pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1185-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 4,000 3,367E-10 8,1E-07 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 2,577E-09 3,101E-06 ! positive regulation of vasoconstriction GO:0045907 9 5 2,000 6,759E-08 5,421E-05 ! positive regulation of microtubule polymerization GO:0031116 13 6 2,000 1,35E-07 8,12E-05 ! vasculogenesis GO:0001570 46 25 3,000 1,519E-07 7,312E-05 ! regulation of endothelial cell proliferation GO:0001936 57 26 3,000 1,793E-07 7,191E-05 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 2,359E-07 8,109E-05 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 2,000 2,359E-07 7,096E-05 ! regulation of microtubule polymerization GO:0031113 15 7 2,000 2,359E-07 6,307E-05 ! protein oligomerization GO:0051259 139 78 4,000 4,21E-07 1,013E-04 ! regulation of epithelial cell differentiation GO:0030856 14 9 2,000 5,647E-07 1,235E-04 ! gas homeostasis GO:0033483 16 9 2,000 5,647E-07 1,132E-04 ! tissue remodeling GO:0048771 76 37 3,000 7,798E-07 1,443E-04 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 8,056E-07 1,384E-04 ! gland morphogenesis GO:0022612 29 12 2,000 1,473E-06 2,362E-04 ! lipid localization GO:0010876 28 13 2,000 1,912E-06 2,875E-04 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 25 13 2,000 1,912E-06 2,706E-04 ! protein homooligomerization GO:0051260 76 47 3,000 2,076E-06 2,775E-04 ! regulation of vasodilation GO:0042312 26 15 2,000 3,034E-06 3,842E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 3,034E-06 3,65E-04 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 2,000 3,729E-06 4,272E-04 ! positive regulation of organelle organization GO:0010638 100 56 3,000 4,22E-06 4,615E-04 ! positive regulation of protein complex assembly GO:0031334 32 17 2,000 4,521E-06 4,73E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 4,521E-06 4,533E-04 ! positive regulation of cell migration GO:0030335 126 57 3,000 4,532E-06 4,362E-04 ! positive regulation of cell motion GO:0051272 146 64 3,000 7,217E-06 6,678E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 7,549E-06 6,727E-04 ! regulation of fatty acid metabolic process GO:0019217 38 20 2,000 7,549E-06 6,487E-04 ! inactivation of MAPK activity GO:0000188 39 21 2,000 8,795E-06 7,297E-04 ! regulation of vasoconstriction GO:0019229 39 21 2,000 8,795E-06 7,054E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,017E-05 7,893E-04 ! positive regulation of cytoskeleton organization GO:0051495 48 22 2,000 1,017E-05 7,646E-04 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,017E-05 7,415E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 1,017E-05 7,197E-04 ! membrane depolarization GO:0051899 39 24 2,000 1,333E-05 9,163E-04 ! regulation of smooth muscle contraction GO:0006940 43 25 2,000 1,513E-05 1,011E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 1,513E-05 9,836E-04 ! regulation of blood coagulation GO:0030193 40 25 2,000 1,513E-05 9,577E-04 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,67E-05 1,03E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,708E-05 1,027E-03 ! regulation of cellular ketone metabolic process GO:0010565 44 26 2,000 1,708E-05 1,002E-03 ! response to hypoxia GO:0001666 171 81 3,000 1,844E-05 1,057E-03 ! response to oxygen levels GO:0070482 176 83 3,000 2,031E-05 1,137E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 2,39E-05 1,307E-03 ! regulation of coagulation GO:0050818 46 29 2,000 2,39E-05 1,278E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 2,000 2,652E-05 1,387E-03 ! cholesterol homeostasis GO:0042632 53 31 2,000 2,932E-05 1,501E-03 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 2,000 2,932E-05 1,47E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 3,181E-05 1,562E-03 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 3,181E-05 1,531E-03 ! cholesterol transport GO:0030301 56 32 2,000 3,231E-05 1,524E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 3,231E-05 1,495E-03 ! sterol transport GO:0015918 57 33 2,000 3,549E-05 1,611E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,631E-05 1,618E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,631E-05 1,589E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,631E-05 1,56E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 3,631E-05 1,533E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,631E-05 1,506E-03 ! neutral lipid metabolic process GO:0006638 50 35 2,000 4,246E-05 1,731E-03 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 2,000 4,246E-05 1,703E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 4,626E-05 1,824E-03 ! glycerol ether metabolic process GO:0006662 53 37 2,000 5,027E-05 1,951E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 5,027E-05 1,92E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 5,44E-05 2,045E-03 ! male sex determination GO:0030238 15 6 1,000 5,44E-05 2,014E-03 ! lipid homeostasis GO:0055088 67 38 2,000 5,45E-05 1,987E-03 ! mammary gland development GO:0030879 86 39 2,000 5,896E-05 2,117E-03 ! organic ether metabolic process GO:0018904 55 39 2,000 5,896E-05 2,086E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 6,366E-05 2,22E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 80 42 2,000 7,377E-05 2,535E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,607E-05 2,578E-03 ! mRNA stabilization GO:0048255 18 7 1,000 7,607E-05 2,542E-03 GO:0043489|RNA stabilization, ! vesicle fusion GO:0006906 17 7 1,000 7,607E-05 2,507E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,607E-05 2,473E-03 ! lymph node development GO:0048535 10 7 1,000 7,607E-05 2,44E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 7,607E-05 2,408E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 7,919E-05 2,474E-03 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 9,081E-05 2,801E-03 ! cell growth GO:0016049 84 45 2,000 9,081E-05 2,766E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 9,701E-05 2,918E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 9,701E-05 2,881E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 9,701E-05 2,846E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,013E-04 2,937E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,013E-04 2,902E-03 ! ER overload response GO:0006983 12 8 1,000 1,013E-04 2,867E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,013E-04 2,834E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,013E-04 2,802E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,013E-04 2,77E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,013E-04 2,739E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 1,013E-04 2,708E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,013E-04 2,678E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,102E-04 2,883E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,301E-04 3,365E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,301E-04 3,33E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,301E-04 3,295E-03 GO:0010469|regulation of receptor activity, ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,301E-04 3,26E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 1,301E-04 3,227E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,301E-04 3,194E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,301E-04 3,161E-03 ! induction of an organ GO:0001759 14 9 1,000 1,301E-04 3,13E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 1,301E-04 3,099E-03 GO:0002820|negative regulation of adaptive immune response, ! vesicle organization GO:0016050 107 51 2,000 1,322E-04 3,118E-03 ! regulation of muscle contraction GO:0006937 81 52 2,000 1,401E-04 3,272E-03 ! regulation of protein polymerization GO:0032271 103 53 2,000 1,483E-04 3,43E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,624E-04 3,721E-03 ! lung alveolus development GO:0048286 26 10 1,000 1,624E-04 3,686E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 1,624E-04 3,652E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,624E-04 3,618E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,624E-04 3,585E-03 GO:0043470|regulation of carbohydrate catabolic process, ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 1,624E-04 3,552E-03 ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,624E-04 3,52E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,624E-04 3,489E-03 ! localization within membrane GO:0051668 20 10 1,000 1,624E-04 3,458E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,842E-04 3,888E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,982E-04 4,148E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 1,982E-04 4,112E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,982E-04 4,077E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,982E-04 4,042E-03 ! developmental induction GO:0031128 19 11 1,000 1,982E-04 4,008E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 1,982E-04 3,975E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 2,145E-04 4,266E-03 ! regulation of protein complex assembly GO:0043254 117 61 2,000 2,253E-04 4,444E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,253E-04 4,408E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,376E-04 4,61E-03 ! virus-host interaction GO:0019048 29 12 1,000 2,376E-04 4,573E-03 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,376E-04 4,537E-03 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,376E-04 4,501E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,376E-04 4,466E-03 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 2,479E-04 4,625E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,479E-04 4,589E-03 ! organelle fusion GO:0048284 32 13 1,000 2,805E-04 5,151E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,805E-04 5,112E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,805E-04 5,074E-03 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,805E-04 5,036E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 2,975E-04 5,302E-03 ! activation of MAPK activity GO:0000187 115 67 2,000 2,975E-04 5,263E-03 ! lung development GO:0030324 144 67 2,000 2,975E-04 5,224E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 3,108E-04 5,418E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 3,108E-04 5,38E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,268E-04 5,616E-03 GO:0060675|ureteric bud morphogenesis, ! regulation of RNA stability GO:0043487 32 14 1,000 3,268E-04 5,576E-03 ! respiratory tube development GO:0030323 150 70 2,000 3,385E-04 5,736E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 3,53E-04 5,939E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 3,678E-04 6,146E-03 ! respiratory system development GO:0060541 153 72 2,000 3,678E-04 6,104E-03 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,766E-04 6,206E-03 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 3,766E-04 6,164E-03 ! cell-matrix adhesion GO:0007160 163 75 2,000 4,148E-04 6,743E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,299E-04 6,941E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 4,299E-04 6,895E-03 ! negative regulation of immune response GO:0050777 35 16 1,000 4,299E-04 6,849E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,299E-04 6,804E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,299E-04 6,76E-03 ! signal complex assembly GO:0007172 41 17 1,000 4,866E-04 7,602E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,866E-04 7,553E-03 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,866E-04 7,505E-03 ! cell-substrate adhesion GO:0031589 171 81 2,000 5,198E-04 7,966E-03 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 5,388E-04 8,205E-03 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,467E-04 8,273E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 5,467E-04 8,221E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,467E-04 8,17E-03 ! lipid phosphorylation GO:0046834 35 19 1,000 6,103E-04 9,064E-03 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 6,103E-04 9,008E-03 ! regulation of protein transport GO:0051223 154 87 2,000 6,405E-04 9,397E-03 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 2,000 6,622E-04 9,656E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,773E-04 9,816E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine modification GO:0018209 43 20 1,000 6,773E-04 9,758E-03 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 6,773E-04 9,699E-03 ! regulation of cell killing GO:0031341 42 21 1,000 7,476E-04 0,01064384 ! positive regulation of locomotion GO:0040017 39 21 1,000 7,476E-04 0,01058123 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of membrane potential GO:0042391 164 93 2,000 7,778E-04 0,01094309 ! regulation of chemotaxis GO:0050920 40 22 1,000 8,214E-04 0,01148978 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 8,214E-04 0,01142337 ! ureteric bud development GO:0001657 43 22 1,000 8,214E-04 0,01135772 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 8,789E-04 0,0120833 ! regulation of protein localization GO:0032880 176 97 2,000 8,789E-04 0,01201465 ! positive regulation of DNA replication GO:0045740 43 23 1,000 8,985E-04 0,01221345 ! regulation of DNA recombination GO:0000018 48 23 1,000 8,985E-04 0,01214483 ! sex determination GO:0007530 47 23 1,000 8,985E-04 0,01207698 ! skeletal muscle tissue development GO:0007519 186 99 2,000 9,324E-04 0,01246334 GO:0060538|skeletal muscle organ development, ! regulation of cellular catabolic process GO:0031329 52 24 1,000 9,79E-04 0,01301321 ! vesicle docking GO:0048278 47 24 1,000 9,79E-04 0,0129417 ! regulation of behavior GO:0050795 43 24 1,000 9,79E-04 0,01287098 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 9,79E-04 0,01280103 ! protein tetramerization GO:0051262 52 24 1,000 9,79E-04 0,01273184 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,063E-03 0,01374754 ! interaction with host GO:0051701 62 25 1,000 1,063E-03 0,01367402 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,15E-03 0,01471652 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,15E-03 0,01463865 ! cellular response to oxidative stress GO:0034599 39 26 1,000 1,15E-03 0,01456161 ! positive regulation of nuclear division GO:0051785 40 26 1,000 1,15E-03 0,01448537 GO:0045840|positive regulation of mitosis, ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 1,24E-03 0,01554348 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,24E-03 0,01546295 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,334E-03 0,0165461 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 1,334E-03 0,01646125 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,334E-03 0,01637726 ! membrane docking GO:0022406 61 30 1,000 1,532E-03 0,01870488 ! metanephros development GO:0001656 74 32 1,000 1,742E-03 0,02116776 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 1,742E-03 0,02106139 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 1,742E-03 0,02095608 ! positive regulation of catabolic process GO:0009896 64 32 1,000 1,742E-03 0,02085182 ! cell fate specification GO:0001708 52 33 1,000 1,852E-03 0,02205994 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 1,965E-03 0,02329443 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 2,082E-03 0,02455475 ! calcium-mediated signaling GO:0019722 62 35 1,000 2,082E-03 0,02443497 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 2,325E-03 0,02715083 ! glycogen metabolic process GO:0005977 61 37 1,000 2,325E-03 0,02701966 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 2,451E-03 0,02834861 ! carbohydrate homeostasis GO:0033500 53 38 1,000 2,451E-03 0,02821297 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 62 38 1,000 2,451E-03 0,02807863 GO:0006073|cellular glucan metabolic process, ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 2,58E-03 0,02941978 ! T cell differentiation GO:0030217 81 41 1,000 2,848E-03 0,03232284 ! regulation of T cell differentiation GO:0045580 70 41 1,000 2,848E-03 0,03217109 ! response to reactive oxygen species GO:0000302 67 42 1,000 2,987E-03 0,03358033 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 2,987E-03 0,03342414 ! energy reserve metabolic process GO:0006112 74 43 1,000 3,129E-03 0,03484927 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 3,129E-03 0,03468867 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 3,274E-03 0,03612921 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 3,422E-03 0,03759059 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 3,573E-03 0,0390724 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 3,573E-03 0,0388956 ! vascular process in circulatory system GO:0003018 80 47 1,000 3,727E-03 0,04039145 ! regulation of adaptive immune response GO:0002819 84 47 1,000 3,727E-03 0,04021033 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 3,884E-03 0,04171981 ! negative regulation of immune system process GO:0002683 95 50 1,000 4,208E-03 0,04499497 ! regulation of cell shape GO:0008360 125 51 1,000 4,374E-03 0,04656684 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 4,374E-03 0,0463617 ! membrane fusion GO:0006944 110 52 1,000 4,543E-03 0,04794557 ! positive regulation of growth GO:0045927 90 52 1,000 4,543E-03 0,0477362 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 4,543E-03 0,04752865 ! response to UV GO:0009411 104 53 1,000 4,716E-03 0,04911813 ! activation of phospholipase C activity GO:0007202 103 54 1,000 4,891E-03 0,0507249 GO:0010863|positive regulation of phospholipase C activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 5,07E-03 0,05234859 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 5,07E-03 0,05212488 ! heart morphogenesis GO:0003007 97 55 1,000 5,07E-03 0,05190307 ! regulation of DNA replication GO:0006275 101 56 1,000 5,251E-03 0,05353136 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 5,435E-03 0,05517587 ! regulation of bone remodeling GO:0046850 137 57 1,000 5,435E-03 0,05494404 ! lipid modification GO:0030258 97 57 1,000 5,435E-03 0,05471415 ! regulation of phospholipase activity GO:0010517 106 57 1,000 5,435E-03 0,05448617 ! regulation of tissue remodeling GO:0034103 140 58 1,000 5,622E-03 0,05612878 ! positive regulation of lipase activity GO:0060193 108 58 1,000 5,622E-03 0,05589685 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 5,812E-03 0,05754914 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 6,005E-03 0,05921665 ! kidney development GO:0001822 122 60 1,000 6,005E-03 0,05897495 ! viral reproductive process GO:0022415 126 62 1,000 6,4E-03 0,06259616 ! regulation of homeostatic process GO:0032844 134 62 1,000 6,4E-03 0,06234273 ! regulation of mitosis GO:0007088 105 63 1,000 6,602E-03 0,06404826 GO:0051783|regulation of nuclear division, ! germ cell development GO:0007281 118 65 1,000 7,014E-03 0,06777228 ! homeostasis of number of cells GO:0048872 114 67 1,000 7,437E-03 0,07157616 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 7,437E-03 0,071291 ! positive regulation of T cell activation GO:0050870 109 67 1,000 7,437E-03 0,0710081 ! adaptive immune response GO:0002250 119 67 1,000 7,437E-03 0,07072743 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 7,653E-03 0,07249459 ! regulation of lipase activity GO:0060191 130 68 1,000 7,653E-03 0,0722103 ! urogenital system development GO:0001655 137 69 1,000 7,872E-03 0,0739843 ! regulation of immune effector process GO:0002697 137 71 1,000 8,318E-03 0,07787122 ! regulation of caspase activity GO:0043281 122 72 1,000 8,545E-03 0,07968766 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 8,545E-03 0,07937998 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 9,008E-03 0,0833554 ! lymphocyte differentiation GO:0030098 167 75 1,000 9,243E-03 0,08520624 ! regulation of catabolic process GO:0009894 161 76 1,000 9,481E-03 0,08706808 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 9,593E-03 0,08775708 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 9,593E-03 0,08742466 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,593E-03 0,08709476 ! positive regulation of helicase activity GO:0051096 11 5 0,000 9,593E-03 0,08676734 ! neuron fate determination GO:0048664 7 5 0,000 9,593E-03 0,08644236 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,593E-03 0,08611982 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 9,593E-03 0,08579967 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 9,593E-03 0,08548189 ! polyol transport GO:0015791 12 5 0,000 9,593E-03 0,08516646 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 9,593E-03 0,08485335 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,593E-03 0,08454253 ! response to superoxide GO:0000303 10 5 0,000 9,593E-03 0,08423398 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 9,593E-03 0,08392768 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 9,593E-03 0,08362359 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,593E-03 0,0833217 ! female meiosis GO:0007143 7 5 0,000 9,593E-03 0,08302198 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,593E-03 0,08272441 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,593E-03 0,08242897 ! cobalt ion transport GO:0006824 11 5 0,000 9,593E-03 0,08213563 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 9,593E-03 0,08184437 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 9,593E-03 0,08155516 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 9,593E-03 0,081268 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,593E-03 0,08098285 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,593E-03 0,08069969 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 9,593E-03 0,08041851 ! embryonic camera-type eye development GO:0031076 10 5 0,000 9,593E-03 0,08013927 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,593E-03 0,07986198 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 