pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1180-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 224 98 7,000 9,516E-09 2,325E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 5,000 4,163E-08 5,085E-05 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 3,000 9,826E-08 8,002E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 5,000 1,552E-07 9,48E-05 ! epithelial to mesenchymal transition GO:0001837 30 15 3,000 4,011E-07 1,96E-04 ! G1 phase GO:0051318 44 22 3,000 2,101E-06 8,553E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 3,032E-06 1,058E-03 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 4,062E-06 1,24E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 4,237E-06 1,15E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 2,000 6,074E-06 1,484E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 1,302E-05 2,892E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 1,806E-05 3,676E-03 ! gliogenesis GO:0042063 91 41 3,000 2,732E-05 5,135E-03 ! mesenchymal cell development GO:0014031 94 41 3,000 2,732E-05 4,768E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 3,229E-05 5,26E-03 ! epithelial cell differentiation GO:0030855 83 43 3,000 3,308E-05 5,051E-03 ! negative regulation of cell cycle process GO:0010948 35 17 2,000 4,796E-05 6,893E-03 ! detection of bacterium GO:0016045 22 18 2,000 5,738E-05 7,788E-03 ! G1 phase of mitotic cell cycle GO:0000080 39 19 2,000 6,793E-05 8,734E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 7,967E-05 9,731E-03 ! response to UV GO:0009411 120 55 3,000 8,79E-05 0,01022571 ! peptidyl-serine modification GO:0018209 50 22 2,000 1,07E-04 0,01187695 ! detection of biotic stimulus GO:0009595 34 24 2,000 1,397E-04 0,01483886 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 1,583E-04 0,01610982 ! glial cell fate commitment GO:0021781 14 5 1,000 1,754E-04 0,0171443 ! microvillus organization GO:0032528 8 5 1,000 1,754E-04 0,01648491 GO:0030033|microvillus assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 1,754E-04 0,01587436 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 1,754E-04 0,01530742 ! meiotic chromosome segregation GO:0045132 10 5 1,000 1,754E-04 0,01477957 ! muscle cell proliferation GO:0033002 12 5 1,000 1,754E-04 0,01428692 ! receptor biosynthetic process GO:0032800 7 5 1,000 1,754E-04 0,01382605 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,784E-04 0,01361613 ! blastocyst development GO:0001824 50 26 2,000 1,784E-04 0,01320352 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 1,792E-04 0,01287518 ! negative regulation of cell growth GO:0030308 142 67 3,000 1,899E-04 0,01325804 ! regulation of chromosome organization GO:0033044 49 27 2,000 2E-04 0,01357407 ! negative regulation of cell size GO:0045792 144 69 3,000 2,128E-04 0,01405311 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 2,128E-04 0,01368329 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 2,233E-04 0,01399016 ! fat cell differentiation GO:0045444 57 28 2,000 2,233E-04 0,01364041 ! negative regulation of kinase activity GO:0033673 145 70 3,000 2,25E-04 0,01340682 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,483E-04 0,01444507 ! regulation of smooth muscle cell differentiation GO:0051150 12 6 1,000 2,624E-04 0,01490996 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 2,624E-04 0,0145711 ! establishment of spindle localization GO:0051293 16 6 1,000 2,624E-04 0,0142473 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 2,624E-04 0,01393757 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 2,624E-04 0,01364103 ! negative regulation of transferase activity GO:0051348 155 74 3,000 2,787E-04 0,01418436 ! steroid biosynthetic process GO:0006694 146 79 3,000 3,58E-04 0,01785041 ! prostate gland development GO:0030850 14 7 1,000 3,664E-04 0,01790183 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,664E-04 0,01755081 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 3,664E-04 0,01721329 ! lipoprotein transport GO:0042953 14 7 1,000 3,664E-04 0,01688852 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 3,664E-04 0,01657577 ! monocyte differentiation GO:0030224 16 7 1,000 3,664E-04 0,01627439 ! peptidyl-threonine modification GO:0018210 26 7 1,000 3,664E-04 0,01598377 ! negative regulation of organelle organization GO:0010639 181 80 3,000 3,756E-04 0,01610011 ! glial cell differentiation GO:0010001 67 34 2,000 4,005E-04 0,01686759 ! negative regulation of growth GO:0045926 168 85 3,000 4,731E-04 0,01959104 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,872E-04 0,01983579 ! ER overload response GO:0006983 13 8 1,000 4,872E-04 0,01951061 ! cardiac muscle cell differentiation GO:0055007 31 8 1,000 4,872E-04 0,01919593 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 4,872E-04 0,01889123 ! blastocyst growth GO:0001832 19 8 1,000 4,872E-04 0,01859605 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 4,872E-04 0,01830996 ! positive regulation of smooth muscle contraction GO:0045987 15 8 1,000 4,872E-04 0,01803254 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 4,872E-04 0,01776339 GO:0000076|DNA replication checkpoint, ! cellular response to insulin stimulus GO:0032869 85 38 2,000 5,576E-04 0,02003332 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 6,246E-04 0,02211522 ! glycine catabolic process GO:0006546 15 9 1,000 6,246E-04 0,02179929 ! retinoic acid receptor signaling pathway GO:0048384 16 9 1,000 6,246E-04 0,02149225 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 6,246E-04 0,02119375 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 6,246E-04 0,02090342 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 7,786E-04 0,02570479 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 7,786E-04 0,02536206 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 7,786E-04 0,02502835 ! regulation of fat cell differentiation GO:0045598 18 10 1,000 7,786E-04 0,0247033 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 7,786E-04 0,0243866 ! serine family amino acid catabolic process GO:0009071 18 10 1,000 7,786E-04 0,0240779 ! blastocyst formation GO:0001825 18 10 1,000 7,786E-04 0,02377693 ! striated muscle cell differentiation GO:0051146 91 43 2,000 8,033E-04 0,02422652 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 8,033E-04 0,02393108 ! keratinocyte differentiation GO:0030216 81 45 2,000 9,179E-04 0,02701793 ! melanocyte differentiation GO:0030318 20 11 1,000 9,49E-04 0,02760022 GO:0050931|pigment cell differentiation, ! positive regulation of muscle contraction GO:0045933 19 11 1,000 9,49E-04 0,02727551 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 9,49E-04 0,02695835 ! alpha-beta T cell activation GO:0046631 26 11 1,000 9,49E-04 0,02664849 ! DNA methylation GO:0006306 19 11 1,000 9,49E-04 0,02634566 GO:0006305|DNA alkylation, ! cardiac cell differentiation GO:0035051 36 11 1,000 9,49E-04 0,02604965 ! lysogeny GO:0030069 22 11 1,000 9,49E-04 0,0257602 GO:0019047|provirus integration, ! regulation of embryonic development GO:0045995 35 11 1,000 9,49E-04 0,02547713 ! pigmentation GO:0043473 103 46 2,000 9,789E-04 0,0259952 ! response to insulin stimulus GO:0032868 98 47 2,000 1,042E-03 0,0273845 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,109E-03 0,02881048 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,136E-03 0,02920423 ! T cell proliferation GO:0042098 32 12 1,000 1,136E-03 0,02890002 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 1,136E-03 0,02860208 ! histone acetylation GO:0016573 27 12 1,000 1,136E-03 0,02831022 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,136E-03 0,02802426 ! regulation of gene expression, epigenetic GO:0040029 116 50 2,000 1,249E-03 0,03050095 ! epidermal cell differentiation GO:0009913 87 50 2,000 1,249E-03 0,03019896 ! chromatin silencing GO:0006342 29 13 1,000 1,338E-03 0,03205653 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 1,338E-03 0,0317453 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 2,000 1,399E-03 0,03286562 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 1,557E-03 0,03623024 ! covalent chromatin modification GO:0016569 115 54 2,000 1,561E-03 0,03596876 ! RNA elongation GO:0006354 90 56 2,000 1,733E-03 0,03957736 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,792E-03 0,04053051 ! muscle maintenance GO:0046716 26 15 1,000 1,792E-03 0,04015867 ! dopamine metabolic process GO:0042417 35 15 1,000 1,792E-03 0,0397936 ! heart morphogenesis GO:0003007 105 57 2,000 1,824E-03 0,04014699 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 2,042E-03 0,04454281 ! regulation of neurotransmitter secretion GO:0046928 35 16 1,000 2,042E-03 0,04414863 ! endothelial cell migration GO:0043542 31 17 1,000 2,308E-03 0,04945916 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 2,308E-03 0,04902908 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 1,000 2,308E-03 0,04860642 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 2,308E-03 0,04819098 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 2,308E-03 0,04778258 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 2,542E-03 0,05218826 ! heart looping GO:0001947 34 18 1,000 2,589E-03 0,05271346 ! epidermis morphogenesis GO:0048730 43 18 1,000 2,589E-03 0,05227781 ! glycine metabolic process GO:0006544 30 18 1,000 2,589E-03 0,0518493 ! response to retinoic acid GO:0032526 31 18 1,000 2,589E-03 0,05142777 ! DNA integration GO:0015074 32 18 1,000 2,589E-03 0,05101303 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 1,000 2,589E-03 0,05060492 ! long-chain fatty acid transport GO:0015909 32 18 1,000 2,589E-03 0,0502033 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 2,775E-03 0,05337945 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 2,886E-03 0,05508033 ! pigmentation during development GO:0048066 42 19 1,000 2,886E-03 0,05465335 ! response to vitamin A GO:0033189 32 19 1,000 2,886E-03 0,05423294 ! myeloid cell differentiation GO:0030099 126 67 2,000 2,896E-03 0,05400926 ! detection of external stimulus GO:0009581 102 68 2,000 3,02E-03 0,05590212 ! urogenital system development GO:0001655 149 69 2,000 3,148E-03 0,057826 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,198E-03 0,05829867 ! protein amino acid acetylation GO:0006473 41 20 1,000 3,198E-03 0,05786683 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 3,198E-03 0,05744134 ! response to vitamin GO:0033273 36 20 1,000 3,198E-03 0,05702206 ! cellular response to unfolded protein GO:0034620 35 20 1,000 3,198E-03 0,05660885 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 3,198E-03 0,0562016 ! cell cycle checkpoint GO:0000075 145 71 2,000 3,413E-03 0,05956005 ! lipid phosphorylation GO:0046834 43 21 1,000 3,525E-03 0,06106746 ! regulation of neurotransmitter transport GO:0051588 44 21 1,000 3,525E-03 0,06063741 ! hindlimb morphogenesis GO:0035137 47 22 1,000 3,866E-03 0,06605199 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 3,866E-03 0,06559329 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,866E-03 0,06514093 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,866E-03 0,06469475 ! response to cytokine stimulus GO:0034097 69 22 1,000 3,866E-03 0,06425465 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 3,866E-03 0,0638205 ! reproductive structure development GO:0048608 131 75 2,000 3,983E-03 0,06531029 ! eye development GO:0001654 155 75 2,000 3,983E-03 0,06487489 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 4,223E-03 0,06832099 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,223E-03 0,06787151 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 4,223E-03 0,06742791 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 4,223E-03 0,06699007 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 1,000 4,223E-03 0,06655787 GO:0060415|muscle tissue morphogenesis, ! DNA modification GO:0006304 36 23 1,000 4,223E-03 0,06613122 ! fatty acid transport GO:0015908 47 23 1,000 4,223E-03 0,06571 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 4,594E-03 0,07103357 ! barbed-end actin filament capping GO:0051016 58 24 1,000 4,594E-03 0,07058682 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 1,000 4,594E-03 0,07014565 ! muscle cell differentiation GO:0042692 178 81 2,000 4,941E-03 0,07498043 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 2,000 4,941E-03 0,07451759 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 4,98E-03 0,07463573 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 4,98E-03 0,07418063 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 4,98E-03 0,07373105 ! vasculogenesis GO:0001570 49 25 1,000 4,98E-03 0,07328689 ! negative regulation of DNA replication GO:0008156 45 25 1,000 4,98E-03 0,07284804 ! receptor metabolic process GO:0043112 53 25 1,000 4,98E-03 0,07241442 ! lymphocyte proliferation GO:0046651 55 25 1,000 4,98E-03 0,07198594 ! initiation of viral infection GO:0019059 60 26 1,000 5,38E-03 0,07731244 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 5,38E-03 0,07686032 ! positive regulation of nuclear division GO:0051785 41 26 1,000 5,38E-03 0,07641346 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 5,38E-03 0,07597177 ! T cell activation GO:0042110 189 84 2,000 5,468E-03 0,07677275 ! response to nutrient GO:0007584 135 84 2,000 5,468E-03 0,07633405 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 5,651E-03 0,0784369 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 5,794E-03 0,07997441 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 5,794E-03 0,07952512 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 5,794E-03 0,07908085 ! response to toxin GO:0009636 49 27 1,000 5,794E-03 0,07864151 ! leukocyte proliferation GO:0070661 59 27 1,000 5,794E-03 0,07820702 GO:0032943|mononuclear cell proliferation, ! protein amino acid acylation GO:0043543 59 28 1,000 6,223E-03 0,08352958 ! negative regulation of protein modification process GO:0031400 66 28 1,000 6,223E-03 0,08307313 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 6,223E-03 0,08262165 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 6,223E-03 0,08217505 ! regulation of cell cycle process GO:0010564 161 90 2,000 6,619E-03 0,08694036 ! catechol metabolic process GO:0009712 55 29 1,000 6,665E-03 0,08707778 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! somitogenesis GO:0001756 52 29 1,000 6,665E-03 0,0866146 ! regulation of cell adhesion GO:0030155 241 92 2,000 7,033E-03 0,09090253 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 7,122E-03 0,09157187 ! phenol metabolic process GO:0018958 56 30 1,000 7,122E-03 0,09109243 ! negative regulation of protein complex assembly GO:0031333 68 30 1,000 7,122E-03 0,09061799 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 7,122E-03 0,09014847 ! cell fate determination GO:0001709 64 30 1,000 7,122E-03 0,08968379 ! regulation of B cell activation GO:0050864 55 30 1,000 7,122E-03 0,08922387 ! male gonad development GO:0008584 56 31 1,000 7,592E-03 0,09462963 ! erythrocyte differentiation GO:0030218 62 31 1,000 7,592E-03 0,09414928 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 7,592E-03 0,09367378 ! natural killer cell activation GO:0030101 50 31 1,000 7,592E-03 0,09320305 ! sex differentiation GO:0007548 171 96 2,000 7,904E-03 0,09655076 ! spindle organization GO:0007051 50 32 1,000 8,076E-03 0,09815675 ! metanephros development GO:0001656 81 32 1,000 8,076E-03 0,09767082 ! hindbrain development GO:0030902 65 32 1,000 8,076E-03 0,09718969 ! gene silencing GO:0016458 71 32 1,000 8,076E-03 0,09671327 ! transcription initiation GO:0006352 171 97 2,000 8,132E-03 0,09690599 ! leukocyte differentiation GO:0002521 232 98 2,000 8,363E-03 0,0991779 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 8,573E-03 0,10118189 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 9,084E-03 0,10669494 ! serine family amino acid metabolic process GO:0009069 56 34 1,000 9,084E-03 0,10618444 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 9,608E-03 0,11177571 ! placenta development GO:0001890 53 35 1,000 9,608E-03 0,11124597 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01014548 0,11691234 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 0,01014548 0,11636345 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01069579 0,12210189 ! meiosis I GO:0007127 74 38 1,000 0,01125902 0,12793386 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01125902 0,12734157 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01125902 0,12675474 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,01183506 0,13262868 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01183506 0,13202307 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01183506 0,13142296 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 0,01183506 0,13082829 GO:0006073|cellular glucan metabolic process, ! lipid homeostasis GO:0055088 75 40 1,000 0,0124238 0,13671773 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01363889 0,14941621 ! T cell differentiation GO:0030217 93 42 1,000 0,01363889 0,14874918 ! cytokinesis GO:0000910 84 42 1,000 0,01363889 0,14808807 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01426502 0,1542011 GO:0090047|positive regulation of transcription regulator activity, ! monocarboxylic acid transport GO:0015718 93 43 1,000 0,01426502 0,1535218 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,01426502 0,15284846 ! segmentation GO:0035282 78 43 1,000 0,01426502 0,152181 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,01490339 0,15829988 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,01490339 0,1576146 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,01555387 0,16378496 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 0,01555387 0,16308202 ! biopolymer methylation GO:0043414 91 45 1,000 0,01555387 0,16238509 ! developmental growth GO:0048589 88 45 1,000 0,01555387 0,16169409 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01621637 0,16786691 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01621637 0,16715861 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,01621637 0,16645626 ! cell growth GO:0016049 90 46 1,000 0,01621637 0,16575979 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01621637 0,16506913 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,01689076 0,17122049 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,01757695 0,17744002 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01757695 0,17670981 ! male sex differentiation GO:0046661 93 48 1,000 0,01757695 0,17598559 ! methylation GO:0032259 97 48 1,000 0,01757695 0,17526728 ! response to calcium ion GO:0051592 94 49 1,000 0,01827481 0,1814852 ! JNK cascade GO:0007254 106 49 1,000 0,01827481 0,18075044 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,01827481 0,18002161 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,01898424 0,18625901 ! activation of caspase activity GO:0006919 95 50 1,000 0,01898424 0,18551398 ! regulation of ossification GO:0030278 123 50 1,000 0,01898424 0,18477488 ! viral infectious cycle GO:0019058 104 51 1,000 0,01970513 0,19103026 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,01970513 0,1902752 ! positive regulation of binding GO:0051099 88 52 1,000 0,02043737 0,19656886 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,02043737 0,195798 ! histone modification GO:0016570 104 52 1,000 0,02043737 0,19503317 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02092443 0,19890422 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02092443 