pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1211-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 3,052E-10 7,343E-07 ! fat cell differentiation GO:0045444 50 27 4,000 9,231E-08 1,11E-04 ! regulation of hormone metabolic process GO:0032350 26 12 3,000 1,454E-07 1,166E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 3,000 3,971E-07 2,388E-04 ! carbohydrate homeostasis GO:0033500 53 38 4,000 5,53E-07 2,661E-04 GO:0042593|glucose homeostasis, ! mesenchymal cell development GO:0014031 87 40 4,000 7,201E-07 2,888E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 7,278E-07 2,502E-04 ! pancreas development GO:0031016 35 20 3,000 1,386E-06 4,17E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 1,451E-06 3,879E-04 ! negative regulation of growth GO:0045926 155 84 5,000 1,551E-06 3,731E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 2,532E-06 5,537E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 2,532E-06 5,076E-04 ! negative regulation of cell development GO:0010721 73 25 3,000 3,561E-06 6,591E-04 GO:0050768|negative regulation of neurogenesis, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 3,561E-06 6,12E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 4,038E-06 6,477E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 4,038E-06 6,072E-04 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 2,000 6,038E-06 8,546E-04 ! regulation of homeostatic process GO:0032844 134 62 4,000 6,575E-06 8,789E-04 ! protein sumoylation GO:0016925 15 10 2,000 8,6E-06 1,089E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 8,6E-06 1,035E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 1,179E-05 1,351E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 1,179E-05 1,289E-03 ! androgen receptor signaling pathway GO:0030521 74 36 3,000 1,6E-05 1,674E-03 ! response to hypoxia GO:0001666 171 81 4,000 2,442E-05 2,448E-03 ! response to gamma radiation GO:0010332 28 14 2,000 2,577E-05 2,48E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 2,000 2,577E-05 2,384E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 2,577E-05 2,296E-03 ! response to oxygen levels GO:0070482 176 83 4,000 2,749E-05 2,362E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 3,211E-05 2,664E-03 ! detection of bacterium GO:0016045 18 15 2,000 3,211E-05 2,575E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 3,939E-05 3,058E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 4,29E-05 3,226E-03 ! pigmentation GO:0043473 100 46 3,000 4,29E-05 3,128E-03 ! myoblast differentiation GO:0045445 45 17 2,000 4,769E-05 3,375E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 4,769E-05 3,278E-03 ! cell cycle arrest GO:0007050 213 100 4,000 6,732E-05 4,499E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 6,754E-05 4,392E-03 ! cellular pigmentation GO:0033059 36 19 2,000 6,754E-05 4,276E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 6,754E-05 4,167E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 7,921E-05 4,765E-03 ! cell aging GO:0007569 44 21 2,000 9,213E-05 5,406E-03 ! detection of biotic stimulus GO:0009595 29 21 2,000 9,213E-05 5,278E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 1,002E-04 5,606E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 1,307E-04 7,144E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 1,389E-04 7,427E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 1,482E-04 7,75E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 1,574E-04 8,056E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,575E-04 7,896E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 1,75E-04 8,591E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,75E-04 8,419E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,75E-04 8,254E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,75E-04 8,096E-03 ! microvillus organization GO:0032528 7 5 1,000 1,75E-04 7,943E-03 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 9 5 1,000 1,75E-04 7,796E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 1,75E-04 7,654E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 1,75E-04 7,517E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 1,75E-04 7,385E-03 ! B cell homeostasis GO:0001782 13 5 1,000 1,75E-04 7,258E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 1,75E-04 7,135E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,75E-04 7,016E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,75E-04 6,901E-03 ! receptor biosynthetic process GO:0032800 7 5 1,000 1,75E-04 6,79E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 1,774E-04 6,773E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 1,774E-04 6,667E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 1,882E-04 6,966E-03 ! lung development GO:0030324 144 67 3,000 1,882E-04 6,86E-03 ! mitochondrial membrane organization GO:0007006 57 27 2,000 1,989E-04 7,143E-03 ! response to toxin GO:0009636 47 27 2,000 1,989E-04 7,038E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 1,993E-04 6,95E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 2,109E-04 7,248E-03 ! respiratory tube development GO:0030323 150 70 3,000 2,229E-04 7,555E-03 ! humoral immune response GO:0006959 109 71 3,000 2,355E-04 7,869E-03 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 2,47E-04 8,139E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 2,47E-04 8,029E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 2,485E-04 7,973E-03 ! respiratory system development GO:0060541 153 72 3,000 2,485E-04 7,868E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 2,617E-04 8,178E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 2,617E-04 8,073E-03 ! attachment of GPI anchor to protein GO:0016255 15 6 1,000 2,617E-04 7,971E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,617E-04 7,871E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,617E-04 7,774E-03 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 1,000 2,617E-04 7,679E-03 ! neural nucleus development GO:0048857 14 6 1,000 2,617E-04 7,587E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 2,617E-04 7,497E-03 ! negative regulation of multicellular organism growth GO:0040015 8 6 1,000 2,617E-04 7,408E-03 ! protein deubiquitination GO:0016579 14 6 1,000 2,617E-04 7,322E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,617E-04 7,238E-03 ! negative regulation of axon extension GO:0030517 21 6 1,000 2,617E-04 7,156E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 2,762E-04 7,466E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 3,019E-04 8,072E-03 ! steroid biosynthetic process GO:0006694 131 76 3,000 3,059E-04 8,089E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 3,321E-04 8,686E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 3,548E-04 9,179E-03 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 3,642E-04 9,323E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 3,654E-04 9,254E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,654E-04 9,158E-03 ! mRNA stabilization GO:0048255 18 7 1,000 3,654E-04 9,063E-03 GO:0043489|RNA stabilization, ! lipoprotein transport GO:0042953 14 7 1,000 3,654E-04 8,971E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 3,654E-04 8,88E-03 ! organ growth GO:0035265 15 7 1,000 3,654E-04 8,792E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,654E-04 8,705E-03 ! eating behavior GO:0042755 7 7 1,000 3,654E-04 8,619E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 3,654E-04 8,536E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 3,654E-04 8,453E-03 ! response to tumor cell GO:0002347 13 7 1,000 3,654E-04 8,373E-03 ! axonal fasciculation GO:0007413 18 7 1,000 3,654E-04 8,294E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 3,654E-04 8,216E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 3,654E-04 8,14E-03 ! protein modification by small protein removal GO:0070646 16 7 1,000 3,654E-04 8,066E-03 ! protein import into nucleus GO:0006606 158 80 3,000 3,723E-04 8,143E-03 ! nuclear import GO:0051170 161 81 3,000 3,903E-04 8,461E-03 ! regulation of neuron differentiation GO:0045664 167 81 3,000 3,903E-04 8,385E-03 ! placenta development GO:0001890 53 34 2,000 3,982E-04 8,48E-03 ! response to drug GO:0042493 143 82 3,000 4,09E-04 8,633E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 4,859E-04 0,01016497 ! hemoglobin metabolic process GO:0020027 13 8 1,000 4,859E-04 0,01007735 ! pigment granule organization GO:0048753 16 8 1,000 4,859E-04 9,991E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,859E-04 9,907E-03 ! glycine catabolic process GO:0006546 13 8 1,000 4,859E-04 9,823E-03 ! ER overload response GO:0006983 12 8 1,000 4,859E-04 9,741E-03 ! regulation of pigmentation during development GO:0048070 24 8 1,000 4,859E-04 9,661E-03 ! melanin metabolic process GO:0006582 15 8 1,000 4,859E-04 9,582E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 4,859E-04 9,504E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 4,859E-04 9,427E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 4,859E-04 9,352E-03 ! response to UV-B GO:0010224 16 8 1,000 4,859E-04 9,278E-03 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 4,859E-04 9,205E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 4,859E-04 9,133E-03 ! tube morphogenesis GO:0035239 176 86 3,000 4,902E-04 9,143E-03 ! protein localization in nucleus GO:0034504 176 87 3,000 5,122E-04 9,479E-03 ! tissue remodeling GO:0048771 76 37 2,000 5,124E-04 9,41E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 5,124E-04 9,339E-03 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 5,582E-04 0,01009751 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 6,229E-04 0,01118517 ! induction of positive chemotaxis GO:0050930 15 9 1,000 6,229E-04 0,01110232 ! regulation of glycolysis GO:0006110 21 9 1,000 6,229E-04 0,01102069 ! keratinocyte proliferation GO:0043616 14 9 1,000 6,229E-04 0,01094024 ! T cell selection GO:0045058 23 9 1,000 6,229E-04 0,01086097 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 6,229E-04 0,01078283 ! behavioral fear response GO:0001662 22 9 1,000 6,229E-04 0,01070581 GO:0002209|behavioral defense response, ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 6,229E-04 0,01062988 ! gas homeostasis GO:0033483 16 9 1,000 6,229E-04 0,01055502 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 6,229E-04 0,01048121 ! induction of an organ GO:0001759 14 9 1,000 6,229E-04 0,01040843 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 6,229E-04 0,01033664 ! regulation of hormone secretion GO:0046883 62 40 2,000 6,455E-04 0,01063784 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 6,589E-04 0,01078408 ! T cell differentiation GO:0030217 81 41 2,000 6,943E-04 0,01128783 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 7,138E-04 0,01152572 ! leukocyte differentiation GO:0002521 202 96 3,000 7,424E-04 0,01190802 ! response to reactive oxygen species GO:0000302 67 42 2,000 7,455E-04 0,01187808 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 7,455E-04 0,01179993 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 7,765E-04 0,0122114 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 7,765E-04 0,0121321 ! lung alveolus development GO:0048286 26 10 1,000 7,765E-04 0,01205383 ! B cell proliferation GO:0042100 18 10 1,000 7,765E-04 0,01197656 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 7,765E-04 0,01190028 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 7,765E-04 0,01182496 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 7,765E-04 0,01175059 ! regulation of bone resorption GO:0045124 25 10 1,000 7,765E-04 0,01167715 ! regulation of gliogenesis GO:0014013 23 10 1,000 7,765E-04 0,01160462 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 1,000 7,765E-04 0,01153299 ! negative regulation of axonogenesis GO:0050771 32 10 1,000 7,765E-04 0,01146223 ! apical protein localization GO:0045176 15 10 1,000 7,765E-04 0,01139234 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 7,765E-04 0,0113233 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 7,765E-04 0,01125508 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 7,765E-04 0,01118769 ! response to nicotine GO:0035094 20 10 1,000 7,765E-04 0,01112109 ! interphase GO:0051325 213 98 3,000 8,021E-04 0,01141874 ! skeletal muscle tissue development GO:0007519 186 99 3,000 8,331E-04 0,0117913 GO:0060538|skeletal muscle organ development, ! B cell differentiation GO:0030183 107 44 2,000 8,547E-04 0,01202644 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 9,13E-04 0,01277129 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 9,13E-04 0,01269747 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 9,465E-04 0,01308752 ! blood vessel remodeling GO:0001974 29 11 1,000 9,465E-04 0,01301274 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 9,465E-04 0,0129388 ! regulation of intracellular pH GO:0051453 19 11 1,000 9,465E-04 0,0128657 ! negative regulation of ossification GO:0030279 26 11 1,000 9,465E-04 0,01279342 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 9,465E-04 0,01272195 ! nitric oxide metabolic process GO:0046209 15 11 1,000 9,465E-04 0,01265127 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 1,000 9,465E-04 0,01258137 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 24 11 1,000 9,465E-04 0,01251225 ! regulation of leukocyte migration GO:0002685 26 11 1,000 9,465E-04 0,01244387 ! oocyte differentiation GO:0009994 18 11 1,000 9,465E-04 0,01237624 ! thymus development GO:0048538 27 11 1,000 9,465E-04 0,01230935 ! developmental induction GO:0031128 19 11 1,000 9,465E-04 0,01224317 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 9,465E-04 0,01217769 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 9,737E-04 0,01246126 ! response to insulin stimulus GO:0032868 95 46 2,000 9,737E-04 0,01239532 ! mitochondrial transport GO:0006839 82 48 2,000 1,103E-03 0,01396288 ! activation of caspase activity GO:0006919 84 48 2,000 1,103E-03 0,01388977 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 1,133E-03 0,01419341 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,133E-03 0,01411987 ! cartilage condensation GO:0001502 20 12 1,000 1,133E-03 0,01404709 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 1,133E-03 0,01397505 GO:0050927|positive regulation of positive chemotaxis, ! protein complex disassembly GO:0043241 27 12 1,000 1,133E-03 0,01390375 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 1,000 1,133E-03 0,01383317 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,133E-03 0,01376331 ! focal adhesion formation GO:0048041 35 12 1,000 1,133E-03 0,01369414 ! mitotic spindle organization GO:0007052 21 12 1,000 1,133E-03 0,01362567 ! asymmetric protein localization GO:0008105 20 12 1,000 1,133E-03 0,01355788 ! fear response GO:0042596 26 12 1,000 1,133E-03 0,01349077 ! histone acetylation GO:0016573 26 12 1,000 1,133E-03 0,01342431 ! gland morphogenesis GO:0022612 29 12 1,000 1,133E-03 0,0133585 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,133E-03 0,01329334 ! T cell homeostasis GO:0043029 25 12 1,000 1,133E-03 0,01322881 ! spleen development GO:0048536 22 12 1,000 1,133E-03 0,0131649 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,133E-03 0,01310161 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,133E-03 0,01303892 ! regulation of cell shape GO:0008360 125 51 2,000 1,315E-03 0,01507137 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 1,315E-03 0,01499994 ! regulation of chemokine production GO:0032642 18 13 1,000 1,335E-03 0,01514967 ! endocrine pancreas development GO:0031018 22 13 1,000 1,335E-03 0,01507855 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,335E-03 0,01500809 ! response to X-ray GO:0010165 25 13 1,000 1,335E-03 0,01493828 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,335E-03 0,01486912 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 1,335E-03 0,0148006 ! regulation of cellular pH GO:0030641 22 13 1,000 1,335E-03 0,01473271 ! ribosomal large subunit biogenesis GO:0042273 13 13 1,000 1,335E-03 0,01466544 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,335E-03 0,01459878 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,335E-03 0,01453272 ! embryonic placenta development GO:0001892 23 13 1,000 1,335E-03 0,01446726 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,392E-03 0,01501561 ! cartilage development GO:0051216 90 52 2,000 1,392E-03 0,01494858 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 2,000 1,471E-03 0,01572679 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 1,471E-03 0,0156572 ! response to UV GO:0009411 104 53 2,000 1,471E-03 0,01558823 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,553E-03 0,01638898 ! hair follicle morphogenesis GO:0031069 26 14 1,000 1,553E-03 0,01631741 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 1,553E-03 0,01624647 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 1,553E-03 0,01617614 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 1,553E-03 0,01610641 ! regulation of RNA stability GO:0043487 32 14 1,000 1,553E-03 0,01603728 ! regulation of axon extension GO:0030516 37 14 1,000 1,553E-03 0,01596875 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,637E-03 0,01676008 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 1,637E-03 0,01668907 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 1,637E-03 0,01661865 ! regulation of actin filament length GO:0030832 105 56 2,000 1,724E-03 0,01743206 ! skeletal muscle fiber development GO:0048741 111 56 2,000 1,724E-03 0,01735913 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,787E-03 0,01791532 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,787E-03 0,01784099 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,787E-03 0,01776726 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,787E-03 0,01769415 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 1,787E-03 0,01762163 ! muscle maintenance GO:0046716 26 15 1,000 1,787E-03 0,01754971 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,787E-03 0,01747837 ! regulation of bone remodeling GO:0046850 137 57 2,000 1,815E-03 0,01767583 ! muscle fiber development GO:0048747 112 57 2,000 1,815E-03 0,01760456 ! regulation of tissue remodeling GO:0034103 140 58 2,000 1,908E-03 0,01843371 ! positive regulation of secretion GO:0051047 95 59 2,000 2,004E-03 0,01928442 ! regulation of cellular component size GO:0032535 109 59 2,000 2,004E-03 0,01920759 ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 2,004E-03 0,01913137 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,037E-03 0,01936908 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 2,037E-03 0,01929282 ! axon cargo transport GO:0008088 43 16 1,000 2,037E-03 0,01921716 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,037E-03 0,0191421 ! DNA replication initiation GO:0006270 27 16 1,000 2,037E-03 0,01906761 ! neuron recognition GO:0008038 35 16 1,000 2,037E-03 0,01899371 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,037E-03 0,01892037 ! defense response to virus GO:0051607 37 16 1,000 2,037E-03 0,0188476 ! metencephalon development GO:0022037 30 17 1,000 2,302E-03 0,02122016 ! limbic system development GO:0021761 36 17 1,000 2,302E-03 0,02113917 ! adult walking behavior GO:0007628 33 17 1,000 2,302E-03 0,02105879 ! heart looping GO:0001947 30 17 1,000 2,302E-03 0,02097902 ! regulation of viral genome replication GO:0045069 28 17 1,000 2,302E-03 0,02089986 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 2,302E-03 0,02082129 ! glycine metabolic process GO:0006544 28 17 1,000 2,302E-03 0,0207433 ! regulation of protein binding GO:0043393 33 17 1,000 2,302E-03 0,0206659 ! neural crest cell migration GO:0001755 37 17 1,000 2,302E-03 0,02058908 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 2,302E-03 0,02051282 ! detection of external stimulus GO:0009581 91 63 2,000 2,418E-03 0,02146686 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,583E-03 0,02284416 ! patterning of blood vessels GO:0001569 39 18 1,000 2,583E-03 0,02276048 ! epidermis morphogenesis GO:0048730 40 18 1,000 2,583E-03 0,02267742 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,583E-03 0,02259495 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,583E-03 0,02251309 ! long-chain fatty acid transport GO:0015909 31 18 1,000 2,583E-03 0,02243181 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,583E-03 0,02235112 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 2,878E-03 0,02482261 ! lipid phosphorylation GO:0046834 35 19 1,000 2,878E-03 0,02473396 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 2,878E-03 0,02464593 ! pigmentation during development GO:0048066 41 19 1,000 2,878E-03 0,02455854 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 2,878E-03 0,02447176 ! adaptive immune response GO:0002250 119 67 2,000 2,881E-03 0,02441055 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell cycle checkpoint GO:0000075 137 69 2,000 3,132E-03 0,02644218 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,189E-03 0,02683158 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,189E-03 0,02673809 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 3,189E-03 0,02664525 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 3,189E-03 0,02655305 ! cellular response to starvation GO:0009267 33 20 1,000 3,189E-03 0,02646149 ! peptidyl-serine modification GO:0018209 43 20 1,000 3,189E-03 0,02637056 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 3,189E-03 0,02628025 ! B cell activation GO:0042113 160 71 2,000 3,396E-03 0,02788649 ! ovarian follicle development GO:0001541 35 21 1,000 3,515E-03 0,02876963 ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 3,515E-03 0,0286721 ! oogenesis GO:0048477 36 21 1,000 3,515E-03 0,02857524 ! DNA modification GO:0006304 34 21 1,000 3,515E-03 0,02847903 ! positive regulation