pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1180-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 7,000 1,158E-08 2,786E-05 ! interphase GO:0051325 213 98 7,000 1,483E-08 1,783E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 5,864E-08 4,703E-05 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 7,94E-08 4,776E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 2,182E-07 1,05E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 3,000 5,072E-07 2,034E-04 ! G1 phase GO:0051318 40 19 3,000 1,42E-06 4,882E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 3,827E-06 1,151E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 5,347E-06 1,429E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 2,000 7,254E-06 1,745E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 1,396E-05 3,053E-03 ! androgen receptor signaling pathway GO:0030521 74 36 3,000 2,035E-05 4,08E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 3,092E-05 5,723E-03 ! mesenchymal cell development GO:0014031 87 40 3,000 3,113E-05 5,35E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! gliogenesis GO:0042063 88 41 3,000 3,438E-05 5,514E-03 ! detection of bacterium GO:0016045 18 15 2,000 3,853E-05 5,794E-03 ! epithelial cell differentiation GO:0030855 79 43 3,000 4,16E-05 5,888E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 2,000 4,726E-05 6,317E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 5,72E-05 7,244E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 6,842E-05 8,231E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 9,496E-05 0,01087942 ! response to UV GO:0009411 104 53 3,000 9,535E-05 0,01042819 ! detection of biotic stimulus GO:0009595 29 21 2,000 1,104E-04 0,01155097 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 1,664E-04 0,01668091 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 1,874E-04 0,01803197 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,885E-04 0,01744017 ! meiotic chromosome segregation GO:0045132 7 5 1,000 1,977E-04 0,01761656 ! muscle cell proliferation GO:0033002 11 5 1,000 1,977E-04 0,0169874 ! receptor biosynthetic process GO:0032800 7 5 1,000 1,977E-04 0,01640162 ! glial cell fate commitment GO:0021781 13 5 1,000 1,977E-04 0,0158549 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,977E-04 0,01534345 ! microvillus organization GO:0032528 7 5 1,000 1,977E-04 0,01486397 GO:0030033|microvillus assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 1,977E-04 0,01441355 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 1,977E-04 0,01398962 ! blastocyst development GO:0001824 49 26 2,000 2,123E-04 0,01459747 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,378E-04 0,0158916 ! negative regulation of cell growth GO:0030308 132 67 3,000 2,378E-04 0,0154621 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 2,381E-04 0,01507616 ! fat cell differentiation GO:0045444 50 27 2,000 2,381E-04 0,0146896 ! regulation of chromosome organization GO:0033044 42 27 2,000 2,381E-04 0,01432236 ! negative regulation of kinase activity GO:0033673 131 68 3,000 2,518E-04 0,0147745 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 2,658E-04 0,01522719 ! negative regulation of cell size GO:0045792 134 69 3,000 2,663E-04 0,01490259 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 1,000 2,957E-04 0,01616755 ! establishment of spindle localization GO:0051293 12 6 1,000 2,957E-04 0,01580827 GO:0051653|spindle localization, ! monocyte differentiation GO:0030224 12 6 1,000 2,957E-04 0,01546461 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 2,957E-04 0,01513558 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 2,957E-04 0,01482025 ! negative regulation of transferase activity GO:0051348 140 72 3,000 3,137E-04 0,01540245 ! steroid biosynthetic process GO:0006694 131 76 3,000 3,858E-04 0,01856533 ! prostate gland development GO:0030850 13 7 1,000 4,127E-04 0,01947045 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 4,127E-04 0,01909601 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,127E-04 0,01873571 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,127E-04 0,01838875 ! lipoprotein transport GO:0042953 14 7 1,000 4,127E-04 0,01805441 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 4,127E-04 0,01773201 ! peptidyl-threonine modification GO:0018210 25 7 1,000 4,127E-04 0,01742093 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 4,127E-04 0,01712056 ! negative regulation of organelle organization GO:0010639 161 78 3,000 4,26E-04 0,01737201 ! glial cell differentiation GO:0010001 63 34 2,000 4,761E-04 0,01909111 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 5,487E-04 0,02164096 ! glycine catabolic process GO:0006546 13 8 1,000 5,487E-04 0,02129192 ! ER overload response GO:0006983 12 8 1,000 5,487E-04 0,02095395 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 5,487E-04 0,02062654 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 5,487E-04 0,02030921 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 5,487E-04 0,0200015 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,487E-04 0,01970297 ! blastocyst growth GO:0001832 19 8 1,000 5,487E-04 0,01941322 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 5,487E-04 0,01913187 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 5,487E-04 0,01885856 GO:0000076|DNA replication checkpoint, ! negative regulation of growth GO:0045926 155 84 3,000 5,644E-04 0,01912674 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 6,121E-04 0,02045578 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 7,034E-04 0,02318196 ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 7,034E-04 0,02286869 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 7,034E-04 0,02256377 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 7,034E-04 0,02226688 ! keratinocyte differentiation GO:0030216 62 41 2,000 8,289E-04 0,02590083 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 8,766E-04 0,02704027 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 8,766E-04 0,02669798 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 8,766E-04 0,02636426 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 8,766E-04 0,02603877 ! alpha-beta T cell activation GO:0046631 23 10 1,000 8,766E-04 0,02572123 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 8,766E-04 0,02541133 ! blastocyst formation GO:0001825 17 10 1,000 8,766E-04 0,02510882 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 8,898E-04 0,02518551 ! striated muscle cell differentiation GO:0051146 82 43 2,000 9,534E-04 0,02667231 ! T cell proliferation GO:0042098 26 11 1,000 1,068E-03 0,02954333 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,068E-03 0,02920761 ! melanocyte differentiation GO:0030318 21 11 1,000 1,068E-03 0,02887944 GO:0050931|pigment cell differentiation, ! DNA methylation GO:0006306 19 11 1,000 1,068E-03 0,02855855 GO:0006305|DNA alkylation, ! cardiac cell differentiation GO:0035051 31 11 1,000 1,068E-03 0,02824472 ! lysogeny GO:0030069 21 11 1,000 1,068E-03 0,02793771 GO:0019047|provirus integration, ! regulation of embryonic development GO:0045995 27 11 1,000 1,068E-03 0,02763731 ! cell cycle arrest GO:0007050 213 100 3,000 1,085E-03 0,02778338 ! epidermal cell differentiation GO:0009913 68 46 2,000 1,161E-03 0,02941043 ! pigmentation GO:0043473 100 46 2,000 1,161E-03 0,02910407 ! response to insulin stimulus GO:0032868 95 46 2,000 1,161E-03 0,02880403 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,278E-03 0,03138032 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 1,278E-03 0,03106334 ! histone acetylation GO:0016573 26 12 1,000 1,278E-03 0,03075271 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,278E-03 0,03044823 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,315E-03 0,03100724 ! regulation of gene expression, epigenetic GO:0040029 105 50 2,000 1,48E-03 0,03457021 ! chromatin silencing GO:0006342 26 13 1,000 1,506E-03 0,03484372 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 2,000 1,567E-03 0,03591386 ! covalent chromatin modification GO:0016569 101 52 2,000 1,658E-03 0,03763018 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,752E-03 0,03939537 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,752E-03 0,0390306 ! heart morphogenesis GO:0003007 97 55 2,000 1,949E-03 0,04301864 ! RNA elongation GO:0006354 79 55 2,000 1,949E-03 0,04262756 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 2,016E-03 0,04368966 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 2,016E-03 0,04329958 ! muscle maintenance GO:0046716 26 15 1,000 2,016E-03 0,04291639 ! dopamine metabolic process GO:0042417 35 15 1,000 2,016E-03 0,04253993 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 2,297E-03 0,04805305 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 2,297E-03 0,0476388 ! endothelial cell migration GO:0043542 28 17 1,000 2,595E-03 0,05337234 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 2,595E-03 0,05292003 ! heart looping GO:0001947 30 17 1,000 2,595E-03 0,05247533 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 2,595E-03 0,05203803 ! glycine metabolic process GO:0006544 28 17 1,000 2,595E-03 0,05160797 ! DNA integration GO:0015074 29 17 1,000 2,595E-03 0,05118495 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 1,000 2,595E-03 0,05076881 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 2,595E-03 0,05035939 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,622E-03 0,05046454 ! detection of external stimulus GO:0009581 91 63 2,000 2,874E-03 0,05488174 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,911E-03 0,055154 ! epidermis morphogenesis GO:0048730 40 18 1,000 2,911E-03 0,05472311 ! response to retinoic acid GO:0032526 26 18 1,000 2,911E-03 0,0542989 ! long-chain fatty acid transport GO:0015909 31 18 1,000 2,911E-03 0,05388121 ! myeloid cell differentiation GO:0030099 111 65 2,000 3,141E-03 0,05768637 ! lipid phosphorylation GO:0046834 35 19 1,000 3,244E-03 0,0591341 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 3,244E-03 0,05868949 ! pigmentation during development GO:0048066 41 19 1,000 3,244E-03 0,05825151 ! cellular response to unfolded protein GO:0034620 33 19 1,000 3,244E-03 0,05782001 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 1,000 3,244E-03 0,05739487 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 3,244E-03 0,05697592 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,594E-03 0,06266389 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,594E-03 0,06221307 ! response to vitamin GO:0033273 31 20 1,000 3,594E-03 0,06176869 ! cell cycle checkpoint GO:0000075 137 69 2,000 3,719E-03 0,06345654 ! urogenital system development GO:0001655 137 69 2,000 3,719E-03 0,06300967 ! hindlimb morphogenesis GO:0035137 43 21 1,000 3,961E-03 0,06664284 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 3,961E-03 0,06618004 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 3,961E-03 0,06572363 ! DNA modification GO:0006304 34 21 1,000 3,961E-03 0,06527347 ! response to cytokine stimulus GO:0034097 63 21 1,000 3,961E-03 0,06482943 ! reproductive structure development GO:0048608 113 71 2,000 4,03E-03 0,06552157 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 4,344E-03 0,07014938 GO:0060415|muscle tissue morphogenesis, ! positive regulation of intracellular transport GO:0032388 37 22 1,000 4,344E-03 0,06968172 ! positive regulation of B cell activation GO:0050871 38 22 1,000 4,344E-03 0,06922025 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 4,344E-03 0,06876485 ! eye development GO:0001654 143 74 2,000 4,527E-03 0,07118773 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,744E-03 0,07411844 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 4,744E-03 0,07364026 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 4,744E-03 0,0731682 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 4,744E-03 0,07270216 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,744E-03 0,07224202 ! barbed-end actin filament capping GO:0051016 50 23 1,000 4,744E-03 0,07178767 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 1,000 4,744E-03 0,071339 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,744E-03 0,0708959 ! fatty acid transport GO:0015908 44 23 1,000 4,744E-03 0,07045827 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 5,16E-03 0,07616873 ! lymphocyte proliferation GO:0046651 48 24 1,000 5,16E-03 0,07570429 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 5,244E-03 0,07646932 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,593E-03 0,08105833 ! vasculogenesis GO:0001570 46 25 1,000 5,593E-03 0,08057295 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 5,593E-03 0,08009335 ! negative regulation of DNA replication GO:0008156 42 25 1,000 5,593E-03 0,07961942 ! receptor metabolic process GO:0043112 46 25 1,000 5,593E-03 0,07915107 ! somitogenesis GO:0001756 43 25 1,000 5,593E-03 0,0786882 ! muscle cell differentiation GO:0042692 159 80 2,000 5,627E-03 0,07871158 ! T cell activation GO:0042110 168 81 2,000 5,824E-03 0,08100343 ! response to nutrient GO:0007584 125 82 2,000 6,026E-03 0,08332577 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 6,026E-03 0,08284963 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 6,041E-03 0,08258189 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 6,041E-03 0,08211533 ! initiation of viral infection GO:0019059 57 26 1,000 6,041E-03 0,081654 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 6,041E-03 0,08119784 ! positive regulation of nuclear division GO:0051785 40 26 1,000 6,041E-03 0,08074674 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 6,041E-03 0,08030062 ! leukocyte proliferation GO:0070661 52 26 1,000 6,041E-03 0,07985941 GO:0032943|mononuclear cell proliferation, ! protein amino acid acylation GO:0043543 55 27 1,000 6,505E-03 0,08552642 ! male gonad development GO:0008584 44 27 1,000 6,505E-03 0,0850616 ! response to toxin GO:0009636 47 27 1,000 6,505E-03 0,08460181 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 6,505E-03 0,08414696 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 6,985E-03 0,08987213 ! negative regulation of protein modification process GO:0031400 60 28 1,000 6,985E-03 0,08939408 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 6,985E-03 0,0889211 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 6,985E-03 0,08845309 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 7,481E-03 0,09423202 ! catechol metabolic process GO:0009712 54 29 1,000 7,481E-03 0,09374123 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! cell fate determination GO:0001709 60 29 1,000 7,481E-03 0,09325552 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 7,481E-03 0,09277483 ! regulation of cell adhesion GO:0030155 212 89 2,000 7,554E-03 0,09320767 ! regulation of cell cycle process GO:0010564 149 90 2,000 7,789E-03 0,09561988 ! sex differentiation GO:0007548 145 90 2,000 7,789E-03 0,0951345 ! phenol metabolic process GO:0018958 55 30 1,000 7,992E-03 0,09710942 ! regulation of B cell activation GO:0050864 50 30 1,000 7,992E-03 0,09662144 ! erythrocyte differentiation GO:0030218 55 31 1,000 8,518E-03 0,10246893 ! natural killer cell activation GO:0030101 45 31 1,000 8,518E-03 0,10195913 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 8,518E-03 0,10145438 ! transcription initiation GO:0006352 153 94 2,000 8,774E-03 0,10398568 ! spindle organization GO:0007051 46 32 1,000 9,059E-03 0,10684473 ! metanephros development GO:0001656 74 32 1,000 9,059E-03 0,10632354 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 9,059E-03 0,1058074 ! hindbrain development GO:0030902 61 32 1,000 9,059E-03 0,10529626 ! gene silencing GO:0016458 65 32 1,000 9,059E-03 0,10479003 ! leukocyte differentiation GO:0002521 202 96 2,000 9,292E-03 0,1069646 ! detection of stimulus GO:0051606 151 96 2,000 9,292E-03 0,10645525 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 9,616E-03 0,10964426 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01018673 0,11560981 ! placenta development GO:0001890 53 34 1,000 0,01018673 0,11506704 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01077266 0,12111686 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01137314 0,12727341 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01137314 0,12668419 ! meiosis I GO:0007127 65 37 1,000 0,01198806 0,13291829 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01198806 0,13230857 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01198806 0,13170442 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,01261726 0,13798693 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 1,000 0,01261726 0,13736256 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01261726 0,13674381 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01261726 0,13613061 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,01261726 0,13552288 GO:0006073|cellular glucan metabolic process, ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01326061 0,1418001 ! segmentation GO:0035282 67 39 1,000 0,01326061 0,14117267 ! cytokinesis GO:0000910 72 40 1,000 0,01391797 0,14751819 ! T cell differentiation GO:0030217 81 41 1,000 0,0145892 0,15395447 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01527417 0,16047887 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01527417 0,15978113 ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,01527417 0,15908944 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01527417 0,15840371 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01597275 0,16493748 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01597275 0,16423262 ! male sex differentiation GO:0046661 76 44 1,000 0,01668479 0,17082389 ! biopolymer methylation GO:0043414 84 44 1,000 0,01668479 0,17010006 ! developmental growth GO:0048589 82 44 1,000 0,01668479 0,16938234 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,01741018 0,17600371 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,01741018 0,1752673 ! cell growth GO:0016049 84 45 1,000 0,01741018 0,17453702 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01814876 0,18118641 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01814876 0,18043771 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01814876 0,17969516 ! response to calcium ion GO:0051592 81 47 1,000 0,01890042 0,18637058 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01890042 0,18560988 ! JNK cascade GO:0007254 91 47 1,000 0,01890042 0,18485537 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01890042 0,18410697 ! methylation GO:0032259 90 47 1,000 0,01890042 0,1833646 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,01966503 0,1900163 ! activation of caspase activity GO:0006919 84 48 1,000 0,01966503 0,18925624 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01966503 0,18850223 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02044245 0,1951767 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,02044245 0,19440525 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,02044245 0,19363988 ! regulation of ossification GO:0030278 117 50 1,000 0,02123255 0,20033537 ! histone modification GO:0016570 91 50 1,000 0,02123255 0,19955281 ! positive regulation of binding GO:0051099 78 51 1,000 0,02203521 0,20629077 ! viral infectious cycle GO:0019058 99 51 1,000 0,02203521 0,20549119 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,02203521 0,20469779 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,02203521 0,20391049 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02221402 0,20477753 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02221402 0,20399594 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02221402 0,20322029 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02221402 0,20245052 ! neuron fate determination GO:0048664 7 5 0,000 0,02221402 0,20168655 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02221402 0,20092833 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02221402 0,20017579 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02221402 0,19942887 ! polyol transport GO:0015791 12 5 0,000 0,02221402 0,1986875 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02221402 0,19795162 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02221402 0,19722117 ! response to superoxide GO:0000303 10 5 0,000 0,02221402 0,19649609 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02221402 0,19577632 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02221402 0,19506181 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02221402 0,1943525 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02221402 0,19364832 ! female meiosis GO:0007143 7 5 0,000 0,02221402 0,19294923 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02221402 0,19225517 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02221402 0,19156608 ! cobalt ion transport GO:0006824 11 5 0,000 0,02221402 0,19088192 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02221402 0,19020262 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02221402 0,18952814 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02221402 0,18885843 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02221402 0,18819344 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02221402 0,18753311 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02221402 0,1868774 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02221402 0,18622626 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02221402 0,18557964 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02221402 0,1849375 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02221402 0,18429978 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02221402 0,18366645 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02221402 0,18303745 