pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1183-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin receptor signaling pathway GO:0008286 40 24 2,000 5,691E-05 0,13089436 ! positive regulation of glycolysis GO:0045821 11 5 1,000 9,66E-05 0,11108648 ! regulation of respiratory burst GO:0060263 8 5 1,000 9,66E-05 0,07405765 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 1,446E-04 0,08314656 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! male sex determination GO:0030238 9 6 1,000 1,446E-04 0,06651724 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 1,646E-04 0,06307767 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 2,02E-04 0,0663829 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 2,02E-04 0,05808504 ! protein heterooligomerization GO:0051291 10 7 1,000 2,02E-04 0,05163115 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 2,688E-04 0,06183227 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 2,688E-04 0,05621115 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 2,688E-04 0,05152689 ! regulation of embryonic development GO:0045995 16 8 1,000 2,688E-04 0,04756328 ! response to insulin stimulus GO:0032868 63 43 2,000 3,326E-04 0,05464606 ! regulation of developmental growth GO:0048638 13 9 1,000 3,449E-04 0,05289209 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 3,449E-04 0,04958634 ! regulation of glycolysis GO:0006110 15 9 1,000 3,449E-04 0,04666949 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 4,303E-04 0,05498473 GO:0043470|regulation of carbohydrate catabolic process, ! integrin-mediated signaling pathway GO:0007229 81 49 2,000 4,9E-04 0,05931607 ! virus-host interaction GO:0019048 17 11 1,000 5,249E-04 0,06036115 ! positive regulation of cell migration GO:0030335 92 51 2,000 5,514E-04 0,06039168 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 6,286E-04 0,06571567 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 6,286E-04 0,06285847 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of cell motion GO:0051272 99 56 2,000 7,259E-04 0,06956145 ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 7,414E-04 0,06820644 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 7,645E-04 0,06762744 ! intermediate filament-based process GO:0045103 24 14 1,000 8,632E-04 0,07353121 ! axon cargo transport GO:0008088 27 14 1,000 8,632E-04 0,0709051 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,134E-03 0,08991341 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,134E-03 0,0869163 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 1,282E-03 0,09513543 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,44E-03 0,10347384 ! protein import into nucleus, docking GO:0000059 30 19 1,000 1,606E-03 0,11191686 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 1,606E-03 0,10862519 GO:0010675|regulation of cellular carbohydrate metabolic process, ! sex determination GO:0007530 29 19 1,000 1,606E-03 0,10552161 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 1,606E-03 0,10259046 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 1,631E-03 0,10138493 ! microtubule-based transport GO:0010970 37 20 1,000 1,781E-03 0,10777245 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 1,781E-03 0,10500906 ! mRNA transport GO:0051028 121 81 2,000 2,114E-03 0,12153276 ! protein tetramerization GO:0051262 39 22 1,000 2,156E-03 0,12095261 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,357E-03 0,12905753 ! interaction with host GO:0051701 37 23 1,000 2,357E-03 0,12605619 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 2,566E-03 0,13412004 ! establishment of RNA localization GO:0051236 128 88 2,000 2,677E-03 0,13680678 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 2,783E-03 0,13916372 ! RNA localization GO:0006403 135 91 2,000 2,944E-03 0,14404976 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 3,009E-03 0,14418839 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 2,000 3,424E-03 0,16071625 ! mesoderm formation GO:0001707 46 28 1,000 3,486E-03 0,16034728 ! positive regulation of catabolic process GO:0009896 40 28 1,000 3,486E-03 0,15720321 ! formation of primary germ layer GO:0001704 48 29 1,000 3,736E-03 0,16526793 ! regulation of microtubule-based process GO:0032886 58 30 1,000 3,995E-03 0,17338262 ! mammary gland development GO:0030879 57 31 1,000 4,262E-03 0,18154231 ! mesoderm morphogenesis GO:0048332 49 31 1,000 4,262E-03 0,17824154 ! cell fate specification GO:0001708 37 31 1,000 4,262E-03 0,17505865 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 4,537E-03 0,18308474 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 4,82E-03 0,19115167 ! carbohydrate homeostasis GO:0033500 39 33 1,000 4,82E-03 0,18791181 GO:0042593|glucose homeostasis, ! Notch signaling pathway GO:0007219 56 35 1,000 5,41E-03 0,20739208 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 7,022E-03 0,2647465 ! positive regulation of DNA binding GO:0043388 57 41 1,000 7,367E-03 0,27328512 ! positive regulation of binding GO:0051099 59 43 1,000 8,08E-03 0,29498392 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 8,08E-03 0,29037479 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 8,823E-03 0,31219867 ! chloride transport GO:0006821 67 48 1,000 9,993E-03 0,34822737 ! gastrulation GO:0007369 73 48 1,000 9,993E-03 0,34302995 ! heart morphogenesis GO:0003007 65 48 1,000 9,993E-03 0,33798539 ! regulation of DNA replication GO:0006275 75 48 1,000 9,993E-03 0,33308705 ! nuclear export GO:0051168 69 48 1,000 9,993E-03 0,32832867 ! membrane fusion GO:0006944 80 50 1,000 0,01080851 0,35013495 ! positive regulation of growth GO:0045927 67 50 1,000 0,01080851 0,34527196 ! mesoderm development GO:0007498 76 55 1,000 0,01297208 0,40870938 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,01342564 0,41728354 ! viral reproductive process GO:0022415 87 58 1,000 0,01435325 0,44016639 ! activation of MAPK activity GO:0000187 84 59 1,000 0,0148272 0,44871803 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01563357 0,46697691 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01563357 0,46099003 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01563357 0,45515471 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01563357 0,44946528 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01563357 0,44391632 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01563357 0,43850271 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01563357 0,43321955 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01563357 0,42806217 ! sleep GO:0030431 11 5 0,000 0,01563357 0,42302614 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01563357 0,41810724 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01563357 0,41330141 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01563357 0,4086048 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01563357 0,40401373 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01563357 0,39952469 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01563357 0,39513431 ! tongue development GO:0043586 6 5 0,000 0,01563357 0,39083937 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01563357 0,3866368 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01563357 0,38252364 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01563357 0,37849708 ! cobalt ion transport GO:0006824 9 5 0,000 0,01563357 0,3745544 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01563357 0,37069301 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01563357 0,36691043 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01563357 0,36320427 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01563357 0,35957222 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01563357 0,3560121 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01563357 0,35252179 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01563357 0,34909925 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01563357 0,34574252 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01563357 0,34244974 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01563357 0,33921908 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01563357 0,33604881 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01563357 0,33293724 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01563357 0,32988277 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01563357 0,32688384 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01563357 0,32393894 ! malate metabolic process GO:0006108 7 5 0,000 0,01563357 0,32104663 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01563357 0,31820551 ! behavioral response to pain GO:0048266 7 5 0,000 0,01563357 0,31541423 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01563357 0,3126715 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01563357 0,30997605 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01563357 0,30732669 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01563357 0,30472222 ! mating behavior GO:0007617 6 5 0,000 0,01563357 0,30216153 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01563357 0,29964352 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01563357 0,29716713 ! rhythmic behavior GO:0007622 12 5 0,000 0,01563357 0,29473133 ! copulation GO:0007620 7 5 0,000 0,01563357 0,29233514 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01563357 0,2899776 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01563357 0,28765778 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01563357 0,28537478 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01563357 0,28312773 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01563357 0,2809158 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01563357 0,27873816 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01563357 0,27659402 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01563357 0,27448261 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01563357 0,2724032 ! response to protozoan GO:0001562 9 5 0,000 0,01563357 0,27035505 ! lymph vessel development GO:0001945 7 5 0,000 0,01563357 0,26833748 ! endochondral ossification GO:0001958 12 5 0,000 0,01563357 0,26634979 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01563357 0,26439134 ! parathyroid gland development GO:0060017 8 5 0,000 0,01563357 0,26246148 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01563357 0,26055958 ! anagen GO:0042640 6 5 0,000 0,01563357 0,25868505 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01563357 0,2568373 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01563357 0,25501576 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01563357 0,25321988 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01563357 0,25144911 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01563357 0,24970293 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01563357 0,24798084 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01563357 0,24628234 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01563357 0,24460695 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01563357 0,2429542 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01563357 0,24132364 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01563357 0,23971482 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01563357 0,2381273 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01563357 0,23656067 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01563357 0,23501452 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01563357 0,23348846 ! ovulation GO:0030728 6 5 0,000 0,01563357 0,23198208 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01563357 0,23049501 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01563357 0,22902689 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01563357 0,22757736 ! response to pH GO:0009268 9 5 0,000 0,01563357 0,22614605 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01563357 0,22473264 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01563357 0,22333678 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01563357 0,22195816 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01563357 0,22059646 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01563357 0,21925136 ! polyol catabolic process GO:0046174 7 5 0,000 0,01563357 0,21792256 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01563357 0,21660977 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01563357 0,21531271 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01563357 0,21403108 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01563357 0,21276463 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01563357 0,21151307 ! urea metabolic process GO:0019627 6 5 0,000 0,01563357 0,21027615 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01563357 0,20905362 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01563357 0,20784522 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01563357 0,2066507 ! neutrophil activation GO:0042119 5 5 0,000 0,01563357 0,20546984 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01563357 0,2043024 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01563357 0,20314815 ! response to food GO:0032094 5 5 0,000 0,01563357 0,20200687 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01563357 0,20087834 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01563357 0,19976235 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01563357 0,19865869 ! forebrain neuron development GO:0021884 7 5 0,000 0,01563357 0,19756716 ! melanosome organization GO:0032438 7 5 0,000 0,01563357 0,19648755 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01563357 0,19541969 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01563357 0,19436336 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01563357 0,1933184 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01563357 0,19228461 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01563357 0,19126182 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01563357 0,19024985 ! nucleoside transport GO:0015858 6 5 0,000 0,01563357 0,18924854 ! nucleoside salvage GO:0043174 7 5 0,000 0,01563357 0,18825771 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01563357 0,1872772 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01563357 0,18630685 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01563357 0,18534651 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01563357 0,18439601 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01563357 0,18345522 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01563357 0,18252397 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01563357 0,18160213 ! depyrimidination GO:0045008 8 5 0,000 0,01563357 0,18068956 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01563357 0,17978611 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01563357 0,17889165 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01563357 0,17800605 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01563357 0,17712917 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01563357 0,17626089 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01563357 0,17540108 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01563357 0,17454962 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01563357 0,17370639 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01563357 0,17287126 ! monocyte differentiation GO:0030224 8 5 0,000 0,01563357 0,17204413 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01563357 0,17122487 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01563357 0,17041338 ! centrosome duplication GO:0051298 5 5 0,000 0,01563357 0,16960954 ! response to UV-C GO:0010225 6 5 0,000 0,01563357 0,16881325 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01563357 0,1680244 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01563357 0,16724289 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01563357 0,16646862 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01563357 0,16570149 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01563357 0,16494139 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01563357 0,16418823 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01563357 0,16344192 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01563357 0,16270236 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01563357 0,16196947 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01563357 0,16124315 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01563357 0,16052331 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01563357 0,15980988 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01563357 0,15910275 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01563357 0,15840186 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01563357 0,15770712 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01563357 0,15701844 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01563357 0,15633575 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01563357 0,15565897 ! neural tube patterning GO:0021532 6 5 0,000 0,01563357 0,15498803 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01563357 0,15432284 ! histone demethylation GO:0016577 9 5 0,000 0,01563357 0,15366334 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01563357 0,15300946 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01563357 0,15236111 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01563357 0,15171824 ! enteric nervous system development GO:0048484 8 5 0,000 0,01563357 0,15108077 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01563357 0,15044863 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01563357 0,14982176 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01563357 0,14920009 ! transcription termination GO:0006353 8 5 0,000 0,01563357 0,14858356 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01563357 0,14797211 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01563357 0,14736566 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01563357 0,14676417 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01563357 0,14616757 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01563357 0,1455758 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01563357 0,1449888 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01563357 0,14440652 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01563357 0,14382889 ! apical protein localization GO:0045176 6 5 0,000 0,01563357 0,14325587 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01563357 0,14268739 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01563357 0,14212341 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01563357 0,14156387 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01563357 0,14100871 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01563357 0,1404579 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01563357 0,13991137 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01563357 0,13936908 ! glial cell migration GO:0008347 10 5 0,000 0,01563357 0,13883097 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01563357 0,13829701 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01563357 0,13776714 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01563357 0,13724131 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01563357 0,13671948 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01563357 0,1362016 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01563357 0,13568763 ! neural plate development GO:0001840 6 5 0,000 0,01563357 0,13517753 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01563357 0,13467124 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01563357 0,13416874 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01563357 0,13366997 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01563357 0,1331749 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01563357 0,13268348 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01563357 0,13219567 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01563357 0,13171144 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01563357 0,13123074 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01563357 0,13075354 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01563357 0,13027979 ! spindle assembly GO:0051225 5 5 0,000 0,01563357 0,12980947 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01563357 0,12934253 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01563357 0,12887893 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01563357 0,12841865 ! organ regeneration GO:0031100 7 5 0,000 0,01563357 0,12796165 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01563357 0,12750788 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01563357 0,12705732 