298309 ! fertilization GO:0009566 68 60 0,000 0,1894803 0,20288859 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,19231819 0,20583147 ! meiosis GO:0007126 96 61 0,000 0,19231819 0,20573574 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,19231819 0,20564009 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,19231819 0,20554453 ! urogenital system development GO:0001655 101 61 0,000 0,19231819 0,20544906 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,19231819 0,20535368 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,19231819 0,20525839 ! extracellular matrix organization GO:0030198 103 61 0,000 0,19231819 0,20516319 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,19231819 0,20506807 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,19231819 0,20497305 ! amine catabolic process GO:0009310 90 62 0,000 0,1951463 0,20789092 ! neurotransmitter transport GO:0006836 81 62 0,000 0,1951463 0,20779468 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,1951463 0,20769852 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,1951463 0,20760245 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,1951463 0,20750647 ! meiotic cell cycle GO:0051321 97 62 0,000 0,1951463 0,20741058 ! organelle localization GO:0051640 96 62 0,000 0,1951463 0,20731478 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,19796468 0,2102118 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,19796468 0,21011479 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,19796468 0,21001788 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,20077334 0,21289935 ! negative regulation of cell size GO:0045792 108 64 0,000 0,20077334 0,21280124 ! appendage morphogenesis GO:0035107 93 64 0,000 0,20077334 0,21270322 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,20077334 0,21260529 ! hexose catabolic process GO:0019320 82 64 0,000 0,20077334 0,21250745 ! reproductive structure development GO:0048608 90 65 0,000 0,20357234 0,21537092 ! appendage development GO:0048736 94 65 0,000 0,20357234 0,21527189 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,20357234 0,21517296 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,20357234 0,21507413 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,20357234 0,21497538 ! defense response to bacterium GO:0042742 73 65 0,000 0,20357234 0,21487672 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,20357234 0,21477815 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,20636168 0,21762122 ! antigen processing and presentation GO:0019882 96 66 0,000 0,20636168 0,21752148 ! axon guidance GO:0007411 99 66 0,000 0,20636168 0,21742184 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,20636168 0,21732229 ! regulation of immune effector process GO:0002697 101 66 0,000 0,20636168 0,21722283 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,20914142 0,22004816 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,20914142 0,21994754 ! learning or memory GO:0007611 123 68 0,000 0,21191159 0,22275898 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,21191159 0,22265722 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,21191159 0,22255555 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,21191159 0,22245397 ! rhythmic process GO:0048511 105 68 0,000 0,21191159 0,22235248 ! inorganic anion transport GO:0015698 93 68 0,000 0,21191159 0,22225109 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,2146722 0,22504379 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,2146722 0,22494126 ! response to drug GO:0042493 108 69 0,000 0,2146722 0,22483883 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,2146722 0,22473649 ! response to metal ion GO:0010038 103 70 0,000 0,21742331 0,22751302 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,21742331 0,22740955 ! eye development GO:0001654 111 70 0,000 0,21742331 0,22730619 ! amine transport GO:0015837 101 70 0,000 0,21742331 0,22720291 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,21742331 0,22709973 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,22016493 0,22985899 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,22016493 0,22975469 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,22016493 0,2296505 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,22016493 0,22954639 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,22289711 0,23228969 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,22289711 0,23218449 ! negative regulation of transport GO:0051051 116 73 0,000 0,22561987 0,23491431 ! regulation of blood pressure GO:0008217 107 73 0,000 0,22561987 0,23480801 ! mitochondrion organization GO:0007005 104 73 0,000 0,22561987 0,23470181 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,22561987 0,23459571 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,22561987 0,2344897 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,22833325 0,23720256 ! digestion GO:0007586 97 74 0,000 0,22833325 0,23709547 ! protein import into nucleus GO:0006606 118 74 0,000 0,22833325 0,23698848 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,22833325 0,23688158 ! response to inorganic substance GO:0010035 115 75 0,000 0,23103727 0,23957878 ! negative regulation of growth GO:0045926 123 75 0,000 0,23103727 0,23947081 ! response to nutrient GO:0007584 104 75 0,000 0,23103727 0,23936294 ! regulation of ligase activity GO:0051340 114 75 0,000 0,23103727 0,23925517 ! nuclear import GO:0051170 121 75 0,000 0,23103727 0,23914749 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,23103727 0,23903992 ! amine biosynthetic process GO:0009309 97 76 0,000 0,23373198 0,24171922 ! tRNA metabolic process