pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1182-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 1,05E-10 2,526E-07 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 4,373E-09 5,26E-06 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 1,027E-08 8,239E-06 ! intermediate filament cytoskeleton organization GO:0045104 31 15 3,000 2,819E-08 1,696E-05 ! cell killing GO:0001906 29 15 3,000 2,819E-08 1,356E-05 ! intermediate filament-based process GO:0045103 32 16 3,000 3,752E-08 1,505E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 2,57E-07 8,832E-05 ! regulation of granule cell precursor proliferation GO:0021936 13 7 2,000 3,496E-07 1,051E-04 GO:0021940|positive regulation of granule cell precursor proliferation, ! intermediate filament organization GO:0045109 12 8 2,000 5,585E-07 1,493E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 5,585E-07 1,344E-04 ! spindle organization GO:0007051 46 32 3,000 7,221E-07 1,579E-04 ! ossification GO:0001503 188 90 4,000 1,649E-06 3,305E-04 ! bone development GO:0060348 189 91 4,000 1,741E-06 3,223E-04 ! positive regulation of cell cycle GO:0045787 89 48 3,000 3,806E-06 6,54E-04 ! positive regulation of organelle organization GO:0010638 100 56 3,000 7,09E-06 1,137E-03 ! skin development GO:0043588 36 19 2,000 9,499E-06 1,428E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,116E-05 1,579E-03 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 1,21E-05 1,618E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 1,453E-05 1,84E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,503E-05 1,808E-03 ! sarcomere organization GO:0045214 30 22 2,000 1,503E-05 1,721E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 1,503E-05 1,643E-03 ! leukocyte mediated immunity GO:0002443 128 74 3,000 2,156E-05 2,256E-03 ! positive regulation of nuclear division GO:0051785 40 26 2,000 2,521E-05 2,527E-03 GO:0045840|positive regulation of mitosis, ! positive regulation of phosphorylation GO:0042327 129 79 3,000 2,793E-05 2,688E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,832E-05 2,62E-03 ! muscle cell differentiation GO:0042692 159 80 3,000 2,935E-05 2,615E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 3,082E-05 2,649E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 3,526E-05 2,925E-03 ! myofibril assembly GO:0030239 47 30 2,000 3,912E-05 3,137E-03 GO:0055002|striated muscle cell development, ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 4,71E-05 3,655E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 4,71E-05 3,541E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,71E-05 3,434E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,71E-05 3,333E-03 ! skeletal muscle regeneration GO:0043403 8 5 1,000 4,71E-05 3,238E-03 ! regulation of muscle cell apoptosis GO:0010660 8 5 1,000 4,71E-05 3,148E-03 ! somatic stem cell maintenance GO:0035019 15 5 1,000 4,71E-05 3,063E-03 ! muscle cell development GO:0055001 49 32 2,000 4,764E-05 3,016E-03 ! regulation of microtubule-based process GO:0032886 78 35 2,000 6,257E-05 3,86E-03 ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 7,055E-05 4,243E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 7,055E-05 4,14E-03 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 2,000 7,405E-05 4,242E-03 ! actomyosin structure organization GO:0031032 62 37 2,000 7,405E-05 4,143E-03 ! mammary gland development GO:0030879 86 39 2,000 8,682E-05 4,748E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 9,863E-05 5,273E-03 ! vesicle fusion GO:0006906 17 7 1,000 9,863E-05 5,159E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 9,863E-05 5,049E-03 ! muscle adaptation GO:0043500 14 7 1,000 9,863E-05 4,944E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 9,863E-05 4,843E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 9,863E-05 4,746E-03 ! striated muscle cell differentiation GO:0051146 82 43 2,000 1,165E-04 5,496E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,165E-04 5,391E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,313E-04 5,961E-03 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 1,313E-04 5,851E-03 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 1,335E-04 5,842E-03 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 1,335E-04 5,738E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,686E-04 7,116E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,686E-04 6,994E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,686E-04 6,875E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 21 9 1,000 1,686E-04 6,761E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 1,686E-04 6,65E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,686E-04 6,543E-03 ! gas homeostasis GO:0033483 16 9 1,000 1,686E-04 6,439E-03 ! induction of an organ GO:0001759 14 9 1,000 1,686E-04 6,338E-03 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 2,057E-04 7,615E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 2,104E-04 7,672E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,104E-04 7,557E-03 ! polyamine biosynthetic process GO:0006596 12 10 1,000 2,104E-04 7,446E-03 ! multicellular organism growth GO:0035264 18 10 1,000 2,104E-04 7,338E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,104E-04 7,233E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,104E-04 7,131E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 2,104E-04 7,032E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 2,568E-04 8,465E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,568E-04 8,351E-03 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 2,568E-04 8,24E-03 ! developmental induction GO:0031128 19 11 1,000 2,568E-04 8,131E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of cell migration GO:0030335 126 57 2,000 2,703E-04 8,445E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,078E-04 9,494E-03 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 1,000 3,078E-04 9,374E-03 ! polyamine metabolic process GO:0006595 17 12 1,000 3,078E-04 9,256E-03 ! gland morphogenesis GO:0022612 29 12 1,000 3,078E-04 9,142E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 3,303E-04 9,693E-03 ! lipid localization GO:0010876 28 13 1,000 3,632E-04 0,01052913 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 3,632E-04 0,01040378 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 1,000 3,632E-04 0,01028138 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,632E-04 0,01016183 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 3,632E-04 0,01004503 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,632E-04 9,931E-03 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 3,632E-04 9,819E-03 ! regulation of mitosis GO:0007088 105 63 2,000 3,634E-04 9,714E-03 GO:0051783|regulation of nuclear division, ! positive regulation of cell motion GO:0051272 146 64 2,000 3,806E-04 0,01006375 ! myotube differentiation GO:0014902 25 14 1,000 4,232E-04 0,01106662 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 4,232E-04 0,01094762 ! stem cell development GO:0048864 43 14 1,000 4,232E-04 0,01083116 GO:0019827|stem cell maintenance, ! heterophilic cell adhesion GO:0007157 39 15 1,000 4,876E-04 0,01234845 ! response to cAMP GO:0051591 22 15 1,000 4,876E-04 0,01221982 ! regulation of vasodilation GO:0042312 26 15 1,000 4,876E-04 0,01209384 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 4,876E-04 0,01197043 ! tissue regeneration GO:0042246 26 15 1,000 4,876E-04 0,01184952 ! water homeostasis GO:0030104 27 15 1,000 4,876E-04 0,01173102 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 5,564E-04 0,01325537 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 1,000 5,564E-04 0,01312542 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 5,564E-04 0,01299799 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 5,564E-04 0,01287301 ! activation of MAPKK activity GO:0000186 35 16 1,000 5,564E-04 0,01275041 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 5,564E-04 0,01263012 GO:0031114|regulation of microtubule depolymerization, ! biomineral formation GO:0031214 20 16 1,000 5,564E-04 0,01251208 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 6,297E-04 0,0140292 ! myoblast differentiation GO:0045445 45 17 1,000 6,297E-04 0,01390049 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,297E-04 0,01377412 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 6,297E-04 0,01365003 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 6,297E-04 0,01352816 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 6,8E-04 0,01447817 ! activation of protein kinase activity GO:0032147 147 79 2,000 7,057E-04 0,0148944 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,075E-04 0,0148012 ! memory GO:0007613 31 18 1,000 7,075E-04 0,0146736 ! epidermis morphogenesis GO:0048730 40 18 1,000 7,075E-04 0,01454819 ! cell-substrate junction assembly GO:0007044 54 18 1,000 7,075E-04 0,0144249 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 7,075E-04 0,01430368 ! lipid phosphorylation GO:0046834 35 19 1,000 7,896E-04 0,01583084 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 7,896E-04 0,01570001 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 7,896E-04 0,01557132 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 8,761E-04 0,01713655 GO:0010675|regulation of cellular carbohydrate metabolic process, ! stem cell differentiation GO:0048863 53 20 1,000 8,761E-04 0,01699836 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 8,761E-04 0,01686237 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 8,761E-04 0,01672854 ! response to inorganic substance GO:0010035 153 86 2,000 9,034E-04 0,01711452 ! tube morphogenesis GO:0035239 176 86 2,000 9,034E-04 0,01698082 ! gland development GO:0048732 206 88 2,000 9,657E-04 0,01801058 ! inactivation of MAPK activity GO:0000188 39 21 1,000 9,669E-04 0,01789521 ! regulation of vasoconstriction GO:0019229 39 21 1,000 9,669E-04 0,01775861 ! collagen fibril organization GO:0030199 59 21 1,000 9,669E-04 0,01762407 ! regulation of cell cycle process GO:0010564 149 90 2,000 1,031E-03 0,01864344 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 1,062E-03 0,01907015 ! regeneration GO:0031099 41 22 1,000 1,062E-03 0,01892889 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 1,062E-03 0,01878971 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 1,062E-03 0,01865256 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 1,133E-03 0,01975442 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,162E-03 0,02010661 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 1,162E-03 0,01996299 ! leukocyte adhesion GO:0007159 50 23 1,000 1,162E-03 0,01982141 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 1,162E-03 0,01968182 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,265E-03 0,02129082 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,265E-03 0,02114297 ! vesicle docking GO:0048278 47 24 1,000 1,265E-03 0,02099716 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 1,265E-03 0,02085334 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 1,265E-03 0,02071148 GO:0002708|positive regulation of lymphocyte mediated immunity, ! membrane depolarization GO:0051899 39 24 1,000 1,265E-03 0,02057154 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,265E-03 0,02043347 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,357E-03 0,02176264 GO:0060538|skeletal muscle organ development, ! vasculogenesis GO:0001570 46 25 1,000 1,374E-03 0,02188518 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 1,374E-03 0,02174119 ! proteoglycan biosynthetic process GO:0030166 50 25 1,000 1,374E-03 0,02159909 ! regulation of blood coagulation GO:0030193 40 25 1,000 1,374E-03 0,02145884 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,486E-03 0,02306449 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,486E-03 0,02291664 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 1,486E-03 0,02277067 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 1,602E-03 0,02440218 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 1,602E-03 0,02424871 ! dendrite development GO:0016358 59 28 1,000 1,723E-03 0,02591416 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 1,848E-03 0,02762181 ! regulation of coagulation GO:0050818 46 29 1,000 1,848E-03 0,02745131 ! membrane docking GO:0022406 61 30 1,000 1,978E-03 0,02919043 ! cell junction assembly GO:0034329 78 30 1,000 1,978E-03 0,02901244 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 1,978E-03 0,02883661 ! collagen metabolic process GO:0032963 45 31 1,000 2,111E-03 0,03059642 ! cholesterol homeostasis GO:0042632 53 31 1,000 2,111E-03 0,03041321 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 1,000 2,111E-03 0,03023218 ! positive regulation of immune effector process GO:0002699 67 31 1,000 2,111E-03 0,03005329 ! response to hydrogen peroxide GO:0042542 50 32 1,000 2,249E-03 0,03182332 ! proteoglycan metabolic process GO:0006029 63 32 1,000 2,249E-03 0,03163722 ! cholesterol transport GO:0030301 56 32 1,000 2,249E-03 0,03145328 ! response to mechanical stimulus GO:0009612 57 32 1,000 2,249E-03 0,03127147 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 2,249E-03 0,03109175 ! positive regulation of catabolic process GO:0009896 64 32 1,000 2,249E-03 0,03091408 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 2,39E-03 0,03267541 ! cell fate specification GO:0001708 52 33 1,000 2,39E-03 0,03249081 ! sterol transport GO:0015918 57 33 1,000 2,39E-03 0,03230827 ! leukocyte chemotaxis GO:0030595 50 33 1,000 2,39E-03 0,03212778 GO:0060326|cell chemotaxis, ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 2,536E-03 0,03389826 ! glial cell differentiation GO:0010001 63 34 1,000 2,536E-03 0,03371097 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 2,536E-03 0,03352575 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 2,536E-03 0,03334255 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 2,686E-03 0,03512153 ! negative regulation of secretion GO:0051048 63 35 1,000 2,686E-03 0,03493169 ! odontogenesis GO:0042476 66 35 1,000 2,686E-03 0,03474388 ! neutral lipid metabolic process GO:0006638 50 35 1,000 2,686E-03 0,03455808 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 2,686E-03 0,03437427 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 2,84E-03 0,03615267 ! cell junction organization GO:0034330 86 36 1,000 2,84E-03 0,0359624 ! tissue remodeling GO:0048771 76 37 1,000 2,998E-03 0,03776505 ! glycerol ether metabolic process GO:0006662 53 37 1,000 2,998E-03 0,03756835 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 2,998E-03 0,0373737 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 3,16E-03 0,03919136 ! lipid homeostasis GO:0055088 67 38 1,000 3,16E-03 0,03899038 ! organic ether metabolic process GO:0018904 55 39 1,000 3,326E-03 0,04083067 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 3,326E-03 0,04062341 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 3,496E-03 0,04248558 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 3,496E-03 0,04227209 ! gliogenesis GO:0042063 88 41 1,000 3,67E-03 0,04415541 ! response to reactive oxygen species GO:0000302 67 42 1,000 3,849E-03 0,04606755 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 3,849E-03 0,04583949 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 3,849E-03 0,04561368 ! regulation of protein secretion GO:0050708 71 42 1,000 3,849E-03 0,04539008 ! epithelial cell differentiation GO:0030855 79 43 1,000 4,031E-03 0,04730531 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 4,031E-03 0,04707568 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 4,217E-03 0,04901003 ! developmental growth GO:0048589 82 44 1,000 4,217E-03 0,04877441 ! leukocyte migration GO:0050900 68 45 1,000 4,406E-03 0,05072725 ! cell growth GO:0016049 84 45 1,000 4,406E-03 0,05048569 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 4,6E-03 0,05245642 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 4,6E-03 0,05220898 ! response to insulin stimulus GO:0032868 95 46 1,000 4,6E-03 0,05196387 ! response to calcium ion GO:0051592 81 47 1,000 4,798E-03 0,05394375 ! positive regulation of DNA binding GO:0043388 73 47 1,000 4,798E-03 0,05369285 ! regulation of adaptive immune response GO:0002819 84 47 1,000 4,798E-03 0,05344427 ! protein homooligomerization GO:0051260 76 47 1,000 4,798E-03 0,05319798 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 5,205E-03 0,05744565 ! positive regulation of cytokine production GO:0001819 86 50 1,000 5,414E-03 0,0594822 ! positive regulation of binding GO:0051099 78 51 1,000 5,627E-03 0,06154197 ! response to estrogen stimulus GO:0043627 93 51 1,000 5,627E-03 0,0612635 ! embryonic skeletal system development GO:0048706 85 51 1,000 5,627E-03 0,06098754 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 5,627E-03 0,06071405 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 5,627E-03 0,06044301 ! vesicle organization GO:0016050 107 51 1,000 5,627E-03 0,06017437 ! regulation of muscle contraction GO:0006937 81 52 1,000 5,844E-03 0,06221683 ! membrane fusion GO:0006944 110 52 1,000 5,844E-03 0,06194275 ! regulation of protein polymerization GO:0032271 103 53 1,000 6,065E-03 0,06399944 ! response to UV GO:0009411 104 53 1,000 6,065E-03 0,06371997 ! activation of phospholipase C activity GO:0007202 103 54 1,000 6,289E-03 0,06579043 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 6,289E-03 0,06550562 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 6,289E-03 0,06522327 ! sulfur compound biosynthetic process GO:0044272 93 55 1,000 6,517E-03 0,06729932 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 6,517E-03 0,06701171 ! skeletal muscle fiber development GO:0048741 111 56 1,000 6,749E-03 0,06910067 ! regulation of DNA replication GO:0006275 101 56 1,000 6,749E-03 0,06880787 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 6,985E-03 0,07090932 ! muscle fiber development GO:0048747 112 57 1,000 6,985E-03 0,07061139 ! lipid modification GO:0030258 97 57 1,000 6,985E-03 0,07031594 ! regulation of phospholipase activity GO:0010517 106 57 1,000 6,985E-03 0,07002296 ! positive regulation of lipase activity GO:0060193 108 58 1,000 7,224E-03 0,07212139 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 7,467E-03 0,07423907 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 7,714E-03 0,07637559 ! kidney development GO:0001822 122 60 1,000 7,714E-03 0,07606257 ! regulation of protein complex assembly GO:0043254 117 61 1,000 7,964E-03 0,07821001 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 8,475E-03 0,08289423 ! extracellular matrix organization GO:0030198 133 66 1,000 9,27E-03 0,09029382 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 9,541E-03 0,09256677 ! activation of MAPK activity GO:0000187 115 67 1,000 9,541E-03 0,09219501 ! lung development GO:0030324 144 67 1,000 9,541E-03 0,09182623 ! positive regulation of T cell activation GO:0050870 109 67 1,000 9,541E-03 0,09146039 ! negative regulation of kinase activity GO:0033673 131 68 1,000 9,817E-03 0,09372634 ! regulation of lipase activity GO:0060191 130 68 1,000 9,817E-03 0,09335588 ! urogenital system development GO:0001655 137 69 1,000 0,01009558 0,09562982 ! respiratory tube development GO:0030323 150 70 1,000 0,01037794 0,09791893 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,01066378 0,10022288 ! regulation of immune effector process GO:0002697 137 71 1,000 0,01066378 0,09983291 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01091007 0,10174273 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01091007 0,1013499 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01091007 0,1009601 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01091007 0,10057327 ! neuron fate determination GO:0048664 7 5 0,000 0,01091007 0,10018941 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01091007 0,09980846 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01091007 0,0994304 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01091007 0,09905519 ! polyol transport GO:0015791 12 5 0,000 0,01091007 0,0986828 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01091007 0,0983132 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01091007 0,09794636 ! response to superoxide GO:0000303 10 5 0,000 0,01091007 0,09758225 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01091007 0,09722083 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01091007 0,09686208 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01091007 0,09650597 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01091007 0,09615247 ! female meiosis GO:0007143 7 5 0,000 0,01091007 0,09580155 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01091007 0,09545318 ! cobalt ion transport GO:0006824 11 5 0,000 0,01091007 0,09510734 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01091007 0,09476399 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01091007 0,09442311 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01091007 0,09408468 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01091007 0,09374866 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01091007 0,09341503 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01091007 0,09308378 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01091007 0,09275486 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01091007 0,09242826 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01091007 0,09210395 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01091007 0,0917819 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01091007 0,09146211 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01091007 0,09114453 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01091007 0,09082915 