pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1180-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 156 86 7,000 2,928E-08 6,735E-05 ! interphase GO:0051325 159 88 7,000 3,515E-08 4,042E-05 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 5,000 1,456E-07 1,117E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 4,148E-07 2,385E-04 ! G1 phase GO:0051318 27 16 3,000 1,671E-06 7,688E-04 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 7,888E-06 3,024E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 2,000 9,664E-06 3,175E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 2,000 9,664E-06 2,778E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 1,117E-05 2,855E-03 GO:0045936|negative regulation of phosphate metabolic process, ! detection of bacterium GO:0016045 10 10 2,000 2,054E-05 4,724E-03 ! N-terminal protein amino acid modification GO:0031365 18 13 2,000 4,835E-05 0,01010945 ! G1 phase of mitotic cell cycle GO:0000080 23 14 2,000 6,128E-05 0,01174589 ! epithelial to mesenchymal transition GO:0001837 22 14 2,000 6,128E-05 0,01084236 ! gliogenesis GO:0042063 71 38 3,000 6,161E-05 0,01012118 ! negative regulation of cell cycle process GO:0010948 24 15 2,000 7,629E-05 0,01169763 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 7,629E-05 0,01096652 ! epithelial cell differentiation GO:0030855 55 41 3,000 8,343E-05 0,01128746 ! detection of biotic stimulus GO:0009595 19 16 2,000 9,351E-05 0,01194828 ! peptidyl-serine modification GO:0018209 27 17 2,000 1,131E-04 0,01368857 ! response to UV GO:0009411 75 46 3,000 1,316E-04 0,01512875 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 1,598E-04 0,01750387 ! peptidyl-amino acid modification GO:0018193 147 93 4,000 1,843E-04 0,01927241 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 2,176E-04 0,02175614 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 2,509E-04 0,02404265 ! blastocyst development GO:0001824 37 22 2,000 2,509E-04 0,02308094 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 2,873E-04 0,02541753 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 3,036E-04 0,02586517 ! glial cell fate commitment GO:0021781 12 5 1,000 3,14E-04 0,02578973 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 1,000 3,14E-04 0,02490043 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 3,14E-04 0,02407042 ! microvillus organization GO:0032528 7 5 1,000 3,14E-04 0,02329395 GO:0030033|microvillus assembly, ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 3,14E-04 0,02256601 ! monocyte differentiation GO:0030224 8 5 1,000 3,14E-04 0,0218822 ! muscle cell proliferation GO:0033002 8 5 1,000 3,14E-04 0,0212386 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 3,14E-04 0,02063178 ! receptor biosynthetic process GO:0032800 6 5 1,000 3,14E-04 0,02005868 ! negative regulation of kinase activity GO:0033673 100 58 3,000 3,247E-04 0,0201852 ! fat cell differentiation GO:0045444 37 24 2,000 3,27E-04 0,01979387 ! regulation of chromosome organization GO:0033044 35 25 2,000 3,701E-04 0,02182646 ! negative regulation of transferase activity GO:0051348 105 61 3,000 3,943E-04 0,02266984 ! negative regulation of cell growth GO:0030308 106 62 3,000 4,196E-04 0,02354024 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 4,461E-04 0,02443188 ! prostate gland development GO:0030850 9 6 1,000 4,692E-04 0,0250969 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 4,692E-04 0,02452651 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 4,692E-04 0,02398148 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 1,000 4,692E-04 0,02346014 ! ER overload response GO:0006983 7 6 1,000 4,692E-04 0,02296099 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 4,692E-04 0,02248264 ! blastocyst growth GO:0001832 15 6 1,000 4,692E-04 0,02202381 ! positive regulation of smooth muscle contraction GO:0045987 9 6 1,000 4,692E-04 0,02158333 ! negative regulation of cell size GO:0045792 108 64 3,000 4,738E-04 0,02136918 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 6,545E-04 0,02894718 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 6,545E-04 0,02840101 ! lipoprotein transport GO:0042953 9 7 1,000 6,545E-04 0,02787506 ! cardiac muscle cell differentiation GO:0055007 12 7 1,000 6,545E-04 0,02736824 ! regulation of fat cell differentiation GO:0045598 9 7 1,000 6,545E-04 0,02687953 ! peptidyl-threonine modification GO:0018210 18 7 1,000 6,545E-04 0,02640796 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 6,545E-04 0,02595265 ! steroid biosynthetic process GO:0006694 94 71 3,000 7,03E-04 0,02740617 ! glial cell differentiation GO:0010001 55 31 2,000 7,057E-04 0,0270523 ! negative regulation of organelle organization GO:0010639 115 72 3,000 7,412E-04 0,02794599 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 8,496E-04 0,03151716 ! negative regulation of growth GO:0045926 123 75 3,000 8,644E-04 0,03155709 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 8,694E-04 0,03124368 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 8,694E-04 0,03076301 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 8,694E-04 0,0302969 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 8,694E-04 0,02984471 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 8,694E-04 0,02940581 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 8,694E-04 0,02897964 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 8,694E-04 0,02856565 GO:0000076|DNA replication checkpoint, ! cellular response to insulin stimulus GO:0032869 52 34 2,000 9,28E-04 0,03006199 ! SMAD protein nuclear translocation GO:0007184 15 9 1,000 1,114E-03 0,0355753 ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 1,114E-03 0,03508797 ! positive regulation of muscle contraction GO:0045933 12 9 1,000 1,114E-03 0,0346138 ! regulation of DNA replication initiation GO:0030174 13 9 1,000 1,114E-03 0,03415229 ! blastocyst formation GO:0001825 12 9 1,000 1,114E-03 0,03370291 ! striated muscle cell differentiation GO:0051146 54 38 2,000 1,287E-03 0,03844276 ! mesenchymal cell development GO:0014031 64 38 2,000 1,287E-03 0,0379499 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 2,000 1,287E-03 0,03746953 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,387E-03 0,03987459 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,387E-03 0,03938231 ! melanocyte differentiation GO:0030318 15 10 1,000 1,387E-03 0,03890204 GO:0050931|pigment cell differentiation, ! alpha-beta T cell activation GO:0046631 16 10 1,000 1,387E-03 0,03843334 ! DNA methylation GO:0006306 15 10 1,000 1,387E-03 0,0379758 GO:0006305|DNA alkylation, ! cardiac cell differentiation GO:0035051 16 10 1,000 1,387E-03 0,03752902 ! cell cycle arrest GO:0007050 150 86 3,000 1,44E-03 0,03851882 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 1,495E-03 0,03952311 ! T cell proliferation GO:0042098 20 11 1,000 1,689E-03 0,04414175 ! oligodendrocyte differentiation GO:0048709 14 11 1,000 1,689E-03 0,04364577 ! chromatin silencing GO:0006342 19 11 1,000 1,689E-03 0,04316082 ! lysogeny GO:0030069 18 11 1,000 1,689E-03 0,04268652 GO:0019047|provirus integration, ! regulation of gene expression, epigenetic GO:0040029 72 42 2,000 1,723E-03 0,04307388 ! response to insulin stimulus GO:0032868 63 43 2,000 1,845E-03 0,04561957 ! heart looping GO:0001947 15 12 1,000 2,019E-03 0,04940627 ! histone acetylation GO:0016573 23 12 1,000 2,019E-03 0,04888621 ! peptidyl-lysine modification GO:0018205 18 12 1,000 2,019E-03 0,04837698 ! positive regulation of cell cycle GO:0045787 77 45 2,000 2,104E-03 0,04988196 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 2,158E-03 0,05065077 ! response to light stimulus GO:0009416 153 96 3,000 2,158E-03 0,05013915 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 1,000 2,378E-03 0,05468369 ! covalent chromatin modification GO:0016569 75 47 2,000 2,384E-03 0,05429742 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 2,000 2,384E-03 0,0537651 ! heart morphogenesis GO:0003007 65 48 2,000 2,533E-03 0,05656114 ! RNA elongation GO:0006354 62 49 2,000 2,687E-03 0,05942741 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,764E-03 0,06053592 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 1,000 2,764E-03 0,05996483 ! epidermis morphogenesis GO:0048730 29 14 1,000 2,764E-03 0,05940441 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,764E-03 0,05885437 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 2,764E-03 0,05831442 ! muscle maintenance GO:0046716 19 14 1,000 2,764E-03 0,05778429 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 3,177E-03 0,06583032 ! lipid phosphorylation GO:0046834 23 15 1,000 3,177E-03 0,06524255 ! regulation of neurotransmitter secretion GO:0046928 26 15 1,000 3,177E-03 0,06466518 ! regulation of muscle cell differentiation GO:0051147 24 15 1,000 3,177E-03 0,06409794 ! DNA integration GO:0015074 22 15 1,000 3,177E-03 0,06354057 ! dopamine metabolic process GO:0042417 30 15 1,000 3,177E-03 0,0629928 ! detection of external stimulus GO:0009581 66 54 2,000 3,545E-03 0,06968049 ! endothelial cell migration GO:0043542 22 16 1,000 3,618E-03 0,0705112 ! protein amino acid acetylation GO:0006473 28 16 1,000 3,618E-03 0,06991867 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,618E-03 0,06933602 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 4,085E-03 0,0776448 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 1,000 4,085E-03 0,07700836 ! long-chain fatty acid transport GO:0015909 24 17 1,000 4,085E-03 0,07638228 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 4,131E-03 0,07661551 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 4,338E-03 0,07982228 ! myeloid cell differentiation GO:0030099 85 59 2,000 4,552E-03 0,08309186 ! response to retinoic acid GO:0032526 25 18 1,000 4,578E-03 0,08291768 ! pigmentation during development GO:0048066 31 18 1,000 4,578E-03 0,08226989 ! somitogenesis GO:0001756 24 18 1,000 4,578E-03 0,08163214 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 4,578E-03 0,0810042 ! urogenital system development GO:0001655 101 61 2,000 4,999E-03 0,08776051 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 5,098E-03 0,08883476 ! response to vitamin A GO:0033189 26 19 1,000 5,098E-03 0,08816683 ! sex determination GO:0007530 29 19 1,000 5,098E-03 0,08750887 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 5,098E-03 0,08686066 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 5,098E-03 0,08622198 ! response to vitamin GO:0033273 29 20 1,000 5,644E-03 0,09475362 ! hindlimb morphogenesis GO:0035137 32 20 1,000 5,644E-03 0,094067 ! regulation of neurotransmitter transport GO:0051588 35 20 1,000 5,644E-03 0,09339026 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 5,644E-03 0,09272318 ! DNA modification GO:0006304 28 20 1,000 5,644E-03 0,09206557 ! positive regulation of B cell activation GO:0050871 31 20 1,000 5,644E-03 0,09141722 ! cell cycle checkpoint GO:0000075 108 64 2,000 5,716E-03 0,0919415 ! reproductive structure development GO:0048608 90 65 2,000 5,969E-03 0,09533237 ! myeloid leukocyte differentiation GO:0002573 33 21 1,000 6,215E-03 0,09858635 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 6,215E-03 0,0979111 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 1,000 6,215E-03 0,09724503 ! protein amino acid acylation GO:0043543 37 21 1,000 6,215E-03 0,09658797 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 6,215E-03 0,09593973 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 6,215E-03 0,09530013 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 1,000 6,215E-03 0,09466901 GO:0060415|muscle tissue morphogenesis, ! fatty acid transport GO:0015908 30 21 1,000 6,215E-03 0,09404618 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 6,215E-03 0,0934315 ! response to cytokine stimulus GO:0034097 47 21 1,000 6,215E-03 0,09282481 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 6,812E-03 0,10107626 ! vasculogenesis GO:0001570 33 22 1,000 6,812E-03 0,10042833 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 6,812E-03 0,09978866 GO:0010810|regulation of cell-substrate adhesion, ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 6,812E-03 0,09915709 ! barbed-end actin filament capping GO:0051016 33 22 1,000 6,812E-03 0,09853346 GO:0051693|actin filament capping, ! eye development GO:0001654 111 70 2,000 7,329E-03 0,10536096 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 2,000 7,329E-03 0,10470654 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 7,433E-03 0,10553061 ! negative regulation of DNA replication GO:0008156 35 23 1,000 7,433E-03 0,10488319 ! lymphocyte proliferation GO:0046651 36 23 1,000 7,433E-03 0,10424365 ! cell fate determination GO:0001709 45 23 1,000 7,433E-03 0,10361187 ! muscle cell differentiation GO:0042692 104 71 2,000 7,622E-03 0,10560326 ! initiation of viral infection GO:0019059 42 24 1,000 8,079E-03 0,11126801 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 8,079E-03 0,1106057 ! receptor metabolic process GO:0043112 37 24 1,000 8,079E-03 0,10995123 ! response to toxin GO:0009636 38 24 1,000 8,079E-03 0,10930446 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 8,079E-03 0,10866525 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 8,079E-03 0,10803348 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 8,54E-03 0,11353571 ! negative regulation of actin filament depolymerization GO:0030835 36 25 1,000 8,749E-03 0,11565255 ! negative regulation of actin filament polymerization GO:0030837 36 25 1,000 8,749E-03 0,11499168 ! male gonad development GO:0008584 33 25 1,000 8,749E-03 0,11433831 ! positive regulation of nuclear division GO:0051785 39 25 1,000 8,749E-03 0,11369234 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 1,000 8,749E-03 0,11305361 GO:0032943|mononuclear cell proliferation, ! response to nutrient GO:0007584 104 75 2,000 8,86E-03 0,11383935 ! negative regulation of protein modification process GO:0031400 50 26 1,000 9,444E-03 0,12067025 ! negative regulation of protein polymerization GO:0032272 38 26 1,000 9,444E-03 0,12000357 ! sex differentiation GO:0007548 105 77 2,000 9,52E-03 0,12030989 ! regulation of actin filament depolymerization GO:0030834 39 27 1,000 0,01016191 0,12771804 ! catechol metabolic process GO:0009712 43 27 1,000 0,01016191 0,12702392 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! natural killer cell activation GO:0030101 35 27 1,000 0,01016191 0,12633731 ! gene silencing GO:0016458 41 27 1,000 0,01016191 0,12565807 ! T cell activation GO:0042110 134 79 2,000 0,01020871 0,12556173 ! phenol metabolic process GO:0018958 44 28 1,000 0,01090355 0,13339444 ! negative regulation of protein complex assembly GO:0031333 42 28 1,000 0,01090355 0,13268865 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,01090355 0,13199029 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 0,01090355 0,13129924 ! placenta development GO:0001890 37 28 1,000 0,01090355 0,13061539 ! regulation of B cell activation GO:0050864 42 28 1,000 0,01090355 0,12993863 ! regulation of cell cycle process GO:0010564 122 81 2,000 0,01092552 0,1295293 ! detection of stimulus GO:0051606 108 82 2,000 0,01129458 0,13321808 ! rRNA metabolic process GO:0016072 107 85 2,000 0,01244469 0,14603459 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 2,000 0,01244469 0,1452933 ! spindle organization GO:0007051 37 30 1,000 0,01245611 0,14469218 ! hindbrain development GO:0030902 45 30 1,000 0,01245611 0,14396508 ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 0,01324741 0,15234521 ! segmentation GO:0035282 41 31 1,000 0,01326648 0,15180551 ! metanephros development GO:0001656 58 31 1,000 0,01326648 0,151054 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01326648 0,15030989 ! reproductive developmental process GO:0003006 127 89 2,000 0,0140791 0,15873492 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,01409921 0,15818628 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,01409921 0,15741838 ! meiosis I GO:0007127 52 32 1,000 0,01409921 0,15665791 ! leukocyte differentiation GO:0002521 143 90 2,000 0,01450584 0,16040116 ! sister chromatid segregation GO:0000819 46 33 1,000 0,01495403 0,16456583 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,01495403 0,16378219 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 55 33 1,000 0,01495403 0,16300597 ! cytokinesis GO:0000910 52 33 1,000 0,01495403 0,16223707 ! cell fate commitment GO:0045165 141 92 2,000 0,01538122 0,16608831 ! DNA recombination GO:0006310 146 92 2,000 0,01538122 0,1653122 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,01583065 0,16935116 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,01583065 0,16856713 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,01583065 0,16779032 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,01672882 0,17649675 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,01672882 0,17569083 ! glycogen metabolic process GO:0005977 48 35 1,000 0,01672882 0,17489223 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01672882 0,17410086 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! angiogenesis GO:0001525 149 95 2,000 0,01674919 0,17352769 ! in utero embryonic development GO:0001701 147 96 2,000 0,01721987 0,17760407 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01764827 0,1812099 GO:0090047|positive regulation of transcription regulator activity, ! glucan metabolic process GO:0044042 49 36 1,000 0,01764827 0,18040452 GO:0006073|cellular glucan metabolic process, ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,0186761 0,19006653 ! monocarboxylic acid transport GO:0015718 62 38 1,000 0,01954993 0,19808303 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,02053163 0,20711732 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,02053163 0,20621288 ! male sex differentiation GO:0046661 53 39 1,000 0,02053163 0,2053163 ! JNK cascade GO:0007254 54 39 1,000 0,02053163 0,20442748 ! developmental growth GO:0048589 62 39 1,000 0,02053163 0,20354633 ! cell growth GO:0016049 61 39 1,000 0,02053163 0,20267274 ! regulation of actin filament polymerization GO:0030833 59 40 1,000 0,02153356 0,21165462 ! response to calcium ion GO:0051592 58 40 1,000 0,02153356 0,21075397 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,02153356 0,20986094 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 0,02153356 0,20897545 ! T cell differentiation GO:0030217 65 40 1,000 0,02153356 0,2080974 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,02153356 0,2072267 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,02153356 0,20636326 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,02255546 0,21525958 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,02255546 0,21437008 ! biopolymer methylation GO:0043414 62 41 1,000 0,02255546 0,2134879 ! regulation of JNK cascade GO:0046328 58 41 1,000 0,02255546 0,21261295 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,02359709 0,22152366 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,02359709 0,22062316 ! positive regulation of binding GO:0051099 59 43 1,000 0,02465818 0,2296106 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,02465818 0,22868475 ! methylation GO:0032259 64 43 1,000 0,02465818 0,22776634 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,0257385 0,2367942 ! cell maturation GO:0048469 60 45 1,000 0,02683779 0,24592399 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,02795581 0,25515227 ! regulation of ossification GO:0030278 71 46 1,000 0,02795581 0,25414376 ! histone modification GO:0016570 68 46 1,000 0,02795581 0,25314319 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02799912 0,25254112 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02799912 0,25155463 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02799912 0,25057582 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02799912 0,24960459 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02799912 0,24864087 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02799912 0,24768456 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02799912 0,24673558 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02799912 0,24579384 ! sleep GO:0030431 11 5 0,000 0,02799912 0,24485926 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02799912 0,24393176 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02799912 0,24301127 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02799912 0,24209769 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02799912 0,24119096 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02799912 0,24029099 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02799912 0,23939772 ! tongue development GO:0043586 6 5 0,000 0,02799912 0,23851106 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02799912 0,23763094 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02799912 0,2367573 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02799912 0,23589006 ! cobalt ion transport GO:0006824 9 5 0,000 0,02799912 0,23502914 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02799912 