of locomotion GO:0040017 39 21 1,000 3,515E-03 0,02838346 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to cytokine stimulus GO:0034097 63 21 1,000 3,515E-03 0,02828853 ! gut development GO:0048565 39 21 1,000 3,515E-03 0,02819424 ! phosphoinositide metabolic process GO:0030384 128 72 2,000 3,533E-03 0,02823917 ! regulation of actin cytoskeleton organization GO:0032956 149 74 2,000 3,817E-03 0,0304059 ! microtubule-based transport GO:0010970 54 22 1,000 3,856E-03 0,03062215 ! regulation of chemotaxis GO:0050920 40 22 1,000 3,856E-03 0,03052142 ! regeneration GO:0031099 41 22 1,000 3,856E-03 0,03042135 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 3,856E-03 0,03032193 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 3,856E-03 0,03022316 ! ureteric bud development GO:0001657 43 22 1,000 3,856E-03 0,03012503 ! renal system process GO:0003014 41 22 1,000 3,856E-03 0,03002754 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,856E-03 0,02993068 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 3,856E-03 0,02983444 ! cell-matrix adhesion GO:0007160 163 75 2,000 3,963E-03 0,03056423 ! lymphocyte differentiation GO:0030098 167 75 2,000 3,963E-03 0,03046658 ! regulation of catabolic process GO:0009894 161 76 2,000 4,114E-03 0,03152128 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 4,212E-03 0,03217219 ! viral genome replication GO:0019079 41 23 1,000 4,212E-03 0,03207038 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 4,212E-03 0,03196921 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 4,212E-03 0,03186868 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,212E-03 0,03176878 ! barbed-end actin filament capping GO:0051016 50 23 1,000 4,212E-03 0,0316695 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,212E-03 0,03157084 ! regulation of viral reproduction GO:0050792 38 23 1,000 4,212E-03 0,03147279 ! fatty acid transport GO:0015908 44 23 1,000 4,212E-03 0,03137536 ! regulation of actin filament-based process GO:0032970 152 77 2,000 4,267E-03 0,03169002 ! protein oligomerization GO:0051259 139 78 2,000 4,425E-03 0,03275614 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 4,582E-03 0,03381948 ! multicellular organismal response to stress GO:0033555 49 24 1,000 4,582E-03 0,03371606 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 4,582E-03 0,03361326 ! regulation of behavior GO:0050795 43 24 1,000 4,582E-03 0,0335111 ! lymphocyte proliferation GO:0046651 48 24 1,000 4,582E-03 0,03340955 ! pallium development GO:0021543 49 24 1,000 4,582E-03 0,03330861 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,582E-03 0,03320828 ! leukocyte homeostasis GO:0001776 44 24 1,000 4,582E-03 0,03310856 ! protein tetramerization GO:0051262 52 24 1,000 4,582E-03 0,03300943 ! muscle cell differentiation GO:0042692 159 80 2,000 4,749E-03 0,03411107 ! T cell activation GO:0042110 168 81 2,000 4,917E-03 0,0352101 ! cell-substrate adhesion GO:0031589 171 81 2,000 4,917E-03 0,03510562 ! vasculogenesis GO:0001570 46 25 1,000 4,967E-03 0,03535779 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,967E-03 0,03525349 ! negative regulation of DNA replication GO:0008156 42 25 1,000 4,967E-03 0,03514981 ! receptor metabolic process GO:0043112 46 25 1,000 4,967E-03 0,03504673 ! response to starvation GO:0042594 42 25 1,000 4,967E-03 0,03494425 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 4,967E-03 0,03484237 ! neural crest cell development GO:0014032 54 25 1,000 4,967E-03 0,03474109 GO:0014033|neural crest cell differentiation, ! somitogenesis GO:0001756 43 25 1,000 4,967E-03 0,03464039 ! cellular response to nutrient levels GO:0031669 41 25 1,000 4,967E-03 0,03454027 ! response to nutrient GO:0007584 125 82 2,000 5,088E-03 0,03528094 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 5,088E-03 0,03517956 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 5,366E-03 0,03699509 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 5,366E-03 0,03688939 ! molting cycle process GO:0022404 50 26 1,000 5,366E-03 0,03678429 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 1,000 5,366E-03 0,03667979 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 5,366E-03 0,03657588 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 5,366E-03 0,03647256 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 5,366E-03 0,03636982 ! leukocyte proliferation GO:0070661 52 26 1,000 5,366E-03 0,03626766 GO:0032943|mononuclear cell proliferation, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,78E-03 0,03895211 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 5,78E-03 0,03884331 ! iron ion transport GO:0006826 59 27 1,000 5,78E-03 0,03873511 ! protein amino acid acylation GO:0043543 55 27 1,000 5,78E-03 0,03862751 ! male gonad development GO:0008584 44 27 1,000 5,78E-03 0,03852051 ! base-excision repair GO:0006284 41 27 1,000 5,78E-03 0,0384141 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 5,78E-03 0,03830828 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 5,78E-03 0,03820303 ! mitochondrion organization GO:0007005 148 86 2,000 5,809E-03 0,03829061 ! regulation of DNA binding GO:0051101 155 88 2,000 6,191E-03 0,04069707 ! gland development GO:0048732 206 88 2,000 6,191E-03 0,04058618 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 6,207E-03 0,04058284 ! dendrite development GO:0016358 59 28 1,000 6,207E-03 0,04047286 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,207E-03 0,04036348 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 6,207E-03 0,04025468 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 6,207E-03 0,04014647 ! regulation of cell adhesion GO:0030155 212 89 2,000 6,387E-03 0,04120074 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 6,649E-03 0,04277201 ! regulation of pH GO:0006885 43 29 1,000 6,649E-03 0,04265795 ! complement activation, classical pathway GO:0006958 48 29 1,000 6,649E-03 0,0425445 ! response to organic cyclic substance GO:0014070 55 29 1,000 6,649E-03 0,04243165 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 6,649E-03 0,0423194 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 6,649E-03 0,04220773 ! tissue homeostasis GO:0001894 48 29 1,000 6,649E-03 0,04209666 GO:0048871|multicellular organismal homeostasis, ! cell junction assembly GO:0034329 78 30 1,000 7,104E-03 0,04486179 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 7,104E-03 0,04474436 ! response to heat GO:0009408 50 30 1,000 7,104E-03 0,04462753 ! collagen metabolic process GO:0032963 45 31 1,000 7,573E-03 0,04745059 ! GPI anchor biosynthetic process GO:0006506 53 31 1,000 7,573E-03 0,04732734 ! ovulation cycle process GO:0022602 49 31 1,000 7,573E-03 0,04720473 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 7,573E-03 0,04708276 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 7,573E-03 0,04696141 ! detection of stimulus GO:0051606 151 96 2,000 7,867E-03 0,04865742 ! response to hydrogen peroxide GO:0042542 50 32 1,000 8,056E-03 0,04969869 ! GPI anchor metabolic process GO:0006505 56 32 1,000 8,056E-03 0,04957158 ! spindle organization GO:0007051 46 32 1,000 8,056E-03 0,04944512 ! metanephros development GO:0001656 74 32 1,000 8,056E-03 0,04931931 ! regulation of axonogenesis GO:0050770 75 32 1,000 8,056E-03 0,04919413 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 8,056E-03 0,04906959 ! ovulation cycle GO:0042698 51 32 1,000 8,056E-03 0,04894568 ! hindbrain development GO:0030902 61 32 1,000 8,056E-03 0,04882239 ! positive regulation of catabolic process GO:0009896 64 32 1,000 8,056E-03 0,04869972 ! regulation of protein localization GO:0032880 176 97 2,000 8,093E-03 0,04880338 ! DNA damage checkpoint GO:0000077 71 33 1,000 8,552E-03 0,05144108 ! post-embryonic development GO:0009791 69 33 1,000 8,552E-03 0,0513128 ! cell fate specification GO:0001708 52 33 1,000 8,552E-03 0,05118516 ! leukocyte chemotaxis GO:0030595 50 33 1,000 8,552E-03 0,05105815 GO:0060326|cell chemotaxis, ! adult locomotory behavior GO:0008344 59 33 1,000 8,552E-03 0,05093176 ! xenobiotic metabolic process GO:0006805 51 34 1,000 9,062E-03 0,05383351 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 9,062E-03 0,05370092 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 9,062E-03 0,05356898 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 9,062E-03 0,05343768 ! regulation of muscle development GO:0048634 70 35 1,000 9,585E-03 0,05638293 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 9,585E-03 0,05624541 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 9,585E-03 0,05610856 ! female gonad development GO:0008585 58 35 1,000 9,585E-03 0,05597238 ! telencephalon development GO:0021537 68 35 1,000 9,585E-03 0,05583685 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 9,585E-03 0,05570198 ! neural tube formation GO:0001841 67 35 1,000 9,585E-03 0,05556776 ! cell junction organization GO:0034330 86 36 1,000 0,01012065 0,05853434 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01012065 0,05839397 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01012065 0,05825427 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01012065 0,05811524 ! embryonic organ development GO:0048568 57 36 1,000 0,01012065 0,05797687 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,0106697 0,06097693 ! regulation of protein stability GO:0031647 73 37 1,000 0,0106697 0,06083244 ! pigment metabolic process GO:0042440 80 37 1,000 0,0106697 0,06068863 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,01123165 0,0637343 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 1,000 0,01123165 0,06358434 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,01123165 0,06343508 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01123165 0,06328652 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01123165 0,06313865 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 1,000 0,01123165 0,06299148 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01123165 0,06284498 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,01123165 0,06269917 ! mammary gland development GO:0030879 86 39 1,000 0,01180639 0,06575502 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01180639 0,06560316 ! segmentation GO:0035282 67 39 1,000 0,01180639 0,065452 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,01180639 0,06530154 ! feeding behavior GO:0007631 59 40 1,000 0,0123938 0,06839332 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,0123938 0,06823681 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01299377 0,07137676 ! female gamete generation GO:0007292 61 41 1,000 0,01299377 0,07121417 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,01299377 0,07105232 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01360619 0,07423241 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01360619 0,07406446 ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,01360619 0,07389727 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,01360619 0,07373084 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01360619 0,07356515 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01423093 0,07677047 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01423093 0,07659872 ! neural tube development GO:0021915 77 43 1,000 0,01423093 0,07642774 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01423093 0,07625752 ! male sex differentiation GO:0046661 76 44 1,000 0,0148679 0,07949368 ! double-strand break repair GO:0006302 81 44 1,000 0,0148679 0,07931742 ! biopolymer methylation GO:0043414 84 44 1,000 0,0148679 0,07914194 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,0148679 0,07896723 ! developmental growth GO:0048589 82 44 1,000 0,0148679 0,0787933 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,01551696 0,08205233 ! leukocyte migration GO:0050900 68 45 1,000 0,01551696 0,08187239 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01617802 0,08517355 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,01617802 0,08498758 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01617802 0,08480242 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01617802 0,08461807 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01685096 0,08794664 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01685096 0,08775628 ! methylation GO:0032259 90 47 1,000 0,01685096 0,08756674 ! protein homooligomerization GO:0051260 76 47 1,000 0,01685096 0,08737802 ! cellular component disassembly GO:0022411 86 48 1,000 0,01753567 0,09073293 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,01753567 0,09053823 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,01823204 0,09393208 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01823204 0,09373137 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,01823204 0,09353152 ! response to temperature stimulus GO:0009266 76 49 1,000 0,01823204 0,09333251 ! endocrine system development GO:0035270 104 49 1,000 0,01823204 0,09313436 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01823204 0,09293704 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,01823204 0,09274055 GO:0019724|B cell mediated immunity, ! regulation of cell projection organization GO:0031344 121 50 1,000 0,01893996 0,09613828 ! neuromuscular process GO:0050905 99 50 1,000 0,01893996 0,09593588 ! regulation of ossification GO:0030278 117 50 1,000 0,01893996 0,09573434 ! histone modification GO:0016570 91 50 1,000 0,01893996 0,09553364 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01893996 0,09533378 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,01893996 0,09513475 ! positive regulation of binding GO:0051099 78 51 1,000 0,01965933 0,09854238 ! viral infectious cycle GO:0019058 99 51 1,000 0,01965933 0,09833751 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01965933 0,09813349 ! chromatin remodeling GO:0006338 109 51 1,000 0,01965933 0,09793032 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,01965933 0,09772798 ! vesicle organization GO:0016050 107 51 1,000 0,01965933 0,09752648 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,02039003 0,10094325 ! positive regulation of growth GO:0045927 90 52 1,000 0,02039003 0,10073597 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02039003 0,10052955 ! amino acid activation GO:0043038 92 52 1,000 0,02039003 0,10032396 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02090874 0,10266619 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02090874 0,10245709 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02090874 0,10224884 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02090874 0,10204144 ! neuron fate determination GO:0048664 7 5 0,000 0,02090874 0,10183488 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02090874 0,10162915 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02090874 0,10142426 ! polyol transport GO:0015791 12 5 0,000 0,02090874 0,10122018 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02090874 0,10101693 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02090874 0,10081449 ! response to superoxide GO:0000303 10 5 0,000 0,02090874 0,10061286 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02090874 0,10041204 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02090874 0,10021201 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02090874 0,10001279 ! female meiosis GO:0007143 7 5 0,000 0,02090874 0,09981435 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02090874 0,0996167 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02090874 0,09941982 ! cobalt ion transport GO:0006824 11 5 0,000 0,02090874 0,09922373 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02090874 0,09902841 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02090874 0,09883385 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02090874 0,09864006 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02090874 0,09844703 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02090874 0,09825475 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02090874 0,09806322 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02090874 0,09787243 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02090874 0,09768239 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02090874 0,09749308 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02090874 0,09730451 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02090874 0,09711666 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02090874 0,09692954 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02090874 0,09674314 ! negative chemotaxis GO:0050919 14 5 0,000 0,02090874 0,09655745 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02090874 0,09637247 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02090874 0,0961882 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02090874 0,09600464 ! behavioral response to pain GO:0048266 9 5 0,000 0,02090874 0,09582177 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02090874 0,0956396 ! Notch receptor processing GO:0007220 8 5 0,000 0,02090874 0,09545812 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02090874 0,09527733 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02090874 0,09509722 ! micturition GO:0060073 9 5 0,000 0,02090874 0,09491779 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02090874 0,09473904 ! copulation GO:0007620 9 5 0,000 0,02090874 0,09456096 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02090874 0,09438355 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02090874 0,0942068 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02090874 0,09403071 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02090874 0,09385528 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02090874 0,0936805 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02090874 0,09350638 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02090874 0,0933329 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02090874 0,09316006 ! grooming behavior GO:0007625 6 5 0,000 0,02090874 0,09298786 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02090874 0,09281629 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02090874 0,09264536 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02090874 0,09247506 ! response to protozoan GO:0001562 10 5 0,000 0,02090874 0,09230538 ! lymph vessel development GO:0001945 10 5 0,000 0,02090874 0,09213632 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02090874 0,09196788 ! endochondral ossification GO:0001958 16 5 0,000 0,02090874 0,09180006 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02090874 0,09163284 ! parathyroid gland development GO:0060017 13 5 0,000 0,02090874 0,09146624 ! anagen GO:0042640 6 5 0,000 0,02090874 0,09130024 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02090874 0,09113484 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02090874 0,09097004 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02090874 0,09080583 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02090874 0,09064222 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02090874 0,09047919 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02090874 0,09031675 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02090874 0,09015489 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02090874 0,08999362 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02090874 0,08983291 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02090874 0,08967278 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02090874 0,08951322 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02090874 0,08935423 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02090874 0,0891958 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02090874 0,08903793 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02090874 0,08888062 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02090874 0,08872386 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02090874 0,08856766 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02090874 0,08841201 ! histidine catabolic process GO:0006548 6 5 0,000 0,02090874 0,0882569 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02090874 0,08810233 ! valine metabolic process GO:0006573 10 5 0,000 0,02090874 0,08794831 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02090874 0,08779482 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02090874 0,08764187 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02090874 0,08748945 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02090874 0,08733755 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02090874 0,08718619 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02090874 0,08703535 ! polyol catabolic process GO:0046174 7 5 0,000 0,02090874 0,08688503 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02090874 0,08673523 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02090874 0,08658594 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02090874 0,08643717 ! muscle cell migration GO:0014812 8 5 0,000 0,02090874 0,0862889 ! mitochondrial fission GO:0000266 8 5 0,000 0,02090874 0,08614115 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02090874 0,0859939 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02090874 0,08584715 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02090874 0,0857009 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02090874 0,08555515 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02090874 0,0854099 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02090874 0,08526514 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02090874 0,08512086 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02090874 0,08497708 ! response to food GO:0032094 6 5 0,000 0,02090874 0,08483378 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02090874 0,08469096 