pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1211-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 4,451E-10 1,087E-06 ! fat cell differentiation GO:0045444 57 28 4,000 8,962E-08 1,095E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 4,000 1,079E-07 8,79E-05 ! regulation of hormone metabolic process GO:0032350 28 12 3,000 1,213E-07 7,406E-05 ! epithelial to mesenchymal transition GO:0001837 30 15 3,000 3,312E-07 1,618E-04 ! androgen receptor signaling pathway GO:0030521 81 37 4,000 3,861E-07 1,572E-04 ! carbohydrate homeostasis GO:0033500 59 39 4,000 5,067E-07 1,768E-04 GO:0042593|glucose homeostasis, ! regulation of mitochondrial membrane permeability GO:0046902 15 5 2,000 6,339E-07 1,936E-04 ! mesenchymal cell development GO:0014031 94 41 4,000 6,552E-07 1,779E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pancreas development GO:0031016 40 20 3,000 1,157E-06 2,828E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 1,264E-06 2,807E-04 ! negative regulation of growth GO:0045926 168 85 5,000 1,285E-06 2,616E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 2,206E-06 4,145E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 2,206E-06 3,849E-04 ! negative regulation of cell development GO:0010721 83 26 3,000 3,505E-06 5,709E-04 GO:0050768|negative regulation of neurogenesis, ! positive regulation of insulin secretion GO:0032024 17 8 2,000 3,518E-06 5,372E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 3,518E-06 5,056E-04 ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 7,207E-06 9,782E-04 ! protein sumoylation GO:0016925 17 10 2,000 7,495E-06 9,637E-04 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 7,495E-06 9,155E-04 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 2,000 1,028E-05 1,195E-03 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 1,028E-05 1,141E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 1,033E-05 1,097E-03 ! response to hypoxia GO:0001666 178 81 4,000 1,969E-05 2,004E-03 ! response to oxygen levels GO:0070482 183 83 4,000 2,217E-05 2,166E-03 ! response to gamma radiation GO:0010332 30 14 2,000 2,247E-05 2,111E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 2,247E-05 2,033E-03 ! negative regulation of bone remodeling GO:0046851 34 15 2,000 2,8E-05 2,443E-03 ! negative regulation of tissue remodeling GO:0034104 37 16 2,000 3,436E-05 2,895E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 3,594E-05 2,927E-03 ! pigmentation GO:0043473 103 46 3,000 3,594E-05 2,833E-03 ! myoblast differentiation GO:0045445 50 17 2,000 4,16E-05 3,176E-03 ! negative regulation of homeostatic process GO:0032845 36 17 2,000 4,16E-05 3,08E-03 ! detection of bacterium GO:0016045 22 18 2,000 4,978E-05 3,577E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 5,893E-05 4,114E-03 ! cellular pigmentation GO:0033059 37 19 2,000 5,893E-05 3,999E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 6,913E-05 4,565E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 9,002E-05 5,787E-03 ! cell aging GO:0007569 48 22 2,000 9,284E-05 5,815E-03 ! regulation of homeostatic process GO:0032844 148 62 3,000 1,169E-04 7,139E-03 ! detection of biotic stimulus GO:0009595 34 24 2,000 1,213E-04 7,228E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 1,323E-04 7,696E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 1,374E-04 7,808E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 1,374E-04 7,631E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 1,406E-04 7,631E-03 ! negative regulation of cell growth GO:0030308 142 67 3,000 1,581E-04 8,398E-03 ! positive regulation of muscle development GO:0048636 15 5 1,000 1,595E-04 8,289E-03 GO:0045844|positive regulation of striated muscle development, ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 1,595E-04 8,116E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,595E-04 7,95E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,595E-04 7,791E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,595E-04 7,638E-03 ! microvillus organization GO:0032528 8 5 1,000 1,595E-04 7,492E-03 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 10 5 1,000 1,595E-04 7,35E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 1,595E-04 7,214E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 1,595E-04 7,083E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 1,595E-04 6,956E-03 ! B cell homeostasis GO:0001782 13 5 1,000 1,595E-04 6,834E-03 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 1,595E-04 6,717E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,595E-04 6,603E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,595E-04 6,493E-03 ! receptor biosynthetic process GO:0032800 7 5 1,000 1,595E-04 6,386E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 1,738E-04 6,846E-03 ! mitochondrial membrane organization GO:0007006 60 27 2,000 1,738E-04 6,738E-03 ! response to toxin GO:0009636 49 27 2,000 1,738E-04 6,632E-03 ! cellular response to oxidative stress GO:0034599 43 27 2,000 1,738E-04 6,53E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 1,773E-04 6,561E-03 ! lung development GO:0030324 165 69 3,000 1,773E-04 6,463E-03 ! respiratory tube development GO:0030323 171 72 3,000 2,09E-04 7,508E-03 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 2,158E-04 7,64E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 2,158E-04 7,531E-03 ! humoral immune response GO:0006959 115 73 3,000 2,204E-04 7,584E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 2,323E-04 7,881E-03 ! respiratory system development GO:0060541 175 74 3,000 2,323E-04 7,773E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 2,386E-04 7,876E-03 ! embryonic hemopoiesis GO:0035162 16 6 1,000 2,386E-04 7,771E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,386E-04 7,668E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,386E-04 7,569E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 1,000 2,386E-04 7,472E-03 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 2,386E-04 7,377E-03 ! negative regulation of multicellular organism growth GO:0040015 9 6 1,000 2,386E-04 7,285E-03 ! oxygen homeostasis GO:0032364 10 6 1,000 2,386E-04 7,195E-03 ! protein deubiquitination GO:0016579 16 6 1,000 2,386E-04 7,107E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,386E-04 7,022E-03 ! negative regulation of axon extension GO:0030517 24 6 1,000 2,386E-04 6,938E-03 ! iron ion homeostasis GO:0055072 60 31 2,000 2,639E-04 7,584E-03 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 2,706E-04 7,688E-03 ! steroid biosynthetic process GO:0006694 146 79 3,000 2,986E-04 8,386E-03 ! positive regulation of gene-specific transcription GO:0043193 70 33 2,000 3,184E-04 8,84E-03 ! response to ionizing radiation GO:0010212 74 33 2,000 3,184E-04 8,741E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 3,331E-04 9,042E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 3,331E-04 8,942E-03 ! mRNA stabilization GO:0048255 18 7 1,000 3,331E-04 8,845E-03 GO:0043489|RNA stabilization, ! lipoprotein transport GO:0042953 14 7 1,000 3,331E-04 8,75E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 1,000 3,331E-04 8,657E-03 ! organ growth GO:0035265 15 7 1,000 3,331E-04 8,566E-03 ! attachment of GPI anchor to protein GO:0016255 16 7 1,000 3,331E-04 8,477E-03 ! monocyte differentiation GO:0030224 16 7 1,000 3,331E-04 8,389E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 3,331E-04 8,304E-03 ! eating behavior GO:0042755 8 7 1,000 3,331E-04 8,22E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 3,331E-04 8,138E-03 ! axonal fasciculation GO:0007413 19 7 1,000 3,331E-04 8,057E-03 ! peptidyl-threonine modification GO:0018210 26 7 1,000 3,331E-04 7,978E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 3,331E-04 7,901E-03 ! protein modification by small protein removal GO:0070646 19 7 1,000 3,331E-04 7,825E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 3,444E-04 8,013E-03 ! protein import into nucleus GO:0006606 174 82 3,000 3,444E-04 7,938E-03 ! response to drug GO:0042493 149 83 3,000 3,607E-04 8,236E-03 ! nuclear import GO:0051170 177 83 3,000 3,607E-04 8,16E-03 ! placenta development GO:0001890 53 35 2,000 3,797E-04 8,511E-03 ! regulation of neuron differentiation GO:0045664 187 85 3,000 3,95E-04 8,773E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 4,43E-04 9,749E-03 ! hemoglobin metabolic process GO:0020027 14 8 1,000 4,43E-04 9,662E-03 ! pigment granule organization GO:0048753 17 8 1,000 4,43E-04 9,577E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,43E-04 9,493E-03 ! ER overload response GO:0006983 13 8 1,000 4,43E-04 9,41E-03 ! regulation of pigmentation during development GO:0048070 25 8 1,000 4,43E-04 9,329E-03 ! melanin metabolic process GO:0006582 17 8 1,000 4,43E-04 9,249E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 4,43E-04 9,171E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 4,43E-04 9,094E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 4,43E-04 9,018E-03 ! response to UV-B GO:0010224 17 8 1,000 4,43E-04 8,943E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 4,43E-04 8,87E-03 ! gas homeostasis GO:0033483 14 8 1,000 4,43E-04 8,798E-03 ! response to tumor cell GO:0002347 16 8 1,000 4,43E-04 8,727E-03 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 4,43E-04 8,657E-03 ! tissue remodeling GO:0048771 78 37 2,000 4,482E-04 8,689E-03 ! tube morphogenesis GO:0035239 194 89 3,000 4,704E-04 9,05E-03 ! protein localization in nucleus GO:0034504 192 89 3,000 4,704E-04 8,979E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 4,852E-04 9,188E-03 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 5,556E-04 0,01044155 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,68E-04 0,01059291 ! induction of positive chemotaxis GO:0050930 17 9 1,000 5,68E-04 0,01051266 ! regulation of glycolysis GO:0006110 20 9 1,000 5,68E-04 0,01043362 ! T cell selection GO:0045058 27 9 1,000 5,68E-04 0,01035576 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 5,68E-04 0,01027905 ! glycine catabolic process GO:0006546 15 9 1,000 5,68E-04 0,01020347 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 5,68E-04 0,01012899 ! negative regulation of multicellular organismal process GO:0051241 174 95 3,000 6,021E-04 0,01065865 ! regulation of hormone secretion GO:0046883 69 41 2,000 6,077E-04 0,01068019 ! T cell differentiation GO:0030217 93 42 2,000 6,525E-04 0,01138608 ! leukocyte differentiation GO:0002521 232 98 3,000 6,768E-04 0,01172713 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 6,768E-04 0,01164455 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 7,082E-04 0,01209798 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 7,082E-04 0,01201397 ! lung alveolus development GO:0048286 26 10 1,000 7,082E-04 0,01193111 ! B cell proliferation GO:0042100 19 10 1,000 7,082E-04 0,01184939 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 7,082E-04 0,01176879 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 7,082E-04 0,01168927 ! regulation of bone resorption GO:0045124 25 10 1,000 7,082E-04 0,01161082 ! regulation of gliogenesis GO:0014013 23 10 1,000 7,082E-04 0,01153341 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 7,082E-04 0,01145703 ! regulation of fat cell differentiation GO:0045598 18 10 1,000 7,082E-04 0,01138165 ! induction of an organ GO:0001759 17 10 1,000 7,082E-04 0,01130726 ! serine family amino acid catabolic process GO:0009071 18 10 1,000 7,082E-04 0,01123384 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 7,082E-04 0,01116136 GO:0043470|regulation of carbohydrate catabolic process, ! response to nicotine GO:0035094 20 10 1,000 7,082E-04 0,01108982 ! skeletal muscle tissue development GO:0007519 223 100 3,000 7,302E-04 0,0113621 GO:0060538|skeletal muscle organ development, ! response to reactive oxygen species GO:0000302 75 44 2,000 7,483E-04 0,01157099 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 7,995E-04 0,01228339 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 7,995E-04 0,01220662 ! B cell differentiation GO:0030183 124 45 2,000 7,995E-04 0,0121308 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 8,527E-04 0,01285921 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 8,632E-04 0,01293792 ! keratinocyte proliferation GO:0043616 19 11 1,000 8,632E-04 0,01285903 ! blood vessel remodeling GO:0001974 30 11 1,000 8,632E-04 0,01278109 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 8,632E-04 0,0127041 ! regulation of intracellular pH GO:0051453 21 11 1,000 8,632E-04 0,01262803 ! behavioral fear response GO:0001662 27 11 1,000 8,632E-04 0,01255286 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 1,000 8,632E-04 0,01247858 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 8,632E-04 0,01240518 ! regulation of smoothened signaling pathway GO:0008589 27 11 1,000 8,632E-04 0,01233263 ! alpha-beta T cell activation GO:0046631 26 11 1,000 8,632E-04 0,01226093 ! negative regulation of axonogenesis GO:0050771 37 11 1,000 8,632E-04 0,01219006 ! nitric oxide metabolic process GO:0046209 17 11 1,000 8,632E-04 0,01212 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 1,000 8,632E-04 0,01205074 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 25 11 1,000 8,632E-04 0,01198227 ! apical protein localization GO:0045176 18 11 1,000 8,632E-04 0,01191458 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 8,632E-04 0,01184764 ! thymus development GO:0048538 29 11 1,000 8,632E-04 0,01178145 ! oocyte development GO:0048599 20 11 1,000 8,632E-04 0,011716 ! regulation of embryonic development GO:0045995 35 11 1,000 8,632E-04 0,01165127 ! response to insulin stimulus GO:0032868 98 47 2,000 9,082E-04 0,01219069 ! mitochondrial transport GO:0006839 94 48 2,000 9,659E-04 0,01289444 ! JAK-STAT cascade GO:0007259 82 48 2,000 9,659E-04 0,01282436 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,033E-03 0,01364315 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 1,033E-03 0,0135698 GO:0050927|positive regulation of positive chemotaxis, ! protein complex disassembly GO:0043241 28 12 1,000 1,033E-03 0,01349723 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 29 12 1,000 1,033E-03 0,01342544 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,033E-03 0,0133544 ! focal adhesion formation GO:0048041 37 12 1,000 1,033E-03 0,01328412 ! mitotic spindle organization GO:0007052 23 12 1,000 1,033E-03 0,01321457 ! histone acetylation GO:0016573 27 12 1,000 1,033E-03 0,01314574 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,033E-03 0,01307763 ! T cell homeostasis GO:0043029 28 12 1,000 1,033E-03 0,01301022 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,033E-03 0,0129435 ! oocyte differentiation GO:0009994 21 12 1,000 1,033E-03 0,01287746 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,033E-03 0,01281209 ! developmental induction GO:0031128 22 12 1,000 1,033E-03 0,01274738 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 1,000 1,033E-03 0,01268333 ! activation of caspase activity GO:0006919 95 50 2,000 1,088E-03 0,01329183 ! negative regulation of cell projection organization GO:0031345 42 13 1,000 1,218E-03 0,01480111 ! regulation of chemokine production GO:0032642 18 13 1,000 1,218E-03 0,01472784 ! cartilage condensation GO:0001502 22 13 1,000 1,218E-03 0,01465529 ! endocrine pancreas development GO:0031018 25 13 1,000 1,218E-03 0,01458345 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,218E-03 0,01451231 ! response to X-ray GO:0010165 28 13 1,000 1,218E-03 0,01444186 ! asymmetric protein localization GO:0008105 24 13 1,000 1,218E-03 0,01437209 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,218E-03 0,014303 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 1,218E-03 0,01423456 ! ribosomal large subunit biogenesis GO:0042273 13 13 1,000 1,218E-03 0,01416678 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,218E-03 0,01409964 ! gland morphogenesis GO:0022612 31 13 1,000 1,218E-03 0,01403313 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 1,218E-03 0,01396725 ! spleen development GO:0048536 24 13 1,000 1,218E-03 0,01390198 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,218E-03 0,01383732 ! digestive tract morphogenesis GO:0048546 31 13 1,000 1,218E-03 0,01377326 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! morphogenesis of a branching structure GO:0001763 116 52 2,000 1,22E-03 0,0137323 ! regulation of neuron apoptosis GO:0043523 117 53 2,000 1,289E-03 0,01444703 ! cartilage development GO:0051216 99 53 2,000 1,289E-03 0,01438106 ! regulation of cell shape GO:0008360 142 54 2,000 1,361E-03 0,01511341 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 1,361E-03 0,01504503 ! hair follicle morphogenesis GO:0031069 27 14 1,000 1,417E-03 0,0155933 ! fear response GO:0042596 34 14 1,000 1,417E-03 0,01552337 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 1,417E-03 0,01545407 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 37 14 1,000 1,417E-03 0,01538539 ! regulation of cellular pH GO:0030641 27 14 1,000 1,417E-03 0,01531731 ! regulation of RNA stability GO:0043487 33 14 1,000 1,417E-03 0,01524983 ! regulation of axon extension GO:0030516 43 14 1,000 1,417E-03 0,01518295 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 2,000 1,435E-03 0,01531214 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 1,435E-03 0,01524557 ! response to UV GO:0009411 120 55 2,000 1,435E-03 0,01517957 ! skeletal muscle fiber development GO:0048741 130 56 2,000 1,512E-03 0,01592292 ! regulation of bone remodeling GO:0046850 143 57 2,000 1,591E-03 0,01668641 ! positive regulation of caspase activity GO:0043280 108 57 2,000 1,591E-03 0,0166151 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 2,000 1,591E-03 0,0165444 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,631E-03 0,01688034 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,631E-03 0,01680911 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 1,631E-03 0,01673848 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,631E-03 0,01666845 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,631E-03 0,016599 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,631E-03 0,01653012 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 1,631E-03 0,01646182 ! muscle maintenance GO:0046716 26 15 1,000 1,631E-03 0,01639407 ! lymphocyte homeostasis GO:0002260 33 15 1,000 1,631E-03 0,01632688 ! regulation of actin filament length GO:0030832 118 58 2,000 1,673E-03 0,01668575 ! aging GO:0007568 112 58 2,000 1,673E-03 0,01661792 ! regulation of tissue remodeling GO:0034103 146 58 2,000 1,673E-03 0,01655064 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,859E-03 0,01830998 ! axon cargo transport GO:0008088 46 16 1,000 1,859E-03 0,01823645 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,859E-03 0,0181635 ! DNA replication initiation GO:0006270 28 16 1,000 1,859E-03 0,01809114 ! neuron recognition GO:0008038 40 16 1,000 1,859E-03 0,01801935 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,859E-03 0,01794812 ! positive regulation of secretion GO:0051047 110 61 2,000 1,935E-03 0,01860819 ! regulation of cellular component size GO:0032535 125 61 2,000 1,935E-03 0,01853522 ! cytokine-mediated signaling pathway GO:0019221 112 61 2,000 1,935E-03 0,01846281 ! metencephalon development GO:0022037 32 17 1,000 2,101E-03 0,01997188 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 2,101E-03 0,01989447 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 2,101E-03 0,01981766 ! regulation of protein binding GO:0043393 33 17 1,000 2,101E-03 0,01974144 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 2,101E-03 0,0196658 ! limbic system development GO:0021761 40 18 1,000 2,357E-03 0,02198157 ! adult walking behavior GO:0007628 36 18 1,000 2,357E-03 0,02189799 ! patterning of blood vessels GO:0001569 43 18 1,000 2,357E-03 0,02181504 ! heart looping GO:0001947 34 18 1,000 2,357E-03 0,02173272 ! regulation of viral genome replication GO:0045069 30 18 1,000 2,357E-03 0,02165102 ! epidermis morphogenesis GO:0048730 43 18 1,000 2,357E-03 0,02156993 ! glycine metabolic process GO:0006544 30 18 1,000 2,357E-03 0,02148944 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,357E-03 0,02140955 ! neural crest cell migration GO:0001755 41 18 1,000 2,357E-03 0,02133026 ! long-chain fatty acid transport GO:0015909 32 18 1,000 2,357E-03 0,02125155 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 2,357E-03 0,02117342 ! defense response to virus GO:0051607 43 18 1,000 2,357E-03 0,02109586 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 2,628E-03 0,02342986 ! pigmentation during development GO:0048066 42 19 1,000 2,628E-03 0,02334466 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 2,628E-03 0,02326008 ! detection of external stimulus GO:0009581 102 68 2,000 2,639E-03 0,02327859 ! adaptive immune response GO:0002250 126 68 2,000 2,639E-03 0,02319485 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of angiogenesis GO:0045766 50 20 1,000 2,912E-03 0,02549937 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,912E-03 0,0254083 ! protein amino acid acetylation GO:0006473 41 20 1,000 2,912E-03 0,02531788 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 2,912E-03 0,0252281 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 2,912E-03 0,02513896 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 2,912E-03 0,02505044 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 2,912E-03 0,02496254 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 2,912E-03 0,02487526 ! cell cycle checkpoint GO:0000075 145 71 2,000 2,984E-03 0,02539939 ! B cell activation GO:0042113 179 72 2,000 3,105E-03 0,02633462 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 3,21E-03 0,02713675 ! lipid phosphorylation GO:0046834 43 21 1,000 3,21E-03 0,02704318 ! ovarian follicle development GO:0001541 39 21 1,000 3,21E-03 0,02695025 ! cellular macromolecular complex disassembly GO:0034623 44 21 1,000 3,21E-03 0,02685795 ! microtubule-based transport GO:0010970 59 22 1,000 3,522E-03 0,02936551 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 3,522E-03 0,02926562 ! cellular response to starvation GO:0009267 37 22 1,000 3,522E-03 0,02916642 ! ureteric bud development GO:0001657 50 22 1,000 3,522E-03 0,02906788 ! renal system process GO:0003014 42 22 1,000 3,522E-03 0,02897001 ! positive regulation of locomotion GO:0040017 44 22 1,000 3,522E-03 0,0288728 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,522E-03 0,02877623 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 3,522E-03 0,02868031 ! peptidyl-serine modification GO:0018209 50 22 1,000 3,522E-03 0,02858503 ! response to cytokine stimulus GO:0034097 69 22 1,000 3,522E-03 0,02849038 ! gut development GO:0048565 44 22 1,000 3,522E-03 0,02839635 ! cell-matrix adhesion GO:0007160 181 76 2,000 3,617E-03 0,02906626 ! regulation of actin cytoskeleton organization GO:0032956 167 76 2,000 3,617E-03 0,02897097 ! lymphocyte differentiation GO:0030098 193 76 2,000 3,617E-03 0,02887629 ! phosphoinositide metabolic process GO:0030384 146 77 2,000 3,753E-03 0,02986176 ! regulation of catabolic process GO:0009894 173 77 2,000 3,753E-03 0,02976481 ! viral genome replication GO:0019079 44 23 1,000 3,847E-03 0,03041671 ! regulation of chemotaxis GO:0050920 45 23 1,000 3,847E-03 0,03031859 ! regeneration GO:0031099 42 23 1,000 3,847E-03 0,03022111 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 3,847E-03 0,03012424 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 1,000 3,847E-03 0,030028 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 3,847E-03 0,02993237 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 3,847E-03 0,02983735 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 3,847E-03 0,02974292 ! DNA modification GO:0006304 36 23 1,000 3,847E-03 0,0296491 ! fatty acid transport GO:0015908 47 23 1,000 3,847E-03 0,02955586 ! regulation of actin filament-based process GO:0032970 170 79 2,000 4,033E-03 0,03088693 ! protein oligomerization GO:0051259 149 79 2,000 4,033E-03 0,03079041 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 4,186E-03 0,0318575 ! pallium development GO:0021543 56 24 1,000 4,186E-03 0,03175856 ! oogenesis GO:0048477 44 24 1,000 4,186E-03 0,03166024 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 4,186E-03 0,03156252 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 4,186E-03 0,03146541 ! barbed-end actin filament capping GO:0051016 58 24 1,000 4,186E-03 0,03136889 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 1,000 4,186E-03 0,03127296 ! muscle cell differentiation GO:0042692 178 81 2,000 4,326E-03 0,03222159 ! cell-substrate adhesion GO:0031589 189 82 2,000 4,477E-03 0,03324642 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 4,538E-03 0,03359485 ! vasculogenesis GO:0001570 49 25 1,000 4,538E-03 0,03349336 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 4,538E-03 0,03339248 ! negative regulation of DNA replication GO:0008156 45 25 1,000 4,538E-03 0,0332922 ! receptor metabolic process GO:0043112 53 25 1,000 4,538E-03 0,03319252 ! regulation of behavior GO:0050795 48 25 1,000 4,538E-03 0,03309344 ! lymphocyte proliferation GO:0046651 55 25 1,000 4,538E-03 0,03299495 ! leukocyte homeostasis GO:0001776 50 25 1,000 4,538E-03 0,03289704 ! protein tetramerization GO:0051262 57 25 1,000 4,538E-03 0,03279971 ! T cell activation GO:0042110 189 84 2,000 4,789E-03 0,03451362 ! response to nutrient GO:0007584 135 84 2,000 4,789E-03 0,03441211 ! molting cycle process GO:0022404 52 26 1,000 4,903E-03 0,03512793 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 1,000 4,903E-03 0,03502522 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 4,903E-03 0,0349231 ! multicellular organismal response to stress GO:0033555 61 26 1,000 4,903E-03 0,03482158 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 4,903E-03 0,03472065 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,903E-03 0,0346203 ! neural crest cell development GO:0014032 59 26 1,000 4,903E-03 0,03452053 GO:0014033|neural crest cell differentiation, ! cellular response to hormone stimulus GO:0032870 182 85 2,000 4,95E-03 0,03474961 ! mitochondrion organization GO:0007005 159 87 2,000 5,281E-03 0,03696858 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 5,282E-03 0,03686559 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 5,282E-03 0,03676056 ! iron ion transport GO:0006826 65 27 1,000 5,282E-03 0,03665613 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 5,282E-03 0,03655228 ! response to starvation GO:0042594 47 27 1,000 5,282E-03 0,03644903 ! cellular response to nutrient levels GO:0031669 45 27 1,000 5,282E-03 0,03634636 ! leukocyte proliferation GO:0070661 59 27 1,000 5,282E-03 0,03624426 GO:0032943|mononuclear cell proliferation, ! regulation of DNA binding GO:0051101 167 89 2,000 5,625E-03 0,03849593 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 5,673E-03 0,03871237 ! protein amino acid acylation GO:0043543 59 28 1,000 5,673E-03 0,03860454 ! dendrite development GO:0016358 67 28 1,000 5,673E-03 0,0384973 ! base-excision repair GO:0006284 41 28 1,000 5,673E-03 0,03839066 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 5,673E-03 0,03828461 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 5,673E-03 0,03817914 ! gland development GO:0048732 220 91 2,000 5,983E-03 0,04015449 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 6,077E-03 0,04067555 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 6,077E-03 0,04056441 ! response to organic cyclic substance GO:0014070 58 29 1,000 6,077E-03 0,04045388 ! somitogenesis GO:0001756 52 29 1,000 6,077E-03 0,04034395 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 6,077E-03 0,04023462 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 6,077E-03 0,04012588 ! regulation of cell adhesion GO:0030155 241 92 2,000 6,167E-03 0,04060645 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 6,494E-03 0,04264874 ! negative regulation of protein complex assembly GO:0031333 68 30 1,000 6,494E-03 0,0425344 ! complement activation, classical pathway GO:0006958 51 30 1,000 6,494E-03 0,04242067 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 6,494E-03 0,04230755 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 6,494E-03 0,04219503 ! tissue homeostasis GO:0001894 50 30 1,000 6,494E-03 0,0420831 GO:0048871|multicellular organismal homeostasis, ! cell junction assembly GO:0034329 85 31 1,000 6,924E-03 0,04474876 ! ovulation cycle process GO:0022602 55 31 1,000 6,924E-03 0,04463069 ! male gonad development GO:0008584 56 31 1,000 6,924E-03 0,04451324 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 6,924E-03 0,04439641 ! response to heat GO:0009408 54 31 1,000 6,924E-03 0,04428018 ! regulation of protein localization GO:0032880 188 97 2,000 7,135E-03 0,04551418 ! collagen metabolic process GO:0032963 49 32 1,000 7,366E-03 0,04686306 ! spindle organization GO:0007051 50 32 1,000 7,366E-03 0,04674134 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 7,366E-03 0,04662024 ! metanephros development GO:0001656 81 32 1,000 7,366E-03 0,04649978 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 7,366E-03 0,04637993 ! ovulation cycle GO:0042698 57 32 1,000 7,366E-03 0,0462607 ! hindbrain development GO:0030902 65 32 1,000 7,366E-03 0,04614209 ! positive regulation of catabolic process GO:0009896 72 32 1,000 7,366E-03 0,04602408 ! regulation of pH GO:0006885 56 33 1,000 7,821E-03 0,04874036 ! regulation of axonogenesis GO:0050770 86 33 1,000 7,821E-03 0,04861634 ! leukocyte chemotaxis GO:0030595 55 33 1,000 7,821E-03 0,04849295 GO:0060326|cell chemotaxis, ! response to hydrogen peroxide GO:0042542 56 34 1,000 8,288E-03 0,05125871 ! post-embryonic development GO:0009791 76 34 1,000 8,288E-03 0,05112927 ! GPI anchor biosynthetic process GO:0006506 58 34 1,000 8,288E-03 0,05100048 ! cell fate specification GO:0001708 56 34 1,000 8,288E-03 0,05087234 ! serine family amino acid metabolic process GO:0009069 56 34 1,000 8,288E-03 0,05074484 ! adult locomotory behavior GO:0008344 62 34 1,000 8,288E-03 0,05061798 ! DNA damage checkpoint GO:0000077 78 35 1,000 8,767E-03 0,05341165 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 8,767E-03 0,05327878 ! GPI anchor metabolic process GO:0006505 61 35 1,000 8,767E-03 0,05314658 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 8,767E-03 0,05301502 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 8,767E-03 0,05288412 ! telencephalon development GO:0021537 81 35 1,000 8,767E-03 0,05275387 ! regulation of muscle development GO:0048634 82 36 1,000 9,259E-03 0,05557395 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 9,259E-03 0,05543774 ! positive regulation of cell development GO:0010720 85 36 1,000 9,259E-03 0,0553022 ! regulation of proteolysis GO:0030162 77 36 1,000 9,259E-03 0,05516732 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 9,259E-03 0,05503309 ! embryonic organ development GO:0048568 67 36 1,000 9,259E-03 0,05489951 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 9,762E-03 0,05774462 ! xenobiotic metabolic process GO:0006805 55 37 1,000 9,762E-03 0,05760514 ! cell junction organization GO:0034330 96 37 1,000 9,762E-03 0,05746633 ! female gonad development GO:0008585 71 37 1,000 9,762E-03 0,05732819 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01027736 0,06021007 ! regulation of protein stability GO:0031647 77 38 1,000 0,01027736 0,06006603 ! pigment metabolic process GO:0042440 87 38 1,000 0,01027736 0,05992267 ! neural tube formation GO:0001841 79 38 1,000 0,01027736 0,05978 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,01080457 0,0626973 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01080457 0,06254873 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,01080457 0,06240086 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 0,0113435 0,0653589 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 0,0113435 0,06520512 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,0113435 0,06505205 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 1,000 0,0113435 0,06489971 ! phosphoinositide biosynthetic process GO:0046489 77 41 1,000 0,01189406 0,06789061 ! feeding behavior GO:0007631 69 41 1,000 0,01189406 0,06773236 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,01189406 0,06757484 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01189406 0,06741805 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,01189406 0,06726199 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01245613 0,07027792 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,01245613 0,07011599 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,01245613 0,0699548 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01302964 0,0730078 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,01302964 0,07284073 ! monocarboxylic acid transport GO:0015718 93 43 1,000 0,01302964 0,07267443 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,01302964 0,07250888 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,01302964 0,07234409 ! segmentation GO:0035282 78 43 1,000 0,01302964 0,07218004 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,01302964 0,07201674 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,01361446 0,07507928 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,01361446 0,07491018 ! double-strand break repair GO:0006302 85 44 1,000 0,01361446 0,07474185 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,01421051 0,07783916 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,01421051 0,07766502 ! biopolymer methylation GO:0043414 91 45 1,000 0,01421051 0,07749166 ! female gamete generation GO:0007292 71 45 1,000 0,01421051 0,07731907 ! developmental growth GO:0048589 88 45 1,000 0,01421051 0,07714725 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,01481768 0,08026516 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01481768 0,08008758 ! leukocyte migration GO:0050900 75 46 1,000 0,01481768 0,07991079 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01481768 0,07973477 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01481768 0,07955953 ! neural tube development GO:0021915 91 47 1,000 0,01543588 0,08269703 ! cellular component disassembly GO:0022411 89 48 1,000 0,01606501 0,08587924 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01606501 0,08569173 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,01606501 0,08550503 ! male sex differentiation GO:0046661 93 48 1,000 0,01606501 0,08531915 ! methylation GO:0032259 97 48 1,000 0,01606501 0,08513408 ! protein homooligomerization GO:0051260 84 49 1,000 0,01670497 0,08833385 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,01735567 0,09157646 ! endocrine system development GO:0035270 109 50 1,000 0,01735567 0,0913791 ! regulation of ossification GO:0030278 123 50 1,000 0,01735567 0,09118259 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,01735567 0,09098691 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01735567 0,09079208 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,01735567 0,09059808 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,01735567 0,09040491 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,01801701 0,09365013 ! viral infectious cycle GO:0019058 104 51 1,000 0,01801701 0,0934513 ! response to temperature stimulus GO:0009266 84 51 1,000 0,01801701 0,09325331 ! positive regulation of binding GO:0051099 88 52 1,000 0,0186889 0,0965264 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,0186889 0,09632276 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,0186889 0,09611998 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,0186889 0,09591804 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,0186889 0,09571696 ! histone modification GO:0016570 104 52 1,000 0,0186889 0,09551671 ! amino acid activation GO:0043038 98 52 1,000 0,0186889 0,0953173 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of growth GO:0045927 96 53 1,000 0,01937124 0,09859156 ! chromatin remodeling GO:0006338 122 53 1,000 0,01937124 0,09838659 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,01937124 0,09818247 ! vesicle organization GO:0016050 127 53 1,000 0,01937124 0,09797919 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01995582 0,1007274 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01995582 0,10051971 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01995582 0,10031288 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01995582 0,1001069 ! neuron fate determination GO:0048664 7 5 0,000 0,01995582 0,09990176 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01995582 0,09969746 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01995582 0,099494 ! polyol transport GO:0015791 12 5 0,000 0,01995582 0,09929136 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01995582 0,09908955 ! response to superoxide GO:0000303 10 5 0,000 0,01995582 0,09888856 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01995582 0,09868838 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01995582 0,09848901 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01995582 0,09829044 ! female meiosis GO:0007143 10 5 0,000 0,01995582 0,09809268 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01995582 0,0978957 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01995582 0,09769952 ! hypothalamus development GO:0021854 9 5 0,000 0,01995582 0,09750412 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01995582 0,0973095 ! cobalt ion transport GO:0006824 11 5 0,000 0,01995582 0,09711566 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01995582 0,09692258 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01995582 0,09673028 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01995582 0,09653873 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01995582 0,09634794 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01995582 0,09615791 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01995582 0,09596862 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01995582 0,09578008 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01995582 0,09559227 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01995582 0,0954052 ! transposition GO:0032196 9 5 0,000 0,01995582 0,09521887 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01995582 0,09503325 ! negative chemotaxis GO:0050919 16 5 0,000 0,01995582 0,09484836 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01995582 0,09466419 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01995582 0,09448074 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01995582 0,09429799 ! behavioral response to pain GO:0048266 10 5 0,000 0,01995582 0,09411595 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01995582 0,0939346 ! Notch receptor processing GO:0007220 11 5 0,000 0,01995582 0,09375396 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01995582 0,09357401 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01995582 0,09339475 ! micturition GO:0060073 9 5 0,000 0,01995582 0,09321618 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01995582 0,09303828 ! copulation GO:0007620 9 5 0,000 0,01995582 0,09286107 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01995582 0,09268452 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01995582 0,09250865 ! bioluminescence GO:0008218 9 5 0,000 0,01995582 0,09233345 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01995582 0,0921589 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01995582 0,09198502 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01995582 0,09181179 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01995582 0,09163921 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01995582 0,09146728 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01995582 0,09129599 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01995582 0,09112535 ! grooming behavior GO:0007625 6 5 0,000 0,01995582 0,09095534 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01995582 0,09078596 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01995582 0,09061721 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01995582 0,09044909 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01995582 0,09028159 ! response to protozoan GO:0001562 13 5 0,000 0,01995582 0,09011471 ! lymph vessel development GO:0001945 10 5 0,000 0,01995582 0,08994845 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01995582 0,0897828 ! endochondral ossification GO:0001958 17 5 0,000 0,01995582 0,08961776 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01995582 0,08945332 ! single strand break repair GO:0000012 8 5 0,000 0,01995582 0,08928949 ! parathyroid gland development GO:0060017 14 5 0,000 0,01995582 0,08912625 ! anagen GO:0042640 7 5 0,000 0,01995582 0,08896361 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01995582 0,08880157 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01995582 0,08864011 ! cytokine secretion GO:0050663 15 5 0,000 0,01995582 0,08847924 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01995582 0,08831895 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01995582 0,08815924 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01995582 0,08800011 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01995582 0,08784155 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01995582 0,08768356 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01995582 0,08752614 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01995582 0,08736928 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01995582 0,08721299 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01995582 0,08705725 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01995582 0,08690207 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01995582 0,08674744 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01995582 0,08659336 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01995582 0,08643982 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01995582 0,08628683 ! valine metabolic process GO:0006573 12 5 0,000 0,01995582 0,08613438 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01995582 0,08598247 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01995582 0,08583109 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01995582 0,08568025 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01995582 0,08552993 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01995582 0,08538014 ! polyol catabolic process GO:0046174 9 5 0,000 0,01995582 0,08523087 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01995582 0,08508213 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01995582 0,0849339 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01995582 0,08478619 ! muscle cell migration GO:0014812 8 5 0,000 0,01995582 0,08463899 ! mitochondrial fission GO:0000266 8 5 0,000 0,01995582 0,0844923 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01995582 0,08434612 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01995582 0,08420045 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01995582 0,08405528 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01995582 0,0839106 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01995582 0,08376643 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01995582 0,08362274 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01995582 0,08347955 ! monocyte activation GO:0042117 10 5 0,000 0,01995582 0,08333685 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01995582 0,08319464 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01995582 0,08305291 ! response to food GO:0032094 6 5 0,000 0,01995582 0,08291167 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01995582 0,0827709 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01995582 0,08263061 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01995582 0,08249079 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01995582 0,08235145 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01995582 0,08221258 ! forebrain neuron development GO:0021884 13 5 0,000 0,01995582 0,08207417 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01995582 0,08193623 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01995582 0,08179876 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01995582 0,08166174 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01995582 0,08152518 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01995582 0,08138908 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01995582 