0,23417449 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02799912 0,23332603 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02799912 0,2324837 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02799912 0,23164743 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02799912 0,23081715 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02799912 0,22999281 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02799912 0,22917433 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02799912 0,22836165 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02799912 0,22755472 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02799912 0,22675347 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02799912 0,22595784 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02799912 0,22516778 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02799912 0,22438322 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02799912 0,22360412 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02799912 0,2228304 ! malate metabolic process GO:0006108 7 5 0,000 0,02799912 0,22206202 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02799912 0,22129892 ! behavioral response to pain GO:0048266 7 5 0,000 0,02799912 0,22054105 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02799912 0,21978835 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02799912 0,21904077 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02799912 0,21829826 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02799912 0,21756076 ! mating behavior GO:0007617 6 5 0,000 0,02799912 0,21682823 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02799912 0,21610062 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02799912 0,21537788 ! rhythmic behavior GO:0007622 12 5 0,000 0,02799912 0,21465995 ! copulation GO:0007620 7 5 0,000 0,02799912 0,2139468 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02799912 0,21323836 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02799912 0,21253461 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02799912 0,21183548 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02799912 0,21114094 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02799912 0,21045093 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02799912 0,20976543 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02799912 0,20908437 ! response to protozoan GO:0001562 9 5 0,000 0,02799912 0,20840772 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02799912 0,20773544 ! lymph vessel development GO:0001945 7 5 0,000 0,02799912 0,20706748 ! endochondral ossification GO:0001958 12 5 0,000 0,02799912 0,2064038 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02799912 0,20574436 ! parathyroid gland development GO:0060017 8 5 0,000 0,02799912 0,20508913 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02799912 0,20443805 ! anagen GO:0042640 6 5 0,000 0,02799912 0,20379109 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02799912 0,20314822 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02799912 0,20250939 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02799912 0,20187456 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02799912 0,2012437 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02799912 0,20061678 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02799912 0,19999374 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02799912 0,19937457 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02799912 0,19875921 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02799912 0,19814765 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02799912 0,19753983 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02799912 0,19693574 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02799912 0,19633532 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02799912 0,19573856 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02799912 0,19514541 ! ovulation GO:0030728 6 5 0,000 0,02799912 0,19455585 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02799912 0,19396984 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,02799912 0,19338734 ! response to pH GO:0009268 9 5 0,000 0,02799912 0,19280834 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02799912 0,19223279 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02799912 0,19166067 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02799912 0,19109195 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02799912 0,19052658 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02799912 0,18996456 ! polyol catabolic process GO:0046174 7 5 0,000 0,02799912 0,18940584 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02799912 0,1888504 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02799912 0,1882982 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02799912 0,18774923 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02799912 0,18720345 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02799912 0,18666083 ! urea metabolic process GO:0019627 6 5 0,000 0,02799912 0,18612135 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02799912 0,18558497 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02799912 0,18505168 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02799912 0,18452145 ! neutrophil activation GO:0042119 5 5 0,000 0,02799912 0,18399424 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02799912 0,18347004 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02799912 0,18294882 ! response to food GO:0032094 5 5 0,000 0,02799912 0,18243055 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02799912 0,18191521 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02799912 0,18140278 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02799912 0,18089322 ! forebrain neuron development GO:0021884 7 5 0,000 0,02799912 0,18038651 ! melanosome organization GO:0032438 7 5 0,000 0,02799912 0,17988264 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02799912 0,17938158 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02799912 0,17888329 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02799912 0,17838777 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02799912 0,17789499 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02799912 0,17740492 ! nucleoside transport GO:0015858 6 5 0,000 0,02799912 0,17691754 ! nucleoside salvage GO:0043174 7 5 0,000 0,02799912 0,17643284 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02799912 0,17595078 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02799912 0,17547135 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02799912 0,17499453 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02799912 0,17452029 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02799912 0,17404861 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02799912 0,17357948 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02799912 0,17311286 ! depyrimidination GO:0045008 8 5 0,000 0,02799912 0,17264875 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02799912 0,17218713 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02799912 0,17172796 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02799912 0,17127124 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02799912 0,17081694 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02799912 0,17036504 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02799912 0,16991553 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02799912 0,16946838 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02799912 0,16902358 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02799912 0,16858111 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02799912 0,16814095 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02799912 0,16770309 ! centrosome duplication GO:0051298 5 5 0,000 0,02799912 0,16726749 ! response to UV-C GO:0010225 6 5 0,000 0,02799912 0,16683416 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02799912 0,16640306 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02799912 0,16597419 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02799912 0,16554752 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02799912 0,16512304 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02799912 0,16470073 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02799912 0,16428058 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02799912 0,16386256 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02799912 0,16344666 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02799912 0,16303287 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02799912 0,16262118 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02799912 0,16221155 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02799912 0,16180398 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02799912 0,16139846 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02799912 0,16099496 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02799912 0,16059348 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02799912 0,16019399 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02799912 0,15979649 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02799912 0,15940095 ! neural tube patterning GO:0021532 6 5 0,000 0,02799912 0,15900737 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02799912 0,15861573 ! histone demethylation GO:0016577 9 5 0,000 0,02799912 0,15822601 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02799912 0,1578382 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02799912 0,15745229 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02799912 0,15706826 ! enteric nervous system development GO:0048484 8 5 0,000 0,02799912 0,1566861 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02799912 0,15630579 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02799912 0,15592733 ! transcription termination GO:0006353 8 5 0,000 0,02799912 0,15555069 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02799912 0,15517587 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02799912 0,15480285 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02799912 0,15443162 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02799912 0,15406217 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02799912 0,15369448 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02799912 0,15332854 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02799912 0,15296434 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02799912 0,15260186 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02799912 0,1522411 ! apical protein localization GO:0045176 6 5 0,000 0,02799912 0,15188204 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02799912 0,15152467 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02799912 0,15116898 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02799912 0,15081495 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02799912 0,15046258 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02799912 0,15011185 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02799912 0,14976276 ! glial cell migration GO:0008347 10 5 0,000 0,02799912 0,14941528 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02799912 0,14906941 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02799912 0,14872514 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02799912 0,14838246 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02799912 0,14804135 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02799912 0,1477018 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02799912 0,14736381 ! neural plate development GO:0001840 6 5 0,000 0,02799912 0,14702736 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02799912 0,14669245 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02799912 0,14635906 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02799912 0,14602718 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02799912 0,1456968 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02799912 0,14536791 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02799912 0,14504051 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02799912 0,14471457 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02799912 0,1443901 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02799912 0,14406708 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02799912 0,1437455 ! spindle assembly GO:0051225 5 5 0,000 0,02799912 0,14342536 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02799912 0,14310663 GO:0022011|myelination in the peripheral nervous system, ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02799912 0,14278932 ! organ regeneration GO:0031100 7 5 0,000 0,02799912 0,14247342 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02799912 0,14215891 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02799912 0,14184578 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02799912 0,14153403 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02799912 0,14122365 GO:0055081|anion homeostasis, ! viral infectious cycle GO:0019058 71 47 1,000 0,02909232 0,1464165 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,02909232 0,14609682 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 1,000 0,02909232 0,14577852 ! regulation of muscle contraction GO:0006937 69 48 1,000 0,03024708 0,15123539 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,03024708 0,15090733 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,03024708 0,15058069 ! regulation of DNA replication GO:0006275 75 48 1,000 0,03024708 0,15025546 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,03141984 0,1557449 ! germ cell development GO:0007281 68 49 1,000 0,03141984 0,15540996 ! regulation of actin filament length GO:0030832 72 50 1,000 0,03261037 0,16095249 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,03261037 0,16060784 ! lipid modification GO:0030258 73 50 1,000 0,03261037 0,16026466 ! tRNA transcription GO:0009304 11 6 0,000 0,03350511 0,16431077 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03350511 0,16396117 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03350511 0,16361306 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03350511 0,16326642 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03350511 0,16292125 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03350511 0,16257753 ! regulation of helicase activity GO:0051095 11 6 0,000 0,03350511 0,16223526 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03350511 0,16189443 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03350511 0,16155503 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03350511 0,16121705 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03350511 0,16088048 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03350511 0,16054531 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03350511 0,16021154 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03350511 0,15987915 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03350511 0,15954814 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03350511 0,15921849 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03350511 0,1588902 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03350511 0,15856327 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03350511 0,15823768 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03350511 0,15791342 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03350511 0,15759049 ! neuron adhesion GO:0007158 9 6 0,000 0,03350511 0,15726888 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03350511 0,15694857 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03350511 0,15662957 ! signal peptide processing GO:0006465 8 6 0,000 0,03350511 0,15631186 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03350511 0,15599544 ! mRNA stabilization GO:0048255 15 6 0,000 0,03350511 0,1556803 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03350511 0,15536643 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03350511 0,15505382 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03350511 0,15474247 ! opsonization GO:0008228 8 6 0,000 0,03350511 0,15443236 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03350511 0,1541235 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03350511 0,15381587 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03350511 0,15350946 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03350511 0,15320427 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03350511 0,1529003 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03350511 0,15259752 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03350511 0,15229595 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03350511 0,15199556 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03350511 0,15169636 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03350511 0,15139833 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03350511 0,15110147 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03350511 0,15080577 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03350511 0,15051123 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03350511 0,15021783 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03350511 0,14992558 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03350511 0,14963446 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03350511 0,14934448 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03350511 0,14905561 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03350511 0,14876786 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03350511 0,14848121 ! thymic T cell selection GO:0045061 12 6 0,000 0,03350511 0,14819567 ! protein lipoylation GO:0009249 10 6 0,000 0,03350511 0,14791123 ! pigment granule organization GO:0048753 11 6 0,000 0,03350511 0,14762787 ! drug transport GO:0015893 6 6 0,000 0,03350511 0,1473456 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03350511 0,14706441 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,03350511 0,14678428 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03350511 0,14650523 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03350511 0,14622723 ! histidine metabolic process GO:0006547 6 6 0,000 0,03350511 0,14595028 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03350511 0,14567438 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03350511 0,14539953 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03350511 0,1451257 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03350511 0,14485291 ! adenohypophysis development GO:0021984 10 6 0,000 0,03350511 0,14458114 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03350511 0,14431039 ! hyperosmotic response GO:0006972 8 6 0,000 0,03350511 0,14404065 ! microtubule nucleation GO:0007020 10 6 0,000 0,03350511 0,14377192 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03350511 0,14350419 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03350511 0,14323745 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03350511 0,14297171 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03350511 0,14270694 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03350511 0,14244316 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03350511 0,14218035 ! response to dietary excess GO:0002021 7 6 0,000 0,03350511 0,14191851 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03350511 0,14165763 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03350511 0,14139771 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03350511 0,14113873 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03350511 0,14088071 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03350511 0,14062363 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03350511 0,14036748 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03350511 0,14011227 ! neuron apoptosis GO:0051402 8 6 0,000 0,03350511 0,13985798 ! organic alcohol transport GO:0015850 9 6 0,000 0,03350511 0,13960462 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03350511 0,13935217 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03350511 0,13910063 ! male sex determination GO:0030238 9 6 0,000 0,03350511 0,13885 ! carnitine transport GO:0015879 8 6 0,000 0,03350511 0,13860027 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03350511 0,13835143 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03350511 0,13810349 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03350511 0,13785644 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03350511 0,13761027 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03350511 0,13736497 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03350511 0,13712055 ! parturition GO:0007567 12 6 0,000 0,03350511 0,136877 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03350511 0,13663431 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03350511 0,13639248 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03350511 