pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1181-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 13 6 2,000 2,355E-07 5,753E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 2,355E-07 2,877E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 17 8 2,000 6,572E-07 5,352E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 6,572E-07 4,014E-04 ! macrophage differentiation GO:0030225 15 9 2,000 9,841E-07 4,809E-04 ! tissue remodeling GO:0048771 78 37 3,000 1,639E-06 6,675E-04 ! nucleus localization GO:0051647 22 11 2,000 1,927E-06 6,724E-04 ! regulation of cell projection assembly GO:0060491 33 12 2,000 2,565E-06 7,832E-04 ! gland morphogenesis GO:0022612 31 13 2,000 3,329E-06 9,035E-04 ! filopodium assembly GO:0046847 42 17 2,000 7,861E-06 1,921E-03 ! microspike assembly GO:0030035 46 18 2,000 9,418E-06 2,092E-03 ! regulation of protein complex assembly GO:0043254 132 63 3,000 1,413E-05 2,876E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,527E-05 2,87E-03 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 1,7E-05 2,967E-03 ! lung development GO:0030324 165 69 3,000 2,029E-05 3,304E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 2,313E-05 3,531E-03 ! respiratory tube development GO:0030323 171 72 3,000 2,402E-05 3,452E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 2,624E-05 3,561E-03 ! vasculogenesis GO:0001570 49 25 2,000 2,624E-05 3,374E-03 ! respiratory system development GO:0060541 175 74 3,000 2,677E-05 3,27E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 3,326E-05 3,869E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 3,326E-05 3,693E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 3,326E-05 3,532E-03 ! response to hypoxia GO:0001666 178 81 3,000 3,823E-05 3,892E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 4,141E-05 4,046E-03 ! response to oxygen levels GO:0070482 183 83 3,000 4,208E-05 3,954E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 4,593E-05 4,156E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,234E-05 4,567E-03 ! parathyroid gland development GO:0060017 14 5 1,000 5,234E-05 4,409E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 5,234E-05 4,262E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 5,234E-05 4,125E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 5,234E-05 3,996E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 5,234E-05 3,875E-03 GO:0051930|regulation of sensory perception of pain, ! protein insertion into membrane GO:0051205 17 5 1,000 5,234E-05 3,761E-03 ! gland development GO:0048732 220 91 3,000 6,036E-05 4,213E-03 ! neurofilament cytoskeleton organization GO:0060052 12 6 1,000 7,839E-05 5,32E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 8,058E-05 5,321E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 9,418E-05 6,055E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,096E-04 6,864E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 1,096E-04 6,693E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,096E-04 6,529E-03 GO:0043489|RNA stabilization, ! vesicle fusion GO:0006906 20 7 1,000 1,096E-04 6,374E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 1,096E-04 6,226E-03 ! mammary gland development GO:0030879 93 40 2,000 1,099E-04 6,104E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,184E-04 6,428E-03 ! epithelial cell differentiation GO:0030855 83 43 2,000 1,366E-04 7,256E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,459E-04 7,583E-03 ! male meiosis GO:0007140 9 8 1,000 1,459E-04 7,425E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,459E-04 7,274E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,459E-04 7,128E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,459E-04 6,988E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,459E-04 6,854E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,459E-04 6,725E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,459E-04 6,6E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 1,459E-04 6,48E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 1,459E-04 6,364E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,566E-04 6,711E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 1,566E-04 6,595E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,672E-04 6,924E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 1,783E-04 7,261E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,873E-04 7,501E-03 ! induction of positive chemotaxis GO:0050930 17 9 1,000 1,873E-04 7,38E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,873E-04 7,263E-03 ! S phase GO:0051320 10 9 1,000 1,873E-04 7,149E-03 GO:0000084|S phase of mitotic cell cycle, ! regulation of cell projection organization GO:0031344 135 51 2,000 2,275E-04 8,551E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,338E-04 8,653E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,338E-04 8,524E-03 ! lung alveolus development GO:0048286 26 10 1,000 2,338E-04 8,398E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 2,338E-04 8,277E-03 ! induction of an organ GO:0001759 17 10 1,000 2,338E-04 8,158E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,338E-04 8,043E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,338E-04 7,932E-03 ! response to UV GO:0009411 120 55 2,000 2,847E-04 9,528E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,853E-04 9,418E-03 ! blood vessel remodeling GO:0001974 30 11 1,000 2,853E-04 9,293E-03 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 2,853E-04 9,17E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,853E-04 9,051E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,853E-04 8,935E-03 ! substrate-bound cell migration GO:0006929 14 11 1,000 2,853E-04 8,822E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 2,853E-04 8,712E-03 ! thymus development GO:0048538 29 11 1,000 2,853E-04 8,604E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 3,165E-04 9,429E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 3,332E-04 9,807E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 3,418E-04 9,941E-03 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 3,418E-04 9,824E-03 GO:0050927|positive regulation of positive chemotaxis, ! entry into host cell GO:0030260 34 12 1,000 3,418E-04 9,71E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 3,418E-04 9,599E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,418E-04 9,49E-03 ! regulation of leukocyte migration GO:0002685 29 12 1,000 3,418E-04 9,383E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 3,418E-04 9,279E-03 ! developmental induction GO:0031128 22 12 1,000 3,418E-04 9,177E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 3,418E-04 9,077E-03 ! establishment of organelle localization GO:0051656 122 59 2,000 3,505E-04 9,206E-03 ! organelle fusion GO:0048284 36 13 1,000 4,034E-04 0,01048337 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 4,034E-04 0,01037301 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 4,034E-04 0,01026496 ! regulation of mRNA stability GO:0043488 32 13 1,000 4,034E-04 0,01015914 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 4,455E-04 0,0111046 ! positive regulation of cell motion GO:0051272 157 65 2,000 4,662E-04 0,01150522 ! lipid localization GO:0010876 32 14 1,000 4,699E-04 0,01147954 GO:0019915|lipid storage, ! regulation of cellular pH GO:0030641 27 14 1,000 4,699E-04 0,01136588 ! regulation of RNA stability GO:0043487 33 14 1,000 4,699E-04 0,01125445 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 4,699E-04 0,01114518 ! myeloid cell differentiation GO:0030099 126 67 2,000 5,096E-04 0,01197165 ! cell projection assembly GO:0030031 138 68 2,000 5,323E-04 0,01238435 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 5,414E-04 0,01247715 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 5,414E-04 0,01236055 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 5,414E-04 0,0122461 ! regulation of vasodilation GO:0042312 27 15 1,000 5,414E-04 0,01213375 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 5,414E-04 0,01202344 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 5,556E-04 0,01222712 ! negative regulation of kinase activity GO:0033673 145 70 2,000 5,795E-04 0,01263957 ! startle response GO:0001964 28 16 1,000 6,178E-04 0,01335624 ! intermediate filament-based process GO:0045103 36 16 1,000 6,178E-04 0,01323908 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 6,178E-04 0,01312396 ! negative regulation of transferase activity GO:0051348 155 74 2,000 6,817E-04 0,01435631 ! organelle localization GO:0051640 155 74 2,000 6,817E-04 0,0142336 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 6,991E-04 0,01447397 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 6,991E-04 0,01435234 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 6,991E-04 0,01423274 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 7,853E-04 0,01585573 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 7,853E-04 0,01572576 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 8,764E-04 0,01740687 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 8,764E-04 0,01726649 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 9,723E-04 0,01900304 ! protein amino acid acetylation GO:0006473 41 20 1,000 9,723E-04 0,01885222 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 9,723E-04 0,01870378 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 1,02E-03 0,01946545 ! lipid phosphorylation GO:0046834 43 21 1,000 1,073E-03 0,02032164 ! regulation of vasoconstriction GO:0019229 40 21 1,000 1,073E-03 0,02016532 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 1,073E-03 0,02001139 ! inactivation of MAPK activity GO:0000188 45 22 1,000 1,179E-03 0,02181309 ! positive regulation of locomotion GO:0040017 44 22 1,000 1,179E-03 0,02164908 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,179E-03 0,02148752 ! regulation of chemotaxis GO:0050920 45 23 1,000 1,289E-03 0,02332469 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 1,404E-03 0,02522025 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,404E-03 0,02503616 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,404E-03 0,02485474 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,404E-03 0,02467593 ! membrane depolarization GO:0051899 45 24 1,000 1,404E-03 0,02449967 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,404E-03 0,02432592 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 1,406E-03 0,0241855 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,524E-03 0,02603243 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,524E-03 0,02585165 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,524E-03 0,02567336 ! regulation of behavior GO:0050795 48 25 1,000 1,524E-03 0,02549751 ! interaction with host GO:0051701 66 25 1,000 1,524E-03 0,02532406 ! leukocyte differentiation GO:0002521 232 98 2,000 1,537E-03 0,02537237 ! skeletal muscle tissue development GO:0007519 223 100 2,000 1,629E-03 0,02670497 GO:0060538|skeletal muscle organ development, ! initiation of viral infection GO:0019059 60 26 1,000 1,648E-03 0,02684552 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 1,648E-03 0,02666774 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,648E-03 0,02649229 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,648E-03 0,02631914 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 1,648E-03 0,02614824 ! regulation of blood coagulation GO:0030193 46 26 1,000 1,648E-03 0,02597954 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 1,911E-03 0,02993284 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,911E-03 0,02974219 ! protein amino acid acylation GO:0043543 59 28 1,000 1,911E-03 0,02955395 ! vesicle docking GO:0048278 55 28 1,000 1,911E-03 0,02936807 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,911E-03 0,02918452 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 2,05E-03 0,0311051 ! somitogenesis GO:0001756 52 29 1,000 2,05E-03 0,03091309 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 2,193E-03 0,0328688 ! regulation of B cell activation GO:0050864 55 30 1,000 2,193E-03 0,03266838 ! regulation of coagulation GO:0050818 52 30 1,000 2,193E-03 0,03247039 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 2,341E-03 0,03444911 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 2,341E-03 0,03424283 ! regulation of pH GO:0006885 56 33 1,000 2,65E-03 0,0385354 ! cholesterol homeostasis GO:0042632 60 33 1,000 2,65E-03 0,03830738 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 2,65E-03 0,03808204 ! cholesterol transport GO:0030301 62 34 1,000 2,811E-03 0,0401655 ! cell fate specification GO:0001708 56 34 1,000 2,811E-03 0,03993198 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 2,811E-03 0,03970116 ! adult locomotory behavior GO:0008344 62 34 1,000 2,811E-03 0,03947299 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 2,811E-03 0,03924743 ! membrane docking GO:0022406 69 35 1,000 2,977E-03 0,04132778 ! sterol transport GO:0015918 63 35 1,000 2,977E-03 0,04109429 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,977E-03 0,04086342 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 3,323E-03 0,0453484 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 3,323E-03 0,04509646 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 3,323E-03 0,04484731 ! regulation of microtubule-based process GO:0032886 86 37 1,000 3,323E-03 0,0446009 ! neutral lipid metabolic process GO:0006638 54 38 1,000 3,502E-03 0,04675162 GO:0006639|acylglycerol metabolic process, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 3,686E-03 0,04893781 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! lipid homeostasis GO:0055088 75 40 1,000 3,874E-03 0,05115863 ! mismatch repair GO:0006298 58 40 1,000 3,874E-03 0,05088359 ! glycerol ether metabolic process GO:0006662 57 40 1,000 3,874E-03 0,05061148 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 4,067E-03 0,05284502 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 1,000 4,067E-03 0,05256541 GO:0015986|ATP synthesis coupled proton transport, ! organic ether metabolic process GO:0018904 59 42 1,000 4,264E-03 0,05482135 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 4,465E-03 0,05710929 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 4,465E-03 0,05681184 ! ion transmembrane transport GO:0034220 79 43 1,000 4,465E-03 0,05651748 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 4,671E-03 0,05881581 ! cell growth GO:0016049 90 46 1,000 5,095E-03 0,06382861 ! positive regulation of cell cycle GO:0045787 96 48 1,000 5,536E-03 0,06900302 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 5,536E-03 0,06865275 ! positive regulation of DNA binding GO:0043388 83 48 1,000 5,536E-03 0,06830602 ! vascular process in circulatory system GO:0003018 85 48 1,000 5,536E-03 0,06796278 ! JNK cascade GO:0007254 106 49 1,000 5,763E-03 0,07039556 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 5,763E-03 0,07004534 ! protein homooligomerization GO:0051260 84 49 1,000 5,763E-03 0,06969858 ! endocrine system development GO:0035270 109 50 1,000 5,994E-03 0,07213749 ! viral infectious cycle GO:0019058 104 51 1,000 6,23E-03 0,07460262 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 6,23E-03 0,0742387 ! positive regulation of binding GO:0051099 88 52 1,000 6,469E-03 0,07671911 ! histone modification GO:0016570 104 52 1,000 6,469E-03 0,07634849 ! vesicle organization GO:0016050 127 53 1,000 6,713E-03 0,0788436 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 6,713E-03 0,07846636 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! activation of phospholipase C activity GO:0007202 110 54 1,000 6,961E-03 0,08097563 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 6,961E-03 0,08059186 ! regulation of muscle contraction GO:0006937 94 54 1,000 6,961E-03 0,08021171 ! membrane fusion GO:0006944 122 54 1,000 6,961E-03 0,07983513 ! covalent chromatin modification GO:0016569 115 54 1,000 6,961E-03 0,07946207 ! regulation of cell shape GO:0008360 142 54 1,000 6,961E-03 0,07909248 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 7,213E-03 0,0815756 ! regulation of protein polymerization GO:0032271 117 55 1,000 7,213E-03 0,08119967 ! regulation of bone remodeling GO:0046850 143 57 1,000 7,729E-03 0,08661066 ! regulation of phospholipase activity GO:0010517 113 57 1,000 7,729E-03 0,08621518 ! regulation of tissue remodeling GO:0034103 146 58 1,000 7,993E-03 0,08875627 ! positive regulation of organelle organization GO:0010638 108 58 1,000 7,993E-03 0,08835466 ! positive regulation of lipase activity GO:0060193 115 58 1,000 7,993E-03 0,08795666 ! lipid modification GO:0030258 112 60 1,000 8,533E-03 0,09348143 ! adult behavior GO:0030534 104 60 1,000 8,533E-03 0,0930641 ! proton transport GO:0015992 117 61 1,000 8,809E-03 0,09564885 ! viral reproductive process GO:0022415 132 62 1,000 9,089E-03 0,09825362 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 9,089E-03 0,09782079 ! regulation of homeostatic process GO:0032844 148 62 1,000 9,089E-03 0,09739175 ! hydrogen transport GO:0006818 121 64 1,000 9,661E-03 0,10306935 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 9,661E-03 0,10262122 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,01024915 0,1083925 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,01054882 0,11108094 ! extracellular matrix organization GO:0030198 146 68 1,000 0,01085236 0,11378672 ! viral reproduction GO:0016032 142 68 1,000 0,01085236 0,11330045 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01085236 0,11281832 ! adaptive immune response GO:0002250 126 68 1,000 0,01085236 0,11234028 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 144 69 1,000 0,01115972 0,11503462 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,01115972 0,11455128 ! germ cell development GO:0007281 133 70 1,000 0,01147091 0,11725283 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01148254 0,11688271 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01148254 0,11639772 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01148254 0,11591674 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01148254 0,11543971 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01148254 0,1149666 ! neuron fate determination GO:0048664 7 5 0,000 0,01148254 0,11449735 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01148254 0,11403191 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01148254 0,11357025 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01148254 0,1131123 ! polyol transport GO:0015791 12 5 0,000 0,01148254 0,11265803 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01148254 0,1122074 ! response to superoxide GO:0000303 10 5 0,000 0,01148254 0,11176036 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01148254 0,11131687 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01148254 0,11087688 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01148254 0,11044036 ! female meiosis GO:0007143 10 5 0,000 0,01148254 0,11000726 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01148254 0,10957754 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01148254 0,10915117 ! hypothalamus development GO:0021854 9 5 0,000 0,01148254 0,1087281 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01148254 0,1083083 ! cobalt ion transport GO:0006824 11 5 0,000 0,01148254 0,10789173 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01148254 0,10747835 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01148254 0,10706813 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01148254 0,10666103 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01148254 0,10625701 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01148254 0,10585604 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01148254 0,10545808 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01148254 0,10506311 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01148254 0,10467108 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01148254 0,10428197 ! transposition GO:0032196 9 5 0,000 0,01148254 0,10389574 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01148254 0,10351236 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01148254 0,1031318 ! negative chemotaxis GO:0050919 16 5 0,000 0,01148254 0,10275403 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01148254 0,10237902 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01148254 0,10200673 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01148254 0,10163714 ! behavioral response to pain GO:0048266 10 5 0,000 0,01148254 0,10127022 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01148254 0,10090594 ! Notch receptor processing GO:0007220 11 5 0,000 0,01148254 0,10054427 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01148254 0,10018518 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01148254 0,09982865 ! micturition GO:0060073 9 5 0,000 0,01148254 0,09947465 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01148254 0,09912315 ! copulation GO:0007620 9 5 0,000 0,01148254 0,09877412 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01148254 0,09842755 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01148254 0,09808339 ! bioluminescence GO:0008218 9 5 0,000 0,01148254 0,09774164 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01148254 0,09740226 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01148254 0,09706523 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01148254 0,09673052 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01148254 0,09639811 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01148254 0,09606798 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01148254 0,0957401 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01148254 0,09541446 ! grooming behavior GO:0007625 6 5 0,000 0,01148254 0,09509102 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01148254 0,09476977 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01148254 0,09445068 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01148254 0,09413373 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01148254 