0,19813327 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02092443 0,19736828 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02092443 0,19660917 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02092443 0,19585588 ! neuron fate determination GO:0048664 7 5 0,000 0,02092443 0,19510834 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02092443 0,19436648 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02092443 0,19363025 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02092443 0,19289956 ! polyol transport GO:0015791 12 5 0,000 0,02092443 0,19217438 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02092443 0,19145462 ! response to superoxide GO:0000303 10 5 0,000 0,02092443 0,19074024 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02092443 0,19003117 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02092443 0,18932735 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02092443 0,18862873 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02092443 0,18793524 ! female meiosis GO:0007143 10 5 0,000 0,02092443 0,18724683 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02092443 0,18656345 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02092443 0,18588504 ! hypothalamus development GO:0021854 9 5 0,000 0,02092443 0,18521154 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02092443 0,18454291 ! cobalt ion transport GO:0006824 11 5 0,000 0,02092443 0,18387908 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02092443 0,18322002 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02092443 0,18256566 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02092443 0,18191596 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02092443 0,18127087 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02092443 0,18063033 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02092443 0,17999431 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02092443 0,17936275 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02092443 0,17873561 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02092443 0,17811284 ! transposition GO:0032196 9 5 0,000 0,02092443 0,17749439 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02092443 0,17688022 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02092443 0,17627029 ! negative chemotaxis GO:0050919 16 5 0,000 0,02092443 0,17566455 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02092443 0,17506296 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02092443 0,17446548 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02092443 0,17387206 ! behavioral response to pain GO:0048266 10 5 0,000 0,02092443 0,17328266 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02092443 0,17269725 ! Notch receptor processing GO:0007220 11 5 0,000 0,02092443 0,17211577 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02092443 0,1715382 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02092443 0,1709645 ! micturition GO:0060073 9 5 0,000 0,02092443 0,17039462 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02092443 0,16982852 ! copulation GO:0007620 9 5 0,000 0,02092443 0,16926617 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02092443 0,16870754 ! bioluminescence GO:0008218 9 5 0,000 0,02092443 0,16815258 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02092443 0,16760126 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02092443 0,16705354 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02092443 0,1665094 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02092443 0,16596878 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02092443 0,16543167 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02092443 0,16489802 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02092443 0,1643678 ! grooming behavior GO:0007625 6 5 0,000 0,02092443 0,16384098 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02092443 0,16331752 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02092443 0,1627974 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02092443 0,16228059 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02092443 0,16176704 ! response to protozoan GO:0001562 13 5 0,000 0,02092443 0,16125673 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02092443 0,16074964 ! lymph vessel development GO:0001945 10 5 0,000 0,02092443 0,16024572 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02092443 0,15974495 ! endochondral ossification GO:0001958 17 5 0,000 0,02092443 0,1592473 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02092443 0,15875275 ! single strand break repair GO:0000012 8 5 0,000 0,02092443 0,15826125 ! parathyroid gland development GO:0060017 14 5 0,000 0,02092443 0,15777279 ! anagen GO:0042640 7 5 0,000 0,02092443 0,15728734 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02092443 0,15680486 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02092443 0,15632534 ! cytokine secretion GO:0050663 15 5 0,000 0,02092443 0,15584873 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02092443 0,15537503 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02092443 0,1549042 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02092443 0,15443621 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02092443 0,15397104 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02092443 0,15350866 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02092443 0,15304906 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02092443 0,15259219 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02092443 0,15213805 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02092443 0,1516866 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02092443 0,15123782 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02092443 0,1507917 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02092443 0,15034819 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02092443 0,14990729 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02092443 0,14946896 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02092443 0,14903319 ! valine metabolic process GO:0006573 12 5 0,000 0,02092443 0,14859996 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02092443 0,14816923 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02092443 0,147741 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02092443 0,14731523 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02092443 0,14689191 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02092443 0,14647102 ! polyol catabolic process GO:0046174 9 5 0,000 0,02092443 0,14605253 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02092443 0,14563642 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02092443 0,14522268 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02092443 0,14481129 ! muscle cell migration GO:0014812 8 5 0,000 0,02092443 0,14440222 ! mitochondrial fission GO:0000266 8 5 0,000 0,02092443 0,14399545 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02092443 0,14359097 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02092443 0,14318875 ! mRNA transcription GO:0009299 10 5 0,000 0,02092443 0,14278878 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02092443 0,14239104 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02092443 0,14199551 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02092443 0,14160217 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02092443 0,14121101 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02092443 0,140822 ! monocyte activation GO:0042117 10 5 0,000 0,02092443 0,14043512 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02092443 0,14005037 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02092443 0,13966772 ! response to food GO:0032094 6 5 0,000 0,02092443 0,13928715 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02092443 0,13890865 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02092443 0,13853221 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02092443 0,1381578 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02092443 0,1377854 ! forebrain neuron development GO:0021884 13 5 0,000 0,02092443 0,13741501 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02092443 0,13704661 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02092443 0,13668017 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02092443 0,13631569 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02092443 0,13595315 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02092443 0,13559253 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02092443 0,13523382 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02092443 0,134877 ! lipid glycosylation GO:0030259 7 5 0,000 0,02092443 0,13452207 ! nucleobase transport GO:0015851 6 5 0,000 0,02092443 0,13416899 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02092443 0,13381776 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02092443 0,13346837 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02092443 0,13312079 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02092443 0,13277503 ! basic amino acid transport GO:0015802 12 5 0,000 0,02092443 0,13243105 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02092443 0,13208885 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02092443 0,13174841 ! actin nucleation GO:0045010 11 5 0,000 0,02092443 0,13140973 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02092443 0,13107278 ! depurination GO:0045007 5 5 0,000 0,02092443 0,13073756 ! depyrimidination GO:0045008 10 5 0,000 0,02092443 0,13040404 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02092443 0,13007223 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02092443 0,12974209 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02092443 0,12941363 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02092443 0,12908683 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02092443 0,12876167 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02092443 0,12843815 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02092443 0,12811625 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02092443 0,12779596 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02092443 0,12747727 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02092443 0,12716016 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02092443 0,12684463 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02092443 0,12653066 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02092443 0,12621823 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02092443 0,12590735 ! response to arsenic GO:0046685 11 5 0,000 0,02092443 0,125598 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02092443 0,12529016 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02092443 0,12498383 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02092443 0,12467899 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02092443 0,12437563 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02092443 0,12407375 ! response to mercury ion GO:0046689 8 5 0,000 0,02092443 0,12377333 ! response to cadmium ion GO:0046686 7 5 0,000 0,02092443 0,12347436 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02092443 0,12317683 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02092443 0,12288073 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02092443 0,12258605 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02092443 0,12229279 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02092443 0,12200092 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02092443 0,12171044 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02092443 0,12142134 ! decidualization GO:0046697 11 5 0,000 0,02092443 0,12113361 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02092443 0,12084725 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02092443 0,12056223 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02092443 0,12027855 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02092443 0,11999621 ! embryonic cleavage GO:0040016 6 5 0,000 0,02092443 0,11971519 ! peroxisome fission GO:0016559 5 5 0,000 0,02092443 0,11943548 ! histone demethylation GO:0016577 13 5 0,000 0,02092443 0,11915707 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02092443 0,11887996 ! mitotic recombination GO:0006312 9 5 0,000 0,02092443 0,11860414 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02092443 0,11832959 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02092443 0,11805632 ! metaphase plate congression GO:0051310 7 5 0,000 0,02092443 0,1177843 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02092443 0,11751353 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02092443 0,117244 ! enteric nervous system development GO:0048484 8 5 0,000 0,02092443 0,11697571 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02092443 0,11670864 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02092443 0,11644279 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02092443 0,11617815 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02092443 0,1159147 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02092443 0,11565245 ! B cell homeostasis GO:0001782 13 5 0,000 0,02092443 0,11539139 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02092443 0,1151315 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02092443 0,11487277 ! metaphase GO:0051323 11 5 0,000 0,02092443 0,11461521 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02092443 0,1143588 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02092443 0,11410354 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02092443 0,11384941 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02092443 0,11359641 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02092443 0,11334453 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02092443 0,11309377 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02092443 0,11284412 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02092443 0,11259556 ! response to redox state GO:0051775 6 5 0,000 0,02092443 0,1123481 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02092443 0,11210172 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02092443 0,11185642 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02092443 0,11161219 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02092443 0,11136903 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02092443 0,11112692 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02092443 0,11088587 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02092443 0,11064585 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02092443 0,11040688 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02092443 0,11016893 ! striatum development GO:0021756 14 5 0,000 0,02092443 0,10993201 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02092443 0,1096961 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02092443 0,10946121 ! glial cell migration GO:0008347 10 5 0,000 0,02092443 0,10922732 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02092443 0,10899442 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02092443 0,10876252 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02092443 0,1085316 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02092443 0,10830166 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02092443 0,10807269 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02092443 0,10784469 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02092443 0,10761765 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02092443 0,10739156 ! neuroprotection GO:0043526 8 5 0,000 0,02092443 0,10716642 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02092443 0,10694223 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02092443 0,10671897 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02092443 0,10649663 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02092443 0,10627523 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02092443 0,10605474 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02092443 0,10583517 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02092443 0,1056165 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02092443 0,10539873 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02092443 0,10518186 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02092443 0,10496588 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02092443 0,10475079 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02092443 0,10453657 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02092443 0,10432323 ! spindle assembly GO:0051225 6 5 0,000 0,02092443 0,10411076 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02092443 0,10389916 GO:0022011|myelination in the peripheral nervous system, ! protein palmitoylation GO:0018345 12 5 0,000 0,02092443 0,10368841 ! drug metabolic process GO:0017144 7 5 0,000 0,02092443 0,10347851 ! stem cell division GO:0017145 11 5 0,000 0,02092443 0,10326946 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02092443 0,10306126 ! organ regeneration GO:0031100 7 5 0,000 0,02092443 0,10285389 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02092443 0,10264736 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02092443 0,10244165 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,02118085 0,10348965 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,02118085 0,10328308 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 94 54 1,000 0,02193548 0,10674974 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,02270113 0,11025619 ! cell maturation GO:0048469 107 55 1,000 0,02270113 0,11003743 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,02270113 0,10981953 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02347771 0,11335188 ! regulation of DNA replication GO:0006275 105 56 1,000 0,02347771 0,11312831 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,02426512 0,11669228 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,02426512 0,11646302 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 1,000 0,02426512 0,11623466 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,02426512 0,1160072 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02505683 0,11955827 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02505683 0,11932522 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02505683 0,11909307 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02505683 0,11886182 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02505683 0,11863147 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02505683 0,118402 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02505683 0,11817343 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02505683 0,11794573 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02505683 0,11771892 ! response to oxygen radical GO:0000305 11 6 0,000 0,02505683 0,11749297 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02505683 0,11726789 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02505683 0,11704366 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02505683 0,1168203 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02505683 0,11659778 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02505683 0,11637611 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02505683 0,11615529 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02505683 0,1159353 ! forebrain regionalization GO:0021871 9 6 0,000 0,02505683 