0,1361515 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03350511 0,13591137 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03350511 0,13567209 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03350511 0,13543365 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03350511 0,13519605 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03350511 0,13495928 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03350511 0,13472334 ! macrophage differentiation GO:0030225 10 6 0,000 0,03350511 0,13448822 ! astrocyte development GO:0014002 14 6 0,000 0,03350511 0,13425392 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03350511 0,13402043 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03350511 0,13378776 ! interaction with symbiont GO:0051702 8 6 0,000 0,03350511 0,13355589 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03350511 0,13332483 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03350511 0,13309456 ! eating behavior GO:0042755 6 6 0,000 0,03350511 0,13286508 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03350511 0,1326364 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03350511 0,1324085 ! response to copper ion GO:0046688 9 6 0,000 0,03350511 0,13218139 ! DNA topological change GO:0006265 8 6 0,000 0,03350511 0,13195505 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03350511 0,13172949 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03350511 0,13150469 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03350511 0,13128066 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03350511 0,1310574 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03350511 0,13083489 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03350511 0,13061313 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03350511 0,13039213 ! gas homeostasis GO:0033483 11 6 0,000 0,03350511 0,13017187 ! hair follicle maturation GO:0048820 7 6 0,000 0,03350511 0,12995236 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03350511 0,12973358 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03350511 0,12951554 ! Schwann cell development GO:0014044 14 6 0,000 0,03350511 0,12929824 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03350511 0,12908166 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03350511 0,1288658 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03350511 0,12865067 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03350511 0,12843625 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03350511 0,12822254 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03350511 0,12800955 ! histone ubiquitination GO:0016574 7 6 0,000 0,03350511 0,12779726 ! regulation of meiosis GO:0040020 10 6 0,000 0,03350511 0,12758568 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03350511 0,12737479 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03350511 0,1271646 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03350511 0,12695511 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03350511 0,1267463 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03350511 0,12653818 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03350511 0,12633074 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03350511 0,12612398 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03350511 0,12591789 ! receptor internalization GO:0031623 9 6 0,000 0,03350511 0,12571248 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03350511 0,12550773 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03350511 0,12530366 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03350511 0,12510024 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03350511 0,12489749 ! protein deubiquitination GO:0016579 8 6 0,000 0,03350511 0,12469539 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03350511 0,12449394 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,03350511 0,12429314 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03350511 0,12409299 ! axonal fasciculation GO:0007413 9 6 0,000 0,03350511 0,12389349 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03350511 0,12369462 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03350511 0,12349639 ! midbrain development GO:0030901 6 6 0,000 0,03350511 0,1232988 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03350511 0,12310184 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03350511 0,1229055 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03350511 0,12270979 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03350511 0,1225147 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03350511 0,12232024 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03350511 0,12212639 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03350511 0,12193315 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03350511 0,12174052 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03350511 0,1215485 ! adult feeding behavior GO:0008343 6 6 0,000 0,03350511 0,12135709 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03350511 0,12116627 ! pigment granule transport GO:0051904 12 6 0,000 0,03350511 0,12097606 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03350511 0,12078644 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03350511 0,12059742 ! catecholamine transport GO:0051937 7 6 0,000 0,03350511 0,12040898 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03350511 0,12022114 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03350511 0,12003388 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03350511 0,1198472 ! protein prenylation GO:0018342 10 6 0,000 0,03350511 0,1196611 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03350511 0,11947558 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03350511 0,11929063 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03350511 0,11910626 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03350511 0,11892245 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03350511 0,11873921 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,03381844 0,11966527 ! regulation of cellular component size GO:0032535 74 52 1,000 0,03504382 0,12381073 ! aging GO:0007568 79 52 1,000 0,03504382 0,12362084 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,03504382 0,12343152 ! establishment of organelle localization GO:0051656 85 52 1,000 0,03504382 0,12324279 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,03628627 0,12741743 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,03628627 0,1272232 ! kidney development GO:0001822 90 53 1,000 0,03628627 0,12702956 ! cell projection assembly GO:0030031 76 53 1,000 0,03628627 0,1268365 ! regulation of protein complex assembly GO:0043254 81 54 1,000 0,03754556 0,13103914 ! regulation of mitosis GO:0007088 84 54 1,000 0,03754556 0,1308406 GO:0051783|regulation of nuclear division, ! DNA catabolic process GO:0006308 67 54 1,000 0,03754556 0,13064265 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,03754556 0,13044531 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03898022 0,13522549 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03898022 0,13502184 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03898022 0,13481879 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03898022 0,13461636 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03898022 0,13441454 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03898022 0,13421332 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03898022 0,1340127 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03898022 0,13381268 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03898022 0,13361326 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03898022 0,13341443 ! reproductive behavior GO:0019098 12 7 0,000 0,03898022 0,13321619 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03898022 0,13301854 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03898022 0,13282148 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03898022 0,132625 ! oligopeptide transport GO:0006857 11 7 0,000 0,03898022 0,1324291 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03898022 0,13223377 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03898022 0,13203903 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03898022 0,13184485 ! RNA methylation GO:0001510 11 7 0,000 0,03898022 0,13165125 ! pericardium development GO:0060039 8 7 0,000 0,03898022 0,13145821 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03898022 0,13126574 ! fibril organization GO:0043206 13 7 0,000 0,03898022 0,13107383 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03898022 0,13088248 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03898022 0,13069169 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03898022 0,13050145 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03898022 0,13031177 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03898022 0,13012264 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03898022 0,12993406 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03898022 0,12974602 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03898022 0,12955852 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03898022 0,12937157 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03898022 0,12918516 ! chemosensory behavior GO:0007635 9 7 0,000 0,03898022 0,12899928 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03898022 0,12881393 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,03898022 0,12862912 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03898022 0,12844484 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03898022 0,12826109 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03898022 0,12807786 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03898022 0,12789515 ! reflex GO:0060004 12 7 0,000 0,03898022 0,12771296 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03898022 0,12753129 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03898022 0,12735014 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03898022 0,1271695 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03898022 0,12698937 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03898022 0,12680976 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03898022 0,12663065 ! spinal cord patterning GO:0021511 7 7 0,000 0,03898022 0,12645204 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03898022 0,12627394 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03898022 0,12609634 ! adrenal gland development GO:0030325 17 7 0,000 0,03898022 0,12591924 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03898022 0,12574263 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03898022 0,12556652 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03898022 0,12539091 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03898022 0,12521578 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03898022 0,12504114 ! endosome organization GO:0007032 10 7 0,000 0,03898022 0,12486699 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03898022 0,12469332 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03898022 0,12452014 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03898022 0,12434743 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03898022 0,12417521 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03898022 0,12400346 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03898022 0,12383218 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03898022 0,12366138 ! galactose metabolic process GO:0006012 10 7 0,000 0,03898022 0,12349104 ! vesicle fusion GO:0006906 15 7 0,000 0,03898022 0,12332118 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03898022 0,12315178 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03898022 0,12298285 ! organ growth GO:0035265 11 7 0,000 0,03898022 0,12281438 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03898022 0,12264637 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03898022 0,12247882 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03898022 0,12231173 ! retinol metabolic process GO:0042572 9 7 0,000 0,03898022 0,12214509 ! behavioral fear response GO:0001662 13 7 0,000 0,03898022 0,12197891 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03898022 0,12181318 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03898022 0,12164789 ! rRNA modification GO:0000154 12 7 0,000 0,03898022 0,12148306 ! protein heterooligomerization GO:0051291 10 7 0,000 0,03898022 0,12131867 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03898022 0,12115473 ! response to UV-B GO:0010224 11 7 0,000 0,03898022 0,12099123 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,03898022 0,12082817 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03898022 0,12066554 ! intermediate filament organization GO:0045109 11 7 0,000 0,03898022 0,12050336 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03898022 0,12034161 ! fibrinolysis GO:0042730 9 7 0,000 0,03898022 0,12018029 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03898022 0,12001941 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03898022 0,11985896 ! B cell lineage commitment GO:0002326 17 7 0,000 0,03898022 0,11969893 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03898022 0,11953933 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03898022 0,11938016 ! response to tropane GO:0014073 13 7 0,000 0,03898022 0,11922141 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! melanosome localization GO:0032400 10 7 0,000 0,03898022 0,11906308 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03898022 0,11890517 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03898022 0,11874768 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03898022 0,11859061 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03898022 0,11843395 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03898022 0,1182777 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03898022 0,11812187 ! mast cell activation GO:0045576 9 7 0,000 0,03898022 0,11796645 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03898022 0,11781143 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03898022 0,11765682 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03898022 0,11750262 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03898022 0,11734882 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03898022 0,11719542 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03898022 0,11704243 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,03898022 0,11688983 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03898022 0,11673763 ! T cell lineage commitment GO:0002360 12 7 0,000 0,03898022 0,11658582 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03898022 0,11643441 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03898022 0,1162834 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03898022 0,11613277 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03898022 0,11598253 ! response to tumor cell GO:0002347 12 7 0,000 0,03898022 0,11583269 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03898022 0,11568322 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03898022 0,11553415 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03898022 0,11538546 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03898022 0,11523714 ! diuresis GO:0030146 12 7 0,000 0,03898022 0,11508922 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03898022 0,11494166 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03898022 0,11479449 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03898022 0,1146477 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03898022 0,11450128 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03898022 0,11435523 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03898022 0,11420955 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03898022 0,11406425 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03898022 0,11391931 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03898022 0,11377474 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03898022 0,11363054 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03898022 0,11348671 ! lymph node development GO:0048535 9 7 0,000 0,03898022 0,11334323 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03898022 0,11320012 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03898022 0,11305738 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03898022 0,11291499 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03898022 0,11277295 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03898022 0,11263128 ! ATP catabolic process GO:0006200 10 7 0,000 0,03898022 0,11248996 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03898022 0,112349 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03898022 0,11220838 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03898022 0,11206812 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03898022 0,11192821 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03898022 0,11178865 ! muscle adaptation GO:0043500 12 7 0,000 0,03898022 0,11164944 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03898022 0,11151057 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03898022 0,11137205 ! retina homeostasis GO:0001895 9 7 0,000 0,03898022 0,11123387 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03898022 0,11109603 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03898022 0,11095854 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03898022 0,11082138 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03898022 0,11068457 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03898022 0,11054809 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03898022 0,11041194 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03898022 0,11027614 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,04011378 0,11334362 ! chromosome segregation GO:0007059 83 57 1,000 0,04142226 0,11689719 ! camera-type eye development GO:0043010 88 57 1,000 0,04142226 0,11675393 ! developmental maturation GO:0021700 75 57 1,000 0,04142226 0,11661103 ! gonad development GO:0008406 79 57 1,000 0,04142226 0,11646847 ! viral reproductive process GO:0022415 87 58 1,000 0,0427467 0,12004567 ! lung development GO:0030324 94 59 1,000 0,04408686 0,12365827 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04442462 0,12445387 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04442462 0,12430247 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,04442462 0,12415143 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,04442462 0,12400076 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04442462 0,12385046 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04442462 0,12370052 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04442462 0,12355094 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04442462 0,12340172 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04442462 0,12325287 ! phosphate transport GO:0006817 10 8 0,000 0,04442462 0,12310437 ! N-glycan processing GO:0006491 12 8 0,000 0,04442462 0,12295623 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04442462 0,12280845 ! UTP metabolic process GO:0046051 8 8 0,000 0,04442462 0,12266102 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04442462 0,12251394 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04442462 0,12236722 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,04442462 0,12222085 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04442462 0,12207482 ! succinate metabolic process GO:0006105 14 8 0,000 0,04442462 0,12192915 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04442462 0,12178382 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04442462 0,12163884 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,04442462 0,12149421 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04442462 0,12134991 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,04442462 0,12120596 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04442462 0,12106235 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04442462 0,12091909 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04442462 0,12077616 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04442462 0,12063356 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04442462 0,12049131 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04442462 0,12034938 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04442462 0,1202078 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04442462 0,12006654 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04442462 0,11992562 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04442462 0,11978503 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04442462 0,11964476 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04442462 0,11950483 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04442462 0,11936522 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04442462 