pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1202-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 115 46 9,000 9,076E-13 2,184E-09 ! interphase of mitotic cell cycle GO:0051329 209 95 10,000 8,773E-11 1,055E-07 ! interphase GO:0051325 213 98 10,000 1,236E-10 9,909E-08 ! positive regulation of cell migration GO:0030335 126 57 8,000 2,722E-10 1,637E-07 ! response to hypoxia GO:0001666 171 81 9,000 3,366E-10 1,62E-07 ! response to oxygen levels GO:0070482 176 83 9,000 4,305E-10 1,726E-07 ! positive regulation of cell motion GO:0051272 146 64 8,000 7,98E-10 2,743E-07 ! apoptotic mitochondrial changes GO:0008637 41 20 5,000 4,401E-09 1,324E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 7,000 7,245E-09 1,937E-06 ! positive regulation of cell cycle GO:0045787 89 48 6,000 4,921E-08 1,184E-05 ! response to UV GO:0009411 104 53 6,000 9,996E-08 2,186E-05 ! peptidyl-serine phosphorylation GO:0018105 38 18 4,000 1,406E-07 2,819E-05 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 3,000 1,729E-07 3,2E-05 ! peptidyl-serine modification GO:0018209 43 20 4,000 2,514E-07 4,321E-05 ! nucleus organization GO:0006997 67 38 5,000 2,816E-07 4,517E-05 ! positive regulation of glucose metabolic process GO:0010907 18 9 3,000 3,094E-07 4,653E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 3,000 3,094E-07 4,379E-05 ! positive regulation of MAP kinase activity GO:0043406 160 93 7,000 3,583E-07 4,79E-05 ! apoptotic nuclear changes GO:0030262 32 22 4,000 4,222E-07 5,346E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 3,000 5,128E-07 6,17E-05 ! regulation of smooth muscle cell migration GO:0014910 27 10 3,000 5,128E-07 5,876E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 5,182E-07 5,668E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 5,742E-07 6,007E-05 ! negative regulation of cell size GO:0045792 134 69 6,000 6,352E-07 6,368E-05 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 3,000 8,014E-07 7,713E-05 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 3,000 8,014E-07 7,416E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 8,517E-07 7,59E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 1,03E-06 8,853E-05 ! positive regulation of cellular catabolic process GO:0031331 31 12 3,000 1,195E-06 9,917E-05 ! regulation of B cell proliferation GO:0030888 20 12 3,000 1,195E-06 9,587E-05 ! T cell homeostasis GO:0043029 25 12 3,000 1,195E-06 9,277E-05 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 3,000 1,717E-06 1,291E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 3,000 1,717E-06 1,252E-04 ! positive regulation of growth GO:0045927 90 52 5,000 1,911E-06 1,352E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 2,39E-06 1,643E-04 ! negative regulation of growth GO:0045926 155 84 6,000 2,436E-06 1,628E-04 ! mitochondrion organization GO:0007005 148 86 6,000 2,855E-06 1,857E-04 ! lymphocyte homeostasis GO:0002260 30 15 3,000 3,241E-06 2,052E-04 ! B cell homeostasis GO:0001782 13 5 2,000 3,55E-06 2,19E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 3,55E-06 2,135E-04 ! hemoglobin biosynthetic process GO:0042541 7 5 2,000 3,55E-06 2,083E-04 ! positive regulation of glycolysis GO:0045821 14 5 2,000 3,55E-06 2,034E-04 ! peptidyl-threonine phosphorylation GO:0018107 20 5 2,000 3,55E-06 1,986E-04 ! regulation of glucose metabolic process GO:0010906 28 16 3,000 4,298E-06 2,35E-04 ! response to peptide hormone stimulus GO:0043434 122 61 5,000 4,94E-06 2,641E-04 ! androgen receptor signaling pathway GO:0030521 74 36 4,000 5,571E-06 2,914E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 5,588E-06 2,861E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 5,588E-06 2,801E-04 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 3,000 5,588E-06 2,744E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 6,405E-06 3,082E-04 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 2,000 7,063E-06 3,332E-04 ! negative regulation of B cell activation GO:0050869 13 6 2,000 7,063E-06 3,268E-04 ! neuron maturation GO:0042551 42 18 3,000 7,145E-06 3,244E-04 ! negative regulation of cell growth GO:0030308 132 67 5,000 8,569E-06 3,818E-04 ! homeostasis of number of cells GO:0048872 114 67 5,000 8,569E-06 3,748E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 8,569E-06 3,681E-04 ! mesenchymal cell development GO:0014031 87 40 4,000 9,501E-06 4,011E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! urogenital system development GO:0001655 137 69 5,000 1,017E-05 4,219E-04 ! regulation of carbohydrate metabolic process GO:0006109 38 20 3,000 1,119E-05 4,562E-04 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 1,119E-05 4,486E-04 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 1,229E-05 4,849E-04 ! positive regulation of monooxygenase activity GO:0032770 12 7 2,000 1,229E-05 4,771E-04 ! oxygen homeostasis GO:0032364 12 7 2,000 1,229E-05 4,695E-04 ! peptidyl-threonine modification GO:0018210 25 7 2,000 1,229E-05 4,622E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 1,366E-05 5,056E-04 ! cell structure disassembly during apoptosis GO:0006921 30 21 3,000 1,374E-05 5,009E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 1,374E-05 4,935E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to cytokine stimulus GO:0034097 63 21 3,000 1,374E-05 4,862E-04 ! gut development GO:0048565 39 21 3,000 1,374E-05 4,792E-04 ! regulation of chemotaxis GO:0050920 40 22 3,000 1,67E-05 5,741E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 1,714E-05 5,807E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 1,912E-05 6,388E-04 ! hemoglobin metabolic process GO:0020027 13 8 2,000 1,957E-05 6,449E-04 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 1,957E-05 6,362E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,957E-05 6,277E-04 ! activation of pro-apoptotic gene products GO:0008633 47 23 3,000 2,01E-05 6,365E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 5,000 2,223E-05 6,946E-04 ! positive regulation of fibroblast proliferation GO:0048146 43 24 3,000 2,399E-05 7,4E-04 ! regulation of cellular catabolic process GO:0031329 52 24 3,000 2,399E-05 7,307E-04 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 3,000 2,399E-05 7,215E-04 ! regulation of behavior GO:0050795 43 24 3,000 2,399E-05 7,126E-04 ! regulation of oxidoreductase activity GO:0051341 46 24 3,000 2,399E-05 7,039E-04 ! leukocyte homeostasis GO:0001776 44 24 3,000 2,399E-05 6,954E-04 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 2,751E-05 7,879E-04 ! regulation of developmental growth GO:0048638 15 9 2,000 2,92E-05 8,264E-04 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 2,000 2,92E-05 8,168E-04 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 21 9 2,000 2,92E-05 8,074E-04 ! gas homeostasis GO:0033483 16 9 2,000 2,92E-05 7,983E-04 ! regulation of ligase activity GO:0051340 142 84 5,000 3,156E-05 8,531E-04 ! regulation of endothelial cell proliferation GO:0001936 57 26 3,000 3,338E-05 8,923E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 3,338E-05 8,825E-04 ! positive regulation of nuclear division GO:0051785 40 26 3,000 3,338E-05 8,729E-04 GO:0045840|positive regulation of mitosis, ! tube morphogenesis GO:0035239 176 86 5,000 3,607E-05 9,332E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 3,896E-05 9,973E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 3,896E-05 9,868E-04 ! regulation of chromosome organization GO:0033044 42 27 3,000 3,896E-05 9,765E-04 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 2,000 4,149E-05 1,029E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 4,149E-05 1,019E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 4,149E-05 1,008E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 4,149E-05 9,982E-04 ! regulation of cell adhesion GO:0030155 212 89 5,000 4,38E-05 1,043E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 4,52E-05 1,066E-03 ! positive regulation of organelle organization GO:0010638 100 56 4,000 5,027E-05 1,174E-03 ! cellular iron ion homeostasis GO:0006879 51 29 3,000 5,214E-05 1,206E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 5,675E-05 1,3E-03 ! regulation of leukocyte migration GO:0002685 26 11 2,000 5,675E-05 1,288E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 3,000 5,983E-05 1,345E-03 ! regulation of B cell activation GO:0050864 50 30 3,000 5,983E-05 1,333E-03 ! iron ion homeostasis GO:0055072 54 31 3,000 6,831E-05 1,508E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 7,024E-05 1,536E-03 ! kidney development GO:0001822 122 60 4,000 7,024E-05 1,522E-03 ! focal adhesion formation GO:0048041 35 12 2,000 7,527E-05 1,617E-03 ! histone acetylation GO:0016573 26 12 2,000 7,527E-05 1,603E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 7,527E-05 1,589E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 7,527E-05 1,575E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 2,000 7,527E-05 1,561E-03 ! metanephros development GO:0001656 74 32 3,000 7,764E-05 1,597E-03 ! positive regulation of catabolic process GO:0009896 64 32 3,000 7,764E-05 1,583E-03 ! regulation of homeostatic process GO:0032844 134 62 4,000 8,226E-05 1,663E-03 ! cell cycle arrest GO:0007050 213 100 5,000 8,419E-05 1,688E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 4,000 8,884E-05 1,766E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 2,000 9,733E-05 1,919E-03 ! plasma membrane organization GO:0007009 24 13 2,000 9,733E-05 1,904E-03 ! regulation of striated muscle tissue development GO:0016202 69 34 3,000 9,901E-05 1,921E-03 ! developmental maturation GO:0021700 116 66 4,000 1,11E-04 2,137E-03 ! regulation of muscle development GO:0048634 70 35 3,000 1,112E-04 2,123E-03 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 1,112E-04 2,106E-03 ! activation of MAPK activity GO:0000187 115 67 4,000 1,193E-04 2,242E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 1,232E-04 2,298E-03 ! negative regulation of cell activation GO:0050866 65 36 3,000 1,244E-04 2,302E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 1,28E-04 2,351E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 4,000 1,372E-04 2,501E-03 ! regulation of protein stability GO:0031647 73 37 3,000 1,387E-04 2,508E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 2,000 1,532E-04 2,751E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 1,532E-04 2,731E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 2,000 1,532E-04 2,711E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,532E-04 2,691E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 1,541E-04 2,687E-03 GO:0042593|glucose homeostasis, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 4,000 1,679E-04 2,906E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 4,000 1,679E-04 2,885E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 2,000 1,876E-04 3,201E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 1,876E-04 3,178E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,876E-04 3,156E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of viral genome replication GO:0045069 28 17 2,000 2,266E-04 3,786E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 2,266E-04 3,76E-03 ! neural crest cell migration GO:0001755 37 17 2,000 2,266E-04 3,734E-03 ! negative regulation of blood coagulation GO:0030195 24 17 2,000 2,266E-04 3,709E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 2,266E-04 3,684E-03 ! positive regulation of ligase activity GO:0051351 124 77 4,000 2,303E-04 3,719E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 2,597E-04 4,166E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 2,705E-04 4,31E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 2,705E-04 4,281E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 2,919E-04 4,59E-03 GO:0045937|positive regulation of phosphate metabolic process, ! branching morphogenesis of a tube GO:0048754 97 45 3,000 2,992E-04 4,674E-03 ! regulation of endothelial cell migration GO:0010594 44 19 2,000 3,195E-04 4,959E-03 ! G1 phase GO:0051318 40 19 2,000 3,195E-04 4,928E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 3,195E-04 4,896E-03 ! negative regulation of cell migration GO:0030336 115 46 3,000 3,258E-04 4,962E-03 ! pigmentation GO:0043473 100 46 3,000 3,258E-04 4,931E-03 ! protein amino acid acetylation GO:0006473 39 20 2,000 3,739E-04 5,623E-03 ! response to alkaloid GO:0043279 38 20 2,000 3,739E-04 5,588E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 3,739E-04 5,553E-03 ! negative regulation of translation GO:0017148 29 20 2,000 3,739E-04 5,519E-03 ! negative regulation of coagulation GO:0050819 29 20 2,000 3,739E-04 5,485E-03 ! cellular component disassembly GO:0022411 86 48 3,000 3,842E-04 5,603E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 3,842E-04 5,569E-03 ! regulation of cell cycle process GO:0010564 149 90 4,000 4,754E-04 6,849E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 4,853E-04 6,95E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 3,000 4,853E-04 6,909E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,998E-04 7,074E-03 ! ureteric bud development GO:0001657 43 22 2,000 4,998E-04 7,032E-03 ! renal system process GO:0003014 41 22 2,000 4,998E-04 6,992E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 4,998E-04 6,951E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 5,001E-04 6,916E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 1,000 5,001E-04 6,876E-03 ! response to food GO:0032094 6 5 1,000 5,001E-04 6,837E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 5,001E-04 6,798E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 5,001E-04 6,76E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 5,001E-04 6,723E-03 ! enteric nervous system development GO:0048484 8 5 1,000 5,001E-04 6,685E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 5,001E-04 6,648E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 5,001E-04 6,612E-03 ! stem cell division GO:0017145 11 5 1,000 5,001E-04 6,576E-03 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 5,001E-04 6,54E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,001E-04 6,504E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 5,001E-04 6,47E-03 ! positive regulation of histone modification GO:0031058 5 5 1,000 5,001E-04 6,435E-03 ! anagen GO:0042640 6 5 1,000 5,001E-04 6,401E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 5,001E-04 6,367E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 5,001E-04 6,333E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 5,001E-04 6,3E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 5,001E-04 6,267E-03 ! valine metabolic process GO:0006573 10 5 1,000 5,001E-04 6,235E-03 ! muscle cell migration GO:0014812 8 5 1,000 5,001E-04 6,203E-03 ! mRNA transcription GO:0009299 9 5 1,000 5,001E-04 6,171E-03 ! nerve growth factor processing GO:0032455 8 5 1,000 5,001E-04 6,139E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 5,001E-04 6,108E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 5,001E-04 6,077E-03 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 1,000 5,001E-04 6,047E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 5,001E-04 6,017E-03 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 5,001E-04 5,987E-03 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 5,228E-04 6,227E-03 ! negative regulation of multicellular organismal process GO:0051241 166 93 4,000 5,525E-04 6,549E-03 ! cell maturation GO:0048469 100 53 3,000 5,623E-04 6,632E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 5,718E-04 6,711E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 5,718E-04 6,678E-03 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 2,000 5,718E-04 6,646E-03 ! regulation of viral reproduction GO:0050792 38 23 2,000 5,718E-04 6,614E-03 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 6,477E-04 7,457E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 6,477E-04 7,421E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 6,5E-04 7,412E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 6,5E-04 7,377E-03 ! vasculogenesis GO:0001570 46 25 2,000 7,348E-04 8,3E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 7,348E-04 8,261E-03 ! neural crest cell development GO:0014032 54 25 2,000 7,348E-04 8,223E-03 GO:0014033|neural crest cell differentiation, ! somitogenesis GO:0001756 43 25 2,000 7,348E-04 8,185E-03 ! regulation of blood coagulation GO:0030193 40 25 2,000 7,348E-04 8,147E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 7,467E-04 8,241E-03 ! neuron remodeling GO:0016322 15 6 1,000 7,467E-04 8,203E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 7,467E-04 8,166E-03 ! toxin metabolic process GO:0009404 11 6 1,000 7,467E-04 8,129E-03 ! neuron apoptosis GO:0051402 9 6 1,000 7,467E-04 8,092E-03 ! negative regulation of platelet activation GO:0010544 9 6 1,000 7,467E-04 8,056E-03 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 1,000 7,467E-04 8,02E-03 ! neuronal ion channel clustering GO:0045161 12 6 1,000 7,467E-04 7,984E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 7,467E-04 7,949E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 7,467E-04 7,914E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 1,000 7,467E-04 7,879E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 7,467E-04 7,845E-03 ! hair follicle maturation GO:0048820 7 6 1,000 7,467E-04 7,811E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 7,467E-04 7,777E-03 ! molting cycle process GO:0022404 50 26 2,000 8,263E-04 8,569E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 8,263E-04 8,532E-03 GO:0045936|negative regulation of phosphate metabolic process, ! DNA catabolic process GO:0006308 86 59 3,000 8,454E-04 8,692E-03 ! protein amino acid acylation GO:0043543 55 27 2,000 9,247E-04 9,467E-03 ! fat cell differentiation GO:0045444 50 27 2,000 9,247E-04 9,427E-03 ! male gonad development GO:0008584 44 27 2,000 9,247E-04 9,387E-03 ! response to toxin GO:0009636 47 27 2,000 9,247E-04 9,348E-03 ! negative regulation of neuron differentiation GO:0045665 42 27 2,000 9,247E-04 9,309E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 9,247E-04 9,27E-03 ! ear development GO:0043583 103 62 3,000 1,019E-03 0,0101734 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,03E-03 0,01024271 ! prostate gland development GO:0030850 13 7 1,000 1,04E-03 0,0103015 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 1,04E-03 0,01025928 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,04E-03 0,0102174 ! mRNA stabilization GO:0048255 18 7 1,000 1,04E-03 0,01017587 GO:0043489|RNA stabilization, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 1,04E-03 0,01013467 ! regulation of gluconeogenesis GO:0006111 7 7 1,000 1,04E-03 0,0100938 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,04E-03 0,01005327 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 1,000 1,04E-03 0,01001305 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 1,04E-03 9,973E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 1,04E-03 9,934E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 1,04E-03 9,894E-03 ! organ growth GO:0035265 15 7 1,000 1,04E-03 9,855E-03 ! macrophage differentiation GO:0030225 11 7 1,000 1,04E-03 9,817E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,04E-03 9,778E-03 ! fibrinolysis GO:0042730 10 7 1,000 1,04E-03 9,74E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,04E-03 9,703E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,04E-03 9,665E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,04E-03 9,628E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 1,04E-03 9,591E-03 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 1,04E-03 9,554E-03 ! regulation of mitosis GO:0007088 105 63 3,000 1,082E-03 9,899E-03 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 3,000 1,082E-03 9,862E-03 ! regulation of coagulation GO:0050818 46 29 2,000 1,143E-03 0,01037837 ! germ cell development GO:0007281 118 65 3,000 1,216E-03 0,01100202 ! myeloid cell differentiation GO:0030099 111 65 3,000 1,216E-03 0,01096081 ! cell junction assembly GO:0034329 78 30 2,000 1,263E-03 0,01134275 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 1,263E-03 0,01130059 ! response to heat GO:0009408 50 30 2,000 1,263E-03 0,01125873 ! actin filament organization GO:0007015 148 66 3,000 1,288E-03 0,01143215 ! chromosome segregation GO:0007059 113 67 3,000 1,362E-03 0,01204632 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 1,381E-03 0,01216847 ! signal peptide processing GO:0006465 12 8 1,000 1,381E-03 0,01212406 ! succinate metabolic process GO:0006105 14 8 1,000 1,381E-03 0,01207997 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,381E-03 0,0120362 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,381E-03 0,01199275 ! pigment granule organization GO:0048753 16 8 1,000 1,381E-03 0,01194961 ! ER overload response GO:0006983 12 8 1,000 1,381E-03 0,01190678 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,381E-03 0,01186425 ! melanin metabolic process GO:0006582 15 8 1,000 1,381E-03 0,01182203 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,381E-03 0,01178011 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,381E-03 0,01173849 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,381E-03 0,01169715 ! negative regulation of translational initiation GO:0045947 10 8 1,000 1,381E-03 0,01165611 ! response to UV-B GO:0010224 16 8 1,000 1,381E-03 0,01161535 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,381E-03 0,01157488 ! DNA topological change GO:0006265 12 8 1,000 1,381E-03 0,01153469 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,381E-03 0,01149478 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,381E-03 0,01145514 ! erythrocyte differentiation GO:0030218 55 31 2,000 1,391E-03 0,01150497 ! negative regulation of ligase activity GO:0051352 112 68 3,000 1,439E-03 0,01185664 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 1,439E-03 0,01181617 ! cell cycle checkpoint GO:0000075 137 69 3,000 1,519E-03 0,01243156 ! response to ionizing radiation GO:0010212 65 32 