0,08125343 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01995582 0,08111824 ! lipid glycosylation GO:0030259 7 5 0,000 0,01995582 0,08098349 ! nucleobase transport GO:0015851 6 5 0,000 0,01995582 0,08084919 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01995582 0,08071533 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01995582 0,08058192 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01995582 0,08044894 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01995582 0,08031641 ! basic amino acid transport GO:0015802 12 5 0,000 0,01995582 0,08018431 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01995582 0,08005264 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01995582 0,07992141 ! actin nucleation GO:0045010 11 5 0,000 0,01995582 0,0797906 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01995582 0,07966023 ! depurination GO:0045007 5 5 0,000 0,01995582 0,07953028 ! depyrimidination GO:0045008 10 5 0,000 0,01995582 0,07940075 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01995582 0,07927164 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01995582 0,07914295 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01995582 0,07901468 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01995582 0,07888683 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01995582 0,07875939 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01995582 0,07863235 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01995582 0,07850573 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01995582 0,07837952 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01995582 0,07825371 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01995582 0,0781283 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01995582 0,0780033 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01995582 0,07787869 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01995582 0,07775448 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01995582 0,07763067 ! response to arsenic GO:0046685 11 5 0,000 0,01995582 0,07750725 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01995582 0,07738422 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01995582 0,07726158 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01995582 0,07713933 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01995582 0,07701747 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01995582 0,07689599 ! response to mercury ion GO:0046689 8 5 0,000 0,01995582 0,0767749 ! response to cadmium ion GO:0046686 7 5 0,000 0,01995582 0,07665418 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01995582 0,07653385 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01995582 0,07641389 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01995582 0,0762943 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01995582 0,07617509 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01995582 0,07605626 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01995582 0,07593779 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01995582 0,07581969 ! decidualization GO:0046697 11 5 0,000 0,01995582 0,07570196 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01995582 0,07558459 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01995582 0,07546758 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01995582 0,07535094 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01995582 0,07523466 ! embryonic cleavage GO:0040016 6 5 0,000 0,01995582 0,07511874 ! peroxisome fission GO:0016559 5 5 0,000 0,01995582 0,07500317 ! histone demethylation GO:0016577 13 5 0,000 0,01995582 0,07488796 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01995582 0,0747731 ! mitotic recombination GO:0006312 9 5 0,000 0,01995582 0,07465859 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01995582 0,07454443 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01995582 0,07443063 ! metaphase plate congression GO:0051310 7 5 0,000 0,01995582 0,07431716 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01995582 0,07420405 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01995582 0,07409128 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01995582 0,07397885 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01995582 0,07386676 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01995582 0,07375501 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01995582 0,07364359 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01995582 0,07353252 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01995582 0,07342178 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01995582 0,07331137 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01995582 0,07320129 ! metaphase GO:0051323 11 5 0,000 0,01995582 0,07309154 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01995582 0,07298213 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01995582 0,07287303 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01995582 0,07276427 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01995582 0,07265583 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01995582 0,07254771 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01995582 0,07243991 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01995582 0,07233243 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01995582 0,07222527 ! response to redox state GO:0051775 6 5 0,000 0,01995582 0,07211843 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01995582 0,0720119 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01995582 0,07190569 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01995582 0,07179979 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01995582 0,07169421 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01995582 0,07158893 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01995582 0,07148396 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01995582 0,0713793 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01995582 0,07127494 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01995582 0,07117089 ! striatum development GO:0021756 14 5 0,000 0,01995582 0,07106714 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01995582 0,0709637 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01995582 0,07086055 ! glial cell migration GO:0008347 10 5 0,000 0,01995582 0,07075771 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01995582 0,07065516 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01995582 0,07055291 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01995582 0,07045095 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01995582 0,07034929 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01995582 0,07024792 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01995582 0,07014685 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01995582 0,07004606 ! neuroprotection GO:0043526 8 5 0,000 0,01995582 0,06994557 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01995582 0,06984536 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01995582 0,06974544 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01995582 0,0696458 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01995582 0,06954645 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01995582 0,06944738 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01995582 0,06934859 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01995582 0,06925008 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01995582 0,06915186 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01995582 0,06905391 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01995582 0,06895624 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01995582 0,06885884 ! spindle assembly GO:0051225 6 5 0,000 0,01995582 0,06876172 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01995582 0,06866487 GO:0022011|myelination in the peripheral nervous system, ! protein palmitoylation GO:0018345 12 5 0,000 0,01995582 0,0685683 ! drug metabolic process GO:0017144 7 5 0,000 0,01995582 0,06847199 ! stem cell division GO:0017145 11 5 0,000 0,01995582 0,06837596 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01995582 0,0682802 ! organ regeneration GO:0031100 7 5 0,000 0,01995582 0,0681847 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01995582 0,06808947 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01995582 0,0679945 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,02006395 0,06826772 ! protein amino acid lipidation GO:0006497 109 54 1,000 0,02006395 0,06817277 ! neuromuscular process GO:0050905 107 54 1,000 0,02006395 0,06807808 ! covalent chromatin modification GO:0016569 115 54 1,000 0,02006395 0,06798366 ! cell recognition GO:0008037 98 55 1,000 0,02076691 0,0702681 ! cell maturation GO:0048469 107 55 1,000 0,02076691 0,07017091 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,02076691 0,07007399 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,02076691 0,06997734 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02148005 0,07228068 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,02148005 0,07218125 ! regulation of DNA replication GO:0006275 105 56 1,000 0,02148005 0,0720821 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,02220327 0,07440686 ! heart morphogenesis GO:0003007 105 57 1,000 0,02220327 0,07430493 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,02220327 0,07420328 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,02220327 0,07410191 ! lipoprotein biosynthetic process GO:0042158 115 58 1,000 0,02293649 0,07644452 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02389927 0,07954484 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02389927 0,07943661 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02389927 0,07932868 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02389927 0,07922105 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02389927 0,0791137 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02389927 0,07900665 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02389927 0,07889988 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02389927 0,0787934 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02389927 0,07868721 ! response to oxygen radical GO:0000305 11 6 0,000 0,02389927 0,07858131 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02389927 0,07847569 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02389927 0,07837035 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02389927 0,0782653 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02389927 0,07816052 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02389927 0,07805603 ! forebrain regionalization GO:0021871 9 6 0,000 0,02389927 0,07795182 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02389927 0,07784788 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02389927 0,07774422 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02389927 0,07764084 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02389927 0,07753773 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02389927 0,0774349 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02389927 0,07733233 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02389927 0,07723004 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02389927 0,07712802 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02389927 0,07702627 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02389927 0,07692478 ! malate metabolic process GO:0006108 13 6 0,000 0,02389927 0,07682357 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02389927 0,07672262 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02389927 0,07662193 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02389927 0,07652151 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02389927 0,07642135 ! protein refolding GO:0042026 15 6 0,000 0,02389927 0,07632145 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02389927 0,07622182 ! opsonization GO:0008228 8 6 0,000 0,02389927 0,07612244 ! mating behavior GO:0007617 7 6 0,000 0,02389927 0,07602332 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02389927 0,07592446 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02389927 0,07582586 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02389927 0,07572751 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02389927 0,07562942 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02389927 0,07553158 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02389927 0,07543399 ! toxin metabolic process GO:0009404 11 6 0,000 0,02389927 0,07533666 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02389927 0,07523958 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02389927 0,07514274 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02389927 0,07504616 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02389927 0,07494982 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02389927 0,07485373 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02389927 0,07475789 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02389927 0,07466229 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02389927 0,07456694 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02389927 0,07447183 ! thymic T cell selection GO:0045061 16 6 0,000 0,02389927 0,07437696 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02389927 0,07428233 ! protein lipoylation GO:0009249 10 6 0,000 0,02389927 0,07418794 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02389927 0,0740938 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02389927 0,07399989 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02389927 0,07390622 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02389927 0,07381278 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02389927 0,07371958 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02389927 0,07362662 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02389927 0,07353389 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02389927 0,0734414 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02389927 0,07334913 ! hyperosmotic response GO:0006972 10 6 0,000 0,02389927 0,0732571 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02389927 0,0731653 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02389927 0,07307373 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02389927 0,07298239 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02389927 0,07289128 ! urea metabolic process GO:0019627 7 6 0,000 0,02389927 0,07280039 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02389927 0,07270973 ! neutrophil activation GO:0042119 7 6 0,000 0,02389927 0,07261929 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02389927 0,07252908 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02389927 0,0724391 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02389927 0,07234933 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02389927 0,07225979 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02389927 0,07217047 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02389927 0,07208137 ! neuron apoptosis GO:0051402 15 6 0,000 0,02389927 0,07199249 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02389927 0,07190383 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02389927 0,07181539 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02389927 0,07172716 ! carnitine transport GO:0015879 10 6 0,000 0,02389927 0,07163915 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02389927 0,07155136 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02389927 0,07146378 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02389927 0,07137642 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02389927 0,07128927 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02389927 0,07120233 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02389927 0,0711156 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02389927 0,07102909 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02389927 0,07094278 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02389927 0,07085669 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02389927 0,0707708 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02389927 0,07068512 ! response to UV-C GO:0010225 14 6 0,000 0,02389927 0,07059965 ! astrocyte development GO:0014002 16 6 0,000 0,02389927 0,07051439 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02389927 0,07042933 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02389927 0,07034447 ! interaction with symbiont GO:0051702 14 6 0,000 0,02389927 0,07025982 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02389927 0,07017537 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02389927 0,07009113 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02389927 0,07000709 ! response to copper ion GO:0046688 10 6 0,000 0,02389927 0,06992325 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02389927 0,06983961 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02389927 0,06975617 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02389927 0,06967293 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02389927 0,06958988 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02389927 0,06950704 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02389927 0,06942439 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02389927 0,06934194 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02389927 0,06925968 ! hair follicle maturation GO:0048820 8 6 0,000 0,02389927 0,06917762 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02389927 0,06909575 ! Schwann cell development GO:0014044 15 6 0,000 0,02389927 0,06901408 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02389927 0,0689326 ! response to pheromone GO:0019236 6 6 0,000 0,02389927 0,06885131 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02389927 0,06877021 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02389927 0,06868931 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02389927 0,06860859 ! subpallium development GO:0021544 15 6 0,000 0,02389927 0,06852806 ! neural tube patterning GO:0021532 8 6 0,000 0,02389927 0,06844773 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02389927 0,06836758 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02389927 0,06828762 ! G2 phase GO:0051319 16 6 0,000 0,02389927 0,06820784 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02389927 0,06812825 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02389927 0,06804885 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02389927 0,06796963 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02389927 0,06789059 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02389927 0,06781174 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02389927 0,06773308 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02389927 0,06765459 ! receptor internalization GO:0031623 11 6 0,000 0,02389927 0,06757629 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02389927 0,06749816 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02389927 0,06742022 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02389927 0,06734246 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02389927 0,06726487 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02389927 0,06718747 ! protein destabilization GO:0031648 9 6 0,000 0,02389927 0,06711024 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02389927 0,06703319 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02389927 0,06695632 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02389927 0,06687962 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02389927 0,0668031 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02389927 0,06672676 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02389927 0,06665058 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02389927 0,06657459 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02389927 0,06649876 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02389927 0,06642311 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02389927 0,06634763 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02389927 0,06627232 ! neural plate development GO:0001840 9 6 0,000 0,02389927 0,06619718 ! catecholamine transport GO:0051937 9 6 0,000 0,02389927 0,06612221 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02389927 0,06604741 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02389927 0,06597278 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02389927 0,06589832 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02389927 0,06582403 ! maternal placenta development GO:0001893 12 6 0,000 0,02389927 0,0657499 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02389927 0,06567594 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02389927 0,06560215 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02389927 0,06552852 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02389927 0,06545506 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02389927 0,06538176 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02389927 0,06530863 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02389927 0,06523566 GO:0055081|anion homeostasis, ! lipid modification GO:0030258 112 60 1,000 0,02443252 0,06661678 ! adult behavior GO:0030534 104 60 1,000 0,02443252 0,06654251 ! kidney development GO:0001822 133 60 1,000 0,02443252 0,06646841 ! viral reproductive process GO:0022415 132 62 1,000 0,02596742 0,07056553 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,02596742 0,07048712 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,02674923 0,07252871 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,02674923 0,0724483 ! glycerophospholipid biosynthetic process GO:0046474 116 64 1,000 0,02754049 0,07450877 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,02754049 0,07442635 ! tRNA transcription GO:0009304 17 7 0,000 0,02782696 0,07511742 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02782696 0,07503451 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02782696 0,07495178 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02782696 