0,0938189 ! response to protozoan GO:0001562 13 5 0,000 0,01148254 0,09350617 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01148254 0,09319552 ! lymph vessel development GO:0001945 10 5 0,000 0,01148254 0,09288692 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01148254 0,09258036 ! endochondral ossification GO:0001958 17 5 0,000 0,01148254 0,09227582 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01148254 0,09197328 ! single strand break repair GO:0000012 8 5 0,000 0,01148254 0,09167271 ! anagen GO:0042640 7 5 0,000 0,01148254 0,09137411 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01148254 0,09107744 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01148254 0,09078269 ! cytokine secretion GO:0050663 15 5 0,000 0,01148254 0,09048984 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01148254 0,09019888 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01148254 0,08990978 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01148254 0,08962253 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01148254 0,0893371 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01148254 0,08905349 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01148254 0,08877168 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01148254 0,08849164 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01148254 0,08821337 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01148254 0,08793684 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01148254 0,08766203 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01148254 0,08738894 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01148254 0,08711755 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01148254 0,08684783 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01148254 0,08657979 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01148254 0,08631339 ! microvillus organization GO:0032528 8 5 0,000 0,01148254 0,08604862 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01148254 0,08578548 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01148254 0,08552393 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01148254 0,08526398 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01148254 0,08500561 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01148254 0,08474879 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01148254 0,08449353 ! polyol catabolic process GO:0046174 9 5 0,000 0,01148254 0,08423979 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01148254 0,08398758 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01148254 0,08373687 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01148254 0,08348765 ! muscle cell migration GO:0014812 8 5 0,000 0,01148254 0,08323991 ! mitochondrial fission GO:0000266 8 5 0,000 0,01148254 0,08299364 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01148254 0,08274882 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01148254 0,08250544 ! mRNA transcription GO:0009299 10 5 0,000 0,01148254 0,08226349 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01148254 0,08202295 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01148254 0,08178382 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01148254 0,08154608 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01148254 0,08130971 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01148254 0,08107471 ! monocyte activation GO:0042117 10 5 0,000 0,01148254 0,08084107 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01148254 0,08060877 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01148254 0,0803778 ! response to food GO:0032094 6 5 0,000 0,01148254 0,08014814 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01148254 0,0799198 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01148254 0,07969276 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01148254 0,079467 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01148254 0,07924252 ! forebrain neuron development GO:0021884 13 5 0,000 0,01148254 0,0790193 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01148254 0,07879733 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01148254 0,07857661 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01148254 0,07835712 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01148254 0,07813886 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01148254 0,07792181 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01148254 0,07770596 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01148254 0,0774913 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01148254 0,07727783 ! lipid glycosylation GO:0030259 7 5 0,000 0,01148254 0,07706552 ! nucleobase transport GO:0015851 6 5 0,000 0,01148254 0,07685439 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01148254 0,0766444 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01148254 0,07643556 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01148254 0,07622785 ! basic amino acid transport GO:0015802 12 5 0,000 0,01148254 0,07602128 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01148254 0,07581581 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01148254 0,07561146 ! actin nucleation GO:0045010 11 5 0,000 0,01148254 0,0754082 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01148254 0,07520603 ! depurination GO:0045007 5 5 0,000 0,01148254 0,07500495 ! depyrimidination GO:0045008 10 5 0,000 0,01148254 0,07480493 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01148254 0,07460599 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01148254 0,07440809 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01148254 0,07421124 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01148254 0,07401544 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01148254 0,07382066 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01148254 0,0736269 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01148254 0,07343416 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01148254 0,07324243 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01148254 0,07305169 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01148254 0,07286195 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01148254 0,07267319 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01148254 0,0724854 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01148254 0,07229858 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01148254 0,07211273 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01148254 0,07192782 ! response to arsenic GO:0046685 11 5 0,000 0,01148254 0,07174386 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01148254 0,07156084 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01148254 0,07137875 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01148254 0,07119759 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01148254 0,07101734 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01148254 0,07083801 ! response to mercury ion GO:0046689 8 5 0,000 0,01148254 0,07065957 ! response to cadmium ion GO:0046686 7 5 0,000 0,01148254 0,07048204 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01148254 0,07030539 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01148254 0,07012963 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01148254 0,06995474 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01148254 0,06978072 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01148254 0,06960757 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01148254 0,06943527 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01148254 0,06926383 ! decidualization GO:0046697 11 5 0,000 0,01148254 0,06909323 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01148254 0,06892347 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01148254 0,06875454 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01148254 0,06858643 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01148254 0,06841915 ! embryonic cleavage GO:0040016 6 5 0,000 0,01148254 0,06825268 ! peroxisome fission GO:0016559 5 5 0,000 0,01148254 0,06808702 ! histone demethylation GO:0016577 13 5 0,000 0,01148254 0,06792216 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01148254 0,06775809 ! mitotic recombination GO:0006312 9 5 0,000 0,01148254 0,06759482 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01148254 0,06743233 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01148254 0,06727062 ! metaphase plate congression GO:0051310 7 5 0,000 0,01148254 0,06710969 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01148254 0,06694952 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01148254 0,06679012 ! enteric nervous system development GO:0048484 8 5 0,000 0,01148254 0,06663147 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01148254 0,06647358 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01148254 0,06631643 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01148254 0,06616002 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01148254 0,06600435 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01148254 0,06584941 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01148254 0,0656952 ! B cell homeostasis GO:0001782 13 5 0,000 0,01148254 0,06554171 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01148254 0,06538893 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01148254 0,06523686 ! metaphase GO:0051323 11 5 0,000 0,01148254 0,0650855 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01148254 0,06493484 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01148254 0,06478487 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01148254 0,0646356 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01148254 0,06448701 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01148254 0,06433911 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01148254 0,06419188 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01148254 0,06404532 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01148254 0,06389943 ! response to redox state GO:0051775 6 5 0,000 0,01148254 0,06375421 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01148254 0,06360964 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01148254 0,06346573 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01148254 0,06332246 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01148254 0,06317984 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01148254 0,06303787 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01148254 0,06289653 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01148254 0,06275582 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01148254 0,06261574 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01148254 0,06247628 ! striatum development GO:0021756 14 5 0,000 0,01148254 0,06233745 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01148254 0,06219923 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01148254 0,06206162 ! glial cell migration GO:0008347 10 5 0,000 0,01148254 0,06192461 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01148254 0,06178822 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01148254 0,06165242 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01148254 0,06151722 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01148254 0,06138261 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01148254 0,06124858 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01148254 0,06111514 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01148254 0,06098228 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01148254 0,06085 ! neuroprotection GO:0043526 8 5 0,000 0,01148254 0,06071829 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01148254 0,06058715 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01148254 0,06045657 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01148254 0,06032656 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01148254 0,0601971 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01148254 0,0600682 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01148254 0,05993985 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01148254 0,05981205 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01148254 0,05968479 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01148254 0,05955807 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01148254 0,05943189 ! spindle assembly GO:0051225 6 5 0,000 0,01148254 0,05930624 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01148254 0,05918112 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01148254 0,05905653 ! protein palmitoylation GO:0018345 12 5 0,000 0,01148254 0,05893246 ! drug metabolic process GO:0017144 7 5 0,000 0,01148254 0,05880891 ! stem cell division GO:0017145 11 5 0,000 0,01148254 0,05868588 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01148254 0,05856336 ! organ regeneration GO:0031100 7 5 0,000 0,01148254 0,05844136 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01148254 0,05831986 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01148254 0,05819886 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,01178589 0,05961269 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,01210465 0,06109848 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01308342 0,06590269 GO:0090046|regulation of transcription regulator activity, ! axon guidance GO:0007411 162 75 1,000 0,01308342 0,06576709 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01375449 0,06899842 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01376337 0,06890147 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01376337 0,06876057 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01376337 0,06862024 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01376337 0,06848049 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01376337 0,0683413 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01376337 0,06820268 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01376337 0,06806461 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01376337 0,06792711 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01376337 0,06779016 ! response to oxygen radical GO:0000305 11 6 0,000 0,01376337 0,06765376 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01376337 0,06751791 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01376337 0,0673826 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01376337 0,06724784 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01376337 0,06711361 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01376337 0,06697992 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01376337 0,06684676 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01376337 0,06671413 ! forebrain regionalization GO:0021871 9 6 0,000 0,01376337 0,06658202 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01376337 0,06645043 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01376337 0,06631937 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01376337 0,06618882 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01376337 0,06605878 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01376337 0,06592925 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01376337 0,06580023 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01376337 0,06567172 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01376337 0,0655437 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01376337 0,06541619 ! malate metabolic process GO:0006108 13 6 0,000 0,01376337 0,06528916 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01376337 0,06516263 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01376337 0,06503659 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01376337 0,06491104 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01376337 0,06478597 ! protein refolding GO:0042026 15 6 0,000 0,01376337 0,06466138 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01376337 0,06453727 ! opsonization GO:0008228 8 6 0,000 0,01376337 0,06441364 ! mating behavior GO:0007617 7 6 0,000 0,01376337 0,06429048 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01376337 0,06416778 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01376337 0,06404556 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01376337 0,0639238 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01376337 0,0638025 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01376337 0,06368167 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01376337 0,06356128 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01376337 0,06344136 ! toxin metabolic process GO:0009404 11 6 0,000 0,01376337 0,06332188 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01376337 0,06320286 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01376337 0,06308428 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01376337 0,06296614 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01376337 0,06284845 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01376337 0,06273119 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01376337 0,06261437 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01376337 0,06249799 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01376337 0,06238204 ! thymic T cell selection GO:0045061 16 6 0,000 0,01376337 0,06226652 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01376337 0,06215142 ! protein lipoylation GO:0009249 10 6 0,000 0,01376337 0,06203675 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01376337 0,0619225 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01376337 0,06180868 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01376337 0,06169526 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01376337 0,06158227 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01376337 0,06146969 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01376337 0,06135752 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01376337 0,06124575 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01376337 0,0611344 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01376337 0,06102345 ! hyperosmotic response GO:0006972 10 6 0,000 0,01376337 0,0609129 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01376337 0,06080275 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01376337 0,06069299 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01376337 0,06058364 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01376337 0,06047467 ! urea metabolic process GO:0019627 7 6 0,000 0,01376337 0,0603661 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01376337 0,06025792 ! neutrophil activation GO:0042119 7 6 0,000 0,01376337 0,06015012 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01376337 0,06004271 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01376337 0,05993568 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01376337 0,05982904 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01376337 0,05972277 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01376337 0,05961688 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01376337 0,05951136 ! neuron apoptosis GO:0051402 15 6 0,000 0,01376337 0,05940622 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01376337 0,05930144 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01376337 0,05919704 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01376337 0,059093 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01376337 0,05898933 ! carnitine transport GO:0015879 10 6 0,000 0,01376337 0,05888602 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01376337 0,05878308 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01376337 0,05868049 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01376337 0,05857826 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01376337 0,05847638 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01376337 0,05837486 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01376337 0,05827369 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01376337 0,05817287 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01376337 0,0580724 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01376337 0,05797227 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01376337 0,05787249 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01376337 0,05777306 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01376337 0,05767396 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01376337 0,0575752 ! response to UV-C GO:0010225 14 6 0,000 0,01376337 0,05747678 ! astrocyte development GO:0014002 16 6 0,000 0,01376337 0,0573787 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01376337 0,05728095 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01376337 0,05718354 ! interaction with symbiont GO:0051702 14 6 0,000 0,01376337 0,05708645 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01376337 0,05698969 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01376337 0,05689326 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01376337 0,05679716 ! response to copper ion GO:0046688 10 6 0,000 0,01376337 0,05670138 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01376337 0,05660592 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01376337 0,05651079 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01376337 0,05641597 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01376337 0,05632147 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01376337 0,05622729 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01376337 0,05613342 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01376337 0,05603987 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01376337 0,05594662 ! hair follicle maturation GO:0048820 8 6 0,000 0,01376337 0,05585369 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01376337 0,05576106 ! Schwann cell development GO:0014044 15 6 0,000 0,01376337 0,05566874 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01376337 0,05557673 ! response to pheromone GO:0019236 6 6 0,000 0,01376337 