9,593E-03 0,07958659 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 9,593E-03 0,0793131 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,593E-03 0,07904148 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,593E-03 0,07877171 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,593E-03 0,07850378 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 9,593E-03 0,07823766 ! negative chemotaxis GO:0050919 14 5 0,000 9,593E-03 0,07797335 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,593E-03 0,07771081 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,593E-03 0,07745004 ! sensory perception of bitter taste GO:0050913 7 5 0,000 9,593E-03 0,07719101 ! behavioral response to pain GO:0048266 9 5 0,000 9,593E-03 0,0769337 ! clathrin coat assembly GO:0048268 14 5 0,000 9,593E-03 0,07667811 ! Notch receptor processing GO:0007220 8 5 0,000 9,593E-03 0,07642421 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,593E-03 0,07617198 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,593E-03 0,07592142 ! micturition GO:0060073 9 5 0,000 9,593E-03 0,0756725 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,593E-03 0,0754252 ! copulation GO:0007620 9 5 0,000 9,593E-03 0,07517952 ! glial cell fate commitment GO:0021781 13 5 0,000 9,593E-03 0,07493543 ! protein maturation by protein folding GO:0022417 13 5 0,000 9,593E-03 0,07469292 ! spermidine metabolic process GO:0008216 7 5 0,000 9,593E-03 0,07445197 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,593E-03 0,07421258 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,593E-03 0,07397472 ! apoptotic cell clearance GO:0043277 20 5 0,000 9,593E-03 0,07373837 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,593E-03 0,07350354 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,593E-03 0,07327019 ! grooming behavior GO:0007625 6 5 0,000 9,593E-03 0,07303833 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,593E-03 0,07280792 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 9,593E-03 0,07257897 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,593E-03 0,07235145 ! response to protozoan GO:0001562 10 5 0,000 9,593E-03 0,07212535 ! lymph vessel development GO:0001945 10 5 0,000 9,593E-03 0,07190066 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 9,593E-03 0,07167736 ! endochondral ossification GO:0001958 16 5 0,000 9,593E-03 0,07145545 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,593E-03 0,07123491 ! parathyroid gland development GO:0060017 13 5 0,000 9,593E-03 0,07101573 ! anagen GO:0042640 6 5 0,000 9,593E-03 0,07079789 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,593E-03 0,07058138 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,593E-03 0,07036619 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 9,593E-03 0,07015231 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 9,593E-03 0,06993973 ! dorsal spinal cord development GO:0021516 7 5 0,000 9,593E-03 0,06972843 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 9,593E-03 0,06951841 ! sphingoid catabolic process GO:0046521 6 5 0,000 9,593E-03 0,06930964 ! skeletal myofibril assembly GO:0014866 10 5 0,000 9,593E-03 0,06910213 ! smooth muscle tissue development GO:0048745 28 5 0,000 9,593E-03 0,06889585 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,593E-03 0,06869081 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,593E-03 0,06848698 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,593E-03 0,06828435 ! cardiac muscle fiber development GO:0048739 10 5 0,000 9,593E-03 0,06808292 ! transepithelial chloride transport GO:0030321 9 5 0,000 9,593E-03 0,06788268 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,593E-03 0,06768361 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 9,593E-03 0,06748571 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 9,593E-03 0,06728895 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,593E-03 0,06709335 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,593E-03 0,06689887 ! histidine catabolic process GO:0006548 6 5 0,000 9,593E-03 0,06670552 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 9,593E-03 0,06651329 ! microvillus organization GO:0032528 7 5 0,000 9,593E-03 0,06632216 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 9,593E-03 0,06613212 ! L-serine biosynthetic process GO:0006564 6 5 0,000 9,593E-03 0,06594317 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,593E-03 0,0657553 ! tryptophan metabolic process GO:0006568 9 5 0,000 9,593E-03 0,0655685 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 9,593E-03 0,06538275 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,593E-03 0,06519805 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 9,593E-03 0,0650144 ! polyol catabolic process GO:0046174 7 5 0,000 9,593E-03 0,06483177 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 9,593E-03 0,06465017 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,593E-03 0,06446958 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,593E-03 0,06429 ! muscle cell migration GO:0014812 8 5 0,000 9,593E-03 0,06411142 ! mitochondrial fission GO:0000266 8 5 0,000 9,593E-03 0,06393383 ! sister chromatid cohesion GO:0007062 12 5 0,000 9,593E-03 0,06375721 ! mRNA transcription GO:0009299 9 5 0,000 9,593E-03 0,06358157 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 9,593E-03 0,0634069 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 9,593E-03 0,06323318 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 9,593E-03 0,06306041 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,593E-03 0,06288859 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,593E-03 0,06271769 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,593E-03 0,06254773 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,593E-03 0,06237868 ! response to food GO:0032094 6 5 0,000 9,593E-03 0,06221054 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,593E-03 0,06204331 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,593E-03 0,06187697 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 9,593E-03 0,06171153 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,593E-03 0,06154696 ! paraxial mesoderm development GO:0048339 14 5 0,000 9,593E-03 0,06138327 ! forebrain neuron development GO:0021884 13 5 0,000 9,593E-03 0,06122045 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,593E-03 0,0610585 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 9,593E-03 0,06089739 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,593E-03 0,06073713 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,593E-03 0,06057772 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,593E-03 0,06041914 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 9,593E-03 0,06026139 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,593E-03 0,06010446 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 9,593E-03 0,05994834 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 9,593E-03 0,05979303 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 9,593E-03 0,05963853 ! basic amino acid transport GO:0015802 11 5 0,000 9,593E-03 0,05948482 ! cellular glucose homeostasis GO:0001678 5 5 0,000 9,593E-03 0,05933191 ! early endosome to late endosome transport GO:0045022 12 5 0,000 9,593E-03 0,05917977 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,593E-03 0,05902842 ! depyrimidination GO:0045008 10 5 0,000 9,593E-03 0,05887783 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,593E-03 0,05872802 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,593E-03 0,05857896 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,593E-03 0,05843066 ! zinc ion homeostasis GO:0055069 8 5 0,000 9,593E-03 0,05828311 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 9,593E-03 0,0581363 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 9,593E-03 0,05799023 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,593E-03 0,05784489 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,593E-03 0,05770028 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,593E-03 0,05755639 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 9,593E-03 0,05741321 ! peptidyl-arginine modification GO:0018195 9 5 0,000 9,593E-03 0,05727075 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,593E-03 0,05712899 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,593E-03 0,05698793 ! response to arsenic GO:0046685 10 5 0,000 9,593E-03 0,05684756 ! mast cell degranulation GO:0043303 7 5 0,000 9,593E-03 0,05670789 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 9,593E-03 0,0565689 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 9,593E-03 0,05643059 ! response to cadmium ion GO:0046686 7 5 0,000 9,593E-03 0,05629295 ! bile acid biosynthetic process GO:0006699 6 5 0,000 9,593E-03 0,05615599 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 9,593E-03 0,05601969 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,593E-03 0,05588405 ! decidualization GO:0046697 11 5 0,000 9,593E-03 0,05574906 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 9,593E-03 0,05561473 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 9,593E-03 0,05548104 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,593E-03 0,05534799 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,593E-03 0,05521558 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 9,593E-03 0,0550838 ! base conversion or substitution editing GO:0016553 5 5 0,000 9,593E-03 0,05495265 ! neural tube patterning GO:0021532 7 5 0,000 9,593E-03 0,05482212 ! embryonic cleavage GO:0040016 6 5 0,000 9,593E-03 0,05469221 ! peroxisome fission GO:0016559 5 5 0,000 9,593E-03 0,05456291 ! histone demethylation GO:0016577 10 5 0,000 9,593E-03 0,05443422 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 9,593E-03 0,05430614 ! mitotic recombination GO:0006312 9 5 0,000 9,593E-03 0,05417866 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,593E-03 0,05405178 ! metaphase plate congression GO:0051310 7 5 0,000 9,593E-03 0,05392549 ! regulation of sterol transport GO:0032371 7 5 0,000 9,593E-03 0,05379979 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,593E-03 0,05367468 ! enteric nervous system development GO:0048484 8 5 0,000 9,593E-03 0,05355014 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 9,593E-03 0,05342618 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 9,593E-03 0,0533028 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 9,593E-03 0,05317998 ! muscle cell proliferation GO:0033002 11 5 0,000 9,593E-03 0,05305773 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,593E-03 0,05293603 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 9,593E-03 0,0528149 ! plasminogen activation GO:0031639 5 5 0,000 9,593E-03 0,05269432 ! B cell homeostasis GO:0001782 13 5 0,000 9,593E-03 0,05257429 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 9,593E-03 0,0524548 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,593E-03 0,05233585 ! metaphase GO:0051323 8 5 0,000 9,593E-03 0,05221745 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 9,593E-03 0,05209957 ! cellular response to nutrient GO:0031670 8 5 0,000 9,593E-03 0,05198223 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,593E-03 0,05186542 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,593E-03 0,05174913 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,593E-03 0,05163336 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 9,593E-03 0,05151811 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 9,593E-03 0,05140337 ! response to redox state GO:0051775 5 5 0,000 9,593E-03 0,05128914 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 9,593E-03 0,05117541 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 9,593E-03 0,05106219 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,593E-03 0,05094947 ! regulation of telomerase activity GO:0051972 6 5 0,000 9,593E-03 0,05083725 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,593E-03 0,05072552 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 9,593E-03 0,05061428 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,593E-03 0,05050353 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 9,593E-03 0,05039326 ! striatum development GO:0021756 9 5 0,000 9,593E-03 0,05028347 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 9,593E-03 0,05017415 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 9,593E-03 0,05006532 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,593E-03 0,04995695 ! glial cell migration GO:0008347 11 5 0,000 9,593E-03 0,04984905 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,593E-03 0,04974162 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 9,593E-03 0,04963465 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,593E-03 0,04952814 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,593E-03 0,04942208 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,593E-03 0,04931648 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,593E-03 0,04921132 ! neuroprotection GO:0043526 6 5 0,000 9,593E-03 0,04910662 ! neural plate development GO:0001840 8 5 0,000 9,593E-03 0,04900236 ! regulation of sensory perception GO:0051931 7 5 0,000 9,593E-03 0,04889854 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,593E-03 0,04879516 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,593E-03 0,04869222 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 9,593E-03 0,04858971 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 9,593E-03 0,04848763 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,593E-03 0,04838598 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,593E-03 0,04828475 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,593E-03 0,04818395 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,593E-03 0,04808356 ! spindle assembly GO:0051225 6 5 0,000 9,593E-03 0,0479836 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 9,593E-03 0,04788405 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,593E-03 0,04778491 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,593E-03 0,04768618 ! drug metabolic process GO:0017144 6 5 0,000 9,593E-03 0,04758786 ! stem cell division GO:0017145 11 5 0,000 9,593E-03 0,04748994 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,593E-03 0,04739243 ! organ regeneration GO:0031100 7 5 0,000 9,593E-03 0,04729531 ! carnitine metabolic process GO:0009437 7 5 0,000 9,593E-03 0,04719859 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 9,593E-03 0,04710227 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,593E-03 0,04700634 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 9,722E-03 0,0475435 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01021201 0,04983794 ! T cell activation GO:0042110 168 81 1,000 0,01071268 0,05217554 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01071268 0,05207013 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0115004 0,0557862 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0115004 0,05567395 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0115004 0,05556216 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0115004 0,05545081 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0115004 0,05533991 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0115004 0,05522945 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0115004 0,05511943 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0115004 0,05500985 ! sleep GO:0030431 13 6 0,000 0,0115004 0,0549007 ! response to oxygen radical GO:0000305 11 6 0,000 0,0115004 0,05479199 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0115004 0,0546837 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0115004 0,05457585 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0115004 0,05446841 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0115004 0,0543614 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0115004 0,05425481 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0115004 0,05414864 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0115004 0,05404288 ! forebrain regionalization GO:0021871 8 6 0,000 0,0115004 0,05393753 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0115004 0,0538326 ! male meiosis GO:0007140 7 6 0,000 0,0115004 0,05372807 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0115004 0,05362394 ! response to zinc ion GO:0010043 9 6 0,000 0,0115004 0,05352022 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0115004 0,0534169 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0115004 0,05331398 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0115004 0,05321145 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0115004 0,05310932 ! malate metabolic process GO:0006108 11 6 0,000 0,0115004 0,05300758 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0115004 0,05290622 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0115004 0,05280526 ! protein refolding GO:0042026 15 6 0,000 0,0115004 0,05270467 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0115004 0,05260448 ! opsonization GO:0008228 8 6 0,000 0,0115004 0,05250466 ! mating behavior GO:0007617 7 6 0,000 0,0115004 0,05240522 ! neuron remodeling GO:0016322 15 6 0,000 0,0115004 0,05230615 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0115004 0,05220746 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0115004 0,05210914 ! equilibrioception GO:0050957 14 6 0,000 0,0115004 0,05201119 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0115004 0,05191361 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0115004 0,05181639 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0115004 0,05171954 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0115004 0,05162305 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0115004 0,05152692 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0115004 0,05143114 ! toxin metabolic process GO:0009404 11 6 0,000 0,0115004 0,05133572 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0115004 0,05124066 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0115004 0,05114594 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0115004 0,05105158 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0115004 0,05095756 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0115004 0,05086389 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0115004 0,05077056 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0115004 0,05067757 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0115004 0,05058493 ! thymic T cell selection GO:0045061 12 6 0,000 0,0115004 0,05049262 ! protein lipoylation GO:0009249 10 6 0,000 0,0115004 0,05040065 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0115004 0,05030901 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0115004 0,0502177 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0115004 0,05012673 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0115004 0,05003608 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0115004 0,04994577 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0115004 0,04985577 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0115004 0,0497661 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0115004 0,04967676 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0115004 0,04958773 ! hyperosmotic response GO:0006972 9 6 0,000 0,0115004 0,04949902 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0115004 0,04941063 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0115004 0,04932256 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0115004 0,04923479 ! urea metabolic process GO:0019627 7 6 0,000 0,0115004 0,04914734 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0115004 0,0490602 ! neutrophil activation GO:0042119 8 6 0,000 0,0115004 0,04897337 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0115004 0,04888684 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0115004 0,04880062 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0115004 0,04871471 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0115004 0,04862909 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0115004 0,04854378 ! neuron apoptosis GO:0051402 9 6 0,000 0,0115004 0,04845876 ! nucleoside salvage GO:0043174 9 6 0,000 0,0115004 0,04837405 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0115004 0,04828962 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0115004 0,0482055 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0115004 0,04812166 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0115004 0,04803811 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0115004 0,04795486 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0115004 0,04787189 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0115004 0,04778921 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0115004 0,04770682 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0115004 0,04762471 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0115004 0,04754288 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0115004 0,04746133 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0115004 0,04738006 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0115004 0,04729907 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0115004 0,04721835 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0115004 0,04713791 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0115004 0,04705775 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0115004 0,04697785 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0115004 0,04689823 ! neural nucleus development GO:0048857 14 6 0,000 0,0115004 0,04681887 ! response to UV-C GO:0010225 11 6 0,000 0,0115004 0,04673979 ! astrocyte development GO:0014002 15 6 0,000 0,0115004 0,04666097 