0,07486924 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02782696 0,07478687 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02782696 0,07470469 ! sleep GO:0030431 16 7 0,000 0,02782696 0,07462269 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02782696 0,07454086 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02782696 0,07445922 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02782696 0,07437776 ! prostate gland development GO:0030850 14 7 0,000 0,02782696 0,07429647 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02782696 0,07421536 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02782696 0,07413443 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02782696 0,07405367 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02782696 0,07397309 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02782696 0,07389268 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02782696 0,07381245 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02782696 0,0737324 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02782696 0,07365251 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02782696 0,0735728 ! glycolipid transport GO:0046836 11 7 0,000 0,02782696 0,07349326 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02782696 0,0734139 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02782696 0,0733347 ! neuron adhesion GO:0007158 14 7 0,000 0,02782696 0,07325568 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02782696 0,07317682 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02782696 0,07309814 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02782696 0,07301962 ! pericardium development GO:0060039 16 7 0,000 0,02782696 0,07294128 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02782696 0,0728631 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02782696 0,07278508 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02782696 0,07270724 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02782696 0,07262956 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02782696 0,07255205 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02782696 0,0724747 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02782696 0,07239752 ! rhythmic behavior GO:0007622 17 7 0,000 0,02782696 0,0723205 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02782696 0,07224364 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02782696 0,07216695 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02782696 0,07209042 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02782696 0,07201406 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02782696 0,07193785 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02782696 0,07186181 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02782696 0,07178592 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02782696 0,0717102 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02782696 0,07163464 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02782696 0,07155923 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02782696 0,07148398 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02782696 0,0714089 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02782696 0,07133397 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02782696 0,07125919 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02782696 0,07118457 ! spinal cord patterning GO:0021511 14 7 0,000 0,02782696 0,07111011 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02782696 0,07103581 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02782696 0,07096166 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02782696 0,07088766 ! adrenal gland development GO:0030325 17 7 0,000 0,02782696 0,07081382 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02782696 0,07074013 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02782696 0,0706666 ! ovulation GO:0030728 10 7 0,000 0,02782696 0,07059322 ! adenohypophysis development GO:0021984 11 7 0,000 0,02782696 0,07051999 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02782696 0,07044691 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02782696 0,07037398 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02782696 0,07030121 ! microtubule nucleation GO:0007020 21 7 0,000 0,02782696 0,07022858 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02782696 0,07015611 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02782696 0,07008378 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02782696 0,07001161 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02782696 0,06993958 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02782696 0,0698677 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02782696 0,06979596 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02782696 0,06972438 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02782696 0,06965294 ! galactose metabolic process GO:0006012 13 7 0,000 0,02782696 0,06958165 ! vesicle fusion GO:0006906 20 7 0,000 0,02782696 0,0695105 ! response to dietary excess GO:0002021 8 7 0,000 0,02782696 0,0694395 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02782696 0,06936864 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02782696 0,06929793 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02782696 0,06922736 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02782696 0,06915694 ! nucleoside transport GO:0015858 11 7 0,000 0,02782696 0,06908666 ! nucleoside salvage GO:0043174 11 7 0,000 0,02782696 0,06901652 GO:0006166|purine ribonucleoside salvage, ! male sex determination GO:0030238 15 7 0,000 0,02782696 0,06894652 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02782696 0,06887667 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02782696 0,06880695 ! parturition GO:0007567 16 7 0,000 0,02782696 0,06873738 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02782696 0,06866795 ! rRNA modification GO:0000154 14 7 0,000 0,02782696 0,06859866 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02782696 0,0685295 ! spindle checkpoint GO:0031577 16 7 0,000 0,02782696 0,06846049 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02782696 0,06839162 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02782696 0,06832288 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02782696 0,06825429 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02782696 0,06818583 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02782696 0,0681175 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02782696 0,06804932 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02782696 0,06798127 ! fibrinolysis GO:0042730 11 7 0,000 0,02782696 0,06791336 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02782696 0,06784558 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02782696 0,06777793 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02782696 0,06771043 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02782696 0,06764305 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02782696 0,06757581 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02782696 0,06750871 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02782696 0,06744173 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02782696 0,06737489 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02782696 0,06730819 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02782696 0,06724161 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02782696 0,06717517 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02782696 0,06710885 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02782696 0,06704267 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02782696 0,06697662 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02782696 0,0669107 ! histone ubiquitination GO:0016574 9 7 0,000 0,02782696 0,06684491 ! regulation of meiosis GO:0040020 12 7 0,000 0,02782696 0,06677924 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02782696 0,06671371 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02782696 0,0666483 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02782696 0,06658303 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02782696 0,06651788 ! transcription termination GO:0006353 14 7 0,000 0,02782696 0,06645285 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02782696 0,06638796 ! anaphase GO:0051322 18 7 0,000 0,02782696 0,06632319 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02782696 0,06625855 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02782696 0,06619403 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02782696 0,06612964 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02782696 0,06606537 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,02782696 0,06600123 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02782696 0,06593722 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02782696 0,06587332 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02782696 0,06580955 ! antibiotic transport GO:0042891 9 7 0,000 0,02782696 0,06574591 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02782696 0,06568239 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02782696 0,06561899 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02782696 0,06555571 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02782696 0,06549255 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02782696 0,06542952 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02782696 0,0653666 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02782696 0,06530381 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02782696 0,06524114 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02782696 0,06517859 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02782696 0,06511616 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02782696 0,06505385 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02782696 0,06499165 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02782696 0,06492958 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02782696 0,06486762 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02782696 0,06480579 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02782696 0,06474407 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02782696 0,06468246 ! muscle adaptation GO:0043500 13 7 0,000 0,02782696 0,06462098 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02782696 0,06455961 ! retina homeostasis GO:0001895 12 7 0,000 0,02782696 0,06449836 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02782696 0,06443722 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02782696 0,0643762 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02782696 0,0643153 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02782696 0,06425451 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,02834112 0,06537993 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,02834112 0,06531825 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,02834112 0,06525669 GO:0048609|reproductive process in a multicellular organism, ! ear development GO:0043583 114 66 1,000 0,02915102 0,06705833 ! gonad development GO:0008406 115 66 1,000 0,02915102 0,06699524 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,02997012 0,06881297 GO:0035113|embryonic appendage morphogenesis, ! secondary metabolic process GO:0019748 125 67 1,000 0,02997012 0,06874835 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,02997012 0,06868386 ! viral reproduction GO:0016032 142 68 1,000 0,03079832 0,07051574 ! cell projection assembly GO:0030031 138 68 1,000 0,03079832 0,07044971 ! urogenital system development GO:0001655 149 69 1,000 0,03163554 0,07229713 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,03163554 0,07222956 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,03163554 0,07216212 ! developmental maturation GO:0021700 128 69 1,000 0,03163554 0,0720948 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03173896 0,07226308 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03173896 0,0721958 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,03173896 0,07212864 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03173896 0,0720616 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03173896 0,07199469 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03173896 0,07192791 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03173896 0,07186125 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03173896 0,07179471 ! male meiosis GO:0007140 9 8 0,000 0,03173896 0,07172829 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03173896 0,071662 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03173896 0,07159583 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03173896 0,07152978 ! meiotic prophase I GO:0007128 14 8 0,000 0,03173896 0,07146386 ! response to zinc ion GO:0010043 12 8 0,000 0,03173896 0,07139805 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03173896 0,07133237 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03173896 0,07126681 ! oligopeptide transport GO:0006857 16 8 0,000 0,03173896 0,07120136 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03173896 0,07113604 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03173896 0,07107084 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03173896 0,07100576 ! signal peptide processing GO:0006465 12 8 0,000 0,03173896 0,07094079 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03173896 0,07087595 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03173896 0,07081122 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03173896 0,07074661 ! succinate metabolic process GO:0006105 17 8 0,000 0,03173896 0,07068212 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03173896 0,07061775 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03173896 0,07055349 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03173896 0,07048935 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03173896 0,07042533 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03173896 0,07036142 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03173896 0,07029763 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03173896 0,07023395 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03173896 0,07017039 ! reflex GO:0060004 17 8 0,000 0,03173896 0,07010695 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03173896 0,07004362 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03173896 0,0699804 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03173896 0,0699173 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03173896 0,06985431 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03173896 0,06979144 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03173896 0,06972867 ! histidine catabolic process GO:0006548 10 8 0,000 0,03173896 0,06966602 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03173896 0,06960349 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03173896 0,06954106 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03173896 0,06947875 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03173896 0,06941655 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03173896 0,06935446 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03173896 0,06929248 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03173896 0,06923061 ! macrophage activation GO:0042116 13 8 0,000 0,03173896 0,06916885 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03173896 0,06910721 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03173896 0,06904567 ! purine salvage GO:0043101 12 8 0,000 0,03173896 0,06898424 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03173896 0,06892292 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03173896 0,06886171 ! osteoblast development GO:0002076 17 8 0,000 0,03173896 0,06880061 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03173896 0,06873961 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03173896 0,06867873 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03173896 0,06861795 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03173896 0,06855728 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03173896 0,06849672 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03173896 0,06843626 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03173896 0,06837591 ! intermediate filament organization GO:0045109 12 8 0,000 0,03173896 0,06831567 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03173896 0,06825553 ! cellular extravasation GO:0045123 13 8 0,000 0,03173896 0,0681955 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03173896 0,06813558 ! response to antibiotic GO:0046677 11 8 0,000 0,03173896 0,06807575 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03173896 0,06801604 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03173896 0,06795643 ! DNA topological change GO:0006265 12 8 0,000 0,03173896 0,06789692 ! response to tropane GO:0014073 15 8 0,000 0,03173896 0,06783752 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,03173896 0,06777822 ! melanosome transport GO:0032402 13 8 0,000 0,03173896 0,06771903 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03173896 0,06765993 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03173896 0,06760095 ! mast cell activation GO:0045576 14 8 0,000 0,03173896 0,06754206 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03173896 0,06748328 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03173896 0,0674246 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03173896 0,06736602 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03173896 0,06730754 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03173896 0,06724916 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03173896 0,06719089 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03173896 0,06713271 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03173896 0,06707464 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03173896 0,06701667 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03173896 0,0669588 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03173896 0,06690102 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03173896 0,06684335 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03173896 0,06678578 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03173896 0,0667283 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03173896 0,06667092 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03173896 0,06661365 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03173896 0,06655647 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03173896 0,06649939 ! hormone catabolic process GO:0042447 17 8 0,000 0,03173896 0,0664424 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03173896 0,06638552 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03173896 0,06632873 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03173896 0,06627204 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03173896 0,06621544 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03173896 0,06615895 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03173896 0,06610254 ! adult feeding behavior GO:0008343 10 8 0,000 0,03173896 0,06604624 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03173896 0,06599003 ! ATP catabolic process GO:0006200 11 8 0,000 0,03173896 0,06593392 ! blastocyst growth GO:0001832 19 8 0,000 0,03173896 0,0658779 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03173896 0,06582197 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03173896 0,06576614 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03173896 0,06571041 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03173896 0,06565477 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03173896 0,06559923 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03173896 0,06554377 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03173896 0,06548842 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03173896 0,06543315 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03173896 0,06537798 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03173896 0,0653229 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03173896 0,06526792 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03173896 0,06521302 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03173896 0,06515822 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03173896 0,06510351 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03173896 0,0650489 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03173896 0,06499437 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03173896 0,06493994 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03173896 0,06488559 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03173896 0,06483134 ! germ cell development GO:0007281 133 70 1,000 0,0324817 0,06629306 ! activation of immune response GO:0002253 120 70 1,000 0,0324817 0,06623772 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,0324817 0,06618248 ! appendage morphogenesis GO:0035107 150 72 1,000 0,03420049 0,06962649 GO:0035108|limb morphogenesis, ! actin filament organization GO:0007015 167 72 1,000 0,03420049 0,06956851 ! appendage development GO:0048736 151 73 1,000 0,03507295 0,07128387 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 1,000 0,03507295 0,07122461 ! axon extension GO:0048675 16 9 0,000 0,03563533 0,07230657 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03563533 0,07224657 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03563533 0,07218666 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03563533 0,07212685 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03563533 0,07206715 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03563533 0,07200754 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03563533 0,07194803 ! reproductive behavior GO:0019098 22 9 0,000 0,03563533 0,07188861 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03563533 0,0718293 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03563533 0,07177008 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03563533 0,07171096 ! UTP metabolic process GO:0046051 10 9 0,000 0,03563533 