0,11571614 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02505683 0,1154978 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02505683 0,11528029 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02505683 0,1150636 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02505683 0,11484772 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02505683 0,11463265 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02505683 0,11441839 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02505683 0,11420492 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02505683 0,11399225 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02505683 0,11378036 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02505683 0,11356927 ! malate metabolic process GO:0006108 13 6 0,000 0,02505683 0,11335896 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02505683 0,11314942 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02505683 0,11294066 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02505683 0,11273266 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02505683 0,11252543 ! protein refolding GO:0042026 15 6 0,000 0,02505683 0,11231897 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02505683 0,11211325 ! opsonization GO:0008228 8 6 0,000 0,02505683 0,11190829 ! mating behavior GO:0007617 7 6 0,000 0,02505683 0,11170408 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02505683 0,11150061 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02505683 0,11129788 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02505683 0,11109589 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02505683 0,11089463 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02505683 0,1106941 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02505683 0,11049429 ! toxin metabolic process GO:0009404 11 6 0,000 0,02505683 0,1102952 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02505683 0,11009683 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02505683 0,10989917 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02505683 0,10970222 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02505683 0,10950597 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02505683 0,10931042 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02505683 0,10911557 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02505683 0,10892142 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02505683 0,10872795 ! thymic T cell selection GO:0045061 16 6 0,000 0,02505683 0,10853517 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02505683 0,10834307 ! protein lipoylation GO:0009249 10 6 0,000 0,02505683 0,10815165 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02505683 0,10796091 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02505683 0,10777084 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02505683 0,10758143 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02505683 0,10739269 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02505683 0,10720462 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02505683 0,1070172 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02505683 0,10683043 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02505683 0,10664431 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02505683 0,10645885 ! hyperosmotic response GO:0006972 10 6 0,000 0,02505683 0,10627402 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02505683 0,10608984 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02505683 0,10590629 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02505683 0,10572338 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02505683 0,1055411 ! urea metabolic process GO:0019627 7 6 0,000 0,02505683 0,10535944 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02505683 0,10517841 ! neutrophil activation GO:0042119 7 6 0,000 0,02505683 0,104998 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02505683 0,10481821 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02505683 0,10463904 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02505683 0,10446047 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02505683 0,10428251 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02505683 0,10410516 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02505683 0,10392841 ! neuron apoptosis GO:0051402 15 6 0,000 0,02505683 0,10375226 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02505683 0,10357671 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02505683 0,10340175 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02505683 0,10322738 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02505683 0,1030536 ! carnitine transport GO:0015879 10 6 0,000 0,02505683 0,1028804 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02505683 0,10270778 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02505683 0,10253574 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02505683 0,10236427 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02505683 0,10219338 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02505683 0,10202306 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02505683 0,1018533 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02505683 0,10168411 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02505683 0,10151548 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02505683 0,10134741 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02505683 0,10117989 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02505683 0,10101293 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02505683 0,10084652 ! response to UV-C GO:0010225 14 6 0,000 0,02505683 0,10068065 ! astrocyte development GO:0014002 16 6 0,000 0,02505683 0,10051533 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02505683 0,10035055 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02505683 0,10018631 ! interaction with symbiont GO:0051702 14 6 0,000 0,02505683 0,10002261 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02505683 0,09985944 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02505683 0,0996968 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02505683 0,09953469 ! response to copper ion GO:0046688 10 6 0,000 0,02505683 0,09937311 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02505683 0,09921205 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02505683 0,09905151 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02505683 0,0988915 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02505683 0,09873199 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02505683 0,098573 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02505683 0,09841453 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02505683 0,09825656 ! hair follicle maturation GO:0048820 8 6 0,000 0,02505683 0,0980991 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02505683 0,09794214 ! Schwann cell development GO:0014044 15 6 0,000 0,02505683 0,09778568 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02505683 0,09762972 ! response to pheromone GO:0019236 6 6 0,000 0,02505683 0,09747426 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02505683 0,09731929 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02505683 0,09716482 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02505683 0,09701083 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02505683 0,09685734 ! subpallium development GO:0021544 15 6 0,000 0,02505683 0,09670432 ! neural tube patterning GO:0021532 8 6 0,000 0,02505683 0,09655179 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02505683 0,09639974 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02505683 0,09624817 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02505683 0,09609707 ! G2 phase GO:0051319 16 6 0,000 0,02505683 0,09594645 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02505683 0,0957963 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02505683 0,09564662 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02505683 0,0954974 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02505683 0,09534865 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02505683 0,09520037 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02505683 0,09505254 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02505683 0,09490517 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02505683 0,09475826 ! receptor internalization GO:0031623 11 6 0,000 0,02505683 0,0946118 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02505683 0,0944658 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02505683 0,09432024 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02505683 0,09417513 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02505683 0,09403047 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02505683 0,09388625 ! protein deubiquitination GO:0016579 16 6 0,000 0,02505683 0,09374247 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02505683 0,09359914 ! protein destabilization GO:0031648 9 6 0,000 0,02505683 0,09345624 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02505683 0,09331377 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02505683 0,09317174 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02505683 0,09303015 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02505683 0,09288898 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02505683 0,09274824 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02505683 0,09260792 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02505683 0,09246803 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02505683 0,09232856 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02505683 0,09218951 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02505683 0,09205088 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02505683 0,09191267 ! neural plate development GO:0001840 9 6 0,000 0,02505683 0,09177487 ! catecholamine transport GO:0051937 9 6 0,000 0,02505683 0,09163748 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02505683 0,0915005 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02505683 0,09136393 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02505683 0,09122777 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02505683 0,09109202 ! maternal placenta development GO:0001893 12 6 0,000 0,02505683 0,09095667 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02505683 0,09082172 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02505683 0,09068716 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02505683 0,09055301 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02505683 0,09041926 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02505683 0,09028589 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02505683 0,09015292 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02505683 0,09002035 GO:0055081|anion homeostasis, ! regulation of actin filament length GO:0030832 118 58 1,000 0,02506324 0,08991114 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,02506324 0,08977931 ! aging GO:0007568 112 58 1,000 0,02506324 0,08964786 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,02506324 0,0895168 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,02506324 0,08938612 ! establishment of organelle localization GO:0051656 122 59 1,000 0,02587197 0,09213591 ! lipid modification GO:0030258 112 60 1,000 0,02669122 0,09491508 ! DNA catabolic process GO:0006308 94 60 1,000 0,02669122 0,09477712 ! kidney development GO:0001822 133 60 1,000 0,02669122 0,09463956 ! regulation of cellular component size GO:0032535 125 61 1,000 0,02752088 0,09743988 ! regulation of heart contraction GO:0008016 123 61 1,000 0,02752088 0,09729887 ! camera-type eye development GO:0043010 126 61 1,000 0,02752088 0,09715826 ! viral reproductive process GO:0022415 132 62 1,000 0,02836085 0,09997917 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,02836085 0,09983511 ! tRNA transcription GO:0009304 17 7 0,000 0,0291719 0,10254239 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,0291719 0,10239506 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,0291719 0,10224815 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0291719 0,10210166 ! regulation of helicase activity GO:0051095 16 7 0,000 0,0291719 0,10195559 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,0291719 0,10180994 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,0291719 0,10166471 ! sleep GO:0030431 16 7 0,000 0,0291719 0,10151989 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0291719 0,10137548 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,0291719 0,10123148 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0291719 0,10108789 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,0291719 0,1009447 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0291719 0,10080192 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0291719 0,10065955 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,0291719 0,10051757 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0291719 0,100376 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,0291719 0,10023482 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,0291719 0,10009405 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0291719 0,09995366 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,0291719 0,09981367 ! glycolipid transport GO:0046836 11 7 0,000 0,0291719 0,09967407 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0291719 0,09953486 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,0291719 0,09939604 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0291719 0,0992576 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0291719 0,09911956 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,0291719 0,09898189 ! mRNA stabilization GO:0048255 18 7 0,000 0,0291719 0,0988446 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,0291719 0,0987077 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,0291719 0,09857118 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,0291719 0,09843503 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,0291719 0,09829926 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,0291719 0,09816386 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0291719 0,09802883 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0291719 0,09789418 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,0291719 0,09775989 ! rhythmic behavior GO:0007622 17 7 0,000 0,0291719 0,09762597 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,0291719 0,09749242 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,0291719 0,09735924 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,0291719 0,09722641 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,0291719 0,09709395 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0291719 0,09696185 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,0291719 0,09683011 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0291719 0,09669872 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,0291719 0,0965677 ! mechanosensory behavior GO:0007638 16 7 0,000 0,0291719 0,09643702 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,0291719 0,0963067 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,0291719 0,09617673 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,0291719 0,09604712 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,0291719 0,09591785 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0291719 0,09578892 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0291719 0,09566035 ! spinal cord patterning GO:0021511 14 7 0,000 0,0291719 0,09553212 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,0291719 0,09540423 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,0291719 0,09527668 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,0291719 0,09514948 ! adrenal gland development GO:0030325 17 7 0,000 0,0291719 0,09502261 ! cysteine metabolic process GO:0006534 13 7 0,000 0,0291719 0,09489609 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,0291719 0,09476989 ! ovulation GO:0030728 10 7 0,000 0,0291719 0,09464404 ! adenohypophysis development GO:0021984 11 7 0,000 0,0291719 0,09451851 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,0291719 0,09439332 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,0291719 0,09426847 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,0291719 0,09414394 ! microtubule nucleation GO:0007020 21 7 0,000 0,0291719 0,09401974 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0291719 0,09389586 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,0291719 0,09377232 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0291719 0,09364909 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,0291719 0,09352619 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,0291719 0,09340362 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0291719 0,09328136 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,0291719 0,09315942 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,0291719 0,09303781 ! galactose metabolic process GO:0006012 13 7 0,000 0,0291719 0,09291651 ! vesicle fusion GO:0006906 20 7 0,000 0,0291719 0,09279552 ! response to dietary excess GO:0002021 8 7 0,000 0,0291719 0,09267485 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0291719 0,09255449 ! intracellular pH reduction GO:0051452 13 7 0,000 0,0291719 0,09243445 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0291719 0,09231472 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,0291719 0,09219529 ! organ growth GO:0035265 15 7 0,000 0,0291719 0,09207618 ! nucleoside transport GO:0015858 11 7 0,000 0,0291719 0,09195737 ! nucleoside salvage GO:0043174 11 7 0,000 0,0291719 0,09183887 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,0291719 0,09172067 ! male sex determination GO:0030238 15 7 0,000 0,0291719 0,09160278 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,0291719 0,09148519 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,0291719 0,0913679 ! parturition GO:0007567 16 7 0,000 0,0291719 0,09125091 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,0291719 0,09113422 ! rRNA modification GO:0000154 14 7 0,000 0,0291719 0,09101783 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,0291719 0,09090173 ! spindle checkpoint GO:0031577 16 7 0,000 0,0291719 0,09078594 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,0291719 0,09067043 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,0291719 0,09055522 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,0291719 0,0904403 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0291719 0,09032568 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,0291719 0,09021134 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,0291719 0,09009729 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,0291719 0,08998354 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0291719 0,08987006 ! fibrinolysis GO:0042730 11 7 0,000 0,0291719 0,08975688 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,0291719 0,08964397 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,0291719 0,08953136 ! eating behavior GO:0042755 8 7 0,000 0,0291719 0,08941902 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0291719 0,08930697 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0291719 0,08919519 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,0291719 0,0890837 