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02090874 0,08454862 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02090874 0,08440676 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02090874 0,08426538 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02090874 0,08412447 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02090874 0,08398403 ! forebrain neuron development GO:0021884 13 5 0,000 0,02090874 0,08384405 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02090874 0,08370454 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02090874 0,0835655 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02090874 0,08342692 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02090874 0,08328879 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02090874 0,08315113 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02090874 0,08301391 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02090874 0,08287715 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02090874 0,08274084 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02090874 0,08260498 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02090874 0,08246956 ! basic amino acid transport GO:0015802 11 5 0,000 0,02090874 0,08233458 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02090874 0,08220005 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02090874 0,08206596 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02090874 0,0819323 ! depyrimidination GO:0045008 10 5 0,000 0,02090874 0,08179907 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02090874 0,08166628 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02090874 0,08153392 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02090874 0,08140199 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02090874 0,08127049 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02090874 0,0811394 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02090874 0,08100875 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02090874 0,08087851 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02090874 0,08074869 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02090874 0,08061928 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02090874 0,08049029 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02090874 0,08036171 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02090874 0,08023354 ! response to arsenic GO:0046685 10 5 0,000 0,02090874 0,08010578 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02090874 0,07997843 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02090874 0,07985148 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02090874 0,07972493 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02090874 0,07959878 ! response to cadmium ion GO:0046686 7 5 0,000 0,02090874 0,07947303 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02090874 0,07934768 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02090874 0,07922273 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02090874 0,07909816 ! decidualization GO:0046697 11 5 0,000 0,02090874 0,07897399 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02090874 0,07885021 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02090874 0,07872681 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02090874 0,0786038 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02090874 0,07848117 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02090874 0,07835893 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02090874 0,07823706 ! neural tube patterning GO:0021532 7 5 0,000 0,02090874 0,07811558 ! embryonic cleavage GO:0040016 6 5 0,000 0,02090874 0,07799447 ! peroxisome fission GO:0016559 5 5 0,000 0,02090874 0,07787373 ! histone demethylation GO:0016577 10 5 0,000 0,02090874 0,07775337 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02090874 0,07763338 ! mitotic recombination GO:0006312 9 5 0,000 0,02090874 0,07751376 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02090874 0,07739451 ! metaphase plate congression GO:0051310 7 5 0,000 0,02090874 0,07727562 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02090874 0,0771571 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02090874 0,07703894 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02090874 0,07692115 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02090874 0,07680371 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02090874 0,07668663 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02090874 0,07656991 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02090874 0,07645354 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02090874 0,07633753 ! plasminogen activation GO:0031639 5 5 0,000 0,02090874 0,07622187 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02090874 0,07610655 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02090874 0,07599159 ! metaphase GO:0051323 8 5 0,000 0,02090874 0,07587697 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02090874 0,0757627 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02090874 0,07564877 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02090874 0,07553518 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02090874 0,07542194 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02090874 0,07530903 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02090874 0,07519646 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02090874 0,07508423 ! response to redox state GO:0051775 5 5 0,000 0,02090874 0,07497233 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02090874 0,07486076 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02090874 0,07474953 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02090874 0,07463862 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02090874 0,07452805 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02090874 0,0744178 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02090874 0,07430787 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02090874 0,07419828 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02090874 0,074089 ! striatum development GO:0021756 9 5 0,000 0,02090874 0,07398005 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02090874 0,07387141 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02090874 0,0737631 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02090874 0,0736551 ! glial cell migration GO:0008347 11 5 0,000 0,02090874 0,07354741 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02090874 0,07344005 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02090874 0,07333299 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02090874 0,07322625 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02090874 0,07311981 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02090874 0,07301369 ! neuroprotection GO:0043526 6 5 0,000 0,02090874 0,07290787 ! neural plate development GO:0001840 8 5 0,000 0,02090874 0,07280236 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02090874 0,07269715 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02090874 0,07259225 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02090874 0,07248765 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02090874 0,07238335 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02090874 0,07227935 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02090874 0,07217565 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02090874 0,07207225 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02090874 0,07196914 ! spindle assembly GO:0051225 6 5 0,000 0,02090874 0,07186633 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02090874 0,07176381 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02090874 0,07166158 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 6 5 0,000 0,02090874 0,07155965 ! stem cell division GO:0017145 11 5 0,000 0,02090874 0,071458 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02090874 0,07135664 ! organ regeneration GO:0031100 7 5 0,000 0,02090874 0,07125557 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02090874 0,07115478 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02090874 0,07105428 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02090874 0,07095406 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,02113197 0,07161058 ! cell maturation GO:0048469 100 53 1,000 0,02113197 0,07150986 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,02113197 0,07140943 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,02188502 0,07385045 ! cell recognition GO:0008037 85 54 1,000 0,02188502 0,07374702 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,0226491 0,07621502 ! heart morphogenesis GO:0003007 97 55 1,000 0,0226491 0,07610857 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,0226491 0,07600242 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02342409 0,07849354 ! regulation of DNA replication GO:0006275 101 56 1,000 0,02342409 0,07838437 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,02420989 0,08090139 ! lipid modification GO:0030258 97 57 1,000 0,02420989 0,08078918 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02420989 0,08067728 ! adult behavior GO:0030534 99 58 1,000 0,0250064 0,08321631 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02503814 0,08320687 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02503814 0,0830921 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02503814 0,08297765 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02503814 0,08286351 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02503814 0,08274969 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02503814 0,08263618 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02503814 0,08252298 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02503814 0,08241009 ! sleep GO:0030431 13 6 0,000 0,02503814 0,08229751 ! response to oxygen radical GO:0000305 11 6 0,000 0,02503814 0,08218523 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02503814 0,08207326 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02503814 0,0819616 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02503814 0,08185024 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02503814 0,08173918 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02503814 0,08162842 ! forebrain regionalization GO:0021871 8 6 0,000 0,02503814 0,08151796 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02503814 0,0814078 ! male meiosis GO:0007140 7 6 0,000 0,02503814 0,08129794 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02503814 0,08118838 ! response to zinc ion GO:0010043 9 6 0,000 0,02503814 0,08107911 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02503814 0,08097013 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02503814 0,08086144 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02503814 0,08075305 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02503814 0,08064495 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02503814 0,08053713 ! malate metabolic process GO:0006108 11 6 0,000 0,02503814 0,08042961 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02503814 0,08032237 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02503814 0,08021541 ! protein refolding GO:0042026 15 6 0,000 0,02503814 0,08010874 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02503814 0,08000236 ! opsonization GO:0008228 8 6 0,000 0,02503814 0,07989625 ! mating behavior GO:0007617 7 6 0,000 0,02503814 0,07979043 ! neuron remodeling GO:0016322 15 6 0,000 0,02503814 0,07968489 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02503814 0,07957962 ! equilibrioception GO:0050957 14 6 0,000 0,02503814 0,07947464 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02503814 0,07936993 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02503814 0,07926549 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02503814 0,07916133 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02503814 0,07905745 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02503814 0,07895383 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02503814 0,07885049 ! toxin metabolic process GO:0009404 11 6 0,000 0,02503814 0,07874742 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02503814 0,07864462 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02503814 0,07854208 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02503814 0,07843981 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02503814 0,07833781 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02503814 0,07823607 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02503814 0,0781346 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02503814 0,07803339 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02503814 0,07793244 ! thymic T cell selection GO:0045061 12 6 0,000 0,02503814 0,07783175 ! protein lipoylation GO:0009249 10 6 0,000 0,02503814 0,07773132 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02503814 0,07763115 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02503814 0,07753124 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02503814 0,07743159 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02503814 0,07733219 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02503814 0,07723305 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02503814 0,07713416 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02503814 0,07703552 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02503814 0,07693713 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02503814 0,076839 ! hyperosmotic response GO:0006972 9 6 0,000 0,02503814 0,07674111 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02503814 0,07664348 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02503814 0,07654609 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02503814 0,07644895 ! urea metabolic process GO:0019627 7 6 0,000 0,02503814 0,07635206 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02503814 0,07625541 ! neutrophil activation GO:0042119 8 6 0,000 0,02503814 0,07615901 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02503814 0,07606285 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02503814 0,07596693 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02503814 0,07587125 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02503814 0,07577582 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02503814 0,07568062 ! neuron apoptosis GO:0051402 9 6 0,000 0,02503814 0,07558567 ! nucleoside salvage GO:0043174 9 6 0,000 0,02503814 0,07549095 GO:0006166|purine ribonucleoside salvage, ! T cell mediated immunity GO:0002456 16 6 0,000 0,02503814 0,07539646 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02503814 0,07530222 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02503814 0,07520821 ! carnitine transport GO:0015879 10 6 0,000 0,02503814 0,07511443 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02503814 0,07502089 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02503814 0,07492758 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02503814 0,0748345 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02503814 0,07474166 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02503814 0,07464904 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02503814 0,07455665 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02503814 0,07446449 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02503814 0,07437256 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02503814 0,07428086 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02503814 0,07418938 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02503814 0,07409812 ! response to UV-C GO:0010225 11 6 0,000 0,02503814 0,07400709 ! astrocyte development GO:0014002 15 6 0,000 0,02503814 0,07391629 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02503814 0,0738257 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02503814 0,07373534 ! interaction with symbiont GO:0051702 13 6 0,000 0,02503814 0,0736452 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02503814 0,07355528 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02503814 0,07346558 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02503814 0,0733761 ! response to copper ion GO:0046688 10 6 0,000 0,02503814 0,07328683 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02503814 0,07319778 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02503814 0,07310895 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02503814 0,07302033 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02503814 0,07293193 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02503814 0,07284374 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02503814 0,07275577 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02503814 0,072668 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02503814 0,07258045 ! hair follicle maturation GO:0048820 7 6 0,000 0,02503814 0,07249311 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02503814 0,07240598 ! Schwann cell development GO:0014044 15 6 0,000 0,02503814 0,07231906 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02503814 0,07223234 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02503814 0,07214584 ! subpallium development GO:0021544 10 6 0,000 0,02503814 0,07205954 ! histone ubiquitination GO:0016574 8 6 0,000 0,02503814 0,07197345 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02503814 0,07188756 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02503814 0,07180188 ! G2 phase GO:0051319 16 6 0,000 0,02503814 0,0717164 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02503814 0,07163112 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02503814 0,07154605 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02503814 0,07146118 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02503814 0,07137651 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02503814 0,07129204 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02503814 0,07120777 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02503814 0,0711237 ! receptor internalization GO:0031623 10 6 0,000 0,02503814 0,07103983 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02503814 0,07095615 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02503814 0,07087268 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02503814 0,0707894 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02503814 0,07070631 ! protein destabilization GO:0031648 9 6 0,000 0,02503814 0,07062342 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02503814 0,07054072 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02503814 0,07045822 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02503814 0,07037591 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02503814 0,07029379 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02503814 0,07021186 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02503814 0,07013012 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02503814 0,07004858 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02503814 0,06996722 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02503814 0,06988605 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02503814 0,06980507 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02503814 0,06972428 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02503814 0,06964367 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02503814 0,06956325 ! catecholamine transport GO:0051937 9 6 0,000 0,02503814 0,06948302 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02503814 0,06940297 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02503814 0,0693231 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02503814 0,06924342 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02503814 0,06916392 ! maternal placenta development GO:0001893 12 6 0,000 0,02503814 0,0690846 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02503814 0,06900547 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02503814 0,06892652 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02503814 0,06884774 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02503814 0,06876915 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02503814 0,06869074 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02503814 0,0686125 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02503814 0,06853444 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02581351 0,07057647 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,02581351 0,07049636 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,02663112 0,07264679 ! kidney development GO:0001822 122 60 1,000 0,02663112 0,07256451 ! glycerophospholipid biosynthetic process GO:0046474 105 61 1,000 0,02745913 0,07473604 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,02745913 0,07465159 ! ear development GO:0043583 103 62 1,000 0,02829744 0,07684383 ! viral reproductive process GO:0022415 126 62 1,000 0,02829744 0,0767572 ! gonad development GO:0008406 98 62 1,000 0,02829744 0,07667076 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,02914595 0,07888093 ! tRNA transcription GO:0009304 14 7 0,000 0,02915027 0,07880398 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02915027 0,07871554 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02915027 0,07862729 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02915027 0,07853924 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02915027 0,07845139 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02915027 0,07836374 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02915027 0,07827628 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02915027 0,07818901 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02915027 0,07810194 ! prostate