0,07165194 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03563533 0,07159302 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03563533 0,07153419 ! artery development GO:0060840 25 9 0,000 0,03563533 0,07147546 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03563533 0,07141683 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03563533 0,07135829 ! equilibrioception GO:0050957 20 9 0,000 0,03563533 0,07129985 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03563533 0,0712415 ! chemosensory behavior GO:0007635 21 9 0,000 0,03563533 0,07118325 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03563533 0,07112509 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03563533 0,07106703 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03563533 0,07100906 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03563533 0,07095119 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03563533 0,07089341 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03563533 0,07083573 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03563533 0,07077814 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03563533 0,07072064 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03563533 0,07066324 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03563533 0,07060593 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03563533 0,07054871 ! protein targeting to ER GO:0045047 25 9 0,000 0,03563533 0,07049159 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03563533 0,07043456 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03563533 0,07037762 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03563533 0,07032077 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03563533 0,07026401 ! endosome organization GO:0007032 20 9 0,000 0,03563533 0,07020735 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03563533 0,07015077 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03563533 0,07009429 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03563533 0,0700379 ! mannose metabolic process GO:0006013 13 9 0,000 0,03563533 0,0699816 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03563533 0,06992539 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03563533 0,06986927 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03563533 0,06981324 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03563533 0,0697573 ! receptor clustering GO:0043113 20 9 0,000 0,03563533 0,06970145 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03563533 0,06964569 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03563533 0,06959002 ! retinol metabolic process GO:0042572 20 9 0,000 0,03563533 0,06953443 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03563533 0,06947894 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03563533 0,06942353 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03563533 0,06936822 ! macrophage differentiation GO:0030225 15 9 0,000 0,03563533 0,06931299 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03563533 0,06925785 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03563533 0,06920279 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03563533 0,06914782 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03563533 0,06909295 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03563533 0,06903815 ! response to amine stimulus GO:0014075 13 9 0,000 0,03563533 0,06898345 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03563533 0,06892883 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03563533 0,0688743 ! erythrocyte development GO:0048821 17 9 0,000 0,03563533 0,06881985 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03563533 0,06876549 ! renal water homeostasis GO:0003091 15 9 0,000 0,03563533 0,06871122 ! postreplication repair GO:0006301 25 9 0,000 0,03563533 0,06865703 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03563533 0,06860292 ! icosanoid secretion GO:0032309 15 9 0,000 0,03563533 0,06854891 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03563533 0,06849497 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03563533 0,06844113 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03563533 0,06838736 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03563533 0,06833368 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03563533 0,06828009 ! sterol catabolic process GO:0016127 14 9 0,000 0,03563533 0,06822658 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03563533 0,06817315 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03563533 0,06811981 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03563533 0,06806655 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03563533 0,06801337 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03563533 0,06796027 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03563533 0,06790726 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03563533 0,06785433 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03563533 0,06780149 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03563533 0,06774872 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03563533 0,06769604 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03563533 0,06764344 ! purine base metabolic process GO:0006144 25 9 0,000 0,03563533 0,06759093 ! pigment granule transport GO:0051904 17 9 0,000 0,03563533 0,06753849 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03563533 0,06748613 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03563533 0,06743386 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03563533 0,06738167 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03563533 0,06732955 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03563533 0,06727752 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03563533 0,06722557 ! mitochondrion localization GO:0051646 18 9 0,000 0,03563533 0,0671737 ! acute inflammatory response GO:0002526 118 74 1,000 0,03595401 0,06772216 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,03684359 0,06934429 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 1,000 0,03684359 0,06929091 ! reproductive structure development GO:0048608 131 75 1,000 0,03684359 0,0692376 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,03684359 0,06918439 ! axon guidance GO:0007411 162 75 1,000 0,03684359 0,06913125 ! rhythmic process GO:0048511 142 75 1,000 0,03684359 0,06907819 ! regulation of blood pressure GO:0008217 134 76 1,000 0,03774161 0,07070763 ! amine catabolic process GO:0009310 136 77 1,000 0,03864798 0,0723502 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03951613 0,07391876 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03951613 0,0738622 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03951613 0,07380573 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03951613 0,07374935 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03951613 0,07369305 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03951613 0,07363684 ! associative learning GO:0008306 21 10 0,000 0,03951613 0,07358072 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03951613 0,07352468 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03951613 0,07346872 ! phosphate transport GO:0006817 24 10 0,000 0,03951613 0,07341285 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03951613 0,07335707 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03951613 0,07330137 ! CTP metabolic process GO:0046036 11 10 0,000 0,03951613 0,07324575 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 0,000 0,03951613 0,07319022 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03951613 0,07313477 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03951613 0,07307941 ! social behavior GO:0035176 29 10 0,000 0,03951613 0,07302413 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03951613 0,07296893 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03951613 0,07291382 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03951613 0,07285879 ! androgen metabolic process GO:0008209 17 10 0,000 0,03951613 0,07280385 ! phospholipid efflux GO:0033700 19 10 0,000 0,03951613 0,07274898 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03951613 0,0726942 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03951613 0,0726395 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03951613 0,07258489 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03951613 0,07253035 ! pathogenesis GO:0009405 17 10 0,000 0,03951613 0,0724759 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03951613 0,07242153 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03951613 0,07236724 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03951613 0,07231303 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03951613 0,07225891 ! endoderm development GO:0007492 18 10 0,000 0,03951613 0,07220486 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03951613 0,0721509 ! arginine catabolic process GO:0006527 17 10 0,000 0,03951613 0,07209701 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03951613 0,07204321 ! proline metabolic process GO:0006560 13 10 0,000 0,03951613 0,07198949 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03951613 0,07193584 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03951613 0,07188228 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03951613 0,07182879 ! V(D)J recombination GO:0033151 34 10 0,000 0,03951613 0,07177539 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03951613 0,07172207 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03951613 0,07166882 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03951613 0,07161565 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03951613 0,07156257 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03951613 0,07150956 ! multicellular organism growth GO:0035264 19 10 0,000 0,03951613 0,07145663 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03951613 0,07140377 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03951613 0,071351 ! ruffle organization GO:0031529 17 10 0,000 0,03951613 0,0712983 ! epithelial cell development GO:0002064 21 10 0,000 0,03951613 0,07124568 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03951613 0,07119314 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03951613 0,07114068 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03951613 0,07108829 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03951613 0,07103598 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03951613 0,07098375 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,03951613 0,07093159 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03951613 0,07087952 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03951613 0,07082751 ! brain morphogenesis GO:0048854 23 10 0,000 0,03951613 0,07077559 ! segment specification GO:0007379 15 10 0,000 0,03951613 0,07072374 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03951613 0,07067196 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03951613 0,07062026 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03951613 0,07056864 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03951613 0,07051709 ! response to dsRNA GO:0043331 23 10 0,000 0,03951613 0,07046562 ! DNA ligation GO:0006266 18 10 0,000 0,03951613 0,07041422 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03951613 0,0703629 ! melanosome localization GO:0032400 16 10 0,000 0,03951613 0,07031165 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03951613 0,07026048 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03951613 0,07020938 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03951613 0,07015836 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03951613 0,07010741 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03951613 0,07005653 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03951613 0,07000573 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03951613 0,069955 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03951613 0,06990434 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03951613 0,06985376 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03951613 0,06980325 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03951613 0,06975282 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03951613 0,06970246 ! salivary gland development GO:0007431 28 10 0,000 0,03951613 0,06965216 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03951613 0,06960195 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03951613 0,0695518 ! midbrain development GO:0030901 14 10 0,000 0,03951613 0,06950173 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03951613 0,06945173 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03951613 0,0694018 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03951613 0,06935194 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03951613 0,06930215 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03951613 0,06925244 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03951613 0,0692028 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03951613 0,06915322 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03951613 0,06910372 ! detection of calcium ion GO:0005513 24 10 0,000 0,03951613 0,06905429 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03951613 0,06900493 ! blastocyst formation GO:0001825 18 10 0,000 0,03951613 0,06895564 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03951613 0,06890642 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03951613 0,06885728 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03951613 0,0688082 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03951613 0,06875919 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03951613 0,06871025 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,03956263 0,06874218 ! antigen processing and presentation GO:0019882 117 78 1,000 0,03956263 0,06869332 ! blood coagulation GO:0007596 151 79 1,000 0,04048547 0,07024575 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,04048547 0,07019589 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,04141643 0,07175911 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,04141643 0,07170825 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,04141643 0,07165747 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,04141643 0,07160676 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04338142 0,07495106 ! respiratory burst GO:0045730 17 11 0,000 0,04338142 0,07489809 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04338142 0,0748452 ! neuron fate specification GO:0048665 18 11 0,000 0,04338142 0,07479238 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04338142 0,07473963 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04338142 0,07468696 ! thyroid gland development GO:0030878 26 11 0,000 0,04338142 0,07463437 ! synapsis GO:0007129 14 11 0,000 0,04338142 0,07458185 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04338142 0,0745294 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04338142 0,07447702 ! response to pain GO:0048265 27 11 0,000 0,04338142 0,07442472 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04338142 0,07437249 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,04338142 0,07432034 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,04338142 0,07426826 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04338142 0,07421625 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04338142 0,07416431 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04338142 0,07411245 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04338142 0,07406066 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04338142 0,07400894 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04338142 0,07395729 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04338142 0,07390572 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04338142 0,07385422 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04338142 0,07380279 ! UV protection GO:0009650 20 11 0,000 0,04338142 0,07375143 ! adult heart development GO:0007512 16 11 0,000 0,04338142 0,07370014 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04338142 0,07364892 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04338142 0,07359778 ! macroautophagy GO:0016236 19 11 0,000 0,04338142 0,07354671 ! temperature homeostasis GO:0001659 18 11 0,000 0,04338142 0,0734957 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04338142 0,07344477 ! regulation of organ growth GO:0046620 14 11 0,000 0,04338142 0,07339391 ! pigment granule localization GO:0051875 20 11 0,000 0,04338142 0,07334312 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04338142 0,07329239 ! vasoconstriction GO:0042310 20 11 0,000 0,04338142 0,07324174 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04338142 0,07319116 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04338142 0,07314065 ! embryonic axis specification GO:0000578 19 11 0,000 0,04338142 0,07309021 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04338142 0,07303984 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04338142 0,07298953 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04338142 0,0729393 ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04338142 0,07288914 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04338142 0,07283904 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04338142 0,07278901 ! prophase GO:0051324 17 11 0,000 0,04338142 0,07273905 ! nucleosome positioning GO:0016584 15 11 0,000 0,04338142 0,07268916 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04338142 0,07263934 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04338142 0,07258959 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04338142 0,07253991 ! acid secretion GO:0046717 20 11 0,000 0,04338142 0,07249029 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04338142 0,07244074 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04338142 0,07239126 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04338142 0,07234184 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04338142 0,0722925 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04338142 0,07224322 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,04338142 0,07219401 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04338142 0,07214486 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04338142 0,07209578 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04338142 0,07204677 ! embryonic gut development GO:0048566 19 11 0,000 0,04338142 0,07199783 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04338142 0,07194895 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04338142 0,07190014 ! activation of innate immune response GO:0002218 16 11 0,000 0,04338142 0,07185139 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04338142 0,07180271 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04338142 0,0717541 ! lysogeny GO:0030069 22 11 0,000 0,04338142 0,07170555 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04338142 0,07165707 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04338142 0,07160865 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04338142 0,0715603 ! nucleus localization GO:0051647 22 11 0,000 0,04338142 0,07151201 ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,04425721 0,07290652 ! response to metal ion GO:0010038 158 84 1,000 0,04521985 0,07444211 ! hemostasis GO:0007599 165 85 1,000 0,0461902 0,07598833 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,04723126 0,0776487 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,04723126 0,07759648 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,04723126 0,07754433 ! virus-host interaction GO:0019048 30 12 0,000 0,04723126 0,07749226 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,04723126 0,07744025 ! mating GO:0007618 17 12 0,000 0,04723126 0,07738831 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04723126 0,07733644 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,04723126 0,07728464 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,04723126 0,07723291 ! T cell proliferation GO:0042098 32 12 0,000 0,04723126 0,07718125 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04723126 0,07712966 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,04723126 0,07707813 ! ventral spinal cord development GO:0021517 25 12 0,000 0,04723126 0,07702668 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,04723126 0,0769753 ! drug transport GO:0015893 16 12 0,000 0,04723126 0,07692398 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,04723126 0,07687273 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,04723126 0,07682155 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,04723126 0,07677044 ! polyamine metabolic process GO:0006595 18 12 0,000 0,04723126 0,07671939 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,04723126 0,07666842 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,04723126 0,07661751 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,04723126 0,07656667 ! lipid digestion GO:0044241 21 12 0,000 0,04723126 0,07651589 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,04723126 0,07646519 ! entry into host cell GO:0030260 34 12 0,000 0,04723126 0,07641455 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04723126 0,07636398 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,04723126 0,07631347 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,04723126 0,07626303 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04723126 0,07621266 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,04723126 0,07616236 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,04723126 0,07611212 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,04723126 0,07606194 ! snRNA metabolic process GO:0016073 30 12 0,000 0,04723126 0,07601184 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,04723126 0,0759618 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,04723126 0,07591182 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04723126 0,07586191 ! cranial nerve development GO:0021545 23 12 0,000 0,04723126 0,07581207 ! fucose catabolic process GO:0019317 25 12 0,000 0,04723126 0,07576229 