2,000 1,527E-03 0,0124575 ! appendage morphogenesis GO:0035107 135 70 3,000 1,602E-03 0,01302353 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 3,000 1,602E-03 0,01297968 ! reproductive structure development GO:0048608 113 71 3,000 1,689E-03 0,01363269 ! appendage development GO:0048736 136 71 3,000 1,689E-03 0,01358709 GO:0060173|limb development, ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,767E-03 0,0141702 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 1,767E-03 0,01412313 ! regulation of histone modification GO:0031056 12 9 1,000 1,767E-03 0,01407636 ! microtubule bundle formation GO:0001578 21 9 1,000 1,767E-03 0,0140299 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,767E-03 0,01398375 ! T cell selection GO:0045058 23 9 1,000 1,767E-03 0,01393791 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,767E-03 0,01389236 GO:0006600|creatine metabolic process, ! receptor clustering GO:0043113 18 9 1,000 1,767E-03 0,0138471 ! behavioral fear response GO:0001662 22 9 1,000 1,767E-03 0,01380215 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 16 9 1,000 1,767E-03 0,01375748 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,767E-03 0,0137131 ! segment specification GO:0007379 13 9 1,000 1,767E-03 0,01366901 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,767E-03 0,0136252 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 1,767E-03 0,01358166 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,767E-03 0,01353841 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,767E-03 0,01349543 ! regulation of synaptogenesis GO:0051963 15 9 1,000 1,767E-03 0,01345272 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,767E-03 0,01341029 ! placenta development GO:0001890 53 34 2,000 1,824E-03 0,01379695 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,984E-03 0,0149645 ! cytokine production GO:0001816 59 35 2,000 1,984E-03 0,01491774 ! cell-matrix adhesion GO:0007160 163 75 3,000 2,066E-03 0,01548487 ! cell junction organization GO:0034330 86 36 2,000 2,153E-03 0,01608834 ! embryonic organ development GO:0048568 57 36 2,000 2,153E-03 0,01603853 ! regulation of catabolic process GO:0009894 161 76 3,000 2,169E-03 0,01610443 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 2,198E-03 0,01627345 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,198E-03 0,01622353 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 2,198E-03 0,01617391 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 2,198E-03 0,0161246 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 2,198E-03 0,01607559 ! lung alveolus development GO:0048286 26 10 1,000 2,198E-03 0,01602688 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 2,198E-03 0,01597846 ! glucan biosynthetic process GO:0009250 14 10 1,000 2,198E-03 0,01593033 GO:0005978|glycogen biosynthetic process, ! B cell proliferation GO:0042100 18 10 1,000 2,198E-03 0,01588249 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 2,198E-03 0,01583494 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,198E-03 0,01578767 ! regulation of bone resorption GO:0045124 25 10 1,000 2,198E-03 0,01574068 ! regulation of gliogenesis GO:0014013 23 10 1,000 2,198E-03 0,01569398 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 1,000 2,198E-03 0,01564754 ! DNA ligation GO:0006266 19 10 1,000 2,198E-03 0,01560139 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 2,198E-03 0,0155555 ! oocyte development GO:0048599 17 10 1,000 2,198E-03 0,01550988 ! response to nicotine GO:0035094 20 10 1,000 2,198E-03 0,01546453 ! localization within membrane GO:0051668 20 10 1,000 2,198E-03 0,01541945 ! tissue remodeling GO:0048771 76 37 2,000 2,331E-03 0,01630263 ! glycogen metabolic process GO:0005977 61 37 2,000 2,331E-03 0,01625538 ! pigment metabolic process GO:0042440 80 37 2,000 2,331E-03 0,0162084 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,517E-03 0,01745538 ! erythrocyte homeostasis GO:0034101 64 38 2,000 2,517E-03 0,01740522 ! embryonic epithelial tube formation GO:0001838 72 38 2,000 2,517E-03 0,01735535 ! glucan metabolic process GO:0044042 62 38 2,000 2,517E-03 0,01730577 GO:0006073|cellular glucan metabolic process, ! negative regulation of muscle development GO:0048635 20 11 1,000 2,674E-03 0,01833001 ! neuron fate specification GO:0048665 17 11 1,000 2,674E-03 0,01827794 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,674E-03 0,01822616 ! blood vessel remodeling GO:0001974 29 11 1,000 2,674E-03 0,01817467 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,674E-03 0,01812347 GO:0010812|negative regulation of cell-substrate adhesion, ! ventral spinal cord development GO:0021517 21 11 1,000 2,674E-03 0,01807257 ! substrate-bound cell migration GO:0006929 13 11 1,000 2,674E-03 0,01802194 ! temperature homeostasis GO:0001659 17 11 1,000 2,674E-03 0,0179716 ! negative regulation of ossification GO:0030279 26 11 1,000 2,674E-03 0,01792154 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 2,674E-03 0,01787176 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 2,674E-03 0,01782225 ! neuroblast proliferation GO:0007405 24 11 1,000 2,674E-03 0,01777302 ! oocyte differentiation GO:0009994 18 11 1,000 2,674E-03 0,01772406 ! thymus development GO:0048538 27 11 1,000 2,674E-03 0,01767537 ! embryonic gut development GO:0048566 15 11 1,000 2,674E-03 0,01762694 ! regulation of embryonic development GO:0045995 27 11 1,000 2,674E-03 0,01757878 ! regulation of synapse organization GO:0050807 17 11 1,000 2,674E-03 0,01753088 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 2,713E-03 0,01773785 ! segmentation GO:0035282 67 39 2,000 2,713E-03 0,01768978 ! cell-substrate adhesion GO:0031589 171 81 3,000 2,736E-03 0,01778885 ! regulation of neuron differentiation GO:0045664 167 81 3,000 2,736E-03 0,0177409 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 2,918E-03 0,01887091 ! regulation of T cell proliferation GO:0042129 71 41 2,000 3,132E-03 0,02020025 ! T cell differentiation GO:0030217 81 41 2,000 3,132E-03 0,02014624 ! virus-host interaction GO:0019048 29 12 1,000 3,194E-03 0,02049169 ! cartilage condensation GO:0001502 20 12 1,000 3,194E-03 0,02043719 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 3,194E-03 0,02038298 GO:0050927|positive regulation of positive chemotaxis, ! hippocampus development GO:0021766 26 12 1,000 3,194E-03 0,02032905 ! cytokine biosynthetic process GO:0042089 21 12 1,000 3,194E-03 0,02027541 ! positive regulation of cell growth GO:0030307 22 12 1,000 3,194E-03 0,02022206 ! membrane protein proteolysis GO:0033619 25 12 1,000 3,194E-03 0,02016898 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 26 12 1,000 3,194E-03 0,02011618 ! autonomic nervous system development GO:0048483 24 12 1,000 3,194E-03 0,02006366 ! gland morphogenesis GO:0022612 29 12 1,000 3,194E-03 0,02001141 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 3,194E-03 0,01995943 ! spleen development GO:0048536 22 12 1,000 3,194E-03 0,01990773 ! digestive tract morphogenesis GO:0048546 26 12 1,000 3,194E-03 0,01985628 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of synapse structure and activity GO:0050803 18 12 1,000 3,194E-03 0,01980511 ! neuron migration GO:0001764 79 42 2,000 3,355E-03 0,02075062 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 3,355E-03 0,02069741 ! energy reserve metabolic process GO:0006112 74 43 2,000 3,588E-03 0,02207717 ! glucose transport GO:0015758 65 43 2,000 3,588E-03 0,02202085 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,588E-03 0,02196482 ! positive regulation of protein modification process GO:0031401 136 88 3,000 3,689E-03 0,02252622 ! regulation of chemokine production GO:0032642 18 13 1,000 3,757E-03 0,02288345 ! positive regulation of lipid metabolic process GO:0045834 25 13 1,000 3,757E-03 0,02282567 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 3,757E-03 0,02276817 ! Golgi organization GO:0007030 24 13 1,000 3,757E-03 0,02271097 ! cytokine metabolic process GO:0042107 22 13 1,000 3,757E-03 0,02265405 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 3,757E-03 0,02259741 ! regulation of mRNA stability GO:0043488 31 13 1,000 3,757E-03 0,02254106 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 3,757E-03 0,02248499 ! embryonic placenta development GO:0001892 23 13 1,000 3,757E-03 0,02242919 ! hexose transport GO:0008645 67 44 2,000 3,83E-03 0,02281075 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 2,000 3,83E-03 0,02275443 ! developmental growth GO:0048589 82 44 2,000 3,83E-03 0,02269838 ! sex differentiation GO:0007548 145 90 3,000 3,998E-03 0,02363273 ! cell growth GO:0016049 84 45 2,000 4,082E-03 0,02407447 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,345E-03 0,02555738 ! hair follicle morphogenesis GO:0031069 26 14 1,000 4,362E-03 0,02560011 ! regulation of mRNA processing GO:0050684 24 14 1,000 4,362E-03 0,02553783 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 4,362E-03 0,02547584 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 1,000 4,362E-03 0,02541416 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 4,362E-03 0,02535277 ! response to gamma radiation GO:0010332 28 14 1,000 4,362E-03 0,02529168 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 4,362E-03 0,02523088 ! regulation of RNA stability GO:0043487 32 14 1,000 4,362E-03 0,02517037 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 4,493E-03 0,02586245 GO:0010498|proteasomal protein catabolic process, ! Notch signaling pathway GO:0007219 96 48 2,000 4,899E-03 0,02812995 ! morphogenesis of embryonic epithelium GO:0016331 91 48 2,000 4,899E-03 0,02806297 ! activation of caspase activity GO:0006919 84 48 2,000 4,899E-03 0,02799631 ! positive regulation of cell size GO:0045793 27 15 1,000 5,01E-03 0,02856424 ! cardiac muscle contraction GO:0060048 26 15 1,000 5,01E-03 0,02849671 ! G1/S transition checkpoint GO:0031575 40 15 1,000 5,01E-03 0,0284295 ! mRNA splice site selection GO:0006376 38 15 1,000 5,01E-03 0,02836261 ! muscle maintenance GO:0046716 26 15 1,000 5,01E-03 0,02829603 ! heme biosynthetic process GO:0006783 29 15 1,000 5,01E-03 0,02822976 ! peptide hormone processing GO:0016486 23 15 1,000 5,01E-03 0,0281638 ! leukocyte differentiation GO:0002521 202 96 3,000 5,028E-03 0,02820085 ! peptide metabolic process GO:0006518 76 49 2,000 5,191E-03 0,02904615 ! response to temperature stimulus GO:0009266 76 49 2,000 5,191E-03 0,02897876 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 5,216E-03 0,02904913 ! regulation of protein localization GO:0032880 176 97 3,000 5,216E-03 0,02898205 ! histone modification GO:0016570 91 50 2,000 5,494E-03 0,03045623 ! negative regulation of immune system process GO:0002683 95 50 2,000 5,494E-03 0,03038622 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 5,699E-03 0,03144873 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 5,699E-03 0,03137677 ! activation of MAPKK activity GO:0000186 35 16 1,000 5,699E-03 0,03130513 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 5,699E-03 0,03123382 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 5,699E-03 0,03116284 GO:0031114|regulation of microtubule depolymerization, ! defense response to virus GO:0051607 37 16 1,000 5,699E-03 0,03109217 ! regulation of angiogenesis GO:0045765 114 52 2,000 6,13E-03 0,03336996 ! covalent chromatin modification GO:0016569 101 52 2,000 6,13E-03 0,03329463 ! cartilage development GO:0051216 90 52 2,000 6,13E-03 0,03321964 ! metencephalon development GO:0022037 30 17 1,000 6,429E-03 0,03475771 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 6,429E-03 0,03467977 ! signal complex assembly GO:0007172 41 17 1,000 6,429E-03 0,03460219 ! limbic system development GO:0021761 36 17 1,000 6,429E-03 0,03452495 ! heart looping GO:0001947 30 17 1,000 6,429E-03 0,03444806 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 6,429E-03 0,03437151 ! regulation of protein binding GO:0043393 33 17 1,000 6,429E-03 0,0342953 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 6,429E-03 0,03421942 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 6,429E-03 0,03414388 ! positive regulation of caspase activity GO:0043280 95 55 2,000 7,165E-03 0,03796913 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 7,165E-03 0,03788568 ! aging GO:0007568 103 55 2,000 7,165E-03 0,0378026 ! heart morphogenesis GO:0003007 97 55 2,000 7,165E-03 0,03771988 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 7,198E-03 0,03781492 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,198E-03 0,03773253 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 7,198E-03 0,0376505 GO:0050886|endocrine process, ! patterning of blood vessels GO:0001569 39 18 1,000 7,198E-03 0,03756883 ! positive regulation of proteolysis GO:0045862 31 18 1,000 7,198E-03 0,03748751 ! epidermis morphogenesis GO:0048730 40 18 1,000 7,198E-03 0,03740655 ! peptide biosynthetic process GO:0043043 24 18 1,000 7,198E-03 0,03732593 ! porphyrin biosynthetic process GO:0006779 33 18 1,000 7,198E-03 0,03724566 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of DNA replication GO:0006275 101 56 2,000 7,531E-03 0,03888251 ! regulation of bone remodeling GO:0046850 137 57 2,000 7,908E-03 0,04074241 ! protein secretion GO:0009306 39 19 1,000 8,008E-03 0,04116742 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 8,008E-03 0,04107964 ! lipid phosphorylation GO:0046834 35 19 1,000 8,008E-03 0,04099224 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 8,008E-03 0,04090521 ! forelimb morphogenesis GO:0035136 32 19 1,000 8,008E-03 0,04081854 ! pigmentation during development GO:0048066 41 19 1,000 8,008E-03 0,04073224 ! cellular response to unfolded protein GO:0034620 33 19 1,000 8,008E-03 0,04064631 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 1,000 8,008E-03 0,04056074 ! actin filament bundle formation GO:0051017 42 19 1,000 8,008E-03 0,04047553 ! neuromuscular junction development GO:0007528 34 19 1,000 8,008E-03 0,04039067 ! heart process GO:0003015 30 19 1,000 8,008E-03 0,04030618 GO:0060047|heart contraction, ! cellular pigmentation GO:0033059 36 19 1,000 8,008E-03 0,04022203 ! proximal/distal pattern formation GO:0009954 32 19 1,000 8,008E-03 0,04013823 ! regulation of tissue remodeling GO:0034103 140 58 2,000 8,296E-03 0,04149798 ! skeletal system morphogenesis GO:0048705 105 59 2,000 8,695E-03 0,04340432 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 8,695E-03 0,04331446 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 8,856E-03 0,04402293 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 8,856E-03 0,04393216 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 8,856E-03 0,04384177 ! hindlimb morphogenesis GO:0035137 43 21 1,000 9,742E-03 0,04813153 ! ovarian follicle development GO:0001541 35 21 1,000 9,742E-03 0,0480329 ! cell aging GO:0007569 44 21 1,000 9,742E-03 0,04793467 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 9,742E-03 0,04783684 ! oogenesis GO:0048477 36 21 1,000 9,742E-03 0,04773942 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 9,742E-03 0,04764238 ! viral reproductive process GO:0022415 126 62 2,000 9,96E-03 0,04860577 ! gonad development GO:0008406 98 62 2,000 9,96E-03 0,04850737 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 0,01066658 0,05184607 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 0,01066658 0,05174154 ! regeneration GO:0031099 41 22 1,000 0,01066658 0,05163743 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 0,01066658 0,05153374 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 0,01066658 0,05143047 ! positive regulation of B cell activation GO:0050871 38 22 1,000 0,01066658 0,05132761 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 0,01066658 0,05122516 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 0,01066658 0,05112311 ! protein stabilization GO:0050821 39 22 1,000 0,01066658 0,05102148 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 0,01132516 0,05406416 GO:0035113|embryonic appendage morphogenesis, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 0,011628 0,05539992 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 0,011628 0,05529043 ! response to ethanol GO:0045471 46 23 1,000 0,011628 0,05518138 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 0,011628 0,05507275 ! secondary metabolic process GO:0019748 116 66 2,000 0,01180314 0,05579243 ! lung development GO:0030324 144 67 2,000 0,01229257 0,05799201 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 0,01229257 0,05787853 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01262599 0,0593323 ! spinal cord development GO:0021510 47 24 1,000 0,01262599 0,05921665 ! multicellular organismal response to stress GO:0033555 49 24 1,000 0,01262599 0,05910144 ! lymphocyte proliferation GO:0046651 48 24 1,000 0,01262599 0,05898668 ! pallium development GO:0021543 49 24 1,000 0,01262599 0,05887236 ! porphyrin metabolic process GO:0006778 46 24 1,000 0,01262599 0,05875849 GO:0033013|tetrapyrrole metabolic process, ! protein tetramerization GO:0051262 52 24 1,000 0,01262599 0,05864506 ! viral reproduction GO:0016032 134 68 2,000 0,01279351 0,05930863 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 0,01366001 0,06320382 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01366001 0,06308251 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 0,01366001 0,06296166 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01366001 0,06284127 ! receptor metabolic process GO:0043112 46 25 1,000 0,01366001 0,06272135 ! chromosome condensation GO:0030261 45 25 1,000 0,01366001 0,06260188 ! response to starvation GO:0042594 42 25 1,000 0,01366001 0,06248286 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01366001 0,0623643 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 0,01366001 0,06224619 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01366001 0,06212852 ! neural tube closure GO:0001843 49 25 1,000 0,01366001 0,0620113 GO:0060606|tube closure, ! embryonic pattern specification GO:0009880 44 26 1,000 0,01472949 0,0667404 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 0,01472949 0,06661494 ! tube lumen formation GO:0035148 50 26 1,000 0,01472949 0,06648996 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 0,01472949 0,06636545 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01472949 0,0662414 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01472949 0,06611782 GO:0032943|mononuclear cell proliferation, ! regulation of caspase activity GO:0043281 122 72 2,000 0,01491298 0,06681681 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 0,01491298 0,06669261 ! carbohydrate transport GO:0008643 110 72 2,000 0,01491298 0,06656888 ! respiratory system development GO:0060541 153 72 2,000 0,01491298 0,0664456 ! neuron fate commitment GO:0048663 48 27 1,000 0,01583387 0,07041829 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01583387 0,07028837 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01583387 0,07015893 ! primary neural tube formation GO:0014020 51 27 1,000 0,01583387 0,07002996 ! glutathione metabolic process GO:0006749 39 27 1,000 0,01583387 0,06990146 ! regulation of transcription factor activity GO:0051090 126 74 2,000 0,01604258 0,07069314 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01604258 0,07056391 ! eye development GO:0001654 143 74 2,000 0,01604258 0,07043514 ! lymphocyte differentiation GO:0030098 167 75 2,000 0,01662494 0,07285905 ! dendrite development GO:0016358 59 28 1,000 0,01697261 0,07424747 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01697261 0,07411272 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01697261 0,07397846 ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01721904 0,07491682 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01814517 0,07880376 ! cell fate determination GO:0001709 60 29 1,000 0,01814517 0,07866177 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01814517 0,07852029 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01814517 0,07837932 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01814517 0,07823886 ! tissue homeostasis GO:0001894 48 29 1,000 0,01814517 0,0780989 GO:0048871|multicellular organismal homeostasis, ! blood coagulation GO:0007596 146 78 2,000 0,01844249 0,07923685 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01844249 0,0790956 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 0,01844249 0,07895487 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,01907188 0,08150434 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01907188 0,08135983 ! determination of left/right symmetry GO:0007368 47 30 1,000 0,01935101 0,08240447 ! response to metal ion GO:0010038 140 80 2,000 0,01971306 0,08379792 ! T cell activation GO:0042110 168 81 2,000 0,02036604 0,08642097 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,0205896 0,08721579 ! determination of bilateral symmetry GO:0009855 49 31 1,000 0,0205896 0,08706251 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 1,000 0,0205896 0,08690977 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,0205896 0,08675756 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,0205896 0,08660589 ! ovulation cycle process GO:0022602 49 31 1,000 0,0205896 0,08645474 ! myeloid leukocyte activation GO:0002274 49 31 1,000 0,0205896 0,08630413 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,0205896 0,08615403 GO:0043433|negative regulation of transcription factor activity, ! response to drug GO:0042493 143 82 2,000 0,02103082 0,08784751 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,02186041 0,09115449 ! spliceosome assembly GO:0000245 67 32 1,000 0,02186041 0,09099678 ! spindle organization GO:0007051 46 32 1,000 0,02186041 0,09083962 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,02186041 0,090683 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,02186041 0,09052692 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,02186041 0,09037138 ! ovulation cycle GO:0042698 51 32 1,000 0,02186041 0,09021637 ! hindbrain development GO:0030902 61 32 1,000 0,02186041 