gland development GO:0030850 13 7 0,000 0,02915027 0,07801507 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02915027 0,07792838 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02915027 0,07784189 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02915027 0,07775559 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02915027 0,07766948 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02915027 0,07758357 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02915027 0,07749784 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02915027 0,0774123 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02915027 0,07732695 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02915027 0,07724179 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02915027 0,07715681 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02915027 0,07707203 ! glycolipid transport GO:0046836 10 7 0,000 0,02915027 0,07698743 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02915027 0,07690301 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02915027 0,07681878 ! neuron adhesion GO:0007158 12 7 0,000 0,02915027 0,07673473 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02915027 0,07665087 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02915027 0,07656719 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02915027 0,07648369 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02915027 0,07640038 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02915027 0,07631724 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02915027 0,07623429 ! pericardium development GO:0060039 14 7 0,000 0,02915027 0,07615151 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02915027 0,07606892 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02915027 0,07598651 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02915027 0,07590427 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02915027 0,07582221 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02915027 0,07574033 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02915027 0,07565862 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02915027 0,0755771 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02915027 0,07549574 ! rhythmic behavior GO:0007622 15 7 0,000 0,02915027 0,07541456 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02915027 0,07533356 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02915027 0,07525273 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02915027 0,07517207 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02915027 0,07509159 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02915027 0,07501128 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02915027 0,07493114 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02915027 0,07485117 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02915027 0,07477137 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02915027 0,07469174 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02915027 0,07461228 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02915027 0,07453299 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02915027 0,07445387 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02915027 0,07437491 ! spinal cord patterning GO:0021511 13 7 0,000 0,02915027 0,07429613 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02915027 0,07421751 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02915027 0,07413905 ! adrenal gland development GO:0030325 17 7 0,000 0,02915027 0,07406077 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02915027 0,07398264 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02915027 0,07390468 ! ovulation GO:0030728 9 7 0,000 0,02915027 0,07382689 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02915027 0,07374926 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02915027 0,07367179 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02915027 0,07359449 ! microtubule nucleation GO:0007020 20 7 0,000 0,02915027 0,07351734 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02915027 0,07344036 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02915027 0,07336354 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02915027 0,07328688 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02915027 0,07321038 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02915027 0,07313404 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02915027 0,07305786 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02915027 0,07298184 ! galactose metabolic process GO:0006012 13 7 0,000 0,02915027 0,07290597 ! vesicle fusion GO:0006906 17 7 0,000 0,02915027 0,07283026 ! response to dietary excess GO:0002021 8 7 0,000 0,02915027 0,07275471 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02915027 0,07267932 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02915027 0,07260408 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02915027 0,072529 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02915027 0,07245408 ! purine salvage GO:0043101 10 7 0,000 0,02915027 0,0723793 ! nucleoside transport GO:0015858 8 7 0,000 0,02915027 0,07230469 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02915027 0,07223022 ! parturition GO:0007567 14 7 0,000 0,02915027 0,07215591 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02915027 0,07208175 ! rRNA modification GO:0000154 14 7 0,000 0,02915027 0,07200775 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02915027 0,07193389 ! spindle checkpoint GO:0031577 15 7 0,000 0,02915027 0,07186019 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02915027 0,07178664 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02915027 0,07171324 ! macrophage differentiation GO:0030225 11 7 0,000 0,02915027 0,07163998 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02915027 0,07156688 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02915027 0,07149393 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02915027 0,07142112 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02915027 0,07134847 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02915027 0,07127596 ! fibrinolysis GO:0042730 10 7 0,000 0,02915027 0,0712036 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02915027 0,07113138 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02915027 0,07105932 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02915027 0,07098739 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02915027 0,07091562 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02915027 0,07084398 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02915027 0,0707725 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02915027 0,07070115 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02915027 0,07062995 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02915027 0,0705589 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02915027 0,07048798 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02915027 0,07041721 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02915027 0,07034658 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02915027 0,0702761 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02915027 0,07020575 ! regulation of meiosis GO:0040020 12 7 0,000 0,02915027 0,07013554 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02915027 0,07006548 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02915027 0,06999555 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02915027 0,06992577 ! transcription termination GO:0006353 13 7 0,000 0,02915027 0,06985612 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02915027 0,06978661 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02915027 0,06971724 ! anaphase GO:0051322 17 7 0,000 0,02915027 0,06964801 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02915027 0,06957891 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02915027 0,06950996 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02915027 0,06944113 ! diuresis GO:0030146 12 7 0,000 0,02915027 0,06937245 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02915027 0,0693039 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02915027 0,06923548 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02915027 0,0691672 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02915027 0,06909906 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02915027 0,06903105 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02915027 0,06896317 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02915027 0,06889543 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02915027 0,06882782 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02915027 0,06876034 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02915027 0,06869299 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02915027 0,06862578 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02915027 0,06855869 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,02915027 0,06849174 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02915027 0,06842492 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02915027 0,06835823 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02915027 0,06829167 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02915027 0,06822524 ! adult feeding behavior GO:0008343 9 7 0,000 0,02915027 0,06815894 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02915027 0,06809276 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02915027 0,06802672 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02915027 0,0679608 ! muscle adaptation GO:0043500 14 7 0,000 0,02915027 0,06789501 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02915027 0,06782935 ! retina homeostasis GO:0001895 12 7 0,000 0,02915027 0,06776381 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02915027 0,0676984 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02915027 0,06763312 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02915027 0,06756796 ! protein prenylation GO:0018342 18 7 0,000 0,02915027 0,06750293 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02915027 0,06743802 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02915027 0,06737324 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02915027 0,06730858 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,03000455 0,06921472 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,03000455 0,06914843 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,03000455 0,06908225 GO:0048609|reproductive process in a multicellular organism, ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,03087316 0,07101418 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,03087316 0,07094635 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,03087316 0,07087865 ! actin filament organization GO:0007015 148 66 1,000 0,03175167 0,07282605 ! secondary metabolic process GO:0019748 116 66 1,000 0,03175167 0,07275669 ! developmental maturation GO:0021700 116 66 1,000 0,03175167 0,07268747 ! cell projection assembly GO:0030031 120 66 1,000 0,03175167 0,07261837 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,03263999 0,07457913 ! activation of immune response GO:0002253 105 67 1,000 0,03263999 0,07450837 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03324518 0,07581793 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03324518 0,07574613 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,03324518 0,07567447 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03324518 0,07560294 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03324518 0,07553155 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03324518 0,07546029 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03324518 0,07538917 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03324518 0,07531818 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03324518 0,07524733 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03324518 0,07517661 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03324518 0,07510602 ! meiotic prophase I GO:0007128 13 8 0,000 0,03324518 0,07503556 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03324518 0,07496524 ! oligopeptide transport GO:0006857 15 8 0,000 0,03324518 0,07489505 ! UTP metabolic process GO:0046051 8 8 0,000 0,03324518 0,07482499 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03324518 0,07475506 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03324518 0,07468526 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03324518 0,07461559 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03324518 0,07454605 ! succinate metabolic process GO:0006105 14 8 0,000 0,03324518 0,07447664 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03324518 0,07440736 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03324518 0,07433821 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03324518 0,07426918 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03324518 0,07420029 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03324518 0,07413152 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03324518 0,07406288 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03324518 0,07399437 ! reflex GO:0060004 16 8 0,000 0,03324518 0,07392598 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03324518 0,07385772 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03324518 0,07378959 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03324518 0,07372158 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03324518 0,07365369 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03324518 0,07358594 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03324518 0,0735183 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03324518 0,07345079 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03324518 0,07338341 ! histidine metabolic process GO:0006547 16 8 0,000 0,03324518 0,07331614 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03324518 0,073249 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03324518 0,07318199 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03324518 0,07311509 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03324518 0,07304832 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03324518 0,07298167 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03324518 0,07291514 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03324518 0,07284874 ! macrophage activation GO:0042116 12 8 0,000 0,03324518 0,07278245 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03324518 0,07271628 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03324518 0,07265024 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03324518 0,07258431 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03324518 0,07251851 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03324518 0,07245282 ! osteoblast development GO:0002076 16 8 0,000 0,03324518 0,07238725 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03324518 0,0723218 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03324518 0,07225647 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03324518 0,07219126 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03324518 0,07212616 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03324518 0,07206118 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03324518 0,07199632 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03324518 0,07193158 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03324518 0,07186695 ! intermediate filament organization GO:0045109 12 8 0,000 0,03324518 0,07180243 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03324518 0,07173804 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03324518 0,07167376 ! cellular extravasation GO:0045123 12 8 0,000 0,03324518 0,07160959 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03324518 0,07154554 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03324518 0,0714816 ! response to antibiotic GO:0046677 11 8 0,000 0,03324518 0,07141778 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03324518 0,07135407 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03324518 0,07129047 ! DNA topological change GO:0006265 12 8 0,000 0,03324518 0,07122699 ! response to tropane GO:0014073 15 8 0,000 0,03324518 0,07116362 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,03324518 0,07110037 ! melanosome transport GO:0032402 13 8 0,000 0,03324518 0,07103722 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03324518 0,07097419 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03324518 0,07091127 ! mast cell activation GO:0045576 14 8 0,000 0,03324518 0,07084846 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03324518 0,07078576 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03324518 0,07072318 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03324518 0,0706607 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03324518 0,07059833 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03324518 0,07053608 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03324518 0,07047393 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03324518 0,07041189 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03324518 0,07034997 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03324518 0,07028815 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03324518 0,07022644 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03324518 0,07016484 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03324518 0,07010334 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03324518 0,07004195 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03324518 0,06998068 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03324518 0,0699195 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03324518 0,06985844 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03324518 0,06979748 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03324518 0,06973663 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03324518 0,06967588 ! hormone catabolic process GO:0042447 17 8 0,000 0,03324518 0,06961524 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03324518 0,06955471 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03324518 0,06949428 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03324518 0,06943395 ! ATP catabolic process GO:0006200 11 8 0,000 0,03324518 0,06937373 ! blastocyst growth GO:0001832 19 8 0,000 0,03324518 0,06931362 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03324518 0,0692536 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03324518 0,0691937 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03324518 0,06913389 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03324518 0,06907419 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03324518 0,06901459 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03324518 0,0689551 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03324518 0,0688957 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03324518 0,06883641 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03324518 0,06877722 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03324518 0,06871814 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03324518 0,06865915 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03324518 0,06860027 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03324518 0,06854148 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03324518 0,0684828 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03324518 0,06842422 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03324518 0,06836574 ! viral reproduction GO:0016032 134 68 1,000 0,03353802 0,06890902 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,03353802 0,06885023 ! urogenital system development GO:0001655 137 69 1,000 0,03444565 0,07065323 ! glycerolipid biosynthetic process GO:0045017 118 69 1,000 0,03444565 0,07059305 ! antigen processing and presentation GO:0019882 104 69 1,000 0,03444565 0,07053297 ! appendage morphogenesis GO:0035107 135 70 1,000 0,03536281 0,07234942 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 1,000 0,03628938 0,07418203 ! reproductive structure development GO:0048608 113 71 1,000 0,03628938 0,07411906 ! appendage development GO:0048736 136 71 1,000 0,03628938 0,07405619 GO:0060173|limb development, ! acute inflammatory response GO:0002526 113 72 1,000 0,03722528 0,07590172 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03732296 0,07603645 ! axon extension GO:0048675 15 9 0,000 0,03732296 0,07597212 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03732296 0,0759079 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03732296 0,07584379 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03732296 0,07577979 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03732296 0,07571589 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03732296 0,07565211 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03732296 0,07558843 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03732296 0,07552485 ! phosphate transport GO:0006817 19 9 0,000 0,03732296 0,07546139 ! reproductive behavior GO:0019098 19 9 0,000 0,03732296 0,07539803 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03732296 0,07533477 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03732296 0,07527163 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03732296 0,07520858 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03732296 0,07514565 ! GTP metabolic process GO:0046039 9 9 0,000 0,03732296 0,07508282 ! RNA methylation GO:0001510 15 9 0,000 0,03732296 0,07502009 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03732296 0,07495747 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03732296 0,07489495 ! artery development