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0115004 0,04658241 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0115004 0,04650412 ! interaction with symbiont GO:0051702 13 6 0,000 0,0115004 0,0464261 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0115004 0,04634833 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0115004 0,04627083 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0115004 0,04619358 ! response to copper ion GO:0046688 10 6 0,000 0,0115004 0,04611659 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0115004 0,04603986 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0115004 0,04596338 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0115004 0,04588715 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0115004 0,04581118 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0115004 0,04573546 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0115004 0,04565999 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0115004 0,04558477 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0115004 0,04550979 ! hair follicle maturation GO:0048820 7 6 0,000 0,0115004 0,04543506 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0115004 0,04536058 ! Schwann cell development GO:0014044 15 6 0,000 0,0115004 0,04528634 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0115004 0,04521234 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0115004 0,04513859 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0115004 0,04506507 ! subpallium development GO:0021544 10 6 0,000 0,0115004 0,0449918 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0115004 0,04491876 ! histone ubiquitination GO:0016574 8 6 0,000 0,0115004 0,04484595 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0115004 0,04477339 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0115004 0,04470106 ! G2 phase GO:0051319 16 6 0,000 0,0115004 0,04462896 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0115004 0,04455709 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0115004 0,04448546 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0115004 0,04441405 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0115004 0,04434288 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0115004 0,04427193 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0115004 0,0442012 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0115004 0,04413071 ! receptor internalization GO:0031623 10 6 0,000 0,0115004 0,04406044 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0115004 0,04399039 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0115004 0,04392056 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0115004 0,04385096 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0115004 0,04378157 ! protein deubiquitination GO:0016579 14 6 0,000 0,0115004 0,04371241 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,0115004 0,04364346 ! protein destabilization GO:0031648 9 6 0,000 0,0115004 0,04357473 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0115004 0,04350622 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0115004 0,04343792 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0115004 0,04336983 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0115004 0,04330196 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0115004 0,0432343 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0115004 0,04316686 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0115004 0,04309962 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0115004 0,04303259 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0115004 0,04296577 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0115004 0,04289915 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0115004 0,04283275 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0115004 0,04276654 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0115004 0,04270055 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0115004 0,04263475 ! catecholamine transport GO:0051937 9 6 0,000 0,0115004 0,04256916 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0115004 0,04250377 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0115004 0,04243858 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0115004 0,04237359 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0115004 0,0423088 ! maternal placenta development GO:0001893 12 6 0,000 0,0115004 0,0422442 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0115004 0,04217981 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0115004 0,04211561 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,0115004 0,0420516 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0115004 0,04198779 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0115004 0,04192417 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0115004 0,04186075 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01174599 0,0426901 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,01201091 0,0435871 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,01282134 0,04645803 ! ossification GO:0001503 188 90 1,000 0,01309666 0,04738431 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,01309666 0,04731317 ! bone development GO:0060348 189 91 1,000 0,01337456 0,04824467 ! tRNA transcription GO:0009304 14 7 0,000 0,01340445 0,0482801 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01340445 0,04820794 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01340445 0,04813598 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01340445 0,04806425 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01340445 0,04799272 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01340445 0,04792141 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01340445 0,04785031 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01340445 0,04777942 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01340445 0,04770874 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01340445 0,04763827 ! prostate gland development GO:0030850 13 7 0,000 0,01340445 0,04756801 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01340445 0,04749795 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01340445 0,0474281 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01340445 0,04735846 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01340445 0,04728902 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01340445 0,04721978 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01340445 0,04715074 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01340445 0,04708191 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01340445 0,04701328 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01340445 0,04694485 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01340445 0,04687661 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01340445 0,04680858 ! glycolipid transport GO:0046836 10 7 0,000 0,01340445 0,04674074 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01340445 0,0466731 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01340445 0,04660565 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01340445 0,0465384 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01340445 0,04647134 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01340445 0,04640447 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01340445 0,0463378 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01340445 0,04627132 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01340445 0,04620503 ! pericardium development GO:0060039 14 7 0,000 0,01340445 0,04613893 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01340445 0,04607301 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01340445 0,04600729 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01340445 0,04594175 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01340445 0,0458764 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01340445 0,04581123 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01340445 0,04574625 ! lipoprotein transport GO:0042953 14 7 0,000 0,01340445 0,04568146 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01340445 0,04561684 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01340445 0,04555241 ! rhythmic behavior GO:0007622 15 7 0,000 0,01340445 0,04548816 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01340445 0,0454241 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01340445 0,04536021 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01340445 0,0452965 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01340445 0,04523297 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01340445 0,04516962 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01340445 0,04510645 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01340445 0,04504345 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01340445 0,04498063 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01340445 0,04491798 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01340445 0,04485551 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01340445 0,04479321 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01340445 0,04473108 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01340445 0,04466913 ! spinal cord patterning GO:0021511 13 7 0,000 0,01340445 0,04460734 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01340445 0,04454573 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01340445 0,04448429 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01340445 0,04442301 ! adrenal gland development GO:0030325 17 7 0,000 0,01340445 0,04436191 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01340445 0,04430097 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01340445 0,0442402 ! ovulation GO:0030728 9 7 0,000 0,01340445 0,0441796 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01340445 0,04411916 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01340445 0,04405889 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01340445 0,04399878 ! microtubule nucleation GO:0007020 20 7 0,000 0,01340445 0,04393884 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01340445 0,04387906 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01340445 0,04381944 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01340445 0,04375998 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01340445 0,04370069 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01340445 0,04364155 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01340445 0,04358258 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01340445 0,04352376 ! galactose metabolic process GO:0006012 13 7 0,000 0,01340445 0,04346511 ! response to dietary excess GO:0002021 8 7 0,000 0,01340445 0,04340661 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01340445 0,04334826 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01340445 0,04329008 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01340445 0,04323205 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01340445 0,04317417 ! organ growth GO:0035265 15 7 0,000 0,01340445 0,04311646 ! purine salvage GO:0043101 10 7 0,000 0,01340445 0,04305889 ! nucleoside transport GO:0015858 8 7 0,000 0,01340445 0,04300148 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01340445 0,04294422 ! parturition GO:0007567 14 7 0,000 0,01340445 0,04288711 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01340445 0,04283016 ! rRNA modification GO:0000154 14 7 0,000 0,01340445 0,04277335 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01340445 0,0427167 ! spindle checkpoint GO:0031577 15 7 0,000 0,01340445 0,0426602 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01340445 0,04260384 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01340445 0,04254764 ! macrophage differentiation GO:0030225 11 7 0,000 0,01340445 0,04249158 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01340445 0,04243567 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01340445 0,04237991 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01340445 0,04232429 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01340445 0,04226882 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01340445 0,04221349 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01340445 0,04215831 ! fibrinolysis GO:0042730 10 7 0,000 0,01340445 0,04210328 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01340445 0,04204838 ! eating behavior GO:0042755 7 7 0,000 0,01340445 0,04199363 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01340445 0,04193902 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01340445 0,04188456 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01340445 0,04183023 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01340445 0,04177605 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01340445 0,041722 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01340445 0,0416681 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01340445 0,04161433 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01340445 0,04156071 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01340445 0,04150722 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01340445 0,04145387 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01340445 0,04140065 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01340445 0,04134758 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01340445 0,04129463 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01340445 0,04124183 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01340445 0,04118916 ! regulation of meiosis GO:0040020 12 7 0,000 0,01340445 0,04113662 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01340445 0,04108421 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01340445 0,04103194 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01340445 0,04097981 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01340445 0,0409278 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01340445 0,04087593 ! transcription termination GO:0006353 13 7 0,000 0,01340445 0,04082419 ! response to tumor cell GO:0002347 13 7 0,000 0,01340445 0,04077258 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01340445 0,0407211 ! anaphase GO:0051322 17 7 0,000 0,01340445 0,04066975 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01340445 0,04061852 ! axonal fasciculation GO:0007413 18 7 0,000 0,01340445 0,04056743 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01340445 0,04051647 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01340445 0,04046563 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01340445 0,04041492 ! diuresis GO:0030146 12 7 0,000 0,01340445 0,04036434 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01340445 0,04031389 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01340445 0,04026356 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01340445 0,04021335 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01340445 0,04016327 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01340445 0,04011332 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01340445 0,04006349 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01340445 0,04001378 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01340445 0,0399642 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01340445 0,03991474 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01340445 0,0398654 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01340445 0,03981618 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01340445 0,03976709 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01340445 0,03971811 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01340445 0,03966926 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01340445 0,03962053 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01340445 0,03957191 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01340445 0,03952342 ! adult feeding behavior GO:0008343 9 7 0,000 0,01340445 0,03947504 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01340445 0,03942678 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01340445 0,03937864 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01340445 0,03933062 ! muscle adaptation GO:0043500 14 7 0,000 0,01340445 0,03928271 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01340445 0,03923493 ! retina homeostasis GO:0001895 12 7 0,000 0,01340445 0,03918725 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01340445 0,03913969 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01340445 0,03909225 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01340445 0,03904493 ! protein prenylation GO:0018342 18 7 0,000 0,01340445 0,03899771 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01340445 0,03895061 ! regulation of T cell activation GO:0050863 158 94 1,000 0,0142236 0,04128105 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01451169 0,04206643 ! leukocyte differentiation GO:0002521 202 96 1,000 0,01480231 0,04285722 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0153049 0,04425912 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0153049 0,04420599 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0153049 0,04415299 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0153049 0,04410011 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0153049 0,04404736 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0153049 0,04399473 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0153049 0,04394223 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0153049 0,04388986 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0153049 0,04383761 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0153049 0,04378548 ! meiotic prophase I GO:0007128 13 8 0,000 0,0153049 0,04373348 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0153049 0,0436816 ! oligopeptide transport GO:0006857 15 8 0,000 0,0153049 0,04362985 ! UTP metabolic process GO:0046051 8 8 0,000 0,0153049 0,04357821 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0153049 0,0435267 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0153049 0,04347531 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0153049 0,04342405 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0153049 0,0433729 ! succinate metabolic process GO:0006105 14 8 0,000 0,0153049 0,04332187 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0153049 0,04327096 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0153049 0,04322018 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0153049 0,04316951 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0153049 0,04311896 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0153049 0,04306853 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0153049 0,04301821 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0153049 0,04296802 ! reflex GO:0060004 16 8 0,000 0,0153049 0,04291794 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0153049 0,04286798 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0153049 0,04281813 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0153049 0,0427684 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0153049 0,04271878 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0153049 0,04266928 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0153049 0,0426199 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0153049 0,04257063 ! pigment granule organization GO:0048753 16 8 0,000 0,0153049 0,04252147 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0153049 0,04247242 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0153049 0,04242349 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0153049 0,04237467 ! histidine metabolic process GO:0006547 16 8 0,000 0,0153049 0,04232597 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0153049 0,04227737 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0153049 0,04222889 ! glycine catabolic process GO:0006546 13 8 0,000 0,0153049 0,04218052 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0153049 0,04213225 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0153049 0,0420841 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0153049 0,04203606 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0153049 0,04198813 ! melanin metabolic process GO:0006582 15 8 0,000 0,0153049 0,04194031 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0153049 0,04189259 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0153049 0,04184499 ! macrophage activation GO:0042116 12 8 0,000 0,0153049 0,04179749 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0153049 0,0417501 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0153049 0,04170282 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0153049 0,04165565 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0153049 0,04160858 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0153049 0,04156161 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0153049 0,04151476 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0153049 0,04146801 ! osteoblast development GO:0002076 16 8 0,000 0,0153049 0,04142136 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0153049 0,04137482 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0153049 0,04132838 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0153049 0,04128205 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0153049 0,04123582 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0153049 0,0411897 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0153049 0,04114368 ! response to UV-B GO:0010224 16 8 0,000 0,0153049 0,04109776 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0153049 0,04105194 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0153049 