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01091007 0,09051595 ! negative chemotaxis GO:0050919 14 5 0,000 0,01091007 0,0902049 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01091007 0,08989598 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01091007 0,08958916 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01091007 0,08928444 ! behavioral response to pain GO:0048266 9 5 0,000 0,01091007 0,08898178 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01091007 0,08868116 ! Notch receptor processing GO:0007220 8 5 0,000 0,01091007 0,08838257 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01091007 0,08808599 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01091007 0,08779139 ! micturition GO:0060073 9 5 0,000 0,01091007 0,08749875 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01091007 0,08720806 ! copulation GO:0007620 9 5 0,000 0,01091007 0,08691929 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01091007 0,08663242 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01091007 0,08634745 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01091007 0,08606434 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01091007 0,08578309 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01091007 0,08550366 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01091007 0,08522605 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01091007 0,08495024 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01091007 0,08467621 ! grooming behavior GO:0007625 6 5 0,000 0,01091007 0,08440394 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01091007 0,08413341 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01091007 0,08386462 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01091007 0,08359753 ! response to protozoan GO:0001562 10 5 0,000 0,01091007 0,08333214 ! lymph vessel development GO:0001945 10 5 0,000 0,01091007 0,08306843 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01091007 0,08280639 ! endochondral ossification GO:0001958 16 5 0,000 0,01091007 0,08254599 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01091007 0,08228722 ! parathyroid gland development GO:0060017 13 5 0,000 0,01091007 0,08203008 ! anagen GO:0042640 6 5 0,000 0,01091007 0,08177453 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01091007 0,08152057 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01091007 0,08126819 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01091007 0,08101736 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01091007 0,08076808 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01091007 0,08052032 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01091007 0,08027408 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01091007 0,08002934 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01091007 0,07978609 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01091007 0,07954432 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01091007 0,079304 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01091007 0,07906513 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01091007 0,0788277 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01091007 0,07859169 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01091007 0,07835709 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01091007 0,07812388 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01091007 0,07789206 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01091007 0,07766161 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01091007 0,07743252 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01091007 0,07720478 ! histidine catabolic process GO:0006548 6 5 0,000 0,01091007 0,07697837 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01091007 0,07675329 ! microvillus organization GO:0032528 7 5 0,000 0,01091007 0,07652952 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01091007 0,07630705 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01091007 0,07608587 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01091007 0,07586597 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01091007 0,07564733 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01091007 0,07542996 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01091007 0,07521382 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01091007 0,07499893 ! polyol catabolic process GO:0046174 7 5 0,000 0,01091007 0,07478526 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01091007 0,0745728 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01091007 0,07436154 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01091007 0,07415148 ! muscle cell migration GO:0014812 8 5 0,000 0,01091007 0,0739426 ! mitochondrial fission GO:0000266 8 5 0,000 0,01091007 0,0737349 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01091007 0,07352836 ! mRNA transcription GO:0009299 9 5 0,000 0,01091007 0,07332297 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01091007 0,07311873 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01091007 0,07291562 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01091007 0,07271364 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01091007 0,07251278 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01091007 0,07231302 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01091007 0,07211435 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01091007 0,07191678 ! response to food GO:0032094 6 5 0,000 0,01091007 0,07172029 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01091007 0,07152486 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01091007 0,0713305 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01091007 0,07113719 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01091007 0,07094493 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01091007 0,07075371 ! forebrain neuron development GO:0021884 13 5 0,000 0,01091007 0,07056351 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01091007 0,07037433 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01091007 0,07018616 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01091007 0,069999 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01091007 0,06981283 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01091007 0,06962765 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01091007 0,06944345 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01091007 0,06926022 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01091007 0,06907796 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01091007 0,06889665 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01091007 0,0687163 ! basic amino acid transport GO:0015802 11 5 0,000 0,01091007 0,06853688 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01091007 0,0683584 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01091007 0,06818084 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01091007 0,06800421 ! depyrimidination GO:0045008 10 5 0,000 0,01091007 0,06782849 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01091007 0,06765367 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01091007 0,06747976 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01091007 0,06730673 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01091007 0,06713459 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01091007 0,06696333 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01091007 0,06679294 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01091007 0,06662341 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01091007 0,06645475 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01091007 0,06628693 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01091007 0,06611996 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01091007 0,06595383 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01091007 0,06578853 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01091007 0,06562406 ! response to arsenic GO:0046685 10 5 0,000 0,01091007 0,06546041 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01091007 0,06529757 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01091007 0,06513555 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01091007 0,06497432 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01091007 0,06481389 ! response to cadmium ion GO:0046686 7 5 0,000 0,01091007 0,06465425 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01091007 0,06449539 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01091007 0,06433732 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01091007 0,06418001 ! decidualization GO:0046697 11 5 0,000 0,01091007 0,06402347 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01091007 0,0638677 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01091007 0,06371268 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01091007 0,06355841 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01091007 0,06340489 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01091007 0,06325211 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01091007 0,06310006 ! neural tube patterning GO:0021532 7 5 0,000 0,01091007 0,06294874 ! embryonic cleavage GO:0040016 6 5 0,000 0,01091007 0,06279815 ! peroxisome fission GO:0016559 5 5 0,000 0,01091007 0,06264827 ! histone demethylation GO:0016577 10 5 0,000 0,01091007 0,06249911 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01091007 0,06235065 ! mitotic recombination GO:0006312 9 5 0,000 0,01091007 0,0622029 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01091007 0,06205585 ! metaphase plate congression GO:0051310 7 5 0,000 0,01091007 0,06190949 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01091007 0,06176382 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01091007 0,06161884 ! enteric nervous system development GO:0048484 8 5 0,000 0,01091007 0,06147453 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01091007 0,0613309 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01091007 0,06118794 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01091007 0,06104564 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01091007 0,060904 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01091007 0,06076302 ! plasminogen activation GO:0031639 5 5 0,000 0,01091007 0,06062269 ! B cell homeostasis GO:0001782 13 5 0,000 0,01091007 0,06048301 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01091007 0,06034396 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01091007 0,06020556 ! metaphase GO:0051323 8 5 0,000 0,01091007 0,06006779 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01091007 0,05993065 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01091007 0,05979413 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01091007 0,05965824 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01091007 0,05952296 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01091007 0,05938829 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01091007 0,05925423 ! response to redox state GO:0051775 5 5 0,000 0,01091007 0,05912078 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01091007 0,05898792 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01091007 0,05885566 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01091007 0,05872399 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01091007 0,05859291 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01091007 0,05846242 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01091007 0,0583325 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01091007 0,05820316 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01091007 0,05807439 ! striatum development GO:0021756 9 5 0,000 0,01091007 0,05794619 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01091007 0,05781856 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01091007 0,05769148 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01091007 0,05756497 ! glial cell migration GO:0008347 11 5 0,000 0,01091007 0,057439 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01091007 0,05731359 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01091007 0,05718872 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01091007 0,0570644 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01091007 0,05694062 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01091007 0,05681737 ! neuroprotection GO:0043526 6 5 0,000 0,01091007 0,05669465 ! neural plate development GO:0001840 8 5 0,000 0,01091007 0,05657247 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01091007 0,05645081 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01091007 0,05632967 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01091007 0,05620905 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01091007 0,05608894 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01091007 0,05596935 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01091007 0,05585027 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01091007 0,05573169 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01091007 0,05561361 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01091007 0,05549604 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01091007 0,05537896 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01091007 0,05526237 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01091007 0,05514627 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01091007 0,05503066 ! drug metabolic process GO:0017144 6 5 0,000 0,01091007 0,05491553 ! stem cell division GO:0017145 11 5 0,000 0,01091007 0,05480089 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01091007 0,05468672 ! organ regeneration GO:0031100 7 5 0,000 0,01091007 0,05457302 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01091007 0,0544598 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01091007 0,05434705 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01091007 0,05423476 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01095309 0,05433634 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,01095309 0,05422454 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,01095309 0,05411319 ! respiratory system development GO:0060541 153 72 1,000 0,01095309 0,05400231 ! learning or memory GO:0007611 147 73 1,000 0,01124584 0,0553323 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01184164 0,05814486 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,01214465 0,05951124 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01214465 0,05939028 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01245104 0,06076512 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,01276081 0,0621508 ! protein oligomerization GO:0051259 139 78 1,000 0,01276081 0,06202525 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01307392 0,06341908 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01307797 0,06331107 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01307797 0,06318394 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01307797 0,06305732 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01307797 0,06293121 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01307797 0,06280559 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01307797 0,06268048 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01307797 0,06255587 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01307797 0,06243175 ! sleep GO:0030431 13 6 0,000 0,01307797 0,06230812 ! response to oxygen radical GO:0000305 11 6 0,000 0,01307797 0,06218499 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01307797 0,06206233 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01307797 0,06194016 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01307797 0,06181847 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01307797 0,06169726 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01307797 0,06157652 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01307797 0,06145626 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01307797 0,06133646 ! forebrain regionalization GO:0021871 8 6 0,000 0,01307797 0,06121713 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01307797 0,06109826 ! male meiosis GO:0007140 7 6 0,000 0,01307797 0,06097985 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01307797 0,0608619 ! response to zinc ion GO:0010043 9 6 0,000 0,01307797 0,06074441 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01307797 0,06062737 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01307797 0,06051077 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01307797 0,06039463 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01307797 0,06027893 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01307797 0,06016368 ! malate metabolic process GO:0006108 11 6 0,000 0,01307797 0,06004886 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01307797 0,05993448 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01307797 0,05982054 ! protein refolding GO:0042026 15 6 0,000 0,01307797 0,05970703 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01307797 0,05959394 ! opsonization GO:0008228 8 6 0,000 0,01307797 0,05948129 ! mating behavior GO:0007617 7 6 0,000 0,01307797 0,05936906 ! neuron remodeling GO:0016322 15 6 0,000 0,01307797 0,05925726 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01307797 0,05914587 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01307797 0,0590349 ! equilibrioception GO:0050957 14 6 0,000 0,01307797 0,05892435 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01307797 0,05881421 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01307797 0,05870448 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01307797 0,05859516 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01307797 0,05848625 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01307797 0,05837774 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01307797 0,05826963 ! toxin metabolic process GO:0009404 11 6 0,000 0,01307797 0,05816193 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01307797 0,05805462 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01307797 0,0579477 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01307797 0,05784118 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01307797 0,05773505 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01307797 0,05762931 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01307797 0,05752395 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01307797 0,05741898 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01307797 0,05731439 ! thymic T cell selection GO:0045061 12 6 0,000 0,01307797 0,05721019 ! protein lipoylation GO:0009249 10 6 0,000 0,01307797 0,05710636 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01307797 0,0570029 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01307797 0,05689982 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01307797 0,05679712 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01307797 0,05669478 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01307797 0,05659281 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01307797 0,05649121 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01307797 0,05638997 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01307797 0,05628909 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01307797 0,05618858 ! hyperosmotic response GO:0006972 9 6 0,000 0,01307797 0,05608842 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01307797 0,05598862 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01307797 0,05588917 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01307797 0,05579008 ! urea metabolic process GO:0019627 7 6 0,000 0,01307797 0,05569133 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01307797 0,05559294 ! neutrophil activation GO:0042119 8 6 0,000 0,01307797 0,05549489 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01307797 0,05539719 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01307797 0,05529983 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01307797 0,05520281 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01307797 0,05510613 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01307797 0,05500979 ! neuron apoptosis GO:0051402 9 6 0,000 0,01307797 0,05491379 ! nucleoside salvage GO:0043174 9 6 0,000 0,01307797 0,05481812 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01307797 0,05472279 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01307797 0,05462778 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01307797 0,05453311 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01307797 0,05443876 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01307797 0,05434474 ! carnitine transport GO:0015879 10 6 0,000 0,01307797 0,05425104 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01307797 0,05415766 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01307797 0,05406461 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01307797 0,05397187 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01307797 0,05387946 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01307797 0,05378735 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01307797 0,05369557 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01307797 0,05360409 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01307797 0,05351293 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01307797 0,05342208 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01307797 0,05333153 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01307797 0,05324129 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01307797 0,05315136 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01307797 