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01563357 0,12660994 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01563357 0,12616569 GO:0055081|anion homeostasis, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,01579518 0,12702417 ! viral reproduction GO:0016032 92 63 1,000 0,01678961 0,1345509 ! protein oligomerization GO:0051259 100 65 1,000 0,01781015 0,14223381 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,01833009 0,14587962 ! tRNA transcription GO:0009304 11 6 0,000 0,01873137 0,14855914 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01873137 0,14804862 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01873137 0,14754161 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01873137 0,14703805 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01873137 0,14653792 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01873137 0,14604118 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01873137 0,1455478 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01873137 0,14505774 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01873137 0,14457097 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01873137 0,14408746 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01873137 0,14360716 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01873137 0,14313006 ! prostate gland development GO:0030850 9 6 0,000 0,01873137 0,14265612 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01873137 0,14218531 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01873137 0,1417176 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01873137 0,14125295 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01873137 0,14079134 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01873137 0,14033273 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01873137 0,13987711 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01873137 0,13942443 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01873137 0,13897468 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01873137 0,13852781 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01873137 0,13808381 ! neuron adhesion GO:0007158 9 6 0,000 0,01873137 0,13764265 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01873137 0,1372043 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01873137 0,13676873 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01873137 0,13633592 ! signal peptide processing GO:0006465 8 6 0,000 0,01873137 0,13590583 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01873137 0,13547846 ! mRNA stabilization GO:0048255 15 6 0,000 0,01873137 0,13505376 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01873137 0,13463172 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01873137 0,1342123 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01873137 0,1337955 ! opsonization GO:0008228 8 6 0,000 0,01873137 0,13338127 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01873137 0,1329696 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01873137 0,13256046 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01873137 0,13215383 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01873137 0,13174969 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01873137 0,13134802 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01873137 0,13094878 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01873137 0,13055197 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01873137 0,13015755 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01873137 0,12976551 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01873137 0,12937582 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01873137 0,12898847 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01873137 0,12860343 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01873137 0,12822068 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01873137 0,12784021 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01873137 0,12746198 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01873137 0,12708599 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01873137 0,1267122 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01873137 0,12634061 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01873137 0,1259712 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01873137 0,12560393 ! thymic T cell selection GO:0045061 12 6 0,000 0,01873137 0,12523881 ! protein lipoylation GO:0009249 10 6 0,000 0,01873137 0,1248758 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01873137 0,12451488 ! pigment granule organization GO:0048753 11 6 0,000 0,01873137 0,12415605 ! drug transport GO:0015893 6 6 0,000 0,01873137 0,12379928 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01873137 0,12344455 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01873137 0,12309186 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01873137 0,12274117 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01873137 0,12239247 ! histidine metabolic process GO:0006547 6 6 0,000 0,01873137 0,12204575 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01873137 0,12170099 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01873137 0,12135817 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,01873137 0,12101727 ! adenohypophysis development GO:0021984 10 6 0,000 0,01873137 0,12067829 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01873137 0,1203412 ! hyperosmotic response GO:0006972 8 6 0,000 0,01873137 0,12000599 ! microtubule nucleation GO:0007020 10 6 0,000 0,01873137 0,11967264 ! ER overload response GO:0006983 7 6 0,000 0,01873137 0,11934113 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01873137 0,11901146 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01873137 0,11868361 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01873137 0,11835755 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01873137 0,11803329 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01873137 0,11771079 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01873137 0,11739005 ! response to dietary excess GO:0002021 7 6 0,000 0,01873137 0,11707106 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01873137 0,11675379 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01873137 0,11643824 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01873137 0,11612439 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01873137 0,11581223 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01873137 0,11550174 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01873137 0,11519291 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01873137 0,11488573 ! neuron apoptosis GO:0051402 8 6 0,000 0,01873137 0,11458018 ! organic alcohol transport GO:0015850 9 6 0,000 0,01873137 0,11427626 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01873137 0,11397394 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01873137 0,11367322 ! carnitine transport GO:0015879 8 6 0,000 0,01873137 0,11337408 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01873137 0,11307651 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01873137 0,1127805 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01873137 0,11248603 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01873137 0,1121931 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01873137 0,11190169 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01873137 0,11161179 ! parturition GO:0007567 12 6 0,000 0,01873137 0,11132338 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01873137 0,11103647 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01873137 0,11075103 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01873137 0,11046705 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01873137 0,11018453 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01873137 0,10990344 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01873137 0,10962379 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01873137 0,10934556 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01873137 0,10906873 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01873137 0,10879331 ! macrophage differentiation GO:0030225 10 6 0,000 0,01873137 0,10851927 ! astrocyte development GO:0014002 14 6 0,000 0,01873137 0,10824661 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01873137 0,10797531 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01873137 0,10770537 ! interaction with symbiont GO:0051702 8 6 0,000 0,01873137 0,10743678 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01873137 0,10716953 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01873137 0,1069036 ! eating behavior GO:0042755 6 6 0,000 0,01873137 0,10663898 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01873137 0,10637568 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01873137 0,10611367 ! response to copper ion GO:0046688 9 6 0,000 0,01873137 0,10585295 ! DNA topological change GO:0006265 8 6 0,000 0,01873137 0,1055935 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01873137 0,10533533 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01873137 0,10507841 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01873137 0,10482275 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01873137 0,10456832 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01873137 0,10431513 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01873137 0,10406316 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01873137 0,10381241 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01873137 0,10356286 ! gas homeostasis GO:0033483 11 6 0,000 0,01873137 0,10331451 ! hair follicle maturation GO:0048820 7 6 0,000 0,01873137 0,10306734 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01873137 0,10282136 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01873137 0,10257655 ! Schwann cell development GO:0014044 14 6 0,000 0,01873137 0,1023329 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01873137 0,1020904 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01873137 0,10184905 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01873137 0,10160884 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01873137 0,10136976 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01873137 0,10113181 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01873137 0,10089496 ! histone ubiquitination GO:0016574 7 6 0,000 0,01873137 0,10065923 ! regulation of meiosis GO:0040020 10 6 0,000 0,01873137 0,10042459 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01873137 0,10019105 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01873137 0,09995858 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01873137 0,0997272 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01873137 0,09949688 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01873137 0,09926763 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01873137 0,09903942 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01873137 0,09881227 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01873137 0,09858615 ! receptor internalization GO:0031623 9 6 0,000 0,01873137 0,09836107 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01873137 0,09813701 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01873137 0,09791398 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01873137 0,09769195 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01873137 0,09747093 ! protein deubiquitination GO:0016579 8 6 0,000 0,01873137 0,0972509 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01873137 0,09703187 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01873137 0,09681382 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01873137 0,09659675 ! axonal fasciculation GO:0007413 9 6 0,000 0,01873137 0,09638065 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01873137 0,09616551 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01873137 0,09595134 ! midbrain development GO:0030901 6 6 0,000 0,01873137 0,09573811 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01873137 0,09552583 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01873137 0,09531449 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01873137 0,09510408 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01873137 0,0948946 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01873137 0,09468604 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01873137 0,0944784 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01873137 0,09427166 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01873137 0,09406583 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01873137 0,09386089 ! adult feeding behavior GO:0008343 6 6 0,000 0,01873137 0,09365685 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01873137 0,09345369 ! blastocyst growth GO:0001832 15 6 0,000 0,01873137 0,09325141 ! pigment granule transport GO:0051904 12 6 0,000 0,01873137 0,09305 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01873137 0,09284946 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01873137 0,09264978 ! catecholamine transport GO:0051937 7 6 0,000 0,01873137 0,09245096 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01873137 0,092253 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01873137 0,09205587 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01873137 0,09185959 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01873137 0,09166415 ! protein prenylation GO:0018342 10 6 0,000 0,01873137 0,09146953 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01873137 0,09127574 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01873137 0,09108277 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01873137 0,09089061 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01873137 0,09069926 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01873137 0,09050872 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,01938911 0,09349048 ! inorganic anion transport GO:0015698 93 68 1,000 0,01938911 0,0932949 ! regulation of catabolic process GO:0009894 106 70 1,000 0,02047336 0,0983063 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,02181959 0,10455221 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02181959 0,10433485 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02181959 0,10411838 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02181959 0,10390282 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02181959 0,10368814 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02181959 0,10347435 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02181959 0,10326144 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02181959 0,10304941 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02181959 0,10283824 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02181959 0,10262794 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02181959 0,10241849 ! reproductive behavior GO:0019098 12 7 0,000 0,02181959 0,1022099 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02181959 0,10200216 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02181959 0,10179526 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02181959 0,10158919 ! oligopeptide transport GO:0006857 11 7 0,000 0,02181959 0,10138396 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02181959 0,10117956 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02181959 0,10097598 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02181959 0,10077321 ! RNA methylation GO:0001510 11 7 0,000 0,02181959 0,10057126 ! pericardium development GO:0060039 8 7 0,000 0,02181959 0,10037012 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02181959 0,10016978 ! fibril organization GO:0043206 13 7 0,000 0,02181959 0,09997024 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02181959 0,09977149 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02181959 0,09957353 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02181959 0,09937636 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02181959 0,09917996 ! lipoprotein transport GO:0042953 9 7 0,000 0,02181959 0,09898434 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02181959 0,09878949 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02181959 0,0985954 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02181959 0,09840208 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02181959 0,09820951 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02181959 0,0980177 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02181959 0,09782663 ! chemosensory behavior GO:0007635 9 7 0,000 0,02181959 0,09763631 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02181959 0,09744672 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,02181959 0,09725787 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02181959 0,09706975 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02181959 0,09688236 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02181959 0,09669569 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02181959 0,09650973 ! reflex GO:0060004 12 7 0,000 0,02181959 0,09632449 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02181959 0,09613996 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02181959 0,09595614 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02181959 0,09577302 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02181959 0,09559059 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02181959 0,09540886 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02181959 0,09522782 ! spinal cord patterning GO:0021511 7 7 0,000 0,02181959 0,09504746 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02181959 0,09486779 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02181959 0,09468879 ! adrenal gland development GO:0030325 17 7 0,000 0,02181959 0,09451047 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02181959 0,09433282 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02181959 0,09415584 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02181959 0,09397951 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02181959 0,09380385 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02181959 0,09362885 ! endosome organization GO:0007032 10 7 0,000 0,02181959 0,09345449 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02181959 0,09328078 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02181959 0,09310772 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02181959 0,0929353 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02181959 0,09276351 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02181959 0,09259236 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02181959 0,09242184 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02181959 0,09225195 ! galactose metabolic process GO:0006012 10 7 0,000 0,02181959 0,09208268 ! vesicle fusion GO:0006906 15 7 0,000 0,02181959 0,09191403 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02181959 0,091746 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02181959 0,09157858 ! organ growth GO:0035265 11 7 0,000 0,02181959 0,09141177 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02181959 0,09124557 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02181959 0,09107997 ! retinol metabolic process GO:0042572 9 7 0,000 0,02181959 0,09091497 ! behavioral fear response GO:0001662 13 7 0,000 0,02181959 0,09075056 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02181959 0,09058675 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02181959 0,09042353 ! rRNA modification GO:0000154 12 7 0,000 0,02181959 0,0902609 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02181959 0,09009885 ! response to UV-B GO:0010224 11 7 0,000 0,02181959 0,08993739 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,02181959 0,0897765 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02181959 0,08961618 ! intermediate filament organization GO:0045109 11 7 0,000 0,02181959 0,08945644 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02181959 0,08929726 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02181959 0,08913865 ! fibrinolysis GO:0042730 9 7 0,000 0,02181959 0,0889806 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02181959 0,08882312 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02181959 0,08866619 ! B cell lineage commitment GO:0002326 17 7 0,000 0,02181959 0,08850981 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02181959 0,08835398 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02181959 0,0881987 ! response to tropane GO:0014073 13 7 0,000 0,02181959 0,08804397 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02181959 0,08788977 ! melanosome localization GO:0032400 10 7 0,000 0,02181959 0,08773612 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02181959 0,087583 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02181959 