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02221402 0,18241275 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02221402 0,1817923 ! negative chemotaxis GO:0050919 14 5 0,000 0,02221402 0,18117606 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02221402 0,18056398 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02221402 0,17995602 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02221402 0,17935214 ! behavioral response to pain GO:0048266 9 5 0,000 0,02221402 0,1787523 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02221402 0,17815646 ! Notch receptor processing GO:0007220 8 5 0,000 0,02221402 0,17756457 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02221402 0,17697661 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02221402 0,17639253 ! micturition GO:0060073 9 5 0,000 0,02221402 0,17581229 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02221402 0,17523586 ! copulation GO:0007620 9 5 0,000 0,02221402 0,17466319 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02221402 0,17409426 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02221402 0,17352901 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02221402 0,17296743 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02221402 0,17240947 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02221402 0,1718551 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02221402 0,17130428 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02221402 0,17075699 ! grooming behavior GO:0007625 6 5 0,000 0,02221402 0,17021317 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02221402 0,16967281 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02221402 0,16913588 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02221402 0,16860232 ! response to protozoan GO:0001562 10 5 0,000 0,02221402 0,16807213 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02221402 0,16754526 ! lymph vessel development GO:0001945 10 5 0,000 0,02221402 0,16702168 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02221402 0,16650136 ! endochondral ossification GO:0001958 16 5 0,000 0,02221402 0,16598428 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02221402 0,16547039 ! parathyroid gland development GO:0060017 13 5 0,000 0,02221402 0,16495968 ! anagen GO:0042640 6 5 0,000 0,02221402 0,16445211 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02221402 0,16394766 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02221402 0,16344629 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02221402 0,16294798 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02221402 0,16245269 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02221402 0,16196041 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02221402 0,16147111 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02221402 0,16098475 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02221402 0,16050131 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02221402 0,16002077 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02221402 0,15954309 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02221402 0,15906826 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02221402 0,15859625 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02221402 0,15812703 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02221402 0,15766058 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02221402 0,15719687 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02221402 0,15673588 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02221402 0,15627759 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02221402 0,15582197 ! histidine catabolic process GO:0006548 6 5 0,000 0,02221402 0,155369 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02221402 0,15491866 ! valine metabolic process GO:0006573 10 5 0,000 0,02221402 0,15447092 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02221402 0,15402575 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02221402 0,15358315 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02221402 0,15314308 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02221402 0,15270553 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02221402 0,15227047 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02221402 0,15183789 ! polyol catabolic process GO:0046174 7 5 0,000 0,02221402 0,15140775 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02221402 0,15098005 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02221402 0,15055475 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02221402 0,15013184 ! muscle cell migration GO:0014812 8 5 0,000 0,02221402 0,14971131 ! mitochondrial fission GO:0000266 8 5 0,000 0,02221402 0,14929312 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02221402 0,14887726 ! mRNA transcription GO:0009299 9 5 0,000 0,02221402 0,14846371 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02221402 0,14805246 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02221402 0,14764347 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02221402 0,14723674 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02221402 0,14683224 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02221402 0,14642996 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02221402 0,14602988 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02221402 0,14563198 ! response to food GO:0032094 6 5 0,000 0,02221402 0,14523624 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02221402 0,14484265 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02221402 0,14445118 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02221402 0,14406182 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02221402 0,14367456 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02221402 0,14328937 ! forebrain neuron development GO:0021884 13 5 0,000 0,02221402 0,14290625 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02221402 0,14252516 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02221402 0,14214611 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02221402 0,14176906 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02221402 0,14139401 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02221402 0,14102094 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02221402 0,14064983 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02221402 0,14028067 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02221402 0,13991345 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02221402 0,13954814 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02221402 0,13918473 ! basic amino acid transport GO:0015802 11 5 0,000 0,02221402 0,13882321 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02221402 0,13846357 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02221402 0,13810578 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02221402 0,13774984 ! depyrimidination GO:0045008 10 5 0,000 0,02221402 0,13739572 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02221402 0,13704343 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02221402 0,13669293 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02221402 0,13634423 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02221402 0,13599729 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02221402 0,13565212 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02221402 0,1353087 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02221402 0,13496701 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02221402 0,13462704 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02221402 0,13428879 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02221402 0,13395222 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02221402 0,13361734 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02221402 0,13328413 ! response to arsenic GO:0046685 10 5 0,000 0,02221402 0,13295258 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02221402 0,13262267 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02221402 0,1322944 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02221402 0,13196774 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02221402 0,1316427 ! response to cadmium ion GO:0046686 7 5 0,000 0,02221402 0,13131925 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02221402 0,13099739 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02221402 0,13067711 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02221402 0,13035838 ! decidualization GO:0046697 11 5 0,000 0,02221402 0,13004121 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02221402 0,12972557 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02221402 0,12941147 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02221402 0,12909888 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02221402 0,1287878 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02221402 0,12847821 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02221402 0,12817011 ! neural tube patterning GO:0021532 7 5 0,000 0,02221402 0,12786348 ! embryonic cleavage GO:0040016 6 5 0,000 0,02221402 0,12755832 ! peroxisome fission GO:0016559 5 5 0,000 0,02221402 0,12725461 ! histone demethylation GO:0016577 10 5 0,000 0,02221402 0,12695234 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02221402 0,12665151 ! mitotic recombination GO:0006312 9 5 0,000 0,02221402 0,1263521 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02221402 0,1260541 ! metaphase plate congression GO:0051310 7 5 0,000 0,02221402 0,1257575 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02221402 0,12546229 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02221402 0,12516847 ! enteric nervous system development GO:0048484 8 5 0,000 0,02221402 0,12487602 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02221402 0,12458493 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02221402 0,1242952 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02221402 0,12400681 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02221402 0,12371976 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02221402 0,12343403 ! plasminogen activation GO:0031639 5 5 0,000 0,02221402 0,12314962 ! B cell homeostasis GO:0001782 13 5 0,000 0,02221402 0,12286652 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02221402 0,12258472 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02221402 0,1223042 ! metaphase GO:0051323 8 5 0,000 0,02221402 0,12202497 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02221402 0,12174701 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02221402 0,12147031 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02221402 0,12119487 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02221402 0,12092067 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02221402 0,12064771 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02221402 0,12037598 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02221402 0,12010548 ! response to redox state GO:0051775 5 5 0,000 0,02221402 0,11983618 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02221402 0,11956809 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02221402 0,1193012 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02221402 0,11903549 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02221402 0,11877097 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02221402 0,11850762 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02221402 0,11824543 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02221402 0,11798441 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02221402 0,11772453 ! striatum development GO:0021756 9 5 0,000 0,02221402 0,11746579 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02221402 0,11720819 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02221402 0,11695172 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02221402 0,11669637 ! glial cell migration GO:0008347 11 5 0,000 0,02221402 0,11644213 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02221402 0,11618899 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02221402 0,11593696 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02221402 0,11568601 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02221402 0,11543615 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02221402 0,11518736 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02221402 0,11493965 ! neuroprotection GO:0043526 6 5 0,000 0,02221402 0,114693 ! neural plate development GO:0001840 8 5 0,000 0,02221402 0,1144474 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02221402 0,11420286 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02221402 0,11395935 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02221402 0,11371689 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02221402 0,11347545 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02221402 0,11323504 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02221402 0,11299564 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02221402 0,11275725 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02221402 0,11251987 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02221402 0,11228348 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02221402 0,11204809 ! spindle assembly GO:0051225 6 5 0,000 0,02221402 0,11181367 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02221402 0,11158024 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02221402 0,11134778 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 6 5 0,000 0,02221402 0,11111629 ! stem cell division GO:0017145 11 5 0,000 0,02221402 0,11088576 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02221402 0,11065618 ! organ regeneration GO:0031100 7 5 0,000 0,02221402 0,11042755 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02221402 0,11019987 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02221402 0,10997312 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02221402 0,1097473 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,02285031 0,11265952 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,02367771 0,11650014 ! cell maturation GO:0048469 100 53 1,000 0,02367771 0,11626239 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,02367771 0,1160256 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,02451729 0,11989553 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,02536893 0,1238086 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02536893 0,12355798 ! aging GO:0007568 103 55 1,000 0,02536893 0,12330837 ! regulation of actin filament length GO:0030832 105 56 1,000 0,0262325 0,12724878 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,0262325 0,12699274 ! regulation of DNA replication GO:0006275 101 56 1,000 0,0262325 0,12673774 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,0262325 0,12648375 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02659769 0,1279881 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02659769 0,12773263 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02659769 0,12747819 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02659769 0,12722475 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02659769 0,12697232 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02659769 0,12672089 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02659769 0,12647045 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02659769 0,126221 ! sleep GO:0030431 13 6 0,000 0,02659769 0,12597254 ! response to oxygen radical GO:0000305 11 6 0,000 0,02659769 0,12572505 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02659769 0,12547853 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02659769 0,12523297 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02659769 0,12498838 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02659769 0,12474474 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02659769 0,12450204 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02659769 0,12426029 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02659769 0,12401948 ! forebrain regionalization GO:0021871 8 6 0,000 0,02659769 0,12377959 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02659769 0,12354064 ! male meiosis GO:0007140 7 6 0,000 0,02659769 0,1233026 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02659769 0,12306548 ! response to zinc ion GO:0010043 9 6 0,000 0,02659769 0,12282927 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02659769 0,12259396 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02659769 0,12235956 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02659769 0,12212605 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02659769 0,12189343 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02659769 0,12166169 ! malate metabolic process GO:0006108 11 6 0,000 0,02659769 0,12143083 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02659769 0,12120085 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02659769 0,12097174 ! protein refolding GO:0042026 15 6 0,000 0,02659769 0,12074349 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02659769 0,1205161 ! opsonization GO:0008228 8 6 0,000 0,02659769 0,12028957 ! mating behavior GO:0007617 7 6 0,000 0,02659769 0,12006388 ! neuron remodeling GO:0016322 15 6 0,000 0,02659769 0,11983904 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02659769 0,11961505 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02659769 0,11939188 ! equilibrioception GO:0050957 14 6 0,000 0,02659769 0,11916955 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02659769 0,11894805 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02659769 0,11872736 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02659769 0,1185075 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02659769 0,11828845 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02659769 0,1180702 ! toxin metabolic process GO:0009404 11 6 0,000 0,02659769 0,11785276 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02659769 0,11763612 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02659769 0,11742027 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02659769 0,11720522 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02659769 0,11699095 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02659769 0,11677746 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02659769 0,11656475 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02659769 0,11635282 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02659769 0,11614165 ! thymic T cell selection GO:0045061 12 6 0,000 0,02659769 0,11593125 ! protein lipoylation GO:0009249 10 6 0,000 0,02659769 0,11572161 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02659769 0,11551272 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02659769 0,11530459 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02659769 0,11509721 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02659769 0,11489057 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02659769 0,11468468 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02659769 0,11447952 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02659769 0,11427509 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02659769 0,11407139 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02659769 0,11386842 ! hyperosmotic response GO:0006972 9 6 0,000 0,02659769 0,11366616 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02659769 0,11346463 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02659769 0,1132638 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02659769 0,11306369 ! urea metabolic process GO:0019627 7 6 0,000 0,02659769 0,11286428 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02659769 0,11266558 ! neutrophil activation GO:0042119 8 6 0,000 0,02659769 0,11246757 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02659769 0,11227026 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02659769 0,11207364 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02659769 0,11187771 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02659769 0,11168246 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02659769 0,11148789 ! neuron apoptosis GO:0051402 9 6 0,000 0,02659769 0,111294 ! nucleoside salvage GO:0043174 9 6 0,000 0,02659769 0,11110078 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02659769 0,11090823 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02659769 0,11071635 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02659769 0,11052513 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02659769 0,11033457 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02659769 0,11014466 ! carnitine transport GO:0015879 10 6 0,000 0,02659769 0,10995541 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02659769 0,10976681 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02659769 0,10957885 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02659769 0,10939154 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02659769 0,10920486 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02659769 0,10901882 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02659769 0,10883342 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02659769 0,10864864 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02659769 0,10846449 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02659769 0,10828096 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02659769 0,10809806 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02659769 0,10791577 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 0,000 0,02659769 0,10773409 ! response to UV-C GO:0010225 11 6 0,000 0,02659769 0,10755302 ! astrocyte development GO:0014002 15 6 0,000 0,02659769 0,10737257 