0,05306172 ! neural nucleus development GO:0048857 14 6 0,000 0,01307797 0,05297239 ! response to UV-C GO:0010225 11 6 0,000 0,01307797 0,05288337 ! astrocyte development GO:0014002 15 6 0,000 0,01307797 0,05279464 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01307797 0,0527062 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01307797 0,05261806 ! interaction with symbiont GO:0051702 13 6 0,000 0,01307797 0,05253022 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01307797 0,05244267 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01307797 0,05235541 ! response to copper ion GO:0046688 10 6 0,000 0,01307797 0,05226844 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01307797 0,05218176 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01307797 0,05209537 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01307797 0,05200926 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01307797 0,05192344 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01307797 0,0518379 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01307797 0,05175264 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01307797 0,05166766 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01307797 0,05158296 ! hair follicle maturation GO:0048820 7 6 0,000 0,01307797 0,05149853 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01307797 0,05141438 ! Schwann cell development GO:0014044 15 6 0,000 0,01307797 0,05133051 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01307797 0,05124691 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01307797 0,05116358 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01307797 0,05108052 ! subpallium development GO:0021544 10 6 0,000 0,01307797 0,05099774 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01307797 0,05091521 ! histone ubiquitination GO:0016574 8 6 0,000 0,01307797 0,05083296 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01307797 0,05075097 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01307797 0,05066925 ! G2 phase GO:0051319 16 6 0,000 0,01307797 0,05058779 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01307797 0,05050659 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01307797 0,05042565 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01307797 0,05034496 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01307797 0,05026454 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01307797 0,05018437 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01307797 0,05010446 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01307797 0,05002481 ! receptor internalization GO:0031623 10 6 0,000 0,01307797 0,0499454 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01307797 0,04986625 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01307797 0,04978735 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01307797 0,04970869 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01307797 0,04963029 ! protein deubiquitination GO:0016579 14 6 0,000 0,01307797 0,04955213 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01307797 0,04947422 ! protein destabilization GO:0031648 9 6 0,000 0,01307797 0,04939655 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01307797 0,04931913 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01307797 0,04924194 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01307797 0,049165 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01307797 0,0490883 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01307797 0,04901184 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01307797 0,04893562 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01307797 0,04885963 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01307797 0,04878388 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01307797 0,04870836 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01307797 0,04863308 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01307797 0,04855803 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01307797 0,04848321 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01307797 0,04840862 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01307797 0,04833426 ! catecholamine transport GO:0051937 9 6 0,000 0,01307797 0,04826013 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01307797 0,04818622 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01307797 0,04811254 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01307797 0,04803909 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01307797 0,04796586 ! maternal placenta development GO:0001893 12 6 0,000 0,01307797 0,04789285 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01307797 0,04782006 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01307797 0,0477475 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01307797 0,04767516 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01307797 0,04760303 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01307797 0,04753112 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01307797 0,04745943 ! response to metal ion GO:0010038 140 80 1,000 0,01339038 0,04851997 ! response to hypoxia GO:0001666 171 81 1,000 0,01371016 0,04960399 ! response to nutrient GO:0007584 125 82 1,000 0,01403325 0,0506967 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01403325 0,05062069 ! response to oxygen levels GO:0070482 176 83 1,000 0,01435963 0,05172047 ! negative regulation of transport GO:0051051 153 84 1,000 0,01468929 0,05282874 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,0150222 0,05394541 GO:0002696|positive regulation of leukocyte activation, ! tRNA transcription GO:0009304 14 7 0,000 0,0152412 0,05465025 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0152412 0,05456893 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0152412 0,05448785 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0152412 0,054407 ! regulation of helicase activity GO:0051095 15 7 0,000 0,0152412 0,0543264 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0152412 0,05424604 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0152412 0,05416591 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0152412 0,05408602 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0152412 0,05400636 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0152412 0,05392694 ! prostate gland development GO:0030850 13 7 0,000 0,0152412 0,05384775 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0152412 0,0537688 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0152412 0,05369007 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0152412 0,05361158 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0152412 0,05353332 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0152412 0,05345528 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0152412 0,05337747 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0152412 0,05329988 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,0152412 0,05322253 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0152412 0,05314539 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0152412 0,05306848 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0152412 0,05299179 ! glycolipid transport GO:0046836 10 7 0,000 0,0152412 0,05291533 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0152412 0,05283908 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0152412 0,05276305 ! neuron adhesion GO:0007158 12 7 0,000 0,0152412 0,05268724 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,0152412 0,05261165 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0152412 0,05253628 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0152412 0,05246112 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0152412 0,05238617 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0152412 0,05231144 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0152412 0,05223692 ! mRNA stabilization GO:0048255 18 7 0,000 0,0152412 0,05216262 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,0152412 0,05208852 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0152412 0,05201464 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0152412 0,05194096 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0152412 0,0518675 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0152412 0,05179424 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0152412 0,05172119 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0152412 0,05164834 ! lipoprotein transport GO:0042953 14 7 0,000 0,0152412 0,0515757 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0152412 0,05150326 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0152412 0,05143102 ! rhythmic behavior GO:0007622 15 7 0,000 0,0152412 0,05135899 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0152412 0,05128716 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0152412 0,05121553 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0152412 0,0511441 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0152412 0,05107287 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0152412 0,05100184 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0152412 0,050931 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0152412 0,05086036 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0152412 0,05078992 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0152412 0,05071967 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0152412 0,05064961 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0152412 0,05057975 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0152412 0,05051008 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0152412 0,05044061 ! spinal cord patterning GO:0021511 13 7 0,000 0,0152412 0,05037132 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0152412 0,05030222 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0152412 0,05023332 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0152412 0,0501646 ! adrenal gland development GO:0030325 17 7 0,000 0,0152412 0,05009607 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0152412 0,05002772 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0152412 0,04995957 ! ovulation GO:0030728 9 7 0,000 0,0152412 0,04989159 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0152412 0,04982381 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0152412 0,0497562 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0152412 0,04968878 ! microtubule nucleation GO:0007020 20 7 0,000 0,0152412 0,04962154 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0152412 0,04955449 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0152412 0,04948761 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0152412 0,04942092 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0152412 0,0493544 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0152412 0,04928807 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0152412 0,04922191 ! galactose metabolic process GO:0006012 13 7 0,000 0,0152412 0,04915593 ! response to dietary excess GO:0002021 8 7 0,000 0,0152412 0,04909012 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0152412 0,04902449 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0152412 0,04895904 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0152412 0,04889376 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0152412 0,04882866 ! organ growth GO:0035265 15 7 0,000 0,0152412 0,04876372 ! purine salvage GO:0043101 10 7 0,000 0,0152412 0,04869897 ! nucleoside transport GO:0015858 8 7 0,000 0,0152412 0,04863438 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0152412 0,04856996 ! parturition GO:0007567 14 7 0,000 0,0152412 0,04850572 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0152412 0,04844164 ! rRNA modification GO:0000154 14 7 0,000 0,0152412 0,04837773 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0152412 0,04831399 ! spindle checkpoint GO:0031577 15 7 0,000 0,0152412 0,04825042 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0152412 0,04818702 ! macrophage differentiation GO:0030225 11 7 0,000 0,0152412 0,04812378 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0152412 0,04806071 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0152412 0,0479978 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0152412 0,04793506 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0152412 0,04787248 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,0152412 0,04781007 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0152412 0,04774781 ! fibrinolysis GO:0042730 10 7 0,000 0,0152412 0,04768572 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0152412 0,04762379 ! eating behavior GO:0042755 7 7 0,000 0,0152412 0,04756202 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0152412 0,04750042 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0152412 0,04743897 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0152412 0,04737768 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0152412 0,04731654 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0152412 0,04725557 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0152412 0,04719475 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0152412 0,04713409 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0152412 0,04707358 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0152412 0,04701323 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0152412 0,04695304 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0152412 0,04689299 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0152412 0,0468331 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0152412 0,04677337 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0152412 0,04671378 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0152412 0,04665435 ! regulation of meiosis GO:0040020 12 7 0,000 0,0152412 0,04659507 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0152412 0,04653594 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0152412 0,04647696 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0152412 0,04641813 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0152412 0,04635944 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0152412 0,04630091 ! transcription termination GO:0006353 13 7 0,000 0,0152412 0,04624252 ! response to tumor cell GO:0002347 13 7 0,000 0,0152412 0,04618428 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,0152412 0,04612619 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0152412 0,04606824 ! anaphase GO:0051322 17 7 0,000 0,0152412 0,04601044 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0152412 0,04595278 ! axonal fasciculation GO:0007413 18 7 0,000 0,0152412 0,04589527 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0152412 0,0458379 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0152412 0,04578068 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0152412 0,04572359 ! diuresis GO:0030146 12 7 0,000 0,0152412 0,04566665 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0152412 0,04560985 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0152412 0,04555319 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0152412 0,04549668 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0152412 0,0454403 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0152412 0,04538406 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0152412 0,04532796 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0152412 0,045272 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0152412 0,04521618 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0152412 0,04516049 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0152412 0,04510495 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0152412 0,04504953 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0152412 0,04499426 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0152412 0,04493912 ! lymph node development GO:0048535 10 7 0,000 0,0152412 0,04488411 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0152412 0,04482924 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0152412 0,04477451 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0152412 0,0447199 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0152412 0,04466543 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0152412 0,0446111 ! adult feeding behavior GO:0008343 9 7 0,000 0,0152412 0,04455689 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0152412 0,04450282 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0152412 0,04444887 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0152412 0,04439506 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0152412 0,04434138 ! retina homeostasis GO:0001895 12 7 0,000 0,0152412 0,04428783 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0152412 0,0442344 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0152412 0,04418111 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0152412 0,04412794 ! protein prenylation GO:0018342 18 7 0,000 0,0152412 0,0440749 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0152412 0,04402199 ! amine biosynthetic process GO:0009309 138 86 1,000 0,01535837 0,04430723 ! regulation of protein transport GO:0051223 154 87 1,000 0,01569776 0,0452321 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,01604037 0,04616402 ! regulation of DNA binding GO:0051101 155 88 1,000 0,01604037 0,04610887 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01739975 0,04995681 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01739975 0,04989726 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01739975 0,04983786 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01739975 0,0497786 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01739975 0,04971948 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01739975 0,0496605 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01739975 0,04960166 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01739975 0,04954296 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01739975 0,0494844 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01739975 0,04942598 ! meiotic prophase I GO:0007128 13 8 0,000 0,01739975 0,04936769 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01739975 0,04930954 ! oligopeptide transport GO:0006857 15 8 0,000 0,01739975 0,04925153 ! UTP metabolic process GO:0046051 8 8 0,000 0,01739975 0,04919366 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01739975 0,04913592 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01739975 0,04907832 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01739975 0,04902085 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01739975 0,04896351 ! succinate metabolic process GO:0006105 14 8 0,000 0,01739975 0,04890631 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01739975 0,04884925 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01739975 0,04879231 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01739975 0,04873551 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01739975 0,04867884 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01739975 0,0486223 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01739975 0,0485659 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01739975 0,04850962 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01739975 0,04845348 ! reflex GO:0060004 16 8 0,000 0,01739975 0,04839746 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01739975 0,04834157 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01739975 0,04828582 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01739975 0,04823019 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01739975 0,04817469 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01739975 0,04811931 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01739975 0,04806407 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01739975 0,04800895 ! pigment granule organization GO:0048753 16 8 0,000 0,01739975 0,04795396 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01739975 0,04789909 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01739975 0,04784435 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01739975 0,04778973 ! histidine metabolic process GO:0006547 16 8 0,000 0,01739975 0,04773524 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01739975 0,04768087 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01739975 0,04762662 ! glycine catabolic process GO:0006546 13 8 0,000 0,01739975 0,0475725 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01739975 0,04751851 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01739975 0,04746463 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01739975 0,04741088 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01739975 0,04735724 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01739975 0,04730373 ! melanin metabolic process GO:0006582 15 8 0,000 0,01739975 0,04725034 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01739975 0,04719707 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01739975 0,04714392 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01739975 0,04709089 ! macrophage activation GO:0042116 12 8 0,000 0,01739975 0,04703798 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01739975 0,04698519 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01739975 0,04693251 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01739975 0,04687996 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01739975 0,04682752 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01739975 0,0467752 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01739975 0,04672299 