0,09006189 ! hemostasis GO:0007599 158 84 2,000 0,02239583 0,09211001 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,02316293 0,09510239 ! post-embryonic development GO:0009791 69 33 1,000 0,02316293 0,09494038 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,02316293 0,09477891 ! cell fate specification GO:0001708 52 33 1,000 0,02316293 0,094618 ! response to inorganic substance GO:0010035 153 86 2,000 0,02380807 0,09708852 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,02449664 0,09972743 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,02449664 0,09955897 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,02449664 0,09939108 ! protein localization in nucleus GO:0034504 176 87 2,000 0,02453191 0,09936663 ! regulation of protein transport GO:0051223 154 87 2,000 0,02453191 0,09919963 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 2,000 0,02526755 0,10200289 ! gland development GO:0048732 206 88 2,000 0,02526755 0,10183203 ! negative regulation of secretion GO:0051048 63 35 1,000 0,02586104 0,10404959 ! female gonad development GO:0008585 58 35 1,000 0,02586104 0,10387588 ! telencephalon development GO:0021537 68 35 1,000 0,02586104 0,10370276 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,02586104 0,1035302 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,02586104 0,10335823 ! neural tube formation GO:0001841 67 35 1,000 0,02586104 0,10318682 ! ossification GO:0001503 188 90 2,000 0,0267742 0,10665351 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02725562 0,10839177 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,02725562 0,1082129 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02725562 0,10803463 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02725562 0,10785694 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,02725562 0,10767983 ! regulation of proteolysis GO:0030162 72 36 1,000 0,02725562 0,10750331 ! bone development GO:0060348 189 91 2,000 0,02754519 0,10846762 ! response to protein stimulus GO:0051789 149 91 2,000 0,02754519 0,10829039 ! meiosis I GO:0007127 65 37 1,000 0,02867989 0,1125674 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02867989 0,11238406 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,02867989 0,11220132 ! female pregnancy GO:0007565 164 94 2,000 0,02992865 0,11689664 ! transcription initiation GO:0006352 153 94 2,000 0,02992865 0,11670718 ! regulation of T cell activation GO:0050863 158 94 2,000 0,02992865 0,11651833 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,03013336 0,11712578 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,03013336 0,11693687 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 1,000 0,03013336 0,11674856 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,03013336 0,11656086 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! forebrain development GO:0030900 188 95 2,000 0,03074658 0,11874201 ! ear morphogenesis GO:0042471 60 39 1,000 0,03161554 0,12190222 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,03312595 0,12752166 ! negative regulation of binding GO:0051100 72 40 1,000 0,03312595 0,12731795 ! maintenance of protein location GO:0045185 91 40 1,000 0,03312595 0,12711489 ! cytokinesis GO:0000910 72 40 1,000 0,03312595 0,12691248 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,03413498 0,13057036 GO:0060538|skeletal muscle organ development, ! cellular amide metabolic process GO:0043603 67 41 1,000 0,03466412 0,13238393 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,03466412 0,13217413 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,03466412 0,13196499 ! female gamete generation GO:0007292 61 41 1,000 0,03466412 0,13175652 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03519043 0,133546 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03519043 0,1333357 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03519043 0,13312605 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03519043 0,13291706 ! neuron fate determination GO:0048664 7 5 0,000 0,03519043 0,13270873 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03519043 0,13250104 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03519043 0,13229401 ! polyol transport GO:0015791 12 5 0,000 0,03519043 0,13208762 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03519043 0,13188188 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03519043 0,13167678 ! response to superoxide GO:0000303 10 5 0,000 0,03519043 0,13147231 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03519043 0,13126848 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03519043 0,13106527 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03519043 0,1308627 ! female meiosis GO:0007143 7 5 0,000 0,03519043 0,13066075 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03519043 0,13045943 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03519043 0,13025872 ! cobalt ion transport GO:0006824 11 5 0,000 0,03519043 0,13005863 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03519043 0,12985915 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03519043 0,12966029 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03519043 0,12946203 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03519043 0,12926438 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03519043 0,12906733 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03519043 0,12887088 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03519043 0,12867503 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03519043 0,12847977 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03519043 0,1282851 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03519043 0,12809102 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03519043 0,12789753 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03519043 0,12770463 ! negative chemotaxis GO:0050919 14 5 0,000 0,03519043 0,1275123 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03519043 0,12732055 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03519043 0,12712938 ! behavioral response to pain GO:0048266 9 5 0,000 0,03519043 0,12693878 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03519043 0,12674875 ! Notch receptor processing GO:0007220 8 5 0,000 0,03519043 0,12655929 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03519043 0,1263704 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03519043 0,12618207 ! micturition GO:0060073 9 5 0,000 0,03519043 0,1259943 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03519043 0,12580708 ! copulation GO:0007620 9 5 0,000 0,03519043 0,12562043 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03519043 0,12543432 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03519043 0,12524877 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03519043 0,12506376 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03519043 0,1248793 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03519043 0,12469539 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03519043 0,12451201 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03519043 0,12432917 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03519043 0,12414687 ! grooming behavior GO:0007625 6 5 0,000 0,03519043 0,12396511 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03519043 0,12378387 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03519043 0,12360316 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03519043 0,12342298 ! response to protozoan GO:0001562 10 5 0,000 0,03519043 0,12324333 ! lymph vessel development GO:0001945 10 5 0,000 0,03519043 0,1230642 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03519043 0,12288558 ! endochondral ossification GO:0001958 16 5 0,000 0,03519043 0,12270749 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03519043 0,12252991 ! parathyroid gland development GO:0060017 13 5 0,000 0,03519043 0,12235284 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03519043 0,12217629 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03519043 0,12200024 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03519043 0,1218247 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03519043 0,12164967 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03519043 0,12147513 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03519043 0,1213011 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03519043 0,12112756 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03519043 0,12095452 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03519043 0,12078198 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03519043 0,12060992 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03519043 0,12043836 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03519043 0,12026728 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03519043 0,12009669 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03519043 0,11992658 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03519043 0,11975695 ! histidine catabolic process GO:0006548 6 5 0,000 0,03519043 0,11958781 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03519043 0,11941914 ! microvillus organization GO:0032528 7 5 0,000 0,03519043 0,11925094 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03519043 0,11908322 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03519043 0,11891596 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03519043 0,11874918 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03519043 0,11858287 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03519043 0,11841702 ! polyol catabolic process GO:0046174 7 5 0,000 0,03519043 0,11825163 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03519043 0,1180867 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03519043 0,11792224 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03519043 0,11775823 ! mitochondrial fission GO:0000266 8 5 0,000 0,03519043 0,11759468 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03519043 0,11743158 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03519043 0,11726893 GO:0009253|peptidoglycan catabolic process, ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03519043 0,11710673 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03519043 0,11694498 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03519043 0,11678368 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03519043 0,11662282 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03519043 0,1164624 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03519043 0,11630243 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03519043 0,11614289 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03519043 0,11598379 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03519043 0,11582513 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03519043 0,11566689 ! forebrain neuron development GO:0021884 13 5 0,000 0,03519043 0,1155091 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03519043 0,11535173 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03519043 0,11519478 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03519043 0,11503827 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03519043 0,11488218 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03519043 0,11472651 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03519043 0,11457127 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03519043 0,11441644 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03519043 0,11426203 ! basic amino acid transport GO:0015802 11 5 0,000 0,03519043 0,11410804 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03519043 0,11395446 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03519043 0,1138013 ! depyrimidination GO:0045008 10 5 0,000 0,03519043 0,11364855 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03519043 0,1134962 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03519043 0,11334427 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03519043 0,11319274 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03519043 0,11304161 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03519043 0,11289089 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03519043 0,11274057 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03519043 0,11259065 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03519043 0,11244112 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03519043 0,112292 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03519043 0,11214327 ! response to arsenic GO:0046685 10 5 0,000 0,03519043 0,11199493 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03519043 0,11184698 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03519043 0,11169943 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03519043 0,11155226 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03519043 0,11140548 ! response to cadmium ion GO:0046686 7 5 0,000 0,03519043 0,11125909 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03519043 0,11111308 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03519043 0,11096745 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03519043 0,11082221 ! decidualization GO:0046697 11 5 0,000 0,03519043 0,11067734 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03519043 0,11053285 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03519043 0,11038874 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03519043 0,11024501 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03519043 0,11010165 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03519043 0,10995866 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03519043 0,10981604 ! neural tube patterning GO:0021532 7 5 0,000 0,03519043 0,10967379 ! embryonic cleavage GO:0040016 6 5 0,000 0,03519043 0,10953191 ! peroxisome fission GO:0016559 5 5 0,000 0,03519043 0,1093904 ! histone demethylation GO:0016577 10 5 0,000 0,03519043 0,10924925 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03519043 0,10910846 ! mitotic recombination GO:0006312 9 5 0,000 0,03519043 0,10896804 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03519043 0,10882798 ! metaphase plate congression GO:0051310 7 5 0,000 0,03519043 0,10868828 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03519043 0,10854893 GO:0032374|regulation of cholesterol transport, ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03519043 0,10840994 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03519043 0,10827131 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03519043 0,10813304 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03519043 0,10799511 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03519043 0,10785754 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03519043 0,10772031 ! plasminogen activation GO:0031639 5 5 0,000 0,03519043 0,10758344 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03519043 0,10744691 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03519043 0,10731073 ! metaphase GO:0051323 8 5 0,000 0,03519043 0,10717489 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03519043 0,1070394 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03519043 0,10690425 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03519043 0,10676944 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03519043 0,10663497 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03519043 0,10650084 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03519043 0,10636704 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03519043 0,10623358 ! response to redox state GO:0051775 5 5 0,000 0,03519043 0,10610046 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03519043 0,10596767 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03519043 0,10583521 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03519043 0,10570308 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03519043 0,10557128 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03519043 0,10543981 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03519043 0,10530867 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03519043 0,10517785 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03519043 0,10504735 ! striatum development GO:0021756 9 5 0,000 0,03519043 0,10491718 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03519043 0,10478734 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03519043 0,10465781 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03519043 0,1045286 ! glial cell migration GO:0008347 11 5 0,000 0,03519043 0,10439971 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03519043 0,10427114 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03519043 0,10414289 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03519043 0,10401495 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03519043 0,10388732 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03519043 0,10376001 ! neuroprotection GO:0043526 6 5 0,000 0,03519043 0,10363301 ! neural plate development GO:0001840 8 5 0,000 0,03519043 0,10350632 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03519043 0,10337994 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03519043 0,10325386 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03519043 0,1031281 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03519043 0,10300264 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03519043 0,10287748 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03519043 0,10275263 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03519043 0,10262808 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03519043 0,10250383 ! spindle assembly GO:0051225 6 5 0,000 0,03519043 0,10237989 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03519043 0,10225624 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03519043 0,10213289 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03519043 0,10200984 ! drug metabolic process GO:0017144 6 5 0,000 0,03519043 0,10188708 ! organ regeneration GO:0031100 7 5 0,000 0,03519043 0,10176462 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03519043 0,10164246 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03519043 0,10152058 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03519043 0,101399 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03622958 0,10426838 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,03622958 0,10414381 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03622958 0,10401953 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,03622958 0,10389555 ! regulation of protein secretion GO:0050708 71 42 1,000 0,03622958 0,10377187 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,03782186 0,10820381 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,03782186 0,1080753 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,03782186 0,1079471 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,03782186 0,1078192 ! neural tube development GO:0021915 77 43 1,000 0,03782186 0,1076916 ! striated muscle contraction GO:0006941 77 43 1,000 0,03782186 0,10756431 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,03782186 0,10743731 ! B cell differentiation GO:0030183 107 44 1,000 0,03944051 0,11190315 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,03944051 0,11177135 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03944051 0,11163985 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,04108507 0,11615827 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,04108507 0,11602193 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,04108507 0,11588591 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04207918 0,11855094 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04207918 0,11841228 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04207918 0,11827395 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04207918 0,11813594 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04207918 0,11799825 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04207918 0,11786089 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04207918 0,11772384 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04207918 0,11758711 ! sleep GO:0030431 13 6 0,000 0,04207918 0,1174507 ! response to oxygen radical GO:0000305 11 6 0,000 0,04207918 0,1173146 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04207918 0,11717882 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,04207918 0,11704335 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04207918 0,1169082 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04207918 0,11677336 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04207918 0,11663883 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04207918 0,1165046 ! forebrain regionalization GO:0021871 8 6 0,000 0,04207918 0,11637069 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04207918 0,11623708 ! male meiosis GO:0007140 7 6 0,000 0,04207918 0,11610379 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04207918 0,11597079 ! response to zinc ion GO:0010043 9 6 0,000 0,04207918 0,1158381 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04207918 0,11570572 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,04207918 0,11557363 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,04207918 0,11544185 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04207918 0,11531037 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04207918 0,11517918 ! malate metabolic process GO:0006108 11 6 0,000 0,04207918 0,1150483 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04207918 0,11491771 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04207918 0,11478742 ! protein refolding GO:0042026 15 6 0,000 0,04207918 0,11465742 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,04207918 0,11452772 ! opsonization GO:0008228 8 6 0,000 0,04207918 0,11439831 ! mating behavior GO:0007617 7 6 0,000 0,04207918 0,11426919 ! erythrocyte maturation GO:0043249 7 6 0,000 0,04207918 0,11414036 ! equilibrioception GO:0050957 14 6 0,000 0,04207918 0,11401183 