0,11922594 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04442462 0,11908698 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04442462 0,11894834 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04442462 0,11881003 ! melanin metabolic process GO:0006582 12 8 0,000 0,04442462 0,11867204 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04442462 0,11853437 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04442462 0,11839702 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,04442462 0,11825999 ! macrophage activation GO:0042116 12 8 0,000 0,04442462 0,11812327 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04442462 0,11798687 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04442462 0,11785078 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04442462 0,11771501 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04442462 0,11757955 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04442462 0,1174444 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04442462 0,11730956 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04442462 0,11717503 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04442462 0,11704081 ! ruffle organization GO:0031529 11 8 0,000 0,04442462 0,1169069 ! osteoblast development GO:0002076 13 8 0,000 0,04442462 0,11677329 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04442462 0,11663999 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04442462 0,11650699 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04442462 0,11637429 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04442462 0,1162419 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04442462 0,1161098 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04442462 0,11597801 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04442462 0,11584652 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04442462 0,11571532 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04442462 0,11558442 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,04442462 0,11545382 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,04442462 0,11532351 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04442462 0,11519349 ! segment specification GO:0007379 10 8 0,000 0,04442462 0,11506377 ! cellular extravasation GO:0045123 11 8 0,000 0,04442462 0,11493434 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04442462 0,1148052 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04442462 0,11467635 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04442462 0,11454779 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,04442462 0,11441952 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04442462 0,11429153 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04442462 0,11416383 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04442462 0,11403641 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04442462 0,11390928 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04442462 0,11378244 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04442462 0,11365587 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04442462 0,11352959 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04442462 0,11340358 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04442462 0,11327786 ! icosanoid secretion GO:0032309 12 8 0,000 0,04442462 0,11315241 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04442462 0,11302724 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04442462 0,11290235 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04442462 0,11277773 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04442462 0,11265339 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04442462 0,11252933 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04442462 0,11240553 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04442462 0,11228201 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04442462 0,11215876 ! sterol catabolic process GO:0016127 9 8 0,000 0,04442462 0,11203578 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04442462 0,11191306 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04442462 0,11179062 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04442462 0,11166845 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04442462 0,11154654 ! prophase GO:0051324 11 8 0,000 0,04442462 0,11142489 ! S phase GO:0051320 8 8 0,000 0,04442462 0,11130352 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04442462 0,1111824 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04442462 0,11106155 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04442462 0,11094096 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04442462 0,11082064 ! hormone catabolic process GO:0042447 13 8 0,000 0,04442462 0,11070057 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04442462 0,11058077 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04442462 0,11046122 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04442462 0,11034193 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04442462 0,1102229 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04442462 0,11010412 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,04442462 0,10998561 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04442462 0,10986734 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04442462 0,10974933 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04442462 0,10963157 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04442462 0,10951407 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04442462 0,10939682 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04442462 0,10927982 ! regulation of embryonic development GO:0045995 16 8 0,000 0,04442462 0,10916306 ! mitochondrion localization GO:0051646 12 8 0,000 0,04442462 0,10904656 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,04442462 0,10893031 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,04544254 0,11130762 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,04544254 0,1111892 GO:0035113|embryonic appendage morphogenesis, ! regulation of heart contraction GO:0008016 91 60 1,000 0,04544254 0,11107104 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,04544254 0,11095313 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,04681353 0,11417933 ! meiosis GO:0007126 96 61 1,000 0,04681353 0,11405838 GO:0051327|M phase of meiotic cell cycle, ! homeostasis of number of cells GO:0048872 84 61 1,000 0,04681353 0,11393769 ! respiratory tube development GO:0030323 99 62 1,000 0,0481996 0,11718719 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,0481996 0,11706344 ! meiotic cell cycle GO:0051321 97 62 1,000 0,0481996 0,11693996 ! organelle localization GO:0051640 96 62 1,000 0,0481996 0,11681673 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,04960055 0,12008554 GO:0090046|regulation of transcription regulator activity, ! viral reproduction GO:0016032 92 63 1,000 0,04960055 0,11995927 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04983849 0,12040812 ! regulation of developmental growth GO:0048638 13 9 0,000 0,04983849 0,12028177 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,04983849 0,12015569 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04983849 0,12002987 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04983849 0,11990432 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04983849 0,11977903 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04983849 0,119654 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04983849 0,11952923 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04983849 0,11940472 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04983849 0,11928047 ! GTP metabolic process GO:0046039 9 9 0,000 0,04983849 0,11915647 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04983849 0,11903274 ! social behavior GO:0035176 14 9 0,000 0,04983849 0,11890926 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04983849 0,11878604 ! artery development GO:0060840 19 9 0,000 0,04983849 0,11866307 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04983849 0,11854036 ! regulation of glycolysis GO:0006110 15 9 0,000 0,04983849 0,1184179 ! response to pain GO:0048265 16 9 0,000 0,04983849 0,11829569 ! protein complex disassembly GO:0043241 17 9 0,000 0,04983849 0,11817374 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04983849 0,11805204 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04983849 0,11793058 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04983849 0,11780938 ! lung alveolus development GO:0048286 17 9 0,000 0,04983849 0,11768843 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04983849 0,11756772 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,04983849 0,11744726 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04983849 0,11732705 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04983849 0,11720708 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04983849 0,11708736 ! protein targeting to ER GO:0045047 19 9 0,000 0,04983849 0,11696789 ! T cell selection GO:0045058 18 9 0,000 0,04983849 0,11684865 ! endoderm development GO:0007492 12 9 0,000 0,04983849 0,11672966 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04983849 0,11661091 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04983849 0,11649241 ! arginine catabolic process GO:0006527 10 9 0,000 0,04983849 0,11637414 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04983849 0,11625611 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04983849 0,11613833 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04983849 0,11602078 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04983849 0,11590347 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,04983849 0,11578639 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04983849 0,11566955 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04983849 0,11555295 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04983849 0,11543658 ! mannose metabolic process GO:0006013 9 9 0,000 0,04983849 0,11532045 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04983849 0,11520455 ! receptor clustering GO:0043113 15 9 0,000 0,04983849 0,11508888 ! epithelial cell development GO:0002064 10 9 0,000 0,04983849 0,11497345 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04983849 0,11485824 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04983849 0,11474327 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04983849 0,11462853 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04983849 0,11451401 ! motor axon guidance GO:0008045 14 9 0,000 0,04983849 0,11439973 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04983849 0,11428567 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04983849 0,11417184 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04983849 0,11405824 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04983849 0,11394486 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04983849 0,11383171 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04983849 0,11371878 ! DNA ligation GO:0006266 14 9 0,000 0,04983849 0,11360607 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04983849 0,11349359 ! response to amine stimulus GO:0014075 13 9 0,000 0,04983849 0,11338133 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04983849 0,1132693 ! erythrocyte development GO:0048821 11 9 0,000 0,04983849 0,11315748 ! renal water homeostasis GO:0003091 14 9 0,000 0,04983849 0,11304589 ! postreplication repair GO:0006301 11 9 0,000 0,04983849 0,11293451 ! mRNA cleavage GO:0006379 13 9 0,000 0,04983849 0,11282335 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04983849 0,11271242 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04983849 0,1126017 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04983849 0,1124912 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04983849 0,11238091 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04983849 0,11227084 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,04983849 0,11216099 ! acid secretion GO:0046717 14 9 0,000 0,04983849 0,11205135 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04983849 0,11194192 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04983849 0,11183271 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04983849 0,11172371 ! purine base metabolic process GO:0006144 18 9 0,000 0,04983849 0,11161493 ! oocyte differentiation GO:0009994 12 9 0,000 0,04983849 0,11150635 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,04983849 0,11139799 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04983849 0,11128983 ! spleen development GO:0048536 15 9 0,000 0,04983849 0,11118189 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,04983849 0,11107416 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04983849 0,11096663 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04983849 0,11085931 ! detection of calcium ion GO:0005513 13 9 0,000 0,04983849 0,1107522 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04983849 0,1106453 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04983849 0,1105386 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04983849 0,11043211 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04983849 0,11032582 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04983849 0,11021974 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04983849 0,11011386 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04983849 0,11000818 ! prepulse inhibition GO:0060134 14 9 0,000 0,04983849 0,10990271 ! embryonic placenta development GO:0001892 12 9 0,000 0,04983849 0,10979744 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04983849 0,10969237 ! insulin secretion GO:0030073 17 9 0,000 0,04983849 0,1095875 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04983849 0,10948284 ! response to nicotine GO:0035094 16 9 0,000 0,04983849 0,10937837 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04983849 0,1092741 ! nucleus localization GO:0051647 15 9 0,000 0,04983849 0,10917003 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04983849 0,10906615 ! localization within membrane GO:0051668 15 9 0,000 0,04983849 0,10896248 ! appendage morphogenesis GO:0035107 93 64 1,000 0,05101617 0,11143133 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,05101617 0,1113256 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,05101617 0,11122008 ! respiratory system development GO:0060541 100 64 1,000 0,05101617 0,11111476 ! appendage development GO:0048736 94 65 1,000 0,05244625 0,11412145 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,05244625 0,11401358 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,05244625 0,11390592 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,05244625 0,11379846 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,05389059 0,11682219 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,055222 0,11959566 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,055222 0,11948315 ! neuron fate specification GO:0048665 11 10 0,000 0,055222 0,11937086 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,055222 0,11925877 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,055222 0,1191469 ! thyroid gland development GO:0030878 19 10 0,000 0,055222 0,11903523 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,055222 0,11892377 ! synapsis GO:0007129 13 10 0,000 0,055222 0,11881253 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,055222 0,11870149 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,055222 0,11859065 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,055222 0,11848003 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,055222 0,11836961 ! sulfate transport GO:0008272 12 10 0,000 0,055222 0,1182594 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,055222 0,11814939 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,055222 0,11803958 ! androgen metabolic process GO:0008209 13 10 0,000 0,055222 0,11792998 ! phospholipid efflux GO:0033700 16 10 0,000 0,055222 0,11782059 ! hippocampus development GO:0021766 19 10 0,000 0,055222 0,11771139 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,055222 0,1176024 ! blood vessel remodeling GO:0001974 21 10 0,000 0,055222 0,11749361 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,055222 0,11738502 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,055222 0,11727663 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,055222 0,11716844 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,055222 0,11706045 ! pathogenesis GO:0009405 13 10 0,000 0,055222 0,11695266 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,055222 0,11684507 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,055222 0,11673768 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,055222 0,11663048 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,055222 0,11652348 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,055222 0,11641667 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,055222 0,11631006 ! glucan biosynthetic process GO:0009250 13 10 0,000 0,055222 0,11620365 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,055222 0,11609743 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,055222 0,11599141 ! response to X-ray GO:0010165 16 10 0,000 0,055222 0,11588558 ! B cell proliferation GO:0042100 14 10 0,000 0,055222 0,11577994 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,055222 0,11567449 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,055222 0,11556924 ! forebrain cell migration GO:0021885 17 10 0,000 0,055222 0,11546417 ! lipid digestion GO:0044241 15 10 0,000 0,055222 0,1153593 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,055222 0,11525462 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,055222 0,11515013 ! UV protection GO:0009650 14 10 0,000 0,055222 0,11504582 ! entry into host cell GO:0030260 20 10 0,000 0,055222 0,11494171 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,055222 0,11483779 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,055222 0,11473405 ! negative regulation of ossification GO:0030279 19 10 0,000 0,055222 0,1146305 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,055222 0,11452713 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,055222 0,11442396 ! regulation of bone resorption GO:0045124 24 10 0,000 0,055222 0,11432096 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,055222 0,11421816 ! regulation of organ growth GO:0046620 11 10 0,000 0,055222 0,11411554 ! response to dsRNA GO:0043331 18 10 0,000 0,055222 0,1140131 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,055222 0,11391084 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,055222 0,11380877 ! embryonic axis specification GO:0000578 12 10 0,000 0,055222 0,11370689 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,055222 0,11360518 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,055222 0,11350366 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,055222 0,11340231 ! cranial nerve development GO:0021545 12 10 0,000 0,055222 0,11330115 ! fucose catabolic process GO:0019317 16 10 0,000 0,055222 0,11320017 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,055222 0,11309937 ! protein sumoylation GO:0016925 12 10 0,000 0,055222 0,11299875 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,055222 0,1128983 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,055222 0,11279804 ! zymogen activation GO:0031638 14 10 0,000 0,055222 0,11269795 ! salivary gland development GO:0007431 22 10 0,000 0,055222 0,11259804 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,055222 0,11249831 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,055222 0,11239875 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,055222 0,11229937 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,055222 0,11220017 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,055222 0,11210114 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,055222 0,11200228 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,055222 0,1119036 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,055222 0,1118051 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,055222 0,11170676 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,055222 0,1116086 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,055222 0,11151062 ! embryonic gut development GO:0048566 11 10 0,000 0,055222 0,1114128 ! activation of innate immune response GO:0002218 10 10 0,000 0,055222 0,11131515 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,055222 0,11121768 ! developmental induction GO:0031128 13 10 0,000 0,055222 0,11112038 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,055222 0,11102324 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,055222 0,11092628 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,055222 0,11082949 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,055222 0,11073286 ! learning or memory GO:0007611 123 68 1,000 0,05682121 0,11384041 