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01739975 0,04667091 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01739975 0,04661893 ! osteoblast development GO:0002076 16 8 0,000 0,01739975 0,04656708 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01739975 0,04651534 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01739975 0,04646371 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01739975 0,0464122 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01739975 0,0463608 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01739975 0,04630952 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01739975 0,04625835 ! response to UV-B GO:0010224 16 8 0,000 0,01739975 0,04620729 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01739975 0,04615634 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01739975 0,04610551 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01739975 0,04605479 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01739975 0,04600418 ! cellular extravasation GO:0045123 12 8 0,000 0,01739975 0,04595368 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01739975 0,04590329 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01739975 0,04585302 ! response to antibiotic GO:0046677 11 8 0,000 0,01739975 0,04580285 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01739975 0,04575279 ! DNA topological change GO:0006265 12 8 0,000 0,01739975 0,04570284 ! response to tropane GO:0014073 15 8 0,000 0,01739975 0,045653 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01739975 0,04560327 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01739975 0,04555365 ! melanosome transport GO:0032402 13 8 0,000 0,01739975 0,04550413 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01739975 0,04545473 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01739975 0,04540543 ! mast cell activation GO:0045576 14 8 0,000 0,01739975 0,04535623 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01739975 0,04530715 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01739975 0,04525817 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01739975 0,04520929 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01739975 0,04516052 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01739975 0,04511186 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01739975 0,0450633 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01739975 0,04501484 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01739975 0,04496649 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01739975 0,04491824 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01739975 0,0448701 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01739975 0,04482206 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01739975 0,04477412 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01739975 0,04472629 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01739975 0,04467855 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01739975 0,04463092 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01739975 0,04458339 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01739975 0,04453596 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01739975 0,04448863 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01739975 0,0444414 ! hormone catabolic process GO:0042447 17 8 0,000 0,01739975 0,04439428 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01739975 0,04434725 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01739975 0,04430032 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01739975 0,04425349 ! ATP catabolic process GO:0006200 11 8 0,000 0,01739975 0,04420676 ! blastocyst growth GO:0001832 19 8 0,000 0,01739975 0,04416013 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01739975 0,0441136 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01739975 0,04406716 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01739975 0,04402082 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01739975 0,04397458 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01739975 0,04392844 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01739975 0,04388239 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01739975 0,04383644 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01739975 0,04379059 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01739975 0,04374483 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01739975 0,04369917 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01739975 0,0436536 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01739975 0,04360813 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01739975 0,04356275 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01739975 0,04351747 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01739975 0,04347228 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01739975 0,04342718 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01739975 0,04338218 ! regulation of membrane potential GO:0042391 164 93 1,000 0,01780109 0,04433687 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,01780109 0,04429102 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,01816267 0,04514398 ! regulation of T cell activation GO:0050863 158 94 1,000 0,01816267 0,04509739 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01852735 0,04595547 ! positive regulation of immune response GO:0050778 156 96 1,000 0,01889513 0,04681945 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,01926599 0,04768927 ! regulation of protein localization GO:0032880 176 97 1,000 0,01926599 0,04764025 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01955365 0,04830192 ! axon extension GO:0048675 15 9 0,000 0,01955365 0,04825238 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01955365 0,04820294 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01955365 0,04815361 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01955365 0,04810437 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01955365 0,04805523 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01955365 0,0480062 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01955365 0,04795726 ! phosphate transport GO:0006817 19 9 0,000 0,01955365 0,04790843 ! reproductive behavior GO:0019098 19 9 0,000 0,01955365 0,04785969 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01955365 0,04781105 ! CTP metabolic process GO:0046036 9 9 0,000 0,01955365 0,04776251 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01955365 0,04771407 ! GTP metabolic process GO:0046039 9 9 0,000 0,01955365 0,04766573 ! RNA methylation GO:0001510 15 9 0,000 0,01955365 0,04761748 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01955365 0,04756934 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01955365 0,04752129 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01955365 0,04747333 ! artery development GO:0060840 24 9 0,000 0,01955365 0,04742548 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01955365 0,04737772 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01955365 0,04733005 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01955365 0,04728249 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01955365 0,04723501 ! chemosensory behavior GO:0007635 20 9 0,000 0,01955365 0,04718764 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01955365 0,04714035 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01955365 0,04709317 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01955365 0,04704607 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01955365 0,04699907 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01955365 0,04695217 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01955365 0,04690536 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01955365 0,04685864 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01955365 0,04681201 ! protein targeting to ER GO:0045047 22 9 0,000 0,01955365 0,04676548 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01955365 0,04671904 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01955365 0,04667269 ! T cell selection GO:0045058 23 9 0,000 0,01955365 0,04662644 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01955365 0,04658027 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01955365 0,0465342 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01955365 0,04648822 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01955365 0,04644232 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01955365 0,04639652 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01955365 0,04635081 ! mannose metabolic process GO:0006013 13 9 0,000 0,01955365 0,04630519 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01955365 0,04625966 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01955365 0,04621422 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01955365 0,04616887 ! receptor clustering GO:0043113 18 9 0,000 0,01955365 0,0461236 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01955365 0,04607843 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01955365 0,04603334 ! ruffle organization GO:0031529 15 9 0,000 0,01955365 0,04598834 ! retinol metabolic process GO:0042572 18 9 0,000 0,01955365 0,04594343 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01955365 0,04589861 ! behavioral fear response GO:0001662 22 9 0,000 0,01955365 0,04585387 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01955365 0,04580922 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01955365 0,04576466 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01955365 0,04572019 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01955365 0,0456758 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01955365 0,0456315 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01955365 0,04558728 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01955365 0,04554315 ! segment specification GO:0007379 13 9 0,000 0,01955365 0,0454991 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01955365 0,04545514 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01955365 0,04541127 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01955365 0,04536748 ! response to amine stimulus GO:0014075 13 9 0,000 0,01955365 0,04532377 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01955365 0,04528015 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01955365 0,04523661 ! erythrocyte development GO:0048821 15 9 0,000 0,01955365 0,04519315 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01955365 0,04514978 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01955365 0,04510649 ! renal water homeostasis GO:0003091 14 9 0,000 0,01955365 0,04506329 ! postreplication repair GO:0006301 22 9 0,000 0,01955365 0,04502017 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01955365 0,04497713 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01955365 0,04493417 ! icosanoid secretion GO:0032309 15 9 0,000 0,01955365 0,04489129 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01955365 0,0448485 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01955365 0,04480578 ! regulation of cell division GO:0051302 15 9 0,000 0,01955365 0,04476315 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01955365 0,0447206 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01955365 0,04467813 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01955365 0,04463574 ! sterol catabolic process GO:0016127 11 9 0,000 0,01955365 0,04459344 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01955365 0,04455121 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01955365 0,04450906 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01955365 0,04446699 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01955365 0,044425 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01955365 0,04438309 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01955365 0,04434126 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01955365 0,0442995 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01955365 0,04425783 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01955365 0,04421624 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01955365 0,04417472 ! purine base metabolic process GO:0006144 21 9 0,000 0,01955365 0,04413328 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01955365 0,04409192 ! pigment granule transport GO:0051904 17 9 0,000 0,01955365 0,04405063 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01955365 0,04400942 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01955365 0,04396829 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01955365 0,04392724 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01955365 0,04388626 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01955365 0,04384536 ! mitochondrion localization GO:0051646 15 9 0,000 0,01955365 0,04380454 ! response to virus GO:0009615 160 98 1,000 0,01963991 0,04395686 ! interphase GO:0051325 213 98 1,000 0,01963991 0,04391601 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02170289 0,0484839 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02170289 0,04843892 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02170289 0,04839403 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02170289 0,04834922 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02170289 0,04830449 ! synapsis GO:0007129 13 10 0,000 0,02170289 0,04825985 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02170289 0,04821529 ! N-glycan processing GO:0006491 20 10 0,000 0,02170289 0,04817081 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02170289 0,04812641 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02170289 0,0480821 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02170289 0,04803786 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02170289 0,04799371 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02170289 0,04794964 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02170289 0,04790565 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02170289 0,04786174 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02170289 0,04781791 ! androgen metabolic process GO:0008209 17 10 0,000 0,02170289 0,04777416 ! phospholipid efflux GO:0033700 16 10 0,000 0,02170289 0,04773049 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02170289 0,0476869 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02170289 0,04764339 ! lung alveolus development GO:0048286 26 10 0,000 0,02170289 0,04759996 ! pathogenesis GO:0009405 13 10 0,000 0,02170289 0,04755661 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02170289 0,04751334 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02170289 0,04747014 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02170289 0,04742703 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02170289 0,04738399 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02170289 0,04734103 ! endoderm development GO:0007492 16 10 0,000 0,02170289 0,04729815 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02170289 0,04725535 ! arginine catabolic process GO:0006527 13 10 0,000 0,02170289 0,04721262 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02170289 0,04716997 ! proline metabolic process GO:0006560 13 10 0,000 0,02170289 0,0471274 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02170289 0,0470849 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02170289 0,04704248 ! V(D)J recombination GO:0033151 28 10 0,000 0,02170289 0,04700014 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02170289 0,04695787 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02170289 0,04691568 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02170289 0,04687357 ! B cell proliferation GO:0042100 18 10 0,000 0,02170289 0,04683153 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02170289 0,04678957 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02170289 0,04674768 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02170289 0,04670586 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02170289 0,04666413 ! epithelial cell development GO:0002064 20 10 0,000 0,02170289 0,04662246 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02170289 0,04658087 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02170289 0,04653936 ! macroautophagy GO:0016236 17 10 0,000 0,02170289 0,04649791 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02170289 0,04645655 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02170289 0,04641525 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02170289 0,04637403 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02170289 0,04633288 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02170289 0,04629181 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02170289 0,0462508 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02170289 0,04620987 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02170289 0,04616902 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02170289 0,04612823 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02170289 0,04608752 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02170289 0,04604688 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02170289 0,04600631 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02170289 0,04596581 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02170289 0,04592538 ! response to dsRNA GO:0043331 20 10 0,000 0,02170289 0,04588502 ! DNA ligation GO:0006266 19 10 0,000 0,02170289 0,04584474 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02170289 0,04580452 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02170289 0,04576438 ! melanosome localization GO:0032400 16 10 0,000 0,02170289 0,04572431 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02170289 0,0456843 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02170289 0,04564437 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02170289 0,0456045 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02170289 0,04556471 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02170289 0,04552498 ! mRNA cleavage GO:0006379 17 10 0,000 0,02170289 0,04548533 ! protein sumoylation GO:0016925 15 10 0,000 0,02170289 0,04544574 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02170289 0,04540622 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02170289 0,04536677 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02170289 0,04532739 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02170289 0,04528808 ! salivary gland development GO:0007431 27 10 0,000 0,02170289 0,04524884 ! prophase GO:0051324 15 10 0,000 0,02170289 0,04520966 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02170289 0,04517055 ! apical protein localization GO:0045176 15 10 0,000 0,02170289 0,04513151 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02170289 0,04509254 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02170289 0,04505363 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02170289 0,04501479 ! midbrain development GO:0030901 13 10 0,000 0,02170289 0,04497602 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02170289 0,04493731 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02170289 0,04489867 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02170289 0,0448601 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02170289 0,04482159 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02170289 0,04478315 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02170289 0,04474478 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02170289 0,04470647 ! detection of calcium ion GO:0005513 23 10 0,000 0,02170289 0,04466823 ! oocyte development GO:0048599 17 10 0,000 0,02170289 0,04463005 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02170289 0,04459194 ! blastocyst formation GO:0001825 17 10 0,000 0,02170289 0,04455389 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02170289 0,04451591 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02170289 0,04447799 ! activation of innate immune response GO:0002218 12 10 0,000 0,02170289 0,04444013 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02170289 0,04440234 ! response to nicotine GO:0035094 20 10 0,000 0,02170289 0,04436462 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02170289 0,04432696 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02170289 0,04428936 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02170289 0,04425183 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0238475 0,04858347 ! respiratory burst GO:0045730 17 11 0,000 0,0238475 0,04854236 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0238475 0,04850133 ! neuron fate specification GO:0048665 17 11 0,000 0,0238475 0,04846037 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0238475 0,04841947 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0238475 0,04837865 ! thyroid gland development GO:0030878 26 11 0,000 0,0238475 0,04833789 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0238475 0,0482972 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0238475 0,04825658 ! response to pain GO:0048265 24 11 0,000 0,0238475 0,04821603 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0238475 0,04817555 ! T cell proliferation GO:0042098 26 11 0,000 0,0238475 0,04813513 ! blood vessel remodeling GO:0001974 29 11 0,000 0,0238475 0,04809478 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0238475 0,0480545 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,0238475 0,04801429 ! bone resorption GO:0045453 16 11 0,000 0,0238475 0,04797414 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,0238475 0,04793406 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0238475 0,04789405 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0238475 