0,08743042 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02181959 0,08727837 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02181959 0,08712684 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02181959 0,08697584 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02181959 0,08682537 ! mast cell activation GO:0045576 9 7 0,000 0,02181959 0,08667541 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02181959 0,08652597 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02181959 0,08637704 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02181959 0,08622863 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02181959 0,08608072 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02181959 0,08593332 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02181959 0,08578643 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02181959 0,08564004 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02181959 0,08549414 ! T cell lineage commitment GO:0002360 12 7 0,000 0,02181959 0,08534874 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02181959 0,08520384 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02181959 0,08505943 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02181959 0,0849155 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02181959 0,08477206 ! response to tumor cell GO:0002347 12 7 0,000 0,02181959 0,08462911 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02181959 0,08448663 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02181959 0,08434464 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02181959 0,08420312 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02181959 0,08406208 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02181959 0,08392151 ! diuresis GO:0030146 12 7 0,000 0,02181959 0,0837814 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02181959 0,08364177 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02181959 0,0835026 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02181959 0,08336389 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02181959 0,08322564 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02181959 0,08308785 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02181959 0,08295051 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02181959 0,08281363 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02181959 0,0826772 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02181959 0,08254122 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02181959 0,08240568 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02181959 0,08227059 ! lymph node development GO:0048535 9 7 0,000 0,02181959 0,08213594 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02181959 0,08200173 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02181959 0,08186796 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02181959 0,08173463 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02181959 0,08160173 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02181959 0,08146925 ! ATP catabolic process GO:0006200 10 7 0,000 0,02181959 0,08133721 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02181959 0,0812056 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02181959 0,08107441 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02181959 0,08094365 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02181959 0,0808133 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02181959 0,08068338 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02181959 0,08055387 ! muscle adaptation GO:0043500 12 7 0,000 0,02181959 0,08042478 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02181959 0,0802961 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02181959 0,08016783 ! retina homeostasis GO:0001895 9 7 0,000 0,02181959 0,08003997 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02181959 0,07991252 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02181959 0,07978547 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02181959 0,07965883 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02181959 0,07953258 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02181959 0,07940674 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02181959 0,0792813 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02181959 0,07915625 ! protein import into nucleus GO:0006606 118 74 1,000 0,02271612 0,08227886 ! nuclear import GO:0051170 121 75 1,000 0,02329204 0,08423221 ! regulation of DNA binding GO:0051101 119 77 1,000 0,02446184 0,08832377 ! gland development GO:0048732 148 77 1,000 0,02446184 0,08818533 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02489827 0,08961819 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02489827 0,08947816 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02489827 0,08933857 ! axon extension GO:0048675 11 8 0,000 0,02489827 0,08919941 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02489827 0,08906069 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02489827 0,0889224 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02489827 0,08878453 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02489827 0,0886471 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02489827 0,08851008 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02489827 0,08837349 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02489827 0,08823732 ! phosphate transport GO:0006817 10 8 0,000 0,02489827 0,08810157 ! N-glycan processing GO:0006491 12 8 0,000 0,02489827 0,08796624 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02489827 0,08783132 ! UTP metabolic process GO:0046051 8 8 0,000 0,02489827 0,08769682 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02489827 0,08756273 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02489827 0,08742904 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02489827 0,08729577 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02489827 0,0871629 ! succinate metabolic process GO:0006105 14 8 0,000 0,02489827 0,08703043 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02489827 0,08689837 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02489827 0,0867667 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02489827 0,08663544 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02489827 0,08650457 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02489827 0,08637409 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02489827 0,08624401 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02489827 0,08611432 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02489827 0,08598502 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02489827 0,08585611 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02489827 0,08572758 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02489827 0,08559944 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02489827 0,08547168 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02489827 0,0853443 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02489827 0,0852173 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02489827 0,08509067 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02489827 0,08496443 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02489827 0,08483855 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02489827 0,08471305 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02489827 0,08458792 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02489827 0,08446316 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02489827 0,08433877 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02489827 0,08421474 ! melanin metabolic process GO:0006582 12 8 0,000 0,02489827 0,08409108 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02489827 0,08396778 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02489827 0,08384484 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02489827 0,08372226 ! macrophage activation GO:0042116 12 8 0,000 0,02489827 0,08360003 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02489827 0,08347817 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02489827 0,08335666 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02489827 0,0832355 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02489827 0,08311469 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02489827 0,08299424 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02489827 0,08287413 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02489827 0,08275437 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02489827 0,08263495 ! ruffle organization GO:0031529 11 8 0,000 0,02489827 0,08251588 ! osteoblast development GO:0002076 13 8 0,000 0,02489827 0,08239716 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02489827 0,08227877 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02489827 0,08216072 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02489827 0,08204301 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02489827 0,08192564 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02489827 0,08180861 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02489827 0,0816919 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02489827 0,08157553 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02489827 0,08145949 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02489827 0,08134378 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02489827 0,0812284 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02489827 0,08111335 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02489827 0,08099862 ! segment specification GO:0007379 10 8 0,000 0,02489827 0,08088421 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02489827 0,08077013 ! cellular extravasation GO:0045123 11 8 0,000 0,02489827 0,08065637 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02489827 0,08054293 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02489827 0,08042981 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02489827 0,080317 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02489827 0,08020451 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02489827 0,08009234 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02489827 0,07998048 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02489827 0,07986893 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02489827 0,07975769 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02489827 0,07964676 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02489827 0,07953614 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02489827 0,07942583 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02489827 0,07931582 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02489827 0,07920612 ! icosanoid secretion GO:0032309 12 8 0,000 0,02489827 0,07909672 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02489827 0,07898762 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02489827 0,07887882 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02489827 0,07877032 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02489827 0,07866212 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02489827 0,07855422 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02489827 0,07844661 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02489827 0,07833929 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02489827 0,07823227 ! sterol catabolic process GO:0016127 9 8 0,000 0,02489827 0,07812554 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02489827 0,07801911 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02489827 0,07791296 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02489827 0,0778071 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02489827 0,07770152 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02489827 0,07759624 ! prophase GO:0051324 11 8 0,000 0,02489827 0,07749124 ! S phase GO:0051320 8 8 0,000 0,02489827 0,07738652 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02489827 0,07728208 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02489827 0,07717793 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02489827 0,07707406 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02489827 0,07697046 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02489827 0,07686715 ! hormone catabolic process GO:0042447 13 8 0,000 0,02489827 0,07676411 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02489827 0,07666134 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02489827 0,07655886 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02489827 0,07645664 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02489827 0,0763547 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02489827 0,07625303 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02489827 0,07615163 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02489827 0,0760505 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02489827 0,07594963 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02489827 0,07584904 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02489827 0,07574871 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02489827 0,07564864 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02489827 0,07554884 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02489827 0,07544931 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02489827 0,07535003 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02489827 0,07525102 ! ATP biosynthetic process GO:0006754 118 79 1,000 0,02565534 0,07743737 ! protein localization in nucleus GO:0034504 133 80 1,000 0,02626086 0,07916119 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02796744 0,08419516 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02796744 0,0840851 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02796744 0,08397533 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02796744 0,08386585 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02796744 0,08375665 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02796744 0,08364773 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02796744 0,0835391 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02796744 0,08343074 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02796744 0,08332267 ! GTP metabolic process GO:0046039 9 9 0,000 0,02796744 0,08321488 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02796744 0,08310737 ! social behavior GO:0035176 14 9 0,000 0,02796744 0,08300013 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02796744 0,08289318 ! artery development GO:0060840 19 9 0,000 0,02796744 0,08278649 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02796744 0,08268008 ! response to pain GO:0048265 16 9 0,000 0,02796744 0,08257395 ! protein complex disassembly GO:0043241 17 9 0,000 0,02796744 0,08246808 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02796744 0,08236249 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02796744 0,08225717 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02796744 0,08215211 ! lung alveolus development GO:0048286 17 9 0,000 0,02796744 0,08204733 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02796744 0,08194281 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02796744 0,08183855 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02796744 0,08173457 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02796744 0,08163084 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02796744 0,08152738 ! protein targeting to ER GO:0045047 19 9 0,000 0,02796744 0,08142418 ! T cell selection GO:0045058 18 9 0,000 0,02796744 0,08132124 ! endoderm development GO:0007492 12 9 0,000 0,02796744 0,08121857 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02796744 0,08111615 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02796744 0,08101398 ! arginine catabolic process GO:0006527 10 9 0,000 0,02796744 0,08091208 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02796744 0,08081043 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02796744 0,08070904 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02796744 0,0806079 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02796744 0,08050701 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02796744 0,08040638 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02796744 0,080306 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02796744 0,08020587 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02796744 0,08010598 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02796744 0,08000635 ! mannose metabolic process GO:0006013 9 9 0,000 0,02796744 0,07990696 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02796744 0,07980782 ! receptor clustering GO:0043113 15 9 0,000 0,02796744 0,07970893 ! epithelial cell development GO:0002064 10 9 0,000 0,02796744 0,07961028 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02796744 0,07951187 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02796744 0,07941371 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02796744 0,07931579 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02796744 0,07921811 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02796744 0,07912067 ! motor axon guidance GO:0008045 14 9 0,000 0,02796744 0,07902347 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02796744 0,07892651 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02796744 0,07882978 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02796744 0,0787333 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02796744 0,07863705 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02796744 0,07854103 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02796744 0,07844525 ! DNA ligation GO:0006266 14 9 0,000 0,02796744 0,0783497 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02796744 0,07825438 ! response to amine stimulus GO:0014075 13 9 0,000 0,02796744 0,0781593 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02796744 0,07806445 ! erythrocyte development GO:0048821 11 9 0,000 0,02796744 0,07796982 ! renal water homeostasis GO:0003091 14 9 0,000 0,02796744 0,07787543 ! postreplication repair GO:0006301 11 9 0,000 0,02796744 0,07778126 ! mRNA cleavage GO:0006379 13 9 0,000 0,02796744 0,07768732 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02796744 0,07759361 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02796744 0,07750013 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02796744 0,07740686 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02796744 0,07731383 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02796744 0,07722101 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02796744 0,07712842 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02796744 0,07703605 ! acid secretion GO:0046717 14 9 0,000 0,02796744 0,0769439 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02796744 0,07685198 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02796744 0,07676027 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02796744 0,07666878 ! purine base metabolic process GO:0006144 18 9 0,000 0,02796744 0,0765775 ! oocyte differentiation GO:0009994 12 9 0,000 0,02796744 0,07648645 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02796744 0,07639561 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02796744 0,07630499 ! spleen development GO:0048536 15 9 0,000 0,02796744 0,07621458 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02796744 0,07612438 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02796744 0,0760344 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02796744 0,07594463 ! detection of calcium ion GO:0005513 13 9 0,000 0,02796744 0,07585508 ! blastocyst formation GO:0001825 12 9 0,000 0,02796744 0,07576573 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02796744 0,07567659 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02796744 0,07558767 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02796744 0,07549895 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02796744 0,07541044 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02796744 0,07532214 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02796744 0,07523404 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02796744 0,07514615 ! prepulse inhibition GO:0060134 14 9 0,000 0,02796744 0,07505846 ! embryonic placenta development GO:0001892 12 9 0,000 0,02796744 0,07497098 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02796744 0,07488371 ! insulin secretion GO:0030073 17 9 0,000 0,02796744 0,07479663 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02796744 0,07470976 ! response to nicotine GO:0035094 16 9 0,000 0,02796744 0,07462309 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02796744 0,07453662 ! nucleus localization GO:0051647 15 9 0,000 