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,05682121 0,11374133 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,05682121 0,11364243 ! response to drug GO:0042493 108 69 1,000 0,0583071 0,11651289 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,0583071 0,11641175 ! response to metal ion GO:0010038 103 70 1,000 0,05980645 0,11930167 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,05980645 0,11919829 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,05980645 0,11909509 ! rRNA transcription GO:0009303 17 11 0,000 0,06057531 0,1205218 ! respiratory burst GO:0045730 14 11 0,000 0,06057531 0,12041763 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,06057531 0,12031365 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,06057531 0,12020984 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,06057531 0,12010621 ! virus-host interaction GO:0019048 17 11 0,000 0,06057531 0,12000276 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,06057531 0,11989949 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,06057531 0,11979639 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,06057531 0,11969347 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,06057531 0,11959073 ! RNA polyadenylation GO:0043631 19 11 0,000 0,06057531 0,11948817 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,06057531 0,11938578 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,06057531 0,11928356 ! mating GO:0007618 14 11 0,000 0,06057531 0,11918152 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,06057531 0,11907966 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,06057531 0,11897797 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,06057531 0,11887645 ! bone resorption GO:0045453 16 11 0,000 0,06057531 0,11877511 ! regulated secretory pathway GO:0045055 14 11 0,000 0,06057531 0,11867394 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,06057531 0,11857294 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,06057531 0,11847211 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,06057531 0,11837145 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,06057531 0,11827097 ! syncytium formation GO:0006949 15 11 0,000 0,06057531 0,11817066 ! plasma membrane organization GO:0007009 18 11 0,000 0,06057531 0,11807051 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,06057531 0,11797054 ! focal adhesion formation GO:0048041 24 11 0,000 0,06057531 0,11787073 ! mitotic spindle organization GO:0007052 15 11 0,000 0,06057531 0,11777109 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,06057531 0,11767162 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,06057531 0,11757232 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,06057531 0,11747319 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,06057531 0,11737422 ! adult heart development GO:0007512 11 11 0,000 0,06057531 0,11727542 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,06057531 0,11717679 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,06057531 0,11707832 ! temperature homeostasis GO:0001659 16 11 0,000 0,06057531 0,11698002 ! L-glutamate transport GO:0015813 16 11 0,000 0,06057531 0,11688188 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,06057531 0,11678391 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,06057531 0,1166861 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,06057531 0,11658845 ! stem cell development GO:0048864 29 11 0,000 0,06057531 0,11649097 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,06057531 0,11639365 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,06057531 0,1162965 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,06057531 0,1161995 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,06057531 0,11610267 ! vasoconstriction GO:0042310 15 11 0,000 0,06057531 0,116006 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,06057531 0,11590949 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,06057531 0,11581314 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,06057531 0,11571695 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,06057531 0,11562091 ! ribosome assembly GO:0042255 13 11 0,000 0,06057531 0,11552504 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,06057531 0,11542933 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,06057531 0,11533378 ! nucleosome positioning GO:0016584 13 11 0,000 0,06057531 0,11523838 ! T cell homeostasis GO:0043029 20 11 0,000 0,06057531 0,11514314 ! regulation of isotype switching GO:0045191 19 11 0,000 0,06057531 0,11504806 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,06057531 0,11495314 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,06057531 0,11485837 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,06057531 0,11476376 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,06057531 0,1146693 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,06057531 0,114575 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,06057531 0,11448086 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,06057531 0,11438687 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,06057531 0,11429303 ! male genitalia development GO:0030539 13 11 0,000 0,06057531 0,11419935 ! cholesterol efflux GO:0033344 19 11 0,000 0,06057531 0,11410582 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,06057531 0,11401244 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,06057531 0,11391922 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,06057531 0,11382615 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,06057531 0,11373323 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,06057531 0,11364046 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,06057531 0,11354784 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,06057531 0,11345538 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,06057531 0,11336306 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,06057531 0,1132709 ! actin filament polymerization GO:0030041 17 11 0,000 0,06057531 0,11317888 ! acrosome reaction GO:0007340 13 11 0,000 0,06057531 0,11308701 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,06057531 0,1129953 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,06131904 0,11428995 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,06131904 0,11419741 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,0628447 0,11694403 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,0628447 0,11684949 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,0628447 0,11675511 ! regulation of blood pressure GO:0008217 107 73 1,000 0,06438323 0,1195169 ! lactation GO:0007595 20 12 0,000 0,06589859 0,12223125 ! reproductive cellular process GO:0048610 14 12 0,000 0,06589859 0,12213276 ! tRNA modification GO:0006400 14 12 0,000 0,06589859 0,12203442 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06589859 0,12193624 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06589859 0,12183822 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,06589859 0,12174036 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06589859 0,12164266 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06589859 0,12154511 ! non-recombinational repair GO:0000726 19 12 0,000 0,06589859 0,12144772 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06589859 0,12135048 ! peroxisomal transport GO:0043574 21 12 0,000 0,06589859 0,1212534 ! cartilage condensation GO:0001502 18 12 0,000 0,06589859 0,12115647 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06589859 0,1210597 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06589859 0,12096309 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,06589859 0,12086663 ! palate development GO:0060021 15 12 0,000 0,06589859 0,12077032 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06589859 0,12067416 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06589859 0,12057816 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,06589859 0,12048231 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06589859 0,12038662 ! arginine metabolic process GO:0006525 13 12 0,000 0,06589859 0,12029107 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06589859 0,12019568 ! methionine metabolic process GO:0006555 13 12 0,000 0,06589859 0,12010044 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06589859 0,12000534 ! Golgi organization GO:0007030 18 12 0,000 0,06589859 0,1199104 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,06589859 0,11981561 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06589859 0,11972097 ! monoamine transport GO:0015844 13 12 0,000 0,06589859 0,11962648 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06589859 0,11953214 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,06589859 0,11943794 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06589859 0,1193439 ! L-amino acid transport GO:0015807 20 12 0,000 0,06589859 0,11925 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06589859 0,11915625 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06589859 0,11906265 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06589859 0,11896919 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06589859 0,11887588 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06589859 0,11878272 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06589859 0,1186897 ! cerebellum development GO:0021549 13 12 0,000 0,06589859 0,11859683 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06589859 0,1185041 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06589859 0,11841152 ! histone methylation GO:0016571 15 12 0,000 0,06589859 0,11831909 ! autonomic nervous system development GO:0048483 23 12 0,000 0,06589859 0,11822679 ! gland morphogenesis GO:0022612 23 12 0,000 0,06589859 0,11813464 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06589859 0,11804264 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06589859 0,11795078 ! response to gamma radiation GO:0010332 20 12 0,000 0,06589859 0,11785906 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06589859 0,11776748 ! intestinal absorption GO:0050892 19 12 0,000 0,06589859 0,11767605 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06589859 0,11758475 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06589859 0,1174936 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,06589859 0,11740259 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06589859 0,11731173 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,06589859 0,117221 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06589859 0,11713041 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06589859 0,11703996 ! microspike assembly GO:0030035 23 12 0,000 0,06589859 0,11694965 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06589859 0,11685948 ! response to cold GO:0009409 14 12 0,000 0,06589859 0,11676945 ! response to oxygen levels GO:0070482 137 74 1,000 0,06593444 0,11674304 ! protein import into nucleus GO:0006606 118 74 1,000 0,06593444 0,11665323 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,06593444 0,11656357 ! response to inorganic substance GO:0010035 115 75 1,000 0,06749813 0,11923633 ! regulation of ligase activity GO:0051340 114 75 1,000 0,06749813 0,11914482 ! nuclear import GO:0051170 121 75 1,000 0,06749813 0,11905345 ! response to unfolded protein GO:0006986 99 76 1,000 0,06907412 0,12173983 ! regulation of protein transport GO:0051223 114 76 1,000 0,06907412 0,12164661 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 1,000 0,07066223 0,12434822 ! regulation of DNA binding GO:0051101 119 77 1,000 0,07066223 0,12425315 ! gland development GO:0048732 148 77 1,000 0,07066223 0,12415823 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,07066223 0,12406345 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,07066223 0,12396882 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,07119201 0,12480306 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,07119201 0,12470801 ! cGMP metabolic process GO:0046068 16 13 0,000 0,07119201 0,1246131 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,07119201 0,12451834 ! water transport GO:0006833 17 13 0,000 0,07119201 0,12442372 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,07119201 0,12432924 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,07119201 0,12423491 ! lipid localization GO:0010876 24 13 0,000 0,07119201 0,12414072 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,07119201 0,12404668 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,07119201 0,12395277 ! organelle fusion GO:0048284 28 13 0,000 0,07119201 0,12385901 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,07119201 0,12376539 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,07119201 0,12367191 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,07119201 0,12357858 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,07119201 0,12348538 ! response to hexose stimulus GO:0009746 19 13 0,000 0,07119201 0,12339232 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,07119201 0,12329941 ! glutamate metabolic process GO:0006536 18 13 0,000 0,07119201 0,12320663 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,07119201 0,123114 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,07119201 0,1230215 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,07119201 0,12292914 ! NAD metabolic process GO:0019674 21 13 0,000 0,07119201 0,12283692 ! exocrine system development GO:0035272 27 13 0,000 0,07119201 0,12274484 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,07119201 0,12265289 ! bone mineralization GO:0030282 15 13 0,000 0,07119201 0,12256109 ! regulation of exocytosis GO:0017157 17 13 0,000 0,07119201 0,12246942 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,07119201 0,12237789 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,07119201 0,12228649 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,07119201 0,12219523 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,07119201 0,12210411 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,07119201 0,12201313 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,07119201 0,12192227 ! genitalia development GO:0048806 15 13 0,000 0,07119201 0,12183156 ! regulation of cellular pH GO:0030641 20 13 0,000 0,07119201 0,12174098 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,07119201 0,12165053 ! cellular pigmentation GO:0033059 24 13 0,000 0,07119201 0,12156022 ! tissue regeneration GO:0042246 21 13 0,000 0,07119201 0,12147004 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,07119201 0,12138 ! cofactor transport GO:0051181 19 13 0,000 0,07119201 0,12129008 ! NADP metabolic process GO:0006739 18 13 0,000 0,07119201 0,12120031 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,07119201 0,12111066 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,07119201 0,12102115 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07119201 0,12093177 ! gas transport GO:0015669 18 13 0,000 0,07119201 0,12084252 ! regulation of RNA stability GO:0043487 28 13 0,000 0,07119201 0,1207534 ! heme biosynthetic process GO:0006783 20 13 0,000 0,07119201 0,12066442 ! regulation of axon extension GO:0030516 23 13 0,000 0,07119201 0,12057556 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,07119201 0,12048684 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,07119201 0,12039825 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,07119201 0,12030978 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,07119201 0,12022145 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,07119201 0,12013325 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,07119201 0,12004517 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,07226226 0,12176059 ! protein localization in nucleus GO:0034504 133 80 1,000 0,07549739 0,12711859 ! forebrain development GO:0030900 131 80 1,000 0,07549739 0,1270256 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,07645573 0,12854399 ! superoxide anion generation GO:0042554 18 14 0,000 0,07645573 0,12845009 ! neuron maturation GO:0042551 21 14 0,000 0,07645573 0,12835633 ! regulation of S phase GO:0033261 18 14 0,000 0,07645573 0,12826271 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,07645573 0,12816923 ! myotube differentiation GO:0014902 21 14 0,000 0,07645573 0,12807588 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,07645573 0,12798266 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07645573 0,12788958 ! inositol metabolic process GO:0006020 20 14 0,000 0,07645573 0,12779664 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07645573 0,12770383 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07645573 0,12761116 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07645573 0,12751862 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07645573 0,12742622 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07645573 0,12733395 ! response to cAMP GO:0051591 19 14 0,000 0,07645573 0,12724181 ! limbic system development GO:0021761 25 14 0,000 0,07645573 0,1271498 ! startle response GO:0001964 21 14 0,000 0,07645573 0,12705793 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07645573 0,12696619 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,07645573 0,12687459 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07645573 0,12678311 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,07645573 0,12669177 ! glycine metabolic process GO:0006544 22 14 0,000 0,07645573 0,12660056 ! pituitary gland development GO:0021983 23 14 0,000 0,07645573 0,12650948 ! cellular response to starvation GO:0009267 21 14 0,000 0,07645573 0,12641853 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,07645573 0,12632771 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,07645573 0,12623703 ! regulation of heart rate GO:0002027 23 14 0,000 0,07645573 0,12614647 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07645573 0,12605604 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,07645573 0,12596574 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,07645573 0,12587558 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,07645573 0,12578554 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,07645573 0,12569562 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07645573 0,12560584 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,07645573 0,12551619 ! axon cargo transport GO:0008088 27 14 0,000 0,07645573 0,12542666 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07645573 0,12533726 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07645573 0,12524799 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,07645573 0,12515885 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,07645573 0,12506983 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07645573 0,12498094 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07645573 0,12489217 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07645573 0,12480353 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07645573 0,12471502 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,07645573 0,12462663 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07645573 0,12453837 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07645573 0,12445023 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,07645573 0,12436222 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07645573 0,12427433 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,07645573 0,12418657 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07645573 0,12409893 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07645573 0,12401141 ! cell killing GO:0001906 20 14 0,000 0,07645573 0,12392402 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,07645573 0,12383675 ! cilium assembly GO:0042384 20 14 0,000 0,07645573 0,1237496 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07645573 0,12366257 ! response to protein stimulus GO:0051789 111 81 1,000 0,07713212 0,12466892 ! regulation of neurological system process GO:0031644 122 81 1,000 0,07713212 0,12458137 ! vitamin metabolic process GO:0006766 103 81 1,000 0,07713212 0,12449394 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,07713212 0,12440664 GO:0002696|positive regulation of leukocyte activation, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,08043503 0,129643 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,08043503 0,12955221 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,08168992 0,13148133 ! positive regulation of cell size GO:0045793 20 15 0,000 0,08168992 0,13138939 ! metencephalon development GO:0022037 19 15 0,000 0,08168992 0,13129757 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,08168992 0,13120588 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,08168992 0,13111432 ! skin development GO:0043588 25 15 0,000 0,08168992 0,13102289 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,08168992 0,13093158 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,08168992 0,13084041 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,08168992 0,13074935 ! bile acid metabolic process