0,04785411 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0238475 0,04781423 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0238475 0,04777442 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0238475 0,04773467 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0238475 0,04769499 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0238475 0,04765538 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0238475 0,04761583 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0238475 0,04757635 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,0238475 0,04753693 ! lipid digestion GO:0044241 18 11 0,000 0,0238475 0,04749758 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0238475 0,04745829 ! UV protection GO:0009650 19 11 0,000 0,0238475 0,04741907 ! adult heart development GO:0007512 14 11 0,000 0,0238475 0,04737991 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0238475 0,04734082 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0238475 0,04730179 ! temperature homeostasis GO:0001659 17 11 0,000 0,0238475 0,04726283 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0238475 0,04722393 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0238475 0,04718509 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0238475 0,04714632 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0238475 0,04710762 ! regulation of organ growth GO:0046620 13 11 0,000 0,0238475 0,04706897 ! pigment granule localization GO:0051875 20 11 0,000 0,0238475 0,04703039 ! vasoconstriction GO:0042310 18 11 0,000 0,0238475 0,04699187 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0238475 0,04695342 ! embryonic axis specification GO:0000578 18 11 0,000 0,0238475 0,04691502 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0238475 0,0468767 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0238475 0,04683843 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0238475 0,04680022 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0238475 0,04676208 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0238475 0,046724 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0238475 0,04668598 ! zymogen activation GO:0031638 15 11 0,000 0,0238475 0,04664803 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0238475 0,04661013 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0238475 0,0465723 ! nucleosome positioning GO:0016584 15 11 0,000 0,0238475 0,04653453 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0238475 0,04649682 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0238475 0,04645917 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0238475 0,04642158 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,0238475 0,04638405 ! acid secretion GO:0046717 18 11 0,000 0,0238475 0,04634659 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0238475 0,04630918 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0238475 0,04627183 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0238475 0,04623455 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0238475 0,04619732 ! oocyte differentiation GO:0009994 18 11 0,000 0,0238475 0,04616016 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0238475 0,04612305 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0238475 0,046086 ! cholesterol efflux GO:0033344 19 11 0,000 0,0238475 0,04604902 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0238475 0,04601209 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0238475 0,04597522 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0238475 0,04593841 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0238475 0,04590166 ! embryonic gut development GO:0048566 15 11 0,000 0,0238475 0,04586497 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0238475 0,04582833 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0238475 0,04579176 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0238475 0,04575524 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0238475 0,04571879 ! defense response to fungus GO:0050832 13 11 0,000 0,0238475 0,04568238 ! lysogeny GO:0030069 21 11 0,000 0,0238475 0,04564604 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0238475 0,04560976 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0238475 0,04557353 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0238475 0,04553736 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0238475 0,04550125 ! regulation of embryonic development GO:0045995 27 11 0,000 0,0238475 0,04546519 ! nucleus localization GO:0051647 19 11 0,000 0,0238475 0,0454292 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0238475 0,04539326 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02598747 0,04942755 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02598747 0,04938851 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02598747 0,04934953 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02598747 0,04931061 ! virus-host interaction GO:0019048 29 12 0,000 0,02598747 0,04927175 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02598747 0,04923296 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02598747 0,04919422 ! cartilage condensation GO:0001502 20 12 0,000 0,02598747 0,04915555 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02598747 0,04911693 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02598747 0,04907838 ! protein complex disassembly GO:0043241 27 12 0,000 0,02598747 0,04903989 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02598747 0,04900145 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02598747 0,04896308 ! hippocampus development GO:0021766 26 12 0,000 0,02598747 0,04892477 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02598747 0,04888652 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02598747 0,04884832 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02598747 0,04881019 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02598747 0,04877212 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02598747 0,0487341 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02598747 0,04869615 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02598747 0,04865825 ! drug transport GO:0015893 16 12 0,000 0,02598747 0,04862041 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02598747 0,04858264 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02598747 0,04854492 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02598747 0,04850726 ! focal adhesion formation GO:0048041 35 12 0,000 0,02598747 0,04846965 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02598747 0,04843211 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02598747 0,04839462 ! forebrain cell migration GO:0021885 21 12 0,000 0,02598747 0,0483572 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02598747 0,04831982 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02598747 0,04828251 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02598747 0,04824526 ! entry into host cell GO:0030260 32 12 0,000 0,02598747 0,04820806 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02598747 0,04817092 ! monoamine transport GO:0015844 18 12 0,000 0,02598747 0,04813384 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02598747 0,04809681 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02598747 0,04805984 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02598747 0,04802293 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02598747 0,04798607 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02598747 0,04794927 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02598747 0,04791253 ! protein homotetramerization GO:0051289 21 12 0,000 0,02598747 0,04787584 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02598747 0,04783921 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02598747 0,04780264 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02598747 0,04776612 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02598747 0,04772966 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02598747 0,04769325 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02598747 0,0476569 ! cranial nerve development GO:0021545 20 12 0,000 0,02598747 0,0476206 ! fucose catabolic process GO:0019317 22 12 0,000 0,02598747 0,04758436 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02598747 0,04754818 ! histone acetylation GO:0016573 26 12 0,000 0,02598747 0,04751205 ! histone methylation GO:0016571 26 12 0,000 0,02598747 0,04747597 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02598747 0,04743995 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02598747 0,04740398 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02598747 0,04736807 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02598747 0,04733221 ! T cell homeostasis GO:0043029 25 12 0,000 0,02598747 0,04729641 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02598747 0,04726066 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02598747 0,04722496 ! spleen development GO:0048536 22 12 0,000 0,02598747 0,04718932 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02598747 0,04715374 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02598747 0,0471182 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02598747 0,04708272 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02598747 0,04704729 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02598747 0,04701192 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02598747 0,0469766 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02598747 0,04694133 ! response to cold GO:0009409 17 12 0,000 0,02598747 0,04690612 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02598747 0,04687095 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02598747 0,04683585 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02812282 0,05064634 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02812282 0,05060846 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02812282 0,05057064 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02812282 0,05053287 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02812282 0,05049516 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02812282 0,05045751 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02812282 0,05041991 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02812282 0,05038236 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02812282 0,05034488 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02812282 0,05030745 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02812282 0,05027007 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02812282 0,05023275 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02812282 0,05019549 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02812282 0,05015828 ! methionine metabolic process GO:0006555 27 13 0,000 0,02812282 0,05012112 ! plasma membrane organization GO:0007009 24 13 0,000 0,02812282 0,05008402 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02812282 0,05004698 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02812282 0,05000999 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02812282 0,04997305 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02812282 0,04993617 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02812282 0,04989935 ! response to X-ray GO:0010165 25 13 0,000 0,02812282 0,04986258 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02812282 0,04982586 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02812282 0,04978919 ! exocrine system development GO:0035272 32 13 0,000 0,02812282 0,04975258 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02812282 0,04971603 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02812282 0,04967953 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02812282 0,04964308 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02812282 0,04960668 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02812282 0,04957034 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02812282 0,04953405 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02812282 0,04949782 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02812282 0,04946163 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02812282 0,0494255 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02812282 0,04938943 ! ribosome assembly GO:0042255 17 13 0,000 0,02812282 0,0493534 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02812282 0,04931743 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02812282 0,04928151 ! chromatin silencing GO:0006342 26 13 0,000 0,02812282 0,04924564 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02812282 0,04920983 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02812282 0,04917407 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02812282 0,04913835 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02812282 0,0491027 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02812282 0,04906709 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02812282 0,04903153 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02812282 0,04899603 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02812282 0,04896058 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02812282 0,04892517 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02812282 0,04888982 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02812282 0,04885452 ! embryonic placenta development GO:0001892 23 13 0,000 0,02812282 0,04881927 ! insulin secretion GO:0030073 23 13 0,000 0,02812282 0,04878408 ! actin filament polymerization GO:0030041 24 13 0,000 0,02812282 0,04874893 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02812282 0,04871383 ! acrosome reaction GO:0007340 18 13 0,000 0,02812282 0,04867879 ! rRNA transcription GO:0009303 25 14 0,000 0,03025357 0,05232932 ! lactation GO:0007595 26 14 0,000 0,03025357 0,05229173 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03025357 0,05225419 ! reproductive cellular process GO:0048610 20 14 0,000 0,03025357 0,0522167 ! tRNA modification GO:0006400 20 14 0,000 0,03025357 0,05217927 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03025357 0,05214189 ! regulation of S phase GO:0033261 23 14 0,000 0,03025357 0,05210457 ! water transport GO:0006833 21 14 0,000 0,03025357 0,0520673 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 25 14 0,000 0,03025357 0,05203008 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03025357 0,05199292 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03025357 0,05195581 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03025357 0,05191875 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03025357 0,05188174 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03025357 0,05184479 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03025357 0,05180789 ! palate development GO:0060021 31 14 0,000 0,03025357 0,05177104 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03025357 0,05173425 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03025357 0,0516975 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03025357 0,05166081 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03025357 0,05162417 ! arginine metabolic process GO:0006525 17 14 0,000 0,03025357 0,05158759 ! regulation of heart rate GO:0002027 24 14 0,000 0,03025357 0,05155105 ! organic alcohol transport GO:0015850 29 14 0,000 0,03025357 0,05151457 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03025357 0,05147813 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03025357 0,05144175 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03025357 0,05140543 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03025357 0,05136915 ! L-amino acid transport GO:0015807 30 14 0,000 0,03025357 0,05133292 ! bone mineralization GO:0030282 17 14 0,000 0,03025357 0,05129675 ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03025357 0,05126062 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03025357 0,05122455 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03025357 0,05118853 ! cerebellum development GO:0021549 21 14 0,000 0,03025357 0,05115255 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03025357 0,05111663 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03025357 0,05108076 ! response to gamma radiation GO:0010332 28 14 0,000 0,03025357 0,05104494 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03025357 0,05100917 ! cofactor transport GO:0051181 26 14 0,000 0,03025357 0,05097345 ! NADP metabolic process GO:0006739 24 14 0,000 0,03025357 0,05093778 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03025357 0,05090216 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03025357 0,05086658 ! intestinal absorption GO:0050892 25 14 0,000 0,03025357 0,05083106 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03025357 0,05079559 ! oxygen transport GO:0015671 21 14 0,000 0,03025357 0,05076017 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03025357 0,0507248 ! male genitalia development GO:0030539 24 14 0,000 0,03025357 0,05068947 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03025357 0,0506542 ! regulation of axon extension GO:0030516 37 14 0,000 0,03025357 0,05061897 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03025357 0,0505838 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03025357 0,05054867 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03237971 0,05406355 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03237971 0,05402606 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03237971 0,05398862 ! superoxide anion generation GO:0042554 20 15 0,000 0,03237971 0,05395123 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03237971 0,0539139 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03237971 0,05387661 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03237971 0,05383938 ! copper ion transport GO:0006825 20 15 0,000 0,03237971 0,0538022 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03237971 0,05376507 ! sulfate transport GO:0008272 23 15 0,000 0,03237971 0,05372799 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03237971 0,05369096 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03237971 0,05365398 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03237971 0,05361706 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03237971 0,05358018 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03237971 0,05354335 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03237971 0,05350658 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03237971 0,05346986 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03237971 0,05343318 ! pituitary gland development GO:0021983 29 15 0,000 0,03237971 0,05339656 ! vesicle coating GO:0006901 33 15 0,000 0,03237971 0,05335999 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03237971 0,05332346 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03237971 0,05328699 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03237971 0,05325057 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03237971 0,0532142 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03237971 0,05317787 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03237971 0,0531416 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03237971 0,05310537 ! histone deacetylation GO:0016575 20 15 0,000 0,03237971 0,0530692 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03237971 0,05303307 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03237971 0,05299699 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03237971 0,05296097 ! muscle maintenance GO:0046716 26 15 0,000 0,03237971 0,05292499 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03237971 0,05288906 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03237971 0,05285318 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03237971 0,05281734 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03237971 0,05278156 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03237971 0,05274582 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03237971 0,05271014 ! detection of bacterium GO:0016045 18 15 0,000 0,03237971 0,0526745 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03237971 0,05263891 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03237971 0,05260336 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03237971 0,05256787 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03237971 0,05253242 ! peptide hormone processing GO:0016486 23 15 0,000 0,03237971 0,05249702 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03450126 0,05589901 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03450126 0,0558614 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03450126 0,05582383 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03450126 0,05578631 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03450126 0,05574885 ! bone remodeling GO:0046849 27 16 0,000 0,03450126 0,05571143 ! filopodium assembly GO:0046847 32 16 0,000 0,03450126 0,05567407 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03450126 0,05563675 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03450126 0,05559949 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03450126 0,05556227 ! startle response GO:0001964 28 16 0,000 0,03450126 0,05552511 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03450126 0,05548799 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03450126 0,05545092 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03450126 0,05541391 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03450126 0,05537694 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03450126 0,05534002 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03450126 