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,0291719 0,08897248 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0291719 0,08886155 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,0291719 0,08875088 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0291719 0,0886405 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,0291719 0,08853039 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,0291719 0,08842055 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,0291719 0,08831098 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,0291719 0,08820168 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0291719 0,08809266 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,0291719 0,0879839 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0291719 0,08787541 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0291719 0,08776719 ! histone ubiquitination GO:0016574 9 7 0,000 0,0291719 0,08765924 ! regulation of meiosis GO:0040020 12 7 0,000 0,0291719 0,08755155 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,0291719 0,08744412 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0291719 0,08733696 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,0291719 0,08723006 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0291719 0,08712342 ! membrane to membrane docking GO:0022614 14 7 0,000 0,0291719 0,08701705 ! transcription termination GO:0006353 14 7 0,000 0,0291719 0,08691093 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0291719 0,08680507 ! anaphase GO:0051322 18 7 0,000 0,0291719 0,08669946 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,0291719 0,08659412 ! axonal fasciculation GO:0007413 19 7 0,000 0,0291719 0,08648903 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,0291719 0,08638419 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,0291719 0,08627961 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,0291719 0,08617528 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,0291719 0,08607121 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0291719 0,08596738 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0291719 0,08586381 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0291719 0,08576048 ! antibiotic transport GO:0042891 9 7 0,000 0,0291719 0,0856574 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0291719 0,08555457 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,0291719 0,08545199 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,0291719 0,08534965 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,0291719 0,08524756 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,0291719 0,08514571 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,0291719 0,08504411 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,0291719 0,08494274 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0291719 0,08484162 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0291719 0,08474074 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,0291719 0,0846401 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,0291719 0,08453969 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,0291719 0,08443953 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,0291719 0,0843396 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,0291719 0,08423991 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,0291719 0,08414045 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,0291719 0,08404123 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,0291719 0,08394224 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,0291719 0,08384348 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0291719 0,08374496 ! muscle adaptation GO:0043500 13 7 0,000 0,0291719 0,08364667 ! embryonic heart tube development GO:0035050 14 7 0,000 0,0291719 0,08354861 ! retina homeostasis GO:0001895 12 7 0,000 0,0291719 0,08345077 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,0291719 0,08335317 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,0291719 0,08325579 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,0291719 0,08315865 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,0291719 0,08306173 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,02921103 0,08307631 ! regulation of mitosis GO:0007088 112 63 1,000 0,02921103 0,08297971 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,02921103 0,08288333 ! gonad development GO:0008406 115 66 1,000 0,03182182 0,09018645 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,03271185 0,09260144 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,03271185 0,09249426 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03326972 0,09396293 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03326972 0,09385443 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03326972 0,09374617 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03326972 0,09363817 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03326972 0,09353042 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03326972 0,09342291 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03326972 0,09331565 ! male meiosis GO:0007140 9 8 0,000 0,03326972 0,09320864 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03326972 0,09310187 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03326972 0,09299535 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03326972 0,09288907 ! meiotic prophase I GO:0007128 14 8 0,000 0,03326972 0,09278303 ! response to zinc ion GO:0010043 12 8 0,000 0,03326972 0,09267723 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03326972 0,09257168 ! oligopeptide transport GO:0006857 16 8 0,000 0,03326972 0,09246636 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03326972 0,09236129 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03326972 0,09225645 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03326972 0,09215185 ! signal peptide processing GO:0006465 12 8 0,000 0,03326972 0,09204749 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03326972 0,09194336 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03326972 0,09183947 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03326972 0,09173582 ! succinate metabolic process GO:0006105 17 8 0,000 0,03326972 0,09163239 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03326972 0,0915292 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03326972 0,09142625 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03326972 0,09132352 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03326972 0,09122103 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03326972 0,09111876 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03326972 0,09101672 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03326972 0,09091491 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03326972 0,09081333 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03326972 0,09071198 ! reflex GO:0060004 17 8 0,000 0,03326972 0,09061085 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03326972 0,09050995 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03326972 0,09040927 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03326972 0,09030881 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03326972 0,09020858 ! pigment granule organization GO:0048753 17 8 0,000 0,03326972 0,09010857 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03326972 0,09000879 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03326972 0,08990922 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03326972 0,08980987 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03326972 0,08971074 ! histidine catabolic process GO:0006548 10 8 0,000 0,03326972 0,08961183 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03326972 0,08951314 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03326972 0,08941467 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03326972 0,08931641 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03326972 0,08921837 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03326972 0,08912054 ! melanin metabolic process GO:0006582 17 8 0,000 0,03326972 0,08902293 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03326972 0,08892553 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03326972 0,08882834 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03326972 0,08873137 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03326972 0,08863461 ! macrophage activation GO:0042116 13 8 0,000 0,03326972 0,08853805 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03326972 0,08844171 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03326972 0,08834558 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03326972 0,08824966 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03326972 0,08815394 ! purine salvage GO:0043101 12 8 0,000 0,03326972 0,08805843 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03326972 0,08796313 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03326972 0,08786804 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03326972 0,08777315 ! osteoblast development GO:0002076 17 8 0,000 0,03326972 0,08767846 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03326972 0,08758398 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03326972 0,0874897 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03326972 0,08739563 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03326972 0,08730175 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03326972 0,08720808 ! response to UV-B GO:0010224 17 8 0,000 0,03326972 0,08711461 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03326972 0,08702134 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03326972 0,08692827 ! intermediate filament organization GO:0045109 12 8 0,000 0,03326972 0,0868354 ! cellular extravasation GO:0045123 13 8 0,000 0,03326972 0,08674272 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03326972 0,08665025 ! response to antibiotic GO:0046677 11 8 0,000 0,03326972 0,08655797 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03326972 0,08646589 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03326972 0,086374 ! DNA topological change GO:0006265 12 8 0,000 0,03326972 0,08628231 ! response to tropane GO:0014073 15 8 0,000 0,03326972 0,08619081 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,03326972 0,08609951 ! melanosome transport GO:0032402 13 8 0,000 0,03326972 0,0860084 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03326972 0,08591748 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03326972 0,08582675 ! mast cell activation GO:0045576 14 8 0,000 0,03326972 0,08573622 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03326972 0,08564587 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03326972 0,08555572 ! gas homeostasis GO:0033483 14 8 0,000 0,03326972 0,08546576 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03326972 0,08537598 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03326972 0,08528639 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03326972 0,085197 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03326972 0,08510778 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03326972 0,08501876 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03326972 0,08492992 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03326972 0,08484127 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03326972 0,0847528 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03326972 0,08466451 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03326972 0,08457641 ! response to tumor cell GO:0002347 16 8 0,000 0,03326972 0,0844885 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03326972 0,08440076 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03326972 0,08431321 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03326972 0,08422584 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03326972 0,08413865 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03326972 0,08405164 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03326972 0,08396481 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03326972 0,08387816 ! hormone catabolic process GO:0042447 17 8 0,000 0,03326972 0,08379168 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03326972 0,08370539 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03326972 0,08361927 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03326972 0,08353333 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03326972 0,08344757 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03326972 0,08336198 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03326972 0,08327657 ! adult feeding behavior GO:0008343 10 8 0,000 0,03326972 0,08319133 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03326972 0,08310627 ! ATP catabolic process GO:0006200 11 8 0,000 0,03326972 0,08302138 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03326972 0,08293667 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03326972 0,08285212 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03326972 0,08276775 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03326972 0,08268355 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03326972 0,08259953 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03326972 0,08251567 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03326972 0,08243198 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03326972 0,08234846 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03326972 0,08226511 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03326972 0,08218193 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03326972 0,08209892 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03326972 0,08201608 ! protein prenylation GO:0018342 21 8 0,000 0,03326972 0,0819334 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03326972 0,08185089 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03326972 0,08176854 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03326972 0,08168637 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03326972 0,08160435 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,03361158 0,08236018 ! viral reproduction GO:0016032 142 68 1,000 0,03361158 0,08227766 ! cell projection assembly GO:0030031 138 68 1,000 0,03361158 0,0821953 ! lung development GO:0030324 165 69 1,000 0,03452094 0,08433466 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,03452094 0,08425041 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,03452094 0,08416633 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,03452094 0,08408241 ! developmental maturation GO:0021700 128 69 1,000 0,03452094 0,08399867 ! germ cell development GO:0007281 133 70 1,000 0,03543982 0,08614874 ! appendage morphogenesis GO:0035107 150 72 1,000 0,03730577 0,09059443 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 0,03730577 0,09050447 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,03730577 0,09041468 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,03730577 0,09032507 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,03730577 0,09023564 ! axon extension GO:0048675 16 9 0,000 0,03735036 0,09025414 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03735036 0,09016495 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03735036 0,09007594 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03735036 0,08998711 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03735036 0,08989845 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03735036 0,08980997 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03735036 0,08972166 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03735036 0,08963353 ! reproductive behavior GO:0019098 22 9 0,000 0,03735036 0,08954557 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03735036 0,08945778 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03735036 0,08937016 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03735036 0,08928271 ! UTP metabolic process GO:0046051 10 9 0,000 0,03735036 0,08919544 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03735036 0,08910833 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03735036 0,0890214 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03735036 0,08893463 ! artery development GO:0060840 25 9 0,000 0,03735036 0,08884803 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03735036 0,08876161 ! regulation of glycolysis GO:0006110 20 9 0,000 0,03735036 0,08867535 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03735036 0,08858925 ! equilibrioception GO:0050957 20 9 0,000 0,03735036 0,08850333 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03735036 0,08841757 ! chemosensory behavior GO:0007635 21 9 0,000 0,03735036 0,08833198 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03735036 0,08824655 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03735036 0,08816129 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03735036 0,08807619 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03735036 0,08799125 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03735036 0,08790648 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03735036 0,08782188 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03735036 0,08773743 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03735036 0,08765315 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03735036 0,08756903 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03735036 0,08748507 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03735036 0,08740128 ! protein targeting to ER GO:0045047 25 9 0,000 0,03735036 0,08731764 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03735036 0,08723416 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03735036 0,08715084 ! T cell selection GO:0045058 27 9 0,000 0,03735036 0,08706768 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03735036 0,08698468 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03735036 0,08690184 ! endosome organization GO:0007032 20 9 0,000 0,03735036 0,08681915 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03735036 0,08673663 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03735036 0,08665426 ! mannose metabolic process GO:0006013 13 9 0,000 0,03735036 0,08657204 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03735036 0,08648998 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03735036 0,08640808 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03735036 0,08632633 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03735036 0,08624474 ! receptor clustering GO:0043113 20 9 0,000 0,03735036 0,0861633 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03735036 0,08608201 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03735036 0,08600088 ! retinol metabolic process GO:0042572 20 9 0,000 0,03735036 0,0859199 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03735036 0,08583907 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03735036 0,08575839 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03735036 0,08567787 ! macrophage differentiation GO:0030225 15 9 0,000 0,03735036 0,0855975 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03735036 0,08551727 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03735036 0,0854372 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03735036 0,08535728 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03735036 0,08527751 ! response to amine stimulus GO:0014075 13 9 0,000 0,03735036 0,08519788 