0,02796744 0,07445035 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02796744 0,07436428 ! localization within membrane GO:0051668 15 9 0,000 0,02796744 0,07427841 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,02874053 0,07624362 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,02937463 0,07783601 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,02937463 0,07774644 ! cell cycle arrest GO:0007050 150 86 1,000 0,03001433 0,07934823 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 1,000 0,03065958 0,08096101 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03102712 0,08183758 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03102712 0,08174384 ! neuron fate specification GO:0048665 11 10 0,000 0,03102712 0,08165031 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03102712 0,08155699 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03102712 0,08146389 ! thyroid gland development GO:0030878 19 10 0,000 0,03102712 0,081371 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03102712 0,08127832 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03102712 0,08118586 ! synapsis GO:0007129 13 10 0,000 0,03102712 0,0810936 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03102712 0,08100155 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03102712 0,08090971 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03102712 0,08081808 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03102712 0,08072666 ! sulfate transport GO:0008272 12 10 0,000 0,03102712 0,08063544 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03102712 0,08054443 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03102712 0,08045363 ! androgen metabolic process GO:0008209 13 10 0,000 0,03102712 0,08036303 ! phospholipid efflux GO:0033700 16 10 0,000 0,03102712 0,08027263 ! hippocampus development GO:0021766 19 10 0,000 0,03102712 0,08018244 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,03102712 0,08009244 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03102712 0,08000265 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03102712 0,07991307 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03102712 0,07982368 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03102712 0,07973449 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03102712 0,0796455 ! pathogenesis GO:0009405 13 10 0,000 0,03102712 0,07955671 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03102712 0,07946812 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03102712 0,07937972 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03102712 0,07929152 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,03102712 0,07920352 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03102712 0,07911571 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03102712 0,07902809 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03102712 0,07894067 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03102712 0,07885345 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03102712 0,07876641 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03102712 0,07867957 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03102712 0,07859292 ! response to X-ray GO:0010165 16 10 0,000 0,03102712 0,07850646 ! B cell proliferation GO:0042100 14 10 0,000 0,03102712 0,07842018 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03102712 0,0783341 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03102712 0,07824821 ! forebrain cell migration GO:0021885 17 10 0,000 0,03102712 0,07816251 ! lipid digestion GO:0044241 15 10 0,000 0,03102712 0,07807699 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03102712 0,07799166 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03102712 0,07790652 ! UV protection GO:0009650 14 10 0,000 0,03102712 0,07782156 ! entry into host cell GO:0030260 20 10 0,000 0,03102712 0,07773678 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03102712 0,0776522 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03102712 0,07756779 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03102712 0,07748357 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03102712 0,07739953 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03102712 0,07731568 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03102712 0,077232 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03102712 0,07714851 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03102712 0,07706519 ! regulation of organ growth GO:0046620 11 10 0,000 0,03102712 0,07698206 ! response to dsRNA GO:0043331 18 10 0,000 0,03102712 0,0768991 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03102712 0,07681633 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03102712 0,07673373 ! embryonic axis specification GO:0000578 12 10 0,000 0,03102712 0,07665131 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03102712 0,07656906 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03102712 0,076487 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03102712 0,07640511 ! cranial nerve development GO:0021545 12 10 0,000 0,03102712 0,07632339 ! fucose catabolic process GO:0019317 16 10 0,000 0,03102712 0,07624185 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03102712 0,07616048 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03102712 0,07607928 ! protein sumoylation GO:0016925 12 10 0,000 0,03102712 0,07599826 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03102712 0,07591741 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03102712 0,07583674 ! zymogen activation GO:0031638 14 10 0,000 0,03102712 0,07575623 ! salivary gland development GO:0007431 22 10 0,000 0,03102712 0,07567589 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03102712 0,07559573 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03102712 0,07551573 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03102712 0,07543591 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03102712 0,07535625 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03102712 0,07527676 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03102712 0,07519744 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03102712 0,07511828 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03102712 0,07503929 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03102712 0,07496047 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03102712 0,07488181 ! detection of bacterium GO:0016045 10 10 0,000 0,03102712 0,07480332 ! embryonic gut development GO:0048566 11 10 0,000 0,03102712 0,07472499 ! activation of innate immune response GO:0002218 10 10 0,000 0,03102712 0,07464683 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03102712 0,07456883 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03102712 0,07449099 ! developmental induction GO:0031128 13 10 0,000 0,03102712 0,07441331 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03102712 0,0743358 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03102712 0,07425845 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03102712 0,07418126 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03102712 0,07410422 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 1,000 0,03131035 0,07470311 ! reproductive developmental process GO:0003006 127 89 1,000 0,03196659 0,07618979 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 1,000 0,03196659 0,07611092 ! ATP metabolic process GO:0046034 137 91 1,000 0,03329533 0,07919262 ! response to virus GO:0009615 122 91 1,000 0,03329533 0,07911081 ! cell fate commitment GO:0045165 141 92 1,000 0,03396776 0,08062523 ! rRNA transcription GO:0009303 17 11 0,000 0,03407734 0,08080194 ! respiratory burst GO:0045730 14 11 0,000 0,03407734 0,08071873 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03407734 0,08063568 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03407734 0,08055281 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03407734 0,08047011 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,03407734 0,08038757 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03407734 0,08030521 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03407734 0,08022301 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03407734 0,08014098 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03407734 0,08005912 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03407734 0,07997743 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03407734 0,0798959 ! mating GO:0007618 14 11 0,000 0,03407734 0,07981454 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03407734 0,07973335 ! T cell proliferation GO:0042098 20 11 0,000 0,03407734 0,07965232 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03407734 0,07957145 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03407734 0,07949075 ! bone resorption GO:0045453 16 11 0,000 0,03407734 0,07941022 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03407734 0,07932984 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03407734 0,07924963 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03407734 0,07916958 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03407734 0,07908969 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03407734 0,07900996 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03407734 0,0789304 ! syncytium formation GO:0006949 15 11 0,000 0,03407734 0,07885099 ! plasma membrane organization GO:0007009 18 11 0,000 0,03407734 0,07877174 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03407734 0,07869265 ! focal adhesion formation GO:0048041 24 11 0,000 0,03407734 0,07861372 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03407734 0,07853495 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03407734 0,07845634 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03407734 0,07837788 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03407734 0,07829958 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03407734 0,07822144 ! adult heart development GO:0007512 11 11 0,000 0,03407734 0,07814345 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03407734 0,07806562 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,03407734 0,07798794 ! temperature homeostasis GO:0001659 16 11 0,000 0,03407734 0,07791042 ! L-glutamate transport GO:0015813 16 11 0,000 0,03407734 0,07783305 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03407734 0,07775584 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03407734 0,07767877 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03407734 0,07760186 ! stem cell development GO:0048864 29 11 0,000 0,03407734 0,07752511 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03407734 0,0774485 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03407734 0,07737205 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03407734 0,07729574 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03407734 0,07721959 ! vasoconstriction GO:0042310 15 11 0,000 0,03407734 0,07714359 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03407734 0,07706773 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03407734 0,07699203 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03407734 0,07691647 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03407734 0,07684106 ! ribosome assembly GO:0042255 13 11 0,000 0,03407734 0,0767658 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03407734 0,07669069 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03407734 0,07661572 ! chromatin silencing GO:0006342 19 11 0,000 0,03407734 0,0765409 ! nucleosome positioning GO:0016584 13 11 0,000 0,03407734 0,07646623 ! T cell homeostasis GO:0043029 20 11 0,000 0,03407734 0,0763917 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03407734 0,07631732 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03407734 0,07624308 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03407734 0,07616898 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03407734 0,07609503 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03407734 0,07602122 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03407734 0,07594756 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03407734 0,07587404 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03407734 0,07580066 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03407734 0,07572742 ! male genitalia development GO:0030539 13 11 0,000 0,03407734 0,07565433 ! cholesterol efflux GO:0033344 19 11 0,000 0,03407734 0,07558137 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03407734 0,07550856 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03407734 0,07543588 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03407734 0,07536335 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03407734 0,07529095 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03407734 0,0752187 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03407734 0,07514658 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,03407734 0,0750746 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,03407734 0,07500276 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03407734 0,07493105 ! lysogeny GO:0030069 18 11 0,000 0,03407734 0,07485949 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03407734 0,07478806 ! acrosome reaction GO:0007340 13 11 0,000 0,03407734 0,07471676 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03407734 0,0746456 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,0346455 0,07581794 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,0346455 0,07574587 ! regulation of binding GO:0051098 151 95 1,000 0,03601679 0,07866915 ! lactation GO:0007595 20 12 0,000 0,03711814 0,08099783 ! reproductive cellular process GO:0048610 14 12 0,000 0,03711814 0,08092106 ! tRNA modification GO:0006400 14 12 0,000 0,03711814 0,08084443 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03711814 0,08076794 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03711814 0,0806916 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03711814 0,0806154 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03711814 0,08053935 ! non-recombinational repair GO:0000726 19 12 0,000 0,03711814 0,08046344 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03711814 0,08038768 ! peroxisomal transport GO:0043574 21 12 0,000 0,03711814 0,08031205 ! cartilage condensation GO:0001502 18 12 0,000 0,03711814 0,08023657 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03711814 0,08016123 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03711814 0,08008604 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03711814 0,08001098 ! heart looping GO:0001947 15 12 0,000 0,03711814 0,07993606 ! palate development GO:0060021 15 12 0,000 0,03711814 0,07986128 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03711814 0,07978665 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03711814 0,07971215 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03711814 0,07963779 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03711814 0,07956357 ! arginine metabolic process GO:0006525 13 12 0,000 0,03711814 0,07948949 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,03711814 0,07941555 ! methionine metabolic process GO:0006555 13 12 0,000 0,03711814 0,07934174 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03711814 0,07926807 ! Golgi organization GO:0007030 18 12 0,000 0,03711814 0,07919454 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03711814 0,07912114 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03711814 0,07904788 ! monoamine transport GO:0015844 13 12 0,000 0,03711814 0,07897476 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03711814 0,07890177 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03711814 0,07882891 ! L-amino acid transport GO:0015807 20 12 0,000 0,03711814 0,07875619 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03711814 0,07868361 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03711814 0,07861115 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03711814 0,07853883 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03711814 0,07846665 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03711814 0,07839459 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03711814 0,07832267 ! cerebellum development GO:0021549 13 12 0,000 0,03711814 0,07825088 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03711814 0,07817922 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03711814 0,0781077 ! histone acetylation GO:0016573 23 12 0,000 0,03711814 0,0780363 ! histone methylation GO:0016571 15 12 0,000 0,03711814 0,07796504 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03711814 0,0778939 ! gland morphogenesis GO:0022612 23 12 0,000 0,03711814 0,07782289 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03711814 0,07775202 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,03711814 0,07768127 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03711814 0,07761065 ! response to gamma radiation GO:0010332 20 12 0,000 0,03711814 0,07754016 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03711814 0,07746979 ! intestinal absorption GO:0050892 19 12 0,000 0,03711814 0,07739956 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03711814 0,07732945 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03711814 0,07725947 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03711814 0,07718961 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03711814 0,07711989 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,03711814 0,07705028 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03711814 0,07698081 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03711814 0,07691145 ! microspike assembly GO:0030035 23 12 0,000 0,03711814 0,07684223 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03711814 0,07677312 ! response to cold GO:0009409 14 12 0,000 0,03711814 0,07670415 ! calcium ion transport GO:0006816 167 99 1,000 0,03882148 0,08015206 ! protein import GO:0017038 156 99 1,000 0,03882148 0,08008018 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 1,000 0,03953537 0,0814797 ! divalent metal ion transport GO:0070838 171 100 1,000 0,03953537 0,08140675 ! protein localization in organelle GO:0033365 161 100 1,000 0,03953537 0,08133394 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,04014953 0,08252362 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04014953 0,08244993 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04014953 0,08237638 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04014953 0,08230296 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04014953 0,08222968 ! water transport GO:0006833 17 13 0,000 0,04014953 0,08215652 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04014953 0,08208349 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04014953 0,08201059 ! lipid localization GO:0010876 24 13 0,000 0,04014953 0,08193782 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04014953 0,08186518 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04014953 0,08179267 ! organelle fusion GO:0048284 28 13 0,000 0,04014953 0,08172029 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04014953 0,08164803 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04014953 0,08157591 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04014953 0,08150391 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04014953 0,08143203 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04014953 0,08136029 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04014953 0,08128867 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04014953 0,08121717 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04014953 0,08114581 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04014953 0,08107456 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04014953 0,08100344 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04014953 0,08093245 ! NAD metabolic process GO:0019674 21 13 0,000 0,04014953 0,08086158 ! exocrine system development GO:0035272 27 13 0,000 0,04014953 0,08079084 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04014953 0,08072022 ! bone mineralization GO:0030282 15 13 0,000 0,04014953 0,08064972 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04014953 0,08057934 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04014953 0,08050909 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04014953 0,08043896 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04014953 0,08036895 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04014953 0,08029907 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,04014953 0,0802293 ! genitalia development GO:0048806 15 13 0,000 0,04014953 0,08015966 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04014953 0,08009014 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,04014953 