0,05530315 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03450126 0,05526633 ! response to osmotic stress GO:0006970 25 16 0,000 0,03450126 0,05522956 ! lysosomal transport GO:0007041 26 16 0,000 0,03450126 0,05519284 ! fructose metabolic process GO:0006000 25 16 0,000 0,03450126 0,05515617 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03450126 0,05511954 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03450126 0,05508297 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03450126 0,05504644 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03450126 0,05500996 ! axon cargo transport GO:0008088 43 16 0,000 0,03450126 0,05497353 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03450126 0,05493715 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03450126 0,05490082 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,03450126 0,05486453 ! DNA replication initiation GO:0006270 27 16 0,000 0,03450126 0,05482829 ! neuron recognition GO:0008038 35 16 0,000 0,03450126 0,0547921 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03450126 0,05475596 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03450126 0,05471986 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03450126 0,05468382 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03450126 0,05464782 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03450126 0,05461186 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03450126 0,05457596 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03450126 0,0545401 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03450126 0,05450429 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03450126 0,05446853 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03450126 0,05443281 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03450126 0,05439714 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03450126 0,05436152 ! defense response to virus GO:0051607 37 16 0,000 0,03450126 0,05432594 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03661823 0,05762162 ! metencephalon development GO:0022037 30 17 0,000 0,03661823 0,05758396 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03661823 0,05754635 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03661823 0,05750879 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03661823 0,05747127 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03661823 0,05743381 ! signal complex assembly GO:0007172 41 17 0,000 0,03661823 0,05739639 ! endothelial cell migration GO:0043542 28 17 0,000 0,03661823 0,05735903 ! inositol metabolic process GO:0006020 28 17 0,000 0,03661823 0,05732171 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03661823 0,05728444 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03661823 0,05724722 ! glial cell development GO:0021782 27 17 0,000 0,03661823 0,05721004 ! limbic system development GO:0021761 36 17 0,000 0,03661823 0,05717292 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03661823 0,05713584 ! adult walking behavior GO:0007628 33 17 0,000 0,03661823 0,05709881 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03661823 0,05706183 ! heart looping GO:0001947 30 17 0,000 0,03661823 0,0570249 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03661823 0,05698801 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03661823 0,05695117 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03661823 0,05691438 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03661823 0,05687764 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03661823 0,05684094 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03661823 0,0568043 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03661823 0,0567677 ! glycine metabolic process GO:0006544 28 17 0,000 0,03661823 0,05673114 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03661823 0,05669464 ! NAD metabolic process GO:0019674 29 17 0,000 0,03661823 0,05665818 ! membrane budding GO:0006900 37 17 0,000 0,03661823 0,05662176 ! DNA integration GO:0015074 29 17 0,000 0,03661823 0,0565854 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03661823 0,05654908 ! regulation of protein binding GO:0043393 33 17 0,000 0,03661823 0,05651281 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03661823 0,05647658 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03661823 0,0564404 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03661823 0,05640427 ! genitalia development GO:0048806 30 17 0,000 0,03661823 0,05636818 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03661823 0,05633214 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03661823 0,05629614 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03661823 0,05626019 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03661823 0,05622429 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03661823 0,05618843 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03661823 0,05615262 ! steroid catabolic process GO:0006706 31 17 0,000 0,03661823 0,05611686 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03661823 0,05608114 ! gas transport GO:0015669 25 17 0,000 0,03661823 0,05604546 ! organic cation transport GO:0015695 31 17 0,000 0,03661823 0,05600983 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03661823 0,05597425 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03661823 0,05593871 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03661823 0,05590321 ! microspike assembly GO:0030035 36 17 0,000 0,03661823 0,05586776 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03661823 0,05583236 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03873063 0,05901577 ! neuron maturation GO:0042551 42 18 0,000 0,03873063 0,05897841 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03873063 0,05894111 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03873063 0,05890385 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03873063 0,05886664 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03873063 0,05882948 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03873063 0,05879236 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03873063 0,05875529 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03873063 0,05871827 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03873063 0,05868129 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03873063 0,05864436 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03873063 0,05860748 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03873063 0,05857064 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03873063 0,05853385 ! response to retinoic acid GO:0032526 26 18 0,000 0,03873063 0,05849711 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03873063 0,05846041 ! response to fungus GO:0009620 21 18 0,000 0,03873063 0,05842376 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03873063 0,05838715 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03873063 0,05835059 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03873063 0,05831408 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03873063 0,05827761 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03873063 0,05824118 ! vitamin transport GO:0051180 27 18 0,000 0,03873063 0,05820481 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03873063 0,05816847 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03873063 0,05813219 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03873063 0,05809594 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03873063 0,05805975 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03873063 0,0580236 ! nerve development GO:0021675 28 18 0,000 0,03873063 0,05798749 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03873063 0,05795143 ! protein secretion GO:0009306 39 19 0,000 0,04083847 0,06106734 ! positive regulation of translation GO:0045727 30 19 0,000 0,04083847 0,06102941 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04083847 0,06099153 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04083847 0,06095369 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04083847 0,0609159 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04083847 0,06087816 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04083847 0,06084046 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04083847 0,06080282 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04083847 0,06076521 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04083847 0,06072766 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04083847 0,06069015 ! cerebral cortex development GO:0021987 36 19 0,000 0,04083847 0,06065269 ! pigmentation during development GO:0048066 41 19 0,000 0,04083847 0,06061527 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04083847 0,0605779 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04083847 0,06054057 ! heme metabolic process GO:0042168 36 19 0,000 0,04083847 0,06050329 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04083847 0,06046606 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04083847 0,06042887 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04083847 0,06039173 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04083847 0,06035464 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04083847 0,06031759 ! peptide cross-linking GO:0018149 37 19 0,000 0,04083847 0,06028058 ! protein export from nucleus GO:0006611 36 19 0,000 0,04083847 0,06024362 ! heart process GO:0003015 30 19 0,000 0,04083847 0,06020671 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04083847 0,06016984 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04083847 0,06013302 ! visual learning GO:0008542 36 19 0,000 0,04083847 0,06009624 ! cellular pigmentation GO:0033059 36 19 0,000 0,04083847 0,06005951 ! G1 phase GO:0051318 40 19 0,000 0,04083847 0,06002282 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04083847 0,05998617 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04083847 0,05994957 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04083847 0,05991302 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04083847 0,05987651 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04083847 0,05984004 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04083847 0,05980362 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04083847 0,05976724 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04083847 0,05973091 ! cilium assembly GO:0042384 37 19 0,000 0,04083847 0,05969462 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04083847 0,05965838 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04294175 0,06269287 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04294175 0,06265485 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04294175 0,06261688 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04294175 0,06257895 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04294175 0,06254107 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04294175 0,06250324 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,04294175 0,06246545 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04294175 0,06242771 ! response to vitamin GO:0033273 31 20 0,000 0,04294175 0,06239001 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04294175 0,06235236 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04294175 0,06231475 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04294175 0,06227719 ! response to alkaloid GO:0043279 38 20 0,000 0,04294175 0,06223967 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04294175 0,0622022 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04294175 0,06216477 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04294175 0,06212739 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04294175 0,06209006 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04294175 0,06205276 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04294175 0,06201552 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04294175 0,06197832 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04294175 0,06194116 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04294175 0,06190405 ! body fluid secretion GO:0007589 31 20 0,000 0,04294175 0,06186698 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04294175 0,06182995 ! peptide secretion GO:0002790 35 20 0,000 0,04294175 0,06179297 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04294175 0,06175604 ! sensory perception of pain GO:0019233 30 20 0,000 0,04294175 0,06171915 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04294175 0,0616823 ! diencephalon development GO:0021536 34 20 0,000 0,04294175 0,0616455 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04294175 0,06160874 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04294175 0,06157202 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04294175 0,06153535 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04294175 0,06149872 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04294175 0,06146214 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04294175 0,0614256 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04294175 0,0613891 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04294175 0,06135264 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04294175 0,06131623 ! regulation of glucose import GO:0046324 29 20 0,000 0,04294175 0,06127987 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04294175 0,06124354 ! actin filament-based movement GO:0030048 43 20 0,000 0,04294175 0,06120726 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04294175 0,06117102 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04294175 0,06113482 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04294175 0,06109867 ! negative regulation of translation GO:0017148 29 20 0,000 0,04294175 0,06106256 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04294175 0,06102649 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04294175 0,06099047 ! regulation of cell killing GO:0031341 42 21 0,000 0,04504049 0,06393359 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04504049 0,06389589 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04504049 0,06385824 ! hormone secretion GO:0046879 38 21 0,000 0,04504049 0,06382063 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04504049 0,06378306 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04504049 0,06374555 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04504049 0,06370807 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04504049 0,06367064 ! axis specification GO:0009798 38 21 0,000 0,04504049 0,06363325 ! ovarian follicle development GO:0001541 35 21 0,000 0,04504049 0,06359591 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04504049 0,06355861 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04504049 0,06352135 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04504049 0,06348414 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04504049 0,06344697 ! cell aging GO:0007569 44 21 0,000 0,04504049 0,06340985 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04504049 0,06337276 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04504049 0,06333573 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04504049 0,06329873 ! cytolysis GO:0019835 24 21 0,000 0,04504049 0,06326178 ! vasodilation GO:0042311 39 21 0,000 0,04504049 0,06322487 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04504049 0,063188 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04504049 0,06315118 ! oogenesis GO:0048477 36 21 0,000 0,04504049 0,0631144 ! DNA modification GO:0006304 34 21 0,000 0,04504049 0,06307766 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04504049 0,06304097 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04504049 0,06300432 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04504049 0,06296771 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04504049 0,06293114 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04504049 0,06289462 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04504049 0,06285814 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04504049 0,0628217 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04504049 0,0627853 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04504049 0,06274894 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04504049 0,06271263 ! collagen catabolic process GO:0030574 28 21 0,000 0,04504049 0,06267636 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04504049 0,06264013 ! gut development GO:0048565 39 21 0,000 0,04504049 0,06260394 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,0471347 0,06547696 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,0471347 0,06543918 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,0471347 0,06540144 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,0471347 0,06536374 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,0471347 0,06532609 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,0471347 0,06528848 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,0471347 0,06525092 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,0471347 0,0652134 ! keratinization GO:0031424 28 22 0,000 0,0471347 0,06517592 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,0471347 0,06513848 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,0471347 0,06510109 ! sensory perception of taste GO:0050909 28 22 0,000 0,0471347 0,06506374 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,0471347 0,06502643 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,0471347 0,06498917 ! vacuolar transport GO:0007034 36 22 0,000 0,0471347 0,06495194 ! lysosome organization GO:0007040 41 22 0,000 0,0471347 0,06491477 ! central nervous system neuron development GO:0021954 46 22 0,000 0,0471347 0,06487763 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,0471347 0,06484053 ! fucose metabolic process GO:0006004 39 22 0,000 0,0471347 0,06480348 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,0471347 0,06476647 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,0471347 0,06472951 ! ureteric bud development GO:0001657 43 22 0,000 0,0471347 0,06469258 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,0471347 0,0646557 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,0471347 0,06461886 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,0471347 0,06458206 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,0471347 0,0645453 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,0471347 0,06450859 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,0471347 0,06447191 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,0471347 0,06443528 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,0471347 0,06439869 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,0471347 0,06436214 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,0471347 0,06432564 ! protein stabilization GO:0050821 39 22 0,000 0,0471347 0,06428917 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04922439 0,06710135 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04922439 0,06706335 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04922439 0,0670254 ! gluconeogenesis GO:0006094 33 23 0,000 0,04922439 0,06698749 ! viral genome replication GO:0019079 41 23 0,000 0,04922439 0,06694962 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04922439 0,0669118 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04922439 0,06687401 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04922439 0,06683628 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04922439 0,06679858 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04922439 0,06676092 ! visual behavior GO:0007632 42 23 0,000 0,04922439 0,06672331 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04922439 0,06668574 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04922439 0,06664822 ! response to ethanol GO:0045471 46 23 0,000 0,04922439 0,06661073 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04922439 0,06657329 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,04922439 0,06653589 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04922439 0,06649853 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04922439 0,06646121 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04922439 0,06642394 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04922439 0,0663867 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,04922439 0,06634951 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04922439 0,06631236 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04922439 0,06627525 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04922439 0,06623819 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04922439 0,06620116 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04922439 0,06616418 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04922439 0,06612724 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04922439 0,06609033 ! fatty acid transport GO:0015908 44 23 0,000 0,04922439 0,06605347 ! platelet activation GO:0030168 37 23 0,000 0,04922439 0,06601666 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04922439 0,06597988 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04922439 0,06594314 ! hormone transport GO:0009914 40 23 0,000 0,04922439 0,06590644 ! cell-cell recognition GO:0009988 25 23 0,000 0,04922439 0,06586979 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04922439 0,06583317 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04922439 0,0657966 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04922439 0,06576007 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04922439 0,06572357 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04922439 0,06568712 