0,04100623 ! intermediate filament organization GO:0045109 12 8 0,000 0,0153049 0,04096061 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0153049 0,0409151 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0153049 0,04086969 ! cellular extravasation GO:0045123 12 8 0,000 0,0153049 0,04082438 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0153049 0,04077917 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0153049 0,04073406 ! response to antibiotic GO:0046677 11 8 0,000 0,0153049 0,04068905 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0153049 0,04064414 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0153049 0,04059933 ! DNA topological change GO:0006265 12 8 0,000 0,0153049 0,04055462 ! response to tropane GO:0014073 15 8 0,000 0,0153049 0,04051 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0153049 0,04046548 ! melanosome transport GO:0032402 13 8 0,000 0,0153049 0,04042107 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0153049 0,04037674 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0153049 0,04033252 ! mast cell activation GO:0045576 14 8 0,000 0,0153049 0,04028839 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0153049 0,04024436 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0153049 0,04020043 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0153049 0,04015659 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0153049 0,04011284 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0153049 0,0400692 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0153049 0,04002564 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0153049 0,03998218 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0153049 0,03993882 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0153049 0,03989555 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0153049 0,03985237 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0153049 0,03980929 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0153049 0,0397663 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0153049 0,0397234 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0153049 0,03968059 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0153049 0,03963788 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0153049 0,03959526 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0153049 0,03955273 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0153049 0,03951029 ! hormone catabolic process GO:0042447 17 8 0,000 0,0153049 0,03946794 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0153049 0,03942569 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0153049 0,03938352 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0153049 0,03934144 ! ATP catabolic process GO:0006200 11 8 0,000 0,0153049 0,03929946 ! blastocyst growth GO:0001832 19 8 0,000 0,0153049 0,03925756 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0153049 0,03921575 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0153049 0,03917403 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0153049 0,0391324 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0153049 0,03909086 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0153049 0,03904941 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0153049 0,03900804 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0153049 0,03896676 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0153049 0,03892557 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0153049 0,03888447 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0153049 0,03884345 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0153049 0,03880252 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0153049 0,03876167 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0153049 0,03872092 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0153049 0,03868024 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0153049 0,03863965 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0153049 0,03859915 ! interphase GO:0051325 213 98 1,000 0,01539106 0,0387758 ! axon extension GO:0048675 15 9 0,000 0,01720175 0,04329228 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01720175 0,04324704 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01720175 0,0432019 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01720175 0,04315685 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01720175 0,04311189 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01720175 0,04306703 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01720175 0,04302226 ! phosphate transport GO:0006817 19 9 0,000 0,01720175 0,04297759 ! reproductive behavior GO:0019098 19 9 0,000 0,01720175 0,042933 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01720175 0,04288851 ! CTP metabolic process GO:0046036 9 9 0,000 0,01720175 0,04284412 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01720175 0,04279981 ! GTP metabolic process GO:0046039 9 9 0,000 0,01720175 0,0427556 ! RNA methylation GO:0001510 15 9 0,000 0,01720175 0,04271147 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01720175 0,04266744 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01720175 0,0426235 ! artery development GO:0060840 24 9 0,000 0,01720175 0,04257965 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01720175 0,04253589 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01720175 0,04249221 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01720175 0,04244863 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01720175 0,04240514 ! chemosensory behavior GO:0007635 20 9 0,000 0,01720175 0,04236174 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01720175 0,04231842 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01720175 0,0422752 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01720175 0,04223206 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01720175 0,04218901 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01720175 0,04214605 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01720175 0,04210317 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01720175 0,04206038 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01720175 0,04201768 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01720175 0,04197507 ! protein targeting to ER GO:0045047 22 9 0,000 0,01720175 0,04193254 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01720175 0,0418901 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01720175 0,04184774 ! T cell selection GO:0045058 23 9 0,000 0,01720175 0,04180547 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01720175 0,04176329 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01720175 0,04172119 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01720175 0,04167917 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01720175 0,04163724 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01720175 0,04159539 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01720175 0,04155363 ! mannose metabolic process GO:0006013 13 9 0,000 0,01720175 0,04151195 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01720175 0,04147036 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01720175 0,04142885 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01720175 0,04138742 ! receptor clustering GO:0043113 18 9 0,000 0,01720175 0,04134607 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01720175 0,04130481 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01720175 0,04126363 ! ruffle organization GO:0031529 15 9 0,000 0,01720175 0,04122253 ! retinol metabolic process GO:0042572 18 9 0,000 0,01720175 0,04118151 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01720175 0,04114057 ! behavioral fear response GO:0001662 22 9 0,000 0,01720175 0,04109972 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01720175 0,04105895 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01720175 0,04101825 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01720175 0,04097764 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01720175 0,04093711 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01720175 0,04089666 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01720175 0,04085628 ! segment specification GO:0007379 13 9 0,000 0,01720175 0,04081599 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01720175 0,04077578 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01720175 0,04073565 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01720175 0,04069559 ! response to amine stimulus GO:0014075 13 9 0,000 0,01720175 0,04065562 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01720175 0,04061572 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01720175 0,0405759 ! erythrocyte development GO:0048821 15 9 0,000 0,01720175 0,04053616 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01720175 0,04049649 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01720175 0,04045691 ! renal water homeostasis GO:0003091 14 9 0,000 0,01720175 0,0404174 ! postreplication repair GO:0006301 22 9 0,000 0,01720175 0,04037797 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01720175 0,04033861 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01720175 0,04029933 ! icosanoid secretion GO:0032309 15 9 0,000 0,01720175 0,04026013 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01720175 0,04022101 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01720175 0,04018196 ! regulation of cell division GO:0051302 15 9 0,000 0,01720175 0,04014298 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01720175 0,04010409 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01720175 0,04006526 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01720175 0,04002652 ! sterol catabolic process GO:0016127 11 9 0,000 0,01720175 0,03998784 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01720175 0,03994924 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01720175 0,03991072 ! S phase GO:0051320 9 9 0,000 0,01720175 0,03987227 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01720175 0,03983389 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01720175 0,03979559 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01720175 0,03975736 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01720175 0,03971921 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01720175 0,03968113 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01720175 0,03964312 ! purine base metabolic process GO:0006144 21 9 0,000 0,01720175 0,03960518 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01720175 0,03956732 ! pigment granule transport GO:0051904 17 9 0,000 0,01720175 0,03952953 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01720175 0,03949181 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01720175 0,03945416 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01720175 0,03941659 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01720175 0,03937908 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01720175 0,03934165 ! mitochondrion localization GO:0051646 15 9 0,000 0,01720175 0,03930429 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01909501 0,04358881 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01909501 0,04354749 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01909501 0,04350625 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01909501 0,04346509 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01909501 0,04342401 ! synapsis GO:0007129 13 10 0,000 0,01909501 0,043383 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01909501 0,04334208 ! N-glycan processing GO:0006491 20 10 0,000 0,01909501 0,04330123 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01909501 0,04326045 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01909501 0,04321976 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01909501 0,04317914 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01909501 0,04313859 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01909501 0,04309813 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01909501 0,04305773 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01909501 0,04301742 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01909501 0,04297718 ! androgen metabolic process GO:0008209 17 10 0,000 0,01909501 0,04293701 ! phospholipid efflux GO:0033700 16 10 0,000 0,01909501 0,04289692 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01909501 0,04285691 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01909501 0,04281696 ! pathogenesis GO:0009405 13 10 0,000 0,01909501 0,0427771 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01909501 0,0427373 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01909501 0,04269759 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01909501 0,04265794 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01909501 0,04261837 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01909501 0,04257887 ! endoderm development GO:0007492 16 10 0,000 0,01909501 0,04253945 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01909501 0,04250009 ! arginine catabolic process GO:0006527 13 10 0,000 0,01909501 0,04246082 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01909501 0,04242161 ! proline metabolic process GO:0006560 13 10 0,000 0,01909501 0,04238247 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01909501 0,04234341 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01909501 0,04230442 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01909501 0,0422655 ! V(D)J recombination GO:0033151 28 10 0,000 0,01909501 0,04222666 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01909501 0,04218788 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01909501 0,04214918 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01909501 0,04211054 ! B cell proliferation GO:0042100 18 10 0,000 0,01909501 0,04207198 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01909501 0,04203349 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01909501 0,04199507 ! multicellular organism growth GO:0035264 18 10 0,000 0,01909501 0,04195671 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01909501 0,04191843 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01909501 0,04188022 ! epithelial cell development GO:0002064 20 10 0,000 0,01909501 0,04184208 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01909501 0,04180401 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01909501 0,041766 ! macroautophagy GO:0016236 17 10 0,000 0,01909501 0,04172807 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01909501 0,0416902 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01909501 0,0416524 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01909501 0,04161468 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01909501 0,04157702 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01909501 0,04153942 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01909501 0,0415019 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01909501 0,04146444 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01909501 0,04142705 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01909501 0,04138973 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01909501 0,04135248 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01909501 0,04131529 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01909501 0,04127817 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01909501 0,04124112 ! response to dsRNA GO:0043331 20 10 0,000 0,01909501 0,04120413 ! DNA ligation GO:0006266 19 10 0,000 0,01909501 0,04116721 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01909501 0,04113035 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01909501 0,04109356 ! melanosome localization GO:0032400 16 10 0,000 0,01909501 0,04105684 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01909501 0,04102018 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01909501 0,04098359 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01909501 0,04094706 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01909501 0,0409106 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01909501 0,0408742 ! mRNA cleavage GO:0006379 17 10 0,000 0,01909501 0,04083787 ! protein sumoylation GO:0016925 15 10 0,000 0,01909501 0,0408016 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01909501 0,0407654 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01909501 0,04072926 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01909501 0,04069318 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01909501 0,04065717 ! salivary gland development GO:0007431 27 10 0,000 0,01909501 0,04062122 ! prophase GO:0051324 15 10 0,000 0,01909501 0,04058534 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01909501 0,04054952 ! apical protein localization GO:0045176 15 10 0,000 0,01909501 0,04051376 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01909501 0,04047806 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01909501 0,04044243 ! midbrain development GO:0030901 13 10 0,000 0,01909501 0,04040686 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01909501 0,04037136 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01909501 0,04033591 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01909501 0,04030053 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01909501 0,04026521 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01909501 0,04022995 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01909501 0,04019475 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01909501 0,04015962 ! detection of calcium ion GO:0005513 23 10 0,000 0,01909501 0,04012454 ! oocyte development GO:0048599 17 10 0,000 0,01909501 0,04008953 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01909501 0,04005458 ! blastocyst formation GO:0001825 17 10 0,000 0,01909501 0,04001969 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01909501 0,03998486 ! activation of innate immune response GO:0002218 12 10 0,000 0,01909501 0,03995009 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01909501 0,03991538 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01909501 0,03988073 ! response to nicotine GO:0035094 20 10 0,000 0,01909501 0,03984614 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01909501 0,03981161 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02098469 0,04371356 ! respiratory burst GO:0045730 17 11 0,000 0,02098469 0,04367575 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02098469 0,043638 ! neuron fate specification GO:0048665 17 11 0,000 0,02098469 0,04360031 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02098469 0,0435627 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02098469 0,04352514 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02098469 0,04348765 ! thyroid gland development GO:0030878 26 11 0,000 0,02098469 0,04345023 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02098469 0,04341287 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02098469 0,04337557 ! response to pain GO:0048265 24 11 0,000 0,02098469 0,04333834 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02098469 0,04330117 ! T cell proliferation GO:0042098 26 11 0,000 0,02098469 0,04326406 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02098469 0,04322702 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02098469 0,04319005 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02098469 0,04315313 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02098469 0,04311628 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02098469 0,04307949 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02098469 0,04304277 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02098469 0,0430061 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02098469 0,0429695 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02098469 0,04293296 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02098469 0,04289649 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02098469 0,04286007 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02098469 0,04282372 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02098469 0,04278743 ! lipid digestion GO:0044241 18 11 0,000 0,02098469 0,0427512 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02098469 0,04271503 ! UV protection GO:0009650 19 11 0,000 0,02098469 0,04267892 ! adult heart development GO:0007512 14 11 0,000 0,02098469 0,04264287 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02098469 0,04260689 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02098469 0,04257096 ! temperature homeostasis GO:0001659 17 11 0,000 0,02098469 0,0425351 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02098469 0,0424993 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02098469 0,04246355 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02098469 0,04242787 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02098469 0,04239225 ! regulation of organ growth GO:0046620 13 11 0,000 0,02098469 0,04235668 ! pigment granule localization GO:0051875 20 11 0,000 0,02098469 0,04232118 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02098469 0,04228573 ! vasoconstriction GO:0042310 18 11 0,000 0,02098469 0,04225035 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02098469 0,04221502 ! embryonic axis specification GO:0000578 18 11 0,000 0,02098469 0,04217975 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02098469 0,04214454 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02098469 0,04210939 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02098469 0,0420743 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02098469 0,04203927 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02098469 