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04207918 0,11388358 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04207918 0,11375562 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04207918 0,11362795 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,04207918 0,11350056 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04207918 0,11337346 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04207918 0,11324665 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04207918 0,11312011 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04207918 0,11299386 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,04207918 0,11286789 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,04207918 0,11274221 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,04207918 0,1126168 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04207918 0,11249167 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,04207918 0,11236682 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04207918 0,11224224 ! thymic T cell selection GO:0045061 12 6 0,000 0,04207918 0,11211794 ! protein lipoylation GO:0009249 10 6 0,000 0,04207918 0,11199392 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04207918 0,11187017 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,04207918 0,11174669 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04207918 0,11162348 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04207918 0,11150055 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,04207918 0,11137789 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,04207918 0,1112555 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,04207918 0,11113337 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,04207918 0,11101151 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04207918 0,11088992 ! hyperosmotic response GO:0006972 9 6 0,000 0,04207918 0,1107686 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04207918 0,11064754 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04207918 0,11052675 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04207918 0,11040622 ! urea metabolic process GO:0019627 7 6 0,000 0,04207918 0,11028595 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04207918 0,11016594 ! neutrophil activation GO:0042119 8 6 0,000 0,04207918 0,1100462 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04207918 0,10992671 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04207918 0,10980748 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04207918 0,10968852 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04207918 0,10956981 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04207918 0,10945135 ! nucleoside salvage GO:0043174 9 6 0,000 0,04207918 0,10933315 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04207918 0,10921521 ! T cell mediated immunity GO:0002456 16 6 0,000 0,04207918 0,10909752 ! carnitine transport GO:0015879 10 6 0,000 0,04207918 0,10898009 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04207918 0,1088629 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04207918 0,10874597 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04207918 0,10862929 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04207918 0,10851286 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04207918 0,10839668 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,04207918 0,10828075 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,04207918 0,10816506 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04207918 0,10804963 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,04207918 0,10793444 ! monocyte differentiation GO:0030224 12 6 0,000 0,04207918 0,10781949 ! response to UV-C GO:0010225 11 6 0,000 0,04207918 0,10770479 ! astrocyte development GO:0014002 15 6 0,000 0,04207918 0,10759033 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04207918 0,10747612 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04207918 0,10736214 ! interaction with symbiont GO:0051702 13 6 0,000 0,04207918 0,10724841 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04207918 0,10713492 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04207918 0,10702167 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,04207918 0,10690866 ! response to copper ion GO:0046688 10 6 0,000 0,04207918 0,10679589 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04207918 0,10668335 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04207918 0,10657105 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04207918 0,10645899 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04207918 0,10634716 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04207918 0,10623557 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04207918 0,10612421 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04207918 0,10601309 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04207918 0,1059022 ! Schwann cell development GO:0014044 15 6 0,000 0,04207918 0,10579154 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04207918 0,10568111 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04207918 0,10557091 ! subpallium development GO:0021544 10 6 0,000 0,04207918 0,10546094 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04207918 0,1053512 ! histone ubiquitination GO:0016574 8 6 0,000 0,04207918 0,10524168 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04207918 0,1051324 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04207918 0,10502334 ! G2 phase GO:0051319 16 6 0,000 0,04207918 0,10491451 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04207918 0,1048059 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04207918 0,10469752 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04207918 0,10458936 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04207918 0,10448142 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04207918 0,10437371 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04207918 0,10426622 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04207918 0,10415895 ! receptor internalization GO:0031623 10 6 0,000 0,04207918 0,1040519 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,04207918 0,10394507 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,04207918 0,10383846 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04207918 0,10373207 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,04207918 0,1036259 ! protein deubiquitination GO:0016579 14 6 0,000 0,04207918 0,10351994 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,04207918 0,1034142 ! protein destabilization GO:0031648 9 6 0,000 0,04207918 0,10330867 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04207918 0,10320336 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04207918 0,10309827 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04207918 0,10299339 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,04207918 0,10288872 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04207918 0,10278426 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04207918 0,10268002 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04207918 0,10257599 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04207918 0,10247217 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04207918 0,10236855 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,04207918 0,10226515 ! determination of adult lifespan GO:0008340 15 6 0,000 0,04207918 0,10216196 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,04207918 0,10205897 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04207918 0,10195619 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04207918 0,10185362 ! catecholamine transport GO:0051937 9 6 0,000 0,04207918 0,10175126 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04207918 0,1016491 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04207918 0,10154714 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04207918 0,10144539 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,04207918 0,10134384 ! maternal placenta development GO:0001893 12 6 0,000 0,04207918 0,1012425 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04207918 0,10114136 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04207918 0,10104042 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04207918 0,10093968 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04207918 0,10083914 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04207918 0,10073881 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04207918 0,10063867 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,0427551 0,10215369 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,0427551 0,10205234 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,0427551 0,1019512 ! positive regulation of defense response GO:0031349 76 47 1,000 0,04445014 0,10588816 ! response to calcium ion GO:0051592 81 47 1,000 0,04445014 0,10578342 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,04445014 0,10567889 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,04445014 0,10557457 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,04445014 0,10547045 ! mitochondrial transport GO:0006839 82 48 1,000 0,04616977 0,10944281 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,04616977 0,10933509 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,04616977 0,10922759 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,04616977 0,10912029 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,04791354 0,11313049 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,04791354 0,11301958 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,04791354 0,11290888 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,04791354 0,11279841 ! tRNA transcription GO:0009304 14 7 0,000 0,04891897 0,11505283 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04891897 0,11494047 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04891897 0,11482833 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04891897 0,11471641 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04891897 0,11460471 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04891897 0,11449323 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04891897 0,11438196 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04891897 0,11427091 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04891897 0,11416008 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04891897 0,11404946 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04891897 0,11393905 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04891897 0,11382886 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04891897 0,11371888 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04891897 0,11360911 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04891897 0,11349956 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04891897 0,11339021 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04891897 0,11328108 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04891897 0,11317215 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04891897 0,11306344 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04891897 0,11295493 ! glycolipid transport GO:0046836 10 7 0,000 0,04891897 0,11284664 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04891897 0,11273854 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04891897 0,11263066 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04891897 0,11252298 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04891897 0,11241551 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04891897 0,11230824 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04891897 0,11220118 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04891897 0,11209432 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04891897 0,11198767 ! pericardium development GO:0060039 14 7 0,000 0,04891897 0,11188122 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04891897 0,11177497 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04891897 0,11166892 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04891897 0,11156307 ! lipoprotein transport GO:0042953 14 7 0,000 0,04891897 0,11145742 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04891897 0,11135198 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04891897 0,11124673 ! rhythmic behavior GO:0007622 15 7 0,000 0,04891897 0,11114168 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04891897 0,11103683 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04891897 0,11093218 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04891897 0,11082772 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04891897 0,11072346 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04891897 0,1106194 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04891897 0,11051553 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04891897 0,11041186 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04891897 0,11030838 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04891897 0,11020509 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04891897 0,110102 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04891897 0,1099991 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04891897 0,1098964 ! spinal cord patterning GO:0021511 13 7 0,000 0,04891897 0,10979388 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04891897 0,10969156 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04891897 0,10958942 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04891897 0,10948748 ! adrenal gland development GO:0030325 17 7 0,000 0,04891897 0,10938573 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04891897 0,10928416 ! ovulation GO:0030728 9 7 0,000 0,04891897 0,10918278 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04891897 0,10908159 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04891897 0,10898059 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04891897 0,10887978 ! microtubule nucleation GO:0007020 20 7 0,000 0,04891897 0,10877915 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04891897 0,10867871 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04891897 0,10857845 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04891897 0,10847838 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04891897 0,10837849 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04891897 0,10827879 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04891897 0,10817927 ! galactose metabolic process GO:0006012 13 7 0,000 0,04891897 0,10807993 ! vesicle fusion GO:0006906 17 7 0,000 0,04891897 0,10798077 ! response to dietary excess GO:0002021 8 7 0,000 0,04891897 0,1078818 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04891897 0,107783 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04891897 0,10768439 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04891897 0,10758596 ! purine salvage GO:0043101 10 7 0,000 0,04891897 0,10748771 ! nucleoside transport GO:0015858 8 7 0,000 0,04891897 0,10738964 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04891897 0,10729174 ! parturition GO:0007567 14 7 0,000 0,04891897 0,10719403 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04891897 0,10709649 ! rRNA modification GO:0000154 14 7 0,000 0,04891897 0,10699913 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04891897 0,10690194 ! spindle checkpoint GO:0031577 15 7 0,000 0,04891897 0,10680494 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04891897 0,10670811 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04891897 0,10661145 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04891897 0,10651497 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04891897 0,10641866 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04891897 0,10632253 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04891897 0,10622657 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04891897 0,10613078 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04891897 0,10603517 ! eating behavior GO:0042755 7 7 0,000 0,04891897 0,10593973 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04891897 0,10584446 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04891897 0,10574936 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04891897 0,10565443 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04891897 0,10555968 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04891897 0,10546509 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04891897 0,10537067 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04891897 0,10527642 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04891897 0,10518234 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04891897 0,10508843 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04891897 0,10499468 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04891897 0,10490111 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04891897 0,10480769 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04891897 0,10471445 ! regulation of meiosis GO:0040020 12 7 0,000 0,04891897 0,10462137 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04891897 0,10452846 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04891897 0,10443571 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04891897 0,10434312 ! transcription termination GO:0006353 13 7 0,000 0,04891897 0,1042507 ! response to tumor cell GO:0002347 13 7 0,000 0,04891897 0,10415844 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04891897 0,10406635 ! anaphase GO:0051322 17 7 0,000 0,04891897 0,10397442 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04891897 0,10388265 ! axonal fasciculation GO:0007413 18 7 0,000 0,04891897 0,10379104 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04891897 0,1036996 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04891897 0,10360831 ! diuresis GO:0030146 12 7 0,000 0,04891897 0,10351719 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04891897 0,10342622 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04891897 0,10333542 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04891897 0,10324477 ! antibiotic transport GO:0042891 9 7 0,000 0,04891897 0,10315429 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04891897 0,10306396 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04891897 0,10297379 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04891897 0,10288378 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04891897 0,10279392 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04891897 0,10270422 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04891897 0,10261468 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04891897 0,1025253 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04891897 0,10243607 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04891897 0,10234699 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04891897 0,10225807 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04891897 0,10216931 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04891897 0,10208069 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04891897 0,10199224 ! adult feeding behavior GO:0008343 9 7 0,000 0,04891897 0,10190393 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04891897 0,10181578 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04891897 0,10172778 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04891897 0,10163993 ! muscle adaptation GO:0043500 14 7 0,000 0,04891897 0,10155223 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04891897 0,10146469 ! retina homeostasis GO:0001895 12 7 0,000 0,04891897 0,1013773 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04891897 0,10129005 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04891897 0,10120296 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04891897 0,10111601 ! protein prenylation GO:0018342 18 7 0,000 0,04891897 0,10102922 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04891897 0,10094257 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04891897 0,10085608 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04891897 0,10076973 ! neuromuscular process GO:0050905 99 50 1,000 0,04968103 0,10225197 ! regulation of ossification GO:0030278 117 50 1,000 0,04968103 0,10216458 ! inner ear development GO:0048839 79 50 1,000 0,04968103 0,10207733 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,04968103 0,10199023 ! positive regulation of binding GO:0051099 78 51 1,000 0,05147181 0,10557645 ! viral infectious cycle GO:0019058 99 51 1,000 0,05147181 0,10548653 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,05147181 0,10539675 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,05147181 0,10530713 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,05147181 0,10521766 ! vesicle organization GO:0016050 107 51 1,000 0,05147181 0,10512834 ! regulation of cell shape GO:0008360 125 51 1,000 0,05147181 0,10503917 ! synapse organization GO:0050808 85 52 1,000 0,05328547 0,10864818 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,05512159 0,11229683 ! regulation of translational initiation GO:0006446 82 53 1,000 0,05512159 0,11220182 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,05512159 0,11210698 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05571015 0,11320829 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05571015 0,11311276 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05571015 0,11301739 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05571015 0,11292217 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05571015 0,11282712 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05571015 0,11273223 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05571015 0,11263749 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,05571015 0,11254292 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05571015 0,11244851 ! meiotic prophase I GO:0007128 13 8 0,000 0,05571015 0,11235425 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05571015 