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05130956 0,06843171 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05130956 0,0683938 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05130956 0,06835593 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05130956 0,0683181 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05130956 0,06828031 ! spinal cord development GO:0021510 47 24 0,000 0,05130956 0,06824257 ! vacuole organization GO:0007033 43 24 0,000 0,05130956 0,06820487 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05130956 0,0681672 ! digestive system process GO:0022600 39 24 0,000 0,05130956 0,06812958 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05130956 0,06809201 ! regulation of behavior GO:0050795 43 24 0,000 0,05130956 0,06805447 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05130956 0,06801697 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05130956 0,06797952 ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05130956 0,06794211 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05130956 0,06790473 ! pallium development GO:0021543 49 24 0,000 0,05130956 0,0678674 ! pentose metabolic process GO:0019321 35 24 0,000 0,05130956 0,06783011 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05130956 0,06779286 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05130956 0,06775566 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05130956 0,06771849 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05130956 0,06768136 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05130956 0,06764428 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05130956 0,06760723 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05130956 0,06757023 ! regulation of amine transport GO:0051952 40 24 0,000 0,05130956 0,06753326 ! protein tetramerization GO:0051262 52 24 0,000 0,05130956 0,06749634 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05339023 0,07019502 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,05339023 0,07015669 ! myelination GO:0042552 45 25 0,000 0,05339023 0,07011839 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05339023 0,07008014 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05339023 0,07004193 ! phototransduction GO:0007602 33 25 0,000 0,05339023 0,07000376 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05339023 0,06996563 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,05339023 0,06992754 ! sperm motility GO:0030317 31 25 0,000 0,05339023 0,0698895 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05339023 0,06985149 ! receptor metabolic process GO:0043112 46 25 0,000 0,05339023 0,06981353 ! chromosome condensation GO:0030261 45 25 0,000 0,05339023 0,06977561 ! response to starvation GO:0042594 42 25 0,000 0,05339023 0,06973773 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05339023 0,06969989 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,05339023 0,06966209 ! neural crest cell development GO:0014032 54 25 0,000 0,05339023 0,06962433 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05339023 0,06958662 ! negative regulation of cell development GO:0010721 73 25 0,000 0,05339023 0,06954894 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05339023 0,06951131 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05339023 0,06947371 ! interaction with host GO:0051701 62 25 0,000 0,05339023 0,06943616 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05339023 0,06939865 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05339023 0,06936117 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,05339023 0,06932374 ! immunoglobulin production GO:0002377 55 25 0,000 0,05339023 0,06928635 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05339023 0,069249 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05339023 0,06921169 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05339023 0,06917442 ! telomere organization GO:0032200 43 25 0,000 0,05339023 0,06913719 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05339023 0,0691 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05339023 0,06906285 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05546641 0,07170993 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05546641 0,07167141 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05546641 0,07163294 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05546641 0,07159451 ! initiation of viral infection GO:0019059 57 26 0,000 0,05546641 0,07155612 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05546641 0,07151778 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05546641 0,07147947 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05546641 0,07144121 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05546641 0,07140298 ! molting cycle process GO:0022404 50 26 0,000 0,05546641 0,0713648 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05546641 0,07132665 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05546641 0,07128855 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,05546641 0,07125049 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05546641 0,07121247 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05546641 0,07117449 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,05546641 0,07113655 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05546641 0,07109865 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05546641 0,07106079 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05546641 0,07102298 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05546641 0,0709852 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05546641 0,07094746 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05546641 0,07090976 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05546641 0,0708721 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05546641 0,07083449 ! blastocyst development GO:0001824 49 26 0,000 0,05546641 0,07079691 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05546641 0,07075937 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05546641 0,07072187 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05546641 0,07068441 ! neuron fate commitment GO:0048663 48 27 0,000 0,0575381 0,07328568 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0575381 0,07324691 ! iron ion transport GO:0006826 59 27 0,000 0,0575381 0,07320817 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0575381 0,07316948 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0575381 0,07313083 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0575381 0,07309222 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0575381 0,07305364 ! fat cell differentiation GO:0045444 50 27 0,000 0,0575381 0,07301511 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0575381 0,07297662 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0575381 0,07293818 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0575381 0,07289977 ! autophagy GO:0006914 41 27 0,000 0,0575381 0,0728614 ! male gonad development GO:0008584 44 27 0,000 0,0575381 0,07282307 ! response to toxin GO:0009636 47 27 0,000 0,0575381 0,07278478 ! primary neural tube formation GO:0014020 51 27 0,000 0,0575381 0,07274654 ! base-excision repair GO:0006284 41 27 0,000 0,0575381 0,07270833 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0575381 0,07267016 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0575381 0,07263203 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0575381 0,07259395 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0575381 0,0725559 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0575381 0,07251789 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0575381 0,07247993 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0575381 0,072442 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0575381 0,07240411 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05960531 0,07496622 ! circadian rhythm GO:0007623 50 28 0,000 0,05960531 0,07492705 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05960531 0,07488792 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05960531 0,07484884 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05960531 0,07480979 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,05960531 0,07477079 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05960531 0,07473183 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05960531 0,0746929 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05960531 0,07465402 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05960531 0,07461518 ! synaptogenesis GO:0007416 42 28 0,000 0,05960531 0,07457638 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05960531 0,07453762 ! lipid oxidation GO:0034440 43 28 0,000 0,05960531 0,0744989 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05960531 0,07446022 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05960531 0,07442157 ! translational initiation GO:0006413 65 29 0,000 0,06166806 0,07695713 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06166806 0,07691724 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06166806 0,07687738 ! regulation of pH GO:0006885 43 29 0,000 0,06166806 0,07683757 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06166806 0,0767978 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06166806 0,07675807 ! catechol metabolic process GO:0009712 54 29 0,000 0,06166806 0,07671838 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06166806 0,07667873 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06166806 0,07663913 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06166806 0,07659956 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06166806 0,07656004 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06166806 0,07652055 ! cell fate determination GO:0001709 60 29 0,000 0,06166806 0,07648111 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06166806 0,0764417 ! detection of light stimulus GO:0009583 38 29 0,000 0,06166806 0,07640234 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,06166806 0,07636302 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06166806 0,07632374 ! tissue homeostasis GO:0001894 48 29 0,000 0,06166806 0,0762845 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,06372635 0,07879013 ! zinc ion transport GO:0006829 45 30 0,000 0,06372635 0,07874967 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06372635 0,07870924 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06372635 0,07866886 ! acute-phase response GO:0006953 49 30 0,000 0,06372635 0,07862851 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06372635 0,07858821 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06372635 0,07854795 ! phospholipid transport GO:0015914 51 30 0,000 0,06372635 0,07850773 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06372635 0,07846755 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06372635 0,07842742 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06372635 0,07838732 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06372635 0,07834727 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06372635 0,07830725 ! eye morphogenesis GO:0048592 60 30 0,000 0,06372635 0,07826728 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06372635 0,07822735 ! response to heat GO:0009408 50 30 0,000 0,06372635 0,07818746 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,0657802 0,08066624 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,0657802 0,08062514 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,0657802 0,08058409 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,0657802 0,08054308 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,0657802 0,08050211 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,0657802 0,08046119 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,0657802 0,0804203 ! ovulation cycle process GO:0022602 49 31 0,000 0,0657802 0,08037946 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,0657802 0,08033866 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,0657802 0,0802979 ! peptide transport GO:0015833 55 31 0,000 0,0657802 0,08025718 ! iron ion homeostasis GO:0055072 54 31 0,000 0,0657802 0,0802165 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,0657802 0,08017586 ! mesoderm formation GO:0001707 69 31 0,000 0,0657802 0,08013527 ! natural killer cell activation GO:0030101 45 31 0,000 0,0657802 0,08009471 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,0657802 0,0800542 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,0657802 0,08001373 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,0657802 0,0799733 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,0657802 0,07993291 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06782961 0,08238164 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06782961 0,08234008 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06782961 0,08229855 ! spliceosome assembly GO:0000245 67 32 0,000 0,06782961 0,08225707 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06782961 0,08221563 ! metanephros development GO:0001656 74 32 0,000 0,06782961 0,08217424 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06782961 0,08213288 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06782961 0,08209156 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06782961 0,08205029 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,06782961 0,08200906 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06782961 0,08196787 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06782961 0,08192672 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06782961 0,08188562 ! ovulation cycle GO:0042698 51 32 0,000 0,06782961 0,08184455 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06782961 0,08180352 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06782961 0,08176254 ! hindbrain development GO:0030902 61 32 0,000 0,06782961 0,0817216 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06782961 0,0816807 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06782961 0,08163984 ! gene silencing GO:0016458 65 32 0,000 0,06782961 0,08159902 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06987459 0,08401712 ! post-embryonic development GO:0009791 69 33 0,000 0,06987459 0,08397515 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06987459 0,08393323 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,06987459 0,08389134 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06987459 0,0838495 ! formation of primary germ layer GO:0001704 72 33 0,000 0,06987459 0,0838077 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06987459 0,08376595 ! adult locomotory behavior GO:0008344 59 33 0,000 0,06987459 0,08372423 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,06987459 0,08368256 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06987459 0,08364092 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07191515 0,0860407 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07191515 0,08599794 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07191515 0,08595521 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07191515 0,08591254 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07191515 0,0858699 ! mismatch repair GO:0006298 46 34 0,000 0,07191515 0,08582731 ! spermatid development GO:0007286 63 34 0,000 0,07191515 0,08578475 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07191515 0,08574224 ! placenta development GO:0001890 53 34 0,000 0,07191515 0,08569978 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,07191515 0,08565735 ! regulation of muscle development GO:0048634 70 35 0,000 0,0739513 0,08803901 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0739513 0,08799547 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0739513 0,08795197 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0739513 0,08790851 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0739513 0,0878651 ! female gonad development GO:0008585 58 35 0,000 0,0739513 0,08782173 ! telencephalon development GO:0021537 68 35 0,000 0,0739513 0,08777841 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,0739513 0,08773512 ! cytokine production GO:0001816 59 35 0,000 0,0739513 0,08769188 ! neural tube formation GO:0001841 67 35 0,000 0,0739513 0,08764869 ! vesicle localization GO:0051648 64 35 0,000 0,0739513 0,08760553 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07598306 0,08996813 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07598306 0,08992387 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07598306 0,08987966 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07598306 0,08983549 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07598306 0,08979137 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07598306 0,08974729 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07598306 0,08970325 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07598306 0,08965926 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,07598306 0,08961531 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07598306 0,0895714 ! aerobic respiration GO:0009060 55 36 0,000 0,07598306 0,08952754 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,07598306 0,08948372 ! embryonic organ development GO:0048568 57 36 0,000 0,07598306 0,08943994 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07598306 0,0893962 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07598306 0,08935251 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07801042 0,09169178 ! meiosis I GO:0007127 65 37 0,000 0,07801042 0,09164701 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07801042 0,09160228 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07801042 0,09155759 ! organic anion transport GO:0015711 68 37 0,000 0,07801042 0,09151295 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07801042 0,09146836 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07801042 0,0914238 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07801042 0,09137929 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07801042 0,09133483 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07801042 0,0912904 ! glycogen metabolic process GO:0005977 61 37 0,000 0,07801042 0,09124602 ! pigment metabolic process GO:0042440 80 37 0,000 0,07801042 0,09120169 ! spermatid differentiation GO:0048515 66 37 0,000 0,07801042 0,09115739 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,0800334 0,0934759 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,0800334 0,09343055 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,0800334 0,09338524 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,0800334 0,09333997 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,0800334 0,09329475 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,0800334 0,09324957 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,0800334 0,09320444 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,0800334 0,09315934 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,0800334 0,0931143 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,0800334 0,09306929 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,0800334 0,09302433 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,0800334 0,09297941 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,0800334 0,09293454 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,0800334 0,09288971 ! glucan metabolic process GO:0044042 62 38 0,000 0,0800334 0,09284492 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,08205201 0,09514079 ! learning GO:0007612 77 39 0,000 0,08205201 0,09509496 ! ear morphogenesis GO:0042471 60 39 0,000 0,08205201 0,09504918 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,08205201 0,09500344 ! segmentation GO:0035282 67 39 0,000 0,08205201 0,09495774 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08205201 0,09491209 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,08205201 0,09486648 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08205201 0,09482091 ! RNA modification GO:0009451 57 39 0,000 0,08205201 0,09477539 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08205201 0,09472991 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08406626 0,09700884 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08406626 0,09696233 ! feeding behavior GO:0007631 59 40 0,000 0,08406626 0,09691587 ! negative regulation of binding GO:0051100 72 40 0,000 0,08406626 0,09686946 ! mesenchymal cell development GO:0014031 87 40 0,000 0,08406626 0,09682308 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08406626 0,09677676 ! maintenance of protein location GO:0045185 91 40 0,000 0,08406626 0,09673048 ! cytokinesis GO:0000910 72 40 0,000 0,08406626 0,09668424 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08607616 0,09894851 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08607616 0,09890126 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08607616 0,09885405 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08607616 0,09880689 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08607616 0,09875977 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08607616 0,09871269 ! T cell differentiation GO:0030217 81 41 0,000 0,08607616 0,09866567 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08607616 0,09861868 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,08607616 0,09857174 ! female gamete generation GO:0007292 61 41 0,000 0,08607616 0,09852485 ! polyol metabolic process GO:0019751 66 41 0,000 0,08607616 0,098478 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08607616 0,09843119 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08808171 0,10067676 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 