GO:0008206 22 15 0,000 0,08168992 0,13065843 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,08168992 0,13056763 ! adult walking behavior GO:0007628 25 15 0,000 0,08168992 0,13047696 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,08168992 0,13038641 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,08168992 0,13029599 ! myoblast differentiation GO:0045445 27 15 0,000 0,08168992 0,1302057 ! centrosome cycle GO:0007098 16 15 0,000 0,08168992 0,13011553 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,08168992 0,13002548 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,08168992 0,12993556 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,08168992 0,12984577 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,08168992 0,12975609 ! cerebral cortex development GO:0021987 29 15 0,000 0,08168992 0,12966654 ! response to osmotic stress GO:0006970 22 15 0,000 0,08168992 0,12957712 ! vesicle coating GO:0006901 25 15 0,000 0,08168992 0,12948782 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,08168992 0,12939864 ! peptide secretion GO:0002790 27 15 0,000 0,08168992 0,12930958 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,08168992 0,12922065 ! regulation of vasodilation GO:0042312 24 15 0,000 0,08168992 0,12913184 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,08168992 0,12904315 ! neuron recognition GO:0008038 22 15 0,000 0,08168992 0,12895458 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,08168992 0,12886613 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,08168992 0,12877781 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,08168992 0,1286896 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,08168992 0,12860152 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,08168992 0,12851356 ! biomineral formation GO:0031214 18 15 0,000 0,08168992 0,12842572 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,08168992 0,12833799 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,08168992 0,12825039 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,08168992 0,12816291 ! organic cation transport GO:0015695 19 15 0,000 0,08168992 0,12807554 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,08168992 0,1279883 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,08168992 0,12790117 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,08168992 0,12781417 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,08168992 0,12772728 ! defense response to virus GO:0051607 27 15 0,000 0,08168992 0,1276405 ! peptide hormone processing GO:0016486 19 15 0,000 0,08168992 0,12755385 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,08168992 0,12746732 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,08210285 0,12802479 ! sterol metabolic process GO:0016125 120 84 1,000 0,08210285 0,12793805 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,08378136 0,13046522 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,08378136 0,13037695 ! regulation of protein localization GO:0032880 132 85 1,000 0,08378136 0,1302888 ! protein secretion GO:0009306 27 16 0,000 0,08689475 0,13503914 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,08689475 0,13494796 ! hormone secretion GO:0046879 25 16 0,000 0,08689475 0,1348569 ! bone remodeling GO:0046849 24 16 0,000 0,08689475 0,13476596 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,08689475 0,13467515 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08689475 0,13458446 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,08689475 0,13449389 ! glial cell development GO:0021782 24 16 0,000 0,08689475 0,13440344 ! patterning of blood vessels GO:0001569 24 16 0,000 0,08689475 0,13431312 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,08689475 0,13422292 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,08689475 0,13413283 ! protein polyubiquitination GO:0000209 26 16 0,000 0,08689475 0,13404287 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,08689475 0,13395303 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,08689475 0,13386331 ! fructose metabolic process GO:0006000 20 16 0,000 0,08689475 0,13377371 ! regulation of protein binding GO:0043393 27 16 0,000 0,08689475 0,13368423 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,08689475 0,13359487 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,08689475 0,13350563 ! protein export from nucleus GO:0006611 24 16 0,000 0,08689475 0,1334165 ! negative regulation of immune response GO:0050777 28 16 0,000 0,08689475 0,1333275 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,08689475 0,13323862 ! DNA replication initiation GO:0006270 25 16 0,000 0,08689475 0,13314985 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,08689475 0,1330612 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,08689475 0,13297267 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,08689475 0,13288426 ! diencephalon development GO:0021536 25 16 0,000 0,08689475 0,13279596 ! oogenesis GO:0048477 23 16 0,000 0,08689475 0,13270778 ! neural crest cell migration GO:0001755 24 16 0,000 0,08689475 0,13261972 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,08689475 0,13253178 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,08689475 0,13244395 GO:0006626|protein targeting to mitochondrion, ! steroid catabolic process GO:0006706 22 16 0,000 0,08689475 0,13235624 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,08689475 0,13226865 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,08689475 0,13218117 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,08689475 0,1320938 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,08689475 0,13200655 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,08689475 0,13191942 ! sperm-egg recognition GO:0035036 16 16 0,000 0,08689475 0,1318324 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,08689475 0,1317455 ! nerve development GO:0021675 18 16 0,000 0,08689475 0,13165871 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,08689475 0,13157204 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,08689475 0,13148548 ! negative regulation of translation GO:0017148 22 16 0,000 0,08689475 0,13139903 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,08716975 0,13172827 GO:0060538|skeletal muscle organ development, ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,08887929 0,13422348 ! protein processing GO:0016485 114 88 1,000 0,08887929 0,13413541 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,09207037 0,13886023 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,09207037 0,13876924 ! negative regulation of defense response GO:0031348 19 17 0,000 0,09207037 0,13867836 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,09207037 0,1385876 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,09207037 0,13849696 ! glycerol metabolic process GO:0006071 20 17 0,000 0,09207037 0,13840644 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,09207037 0,13831604 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,09207037 0,13822575 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,09207037 0,13813559 ! signal complex assembly GO:0007172 29 17 0,000 0,09207037 0,13804554 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,09207037 0,13795561 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,09207037 0,13786579 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,09207037 0,13777609 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,09207037 0,13768651 ! memory GO:0007613 25 17 0,000 0,09207037 0,13759705 ! keratinization GO:0031424 17 17 0,000 0,09207037 0,1375077 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,09207037 0,13741846 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,09207037 0,13732935 ! retinoid metabolic process GO:0001523 22 17 0,000 0,09207037 0,13724035 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,09207037 0,13715146 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,09207037 0,13706269 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,09207037 0,13697403 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,09207037 0,13688549 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,09207037 0,13679706 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,09207037 0,13670875 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,09207037 0,13662055 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,09207037 0,13653247 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,09207037 0,13644449 ! membrane budding GO:0006900 29 17 0,000 0,09207037 0,13635663 ! heme metabolic process GO:0042168 27 17 0,000 0,09207037 0,13626889 ! actin filament bundle formation GO:0051017 26 17 0,000 0,09207037 0,13618126 ! neuromuscular junction development GO:0007528 23 17 0,000 0,09207037 0,13609374 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,09207037 0,13600633 ! body fluid secretion GO:0007589 27 17 0,000 0,09207037 0,13591903 ! stem cell differentiation GO:0048863 36 17 0,000 0,09207037 0,13583185 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,09207037 0,13574478 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,09207037 0,13565782 ! sensory perception of pain GO:0019233 23 17 0,000 0,09207037 0,13557097 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,09207037 0,13548423 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,09207037 0,1353976 ! synaptogenesis GO:0007416 24 17 0,000 0,09207037 0,13531109 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,09207037 0,13522468 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,09207037 0,13513839 ! cell-cell junction organization GO:0045216 25 17 0,000 0,09207037 0,1350522 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,09207037 0,13496613 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,09207037 0,13488016 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,09207037 0,13479431 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,09207037 0,13470856 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,09207037 0,13462292 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,09207037 0,13453739 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,09581586 0,13992157 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,09721695 0,14187753 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,09721695 0,14178756 ! positive regulation of translation GO:0045727 28 18 0,000 0,09721695 0,14169771 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,09721695 0,14160797 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,09721695 0,14151835 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,09721695 0,14142884 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,09721695 0,14133944 ! cAMP metabolic process GO:0046058 33 18 0,000 0,09721695 0,14125015 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,09721695 0,14116098 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,09721695 0,14107192 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,09721695 0,14098297 ! axis specification GO:0009798 26 18 0,000 0,09721695 0,14089413 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,09721695 0,14080541 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,09721695 0,1407168 ! pancreas development GO:0031016 26 18 0,000 0,09721695 0,1406283 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,09721695 0,14053991 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,09721695 0,14045163 ! glutamine metabolic process GO:0006541 23 18 0,000 0,09721695 0,14036346 ! central nervous system neuron development GO:0021954 30 18 0,000 0,09721695 0,1402754 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,09721695 0,14018745 ! fucose metabolic process GO:0006004 26 18 0,000 0,09721695 0,14009962 ! response to fungus GO:0009620 19 18 0,000 0,09721695 0,14001189 ! peptide cross-linking GO:0018149 31 18 0,000 0,09721695 0,13992427 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,09721695 0,13983677 ! heart process GO:0003015 27 18 0,000 0,09721695 0,13974937 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,09721695 0,13966208 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,09721695 0,1395749 ! visual learning GO:0008542 35 18 0,000 0,09721695 0,13948783 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,09721695 0,13940087 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,09721695 0,13931401 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,09721695 0,13922727 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,09721695 0,13914063 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,09721695 0,1390541 ! vitamin transport GO:0051180 24 18 0,000 0,09721695 0,13896768 ! hormone transport GO:0009914 27 18 0,000 0,09721695 0,13888136 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,09721695 0,13879515 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,09721695 0,13870905 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,09721695 0,13862306 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,09721695 0,13853717 ! cell-cell recognition GO:0009988 20 18 0,000 0,09721695 0,13845139 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,09721695 0,13836571 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,09721695 0,13828014 ! regulation of glucose import GO:0046324 21 18 0,000 0,09721695 0,13819468 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,09721695 0,13810932 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,09721695 0,13802407 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,09721695 0,13793892 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,09757379 0,13835988 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,09757379 0,13827463 ! regulation of binding GO:0051098 151 95 1,000 0,10111709 0,1432077 ! carboxylic acid transport GO:0046942 147 95 1,000 0,10111709 0,14311957 GO:0015849|organic acid transport, ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,10233465 0,14475381 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,10233465 0,14466484 ! positive regulation of ossification GO:0045778 30 19 0,000 0,10233465 0,14457598 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,10233465 0,14448723 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,10233465 0,14439859 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,10233465 0,14431006 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,10233465 0,14422163 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,10233465 0,14413331 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,10233465 0,1440451 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,10233465 0,143957 ! regeneration GO:0031099 32 19 0,000 0,10233465 0,14386901 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,10233465 0,14378112 ! response to alkaloid GO:0043279 32 19 0,000 0,10233465 0,14369335 ! sensory perception of taste GO:0050909 23 19 0,000 0,10233465 0,14360567 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,10233465 0,14351811 ! smooth muscle contraction GO:0006939 36 19 0,000 0,10233465 0,14343065 ! peroxisome organization GO:0007031 29 19 0,000 0,10233465 0,1433433 ! digestive system process GO:0022600 30 19 0,000 0,10233465 0,14325606 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,10233465 0,14316892 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,10233465 0,14308189 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,10233465 0,14299496 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,10233465 0,14290814 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,10233465 0,14282142 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,10233465 0,14273481 ! response to starvation GO:0042594 30 19 0,000 0,10233465 0,1426483 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,10233465 0,1425619 ! plasma membrane fusion GO:0045026 23 19 0,000 0,10233465 0,14247561 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,10233465 0,14238941 ! cytolysis GO:0019835 20 19 0,000 0,10233465 0,14230333 ! renal system process GO:0003014 35 19 0,000 0,10233465 0,14221734 ! vasodilation GO:0042311 33 19 0,000 0,10233465 0,14213146 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,10233465 0,14204569 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,10233465 0,14196001 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,10233465 0,14187444 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,10233465 0,14178898 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,10233465 0,14170361 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,10233465 0,14161835 ! sarcomere organization GO:0045214 23 19 0,000 0,10233465 0,14153319 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,10233465 0,14144814 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,10233465 0,14136318 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,10233465 0,14127833 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,10233465 0,14119358 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,10233465 0,14110893 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,10233465 0,14102439 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,10233465 0,14093994 ! protein stabilization GO:0050821 26 19 0,000 0,10233465 0,1408556 ! protein maturation GO:0051604 129 96 1,000 0,10290214 0,14155198 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,10742363 0,14768342 ! iron ion transport GO:0006826 37 20 0,000 0,10742363 0,1475952 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,10742363 0,14750708 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,10742363 0,14741907 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,10742363 0,14733116 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,10742363 0,14724336 ! spinal cord development GO:0021510 31 20 0,000 0,10742363 0,14715566 ! response to ethanol GO:0045471 37 20 0,000 0,10742363 0,14706807 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,10742363 0,14698058 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,10742363 0,1468932 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,10742363 0,14680592 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,10742363 0,14671874 ! chromosome condensation GO:0030261 31 20 0,000 0,10742363 0,14663167 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,10742363 0,1465447 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,10742363 0,14645783 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,10742363 0,14637106 ! pallium development GO:0021543 38 20 0,000 0,10742363 0,1462844 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,10742363 0,14619784 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,10742363 0,14611139 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,10742363 0,14602503 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,10742363 0,14593878 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,10742363 0,14585263 ! collagen catabolic process GO:0030574 25 20 0,000 0,10742363 0,14576658 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,10742363 0,14568063 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,10742363 0,14559479 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,10742363 0,14550904 ! alditol metabolic process GO:0019400 24 20 0,000 0,10742363 0,1454234 ! actin filament-based movement GO:0030048 34 20 0,000 0,10742363 0,14533786 ! protein import GO:0017038 156 99 1,000 0,10830902 0,14644959 ! regulation of translation GO:0006417 151 100 1,000 0,11012806 0,1488217 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,11012806 0,14873431 ! protein localization in organelle GO:0033365 161 100 1,000 0,11012806 0,14864702 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,11248405 0,15173802 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,11248405 0,15164908 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,11248405 0,15156024 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,11248405 0,1514715 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,11248405 0,15138287 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,11248405 0,15129434 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,11248405 0,15120592 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,11248405 0,1511176 GO:0034105|positive regulation of tissue remodeling, ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,11248405 0,15102938 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,11248405 0,15094126 ! vesicle docking GO:0048278 27 21 0,000 0,11248405 0,15085325 ! phototransduction GO:0007602 25 21 0,000 0,11248405 0,15076534 ! dendrite development GO:0016358 35 21 0,000 0,11248405 0,15067753 ! visual behavior GO:0007632 39 21 0,000 0,11248405 0,15058983 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,11248405 0,15050222 ! ovarian follicle development GO:0001541 30 21 0,000 0,11248405 0,15041472 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,11248405 0,15032732 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,11248405 0,15024003 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,11248405 0,15015283 ! cell aging GO:0007569 32 21 0,000 0,11248405 0,15006573 