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03735036 0,08511841 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03735036 0,08503908 ! erythrocyte development GO:0048821 17 9 0,000 0,03735036 0,0849599 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03735036 0,08488087 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03735036 0,08480198 ! renal water homeostasis GO:0003091 15 9 0,000 0,03735036 0,08472324 ! postreplication repair GO:0006301 25 9 0,000 0,03735036 0,08464465 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03735036 0,0845662 ! icosanoid secretion GO:0032309 15 9 0,000 0,03735036 0,0844879 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03735036 0,08440974 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03735036 0,08433173 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03735036 0,08425386 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03735036 0,08417614 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03735036 0,08409855 ! sterol catabolic process GO:0016127 14 9 0,000 0,03735036 0,08402112 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03735036 0,08394382 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03735036 0,08386666 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03735036 0,08378965 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03735036 0,08371278 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03735036 0,08363605 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03735036 0,08355946 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03735036 0,08348301 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03735036 0,0834067 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03735036 0,08333053 ! purine base metabolic process GO:0006144 25 9 0,000 0,03735036 0,0832545 ! pigment granule transport GO:0051904 17 9 0,000 0,03735036 0,08317861 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03735036 0,08310285 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03735036 0,08302723 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03735036 0,08295176 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03735036 0,08287641 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03735036 0,08280121 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03735036 0,08272614 ! mitochondrion localization GO:0051646 18 9 0,000 0,03735036 0,08265121 ! appendage development GO:0048736 151 73 1,000 0,03825265 0,08457125 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 0,03920868 0,08660651 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,03920868 0,08652828 ! respiratory system development GO:0060541 175 74 1,000 0,03920868 0,08645018 ! organelle localization GO:0051640 155 74 1,000 0,03920868 0,08637223 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,04017376 0,08841846 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,0411478 0,09048071 ! learning or memory GO:0007611 161 76 1,000 0,0411478 0,09039934 ! regulation of blood pressure GO:0008217 134 76 1,000 0,0411478 0,09031812 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,0411478 0,09023704 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04141389 0,09073913 ! regulation of developmental growth GO:0048638 16 10 0,000 0,04141389 0,09065782 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04141389 0,09057666 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04141389 0,09049564 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04141389 0,09041477 ! associative learning GO:0008306 21 10 0,000 0,04141389 0,09033404 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04141389 0,09025346 ! phosphate transport GO:0006817 24 10 0,000 0,04141389 0,09017302 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04141389 0,09009272 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04141389 0,09001257 ! CTP metabolic process GO:0046036 11 10 0,000 0,04141389 0,08993256 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04141389 0,08985269 ! GTP metabolic process GO:0046039 11 10 0,000 0,04141389 0,08977296 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04141389 0,08969338 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04141389 0,08961393 ! social behavior GO:0035176 29 10 0,000 0,04141389 0,08953463 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04141389 0,08945546 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04141389 0,08937644 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04141389 0,08929755 ! androgen metabolic process GO:0008209 17 10 0,000 0,04141389 0,08921881 ! phospholipid efflux GO:0033700 19 10 0,000 0,04141389 0,0891402 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04141389 0,08906173 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04141389 0,0889834 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04141389 0,08890521 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04141389 0,08882715 ! lung alveolus development GO:0048286 26 10 0,000 0,04141389 0,08874924 ! pathogenesis GO:0009405 17 10 0,000 0,04141389 0,08867145 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04141389 0,08859381 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04141389 0,0885163 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04141389 0,08843892 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04141389 0,08836168 ! endoderm development GO:0007492 18 10 0,000 0,04141389 0,08828458 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04141389 0,08820761 ! arginine catabolic process GO:0006527 17 10 0,000 0,04141389 0,08813077 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04141389 0,08805407 ! proline metabolic process GO:0006560 13 10 0,000 0,04141389 0,0879775 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04141389 0,08790107 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04141389 0,08782476 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04141389 0,08774859 ! V(D)J recombination GO:0033151 34 10 0,000 0,04141389 0,08767256 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04141389 0,08759665 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04141389 0,08752087 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04141389 0,08744523 ! B cell proliferation GO:0042100 19 10 0,000 0,04141389 0,08736971 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04141389 0,08729433 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04141389 0,08721908 ! multicellular organism growth GO:0035264 19 10 0,000 0,04141389 0,08714395 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04141389 0,08706896 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04141389 0,08699409 ! ruffle organization GO:0031529 17 10 0,000 0,04141389 0,08691935 ! epithelial cell development GO:0002064 21 10 0,000 0,04141389 0,08684475 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04141389 0,08677026 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04141389 0,08669591 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04141389 0,08662169 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04141389 0,08654759 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04141389 0,08647361 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04141389 0,08639977 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,04141389 0,08632605 ! motor axon guidance GO:0008045 22 10 0,000 0,04141389 0,08625245 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04141389 0,08617899 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04141389 0,08610564 ! protein heterooligomerization GO:0051291 17 10 0,000 0,04141389 0,08603242 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04141389 0,08595933 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04141389 0,08588636 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04141389 0,08581351 ! segment specification GO:0007379 15 10 0,000 0,04141389 0,08574079 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04141389 0,08566819 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04141389 0,08559571 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04141389 0,08552335 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04141389 0,08545112 ! response to dsRNA GO:0043331 23 10 0,000 0,04141389 0,08537901 ! DNA ligation GO:0006266 18 10 0,000 0,04141389 0,08530702 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04141389 0,08523515 ! melanosome localization GO:0032400 16 10 0,000 0,04141389 0,08516341 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04141389 0,08509178 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04141389 0,08502028 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04141389 0,08494889 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04141389 0,08487762 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04141389 0,08480648 ! induction of an organ GO:0001759 17 10 0,000 0,04141389 0,08473545 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04141389 0,08466454 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04141389 0,08459375 ! protein sumoylation GO:0016925 17 10 0,000 0,04141389 0,08452308 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04141389 0,08445253 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04141389 0,08438209 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04141389 0,08431177 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04141389 0,08424157 ! salivary gland development GO:0007431 28 10 0,000 0,04141389 0,08417149 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04141389 0,08410152 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04141389 0,08403167 ! midbrain development GO:0030901 14 10 0,000 0,04141389 0,08396193 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04141389 0,08389231 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04141389 0,08382281 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04141389 0,08375342 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04141389 0,08368414 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04141389 0,08361498 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04141389 0,08354594 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04141389 0,083477 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04141389 0,08340819 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,04141389 0,08333948 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,04141389 0,08327089 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04141389 0,08320241 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04141389 0,08313404 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04141389 0,08306579 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04141389 0,08299764 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04141389 0,08292961 ! response to nicotine GO:0035094 20 10 0,000 0,04141389 0,08286169 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04141389 0,08279389 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04141389 0,08272619 ! amine catabolic process GO:0009310 136 77 1,000 0,0421307 0,0840893 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,0421307 0,08402066 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,0421307 0,08395213 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,0421307 0,08388371 ! antigen processing and presentation GO:0019882 117 78 1,000 0,04312239 0,08578827 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,04312239 0,08571846 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,04412276 0,08763569 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,04412276 0,0875645 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,04412276 0,08749343 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,04513173 0,08942158 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,04513173 0,08934912 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,04513173 0,08927677 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04546038 0,08985413 ! respiratory burst GO:0045730 17 11 0,000 0,04546038 0,08978149 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04546038 0,08970897 ! neuron fate specification GO:0048665 18 11 0,000 0,04546038 0,08963656 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04546038 0,08956427 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04546038 0,0894921 ! thyroid gland development GO:0030878 26 11 0,000 0,04546038 0,08942005 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,04546038 0,08934811 ! synapsis GO:0007129 14 11 0,000 0,04546038 0,08927629 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04546038 0,08920458 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04546038 0,08913299 ! response to pain GO:0048265 27 11 0,000 0,04546038 0,08906151 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04546038 0,08899014 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04546038 0,08891889 ! blood vessel remodeling GO:0001974 30 11 0,000 0,04546038 0,08884776 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,04546038 0,08877674 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,04546038 0,08870583 ! bone resorption GO:0045453 16 11 0,000 0,04546038 0,08863504 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04546038 0,08856435 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04546038 0,08849378 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04546038 0,08842333 ! histidine metabolic process GO:0006547 22 11 0,000 0,04546038 0,08835298 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04546038 0,08828275 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04546038 0,08821263 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04546038 0,08814262 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,04546038 0,08807272 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04546038 0,08800293 ! UV protection GO:0009650 20 11 0,000 0,04546038 0,08793325 ! adult heart development GO:0007512 16 11 0,000 0,04546038 0,08786369 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04546038 0,08779423 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04546038 0,08772488 ! macroautophagy GO:0016236 19 11 0,000 0,04546038 0,08765564 ! temperature homeostasis GO:0001659 18 11 0,000 0,04546038 0,08758651 ! behavioral fear response GO:0001662 27 11 0,000 0,04546038 0,08751749 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 0,000 0,04546038 0,08744858 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04546038 0,08737978 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04546038 0,08731108 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04546038 0,0872425 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04546038 0,08717402 ! regulation of organ growth GO:0046620 14 11 0,000 0,04546038 0,08710565 ! pigment granule localization GO:0051875 20 11 0,000 0,04546038 0,08703738 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04546038 0,08696922 ! vasoconstriction GO:0042310 20 11 0,000 0,04546038 0,08690117 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04546038 0,08683323 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04546038 0,08676539 ! embryonic axis specification GO:0000578 19 11 0,000 0,04546038 0,08669766 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04546038 0,08663003 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04546038 0,08656251 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04546038 0,08649509 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04546038 0,08642778 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04546038 0,08636058 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04546038 0,08629347 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04546038 0,08622647 ! prophase GO:0051324 17 11 0,000 0,04546038 0,08615958 ! neuroblast proliferation GO:0007405 25 11 0,000 0,04546038 0,08609279 ! nucleosome positioning GO:0016584 15 11 0,000 0,04546038 0,0860261 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04546038 0,08595952 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04546038 0,08589304 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04546038 0,08582666 ! apical protein localization GO:0045176 18 11 0,000 0,04546038 0,08576039 ! acid secretion GO:0046717 20 11 0,000 0,04546038 0,08569421 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04546038 0,08562814 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04546038 0,08556217 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,04546038 0,0854963 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04546038 0,08543054 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04546038 0,08536487 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04546038 0,08529931 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04546038 0,08523384 ! cholesterol efflux GO:0033344 21 11 0,000 0,04546038 0,08516848 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04546038 0,08510322 ! oocyte development GO:0048599 20 11 0,000 0,04546038 0,08503805 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04546038 0,08497299 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04546038 0,08490803 ! embryonic gut development GO:0048566 19 11 0,000 0,04546038 0,08484316 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04546038 0,0847784 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04546038 0,08471373 ! activation of innate immune response GO:0002218 16 11 0,000 0,04546038 0,08464916 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04546038 0,08458469 ! prepulse inhibition GO:0060134 18 11 0,000 0,04546038 0,08452032 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04546038 0,08445605 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04546038 0,08439187 ! nucleus localization GO:0051647 22 11 0,000 0,04546038 0,08432779 ! meiosis GO:0007126 143 81 1,000 0,0461492 0,0855406 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 1,000 0,0461492 0,08547574 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,0461492 0,08541099 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,0471751 0,08724358 ! protein import into nucleus GO:0006606 174 82 1,000 0,0471751 0,08717759 ! meiotic cell cycle GO:0051321 144 82 1,000 0,0471751 0,08711169 ! response to drug GO:0042493 149 83 1,000 0,04820933 0,08895422 ! response to oxygen levels GO:0070482 183 83 1,000 0,04820933 0,08888708 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,04820933 0,08882005 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,04820933 0,08875312 ! nuclear import GO:0051170 177 83 1,000 0,04820933 0,08868628 ! response to metal ion GO:0010038 158 84 1,000 0,0492518 0,09053585 ! regulation of ligase activity GO:0051340 147 84 1,000 0,0492518 0,09046777 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0494899 0,09083683 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0494899 0,09076863 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,0494899 0,09070054 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0494899 0,09063255 ! virus-host interaction GO:0019048 30 12 0,000 0,0494899 0,09056466 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0494899 0,09049687 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0494899 0,09042918 ! protein complex disassembly GO:0043241 28 12 0,000 0,0494899 0,0903616 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0494899 0,09029411 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0494899 0,09022673 ! hippocampus development GO:0021766 29 12 0,000 0,0494899 0,09015945 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0494899 