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02659769 0,10719271 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02659769 0,10701346 ! interaction with symbiont GO:0051702 13 6 0,000 0,02659769 0,10683481 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02659769 0,10665675 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02659769 0,10647928 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02659769 0,10630241 ! response to copper ion GO:0046688 10 6 0,000 0,02659769 0,10612612 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02659769 0,10595041 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02659769 0,10577529 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02659769 0,10560074 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02659769 0,10542677 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02659769 0,10525337 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02659769 0,10508054 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02659769 0,10490828 ! hair follicle maturation GO:0048820 7 6 0,000 0,02659769 0,10473658 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02659769 0,10456544 ! Schwann cell development GO:0014044 15 6 0,000 0,02659769 0,10439486 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02659769 0,10422484 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02659769 0,10405537 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02659769 0,10388644 ! subpallium development GO:0021544 10 6 0,000 0,02659769 0,10371807 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02659769 0,10355024 ! histone ubiquitination GO:0016574 8 6 0,000 0,02659769 0,10338296 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02659769 0,10321621 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02659769 0,10305 ! G2 phase GO:0051319 16 6 0,000 0,02659769 0,10288432 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02659769 0,10271918 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02659769 0,10255457 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02659769 0,10239048 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02659769 0,10222692 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02659769 0,10206387 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02659769 0,10190135 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02659769 0,10173935 ! receptor internalization GO:0031623 10 6 0,000 0,02659769 0,10157786 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02659769 0,10141688 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02659769 0,10125641 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02659769 0,10109644 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02659769 0,10093699 ! protein deubiquitination GO:0016579 14 6 0,000 0,02659769 0,10077803 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02659769 0,10061957 ! protein destabilization GO:0031648 9 6 0,000 0,02659769 0,10046162 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02659769 0,10030415 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02659769 0,10014718 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02659769 0,0999907 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02659769 0,09983471 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02659769 0,0996792 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02659769 0,09952418 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02659769 0,09936964 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02659769 0,09921558 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02659769 0,099062 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02659769 0,09890889 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02659769 0,09875625 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02659769 0,09860408 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02659769 0,09845238 ! catecholamine transport GO:0051937 9 6 0,000 0,02659769 0,09830115 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02659769 0,09815038 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02659769 0,09800008 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02659769 0,09785023 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02659769 0,09770084 ! maternal placenta development GO:0001893 12 6 0,000 0,02659769 0,0975519 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02659769 0,09740342 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02659769 0,09725539 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02659769 0,09710781 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02659769 0,09696068 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02659769 0,09681399 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02659769 0,09666775 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02659769 0,09652194 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,02710788 0,09822525 ! lipid modification GO:0030258 97 57 1,000 0,02710788 0,09807754 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02710788 0,09793027 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,02799495 0,1009833 ! regulation of cellular component size GO:0032535 109 59 1,000 0,02889359 0,10406884 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02889359 0,10391328 ! DNA catabolic process GO:0006308 86 59 1,000 0,02889359 0,10375819 ! establishment of organelle localization GO:0051656 109 59 1,000 0,02889359 0,10360356 ! regulation of heart contraction GO:0008016 110 60 1,000 0,02980368 0,10670783 ! camera-type eye development GO:0043010 116 60 1,000 0,02980368 0,10654928 ! kidney development GO:0001822 122 60 1,000 0,02980368 0,10639119 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,0307251 0,10951792 ! tRNA transcription GO:0009304 14 7 0,000 0,03096186 0,11019856 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03096186 0,11003578 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03096186 0,10987349 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03096186 0,10971167 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03096186 0,10955033 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03096186 0,10938946 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03096186 0,10922907 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03096186 0,10906914 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03096186 0,10890969 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03096186 0,10875069 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03096186 0,10859217 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03096186 0,1084341 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03096186 0,10827649 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03096186 0,10811934 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03096186 0,10796265 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03096186 0,1078064 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03096186 0,10765062 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03096186 0,10749528 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03096186 0,10734038 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03096186 0,10718594 ! glycolipid transport GO:0046836 10 7 0,000 0,03096186 0,10703193 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03096186 0,10687837 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03096186 0,10672525 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03096186 0,10657257 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03096186 0,10642032 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03096186 0,10626851 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03096186 0,10611713 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03096186 0,10596618 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03096186 0,10581566 ! mRNA stabilization GO:0048255 18 7 0,000 0,03096186 0,10566557 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03096186 0,1055159 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03096186 0,10536666 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03096186 0,10521783 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03096186 0,10506943 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03096186 0,10492144 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03096186 0,10477388 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03096186 0,10462672 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03096186 0,10447998 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03096186 0,10433365 ! rhythmic behavior GO:0007622 15 7 0,000 0,03096186 0,10418773 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03096186 0,10404221 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03096186 0,10389711 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03096186 0,1037524 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03096186 0,1036081 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03096186 0,1034642 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03096186 0,1033207 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03096186 0,1031776 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03096186 0,10303489 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03096186 0,10289258 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03096186 0,10275066 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03096186 0,10260913 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03096186 0,10246799 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03096186 0,10232723 ! spinal cord patterning GO:0021511 13 7 0,000 0,03096186 0,10218687 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03096186 0,10204688 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03096186 0,10190729 ! adrenal gland development GO:0030325 17 7 0,000 0,03096186 0,10176807 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03096186 0,10162923 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03096186 0,10149077 ! ovulation GO:0030728 9 7 0,000 0,03096186 0,10135269 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03096186 0,10121498 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03096186 0,10107765 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03096186 0,10094069 ! microtubule nucleation GO:0007020 20 7 0,000 0,03096186 0,10080409 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03096186 0,10066787 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03096186 0,10053202 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03096186 0,10039653 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03096186 0,10026141 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03096186 0,10012665 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03096186 0,09999225 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03096186 0,09985821 ! galactose metabolic process GO:0006012 13 7 0,000 0,03096186 0,09972453 ! vesicle fusion GO:0006906 17 7 0,000 0,03096186 0,09959121 ! response to dietary excess GO:0002021 8 7 0,000 0,03096186 0,09945825 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03096186 0,09932563 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03096186 0,09919338 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03096186 0,09906147 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03096186 0,09892991 ! organ growth GO:0035265 15 7 0,000 0,03096186 0,09879871 ! purine salvage GO:0043101 10 7 0,000 0,03096186 0,09866785 ! nucleoside transport GO:0015858 8 7 0,000 0,03096186 0,09853734 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03096186 0,09840717 ! parturition GO:0007567 14 7 0,000 0,03096186 0,09827734 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03096186 0,09814786 ! rRNA modification GO:0000154 14 7 0,000 0,03096186 0,09801872 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03096186 0,09788992 ! spindle checkpoint GO:0031577 15 7 0,000 0,03096186 0,09776145 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03096186 0,09763332 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03096186 0,09750553 ! macrophage differentiation GO:0030225 11 7 0,000 0,03096186 0,09737807 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03096186 0,09725095 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03096186 0,09712415 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03096186 0,09699769 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03096186 0,09687155 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03096186 0,09674575 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03096186 0,09662027 ! fibrinolysis GO:0042730 10 7 0,000 0,03096186 0,09649511 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03096186 0,09637028 ! eating behavior GO:0042755 7 7 0,000 0,03096186 0,09624577 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03096186 0,09612158 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03096186 0,09599771 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03096186 0,09587416 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03096186 0,09575093 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03096186 0,09562802 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03096186 0,09550542 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03096186 0,09538313 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03096186 0,09526116 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03096186 0,0951395 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03096186 0,09501814 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03096186 0,0948971 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03096186 0,09477637 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03096186 0,09465594 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03096186 0,09453582 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03096186 0,094416 ! regulation of meiosis GO:0040020 12 7 0,000 0,03096186 0,09429649 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03096186 0,09417728 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03096186 0,09405837 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03096186 0,09393975 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03096186 0,09382144 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03096186 0,09370343 ! transcription termination GO:0006353 13 7 0,000 0,03096186 0,09358571 ! response to tumor cell GO:0002347 13 7 0,000 0,03096186 0,09346829 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03096186 0,09335116 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03096186 0,09323432 ! anaphase GO:0051322 17 7 0,000 0,03096186 0,09311778 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03096186 0,09300153 ! axonal fasciculation GO:0007413 18 7 0,000 0,03096186 0,09288557 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03096186 0,09276989 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03096186 0,09265451 ! diuresis GO:0030146 12 7 0,000 0,03096186 0,09253941 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03096186 0,0924246 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03096186 0,09231007 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03096186 0,09219582 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03096186 0,09208186 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03096186 0,09196818 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03096186 0,09185478 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03096186 0,09174166 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03096186 0,09162881 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03096186 0,09151625 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03096186 0,09140396 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03096186 0,09129194 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03096186 0,0911802 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03096186 0,09106874 ! lymph node development GO:0048535 10 7 0,000 0,03096186 0,09095754 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03096186 0,09084662 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03096186 0,09073596 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03096186 0,09062558 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03096186 0,09051546 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03096186 0,09040561 ! adult feeding behavior GO:0008343 9 7 0,000 0,03096186 0,09029603 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03096186 0,09018671 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03096186 0,09007766 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03096186 0,08996887 ! muscle adaptation GO:0043500 14 7 0,000 0,03096186 0,08986034 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03096186 0,08975208 ! retina homeostasis GO:0001895 12 7 0,000 0,03096186 0,08964407 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03096186 0,08953633 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03096186 0,08942884 ! protein prenylation GO:0018342 18 7 0,000 0,03096186 0,08932161 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03096186 0,08921464 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03096186 0,08910793 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03096186 0,08900146 ! viral reproductive process GO:0022415 126 62 1,000 0,03165773 0,09089321 ! gonad development GO:0008406 98 62 1,000 0,03165773 0,09078487 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,03165773 0,0906768 ! regulation of mitosis GO:0007088 105 63 1,000 0,03260146 0,09326886 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,03260146 0,09315809 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,03260146 0,09304758 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,03452173 0,09841147 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,03452173 0,098295 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0353066 0,10041096 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0353066 0,10029241 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0353066 0,10017414 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0353066 0,10005615 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0353066 0,09993844 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0353066 0,099821 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0353066 0,09970384 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0353066 0,09958695 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0353066 0,09947034 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0353066 0,099354 ! meiotic prophase I GO:0007128 13 8 0,000 0,0353066 0,09923793 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0353066 0,09912214 ! oligopeptide transport GO:0006857 15 8 0,000 0,0353066 0,09900661 ! UTP metabolic process GO:0046051 8 8 0,000 0,0353066 0,09889135 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0353066 0,09877636 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0353066 0,09866164 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0353066 0,09854718 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0353066 0,09843299 ! succinate metabolic process GO:0006105 14 8 0,000 0,0353066 0,09831907 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0353066 0,0982054 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0353066 0,098092 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0353066 0,09797886 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0353066 0,09786598 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0353066 0,09775336 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0353066 0,097641 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0353066 0,0975289 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0353066 0,09741706 ! reflex GO:0060004 16 8 0,000 0,0353066 0,09730547 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0353066 0,09719413 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0353066 0,09708305 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0353066 0,09697223 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0353066 0,09686166 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0353066 0,09675134 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0353066 0,09664127 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0353066 0,09653145 ! pigment granule organization GO:0048753 16 8 0,000 0,0353066 0,09642188 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0353066 0,09631255 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0353066 0,09620348 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0353066 0,09609465 ! histidine metabolic process GO:0006547 16 8 0,000 0,0353066 0,09598607 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0353066 0,09587773 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0353066 0,09576964 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0353066 0,09566179 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0353066 0,09555419 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0353066 0,09544682 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0353066 0,0953397 ! melanin metabolic process GO:0006582 15 8 0,000 0,0353066 0,09523282 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0353066 0,09512617 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0353066 0,09501977 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0353066 0,0949136 ! macrophage activation GO:0042116 12 8 0,000 0,0353066 0,09480767 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0353066 0,09470198 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0353066 0,09459652 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0353066 0,09449129 