GO:0060840 24 9 0,000 0,03732296 0,07483254 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03732296 0,07477023 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03732296 0,07470803 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03732296 0,07464593 ! chemosensory behavior GO:0007635 20 9 0,000 0,03732296 0,07458393 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03732296 0,07452203 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03732296 0,07446024 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03732296 0,07439855 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03732296 0,07433696 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03732296 0,07427548 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03732296 0,07421409 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03732296 0,07415281 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03732296 0,07409163 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03732296 0,07403054 ! protein targeting to ER GO:0045047 22 9 0,000 0,03732296 0,07396956 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03732296 0,07390868 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03732296 0,0738479 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03732296 0,07378722 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03732296 0,07372664 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03732296 0,07366616 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03732296 0,07360578 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03732296 0,0735455 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03732296 0,07348531 ! mannose metabolic process GO:0006013 13 9 0,000 0,03732296 0,07342522 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03732296 0,07336524 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03732296 0,07330535 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03732296 0,07324555 ! receptor clustering GO:0043113 18 9 0,000 0,03732296 0,07318586 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03732296 0,07312626 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03732296 0,07306676 ! ruffle organization GO:0031529 15 9 0,000 0,03732296 0,07300736 ! retinol metabolic process GO:0042572 18 9 0,000 0,03732296 0,07294805 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03732296 0,07288884 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03732296 0,07282972 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03732296 0,0727707 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03732296 0,07271178 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03732296 0,07265295 ! protein heterooligomerization GO:0051291 16 9 0,000 0,03732296 0,07259422 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03732296 0,07253558 ! segment specification GO:0007379 13 9 0,000 0,03732296 0,07247704 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03732296 0,07241859 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03732296 0,07236023 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03732296 0,07230197 ! response to amine stimulus GO:0014075 13 9 0,000 0,03732296 0,0722438 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03732296 0,07218573 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03732296 0,07212775 ! erythrocyte development GO:0048821 15 9 0,000 0,03732296 0,07206986 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03732296 0,07201207 ! renal water homeostasis GO:0003091 14 9 0,000 0,03732296 0,07195437 ! postreplication repair GO:0006301 22 9 0,000 0,03732296 0,07189676 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03732296 0,07183924 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03732296 0,07178181 ! icosanoid secretion GO:0032309 15 9 0,000 0,03732296 0,07172448 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03732296 0,07166724 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03732296 0,07161009 ! regulation of cell division GO:0051302 15 9 0,000 0,03732296 0,07155303 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03732296 0,07149606 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03732296 0,07143918 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03732296 0,07138239 ! sterol catabolic process GO:0016127 11 9 0,000 0,03732296 0,07132569 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03732296 0,07126909 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03732296 0,07121257 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03732296 0,07115614 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03732296 0,0710998 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03732296 0,07104355 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03732296 0,07098739 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03732296 0,07093132 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03732296 0,07087534 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03732296 0,07081944 ! purine base metabolic process GO:0006144 21 9 0,000 0,03732296 0,07076363 ! pigment granule transport GO:0051904 17 9 0,000 0,03732296 0,07070791 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03732296 0,07065228 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03732296 0,07059674 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03732296 0,07054128 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03732296 0,07048591 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03732296 0,07043063 ! mitochondrion localization GO:0051646 15 9 0,000 0,03732296 0,07037543 ! regulation of blood pressure GO:0008217 125 73 1,000 0,03817042 0,07191701 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,03817042 0,07186074 ! axon guidance GO:0007411 139 73 1,000 0,03817042 0,07180455 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03912469 0,07354219 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 1,000 0,03912469 0,07348478 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,03912469 0,07342746 ! rhythmic process GO:0048511 128 75 1,000 0,04008801 0,07517674 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,04106029 0,07694008 ! defense response to bacterium GO:0042742 89 76 1,000 0,04106029 0,0768802 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04138368 0,07742545 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,04138368 0,07736529 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04138368 0,07730522 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04138368 0,07724525 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04138368 0,07718537 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04138368 0,07712558 ! synapsis GO:0007129 13 10 0,000 0,04138368 0,07706589 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04138368 0,07700629 ! N-glycan processing GO:0006491 20 10 0,000 0,04138368 0,07694678 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04138368 0,07688736 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04138368 0,07682803 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04138368 0,0767688 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04138368 0,07670965 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04138368 0,0766506 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04138368 0,07659164 ! androgen metabolic process GO:0008209 17 10 0,000 0,04138368 0,07653277 ! phospholipid efflux GO:0033700 16 10 0,000 0,04138368 0,07647398 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04138368 0,07641529 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04138368 0,07635669 ! pathogenesis GO:0009405 13 10 0,000 0,04138368 0,07629818 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04138368 0,07623976 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04138368 0,07618143 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04138368 0,07612319 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04138368 0,07606503 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04138368 0,07600697 ! endoderm development GO:0007492 16 10 0,000 0,04138368 0,07594899 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04138368 0,0758911 ! arginine catabolic process GO:0006527 13 10 0,000 0,04138368 0,0758333 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04138368 0,07577559 ! proline metabolic process GO:0006560 13 10 0,000 0,04138368 0,07571797 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04138368 0,07566043 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04138368 0,07560298 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04138368 0,07554562 ! V(D)J recombination GO:0033151 28 10 0,000 0,04138368 0,07548835 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04138368 0,07543116 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04138368 0,07537406 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04138368 0,07531704 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04138368 0,07526011 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04138368 0,07520327 ! multicellular organism growth GO:0035264 18 10 0,000 0,04138368 0,07514651 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04138368 0,07508984 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04138368 0,07503325 ! epithelial cell development GO:0002064 20 10 0,000 0,04138368 0,07497675 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04138368 0,07492034 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04138368 0,07486401 ! macroautophagy GO:0016236 17 10 0,000 0,04138368 0,07480776 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04138368 0,0747516 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04138368 0,07469552 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04138368 0,07463953 ! brain morphogenesis GO:0048854 23 10 0,000 0,04138368 0,07458362 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04138368 0,07452779 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04138368 0,07447205 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04138368 0,07441639 ! response to dsRNA GO:0043331 20 10 0,000 0,04138368 0,07436081 ! DNA ligation GO:0006266 19 10 0,000 0,04138368 0,07430532 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04138368 0,07424991 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04138368 0,07419458 ! melanosome localization GO:0032400 16 10 0,000 0,04138368 0,07413934 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04138368 0,07408417 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04138368 0,07402909 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04138368 0,07397409 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04138368 0,07391917 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04138368 0,07386434 ! mRNA cleavage GO:0006379 17 10 0,000 0,04138368 0,07380958 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04138368 0,07375491 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04138368 0,07370032 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04138368 0,0736458 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04138368 0,07359137 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04138368 0,07353702 ! salivary gland development GO:0007431 27 10 0,000 0,04138368 0,07348275 ! prophase GO:0051324 15 10 0,000 0,04138368 0,07342856 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04138368 0,07337445 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04138368 0,07332042 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04138368 0,07326647 ! midbrain development GO:0030901 13 10 0,000 0,04138368 0,07321259 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04138368 0,0731588 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04138368 0,07310509 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04138368 0,07305145 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04138368 0,07299789 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04138368 0,07294442 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04138368 0,07289102 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04138368 0,07283769 ! detection of calcium ion GO:0005513 23 10 0,000 0,04138368 0,07278445 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04138368 0,07273128 ! blastocyst formation GO:0001825 17 10 0,000 0,04138368 0,0726782 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04138368 0,07262518 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04138368 0,07257225 ! activation of innate immune response GO:0002218 12 10 0,000 0,04138368 0,07251939 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04138368 0,07246661 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04138368 0,07241391 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04138368 0,07236128 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04138368 0,07230873 ! localization within membrane GO:0051668 20 10 0,000 0,04138368 0,07225626 ! blood coagulation GO:0007596 146 78 1,000 0,04303135 0,07507862 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,04303135 0,07502422 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,04303135 0,07496989 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,04402995 0,07665416 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,04402995 0,07659873 ! response to metal ion GO:0010038 140 80 1,000 0,04503714 0,07829433 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0454274 0,07891575 ! respiratory burst GO:0045730 17 11 0,000 0,0454274 0,07885882 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0454274 0,07880196 ! neuron fate specification GO:0048665 17 11 0,000 0,0454274 0,07874519 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0454274 0,07868849 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0454274 0,07863188 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0454274 0,07857535 ! thyroid gland development GO:0030878 26 11 0,000 0,0454274 0,07851891 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0454274 0,07846254 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0454274 0,07840625 ! response to pain GO:0048265 24 11 0,000 0,0454274 0,07835005 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0454274 0,07829392 ! T cell proliferation GO:0042098 26 11 0,000 0,0454274 0,07823788 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0454274 0,07818192 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,0454274 0,07812603 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0454274 0,07807023 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0454274 0,0780145 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0454274 0,07795886 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0454274 0,07790329 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0454274 0,0778478 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0454274 0,0777924 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0454274 0,07773707 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0454274 0,07768182 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0454274 0,07762665 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0454274 0,07757155 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0454274 0,07751654 ! UV protection GO:0009650 19 11 0,000 0,0454274 0,0774616 ! adult heart development GO:0007512 14 11 0,000 0,0454274 0,07740674 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0454274 0,07735196 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0454274 0,07729725 ! temperature homeostasis GO:0001659 17 11 0,000 0,0454274 0,07724263 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0454274 0,07718808 ! regulation of organ growth GO:0046620 13 11 0,000 0,0454274 0,0771336 ! pigment granule localization GO:0051875 20 11 0,000 0,0454274 0,07707921 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0454274 0,07702489 ! vasoconstriction GO:0042310 18 11 0,000 0,0454274 0,07697065 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0454274 0,07691648 ! embryonic axis specification GO:0000578 18 11 0,000 0,0454274 0,07686239 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0454274 0,07680838 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0454274 0,07675444 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0454274 0,07670057 ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0454274 0,07664679 ! zymogen activation GO:0031638 15 11 0,000 0,0454274 0,07659307 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0454274 0,07653944 ! nucleosome positioning GO:0016584 15 11 0,000 0,0454274 0,07648588 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0454274 0,07643239 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0454274 0,07637898 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0454274 0,07632564 ! acid secretion GO:0046717 18 11 0,000 0,0454274 0,07627238 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0454274 0,07621919 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0454274 0,07616608 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0454274 0,07611303 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0454274 0,07606007 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0454274 0,07600718 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,0454274 0,07595436 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0454274 0,07590161 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0454274 0,07584894 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0454274 0,07579634 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0454274 0,07574381 ! embryonic gut development GO:0048566 15 11 0,000 0,0454274 0,07569136 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0454274 0,07563897 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0454274 0,07558667 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0454274 0,07553443 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0454274 0,07548226 ! defense response to fungus GO:0050832 13 11 0,000 0,0454274 0,07543017 ! lysogeny GO:0030069 21 11 0,000 0,0454274 0,07537815 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0454274 0,0753262 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0454274 0,07527432 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0454274 0,07522252 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0454274 0,07517078 ! nucleus localization GO:0051647 19 11 0,000 0,0454274 0,07511912 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0454274 0,07506753 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,04605283 0,07604881 ! hemostasis GO:0007599 158 84 1,000 0,04915007 0,08110773 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04945419 0,08155366 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04945419 0,0814978 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04945419 0,08144202 ! virus-host interaction GO:0019048 29 12 0,000 0,04945419 0,08138631 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04945419 0,08133068 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04945419 0,08127513 ! mating GO:0007618 17 12 0,000 0,04945419 0,08121965 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04945419 0,08116425 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04945419 0,08110892 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04945419 0,08105367 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04945419 0,08099849 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04945419 0,08094339 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04945419 0,08088837 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04945419 0,08083342 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04945419 0,08077854 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04945419 0,08072374 ! drug transport GO:0015893 16 12 0,000 0,04945419 0,08066901 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04945419 0,08061436 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04945419 0,08055978 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04945419 0,08050527 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04945419 0,08045084 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04945419 0,08039648 ! forebrain cell migration GO:0021885 21 12 0,000 0,04945419 0,08034219 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04945419 0,08028798 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04945419 0,08023384 ! entry into host cell GO:0030260 32 12 0,000 0,04945419 0,08017978 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,04945419 0,08012578 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04945419 0,08007186 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04945419 0,08001802 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04945419 0,07996424 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04945419 0,07991054 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04945419 0,07985691 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04945419 0,07980335 ! protein homotetramerization GO:0051289 21 12 0,000 0,04945419 0,07974986 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04945419 0,07969644 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04945419 0,0796431 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04945419 0,07958983 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04945419 0,07953662 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04945419 0,07948349 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04945419 0,07943043 ! cranial nerve development GO:0021545 20 12 0,000 0,04945419 0,07937744 ! fucose catabolic process GO:0019317 22 12 0,000 0,04945419 0,07932453 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04945419 0,07927168 ! histone methylation GO:0016571 26 12 0,000 0,04945419 0,0792189 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04945419 0,07916619 