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,11248405 0,14997874 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,11248405 0,14989184 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,11248405 0,14980505 ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,11248405 0,14971836 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,11248405 0,14963177 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,11248405 0,14954527 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,11248405 0,14945888 ! immunoglobulin production GO:0002377 33 21 0,000 0,11248405 0,14937259 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,11248405 0,1492864 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,11248405 0,1492003 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,11248405 0,14911431 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,11248405 0,14902841 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,11248405 0,14894262 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,11248405 0,14885692 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,11248405 0,14877132 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,11248405 0,14868582 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,11248405 0,14860042 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,11248405 0,14851511 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,11248405 0,1484299 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,11248405 0,1483448 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,11248405 0,14825978 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,11751607 0,15480353 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,11751607 0,15471492 ! viral genome replication GO:0019079 29 22 0,000 0,11751607 0,15462641 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,11751607 0,154538 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,11751607 0,1544497 ! leukocyte adhesion GO:0007159 38 22 0,000 0,11751607 0,15436149 ! molting cycle process GO:0022404 40 22 0,000 0,11751607 0,15427338 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,11751607 0,15418538 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,11751607 0,15409747 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,11751607 0,15400967 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,11751607 0,15392196 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,11751607 0,15383436 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,11751607 0,15374685 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,11751607 0,15365945 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,11751607 0,15357214 ! ureteric bud development GO:0001657 32 22 0,000 0,11751607 0,15348493 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,11751607 0,15339782 ! regulation of behavior GO:0050795 38 22 0,000 0,11751607 0,15331081 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,11751607 0,1532239 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,11751607 0,15313709 ! membrane depolarization GO:0051899 35 22 0,000 0,11751607 0,15305038 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,11751607 0,15296376 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,11751607 0,15287724 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,11751607 0,15279082 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,11751607 0,1527045 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,11751607 0,15261828 ! neural tube closure GO:0001843 33 22 0,000 0,11751607 0,15253215 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,11751607 0,15244612 ! protein tetramerization GO:0051262 39 22 0,000 0,11751607 0,15236018 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,12251985 0,15875811 ! neuron fate commitment GO:0048663 32 23 0,000 0,12251985 0,15866872 ! embryonic pattern specification GO:0009880 31 23 0,000 0,12251985 0,15857943 ! myelination GO:0042552 35 23 0,000 0,12251985 0,15849024 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,12251985 0,15840115 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,12251985 0,15831216 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,12251985 0,15822327 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,12251985 0,15813448 ! vesicle targeting GO:0006903 32 23 0,000 0,12251985 0,15804579 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,12251985 0,1579572 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,12251985 0,15786871 ! osteoblast differentiation GO:0001649 40 23 0,000 0,12251985 0,15778032 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,12251985 0,15769202 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,12251985 0,15760383 ! interaction with host GO:0051701 37 23 0,000 0,12251985 0,15751573 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,12251985 0,15742774 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,12251985 0,15733984 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,12251985 0,15725204 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,12251985 0,15716433 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,12251985 0,15707673 ! pentose metabolic process GO:0019321 31 23 0,000 0,12251985 0,15698922 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,12251985 0,15690181 ! spermatid development GO:0007286 33 23 0,000 0,12251985 0,1568145 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,12251985 0,15672728 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,12251985 0,15664016 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,12251985 0,15655314 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,12251985 0,15646621 ! telomere organization GO:0032200 32 23 0,000 0,12251985 0,15637938 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,12251985 0,15629265 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,12251985 0,15620601 ! regulation of amine transport GO:0051952 38 23 0,000 0,12251985 0,15611947 ! liver development GO:0001889 40 23 0,000 0,12251985 0,15603303 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,12749554 0,16227987 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,12749554 0,16219012 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,12749554 0,16210046 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,12749554 0,1620109 ! superoxide metabolic process GO:0006801 32 24 0,000 0,12749554 0,16192144 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,12749554 0,16183208 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,12749554 0,16174282 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,12749554 0,16165366 ! sperm motility GO:0030317 27 24 0,000 0,12749554 0,16156459 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,12749554 0,16147562 ! vacuole organization GO:0007033 39 24 0,000 0,12749554 0,16138675 ! neural crest cell development GO:0014032 39 24 0,000 0,12749554 0,16129798 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,12749554 0,16120931 ! negative regulation of cell development GO:0010721 56 24 0,000 0,12749554 0,16112073 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,12749554 0,16103225 ! base-excision repair GO:0006284 31 24 0,000 0,12749554 0,16094387 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,12749554 0,16085558 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,12749554 0,1607674 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,12749554 0,1606793 ! glutathione metabolic process GO:0006749 29 24 0,000 0,12749554 0,16059131 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,12749554 0,16050341 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,13244329 0,1666409 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,13244329 0,16654979 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,13244329 0,16645878 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,13244329 0,16636787 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,13244329 0,16627706 ! peptide transport GO:0015833 43 25 0,000 0,13244329 0,16618635 ! iron ion homeostasis GO:0055072 39 25 0,000 0,13244329 0,16609573 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,13244329 0,16600522 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,13244329 0,1659148 ! phospholipid transport GO:0015914 35 25 0,000 0,13244329 0,16582448 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,13244329 0,16573426 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,13244329 0,16564414 ! detection of light stimulus GO:0009583 30 25 0,000 0,13244329 0,16555412 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,13244329 0,16546419 ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,13244329 0,16537436 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,13736327 0,1714246 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,13736327 0,17133163 ! translational initiation GO:0006413 43 26 0,000 0,13736327 0,17123877 ! regulation of pH GO:0006885 36 26 0,000 0,13736327 0,17114601 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,13736327 0,17105335 ! circadian rhythm GO:0007623 42 26 0,000 0,13736327 0,17096078 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,13736327 0,17086832 ! post-embryonic development GO:0009791 42 26 0,000 0,13736327 0,17077596 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,13736327 0,1706837 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,13736327 0,17059154 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,13736327 0,17049948 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,13736327 0,17040751 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,13736327 0,17031565 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,13736327 0,17022388 ! regulation of coagulation GO:0050818 39 26 0,000 0,13736327 0,17013222 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,14225563 0,17609686 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,14225563 0,17600213 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,14225563 0,1759075 ! membrane docking GO:0022406 39 27 0,000 0,14225563 0,17581298 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,14225563 0,17571856 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,14225563 0,17562424 ! acute-phase response GO:0006953 42 27 0,000 0,14225563 0,17553002 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,14225563 0,1754359 ! myofibril assembly GO:0030239 36 27 0,000 0,14225563 0,17534188 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,14225563 0,17524797 ! response to ionizing radiation GO:0010212 47 27 0,000 0,14225563 0,17515415 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,14225563 0,17506044 ! lipid oxidation GO:0034440 38 27 0,000 0,14225563 0,17496682 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,14225563 0,17487331 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,14225563 0,17477989 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,14225563 0,17468658 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,14225563 0,17459336 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,14225563 0,17450024 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,14225563 0,17440723 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,14712053 0,18027555 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,14712053 0,18017956 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,14712053 0,18008367 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,14712053 0,17998788 ! cell junction assembly GO:0034329 56 28 0,000 0,14712053 0,17989219 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,14712053 0,1797966 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,14712053 0,17970112 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,14712053 0,17960574 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,14712053 0,17951046 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,14712053 0,17941528 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,14712053 0,1793202 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,14712053 0,17922522 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,14712053 0,17913034 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,14712053 0,17903556 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,14712053 0,17894088 ! mesoderm formation GO:0001707 46 28 0,000 0,14712053 0,1788463 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,14712053 0,17875183 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,14712053 0,17865745 ! ensheathment of neurons GO:0007272 43 28 0,000 0,14712053 0,17856317 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,14712053 0,17846899 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,14712053 0,17837491 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,14712053 0,17828093 ! neural tube formation GO:0001841 41 28 0,000 0,14712053 0,17818705 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,14712053 0,17809327 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,1519581 0,18385252 ! regulation of innate immune response GO:0045088 38 29 0,000 0,1519581 0,18375585 ! ovulation cycle process GO:0022602 41 29 0,000 0,1519581 0,18365929 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,1519581 0,18356283 ! protein targeting to membrane GO:0006612 53 29 0,000 0,1519581 0,18346648 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,1519581 0,18337022 ! mismatch repair GO:0006298 34 29 0,000 0,1519581 0,18327406 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,1519581 0,18317801 ! muscle cell development GO:0055001 38 29 0,000 0,1519581 0,18308205 ! formation of primary germ layer GO:0001704 48 29 0,000 0,1519581 0,1829862 ! telencephalon development GO:0021537 52 29 0,000 0,1519581 0,18289044 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,1519581 0,18279479 ! eye morphogenesis GO:0048592 51 29 0,000 0,1519581 0,18269923 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,1519581 0,18260378 ! tissue homeostasis GO:0001894 42 29 0,000 0,1519581 0,18250843 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,15676852 0,18818768 ! collagen metabolic process GO:0032963 40 30 0,000 0,15676852 0,18808951 ! organic anion transport GO:0015711 51 30 0,000 0,15676852 0,18799144 ! cholesterol transport GO:0030301 46 30 0,000 0,15676852 0,18789348 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,15676852 0,18779562 ! spliceosome assembly GO:0000245 49 30 0,000 0,15676852 0,18769786 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,15676852 0,1876002 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,15676852 0,18750265 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,15676852 0,18740519 ! ceramide metabolic process GO:0006672 43 30 0,000 0,15676852 0,18730784 ! ovulation cycle GO:0042698 43 30 0,000 0,15676852 0,18721059 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,15676852 0,18711343 ! adult locomotory behavior GO:0008344 47 30 0,000 0,15676852 0,18701638 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,15676852 0,18691943 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,15676852 0,18682258 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,15676852 0,18672583 ! response to heat GO:0009408 41 30 0,000 0,15676852 0,18662919 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,15676852 0,18653264 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,15676852 0,18643619 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,16155192 0,19202553 ! negative regulation of secretion GO:0051048 49 31 0,000 0,16155192 0,19192635 ! mammary gland development GO:0030879 57 31 0,000 0,16155192 0,19182726 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,16155192 0,19172828 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,16155192 0,1916294 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,16155192 0,19153062 ! odontogenesis GO:0042476 50 31 0,000 0,16155192 0,19143195 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,16155192 0,19133337 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,16155192 0,1912349 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,16155192 0,19113653 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,16155192 0,19103826 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,16155192 0,19094009 ! cell fate specification GO:0001708 37 31 0,000 0,16155192 0,19084202 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,16155192 0,19074405 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,16155192 0,19064618 ! RNA modification GO:0009451 40 31 0,000 0,16155192 0,19054842 ! regulation of muscle development GO:0048634 48 32 0,000 0,16630846 0,19605815 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,16630846 0,19595771 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,16630846 0,19585737 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,16630846 0,19575714 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,16630846 0,19565701 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,16630846 0,19555698 ! peripheral nervous system development GO:0007422 53 32 0,000 0,16630846 0,19545705 ! regulation of protein stability GO:0031647 48 32 0,000 0,16630846 0,19535723 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,16630846 0,1952575 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,16630846 0,19515788 ! cytokine production GO:0001816 44 32 0,000 0,16630846 0,19505836 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,16630846 0,19495894 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,16630846 0,19485963 ! vesicle localization GO:0051648 47 32 0,000 0,16630846 0,19476041 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,17103828 0,20019748 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,17103828 0,20009565 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,17103828 0,19999392 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,17103828 0,1998923 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,17103828 0,19979078 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,17103828 0,19968936 ! ear morphogenesis GO:0042471 42 33 0,000 0,17103828 0,19958805 ! actomyosin structure organization GO:0031032 43 33 0,000 0,17103828 0,19948684 ! cell junction organization GO:0034330 63 33 0,000 0,17103828 0,19938573 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,17103828 0,19928473 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,17103828 0,19918382 ! nucleus organization GO:0006997 49 33 0,000 0,17103828 0,19908302 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,17103828 0,19898232 ! female gonad development GO:0008585 49 33 0,000 0,17103828 0,19888172 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,17103828 0,19878123 ! positive regulation of cell development GO:0010720 54 33 0,000 0,17103828 0,19868083 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,17103828 0,19858054 ! regulation of proteolysis GO:0030162 50 33 0,000 0,17103828 0,19848035 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,17103828 0,19838026 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,17103828 0,19828027 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,17103828 0,19818038 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,17574154 0,20352747 ! mRNA catabolic process GO:0006402 48 34 0,000 0,17574154 0,20342504 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,17574154 0,20332271 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,17574154 0,20322049 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,17574154 0,20311837 ! feeding behavior GO:0007631 45 34 0,000 0,17574154 0,20301635 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,17574154 0,20291443 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,17574154 0,20281262 ! neuron migration GO:0001764 46 34 0,000 0,17574154 0,20271091 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,17574154 0,2026093 ! female gamete generation GO:0007292 43 34 0,000 0,17574154 0,20250779 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,17574154 0,20240638 ! polyol metabolic process GO:0019751 44 34 0,000 0,17574154 0,20230508 ! aerobic respiration GO:0009060 47 34 0,000 0,17574154 0,20220388 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,17574154 0,20210278 ! embryonic organ development GO:0048568 45 34 0,000 0,17574154 0,20200177 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,17574154 0,20190087 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,18041839 0,20717039 ! Notch signaling pathway GO:0007219 56 35 0,000 0,18041839 0,20706701 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,18041839 0,20696374 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,18041839 0,20686056 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,18041839 0,2067575 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,18041839 0,20665453 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,18041839 0,20655166 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,18041839 0,2064489 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,18041839 0,20634624 ! pigment metabolic process GO:0042440 61 35 0,000 0,18041839 0,20624368 ! protein