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0353066 0,0943863 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0353066 0,09428155 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0353066 0,09417702 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0353066 0,09407273 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0353066 0,09396866 ! osteoblast development GO:0002076 16 8 0,000 0,0353066 0,09386483 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0353066 0,09376123 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0353066 0,09365785 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0353066 0,09355471 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0353066 0,09345178 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0353066 0,09334909 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0353066 0,09324662 ! response to UV-B GO:0010224 16 8 0,000 0,0353066 0,09314438 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0353066 0,09304236 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0353066 0,09294056 ! intermediate filament organization GO:0045109 12 8 0,000 0,0353066 0,09283899 ! cellular extravasation GO:0045123 12 8 0,000 0,0353066 0,09273763 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0353066 0,0926365 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0353066 0,09253559 ! response to antibiotic GO:0046677 11 8 0,000 0,0353066 0,0924349 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0353066 0,09233443 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0353066 0,09223417 ! DNA topological change GO:0006265 12 8 0,000 0,0353066 0,09213413 ! response to tropane GO:0014073 15 8 0,000 0,0353066 0,09203431 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0353066 0,09193471 ! melanosome transport GO:0032402 13 8 0,000 0,0353066 0,09183532 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0353066 0,09173615 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0353066 0,09163719 ! mast cell activation GO:0045576 14 8 0,000 0,0353066 0,09153844 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0353066 0,09143991 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0353066 0,09134158 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0353066 0,09124347 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0353066 0,09114557 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0353066 0,09104788 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0353066 0,0909504 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0353066 0,09085313 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0353066 0,09075606 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0353066 0,0906592 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0353066 0,09056255 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0353066 0,0904661 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0353066 0,09036986 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0353066 0,09027383 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0353066 0,090178 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0353066 0,09008237 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0353066 0,08998694 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0353066 0,08989172 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0353066 0,08979669 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0353066 0,08970187 ! hormone catabolic process GO:0042447 17 8 0,000 0,0353066 0,08960725 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0353066 0,08951283 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0353066 0,0894186 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0353066 0,08932458 ! ATP catabolic process GO:0006200 11 8 0,000 0,0353066 0,08923075 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0353066 0,08913712 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0353066 0,08904368 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0353066 0,08895044 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0353066 0,0888574 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0353066 0,08876455 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0353066 0,08867189 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0353066 0,08857943 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0353066 0,08848716 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0353066 0,08839508 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0353066 0,08830319 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0353066 0,0882115 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0353066 0,08811999 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0353066 0,08802868 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0353066 0,08793755 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0353066 0,08784661 ! developmental maturation GO:0021700 116 66 1,000 0,03549804 0,0882317 ! cell projection assembly GO:0030031 120 66 1,000 0,03549804 0,08814065 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,03648499 0,09049781 ! lung development GO:0030324 144 67 1,000 0,03648499 0,09040461 ! chromosome segregation GO:0007059 113 67 1,000 0,03648499 0,0903116 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,03648499 0,09021878 ! viral reproduction GO:0016032 134 68 1,000 0,03748245 0,09259012 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,03849032 0,09498227 ! antigen processing and presentation GO:0019882 104 69 1,000 0,03849032 0,09488495 ! appendage morphogenesis GO:0035107 135 70 1,000 0,03950849 0,09729521 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,03950849 0,09719572 ! regulation of developmental growth GO:0048638 15 9 0,000 0,039632 0,0974 ! axon extension GO:0048675 15 9 0,000 0,039632 0,09730061 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,039632 0,09720142 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,039632 0,09710244 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,039632 0,09700366 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,039632 0,09690508 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,039632 0,0968067 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,039632 0,09670852 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,039632 0,09661053 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,039632 0,09651275 ! phosphate transport GO:0006817 19 9 0,000 0,039632 0,09641516 ! reproductive behavior GO:0019098 19 9 0,000 0,039632 0,09631777 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,039632 0,09622058 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,039632 0,09612358 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,039632 0,09602678 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,039632 0,09593018 ! GTP metabolic process GO:0046039 9 9 0,000 0,039632 0,09583376 ! RNA methylation GO:0001510 15 9 0,000 0,039632 0,09573755 ! elastic fiber assembly GO:0048251 15 9 0,000 0,039632 0,09564152 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,039632 0,09554569 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,039632 0,09545005 ! artery development GO:0060840 24 9 0,000 0,039632 0,0953546 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,039632 0,09525934 ! regulation of glycolysis GO:0006110 21 9 0,000 0,039632 0,09516427 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,039632 0,09506939 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,039632 0,0949747 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,039632 0,09488019 ! chemosensory behavior GO:0007635 20 9 0,000 0,039632 0,09478588 ! microtubule bundle formation GO:0001578 21 9 0,000 0,039632 0,09469175 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,039632 0,09459781 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,039632 0,09450406 ! leukocyte degranulation GO:0043299 16 9 0,000 0,039632 0,09441049 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,039632 0,09431711 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,039632 0,09422391 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,039632 0,09413089 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,039632 0,09403806 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,039632 0,09394541 ! protein targeting to ER GO:0045047 22 9 0,000 0,039632 0,09385295 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,039632 0,09376066 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,039632 0,09366856 ! T cell selection GO:0045058 23 9 0,000 0,039632 0,09357664 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,039632 0,0934849 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,039632 0,09339334 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,039632 0,09330195 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,039632 0,09321075 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,039632 0,09311972 ! mannose metabolic process GO:0006013 13 9 0,000 0,039632 0,09302887 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,039632 0,0929382 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,039632 0,09284771 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,039632 0,09275739 ! receptor clustering GO:0043113 18 9 0,000 0,039632 0,09266725 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,039632 0,09257728 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,039632 0,09248748 ! ruffle organization GO:0031529 15 9 0,000 0,039632 0,09239786 ! retinol metabolic process GO:0042572 18 9 0,000 0,039632 0,09230842 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,039632 0,09221915 ! behavioral fear response GO:0001662 22 9 0,000 0,039632 0,09213004 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,039632 0,09204112 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,039632 0,09195236 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,039632 0,09186377 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,039632 0,09177536 ! protein heterooligomerization GO:0051291 16 9 0,000 0,039632 0,09168711 ! oligodendrocyte development GO:0014003 10 9 0,000 0,039632 0,09159904 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,039632 0,09151113 ! segment specification GO:0007379 13 9 0,000 0,039632 0,09142339 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,039632 0,09133582 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,039632 0,09124842 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,039632 0,09116118 ! response to amine stimulus GO:0014075 13 9 0,000 0,039632 0,09107411 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,039632 0,09098721 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,039632 0,09090047 ! erythrocyte development GO:0048821 15 9 0,000 0,039632 0,0908139 ! gas homeostasis GO:0033483 16 9 0,000 0,039632 0,09072749 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,039632 0,09064125 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,039632 0,09055517 ! renal water homeostasis GO:0003091 14 9 0,000 0,039632 0,09046926 ! postreplication repair GO:0006301 22 9 0,000 0,039632 0,0903835 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,039632 0,09029791 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,039632 0,09021248 ! icosanoid secretion GO:0032309 15 9 0,000 0,039632 0,09012722 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,039632 0,09004211 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,039632 0,08995717 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,039632 0,08987238 ! regulation of cell division GO:0051302 15 9 0,000 0,039632 0,08978776 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,039632 0,08970329 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,039632 0,08961898 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,039632 0,08953483 ! sterol catabolic process GO:0016127 11 9 0,000 0,039632 0,08945084 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,039632 0,08936701 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,039632 0,08928333 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,039632 0,08919981 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,039632 0,08911644 ! musculoskeletal movement GO:0050881 14 9 0,000 0,039632 0,08903324 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,039632 0,08895018 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,039632 0,08886728 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,039632 0,08878454 ! purine base metabolic process GO:0006144 21 9 0,000 0,039632 0,08870195 ! pigment granule transport GO:0051904 17 9 0,000 0,039632 0,08861951 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,039632 0,08853723 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,039632 0,0884551 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,039632 0,08837312 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,039632 0,08829129 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,039632 0,08820962 ! mitochondrion localization GO:0051646 15 9 0,000 0,039632 0,08812809 ! amine catabolic process GO:0009310 117 71 1,000 0,04053684 0,0900569 ! appendage development GO:0048736 136 71 1,000 0,04053684 0,08997383 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,04053684 0,0898909 ! regulation of caspase activity GO:0043281 122 72 1,000 0,04157526 0,09210872 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,04157526 0,09202399 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,04157526 0,09193941 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,04157526 0,09185498 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,04157526 0,09177071 ! respiratory system development GO:0060541 153 72 1,000 0,04157526 0,09168659 ! learning or memory GO:0007611 147 73 1,000 0,04262365 0,09391254 ! regulation of blood pressure GO:0008217 125 73 1,000 0,04262365 0,09382662 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,04368189 0,09606821 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,04368189 0,09598048 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,04368189 0,09589291 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,04368189 0,09580549 ! organelle localization GO:0051640 136 74 1,000 0,04368189 0,09571824 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04393816 0,09619218 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04393816 0,09610473 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04393816 0,09601744 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04393816 0,09593031 ! synapsis GO:0007129 13 10 0,000 0,04393816 0,09584334 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04393816 0,09575652 ! N-glycan processing GO:0006491 20 10 0,000 0,04393816 0,09566987 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04393816 0,09558337 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04393816 0,09549702 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04393816 0,09541083 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04393816 0,0953248 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04393816 0,09523892 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04393816 0,0951532 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04393816 0,09506763 ! androgen metabolic process GO:0008209 17 10 0,000 0,04393816 0,09498221 ! phospholipid efflux GO:0033700 16 10 0,000 0,04393816 0,09489695 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04393816 0,09481184 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04393816 0,09472688 ! lung alveolus development GO:0048286 26 10 0,000 0,04393816 0,09464208 ! pathogenesis GO:0009405 13 10 0,000 0,04393816 0,09455743 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04393816 0,09447292 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04393816 0,09438857 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04393816 0,09430437 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04393816 0,09422032 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04393816 0,09413642 ! endoderm development GO:0007492 16 10 0,000 0,04393816 0,09405267 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04393816 0,09396907 ! arginine catabolic process GO:0006527 13 10 0,000 0,04393816 0,09388561 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04393816 0,09380231 ! proline metabolic process GO:0006560 13 10 0,000 0,04393816 0,09371915 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04393816 0,09363614 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04393816 0,09355328 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04393816 0,09347056 ! V(D)J recombination GO:0033151 28 10 0,000 0,04393816 0,09338799 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04393816 0,09330556 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04393816 0,09322328 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04393816 0,09314115 ! B cell proliferation GO:0042100 18 10 0,000 0,04393816 0,09305916 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04393816 0,09297731 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04393816 0,09289561 ! multicellular organism growth GO:0035264 18 10 0,000 0,04393816 0,09281405 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04393816 0,09273263 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04393816 0,09265136 ! epithelial cell development GO:0002064 20 10 0,000 0,04393816 0,09257023 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04393816 0,09248924 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04393816 0,09240839 ! macroautophagy GO:0016236 17 10 0,000 0,04393816 0,09232769 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04393816 0,09224712 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04393816 0,0921667 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04393816 0,09208641 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04393816 0,09200627 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04393816 0,09192626 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04393816 0,0918464 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04393816 0,09176667 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04393816 0,09168708 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04393816 0,09160763 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04393816 0,09152831 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04393816 0,09144914 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04393816 0,0913701 ! response to dsRNA GO:0043331 20 10 0,000 0,04393816 0,09129119 ! DNA ligation GO:0006266 19 10 0,000 0,04393816 0,09121243 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04393816 0,09113379 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04393816 0,0910553 ! melanosome localization GO:0032400 16 10 0,000 0,04393816 0,09097694 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04393816 0,09089871 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04393816 0,09082062 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04393816 0,09074266 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04393816 0,09066484 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04393816 0,09058715 ! mRNA cleavage GO:0006379 17 10 0,000 0,04393816 0,09050959 ! protein sumoylation GO:0016925 15 10 0,000 0,04393816 0,09043217 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04393816 0,09035487 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04393816 0,09027771 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04393816 0,09020068 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04393816 0,09012379 ! salivary gland development GO:0007431 27 10 0,000 0,04393816 0,09004702 ! prophase GO:0051324 15 10 0,000 0,04393816 0,08997038 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04393816 0,08989388 ! apical protein localization GO:0045176 15 10 0,000 0,04393816 0,0898175 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04393816 0,08974126 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04393816 0,08966514 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04393816 0,08958915 ! midbrain development GO:0030901 13 10 0,000 0,04393816 0,0895133 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04393816 0,08943757 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04393816 0,08936196 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04393816 0,08928649 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04393816 0,08921114 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04393816 0,08913592 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04393816 0,08906083 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04393816 0,08898586 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04393816 0,08891102 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04393816 0,0888363 ! oocyte development GO:0048599 17 10 0,000 0,04393816 0,08876171 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04393816 0,08868725 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04393816 0,08861291 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04393816 0,0885387 ! activation of innate immune response GO:0002218 12 10 0,000 0,04393816 0,0884646 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04393816 0,08839064 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04393816 0,08831679 ! response to nicotine GO:0035094 20 10 0,000 0,04393816 0,08824307 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04393816 0,08816948 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04393816 0,088096 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04393816 0,08802265 ! localization within membrane GO:0051668 20 10 0,000 0,04393816 0,08794942 ! meiotic cell cycle GO:0051321 122 75 1,000 0,04474988 0,08949976 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04474988 0,08942542 