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04945419 0,07911356 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04945419 0,07906099 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04945419 0,07900849 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04945419 0,07895606 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04945419 0,07890371 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04945419 0,07885142 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04945419 0,0787992 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04945419 0,07874705 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04945419 0,07869497 ! response to cold GO:0009409 17 12 0,000 0,04945419 0,07864295 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04945419 0,07859101 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04945419 0,07853913 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,05019891 0,07966924 ! response to inorganic substance GO:0010035 153 86 1,000 0,05125582 0,08129301 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,05232071 0,08292728 ! regulation of protein transport GO:0051223 154 87 1,000 0,05232071 0,08287269 GO:0070201|regulation of establishment of protein localization, ! cGMP metabolic process GO:0046068 18 13 0,000 0,05346414 0,0846281 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05346414 0,08457246 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05346414 0,08451689 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05346414 0,0844614 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05346414 0,08440598 ! lipid localization GO:0010876 28 13 0,000 0,05346414 0,08435063 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05346414 0,08429535 ! organelle fusion GO:0048284 32 13 0,000 0,05346414 0,08424015 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05346414 0,08418502 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05346414 0,08412996 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05346414 0,08407497 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05346414 0,08402006 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05346414 0,08396522 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05346414 0,08391044 ! methionine metabolic process GO:0006555 27 13 0,000 0,05346414 0,08385574 ! plasma membrane organization GO:0007009 24 13 0,000 0,05346414 0,08380111 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05346414 0,08374656 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05346414 0,08369207 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05346414 0,08363765 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05346414 0,08358331 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05346414 0,08352903 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05346414 0,08347483 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05346414 0,08342069 ! exocrine system development GO:0035272 32 13 0,000 0,05346414 0,08336663 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05346414 0,08331264 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05346414 0,08325871 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05346414 0,08320486 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05346414 0,08315107 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05346414 0,08309736 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05346414 0,08304371 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05346414 0,08299014 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05346414 0,08293663 ! ribosome assembly GO:0042255 17 13 0,000 0,05346414 0,08288319 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05346414 0,08282982 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05346414 0,08277652 ! chromatin silencing GO:0006342 26 13 0,000 0,05346414 0,08272329 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05346414 0,08267012 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05346414 0,08261703 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05346414 0,082564 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05346414 0,08251104 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05346414 0,08245815 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05346414 0,08240532 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05346414 0,08235257 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05346414 0,08229988 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05346414 0,08224726 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05346414 0,0821947 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05346414 0,08214222 ! insulin secretion GO:0030073 23 13 0,000 0,05346414 0,0820898 ! actin filament polymerization GO:0030041 24 13 0,000 0,05346414 0,08203744 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05346414 0,08198516 ! acrosome reaction GO:0007340 18 13 0,000 0,05346414 0,08193294 ! ossification GO:0001503 188 90 1,000 0,05556243 0,08509433 ! sex differentiation GO:0007548 145 90 1,000 0,05556243 0,0850402 ! bone development GO:0060348 189 91 1,000 0,05665841 0,08666251 ! response to protein stimulus GO:0051789 149 91 1,000 0,05665841 0,08660745 ! rRNA transcription GO:0009303 25 14 0,000 0,05745729 0,08777286 ! lactation GO:0007595 26 14 0,000 0,05745729 0,08771716 ! reproductive cellular process GO:0048610 20 14 0,000 0,05745729 0,08766154 ! tRNA modification GO:0006400 20 14 0,000 0,05745729 0,08760599 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05745729 0,08755051 ! regulation of S phase GO:0033261 23 14 0,000 0,05745729 0,0874951 ! water transport GO:0006833 21 14 0,000 0,05745729 0,08743975 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05745729 0,08738448 ! non-recombinational repair GO:0000726 25 14 0,000 0,05745729 0,08732928 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05745729 0,08727415 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05745729 0,08721909 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05745729 0,08716409 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05745729 0,08710917 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05745729 0,08705431 ! palate development GO:0060021 31 14 0,000 0,05745729 0,08699953 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05745729 0,08694481 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05745729 0,08689016 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05745729 0,08683558 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05745729 0,08678107 ! arginine metabolic process GO:0006525 17 14 0,000 0,05745729 0,08672663 ! regulation of heart rate GO:0002027 24 14 0,000 0,05745729 0,08667226 ! organic alcohol transport GO:0015850 29 14 0,000 0,05745729 0,08661795 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05745729 0,08656371 ! embryo implantation GO:0007566 30 14 0,000 0,05745729 0,08650954 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05745729 0,08645544 ! L-amino acid transport GO:0015807 30 14 0,000 0,05745729 0,08640141 ! bone mineralization GO:0030282 17 14 0,000 0,05745729 0,08634744 ! stem cell development GO:0048864 43 14 0,000 0,05745729 0,08629354 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05745729 0,08623971 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05745729 0,08618594 ! cerebellum development GO:0021549 21 14 0,000 0,05745729 0,08613224 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05745729 0,08607861 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05745729 0,08602505 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05745729 0,08597155 ! cofactor transport GO:0051181 26 14 0,000 0,05745729 0,08591812 ! NADP metabolic process GO:0006739 24 14 0,000 0,05745729 0,08586475 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05745729 0,08581145 ! intestinal absorption GO:0050892 25 14 0,000 0,05745729 0,08575822 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05745729 0,08570505 ! oxygen transport GO:0015671 21 14 0,000 0,05745729 0,08565195 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05745729 0,08559892 ! male genitalia development GO:0030539 24 14 0,000 0,05745729 0,08554595 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05745729 0,08549304 ! phospholipid biosynthetic process GO:0008654 167 92 1,000 0,05776195 0,08589323 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,05887297 0,08749128 ! regulation of membrane potential GO:0042391 164 93 1,000 0,05887297 0,08743727 ! female pregnancy GO:0007565 164 94 1,000 0,0599914 0,08904337 ! forebrain development GO:0030900 188 95 1,000 0,06111714 0,09065835 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06143374 0,09107183 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06143374 0,09101575 ! superoxide anion generation GO:0042554 20 15 0,000 0,06143374 0,09095974 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06143374 0,0909038 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06143374 0,09084793 ! copper ion transport GO:0006825 20 15 0,000 0,06143374 0,09079212 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06143374 0,09073639 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06143374 0,09068072 ! sulfate transport GO:0008272 23 15 0,000 0,06143374 0,09062512 ! response to cAMP GO:0051591 22 15 0,000 0,06143374 0,09056959 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06143374 0,09051413 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06143374 0,09045874 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06143374 0,09040341 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06143374 0,09034815 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06143374 0,09029296 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06143374 0,09023784 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06143374 0,09018278 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06143374 0,09012779 ! pituitary gland development GO:0021983 29 15 0,000 0,06143374 0,09007287 ! vesicle coating GO:0006901 33 15 0,000 0,06143374 0,09001801 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06143374 0,08996322 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06143374 0,0899085 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06143374 0,08985385 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06143374 0,08979926 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06143374 0,08974473 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06143374 0,08969028 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06143374 0,08963589 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06143374 0,08958156 ! histone deacetylation GO:0016575 20 15 0,000 0,06143374 0,0895273 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06143374 0,08947311 ! tissue regeneration GO:0042246 26 15 0,000 0,06143374 0,08941898 ! water homeostasis GO:0030104 27 15 0,000 0,06143374 0,08936492 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06143374 0,08931092 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06143374 0,08925699 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06143374 0,08920312 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06143374 0,08914932 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06143374 0,08909559 ! cell killing GO:0001906 29 15 0,000 0,06143374 0,08904191 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06143374 0,08898831 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06143374 0,08893476 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06143374 0,08888129 ! peptide hormone processing GO:0016486 23 15 0,000 0,06143374 0,08882787 ! mRNA transport GO:0051028 169 96 1,000 0,06225013 0,08995424 ! positive regulation of immune response GO:0050778 156 96 1,000 0,06225013 0,08990025 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,06339027 0,0914919 ! protein ubiquitination GO:0016567 217 97 1,000 0,06339027 0,09143705 ! response to virus GO:0009615 160 98 1,000 0,06453749 0,09303608 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,06453749 0,09298037 GO:0016054|organic acid catabolic process, ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06539354 0,09415731 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06539354 0,09410099 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06539354 0,09404474 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06539354 0,09398856 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06539354 0,09393245 ! bone remodeling GO:0046849 27 16 0,000 0,06539354 0,09387641 ! filopodium assembly GO:0046847 32 16 0,000 0,06539354 0,09382043 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06539354 0,09376452 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06539354 0,09370867 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06539354 0,09365289 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06539354 0,09359718 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06539354 0,09354153 ! startle response GO:0001964 28 16 0,000 0,06539354 0,09348595 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06539354 0,09343044 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06539354 0,09337499 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06539354 0,09331961 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06539354 0,09326429 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06539354 0,09320904 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06539354 0,09315385 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06539354 0,09309873 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06539354 0,09304368 ! response to osmotic stress GO:0006970 25 16 0,000 0,06539354 0,09298869 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06539354 0,09293376 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06539354 0,0928789 ! fructose metabolic process GO:0006000 25 16 0,000 0,06539354 0,0928241 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06539354 0,09276937 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06539354 0,09271471 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06539354 0,0926601 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06539354 0,09260557 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06539354 0,09255109 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06539354 0,09249668 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06539354 0,09244234 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06539354 0,09238805 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06539354 0,09233384 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06539354 0,09227968 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06539354 0,09222559 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06539354 0,09217156 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06539354 0,0921176 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06539354 0,0920637 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06539354 0,09200986 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06539354 0,09195608 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06539354 0,09190237 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06539354 0,09184872 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06933677 0,09733037 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06933677 0,09727362 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06933677 0,09721693 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06933677 0,09716031 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06933677 0,09710376 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06933677 0,09704727 ! signal complex assembly GO:0007172 41 17 0,000 0,06933677 0,09699085 ! endothelial cell migration GO:0043542 28 17 0,000 0,06933677 0,09693449 ! inositol metabolic process GO:0006020 28 17 0,000 0,06933677 0,0968782 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06933677 0,09682197 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06933677 0,09676581 ! glial cell development GO:0021782 27 17 0,000 0,06933677 0,09670971 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06933677 0,09665368 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06933677 0,09659772 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06933677 0,09654182 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06933677 0,09648598 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,06933677 0,09643021 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06933677 0,0963745 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06933677 0,09631886 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,06933677 0,09626328 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06933677 0,09620776 ! NAD metabolic process GO:0019674 29 17 0,000 0,06933677 0,09615231 ! membrane budding GO:0006900 37 17 0,000 0,06933677 0,09609692 ! DNA integration GO:0015074 29 17 0,000 0,06933677 0,0960416 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06933677 0,09598634 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06933677 0,09593114 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06933677 0,09587601 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06933677 0,09582094 ! genitalia development GO:0048806 30 17 0,000 0,06933677 0,09576593 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,06933677 0,09571099 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06933677 0,09565611 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06933677 0,09560129 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06933677 0,09554654 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06933677 0,09549185 ! steroid catabolic process GO:0006706 31 17 0,000 0,06933677 0,09543722 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06933677 0,09538265 ! gas transport GO:0015669 25 17 0,000 0,06933677 0,09532815 ! organic cation transport GO:0015695 31 17 0,000 0,06933677 0,0952737 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06933677 0,09521932 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06933677 0,09516501 ! microspike assembly GO:0030035 36 17 0,000 0,06933677 0,09511075 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06933677 0,09505656 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06933677 0,09500242 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07326348 0,10032552 ! neuron maturation GO:0042551 42 18 0,000 0,07326348 0,10026845 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07326348 0,10021145 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07326348 0,10015451 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07326348 0,10009764 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07326348 0,10004083 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07326348 0,09998409 ! memory GO:0007613 31 18 0,000 0,07326348 0,0999274 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07326348 0,09987079 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07326348 0,09981424 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07326348 0,09975775 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07326348 0,09970132 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07326348 0,09964496 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07326348 0,09958867 ! response to retinoic acid GO:0032526 26 18 0,000 0,07326348 0,09953243 ! response to fungus GO:0009620 21 18 0,000 0,07326348 0,09947627 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07326348 0,09942016 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07326348 0,09936412 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07326348 0,09930814 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07326348 0,09925222 ! vitamin transport GO:0051180 27 18 0,000 0,07326348 0,09919637 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07326348 0,09914057 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07326348 0,09908485 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07326348 0,09902918 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07326348 0,09897358 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07326348 0,09891804 ! nerve development GO:0021675 28 18 0,000 0,07326348 0,09886256 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07326348 0,09880714 ! protein secretion GO:0009306 39 19 0,000 0,07717376 0,10402245 ! positive regulation of translation GO:0045727 30 19 0,000 0,07717376 0,10396421 ! negative regulation of defense response GO:0031348 25 19 0,000 0,07717376 0,10390603 ! skin development GO:0043588 36 19 0,000 0,07717376 0,10384792 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07717376 0,10378987 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07717376 0,10373189 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07717376 0,10367397 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07717376 0,10361611 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07717376 0,10355833 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07717376 0,1035006 ! cerebral cortex development GO:0021987 36 19 0,000 0,07717376 0,10344294 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,07717376 0,10338534 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,07717376 0,10332781 ! heme metabolic process GO:0042168 36 19 0,000 0,07717376 0,10327034 ! actin filament bundle formation GO:0051017 42 19 0,000 0,07717376 0,10321294 ! neuromuscular junction development GO:0007528 34 19 0,000 0,07717376 0,1031556 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07717376 0,10309832 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07717376 0,10304111 ! peptide cross-linking GO:0018149 37 19 0,000 0,07717376 0,10298396 ! protein export from nucleus GO:0006611 36 19 0,000 0,07717376 0,10292687 ! heart process GO:0003015 30 19 0,000 