0,11226015 ! oligopeptide transport GO:0006857 15 8 0,000 0,05571015 0,11216621 ! UTP metabolic process GO:0046051 8 8 0,000 0,05571015 0,11207242 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05571015 0,1119788 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05571015 0,11188532 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05571015 0,11179201 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05571015 0,11169885 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05571015 0,11160584 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05571015 0,11151299 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05571015 0,1114203 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05571015 0,11132776 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05571015 0,11123537 ! reflex GO:0060004 16 8 0,000 0,05571015 0,11114313 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05571015 0,11105105 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05571015 0,11095912 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05571015 0,11086734 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05571015 0,11077572 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,05571015 0,11068424 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05571015 0,11059292 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,05571015 0,11050175 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05571015 0,11041072 ! astrocyte differentiation GO:0048708 18 8 0,000 0,05571015 0,11031985 ! histidine metabolic process GO:0006547 16 8 0,000 0,05571015 0,11022913 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05571015 0,11013855 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05571015 0,11004813 ! glycine catabolic process GO:0006546 13 8 0,000 0,05571015 0,10995785 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05571015 0,10986772 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05571015 0,10977774 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05571015 0,1096879 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05571015 0,10959822 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05571015 0,10950868 ! macrophage activation GO:0042116 12 8 0,000 0,05571015 0,10941928 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05571015 0,10933003 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05571015 0,10924093 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05571015 0,10915197 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05571015 0,10906316 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05571015 0,10897449 ! osteoblast development GO:0002076 16 8 0,000 0,05571015 0,10888596 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05571015 0,10879758 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05571015 0,10870934 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,05571015 0,10862125 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05571015 0,10853329 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05571015 0,10844548 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05571015 0,10835782 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05571015 0,10827029 ! intermediate filament organization GO:0045109 12 8 0,000 0,05571015 0,1081829 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05571015 0,10809566 ! cellular extravasation GO:0045123 12 8 0,000 0,05571015 0,10800856 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05571015 0,10792159 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05571015 0,10783477 ! response to antibiotic GO:0046677 11 8 0,000 0,05571015 0,10774809 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05571015 0,10766154 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05571015 0,10757514 ! response to tropane GO:0014073 15 8 0,000 0,05571015 0,10748887 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05571015 0,10740274 ! melanosome transport GO:0032402 13 8 0,000 0,05571015 0,10731675 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05571015 0,1072309 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05571015 0,10714518 ! mast cell activation GO:0045576 14 8 0,000 0,05571015 0,1070596 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05571015 0,10697416 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05571015 0,10688885 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05571015 0,10680368 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05571015 0,10671865 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05571015 0,10663375 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05571015 0,10654898 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,05571015 0,10646435 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05571015 0,10637986 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05571015 0,10629549 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05571015 0,10621127 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05571015 0,10612717 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05571015 0,10604321 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05571015 0,10595938 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05571015 0,10587569 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05571015 0,10579212 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05571015 0,10570869 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05571015 0,10562539 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05571015 0,10554222 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05571015 0,10545918 ! hormone catabolic process GO:0042447 17 8 0,000 0,05571015 0,10537627 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05571015 0,10529349 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05571015 0,10521085 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05571015 0,10512833 ! ATP catabolic process GO:0006200 11 8 0,000 0,05571015 0,10504594 ! blastocyst growth GO:0001832 19 8 0,000 0,05571015 0,10496368 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05571015 0,10488155 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05571015 0,10479955 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05571015 0,10471767 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05571015 0,10463592 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05571015 0,1045543 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05571015 0,10447281 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05571015 0,10439145 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05571015 0,10431021 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05571015 0,1042291 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05571015 0,10414811 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05571015 0,10406725 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05571015 0,10398652 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05571015 0,10390591 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05571015 0,10382542 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05571015 0,10374506 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05571015 0,10366483 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,05697977 0,10594538 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,05697977 0,10586357 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,05885958 0,10927173 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,05885958 0,10918748 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,06076065 0,11262721 ! axon extension GO:0048675 15 9 0,000 0,06245306 0,11567518 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,06245306 0,1155862 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,06245306 0,11549736 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,06245306 0,11540865 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06245306 0,11532008 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,06245306 0,11523164 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,06245306 0,11514334 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,06245306 0,11505518 ! phosphate transport GO:0006817 19 9 0,000 0,06245306 0,11496715 ! reproductive behavior GO:0019098 19 9 0,000 0,06245306 0,11487925 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06245306 0,11479149 ! CTP metabolic process GO:0046036 9 9 0,000 0,06245306 0,11470387 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,06245306 0,11461637 ! GTP metabolic process GO:0046039 9 9 0,000 0,06245306 0,11452901 ! RNA methylation GO:0001510 15 9 0,000 0,06245306 0,11444178 ! elastic fiber assembly GO:0048251 15 9 0,000 0,06245306 0,11435469 ! artery development GO:0060840 24 9 0,000 0,06245306 0,11426773 GO:0048844|artery morphogenesis, ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,06245306 0,1141809 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,06245306 0,1140942 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,06245306 0,11400764 ! chemosensory behavior GO:0007635 20 9 0,000 0,06245306 0,1139212 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,06245306 0,1138349 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06245306 0,11374872 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,06245306 0,11366268 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,06245306 0,11357677 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,06245306 0,11349098 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06245306 0,11340533 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06245306 0,11331981 ! protein targeting to ER GO:0045047 22 9 0,000 0,06245306 0,11323441 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,06245306 0,11314914 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,06245306 0,11306401 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,06245306 0,112979 ! endosome organization GO:0007032 17 9 0,000 0,06245306 0,11289411 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06245306 0,11280936 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06245306 0,11272473 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06245306 0,11264023 ! mannose metabolic process GO:0006013 13 9 0,000 0,06245306 0,11255585 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,06245306 0,1124716 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,06245306 0,11238748 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,06245306 0,11230349 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,06245306 0,11221961 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06245306 0,11213587 ! ruffle organization GO:0031529 15 9 0,000 0,06245306 0,11205225 ! retinol metabolic process GO:0042572 18 9 0,000 0,06245306 0,11196875 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,06245306 0,11188538 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,06245306 0,11180213 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,06245306 0,11171901 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,06245306 0,11163601 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,06245306 0,11155313 ! oligodendrocyte development GO:0014003 10 9 0,000 0,06245306 0,11147037 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06245306 0,11138774 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,06245306 0,11130523 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06245306 0,11122284 ! response to amine stimulus GO:0014075 13 9 0,000 0,06245306 0,11114058 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,06245306 0,11105844 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,06245306 0,11097641 ! erythrocyte development GO:0048821 15 9 0,000 0,06245306 0,11089451 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,06245306 0,11081273 ! renal water homeostasis GO:0003091 14 9 0,000 0,06245306 0,11073107 ! postreplication repair GO:0006301 22 9 0,000 0,06245306 0,11064953 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,06245306 0,11056811 ! icosanoid secretion GO:0032309 15 9 0,000 0,06245306 0,11048681 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,06245306 0,11040563 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06245306 0,11032457 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,06245306 0,11024363 ! regulation of cell division GO:0051302 15 9 0,000 0,06245306 0,1101628 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,06245306 0,1100821 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,06245306 0,11000151 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,06245306 0,10992104 ! sterol catabolic process GO:0016127 11 9 0,000 0,06245306 0,10984069 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06245306 0,10976046 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,06245306 0,10968034 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,06245306 0,10960034 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,06245306 0,10952045 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 0,000 0,06245306 0,10944069 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,06245306 0,10936104 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,06245306 0,1092815 ! purine base metabolic process GO:0006144 21 9 0,000 0,06245306 0,10920208 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,06245306 0,10912278 ! pigment granule transport GO:0051904 17 9 0,000 0,06245306 0,10904359 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,06245306 0,10896451 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,06245306 0,10888555 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06245306 0,10880671 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06245306 0,10872798 ! mitochondrion localization GO:0051646 15 9 0,000 0,06245306 0,10864936 ! muscle fiber development GO:0048747 112 57 1,000 0,06268256 0,10896983 ! lipid modification GO:0030258 97 57 1,000 0,06268256 0,10889115 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,06268256 0,10881259 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,06268256 0,10873413 ! maintenance of location GO:0051235 118 57 1,000 0,06268256 0,1086558 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,06462493 0,11194211 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,06658738 0,11525844 ! establishment of organelle localization GO:0051656 109 59 1,000 0,06658738 0,11517558 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,06856951 0,11851885 ! regulation of heart contraction GO:0008016 110 60 1,000 0,06856951 0,11843377 ! camera-type eye development GO:0043010 116 60 1,000 0,06856951 0,11834881 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06914804 0,11926179 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06914804 0,11917636 ! synapsis GO:0007129 13 10 0,000 0,06914804 0,11909105 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06914804 0,11900586 ! N-glycan processing GO:0006491 20 10 0,000 0,06914804 0,1189208 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06914804 0,11883585 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06914804 0,11875103 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06914804 0,11866633 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06914804 0,11858175 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06914804 0,11849729 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06914804 0,11841295 ! androgen metabolic process GO:0008209 17 10 0,000 0,06914804 0,11832873 ! phospholipid efflux GO:0033700 16 10 0,000 0,06914804 0,11824463 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06914804 0,11816065 ! pathogenesis GO:0009405 13 10 0,000 0,06914804 0,11807679 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06914804 0,11799305 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06914804 0,11790942 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06914804 0,11782592 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06914804 0,11774253 ! endoderm development GO:0007492 16 10 0,000 0,06914804 0,11765926 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06914804 0,11757611 ! arginine catabolic process GO:0006527 13 10 0,000 0,06914804 0,11749308 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06914804 0,11741016 ! proline metabolic process GO:0006560 13 10 0,000 0,06914804 0,11732736 ! L-serine metabolic process GO:0006563 18 10 0,000 0,06914804 0,11724468 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06914804 0,11716211 ! V(D)J recombination GO:0033151 28 10 0,000 0,06914804 0,11707966 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06914804 0,11699732 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06914804 0,11691511 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06914804 0,116833 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06914804 0,11675101 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06914804 0,11666914 ! multicellular organism growth GO:0035264 18 10 0,000 0,06914804 0,11658738 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06914804 0,11650574 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06914804 0,11642421 ! epithelial cell development GO:0002064 20 10 0,000 0,06914804 0,11634279 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06914804 0,11626149 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06914804 0,1161803 ! macroautophagy GO:0016236 17 10 0,000 0,06914804 0,11609923 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06914804 0,11601827 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06914804 0,11593742 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06914804 0,11585668 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06914804 0,11577606 ! brain morphogenesis GO:0048854 23 10 0,000 0,06914804 0,11569555 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06914804 0,11561515 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06914804 0,11553486 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06914804 0,11545468 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06914804 0,11537462 ! response to dsRNA GO:0043331 20 10 0,000 0,06914804 0,11529466 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06914804 0,11521482 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06914804 0,11513508 ! melanosome localization GO:0032400 16 10 0,000 0,06914804 0,11505546 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06914804 0,11497595 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06914804 0,11489654 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06914804 0,11481725 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06914804 0,11473807 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06914804 0,11465899 ! mRNA cleavage GO:0006379 17 10 0,000 0,06914804 0,11458002 ! protein sumoylation GO:0016925 15 10 0,000 0,06914804 0,11450117 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06914804 0,11442242 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06914804 0,11434378 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06914804 0,11426524 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06914804 0,11418682 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06914804 0,1141085 ! salivary gland development GO:0007431 27 10 0,000 0,06914804 0,11403029 ! prophase GO:0051324 15 10 0,000 0,06914804 0,11395219 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06914804 0,11387419 ! apical protein localization GO:0045176 15 10 0,000 0,06914804 0,1137963 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06914804 0,11371852 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06914804 0,11364084 ! midbrain development GO:0030901 13 10 0,000 0,06914804 0,11356327 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06914804 0,11348581 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06914804 0,11340845 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06914804 0,1133312 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06914804 0,11325405 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06914804 0,113177 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06914804 0,11310007 ! detection of calcium ion GO:0005513 23 10 0,000 0,06914804 0,11302323 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06914804 0,1129465 ! blastocyst formation GO:0001825 17 10 0,000 0,06914804 0,11286988 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06914804 0,11279335 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06914804 0,11271694 ! activation of innate immune response GO:0002218 12 10 0,000 0,06914804 0,11264062 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06914804 0,11256441 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06914804 0,1124883 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06914804 0,11241229 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06914804 0,11233639 ! detection of external stimulus GO:0009581 91 63 1,000 0,07463028 0,1211609 ! respiratory burst GO:0045730 17 11 0,000 0,07579544 0,12296954 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,07579544 0,12288668 ! telencephalon cell migration GO:0022029 20 11 0,000 0,07579544 0,12280393 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,07579544 0,12272129 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,07579544 0,12263876 ! thyroid gland development GO:0030878 26 11 0,000 0,07579544 0,12255634 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,07579544 0,12247403 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,07579544 0,12239183 ! response to pain GO:0048265 24 11 0,000 0,07579544 0,12230975 ! T cell proliferation GO:0042098 26 11 0,000 0,07579544 0,12222777 ! bone resorption GO:0045453 16 11 0,000 0,07579544 0,1221459 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07579544 0,12206414 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07579544 0,1219825 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,07579544 0,12190096 ! melanocyte differentiation GO:0030318 21 11 0,000 0,07579544 0,12181953 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,07579544 0,12173821 