0,09009226 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0494899 0,09002518 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0494899 0,0899582 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0494899 0,08989131 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0494899 0,08982453 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0494899 0,08975785 ! drug transport GO:0015893 16 12 0,000 0,0494899 0,08969126 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0494899 0,08962477 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0494899 0,08955838 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0494899 0,08949209 ! focal adhesion formation GO:0048041 37 12 0,000 0,0494899 0,0894259 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0494899 0,08935981 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0494899 0,08929381 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0494899 0,08922791 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0494899 0,08916211 ! lipid digestion GO:0044241 21 12 0,000 0,0494899 0,0890964 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0494899 0,08903079 ! entry into host cell GO:0030260 34 12 0,000 0,0494899 0,08896528 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0494899 0,08889987 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0494899 0,08883455 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0494899 0,08876932 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0494899 0,08870419 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0494899 0,08863916 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0494899 0,08857423 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0494899 0,08850938 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0494899 0,08844464 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0494899 0,08837998 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0494899 0,08831543 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0494899 0,08825096 ! cranial nerve development GO:0021545 23 12 0,000 0,0494899 0,08818659 ! fucose catabolic process GO:0019317 25 12 0,000 0,0494899 0,08812232 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0494899 0,08805813 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0494899 0,08799404 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0494899 0,08793005 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0494899 0,08786615 ! zymogen activation GO:0031638 18 12 0,000 0,0494899 0,08780234 ! T cell homeostasis GO:0043029 28 12 0,000 0,0494899 0,08773862 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0494899 0,08767499 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0494899 0,08761146 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0494899 0,08754802 ! oocyte differentiation GO:0009994 21 12 0,000 0,0494899 0,08748467 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0494899 0,08742142 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0494899 0,08735825 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,0494899 0,08729518 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0494899 0,08723219 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0494899 0,0871693 ! defense response to fungus GO:0050832 15 12 0,000 0,0494899 0,0871065 ! developmental induction GO:0031128 22 12 0,000 0,0494899 0,08704379 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0494899 0,08698116 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0494899 0,08691863 ! response to cold GO:0009409 17 12 0,000 0,0494899 0,08685619 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0494899 0,08679384 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0494899 0,08673158 ! localization within membrane GO:0051668 26 12 0,000 0,0494899 0,0866694 ! cholesterol metabolic process GO:0008203 148 85 1,000 0,05030242 0,08802924 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,05030242 0,08796623 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,05136112 0,08975337 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,0524278 0,09155191 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,05350238 0,09336165 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05350252 0,09329526 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05350252 0,09322871 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05350252 0,09316226 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05350252 0,09309591 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05350252 0,09302965 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05350252 0,09296348 ! peroxisomal transport GO:0043574 28 13 0,000 0,05350252 0,09289741 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05350252 0,09283143 ! cartilage condensation GO:0001502 22 13 0,000 0,05350252 0,09276555 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05350252 0,09269976 ! organelle fusion GO:0048284 36 13 0,000 0,05350252 0,09263406 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05350252 0,09256845 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05350252 0,09250294 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05350252 0,09243752 ! endocrine pancreas development GO:0031018 25 13 0,000 0,05350252 0,09237219 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05350252 0,09230696 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05350252 0,09224182 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05350252 0,09217677 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05350252 0,09211181 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05350252 0,09204694 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05350252 0,09198216 ! methionine metabolic process GO:0006555 31 13 0,000 0,05350252 0,09191748 ! plasma membrane organization GO:0007009 27 13 0,000 0,05350252 0,09185288 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05350252 0,09178838 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05350252 0,09172397 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05350252 0,09165965 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05350252 0,09159541 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,05350252 0,09153127 ! cytokine metabolic process GO:0042107 24 13 0,000 0,05350252 0,09146722 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05350252 0,09140326 ! exocrine system development GO:0035272 34 13 0,000 0,05350252 0,09133938 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05350252 0,0912756 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05350252 0,0912119 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05350252 0,0911483 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,05350252 0,09108478 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,05350252 0,09102135 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05350252 0,09095801 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05350252 0,09089475 ! protein homotetramerization GO:0051289 24 13 0,000 0,05350252 0,09083159 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05350252 0,09076851 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05350252 0,09070552 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05350252 0,09064262 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05350252 0,0905798 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05350252 0,09051707 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05350252 0,09045443 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,05350252 0,09039188 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05350252 0,09032941 ! histone methylation GO:0016571 29 13 0,000 0,05350252 0,09026703 ! gland morphogenesis GO:0022612 31 13 0,000 0,05350252 0,09020473 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05350252 0,09014252 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05350252 0,0900804 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05350252 0,09001836 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05350252 0,0899564 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05350252 0,08989454 ! spleen development GO:0048536 24 13 0,000 0,05350252 0,08983275 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05350252 0,08977105 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05350252 0,08970944 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05350252 0,08964791 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05350252 0,08958647 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05350252 0,08952511 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05350252 0,08946383 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05350252 0,08940264 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05350252 0,08934153 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05350252 0,0892805 ! insulin secretion GO:0030073 24 13 0,000 0,05350252 0,08921956 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05350252 0,0891587 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05350252 0,08909792 ! acrosome reaction GO:0007340 19 13 0,000 0,05350252 0,08903723 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05350252 0,08897662 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05350252 0,08891609 ! regulation of DNA binding GO:0051101 167 89 1,000 0,05458478 0,09065303 ! protein localization in nucleus GO:0034504 192 89 1,000 0,05458478 0,09059144 ! regulation of neurological system process GO:0031644 175 89 1,000 0,05458478 0,09052994 ! response to inorganic substance GO:0010035 173 90 1,000 0,0556749 0,09227529 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,0556749 0,09221273 ! response to unfolded protein GO:0006986 139 90 1,000 0,0556749 0,09215026 ! gland development GO:0048732 220 91 1,000 0,05677267 0,09390361 ! rRNA transcription GO:0009303 28 14 0,000 0,05749832 0,0950395 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05749832 0,09497524 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05749832 0,09491107 ! water transport GO:0006833 21 14 0,000 0,05749832 0,09484698 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05749832 0,09478299 ! non-recombinational repair GO:0000726 29 14 0,000 0,05749832 0,09471907 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05749832 0,09465525 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05749832 0,0945915 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,05749832 0,09452785 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05749832 0,09446428 ! lipid localization GO:0010876 32 14 0,000 0,05749832 0,0944008 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05749832 0,0943374 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05749832 0,09427408 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05749832 0,09421085 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05749832 0,09414771 ! arginine metabolic process GO:0006525 21 14 0,000 0,05749832 0,09408465 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05749832 0,09402168 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05749832 0,09395879 ! regulation of heart rate GO:0002027 25 14 0,000 0,05749832 0,09389598 ! fear response GO:0042596 34 14 0,000 0,05749832 0,09383326 ! organic alcohol transport GO:0015850 29 14 0,000 0,05749832 0,09377062 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05749832 0,09370806 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,05749832 0,09364559 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05749832 0,0935832 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05749832 0,0935209 ! bone mineralization GO:0030282 18 14 0,000 0,05749832 0,09345867 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05749832 0,09339653 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05749832 0,09333447 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05749832 0,0932725 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05749832 0,09321061 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05749832 0,0931488 ! regulation of cellular pH GO:0030641 27 14 0,000 0,05749832 0,09308707 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05749832 0,09302542 ! ribosome assembly GO:0042255 18 14 0,000 0,05749832 0,09296385 ! cerebellum development GO:0021549 23 14 0,000 0,05749832 0,09290237 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05749832 0,09284097 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05749832 0,09277965 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05749832 0,09271841 ! response to gamma radiation GO:0010332 30 14 0,000 0,05749832 0,09265725 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05749832 0,09259617 ! NADP metabolic process GO:0006739 24 14 0,000 0,05749832 0,09253517 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05749832 0,09247425 ! oxygen transport GO:0015671 22 14 0,000 0,05749832 0,09241341 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05749832 0,09235265 ! male genitalia development GO:0030539 26 14 0,000 0,05749832 0,09229197 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05749832 0,09223138 ! regulation of axon extension GO:0030516 43 14 0,000 0,05749832 0,09217086 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,05749832 0,09211042 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05749832 0,09205006 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05749832 0,09198977 ! vitamin metabolic process GO:0006766 153 93 1,000 0,05899082 0,09431583 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,06011104 0,096044 ! sterol metabolic process GO:0016125 166 94 1,000 0,06011104 0,09598122 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06147735 0,09809874 ! lactation GO:0007595 30 15 0,000 0,06147735 0,09803471 ! reproductive cellular process GO:0048610 22 15 0,000 0,06147735 0,09797076 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06147735 0,09790689 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06147735 0,09784311 ! superoxide anion generation GO:0042554 22 15 0,000 0,06147735 0,09777941 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06147735 0,09771579 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,06147735 0,09765226 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06147735 0,09758881 ! copper ion transport GO:0006825 22 15 0,000 0,06147735 0,09752544 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06147735 0,09746215 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06147735 0,09739895 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06147735 0,09733582 ! sulfate transport GO:0008272 27 15 0,000 0,06147735 0,09727278 ! response to cAMP GO:0051591 25 15 0,000 0,06147735 0,09720982 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06147735 0,09714694 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06147735 0,09708415 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,06147735 0,09702143 ! response to hexose stimulus GO:0009746 25 15 0,000 0,06147735 0,0969588 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06147735 0,09689624 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,06147735 0,09683377 ! vesicle coating GO:0006901 38 15 0,000 0,06147735 0,09677138 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,06147735 0,09670906 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,06147735 0,09664683 ! regulation of exocytosis GO:0017157 26 15 0,000 0,06147735 0,09658468 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06147735 0,09652261 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,06147735 0,09646061 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06147735 0,0963987 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06147735 0,09633687 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06147735 0,09627511 ! regulation of vasodilation GO:0042312 27 15 0,000 0,06147735 0,09621344 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,06147735 0,09615184 ! histone deacetylation GO:0016575 24 15 0,000 0,06147735 0,09609032 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06147735 0,09602889 ! water homeostasis GO:0030104 28 15 0,000 0,06147735 0,09596753 ! cofactor transport GO:0051181 30 15 0,000 0,06147735 0,09590624 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06147735 0,09584504 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06147735 0,09578391 ! intestinal absorption GO:0050892 31 15 0,000 0,06147735 0,09572287 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06147735 0,0956619 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06147735 0,095601 ! cell killing GO:0001906 32 15 0,000 0,06147735 0,09554019 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,06147735 0,09547945 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,06147735 0,09541879 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06147735 0,09535821 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06147735 0,0952977 ! actin filament polymerization GO:0030041 27 15 0,000 0,06147735 0,09523727 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06147735 0,09517692 ! response to protein stimulus GO:0051789 158 96 1,000 0,06237335 0,09650291 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,06351528 0,09820748 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,06351528 0,09814537 ! regulation of protein localization GO:0032880 188 97 1,000 0,06351528 0,09808333 ! forebrain development GO:0030900 210 98 1,000 0,06466428 0,0997946 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06543971 0,10092753 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06543971 0,10086385 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06543971 0,10080025 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06543971 0,10073674 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06543971 0,1006733 ! bone remodeling GO:0046849 28 16 0,000 0,06543971 0,10060994 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06543971 0,10054667 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06543971 0,10048347 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06543971 0,10042035 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06543971 0,10035731 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06543971 0,10029436 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06543971 0,10023147 ! startle response GO:0001964 28 16 0,000 0,06543971 0,10016867 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06543971 0,10010595 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06543971 0,10004331 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06543971 0,09998074 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06543971 0,09991825 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06543971 0,09985584 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06543971 0,09979351 ! pituitary gland development GO:0021983 30 16 0,000 0,06543971 0,09973126 ! response to osmotic stress GO:0006970 27 16 0,000 0,06543971 0,09966908 ! lysosomal transport GO:0007041 31 16 0,000 0,06543971 0,09960698 ! fructose metabolic process GO:0006000 25 16 0,000 0,06543971 0,09954496 ! L-amino acid transport GO:0015807 33 16 0,000 0,06543971 0,09948301 ! stem cell development GO:0048864 46 16 0,000 0,06543971 0,09942115 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06543971 0,09935935 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06543971 0,09929764 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06543971 0,099236 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06543971 