0,05548502 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01376337 0,05539361 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01376337 0,0553025 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01376337 0,05521169 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01376337 0,05512118 ! subpallium development GO:0021544 15 6 0,000 0,01376337 0,05503096 ! neural tube patterning GO:0021532 8 6 0,000 0,01376337 0,05494104 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01376337 0,05485142 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01376337 0,05476208 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01376337 0,05467304 ! G2 phase GO:0051319 16 6 0,000 0,01376337 0,05458428 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01376337 0,05449582 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01376337 0,05440764 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01376337 0,05431974 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01376337 0,05423213 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01376337 0,0541448 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01376337 0,05405775 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01376337 0,05397098 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01376337 0,05388449 ! receptor internalization GO:0031623 11 6 0,000 0,01376337 0,05379827 ! plasminogen activation GO:0031639 9 6 0,000 0,01376337 0,05371233 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01376337 0,05362667 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01376337 0,05354127 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01376337 0,05345615 ! protein deubiquitination GO:0016579 16 6 0,000 0,01376337 0,0533713 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01376337 0,05328672 ! protein destabilization GO:0031648 9 6 0,000 0,01376337 0,0532024 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01376337 0,05311836 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01376337 0,05303457 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01376337 0,05295105 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01376337 0,0528678 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01376337 0,0527848 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01376337 0,05270207 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01376337 0,05261959 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01376337 0,05253737 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01376337 0,05245541 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01376337 0,05237371 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01376337 0,05229225 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01376337 0,05221105 ! neural plate development GO:0001840 9 6 0,000 0,01376337 0,05213011 ! catecholamine transport GO:0051937 9 6 0,000 0,01376337 0,05204941 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01376337 0,05196896 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01376337 0,05188876 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01376337 0,05180881 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01376337 0,05172911 ! maternal placenta development GO:0001893 12 6 0,000 0,01376337 0,05164965 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01376337 0,05157043 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01376337 0,05149145 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01376337 0,05141272 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01376337 0,05133423 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01376337 0,05125597 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01376337 0,05117796 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01376337 0,05110018 GO:0055081|anion homeostasis, ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01409554 0,05225403 ! protein oligomerization GO:0051259 149 79 1,000 0,01444024 0,05345076 ! meiosis GO:0007126 143 81 1,000 0,01514051 0,05595804 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01514051 0,05587351 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01549605 0,05709931 ! meiotic cell cycle GO:0051321 144 82 1,000 0,01549605 0,05701332 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01585516 0,05824686 GO:0045937|positive regulation of phosphate metabolic process, ! tRNA transcription GO:0009304 17 7 0,000 0,016039 0,05883377 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,016039 0,05874556 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,016039 0,05865762 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,016039 0,05856994 ! regulation of helicase activity GO:0051095 16 7 0,000 0,016039 0,05848252 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,016039 0,05839536 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,016039 0,05830846 ! sleep GO:0030431 16 7 0,000 0,016039 0,05822182 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,016039 0,05813544 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,016039 0,05804932 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,016039 0,05796344 ! prostate gland development GO:0030850 14 7 0,000 0,016039 0,05787783 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,016039 0,05779246 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,016039 0,05770735 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,016039 0,05762248 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,016039 0,05753787 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,016039 0,0574535 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,016039 0,05736938 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,016039 0,05728551 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,016039 0,05720188 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,016039 0,0571185 ! glycolipid transport GO:0046836 11 7 0,000 0,016039 0,05703535 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,016039 0,05695245 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,016039 0,05686979 ! neuron adhesion GO:0007158 14 7 0,000 0,016039 0,05678737 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,016039 0,05670519 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,016039 0,05662325 ! pericardium development GO:0060039 16 7 0,000 0,016039 0,05654154 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,016039 0,05646007 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,016039 0,05637883 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,016039 0,05629783 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,016039 0,05621706 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,016039 0,05613652 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,016039 0,05605621 ! lipoprotein transport GO:0042953 14 7 0,000 0,016039 0,05597613 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,016039 0,05589627 ! rhythmic behavior GO:0007622 17 7 0,000 0,016039 0,05581665 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,016039 0,05573725 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,016039 0,05565808 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,016039 0,05557913 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,016039 0,05550041 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,016039 0,05542191 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,016039 0,05534363 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,016039 0,05526557 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,016039 0,05518773 ! mechanosensory behavior GO:0007638 16 7 0,000 0,016039 0,05511011 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,016039 0,05503271 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,016039 0,05495552 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,016039 0,05487855 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,016039 0,0548018 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,016039 0,05472526 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,016039 0,05464894 ! spinal cord patterning GO:0021511 14 7 0,000 0,016039 0,05457282 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,016039 0,05449692 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,016039 0,05442123 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,016039 0,05434575 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,016039 0,05427048 ! adrenal gland development GO:0030325 17 7 0,000 0,016039 0,05419542 ! cysteine metabolic process GO:0006534 13 7 0,000 0,016039 0,05412056 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,016039 0,05404591 ! ovulation GO:0030728 10 7 0,000 0,016039 0,05397147 ! adenohypophysis development GO:0021984 11 7 0,000 0,016039 0,05389723 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,016039 0,0538232 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,016039 0,05374937 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,016039 0,05367574 ! microtubule nucleation GO:0007020 21 7 0,000 0,016039 0,05360231 ! proline biosynthetic process GO:0006561 10 7 0,000 0,016039 0,05352908 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,016039 0,05345605 ! thyroid hormone generation GO:0006590 13 7 0,000 0,016039 0,05338323 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,016039 0,0533106 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,016039 0,05323816 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,016039 0,05316593 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,016039 0,05309389 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,016039 0,05302204 ! galactose metabolic process GO:0006012 13 7 0,000 0,016039 0,05295039 ! response to dietary excess GO:0002021 8 7 0,000 0,016039 0,05287893 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,016039 0,05280767 ! intracellular pH reduction GO:0051452 13 7 0,000 0,016039 0,05273659 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,016039 0,05266571 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,016039 0,05259502 ! organ growth GO:0035265 15 7 0,000 0,016039 0,05252451 ! nucleoside transport GO:0015858 11 7 0,000 0,016039 0,0524542 ! nucleoside salvage GO:0043174 11 7 0,000 0,016039 0,05238407 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,016039 0,05231414 ! male sex determination GO:0030238 15 7 0,000 0,016039 0,05224438 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,016039 0,05217482 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,016039 0,05210544 ! parturition GO:0007567 16 7 0,000 0,016039 0,05203624 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,016039 0,05196723 ! rRNA modification GO:0000154 14 7 0,000 0,016039 0,05189839 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,016039 0,05182975 ! spindle checkpoint GO:0031577 16 7 0,000 0,016039 0,05176128 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,016039 0,05169299 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,016039 0,05162489 ! monocyte differentiation GO:0030224 16 7 0,000 0,016039 0,05155696 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,016039 0,05148921 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,016039 0,05142164 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,016039 0,05135424 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,016039 0,05128703 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,016039 0,05121998 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,016039 0,05115312 ! fibrinolysis GO:0042730 11 7 0,000 0,016039 0,05108642 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,016039 0,05101991 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,016039 0,05095356 ! eating behavior GO:0042755 8 7 0,000 0,016039 0,05088739 ! B cell lineage commitment GO:0002326 21 7 0,000 0,016039 0,05082138 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,016039 0,05075555 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,016039 0,05068989 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,016039 0,0506244 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,016039 0,05055908 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,016039 0,05049393 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,016039 0,05042894 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,016039 0,05036412 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,016039 0,05029947 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,016039 0,05023498 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,016039 0,05017066 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,016039 0,05010651 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,016039 0,05004251 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,016039 0,04997868 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,016039 0,04991502 ! histone ubiquitination GO:0016574 9 7 0,000 0,016039 0,04985151 ! regulation of meiosis GO:0040020 12 7 0,000 0,016039 0,04978817 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,016039 0,04972498 ! T cell lineage commitment GO:0002360 16 7 0,000 0,016039 0,04966196 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,016039 0,0495991 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,016039 0,04953639 ! membrane to membrane docking GO:0022614 14 7 0,000 0,016039 0,04947385 ! transcription termination GO:0006353 14 7 0,000 0,016039 0,04941146 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,016039 0,04934923 ! anaphase GO:0051322 18 7 0,000 0,016039 0,04928715 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,016039 0,04922524 ! axonal fasciculation GO:0007413 19 7 0,000 0,016039 0,04916347 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,016039 0,04910186 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,016039 0,04904041 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,016039 0,04897911 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,016039 0,04891796 ! diuresis GO:0030146 12 7 0,000 0,016039 0,04885697 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,016039 0,04879612 ! thiamin metabolic process GO:0006772 7 7 0,000 0,016039 0,04873543 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,016039 0,04867489 ! antibiotic transport GO:0042891 9 7 0,000 0,016039 0,0486145 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,016039 0,04855426 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,016039 0,04849417 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,016039 0,04843422 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,016039 0,04837443 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,016039 0,04831478 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,016039 0,04825528 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,016039 0,04819593 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,016039 0,04813672 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,016039 0,04807765 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,016039 0,04801873 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,016039 0,04795996 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,016039 0,04790133 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,016039 0,04784284 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,016039 0,0477845 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,016039 0,04772629 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,016039 0,04766823 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,016039 0,04761031 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,016039 0,04755253 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,016039 0,04749489 ! muscle adaptation GO:0043500 13 7 0,000 0,016039 0,04743739 ! embryonic heart tube development GO:0035050 14 7 0,000 0,016039 0,04738003 ! retina homeostasis GO:0001895 12 7 0,000 0,016039 0,04732281 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,016039 0,04726573 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,016039 0,04720878 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,016039 0,04715197 ! negative regulation of growth GO:0045926 168 85 1,000 0,01658405 0,04869572 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01695379 0,04972162 GO:0002696|positive regulation of leukocyte activation, ! regulation of DNA binding GO:0051101 167 89 1,000 0,01808397 0,0529726 ! regulation of neurological system process GO:0031644 175 89 1,000 0,01808397 0,05290916 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01830945 0,05350477 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01830945 0,05344084 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01830945 0,05337707 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01830945 0,05331345 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01830945 0,05324998 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01830945 0,05318666 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01830945 0,0531235 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01830945 0,05306048 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01830945 0,05299761 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01830945 0,05293489 ! meiotic prophase I GO:0007128 14 8 0,000 0,01830945 0,05287232 ! response to zinc ion GO:0010043 12 8 0,000 0,01830945 0,0528099 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01830945 0,05274762 ! oligopeptide transport GO:0006857 16 8 0,000 0,01830945 0,05268549 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01830945 0,05262351 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01830945 0,05256167 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01830945 0,05249998 ! signal peptide processing GO:0006465 12 8 0,000 0,01830945 0,05243843 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01830945 0,05237703 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01830945 0,05231577 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01830945 0,05225466 ! succinate metabolic process GO:0006105 17 8 0,000 0,01830945 0,05219368 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01830945 0,05213285 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01830945 0,05207216 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01830945 0,05201161 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01830945 0,0519512 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01830945 0,05189093 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01830945 0,0518308 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01830945 0,05177082 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01830945 0,05171096 ! reflex GO:0060004 17 8 0,000 0,01830945 0,05165125 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01830945 0,05159168 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01830945 0,05153224 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01830945 0,05147294 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01830945 0,05141378 ! pigment granule organization GO:0048753 17 8 0,000 0,01830945 0,05135475 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01830945 0,05129585 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01830945 0,0512371 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01830945 0,05117847 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01830945 0,05111998 ! histidine catabolic process GO:0006548 10 8 0,000 0,01830945 0,05106163 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01830945 0,0510034 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01830945 0,05094531 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01830945 0,05088735 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01830945 0,05082953 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01830945 0,05077183 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01830945 0,05071427 ! melanin metabolic process GO:0006582 17 8 0,000 0,01830945 0,05065683 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01830945 0,05059953 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01830945 0,05054236 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01830945 0,05048531 ! macrophage activation GO:0042116 13 8 0,000 0,01830945 0,05042839 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01830945 0,0503716 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01830945 0,05031494 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01830945 0,05025841 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01830945 0,050202 ! purine salvage GO:0043101 12 8 0,000 0,01830945 0,05014572 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01830945 0,05008957 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01830945 0,05003354 ! osteoblast development GO:0002076 17 8 0,000 0,01830945 0,04997764 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01830945 0,04992186 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01830945 0,0498662 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01830945 0,04981067 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01830945 0,04975527 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01830945 0,04969998 ! response to UV-B GO:0010224 17 8 0,000 0,01830945 0,04964482 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01830945 0,04958978 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01830945 0,04953487 ! intermediate filament organization GO:0045109 12 8 0,000 0,01830945 0,04948007 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01830945 0,0494254 ! cellular extravasation GO:0045123 13 8 0,000 0,01830945 0,04937084 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01830945 0,04931641 ! response to antibiotic GO:0046677 11 8 0,000 0,01830945 0,0492621 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01830945 0,0492079 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01830945 0,04915383 ! DNA topological change GO:0006265 12 8 0,000 0,01830945 0,04909987 ! response to tropane GO:0014073 15 8 0,000 0,01830945 0,04904604 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01830945 0,04899232 ! melanosome transport GO:0032402 13 8 0,000 0,01830945 0,04893871 