0,000 0,08808171 0,10062896 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08808171 0,1005812 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08808171 0,10053349 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08808171 0,10048582 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,08808171 0,10043819 ! neuron migration GO:0001764 79 42 0,000 0,08808171 0,10039062 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,08808171 0,10034308 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,09008293 0,10257431 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09008293 0,10252579 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,09008293 0,10247731 ! glucose transport GO:0015758 65 43 0,000 0,09008293 0,10242888 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09008293 0,1023805 ! neural tube development GO:0021915 77 43 0,000 0,09008293 0,10233216 ! striated muscle contraction GO:0006941 77 43 0,000 0,09008293 0,10228387 ! phagocytosis GO:0006909 90 43 0,000 0,09008293 0,10223562 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09008293 0,10218742 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09207982 0,10440341 ! hexose transport GO:0008645 67 44 0,000 0,09207982 0,10435423 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09207982 0,1043051 ! male sex differentiation GO:0046661 76 44 0,000 0,09207982 0,10425602 ! double-strand break repair GO:0006302 81 44 0,000 0,09207982 0,10420698 ! biopolymer methylation GO:0043414 84 44 0,000 0,09207982 0,10415799 ! B cell differentiation GO:0030183 107 44 0,000 0,09207982 0,10410904 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09207982 0,10406014 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09207982 0,10401129 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09407239 0,10621219 ! glycolysis GO:0006096 65 45 0,000 0,09407239 0,10616237 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09407239 0,1061126 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,09407239 0,10606288 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09407239 0,1060132 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09407239 0,10596357 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09407239 0,10591398 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09407239 0,10586444 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09407239 0,10581495 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09606066 0,10800091 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,09606066 0,10795047 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09606066 0,10790007 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,09606066 0,10784972 ! pigmentation GO:0043473 100 46 0,000 0,09606066 0,10779942 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,09606066 0,10774916 ! positive regulation of defense response GO:0031349 76 47 0,000 0,09804463 0,10992329 ! endosome transport GO:0016197 108 47 0,000 0,09804463 0,10987209 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,09804463 0,10982094 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,09804463 0,10976984 ! JNK cascade GO:0007254 91 47 0,000 0,09804463 0,10971878 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,09804463 0,10966778 ! methylation GO:0032259 90 47 0,000 0,09804463 0,10961682 ! mitochondrial transport GO:0006839 82 48 0,000 0,10002432 0,11177822 ! Notch signaling pathway GO:0007219 96 48 0,000 0,10002432 0,11172632 ! cellular component disassembly GO:0022411 86 48 0,000 0,10002432 0,11167448 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,10002432 0,11162268 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,10002432 0,11157093 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,10002432 0,11151923 ! activation of caspase activity GO:0006919 84 48 0,000 0,10002432 0,11146758 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,10002432 0,11141597 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,10002432 0,11136442 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,10002432 0,11131291 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,10002432 0,11126144 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10199972 0,11340634 ! regulation of action potential GO:0001508 95 49 0,000 0,10199972 0,11335396 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10199972 0,11330163 ! regulation of ion transport GO:0043269 77 49 0,000 0,10199972 0,11324934 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10199972 0,1131971 ! peptide metabolic process GO:0006518 76 49 0,000 0,10199972 0,11314492 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10199972 0,11309278 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10199972 0,11304068 ! endocrine system development GO:0035270 104 49 0,000 0,10199972 0,11298864 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10199972 0,11293664 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10199972 0,11288469 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10199972 0,11283279 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10199972 0,11278094 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,10397085 0,11490761 ! neuromuscular process GO:0050905 99 50 0,000 0,10397085 0,11485485 ! regulation of ossification GO:0030278 117 50 0,000 0,10397085 0,11480214 ! inner ear development GO:0048839 79 50 0,000 0,10397085 0,11474948 ! histone modification GO:0016570 91 50 0,000 0,10397085 0,11469687 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10397085 0,1146443 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,10397085 0,11459179 ! viral infectious cycle GO:0019058 99 51 0,000 0,10593772 0,11670612 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10593772 0,11665271 ! excretion GO:0007588 83 51 0,000 0,10593772 0,11659934 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10593772 0,11654603 ! chromatin remodeling GO:0006338 109 51 0,000 0,10593772 0,11649276 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,10593772 0,11643954 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,10593772 0,11638637 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10593772 0,11633325 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,10790034 0,11843441 ! positive regulation of growth GO:0045927 90 52 0,000 0,10790034 0,1183804 ! covalent chromatin modification GO:0016569 101 52 0,000 0,10790034 0,11832645 ! amino acid activation GO:0043038 92 52 0,000 0,10790034 0,11827254 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,10790034 0,11821868 ! synapse organization GO:0050808 85 52 0,000 0,10790034 0,11816487 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10985872 0,12025481 ! RNA catabolic process GO:0006401 93 53 0,000 0,10985872 0,12020013 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10985872 0,12014549 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,10985872 0,1200909 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,10985872 0,12003637 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,10985872 0,11998188 ! cell maturation GO:0048469 100 53 0,000 0,10985872 0,11992744 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,10985872 0,11987305 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11181286 0,12195002 ! cell recognition GO:0008037 85 54 0,000 0,11181286 0,12189476 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11181286 0,12183956 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11181286 0,1217844 ! chloride transport GO:0006821 90 55 0,000 0,11376278 0,12385215 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,11376278 0,12379613 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,11376278 0,12374016 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,11376278 0,12368425 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11376278 0,12362838 ! aging GO:0007568 103 55 0,000 0,11376278 0,12357257 ! gastrulation GO:0007369 112 55 0,000 0,11376278 0,12351681 ! heart morphogenesis GO:0003007 97 55 0,000 0,11376278 0,12346109 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11376278 0,12340543 ! RNA elongation GO:0006354 79 55 0,000 0,11376278 0,12334982 ! nuclear export GO:0051168 97 55 0,000 0,11376278 0,12329425 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11376278 0,12323874 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11570848 0,1252901 ! sensory perception of smell GO:0007608 80 56 0,000 0,11570848 0,12523374 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11570848 0,12517743 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,11570848 0,12512117 ! proton transport GO:0015992 94 56 0,000 0,11570848 0,12506496 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,11764997 0,12710635 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,11764997 0,1270493 ! maintenance of location GO:0051235 118 57 0,000 0,11764997 0,1269923 ! hydrogen transport GO:0006818 97 58 0,000 0,11958727 0,12902554 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,11958727 0,12896771 ! regulation of endocytosis GO:0030100 91 58 0,000 0,11958727 0,12890993 ! adult behavior GO:0030534 99 58 0,000 0,11958727 0,1288522 ! positive regulation of secretion GO:0051047 95 59 0,000 0,12152037 0,13087646 ! regulation of cellular component size GO:0032535 109 59 0,000 0,12152037 0,13081791 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,12152037 0,1307594 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,12152037 0,13070095 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,12152037 0,13064255 ! DNA catabolic process GO:0006308 86 59 0,000 0,12152037 0,1305842 ! establishment of organelle localization GO:0051656 109 59 0,000 0,12152037 0,1305259 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1234493 0,1325386 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,1234493 0,13247949 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1234493 0,13242043 ! regulation of heart contraction GO:0008016 110 60 0,000 0,1234493 0,13236141 ! camera-type eye development GO:0043010 116 60 0,000 0,1234493 0,13230246 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,1234493 0,13224355 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12537405 0,13424565 ! mesoderm development GO:0007498 119 61 0,000 0,12537405 0,13418593 ! tRNA processing GO:0008033 89 61 0,000 0,12537405 0,13412627 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12537405 0,13406665 ! ear development GO:0043583 103 62 0,000 0,12729465 0,13605994 ! viral reproductive process GO:0022415 126 62 0,000 0,12729465 0,13599952 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12729465 0,13593916 ! gonad development GO:0008406 98 62 0,000 0,12729465 0,13587885 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,12729465 0,13581859 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,12921108 0,13780225 ! detection of external stimulus GO:0009581 91 63 0,000 0,12921108 0,13774119 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,12921108 0,13768019 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,12921108 0,13761924 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13112338 0,13959418 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13112338 0,13953244 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13112338 0,13947075 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,13112338 0,13940912 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13303153 0,14137539 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13303153 0,14131297 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,13303153 0,14125061 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,13303153 0,1411883 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,13303153 0,14112605 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13493557 0,14308284 ! actin filament organization GO:0007015 148 66 0,000 0,13493557 0,14301981 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,13493557 0,14295683 ! secondary metabolic process GO:0019748 116 66 0,000 0,13493557 0,14289391 ! developmental maturation GO:0021700 116 66 0,000 0,13493557 0,14283105 ! cell projection assembly GO:0030031 120 66 0,000 0,13493557 0,14276824 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,13683548 0,14471479 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,13683548 0,14465121 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,13683548 0,14458768 ! chromosome segregation GO:0007059 113 67 0,000 0,13683548 0,14452421 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,13683548 0,1444608 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,13683548 0,14439744 ! hexose catabolic process GO:0019320 104 67 0,000 0,13683548 0,14433413 ! adaptive immune response GO:0002250 119 67 0,000 0,13683548 0,14427088 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,13683548 0,14420769 ! amino acid transport GO:0006865 125 68 0,000 0,13873128 0,14614162 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,13873128 0,14607766 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,13873128 0,14601376 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,13873128 0,14594992 ! viral reproduction GO:0016032 134 68 0,000 0,13873128 0,14588613 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,13873128 0,14582239 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,13873128 0,14575872 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,14062298 0,14768175 ! negative regulation of cell size GO:0045792 134 69 0,000 0,14062298 0,14761732 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14062298 0,14755294 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14062298 0,14748862 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14062298 0,14742435 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14062298 0,14736014 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14062298 0,14729599 ! appendage morphogenesis GO:0035107 135 70 0,000 0,14251059 0,14920822 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,14439412 0,1511145 ! reproductive structure development GO:0048608 113 71 0,000 0,14439412 0,1510488 ! appendage development GO:0048736 136 71 0,000 0,14439412 0,15098316 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,14439412 0,15091757 ! B cell activation GO:0042113 160 71 0,000 0,14439412 0,15085204 ! acute inflammatory response GO:0002526 113 72 0,000 0,14627357 0,15274922 ! regulation of caspase activity GO:0043281 122 72 0,000 0,14627357 0,15268295 ! carbohydrate transport GO:0008643 110 72 0,000 0,14627357 0,15261674 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,14627357 0,15255059 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,14627357 0,15248449 ! regulation of blood pressure GO:0008217 125 73 0,000 0,14814895 0,15437262 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,14814895 0,15430579 ! axon guidance GO:0007411 139 73 0,000 0,14814895 0,15423902 ! fertilization GO:0009566 90 73 0,000 0,14814895 0,15417231 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,15002028 0,15605222 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,15002028 0,15598479 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15002028 0,15591741 ! meiosis GO:0007126 121 74 0,000 0,15002028 0,15585008 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,15002028 0,15578282 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15002028 0,15571561 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,15002028 0,15564847 ! eye development GO:0001654 143 74 0,000 0,15002028 0,15558138 ! organelle localization GO:0051640 136 74 0,000 0,15002028 0,15551434 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,15188756 0,1573822 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,15188756 0,15731445 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,15188756 0,15724676 ! meiotic cell cycle GO:0051321 122 75 0,000 0,15188756 0,15717913 ! rhythmic process GO:0048511 128 75 0,000 0,15188756 0,15711155 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,15188756 0,15704403 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1537508 0,15890224 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,1537508 0,15883401 ! defense response to bacterium GO:0042742 89 76 0,000 0,1537508 0,15876585 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,1537508 0,15869773 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15561 0,16054789 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15561 0,16047907 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15561 0,16041031 ! blood coagulation GO:0007596 146 78 0,000 0,15746519 0,16225321 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,15746519 0,16218375 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,15931636 0,16402018 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,15931636 0,16395003 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,15931636 0,16387993 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,15931636 0,1638099 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,16116352 0,16563838 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,16116352 0,16556765 ! protein import into nucleus GO:0006606 158 80 0,000 0,16116352 0,16549699 ! inorganic anion transport GO:0015698 138 80 0,000 0,16116352 0,16542638 ! T cell activation GO:0042110 168 81 0,000 0,16300669 0,16724695 ! digestion GO:0007586 112 81 0,000 0,16300669 0,16717566 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,16300669 0,16710443 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16300669 0,16703326 ! nuclear import GO:0051170 161 81 0,000 0,16300669 0,16696215 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,16300669 0,16689111 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,16484587 0,16870232 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,16484587 0,1686306 ! response to drug GO:0042493 143 82 0,000 0,16484587 0,16855893 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16484587 0,16848732 ! regulation of lyase activity GO:0051339 160 83 0,000 0,16668107 0,17029072 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,16851229 0,17208853 ! hemostasis GO:0007599 158 84 0,000 0,16851229 0,17201552 ! negative regulation of growth GO:0045926 155 84 0,000 0,16851229 0,17194257 ! regulation of ligase activity GO:0051340 142 84 0,000 0,16851229 0,17186968 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,16851229 0,17179685 ! response to unfolded protein GO:0006986 131 85 0,000 0,17033956 0,17358618 ! nucleosome assembly GO:0006334 122 85 0,000 0,17033956 0,17351269 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17033956 0,17343926 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,17216286 0,1752216 ! chromatin assembly GO:0031497 124 86 0,000 0,17216286 0,17514751 ! mitochondrion organization GO:0007005 148 86 0,000 0,17216286 0,17507348 ! alcohol catabolic process GO:0046164 130 86 0,000 0,17216286 0,17499951 ! amine transport GO:0015837 155 86 0,000 0,17216286 0,17492561 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,17398223 0,17669955 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,17398223 0,17662499 ! protein localization in nucleus GO:0034504 176 87 0,000 0,17398223 0,1765505 ! cellular respiration GO:0045333 135 88 0,000 0,17579765 0,17831751 ! regulation of neurological system process GO:0031644 148 88 0,000 0,17579765 0,17824237 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,17579765 0,17816729 ! cellular defense response GO:0006968 114 89 0,000 0,17760914 0,17992741 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,17760914 0,17985168 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,17760914 0,17977602 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,17941672 0,18152928 ! sex differentiation GO:0007548 145 90 0,000 0,17941672 0,18145297 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,17941672 0,18137673 ! sterol metabolic process GO:0016125 152 91 0,000 0,18122038 0,18312315 ! response to protein stimulus GO:0051789 149 91 0,000 0,18122038 0,18304627 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,18122038 0,18296946 ! regulation of defense response GO:0031347 149 92 0,000 0,18302013 0,18470908 ! nucleosome organization GO:0034728 138 92 0,000 0,18302013 0,18463163 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,18302013 0,18455425 ! vitamin metabolic process GO:0006766 139 92 0,000 0,18302013 0,18447693 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,18481599 0,18620908 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,18481599 0,18613113 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,18481599 0,18605325 ! female pregnancy GO:0007565 164 94 0,000 0,18660796 0,18777865 ! transcription initiation GO:0006352 153 94 0,000 0,18660796 0,18770015 ! forebrain development GO:0030900 188 95 0,000 0,18839605 0,18941952 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,18839605 0,18934039 ! leukocyte differentiation GO:0002521 202 96 0,000 0,19018027 0,19105375 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,19018027 0,19097401 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,19018027 0,19089434 ! detection of stimulus GO:0051606 151 96 0,000 0,19018027 0,19081474 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,19196063 0,19252075 ! protein ubiquitination GO:0016567 217 97 0,000 0,19196063 0,19244053 ! hormone metabolic process GO:0042445 157 97 0,000 0,19196063 0,19236038 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,19373713 0,19405976 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,19373713 0,193979 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,19550979 0,19567244 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,19550979 0,19559108 ! cell cycle arrest GO:0007050 213 100 0,000 0,19727861 0,19727861