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,07579544 0,12165699 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,07579544 0,12157589 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,07579544 0,12149489 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,07579544 0,121414 ! lipid digestion GO:0044241 18 11 0,000 0,07579544 0,12133322 ! UV protection GO:0009650 19 11 0,000 0,07579544 0,12125255 ! adult heart development GO:0007512 14 11 0,000 0,07579544 0,12117198 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,07579544 0,12109152 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07579544 0,12101117 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,07579544 0,12093092 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,07579544 0,12085078 ! regulation of organ growth GO:0046620 13 11 0,000 0,07579544 0,12077075 ! pigment granule localization GO:0051875 20 11 0,000 0,07579544 0,12069082 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,07579544 0,120611 ! vasoconstriction GO:0042310 18 11 0,000 0,07579544 0,12053128 ! embryonic axis specification GO:0000578 18 11 0,000 0,07579544 0,12045167 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,07579544 0,12037217 ! snRNA metabolic process GO:0016073 24 11 0,000 0,07579544 0,12029277 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07579544 0,12021347 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,07579544 0,12013428 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,07579544 0,12005519 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,07579544 0,11997621 ! zymogen activation GO:0031638 15 11 0,000 0,07579544 0,11989733 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,07579544 0,11981855 ! nucleosome positioning GO:0016584 15 11 0,000 0,07579544 0,11973988 ! regulation of isotype switching GO:0045191 22 11 0,000 0,07579544 0,11966131 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,07579544 0,11958284 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,07579544 0,11950448 ! acid secretion GO:0046717 18 11 0,000 0,07579544 0,11942622 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07579544 0,11934806 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,07579544 0,11927 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,07579544 0,11919205 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,07579544 0,11911419 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,07579544 0,11903644 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,07579544 0,11895879 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,07579544 0,11888125 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07579544 0,1188038 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,07579544 0,11872645 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,07579544 0,11864921 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,07579544 0,11857206 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,07579544 0,11849502 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,07579544 0,11841807 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,07579544 0,11834123 ! defense response to fungus GO:0050832 13 11 0,000 0,07579544 0,11826448 ! developmental induction GO:0031128 19 11 0,000 0,07579544 0,11818784 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,07579544 0,11811129 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07579544 0,11803484 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,07579544 0,11795849 ! sequestering of metal ion GO:0051238 14 11 0,000 0,07579544 0,11788224 ! lamellipodium assembly GO:0030032 20 11 0,000 0,07579544 0,11780609 ! nucleus localization GO:0051647 19 11 0,000 0,07579544 0,11773004 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,07668743 0,11903869 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,07668743 0,11896194 GO:0048609|reproductive process in a multicellular organism, ! cell projection assembly GO:0030031 120 66 1,000 0,0808549 0,12534594 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,08239559 0,12765215 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,08239559 0,12757 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,08239559 0,12748796 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,08239559 0,12740603 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,08239559 0,1273242 ! mating GO:0007618 17 12 0,000 0,08239559 0,12724248 ! protein complex disassembly GO:0043241 27 12 0,000 0,08239559 0,12716086 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,08239559 0,12707935 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,08239559 0,12699794 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,08239559 0,12691663 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,08239559 0,12683543 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,08239559 0,12675434 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,08239559 0,12667334 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,08239559 0,12659245 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,08239559 0,12651167 ! drug transport GO:0015893 16 12 0,000 0,08239559 0,12643098 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,08239559 0,1263504 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,08239559 0,12626993 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,08239559 0,12618955 ! polyamine metabolic process GO:0006595 17 12 0,000 0,08239559 0,12610928 ! mitotic spindle organization GO:0007052 21 12 0,000 0,08239559 0,12602911 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,08239559 0,12594904 ! forebrain cell migration GO:0021885 21 12 0,000 0,08239559 0,12586907 ! asymmetric protein localization GO:0008105 20 12 0,000 0,08239559 0,1257892 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,08239559 0,12570944 ! entry into host cell GO:0030260 32 12 0,000 0,08239559 0,12562977 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,08239559 0,12555021 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08239559 0,12547075 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,08239559 0,12539139 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,08239559 0,12531213 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,08239559 0,12523296 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,08239559 0,1251539 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,08239559 0,12507494 ! protein homotetramerization GO:0051289 21 12 0,000 0,08239559 0,12499608 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,08239559 0,12491732 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,08239559 0,12483865 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08239559 0,12476009 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,08239559 0,12468162 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,08239559 0,12460326 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,08239559 0,12452499 ! cranial nerve development GO:0021545 20 12 0,000 0,08239559 0,12444682 ! fucose catabolic process GO:0019317 22 12 0,000 0,08239559 0,12436875 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,08239559 0,12429077 ! histone methylation GO:0016571 26 12 0,000 0,08239559 0,1242129 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,08239559 0,12413512 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,08239559 0,12405744 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,08239559 0,12397985 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,08239559 0,12390236 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,08239559 0,12382497 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,08239559 0,12374768 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,08239559 0,12367048 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,08239559 0,12359338 ! response to cold GO:0009409 17 12 0,000 0,08239559 0,12351638 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,08239559 0,12343947 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,08296451 0,12421445 ! adaptive immune response GO:0002250 119 67 1,000 0,08296451 0,1241372 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,08509091 0,12723973 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,08509091 0,1271607 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08894882 0,13284348 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08894882 0,13276107 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08894882 0,13267877 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,08894882 0,13259656 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08894882 0,13251446 ! lipid localization GO:0010876 28 13 0,000 0,08894882 0,13243246 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,08894882 0,13235056 ! organelle fusion GO:0048284 32 13 0,000 0,08894882 0,13226876 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,08894882 0,13218706 ! endocrine pancreas development GO:0031018 22 13 0,000 0,08894882 0,13210546 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08894882 0,13202397 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,08894882 0,13194257 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08894882 0,13186128 ! methionine metabolic process GO:0006555 27 13 0,000 0,08894882 0,13178008 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,08894882 0,13169898 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08894882 0,13161799 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,08894882 0,13153709 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,08894882 0,1314563 ! response to X-ray GO:0010165 25 13 0,000 0,08894882 0,1313756 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,08894882 0,131295 ! exocrine system development GO:0035272 32 13 0,000 0,08894882 0,1312145 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08894882 0,1311341 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08894882 0,1310538 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,08894882 0,13097359 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,08894882 0,13089349 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,08894882 0,13081348 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,08894882 0,13073357 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,08894882 0,13065375 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08894882 0,13057404 ! regulation of cellular pH GO:0030641 22 13 0,000 0,08894882 0,13049442 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08894882 0,1304149 ! ribosome assembly GO:0042255 17 13 0,000 0,08894882 0,13033548 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08894882 0,13025615 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08894882 0,13017692 ! chromatin silencing GO:0006342 26 13 0,000 0,08894882 0,13009778 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,08894882 0,13001874 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08894882 0,1299398 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08894882 0,12986095 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,08894882 0,1297822 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08894882 0,12970355 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08894882 0,12962499 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08894882 0,12954652 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,08894882 0,12946815 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08894882 0,12938987 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,08894882 0,12931169 ! insulin secretion GO:0030073 23 13 0,000 0,08894882 0,12923361 ! actin filament polymerization GO:0030041 24 13 0,000 0,08894882 0,12915561 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,08894882 0,12907771 ! acrosome reaction GO:0007340 18 13 0,000 0,08894882 0,12899991 ! humoral immune response GO:0006959 109 71 1,000 0,09156737 0,13271752 ! B cell activation GO:0042113 160 71 1,000 0,09156737 0,13263762 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,09156737 0,13255782 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,09375749 0,13564674 ! rRNA transcription GO:0009303 25 14 0,000 0,09545546 0,13802033 ! lactation GO:0007595 26 14 0,000 0,09545546 0,13793744 ! reproductive cellular process GO:0048610 20 14 0,000 0,09545546 0,13785464 ! tRNA modification GO:0006400 20 14 0,000 0,09545546 0,13777195 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,09545546 0,13768935 ! regulation of S phase GO:0033261 23 14 0,000 0,09545546 0,13760685 ! water transport GO:0006833 21 14 0,000 0,09545546 0,13752445 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,09545546 0,13744215 ! non-recombinational repair GO:0000726 25 14 0,000 0,09545546 0,13735995 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,09545546 0,13727785 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,09545546 0,13719584 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,09545546 0,13711393 ! RNA polyadenylation GO:0043631 30 14 0,000 0,09545546 0,13703212 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,09545546 0,13695041 ! palate development GO:0060021 31 14 0,000 0,09545546 0,13686879 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,09545546 0,13678728 ! regulated secretory pathway GO:0045055 23 14 0,000 0,09545546 0,13670585 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,09545546 0,13662453 ! arginine metabolic process GO:0006525 17 14 0,000 0,09545546 0,1365433 ! regulation of heart rate GO:0002027 24 14 0,000 0,09545546 0,13646217 ! organic alcohol transport GO:0015850 29 14 0,000 0,09545546 0,13638114 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,09545546 0,1363002 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,09545546 0,13621936 ! neutral amino acid transport GO:0015804 26 14 0,000 0,09545546 0,13613861 ! L-amino acid transport GO:0015807 30 14 0,000 0,09545546 0,13605796 ! bone mineralization GO:0030282 17 14 0,000 0,09545546 0,1359774 ! stem cell development GO:0048864 43 14 0,000 0,09545546 0,13589694 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,09545546 0,13581658 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09545546 0,13573631 ! cerebellum development GO:0021549 21 14 0,000 0,09545546 0,13565613 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,09545546 0,13557605 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,09545546 0,13549607 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,09545546 0,13541618 ! cofactor transport GO:0051181 26 14 0,000 0,09545546 0,13533638 ! NADP metabolic process GO:0006739 24 14 0,000 0,09545546 0,13525668 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,09545546 0,13517707 ! intestinal absorption GO:0050892 25 14 0,000 0,09545546 0,13509755 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,09545546 0,13501813 ! oxygen transport GO:0015671 21 14 0,000 0,09545546 0,1349388 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,09545546 0,13485956 ! male genitalia development GO:0030539 24 14 0,000 0,09545546 0,13478042 ! regulation of axon extension GO:0030516 37 14 0,000 0,09545546 0,13470137 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,09545546 0,13462241 ! learning or memory GO:0007611 147 73 1,000 0,09596272 0,13525853 ! regulation of blood pressure GO:0008217 125 73 1,000 0,09596272 0,13517934 ! meiosis GO:0007126 121 74 1,000 0,09818273 0,13822565 GO:0051327|M phase of meiotic cell cycle, ! organelle localization GO:0051640 136 74 1,000 0,09818273 0,13814482 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,10041719 0,14120617 ! meiotic cell cycle GO:0051321 122 75 1,000 0,10041719 0,14112368 ! rhythmic process GO:0048511 128 75 1,000 0,10041719 0,1410413 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,10191585 0,14306274 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,10191585 0,14297932 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,10191585 0,142896 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,10191585 0,14281277 ! copper ion transport GO:0006825 20 15 0,000 0,10191585 0,14272965 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,10191585 0,14264661 ! sulfate transport GO:0008272 23 15 0,000 0,10191585 0,14256368 ! response to cAMP GO:0051591 22 15 0,000 0,10191585 0,14248084 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,10191585 0,1423981 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,10191585 0,14231546 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,10191585 0,14223291 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,10191585 0,14215045 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,10191585 0,14206809 ! response to hexose stimulus GO:0009746 22 15 0,000 0,10191585 0,14198583 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,10191585 0,14190366 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,10191585 0,14182159 ! pituitary gland development GO:0021983 29 15 0,000 0,10191585 0,14173961 ! vesicle coating GO:0006901 33 15 0,000 0,10191585 0,14165773 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,10191585 0,14157594 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,10191585 0,14149425 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,10191585 0,14141265 ! regulation of exocytosis GO:0017157 22 15 0,000 0,10191585 0,14133114 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,10191585 0,14124973 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,10191585 0,14116841 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,10191585 0,14108719 ! regulation of vasodilation GO:0042312 26 15 0,000 0,10191585 0,14100606 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,10191585 0,14092502 ! histone deacetylation GO:0016575 20 15 0,000 0,10191585 0,14084407 ! tissue regeneration GO:0042246 26 15 0,000 0,10191585 0,14076322 ! water homeostasis GO:0030104 27 15 0,000 0,10191585 0,14068246 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,10191585 0,14060179 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,10191585 0,14052122 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,10191585 0,14044074 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,10191585 0,14036035 ! dopamine metabolic process GO:0042417 35 15 0,000 0,10191585 0,14028005 ! cell killing GO:0001906 29 15 0,000 0,10191585 0,14019985 ! detection of bacterium GO:0016045 18 15 0,000 0,10191585 0,14011973 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,10191585 0,14003971 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,10191585 0,13995978 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,10191585 0,13987994 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,10492821 0,14393231 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,10720415 0,14697047 ! protein oligomerization GO:0051259 139 78 1,000 0,10720415 0,14688678 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,10833031 0,14834532 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,10833031 0,14826093 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,10833031 0,14817665 ! bone remodeling GO:0046849 27 16 0,000 0,10833031 0,14809246 ! filopodium assembly GO:0046847 32 16 0,000 0,10833031 0,14800836 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,10833031 0,14792436 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,10833031 0,14784046 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,10833031 0,14775665 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,10833031 0,14767293 ! startle response GO:0001964 28 16 0,000 0,10833031 0,14758931 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,10833031 0,14750579 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,10833031 0,14742235 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,10833031 0,14733902 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,10833031 0,14725578 ! protein polyubiquitination GO:0000209 34 16 0,000 0,10833031 0,14717263 ! glutamate metabolic process GO:0006536 22 16 0,000 0,10833031 0,14708957 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,10833031 0,14700661 ! response to osmotic stress GO:0006970 25 16 0,000 0,10833031 0,14692374 ! lysosomal transport GO:0007041 26 16 0,000 0,10833031 0,14684097 ! fructose metabolic process GO:0006000 25 16 0,000 0,10833031 0,14675829 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10833031 0,1466757 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10833031 0,14659321 ! intermediate filament-based process GO:0045103 32 16 0,000 0,10833031 0,14651081 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,10833031 0,1464285 ! negative regulation of immune response GO:0050777 35 16 0,000 0,10833031 0,14634628 ! axon cargo transport GO:0008088 43 16 0,000 0,10833031 0,14626415 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,10833031 0,14618212 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,10833031 0,14610018 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,10833031 0,14601833 ! DNA replication initiation GO:0006270 27 16 0,000 0,10833031 0,14593657 ! neuron recognition GO:0008038 35 16 0,000 0,10833031 0,14585491 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,10833031 0,14577333 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,10833031 0,14569185 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,10833031 0,14561046 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,10833031 0,14552916 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,10833031 0,14544795 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,10833031 0,14536683 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,10833031 0,1452858 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10833031 0,14520486 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,10833031 0,14512401 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,10833031 0,14504325 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,10833031 0,14496258 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,1094933 0,1464374 ! muscle cell differentiation GO:0042692 159 80 1,000 0,11179536 0,14943312 ! protein import into nucleus GO:0006606 158 80 1,000 0,11179536 0,14935015 ! digestion GO:0007586 112 81 1,000 0,11411002 0,15235778 ! nuclear import GO:0051170 161 81 1,000 0,11411002 0,15227327 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,11469917 0,15297461 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,11469917 0,15288986 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,11469917 0,1528052 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,11469917 0,15272064 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,11469917 0,15263617 ! endothelial cell migration GO:0043542 28 17 0,000 0,11469917 0,15255179 ! inositol metabolic process GO:0006020 28 17 0,000 0,11469917 0,15246751 ! gene silencing by RNA GO:0031047 36 17 0,000 0,11469917 0,15238332 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,11469917 0,15229922 ! glial cell development GO:0021782 27 17 0,000 0,11469917 0,15221522 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,11469917 0,15213131 ! adult walking behavior GO:0007628 33 17 0,000 0,11469917 0,15204749 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,11469917 0,15196376 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,11469917 0,15188013 ! myoblast differentiation GO:0045445 45 17 0,000 0,11469917 0,15179659 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,11469917 0,15171314 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,11469917 0,15162978 ! glycine metabolic process GO:0006544 28 17 0,000 0,11469917 0,15154651 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,11469917 0,15146333 ! NAD metabolic process GO:0019674 29 17 0,000 0,11469917 0,15138025 ! membrane budding GO:0006900 37 17 0,000 0,11469917 0,15129726 ! DNA integration GO:0015074 29 17 0,000 0,11469917 0,15121435 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,11469917 0,15113154 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,11469917 0,15104882 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,11469917 0,15096619 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,11469917 0,15088365 ! genitalia development GO:0048806 30 17 0,000 0,11469917 0,1508012 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,11469917 0,15071884 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,11469917 0,15063657 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,11469917 0,15055439 ! steroid catabolic process GO:0006706 31 17 0,000 0,11469917 0,1504723 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,11469917 0,1503903 ! gas transport GO:0015669 25 17 0,000 0,11469917 0,15030838 ! organic cation transport GO:0015695 31 17 0,000 0,11469917 0,15022656 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,11469917 0,15014483 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,11469917 0,15006318 ! microspike assembly GO:0030035 36 17 0,000 0,11469917 0,14998163 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,11469917 0,14990016 ! response to nutrient GO:0007584 125 82 1,000 0,116437 0,15208872 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,12102274 0,1579928 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,12102274 0,15790712 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,12102274 0,15782153 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,12102274 0,15773604 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,12102274 0,15765063 ! memory GO:0007613 31 18 0,000 0,12102274 0,15756533 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,12102274 0,15748011 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,12102274 0,15739498 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,12102274 0,15730995 ! glutamine metabolic process GO:0006541 29 18 0,000 0,12102274 0,15722501 ! response to retinoic acid GO:0032526 26 18 0,000 0,12102274 0,15714016 ! response to fungus GO:0009620 21 18 0,000 0,12102274 0,15705541 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,12102274 0,15697074 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,12102274 0,15688616 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,12102274 0,15680168 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,12102274 0,15671729 ! vitamin transport GO:0051180 27 18 0,000 0,12102274 0,15663299 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,12102274 0,15654877 ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,12102274 0,15646465 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,12102274 0,15638062 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,12102274 0,15629668 ! nerve development GO:0021675 28 18 0,000 0,12102274 0,15621283 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,12102274 0,15612907 ! negative regulation of transport GO:0051051 153 84 1,000 0,12112674 0,15617949 ! response to unfolded protein GO:0006986 131 85 1,000 0,12348892 0,15913999 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,12348892 0,15905479 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of translation GO:0045727 30 19 0,000 0,12730136 0,16387751 ! negative regulation of defense response GO:0031348 25 19 0,000 0,12730136 0,16378988 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,12730136 0,16370234 ! skin development GO:0043588 36 19 0,000 0,12730136 0,16361489 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,12730136 0,16352754 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,12730136 0,16344027 ! bile acid metabolic process GO:0008206 29 19 0,000 0,12730136 0,16335311 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,12730136 0,16326603 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,12730136 0,16317905 ! cerebral cortex development GO:0021987 36 19 0,000 0,12730136 0,16309216 ! response to vitamin A GO:0033189 27 19 0,000 0,12730136 0,16300536 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,12730136 0,16291866 ! plasma membrane fusion GO:0045026 28 19 0,000 0,12730136 0,16283204 ! peptide cross-linking GO:0018149 37 19 0,000 0,12730136 0,16274552 ! protein export from nucleus GO:0006611 36 19 0,000 0,12730136 0,16265909 ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,12730136 0,16257276 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,12730136 0,16248651 ! visual learning GO:0008542 36 19 0,000 0,12730136 0,16240036 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,12730136 0,1623143 ! cell-cell junction organization GO:0045216 35 19 0,000 0,12730136 0,16222832 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,12730136 0,16214244 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,12730136 0,16205665 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,12730136 0,16197095 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,12730136 0,16188535 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,12730136 0,16179983 ! cilium assembly GO:0042384 37 19 0,000 0,12730136 0,1617144 ! peptide hormone secretion GO:0030072 31 19 0,000 0,12730136 0,16162906 ! cellular respiration GO:0045333 135 88 1,000 0,13064138 0,16578226 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,13304659 0,16874543 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,13353534 0,16927609 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,13353534 0,16918695 ! positive regulation of ossification GO:0045778 47 20 0,000 0,13353534 0,16909791 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,13353534 0,16900895 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,13353534 0,1689201 ! cAMP metabolic process GO:0046058 36 20 0,000 0,13353534 0,16883133 ! response to vitamin GO:0033273 31 20 0,000 0,13353534 0,16874266 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,13353534 0,16865408 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,13353534 0,16856559 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,13353534 0,1684772 ! retinoid metabolic process GO:0001523 32 20 0,000 0,13353534 0,1683889 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,13353534 0,16830069 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,13353534 0,16821258 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,13353534 0,16812455 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,13353534 0,16803662 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,13353534 0,16794878 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,13353534 0,16786104 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,13353534 0,16777338 ! body fluid secretion GO:0007589 31 20 0,000 0,13353534 0,16768581 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,13353534 0,16759834 ! peptide secretion GO:0002790 35 20 0,000 0,13353534 0,16751096 ! stem cell differentiation GO:0048863 53 20 0,000 0,13353534 0,16742367 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,13353534 0,16733647 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,13353534 0,16724936 ! sensory perception of pain GO:0019233 30 20 0,000 0,13353534 0,16716234 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,13353534 0,16707541 ! diencephalon development GO:0021536 34 20 0,000 0,13353534 0,16698858 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,13353534 0,16690183 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,13353534 0,16681517 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,13353534 0,1667286 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,13353534 0,16664213 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,13353534 0,16655574 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,13353534 0,16646944 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,13353534 0,16638323 ! regulation of glucose import GO:0046324 29 20 0,000 0,13353534 0,16629711 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,13353534 0,16621108 ! actin filament-based movement GO:0030048 43 20 0,000 0,13353534 0,16612514 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,13353534 0,16603929 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,13353534 0,16595352 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,13353534 0,16586785 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,13788696 0,17118474 ! regulation of cell killing GO:0031341 42 21 0,000 0,13972499 0,17337716 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,13972499 0,17328779 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,13972499 0,17319852 ! hormone secretion GO:0046879 38 21 0,000 0,13972499 0,17310933 ! glycerol metabolic process GO:0006071 34 21 0,000 0,13972499 0,17302024 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,13972499 0,17293123 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,13972499 0,17284232 ! axis specification GO:0009798 38 21 0,000 0,13972499 0,1727535 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,13972499 0,17266478 ! smooth muscle contraction GO:0006939 46 21 0,000 0,13972499 0,17257614 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,13972499 0,17248759 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,13972499 0,17239914 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,13972499 0,17231077 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,13972499 0,1722225 ! cytolysis GO:0019835 24 21 0,000 0,13972499 0,17213432 ! vasodilation GO:0042311 39 21 0,000 0,13972499 0,17204622 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,13972499 0,17195822 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,13972499 0,17187031 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,13972499 0,17178248 ! DNA modification GO:0006304 34 21 0,000 0,13972499 0,17169475 ! collagen fibril organization GO:0030199 59 21 0,000 0,13972499 0,17160711 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,13972499 0,17151955 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,13972499 0,17143209 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,13972499 0,17134471 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,13972499 0,17125742 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,13972499 0,17117022 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,13972499 0,17108311 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,13972499 0,17099609 ! collagen catabolic process GO:0030574 28 21 0,000 0,13972499 0,17090916 ! sperm-egg recognition GO:0035036 21 21 0,000 0,13972499 0,17082232 ! regulation of defense response GO:0031347 149 92 1,000 0,14032161 0,1714646 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,14276555 0,17436239 ! regulation of membrane potential GO:0042391 164 93 1,000 0,14276555 0,17427392 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,14587063 0,177974 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,14587063 0,17788379 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,14587063 0,17779368 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,14587063 0,17770366 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,14587063 0,17761373 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,14587063 0,17752389 ! keratinization GO:0031424 28 22 0,000 0,14587063 0,17743414 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,14587063 0,17734448 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,14587063 0,17725491 ! sensory perception of taste GO:0050909 28 22 0,000 0,14587063 0,17716543 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,14587063 0,17707605 ! vacuolar transport GO:0007034 36 22 0,000 0,14587063 0,17698675 ! lysosome organization GO:0007040 41 22 0,000 0,14587063 0,17689754 ! central nervous system neuron development GO:0021954 46 22 0,000 0,14587063 0,17680843 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,14587063 0,1767194 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,14587063 0,17663046 ! fucose metabolic process GO:0006004 39 22 0,000 0,14587063 0,17654161 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,14587063 0,17645285 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,14587063 0,17636418 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,14587063 0,1762756 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,14587063 0,17618711 ! sarcomere organization GO:0045214 30 22 0,000 0,14587063 0,17609871 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,14587063 0,17601039 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,14587063 0,17592217 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,14587063 0,17583403 ! detection of stimulus GO:0051606 151 96 1,000 0,15015058 0,18090251 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,15197256 0,183006 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,15197256 0,18291445 ! gluconeogenesis GO:0006094 33 23 0,000 0,15197256 0,18282299 ! viral genome replication GO:0019079 41 23 0,000 0,15197256 0,18273163 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,15197256 0,18264035 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,15197256 0,18254917 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,15197256 0,18245808 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,15197256 0,18236708 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,15197256 0,18227617 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,15197256 0,18218534 ! visual behavior GO:0007632 42 23 0,000 0,15197256 0,18209462 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,15197256 0,18200398 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,15197256 0,18191343 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,15197256 0,18182297 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,15197256 0,1817326 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,15197256 0,18164232 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,15197256 0,18155213 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,15197256 0,18146203 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,15197256 0,18137202 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,15197256 0,1812821 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,15197256 0,18119226 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,15197256 0,18110252 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,15197256 0,18101286 ! fatty acid transport GO:0015908 44 23 0,000 0,15197256 0,1809233 ! platelet activation GO:0030168 37 23 0,000 0,15197256 0,18083382 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,15197256 0,18074443 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,15197256 0,18065513 ! hormone transport GO:0009914 40 23 0,000 0,15197256 0,18056592 ! cell-cell recognition GO:0009988 25 23 0,000 0,15197256 0,1804768 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,15197256 0,18038776 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,15197256 0,18029881 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,15197256 0,18020995 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,15197256 0,18012118 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,15197256 0,18003249 ! protein ubiquitination GO:0016567 217 97 1,000 0,15262917 0,18072136 ! hormone metabolic process GO:0042445 157 97 1,000 0,15262917 0,18063246 ! response to virus GO:0009615 160 98 1,000 0,15511582 0,18348508 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,15803111 0,1868417 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,15803111 0,18674993 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,15803111 0,18665825 ! vesicle docking GO:0048278 47 24 0,000 0,15803111 0,18656666 ! vacuole organization GO:0007033 43 24 0,000 0,15803111 0,18647516 ! digestive system process GO:0022600 39 24 0,000 0,15803111 0,18638375 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,15803111 0,18629243 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,15803111 0,1862012 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,15803111 0,18611006 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,15803111 0,18601901 ! membrane depolarization GO:0051899 39 24 0,000 0,15803111 0,18592804 ! pentose metabolic process GO:0019321 35 24 0,000 0,15803111 0,18583717 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,15803111 0,18574639 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,15803111 0,18565569 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,15803111 0,18556508 ! alditol metabolic process GO:0019400 38 24 0,000 0,15803111 0,18547456 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,15803111 0,18538413 ! regulation of amine transport GO:0051952 40 24 0,000 0,15803111 0,18529379 ! myelination GO:0042552 45 25 0,000 0,16404657 0,19225331 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,16404657 0,19215971 ! phototransduction GO:0007602 33 25 0,000 0,16404657 0,19206621 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,16404657 0,19197279 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,16404657 0,19187946 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,16404657 0,19178623 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,16404657 0,19169308 ! osteoblast differentiation GO:0001649 60 25 0,000 0,16404657 0,19160003 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,16404657 0,19150706 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,16404657 0,19141419 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,16404657 0,1913214 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,16404657 0,19122871 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,16404657 0,1911361 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,16404657 0,19104359 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,16404657 0,19095116 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,16404657 0,19085883 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,16404657 0,19076658 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,16404657 0,19067442 ! telomere organization GO:0032200 43 25 0,000 0,16404657 0,19058235 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,16404657 0,19049037 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,17001926 0,1973306 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,17001926 0,19723545 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,17001926 0,1971404 ! initiation of viral infection GO:0019059 57 26 0,000 0,17001926 0,19704544 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,17001926 0,19695057 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,17001926 0,19685579 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,17001926 0,1967611 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,17001926 0,1966665 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,17001926 0,196572 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,17001926 0,19647758 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,17001926 0,19638326 GO:0051297|centrosome organization, ! response to estradiol stimulus GO:0032355 40 26 0,000 0,17001926 0,19628903 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,17001926 0,19619488 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,17001926 0,19610083 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,17001926 0,19600687 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,17001926 0,19591299 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,17001926 0,19581921 ! blastocyst development GO:0001824 49 26 0,000 0,17001926 0,19572552 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,17001926 0,19563191 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,17001926 0,1955384 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,17594946 0,20226202 ! iron ion transport GO:0006826 59 27 0,000 0,17594946 0,20216543 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,17594946 0,20206893 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,17594946 0,20197252 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,17594946 0,20187621 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,17594946 0,20177998 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,17594946 0,20168385 ! autophagy GO:0006914 41 27 0,000 0,17594946 0,20158781 ! base-excision repair GO:0006284 41 27 0,000 0,17594946 0,20149186 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,17594946 0,20139601 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,17594946 0,20130024 