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01830945 0,04888523 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01830945 0,04883186 ! mast cell activation GO:0045576 14 8 0,000 0,01830945 0,04877861 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01830945 0,04872547 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01830945 0,04867245 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01830945 0,04861955 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01830945 0,04856676 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01830945 0,04851408 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01830945 0,04846152 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01830945 0,04840907 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01830945 0,04835674 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01830945 0,04830452 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01830945 0,04825241 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01830945 0,04820041 ! response to tumor cell GO:0002347 16 8 0,000 0,01830945 0,04814853 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01830945 0,04809676 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01830945 0,0480451 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01830945 0,04799355 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01830945 0,04794211 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01830945 0,04789078 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01830945 0,04783956 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01830945 0,04778845 ! hormone catabolic process GO:0042447 17 8 0,000 0,01830945 0,04773744 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01830945 0,04768655 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01830945 0,04763577 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01830945 0,04758509 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01830945 0,04753452 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01830945 0,04748406 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01830945 0,04743371 ! adult feeding behavior GO:0008343 10 8 0,000 0,01830945 0,04738346 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01830945 0,04733332 ! ATP catabolic process GO:0006200 11 8 0,000 0,01830945 0,04728328 ! blastocyst growth GO:0001832 19 8 0,000 0,01830945 0,04723335 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01830945 0,04718353 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01830945 0,04713381 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01830945 0,04708419 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01830945 0,04703468 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01830945 0,04698528 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01830945 0,04693598 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01830945 0,04688678 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01830945 0,04683768 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01830945 0,04678869 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01830945 0,0467398 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01830945 0,04669101 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01830945 0,04664232 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01830945 0,04659373 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01830945 0,04654525 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01830945 0,04649687 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01830945 0,04644858 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01830945 0,0464004 ! oxidative phosphorylation GO:0006119 152 90 1,000 0,01846763 0,04675277 ! ossification GO:0001503 205 91 1,000 0,01885472 0,04768332 ! bone development GO:0060348 206 92 1,000 0,01924523 0,04862058 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,01924523 0,04857035 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,01963914 0,04951334 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,01963914 0,04946229 ! regulation of membrane potential GO:0042391 179 94 1,000 0,02003643 0,05041093 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,02043709 0,05136607 ! axon extension GO:0048675 16 9 0,000 0,02057472 0,05165883 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02057472 0,05160579 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02057472 0,05155286 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02057472 0,05150004 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02057472 0,05144733 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02057472 0,05139472 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02057472 0,05134223 ! reproductive behavior GO:0019098 22 9 0,000 0,02057472 0,05128984 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02057472 0,05123755 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02057472 0,05118538 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02057472 0,0511333 ! UTP metabolic process GO:0046051 10 9 0,000 0,02057472 0,05108134 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02057472 0,05102948 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02057472 0,05097773 ! artery development GO:0060840 25 9 0,000 0,02057472 0,05092608 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02057472 0,05087453 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02057472 0,05082309 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02057472 0,05077176 ! equilibrioception GO:0050957 20 9 0,000 0,02057472 0,05072052 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02057472 0,05066939 ! chemosensory behavior GO:0007635 21 9 0,000 0,02057472 0,05061837 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02057472 0,05056744 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02057472 0,05051662 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02057472 0,0504659 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02057472 0,05041528 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02057472 0,05036477 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02057472 0,05031435 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02057472 0,05026404 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02057472 0,05021382 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02057472 0,05016371 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02057472 0,0501137 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02057472 0,05006378 ! protein targeting to ER GO:0045047 25 9 0,000 0,02057472 0,05001397 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02057472 0,04996425 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02057472 0,04991464 ! T cell selection GO:0045058 27 9 0,000 0,02057472 0,04986512 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02057472 0,0498157 ! glycine catabolic process GO:0006546 15 9 0,000 0,02057472 0,04976637 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02057472 0,04971715 ! endosome organization GO:0007032 20 9 0,000 0,02057472 0,04966802 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02057472 0,04961899 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02057472 0,04957006 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02057472 0,04952122 ! mannose metabolic process GO:0006013 13 9 0,000 0,02057472 0,04947248 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02057472 0,04942383 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02057472 0,04937528 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02057472 0,04932683 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02057472 0,04927847 ! receptor clustering GO:0043113 20 9 0,000 0,02057472 0,0492302 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02057472 0,04918203 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02057472 0,04913396 ! retinol metabolic process GO:0042572 20 9 0,000 0,02057472 0,04908598 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02057472 0,04903809 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02057472 0,04899029 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02057472 0,04894259 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02057472 0,04889498 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02057472 0,04884746 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02057472 0,04880004 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02057472 0,0487527 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02057472 0,04870546 ! response to amine stimulus GO:0014075 13 9 0,000 0,02057472 0,04865831 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02057472 0,04861126 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02057472 0,04856429 ! erythrocyte development GO:0048821 17 9 0,000 0,02057472 0,04851741 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02057472 0,04847063 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02057472 0,04842393 ! renal water homeostasis GO:0003091 15 9 0,000 0,02057472 0,04837732 ! postreplication repair GO:0006301 25 9 0,000 0,02057472 0,04833081 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02057472 0,04828438 ! icosanoid secretion GO:0032309 15 9 0,000 0,02057472 0,04823804 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02057472 0,04819179 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02057472 0,04814563 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02057472 0,04809956 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02057472 0,04805357 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02057472 0,04800768 ! sterol catabolic process GO:0016127 14 9 0,000 0,02057472 0,04796187 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02057472 0,04791615 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02057472 0,04787051 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02057472 0,04782497 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02057472 0,0477795 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02057472 0,04773413 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02057472 0,04768884 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02057472 0,04764364 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02057472 0,04759852 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02057472 0,04755349 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02057472 0,04750854 ! purine base metabolic process GO:0006144 25 9 0,000 0,02057472 0,04746368 ! pigment granule transport GO:0051904 17 9 0,000 0,02057472 0,0474189 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02057472 0,04737421 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02057472 0,0473296 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02057472 0,04728508 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02057472 0,04724064 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02057472 0,04719628 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02057472 0,04715201 ! mitochondrion localization GO:0051646 18 9 0,000 0,02057472 0,04710782 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02283483 0,05223359 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02283483 0,05218473 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02283483 0,05213596 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02283483 0,05208728 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02283483 0,05203869 ! associative learning GO:0008306 21 10 0,000 0,02283483 0,05199019 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02283483 0,05194179 ! phosphate transport GO:0006817 24 10 0,000 0,02283483 0,05189347 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02283483 0,05184524 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02283483 0,0517971 ! CTP metabolic process GO:0046036 11 10 0,000 0,02283483 0,05174905 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02283483 0,05170109 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02283483 0,05165322 ! GTP metabolic process GO:0046039 11 10 0,000 0,02283483 0,05160544 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02283483 0,05155774 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02283483 0,05151014 ! social behavior GO:0035176 29 10 0,000 0,02283483 0,05146262 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02283483 0,05141519 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02283483 0,05136784 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02283483 0,05132059 ! androgen metabolic process GO:0008209 17 10 0,000 0,02283483 0,05127342 ! phospholipid efflux GO:0033700 19 10 0,000 0,02283483 0,05122633 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02283483 0,05117934 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02283483 0,05113243 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02283483 0,0510856 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02283483 0,05103886 ! pathogenesis GO:0009405 17 10 0,000 0,02283483 0,05099221 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02283483 0,05094564 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02283483 0,05089916 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02283483 0,05085276 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02283483 0,05080645 ! endoderm development GO:0007492 18 10 0,000 0,02283483 0,05076022 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02283483 0,05071407 ! arginine catabolic process GO:0006527 17 10 0,000 0,02283483 0,05066801 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02283483 0,05062203 ! proline metabolic process GO:0006560 13 10 0,000 0,02283483 0,05057614 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02283483 0,05053032 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02283483 0,0504846 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02283483 0,05043895 ! V(D)J recombination GO:0033151 34 10 0,000 0,02283483 0,05039339 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02283483 0,0503479 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02283483 0,05030251 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02283483 0,05025719 ! B cell proliferation GO:0042100 19 10 0,000 0,02283483 0,05021195 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02283483 0,0501668 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02283483 0,05012172 ! multicellular organism growth GO:0035264 19 10 0,000 0,02283483 0,05007673 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02283483 0,05003182 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02283483 0,04998699 ! ruffle organization GO:0031529 17 10 0,000 0,02283483 0,04994224 ! epithelial cell development GO:0002064 21 10 0,000 0,02283483 0,04989757 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02283483 0,04985297 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02283483 0,04980846 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02283483 0,04976403 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02283483 0,04971968 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02283483 0,0496754 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02283483 0,04963121 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02283483 0,04958709 ! motor axon guidance GO:0008045 22 10 0,000 0,02283483 0,04954305 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02283483 0,04949909 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02283483 0,04945521 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02283483 0,04941141 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02283483 0,04936768 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02283483 0,04932403 ! segment specification GO:0007379 15 10 0,000 0,02283483 0,04928046 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02283483 0,04923696 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02283483 0,04919354 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02283483 0,0491502 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02283483 0,04910693 ! response to dsRNA GO:0043331 23 10 0,000 0,02283483 0,04906374 ! DNA ligation GO:0006266 18 10 0,000 0,02283483 0,04902063 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02283483 0,04897759 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02283483 0,04893463 ! melanosome localization GO:0032400 16 10 0,000 0,02283483 0,04889174 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02283483 0,04884893 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02283483 0,04880619 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02283483 0,04876353 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02283483 0,04872094 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02283483 0,04867843 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02283483 0,04863599 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02283483 0,04859362 ! protein sumoylation GO:0016925 17 10 0,000 0,02283483 0,04855133 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02283483 0,04850911 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02283483 0,04846697 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02283483 0,04842489 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02283483 0,0483829 ! salivary gland development GO:0007431 28 10 0,000 0,02283483 0,04834097 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02283483 0,04829912 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02283483 0,04825733 ! midbrain development GO:0030901 14 10 0,000 0,02283483 0,04821562 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02283483 0,04817399 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02283483 0,04813242 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02283483 0,04809093 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02283483 0,04804951 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02283483 0,04800816 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02283483 0,04796688 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02283483 0,04792567 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02283483 0,04788453 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02283483 0,04784346 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02283483 0,04780247 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02283483 0,04776154 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02283483 0,04772068 ! blastocyst formation GO:0001825 18 10 0,000 0,02283483 0,0476799 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02283483 0,04763918 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02283483 0,04759853 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02283483 0,04755795 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02283483 0,04751744 ! response to nicotine GO:0035094 20 10 0,000 0,02283483 0,047477 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02283483 0,04743663 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02508978 0,05207675 ! respiratory burst GO:0045730 17 11 0,000 0,02508978 0,05203254 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02508978 0,05198841 ! neuron fate specification GO:0048665 18 11 0,000 0,02508978 0,05194435 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02508978 0,05190037 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02508978 0,05185646 ! thyroid gland development GO:0030878 26 11 0,000 0,02508978 0,05181262 ! synapsis GO:0007129 14 11 0,000 0,02508978 0,05176886 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02508978 0,05172517 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02508978 0,05168156 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02508978 0,05163802 ! response to pain GO:0048265 27 11 0,000 0,02508978 0,05159455 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02508978 0,05155116 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02508978 0,05150784 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02508978 0,05146459 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02508978 0,05142142 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02508978 0,05137832 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02508978 0,05133529 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02508978 0,05129233 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02508978 0,05124944 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02508978 0,05120663 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02508978 0,05116388 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02508978 0,05112121 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02508978 0,05107861 ! UV protection GO:0009650 20 11 0,000 0,02508978 0,05103608 ! adult heart development GO:0007512 16 11 0,000 0,02508978 0,05099362 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02508978 0,05095123 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02508978 0,05090891 ! macroautophagy GO:0016236 19 11 0,000 0,02508978 0,05086666 ! temperature homeostasis GO:0001659 18 11 0,000 0,02508978 0,05082449 ! behavioral fear response GO:0001662 27 11 0,000 0,02508978 0,05078238 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02508978 0,05074034 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02508978 0,05069837 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02508978 0,05065647 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02508978 0,05061464 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02508978 0,05057288 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02508978 0,05053119 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02508978 0,05048956 ! regulation of organ growth GO:0046620 14 11 0,000 0,02508978 0,05044801 ! pigment granule localization GO:0051875 20 11 0,000 0,02508978 0,05040652 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02508978 0,0503651 ! vasoconstriction GO:0042310 20 11 0,000 0,02508978 0,05032375 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02508978 0,05028247 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02508978 0,05024126 ! embryonic axis specification GO:0000578 19 11 0,000 0,02508978 0,05020011 