0,08002073 ! cellular pigmentation GO:0033059 24 13 0,000 0,04014953 0,07995145 ! tissue regeneration GO:0042246 21 13 0,000 0,04014953 0,07988229 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04014953 0,07981325 ! cofactor transport GO:0051181 19 13 0,000 0,04014953 0,07974432 ! NADP metabolic process GO:0006739 18 13 0,000 0,04014953 0,07967552 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04014953 0,07960683 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04014953 0,07953827 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04014953 0,07946982 ! gas transport GO:0015669 18 13 0,000 0,04014953 0,07940148 ! regulation of RNA stability GO:0043487 28 13 0,000 0,04014953 0,07933327 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04014953 0,07926517 ! regulation of axon extension GO:0030516 23 13 0,000 0,04014953 0,07919719 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04014953 0,07912933 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04014953 0,07906158 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04014953 0,07899395 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04014953 0,07892643 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04014953 0,07885903 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04014953 0,07879175 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04317156 0,08465012 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,04317156 0,08457801 ! superoxide anion generation GO:0042554 18 14 0,000 0,04317156 0,08450603 ! neuron maturation GO:0042551 21 14 0,000 0,04317156 0,08443417 ! regulation of S phase GO:0033261 18 14 0,000 0,04317156 0,08436244 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04317156 0,08429082 ! myotube differentiation GO:0014902 21 14 0,000 0,04317156 0,08421933 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,04317156 0,08414795 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,04317156 0,0840767 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04317156 0,08400557 ! inositol metabolic process GO:0006020 20 14 0,000 0,04317156 0,08393456 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04317156 0,08386367 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04317156 0,0837929 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04317156 0,08372225 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04317156 0,08365172 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04317156 0,0835813 ! response to cAMP GO:0051591 19 14 0,000 0,04317156 0,08351101 ! limbic system development GO:0021761 25 14 0,000 0,04317156 0,08344083 ! startle response GO:0001964 21 14 0,000 0,04317156 0,08337077 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04317156 0,08330083 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04317156 0,083231 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04317156 0,0831613 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04317156 0,0830917 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04317156 0,08302223 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04317156 0,08295287 ! glycine metabolic process GO:0006544 22 14 0,000 0,04317156 0,08288363 ! pituitary gland development GO:0021983 23 14 0,000 0,04317156 0,0828145 ! cellular response to starvation GO:0009267 21 14 0,000 0,04317156 0,08274549 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04317156 0,08267659 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04317156 0,08260781 ! regulation of heart rate GO:0002027 23 14 0,000 0,04317156 0,08253914 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04317156 0,08247059 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04317156 0,08240215 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04317156 0,08233382 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04317156 0,08226561 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,04317156 0,08219751 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,04317156 0,08212952 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04317156 0,08206164 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04317156 0,08199388 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04317156 0,08192623 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04317156 0,08185869 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04317156 0,08179126 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04317156 0,08172394 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04317156 0,08165673 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04317156 0,08158964 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04317156 0,08152265 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04317156 0,08145577 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04317156 0,08138901 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04317156 0,08132235 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04317156 0,0812558 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04317156 0,08118936 ! muscle maintenance GO:0046716 19 14 0,000 0,04317156 0,08112303 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04317156 0,08105681 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04317156 0,08099069 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04317156 0,08092468 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04317156 0,08085878 ! cell killing GO:0001906 20 14 0,000 0,04317156 0,08079299 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,04317156 0,08072731 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,04317156 0,08066173 ! cilium assembly GO:0042384 20 14 0,000 0,04317156 0,08059626 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04317156 0,08053089 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,04618424 0,08608084 ! positive regulation of cell size GO:0045793 20 15 0,000 0,04618424 0,08601114 ! metencephalon development GO:0022037 19 15 0,000 0,04618424 0,08594155 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,04618424 0,08587208 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,04618424 0,08580271 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,04618424 0,08573346 ! skin development GO:0043588 25 15 0,000 0,04618424 0,08566432 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,04618424 0,08559529 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,04618424 0,08552638 ! lipid phosphorylation GO:0046834 23 15 0,000 0,04618424 0,08545757 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,04618424 0,08538887 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,04618424 0,08532029 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,04618424 0,08525181 ! bile acid metabolic process GO:0008206 22 15 0,000 0,04618424 0,08518345 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,04618424 0,08511519 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,04618424 0,08504705 ! adult walking behavior GO:0007628 25 15 0,000 0,04618424 0,08497901 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,04618424 0,08491108 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,04618424 0,08484326 ! myoblast differentiation GO:0045445 27 15 0,000 0,04618424 0,08477555 ! centrosome cycle GO:0007098 16 15 0,000 0,04618424 0,08470794 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,04618424 0,08464045 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,04618424 0,08457306 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,04618424 0,08450578 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,04618424 0,0844386 ! cerebral cortex development GO:0021987 29 15 0,000 0,04618424 0,08437153 ! response to osmotic stress GO:0006970 22 15 0,000 0,04618424 0,08430457 ! vesicle coating GO:0006901 25 15 0,000 0,04618424 0,08423772 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,04618424 0,08417097 ! DNA integration GO:0015074 22 15 0,000 0,04618424 0,08410432 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,04618424 0,08403778 ! peptide secretion GO:0002790 27 15 0,000 0,04618424 0,08397135 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,04618424 0,08390502 ! regulation of vasodilation GO:0042312 24 15 0,000 0,04618424 0,0838388 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,04618424 0,08377268 ! neuron recognition GO:0008038 22 15 0,000 0,04618424 0,08370667 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,04618424 0,08364076 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,04618424 0,08357495 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,04618424 0,08350924 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,04618424 0,08344364 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,04618424 0,08337815 ! biomineral formation GO:0031214 18 15 0,000 0,04618424 0,08331275 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,04618424 0,08324746 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,04618424 0,08318227 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,04618424 0,08311718 ! dopamine metabolic process GO:0042417 30 15 0,000 0,04618424 0,0830522 ! organic cation transport GO:0015695 19 15 0,000 0,04618424 0,08298731 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,04618424 0,08292253 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,04618424 0,08285785 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,04618424 0,08279327 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,04618424 0,08272878 ! defense response to virus GO:0051607 27 15 0,000 0,04618424 0,0826644 ! peptide hormone processing GO:0016486 19 15 0,000 0,04618424 0,08260012 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,04618424 0,08253594 ! protein secretion GO:0009306 27 16 0,000 0,04918761 0,08783502 ! hormone secretion GO:0046879 25 16 0,000 0,04918761 0,08776688 ! bone remodeling GO:0046849 24 16 0,000 0,04918761 0,08769885 ! endothelial cell migration GO:0043542 22 16 0,000 0,04918761 0,08763091 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,04918761 0,08756309 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,04918761 0,08749537 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04918761 0,08742775 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,04918761 0,08736024 ! glial cell development GO:0021782 24 16 0,000 0,04918761 0,08729283 ! patterning of blood vessels GO:0001569 24 16 0,000 0,04918761 0,08722553 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,04918761 0,08715833 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,04918761 0,08709123 ! protein polyubiquitination GO:0000209 26 16 0,000 0,04918761 0,08702424 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,04918761 0,08695735 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,04918761 0,08689056 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,04918761 0,08682388 ! fructose metabolic process GO:0006000 20 16 0,000 0,04918761 0,08675729 ! regulation of protein binding GO:0043393 27 16 0,000 0,04918761 0,08669081 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,04918761 0,08662443 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,04918761 0,08655816 ! protein export from nucleus GO:0006611 24 16 0,000 0,04918761 0,08649198 ! negative regulation of immune response GO:0050777 28 16 0,000 0,04918761 0,08642591 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,04918761 0,08635993 ! DNA replication initiation GO:0006270 25 16 0,000 0,04918761 0,08629406 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,04918761 0,08622829 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,04918761 0,08616261 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,04918761 0,08609704 ! diencephalon development GO:0021536 25 16 0,000 0,04918761 0,08603157 ! oogenesis GO:0048477 23 16 0,000 0,04918761 0,08596619 ! neural crest cell migration GO:0001755 24 16 0,000 0,04918761 0,08590092 ! G1 phase GO:0051318 27 16 0,000 0,04918761 0,08583574 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,04918761 0,08577067 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,04918761 0,08570569 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,04918761 0,08564081 ! steroid catabolic process GO:0006706 22 16 0,000 0,04918761 0,08557603 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,04918761 0,08551135 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,04918761 0,08544676 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,04918761 0,08538227 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,04918761 0,08531788 ! sperm-egg recognition GO:0035036 16 16 0,000 0,04918761 0,08525359 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,04918761 0,08518939 ! nerve development GO:0021675 18 16 0,000 0,04918761 0,08512529 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,04918761 0,08506129 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,04918761 0,08499738 ! negative regulation of translation GO:0017148 22 16 0,000 0,04918761 0,08493357 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,0521817 0,09003594 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,0521817 0,08996844 ! negative regulation of defense response GO:0031348 19 17 0,000 0,0521817 0,08990105 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,0521817 0,08983376 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,0521817 0,08976657 ! glycerol metabolic process GO:0006071 20 17 0,000 0,0521817 0,08969948 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,0521817 0,08963249 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,0521817 0,0895656 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,0521817 0,08949881 ! signal complex assembly GO:0007172 29 17 0,000 0,0521817 0,08943212 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,0521817 0,08936553 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,0521817 0,08929904 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,0521817 0,08923264 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,0521817 0,08916635 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,0521817 0,08910015 ! memory GO:0007613 25 17 0,000 0,0521817 0,08903405 ! keratinization GO:0031424 17 17 0,000 0,0521817 0,08896805 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,0521817 0,08890215 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,0521817 0,08883635 ! retinoid metabolic process GO:0001523 22 17 0,000 0,0521817 0,08877064 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,0521817 0,08870503 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,0521817 0,08863952 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,0521817 0,0885741 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,0521817 0,08850878 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,0521817 0,08844356 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,0521817 0,08837843 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,0521817 0,0883134 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,0521817 0,08824846 ! membrane budding GO:0006900 29 17 0,000 0,0521817 0,08818362 ! heme metabolic process GO:0042168 27 17 0,000 0,0521817 0,08811887 ! actin filament bundle formation GO:0051017 26 17 0,000 0,0521817 0,08805422 ! neuromuscular junction development GO:0007528 23 17 0,000 0,0521817 0,08798967 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,0521817 0,08792521 ! body fluid secretion GO:0007589 27 17 0,000 0,0521817 0,08786084 ! stem cell differentiation GO:0048863 36 17 0,000 0,0521817 0,08779657 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,0521817 0,08773239 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,0521817 0,0876683 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,0521817 0,08760431 ! sensory perception of pain GO:0019233 23 17 0,000 0,0521817 0,08754041 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,0521817 0,08747661 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,0521817 0,0874129 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,0521817 0,08734928 ! synaptogenesis GO:0007416 24 17 0,000 0,0521817 0,08728575 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,0521817 0,08722232 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,0521817 0,08715897 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,0521817 0,08709572 ! cell-cell junction organization GO:0045216 25 17 0,000 0,0521817 0,08703256 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,0521817 0,0869695 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,0521817 0,08690652 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,0521817 0,08684364 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,0521817 0,08678084 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,0521817 0,08671814 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,0521817 0,08665553 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,05516653 0,09154618 ! positive regulation of translation GO:0045727 28 18 0,000 0,05516653 0,09148018 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,05516653 0,09141427 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,05516653 0,09134846 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,05516653 0,09128274 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,05516653 0,09121712 ! cAMP metabolic process GO:0046058 33 18 0,000 0,05516653 0,09115159 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,05516653 0,09108615 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,05516653 0,09102081 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,05516653 0,09095556 ! axis specification GO:0009798 26 18 0,000 0,05516653 0,09089041 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,05516653 0,09082535 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,05516653 0,09076038 ! pancreas development GO:0031016 26 18 0,000 0,05516653 0,0906955 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,05516653 0,09063072 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,05516653 0,09056603 ! glutamine metabolic process GO:0006541 23 18 0,000 0,05516653 0,09050143 ! response to retinoic acid GO:0032526 25 18 0,000 0,05516653 0,09043693 ! pigmentation during development GO:0048066 31 18 0,000 0,05516653 0,09037251 ! central nervous system neuron development GO:0021954 30 18 0,000 0,05516653 0,09030819 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,05516653 0,09024396 ! fucose metabolic process GO:0006004 26 18 0,000 0,05516653 0,09017982 ! response to fungus GO:0009620 19 18 0,000 0,05516653 0,09011577 ! peptide cross-linking GO:0018149 31 18 0,000 0,05516653 0,09005182 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,05516653 0,08998795 ! heart process GO:0003015 27 18 0,000 0,05516653 0,08992417 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,05516653 0,08986049 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,05516653 0,08979689 ! visual learning GO:0008542 35 18 0,000 0,05516653 0,08973339 ! somitogenesis GO:0001756 24 18 0,000 0,05516653 0,08966997 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,05516653 0,08960664 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,05516653 0,08954341 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,05516653 0,08948026 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,05516653 0,0894172 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,05516653 0,08935423 ! vitamin transport GO:0051180 24 18 0,000 0,05516653 0,08929135 ! hormone transport GO:0009914 27 18 0,000 0,05516653 0,08922856 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,05516653 0,08916585 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,05516653 0,08910324 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,05516653 0,08904071 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,05516653 0,08897827 ! cell-cell recognition GO:0009988 20 18 0,000 0,05516653 0,08891591 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,05516653 0,08885365 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,05516653 0,08879147 ! regulation of glucose import GO:0046324 21 18 0,000 0,05516653 0,08872938 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,05516653 0,08866737 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,05516653 0,08860545 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,05516653 0,08854362 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,05516653 0,08848187 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,05814212 0,09318947 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,05814212 0,09312457 ! positive regulation of ossification GO:0045778 30 19 0,000 0,05814212 0,09305977 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,05814212 0,09299505 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,05814212 0,09293043 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,05814212 0,09286589 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,05814212 0,09280145 