0,09917444 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06543971 0,09911296 ! axon cargo transport GO:0008088 46 16 0,000 0,06543971 0,09905155 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06543971 0,09899022 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06543971 0,09892896 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,06543971 0,09886778 ! DNA replication initiation GO:0006270 28 16 0,000 0,06543971 0,09880668 ! neuron recognition GO:0008038 40 16 0,000 0,06543971 0,09874565 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06543971 0,09868469 ! tissue regeneration GO:0042246 27 16 0,000 0,06543971 0,09862381 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06543971 0,09856301 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06543971 0,09850228 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,06543971 0,09844163 ! biomineral formation GO:0031214 22 16 0,000 0,06543971 0,09838105 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06543971 0,09832054 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06543971 0,09826011 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06543971 0,09819976 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06543971 0,09813947 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06543971 0,09807927 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06543971 0,09801913 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06543971 0,09795907 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,06543971 0,09789908 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06543971 0,09783917 ! peptide hormone processing GO:0016486 27 16 0,000 0,06543971 0,09777933 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,06698322 0,10002445 GO:0060538|skeletal muscle organ development, ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06938544 0,10354834 ! metencephalon development GO:0022037 32 17 0,000 0,06938544 0,10348512 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,06938544 0,10342198 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,06938544 0,10335892 ! signal complex assembly GO:0007172 47 17 0,000 0,06938544 0,10329594 ! filopodium assembly GO:0046847 42 17 0,000 0,06938544 0,10323303 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06938544 0,1031702 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06938544 0,10310744 ! glial cell development GO:0021782 28 17 0,000 0,06938544 0,10304476 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06938544 0,10298216 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06938544 0,10291963 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06938544 0,10285718 ! myoblast differentiation GO:0045445 50 17 0,000 0,06938544 0,1027948 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,06938544 0,1027325 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,06938544 0,10267028 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,06938544 0,10260813 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,06938544 0,10254606 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06938544 0,10248406 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06938544 0,10242213 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,06938544 0,10236028 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,06938544 0,10229851 ! membrane budding GO:0006900 42 17 0,000 0,06938544 0,10223681 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06938544 0,10217518 ! regulation of protein binding GO:0043393 33 17 0,000 0,06938544 0,10211363 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06938544 0,10205216 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06938544 0,10199075 ! genitalia development GO:0048806 32 17 0,000 0,06938544 0,10192942 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06938544 0,10186817 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,06938544 0,10180699 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06938544 0,10174588 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06938544 0,10168484 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,06938544 0,10162388 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06938544 0,10156299 ! steroid catabolic process GO:0006706 34 17 0,000 0,06938544 0,10150217 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06938544 0,10144143 ! gas transport GO:0015669 26 17 0,000 0,06938544 0,10138076 ! organic cation transport GO:0015695 32 17 0,000 0,06938544 0,10132016 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,06938544 0,10125964 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06938544 0,10119918 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06938544 0,1011388 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07331463 0,1068024 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07331463 0,10673876 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07331463 0,10667518 ! limbic system development GO:0021761 40 18 0,000 0,07331463 0,10661169 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07331463 0,10654826 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07331463 0,10648492 ! adult walking behavior GO:0007628 36 18 0,000 0,07331463 0,10642165 ! patterning of blood vessels GO:0001569 43 18 0,000 0,07331463 0,10635845 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07331463 0,10629533 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,07331463 0,10623228 ! centrosome cycle GO:0007098 26 18 0,000 0,07331463 0,10616931 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07331463 0,10610642 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07331463 0,10604359 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07331463 0,10598085 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,07331463 0,10591817 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,07331463 0,10585557 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07331463 0,10579305 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07331463 0,1057306 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07331463 0,10566822 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07331463 0,10560591 ! neural crest cell migration GO:0001755 41 18 0,000 0,07331463 0,10554368 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07331463 0,10548153 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,07331463 0,10541944 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07331463 0,10535743 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,07331463 0,10529549 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,07331463 0,10523363 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,07331463 0,10517183 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07331463 0,10511011 ! nerve development GO:0021675 34 18 0,000 0,07331463 0,10504846 ! defense response to virus GO:0051607 43 18 0,000 0,07331463 0,10498689 ! microspike assembly GO:0030035 46 18 0,000 0,07331463 0,10492538 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07331463 0,10486395 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,07331463 0,10480259 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07722733 0,11033121 ! positive regulation of translation GO:0045727 31 19 0,000 0,07722733 0,11026673 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07722733 0,11020232 ! neuron maturation GO:0042551 46 19 0,000 0,07722733 0,11013799 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07722733 0,11007373 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,07722733 0,11000955 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07722733 0,10994544 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07722733 0,10988141 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,07722733 0,10981745 ! inositol metabolic process GO:0006020 33 19 0,000 0,07722733 0,10975356 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07722733 0,10968975 ! memory GO:0007613 34 19 0,000 0,07722733 0,10962602 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,07722733 0,10956235 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07722733 0,10949877 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07722733 0,10943525 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07722733 0,10937181 ! cerebral cortex development GO:0021987 40 19 0,000 0,07722733 0,10930844 ! heme metabolic process GO:0042168 40 19 0,000 0,07722733 0,10924515 ! neuromuscular junction development GO:0007528 43 19 0,000 0,07722733 0,10918193 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07722733 0,10911878 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,07722733 0,10905571 ! response to fungus GO:0009620 26 19 0,000 0,07722733 0,10899271 ! peptide cross-linking GO:0018149 39 19 0,000 0,07722733 0,10892978 ! protein export from nucleus GO:0006611 40 19 0,000 0,07722733 0,10886692 ! heart process GO:0003015 32 19 0,000 0,07722733 0,10880414 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07722733 0,10874143 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07722733 0,10867879 ! visual learning GO:0008542 38 19 0,000 0,07722733 0,10861622 ! cellular pigmentation GO:0033059 37 19 0,000 0,07722733 0,10855372 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07722733 0,1084913 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07722733 0,10842895 ! vitamin transport GO:0051180 31 19 0,000 0,07722733 0,10836667 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07722733 0,10830446 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07722733 0,10824233 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07722733 0,10818026 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,07722733 0,10811827 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,07722733 0,10805634 ! cilium assembly GO:0042384 38 19 0,000 0,07722733 0,10799449 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07722733 0,10793271 ! protein secretion GO:0009306 45 20 0,000 0,08112363 0,11331334 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08112363 0,11324858 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,08112363 0,11318391 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08112363 0,11311931 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,08112363 0,11305478 ! skin development GO:0043588 42 20 0,000 0,08112363 0,11299032 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08112363 0,11292594 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08112363 0,11286163 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08112363 0,1127974 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08112363 0,11273323 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,08112363 0,11266914 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,08112363 0,11260513 ! bile acid metabolic process GO:0008206 34 20 0,000 0,08112363 0,11254118 ! response to alkaloid GO:0043279 38 20 0,000 0,08112363 0,11247731 ! retinoid metabolic process GO:0001523 34 20 0,000 0,08112363 0,11241351 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,08112363 0,11234979 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,08112363 0,11228613 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08112363 0,11222255 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08112363 0,11215904 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 47 20 0,000 0,08112363 0,1120956 ! body fluid secretion GO:0007589 33 20 0,000 0,08112363 0,11203223 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08112363 0,11196894 ! peptide secretion GO:0002790 38 20 0,000 0,08112363 0,11190572 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08112363 0,11184256 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,08112363 0,11177948 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,08112363 0,11171647 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08112363 0,11165353 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08112363 0,11159067 ! cell-cell junction organization GO:0045216 43 20 0,000 0,08112363 0,11152787 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,08112363 0,11146514 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08112363 0,11140249 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,08112363 0,1113399 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08112363 0,11127739 ! regulation of glucose import GO:0046324 30 20 0,000 0,08112363 0,11121494 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,08112363 0,11115256 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,08112363 0,11109026 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08112363 0,11102802 ! negative regulation of translation GO:0017148 32 20 0,000 0,08112363 0,11096586 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,08112363 0,11090376 ! regulation of cell killing GO:0031341 46 21 0,000 0,08500358 0,11614304 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08500358 0,11607812 ! hormone secretion GO:0046879 39 21 0,000 0,08500358 0,11601327 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08500358 0,11594849 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08500358 0,11588379 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08500358 0,11581916 ! ovarian follicle development GO:0001541 39 21 0,000 0,08500358 0,1157546 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08500358 0,11569011 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,08500358 0,1156257 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08500358 0,11556135 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,08500358 0,11549708 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08500358 0,11543288 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08500358 0,11536875 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08500358 0,11530469 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08500358 0,1152407 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08500358 0,11517679 ! sensory perception of pain GO:0019233 33 21 0,000 0,08500358 0,11511294 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08500358 0,11504917 ! diencephalon development GO:0021536 36 21 0,000 0,08500358 0,11498546 ! collagen fibril organization GO:0030199 62 21 0,000 0,08500358 0,11492183 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,08500358 0,11485827 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08500358 0,11479478 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08500358 0,11473135 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08500358 0,114668 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08500358 0,11460472 ! collagen catabolic process GO:0030574 29 21 0,000 0,08500358 0,11454151 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08500358 0,11447836 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08500358 0,11441529 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08500358 0,11435228 ! actin filament-based movement GO:0030048 47 21 0,000 0,08500358 0,11428935 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,08500358 0,11422648 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,08886726 0,11935279 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,08886726 0,11928721 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,08886726 0,1192217 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,08886726 0,11915627 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,08886726 0,1190909 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,08886726 0,11902561 ! microtubule-based transport GO:0010970 59 22 0,000 0,08886726 0,11896039 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,08886726 0,11889524 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,08886726 0,11883017 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,08886726 0,11876516 ! cellular response to starvation GO:0009267 37 22 0,000 0,08886726 0,11870023 ! vacuolar transport GO:0007034 41 22 0,000 0,08886726 0,11863536 ! central nervous system neuron development GO:0021954 47 22 0,000 0,08886726 0,11857057 ! fucose metabolic process GO:0006004 44 22 0,000 0,08886726 0,11850585 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,08886726 0,1184412 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,08886726 0,11837662 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,08886726 0,11831211 ! ureteric bud development GO:0001657 50 22 0,000 0,08886726 0,11824767 ! cell aging GO:0007569 48 22 0,000 0,08886726 0,1181833 ! stem cell differentiation GO:0048863 57 22 0,000 0,08886726 0,118119 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,08886726 0,11805477 ! cytolysis GO:0019835 27 22 0,000 0,08886726 0,11799061 ! renal system process GO:0003014 42 22 0,000 0,08886726 0,11792652 ! vasodilation GO:0042311 40 22 0,000 0,08886726 0,1178625 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,08886726 0,11779854 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,08886726 0,11773466 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,08886726 0,11767085 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,08886726 0,11760711 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,08886726 0,11754343 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,08886726 0,11747982 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,08886726 0,11741629 ! sarcomere organization GO:0045214 32 22 0,000 0,08886726 0,11735282 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,08886726 0,11728942 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,08886726 0,11722609 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,08886726 0,11716283 ! gut development GO:0048565 44 22 0,000 0,08886726 0,11709963 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,08886726 0,1170365 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,08886726 0,11697345 ! protein stabilization GO:0050821 41 22 0,000 0,08886726 0,11691046 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,09271473 0,1219064 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,09271473 0,12184082 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,09271473 0,12177532 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,09271473 0,12170988 ! gluconeogenesis GO:0006094 38 23 0,000 0,09271473 0,12164452 ! glycerol metabolic process GO:0006071 40 23 0,000 0,09271473 0,12157922 ! viral genome replication GO:0019079 44 23 0,000 0,09271473 0,121514 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,09271473 0,12144884 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,09271473 0,12138376 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,09271473 0,12131874 ! regeneration GO:0031099 42 23 0,000 0,09271473 0,1212538 ! axis specification GO:0009798 43 23 0,000 0,09271473 0,12118892 ! visual behavior GO:0007632 46 23 0,000 0,09271473 0,12112411 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,09271473 0,12105938 ! response to ethanol GO:0045471 47 23 0,000 0,09271473 0,12099471 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,09271473 0,12093011 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,09271473 0,12086558 ! peroxisome organization GO:0007031 43 23 0,000 0,09271473 0,12080112 ! lysosome organization GO:0007040 47 23 0,000 0,09271473 0,12073672 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,09271473 0,1206724 ! vesicle targeting GO:0006903 49 23 0,000 0,09271473 0,12060814 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,09271473 0,12054395 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,09271473 0,12047984 