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02508978 0,05015903 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02508978 0,05011801 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02508978 0,05007707 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02508978 0,05003619 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02508978 0,04999538 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02508978 0,04995463 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02508978 0,04991395 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02508978 0,04987334 ! prophase GO:0051324 17 11 0,000 0,02508978 0,04983279 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02508978 0,04979231 ! nucleosome positioning GO:0016584 15 11 0,000 0,02508978 0,04975189 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02508978 0,04971154 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02508978 0,04967126 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02508978 0,04963104 ! apical protein localization GO:0045176 18 11 0,000 0,02508978 0,04959088 ! acid secretion GO:0046717 20 11 0,000 0,02508978 0,04955079 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02508978 0,04951077 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02508978 0,04947081 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02508978 0,04943091 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02508978 0,04939108 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02508978 0,04935131 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,02508978 0,04931161 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02508978 0,04927197 ! oocyte development GO:0048599 20 11 0,000 0,02508978 0,04923239 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02508978 0,04919288 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02508978 0,04915343 ! embryonic gut development GO:0048566 19 11 0,000 0,02508978 0,04911405 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02508978 0,04907472 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02508978 0,04903547 ! activation of innate immune response GO:0002218 16 11 0,000 0,02508978 0,04899627 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02508978 0,04895713 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02508978 0,04891806 ! lysogeny GO:0030069 22 11 0,000 0,02508978 0,04887905 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02508978 0,0488401 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02508978 0,04880122 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02508978 0,0487624 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02508978 0,04872363 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02733959 0,05305054 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02733959 0,05300843 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02733959 0,0529664 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02733959 0,05292443 ! virus-host interaction GO:0019048 30 12 0,000 0,02733959 0,05288252 ! mating GO:0007618 17 12 0,000 0,02733959 0,05284069 ! protein complex disassembly GO:0043241 28 12 0,000 0,02733959 0,05279891 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02733959 0,05275721 ! hippocampus development GO:0021766 29 12 0,000 0,02733959 0,05271557 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02733959 0,052674 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02733959 0,05263249 ! T cell proliferation GO:0042098 32 12 0,000 0,02733959 0,05259104 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02733959 0,05254967 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02733959 0,05250835 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02733959 0,05246711 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02733959 0,05242592 ! drug transport GO:0015893 16 12 0,000 0,02733959 0,05238481 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02733959 0,05234375 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02733959 0,05230276 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02733959 0,05226184 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02733959 0,05222097 ! focal adhesion formation GO:0048041 37 12 0,000 0,02733959 0,05218018 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02733959 0,05213944 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02733959 0,05209877 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02733959 0,05205817 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02733959 0,05201762 ! lipid digestion GO:0044241 21 12 0,000 0,02733959 0,05197714 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02733959 0,05193672 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02733959 0,05189637 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02733959 0,05185608 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02733959 0,05181585 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02733959 0,05177568 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02733959 0,05173557 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02733959 0,05169553 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02733959 0,05165555 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02733959 0,05161563 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02733959 0,05157577 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02733959 0,05153598 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02733959 0,05149624 ! cranial nerve development GO:0021545 23 12 0,000 0,02733959 0,05145657 ! fucose catabolic process GO:0019317 25 12 0,000 0,02733959 0,05141696 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02733959 0,05137741 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02733959 0,05133791 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02733959 0,05129848 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02733959 0,05125911 ! zymogen activation GO:0031638 18 12 0,000 0,02733959 0,05121981 ! T cell homeostasis GO:0043029 28 12 0,000 0,02733959 0,05118056 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02733959 0,05114137 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02733959 0,05110224 ! oocyte differentiation GO:0009994 21 12 0,000 0,02733959 0,05106317 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02733959 0,05102416 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02733959 0,05098521 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02733959 0,05094632 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02733959 0,05090749 ! defense response to fungus GO:0050832 15 12 0,000 0,02733959 0,05086872 ! embryonic placenta development GO:0001892 21 12 0,000 0,02733959 0,05083001 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02733959 0,05079135 ! response to cold GO:0009409 17 12 0,000 0,02733959 0,05075276 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02733959 0,05071422 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02733959 0,05067574 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02958428 0,05479484 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02958428 0,05475333 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02958428 0,05471188 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02958428 0,05467049 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02958428 0,05462917 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02958428 0,05458791 ! peroxisomal transport GO:0043574 28 13 0,000 0,02958428 0,05454671 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02958428 0,05450558 ! cartilage condensation GO:0001502 22 13 0,000 0,02958428 0,0544645 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02958428 0,05442349 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02958428 0,05438254 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02958428 0,05434165 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02958428 0,05430082 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02958428 0,05426005 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02958428 0,05421935 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02958428 0,05417871 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02958428 0,05413812 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02958428 0,0540976 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02958428 0,05405714 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02958428 0,05401674 ! methionine metabolic process GO:0006555 31 13 0,000 0,02958428 0,05397639 ! plasma membrane organization GO:0007009 27 13 0,000 0,02958428 0,05393611 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02958428 0,05389589 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02958428 0,05385573 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02958428 0,05381563 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02958428 0,05377559 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02958428 0,05373561 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02958428 0,05369569 ! exocrine system development GO:0035272 34 13 0,000 0,02958428 0,05365582 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02958428 0,05361602 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02958428 0,05357627 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02958428 0,05353659 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02958428 0,05349696 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02958428 0,05345739 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02958428 0,05341788 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02958428 0,05337843 ! protein homotetramerization GO:0051289 24 13 0,000 0,02958428 0,05333904 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02958428 0,0532997 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02958428 0,05326042 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02958428 0,0532212 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02958428 0,05318204 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02958428 0,05314294 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02958428 0,05310389 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02958428 0,0530649 ! histone methylation GO:0016571 29 13 0,000 0,02958428 0,05302597 ! chromatin silencing GO:0006342 29 13 0,000 0,02958428 0,05298709 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02958428 0,05294827 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02958428 0,05290951 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02958428 0,05287081 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02958428 0,05283216 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02958428 0,05279357 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02958428 0,05275503 ! spleen development GO:0048536 24 13 0,000 0,02958428 0,05271655 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02958428 0,05267813 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02958428 0,05263976 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02958428 0,05260145 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02958428 0,05256319 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02958428 0,05252499 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02958428 0,05248685 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02958428 0,05244876 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02958428 0,05241073 ! insulin secretion GO:0030073 24 13 0,000 0,02958428 0,05237275 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02958428 0,05233482 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02958428 0,05229696 ! acrosome reaction GO:0007340 19 13 0,000 0,02958428 0,05225914 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02958428 0,05222138 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02958428 0,05218368 ! rRNA transcription GO:0009303 28 14 0,000 0,03182385 0,05609355 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03182385 0,05605311 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03182385 0,05601272 ! water transport GO:0006833 21 14 0,000 0,03182385 0,0559724 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03182385 0,05593213 ! non-recombinational repair GO:0000726 29 14 0,000 0,03182385 0,05589192 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03182385 0,05585177 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03182385 0,05581167 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03182385 0,05577163 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03182385 0,05573165 ! palate development GO:0060021 32 14 0,000 0,03182385 0,05569173 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03182385 0,05565187 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03182385 0,05561206 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03182385 0,05557231 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03182385 0,05553261 ! arginine metabolic process GO:0006525 21 14 0,000 0,03182385 0,05549297 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03182385 0,05545339 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03182385 0,05541387 ! regulation of heart rate GO:0002027 25 14 0,000 0,03182385 0,0553744 ! fear response GO:0042596 34 14 0,000 0,03182385 0,05533499 ! organic alcohol transport GO:0015850 29 14 0,000 0,03182385 0,05529563 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03182385 0,05525633 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03182385 0,05521709 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03182385 0,0551779 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03182385 0,05513876 ! bone mineralization GO:0030282 18 14 0,000 0,03182385 0,05509969 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03182385 0,05506066 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03182385 0,0550217 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03182385 0,05498278 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03182385 0,05494393 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03182385 0,05490513 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03182385 0,05486638 ! ribosome assembly GO:0042255 18 14 0,000 0,03182385 0,05482768 ! cerebellum development GO:0021549 23 14 0,000 0,03182385 0,05478905 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03182385 0,05475046 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03182385 0,05471193 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03182385 0,05467346 ! response to gamma radiation GO:0010332 30 14 0,000 0,03182385 0,05463504 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03182385 0,05459667 ! NADP metabolic process GO:0006739 24 14 0,000 0,03182385 0,05455836 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03182385 0,0545201 ! oxygen transport GO:0015671 22 14 0,000 0,03182385 0,05448189 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03182385 0,05444374 ! male genitalia development GO:0030539 26 14 0,000 0,03182385 0,05440564 ! regulation of axon extension GO:0030516 43 14 0,000 0,03182385 0,05436759 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,03182385 0,0543296 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03182385 0,05429166 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03405831 0,05806312 ! lactation GO:0007595 30 15 0,000 0,03405831 0,05802263 ! reproductive cellular process GO:0048610 22 15 0,000 0,03405831 0,05798219 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03405831 0,05794182 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03405831 0,0579015 ! superoxide anion generation GO:0042554 22 15 0,000 0,03405831 0,05786123 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03405831 0,05782102 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03405831 0,05778087 ! copper ion transport GO:0006825 22 15 0,000 0,03405831 0,05774077 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03405831 0,05770073 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03405831 0,05766074 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03405831 0,05762081 ! sulfate transport GO:0008272 27 15 0,000 0,03405831 0,05758093 ! response to cAMP GO:0051591 25 15 0,000 0,03405831 0,05754111 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03405831 0,05750135 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03405831 0,05746164 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03405831 0,05742198 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03405831 0,05738238 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03405831 0,05734283 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03405831 0,05730334 ! vesicle coating GO:0006901 38 15 0,000 0,03405831 0,0572639 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03405831 0,05722452 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03405831 0,05718519 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,03405831 0,05714591 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03405831 0,05710669 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03405831 0,05706752 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,03405831 0,05702841 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03405831 0,05698935 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03405831 0,05695034 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03405831 0,05691139 ! histone deacetylation GO:0016575 24 15 0,000 0,03405831 0,05687249 ! water homeostasis GO:0030104 28 15 0,000 0,03405831 0,05683364 ! cofactor transport GO:0051181 30 15 0,000 0,03405831 0,05679485 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03405831 0,0567561 ! muscle maintenance GO:0046716 26 15 0,000 0,03405831 0,05671742 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03405831 0,05667878 ! intestinal absorption GO:0050892 31 15 0,000 0,03405831 0,0566402 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03405831 0,05660167 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03405831 0,05656319 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03405831 0,05652476 ! cell killing GO:0001906 32 15 0,000 0,03405831 0,05648639 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03405831 0,05644807 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03405831 0,0564098 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03405831 0,05637158 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03405831 0,05633341 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03405831 0,0562953 ! actin filament polymerization GO:0030041 27 15 0,000 0,03405831 0,05625723 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03405831 0,05621922 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03628768 0,05985874 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03628768 0,05981835 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03628768 0,05977801 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03628768 0,05973773 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03628768 0,0596975 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03628768 0,05965733 ! bone remodeling GO:0046849 28 16 0,000 0,03628768 0,05961721 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03628768 0,05957715 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03628768 0,05953714 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03628768 0,05949718 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03628768 0,05945727 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03628768 0,05941742 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03628768 0,05937763 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03628768 0,05933788 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03628768 0,05929819 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03628768 0,05925855 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03628768 0,05921897 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03628768 0,05917944 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03628768 0,05913996 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03628768 0,05910053 ! pituitary gland development GO:0021983 30 16 0,000 0,03628768 0,05906116 ! response to osmotic stress GO:0006970 27 16 0,000 0,03628768 0,05902183 ! lysosomal transport GO:0007041 31 16 0,000 0,03628768 0,05898256 ! fructose metabolic process GO:0006000 25 16 0,000 0,03628768 0,05894335 ! L-amino acid transport GO:0015807 33 16 0,000 0,03628768 0,05890418 ! stem cell development GO:0048864 46 16 0,000 0,03628768 0,05886507 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03628768 0,05882601 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03628768 0,058787 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03628768 0,05874804 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03628768 0,05870914 ! axon cargo transport GO:0008088 46 16 0,000 0,03628768 0,05867028 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03628768 0,05863148 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03628768 0,05859273 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03628768 0,05855403 ! DNA replication initiation GO:0006270 28 16 0,000 0,03628768 0,05851538 ! neuron recognition GO:0008038 40 16 0,000 0,03628768 0,05847678 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03628768 0,05843823 ! tissue regeneration GO:0042246 27 16 0,000 0,03628768 0,05839973 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03628768 0,05836129 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03628768 0,05832289 ! biomineral formation GO:0031214 22 16 0,000 0,03628768 0,05828455 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03628768 0,05824625 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03628768 0,05820801 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03628768 0,05816981 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03628768 0,05813167 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03628768 0,05809357 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03628768 0,05805553 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03628768 