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,17594946 0,20120457 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,17594946 0,20110898 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,18183749 0,20774027 ! circadian rhythm GO:0007623 50 28 0,000 0,18183749 0,20764168 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,18183749 0,20754317 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,18183749 0,20744477 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,18183749 0,20734645 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,18183749 0,20724823 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,18183749 0,2071501 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,18183749 0,20705206 ! synaptogenesis GO:0007416 42 28 0,000 0,18183749 0,20695412 ! lipid oxidation GO:0034440 43 28 0,000 0,18183749 0,20685627 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,18183749 0,20675851 ! translational initiation GO:0006413 65 29 0,000 0,18768365 0,21330508 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,18768365 0,21320437 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,18768365 0,21310376 ! regulation of pH GO:0006885 43 29 0,000 0,18768365 0,21300323 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,18768365 0,21290281 ! catechol metabolic process GO:0009712 54 29 0,000 0,18768365 0,21280248 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,18768365 0,21270224 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,18768365 0,2126021 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,18768365 0,21250205 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,18768365 0,2124021 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,18768365 0,21230224 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,18768365 0,21220247 ! detection of light stimulus GO:0009583 38 29 0,000 0,18768365 0,2121028 ! phenol metabolic process GO:0018958 55 30 0,000 0,19348822 0,21855994 ! zinc ion transport GO:0006829 45 30 0,000 0,19348822 0,21845737 ! membrane docking GO:0022406 61 30 0,000 0,19348822 0,21835491 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,19348822 0,21825254 ! regulation of innate immune response GO:0045088 51 30 0,000 0,19348822 0,21815026 ! acute-phase response GO:0006953 49 30 0,000 0,19348822 0,21804809 ! myofibril assembly GO:0030239 47 30 0,000 0,19348822 0,217946 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,19348822 0,21784402 ! phospholipid transport GO:0015914 51 30 0,000 0,19348822 0,21774212 ! ensheathment of neurons GO:0007272 57 30 0,000 0,19348822 0,21764033 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,19348822 0,21753863 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,19348822 0,21743702 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,19348822 0,21733551 ! eye morphogenesis GO:0048592 60 30 0,000 0,19348822 0,21723409 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,19925151 0,22360034 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,19925151 0,2234961 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,19925151 0,22339195 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,19925151 0,22328791 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,19925151 0,22318395 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,19925151 0,2230801 ! peptide transport GO:0015833 55 31 0,000 0,19925151 0,22297634 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,19925151 0,22287268 ! mesoderm formation GO:0001707 69 31 0,000 0,19925151 0,22276911 ! natural killer cell activation GO:0030101 45 31 0,000 0,19925151 0,22266564 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,19925151 0,22256227 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,19925151 0,22245899 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,19925151 0,22235581 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,2049738 0,22863559 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,2049738 0,22852964 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,2049738 0,22842379 ! cholesterol transport GO:0030301 56 32 0,000 0,2049738 0,22831804 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,2049738 0,22821239 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,2049738 0,22810683 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,2049738 0,22800137 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,2049738 0,22789601 ! muscle cell development GO:0055001 49 32 0,000 0,2049738 0,22779075 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,2049738 0,22768558 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,2049738 0,22758051 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,2049738 0,22747554 ! peripheral nervous system development GO:0007422 64 32 0,000 0,2049738 0,22737066 ! BMP signaling pathway GO:0030509 64 32 0,000 0,2049738 0,22726589 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,2049738 0,2271612 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,2049738 0,22705662 ! gene silencing GO:0016458 65 32 0,000 0,2049738 0,22695213 ! protein targeting to membrane GO:0006612 68 33 0,000 0,21065539 0,23313564 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,21065539 0,23302845 ! ceramide metabolic process GO:0006672 64 33 0,000 0,21065539 0,23292136 ! formation of primary germ layer GO:0001704 72 33 0,000 0,21065539 0,23281437 ! sterol transport GO:0015918 57 33 0,000 0,21065539 0,23270747 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,21065539 0,23260068 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,21065539 0,23249398 ! adult locomotory behavior GO:0008344 59 33 0,000 0,21065539 0,23238738 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,21065539 0,23228088 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,21065539 0,23217447 ! glial cell differentiation GO:0010001 63 34 0,000 0,21629657 0,23828276 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,21629657 0,2381737 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,21629657 0,23806475 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,21629657 0,23795589 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,21629657 0,23784714 ! mismatch repair GO:0006298 46 34 0,000 0,21629657 0,23773848 ! spermatid development GO:0007286 63 34 0,000 0,21629657 0,23762993 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,21629657 0,23752147 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,21629657 0,23741311 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,22189761 0,24344991 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,22189761 0,24333895 ! odontogenesis GO:0042476 66 35 0,000 0,22189761 0,24322809 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,22189761 0,24311733 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,22189761 0,24300667 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,22189761 0,24289611 ! vesicle localization GO:0051648 64 35 0,000 0,22189761 0,24278566 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,22745881 0,24875723 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,22745881 0,24864421 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,22745881 0,24853129 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,22745881 0,24841848 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,22745881 0,24830576 ! aerobic respiration GO:0009060 55 36 0,000 0,22745881 0,24819315 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,22745881 0,24808064 ! RNA export from nucleus GO:0006405 56 37 0,000 0,23298045 0,25398775 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,23298045 0,25387272 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,23298045 0,25375779 ! actomyosin structure organization GO:0031032 62 37 0,000 0,23298045 0,25364297 ! organic anion transport GO:0015711 68 37 0,000 0,23298045 0,25352825 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,23298045 0,25341364 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,23298045 0,25329912 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,23298045 0,25318472 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,23298045 0,25307041 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,23298045 0,25295621 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,2384628 0,25879184 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,2384628 0,25867516 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,2384628 0,25855859 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,2384628 0,25844212 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,2384628 0,25832576 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,2384628 0,2582095 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,2384628 0,25809334 ! mRNA catabolic process GO:0006402 71 39 0,000 0,24390615 0,2638661 ! mammary gland development GO:0030879 86 39 0,000 0,24390615 0,26374751 ! learning GO:0007612 77 39 0,000 0,24390615 0,26362902 ! organic ether metabolic process GO:0018904 55 39 0,000 0,24390615 0,26351064 ! ion transmembrane transport GO:0034220 66 39 0,000 0,24390615 0,26339237 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,24390615 0,2632742 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,24390615 0,26315614 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,24390615 0,26303819 ! RNA modification GO:0009451 57 39 0,000 0,24390615 0,26292034 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,24390615 0,2628026 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,24931077 0,26850569 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,24931077 0,26838556 ! feeding behavior GO:0007631 59 40 0,000 0,24931077 0,26826553 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,24931077 0,26814561 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,25467694 0,27379478 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,25467694 0,27367249 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,25467694 0,27355032 ! gliogenesis GO:0042063 88 41 0,000 0,25467694 0,27342825 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,25467694 0,2733063 ! polyol metabolic process GO:0019751 66 41 0,000 0,25467694 0,27318445 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,25467694 0,27306271 ! regulation of tube size GO:0035150 71 42 0,000 0,26000492 0,27865116 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,26000492 0,27852709 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,26000492 0,27840314 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,26000492 0,27827929 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,26000492 0,27815556 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,265295 0,28368878 ! phagocytosis GO:0006909 90 43 0,000 0,265295 0,28356275 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,27054743 0,28904845 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,27054743 0,28892015 ! double-strand break repair GO:0006302 81 44 0,000 0,27054743 0,28879197 ! biopolymer methylation GO:0043414 84 44 0,000 0,27054743 0,28866391 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,27054743 0,28853595 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,27576248 0,29396745 ! glycolysis GO:0006096 65 45 0,000 0,27576248 0,29383726 ! leukocyte migration GO:0050900 68 45 0,000 0,27576248 0,29370718 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,27576248 0,29357722 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,27576248 0,29344738 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,27576248 0,29331765 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,27576248 0,29318804 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,28094042 0,29856124 ! endosome transport GO:0016197 108 47 0,000 0,28608151 0,30389056 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,28608151 0,30375645 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,28608151 0,30362246 ! JNK cascade GO:0007254 91 47 0,000 0,28608151 0,30348859 ! methylation GO:0032259 90 47 0,000 0,28608151 0,30335484 ! protein homooligomerization GO:0051260 76 47 0,000 0,28608151 0,3032212 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,29118602 0,30849562 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,29118602 0,30835984 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2962542 0,31358891 ! regulation of action potential GO:0001508 95 49 0,000 0,2962542 0,31345101 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,2962542 0,31331323 ! regulation of ion transport GO:0043269 77 49 0,000 0,2962542 0,31317557 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2962542 0,31303803 ! endocrine system development GO:0035270 104 49 0,000 0,2962542 0,31290061 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2962542 0,31276332 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,2962542 0,31262614 GO:0019724|B cell mediated immunity, ! regulation of cell projection organization GO:0031344 121 50 0,000 0,3012863 0,31779695 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,3012863 0,31765769 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,30628259 0,32278402 ! excretion GO:0007588 83 51 0,000 0,30628259 0,3226427 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,30628259 0,32250149 ! chromatin remodeling GO:0006338 109 51 0,000 0,30628259 0,32236042 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,30628259 0,32221946 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,31124332 0,3272952 ! membrane fusion GO:0006944 110 52 0,000 0,31124332 0,32715222 ! amino acid activation GO:0043038 92 52 0,000 0,31124332 0,32700936 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! RNA catabolic process GO:0006401 93 53 0,000 0,31616874 0,33203928 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,31616874 0,33189441 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,31616874 0,33174967 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,31616874 0,33160505 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,31616874 0,33146056 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,3210591 0,33644085 ! cell recognition GO:0008037 85 54 0,000 0,3210591 0,33629438 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,3210591 0,33614803 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,3210591 0,33600182 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,3210591 0,33585573 ! chloride transport GO:0006821 90 55 0,000 0,32591464 0,34078689 ! glucose catabolic process GO:0006007 82 55 0,000 0,32591464 0,34063885 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,32591464 0,34049094 ! gastrulation GO:0007369 112 55 0,000 0,32591464 0,34034315 ! RNA elongation GO:0006354 79 55 0,000 0,32591464 0,3401955 ! nuclear export GO:0051168 97 55 0,000 0,32591464 0,34004797 ! regulation of actin filament length GO:0030832 105 56 0,000 0,33073562 0,34492844 ! sensory perception of smell GO:0007608 80 56 0,000 0,33073562 0,34477899 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,33073562 0,34462967 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,33073562 0,34448048 ! proton transport GO:0015992 94 56 0,000 0,33073562 0,34433142 ! hydrogen transport GO:0006818 97 58 0,000 0,34027487 0,35410958 ! regulation of endocytosis GO:0030100 91 58 0,000 0,34027487 0,35395648 ! adult behavior GO:0030534 99 58 0,000 0,34027487 0,35380352 ! positive regulation of secretion GO:0051047 95 59 0,000 0,34499362 0,35855492 ! regulation of cellular component size GO:0032535 109 59 0,000 0,34499362 0,35840011 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,34499362 0,35824543 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,34967877 0,3629539 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,34967877 0,36279738 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,34967877 0,36264101 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,35433057 0,36730692 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,35433057 0,36714873 ! mesoderm development GO:0007498 119 61 0,000 0,35433057 0,36699068 ! tRNA processing GO:0008033 89 61 0,000 0,35433057 0,36683277 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,35433057 0,36667499 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,35894925 0,37129488 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,36353504 0,37587679 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,36353504 0,37571534 ! cell redox homeostasis GO:0045454 102 64 0,000 0,36808817 0,38025768 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,36808817 0,38009448 ! single fertilization GO:0007338 75 64 0,000 0,36808817 0,37993142 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,37260889 0,38443267 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,37260889 0,38426789 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,37709741 0,38873024 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,37709741 0,38856376 ! extracellular matrix organization GO:0030198 133 66 0,000 0,37709741 0,38839742 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,38155397 0,39281936 ! hexose catabolic process GO:0019320 104 67 0,000 0,38155397 0,39265135 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,38155397 0,39248348 ! activation of immune response GO:0002253 105 67 0,000 0,38155397 0,39231575 ! amino acid transport GO:0006865 125 68 0,000 0,38597879 0,39669585 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,38597879 0,39652646 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,3903721 0,40086866 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,3903721 0,40069764 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,3903721 0,40052677 ! antigen processing and presentation GO:0019882 104 69 0,000 0,3903721 0,40035604 ! amine catabolic process GO:0009310 117 71 0,000 0,39906508 0,40909696 ! regulation of immune effector process GO:0002697 137 71 0,000 0,39906508 0,40892273 ! acute inflammatory response GO:0002526 113 72 0,000 0,40336518 0,4131531 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,40763466 0,41734851 ! axon guidance GO:0007411 139 73 0,000 0,40763466 0,41717099 ! fertilization GO:0009566 90 73 0,000 0,40763466 0,41699362 ! transition metal ion transport GO:0000041 126 74 0,000 0,41187373 0,42115095 ! neurotransmitter transport GO:0006836 123 74 0,000 0,41187373 0,42097204 ! exocytosis GO:0006887 133 74 0,000 0,41187373 0,42079329 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,41187373 0,42061468 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,41187373 0,42043623 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,4160826 0,42455248 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,4160826 0,42437251 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,42026149 0,42845303 ! defense response to bacterium GO:0042742 89 76 0,000 0,42026149 0,42827156 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,42026149 0,42809024 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,42026149 0,42790908 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,42441062 0,43195091 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,42441062 0,43176826 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,4326204 0,43993435 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,4326204 0,43974849 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,43668147 0,44368903 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,43668147 0,44350174 ! inorganic anion transport GO:0015698 138 80 0,000 0,43668147 0,44331461 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,44071362 0,4472193 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,44471703 0,45109156 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,44471703 0,45090146 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,44471703 0,45071153 ! regulation of lyase activity GO:0051339 160 83 0,000 0,44869192 0,45454853 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,45263849 0,45835362 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,45263849 0,45816079 ! nucleosome assembly GO:0006334 122 85 0,000 0,45655694 0,46193271 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,45655694 0,46173854 ! amine biosynthetic process GO:0009309 138 86 0,000 0,46044746 0,46547756 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,46044746 0,46528206 ! chromatin assembly GO:0031497 124 86 0,000 0,46044746 0,46508673 ! alcohol catabolic process GO:0046164 130 86 0,000 0,46044746 0,46489156 ! amine transport GO:0015837 155 86 0,000 0,46044746 0,46469656 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,46431026 0,46839853 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,46431026 0,46820222 ! regulation of neurological system process GO:0031644 148 88 0,000 0,46814554 0,47187187 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,46814554 0,47167427 ! cellular defense response GO:0006968 114 89 0,000 0,47195348 0,47531188 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,47573429 0,47891912 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,47573429 0,47871882 ! sterol metabolic process GO:0016125 152 91 0,000 0,47948814 0,48229451 ! nucleosome organization GO:0034728 138 92 0,000 0,48321525 0,48584032 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,48321525 0,48563738 ! vitamin metabolic process GO:0006766 139 92 0,000 0,48321525 0,48543461 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,48691579 0,48894799 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,49058995 0,49243197 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,49423793 0,49588676 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,4978599 0,4993126 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,4978599 0,49910455 ! positive regulation of immune response GO:0050778 156 96 0,000 0,4978599 0,49889668 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,50145605 0,50229112 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,50502657 0,50565707 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,50502657 0,50544673 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,50857164 0,5087831 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,50857164 0,50857164