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,04582751 0,0915029 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,04691468 0,09359594 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,04691468 0,0935184 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,04691468 0,09344098 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04822514 0,09597163 ! respiratory burst GO:0045730 17 11 0,000 0,04822514 0,09589231 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04822514 0,09581313 ! neuron fate specification GO:0048665 17 11 0,000 0,04822514 0,09573407 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04822514 0,09565515 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04822514 0,09557636 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04822514 0,09549769 ! thyroid gland development GO:0030878 26 11 0,000 0,04822514 0,09541916 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04822514 0,09534075 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04822514 0,09526248 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04822514 0,09518433 ! response to pain GO:0048265 24 11 0,000 0,04822514 0,09510631 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04822514 0,09502842 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04822514 0,09495065 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04822514 0,09487301 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04822514 0,0947955 ! bone resorption GO:0045453 16 11 0,000 0,04822514 0,09471812 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04822514 0,09464086 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04822514 0,09456373 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04822514 0,09448672 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04822514 0,09440984 ! syncytium formation GO:0006949 18 11 0,000 0,04822514 0,09433309 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04822514 0,09425645 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04822514 0,09417995 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04822514 0,09410356 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04822514 0,09402731 ! lipid digestion GO:0044241 18 11 0,000 0,04822514 0,09395117 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04822514 0,09387516 ! UV protection GO:0009650 19 11 0,000 0,04822514 0,09379927 ! adult heart development GO:0007512 14 11 0,000 0,04822514 0,0937235 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04822514 0,09364786 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04822514 0,09357233 ! temperature homeostasis GO:0001659 17 11 0,000 0,04822514 0,09349693 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04822514 0,09342165 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04822514 0,0933465 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04822514 0,09327146 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04822514 0,09319654 ! regulation of organ growth GO:0046620 13 11 0,000 0,04822514 0,09312175 ! pigment granule localization GO:0051875 20 11 0,000 0,04822514 0,09304707 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04822514 0,09297251 ! vasoconstriction GO:0042310 18 11 0,000 0,04822514 0,09289807 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04822514 0,09282376 ! embryonic axis specification GO:0000578 18 11 0,000 0,04822514 0,09274956 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04822514 0,09267548 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04822514 0,09260151 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04822514 0,09252767 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04822514 0,09245394 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04822514 0,09238033 ! zymogen activation GO:0031638 15 11 0,000 0,04822514 0,09230684 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04822514 0,09223346 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04822514 0,0921602 ! nucleosome positioning GO:0016584 15 11 0,000 0,04822514 0,09208706 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04822514 0,09201403 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04822514 0,09194112 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04822514 0,09186833 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04822514 0,09179565 ! acid secretion GO:0046717 18 11 0,000 0,04822514 0,09172308 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04822514 0,09165063 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04822514 0,09157829 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04822514 0,09150607 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04822514 0,09143396 ! oocyte differentiation GO:0009994 18 11 0,000 0,04822514 0,09136196 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04822514 0,09129008 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04822514 0,09121831 ! cholesterol efflux GO:0033344 19 11 0,000 0,04822514 0,09114666 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04822514 0,09107511 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04822514 0,09100368 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04822514 0,09093236 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04822514 0,09086116 ! embryonic gut development GO:0048566 15 11 0,000 0,04822514 0,09079006 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04822514 0,09071907 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04822514 0,0906482 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04822514 0,09057744 ! defense response to fungus GO:0050832 13 11 0,000 0,04822514 0,09050678 ! developmental induction GO:0031128 19 11 0,000 0,04822514 0,09043624 GO:0045168|cell-cell signaling involved in cell fate specification, ! prepulse inhibition GO:0060134 18 11 0,000 0,04822514 0,09036581 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04822514 0,09029548 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04822514 0,09022527 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04822514 0,09015516 ! nucleus localization GO:0051647 19 11 0,000 0,04822514 0,09008517 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04822514 0,09001528 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,04911718 0,09160926 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,04911718 0,0915383 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,04911718 0,09146745 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,04911718 0,09139671 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,04911718 0,09132608 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,04911718 0,09125556 ! response to metal ion GO:0010038 140 80 1,000 0,05023232 0,09325537 ! protein import into nucleus GO:0006606 158 80 1,000 0,05023232 0,09318347 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,05135657 0,09519561 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,05135657 0,09512233 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,05135657 0,09504916 ! nuclear import GO:0051170 161 81 1,000 0,05135657 0,0949761 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,05248983 0,09699734 ! response to drug GO:0042493 143 82 1,000 0,05248983 0,0969229 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05249305 0,09685451 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05249305 0,09678029 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05249305 0,09670619 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05249305 0,0966322 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05249305 0,09655832 ! virus-host interaction GO:0019048 29 12 0,000 0,05249305 0,09648455 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05249305 0,0964109 ! cartilage condensation GO:0001502 20 12 0,000 0,05249305 0,09633736 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05249305 0,09626393 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05249305 0,09619062 ! protein complex disassembly GO:0043241 27 12 0,000 0,05249305 0,09611741 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05249305 0,09604432 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05249305 0,09597134 ! hippocampus development GO:0021766 26 12 0,000 0,05249305 0,09589847 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,05249305 0,09582571 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05249305 0,09575305 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05249305 0,09568051 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05249305 0,09560808 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05249305 0,09553576 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05249305 0,09546355 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05249305 0,09539145 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05249305 0,09531946 ! drug transport GO:0015893 16 12 0,000 0,05249305 0,09524757 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05249305 0,09517579 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05249305 0,09510413 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05249305 0,09503257 ! focal adhesion formation GO:0048041 35 12 0,000 0,05249305 0,09496111 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05249305 0,09488977 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05249305 0,09481853 ! forebrain cell migration GO:0021885 21 12 0,000 0,05249305 0,0947474 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05249305 0,09467637 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05249305 0,09460545 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05249305 0,09453464 ! entry into host cell GO:0030260 32 12 0,000 0,05249305 0,09446393 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05249305 0,09439333 ! monoamine transport GO:0015844 18 12 0,000 0,05249305 0,09432284 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05249305 0,09425245 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05249305 0,09418216 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05249305 0,09411198 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05249305 0,09404191 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05249305 0,09397193 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05249305 0,09390207 ! protein homotetramerization GO:0051289 21 12 0,000 0,05249305 0,0938323 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05249305 0,09376264 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05249305 0,09369309 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05249305 0,09362363 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05249305 0,09355428 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05249305 0,09348503 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05249305 0,09341589 ! cranial nerve development GO:0021545 20 12 0,000 0,05249305 0,09334684 ! fucose catabolic process GO:0019317 22 12 0,000 0,05249305 0,0932779 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05249305 0,09320906 ! histone methylation GO:0016571 26 12 0,000 0,05249305 0,09314032 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05249305 0,09307169 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05249305 0,09300315 ! gland morphogenesis GO:0022612 29 12 0,000 0,05249305 0,09293472 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05249305 0,09286638 ! T cell homeostasis GO:0043029 25 12 0,000 0,05249305 0,09279815 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05249305 0,09273001 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05249305 0,09266198 ! spleen development GO:0048536 22 12 0,000 0,05249305 0,09259405 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05249305 0,09252621 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05249305 0,09245848 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05249305 0,09239084 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05249305 0,0923233 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05249305 0,09225587 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,05249305 0,09218853 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05249305 0,09212128 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05249305 0,09205414 ! response to cold GO:0009409 17 12 0,000 0,05249305 0,09198709 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05249305 0,09192015 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05249305 0,09185329 ! response to oxygen levels GO:0070482 176 83 1,000 0,05363201 0,09377806 ! regulation of ligase activity GO:0051340 142 84 1,000 0,05478299 0,09572104 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,05478299 0,09565157 ! response to unfolded protein GO:0006986 131 85 1,000 0,05594268 0,09760557 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,05594268 0,09753485 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,05594268 0,09746422 GO:0002696|positive regulation of leukocyte activation, ! cGMP metabolic process GO:0046068 18 13 0,000 0,05674196 0,09878521 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05674196 0,09871378 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05674196 0,09864245 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05674196 0,09857123 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05674196 0,09850011 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05674196 0,0984291 ! lipid localization GO:0010876 28 13 0,000 0,05674196 0,09835818 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05674196 0,09828737 ! organelle fusion GO:0048284 32 13 0,000 0,05674196 0,09821666 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05674196 0,09814605 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05674196 0,09807554 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05674196 0,09800514 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05674196 0,09793483 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05674196 0,09786463 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05674196 0,09779453 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05674196 0,09772452 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05674196 0,09765462 ! methionine metabolic process GO:0006555 27 13 0,000 0,05674196 0,09758482 ! plasma membrane organization GO:0007009 24 13 0,000 0,05674196 0,09751511 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05674196 0,09744551 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05674196 0,097376 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05674196 0,0973066 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05674196 0,09723729 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05674196 0,09716808 ! response to X-ray GO:0010165 25 13 0,000 0,05674196 0,09709897 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05674196 0,09702996 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05674196 0,09696105 ! exocrine system development GO:0035272 32 13 0,000 0,05674196 0,09689223 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05674196 0,09682352 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05674196 0,0967549 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05674196 0,09668637 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05674196 0,09661795 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05674196 0,09654962 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05674196 0,09648138 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05674196 0,09641325 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05674196 0,09634521 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05674196 0,09627726 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05674196 0,09620941 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05674196 0,09614166 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05674196 0,096074 ! ribosome assembly GO:0042255 17 13 0,000 0,05674196 0,09600644 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,05674196 0,09593897 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05674196 0,0958716 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05674196 0,09580432 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05674196 0,09573714 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05674196 0,09567005 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05674196 0,09560305 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05674196 0,09553615 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05674196 0,09546934 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05674196 0,09540263 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05674196 0,095336 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05674196 0,09526947 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05674196 0,09520304 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05674196 0,09513669 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05674196 0,09507044 ! embryonic placenta development GO:0001892 23 13 0,000 0,05674196 0,09500428 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05674196 0,09493822 ! insulin secretion GO:0030073 23 13 0,000 0,05674196 0,09487224 ! actin filament polymerization GO:0030041 24 13 0,000 0,05674196 0,09480636 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05674196 0,09474057 ! acrosome reaction GO:0007340 18 13 0,000 0,05674196 0,09467487 ! response to inorganic substance GO:0010035 153 86 1,000 0,05711098 0,09522454 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,05828779 0,09711941 ! protein localization in nucleus GO:0034504 176 87 1,000 0,05828779 0,0970522 ! regulation of protein transport GO:0051223 154 87 1,000 0,05828779 0,09698508 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,05947301 0,09888878 ! regulation of DNA binding GO:0051101 155 88 1,000 0,05947301 0,09882049 ! gland development GO:0048732 206 88 1,000 0,05947301 0,09875229 ! regulation of neurological system process GO:0031644 148 88 1,000 0,05947301 0,09868418 ! rRNA transcription GO:0009303 25 14 0,000 0,06097196 0,10110167 ! lactation GO:0007595 26 14 0,000 0,06097196 0,10103205 ! reproductive cellular process GO:0048610 20 14 0,000 0,06097196 0,10096251 ! tRNA modification GO:0006400 20 14 0,000 0,06097196 0,10089307 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06097196 0,10082373 ! regulation of S phase GO:0033261 23 14 0,000 0,06097196 0,10075449 ! water transport GO:0006833 21 14 0,000 0,06097196 0,10068533 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06097196 0,10061628 ! non-recombinational repair GO:0000726 25 14 0,000 0,06097196 0,10054731 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06097196 0,10047845 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06097196 0,10040967 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06097196 0,10034099 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06097196 0,10027241 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06097196 0,10020391 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06097196 0,10013552 ! palate development GO:0060021 31 14 0,000 0,06097196 0,10006721 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06097196 0,099999 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06097196 0,09993088 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06097196 0,09986285 ! arginine metabolic process GO:0006525 17 14 0,000 0,06097196 0,09979492 ! regulation of heart rate GO:0002027 24 14 0,000 0,06097196 0,09972708 ! organic alcohol transport GO:0015850 29 14 0,000 0,06097196 0,09965933 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06097196 0,09959167 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06097196 0,0995241 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06097196 0,09945663 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06097196 0,09938925 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06097196 0,09932196 ! L-amino acid transport GO:0015807 30 14 0,000 0,06097196 0,09925476 ! bone mineralization GO:0030282 17 14 0,000 0,06097196 0,09918765 ! stem cell development GO:0048864 43 14 0,000 0,06097196 0,09912063 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06097196 0,0990537 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06097196 0,09898686 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06097196 0,09892011 ! cerebellum development GO:0021549 21 14 0,000 0,06097196 0,09885346 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06097196 0,09878689 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06097196 0,09872041 ! response to gamma radiation GO:0010332 28 14 0,000 0,06097196 0,09865402 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06097196 0,09858772 ! cofactor transport GO:0051181 26 14 0,000 0,06097196 0,09852151 ! NADP metabolic process GO:0006739 24 14 0,000 0,06097196 0,09845539 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06097196 0,09838936 ! intestinal absorption GO:0050892 25 14 0,000 0,06097196 0,09832341 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06097196 0,09825756 ! oxygen transport GO:0015671 21 14 0,000 0,06097196 0,09819179 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06097196 0,09812611 ! male genitalia development GO:0030539 24 14 0,000 0,06097196 0,09806051 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06097196 0,09799501 ! regulation of axon extension GO:0030516 37 14 0,000 0,06097196 0,09792959 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,06097196 0,09786426 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06097196 0,09779902 ! sterol metabolic process GO:0016125 152 91 1,000 0,06307817 0,10110998 ! response to protein stimulus GO:0051789 149 91 1,000 0,06307817 0,10104266 ! vitamin metabolic process GO:0006766 139 92 1,000 0,06429607 0,10292504 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06518313 