homooligomerization GO:0051260 52 35 0,000 0,18041839 0,20614123 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,18506896 0,21134986 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,18506896 0,21124497 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,18506896 0,21114019 ! negative regulation of binding GO:0051100 58 36 0,000 0,18506896 0,21103551 ! organic ether metabolic process GO:0018904 46 36 0,000 0,18506896 0,21093093 ! tissue remodeling GO:0048771 62 36 0,000 0,18506896 0,21082646 ! neural tube development GO:0021915 50 36 0,000 0,18506896 0,21072209 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,18506896 0,21061782 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,18506896 0,21051366 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,18506896 0,2104096 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,18506896 0,21030564 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,18969341 0,21545425 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,18969341 0,2153479 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,18969341 0,21524166 ! learning GO:0007612 67 37 0,000 0,18969341 0,21513553 ! ion transmembrane transport GO:0034220 56 37 0,000 0,18969341 0,2150295 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,18969341 0,21492357 ! regulation of protein secretion GO:0050708 51 37 0,000 0,18969341 0,21481775 ! amino acid activation GO:0043038 52 37 0,000 0,18969341 0,21471203 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,18969341 0,21460642 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,19429189 0,21970076 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,19429189 0,2195928 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,19429189 0,21948494 ! phagocytosis GO:0006909 60 38 0,000 0,19429189 0,21937719 ! maintenance of location in cell GO:0051651 69 38 0,000 0,19429189 0,21926955 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,19886453 0,22431996 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,19886453 0,22421 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,19886453 0,22410015 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,19886453 0,22399041 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,19886453 0,22388077 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,19886453 0,22377124 ! chromatin remodeling GO:0006338 68 39 0,000 0,19886453 0,22366181 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,19886453 0,2235525 ! synapse organization GO:0050808 55 39 0,000 0,19886453 0,22344329 ! regulation of tube size GO:0035150 60 40 0,000 0,20341147 0,22844062 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,20341147 0,22832913 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,20341147 0,22821775 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,20341147 0,22810648 ! peptide metabolic process GO:0006518 56 40 0,000 0,20341147 0,22799532 ! inner ear development GO:0048839 57 40 0,000 0,20341147 0,22788426 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,20341147 0,22777331 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,20341147 0,22766248 ! B cell differentiation GO:0030183 62 40 0,000 0,20341147 0,22755174 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,20341147 0,22744112 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,20793287 0,23238368 ! glucose transport GO:0015758 52 41 0,000 0,20793287 0,23227082 ! endosome transport GO:0016197 71 41 0,000 0,20793287 0,23215806 ! striated muscle contraction GO:0006941 62 41 0,000 0,20793287 0,23204542 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,20793287 0,23193288 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,20793287 0,23182046 ! mitochondrial transport GO:0006839 60 42 0,000 0,21242887 0,23671822 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,21242887 0,23660358 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,21242887 0,23648906 ! cellular component disassembly GO:0022411 64 42 0,000 0,21242887 0,23637465 ! hexose transport GO:0008645 54 42 0,000 0,21242887 0,23626035 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,21242887 0,23614616 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,21242887 0,23603208 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,21242887 0,23591811 ! excretion GO:0007588 63 42 0,000 0,21242887 0,23580425 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,21242887 0,2356905 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,21242887 0,23557685 ! regulation of cell shape GO:0008360 78 42 0,000 0,21242887 0,23546332 ! leukocyte migration GO:0050900 60 43 0,000 0,2168996 0,24030302 ! neuromuscular process GO:0050905 79 43 0,000 0,2168996 0,24018733 ! activation of caspase activity GO:0006919 65 43 0,000 0,2168996 0,24007174 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,2168996 0,23995627 ! tRNA processing GO:0008033 49 43 0,000 0,2168996 0,2398409 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,2168996 0,23972565 ! vesicle organization GO:0016050 79 43 0,000 0,2168996 0,23961051 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,2168996 0,23949548 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,22134521 0,24428694 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,22134521 0,24416977 ! glycolysis GO:0006096 53 44 0,000 0,22134521 0,24405272 ! regulation of action potential GO:0001508 71 44 0,000 0,22134521 0,24393578 ! regulation of ion transport GO:0043269 57 44 0,000 0,22134521 0,24381895 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,22134521 0,24370224 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,22134521 0,24358563 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,22134521 0,24346914 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,22134521 0,24335276 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,22134521 0,24323649 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,22134521 0,24312033 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,22134521 0,24300428 ! RNA catabolic process GO:0006401 64 45 0,000 0,22576583 0,24773922 ! positive regulation of defense response GO:0031349 59 45 0,000 0,22576583 0,24762108 ! regulation of translational initiation GO:0006446 64 45 0,000 0,22576583 0,24750305 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,22576583 0,24738514 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,22576583 0,24726734 ! cell recognition GO:0008037 58 45 0,000 0,22576583 0,24714965 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,22576583 0,24703207 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,23016161 0,25172216 ! cell redox homeostasis GO:0045454 63 46 0,000 0,23016161 0,25160252 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,23016161 0,25148299 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,23016161 0,25136358 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,23453268 0,25601574 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,23453268 0,25589429 ! endocrine system development GO:0035270 83 47 0,000 0,23453268 0,25577295 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,23453268 0,25565173 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,23453268 0,25553063 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,23453268 0,25540964 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,23453268 0,25528876 ! chloride transport GO:0006821 67 48 0,000 0,23887918 0,25989693 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,23887918 0,25977405 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,23887918 0,25965128 ! gastrulation GO:0007369 73 48 0,000 0,23887918 0,25952863 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,23887918 0,2594061 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,23887918 0,25928368 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,23887918 0,25916137 ! regulation of endocytosis GO:0030100 63 48 0,000 0,23887918 0,25903919 ! nuclear export GO:0051168 69 48 0,000 0,23887918 0,25891711 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,23887918 0,25879516 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,23887918 0,25867331 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,24320125 0,26322959 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,24320125 0,26310577 ! sensory perception of smell GO:0007608 61 49 0,000 0,24320125 0,26298208 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,24320125 0,26285849 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,24320125 0,26273503 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,24320125 0,26261168 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,24320125 0,26248844 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,24320125 0,26236533 ! cartilage development GO:0051216 70 49 0,000 0,24320125 0,26224232 ! maintenance of location GO:0051235 84 49 0,000 0,24320125 0,26211944 ! ear development GO:0043583 72 50 0,000 0,24749902 0,26662658 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,24749902 0,26650176 ! membrane fusion GO:0006944 80 50 0,000 0,24749902 0,26637705 ! positive regulation of growth GO:0045927 67 50 0,000 0,24749902 0,26625246 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,24749902 0,26612798 ! proton transport GO:0015992 75 50 0,000 0,24749902 0,26600362 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,24749902 0,26587938 ! positive regulation of secretion GO:0051047 71 51 0,000 0,25177263 0,2703441 ! hydrogen transport GO:0006818 77 51 0,000 0,25177263 0,27021795 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,25177263 0,27009191 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,25177263 0,26996599 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,25177263 0,2698402 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,25177263 0,26971451 ! adult behavior GO:0030534 80 51 0,000 0,25177263 0,26958895 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,25177263 0,2694635 ! transition metal ion transport GO:0000041 74 52 0,000 0,25602222 0,27388423 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,25602222 0,27375691 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,25602222 0,2736297 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,26024791 0,27801681 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,26024791 0,27788774 ! single fertilization GO:0007338 59 53 0,000 0,26024791 0,27775879 ! amino acid transport GO:0006865 84 54 0,000 0,26444984 0,28211254 ! glucose catabolic process GO:0006007 66 54 0,000 0,26444984 0,28198175 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,26444984 0,28185108 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,26444984 0,28172054 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,26444984 0,28159011 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,26444984 0,2814598 ! exocytosis GO:0006887 74 55 0,000 0,26862814 0,28577462 ! mesoderm development GO:0007498 76 55 0,000 0,26862814 0,2856425 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,26862814 0,2855105 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,26862814 0,28537863 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,27278295 0,28965872 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,27278295 0,28952505 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,27278295 0,28939151 ! carbohydrate transport GO:0008643 74 57 0,000 0,27691439 0,29363905 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,27691439 0,29350373 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,27691439 0,29336854 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,27691439 0,29323347 ! secondary metabolic process GO:0019748 84 57 0,000 0,27691439 0,29309853 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,2810226 0,29731002 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,2810226 0,29717332 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,2851077 0,30135464 ! activation of MAPK activity GO:0000187 84 59 0,000 0,2851077 0,30121622 ! actin filament organization GO:0007015 95 59 0,000 0,2851077 0,30107792 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,2851077 0,30093974 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,28916982 0,30508742 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,28916982 0,30494754 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,28916982 0,30480778 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,28916982 0,30466815 ! fertilization GO:0009566 68 60 0,000 0,28916982 0,30452865 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,29320909 0,30864115 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,29320909 0,30849996 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,29320909 0,3083589 ! extracellular matrix organization GO:0030198 103 61 0,000 0,29320909 0,30821796 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,29320909 0,30807716 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,29320909 0,30793649 ! amine catabolic process GO:0009310 90 62 0,000 0,29722564 0,31201231 ! neurotransmitter transport GO:0006836 81 62 0,000 0,29722564 0,31186997 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,29722564 0,31172775 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,29722564 0,31158567 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,30121959 0,31562873 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,30121959 0,315485 ! regulation of lipase activity GO:0060191 109 63 0,000 0,30121959 0,3153414 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,30519107 0,31935372 ! hexose catabolic process GO:0019320 82 64 0,000 0,30519107 0,31920849 ! adaptive immune response GO:0002250 94 64 0,000 0,30519107 0,3190634 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 0,000 0,30914021 0,3230452 ! B cell activation GO:0042113 104 65 0,000 0,30914021 0,3228985 ! defense response to bacterium GO:0042742 73 65 0,000 0,30914021 0,32275192 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,30914021 0,32260548 ! activation of immune response GO:0002253 83 65 0,000 0,30914021 0,32245918 ! protein oligomerization GO:0051259 100 65 0,000 0,30914021 0,322313 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,31306713 0,32625935 ! antigen processing and presentation GO:0019882 96 66 0,000 0,31306713 0,32611159 ! axon guidance GO:0007411 99 66 0,000 0,31306713 0,32596396 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,31306713 0,32581647 ! regulation of immune effector process GO:0002697 101 66 0,000 0,31306713 0,32566911 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,31697195 0,32958204 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,31697195 0,32943312 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,31697195 0,32928432 ! acute inflammatory response GO:0002526 92 68 0,000 0,3208548 0,33316751 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,3208548 0,33301716 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,3208548 0,33286695 ! rhythmic process GO:0048511 105 68 0,000 0,3208548 0,33271688 ! inorganic anion transport GO:0015698 93 68 0,000 0,3208548 0,33256694 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,32471579 0,33641726 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,32471579 0,33626579 ! humoral immune response GO:0006959 86 70 0,000 0,32855506 0,34008849 ! amine transport GO:0015837 101 70 0,000 0,32855506 0,33993551 ! regulation of catabolic process GO:0009894 106 70 0,000 0,32855506 0,33978266 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,33237271 0,34357629 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,33237271 0,34342194 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,33237271 0,34326773 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,33616888 0,34703251 ! negative regulation of transport GO:0051051 116 73 0,000 0,33994368 0,35077186 ! tube morphogenesis GO:0035239 118 73 0,000 0,33994368 0,35061456 ! mitochondrion organization GO:0007005 104 73 0,000 0,33994368 0,35045741 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,33994368 0,35030039 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,33994368 0,35014352 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,34369724 0,35385123 ! digestion GO:0007586 97 74 0,000 0,34369724 0,35369291 ! blood coagulation GO:0007596 116 75 0,000 0,34742966 0,35737398 GO:0050817|coagulation, ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,34742966 0,35721422 ! amine biosynthetic process GO:0009309 97 76 0,000 0,35114106 0,36086883 ! tRNA metabolic process GO:0006399 95 76 0,000 0,35114106 0,36070766 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,35114106 0,36054663 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,35483157 0,36417341 ! protein ubiquitination GO:0016567 125 77 0,000 0,35483157 0,36401098 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,35483157 0,36384869 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,35850131 0,36744786 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,35850131 0,36728419 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,36215037 0,37085746 ! cellular respiration GO:0045333 107 79 0,000 0,36215037 0,37069242 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,36215037 0,37052752 ! regulation of lyase activity GO:0051339 133 79 0,000 0,36215037 0,37036277 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,36215037 0,37019816 ! chromatin assembly GO:0031497 102 80 0,000 0,36577889 0,3737412 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,36577889 0,37357525 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,36577889 0,37340943 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,36577889 0,37324377 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,36938698 0,37675834 ! hemostasis GO:0007599 125 81 0,000 0,36938698 0,37659133 ! mRNA transport GO:0051028 121 81 0,000 0,36938698 0,37642448 ! ossification GO:0001503 134 82 0,000 0,37297474 0,37991227 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,3765423 0,3833764 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of defense response GO:0031347 117 84 0,000 0,38008976 0,38681701 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,38008976 0,38664593 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,38361724 0,39006174 ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,38361724 0,38988938 ! regulation of membrane potential GO:0042391 128 85 0,000 0,38361724 0,38971716 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,38361724 0,3895451 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,38712485 0,39293343 ! nucleosome organization GO:0034728 114 87 0,000 0,3906127 0,39629873 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,3906127 0,39612399 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,3906127 0,39594941 ! female pregnancy GO:0007565 130 87 0,000 0,3906127 0,39577499 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,3940809 0,3991132 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,3940809 0,39893753 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,3940809 0,39876202 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of neurogenesis GO:0050767 153 89 0,000 0,39752956 0,40207476 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,39752956 0,40189802 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,39752956 0,40172144 ! regulation of T cell activation GO:0050863 128 89 0,000 0,39752956 0,40154501 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,40095879 0,40483109 ! hormone metabolic process GO:0042445 121 90 0,000 0,40095879 0,40465345 ! RNA localization GO:0006403 135 91 0,000 0,4043687 0,40791579 ! ATP metabolic process GO:0046034 137 91 0,000 0,4043687 0,40773696 ! response to virus GO:0009615 122 91 0,000 0,4043687 0,40755828 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,40775939 0,4107957 ! positive regulation of immune response GO:0050778 121 92 0,000 0,40775939 0,41061585 ! sulfur metabolic process GO:0006790 118 92 0,000 0,40775939 0,41043615 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,41113097 0,41364883 ! electron transport chain GO:0022900 123 94 0,000 0,41448355 0,4168396 ! response to oxidative stress GO:0006979 141 94 0,000 0,41448355 0,41665742 ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,42113213 0,42315592 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,42113213 0,42297114 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,42113213 0,42278652 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,42442834 0,42590977 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,42442834 0,42572403 ! calcium ion transport GO:0006816 167 99 0,000 0,43096513 0,43209232 ! extracellular structure organization GO:0043062 156 99 0,000 0,43096513 0,43190405 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,4342059 0,43496236 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,4342059 0,434773 ! divalent metal ion transport GO:0070838 171 100 0,000 0,4342059 0,4345838 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,4342059 0,43439477 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,4342059 0,4342059