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,04723126 0,07571258 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,04723126 0,07566293 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04723126 0,07561335 ! zymogen activation GO:0031638 18 12 0,000 0,04723126 0,07556383 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,04723126 0,07551438 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,04723126 0,07546499 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,04723126 0,07541567 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,04723126 0,07536641 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,04723126 0,07531721 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,04723126 0,07526808 ! defense response to fungus GO:0050832 15 12 0,000 0,04723126 0,07521901 ! lamellipodium assembly GO:0030032 24 12 0,000 0,04723126 0,07517001 ! response to cold GO:0009409 17 12 0,000 0,04723126 0,07512107 ! establishment of cell polarity GO:0030010 21 12 0,000 0,04723126 0,0750722 ! regulation of synapse organization GO:0050807 18 12 0,000 0,04723126 0,07502339 ! localization within membrane GO:0051668 26 12 0,000 0,04723126 0,07497464 ! regulation of protein transport GO:0051223 165 87 1,000 0,04815379 0,07638941 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,04914686 0,07791419 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05106572 0,08090373 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05106572 0,08085129 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05106572 0,08079893 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05106572 0,08074663 ! peroxisomal transport GO:0043574 28 13 0,000 0,05106572 0,0806944 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05106572 0,08064224 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05106572 0,08059015 ! organelle fusion GO:0048284 36 13 0,000 0,05106572 0,08053812 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05106572 0,08048616 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05106572 0,08043427 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05106572 0,08038244 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05106572 0,08033068 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05106572 0,08027899 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05106572 0,08022736 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05106572 0,0801758 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05106572 0,08012431 ! methionine metabolic process GO:0006555 31 13 0,000 0,05106572 0,08007288 ! plasma membrane organization GO:0007009 27 13 0,000 0,05106572 0,08002152 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05106572 0,07997022 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05106572 0,07991899 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05106572 0,07986783 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05106572 0,07981673 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,05106572 0,07976569 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05106572 0,07971473 ! exocrine system development GO:0035272 34 13 0,000 0,05106572 0,07966382 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05106572 0,07961298 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05106572 0,07956221 ! L-glutamate transport GO:0015813 30 13 0,000 0,05106572 0,0795115 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05106572 0,07946086 ! protein homotetramerization GO:0051289 24 13 0,000 0,05106572 0,07941028 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05106572 0,07935976 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05106572 0,07930931 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05106572 0,07925892 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05106572 0,0792086 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05106572 0,07915834 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05106572 0,07910815 ! histone methylation GO:0016571 29 13 0,000 0,05106572 0,07905801 ! chromatin silencing GO:0006342 29 13 0,000 0,05106572 0,07900795 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05106572 0,07895794 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05106572 0,078908 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05106572 0,07885812 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05106572 0,0788083 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05106572 0,07875855 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05106572 0,07870886 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05106572 0,07865923 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05106572 0,07860967 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05106572 0,07856017 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05106572 0,07851073 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05106572 0,07846135 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05106572 0,07841203 ! insulin secretion GO:0030073 24 13 0,000 0,05106572 0,07836278 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05106572 0,07831359 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05106572 0,07826446 ! acrosome reaction GO:0007340 19 13 0,000 0,05106572 0,07821539 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05106572 0,07816638 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05106572 0,07811744 ! response to inorganic substance GO:0010035 173 90 1,000 0,05115519 0,07820533 ! ossification GO:0001503 205 91 1,000 0,05217029 0,07970733 ! defense response to bacterium GO:0042742 112 91 1,000 0,05217029 0,07965752 ! bone development GO:0060348 206 92 1,000 0,0531926 0,08116772 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,05422203 0,0826869 ! rRNA transcription GO:0009303 28 14 0,000 0,05488485 0,08364547 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05488485 0,08359332 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05488485 0,08354124 ! water transport GO:0006833 21 14 0,000 0,05488485 0,08348922 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05488485 0,08343727 ! non-recombinational repair GO:0000726 29 14 0,000 0,05488485 0,08338538 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05488485 0,08333355 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05488485 0,08328179 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05488485 0,0832301 ! lipid localization GO:0010876 32 14 0,000 0,05488485 0,08317847 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05488485 0,0831269 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,05488485 0,0830754 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05488485 0,08302396 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05488485 0,08297258 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05488485 0,08292127 ! arginine metabolic process GO:0006525 21 14 0,000 0,05488485 0,08287002 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05488485 0,08281883 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05488485 0,08276771 ! regulation of heart rate GO:0002027 25 14 0,000 0,05488485 0,08271665 ! organic alcohol transport GO:0015850 29 14 0,000 0,05488485 0,08266565 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05488485 0,08261472 ! embryo implantation GO:0007566 30 14 0,000 0,05488485 0,08256385 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05488485 0,08251304 ! bone mineralization GO:0030282 18 14 0,000 0,05488485 0,08246229 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05488485 0,08241161 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05488485 0,08236099 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05488485 0,08231043 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05488485 0,08225993 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05488485 0,0822095 ! ribosome assembly GO:0042255 18 14 0,000 0,05488485 0,08215912 ! cerebellum development GO:0021549 23 14 0,000 0,05488485 0,08210881 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05488485 0,08205856 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05488485 0,08200837 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05488485 0,08195824 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05488485 0,08190818 ! NADP metabolic process GO:0006739 24 14 0,000 0,05488485 0,08185817 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05488485 0,08180823 ! oxygen transport GO:0015671 22 14 0,000 0,05488485 0,08175835 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05488485 0,08170852 ! male genitalia development GO:0030539 26 14 0,000 0,05488485 0,08165876 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05488485 0,08160906 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05488485 0,08155942 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,0552585 0,08206476 ! female pregnancy GO:0007565 166 94 1,000 0,0552585 0,0820149 ! regulation of membrane potential GO:0042391 179 94 1,000 0,0552585 0,0819651 ! phospholipid biosynthetic process GO:0008654 188 95 1,000 0,05630196 0,08346219 ! sex differentiation GO:0007548 171 96 1,000 0,05735232 0,08496769 ! response to protein stimulus GO:0051789 158 96 1,000 0,05735232 0,0849162 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,05840952 0,08642911 ! lactation GO:0007595 30 15 0,000 0,05868872 0,08678967 ! reproductive cellular process GO:0048610 22 15 0,000 0,05868872 0,08673717 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05868872 0,08668473 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05868872 0,08663235 ! superoxide anion generation GO:0042554 22 15 0,000 0,05868872 0,08658004 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05868872 0,08652778 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05868872 0,0864756 ! copper ion transport GO:0006825 22 15 0,000 0,05868872 0,08642347 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05868872 0,08637141 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05868872 0,08631941 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05868872 0,08626747 ! sulfate transport GO:0008272 27 15 0,000 0,05868872 0,0862156 ! response to cAMP GO:0051591 25 15 0,000 0,05868872 0,08616379 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05868872 0,08611204 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05868872 0,08606035 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,05868872 0,08600872 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05868872 0,08595716 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05868872 0,08590566 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,05868872 0,08585422 ! vesicle coating GO:0006901 38 15 0,000 0,05868872 0,08580284 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05868872 0,08575152 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05868872 0,08570026 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05868872 0,08564907 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05868872 0,08559793 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05868872 0,08554686 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05868872 0,08549585 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05868872 0,0854449 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05868872 0,08539401 ! histone deacetylation GO:0016575 24 15 0,000 0,05868872 0,08534318 ! water homeostasis GO:0030104 28 15 0,000 0,05868872 0,08529241 ! cofactor transport GO:0051181 30 15 0,000 0,05868872 0,0852417 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05868872 0,08519105 ! intestinal absorption GO:0050892 31 15 0,000 0,05868872 0,08514046 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05868872 0,08508993 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05868872 0,08503947 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05868872 0,08498906 ! cell killing GO:0001906 32 15 0,000 0,05868872 0,08493871 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05868872 0,08488842 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05868872 0,08483819 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05868872 0,08478802 ! actin filament polymerization GO:0030041 27 15 0,000 0,05868872 0,08473791 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05868872 0,08468786 ! forebrain development GO:0030900 210 98 1,000 0,05947348 0,08576961 ! mRNA transport GO:0051028 185 100 1,000 0,06162141 0,08881481 ! positive regulation of immune response GO:0050778 175 100 1,000 0,06162141 0,08876244 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06247738 0,0899424 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06247738 0,08988943 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06247738 0,08983652 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06247738 0,08978368 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06247738 0,08973089 ! bone remodeling GO:0046849 28 16 0,000 0,06247738 0,08967817 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06247738 0,08962551 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06247738 0,08957292 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06247738 0,08952038 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06247738 0,08946791 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06247738 0,0894155 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06247738 0,08936314 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06247738 0,08931085 ! startle response GO:0001964 28 16 0,000 0,06247738 0,08925863 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06247738 0,08920646 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06247738 0,08915435 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06247738 0,08910231 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06247738 0,08905032 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06247738 0,0889984 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06247738 0,08894653 ! pituitary gland development GO:0021983 30 16 0,000 0,06247738 0,08889473 ! response to osmotic stress GO:0006970 27 16 0,000 0,06247738 0,08884299 ! lysosomal transport GO:0007041 31 16 0,000 0,06247738 0,0887913 ! fructose metabolic process GO:0006000 25 16 0,000 0,06247738 0,08873968 ! L-amino acid transport GO:0015807 33 16 0,000 0,06247738 0,08868812 ! stem cell development GO:0048864 46 16 0,000 0,06247738 0,08863661 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06247738 0,08858517 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06247738 0,08853379 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06247738 0,08848246 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06247738 0,0884312 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06247738 0,08837999 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06247738 0,08832885 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06247738 0,08827776 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06247738 0,08822673 ! tissue regeneration GO:0042246 27 16 0,000 0,06247738 0,08817577 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06247738 0,08812486 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06247738 0,08807401 ! biomineral formation GO:0031214 22 16 0,000 0,06247738 0,08802321 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06247738 0,08797248 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06247738 0,0879218 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06247738 0,08787119 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06247738 0,08782063 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06247738 0,08777013 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06247738 0,08771968 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06247738 0,0876693 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,06247738 0,08761897 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,06247738 0,0875687 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06625091 0,09280445 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,06625091 0,09275127 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,06625091 0,09269815 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,06625091 0,09264509 ! signal complex assembly GO:0007172 47 17 0,000 0,06625091 0,09259209 ! filopodium assembly GO:0046847 42 17 0,000 0,06625091 0,09253915 ! endothelial cell migration GO:0043542 31 17 0,000 0,06625091 0,09248627 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06625091 0,09243345 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06625091 0,09238069 ! glial cell development GO:0021782 28 17 0,000 0,06625091 0,09232799 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,06625091 0,09227535 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06625091 0,09222277 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06625091 0,09217026 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06625091 0,0921178 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06625091 0,0920654 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,06625091 0,09201306 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,06625091 0,09196078 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,06625091 0,09190856 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06625091 0,09185639 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06625091 0,09180429 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,06625091 0,09175225 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,06625091 0,09170027 ! membrane budding GO:0006900 42 17 0,000 0,06625091 0,09164834 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06625091 0,09159647 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06625091 0,09154467 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06625091 0,09149292 ! genitalia development GO:0048806 32 17 0,000 0,06625091 0,09144122 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06625091 0,09138959 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,06625091 0,09133802 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06625091 0,0912865 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06625091 0,09123504 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,06625091 0,09118364 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06625091 0,0911323 ! steroid catabolic process GO:0006706 34 17 0,000 0,06625091 0,09108102 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06625091 0,09102979 ! gas transport GO:0015669 26 17 0,000 0,06625091 0,09097862 ! organic cation transport GO:0015695 32 17 0,000 0,06625091 0,09092751 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06625091 0,09087646 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06625091 0,09082546 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07000935 0,09592419 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07000935 0,09587043 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07000935 0,09581672 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07000935 0,09576307 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07000935 0,09570948 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07000935 0,09565595 ! centrosome cycle GO:0007098 26 18 0,000 0,07000935 0,09560248 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07000935 0,09554907 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07000935 0,09549572 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07000935 0,09544243 ! response to retinoic acid GO:0032526 31 18 0,000 0,07000935 0,0953892 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,07000935 0,09533603 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07000935 0,09528292 ! DNA integration GO:0015074 32 18 0,000 0,07000935 0,09522987 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07000935 0,09517687 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07000935 0,09512394 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07000935 0,09507106 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07000935 0,09501824 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07000935 0,09496548 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,07000935 0,09491278 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07000935 0,09486014 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,07000935 0,09480756 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,07000935 0,09475504 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07000935 0,09470257 ! nerve development GO:0021675 34 18 0,000 0,07000935 0,09465016 ! microspike assembly GO:0030035 46 18 0,000 0,07000935 0,09459781 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07000935 0,09454552 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,07000935 0,09449328 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07375277 0,09949089 ! positive regulation of translation GO:0045727 31 19 0,000 0,07375277 0,09943599 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07375277 0,09938114 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,07375277 0,09932636 ! neuron maturation GO:0042551 46 19 0,000 0,07375277 0,09927163 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07375277 0,09921696 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07375277 0,09916236 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07375277 0,09910782 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,07375277 0,09905333 ! inositol metabolic process GO:0006020 33 19 0,000 0,07375277 0,09899891 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07375277 0,09894454 ! memory GO:0007613 34 19 0,000 0,07375277 0,09889024 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,07375277 0,09883599 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07375277 0,0987818 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07375277 0,09872768 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07375277 0,09867361 ! cerebral cortex development GO:0021987 40 19 0,000 0,07375277 0,0986196 ! response to vitamin A GO:0033189 32 19 0,000 0,07375277 0,09856565 ! heme metabolic process GO:0042168 40 19 0,000 0,07375277 0,09851176 ! neuromuscular junction development GO:0007528 43 19 0,000 0,07375277 0,09845793 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07375277 0,09840416 ! response to fungus GO:0009620 26 19 