0,0420043 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02098469 0,04196938 ! zymogen activation GO:0031638 15 11 0,000 0,02098469 0,04193452 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02098469 0,04189972 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02098469 0,04186498 ! nucleosome positioning GO:0016584 15 11 0,000 0,02098469 0,04183029 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02098469 0,04179567 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02098469 0,04176109 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02098469 0,04172658 ! acid secretion GO:0046717 18 11 0,000 0,02098469 0,04169213 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02098469 0,04165773 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02098469 0,04162338 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02098469 0,0415891 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02098469 0,04155487 ! oocyte differentiation GO:0009994 18 11 0,000 0,02098469 0,04152069 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02098469 0,04148658 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02098469 0,04145252 ! cholesterol efflux GO:0033344 19 11 0,000 0,02098469 0,04141851 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02098469 0,04138456 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02098469 0,04135067 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02098469 0,04131683 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02098469 0,04128304 ! embryonic gut development GO:0048566 15 11 0,000 0,02098469 0,04124932 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02098469 0,04121564 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02098469 0,04118203 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02098469 0,04114846 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02098469 0,04111495 ! defense response to fungus GO:0050832 13 11 0,000 0,02098469 0,0410815 ! lysogeny GO:0030069 21 11 0,000 0,02098469 0,0410481 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02098469 0,04101476 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02098469 0,04098146 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02098469 0,04094823 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02098469 0,04091504 ! nucleus localization GO:0051647 19 11 0,000 0,02098469 0,04088191 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02098469 0,04084884 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02287079 0,04448433 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02287079 0,0444484 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02287079 0,04441252 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02287079 0,04437671 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02287079 0,04434095 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02287079 0,04430525 ! cartilage condensation GO:0001502 20 12 0,000 0,02287079 0,0442696 ! mating GO:0007618 17 12 0,000 0,02287079 0,04423402 ! protein complex disassembly GO:0043241 27 12 0,000 0,02287079 0,04419849 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02287079 0,04416302 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02287079 0,0441276 ! hippocampus development GO:0021766 26 12 0,000 0,02287079 0,04409224 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02287079 0,04405694 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02287079 0,04402169 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02287079 0,0439865 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02287079 0,04395137 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02287079 0,04391629 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02287079 0,04388127 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02287079 0,04384631 ! drug transport GO:0015893 16 12 0,000 0,02287079 0,0438114 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02287079 0,04377655 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02287079 0,04374175 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02287079 0,043707 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02287079 0,04367232 ! focal adhesion formation GO:0048041 35 12 0,000 0,02287079 0,04363768 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02287079 0,0436031 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02287079 0,04356858 ! forebrain cell migration GO:0021885 21 12 0,000 0,02287079 0,04353411 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02287079 0,0434997 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02287079 0,04346534 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02287079 0,04343103 ! entry into host cell GO:0030260 32 12 0,000 0,02287079 0,04339678 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02287079 0,04336258 ! monoamine transport GO:0015844 18 12 0,000 0,02287079 0,04332844 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02287079 0,04329435 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02287079 0,04326031 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02287079 0,04322633 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02287079 0,0431924 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02287079 0,04315852 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02287079 0,0431247 ! protein homotetramerization GO:0051289 21 12 0,000 0,02287079 0,04309093 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02287079 0,04305721 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02287079 0,04302355 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02287079 0,04298994 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02287079 0,04295638 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02287079 0,04292287 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02287079 0,04288941 ! cranial nerve development GO:0021545 20 12 0,000 0,02287079 0,04285601 ! fucose catabolic process GO:0019317 22 12 0,000 0,02287079 0,04282266 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02287079 0,04278936 ! histone acetylation GO:0016573 26 12 0,000 0,02287079 0,04275611 ! histone methylation GO:0016571 26 12 0,000 0,02287079 0,04272292 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02287079 0,04268977 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02287079 0,04265668 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02287079 0,04262364 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02287079 0,04259065 ! T cell homeostasis GO:0043029 25 12 0,000 0,02287079 0,04255771 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02287079 0,04252482 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02287079 0,04249198 ! spleen development GO:0048536 22 12 0,000 0,02287079 0,0424592 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02287079 0,04242646 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02287079 0,04239377 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02287079 0,04236114 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02287079 0,04232855 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02287079 0,04229602 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02287079 0,04226353 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02287079 0,0422311 ! response to cold GO:0009409 17 12 0,000 0,02287079 0,04219871 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02287079 0,04216637 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02287079 0,04213409 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02475332 0,04556731 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02475332 0,04553248 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02475332 0,04549769 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02475332 0,04546296 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02475332 0,04542828 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02475332 0,04539366 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02475332 0,04535909 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02475332 0,04532457 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02475332 0,0452901 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02475332 0,04525568 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02475332 0,04522132 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02475332 0,04518701 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02475332 0,04515275 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02475332 0,04511854 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02475332 0,04508439 ! methionine metabolic process GO:0006555 27 13 0,000 0,02475332 0,04505029 ! plasma membrane organization GO:0007009 24 13 0,000 0,02475332 0,04501623 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02475332 0,04498223 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02475332 0,04494829 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02475332 0,04491439 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02475332 0,04488054 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02475332 0,04484675 ! response to X-ray GO:0010165 25 13 0,000 0,02475332 0,044813 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02475332 0,04477931 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02475332 0,04474566 ! exocrine system development GO:0035272 32 13 0,000 0,02475332 0,04471207 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02475332 0,04467853 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02475332 0,04464504 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02475332 0,04461159 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02475332 0,0445782 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02475332 0,04454486 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02475332 0,04451157 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02475332 0,04447833 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02475332 0,04444513 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02475332 0,04441199 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02475332 0,0443789 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02475332 0,04434585 ! ribosome assembly GO:0042255 17 13 0,000 0,02475332 0,04431286 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02475332 0,04427991 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02475332 0,04424701 ! chromatin silencing GO:0006342 26 13 0,000 0,02475332 0,04421416 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02475332 0,04418136 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02475332 0,04414861 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02475332 0,04411591 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02475332 0,04408326 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02475332 0,04405065 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02475332 0,04401809 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02475332 0,04398558 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02475332 0,04395312 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02475332 0,04392071 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02475332 0,04388834 ! embryonic placenta development GO:0001892 23 13 0,000 0,02475332 0,04385602 ! insulin secretion GO:0030073 23 13 0,000 0,02475332 0,04382375 ! actin filament polymerization GO:0030041 24 13 0,000 0,02475332 0,04379153 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02475332 0,04375935 ! acrosome reaction GO:0007340 18 13 0,000 0,02475332 0,04372722 ! rRNA transcription GO:0009303 25 14 0,000 0,02663228 0,04701193 ! lactation GO:0007595 26 14 0,000 0,02663228 0,04697747 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02663228 0,04694305 ! reproductive cellular process GO:0048610 20 14 0,000 0,02663228 0,04690869 ! tRNA modification GO:0006400 20 14 0,000 0,02663228 0,04687437 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02663228 0,04684011 ! regulation of S phase GO:0033261 23 14 0,000 0,02663228 0,04680589 ! water transport GO:0006833 21 14 0,000 0,02663228 0,04677173 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02663228 0,04673761 ! non-recombinational repair GO:0000726 25 14 0,000 0,02663228 0,04670355 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02663228 0,04666953 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02663228 0,04663556 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02663228 0,04660165 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02663228 0,04656778 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02663228 0,04653396 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02663228 0,04650019 ! palate development GO:0060021 31 14 0,000 0,02663228 0,04646647 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02663228 0,0464328 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02663228 0,04639918 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02663228 0,0463656 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02663228 0,04633208 ! arginine metabolic process GO:0006525 17 14 0,000 0,02663228 0,0462986 ! regulation of heart rate GO:0002027 24 14 0,000 0,02663228 0,04626517 ! organic alcohol transport GO:0015850 29 14 0,000 0,02663228 0,04623179 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02663228 0,04619846 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02663228 0,04616518 ! embryo implantation GO:0007566 30 14 0,000 0,02663228 0,04613194 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02663228 0,04609875 ! L-amino acid transport GO:0015807 30 14 0,000 0,02663228 0,04606561 ! bone mineralization GO:0030282 17 14 0,000 0,02663228 0,04603252 ! stem cell development GO:0048864 43 14 0,000 0,02663228 0,04599947 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02663228 0,04596647 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02663228 0,04593352 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02663228 0,04590062 ! cerebellum development GO:0021549 21 14 0,000 0,02663228 0,04586776 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02663228 0,04583495 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02663228 0,04580219 ! response to gamma radiation GO:0010332 28 14 0,000 0,02663228 0,04576947 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02663228 0,04573681 ! cofactor transport GO:0051181 26 14 0,000 0,02663228 0,04570418 ! NADP metabolic process GO:0006739 24 14 0,000 0,02663228 0,04567161 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02663228 0,04563908 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02663228 0,04560659 ! intestinal absorption GO:0050892 25 14 0,000 0,02663228 0,04557416 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02663228 0,04554177 ! oxygen transport GO:0015671 21 14 0,000 0,02663228 0,04550942 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02663228 0,04547712 ! male genitalia development GO:0030539 24 14 0,000 0,02663228 0,04544487 ! regulation of axon extension GO:0030516 37 14 0,000 0,02663228 0,04541266 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02663228 0,0453805 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02663228 0,04534838 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02850768 0,04850742 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02850768 0,04847314 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02850768 0,04843891 ! superoxide anion generation GO:0042554 20 15 0,000 0,02850768 0,04840472 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02850768 0,04837059 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02850768 0,0483365 ! copper ion transport GO:0006825 20 15 0,000 0,02850768 0,04830246 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02850768 0,04826847 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02850768 0,04823452 ! sulfate transport GO:0008272 23 15 0,000 0,02850768 0,04820063 ! response to cAMP GO:0051591 22 15 0,000 0,02850768 0,04816678 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02850768 0,04813298 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02850768 0,04809922 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02850768 0,04806551 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02850768 0,04803186 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02850768 0,04799824 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02850768 0,04796468 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02850768 0,04793116 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02850768 0,04789769 ! pituitary gland development GO:0021983 29 15 0,000 0,02850768 0,04786426 ! vesicle coating GO:0006901 33 15 0,000 0,02850768 0,04783089 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02850768 0,04779755 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02850768 0,04776427 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02850768 0,04773103 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02850768 0,04769784 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02850768 0,04766469 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02850768 0,04763159 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02850768 0,04759854 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02850768 0,04756553 ! histone deacetylation GO:0016575 20 15 0,000 0,02850768 0,04753256 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02850768 0,04749965 ! tissue regeneration GO:0042246 26 15 0,000 0,02850768 0,04746677 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02850768 0,04743395 ! water homeostasis GO:0030104 27 15 0,000 0,02850768 0,04740117 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02850768 0,04736843 ! muscle maintenance GO:0046716 26 15 0,000 0,02850768 0,04733574 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02850768 0,0473031 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02850768 0,0472705 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02850768 0,04723794 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02850768 0,04720543 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02850768 0,04717296 ! cell killing GO:0001906 29 15 0,000 0,02850768 0,04714054 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02850768 0,04710817 ! detection of bacterium GO:0016045 18 15 0,000 0,02850768 0,04707583 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02850768 0,04704355 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02850768 0,0470113 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02850768 0,0469791 ! peptide hormone processing GO:0016486 23 15 0,000 0,02850768 0,04694695 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03037954 0,04999533 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03037954 0,04996116 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03037954 0,04992703 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03037954 0,04989295 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03037954 0,04985892 ! bone remodeling GO:0046849 27 16 0,000 0,03037954 0,04982493 ! filopodium assembly GO:0046847 32 16 0,000 0,03037954 0,04979099 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03037954 0,04975709 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03037954 0,04972325 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03037954 0,04968944 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03037954 0,04965569 ! startle response GO:0001964 28 16 0,000 0,03037954 0,04962198 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03037954 0,04958831 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03037954 0,04955469 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03037954 0,04952112 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03037954 0,04948759 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03037954 0,04945411 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03037954 0,04942067 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03037954 0,04938728 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03037954 0,04935393 ! response to osmotic stress GO:0006970 25 16 0,000 0,03037954 0,04932063 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03037954 0,04928737 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03037954 0,04925416 ! fructose metabolic process GO:0006000 25 16 0,000 0,03037954 0,04922099 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03037954 0,04918787 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03037954 0,04915479 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03037954 0,04912175 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03037954 0,04908876 ! axon cargo transport GO:0008088 43 16 0,000 0,03037954 0,04905582 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03037954 0,04902292 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03037954 0,04899006 ! DNA replication initiation GO:0006270 27 16 0,000 0,03037954 0,04895725 ! neuron recognition GO:0008038 35 16 0,000 0,03037954 0,04892448 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03037954 0,04889175 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03037954 0,04885907 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03037954 0,04882643 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03037954 0,04879384 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03037954 0,04876129 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03037954 0,04872878 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03037954 0,04869632 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03037954 0,0486639 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03037954 0,04863152 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03037954 0,04859918 