0,10427566 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06518313 0,10420638 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06518313 0,10413718 ! superoxide anion generation GO:0042554 20 15 0,000 0,06518313 0,10406808 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06518313 0,10399907 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06518313 0,10393015 ! copper ion transport GO:0006825 20 15 0,000 0,06518313 0,10386132 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06518313 0,10379259 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06518313 0,10372394 ! sulfate transport GO:0008272 23 15 0,000 0,06518313 0,10365539 ! response to cAMP GO:0051591 22 15 0,000 0,06518313 0,10358692 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06518313 0,10351855 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06518313 0,10345026 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06518313 0,10338207 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06518313 0,10331397 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06518313 0,10324595 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06518313 0,10317803 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06518313 0,10311019 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06518313 0,10304244 ! pituitary gland development GO:0021983 29 15 0,000 0,06518313 0,10297479 ! vesicle coating GO:0006901 33 15 0,000 0,06518313 0,10290722 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06518313 0,10283974 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06518313 0,10277235 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06518313 0,10270504 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,06518313 0,10263783 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06518313 0,1025707 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06518313 0,10250366 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06518313 0,10243671 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06518313 0,10236984 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06518313 0,10230307 ! histone deacetylation GO:0016575 20 15 0,000 0,06518313 0,10223638 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06518313 0,10216977 ! tissue regeneration GO:0042246 26 15 0,000 0,06518313 0,10210326 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06518313 0,10203683 ! water homeostasis GO:0030104 27 15 0,000 0,06518313 0,10197048 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06518313 0,10190422 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06518313 0,10183805 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06518313 0,10177197 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06518313 0,10170597 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06518313 0,10164005 ! cell killing GO:0001906 29 15 0,000 0,06518313 0,10157422 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06518313 0,10150848 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06518313 0,10144282 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06518313 0,10137725 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06518313 0,10131176 ! peptide hormone processing GO:0016486 23 15 0,000 0,06518313 0,10124635 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,06675555 0,10362184 ! forebrain development GO:0030900 188 95 1,000 0,06799695 0,10548077 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06937555 0,10754998 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06937555 0,10748073 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06937555 0,10741156 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06937555 0,10734249 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06937555 0,1072735 ! bone remodeling GO:0046849 27 16 0,000 0,06937555 0,1072046 ! filopodium assembly GO:0046847 32 16 0,000 0,06937555 0,10713579 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06937555 0,10706707 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06937555 0,10699844 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06937555 0,1069299 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06937555 0,10686144 ! startle response GO:0001964 28 16 0,000 0,06937555 0,10679307 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06937555 0,10672479 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06937555 0,10665659 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06937555 0,10658848 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06937555 0,10652046 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06937555 0,10645253 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06937555 0,10638468 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06937555 0,10631692 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06937555 0,10624925 ! response to osmotic stress GO:0006970 25 16 0,000 0,06937555 0,10618166 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06937555 0,10611416 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06937555 0,10604674 ! fructose metabolic process GO:0006000 25 16 0,000 0,06937555 0,10597941 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06937555 0,10591216 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06937555 0,105845 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06937555 0,10577793 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06937555 0,10571094 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06937555 0,10564403 ! axon cargo transport GO:0008088 43 16 0,000 0,06937555 0,10557721 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06937555 0,10551047 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06937555 0,10544382 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06937555 0,10537725 ! DNA replication initiation GO:0006270 27 16 0,000 0,06937555 0,10531077 ! neuron recognition GO:0008038 35 16 0,000 0,06937555 0,10524437 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06937555 0,10517805 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06937555 0,10511182 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06937555 0,10504567 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06937555 0,1049796 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06937555 0,10491362 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06937555 0,10484772 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06937555 0,1047819 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06937555 0,10471616 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06937555 0,10465051 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06937555 0,10458494 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06937555 0,10451945 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06937555 0,10445405 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06937555 0,10438872 ! defense response to virus GO:0051607 37 16 0,000 0,06937555 0,10432348 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,07050261 0,10595208 ! regulation of protein localization GO:0032880 176 97 1,000 0,07050261 0,10588594 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,07176668 0,10771717 GO:0016054|organic acid catabolic process, ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,07303812 0,10955718 GO:0060538|skeletal muscle organ development, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07354931 0,11025522 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07354931 0,11018657 ! metencephalon development GO:0022037 30 17 0,000 0,07354931 0,110118 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07354931 0,11004952 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07354931 0,10998112 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07354931 0,10991281 ! signal complex assembly GO:0007172 41 17 0,000 0,07354931 0,10984459 ! inositol metabolic process GO:0006020 28 17 0,000 0,07354931 0,10977645 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07354931 0,10970839 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07354931 0,10964041 ! glial cell development GO:0021782 27 17 0,000 0,07354931 0,10957253 ! limbic system development GO:0021761 36 17 0,000 0,07354931 0,10950472 ! adult walking behavior GO:0007628 33 17 0,000 0,07354931 0,109437 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07354931 0,10936936 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07354931 0,10930181 ! myoblast differentiation GO:0045445 45 17 0,000 0,07354931 0,10923434 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07354931 0,10916695 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07354931 0,10909965 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,07354931 0,10903243 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07354931 0,10896529 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07354931 0,10889823 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,07354931 0,10883126 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07354931 0,10876437 ! NAD metabolic process GO:0019674 29 17 0,000 0,07354931 0,10869756 ! membrane budding GO:0006900 37 17 0,000 0,07354931 0,10863083 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07354931 0,10856419 ! regulation of protein binding GO:0043393 33 17 0,000 0,07354931 0,10849763 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07354931 0,10843115 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07354931 0,10836475 ! genitalia development GO:0048806 30 17 0,000 0,07354931 0,10829843 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,07354931 0,10823219 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07354931 0,10816603 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07354931 0,10809996 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07354931 0,10803396 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07354931 0,10796805 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07354931 0,10790221 ! steroid catabolic process GO:0006706 31 17 0,000 0,07354931 0,10783646 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07354931 0,10777079 ! gas transport GO:0015669 25 17 0,000 0,07354931 0,10770519 ! organic cation transport GO:0015695 31 17 0,000 0,07354931 0,10763968 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07354931 0,10757424 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07354931 0,10750889 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07354931 0,10744361 ! microspike assembly GO:0030035 36 17 0,000 0,07354931 0,10737842 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07354931 0,1073133 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07354931 0,10724826 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07770448 0,11323864 ! neuron maturation GO:0042551 42 18 0,000 0,07770448 0,11317009 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07770448 0,11310163 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07770448 0,11303324 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07770448 0,11296495 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07770448 0,11289673 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07770448 0,1128286 ! memory GO:0007613 31 18 0,000 0,07770448 0,11276055 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07770448 0,11269258 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07770448 0,11262469 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07770448 0,11255689 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07770448 0,11248916 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07770448 0,11242152 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07770448 0,11235396 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07770448 0,11228648 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,07770448 0,11221908 ! response to fungus GO:0009620 21 18 0,000 0,07770448 0,11215176 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07770448 0,11208452 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07770448 0,11201737 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07770448 0,11195029 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07770448 0,1118833 ! vitamin transport GO:0051180 27 18 0,000 0,07770448 0,11181638 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07770448 0,11174954 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07770448 0,11168279 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07770448 0,11161611 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07770448 0,11154951 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07770448 0,111483 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07770448 0,11141656 ! nerve development GO:0021675 28 18 0,000 0,07770448 0,1113502 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07770448 0,11128392 ! protein secretion GO:0009306 39 19 0,000 0,08184116 0,11713851 ! positive regulation of translation GO:0045727 30 19 0,000 0,08184116 0,11706887 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08184116 0,11699931 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08184116 0,11692983 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,08184116 0,11686044 ! skin development GO:0043588 36 19 0,000 0,08184116 0,11679112 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08184116 0,11672189 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08184116 0,11665275 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08184116 0,11658368 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08184116 0,1165147 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08184116 0,11644579 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08184116 0,11637697 ! cerebral cortex development GO:0021987 36 19 0,000 0,08184116 0,11630823 ! heme metabolic process GO:0042168 36 19 0,000 0,08184116 0,11623957 ! actin filament bundle formation GO:0051017 42 19 0,000 0,08184116 0,11617099 ! neuromuscular junction development GO:0007528 34 19 0,000 0,08184116 0,1161025 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08184116 0,11603408 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08184116 0,11596575 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08184116 0,11589749 ! peptide cross-linking GO:0018149 37 19 0,000 0,08184116 0,11582932 ! protein export from nucleus GO:0006611 36 19 0,000 0,08184116 0,11576122 ! heart process GO:0003015 30 19 0,000 0,08184116 0,11569321 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08184116 0,11562527 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08184116 0,11555742 ! visual learning GO:0008542 36 19 0,000 0,08184116 0,11548964 ! cellular pigmentation GO:0033059 36 19 0,000 0,08184116 0,11542194 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08184116 0,11535433 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08184116 0,11528679 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08184116 0,11521933 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08184116 0,11515195 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08184116 0,11508465 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08184116 0,11501743 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08184116 0,11495028 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08184116 0,11488322 ! cilium assembly GO:0042384 37 19 0,000 0,08184116 0,11481623 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08184116 0,11474932 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08595942 0,12045333 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08595942 0,12038322 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08595942 0,12031319 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08595942 0,12024324 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08595942 0,12017337 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08595942 0,12010359 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08595942 0,12003388 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08595942 0,11996425 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08595942 0,11989471 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08595942 0,11982525 ! response to alkaloid GO:0043279 38 20 0,000 0,08595942 0,11975586 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08595942 0,11968656 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08595942 0,11961734 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,08595942 0,11954819 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08595942 0,11947913 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08595942 0,11941015 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08595942 0,11934124 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,08595942 0,11927242 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,08595942 0,11920367 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08595942 0,11913501 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08595942 0,11906642 ! body fluid secretion GO:0007589 31 20 0,000 0,08595942 0,11899791 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08595942 0,11892948 ! peptide secretion GO:0002790 35 20 0,000 0,08595942 0,11886113 ! stem cell differentiation GO:0048863 53 20 0,000 0,08595942 0,11879286 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08595942 0,11872467 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08595942 0,11865655 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08595942 0,11858852 ! sensory perception of pain GO:0019233 30 20 0,000 0,08595942 0,11852056 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08595942 0,11845268 ! diencephalon development GO:0021536 34 20 0,000 0,08595942 0,11838487 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08595942 0,11831715 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08595942 0,1182495 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08595942 0,11818193 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08595942 0,11811443 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08595942 0,11804702 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08595942 0,11797968 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08595942 0,11791241 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08595942 0,11784523 ! regulation of glucose import GO:0046324 29 20 0,000 0,08595942 0,11777812 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08595942 0,11771108 ! actin filament-based movement GO:0030048 43 20 0,000 0,08595942 0,11764413 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08595942 0,11757724 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,08595942 0,11751044 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08595942 0,11744371 ! negative regulation of translation GO:0017148 29 20 0,000 0,08595942 0,11737706 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08595942 0,11731048 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,08595942 0,11724398 ! regulation of cell killing GO:0031341 42 21 0,000 0,09005935 0,12276646 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,09005935 0,12269694 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09005935 0,1226275 ! hormone secretion GO:0046879 38 21 0,000 0,09005935 0,12255814 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09005935 0,12248886 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09005935 0,12241966 ! axis specification GO:0009798 38 21 0,000 0,09005935 0,12235053 ! ovarian follicle development GO:0001541 35 21 0,000 0,09005935 0,12228149 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,09005935 0,12221252 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09005935 0,12214363 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09005935 0,12207481 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,09005935 0,12200608 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09005935 0,12193742 ! cell aging GO:0007569 44 21 0,000 0,09005935 0,12186884 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09005935 0,12180033 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09005935 0,12173191 ! cytolysis GO:0019835 24 21 0,000 0,09005935 0,12166356 ! vasodilation GO:0042311 39 21 0,000 0,09005935 0,12159528 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09005935 0,12152709 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,09005935 0,12145897 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09005935 0,12139092 ! oogenesis GO:0048477 36 21 0,000 0,09005935 0,12132295 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,09005935 0,12125506 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,09005935 0,12118725 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,09005935 0,12111951 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,09005935 0,12105184 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,09005935 0,12098425 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09005935 0,12091674 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09005935 0,1208493 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,09005935 0,12078194 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09005935 0,12071465 ! collagen catabolic process GO:0030574 28 21 0,000 0,09005935 0,12064744 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09005935 0,1205803 ! gut development GO:0048565 39 21 0,000 0,09005935 0,12051323 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09414102 0,12590511 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09414102 0,12583517 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09414102 0,1257653 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09414102 0,1256955 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09414102 0,12562579 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09414102 0,12555615 