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,05814212 0,09273709 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,05814212 0,09267282 ! regeneration GO:0031099 32 19 0,000 0,05814212 0,09260864 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,05814212 0,09254456 ! response to alkaloid GO:0043279 32 19 0,000 0,05814212 0,09248056 ! sensory perception of taste GO:0050909 23 19 0,000 0,05814212 0,09241664 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,05814212 0,09235282 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,05814212 0,09228908 ! smooth muscle contraction GO:0006939 36 19 0,000 0,05814212 0,09222544 ! peroxisome organization GO:0007031 29 19 0,000 0,05814212 0,09216188 ! digestive system process GO:0022600 30 19 0,000 0,05814212 0,0920984 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,05814212 0,09203502 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,05814212 0,09197172 ! response to vitamin A GO:0033189 26 19 0,000 0,05814212 0,09190851 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,05814212 0,09184539 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,05814212 0,09178235 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,05814212 0,0917194 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,05814212 0,09165653 ! response to starvation GO:0042594 30 19 0,000 0,05814212 0,09159376 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,05814212 0,09153106 ! plasma membrane fusion GO:0045026 23 19 0,000 0,05814212 0,09146846 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,05814212 0,09140594 ! cytolysis GO:0019835 20 19 0,000 0,05814212 0,0913435 ! renal system process GO:0003014 35 19 0,000 0,05814212 0,09128115 ! vasodilation GO:0042311 33 19 0,000 0,05814212 0,09121888 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,05814212 0,0911567 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,05814212 0,09109461 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,05814212 0,0910326 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,05814212 0,09097067 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,05814212 0,09090883 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,05814212 0,09084707 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,05814212 0,09078539 ! sarcomere organization GO:0045214 23 19 0,000 0,05814212 0,0907238 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,05814212 0,09066229 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,05814212 0,09060087 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,05814212 0,09053953 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,05814212 0,09047827 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,05814212 0,09041709 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,05814212 0,090356 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,05814212 0,09029499 ! protein stabilization GO:0050821 26 19 0,000 0,05814212 0,09023406 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,06110852 0,09477383 ! iron ion transport GO:0006826 37 20 0,000 0,06110852 0,09470997 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,06110852 0,09464619 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,06110852 0,0945825 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,06110852 0,09451889 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,06110852 0,09445537 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,06110852 0,09439194 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,06110852 0,09432859 ! spinal cord development GO:0021510 31 20 0,000 0,06110852 0,09426532 ! response to ethanol GO:0045471 37 20 0,000 0,06110852 0,09420214 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,06110852 0,09413905 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,06110852 0,09407603 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,06110852 0,09401311 ! chromosome condensation GO:0030261 31 20 0,000 0,06110852 0,09395026 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,06110852 0,09388751 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,06110852 0,09382483 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,06110852 0,09376224 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,06110852 0,09369973 ! pallium development GO:0021543 38 20 0,000 0,06110852 0,09363731 ! DNA modification GO:0006304 28 20 0,000 0,06110852 0,09357496 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,06110852 0,0935127 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,06110852 0,09345053 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,06110852 0,09338844 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,06110852 0,09332642 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,06110852 0,0932645 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,06110852 0,09320265 ! collagen catabolic process GO:0030574 25 20 0,000 0,06110852 0,09314088 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,06110852 0,0930792 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,06110852 0,0930176 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,06110852 0,09295608 ! alditol metabolic process GO:0019400 24 20 0,000 0,06110852 0,09289464 ! actin filament-based movement GO:0030048 34 20 0,000 0,06110852 0,09283329 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,06406574 0,09726152 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,06406574 0,09719737 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,06406574 0,0971333 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,06406574 0,09706931 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,06406574 0,0970054 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,06406574 0,09694158 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,06406574 0,09687785 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,06406574 0,0968142 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,06406574 0,09675063 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,06406574 0,09668714 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,06406574 0,09662374 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,06406574 0,09656042 ! protein amino acid acylation GO:0043543 37 21 0,000 0,06406574 0,09649719 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,06406574 0,09643404 ! vesicle docking GO:0048278 27 21 0,000 0,06406574 0,09637097 ! phototransduction GO:0007602 25 21 0,000 0,06406574 0,09630798 ! dendrite development GO:0016358 35 21 0,000 0,06406574 0,09624507 ! visual behavior GO:0007632 39 21 0,000 0,06406574 0,09618225 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,06406574 0,09611951 ! ovarian follicle development GO:0001541 30 21 0,000 0,06406574 0,09605685 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,06406574 0,09599427 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,06406574 0,09593178 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,06406574 0,09586936 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,06406574 0,09580703 ! cell aging GO:0007569 32 21 0,000 0,06406574 0,09574477 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,06406574 0,0956826 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,06406574 0,09562051 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,06406574 0,0955585 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,06406574 0,09549657 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,06406574 0,09543472 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,06406574 0,09537295 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,06406574 0,09531126 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,06406574 0,09524965 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,06406574 0,09518812 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,06406574 0,09512667 ! fatty acid transport GO:0015908 30 21 0,000 0,06406574 0,0950653 ! immunoglobulin production GO:0002377 33 21 0,000 0,06406574 0,095004 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,06406574 0,09494279 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,06406574 0,09488165 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,06406574 0,0948206 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,06406574 0,09475962 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,06406574 0,09469872 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,06406574 0,0946379 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,06406574 0,09457716 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,06406574 0,09451649 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,06406574 0,0944559 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,06406574 0,09439539 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,06406574 0,09433496 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,06406574 0,09427461 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,06406574 0,09421433 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,06406574 0,09415413 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,06406574 0,094094 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,06701382 0,09836106 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,06701382 0,09829833 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,06701382 0,09823568 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,06701382 0,09817311 ! viral genome replication GO:0019079 29 22 0,000 0,06701382 0,09811062 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,06701382 0,09804821 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,06701382 0,09798588 ! leukocyte adhesion GO:0007159 38 22 0,000 0,06701382 0,09792363 ! molting cycle process GO:0022404 40 22 0,000 0,06701382 0,09786145 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,06701382 0,09779936 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,06701382 0,09773734 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,06701382 0,0976754 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,06701382 0,09761354 ! vasculogenesis GO:0001570 33 22 0,000 0,06701382 0,09755176 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,06701382 0,09749006 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,06701382 0,09742844 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,06701382 0,09736689 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,06701382 0,09730542 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,06701382 0,09724403 ! lysosome organization GO:0007040 37 22 0,000 0,06701382 0,09718272 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,06701382 0,09712148 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,06701382 0,09706032 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,06701382 0,09699924 ! regulation of behavior GO:0050795 38 22 0,000 0,06701382 0,09693823 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,06701382 0,0968773 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,06701382 0,09681645 ! membrane depolarization GO:0051899 35 22 0,000 0,06701382 0,09675567 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,06701382 0,09669497 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,06701382 0,09663435 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,06701382 0,0965738 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,06701382 0,09651333 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,06701382 0,09645293 ! blastocyst development GO:0001824 37 22 0,000 0,06701382 0,09639261 ! neural tube closure GO:0001843 33 22 0,000 0,06701382 0,09633237 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,06701382 0,0962722 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,06995278 0,10043158 ! neuron fate commitment GO:0048663 32 23 0,000 0,06995278 0,10036893 ! embryonic pattern specification GO:0009880 31 23 0,000 0,06995278 0,10030636 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,06995278 0,10024386 ! myelination GO:0042552 35 23 0,000 0,06995278 0,10018144 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,06995278 0,1001191 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,06995278 0,10005684 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,06995278 0,09999465 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,06995278 0,09993254 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,06995278 0,09987051 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,06995278 0,09980856 ! vesicle targeting GO:0006903 32 23 0,000 0,06995278 0,09974668 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,06995278 0,09968488 ! osteoblast differentiation GO:0001649 40 23 0,000 0,06995278 0,09962315 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,06995278 0,09956151 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,06995278 0,09949994 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,06995278 0,09943844 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,06995278 0,09937702 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,06995278 0,09931568 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,06995278 0,09925441 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,06995278 0,09919322 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,06995278 0,0991321 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,06995278 0,09907106 ! cell fate determination GO:0001709 45 23 0,000 0,06995278 0,09901009 ! pentose metabolic process GO:0019321 31 23 0,000 0,06995278 0,0989492 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,06995278 0,09888838 ! spermatid development GO:0007286 33 23 0,000 0,06995278 0,09882764 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,06995278 0,09876697 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,06995278 0,09870638 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,06995278 0,09864586 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,06995278 0,09858541 ! telomere organization GO:0032200 32 23 0,000 0,06995278 0,09852504 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,06995278 0,09846475 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,06995278 0,09840452 ! regulation of amine transport GO:0051952 38 23 0,000 0,06995278 0,09834437 ! liver development GO:0001889 40 23 0,000 0,06995278 0,0982843 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,07288265 0,10233828 ! initiation of viral infection GO:0019059 42 24 0,000 0,07288265 0,10227584 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,07288265 0,10221347 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,07288265 0,10215119 ! superoxide metabolic process GO:0006801 32 24 0,000 0,07288265 0,10208897 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,07288265 0,10202684 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,07288265 0,10196478 ! fat cell differentiation GO:0045444 37 24 0,000 0,07288265 0,10190279 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,07288265 0,10184088 ! sperm motility GO:0030317 27 24 0,000 0,07288265 0,10177905 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,07288265 0,10171729 ! vacuole organization GO:0007033 39 24 0,000 0,07288265 0,10165561 ! receptor metabolic process GO:0043112 37 24 0,000 0,07288265 0,101594 ! neural crest cell development GO:0014032 39 24 0,000 0,07288265 0,10153246 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,07288265 0,101471 ! primary neural tube formation GO:0014020 35 24 0,000 0,07288265 0,10140962 ! negative regulation of cell development GO:0010721 56 24 0,000 0,07288265 0,1013483 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,07288265 0,10128707 ! base-excision repair GO:0006284 31 24 0,000 0,07288265 0,1012259 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,07288265 0,10116481 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,07288265 0,1011038 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,07288265 0,10104285 ! glutathione metabolic process GO:0006749 29 24 0,000 0,07288265 0,10098199 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,07288265 0,10092119 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,07288265 0,10086047 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,07288265 0,10079982 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,07580346 0,10477641 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,07580346 0,10471348 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,07580346 0,10465063 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,07580346 0,10458785 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,07580346 0,10452515 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,07580346 0,10446252 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,07580346 0,10439997 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,07580346 0,10433749 ! peptide transport GO:0015833 43 25 0,000 0,07580346 0,10427509 ! male gonad development GO:0008584 33 25 0,000 0,07580346 0,10421276 ! iron ion homeostasis GO:0055072 39 25 0,000 0,07580346 0,10415051 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,07580346 0,10408833 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,07580346 0,10402622 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,07580346 0,10396419 ! phospholipid transport GO:0015914 35 25 0,000 0,07580346 0,10390224 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,07580346 0,10384035 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,07580346 0,10377854 ! detection of light stimulus GO:0009583 30 25 0,000 0,07580346 0,10371681 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,07580346 0,10365514 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,07580346 0,10359355 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,07580346 0,10353204 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,07871523 0,10744512 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,07871523 0,10738139 ! translational initiation GO:0006413 43 26 0,000 0,07871523 0,10731774 ! regulation of pH GO:0006885 36 26 0,000 0,07871523 0,10725416 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,07871523 0,10719066 ! circadian rhythm GO:0007623 42 26 0,000 0,07871523 0,10712724 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,07871523 0,10706388 ! post-embryonic development GO:0009791 42 26 0,000 0,07871523 0,10700061 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,07871523 0,10693741 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,07871523 0,10687428 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,07871523 0,10681123 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,07871523 0,10674825 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,07871523 0,10668534 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,07871523 0,10662251 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,07871523 0,10655976 ! regulation of coagulation GO:0050818 39 26 0,000 0,07871523 0,10649708 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,08161799 0,11035943 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,08161799 0,11029459 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,08161799 0,11022982 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,08161799 0,11016513 ! membrane docking GO:0022406 39 27 0,000 0,08161799 0,11010052 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,08161799 0,11003598 ! catechol metabolic process GO:0009712 43 27 0,000 0,08161799 0,10997152 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,08161799 0,10990714 ! acute-phase response GO:0006953 42 27 0,000 0,08161799 0,10984282 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,08161799 0,10977859 ! myofibril assembly GO:0030239 36 27 0,000 0,08161799 0,10971443 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,08161799 0,10965034 ! response to ionizing radiation GO:0010212 47 27 0,000 0,08161799 0,10958633 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,08161799 0,1095224 ! natural killer cell activation GO:0030101 35 27 0,000 0,08161799 0,10945854 ! lipid oxidation GO:0034440 38 27 0,000 0,08161799 0,10939475 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,08161799 0,10933104 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,08161799 0,1092674 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,08161799 0,10920383 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,08161799 0,10914034 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,08161799 0,10907692 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,08161799 0,10901358 ! gene silencing GO:0016458 41 27 0,000 0,08161799 0,10895031 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,08451178 0,11274773 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,08451178 0,11268237 ! phenol metabolic process GO:0018958 44 28 0,000 0,08451178 0,11261709 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,08451178 0,11255188 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,08451178 