0,07717376 0,10286985 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07717376 0,10281289 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07717376 0,10275599 ! visual learning GO:0008542 36 19 0,000 0,07717376 0,10269916 ! G1 phase GO:0051318 40 19 0,000 0,07717376 0,10264239 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07717376 0,10258568 ! cell-cell junction organization GO:0045216 35 19 0,000 0,07717376 0,10252903 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07717376 0,10247245 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07717376 0,10241593 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07717376 0,10235947 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07717376 0,10230307 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07717376 0,10224674 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07717376 0,10219047 ! cilium assembly GO:0042384 37 19 0,000 0,07717376 0,10213426 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07717376 0,10207811 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08106768 0,10716969 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08106768 0,10711083 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08106768 0,10705205 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08106768 0,10699332 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08106768 0,10693466 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08106768 0,10687607 ! response to vitamin GO:0033273 31 20 0,000 0,08106768 0,10681754 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08106768 0,10675907 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08106768 0,10670067 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08106768 0,10664233 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08106768 0,10658406 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08106768 0,10652585 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08106768 0,1064677 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08106768 0,10640962 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,08106768 0,1063516 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08106768 0,10629364 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08106768 0,10623574 ! body fluid secretion GO:0007589 31 20 0,000 0,08106768 0,10617791 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08106768 0,10612015 ! peptide secretion GO:0002790 35 20 0,000 0,08106768 0,10606244 ! stem cell differentiation GO:0048863 53 20 0,000 0,08106768 0,1060048 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08106768 0,10594722 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08106768 0,1058897 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08106768 0,10583224 ! sensory perception of pain GO:0019233 30 20 0,000 0,08106768 0,10577485 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08106768 0,10571752 ! diencephalon development GO:0021536 34 20 0,000 0,08106768 0,10566025 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08106768 0,10560305 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08106768 0,1055459 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08106768 0,10548882 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08106768 0,1054318 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08106768 0,10537484 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08106768 0,10531794 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08106768 0,1052611 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08106768 0,10520433 ! regulation of glucose import GO:0046324 29 20 0,000 0,08106768 0,10514762 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08106768 0,10509096 ! actin filament-based movement GO:0030048 43 20 0,000 0,08106768 0,10503437 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08106768 0,10497784 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,08106768 0,10492137 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08106768 0,10486496 ! negative regulation of translation GO:0017148 29 20 0,000 0,08106768 0,10480861 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08106768 0,10475232 ! regulation of cell killing GO:0031341 42 21 0,000 0,08494528 0,10970389 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08494528 0,10964504 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08494528 0,10958625 ! hormone secretion GO:0046879 38 21 0,000 0,08494528 0,10952752 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08494528 0,10946886 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08494528 0,10941025 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08494528 0,10935171 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08494528 0,10929324 ! axis specification GO:0009798 38 21 0,000 0,08494528 0,10923482 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08494528 0,10917647 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08494528 0,10911818 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,08494528 0,10905995 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08494528 0,10900179 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08494528 0,10894369 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08494528 0,10888564 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,08494528 0,10882767 ! cytolysis GO:0019835 24 21 0,000 0,08494528 0,10876975 ! vasodilation GO:0042311 39 21 0,000 0,08494528 0,10871189 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08494528 0,1086541 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08494528 0,10859636 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08494528 0,10853869 ! collagen fibril organization GO:0030199 59 21 0,000 0,08494528 0,10848108 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08494528 0,10842353 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,08494528 0,10836604 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08494528 0,10830861 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08494528 0,10825125 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08494528 0,10819394 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08494528 0,1081367 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08494528 0,10807951 ! collagen catabolic process GO:0030574 28 21 0,000 0,08494528 0,10802239 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08494528 0,10796532 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08880666 0,11281353 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,08880666 0,112754 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08880666 0,11269453 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08880666 0,11263512 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08880666 0,11257578 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08880666 0,11251649 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08880666 0,11245728 ! keratinization GO:0031424 28 22 0,000 0,08880666 0,11239812 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,08880666 0,11233902 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08880666 0,11227999 ! sensory perception of taste GO:0050909 28 22 0,000 0,08880666 0,11222102 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,08880666 0,11216211 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08880666 0,11210327 ! vacuolar transport GO:0007034 36 22 0,000 0,08880666 0,11204448 ! lysosome organization GO:0007040 41 22 0,000 0,08880666 0,11198576 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08880666 0,11192709 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08880666 0,11186849 ! fucose metabolic process GO:0006004 39 22 0,000 0,08880666 0,11180995 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08880666 0,11175148 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,08880666 0,11169306 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08880666 0,1116347 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08880666 0,11157641 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08880666 0,11151818 ! sarcomere organization GO:0045214 30 22 0,000 0,08880666 0,11146 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,08880666 0,11140189 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08880666 0,11134384 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08880666 0,11128585 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08880666 0,11122791 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08880666 0,11117004 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08880666 0,11111223 ! protein stabilization GO:0050821 39 22 0,000 0,08880666 0,11105448 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09265187 0,1158028 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09265187 0,11574268 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,09265187 0,11568261 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09265187 0,11562261 ! gluconeogenesis GO:0006094 33 23 0,000 0,09265187 0,11556267 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09265187 0,1155028 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09265187 0,11544298 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09265187 0,11538323 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09265187 0,11532354 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09265187 0,11526391 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09265187 0,11520434 ! visual behavior GO:0007632 42 23 0,000 0,09265187 0,11514483 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,09265187 0,11508539 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09265187 0,115026 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09265187 0,11496668 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09265187 0,11490742 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09265187 0,11484822 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09265187 0,11478908 ! sex determination GO:0007530 47 23 0,000 0,09265187 0,11473 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09265187 0,11467099 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09265187 0,11461203 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09265187 0,11455313 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09265187 0,1144943 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09265187 0,11443552 ! platelet activation GO:0030168 37 23 0,000 0,09265187 0,11437681 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09265187 0,11431815 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09265187 0,11425956 ! hormone transport GO:0009914 40 23 0,000 0,09265187 0,11420102 ! cell-cell recognition GO:0009988 25 23 0,000 0,09265187 0,11414255 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09265187 0,11408413 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09265187 0,11402578 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,09265187 0,11396748 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09265187 0,11390925 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09265187 0,11385107 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,09648098 0,11849578 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09648098 0,11843532 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,09648098 0,11837493 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09648098 0,11831459 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09648098 0,11825432 ! vesicle docking GO:0048278 47 24 0,000 0,09648098 0,11819411 ! spinal cord development GO:0021510 47 24 0,000 0,09648098 0,11813396 ! vacuole organization GO:0007033 43 24 0,000 0,09648098 0,11807387 ! digestive system process GO:0022600 39 24 0,000 0,09648098 0,11801384 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09648098 0,11795388 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09648098 0,11789397 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09648098 0,11783413 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,09648098 0,11777434 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09648098 0,11771462 ! membrane depolarization GO:0051899 39 24 0,000 0,09648098 0,11765496 ! pentose metabolic process GO:0019321 35 24 0,000 0,09648098 0,11759536 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09648098 0,11753581 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09648098 0,11747633 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09648098 0,11741691 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09648098 0,11735755 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09648098 0,11729825 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09648098 0,11723901 ! regulation of amine transport GO:0051952 40 24 0,000 0,09648098 0,11717982 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10029405 0,12174949 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,10029405 0,1216881 ! myelination GO:0042552 45 25 0,000 0,10029405 0,12162676 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10029405 0,12156549 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10029405 0,12150428 ! phototransduction GO:0007602 33 25 0,000 0,10029405 0,12144313 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10029405 0,12138204 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,10029405 0,12132101 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10029405 0,12126005 ! chromosome condensation GO:0030261 45 25 0,000 0,10029405 0,12119914 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10029405 0,1211383 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10029405 0,12107752 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10029405 0,1210168 ! interaction with host GO:0051701 62 25 0,000 0,10029405 0,12095614 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10029405 0,12089554 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10029405 0,120835 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10029405 0,12077452 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10029405 0,1207141 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10029405 0,12065375 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10029405 0,12059345 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10029405 0,12053321 ! telomere organization GO:0032200 43 25 0,000 0,10029405 0,12047304 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10029405 0,12041292 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10029405 0,12035287 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10409117 0,12484713 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10409117 0,12478492 ! initiation of viral infection GO:0019059 57 26 0,000 0,10409117 0,12472278 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10409117 0,1246607 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10409117 0,12459868 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10409117 0,12453672 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10409117 0,12447482 ! tube lumen formation GO:0035148 50 26 0,000 0,10409117 0,12441299 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,10409117 0,12435121 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,10409117 0,1242895 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,10409117 0,12422785 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,10409117 0,12416626 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10409117 0,12410473 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10409117 0,12404326 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10409117 0,12398185 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,10409117 0,12392051 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10409117 0,12385922 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,10409117 0,12379799 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,10409117 0,12373683 ! blastocyst development GO:0001824 49 26 0,000 0,10409117 0,12367573 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10409117 0,12361468 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,10409117 0,1235537 ! neuron fate commitment GO:0048663 48 27 0,000 0,10787238 0,12797877 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,10787238 0,12791569 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,10787238 0,12785268 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,10787238 0,12778973 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10787238 0,12772684 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,10787238 0,12766401 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10787238 0,12760125 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,10787238 0,12753854 ! autophagy GO:0006914 41 27 0,000 0,10787238 0,1274759 ! primary neural tube formation GO:0014020 51 27 0,000 0,10787238 0,12741332 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10787238 0,1273508 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10787238 0,12728835 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,10787238 0,12722595 ! glutathione metabolic process GO:0006749 39 27 0,000 0,10787238 0,12716361 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,10787238 0,12710134 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,10787238 0,12703913 ! circadian rhythm GO:0007623 50 28 0,000 0,11163775 0,13140922 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11163775 0,13134496 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11163775 0,13128076 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,11163775 0,13121663 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11163775 0,13115256 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11163775 0,13108855 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,11163775 0,1310246 ! synaptogenesis GO:0007416 42 28 0,000 0,11163775 0,13096072 ! lipid oxidation GO:0034440 43 28 0,000 0,11163775 0,1308969 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11163775 0,13083314 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,11163775 0,13076944 ! translational initiation GO:0006413 65 29 0,000 0,11538736 0,13509586 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11538736 0,13503015 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11538736 0,13496451 ! catechol metabolic process GO:0009712 54 29 0,000 0,11538736 0,13489893 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,11538736 0,13483341 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,11538736 0,13476796 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,11538736 0,13470257 ! cell fate determination GO:0001709 60 29 0,000 0,11538736 0,13463724 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11538736 0,13457198 ! detection of light stimulus GO:0009583 38 29 0,000 0,11538736 0,13450678 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,11538736 0,13444164 ! regulation of coagulation GO:0050818 46 29 0,000 0,11538736 0,13437657 ! phenol metabolic process GO:0018958 55 30 0,000 0,11912127 0,13865785 ! zinc ion transport GO:0006829 45 30 0,000 0,11912127 0,1385908 ! membrane docking GO:0022406 61 30 0,000 0,11912127 0,13852382 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,11912127 0,1384569 ! regulation of innate immune response GO:0045088 51 30 0,000 0,11912127 0,13839004 ! acute-phase response GO:0006953 49 30 0,000 0,11912127 0,13832325 ! myofibril assembly GO:0030239 47 30 0,000 0,11912127 0,13825653 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,11912127 0,13818986 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,11912127 0,13812327 ! phospholipid transport GO:0015914 51 30 0,000 0,11912127 0,13805673 ! ensheathment of neurons GO:0007272 57 30 0,000 0,11912127 0,13799026 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,11912127 0,13792386 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,11912127 0,13785752 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,11912127 0,13779124 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,11912127 0,13772503 ! eye morphogenesis GO:0048592 60 30 0,000 0,11912127 0,13765887 ! regulation of B cell activation GO:0050864 50 30 0,000 0,11912127 0,13759279 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12283954 0,14181955 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,12283954 0,14175153 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12283954 0,14168357 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12283954 0,14161569 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12283954 0,14154786 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12283954 0,1414801 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12283954 0,14141241 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,12283954 0,14134478 ! peptide transport GO:0015833 55 31 0,000 0,12283954 0,14127722 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,12283954 0,14120972 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,12283954 0,14114228 ! mesoderm formation GO:0001707 69 31 0,000 0,12283954 0,14107491 ! natural killer cell activation GO:0030101 45 31 0,000 0,12283954 0,1410076 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12283954 0,14094036 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12283954 0,14087318 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,12283954 0,14080607 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12283954 0,14073902 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,12654224 0,14491225 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,12654224 0,14484331 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,12654224 0,14477443 ! cholesterol transport GO:0030301 56 32 0,000 0,12654224 0,14470562 ! spliceosome assembly GO:0000245 67 32 0,000 0,12654224 0,14463688 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,12654224 0,1445682 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,12654224 