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09414102 0,12548659 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09414102 0,12541711 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09414102 0,1253477 ! regeneration GO:0031099 41 22 0,000 0,09414102 0,12527837 ! keratinization GO:0031424 28 22 0,000 0,09414102 0,12520912 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,09414102 0,12513994 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,09414102 0,12507084 ! sensory perception of taste GO:0050909 28 22 0,000 0,09414102 0,12500182 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,09414102 0,12493287 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,09414102 0,124864 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09414102 0,12479521 ! vacuolar transport GO:0007034 36 22 0,000 0,09414102 0,12472649 ! lysosome organization GO:0007040 41 22 0,000 0,09414102 0,12465784 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09414102 0,12458927 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09414102 0,12452078 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09414102 0,12445236 ! fucose metabolic process GO:0006004 39 22 0,000 0,09414102 0,12438402 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09414102 0,12431575 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,09414102 0,12424756 ! ureteric bud development GO:0001657 43 22 0,000 0,09414102 0,12417944 ! renal system process GO:0003014 41 22 0,000 0,09414102 0,1241114 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09414102 0,12404343 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09414102 0,12397553 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09414102 0,12390771 ! sarcomere organization GO:0045214 30 22 0,000 0,09414102 0,12383997 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09414102 0,12377229 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09414102 0,1237047 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09414102 0,12363717 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09414102 0,12356972 ! protein stabilization GO:0050821 39 22 0,000 0,09414102 0,12350234 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09820452 0,12876298 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09820452 0,12869285 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09820452 0,12862279 ! gluconeogenesis GO:0006094 33 23 0,000 0,09820452 0,12855281 ! viral genome replication GO:0019079 41 23 0,000 0,09820452 0,12848291 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09820452 0,12841308 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09820452 0,12834333 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09820452 0,12827366 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09820452 0,12820405 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09820452 0,12813453 ! visual behavior GO:0007632 42 23 0,000 0,09820452 0,12806508 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,09820452 0,12799571 ! response to ethanol GO:0045471 46 23 0,000 0,09820452 0,12792641 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09820452 0,12785718 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09820452 0,12778803 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09820452 0,12771896 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09820452 0,12764996 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09820452 0,12758103 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09820452 0,12751218 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09820452 0,12744341 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09820452 0,1273747 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09820452 0,12730607 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09820452 0,12723752 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09820452 0,12716904 ! platelet activation GO:0030168 37 23 0,000 0,09820452 0,12710063 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09820452 0,1270323 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09820452 0,12696404 ! hormone transport GO:0009914 40 23 0,000 0,09820452 0,12689585 ! cell-cell recognition GO:0009988 25 23 0,000 0,09820452 0,12682774 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09820452 0,1267597 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09820452 0,12669173 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,09820452 0,12662383 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09820452 0,12655601 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09820452 0,12648826 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10224992 0,13162831 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10224992 0,13155792 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,10224992 0,13148761 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10224992 0,13141737 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10224992 0,13134721 ! vesicle docking GO:0048278 47 24 0,000 0,10224992 0,13127712 ! spinal cord development GO:0021510 47 24 0,000 0,10224992 0,1312071 ! vacuole organization GO:0007033 43 24 0,000 0,10224992 0,13113716 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10224992 0,1310673 ! digestive system process GO:0022600 39 24 0,000 0,10224992 0,13099751 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10224992 0,13092779 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10224992 0,13085815 ! regulation of behavior GO:0050795 43 24 0,000 0,10224992 0,13078858 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10224992 0,13071908 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10224992 0,13064966 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10224992 0,13058032 ! membrane depolarization GO:0051899 39 24 0,000 0,10224992 0,13051104 ! pallium development GO:0021543 49 24 0,000 0,10224992 0,13044184 ! pentose metabolic process GO:0019321 35 24 0,000 0,10224992 0,13037272 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,10224992 0,13030366 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,10224992 0,13023468 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10224992 0,13016578 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10224992 0,13009694 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10224992 0,13002818 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10224992 0,12995949 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10224992 0,12989087 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10224992 0,12982233 ! regulation of amine transport GO:0051952 40 24 0,000 0,10224992 0,12975386 ! protein tetramerization GO:0051262 52 24 0,000 0,10224992 0,12968546 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10627731 0,13472245 ! myelination GO:0042552 45 25 0,000 0,10627731 0,13465151 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10627731 0,13458064 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10627731 0,13450985 ! phototransduction GO:0007602 33 25 0,000 0,10627731 0,13443913 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10627731 0,13436848 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,10627731 0,13429791 ! sperm motility GO:0030317 31 25 0,000 0,10627731 0,13422741 ! chromosome condensation GO:0030261 45 25 0,000 0,10627731 0,13415699 ! response to starvation GO:0042594 42 25 0,000 0,10627731 0,13408664 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10627731 0,13401636 ! neural crest cell development GO:0014032 54 25 0,000 0,10627731 0,13394616 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10627731 0,13387603 ! negative regulation of cell development GO:0010721 73 25 0,000 0,10627731 0,13380597 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10627731 0,13373599 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10627731 0,13366608 ! interaction with host GO:0051701 62 25 0,000 0,10627731 0,13359625 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10627731 0,13352648 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10627731 0,13345679 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10627731 0,13338718 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10627731 0,13331763 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10627731 0,13324816 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10627731 0,13317876 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10627731 0,13310943 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,10627731 0,13304018 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10627731 0,13297099 ! telomere organization GO:0032200 43 25 0,000 0,10627731 0,13290188 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10627731 0,13283284 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10627731 0,13276387 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11028677 0,13770107 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11028677 0,13762965 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,11028677 0,1375583 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,11028677 0,13748703 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11028677 0,13741583 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11028677 0,1373447 ! molting cycle process GO:0022404 50 26 0,000 0,11028677 0,13727365 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,11028677 0,13720267 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11028677 0,13713177 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,11028677 0,13706093 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11028677 0,13699017 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11028677 0,13691949 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,11028677 0,13684888 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,11028677 0,13677833 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,11028677 0,13670787 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,11028677 0,13663747 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,11028677 0,13656715 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,11028677 0,1364969 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11028677 0,13642672 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11028677 0,13635661 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11028677 0,13628658 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11028677 0,13621662 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,11028677 0,13614673 ! neuron fate commitment GO:0048663 48 27 0,000 0,11427837 0,14100193 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,11427837 0,14092966 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,11427837 0,14085746 ! iron ion transport GO:0006826 59 27 0,000 0,11427837 0,14078534 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,11427837 0,14071329 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,11427837 0,14064131 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,11427837 0,14056941 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,11427837 0,14049758 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,11427837 0,14042582 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,11427837 0,14035414 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,11427837 0,14028253 ! autophagy GO:0006914 41 27 0,000 0,11427837 0,140211 ! primary neural tube formation GO:0014020 51 27 0,000 0,11427837 0,14013953 ! base-excision repair GO:0006284 41 27 0,000 0,11427837 0,14006814 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,11427837 0,13999682 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,11427837 0,13992558 ! glutathione metabolic process GO:0006749 39 27 0,000 0,11427837 0,13985441 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,11427837 0,13978331 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,11427837 0,13971228 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,11427837 0,13964132 ! circadian rhythm GO:0007623 50 28 0,000 0,1182522 0,14442375 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,1182522 0,14435048 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,1182522 0,14427728 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,1182522 0,14420415 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,1182522 0,1441311 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,1182522 0,14405812 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,1182522 0,14398522 ! synaptogenesis GO:0007416 42 28 0,000 0,1182522 0,14391239 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,1182522 0,14383963 ! lipid oxidation GO:0034440 43 28 0,000 0,1182522 0,14376695 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,1182522 0,14369434 ! translational initiation GO:0006413 65 29 0,000 0,12220833 0,14842667 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12220833 0,14835178 ! regulation of pH GO:0006885 43 29 0,000 0,12220833 0,14827697 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,12220833 0,14820223 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12220833 0,14812757 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12220833 0,14805299 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12220833 0,14797848 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,12220833 0,14790404 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12220833 0,14782968 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12220833 0,14775539 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,12220833 0,14768118 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12220833 0,14760704 ! detection of light stimulus GO:0009583 38 29 0,000 0,12220833 0,14753298 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,12220833 0,14745899 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,12220833 0,14738508 ! tissue homeostasis GO:0001894 48 29 0,000 0,12220833 0,14731124 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,12220833 0,14723747 ! zinc ion transport GO:0006829 45 30 0,000 0,12614684 0,15190655 ! membrane docking GO:0022406 61 30 0,000 0,12614684 0,15183056 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12614684 0,15175464 ! cell junction assembly GO:0034329 78 30 0,000 0,12614684 0,1516788 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12614684 0,15160304 ! acute-phase response GO:0006953 49 30 0,000 0,12614684 0,15152735 ! myofibril assembly GO:0030239 47 30 0,000 0,12614684 0,15145174 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,12614684 0,1513762 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12614684 0,15130074 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,12614684 0,15122535 ! phospholipid transport GO:0015914 51 30 0,000 0,12614684 0,15115004 ! ensheathment of neurons GO:0007272 57 30 0,000 0,12614684 0,15107481 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12614684 0,15099965 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12614684 0,15092456 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,12614684 0,15084955 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12614684 0,15077461 ! eye morphogenesis GO:0048592 60 30 0,000 0,12614684 0,15069975 ! response to heat GO:0009408 50 30 0,000 0,12614684 0,15062496 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1300678 0,15522973 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,1300678 0,15515277 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1300678 0,15507589 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1300678 0,15499908 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,1300678 0,15492235 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1300678 0,15484569 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,1300678 0,15476911 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1300678 0,1546926 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1300678 0,15461617 ! ovulation cycle process GO:0022602 49 31 0,000 0,1300678 0,15453982 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,1300678 0,15446354 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1300678 0,15438734 ! peptide transport GO:0015833 55 31 0,000 0,1300678 0,15431121 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,1300678 0,15423516 ! iron ion homeostasis GO:0055072 54 31 0,000 0,1300678 0,15415918 ! mesoderm formation GO:0001707 69 31 0,000 0,1300678 0,15408328 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,1300678 0,15400745 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1300678 0,1539317 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,1300678 0,15385602 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1300678 0,15378041 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,13397131 0,15831776 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13397131 0,15824004 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13397131 0,1581624 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,13397131 0,15808483 ! cholesterol transport GO:0030301 56 32 0,000 0,13397131 0,15800734 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13397131 0,15792992 ! spliceosome assembly GO:0000245 67 32 0,000 0,13397131 0,15785258 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13397131 0,15777532 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13397131 0,15769813 ! response to ionizing radiation GO:0010212 65 32 0,000 0,13397131 0,15762101 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,13397131 0,15754397 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,13397131 0,15746701 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,13397131 0,15739012 ! muscle cell development GO:0055001 49 32 0,000 0,13397131 0,15731331 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,13397131 0,15723657 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13397131 0,15715991 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,13397131 0,15708332 ! ovulation cycle GO:0042698 51 32 0,000 0,13397131 0,1570068 ! peripheral nervous system development GO:0007422 64 32 0,000 0,13397131 0,15693036 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13397131 0,156854 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,13397131 0,15677771 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13397131 0,15670149 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,13397131 0,15662535 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,13785743 0,16109032 ! post-embryonic development GO:0009791 69 33 0,000 0,13785743 0,16101212 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13785743 0,160934 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13785743 0,16085595 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13785743 0,16077798 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13785743 0,16070008 ! cell fate specification GO:0001708 52 33 0,000 0,13785743 0,16062226 ! sterol transport GO:0015918 57 33 0,000 0,13785743 0,16054452 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13785743 0,16046685 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13785743 0,16038925 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13785743 0,16031173 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,13785743 0,16023429 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13785743 0,16015691 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,14172624 0,16457207 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,14172624 0,16449268 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,14172624 0,16441337 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,14172624 0,16433413 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,14172624 0,16425497 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,14172624 0,16417589 ! mismatch repair GO:0006298 46 34 0,000 0,14172624 0,16409688 ! spermatid development GO:0007286 63 34 0,000 0,14172624 0,16401795 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,14172624 0,1639391 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,14172624 0,16386032 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,14172624 0,16378162 ! regulation of muscle development GO:0048634 70 35 0,000 0,14557781 0,16815181 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,14557781 0,16807112 ! negative regulation of secretion GO:0051048 63 35 0,000 0,14557781 0,16799051 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,14557781 0,16790998 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,14557781 0,16782952 ! odontogenesis GO:0042476 66 35 0,000 0,14557781 0,16774915 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14557781 0,16766884 ! female gonad development GO:0008585 58 35 0,000 0,14557781 0,16758862 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,14557781 0,16750847 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,14557781 0,1674284 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,14557781 0,16734841 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,14557781 0,16726849 ! cytokine production GO:0001816 59 35 0,000 0,14557781 0,16718865 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,14557781 0,16710888 ! neural tube formation GO:0001841 67 35 0,000 0,14557781 0,16702919 ! vesicle localization GO:0051648 64 35 0,000 0,14557781 0,16694958 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,14941223 0,17126528 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,14941223 0,17118373 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14941223 0,17110225 ! cell junction organization GO:0034330 86 36 0,000 0,14941223 0,17102085 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,14941223 0,17093953 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,14941223 0,17085828 ! positive regulation of cell development GO:0010720 80 36 0,000 0,14941223 0,17077712 ! regulation of proteolysis GO:0030162 72 36 0,000 0,14941223 0,17069603 