0,11248674 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,08451178 0,11242168 ! cell junction assembly GO:0034329 56 28 0,000 0,08451178 0,1123567 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,08451178 0,11229179 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,08451178 0,11222696 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,08451178 0,1121622 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,08451178 0,11209752 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,08451178 0,11203291 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,08451178 0,11196837 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,08451178 0,11190391 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,08451178 0,11183952 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,08451178 0,11177521 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,08451178 0,11171097 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,08451178 0,11164681 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,08451178 0,11158272 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,08451178 0,1115187 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,08451178 0,11145475 ! ensheathment of neurons GO:0007272 43 28 0,000 0,08451178 0,11139088 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,08451178 0,11132709 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,08451178 0,11126336 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,08451178 0,11119971 ! neural tube formation GO:0001841 41 28 0,000 0,08451178 0,11113613 ! placenta development GO:0001890 37 28 0,000 0,08451178 0,11107262 ! regulation of B cell activation GO:0050864 42 28 0,000 0,08451178 0,11100919 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,08739661 0,11473299 ! regulation of innate immune response GO:0045088 38 29 0,000 0,08739661 0,11466754 ! ovulation cycle process GO:0022602 41 29 0,000 0,08739661 0,11460217 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,08739661 0,11453687 ! protein targeting to membrane GO:0006612 53 29 0,000 0,08739661 0,11447164 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,08739661 0,11440649 ! mismatch repair GO:0006298 34 29 0,000 0,08739661 0,11434141 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,08739661 0,11427641 ! muscle cell development GO:0055001 38 29 0,000 0,08739661 0,11421148 ! telencephalon development GO:0021537 52 29 0,000 0,08739661 0,11414662 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,08739661 0,11408184 ! eye morphogenesis GO:0048592 51 29 0,000 0,08739661 0,11401713 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,08739661 0,1139525 ! tissue homeostasis GO:0001894 42 29 0,000 0,08739661 0,11388793 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,09027252 0,11756896 ! collagen metabolic process GO:0032963 40 30 0,000 0,09027252 0,11750243 ! organic anion transport GO:0015711 51 30 0,000 0,09027252 0,11743597 ! cholesterol transport GO:0030301 46 30 0,000 0,09027252 0,11736958 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,09027252 0,11730327 ! spliceosome assembly GO:0000245 49 30 0,000 0,09027252 0,11723703 ! spindle organization GO:0007051 37 30 0,000 0,09027252 0,11717087 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,09027252 0,11710479 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,09027252 0,11703878 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,09027252 0,11697284 ! ceramide metabolic process GO:0006672 43 30 0,000 0,09027252 0,11690698 ! ovulation cycle GO:0042698 43 30 0,000 0,09027252 0,11684119 ! hindbrain development GO:0030902 45 30 0,000 0,09027252 0,11677547 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,09027252 0,11670983 ! adult locomotory behavior GO:0008344 47 30 0,000 0,09027252 0,11664426 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,09027252 0,11657877 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,09027252 0,11651335 ! response to heat GO:0009408 41 30 0,000 0,09027252 0,116448 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,09027252 0,11638273 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,09027252 0,11631753 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,09313952 0,11994452 ! negative regulation of secretion GO:0051048 49 31 0,000 0,09313952 0,1198774 ! glial cell differentiation GO:0010001 55 31 0,000 0,09313952 0,11981035 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,09313952 0,11974338 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,09313952 0,11967648 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,09313952 0,11960966 ! odontogenesis GO:0042476 50 31 0,000 0,09313952 0,11954292 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,09313952 0,11947624 ! segmentation GO:0035282 41 31 0,000 0,09313952 0,11940965 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,09313952 0,11934312 ! metanephros development GO:0001656 58 31 0,000 0,09313952 0,11927667 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,09313952 0,1192103 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,09313952 0,119144 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,09313952 0,11907777 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,09313952 0,11901161 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,09313952 0,11894553 ! RNA modification GO:0009451 40 31 0,000 0,09313952 0,11887953 ! regulation of muscle development GO:0048634 48 32 0,000 0,09599766 0,12245958 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,09599766 0,1223917 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,09599766 0,12232389 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,09599766 0,12225616 ! meiosis I GO:0007127 52 32 0,000 0,09599766 0,1221885 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,09599766 0,12212092 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,09599766 0,12205341 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,09599766 0,12198598 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,09599766 0,12191862 ! peripheral nervous system development GO:0007422 53 32 0,000 0,09599766 0,12185133 ! regulation of protein stability GO:0031647 48 32 0,000 0,09599766 0,12178412 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,09599766 0,12171699 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,09599766 0,12164993 ! cytokine production GO:0001816 44 32 0,000 0,09599766 0,12158294 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,09599766 0,12151603 ! vesicle localization GO:0051648 47 32 0,000 0,09599766 0,12144918 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,09884695 0,12498515 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,09884695 0,12491648 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,09884695 0,12484788 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,09884695 0,12477936 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,09884695 0,12471091 ! sister chromatid segregation GO:0000819 46 33 0,000 0,09884695 0,12464254 ! ear morphogenesis GO:0042471 42 33 0,000 0,09884695 0,12457424 ! actomyosin structure organization GO:0031032 43 33 0,000 0,09884695 0,12450602 ! cell junction organization GO:0034330 63 33 0,000 0,09884695 0,12443787 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,09884695 0,1243698 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,09884695 0,1243018 ! nucleus organization GO:0006997 49 33 0,000 0,09884695 0,12423387 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,09884695 0,12416602 ! female gonad development GO:0008585 49 33 0,000 0,09884695 0,12409825 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,09884695 0,12403054 ! positive regulation of cell development GO:0010720 54 33 0,000 0,09884695 0,12396292 ! lipid homeostasis GO:0055088 55 33 0,000 0,09884695 0,12389536 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,09884695 0,12382788 ! regulation of proteolysis GO:0030162 50 33 0,000 0,09884695 0,12376047 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,09884695 0,12369314 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,09884695 0,12362588 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,09884695 0,12355869 ! cytokinesis GO:0000910 52 33 0,000 0,09884695 0,12349157 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,09884695 0,12342453 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,10168742 0,12690237 ! mRNA catabolic process GO:0006402 48 34 0,000 0,10168742 0,12683356 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,10168742 0,12676481 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,10168742 0,12669614 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,10168742 0,12662755 ! feeding behavior GO:0007631 45 34 0,000 0,10168742 0,12655902 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,10168742 0,12649058 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,10168742 0,1264222 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,10168742 0,1263539 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,10168742 0,12628568 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,10168742 0,12621753 ! neuron migration GO:0001764 46 34 0,000 0,10168742 0,12614945 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,10168742 0,12608144 ! female gamete generation GO:0007292 43 34 0,000 0,10168742 0,12601351 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,10168742 0,12594565 ! polyol metabolic process GO:0019751 44 34 0,000 0,10168742 0,12587787 ! aerobic respiration GO:0009060 47 34 0,000 0,10168742 0,12581015 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,10168742 0,12574251 ! embryonic organ development GO:0048568 45 34 0,000 0,10168742 0,12567495 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,10168742 0,12560745 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,10451911 0,12903593 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,10451911 0,12896671 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,10451911 0,12889756 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,10451911 0,12882848 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,10451911 0,12875948 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,10451911 0,12869055 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,10451911 0,12862169 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,10451911 0,12855291 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,10451911 0,1284842 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,10451911 0,12841557 ! glycogen metabolic process GO:0005977 48 35 0,000 0,10451911 0,12834701 ! pigment metabolic process GO:0042440 61 35 0,000 0,10451911 0,12827852 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,10451911 0,1282101 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,10451911 0,12814176 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,10734202 0,13153258 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,10734202 0,13146254 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,10734202 0,13139258 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,10734202 0,13132269 ! negative regulation of binding GO:0051100 58 36 0,000 0,10734202 0,13125287 ! organic ether metabolic process GO:0018904 46 36 0,000 0,10734202 0,13118313 ! tissue remodeling GO:0048771 62 36 0,000 0,10734202 0,13111347 ! neural tube development GO:0021915 50 36 0,000 0,10734202 0,13104387 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,10734202 0,13097435 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,10734202 0,13090491 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,10734202 0,13083554 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,10734202 0,13076624 ! glucan metabolic process GO:0044042 49 36 0,000 0,10734202 0,13069701 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,1101562 0,13405252 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,1101562 0,13398163 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,1101562 0,13391082 ! learning GO:0007612 67 37 0,000 0,1101562 0,13384008 ! ion transmembrane transport GO:0034220 56 37 0,000 0,1101562 0,13376941 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,1101562 0,13369882 ! regulation of protein secretion GO:0050708 51 37 0,000 0,1101562 0,13362831 ! amino acid activation GO:0043038 52 37 0,000 0,1101562 0,13355787 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,1101562 0,1334875 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,11296167 0,13681509 ! gliogenesis GO:0042063 71 38 0,000 0,11296167 0,13674308 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,11296167 0,13667115 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,11296167 0,13659929 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,11296167 0,13652751 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,11296167 0,1364558 ! phagocytosis GO:0006909 60 38 0,000 0,11296167 0,13638417 ! mesenchymal cell development GO:0014031 64 38 0,000 0,11296167 0,13631262 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,11296167 0,13624114 ! maintenance of location in cell GO:0051651 69 38 0,000 0,11296167 0,13616973 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,11575846 0,13946802 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,11575846 0,139395 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,11575846 0,13932206 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,11575846 0,13924919 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,11575846 0,1391764 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,11575846 0,13910369 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,11575846 0,13903105 ! male sex differentiation GO:0046661 53 39 0,000 0,11575846 0,13895848 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,11575846 0,138886 ! chromatin remodeling GO:0006338 68 39 0,000 0,11575846 0,13881358 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,11575846 0,13874125 ! JNK cascade GO:0007254 54 39 0,000 0,11575846 0,13866899 ! developmental growth GO:0048589 62 39 0,000 0,11575846 0,1385968 ! cell growth GO:0016049 61 39 0,000 0,11575846 0,13852469 ! synapse organization GO:0050808 55 39 0,000 0,11575846 0,13845265 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,11854658 0,14171369 ! response to calcium ion GO:0051592 58 40 0,000 0,11854658 0,14164007 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,11854658 0,14156653 ! regulation of tube size GO:0035150 60 40 0,000 0,11854658 0,14149307 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,11854658 0,14141968 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,11854658 0,14134637 ! peptide metabolic process GO:0006518 56 40 0,000 0,11854658 0,14127313 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,11854658 0,14119997 ! inner ear development GO:0048839 57 40 0,000 0,11854658 0,14112689 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,11854658 0,14105388 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,11854658 0,14098094 ! double-strand break repair GO:0006302 67 40 0,000 0,11854658 0,14090808 ! B cell differentiation GO:0030183 62 40 0,000 0,11854658 0,1408353 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,11854658 0,14076259 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,11854658 0,14068996 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,11854658 0,1406174 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,11854658 0,14054492 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,12132608 0,14376609 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,12132608 0,14369206 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,12132608 0,14361811 ! glucose transport GO:0015758 52 41 0,000 0,12132608 0,14354423 ! endosome transport GO:0016197 71 41 0,000 0,12132608 0,14347043 ! striated muscle contraction GO:0006941 62 41 0,000 0,12132608 0,1433967 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,12132608 0,14332305 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,12132608 0,14324948 ! biopolymer methylation GO:0043414 62 41 0,000 0,12132608 0,14317598 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,12132608 0,14310255 ! mitochondrial transport GO:0006839 60 42 0,000 0,12409697 0,14629576 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,12409697 0,14622081 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,12409697 0,14614594 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,12409697 0,14607115 ! cellular component disassembly GO:0022411 64 42 0,000 0,12409697 0,14599643 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,12409697 0,14592179 ! hexose transport GO:0008645 54 42 0,000 0,12409697 0,14584723 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,12409697 0,14577274 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,12409697 0,14569833 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,12409697 0,14562399 ! excretion GO:0007588 63 42 0,000 0,12409697 0,14554973 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,12409697 0,14547555 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,12409697 0,14540144 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,12409697 0,14532741 ! regulation of cell shape GO:0008360 78 42 0,000 0,12409697 0,14525345 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,12685928 0,14841116 ! leukocyte migration GO:0050900 60 43 0,000 0,12685928 0,14833571 ! neuromuscular process GO:0050905 79 43 0,000 0,12685928 0,14826033 ! activation of caspase activity GO:0006919 65 43 0,000 0,12685928 0,14818504 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,12685928 0,14810981 ! tRNA processing GO:0008033 49 43 0,000 0,12685928 0,14803467 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,12685928 0,1479596 ! vesicle organization GO:0016050 79 43 0,000 0,12685928 0,14788461 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,12685928 0,14780969 ! methylation GO:0032259 64 43 0,000 0,12685928 0,14773485 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,12961303 0,15086537 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,12961303 0,15078906 ! glycolysis GO:0006096 53 44 0,000 0,12961303 0,15071283 ! regulation of action potential GO:0001508 71 44 0,000 0,12961303 0,15063667 ! regulation of ion transport GO:0043269 57 44 0,000 0,12961303 0,15056059 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,12961303 0,15048459 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,12961303 0,15040866 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,12961303 0,15033281 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,12961303 0,15025704 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,12961303 0,15018135 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,12961303 0,15010573 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,12961303 0,15003018 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,12961303 0,14995471 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,13235826 0,15305379 ! RNA catabolic process GO:0006401 64 45 0,000 0,13235826 0,15297688 ! positive regulation of defense response GO:0031349 59 45 0,000 0,13235826 0,15290005 ! regulation of translational initiation GO:0006446 64 45 0,000 0,13235826 0,15282329 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,13235826 0,15274661 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,13235826 0,15267001 ! cell recognition GO:0008037 58 45 0,000 0,13235826 0,15259348 ! cell maturation GO:0048469 60 45 0,000 0,13235826 0,15251703 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,13509499 0,15559262 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,13509499 0,15551475 ! cell redox homeostasis GO:0045454 63 46 0,000 0,13509499 0,15543695 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,13509499 0,15535923 ! regulation of ossification GO:0030278 71 46 0,000 0,13509499 0,15528159 ! histone modification GO:0016570 68 46 0,000 0,13509499 0,15520403 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,13509499 0,15512654 ! response to UV GO:0009411 75 46 0,000 0,13509499 0,15504913 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,13782324 0,15810147 ! viral infectious cycle GO:0019058 71 47 0,000 0,13782324 0,15802265 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,13782324 0,15794392 ! endocrine system development GO:0035270 83 47 0,000 0,13782324 0,15786526 ! covalent chromatin modification GO:0016569 75 47 0,000 0,13782324 0,15778668 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,13782324 0,15770818 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,13782324 0,15762976 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,13782324 0,15755141 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,13782324 0,15747315 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,13782324 0,15739496 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,13782324 0,15731684 