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03037954 0,04856689 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03037954 0,04853464 ! defense response to virus GO:0051607 37 16 0,000 0,03037954 0,04850244 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03224785 0,05145114 ! metencephalon development GO:0022037 30 17 0,000 0,03224785 0,05141705 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03224785 0,051383 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03224785 0,05134899 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03224785 0,05131503 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03224785 0,05128111 ! endothelial cell migration GO:0043542 28 17 0,000 0,03224785 0,05124724 ! inositol metabolic process GO:0006020 28 17 0,000 0,03224785 0,05121341 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03224785 0,05117963 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03224785 0,0511459 ! glial cell development GO:0021782 27 17 0,000 0,03224785 0,0511122 ! limbic system development GO:0021761 36 17 0,000 0,03224785 0,05107855 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03224785 0,05104495 ! adult walking behavior GO:0007628 33 17 0,000 0,03224785 0,05101139 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03224785 0,05097787 ! heart looping GO:0001947 30 17 0,000 0,03224785 0,0509444 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03224785 0,05091097 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03224785 0,05087759 ! myoblast differentiation GO:0045445 45 17 0,000 0,03224785 0,05084425 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03224785 0,05081095 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03224785 0,0507777 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03224785 0,05074449 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03224785 0,05071132 ! glycine metabolic process GO:0006544 28 17 0,000 0,03224785 0,0506782 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03224785 0,05064512 ! NAD metabolic process GO:0019674 29 17 0,000 0,03224785 0,05061208 ! membrane budding GO:0006900 37 17 0,000 0,03224785 0,05057909 ! DNA integration GO:0015074 29 17 0,000 0,03224785 0,05054614 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03224785 0,05051323 ! regulation of protein binding GO:0043393 33 17 0,000 0,03224785 0,05048037 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03224785 0,05044754 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03224785 0,05041477 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03224785 0,05038203 ! genitalia development GO:0048806 30 17 0,000 0,03224785 0,05034933 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03224785 0,05031668 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03224785 0,05028407 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03224785 0,0502515 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03224785 0,05021898 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03224785 0,0501865 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03224785 0,05015406 ! steroid catabolic process GO:0006706 31 17 0,000 0,03224785 0,05012166 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03224785 0,0500893 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03224785 0,05005698 ! gas transport GO:0015669 25 17 0,000 0,03224785 0,05002471 ! organic cation transport GO:0015695 31 17 0,000 0,03224785 0,04999248 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03224785 0,04996029 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03224785 0,04992814 ! microspike assembly GO:0030035 36 17 0,000 0,03224785 0,04989603 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03224785 0,04986396 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03224785 0,04983194 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03411262 0,05267969 ! neuron maturation GO:0042551 42 18 0,000 0,03411262 0,0526459 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03411262 0,05261216 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03411262 0,05257845 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03411262 0,05254479 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03411262 0,05251117 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03411262 0,0524776 ! memory GO:0007613 31 18 0,000 0,03411262 0,05244407 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03411262 0,05241058 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03411262 0,05237713 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03411262 0,05234373 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03411262 0,05231037 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03411262 0,05227705 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03411262 0,05224377 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03411262 0,05221054 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03411262 0,05217735 ! response to retinoic acid GO:0032526 26 18 0,000 0,03411262 0,0521442 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03411262 0,05211109 ! response to fungus GO:0009620 21 18 0,000 0,03411262 0,05207802 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03411262 0,052045 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03411262 0,05201202 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03411262 0,05197908 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03411262 0,05194618 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03411262 0,05191332 ! vitamin transport GO:0051180 27 18 0,000 0,03411262 0,05188051 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03411262 0,05184773 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03411262 0,051815 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03411262 0,05178231 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03411262 0,05174966 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03411262 0,05171705 ! nerve development GO:0021675 28 18 0,000 0,03411262 0,05168449 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03411262 0,05165196 ! protein secretion GO:0009306 39 19 0,000 0,03597386 0,05443592 ! positive regulation of translation GO:0045727 30 19 0,000 0,03597386 0,0544017 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03597386 0,05436753 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03597386 0,0543334 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03597386 0,05429931 ! skin development GO:0043588 36 19 0,000 0,03597386 0,05426527 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03597386 0,05423127 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03597386 0,05419731 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03597386 0,0541634 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03597386 0,05412952 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03597386 0,05409569 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03597386 0,0540619 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03597386 0,05402816 ! cerebral cortex development GO:0021987 36 19 0,000 0,03597386 0,05399445 ! pigmentation during development GO:0048066 41 19 0,000 0,03597386 0,05396079 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03597386 0,05392717 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03597386 0,05389359 ! heme metabolic process GO:0042168 36 19 0,000 0,03597386 0,05386005 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03597386 0,05382656 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03597386 0,05379311 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03597386 0,05375969 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03597386 0,05372632 ! peptide cross-linking GO:0018149 37 19 0,000 0,03597386 0,05369299 ! protein export from nucleus GO:0006611 36 19 0,000 0,03597386 0,05365971 ! heart process GO:0003015 30 19 0,000 0,03597386 0,05362646 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03597386 0,05359326 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03597386 0,05356009 ! visual learning GO:0008542 36 19 0,000 0,03597386 0,05352697 ! cellular pigmentation GO:0033059 36 19 0,000 0,03597386 0,05349389 ! G1 phase GO:0051318 40 19 0,000 0,03597386 0,05346084 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03597386 0,05342784 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03597386 0,05339488 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03597386 0,05336197 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03597386 0,05332909 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03597386 0,05329625 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03597386 0,05326345 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03597386 0,05323069 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03597386 0,05319798 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03597386 0,0531653 ! cilium assembly GO:0042384 37 19 0,000 0,03597386 0,05313266 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03597386 0,05310007 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03783158 0,05580795 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03783158 0,05577376 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03783158 0,0557396 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03783158 0,05570549 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03783158 0,05567142 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03783158 0,05563739 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03783158 0,0556034 ! response to vitamin GO:0033273 31 20 0,000 0,03783158 0,05556946 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03783158 0,05553555 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03783158 0,05550169 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03783158 0,05546787 ! response to alkaloid GO:0043279 38 20 0,000 0,03783158 0,05543409 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03783158 0,05540035 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03783158 0,05536665 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03783158 0,05533299 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03783158 0,05529937 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03783158 0,0552658 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03783158 0,05523226 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03783158 0,05519877 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03783158 0,05516532 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03783158 0,0551319 ! body fluid secretion GO:0007589 31 20 0,000 0,03783158 0,05509853 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03783158 0,0550652 ! peptide secretion GO:0002790 35 20 0,000 0,03783158 0,05503191 ! stem cell differentiation GO:0048863 53 20 0,000 0,03783158 0,05499865 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03783158 0,05496544 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03783158 0,05493227 ! sensory perception of pain GO:0019233 30 20 0,000 0,03783158 0,05489914 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03783158 0,05486605 ! diencephalon development GO:0021536 34 20 0,000 0,03783158 0,05483299 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03783158 0,05479998 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03783158 0,05476701 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03783158 0,05473408 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03783158 0,05470118 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03783158 0,05466833 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03783158 0,05463552 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03783158 0,05460274 ! regulation of glucose import GO:0046324 29 20 0,000 0,03783158 0,05457001 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03783158 0,05453731 ! actin filament-based movement GO:0030048 43 20 0,000 0,03783158 0,05450465 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03783158 0,05447204 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03783158 0,05443946 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03783158 0,05440692 ! negative regulation of translation GO:0017148 29 20 0,000 0,03783158 0,05437442 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03783158 0,05434195 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03783158 0,05430953 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03968577 0,05693737 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03968577 0,05690344 ! hormone secretion GO:0046879 38 21 0,000 0,03968577 0,05686955 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03968577 0,0568357 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03968577 0,05680189 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03968577 0,05676811 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03968577 0,05673438 ! axis specification GO:0009798 38 21 0,000 0,03968577 0,05670069 ! ovarian follicle development GO:0001541 35 21 0,000 0,03968577 0,05666704 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03968577 0,05663343 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03968577 0,05659986 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03968577 0,05656633 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03968577 0,05653284 ! cell aging GO:0007569 44 21 0,000 0,03968577 0,05649939 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03968577 0,05646598 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03968577 0,05643261 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03968577 0,05639927 ! cytolysis GO:0019835 24 21 0,000 0,03968577 0,05636598 ! vasodilation GO:0042311 39 21 0,000 0,03968577 0,05633273 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03968577 0,05629951 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03968577 0,05626633 ! oogenesis GO:0048477 36 21 0,000 0,03968577 0,0562332 ! DNA modification GO:0006304 34 21 0,000 0,03968577 0,0562001 ! collagen fibril organization GO:0030199 59 21 0,000 0,03968577 0,05616704 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03968577 0,05613402 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03968577 0,05610104 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03968577 0,0560681 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03968577 0,05603519 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03968577 0,05600233 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03968577 0,0559695 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03968577 0,05593671 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03968577 0,05590396 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03968577 0,05587125 ! collagen catabolic process GO:0030574 28 21 0,000 0,03968577 0,05583858 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03968577 0,05580594 ! gut development GO:0048565 39 21 0,000 0,03968577 0,05577335 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04153646 0,05834017 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04153646 0,05830614 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04153646 0,05827214 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04153646 0,05823818 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04153646 0,05820426 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04153646 0,05817038 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04153646 0,05813654 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04153646 0,05810274 ! regeneration GO:0031099 41 22 0,000 0,04153646 0,05806898 ! keratinization GO:0031424 28 22 0,000 0,04153646 0,05803526 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04153646 0,05800158 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04153646 0,05796793 ! sensory perception of taste GO:0050909 28 22 0,000 0,04153646 0,05793433 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04153646 0,05790076 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04153646 0,05786724 ! vacuolar transport GO:0007034 36 22 0,000 0,04153646 0,05783375 ! lysosome organization GO:0007040 41 22 0,000 0,04153646 0,0578003 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04153646 0,05776689 ! fucose metabolic process GO:0006004 39 22 0,000 0,04153646 0,05773352 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04153646 0,05770018 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04153646 0,05766689 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04153646 0,05763363 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04153646 0,05760041 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04153646 0,05756723 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04153646 0,05753409 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04153646 0,05750099 ! sarcomere organization GO:0045214 30 22 0,000 0,04153646 0,05746792 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04153646 0,0574349 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04153646 0,05740191 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04153646 0,05736895 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04153646 0,05733604 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04153646 0,05730316 ! protein stabilization GO:0050821 39 22 0,000 0,04153646 0,05727033 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04338364 0,05978295 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04338364 0,05974873 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04338364 0,05971455 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04338364 0,05968041 ! gluconeogenesis GO:0006094 33 23 0,000 0,04338364 0,0596463 ! viral genome replication GO:0019079 41 23 0,000 0,04338364 0,05961224 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04338364 0,05957822 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04338364 0,05954423 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04338364 0,05951028 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04338364 0,05947637 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04338364 0,0594425 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04338364 0,05940867 ! visual behavior GO:0007632 42 23 0,000 0,04338364 0,05937488 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04338364 0,05934112 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,04338364 0,05930741 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04338364 0,05927373 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04338364 0,05924009 ! peroxisome organization GO:0007031 37 23 0,000 0,04338364 0,05920649 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04338364 0,05917292 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04338364 0,0591394 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04338364 0,05910591 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04338364 0,05907246 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04338364 0,05903905 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04338364 0,05900567 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04338364 0,05897234 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04338364 0,05893904 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04338364 0,05890577 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04338364 0,05887255 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04338364 0,05883936 ! fatty acid transport GO:0015908 44 23 0,000 0,04338364 0,05880622 ! platelet activation GO:0030168 37 23 0,000 0,04338364 0,0587731 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04338364 0,05874003 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04338364 0,05870699 ! hormone transport GO:0009914 40 23 0,000 0,04338364 0,05867399 ! cell-cell recognition GO:0009988 25 23 0,000 0,04338364 0,05864103 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04338364 0,0586081 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04338364 0,05857522 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04338364 0,05854236 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04338364 0,05850955 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04338364 0,05847677 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04522732 0,06092773 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,04522732 0,06089364 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04522732 0,06085958 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04522732 0,06082556 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04522732 0,06079158 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04522732 0,06075764 ! spinal cord development GO:0021510 47 24 0,000 0,04522732 0,06072373 ! vacuole organization GO:0007033 43 24 0,000 0,04522732 0,06068987 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04522732 0,06065604 ! digestive system process GO:0022600 39 24 0,000 0,04522732 0,06062225 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04522732 0,06058849 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04522732 0,06055478 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04522732 0,0605211 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04522732 0,06048745 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04522732 0,06045385 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,04522732 0,06042028 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04522732 0,06038675 ! pallium development GO:0021543 49 24 0,000 0,04522732 0,06035326 ! pentose metabolic process GO:0019321 35 24 0,000 0,04522732 0,06031981 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04522732 0,06028639 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04522732 0,06025301 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04522732 0,06021966 