0,05801754 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03628768 0,05797959 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03628768 0,0579417 ! peptide hormone processing GO:0016486 27 16 0,000 0,03628768 0,05790385 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03851196 0,06141301 ! metencephalon development GO:0022037 32 17 0,000 0,03851196 0,06137294 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03851196 0,06133294 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03851196 0,06129298 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03851196 0,06125308 ! signal complex assembly GO:0007172 47 17 0,000 0,03851196 0,06121322 ! endothelial cell migration GO:0043542 31 17 0,000 0,03851196 0,06117342 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03851196 0,06113367 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03851196 0,06109398 ! glial cell development GO:0021782 28 17 0,000 0,03851196 0,06105433 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03851196 0,06101474 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03851196 0,06097519 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03851196 0,0609357 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03851196 0,06089626 ! myoblast differentiation GO:0045445 50 17 0,000 0,03851196 0,06085687 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03851196 0,06081753 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03851196 0,06077825 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03851196 0,06073901 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03851196 0,06069982 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03851196 0,06066069 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03851196 0,0606216 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03851196 0,06058257 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03851196 0,06054358 ! membrane budding GO:0006900 42 17 0,000 0,03851196 0,06050465 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03851196 0,06046576 ! regulation of protein binding GO:0043393 33 17 0,000 0,03851196 0,06042693 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03851196 0,06038814 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03851196 0,06034941 ! genitalia development GO:0048806 32 17 0,000 0,03851196 0,06031072 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03851196 0,06027208 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03851196 0,0602335 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03851196 0,06019496 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03851196 0,06015647 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03851196 0,06011803 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03851196 0,06007964 ! steroid catabolic process GO:0006706 34 17 0,000 0,03851196 0,0600413 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03851196 0,06000301 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03851196 0,05996477 ! gas transport GO:0015669 26 17 0,000 0,03851196 0,05992658 ! organic cation transport GO:0015695 32 17 0,000 0,03851196 0,05988843 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03851196 0,05985033 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03851196 0,05981228 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04073118 0,06321872 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04073118 0,06317858 ! limbic system development GO:0021761 40 18 0,000 0,04073118 0,06313849 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04073118 0,06309846 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04073118 0,06305847 ! adult walking behavior GO:0007628 36 18 0,000 0,04073118 0,06301853 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04073118 0,06297865 ! heart looping GO:0001947 34 18 0,000 0,04073118 0,06293881 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04073118 0,06289903 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04073118 0,06285929 ! centrosome cycle GO:0007098 26 18 0,000 0,04073118 0,06281961 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04073118 0,06277998 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04073118 0,06274039 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04073118 0,06270086 ! glycine metabolic process GO:0006544 30 18 0,000 0,04073118 0,06266138 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04073118 0,06262194 ! response to retinoic acid GO:0032526 31 18 0,000 0,04073118 0,06258256 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04073118 0,06254322 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04073118 0,06250393 ! DNA integration GO:0015074 32 18 0,000 0,04073118 0,0624647 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04073118 0,06242551 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04073118 0,06238637 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04073118 0,06234728 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04073118 0,06230824 ! neural crest cell migration GO:0001755 41 18 0,000 0,04073118 0,06226925 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04073118 0,06223031 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04073118 0,06219141 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04073118 0,06215257 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04073118 0,06211377 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04073118 0,06207502 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04073118 0,06203632 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,04073118 0,06199767 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04073118 0,06195907 ! detection of bacterium GO:0016045 22 18 0,000 0,04073118 0,06192051 ! nerve development GO:0021675 34 18 0,000 0,04073118 0,061882 ! defense response to virus GO:0051607 43 18 0,000 0,04073118 0,06184354 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04073118 0,06180513 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04073118 0,06176677 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04294533 0,06508402 ! positive regulation of translation GO:0045727 31 19 0,000 0,04294533 0,06504367 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04294533 0,06500337 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,04294533 0,06496312 ! neuron maturation GO:0042551 46 19 0,000 0,04294533 0,06492292 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04294533 0,06488277 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04294533 0,06484267 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04294533 0,06480262 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04294533 0,06476262 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04294533 0,06472267 ! inositol metabolic process GO:0006020 33 19 0,000 0,04294533 0,06468276 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04294533 0,06464291 ! memory GO:0007613 34 19 0,000 0,04294533 0,06460311 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04294533 0,06456335 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04294533 0,06452364 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04294533 0,06448398 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04294533 0,06444438 ! cerebral cortex development GO:0021987 40 19 0,000 0,04294533 0,06440481 ! pigmentation during development GO:0048066 42 19 0,000 0,04294533 0,0643653 ! response to vitamin A GO:0033189 32 19 0,000 0,04294533 0,06432584 ! heme metabolic process GO:0042168 40 19 0,000 0,04294533 0,06428642 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04294533 0,06424706 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04294533 0,06420774 ! response to fungus GO:0009620 26 19 0,000 0,04294533 0,06416847 ! peptide cross-linking GO:0018149 39 19 0,000 0,04294533 0,06412924 ! protein export from nucleus GO:0006611 40 19 0,000 0,04294533 0,06409007 ! heart process GO:0003015 32 19 0,000 0,04294533 0,06405094 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04294533 0,06401186 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04294533 0,06397283 ! visual learning GO:0008542 38 19 0,000 0,04294533 0,06393385 ! cellular pigmentation GO:0033059 37 19 0,000 0,04294533 0,06389491 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04294533 0,06385602 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04294533 0,06381718 ! vitamin transport GO:0051180 31 19 0,000 0,04294533 0,06377838 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04294533 0,06373964 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04294533 0,06370094 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04294533 0,06366228 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04294533 0,06362368 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04294533 0,06358512 ! cilium assembly GO:0042384 38 19 0,000 0,04294533 0,0635466 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04294533 0,06350814 ! protein secretion GO:0009306 45 20 0,000 0,04515444 0,0667346 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04515444 0,06669425 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04515444 0,06665395 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04515444 0,0666137 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04515444 0,0665735 ! skin development GO:0043588 42 20 0,000 0,04515444 0,06653335 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04515444 0,06649324 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04515444 0,06645319 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,04515444 0,06641318 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04515444 0,06637322 ! response to vitamin GO:0033273 36 20 0,000 0,04515444 0,06633331 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04515444 0,06629344 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04515444 0,06625363 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04515444 0,06621386 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04515444 0,06617414 ! response to alkaloid GO:0043279 38 20 0,000 0,04515444 0,06613447 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04515444 0,06609484 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04515444 0,06605526 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04515444 0,06601573 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04515444 0,06597625 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04515444 0,06593681 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04515444 0,06589742 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04515444 0,06585808 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04515444 0,06581879 ! body fluid secretion GO:0007589 33 20 0,000 0,04515444 0,06577954 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04515444 0,06574034 ! peptide secretion GO:0002790 38 20 0,000 0,04515444 0,06570118 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04515444 0,06566208 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04515444 0,06562301 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04515444 0,065584 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04515444 0,06554503 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04515444 0,06550611 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04515444 0,06546723 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04515444 0,0654284 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04515444 0,06538962 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04515444 0,06535088 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04515444 0,06531219 ! regulation of glucose import GO:0046324 30 20 0,000 0,04515444 0,06527354 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04515444 0,06523494 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04515444 0,06519639 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04515444 0,06515788 ! negative regulation of translation GO:0017148 32 20 0,000 0,04515444 0,06511941 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04515444 0,065081 ! regulation of cell killing GO:0031341 46 21 0,000 0,04735851 0,06821747 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04735851 0,06817727 ! hormone secretion GO:0046879 39 21 0,000 0,04735851 0,06813712 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04735851 0,06809701 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04735851 0,06805696 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04735851 0,06801695 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04735851 0,06797698 ! ovarian follicle development GO:0001541 39 21 0,000 0,04735851 0,06793707 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04735851 0,0678972 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04735851 0,06785738 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04735851 0,0678176 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04735851 0,06777787 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04735851 0,06773819 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04735851 0,06769855 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04735851 0,06765896 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,04735851 0,06761942 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04735851 0,06757992 ! diencephalon development GO:0021536 36 21 0,000 0,04735851 0,06754047 ! collagen fibril organization GO:0030199 62 21 0,000 0,04735851 0,06750107 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04735851 0,06746171 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04735851 0,06742239 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04735851 0,06738313 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04735851 0,0673439 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04735851 0,06730473 ! collagen catabolic process GO:0030574 29 21 0,000 0,04735851 0,0672656 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04735851 0,06722651 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04735851 0,06718747 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04735851 0,06714848 ! actin filament-based movement GO:0030048 47 21 0,000 0,04735851 0,06710953 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04955755 0,07018498 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04955755 0,07014432 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04955755 0,0701037 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04955755 0,07006313 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04955755 0,07002261 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04955755 0,06998213 ! microtubule-based transport GO:0010970 59 22 0,000 0,04955755 0,0699417 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04955755 0,06990132 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04955755 0,06986099 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04955755 0,0698207 ! cellular response to starvation GO:0009267 37 22 0,000 0,04955755 0,06978046 ! vacuolar transport GO:0007034 41 22 0,000 0,04955755 0,06974026 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04955755 0,06970011 ! fucose metabolic process GO:0006004 44 22 0,000 0,04955755 0,06966001 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04955755 0,06961995 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04955755 0,06957994 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04955755 0,06953997 ! ureteric bud development GO:0001657 50 22 0,000 0,04955755 0,06950005 ! cell aging GO:0007569 48 22 0,000 0,04955755 0,06946018 ! stem cell differentiation GO:0048863 57 22 0,000 0,04955755 0,06942035 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04955755 0,06938057 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04955755 0,06934083 ! cytolysis GO:0019835 27 22 0,000 0,04955755 0,06930114 ! renal system process GO:0003014 42 22 0,000 0,04955755 0,06926149 ! vasodilation GO:0042311 40 22 0,000 0,04955755 0,06922189 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04955755 0,06918234 ! G1 phase GO:0051318 44 22 0,000 0,04955755 0,06914283 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04955755 0,06910336 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04955755 0,06906394 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,04955755 0,06902457 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04955755 0,06898524 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04955755 0,06894595 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04955755 0,06890671 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04955755 0,06886751 ! sarcomere organization GO:0045214 32 22 0,000 0,04955755 0,06882836 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04955755 0,06878926 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04955755 0,06875019 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04955755 0,06871117 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04955755 0,0686722 ! gut development GO:0048565 44 22 0,000 0,04955755 0,06863327 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04955755 0,06859439 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04955755 0,06855554 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04955755 0,06851675 ! protein stabilization GO:0050821 41 22 0,000 0,04955755 0,06847799 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,05175158 0,07146925 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05175158 0,07142887 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,05175158 0,07138854 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05175158 0,07134825 ! gluconeogenesis GO:0006094 38 23 0,000 0,05175158 0,07130801 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05175158 0,07126781 ! viral genome replication GO:0019079 44 23 0,000 0,05175158 0,07122766 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05175158 0,07118756 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05175158 0,0711475 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05175158 0,07110748 ! regeneration GO:0031099 42 23 0,000 0,05175158 0,07106751 ! axis specification GO:0009798 43 23 0,000 0,05175158 0,07102759 ! visual behavior GO:0007632 46 23 0,000 0,05175158 0,0709877 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,05175158 0,07094787 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05175158 0,07090808 ! response to ethanol GO:0045471 47 23 0,000 0,05175158 0,07086833 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05175158 0,07082863 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,05175158 0,07078897 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05175158 0,07074936 ! peroxisome organization GO:0007031 43 23 0,000 0,05175158 0,07070979 ! lysosome organization GO:0007040 47 23 0,000 0,05175158 0,07067026 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05175158 0,07063078 ! vesicle targeting GO:0006903 49 23 0,000 0,05175158 0,07059135 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,05175158 0,07055195 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05175158 0,07051261 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05175158 0,0704733 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05175158 0,07043404 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05175158 0,07039482 ! DNA modification GO:0006304 36 23 0,000 0,05175158 0,07035565 ! fatty acid transport GO:0015908 47 23 0,000 0,05175158 0,07031652 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05175158 0,07027743 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05175158 0,07023839 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05175158 0,07019939 ! hormone transport GO:0009914 41 23 0,000 0,05175158 0,07016043 ! cell-cell recognition GO:0009988 28 23 0,000 0,05175158 0,07012152 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05175158 0,07008265 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05175158 0,07004382 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05175158 0,07000504 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0539406 0,07292578 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0539406 0,07288545 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0539406 0,07284516 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0539406 0,07280491 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0539406 0,07276471 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0539406 0,07272455 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0539406 0,07268444 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0539406 0,07264437 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0539406 0,07260435 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0539406 0,07256437 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0539406 0,07252443 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0539406 0,07248454 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0539406 0,07244469 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0539406 0,07240488 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0539406 0,07236512 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0539406 0,07232541 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0539406 0,07228573 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0539406 0,0722461 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0539406 0,07220652 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0539406 0,07216697 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0539406 0,07212747 ! pallium development GO:0021543 56 24 0,000 0,0539406 0,07208801 ! oogenesis GO:0048477 44 24 0,000 0,0539406 0,0720486 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0539406 0,07200923 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0539406 0,0719699 ! platelet activation GO:0030168 41 24 0,000 0,0539406 0,07193062 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0539406 0,07189138 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0539406 0,07185218 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0539406 0,07181302 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0539406 