0,000 0,07375277 0,09835044 ! peptide cross-linking GO:0018149 39 19 0,000 0,07375277 0,09829679 ! protein export from nucleus GO:0006611 40 19 0,000 0,07375277 0,09824319 ! heart process GO:0003015 32 19 0,000 0,07375277 0,09818965 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07375277 0,09813617 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07375277 0,09808275 ! visual learning GO:0008542 38 19 0,000 0,07375277 0,09802938 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07375277 0,09797608 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07375277 0,09792283 ! vitamin transport GO:0051180 31 19 0,000 0,07375277 0,09786964 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07375277 0,09781651 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07375277 0,09776343 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07375277 0,09771042 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,07375277 0,09765746 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,07375277 0,09760455 ! cilium assembly GO:0042384 38 19 0,000 0,07375277 0,09755171 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07375277 0,09749892 ! protein secretion GO:0009306 45 20 0,000 0,07748122 0,10237243 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,07748122 0,10231709 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,07748122 0,10226182 ! positive regulation of ossification GO:0045778 50 20 0,000 0,07748122 0,1022066 ! skin development GO:0043588 42 20 0,000 0,07748122 0,10215144 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,07748122 0,10209634 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,07748122 0,10204131 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,07748122 0,10198633 ! response to vitamin GO:0033273 36 20 0,000 0,07748122 0,10193141 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,07748122 0,10187655 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,07748122 0,10182174 ! bile acid metabolic process GO:0008206 34 20 0,000 0,07748122 0,101767 ! retinoid metabolic process GO:0001523 34 20 0,000 0,07748122 0,10171232 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,07748122 0,10165769 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,07748122 0,10160313 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,07748122 0,10154862 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,07748122 0,10149417 ! body fluid secretion GO:0007589 33 20 0,000 0,07748122 0,10143978 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,07748122 0,10138544 ! peptide secretion GO:0002790 38 20 0,000 0,07748122 0,10133117 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,07748122 0,10127695 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,07748122 0,10122279 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,07748122 0,10116869 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,07748122 0,10111465 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,07748122 0,10106066 ! cell-cell junction organization GO:0045216 43 20 0,000 0,07748122 0,10100674 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,07748122 0,10095287 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,07748122 0,10089905 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,07748122 0,1008453 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,07748122 0,1007916 ! regulation of glucose import GO:0046324 30 20 0,000 0,07748122 0,10073796 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,07748122 0,10068437 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,07748122 0,10063085 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,07748122 0,10057738 ! negative regulation of translation GO:0017148 32 20 0,000 0,07748122 0,10052396 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,07748122 0,10047061 ! regulation of cell killing GO:0031341 46 21 0,000 0,08119477 0,10523015 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08119477 0,10517435 ! hormone secretion GO:0046879 39 21 0,000 0,08119477 0,10511862 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08119477 0,10506294 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08119477 0,10500732 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08119477 0,10495176 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08119477 0,10489626 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08119477 0,10484082 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,08119477 0,10478543 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,08119477 0,10473011 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08119477 0,10467484 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08119477 0,10461964 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08119477 0,10456449 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08119477 0,10450939 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08119477 0,10445436 ! sensory perception of pain GO:0019233 33 21 0,000 0,08119477 0,10439938 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08119477 0,10434447 ! diencephalon development GO:0021536 36 21 0,000 0,08119477 0,1042896 ! collagen fibril organization GO:0030199 62 21 0,000 0,08119477 0,1042348 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,08119477 0,10418006 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08119477 0,10412537 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08119477 0,10407074 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08119477 0,10401617 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08119477 0,10396165 ! collagen catabolic process GO:0030574 29 21 0,000 0,08119477 0,10390719 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08119477 0,10385279 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08119477 0,10379844 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08119477 0,10374416 ! actin filament-based movement GO:0030048 47 21 0,000 0,08119477 0,10368993 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,08489348 0,10835672 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,08489348 0,10830014 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,08489348 0,10824362 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,08489348 0,10818715 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,08489348 0,10813074 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,08489348 0,1080744 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,08489348 0,10801811 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,08489348 0,10796188 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,08489348 0,10790571 ! vacuolar transport GO:0007034 41 22 0,000 0,08489348 0,10784959 ! central nervous system neuron development GO:0021954 47 22 0,000 0,08489348 0,10779354 ! fucose metabolic process GO:0006004 44 22 0,000 0,08489348 0,10773754 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,08489348 0,1076816 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,08489348 0,10762572 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,08489348 0,1075699 ! stem cell differentiation GO:0048863 57 22 0,000 0,08489348 0,10751414 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,08489348 0,10745843 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,08489348 0,10740278 ! cytolysis GO:0019835 27 22 0,000 0,08489348 0,10734719 ! vasodilation GO:0042311 40 22 0,000 0,08489348 0,10729165 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,08489348 0,10723618 ! G1 phase GO:0051318 44 22 0,000 0,08489348 0,10718076 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,08489348 0,1071254 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,08489348 0,10707009 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,08489348 0,10701484 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,08489348 0,10695965 ! sarcomere organization GO:0045214 32 22 0,000 0,08489348 0,10690452 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,08489348 0,10684944 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,08489348 0,10679442 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,08489348 0,10673946 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,08489348 0,10668455 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,08489348 0,1066297 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,08489348 0,10657491 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,08489348 0,10652017 ! protein stabilization GO:0050821 41 22 0,000 0,08489348 0,10646549 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,0885774 0,11102852 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,0885774 0,11097158 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,0885774 0,1109147 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,0885774 0,11085788 ! gluconeogenesis GO:0006094 38 23 0,000 0,0885774 0,11080112 ! glycerol metabolic process GO:0006071 40 23 0,000 0,0885774 0,11074441 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,0885774 0,11068777 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,0885774 0,11063118 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,0885774 0,11057465 ! axis specification GO:0009798 43 23 0,000 0,0885774 0,11051817 ! visual behavior GO:0007632 46 23 0,000 0,0885774 0,11046176 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,0885774 0,1104054 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,0885774 0,1103491 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,0885774 0,11029286 ! peroxisome organization GO:0007031 43 23 0,000 0,0885774 0,11023667 ! lysosome organization GO:0007040 47 23 0,000 0,0885774 0,11018054 ! vesicle targeting GO:0006903 49 23 0,000 0,0885774 0,11012447 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,0885774 0,11006846 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,0885774 0,1100125 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,0885774 0,1099566 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,0885774 0,10990075 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,0885774 0,10984497 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,0885774 0,10978924 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,0885774 0,10973356 ! hormone transport GO:0009914 41 23 0,000 0,0885774 0,10967795 ! cell-cell recognition GO:0009988 28 23 0,000 0,0885774 0,10962238 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,0885774 0,10956688 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,0885774 0,10951143 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,0885774 0,10945604 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,09224659 0,11393247 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,09224659 0,1138749 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,09224659 0,11381739 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,09224659 0,11375993 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,09224659 0,11370254 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,09224659 0,1136452 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,09224659 0,11358792 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,09224659 0,11353069 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,09224659 0,11347353 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,09224659 0,11341642 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,09224659 0,11335937 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,09224659 0,11330238 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,09224659 0,11324544 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,09224659 0,11318856 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,09224659 0,11313174 ! sex determination GO:0007530 48 24 0,000 0,09224659 0,11307498 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,09224659 0,11301827 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,09224659 0,11296162 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,09224659 0,11290502 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,09224659 0,11284849 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,09224659 0,11279201 ! membrane depolarization GO:0051899 45 24 0,000 0,09224659 0,11273558 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,09224659 0,11267921 ! platelet activation GO:0030168 41 24 0,000 0,09224659 0,1126229 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,09224659 0,11256665 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,09224659 0,11251045 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,09224659 0,1124543 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,09224659 0,11239822 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,09224659 0,11234219 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,09224659 0,11228621 ! regulation of amine transport GO:0051952 41 24 0,000 0,09224659 0,11223029 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,09224659 0,11217443 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,09590112 0,11656041 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,09590112 0,11650245 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,09590112 0,11644455 ! leukocyte adhesion GO:0007159 55 25 0,000 0,09590112 0,1163867 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,09590112 0,11632891 ! phototransduction GO:0007602 37 25 0,000 0,09590112 0,11627118 ! keratinization GO:0031424 37 25 0,000 0,09590112 0,11621351 ! vacuole organization GO:0007033 49 25 0,000 0,09590112 0,11615589 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,09590112 0,11609833 ! chromosome condensation GO:0030261 48 25 0,000 0,09590112 0,11604083 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,09590112 0,11598338 ! interaction with host GO:0051701 66 25 0,000 0,09590112 0,11592599 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,09590112 0,11586866 ! immunoglobulin production GO:0002377 62 25 0,000 0,09590112 0,11581139 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,09590112 0,11575417 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,09590112 0,115697 ! liver development GO:0001889 55 25 0,000 0,09590112 0,1156399 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,09954103 0,11996978 ! myelination GO:0042552 50 26 0,000 0,09954103 0,11991062 ! initiation of viral infection GO:0019059 60 26 0,000 0,09954103 0,11985153 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,09954103 0,11979248 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,09954103 0,1197335 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,09954103 0,11967458 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,09954103 0,11961571 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,09954103 0,1195569 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,09954103 0,11949815 ! digestive system process GO:0022600 49 26 0,000 0,09954103 0,11943946 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,09954103 0,11938083 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,09954103 0,11932225 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,09954103 0,11926373 ! osteoblast differentiation GO:0001649 63 26 0,000 0,09954103 0,11920527 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,09954103 0,11914686 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,09954103 0,11908851 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,09954103 0,11903022 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,09954103 0,11897199 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,09954103 0,11891381 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,09954103 0,11885569 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,09954103 0,11879763 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,09954103 0,11873962 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,09954103 0,11868167 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,09954103 0,11862378 ! blastocyst development GO:0001824 50 26 0,000 0,09954103 0,11856594 ! telomere organization GO:0032200 46 26 0,000 0,09954103 0,11850816 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,09954103 0,11845044 ! neural tube closure GO:0001843 58 26 0,000 0,09954103 0,11839277 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,09954103 0,11833516 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,09954103 0,1182776 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,09954103 0,1182201 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1031664 0,12246623 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1031664 0,12240675 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1031664 0,12234733 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1031664 0,12228797 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1031664 0,12222866 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1031664 0,12216942 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1031664 0,12211023 ! tube lumen formation GO:0035148 59 27 0,000 0,1031664 0,12205109 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1031664 0,12199202 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1031664 0,121933 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,1031664 0,12187404 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1031664 0,12181513 ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,1031664 0,12175628 ! neuron fate commitment GO:0048663 52 28 0,000 0,10677726 0,12595696 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,10677726 0,12589617 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,10677726 0,12583543 ! vesicle docking GO:0048278 55 28 0,000 0,10677726 0,12577476 ! circadian rhythm GO:0007623 56 28 0,000 0,10677726 0,12571415 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,10677726 0,12565359 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,10677726 0,12559309 ! sperm motility GO:0030317 37 28 0,000 0,10677726 0,12553265 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,10677726 0,12547227 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,10677726 0,12541195 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,10677726 0,12535168 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,10677726 0,12529148 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,10677726 0,12523133 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,10677726 0,12517124 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,10677726 0,1251112 ! glutathione metabolic process GO:0006749 42 28 0,000 0,10677726 0,12505123 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,10677726 0,12499131 ! lipid oxidation GO:0034440 48 28 0,000 0,10677726 0,12493144 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,10677726 0,12487164 ! translational initiation GO:0006413 66 29 0,000 0,1103737 0,12901576 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,1103737 0,12895406 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,1103737 0,12889242 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,1103737 0,12883084 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,1103737 0,12876931 ! primary neural tube formation GO:0014020 61 29 0,000 0,1103737 0,12870785 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,1103737 0,12864644 ! synaptogenesis GO:0007416 46 29 0,000 0,1103737 0,12858509 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,1103737 0,1285238 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,1103737 0,12846257 ! phenol metabolic process GO:0018958 56 30 0,000 0,11395575 0,13256852 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,11395575 0,13250542 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,11395575 0,13244238 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,11395575 0,13237941 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,11395575 0,13231649 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,11395575 0,13225363 ! acute-phase response GO:0006953 50 30 0,000 0,11395575 0,13219083 ! myofibril assembly GO:0030239 50 30 0,000 0,11395575 0,13212809 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,11395575 0,13206541 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,11395575 0,13200279 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,11395575 0,13194023 ! cell fate determination GO:0001709 64 30 0,000 0,11395575 0,13187773 ! phospholipid transport GO:0015914 65 30 0,000 0,11395575 0,13181529 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,11395575 0,13175291 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,11395575 0,13169058 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,11395575 0,13162832 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,11395575 0,13156611 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 0,000 0,11395575 0,13150396 ! regulation of coagulation GO:0050818 52 30 0,000 0,11395575 0,13144187 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,11752348 0,13549309 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,11752348 0,13542918 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,11752348 0,13536532 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,11752348 0,13530153 ! regulation of innate immune response GO:0045088 57 31 0,000 0,11752348 0,1352378 ! peptide transport GO:0015833 60 31 0,000 0,11752348 0,13517413 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,11752348 0,13511052 ! detection of light stimulus GO:0009583 44 31 0,000 0,11752348 0,13504697 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,11752348 0,13498348 ! natural killer cell activation GO:0030101 50 31 0,000 0,11752348 0,13492004 ! ensheathment of neurons GO:0007272 64 31 0,000 0,11752348 0,13485667 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,11752348 0,13479336 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,11752348 0,1347301 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,11752348 0,13466691 ! eye morphogenesis GO:0048592 65 31 0,000 0,11752348 0,13460377 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,11752348 0,1345407 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,12107694 0,13854378 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,12107694 0,13847892 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,12107694 0,13841411 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,12107694 0,13834937 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,12107694 