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04522732 0,06018636 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04522732 0,06015308 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04522732 0,06011985 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04522732 0,06008665 ! regulation of amine transport GO:0051952 40 24 0,000 0,04522732 0,06005349 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,04706751 0,06246245 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,04706751 0,06242802 ! myelination GO:0042552 45 25 0,000 0,04706751 0,06239362 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,04706751 0,06235927 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,04706751 0,06232495 ! phototransduction GO:0007602 33 25 0,000 0,04706751 0,06229066 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,04706751 0,06225642 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,04706751 0,06222221 ! sperm motility GO:0030317 31 25 0,000 0,04706751 0,06218804 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,04706751 0,06215391 ! receptor metabolic process GO:0043112 46 25 0,000 0,04706751 0,06211982 ! chromosome condensation GO:0030261 45 25 0,000 0,04706751 0,06208576 ! response to starvation GO:0042594 42 25 0,000 0,04706751 0,06205174 ! osteoblast differentiation GO:0001649 60 25 0,000 0,04706751 0,06201776 ! neural crest cell development GO:0014032 54 25 0,000 0,04706751 0,06198381 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,04706751 0,0619499 ! negative regulation of cell development GO:0010721 73 25 0,000 0,04706751 0,06191603 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,04706751 0,0618822 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,04706751 0,0618484 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,04706751 0,06181464 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,04706751 0,06178092 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,04706751 0,06174723 ! immunoglobulin production GO:0002377 55 25 0,000 0,04706751 0,06171358 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,04706751 0,06167997 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,04706751 0,06164639 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,04706751 0,06161285 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,04706751 0,06157935 ! telomere organization GO:0032200 43 25 0,000 0,04706751 0,06154588 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,04706751 0,06151245 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,04706751 0,06147906 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04890421 0,06384348 ! embryonic pattern specification GO:0009880 44 26 0,000 0,04890421 0,06380886 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,04890421 0,06377427 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,04890421 0,06373973 ! initiation of viral infection GO:0019059 57 26 0,000 0,04890421 0,06370522 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04890421 0,06367074 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04890421 0,06363631 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04890421 0,06360191 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04890421 0,06356755 ! molting cycle process GO:0022404 50 26 0,000 0,04890421 0,06353323 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04890421 0,06349894 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,04890421 0,06346469 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04890421 0,06343048 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04890421 0,0633963 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,04890421 0,06336216 GO:0045936|negative regulation of phosphate metabolic process, ! response to estradiol stimulus GO:0032355 40 26 0,000 0,04890421 0,06332806 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,04890421 0,06329399 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04890421 0,06325997 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,04890421 0,06322597 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,04890421 0,06319202 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04890421 0,0631581 ! blastocyst development GO:0001824 49 26 0,000 0,04890421 0,06312421 ! leukocyte proliferation GO:0070661 52 26 0,000 0,04890421 0,06309037 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04890421 0,06305656 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04890421 0,06302278 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,05073744 0,06535025 ! neuron fate commitment GO:0048663 48 27 0,000 0,05073744 0,06531529 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05073744 0,06528036 ! iron ion transport GO:0006826 59 27 0,000 0,05073744 0,06524547 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05073744 0,06521062 ! protein amino acid acylation GO:0043543 55 27 0,000 0,05073744 0,0651758 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05073744 0,06514102 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05073744 0,06510628 ! fat cell differentiation GO:0045444 50 27 0,000 0,05073744 0,06507157 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05073744 0,06503691 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,05073744 0,06500228 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05073744 0,06496768 ! autophagy GO:0006914 41 27 0,000 0,05073744 0,06493312 ! male gonad development GO:0008584 44 27 0,000 0,05073744 0,0648986 ! response to toxin GO:0009636 47 27 0,000 0,05073744 0,06486412 ! primary neural tube formation GO:0014020 51 27 0,000 0,05073744 0,06482967 ! base-excision repair GO:0006284 41 27 0,000 0,05073744 0,06479526 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05073744 0,06476089 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05073744 0,06472655 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05073744 0,06469225 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05073744 0,06465798 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05073744 0,06462375 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05073744 0,06458956 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05073744 0,06455541 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05073744 0,06452129 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05256719 0,06681281 ! circadian rhythm GO:0007623 50 28 0,000 0,05256719 0,06677754 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05256719 0,0667423 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05256719 0,0667071 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05256719 0,06667193 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05256719 0,0666368 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05256719 0,06660171 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05256719 0,06656666 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05256719 0,06653164 ! synaptogenesis GO:0007416 42 28 0,000 0,05256719 0,06649666 ! lipid oxidation GO:0034440 43 28 0,000 0,05256719 0,06646172 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05256719 0,06642681 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05256719 0,06639195 ! translational initiation GO:0006413 65 29 0,000 0,05439347 0,06866249 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,05439347 0,06862648 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,05439347 0,06859051 ! regulation of pH GO:0006885 43 29 0,000 0,05439347 0,06855458 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,05439347 0,06851869 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,05439347 0,06848284 ! catechol metabolic process GO:0009712 54 29 0,000 0,05439347 0,06844702 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,05439347 0,06841124 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,05439347 0,0683755 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,05439347 0,06833979 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,05439347 0,06830412 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,05439347 0,06826849 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,05439347 0,0682329 ! cell fate determination GO:0001709 60 29 0,000 0,05439347 0,06819734 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,05439347 0,06816182 ! detection of light stimulus GO:0009583 38 29 0,000 0,05439347 0,06812634 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,05439347 0,06809089 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,05439347 0,06805549 ! tissue homeostasis GO:0001894 48 29 0,000 0,05439347 0,06802011 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,0562163 0,07026307 ! zinc ion transport GO:0006829 45 30 0,000 0,0562163 0,07022659 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0562163 0,07019015 ! cell junction assembly GO:0034329 78 30 0,000 0,0562163 0,07015374 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0562163 0,07011738 ! acute-phase response GO:0006953 49 30 0,000 0,0562163 0,07008104 ! myofibril assembly GO:0030239 47 30 0,000 0,0562163 0,07004475 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0562163 0,0700085 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,0562163 0,06997228 ! phospholipid transport GO:0015914 51 30 0,000 0,0562163 0,0699361 ! ensheathment of neurons GO:0007272 57 30 0,000 0,0562163 0,06989996 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0562163 0,06986385 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0562163 0,06982778 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,0562163 0,06979175 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0562163 0,06975576 ! eye morphogenesis GO:0048592 60 30 0,000 0,0562163 0,0697198 ! regulation of B cell activation GO:0050864 50 30 0,000 0,0562163 0,06968388 ! response to heat GO:0009408 50 30 0,000 0,0562163 0,069648 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05803567 0,07186507 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05803567 0,0718281 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05803567 0,07179117 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05803567 0,07175428 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05803567 0,07171743 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05803567 0,07168061 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05803567 0,07164383 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05803567 0,07160709 ! ovulation cycle process GO:0022602 49 31 0,000 0,05803567 0,07157039 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05803567 0,07153372 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,05803567 0,0714971 ! peptide transport GO:0015833 55 31 0,000 0,05803567 0,0714605 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05803567 0,07142395 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05803567 0,07138744 ! mesoderm formation GO:0001707 69 31 0,000 0,05803567 0,07135096 ! natural killer cell activation GO:0030101 45 31 0,000 0,05803567 0,07131452 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,05803567 0,07127811 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05803567 0,07124175 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05803567 0,07120542 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,05803567 0,07116913 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05803567 0,07113287 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0598516 0,07332125 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0598516 0,07328394 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0598516 0,07324666 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0598516 0,07320943 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0598516 0,07317223 ! spliceosome assembly GO:0000245 67 32 0,000 0,0598516 0,07313507 ! spindle organization GO:0007051 46 32 0,000 0,0598516 0,07309794 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0598516 0,07306085 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0598516 0,0730238 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0598516 0,07298679 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0598516 0,07294982 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0598516 0,07291288 ! muscle cell development GO:0055001 49 32 0,000 0,0598516 0,07287598 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0598516 0,07283912 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0598516 0,0728023 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0598516 0,07276551 ! ovulation cycle GO:0042698 51 32 0,000 0,0598516 0,07272876 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0598516 0,07269205 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0598516 0,07265537 ! hindbrain development GO:0030902 61 32 0,000 0,0598516 0,07261873 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0598516 0,07258213 ! gene silencing GO:0016458 65 32 0,000 0,0598516 0,07254556 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06166408 0,07470482 ! post-embryonic development GO:0009791 69 33 0,000 0,06166408 0,07466723 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,06166408 0,07462967 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06166408 0,07459215 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,06166408 0,07455466 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06166408 0,07451722 ! formation of primary germ layer GO:0001704 72 33 0,000 0,06166408 0,07447981 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,06166408 0,07444244 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06166408 0,07440511 ! adult locomotory behavior GO:0008344 59 33 0,000 0,06166408 0,07436781 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,06166408 0,07433055 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06166408 0,07429333 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,06347313 0,07643461 ! glial cell differentiation GO:0010001 63 34 0,000 0,06347313 0,07639638 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,06347313 0,07635818 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,06347313 0,07632002 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,06347313 0,0762819 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,06347313 0,07624381 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,06347313 0,07620577 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,06347313 0,07616776 ! mismatch repair GO:0006298 46 34 0,000 0,06347313 0,07612979 ! spermatid development GO:0007286 63 34 0,000 0,06347313 0,07609186 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,06347313 0,07605396 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,06347313 0,07601611 ! placenta development GO:0001890 53 34 0,000 0,06347313 0,07597829 ! regulation of muscle development GO:0048634 70 35 0,000 0,06527876 0,07810079 ! negative regulation of secretion GO:0051048 63 35 0,000 0,06527876 0,07806197 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,06527876 0,07802319 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,06527876 0,07798445 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,06527876 0,07794575 ! odontogenesis GO:0042476 66 35 0,000 0,06527876 0,07790709 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,06527876 0,07786846 ! female gonad development GO:0008585 58 35 0,000 0,06527876 0,07782987 ! telencephalon development GO:0021537 68 35 0,000 0,06527876 0,07779133 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,06527876 0,07775282 ! cytokine production GO:0001816 59 35 0,000 0,06527876 0,07771434 ! neural tube formation GO:0001841 67 35 0,000 0,06527876 0,07767591 ! vesicle localization GO:0051648 64 35 0,000 0,06527876 0,07763751 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,06708096 0,07974149 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,06708096 0,07970212 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,06708096 0,07966278 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,06708096 0,07962348 ! cell junction organization GO:0034330 86 36 0,000 0,06708096 0,07958421 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,06708096 0,07954499 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,06708096 0,07950581 ! positive regulation of cell development GO:0010720 80 36 0,000 0,06708096 0,07946666 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,06708096 0,07942755 ! regulation of proteolysis GO:0030162 72 36 0,000 0,06708096 0,07938848 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,06708096 0,07934945 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,06708096 0,07931046 ! aerobic respiration GO:0009060 55 36 0,000 0,06708096 0,07927151 ! embryonic organ development GO:0048568 57 36 0,000 0,06708096 0,07923259 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,06708096 0,07919371 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,06708096 0,07915487 ! RNA export from nucleus GO:0006405 56 37 0,000 0,06887974 0,08123758 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,06887974 0,08119778 ! meiosis I GO:0007127 65 37 0,000 0,06887974 0,08115801 ! sister chromatid segregation GO:0000819 58 37 0,000 0,06887974 0,08111829 ! actomyosin structure organization GO:0031032 62 37 0,000 0,06887974 0,0810786 ! organic anion transport GO:0015711 68 37 0,000 0,06887974 0,08103896 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,06887974 0,08099935 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,06887974 0,08095978 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,06887974 0,08092025 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,06887974 0,08088075 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,06887974 0,0808413 ! pigment metabolic process GO:0042440 80 37 0,000 0,06887974 0,08080188 ! spermatid differentiation GO:0048515 66 37 0,000 0,06887974 0,08076251 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,07067512 0,08282725 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,07067512 0,08278693 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,07067512 0,08274664 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,07067512 0,08270639 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,07067512 0,08266619 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,07067512 0,08262602 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,07067512 0,08258589 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,07067512 0,0825458 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,07067512 0,08250575 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,07067512 0,08246573 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,07067512 0,08242576 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,07067512 0,08238583 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,07067512 0,08234593 ! mRNA catabolic process GO:0006402 71 39 0,000 0,0724671 0,08439295 ! learning GO:0007612 77 39 0,000 0,0724671 0,08435212 ! ear morphogenesis GO:0042471 60 39 0,000 0,0724671 0,08431133 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,0724671 0,08427058 ! segmentation GO:0035282 67 39 0,000 0,0724671 0,08422987 ! ion transmembrane transport GO:0034220 66 39 0,000 0,0724671 0,0841892 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,0724671 0,08414857 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,0724671 0,08410798 ! RNA modification GO:0009451 57 39 0,000 0,0724671 0,08406742 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,0724671 0,08402691 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,07425568 0,08605933 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,07425568 0,08601789 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,07425568 0,0859765 ! feeding behavior GO:0007631 59 40 0,000 0,07425568 0,08593514 ! negative regulation of binding GO:0051100 72 40 0,000 0,07425568 0,08589383 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,07425568 0,08585255 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,07425568 0,08581132 ! maintenance of protein location GO:0045185 91 40 0,000 0,07425568 0,08577012 ! cytokinesis GO:0000910 72 40 0,000 0,07425568 0,08572896 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,07604087 0,08774788 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,07604087 0,08770582 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,07604087 0,08766379 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,07604087 0,08762181 ! gliogenesis GO:0042063 88 41 0,000 0,07604087 0,08757986 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,07604087 0,08753796 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,07604087 0,08749609 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,07604087 0,08745427 ! female gamete generation GO:0007292 61 41 0,000 0,07604087 0,08741248 ! polyol metabolic process GO:0019751 66 41 0,000 0,07604087 0,08737074 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,07604087 0,08732904 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,07782268 0,08933271 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,07782268 0,08929011 ! regulation of tube size GO:0035150 71 42 0,000 0,07782268 0,08924755 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,07782268 0,08920503 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,07782268 0,08916255 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,07782268 0,08912011 ! neuron migration GO:0001764 79 42 0,000 0,07782268 0,08907772 ! regulation of protein secretion GO:0050708 71 42 0,000 0,07782268 0,08903536 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,07782268 0,08899304 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,07960111 0,0909835 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,07960111 0,09094029 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,07960111 0,09089713 