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14941223 0,17061501 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14941223 0,17053407 ! aerobic respiration GO:0009060 55 36 0,000 0,14941223 0,17045321 ! embryonic organ development GO:0048568 57 36 0,000 0,14941223 0,17037243 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,14941223 0,17029172 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,14941223 0,17021109 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15322957 0,17447721 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,15322957 0,17439468 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,15322957 0,17431222 ! actomyosin structure organization GO:0031032 62 37 0,000 0,15322957 0,17422984 ! organic anion transport GO:0015711 68 37 0,000 0,15322957 0,17414754 ! tissue remodeling GO:0048771 76 37 0,000 0,15322957 0,17406532 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,15322957 0,17398317 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,15322957 0,17390111 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15322957 0,17381912 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,15322957 0,1737372 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15322957 0,17365537 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,15322957 0,17357361 ! pigment metabolic process GO:0042440 80 37 0,000 0,15322957 0,17349193 ! spermatid differentiation GO:0048515 66 37 0,000 0,15322957 0,17341032 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,1570299 0,17762762 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,1570299 0,17754415 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,1570299 0,17746075 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,1570299 0,17737744 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,1570299 0,1772942 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,1570299 0,17721104 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,1570299 0,17712796 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,1570299 0,17704496 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,1570299 0,17696204 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,1570299 0,17687919 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,1570299 0,17679642 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,1570299 0,17671373 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1608133 0,18088677 ! mammary gland development GO:0030879 86 39 0,000 0,1608133 0,18080225 ! learning GO:0007612 77 39 0,000 0,1608133 0,1807178 ! ear morphogenesis GO:0042471 60 39 0,000 0,1608133 0,18063343 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1608133 0,18054914 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1608133 0,18046493 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1608133 0,1803808 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,1608133 0,18029674 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1608133 0,18021277 ! RNA modification GO:0009451 57 39 0,000 0,1608133 0,18012887 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1608133 0,18004505 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,16457985 0,18417634 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,16457985 0,18409071 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,16457985 0,18400517 ! feeding behavior GO:0007631 59 40 0,000 0,16457985 0,1839197 ! negative regulation of binding GO:0051100 72 40 0,000 0,16457985 0,18383432 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,16457985 0,18374901 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,16457985 0,18366379 ! maintenance of protein location GO:0045185 91 40 0,000 0,16457985 0,18357864 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,16832962 0,18767426 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,16832962 0,18758734 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,16832962 0,18750049 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,16832962 0,18741373 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,16832962 0,18732704 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,16832962 0,18724044 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,16832962 0,18715391 ! female gamete generation GO:0007292 61 41 0,000 0,16832962 0,18706746 ! polyol metabolic process GO:0019751 66 41 0,000 0,16832962 0,1869811 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,16832962 0,18689481 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,17206268 0,19095148 ! regulation of tube size GO:0035150 71 42 0,000 0,17206268 0,19086344 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,17206268 0,19077549 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,17206268 0,19068761 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,17206268 0,19059982 ! neuron migration GO:0001764 79 42 0,000 0,17206268 0,1905121 ! regulation of protein secretion GO:0050708 71 42 0,000 0,17206268 0,19042447 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,1757791 0,19444806 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,1757791 0,1943587 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,1757791 0,19426942 ! glucose transport GO:0015758 65 43 0,000 0,1757791 0,19418022 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,1757791 0,19409111 ! neural tube development GO:0021915 77 43 0,000 0,1757791 0,19400208 ! striated muscle contraction GO:0006941 77 43 0,000 0,1757791 0,19391313 ! phagocytosis GO:0006909 90 43 0,000 0,1757791 0,19382426 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,1757791 0,19373547 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17947897 0,19772271 ! hexose transport GO:0008645 67 44 0,000 0,17947897 0,19763222 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,17947897 0,19754181 ! double-strand break repair GO:0006302 81 44 0,000 0,17947897 0,19745149 ! B cell differentiation GO:0030183 107 44 0,000 0,17947897 0,19736125 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,17947897 0,19727109 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,17947897 0,19718101 ! maintenance of location in cell GO:0051651 97 44 0,000 0,17947897 0,19709101 ! glycolysis GO:0006096 65 45 0,000 0,18316235 0,20104408 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,18316235 0,2009524 ! leukocyte migration GO:0050900 68 45 0,000 0,18316235 0,20086081 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,18316235 0,2007693 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,18316235 0,20067788 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,18316235 0,20058654 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,18316235 0,20049528 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,18316235 0,2004041 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18316235 0,20031301 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,18316235 0,200222 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,18682932 0,20413776 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,18682932 0,2040451 ! positive regulation of defense response GO:0031349 76 47 0,000 0,19047995 0,20793773 ! endosome transport GO:0016197 108 47 0,000 0,19047995 0,20784343 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,19047995 0,20774921 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,19047995 0,20765508 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,19047995 0,20756103 ! protein homooligomerization GO:0051260 76 47 0,000 0,19047995 0,20746707 ! mitochondrial transport GO:0006839 82 48 0,000 0,19411431 0,21132988 ! Notch signaling pathway GO:0007219 96 48 0,000 0,19411431 0,2112343 ! cellular component disassembly GO:0022411 86 48 0,000 0,19411431 0,2111388 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,19411431 0,21104339 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,19411431 0,21094807 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,19411431 0,21085284 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,19411431 0,21075769 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,19411431 0,21066262 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,19773247 0,21449249 ! regulation of action potential GO:0001508 95 49 0,000 0,19773247 0,21439582 ! regulation of ion transport GO:0043269 77 49 0,000 0,19773247 0,21429925 ! peptide metabolic process GO:0006518 76 49 0,000 0,19773247 0,21420276 ! response to temperature stimulus GO:0009266 76 49 0,000 0,19773247 0,21410636 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,19773247 0,21401005 ! endocrine system development GO:0035270 104 49 0,000 0,19773247 0,21391382 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,19773247 0,21381768 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,19773247 0,21372162 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,19773247 0,21362566 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,19773247 0,21352977 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,20133451 0,21732205 ! neuromuscular process GO:0050905 99 50 0,000 0,20133451 0,21722459 ! inner ear development GO:0048839 79 50 0,000 0,20133451 0,21712723 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,20133451 0,21702995 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,20133451 0,21693275 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,2049205 0,22069773 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,2049205 0,22059898 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,2049205 0,22050032 ! excretion GO:0007588 83 51 0,000 0,2049205 0,22040175 ! chromatin remodeling GO:0006338 109 51 0,000 0,2049205 0,22030327 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,2049205 0,22020488 ! vesicle organization GO:0016050 107 51 0,000 0,2049205 0,22010657 ! regulation of cell shape GO:0008360 125 51 0,000 0,2049205 0,22000835 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,2049205 0,21991022 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,2084905 0,22364162 ! membrane fusion GO:0006944 110 52 0,000 0,2084905 0,22354196 ! positive regulation of growth GO:0045927 90 52 0,000 0,2084905 0,22344238 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,2084905 0,2233429 ! amino acid activation GO:0043038 92 52 0,000 0,2084905 0,2232435 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,2084905 0,2231442 ! synapse organization GO:0050808 85 52 0,000 0,2084905 0,22304498 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,2120446 0,22674635 ! RNA catabolic process GO:0006401 93 53 0,000 0,2120446 0,22664562 ! regulation of translational initiation GO:0006446 82 53 0,000 0,2120446 0,22654498 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,2120446 0,22644443 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,2120446 0,22634397 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,2120446 0,22624359 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,21558285 0,22991681 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,21558285 0,22981494 ! cell recognition GO:0008037 85 54 0,000 0,21558285 0,22971317 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,21558285 0,22961148 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,21558285 0,22950988 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,21558285 0,22940837 ! chloride transport GO:0006821 90 55 0,000 0,21910533 0,23305368 ! glucose catabolic process GO:0006007 82 55 0,000 0,21910533 0,23295069 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,21910533 0,2328478 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,21910533 0,232745 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,21910533 0,23264228 ! gastrulation GO:0007369 112 55 0,000 0,21910533 0,23253966 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,21910533 0,23243713 ! nuclear export GO:0051168 97 55 0,000 0,21910533 0,23233469 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,21910533 0,23223234 ! sensory perception of smell GO:0007608 80 56 0,000 0,22261211 0,23584532 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,22261211 0,23574152 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,22261211 0,2356378 ! proton transport GO:0015992 94 56 0,000 0,22261211 0,23553418 ! muscle fiber development GO:0048747 112 57 0,000 0,22610325 0,23912282 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,22610325 0,23901776 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,22610325 0,23891279 ! maintenance of location GO:0051235 118 57 0,000 0,22610325 0,23880791 ! hydrogen transport GO:0006818 97 58 0,000 0,22957884 0,24237239 ! regulation of endocytosis GO:0030100 91 58 0,000 0,22957884 0,24226609 ! adult behavior GO:0030534 99 58 0,000 0,22957884 0,24215988 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,22957884 0,24205376 ! positive regulation of secretion GO:0051047 95 59 0,000 0,23303893 0,24559424 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,23303893 0,24548672 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,23303893 0,24537928 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,23303893 0,24527194 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,23648359 0,2487886 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,23648359 0,24867986 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,23648359 0,24857122 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,23648359 0,24846267 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,23648359 0,24835422 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2399129 0,25184574 ! mesoderm development GO:0007498 119 61 0,000 0,2399129 0,25173591 ! tRNA processing GO:0008033 89 61 0,000 0,2399129 0,25162617 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2399129 0,25151653 ! ear development GO:0043583 103 62 0,000 0,24332692 0,25498457 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,24332692 0,25487356 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,24672572 0,25832118 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,25010936 0,26174994 ! cell redox homeostasis GO:0045454 102 64 0,000 0,25010936 0,26163614 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,25010936 0,26152243 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,25010936 0,26140883 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,25010936 0,26129532 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,25010936 0,26118191 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,25347792 0,26458476 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,25347792 0,26447002 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,25683145 0,26785283 ! actin filament organization GO:0007015 148 66 0,000 0,25683145 0,26773678 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,25683145 0,26762082 ! extracellular matrix organization GO:0030198 133 66 0,000 0,25683145 0,26750497 ! secondary metabolic process GO:0019748 116 66 0,000 0,25683145 0,26738922 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,26017004 0,27074788 ! activation of MAPK activity GO:0000187 115 67 0,000 0,26017004 0,27063083 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,26017004 0,27051388 ! hexose catabolic process GO:0019320 104 67 0,000 0,26017004 0,27039702 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,26017004 0,27028027 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,26017004 0,27016362 ! adaptive immune response GO:0002250 119 67 0,000 0,26017004 0,27004707 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,26017004 0,26993062 ! amino acid transport GO:0006865 125 68 0,000 0,26349373 0,27326117 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,26349373 0,27314344 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,26349373 0,27302581 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,26349373 0,27290827 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,26349373 0,27279084 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,26349373 0,27267351 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,26680261 0,27597896 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,26680261 0,27586037 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,26680261 0,27574187 ! humoral immune response GO:0006959 109 71 0,000 0,27337615 0,28241435 ! B cell activation GO:0042113 160 71 0,000 0,27337615 0,28229314 ! regulation of immune effector process GO:0002697 137 71 0,000 0,27337615 0,28217204 ! acute inflammatory response GO:0002526 113 72 0,000 0,27664095 0,28541944 ! carbohydrate transport GO:0008643 110 72 0,000 0,27664095 0,2852971 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,27989119 0,28852537 ! axon guidance GO:0007411 139 73 0,000 0,27989119 0,2884018 ! fertilization GO:0009566 90 73 0,000 0,27989119 0,28827834 ! transition metal ion transport GO:0000041 126 74 0,000 0,28312694 0,29148627 ! neurotransmitter transport GO:0006836 123 74 0,000 0,28312694 0,29136159 ! exocytosis GO:0006887 133 74 0,000 0,28312694 0,29123703 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,28312694 0,29111257 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,28634825 0,29429897 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,28634825 0,29417331 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,28634825 0,29404775 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,28634825 0,29392231 ! rhythmic process GO:0048511 128 75 0,000 0,28634825 0,29379697 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,28955519 0,29696069 ! defense response to bacterium GO:0042742 89 76 0,000 0,28955519 0,29683417 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,28955519 0,29670775 ! regulation of catabolic process GO:0009894 161 76 0,000 0,28955519 0,29658143 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,29274783 0,29972395 ! blood coagulation GO:0007596 146 78 0,000 0,29592623 0,30284921 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,29592623 0,30272045 ! protein oligomerization GO:0051259 139 78 0,000 0,29592623 0,3025918 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,29909044 0,30569737 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,30224055 0,30878588 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,30224055 0,30865482 ! inorganic anion transport GO:0015698 138 80 0,000 0,30224055 0,30852387 ! digestion GO:0007586 112 81 0,000 0,3053766 0,31159292 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,3053766 0,31146083 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,3053766 0,31132885 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,30849866 0,31437855 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,30849866 0,31424546 ! regulation of lyase activity GO:0051339 160 83 0,000 0,31160679 0,31727716 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,31470105 0,32029218 ! hemostasis GO:0007599 158 84 0,000 0,31470105 0,32015675 ! negative regulation of transport GO:0051051 153 84 0,000 0,31470105 0,32002144 ! nucleosome assembly GO:0006334 122 85 0,000 0,31778151 0,32301745 ! amine biosynthetic process GO:0009309 138 86 0,000 0,32084822 0,32599696 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,32084822 0,32585935 ! chromatin assembly GO:0031497 124 86 0,000 0,32084822 0,32572186 ! tube morphogenesis GO:0035239 176 86 0,000 0,32084822 0,32558448 ! mitochondrion organization GO:0007005 148 86 0,000 0,32084822 0,32544722 ! alcohol catabolic process GO:0046164 130 86 0,000 0,32084822 0,32531008 ! amine transport GO:0015837 155 86 0,000 0,32084822 0,32517305 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,32390125 0,32812901 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,32694065 0,33106869 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,32694065 0,33092941 ! cellular defense response GO:0006968 114 89 0,000 0,32996649 0,33385172 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,32996649 0,33371138 ! ossification GO:0001503 188 90 0,000 0,33297883 0,33661642 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,33297883 0,33647504 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,33297883 0,33633378 ! bone development GO:0060348 189 91 0,000 0,33597773 0,33922048 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,33597773 0,33907819 ! regulation of defense response GO:0031347 149 92 0,000 0,33896324 0,34194782 ! nucleosome organization GO:0034728 138 92 0,000 0,33896324 0,34180451 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,33896324 0,34166131 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,34193543 0,34451283 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,34193543 0,34436862 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,34193543 0,34422454 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,34193543 0,34408057 ! regulation of membrane potential GO:0042391 164 93 0,000 0,34193543 0,34393672 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,34193543 0,343793 ! female pregnancy GO:0007565 164 94 0,000 0,34489435 0,34662315 ! regulation of T cell activation GO:0050863 158 94 0,000 0,34489435 0,34647842 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,34784007 0,34929182 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,35077264 0,35208968 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,35077264 0,35194286 ! positive regulation of immune response GO:0050778 156 96 0,000 0,35077264 0,35179615 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,35369212 0,35457635 ! protein ubiquitination GO:0016567 217 97 0,000 0,35369212 0,35442867 ! hormone metabolic process GO:0042445 157 97 0,000 0,35369212 0,35428112 ! response to virus GO:0009615 160 98 0,000 0,35659857 0,35704376 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,35659857 0,35689524 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,35949204 0,35964152 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,35949204 0,35949204