0,07177391 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0539406 0,07173483 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0539406 0,07169581 ! regulation of amine transport GO:0051952 41 24 0,000 0,0539406 0,07165682 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,05612464 0,07451765 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,05612464 0,07447718 ! leukocyte adhesion GO:0007159 55 25 0,000 0,05612464 0,07443675 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,05612464 0,07439636 ! phototransduction GO:0007602 37 25 0,000 0,05612464 0,07435601 ! keratinization GO:0031424 37 25 0,000 0,05612464 0,07431571 ! vacuole organization GO:0007033 49 25 0,000 0,05612464 0,07427545 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,05612464 0,07423524 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,05612464 0,07419507 ! receptor metabolic process GO:0043112 53 25 0,000 0,05612464 0,07415494 ! chromosome condensation GO:0030261 48 25 0,000 0,05612464 0,07411486 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,05612464 0,07407482 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,05612464 0,07403482 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,05612464 0,07399486 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,05612464 0,07395495 ! immunoglobulin production GO:0002377 62 25 0,000 0,05612464 0,07391509 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,05612464 0,07387526 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,05612464 0,07383548 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,05612464 0,07379574 ! liver development GO:0001889 55 25 0,000 0,05612464 0,07375604 ! protein tetramerization GO:0051262 57 25 0,000 0,05612464 0,07371639 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05830369 0,0765373 ! myelination GO:0042552 50 26 0,000 0,05830369 0,07649619 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05830369 0,07645513 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05830369 0,07641412 ! molting cycle process GO:0022404 52 26 0,000 0,05830369 0,07637314 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05830369 0,07633221 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05830369 0,07629133 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05830369 0,07625049 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05830369 0,07620969 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05830369 0,07616894 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05830369 0,07612823 ! digestive system process GO:0022600 49 26 0,000 0,05830369 0,07608756 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05830369 0,07604694 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05830369 0,07600636 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,05830369 0,07596582 ! neural crest cell development GO:0014032 59 26 0,000 0,05830369 0,07592533 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05830369 0,07588488 ! negative regulation of cell development GO:0010721 83 26 0,000 0,05830369 0,07584447 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05830369 0,0758041 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05830369 0,07576378 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05830369 0,0757235 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05830369 0,07568327 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05830369 0,07564308 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05830369 0,07560292 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,05830369 0,07556282 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05830369 0,07552275 ! blastocyst development GO:0001824 50 26 0,000 0,05830369 0,07548273 ! telomere organization GO:0032200 46 26 0,000 0,05830369 0,07544275 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05830369 0,07540281 ! neural tube closure GO:0001843 58 26 0,000 0,05830369 0,07536292 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05830369 0,07532306 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05830369 0,07528325 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05830369 0,07524348 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,06047777 0,07800802 ! embryonic pattern specification GO:0009880 49 27 0,000 0,06047777 0,07796686 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,06047777 0,07792574 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,06047777 0,07788466 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,06047777 0,07784362 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,06047777 0,07780263 ! iron ion transport GO:0006826 65 27 0,000 0,06047777 0,07776168 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,06047777 0,07772078 ! superoxide metabolic process GO:0006801 41 27 0,000 0,06047777 0,07767991 ! tube lumen formation GO:0035148 59 27 0,000 0,06047777 0,07763909 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,06047777 0,07759832 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,06047777 0,07755758 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,06047777 0,07751689 ! response to starvation GO:0042594 47 27 0,000 0,06047777 0,07747624 ! response to toxin GO:0009636 49 27 0,000 0,06047777 0,07743564 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,06047777 0,07739507 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,06047777 0,07735455 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,06047777 0,07731407 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,06047777 0,07727364 ! leukocyte proliferation GO:0070661 59 27 0,000 0,06047777 0,07723324 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,06047777 0,07719289 ! neuron fate commitment GO:0048663 52 28 0,000 0,0626469 0,07991978 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,0626469 0,07987806 ! circadian rhythm GO:0007623 56 28 0,000 0,0626469 0,0798364 ! dendrite development GO:0016358 67 28 0,000 0,0626469 0,07979477 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,0626469 0,07975319 ! fat cell differentiation GO:0045444 57 28 0,000 0,0626469 0,07971165 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,0626469 0,07967016 ! sperm motility GO:0030317 37 28 0,000 0,0626469 0,0796287 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,0626469 0,0795873 ! base-excision repair GO:0006284 41 28 0,000 0,0626469 0,07954593 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,0626469 0,07950461 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,0626469 0,07946333 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,0626469 0,07942209 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,0626469 0,0793809 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,0626469 0,07933975 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,0626469 0,07929864 ! glutathione metabolic process GO:0006749 42 28 0,000 0,0626469 0,07925757 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,0626469 0,07921655 ! lipid oxidation GO:0034440 48 28 0,000 0,0626469 0,07917557 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,0626469 0,07913463 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,0626469 0,07909373 ! translational initiation GO:0006413 66 29 0,000 0,06481108 0,08178381 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,06481108 0,08174159 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,06481108 0,08169941 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,06481108 0,08165728 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,06481108 0,08161518 ! autophagy GO:0006914 47 29 0,000 0,06481108 0,08157314 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,06481108 0,08153113 ! primary neural tube formation GO:0014020 61 29 0,000 0,06481108 0,08148917 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,06481108 0,08144725 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,06481108 0,08140538 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06481108 0,08136354 ! synaptogenesis GO:0007416 46 29 0,000 0,06481108 0,08132176 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,06481108 0,08128001 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06481108 0,08123831 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06481108 0,08119664 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06481108 0,08115503 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06697032 0,08381582 ! phenol metabolic process GO:0018958 56 30 0,000 0,06697032 0,08377291 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06697032 0,08373003 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06697032 0,08368721 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06697032 0,08364442 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06697032 0,08360168 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06697032 0,08355898 ! acute-phase response GO:0006953 50 30 0,000 0,06697032 0,08351633 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06697032 0,08347372 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06697032 0,08343115 ! myofibril assembly GO:0030239 50 30 0,000 0,06697032 0,08338863 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,06697032 0,08334615 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06697032 0,08330371 ! cell fate determination GO:0001709 64 30 0,000 0,06697032 0,08326132 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06697032 0,08321897 ! phospholipid transport GO:0015914 65 30 0,000 0,06697032 0,08317666 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06697032 0,08313439 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06697032 0,08309217 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06697032 0,08304999 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06697032 0,08300786 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06697032 0,08296576 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06912464 0,08559122 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06912464 0,08554786 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06912464 0,08550455 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06912464 0,08546128 ! cell junction assembly GO:0034329 85 31 0,000 0,06912464 0,08541805 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06912464 0,08537487 ! ovulation cycle process GO:0022602 55 31 0,000 0,06912464 0,08533173 ! peptide transport GO:0015833 60 31 0,000 0,06912464 0,08528863 ! male gonad development GO:0008584 56 31 0,000 0,06912464 0,08524557 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06912464 0,08520257 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06912464 0,0851596 ! detection of light stimulus GO:0009583 44 31 0,000 0,06912464 0,08511668 ! natural killer cell activation GO:0030101 50 31 0,000 0,06912464 0,0850738 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06912464 0,08503096 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06912464 0,08498817 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06912464 0,08494541 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06912464 0,08490271 ! eye morphogenesis GO:0048592 65 31 0,000 0,06912464 0,08486004 ! response to heat GO:0009408 54 31 0,000 0,06912464 0,08481742 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06912464 0,08477484 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,07127404 0,08736702 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,07127404 0,08732321 ! collagen metabolic process GO:0032963 49 32 0,000 0,07127404 0,08727944 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,07127404 0,08723571 ! spindle organization GO:0007051 50 32 0,000 0,07127404 0,08719203 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,07127404 0,08714839 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,07127404 0,08710479 ! metanephros development GO:0001656 81 32 0,000 0,07127404 0,08706124 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,07127404 0,08701773 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,07127404 0,08697426 ! muscle cell development GO:0055001 52 32 0,000 0,07127404 0,08693084 ! mesoderm formation GO:0001707 73 32 0,000 0,07127404 0,08688746 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,07127404 0,08684413 ! ovulation cycle GO:0042698 57 32 0,000 0,07127404 0,08680084 ! peripheral nervous system development GO:0007422 68 32 0,000 0,07127404 0,08675759 ! BMP signaling pathway GO:0030509 71 32 0,000 0,07127404 0,08671438 ! hindbrain development GO:0030902 65 32 0,000 0,07127404 0,08667122 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,07127404 0,0866281 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,07127404 0,08658502 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,07127404 0,08654199 ! gene silencing GO:0016458 71 32 0,000 0,07127404 0,086499 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,07341854 0,08905735 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,07341854 0,08901315 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,07341854 0,088969 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,07341854 0,08892489 ! response to ionizing radiation GO:0010212 74 33 0,000 0,07341854 0,08888082 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,07341854 0,0888368 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,07341854 0,08879282 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,07341854 0,08874888 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,07341854 0,08870499 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,07341854 0,08866114 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,07341854 0,08861734 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,07341854 0,08857358 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,07555815 0,09110985 ! glial cell differentiation GO:0010001 67 34 0,000 0,07555815 0,0910649 ! post-embryonic development GO:0009791 76 34 0,000 0,07555815 0,09102 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,07555815 0,09097514 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,07555815 0,09093033 ! spliceosome assembly GO:0000245 75 34 0,000 0,07555815 0,09088555 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,07555815 0,09084083 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,07555815 0,09079614 ! formation of primary germ layer GO:0001704 76 34 0,000 0,07555815 0,0907515 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,07555815 0,09070691 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,07769288 0,09322382 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,07769288 0,09317806 ! negative regulation of secretion GO:0051048 68 35 0,000 0,07769288 0,09313234 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,07769288 0,09308666 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,07769288 0,09304103 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,07769288 0,09299545 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,07769288 0,0929499 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,07769288 0,09290441 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,07769288 0,09285895 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,07769288 0,09281355 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,07769288 0,09276818 ! ceramide metabolic process GO:0006672 72 35 0,000 0,07769288 0,09272286 ! telencephalon development GO:0021537 81 35 0,000 0,07769288 0,09267759 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,07769288 0,09263236 ! placenta development GO:0001890 53 35 0,000 0,07769288 0,09258717 ! vesicle localization GO:0051648 70 35 0,000 0,07769288 0,09254203 ! regulation of muscle development GO:0048634 82 36 0,000 0,07982274 0,09503263 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07982274 0,09498634 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07982274 0,09494009 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07982274 0,09489389 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07982274 0,09484774 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07982274 0,09480163 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07982274 0,09475556 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07982274 0,09470954 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07982274 0,09466357 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,07982274 0,09461764 ! aerobic respiration GO:0009060 56 36 0,000 0,07982274 0,09457175 ! cytokine production GO:0001816 68 36 0,000 0,07982274 0,09452591 ! embryonic organ development GO:0048568 67 36 0,000 0,07982274 0,09448011 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07982274 0,09443436 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07982274 0,09438865 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,08194774 0,09685454 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,08194774 0,0968077 ! sister chromatid segregation GO:0000819 65 37 0,000 0,08194774 0,09676091 ! odontogenesis GO:0042476 74 37 0,000 0,08194774 0,09671417 ! actomyosin structure organization GO:0031032 68 37 0,000 0,08194774 0,09666747 ! cell junction organization GO:0034330 96 37 0,000 0,08194774 0,09662081 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,08194774 0,09657421 ! female gonad development GO:0008585 71 37 0,000 0,08194774 0,09652764 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,08194774 0,09648112 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,08194774 0,09643465 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,08406789 0,09888198 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,08406789 0,09883439 ! meiosis I GO:0007127 74 38 0,000 0,08406789 0,09878685 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,08406789 0,09873936 ! organic anion transport GO:0015711 82 38 0,000 0,08406789 0,09869191 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,08406789 0,09864451 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,08406789 0,09859715 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,08406789 0,09854984 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,08406789 0,09850257 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,08406789 0,09845535 ! regulation of protein stability GO:0031647 77 38 0,000 0,08406789 0,09840818 ! spermatid development GO:0007286 69 38 0,000 0,08406789 0,09836105 ! glycogen metabolic process GO:0005977 63 38 0,000 0,08406789 0,09831396 ! pigment metabolic process GO:0042440 87 38 0,000 0,08406789 0,09826692 ! neural tube formation GO:0001841 79 38 0,000 0,08406789 0,09821992 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,08618321 0,1006432 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08618321 0,10059512 ! negative regulation of binding GO:0051100 71 39 0,000 0,08618321 0,10054708 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,08618321 0,10049908 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,08618321 0,10045114 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,08618321 0,10040323 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08618321 0,10035538 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,08618321 0,10030757 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08618321 0,1002598 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,08618321 0,10021208 ! glucan metabolic process GO:0044042 64 39 0,000 0,08618321 0,10016441 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,0882937 0,10256848 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,0882937 0,10251973 ! learning GO:0007612 82 40 0,000 0,0882937 0,10247103 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,0882937 0,10242237 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,0882937 0,10237376 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,0882937 0,10232519 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,0882937 0,10227668 ! RNA export from nucleus GO:0006405 61 41 0,000 0,09039938 0,1046662 ! mRNA catabolic process GO:0006402 79 41 0,000 0,09039938 0,10461662 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,09039938 0,10456708 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,09039938 0,10451759 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,09039938 0,10446815 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,09039938 0,10441876 ! gliogenesis GO:0042063 91 41 0,000 0,09039938 0,10436941 ! feeding behavior GO:0007631 69 41 0,000 0,09039938 0,10432011 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,09039938 0,10427086 ! mesenchymal cell development GO:0014031 94 41 0,000 0,09039938 0,10422165 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 95 41 0,000 0,09039938 0,10417249 ! spermatid differentiation GO:0048515 73 41 0,000 0,09039938 0,10412337 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,09039938 0,10407431 ! RNA modification GO:0009451 64 41 0,000 0,09039938 0,10402528 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,09250025 0,10639271 ! ear morphogenesis GO:0042471 64 42 0,000 0,09250025 0,10634264 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,09250025 0,10629262 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,09250025 0,10624265 ! T cell differentiation GO:0030217 93 42 0,000 0,09250025 0,10619272 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,09250025 0,10614284 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,09250025 0,10609301 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,09250025 0,10604322 ! regulation of protein secretion GO:0050708 77 42 0,000 0,09250025 0,10599348 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,09250025 0,10594379 ! cytokinesis GO:0000910 84 42 0,000 0,09250025 0,10589415 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,09250025 0,10584455 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,09459633 0,10819233 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,09459633 0,10814171 ! regulation of tube size GO:0035150 76 43 0,000 0,09459633 0,10809113 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,09459633 0,10804059 ! glucose transport GO:0015758 66 43 0,000 0,09459633 0,10799011 