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,13782324 0,15723881 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,14054304 0,16026226 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,14054304 0,16018285 ! response to temperature stimulus GO:0009266 62 48 0,000 0,14054304 0,16010351 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,14054304 0,16002425 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,14054304 0,15994507 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,14054304 0,15986597 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,14054304 0,15978694 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,14054304 0,159708 ! regulation of endocytosis GO:0030100 63 48 0,000 0,14054304 0,15962913 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,14054304 0,15955034 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,14054304 0,15947162 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,14325441 0,16246802 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,14325441 0,16238795 ! sensory perception of smell GO:0007608 61 49 0,000 0,14325441 0,16230796 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,14325441 0,16222804 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,14325441 0,1621482 ! RNA elongation GO:0006354 62 49 0,000 0,14325441 0,16206845 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,14325441 0,16198877 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,14325441 0,16190916 ! germ cell development GO:0007281 68 49 0,000 0,14325441 0,16182964 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,14325441 0,1617502 ! cartilage development GO:0051216 70 49 0,000 0,14325441 0,16167083 ! maintenance of location GO:0051235 84 49 0,000 0,14325441 0,16159154 ! regulation of actin filament length GO:0030832 72 50 0,000 0,14595739 0,1645598 ! ear development GO:0043583 72 50 0,000 0,14595739 0,16447918 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,14595739 0,16439863 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,14595739 0,16431816 ! lipid modification GO:0030258 73 50 0,000 0,14595739 0,16423777 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,14595739 0,16415746 ! proton transport GO:0015992 75 50 0,000 0,14595739 0,16407722 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,14595739 0,16399707 ! positive regulation of secretion GO:0051047 71 51 0,000 0,14865199 0,16694316 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,14865199 0,16686168 ! hydrogen transport GO:0006818 77 51 0,000 0,14865199 0,16678029 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,14865199 0,16669897 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,14865199 0,16661773 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,14865199 0,16653657 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,14865199 0,1664555 ! adult behavior GO:0030534 80 51 0,000 0,14865199 0,1663745 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,14865199 0,16629357 ! transition metal ion transport GO:0000041 74 52 0,000 0,15133825 0,16921632 ! regulation of cellular component size GO:0032535 74 52 0,000 0,15133825 0,1691341 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,15133825 0,16905196 ! aging GO:0007568 79 52 0,000 0,15133825 0,16896989 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,15133825 0,16888791 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,15133825 0,168806 ! establishment of organelle localization GO:0051656 85 52 0,000 0,15133825 0,16872418 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,15401619 0,17162656 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,15401619 0,17154345 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,15401619 0,17146042 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,15401619 0,17137747 ! kidney development GO:0001822 90 53 0,000 0,15401619 0,1712946 ! single fertilization GO:0007338 59 53 0,000 0,15401619 0,17121181 ! cell projection assembly GO:0030031 76 53 0,000 0,15401619 0,1711291 ! amino acid transport GO:0006865 84 54 0,000 0,15668582 0,1740113 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,15668582 0,17392731 ! regulation of mitosis GO:0007088 84 54 0,000 0,15668582 0,17384341 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,15668582 0,17375959 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,15668582 0,17367585 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,15668582 0,17359219 ! DNA catabolic process GO:0006308 67 54 0,000 0,15668582 0,17350861 ! detection of external stimulus GO:0009581 66 54 0,000 0,15668582 0,17342512 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,15668582 0,1733417 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,15668582 0,17325836 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,15668582 0,1731751 ! exocytosis GO:0006887 74 55 0,000 0,15934719 0,17603196 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,15934719 0,17594745 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,15934719 0,17586302 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,16200031 0,17870538 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,16200031 0,17861971 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,16464521 0,18144896 ! carbohydrate transport GO:0008643 74 57 0,000 0,16464521 0,18136206 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,16464521 0,18127524 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,16464521 0,1811885 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,16464521 0,18110185 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,16464521 0,18101528 ! camera-type eye development GO:0043010 88 57 0,000 0,16464521 0,1809288 ! secondary metabolic process GO:0019748 84 57 0,000 0,16464521 0,18084239 ! developmental maturation GO:0021700 75 57 0,000 0,16464521 0,18075607 ! gonad development GO:0008406 79 57 0,000 0,16464521 0,18066983 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,16728191 0,18347562 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,16728191 0,18338817 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,16728191 0,1833008 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,16728191 0,18321352 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,16991044 0,18600381 ! lung development GO:0030324 94 59 0,000 0,16991044 0,18591532 ! actin filament organization GO:0007015 95 59 0,000 0,16991044 0,18582691 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,16991044 0,18573859 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,16991044 0,18565036 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,17253082 0,18842397 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,17253082 0,18833454 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,17253082 0,1882452 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,17253082 0,18815594 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,17253082 0,18806677 ! regulation of heart contraction GO:0008016 91 60 0,000 0,17253082 0,18797768 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,17253082 0,18788867 ! fertilization GO:0009566 68 60 0,000 0,17253082 0,18779975 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,17253082 0,18771092 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,17514308 0,19046292 ! meiosis GO:0007126 96 61 0,000 0,17514308 0,19037291 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,17514308 0,19028299 ! urogenital system development GO:0001655 101 61 0,000 0,17514308 0,19019314 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,17514308 0,19010339 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,17514308 0,19001372 ! extracellular matrix organization GO:0030198 103 61 0,000 0,17514308 0,18992413 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,17514308 0,18983463 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,17514308 0,18974521 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,17514308 0,18965588 ! amine catabolic process GO:0009310 90 62 0,000 0,17774724 0,19238525 ! neurotransmitter transport GO:0006836 81 62 0,000 0,17774724 0,19229476 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,17774724 0,19220435 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,17774724 0,19211403 ! respiratory tube development GO:0030323 99 62 0,000 0,17774724 0,19202379 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,17774724 0,19193364 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,17774724 0,19184357 ! meiotic cell cycle GO:0051321 97 62 0,000 0,17774724 0,19175359 ! organelle localization GO:0051640 96 62 0,000 0,17774724 0,19166369 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,18034333 0,19437191 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,18034333 0,19428087 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,18034333 0,19418992 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,18034333 0,19409905 ! regulation of lipase activity GO:0060191 109 63 0,000 0,18034333 0,19400826 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,18293138 0,1967004 ! negative regulation of cell size GO:0045792 108 64 0,000 0,18293138 0,19660849 ! appendage morphogenesis GO:0035107 93 64 0,000 0,18293138 0,19651666 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,18293138 0,19642491 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,18293138 0,19633325 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,18293138 0,19624168 ! hexose catabolic process GO:0019320 82 64 0,000 0,18293138 0,19615019 ! respiratory system development GO:0060541 100 64 0,000 0,18293138 0,19605879 ! adaptive immune response GO:0002250 94 64 0,000 0,18293138 0,19596747 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,18551139 0,19863883 ! regulation of caspase activity GO:0043281 97 65 0,000 0,18551139 0,1985464 ! appendage development GO:0048736 94 65 0,000 0,18551139 0,19845405 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,18551139 0,19836179 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,18551139 0,19826961 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,18551139 0,19817752 ! defense response to bacterium GO:0042742 73 65 0,000 0,18551139 0,19808552 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,18551139 0,1979936 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,18551139 0,19790177 ! activation of immune response GO:0002253 83 65 0,000 0,18551139 0,19781002 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,18808341 0,20045962 ! antigen processing and presentation GO:0019882 96 66 0,000 0,18808341 0,20036677 ! axon guidance GO:0007411 99 66 0,000 0,18808341 0,20027401 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,18808341 0,20018133 ! regulation of immune effector process GO:0002697 101 66 0,000 0,18808341 0,20008874 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,19064746 0,20272268 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,19064746 0,202629 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,19064746 0,20253541 ! acute inflammatory response GO:0002526 92 68 0,000 0,19320355 0,20515613 ! learning or memory GO:0007611 123 68 0,000 0,19320355 0,20506146 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,19320355 0,20496687 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,19320355 0,20487237 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,19320355 0,20477796 ! rhythmic process GO:0048511 105 68 0,000 0,19320355 0,20468364 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,19575172 0,20728774 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,19575172 0,20719234 ! response to drug GO:0042493 108 69 0,000 0,19575172 0,20709704 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,19575172 0,20700182 ! response to metal ion GO:0010038 103 70 0,000 0,19829199 0,20959172 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,19829199 0,20949544 ! humoral immune response GO:0006959 86 70 0,000 0,19829199 0,20939925 ! eye development GO:0001654 111 70 0,000 0,19829199 0,20930316 ! amine transport GO:0015837 101 70 0,000 0,19829199 0,20920714 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,19829199 0,20911122 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,19829199 0,20901539 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,20082438 0,21158775 ! muscle cell differentiation GO:0042692 104 71 0,000 0,20082438 0,21149087 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,20082438 0,21139408 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,20082438 0,21129738 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,20082438 0,21120076 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,20082438 0,21110424 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,20082438 0,2110078 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,20334891 0,21356278 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,20334891 0,21346531 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,20334891 0,21336793 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,20334891 0,21327063 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,20334891 0,21317343 ! negative regulation of transport GO:0051051 116 73 0,000 0,20586561 0,2157134 ! regulation of blood pressure GO:0008217 107 73 0,000 0,20586561 0,21561517 ! tube morphogenesis GO:0035239 118 73 0,000 0,20586561 0,21551703 ! mitochondrion organization GO:0007005 104 73 0,000 0,20586561 0,21541898 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,20586561 0,21532102 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,20586561 0,21522314 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,20837451 0,2177471 ! response to oxygen levels GO:0070482 137 74 0,000 0,20837451 0,21764822 ! digestion GO:0007586 97 74 0,000 0,20837451 0,21754942 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,20837451 0,21745072 ! blood coagulation GO:0007596 116 75 0,000 0,21087563 0,21996097 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,21087563 0,21986126 ! negative regulation of growth GO:0045926 123 75 0,000 0,21087563 0,21976164 ! response to nutrient GO:0007584 104 75 0,000 0,21087563 0,21966211 ! regulation of ligase activity GO:0051340 114 75 0,000 0,21087563 0,21956267 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,21087563 0,21946332 ! amine biosynthetic process GO:0009309 97 76 0,000 0,21336898 0,22195778 ! tRNA metabolic process GO:0006399 95 76 0,000 0,21336898 0,22185744 ! response to unfolded protein GO:0006986 99 76 0,000 0,21336898 0,22175719 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,21336898 0,22165703 ! regulation of protein transport GO:0051223 114 76 0,000 0,21336898 0,22155696 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,2158546 0,22403682 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,2158546 0,22393576 ! sex differentiation GO:0007548 105 77 0,000 0,2158546 0,2238348 ! protein ubiquitination GO:0016567 125 77 0,000 0,2158546 0,22373393 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,2158546 0,22363315 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,2158546 0,22353246 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,2158546 0,22343186 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,21833251 0,22589509 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,21833251 0,22579351 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,21833251 0,22569203 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,22080273 0,22814298 ! cellular respiration GO:0045333 107 79 0,000 0,22080273 0,22804054 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,22080273 0,22793819 ! T cell activation GO:0042110 134 79 0,000 0,22080273 0,22783593 ! regulation of lyase activity GO:0051339 133 79 0,000 0,22080273 0,22773376 ! chromatin assembly GO:0031497 102 80 0,000 0,22326529 0,2301704 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,22326529 0,23006728 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,22326529 0,22996424 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,22326529 0,22986131 ! forebrain development GO:0030900 131 80 0,000 0,22326529 0,22975846 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,2257202 0,23218089 ! hemostasis GO:0007599 125 81 0,000 0,2257202 0,23207709 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,2257202 0,2319734 ! response to protein stimulus GO:0051789 111 81 0,000 0,2257202 0,23186979 ! regulation of neurological system process GO:0031644 122 81 0,000 0,2257202 0,23176628 ! vitamin metabolic process GO:0006766 103 81 0,000 0,2257202 0,23166286 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,2257202 0,23155953 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,2281675 0,23396578 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,2281675 0,23386152 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,2306072 0,23625682 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,2306072 0,23615163 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,2306072 0,23604653 ! regulation of defense response GO:0031347 117 84 0,000 0,23303932 0,23842991 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,23303932 0,2383239 ! sterol metabolic process GO:0016125 120 84 0,000 0,23303932 0,23821798 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,2354639 0,24058951 ! rRNA metabolic process GO:0016072 107 85 0,000 0,2354639 0,24048267 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,2354639 0,24037593 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,2354639 0,24026929 ! regulation of protein localization GO:0032880 132 85 0,000 0,2354639 0,24016274 ! regulation of membrane potential GO:0042391 128 85 0,000 0,2354639 0,24005629 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,2354639 0,23994992 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,23788096 0,24230567 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,23788096 0,24219841 ! nucleosome organization GO:0034728 114 87 0,000 0,24029051 0,24454344 ! cellular defense response GO:0006968 102 87 0,000 0,24029051 0,24443528 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,24029051 0,24432722 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,24029051 0,24421925 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,24029051 0,24411138 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,24269258 0,2464428 ! interphase GO:0051325 159 88 0,000 0,24269258 0,24633404 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,24269258 0,24622538 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,24269258 0,24611681 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,24508719 0,24843567 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,24508719 0,24832623 ! regulation of T cell activation GO:0050863 128 89 0,000 0,24508719 0,24821688 ! leukocyte differentiation GO:0002521 143 90 0,000 0,24747437 0,25052423 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,24747437 0,25041402 ! hormone metabolic process GO:0042445 121 90 0,000 0,24747437 0,25030389 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,25222652 0,25499824 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,25222652 0,2548862 ! positive regulation of immune response GO:0050778 121 92 0,000 0,25222652 0,25477426 ! DNA recombination GO:0006310 146 92 0,000 0,25222652 0,25466242 ! sulfur metabolic process GO:0006790 118 92 0,000 0,25222652 0,25455068 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,25459153 0,25682479 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,25459153 0,25671219 ! electron transport chain GO:0022900 123 94 0,000 0,25694919 0,25897596 ! response to oxidative stress GO:0006979 141 94 0,000 0,25694919 0,25886253 ! angiogenesis GO:0001525 149 95 0,000 0,25929954 0,261116 ! carboxylic acid transport GO:0046942 147 95 0,000 0,25929954 0,26100172 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,26164258 0,26324495 ! in utero embryonic development GO:0001701 147 96 0,000 0,26164258 0,26312984 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,26164258 0,26301484 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,26164258 0,26289993 ! protein maturation GO:0051604 129 96 0,000 0,26164258 0,26278513 ! response to light stimulus GO:0009416 153 96 0,000 0,26164258 0,26267043 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,26397835 0,26489974 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,26397835 0,26478422 ! extracellular structure organization GO:0043062 156 99 0,000 0,26862814 0,26933075 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,26862814 0,26921339 ! regulation of translation GO:0006417 151 100 0,000 0,27094221 0,27141424 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,27094221 0,27129608 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,27094221 0,27117802 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,27094221 0,27106007 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,27094221 0,27094221