GO:0006399 95 76 0,000 0,23373198 0,24161059 ! response to unfolded protein GO:0006986 99 76 0,000 0,23373198 0,24150205 ! regulation of protein transport GO:0051223 114 76 0,000 0,23373198 0,2413936 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,2364174 0,24405745 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,2364174 0,24394796 ! regulation of DNA binding GO:0051101 119 77 0,000 0,2364174 0,24383857 ! sex differentiation GO:0007548 105 77 0,000 0,2364174 0,24372927 ! protein ubiquitination GO:0016567 125 77 0,000 0,2364174 0,24362008 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,2364174 0,24351098 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,2364174 0,24340197 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,2364174 0,24329307 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,23909355 0,24593702 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,23909355 0,24582708 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,24176049 0,24845805 ! T cell activation GO:0042110 134 79 0,000 0,24176049 0,24834708 ! regulation of lyase activity GO:0051339 133 79 0,000 0,24176049 0,24823621 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,24176049 0,24812544 ! chromatin assembly GO:0031497 102 80 0,000 0,24441822 0,25074126 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,24441822 0,25062948 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,24441822 0,25051779 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,24441822 0,2504062 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,24441822 0,25029471 ! forebrain development GO:0030900 131 80 0,000 0,24441822 0,25018332 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,2470668 0,25278187 ! response to protein stimulus GO:0051789 111 81 0,000 0,2470668 0,25266947 ! regulation of neurological system process GO:0031644 122 81 0,000 0,2470668 0,25255717 ! vitamin metabolic process GO:0006766 103 81 0,000 0,2470668 0,25244497 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,2470668 0,25233288 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,24970624 0,25491538 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,25233658 0,25748631 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,25233658 0,25737212 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,25233658 0,25725804 ! regulation of defense response GO:0031347 117 84 0,000 0,25495785 0,25981527 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,25495785 0,2597002 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,25495785 0,25958524 ! sterol metabolic process GO:0016125 120 84 0,000 0,25495785 0,25947038 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,25757008 0,26201291 ! rRNA metabolic process GO:0016072 107 85 0,000 0,25757008 0,26189707 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,25757008 0,26178134 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,25757008 0,26166572 ! regulation of protein localization GO:0032880 132 85 0,000 0,25757008 0,26155019 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,2601733 0,26407705 ! cell cycle arrest GO:0007050 150 86 0,000 0,2601733 0,26396056 ! nucleosome organization GO:0034728 114 87 0,000 0,26276754 0,26647502 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,26276754 0,26635758 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,26276754 0,26624024 ! female pregnancy GO:0007565 130 87 0,000 0,26276754 0,26612301 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,26276754 0,26600587 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,26535284 0,26850485 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,26535284 0,26838677 GO:0016054|organic acid catabolic process, ! regulation of neurogenesis GO:0050767 153 89 0,000 0,26792921 0,27087349 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,26792921 0,27075447 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,26792921 0,27063557 ! regulation of T cell activation GO:0050863 128 89 0,000 0,26792921 0,27051676 ! leukocyte differentiation GO:0002521 143 90 0,000 0,2704967 0,27298921 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,2704967 0,27286948 ! hormone metabolic process GO:0042445 121 90 0,000 0,2704967 0,27274985 ! ATP metabolic process GO:0046034 137 91 0,000 0,27305533 0,27520914 ! response to virus GO:0009615 122 91 0,000 0,27305533 0,27508859 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,27560513 0,27753582 ! DNA recombination GO:0006310 146 92 0,000 0,27560513 0,27741436 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,27814614 0,27984957 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,27814614 0,2797272 ! response to oxidative stress GO:0006979 141 94 0,000 0,28067838 0,28215047 ! regulation of binding GO:0051098 151 95 0,000 0,28320188 0,28456283 ! carboxylic acid transport GO:0046942 147 95 0,000 0,28320188 0,28443857 GO:0015849|organic acid transport, ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,28571667 0,28683908 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,28822278 0,28922879 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,28822278 0,28910266 ! extracellular structure organization GO:0043062 156 99 0,000 0,29320909 0,29397598 ! protein import GO:0017038 156 99 0,000 0,29320909 0,29384789 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,29320909 0,29371991 ! regulation of translation GO:0006417 151 100 0,000 0,29568934 0,29607553 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,29568934 0,29594669 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,29568934 0,29581796 ! protein localization in organelle GO:0033365 161 100 0,000 0,29568934 0,29568934