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,07960111 0,09085401 ! glucose transport GO:0015758 65 43 0,000 0,07960111 0,09081093 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,07960111 0,0907679 ! neural tube development GO:0021915 77 43 0,000 0,07960111 0,0907249 ! striated muscle contraction GO:0006941 77 43 0,000 0,07960111 0,09068194 ! phagocytosis GO:0006909 90 43 0,000 0,07960111 0,09063903 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,07960111 0,09059615 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,08137617 0,0925726 ! hexose transport GO:0008645 67 44 0,000 0,08137617 0,09252885 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,08137617 0,09248515 ! male sex differentiation GO:0046661 76 44 0,000 0,08137617 0,09244148 ! double-strand break repair GO:0006302 81 44 0,000 0,08137617 0,09239785 ! biopolymer methylation GO:0043414 84 44 0,000 0,08137617 0,09235427 ! B cell differentiation GO:0030183 107 44 0,000 0,08137617 0,09231073 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,08137617 0,09226723 ! developmental growth GO:0048589 82 44 0,000 0,08137617 0,09222377 ! maintenance of location in cell GO:0051651 97 44 0,000 0,08137617 0,09218035 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,08314786 0,09414294 ! glycolysis GO:0006096 65 45 0,000 0,08314786 0,09409866 ! leukocyte migration GO:0050900 68 45 0,000 0,08314786 0,09405442 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,08314786 0,09401022 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,08314786 0,09396606 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,08314786 0,09392195 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,08314786 0,09387788 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,08314786 0,09383384 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,08314786 0,09378985 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,08314786 0,0937459 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0849162 0,09569479 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0849162 0,09564999 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,0849162 0,09560523 ! pigmentation GO:0043473 100 46 0,000 0,0849162 0,09556051 ! positive regulation of defense response GO:0031349 76 47 0,000 0,08668118 0,09750113 ! response to calcium ion GO:0051592 81 47 0,000 0,08668118 0,09745557 ! endosome transport GO:0016197 108 47 0,000 0,08668118 0,09741005 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,08668118 0,09736458 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,08668118 0,09731914 ! JNK cascade GO:0007254 91 47 0,000 0,08668118 0,09727375 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,08668118 0,0972284 ! methylation GO:0032259 90 47 0,000 0,08668118 0,0971831 ! mitochondrial transport GO:0006839 82 48 0,000 0,08844282 0,09911198 ! Notch signaling pathway GO:0007219 96 48 0,000 0,08844282 0,09906584 ! cellular component disassembly GO:0022411 86 48 0,000 0,08844282 0,09901974 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,08844282 0,09897369 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,08844282 0,09892767 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,08844282 0,0988817 ! activation of caspase activity GO:0006919 84 48 0,000 0,08844282 0,09883578 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,08844282 0,09878989 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,08844282 0,09874405 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,08844282 0,09869825 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,09020112 0,10061377 ! regulation of action potential GO:0001508 95 49 0,000 0,09020112 0,10056714 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,09020112 0,10052056 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,09020112 0,10047403 ! regulation of ion transport GO:0043269 77 49 0,000 0,09020112 0,10042753 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,09020112 0,10038108 ! peptide metabolic process GO:0006518 76 49 0,000 0,09020112 0,10033467 ! response to temperature stimulus GO:0009266 76 49 0,000 0,09020112 0,10028831 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,09020112 0,10024198 ! endocrine system development GO:0035270 104 49 0,000 0,09020112 0,10019571 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,09020112 0,10014947 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,09020112 0,10010327 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,09020112 0,10005712 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,09020112 0,10001101 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,09195609 0,10190988 ! neuromuscular process GO:0050905 99 50 0,000 0,09195609 0,10186296 ! regulation of ossification GO:0030278 117 50 0,000 0,09195609 0,10181608 ! inner ear development GO:0048839 79 50 0,000 0,09195609 0,10176925 ! histone modification GO:0016570 91 50 0,000 0,09195609 0,10172246 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,09195609 0,10167571 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,09195609 0,10162901 ! positive regulation of binding GO:0051099 78 51 0,000 0,09370773 0,10351735 ! viral infectious cycle GO:0019058 99 51 0,000 0,09370773 0,10346984 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,09370773 0,10342238 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,09370773 0,10337496 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,09370773 0,10332759 ! excretion GO:0007588 83 51 0,000 0,09370773 0,10328025 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,09370773 0,10323296 ! chromatin remodeling GO:0006338 109 51 0,000 0,09370773 0,10318572 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,09370773 0,10313851 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,09370773 0,10309135 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,09370773 0,10304424 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 0,000 0,09545605 0,1049188 ! covalent chromatin modification GO:0016569 101 52 0,000 0,09545605 0,10487089 ! amino acid activation GO:0043038 92 52 0,000 0,09545605 0,10482302 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,09545605 0,1047752 ! synapse organization GO:0050808 85 52 0,000 0,09545605 0,10472743 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,09720105 0,10659331 ! RNA catabolic process GO:0006401 93 53 0,000 0,09720105 0,10654475 ! regulation of translational initiation GO:0006446 82 53 0,000 0,09720105 0,10649623 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,09720105 0,10644776 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,09720105 0,10639933 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,09720105 0,10635094 ! cell maturation GO:0048469 100 53 0,000 0,09720105 0,1063026 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,09720105 0,10625431 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,09894275 0,1081091 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,09894275 0,10806003 ! cell recognition GO:0008037 85 54 0,000 0,09894275 0,108011 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,09894275 0,10796202 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,09894275 0,10791308 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,09894275 0,10786418 ! chloride transport GO:0006821 90 55 0,000 0,10068114 0,10970961 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,10068114 0,10965995 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,10068114 0,10961033 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,10068114 0,10956075 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,10068114 0,10951122 ! aging GO:0007568 103 55 0,000 0,10068114 0,10946174 ! gastrulation GO:0007369 112 55 0,000 0,10068114 0,10941229 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,10068114 0,1093629 ! RNA elongation GO:0006354 79 55 0,000 0,10068114 0,10931355 ! nuclear export GO:0051168 97 55 0,000 0,10068114 0,10926424 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,10068114 0,10921498 ! regulation of actin filament length GO:0030832 105 56 0,000 0,10241624 0,11104708 ! sensory perception of smell GO:0007608 80 56 0,000 0,10241624 0,11099706 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,10241624 0,11094708 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,10241624 0,11089715 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,10241624 0,11084726 ! proton transport GO:0015992 94 56 0,000 0,10241624 0,11079742 ! muscle fiber development GO:0048747 112 57 0,000 0,10414804 0,11262031 ! maintenance of location GO:0051235 118 57 0,000 0,10414804 0,11256972 ! hydrogen transport GO:0006818 97 58 0,000 0,10587657 0,11438663 ! regulation of endocytosis GO:0030100 91 58 0,000 0,10587657 0,11433529 ! adult behavior GO:0030534 99 58 0,000 0,10587657 0,11428399 ! positive regulation of secretion GO:0051047 95 59 0,000 0,10760181 0,11609415 ! regulation of cellular component size GO:0032535 109 59 0,000 0,10760181 0,11604212 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,10760181 0,11599013 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,10760181 0,11593818 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,10760181 0,11588629 ! DNA catabolic process GO:0006308 86 59 0,000 0,10760181 0,11583443 ! establishment of organelle localization GO:0051656 109 59 0,000 0,10760181 0,11578263 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,10932379 0,11758294 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,10932379 0,1175304 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,10932379 0,11747791 ! regulation of heart contraction GO:0008016 110 60 0,000 0,10932379 0,11742546 ! camera-type eye development GO:0043010 116 60 0,000 0,10932379 0,11737306 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1110425 0,11916514 ! mesoderm development GO:0007498 119 61 0,000 0,1110425 0,11911201 ! tRNA processing GO:0008033 89 61 0,000 0,1110425 0,11905893 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1110425 0,1190059 ! ear development GO:0043583 103 62 0,000 0,11275794 0,12079057 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,11275794 0,12073681 ! gonad development GO:0008406 98 62 0,000 0,11275794 0,1206831 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,11447014 0,12246116 ! detection of external stimulus GO:0009581 91 63 0,000 0,11447014 0,12240674 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,11447014 0,12235236 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,11617909 0,12412384 ! cell redox homeostasis GO:0045454 102 64 0,000 0,11617909 0,12406875 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,11617909 0,1240137 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,11617909 0,12395871 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,11617909 0,12390376 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,1178848 0,12566718 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,1178848 0,12561152 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,1178848 0,12555592 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,1178848 0,12550036 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,11958727 0,12725651 ! actin filament organization GO:0007015 148 66 0,000 0,11958727 0,12720025 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,11958727 0,12714404 ! extracellular matrix organization GO:0030198 133 66 0,000 0,11958727 0,12708788 ! secondary metabolic process GO:0019748 116 66 0,000 0,11958727 0,12703177 ! developmental maturation GO:0021700 116 66 0,000 0,11958727 0,12697571 ! cell projection assembly GO:0030031 120 66 0,000 0,11958727 0,1269197 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,12128651 0,12866638 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,12128651 0,12860967 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,12128651 0,12855301 ! chromosome segregation GO:0007059 113 67 0,000 0,12128651 0,12849641 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,12128651 0,12843985 ! hexose catabolic process GO:0019320 104 67 0,000 0,12128651 0,12838334 ! activation of immune response GO:0002253 105 67 0,000 0,12128651 0,12832689 ! amino acid transport GO:0006865 125 68 0,000 0,12298253 0,13006416 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,12298253 0,13000701 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,12298253 0,12994992 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,12298253 0,12989287 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,12298253 0,12983588 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,12467533 0,13156528 ! negative regulation of cell size GO:0045792 134 69 0,000 0,12467533 0,1315076 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,12467533 0,13144998 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,12467533 0,1313924 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,12467533 0,13133487 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,12467533 0,13127739 ! antigen processing and presentation GO:0019882 104 69 0,000 0,12467533 0,13121997 ! appendage morphogenesis GO:0035107 135 70 0,000 0,12636492 0,1329401 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,12805131 0,13465535 ! reproductive structure development GO:0048608 113 71 0,000 0,12805131 0,13459653 ! appendage development GO:0048736 136 71 0,000 0,12805131 0,13453775 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,12805131 0,13447903 ! B cell activation GO:0042113 160 71 0,000 0,12805131 0,13442035 ! acute inflammatory response GO:0002526 113 72 0,000 0,12973449 0,13612786 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,12973449 0,13606852 ! carbohydrate transport GO:0008643 110 72 0,000 0,12973449 0,13600923 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,12973449 0,13595 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,12973449 0,13589081 ! learning or memory GO:0007611 147 73 0,000 0,13141449 0,13759063 ! regulation of blood pressure GO:0008217 125 73 0,000 0,13141449 0,13753078 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,13141449 0,13747098 ! axon guidance GO:0007411 139 73 0,000 0,13141449 0,13741124 ! fertilization GO:0009566 90 73 0,000 0,13141449 0,13735155 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,13309129 0,13904371 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,13309129 0,13898336 ! neurotransmitter transport GO:0006836 123 74 0,000 0,13309129 0,13892306 ! meiosis GO:0007126 121 74 0,000 0,13309129 0,13886282 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,13309129 0,13880262 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,13309129 0,13874248 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,13309129 0,1386824 ! eye development GO:0001654 143 74 0,000 0,13309129 0,13862236 ! organelle localization GO:0051640 136 74 0,000 0,13309129 0,13856238 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,13476492 0,14024411 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,13476492 0,14018348 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,13476492 0,1401229 ! meiotic cell cycle GO:0051321 122 75 0,000 0,13476492 0,14006237 ! rhythmic process GO:0048511 128 75 0,000 0,13476492 0,1400019 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,13643537 0,14167609 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,13643537 0,14161497 ! defense response to bacterium GO:0042742 89 76 0,000 0,13643537 0,1415539 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,13643537 0,14149289 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,13643537 0,14143192 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,13810265 0,14309861 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,13810265 0,14303701 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,13810265 0,14297546 ! blood coagulation GO:0007596 146 78 0,000 0,13976676 0,14463606 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,13976676 0,14457387 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,13976676 0,14451175 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,13976676 0,14444967 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,14142772 0,14610352 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,14142772 0,14604081 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,14142772 0,14597816 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,14142772 0,14591557 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,14142772 0,14585302 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,14308553 0,14749948 ! response to metal ion GO:0010038 140 80 0,000 0,14308553 0,14743631 ! muscle cell differentiation GO:0042692 159 80 0,000 0,14308553 0,14737319 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,14308553 0,14731013 ! protein import into nucleus GO:0006606 158 80 0,000 0,14308553 0,14724713 ! inorganic anion transport GO:0015698 138 80 0,000 0,14308553 0,14718417 ! digestion GO:0007586 112 81 0,000 0,14474019 0,1488226 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,14474019 0,14875903 ! nuclear import GO:0051170 161 81 0,000 0,14474019 0,14869551 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,14474019 0,14863205 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,14639171 0,15026384 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,14639171 0,15019977 ! response to drug GO:0042493 143 82 0,000 0,14639171 0,15013574 ! response to nutrient GO:0007584 125 82 0,000 0,14639171 0,15007177 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,14639171 0,15000786 ! regulation of lyase activity GO:0051339 160 83 0,000 0,1480401 0,15163238 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,14968535 0,15325232 ! hemostasis GO:0007599 158 84 0,000 0,14968535 0,15318714 ! negative regulation of transport GO:0051051 153 84 0,000 0,14968535 0,15312201 ! negative regulation of growth GO:0045926 155 84 0,000 0,14968535 0,15305693 ! regulation of ligase activity GO:0051340 142 84 0,000 0,14968535 0,15299191 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,14968535 0,15292695 ! response to unfolded protein GO:0006986 131 85 0,000 0,15132749 0,15453902 ! nucleosome assembly GO:0006334 122 85 0,000 0,15132749 0,15447346 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,15132749 0,15440795 ! amine biosynthetic process GO:0009309 138 86 0,000 0,15296651 0,15601417 ! response to inorganic substance GO:0010035 153 86 0,000 0,15296651 0,15594806 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,15296651 0,15588201 ! chromatin assembly GO:0031497 124 86 0,000 0,15296651 0,15581601 ! mitochondrion organization GO:0007005 148 86 0,000 0,15296651 0,15575007 ! alcohol catabolic process GO:0046164 130 86 0,000 0,15296651 0,15568419 ! amine transport GO:0015837 155 86 0,000 0,15296651 0,15561836 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,15460241 0,15721615 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,15460241 0,15714973 ! protein localization in nucleus GO:0034504 176 87 0,000 0,15460241 0,15708337 ! cellular respiration GO:0045333 135 88 0,000 0,15623522 0,15867536 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,15623522 0,15860841 ! regulation of DNA binding GO:0051101 155 88 0,000 0,15623522 0,15854152 ! regulation of neurological system process GO:0031644 148 88 0,000 0,15623522 0,15847468 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,15623522 0,15840789 ! cellular defense response GO:0006968 114 89 0,000 0,15786492 0,15999284 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,15786492 0,15992547 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,15949153 0,16150531 ! sex differentiation GO:0007548 145 90 0,000 0,15949153 0,16143737 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,15949153 0,16136948 ! sterol metabolic process GO:0016125 152 91 0,000 0,16111505 0,1629436 ! response to protein stimulus GO:0051789 149 91 0,000 0,16111505 0,16287513 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,16111505 0,16280673 ! regulation of defense response GO:0031347 149 92 0,000 0,16273549 0,16437514 ! nucleosome organization GO:0034728 138 92 0,000 0,16273549 0,16430617 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,16273549 0,16423725 ! vitamin metabolic process GO:0006766 139 92 0,000 0,16273549 0,16416838 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,16435286 0,1657305 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,16435286 0,16566107 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,16435286 0,1655917 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,16596715 0,16714816 ! female pregnancy GO:0007565 164 94 0,000 0,16596715 0,16707823 ! transcription initiation GO:0006352 153 94 0,000 0,16596715 0,16700835 ! forebrain development GO:0030900 188 95 0,000 0,16757838 0,16855919 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,16757838 0,16848875 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,16918655 0,1700346 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,16918655 0,1699636 ! positive regulation of immune response GO:0050778 156 96 0,000 0,16918655 0,16989267 ! detection of stimulus GO:0051606 151 96 0,000 0,16918655 0,16982179 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,17079166 0,17136144 ! protein ubiquitination GO:0016567 217 97 0,000 0,17079166 0,17129001 ! hormone metabolic process GO:0042445 157 97 0,000 0,17079166 0,17121864 ! response to virus GO:0009615 160 98 0,000 0,17239373 0,17275273 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,17239373 0,17268081 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,17239373 0,17260895 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,17399276 0,17413751 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,17399276 0,1740651 ! cell cycle arrest GO:0007050 213 100 0,000 0,17558875 0,17558875