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,09459633 0,10793967 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,09459633 0,10788927 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,09459633 0,10783893 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,09459633 0,10778863 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,09459633 0,10773838 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,09459633 0,10768818 ! neuron migration GO:0001764 85 43 0,000 0,09459633 0,10763802 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,09459633 0,10758791 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,09668762 0,10991525 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,09668762 0,10986412 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,09668762 0,10981305 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,09668762 0,10976202 ! hexose transport GO:0008645 68 44 0,000 0,09668762 0,10971104 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,09668762 0,1096601 ! striated muscle contraction GO:0006941 85 44 0,000 0,09668762 0,10960922 ! phagocytosis GO:0006909 105 44 0,000 0,09668762 0,10955838 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,09668762 0,10950759 ! double-strand break repair GO:0006302 85 44 0,000 0,09668762 0,10945684 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,09877415 0,11176713 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,09877415 0,11171539 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,09877415 0,11166369 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,09877415 0,11161205 ! biopolymer methylation GO:0043414 91 45 0,000 0,09877415 0,11156044 ! B cell differentiation GO:0030183 124 45 0,000 0,09877415 0,11150889 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,09877415 0,11145739 ! female gamete generation GO:0007292 71 45 0,000 0,09877415 0,11140593 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,09877415 0,11135452 ! polyol metabolic process GO:0019751 77 45 0,000 0,09877415 0,11130316 ! developmental growth GO:0048589 88 45 0,000 0,09877415 0,11125184 ! maintenance of location in cell GO:0051651 101 45 0,000 0,09877415 0,11120057 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,10085591 0,11349193 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,10085591 0,11343968 ! glycolysis GO:0006096 71 46 0,000 0,10085591 0,11338748 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,10085591 0,11333532 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,10085591 0,11328321 ! leukocyte migration GO:0050900 75 46 0,000 0,10085591 0,11323115 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,10085591 0,11317914 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,10085591 0,11312718 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,10085591 0,11307526 ! pigmentation GO:0043473 103 46 0,000 0,10085591 0,11302339 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,10085591 0,11297157 ! neural tube development GO:0021915 91 47 0,000 0,10293292 0,11524525 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,10293292 0,11519246 ! positive regulation of defense response GO:0031349 88 48 0,000 0,1050052 0,11745774 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,1050052 0,11740398 ! mitochondrial transport GO:0006839 94 48 0,000 0,1050052 0,11735027 ! cellular component disassembly GO:0022411 89 48 0,000 0,1050052 0,11729662 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,1050052 0,11724301 ! endosome transport GO:0016197 127 48 0,000 0,1050052 0,11718945 ! male sex differentiation GO:0046661 93 48 0,000 0,1050052 0,11713594 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,1050052 0,11708247 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,1050052 0,11702906 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,1050052 0,11697569 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,1050052 0,11692238 ! methylation GO:0032259 97 48 0,000 0,1050052 0,11686911 ! response to calcium ion GO:0051592 94 49 0,000 0,10707274 0,11911599 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,10707274 0,11906177 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,10707274 0,1190076 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,10707274 0,11895348 ! regulation of action potential GO:0001508 102 50 0,000 0,10913557 0,12119009 ! regulation of ion transport GO:0043269 86 50 0,000 0,10913557 0,12113503 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,10913557 0,12108002 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,10913557 0,12102505 ! activation of caspase activity GO:0006919 95 50 0,000 0,10913557 0,12097014 ! regulation of ossification GO:0030278 123 50 0,000 0,10913557 0,12091528 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,10913557 0,12086047 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,10913557 0,12080571 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,10913557 0,12075099 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,10913557 0,12069633 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,10913557 0,12064172 ! peptide metabolic process GO:0006518 80 51 0,000 0,11119369 0,12286123 ! response to temperature stimulus GO:0009266 84 51 0,000 0,11119369 0,12280569 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,11119369 0,12275019 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,11119369 0,12269475 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,11324711 0,12490415 ! Notch signaling pathway GO:0007219 111 52 0,000 0,11324711 0,12484779 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,11324711 0,12479147 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,11324711 0,12473521 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,11324711 0,124679 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,11324711 0,12462283 ! excretion GO:0007588 87 52 0,000 0,11324711 0,12456672 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,11324711 0,12451066 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,11324711 0,12445465 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,11324711 0,12439869 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,11324711 0,12434278 ! amino acid activation GO:0043038 98 52 0,000 0,11324711 0,12428692 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,11529585 0,12647856 ! positive regulation of growth GO:0045927 96 53 0,000 0,11529585 0,12642179 ! inner ear development GO:0048839 89 53 0,000 0,11529585 0,12636508 ! chromatin remodeling GO:0006338 122 53 0,000 0,11529585 0,12630841 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,11529585 0,12625179 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,11529585 0,12619523 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,11529585 0,12613872 ! cartilage development GO:0051216 99 53 0,000 0,11529585 0,12608225 ! synapse organization GO:0050808 102 53 0,000 0,11529585 0,12602584 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,11733991 0,12820277 ! regulation of translational initiation GO:0006446 87 54 0,000 0,11733991 0,12814546 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,11733991 0,1280882 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,11733991 0,12803099 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,11733991 0,12797384 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,11733991 0,12791673 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,11733991 0,12785968 ! RNA catabolic process GO:0006401 103 55 0,000 0,1193793 0,13002391 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,1193793 0,12996597 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,1193793 0,12990808 ! cell recognition GO:0008037 98 55 0,000 0,1193793 0,12985024 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,1193793 0,12979245 ! cell maturation GO:0048469 107 55 0,000 0,1193793 0,12973471 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,1193793 0,12967703 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,12141404 0,13182867 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,12141404 0,1317701 ! glucose catabolic process GO:0006007 88 56 0,000 0,12141404 0,13171159 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,12141404 0,13165313 ! regulation of DNA replication GO:0006275 105 56 0,000 0,12141404 0,13159472 ! RNA elongation GO:0006354 90 56 0,000 0,12141404 0,13153637 ! chloride transport GO:0006821 102 57 0,000 0,12344414 0,13367643 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,12344414 0,1336172 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,12344414 0,13355803 ! heart morphogenesis GO:0003007 105 57 0,000 0,12344414 0,13349891 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,12344414 0,13343984 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,12344414 0,13338082 ! regulation of actin filament length GO:0030832 118 58 0,000 0,1254696 0,13550939 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,1254696 0,13544951 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,1254696 0,13538968 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,1254696 0,1353299 ! aging GO:0007568 112 58 0,000 0,1254696 0,13527018 ! gastrulation GO:0007369 122 58 0,000 0,1254696 0,13521051 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,1254696 0,1351509 ! maintenance of location GO:0051235 124 58 0,000 0,1254696 0,13509133 ! nuclear export GO:0051168 110 59 0,000 0,12749044 0,13720667 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,12950667 0,13931518 ! DNA catabolic process GO:0006308 94 60 0,000 0,12950667 0,13925387 ! regulation of endocytosis GO:0030100 104 60 0,000 0,12950667 0,1391926 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,12950667 0,13913139 ! kidney development GO:0001822 133 60 0,000 0,12950667 0,13907023 ! positive regulation of secretion GO:0051047 110 61 0,000 0,13151829 0,14116836 ! regulation of cellular component size GO:0032535 125 61 0,000 0,13151829 0,14110636 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,13151829 0,14104442 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,13151829 0,14098253 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,13151829 0,14092069 ! regulation of heart contraction GO:0008016 123 61 0,000 0,13151829 0,14085891 ! camera-type eye development GO:0043010 126 61 0,000 0,13151829 0,14079719 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,13151829 0,14073551 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,13352532 0,14282065 ! tRNA processing GO:0008033 102 62 0,000 0,13352532 0,14275814 ! regulation of mitosis GO:0007088 112 63 0,000 0,13552777 0,14483567 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,13552777 0,14477234 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,13552777 0,14470907 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,13552777 0,14464585 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,13752565 0,14671404 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,13752565 0,14665 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,13951897 0,14871066 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,13951897 0,14864581 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,13951897 0,14858101 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,13951897 0,14851627 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,13951897 0,14845158 ! ear development GO:0043583 114 66 0,000 0,14150773 0,15050213 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,14150773 0,15043664 ! gonad development GO:0008406 115 66 0,000 0,14150773 0,1503712 ! activation of MAPK activity GO:0000187 124 67 0,000 0,14349196 0,15241342 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,14349196 0,15234718 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,14349196 0,152281 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,14349196 0,15221487 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,14349196 0,15214881 ! secondary metabolic process GO:0019748 125 67 0,000 0,14349196 0,1520828 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,14547165 0,15411416 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,14547165 0,15404736 ! hexose catabolic process GO:0019320 113 68 0,000 0,14547165 0,15398061 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,14547165 0,15391392 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,14547165 0,15384729 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,14547165 0,15378072 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,14547165 0,15371421 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,14744683 0,15573394 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,14744683 0,15566664 ! urogenital system development GO:0001655 149 69 0,000 0,14744683 0,1555994 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,14744683 0,15553221 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,14744683 0,15546509 ! developmental maturation GO:0021700 128 69 0,000 0,14744683 0,15539802 ! single fertilization GO:0007338 83 69 0,000 0,14744683 0,15533101 ! cell redox homeostasis GO:0045454 114 70 0,000 0,1494175 0,1573392 ! activation of immune response GO:0002253 120 70 0,000 0,1494175 0,15727141 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,1494175 0,15720368 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,15138366 0,15920374 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,15138366 0,15913523 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,15138366 0,15906679 ! appendage morphogenesis GO:0035107 150 72 0,000 0,15334534 0,16105875 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,15334534 0,16098954 ! actin filament organization GO:0007015 167 72 0,000 0,15334534 0,16092039 ! B cell activation GO:0042113 179 72 0,000 0,15334534 0,16085129 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,15334534 0,16078226 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,15334534 0,16071328 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,15334534 0,16064436 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,15334534 0,16057551 ! appendage development GO:0048736 151 73 0,000 0,15530253 0,16255531 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,15530253 0,16248569 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,15530253 0,16241613 ! regulation of immune effector process GO:0002697 156 73 0,000 0,15530253 0,16234664 ! acute inflammatory response GO:0002526 118 74 0,000 0,15725526 0,16431762 ! amino acid transport GO:0006865 148 74 0,000 0,15725526 0,16424737 ! regulation of caspase activity GO:0043281 136 74 0,000 0,15725526 0,16417718 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,15725526 0,16410705 ! transition metal ion transport GO:0000041 143 75 0,000 0,15920353 0,16606927 ! reproductive structure development GO:0048608 131 75 0,000 0,15920353 0,16599839 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,15920353 0,16592757 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,15920353 0,16585681 ! eye development GO:0001654 155 75 0,000 0,15920353 0,16578611 ! rhythmic process GO:0048511 142 75 0,000 0,15920353 0,16571548 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,16114735 0,16766736 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,16114735 0,16759599 ! learning or memory GO:0007611 161 76 0,000 0,16114735 0,16752467 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,16114735 0,16745341 ! regulation of blood pressure GO:0008217 134 76 0,000 0,16114735 0,16738222 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,16114735 0,16731108 ! amine catabolic process GO:0009310 136 77 0,000 0,16308673 0,16925271 ! neurotransmitter transport GO:0006836 142 77 0,000 0,16308673 0,16918084 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,16308673 0,16910903 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,16308673 0,16903728 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,16308673 0,1689656 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,16308673 0,16889397 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,16308673 0,16882241 ! regulation of catabolic process GO:0009894 173 77 0,000 0,16308673 0,1687509 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,16502168 0,17068076 ! antigen processing and presentation GO:0019882 117 78 0,000 0,16502168 0,17060853 ! fertilization GO:0009566 99 78 0,000 0,16502168 0,17053636 ! blood coagulation GO:0007596 151 79 0,000 0,16695221 0,17245846 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,16695221 0,17238557 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,16695221 0,17231274 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,16695221 0,17223997 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,16695221 0,17216726 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,16695221 0,17209462 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,16887833 0,17400665 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,16887833 0,17393329 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,16887833 0,17385999 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,16887833 0,17378676 ! muscle cell differentiation GO:0042692 178 81 0,000 0,17080005 0,17569033 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,17080005 0,17561639 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,17271739 0,17751307 ! protein import into nucleus GO:0006606 174 82 0,000 0,17271739 0,17743843 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,17463034 0,17932826 ! exocytosis GO:0006887 153 83 0,000 0,17463034 0,17925291 ! response to drug GO:0042493 149 83 0,000 0,17463034 0,17917762 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,17463034 0,1791024 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,17463034 0,17902725 ! nuclear import GO:0051170 177 83 0,000 0,17463034 0,17895215 ! inorganic anion transport GO:0015698 156 83 0,000 0,17463034 0,17887712 ! response to metal ion GO:0010038 158 84 0,000 0,17653893 0,18075633 ! T cell activation GO:0042110 189 84 0,000 0,17653893 0,1806806 ! response to nutrient GO:0007584 135 84 0,000 0,17653893 0,18060494 ! digestion GO:0007586 130 84 0,000 0,17653893 0,18052934 ! regulation of ligase activity GO:0051340 147 84 0,000 0,17653893 0,18045381 ! hemostasis GO:0007599 165 85 0,000 0,17844315 0,18232397 ! negative regulation of transport GO:0051051 164 85 0,000 0,17844315 0,18224775 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,17844315 0,18217159 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,17844315 0,1820955 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,17844315 0,18201946 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,17844315 0,1819435 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,18034303 0,18380393 ! regulation of lyase activity GO:0051339 169 86 0,000 0,18034303 0,18372728 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,18223856 0,18558099 ! mitochondrion organization GO:0007005 159 87 0,000 0,18223856 0,18550367 ! alcohol catabolic process GO:0046164 142 87 0,000 0,18223856 0,18542641 ! nucleosome assembly GO:0006334 126 87 0,000 0,18223856 0,18534921 ! regulation of protein transport GO:0051223 165 87 0,000 0,18223856 0,18527208 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,18412977 0,1871169 ! amine biosynthetic process GO:0009309 146 88 0,000 0,18412977 0,18703909 ! sensory perception of smell GO:0007608 117 88 0,000 0,18412977 0,18696135 ! chromatin assembly GO:0031497 128 88 0,000 0,18412977 0,18688368 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,18412977 0,18680607 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,18601665 0,18864204 ! tube morphogenesis GO:0035239 194 89 0,000 0,18601665 0,18856376 ! cellular defense response GO:0006968 123 89 0,000 0,18601665 0,18848556 ! protein localization in nucleus GO:0034504 192 89 0,000 0,18601665 0,18840741 ! response to inorganic substance GO:0010035 173 90 0,000 0,18789922 0,19023531 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,18789922 0,1901565 ! response to unfolded protein GO:0006986 139 90 0,000 0,18789922 0,19007776 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,18789922 0,18999909 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,18977749 0,19181896 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,18977749 0,19173963 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,19165148 0,19355294 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,19352117 0,19536043 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,19352117 0,19527973 ! vitamin metabolic process GO:0006766 153 93 0,000 0,19352117 0,1951991 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,1953866 0,19699937 ! female pregnancy GO:0007565 166 94 0,000 0,1953866 0,1969181 ! sterol metabolic process GO:0016125 166 94 0,000 0,1953866 0,19683689 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,1953866 0,19675576 ! regulation of defense response GO:0031347 171 95 0,000 0,19724777 0,19854812 ! nucleosome organization GO:0034728 143 95 0,000 0,19724777 0,19846635 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,19724777 0,19838464 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,19724777 0,198303 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,19724777 0,19822143 ! sex differentiation GO:0007548 171 96 0,000 0,19910468 0,20000524 ! response to protein stimulus GO:0051789 158 96 0,000 0,19910468 0,19992303 ! regulation of T cell activation GO:0050863 175 96 0,000 0,19910468 0,19984089 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,20095735 0,20161758 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,20095735 0,20153481 ! transcription initiation GO:0006352 171 97 0,000 0,20095735 0,20145211 ! regulation of protein localization GO:0032880 188 97 0,000 0,20095735 0,20136948 ! forebrain development GO:0030900 210 98 0,000 0,20280578 0,20313839 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,20280578 0,20305514 ! mRNA transport GO:0051028 185 100 0,000 0,20648999 0,20665918 ! positive regulation of immune response GO:0050778 175 100 0,000 0,20648999 0,20657455 ! hormone metabolic process GO:0042445 171 100 0,000 0,20648999 0,20648999