0,1382847 ! muscle cell development GO:0055001 52 32 0,000 0,12107694 0,13822008 ! mesoderm formation GO:0001707 73 32 0,000 0,12107694 0,13815552 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,12107694 0,13809102 ! peripheral nervous system development GO:0007422 68 32 0,000 0,12107694 0,13802658 ! BMP signaling pathway GO:0030509 71 32 0,000 0,12107694 0,1379622 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,12107694 0,13789788 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,12107694 0,13783363 ! gene silencing GO:0016458 71 32 0,000 0,12107694 0,13776943 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,12461619 0,14173061 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,12461619 0,14166466 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,12461619 0,14159877 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,12461619 0,14153294 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,12461619 0,14146718 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,12461619 0,14140147 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,12461619 0,14133582 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,12461619 0,14127024 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,12461619 0,14120471 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,12461619 0,14113925 ! glial cell differentiation GO:0010001 67 34 0,000 0,1281413 0,1450645 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,1281413 0,14499731 ! cholesterol transport GO:0030301 62 34 0,000 0,1281413 0,14493018 ! spliceosome assembly GO:0000245 75 34 0,000 0,1281413 0,14486311 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,1281413 0,14479611 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,1281413 0,14472917 ! formation of primary germ layer GO:0001704 76 34 0,000 0,1281413 0,14466228 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,1281413 0,14459547 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,1281413 0,14452871 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,1316523 0,1484202 ! negative regulation of secretion GO:0051048 68 35 0,000 0,1316523 0,14835174 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,1316523 0,14828334 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,1316523 0,14821501 ! membrane docking GO:0022406 69 35 0,000 0,1316523 0,14814674 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,1316523 0,14807853 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,1316523 0,14801039 ! ceramide metabolic process GO:0006672 72 35 0,000 0,1316523 0,1479423 ! sterol transport GO:0015918 63 35 0,000 0,1316523 0,14787428 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,1316523 0,14780633 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,1316523 0,14773843 ! vesicle localization GO:0051648 70 35 0,000 0,1316523 0,1476706 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,13514927 0,15152348 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,13514927 0,15145397 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,13514927 0,15138453 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,13514927 0,15131515 ! protein targeting to membrane GO:0006612 75 36 0,000 0,13514927 0,15124583 ! aerobic respiration GO:0009060 56 36 0,000 0,13514927 0,15117658 ! cytokine production GO:0001816 68 36 0,000 0,13514927 0,15110739 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,13514927 0,15103827 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,13514927 0,15096921 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,13863225 0,15478911 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,13863225 0,1547184 ! sister chromatid segregation GO:0000819 65 37 0,000 0,13863225 0,15464775 ! odontogenesis GO:0042476 74 37 0,000 0,13863225 0,15457717 ! actomyosin structure organization GO:0031032 68 37 0,000 0,13863225 0,15450665 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,13863225 0,15443619 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,13863225 0,1543658 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,13863225 0,15429548 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,13863225 0,15422522 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,1421013 0,1580125 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,1421013 0,15794061 ! meiosis I GO:0007127 74 38 0,000 0,1421013 0,15786879 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,1421013 0,15779703 ! organic anion transport GO:0015711 82 38 0,000 0,1421013 0,15772534 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,1421013 0,15765371 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,1421013 0,15758215 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,1421013 0,15751065 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,1421013 0,15743921 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,1421013 0,15736785 ! spermatid development GO:0007286 69 38 0,000 0,1421013 0,15729654 ! glycogen metabolic process GO:0005977 63 38 0,000 0,1421013 0,1572253 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,14555647 0,16097531 ! negative regulation of binding GO:0051100 71 39 0,000 0,14555647 0,16090247 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,14555647 0,1608297 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,14555647 0,16075699 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,14555647 0,16068435 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,14555647 0,16061177 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,14555647 0,16053926 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 0,000 0,14555647 0,16046682 GO:0006073|cellular glucan metabolic process, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,14899783 0,1641866 ! learning GO:0007612 82 40 0,000 0,14899783 0,16411258 ! nucleus organization GO:0006997 73 40 0,000 0,14899783 0,16403862 ! mismatch repair GO:0006298 58 40 0,000 0,14899783 0,16396473 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,14899783 0,16389091 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,14899783 0,16381715 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,14899783 0,16374346 ! RNA export from nucleus GO:0006405 61 41 0,000 0,15242543 0,16743494 ! mRNA catabolic process GO:0006402 79 41 0,000 0,15242543 0,16735969 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,15242543 0,16728451 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,15242543 0,16720939 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,15242543 0,16713434 ! gliogenesis GO:0042063 91 41 0,000 0,15242543 0,16705936 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,15242543 0,16698445 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,15242543 0,1669096 ! spermatid differentiation GO:0048515 73 41 0,000 0,15242543 0,16683482 ! RNA modification GO:0009451 64 41 0,000 0,15242543 0,16676011 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,15583931 0,17041873 ! ear morphogenesis GO:0042471 64 42 0,000 0,15583931 0,17034248 ! organic ether metabolic process GO:0018904 59 42 0,000 0,15583931 0,1702663 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,15583931 0,17019018 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,15583931 0,17011414 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,15583931 0,17003816 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,15583931 0,16996225 ! regulation of protein secretion GO:0050708 77 42 0,000 0,15583931 0,16988641 ! cytokinesis GO:0000910 84 42 0,000 0,15583931 0,16981063 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,15923954 0,17343834 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,15923954 0,17336105 ! regulation of tube size GO:0035150 76 43 0,000 0,15923954 0,17328383 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,15923954 0,17320668 ! glucose transport GO:0015758 66 43 0,000 0,15923954 0,17312959 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,15923954 0,17305258 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,15923954 0,17297563 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,15923954 0,17289876 ! ion transmembrane transport GO:0034220 79 43 0,000 0,15923954 0,17282195 ! neuron migration GO:0001764 85 43 0,000 0,15923954 0,1727452 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,16262617 0,17634076 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,16262617 0,17626253 ! hexose transport GO:0008645 68 44 0,000 0,16262617 0,17618436 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,16262617 0,17610627 ! striated muscle contraction GO:0006941 85 44 0,000 0,16262617 0,17602824 ! phagocytosis GO:0006909 105 44 0,000 0,16262617 0,17595028 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,16262617 0,17587239 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,16599925 0,17944079 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,16599925 0,17936142 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,16599925 0,17928213 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,16599925 0,17920291 ! polyol metabolic process GO:0019751 77 45 0,000 0,16599925 0,17912375 ! maintenance of location in cell GO:0051651 101 45 0,000 0,16599925 0,17904467 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,16935884 0,18258767 ! glycolysis GO:0006096 71 46 0,000 0,16935884 0,18250713 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,16935884 0,18242666 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,16935884 0,18234626 ! cell growth GO:0016049 90 46 0,000 0,16935884 0,18226593 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,172705 0,18578525 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,17603776 0,18928708 ! positive regulation of defense response GO:0031349 88 48 0,000 0,17603776 0,18920381 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,17603776 0,1891206 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,17603776 0,18903747 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,17603776 0,18895442 ! endosome transport GO:0016197 127 48 0,000 0,17603776 0,18887143 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,17603776 0,18878852 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,17603776 0,18870568 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,17603776 0,18862292 ! response to calcium ion GO:0051592 94 49 0,000 0,1793572 0,19209541 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,1793572 0,19201123 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,1793572 0,19192713 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,1793572 0,19184309 ! JNK cascade GO:0007254 106 49 0,000 0,1793572 0,19175914 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,1793572 0,19167525 ! regulation of action potential GO:0001508 102 50 0,000 0,18266335 0,19512311 ! regulation of ion transport GO:0043269 86 50 0,000 0,18266335 0,19503783 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,18266335 0,19495263 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,18266335 0,19486749 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,18595628 0,19829384 ! peptide metabolic process GO:0006518 80 51 0,000 0,18595628 0,19820732 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,18595628 0,19812088 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,18595628 0,19803452 ! Notch signaling pathway GO:0007219 111 52 0,000 0,18923603 0,20143948 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,18923603 0,20135175 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,18923603 0,20126409 ! excretion GO:0007588 87 52 0,000 0,18923603 0,20117651 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,18923603 0,201089 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,18923603 0,20100157 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,19250266 0,20438244 ! inner ear development GO:0048839 89 53 0,000 0,19250266 0,20429366 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,19250266 0,20420495 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,19250266 0,20411632 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! synapse organization GO:0050808 102 53 0,000 0,19250266 0,20402776 ! regulation of translational initiation GO:0006446 87 54 0,000 0,19575622 0,20738614 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,19575622 0,20729625 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 0,000 0,19575622 0,20720643 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,19575622 0,20711669 ! membrane fusion GO:0006944 122 54 0,000 0,19575622 0,20702703 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,19575622 0,20693745 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,19575622 0,20684794 ! RNA catabolic process GO:0006401 103 55 0,000 0,19899676 0,21018119 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,19899676 0,21009036 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,19899676 0,20999961 ! glucose catabolic process GO:0006007 88 56 0,000 0,20222434 0,2133135 ! RNA elongation GO:0006354 90 56 0,000 0,20222434 0,21322143 ! chloride transport GO:0006821 102 57 0,000 0,205439 0,21651746 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,205439 0,2164241 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,2086408 0,21970236 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,2086408 0,2196077 ! gastrulation GO:0007369 122 58 0,000 0,2086408 0,21951312 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,2086408 0,21941863 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,2086408 0,21932421 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,2086408 0,21922988 ! maintenance of location GO:0051235 124 58 0,000 0,2086408 0,21913563 ! nuclear export GO:0051168 110 59 0,000 0,21182978 0,22238941 ! establishment of organelle localization GO:0051656 122 59 0,000 0,21182978 0,22229389 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,21500601 0,22553013 ! DNA catabolic process GO:0006308 94 60 0,000 0,21500601 0,22543334 ! regulation of endocytosis GO:0030100 104 60 0,000 0,21500601 0,22533663 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,21500601 0,22524 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,21816952 0,22845613 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,21816952 0,22835825 ! regulation of heart contraction GO:0008016 123 61 0,000 0,21816952 0,22826045 ! camera-type eye development GO:0043010 126 61 0,000 0,21816952 0,22816273 ! proton transport GO:0015992 117 61 0,000 0,21816952 0,2280651 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,21816952 0,22796756 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,22132038 0,23116104 ! tRNA processing GO:0008033 102 62 0,000 0,22132038 0,23106226 ! regulation of mitosis GO:0007088 112 63 0,000 0,22445862 0,23423854 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,22445862 0,23413852 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,22445862 0,23403859 ! hydrogen transport GO:0006818 121 64 0,000 0,22758431 0,23719644 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,22758431 0,23709529 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,23069748 0,24023612 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,23069748 0,24013377 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,2337982 0,24325766 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,2337982 0,24315411 ! activation of MAPK activity GO:0000187 124 67 0,000 0,2368865 0,24626116 ! chromosome segregation GO:0007059 127 67 0,000 0,2368865 0,24615641 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,2368865 0,24605175 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,2368865 0,24594718 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,23996244 0,24903494 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,23996244 0,24892919 ! hexose catabolic process GO:0019320 113 68 0,000 0,23996244 0,24882354 ! extracellular matrix organization GO:0030198 146 68 0,000 0,23996244 0,24871797 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,23996244 0,24861249 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,23996244 0,2485071 ! regulation of lipase activity GO:0060191 137 68 0,000 0,23996244 0,2484018 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,23996244 0,24829659 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,24302608 0,25136016 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,24302608 0,25125379 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,24302608 0,2511475 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,24302608 0,25104131 ! single fertilization GO:0007338 83 69 0,000 0,24302608 0,25093521 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,24607744 0,25397854 ! cell redox homeostasis GO:0045454 114 70 0,000 0,24607744 0,25387128 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,2491166 0,2568982 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,2491166 0,25678981 ! carbohydrate transport GO:0008643 114 72 0,000 0,25214358 0,25980041 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,25214358 0,25969088 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,25214358 0,25958145 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,25214358 0,2594721 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,25214358 0,25936285 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,25214358 0,25925369 ! regulation of immune effector process GO:0002697 156 73 0,000 0,25515845 0,26224321 ! amino acid transport GO:0006865 148 74 0,000 0,25816125 0,26521781 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,25816125 0,26510632 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,25816125 0,26499493 ! organelle localization GO:0051640 155 74 0,000 0,25816125 0,26488364 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,26115203 0,26783981 ! eye development GO:0001654 155 75 0,000 0,26115203 0,26772741 ! learning or memory GO:0007611 161 76 0,000 0,26413084 0,27066763 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,26413084 0,27055415 ! neurotransmitter transport GO:0006836 142 77 0,000 0,26709772 0,27347851 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,26709772 0,27336394 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,26709772 0,27324947 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,26709772 0,27313509 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,26709772 0,27302081 ! fertilization GO:0009566 99 78 0,000 0,27005272 0,27592589 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,27005272 0,27581053 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,27299589 0,27869994 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,27299589 0,27858353 ! meiosis GO:0007126 143 81 0,000 0,27884692 0,2844355 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,27884692 0,28431679 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,27884692 0,28419818 ! meiotic cell cycle GO:0051321 144 82 0,000 0,28175488 0,28704219 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,28465119 0,28987197 ! exocytosis GO:0006887 153 83 0,000 0,28465119 0,28975119 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,28465119 0,28963051 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,28465119 0,28950994 GO:0045937|positive regulation of phosphate metabolic process, ! inorganic anion transport GO:0015698 156 83 0,000 0,28465119 0,28938946 ! digestion GO:0007586 130 84 0,000 0,28753591 0,29220059 ! regulation of ligase activity GO:0051340 147 84 0,000 0,28753591 0,2920791 ! negative regulation of transport GO:0051051 164 85 0,000 0,29040907 0,29487505 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,29040907 0,29475254 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,29040907 0,29463013 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,29040907 0,29450783 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,29327073 0,29728647 ! regulation of lyase activity GO:0051339 169 86 0,000 0,29327073 0,29716317 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,29327073 0,29703996 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,29612093 0,2998025 ! alcohol catabolic process GO:0046164 142 87 0,000 0,29612093 0,2996783 ! nucleosome assembly GO:0006334 126 87 0,000 0,29612093 0,29955421 ! cellular respiration GO:0045333 143 88 0,000 0,29895971 0,30230073 ! amine biosynthetic process GO:0009309 146 88 0,000 0,29895971 0,30217566 ! sensory perception of smell GO:0007608 117 88 0,000 0,29895971 0,30205069 ! chromatin assembly GO:0031497 128 88 0,000 0,29895971 0,30192582 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,30178712 0,30465535 ! cellular defense response GO:0006968 123 89 0,000 0,30178712 0,30452951 ! regulation of neurological system process GO:0031644 175 89 0,000 0,30178712 0,30440377 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,30460321 0,30711748 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,30460321 0,30699078 ! response to unfolded protein GO:0006986 139 90 0,000 0,30460321 0,30686418 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,30460321 0,30673769 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,30740802 0,30943461 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,3102016 0,312118 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,31298398 0,31478793 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,31298398 0,31465838 ! vitamin metabolic process GO:0006766 153 93 0,000 0,31298398 0,31452895 ! sterol metabolic process GO:0016125 166 94 0,000 0,31575523 0,31718339 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,31575523 0,31705303 ! regulation of defense response GO:0031347 171 95 0,000 0,31851537 0,31969311 ! nucleosome organization GO:0034728 143 95 0,000 0,31851537 0,31956182 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,31851537 0,31943064 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,31851537 0,31929957 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,31851537 0,3191686 ! regulation of T cell activation GO:0050863 175 96 0,000 0,32126445 0,32179133 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,32400252 0,32440089 ! transcription initiation GO:0006352 171 97 0,000 0,32400252 0,32426799 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,32672963 0,32686342 ! hormone metabolic process GO:0042445 171 100 0,000 0,3321511 0,3321511