0,14449959 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,12654224 0,14443104 ! muscle cell development GO:0055001 49 32 0,000 0,12654224 0,14436255 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,12654224 0,14429414 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,12654224 0,14422578 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,12654224 0,14415749 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,12654224 0,14408927 ! peripheral nervous system development GO:0007422 64 32 0,000 0,12654224 0,14402111 ! BMP signaling pathway GO:0030509 64 32 0,000 0,12654224 0,14395302 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,12654224 0,14388498 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,12654224 0,14381702 ! gene silencing GO:0016458 65 32 0,000 0,12654224 0,14374912 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13022943 0,14786787 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13022943 0,14779812 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13022943 0,14772843 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13022943 0,14765882 ! sterol transport GO:0015918 57 33 0,000 0,13022943 0,14758926 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13022943 0,14751978 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,13022943 0,14745036 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13022943 0,147381 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,13390118 0,15146508 ! glial cell differentiation GO:0010001 63 34 0,000 0,13390118 0,15139391 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,13390118 0,1513228 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13390118 0,15125175 ! mismatch repair GO:0006298 46 34 0,000 0,13390118 0,15118078 ! spermatid development GO:0007286 63 34 0,000 0,13390118 0,15110987 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,13390118 0,15103902 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,13390118 0,15096824 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,13390118 0,15089753 ! negative regulation of secretion GO:0051048 63 35 0,000 0,13755755 0,15494544 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,13755755 0,15487293 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,13755755 0,15480049 ! odontogenesis GO:0042476 66 35 0,000 0,13755755 0,15472812 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,13755755 0,15465582 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,13755755 0,15458359 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 0,000 0,13755755 0,15451142 ! cytokine production GO:0001816 59 35 0,000 0,13755755 0,15443932 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,13755755 0,15436728 ! vesicle localization GO:0051648 64 35 0,000 0,13755755 0,15429532 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,1411986 0,15830561 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,1411986 0,15823187 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,1411986 0,15815821 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,1411986 0,15808461 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,1411986 0,15801109 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,1411986 0,15793763 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,1411986 0,15786424 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,1411986 0,15779091 ! aerobic respiration GO:0009060 55 36 0,000 0,1411986 0,15771766 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,1411986 0,15764447 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,1411986 0,15757135 ! RNA export from nucleus GO:0006405 56 37 0,000 0,1448244 0,16154266 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,1448244 0,1614678 ! meiosis I GO:0007127 65 37 0,000 0,1448244 0,16139301 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,1448244 0,16131829 ! sister chromatid segregation GO:0000819 58 37 0,000 0,1448244 0,16124364 ! actomyosin structure organization GO:0031032 62 37 0,000 0,1448244 0,16116906 ! organic anion transport GO:0015711 68 37 0,000 0,1448244 0,16109455 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,1448244 0,16102011 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,1448244 0,16094574 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,1448244 0,16087143 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,1448244 0,16079719 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,1448244 0,16072302 ! spermatid differentiation GO:0048515 66 37 0,000 0,1448244 0,16064892 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,14843502 0,16457818 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,14843502 0,16450237 ! nucleus organization GO:0006997 67 38 0,000 0,14843502 0,16442664 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,14843502 0,16435097 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,14843502 0,16427537 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,14843502 0,16419984 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,14843502 0,16412438 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,14843502 0,16404899 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,15203051 0,16794555 ! learning GO:0007612 77 39 0,000 0,15203051 0,16786847 ! ear morphogenesis GO:0042471 60 39 0,000 0,15203051 0,16779147 ! organic ether metabolic process GO:0018904 55 39 0,000 0,15203051 0,16771454 ! ion transmembrane transport GO:0034220 66 39 0,000 0,15203051 0,16763767 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,15203051 0,16756088 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,15203051 0,16748416 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,15203051 0,16740751 ! RNA modification GO:0009451 57 39 0,000 0,15203051 0,16733093 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,15561094 0,17119338 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,15561094 0,17111514 ! negative regulation of binding GO:0051100 72 40 0,000 0,15561094 0,17103697 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,15561094 0,17095887 ! maintenance of protein location GO:0045185 91 40 0,000 0,15561094 0,17088084 ! cytokinesis GO:0000910 72 40 0,000 0,15561094 0,17080288 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,15917637 0,17463673 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,15917637 0,17455713 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,15917637 0,1744776 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,15917637 0,17439815 ! gliogenesis GO:0042063 88 41 0,000 0,15917637 0,17431877 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,15917637 0,17423946 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,15917637 0,17416023 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,15917637 0,17408106 ! polyol metabolic process GO:0019751 66 41 0,000 0,15917637 0,17400197 ! regulation of tube size GO:0035150 71 42 0,000 0,16272686 0,17780237 GO:0050880|regulation of blood vessel size, ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,16272686 0,17772166 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,16272686 0,17764103 ! neuron migration GO:0001764 79 42 0,000 0,16272686 0,17756046 ! regulation of protein secretion GO:0050708 71 42 0,000 0,16272686 0,17747997 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,16626248 0,18125397 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,16626248 0,18117188 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,16626248 0,18108987 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,16626248 0,18100793 ! glucose transport GO:0015758 65 43 0,000 0,16626248 0,18092606 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,16626248 0,18084427 ! striated muscle contraction GO:0006941 77 43 0,000 0,16626248 0,18076255 ! phagocytosis GO:0006909 90 43 0,000 0,16626248 0,1806809 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,16626248 0,18059933 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,16978328 0,18434051 ! hexose transport GO:0008645 67 44 0,000 0,16978328 0,18425736 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,16978328 0,18417429 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,16978328 0,18409129 ! maintenance of location in cell GO:0051651 97 44 0,000 0,16978328 0,18400837 ! glycolysis GO:0006096 65 45 0,000 0,17328933 0,18772361 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,17328933 0,18763913 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,17328933 0,18755472 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,17328933 0,18747038 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,17328933 0,18738613 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,17328933 0,18730195 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,17328933 0,18721784 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,17328933 0,18713381 ! cell growth GO:0016049 84 45 0,000 0,17328933 0,18704986 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,1767807 0,19073289 ! positive regulation of defense response GO:0031349 76 47 0,000 0,18025743 0,19439685 ! response to calcium ion GO:0051592 81 47 0,000 0,18025743 0,19430976 ! endosome transport GO:0016197 108 47 0,000 0,18025743 0,19422274 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,18025743 0,1941358 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,18025743 0,19404894 ! JNK cascade GO:0007254 91 47 0,000 0,18025743 0,19396215 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,18025743 0,19387545 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,18371959 0,19751088 ! Notch signaling pathway GO:0007219 96 48 0,000 0,18371959 0,19742266 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,18371959 0,19733453 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,18371959 0,19724647 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,18371959 0,19715849 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,18371959 0,19707059 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,18371959 0,19698277 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,18371959 0,19689503 ! regulation of action potential GO:0001508 95 49 0,000 0,18716725 0,20050063 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,18716725 0,2004114 ! regulation of ion transport GO:0043269 77 49 0,000 0,18716725 0,20032225 ! peptide metabolic process GO:0006518 76 49 0,000 0,18716725 0,20023317 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,18716725 0,20014418 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,18716725 0,20005527 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,18716725 0,19996643 ! inner ear development GO:0048839 79 50 0,000 0,19060046 0,20354404 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,19060046 0,20345373 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,19401928 0,20701126 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,19401928 0,2069195 ! excretion GO:0007588 83 51 0,000 0,19401928 0,20682782 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,19401928 0,20673623 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,19401928 0,20664471 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,19401928 0,20655327 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 0,000 0,19742378 0,21008475 ! membrane fusion GO:0006944 110 52 0,000 0,19742378 0,20999187 ! synapse organization GO:0050808 85 52 0,000 0,19742378 0,20989908 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,20081401 0,21340923 ! RNA catabolic process GO:0006401 93 53 0,000 0,20081401 0,21331501 ! regulation of translational initiation GO:0006446 82 53 0,000 0,20081401 0,21322087 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,20081401 0,21312682 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,20419003 0,21661429 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,20419003 0,21651882 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,20419003 0,21642344 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,20419003 0,21632814 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,20419003 0,21623292 ! chloride transport GO:0006821 90 55 0,000 0,20755189 0,21969637 ! glucose catabolic process GO:0006007 82 55 0,000 0,20755189 0,21959976 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,20755189 0,21950323 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,20755189 0,21940679 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,20755189 0,21931043 ! gastrulation GO:0007369 112 55 0,000 0,20755189 0,21921416 ! RNA elongation GO:0006354 79 55 0,000 0,20755189 0,21911797 ! nuclear export GO:0051168 97 55 0,000 0,20755189 0,21902187 ! sensory perception of smell GO:0007608 80 56 0,000 0,21089967 0,22245709 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,21089967 0,2223596 ! proton transport GO:0015992 94 56 0,000 0,21089967 0,2222622 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,21089967 0,22216489 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,21423342 0,22557795 ! maintenance of location GO:0051235 118 57 0,000 0,21423342 0,22547927 ! hydrogen transport GO:0006818 97 58 0,000 0,21755319 0,22887319 ! regulation of endocytosis GO:0030100 91 58 0,000 0,21755319 0,22877315 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,21755319 0,22867321 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,22085905 0,23204667 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,22085905 0,23194538 ! establishment of organelle localization GO:0051656 109 59 0,000 0,22085905 0,23184418 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,22415105 0,2351973 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,22415105 0,23509478 ! regulation of heart contraction GO:0008016 110 60 0,000 0,22415105 0,23499234 ! camera-type eye development GO:0043010 116 60 0,000 0,22415105 0,23488999 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,22415105 0,23478773 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,22415105 0,23468556 ! mesoderm development GO:0007498 119 61 0,000 0,22742925 0,23801425 ! tRNA processing GO:0008033 89 61 0,000 0,22742925 0,23791077 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,22742925 0,23780737 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,2306937 0,24111601 ! regulation of mitosis GO:0007088 105 63 0,000 0,23394447 0,24440747 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,23394447 0,24430139 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,23394447 0,2441954 ! cell redox homeostasis GO:0045454 102 64 0,000 0,23718161 0,24746703 ! single fertilization GO:0007338 75 64 0,000 0,23718161 0,24735976 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,24040518 0,25061303 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,24040518 0,25050449 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,24361524 0,25373951 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,24361524 0,25362971 ! extracellular matrix organization GO:0030198 133 66 0,000 0,24361524 0,25352001 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,24681183 0,25673552 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,24681183 0,25662457 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,24681183 0,25651372 ! activation of MAPK activity GO:0000187 115 67 0,000 0,24681183 0,25640296 ! chromosome segregation GO:0007059 113 67 0,000 0,24681183 0,2562923 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,24681183 0,25618174 ! hexose catabolic process GO:0019320 104 67 0,000 0,24681183 0,25607127 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,24681183 0,25596089 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,24681183 0,25585061 ! amino acid transport GO:0006865 125 68 0,000 0,24999502 0,25903877 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,24999502 0,25892726 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,24999502 0,25881584 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,24999502 0,25870453 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,24999502 0,2585933 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,24999502 0,25848218 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,25316487 0,26164719 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,25316487 0,26153485 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,25316487 0,2614226 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,25946473 0,26781302 ! regulation of immune effector process GO:0002697 137 71 0,000 0,25946473 0,26769818 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,26259487 0,27081151 ! carbohydrate transport GO:0008643 110 72 0,000 0,26259487 0,27069548 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,26259487 0,27057955 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,26259487 0,27046372 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,26259487 0,27034799 ! learning or memory GO:0007611 147 73 0,000 0,26571187 0,27344002 ! fertilization GO:0009566 90 73 0,000 0,26571187 0,27332311 ! neurotransmitter transport GO:0006836 123 74 0,000 0,26881581 0,27639779 ! meiosis GO:0007126 121 74 0,000 0,26881581 0,27627972 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,26881581 0,27616175 ! eye development GO:0001654 143 74 0,000 0,26881581 0,27604389 ! organelle localization GO:0051640 136 74 0,000 0,26881581 0,27592612 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,27190672 0,27897977 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,27190672 0,27886086 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,27190672 0,27874204 ! meiotic cell cycle GO:0051321 122 75 0,000 0,27190672 0,27862333 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,27498467 0,28165735 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,27498467 0,2815375 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,27804972 0,2845545 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,27804972 0,28443351 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,27804972 0,28431263 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,2811019 0,28731146 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,28414129 0,29029467 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,28414129 0,29017145 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,28414129 0,29004834 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,28414129 0,28992533 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,28716792 0,29288937 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,28716792 0,29276526 ! inorganic anion transport GO:0015698 138 80 0,000 0,28716792 0,29264126 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,29018186 0,29558745 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,29018186 0,29546236 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,29318316 0,29839199 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,29318316 0,29826582 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,29318316 0,29813976 ! regulation of lyase activity GO:0051339 160 83 0,000 0,29617186 0,30105175 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,29914803 0,30394854 ! negative regulation of transport GO:0051051 153 84 0,000 0,29914803 0,30382024 ! regulation of ligase activity GO:0051340 142 84 0,000 0,29914803 0,30369205 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,29914803 0,30356396 ! response to unfolded protein GO:0006986 131 85 0,000 0,30211171 0,30644214 ! nucleosome assembly GO:0006334 122 85 0,000 0,30211171 0,30631301 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,30211171 0,30618398 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,30506295 0,30904483 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,30506295 0,30891476 ! chromatin assembly GO:0031497 124 86 0,000 0,30506295 0,3087848 ! alcohol catabolic process GO:0046164 130 86 0,000 0,30506295 0,30865495 ! amine transport GO:0015837 155 86 0,000 0,30506295 0,30852521 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,30800182 0,31136654 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,31092835 0,31419303 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,31092835 0,31406113 ! regulation of neurological system process GO:0031644 148 88 0,000 0,31092835 0,31392934 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,31092835 0,31379765 ! cellular defense response GO:0006968 114 89 0,000 0,3138426 0,316606 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,31674463 0,31939965 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,31674463 0,31926584 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,31674463 0,31913215 ! sterol metabolic process GO:0016125 152 91 0,000 0,31963447 0,32190897 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,31963447 0,32177428 ! regulation of defense response GO:0031347 149 92 0,000 0,32251219 0,32453548 ! nucleosome organization GO:0034728 138 92 0,000 0,32251219 0,32439981 ! vitamin metabolic process GO:0006766 139 92 0,000 0,32251219 0,32426424 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,32537784 0,3270088 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,32537784 0,32687226 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,32537784 0,32673584 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,32823145 0,32946386 ! transcription initiation GO:0006352 153 94 0,000 0,32823145 0,32932647 ! regulation of T cell activation GO:0050863 158 94 0,000 0,32823145 0,32918919 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,3310731 0,33190078 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,33390281 0,33459815 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,33672065 0,33728138 ! hormone metabolic process GO:0042445 157 97 0,000 0,33672065 0,33714103 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,33952666 0,33980913 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,3423209 0,34246323 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,3423209 0,3423209