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,09271473 0,12041578 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,09271473 0,1203518 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,09271473 0,12028789 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,09271473 0,12022404 ! hormone transport GO:0009914 41 23 0,000 0,09271473 0,12016026 ! cell-cell recognition GO:0009988 28 23 0,000 0,09271473 0,12009655 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,09271473 0,1200329 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,09271473 0,11996933 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,09271473 0,11990582 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,09654607 0,12479473 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,09654607 0,12472874 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,09654607 0,12466281 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,09654607 0,12459696 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,09654607 0,12453117 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,09654607 0,12446546 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,09654607 0,12439981 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,09654607 0,12433423 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,09654607 0,12426872 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,09654607 0,12420329 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,09654607 0,12413791 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,09654607 0,12407261 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,09654607 0,12400738 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,09654607 0,12394222 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,09654607 0,12387712 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,09654607 0,12381209 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,09654607 0,12374713 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,09654607 0,12368224 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,09654607 0,12361742 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,09654607 0,12355267 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,09654607 0,12348798 ! membrane depolarization GO:0051899 45 24 0,000 0,09654607 0,12342336 ! pallium development GO:0021543 56 24 0,000 0,09654607 0,12335881 ! oogenesis GO:0048477 44 24 0,000 0,09654607 0,12329432 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,09654607 0,12322991 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,09654607 0,12316556 ! platelet activation GO:0030168 41 24 0,000 0,09654607 0,12310127 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,09654607 0,12303706 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,09654607 0,12297291 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,09654607 0,12290883 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,09654607 0,12284481 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,09654607 0,12278086 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,09654607 0,12271698 ! regulation of amine transport GO:0051952 41 24 0,000 0,09654607 0,12265317 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,09654607 0,12258942 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,10036133 0,12736765 ! leukocyte adhesion GO:0007159 55 25 0,000 0,10036133 0,12730152 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,10036133 0,12723546 ! phototransduction GO:0007602 37 25 0,000 0,10036133 0,12716946 ! keratinization GO:0031424 37 25 0,000 0,10036133 0,12710354 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,10036133 0,12703768 ! vacuole organization GO:0007033 49 25 0,000 0,10036133 0,12697189 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,10036133 0,12690617 ! chromosome condensation GO:0030261 48 25 0,000 0,10036133 0,12684052 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,10036133 0,12677493 ! regulation of behavior GO:0050795 48 25 0,000 0,10036133 0,12670942 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,10036133 0,12664397 ! interaction with host GO:0051701 66 25 0,000 0,10036133 0,12657859 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,10036133 0,12651327 ! immunoglobulin production GO:0002377 62 25 0,000 0,10036133 0,12644803 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,10036133 0,12638285 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,10036133 0,12631773 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,10036133 0,12625269 ! liver development GO:0001889 55 25 0,000 0,10036133 0,12618771 ! protein tetramerization GO:0051262 57 25 0,000 0,10036133 0,1261228 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,10416058 0,13082998 ! myelination GO:0042552 50 26 0,000 0,10416058 0,13076275 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,10416058 0,13069559 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,10416058 0,13062849 ! molting cycle process GO:0022404 52 26 0,000 0,10416058 0,13056147 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,10416058 0,13049452 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,10416058 0,13042763 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,10416058 0,13036081 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,10416058 0,13029406 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,10416058 0,13022738 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,10416058 0,13016077 ! digestive system process GO:0022600 49 26 0,000 0,10416058 0,13009423 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,10416058 0,13002775 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,10416058 0,12996134 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,10416058 0,129895 ! osteoblast differentiation GO:0001649 63 26 0,000 0,10416058 0,12982873 ! neural crest cell development GO:0014032 59 26 0,000 0,10416058 0,12976252 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,10416058 0,12969638 ! negative regulation of cell development GO:0010721 83 26 0,000 0,10416058 0,12963031 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,10416058 0,12956431 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,10416058 0,12949837 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,10416058 0,12943251 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,10416058 0,1293667 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,10416058 0,12930097 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,10416058 0,1292353 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,10416058 0,1291697 ! telomere organization GO:0032200 46 26 0,000 0,10416058 0,12910416 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,10416058 0,12903869 ! neural tube closure GO:0001843 58 26 0,000 0,10416058 0,12897329 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,10416058 0,12890796 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,10416058 0,12884269 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,10416058 0,12877748 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1079439 0,13338743 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1079439 0,13332 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1079439 0,13325263 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1079439 0,13318533 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1079439 0,1331181 ! iron ion transport GO:0006826 65 27 0,000 0,1079439 0,13305094 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1079439 0,13298384 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1079439 0,13291681 ! tube lumen formation GO:0035148 59 27 0,000 0,1079439 0,13284985 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1079439 0,13278296 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,1079439 0,13271613 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,1079439 0,13264937 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1079439 0,13258268 ! response to starvation GO:0042594 47 27 0,000 0,1079439 0,13251606 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1079439 0,1324495 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,1079439 0,13238301 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1079439 0,13231659 ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,1079439 0,13225023 ! neuron fate commitment GO:0048663 52 28 0,000 0,11171135 0,13679741 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,11171135 0,13672887 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,11171135 0,1366604 ! vesicle docking GO:0048278 55 28 0,000 0,11171135 0,13659201 ! circadian rhythm GO:0007623 56 28 0,000 0,11171135 0,13652368 ! dendrite development GO:0016358 67 28 0,000 0,11171135 0,13645541 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,11171135 0,13638722 ! sperm motility GO:0030317 37 28 0,000 0,11171135 0,13631909 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,11171135 0,13625104 ! base-excision repair GO:0006284 41 28 0,000 0,11171135 0,13618305 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,11171135 0,13611513 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,11171135 0,13604727 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,11171135 0,13597949 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,11171135 0,13591177 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,11171135 0,13584411 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,11171135 0,13577653 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,11171135 0,13570901 ! glutathione metabolic process GO:0006749 42 28 0,000 0,11171135 0,13564156 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,11171135 0,13557418 ! lipid oxidation GO:0034440 48 28 0,000 0,11171135 0,13550687 GO:0019395|fatty acid oxidation, ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,11546299 0,13998813 ! translational initiation GO:0006413 66 29 0,000 0,11546299 0,13991869 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,11546299 0,13984932 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,11546299 0,13978002 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,11546299 0,13971079 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,11546299 0,13964163 ! primary neural tube formation GO:0014020 61 29 0,000 0,11546299 0,13957253 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,11546299 0,1395035 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,11546299 0,13943455 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,11546299 0,13936566 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,11546299 0,13929683 ! synaptogenesis GO:0007416 46 29 0,000 0,11546299 0,13922808 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,11546299 0,13915939 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,11546299 0,13909077 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,11546299 0,13902222 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,11546299 0,13895374 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,11919889 0,14337907 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,11919889 0,14330851 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,11919889 0,14323802 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,11919889 0,1431676 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,11919889 0,14309725 ! acute-phase response GO:0006953 50 30 0,000 0,11919889 0,14302696 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,11919889 0,14295675 ! myofibril assembly GO:0030239 50 30 0,000 0,11919889 0,1428866 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,11919889 0,14281653 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,11919889 0,14274652 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,11919889 0,14267658 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,11919889 0,14260671 ! phospholipid transport GO:0015914 65 30 0,000 0,11919889 0,1425369 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,11919889 0,14246717 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,11919889 0,1423975 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,11919889 0,14232791 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,11919889 0,14225838 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,11919889 0,14218891 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,11919889 0,14211952 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,12291912 0,14648362 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,12291912 0,14641219 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,12291912 0,14634084 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,12291912 0,14626956 ! cell junction assembly GO:0034329 85 31 0,000 0,12291912 0,14619835 ! regulation of innate immune response GO:0045088 57 31 0,000 0,12291912 0,14612721 ! ovulation cycle process GO:0022602 55 31 0,000 0,12291912 0,14605613 ! peptide transport GO:0015833 60 31 0,000 0,12291912 0,14598513 ! iron ion homeostasis GO:0055072 60 31 0,000 0,12291912 0,14591419 ! detection of light stimulus GO:0009583 44 31 0,000 0,12291912 0,14584333 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,12291912 0,14577253 ! ensheathment of neurons GO:0007272 64 31 0,000 0,12291912 0,1457018 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,12291912 0,14563114 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,12291912 0,14556055 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,12291912 0,14549002 ! eye morphogenesis GO:0048592 65 31 0,000 0,12291912 0,14541957 ! response to heat GO:0009408 54 31 0,000 0,12291912 0,14534918 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,12291912 0,14527886 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,12662374 0,14958501 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,12662374 0,14951271 ! collagen metabolic process GO:0032963 49 32 0,000 0,12662374 0,14944048 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,12662374 0,14936832 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,12662374 0,14929623 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,12662374 0,14922421 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,12662374 0,14915226 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,12662374 0,14908038 ! muscle cell development GO:0055001 52 32 0,000 0,12662374 0,14900857 ! mesoderm formation GO:0001707 73 32 0,000 0,12662374 0,14893683 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,12662374 0,14886516 ! ovulation cycle GO:0042698 57 32 0,000 0,12662374 0,14879355 ! peripheral nervous system development GO:0007422 68 32 0,000 0,12662374 0,14872202 ! BMP signaling pathway GO:0030509 71 32 0,000 0,12662374 0,14865055 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,12662374 0,14857915 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,12662374 0,14850782 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,12662374 0,14843656 ! regulation of pH GO:0006885 56 33 0,000 0,13031281 0,15268787 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,13031281 0,15261467 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,13031281 0,15254155 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,13031281 0,15246849 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,13031281 0,1523955 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,13031281 0,15232259 ! response to ionizing radiation GO:0010212 74 33 0,000 0,13031281 0,15224974 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,13031281 0,15217696 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,13031281 0,15210426 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,13031281 0,15203162 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,13031281 0,15195905 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,13031281 0,15188655 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,13031281 0,15181412 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,13031281 0,15174176 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,13398641 0,15594512 ! post-embryonic development GO:0009791 76 34 0,000 0,13398641 0,15587086 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,13398641 0,15579667 ! cholesterol transport GO:0030301 62 34 0,000 0,13398641 0,15572255 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,13398641 0,1556485 ! spliceosome assembly GO:0000245 75 34 0,000 0,13398641 0,15557453 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,13398641 0,15550062 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,13398641 0,15542678 ! formation of primary germ layer GO:0001704 76 34 0,000 0,13398641 0,15535301 ! cell fate specification GO:0001708 56 34 0,000 0,13398641 0,15527932 ! adult locomotory behavior GO:0008344 62 34 0,000 0,13398641 0,15520569 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,13398641 0,15513213 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,13764459 0,15929216 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,13764459 0,15921673 ! negative regulation of secretion GO:0051048 68 35 0,000 0,13764459 0,15914138 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,13764459 0,1590661 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,13764459 0,15899089 ! membrane docking GO:0022406 69 35 0,000 0,13764459 0,15891576 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,13764459 0,15884069 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,13764459 0,15876569 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,13764459 0,15869077 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,13764459 0,15861592 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,13764459 0,15854113 ! ceramide metabolic process GO:0006672 72 35 0,000 0,13764459 0,15846642 ! telencephalon development GO:0021537 81 35 0,000 0,13764459 0,15839178 ! sterol transport GO:0015918 63 35 0,000 0,13764459 0,1583172 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,13764459 0,1582427 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,13764459 0,15816827 ! vesicle localization GO:0051648 70 35 0,000 0,13764459 0,15809391 ! regulation of muscle development GO:0048634 82 36 0,000 0,14128742 0,16220168 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,14128742 0,16212549 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,14128742 0,16204938 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,14128742 0,16197334 ! positive regulation of cell development GO:0010720 85 36 0,000 0,14128742 0,16189736 ! protein targeting to membrane GO:0006612 75 36 0,000 0,14128742 0,16182146 ! regulation of proteolysis GO:0030162 77 36 0,000 0,14128742 0,16174563 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,14128742 0,16166987 ! aerobic respiration GO:0009060 56 36 0,000 0,14128742 0,16159418 ! cytokine production GO:0001816 68 36 0,000 0,14128742 0,16151857 ! embryonic organ development GO:0048568 67 36 0,000 0,14128742 0,16144302 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,14128742 0,16136754 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,14128742 0,16129214 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,14491497 0,16535604 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,14491497 0,16527884 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,14491497 0,16520171 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,14491497 0,16512466 ! odontogenesis GO:0042476 74 37 0,000 0,14491497 0,16504768 ! actomyosin structure organization GO:0031032 68 37 0,000 0,14491497 0,16497077 ! cell junction organization GO:0034330 96 37 0,000 0,14491497 0,16489393 ! tissue remodeling GO:0048771 78 37 0,000 0,14491497 0,16481717 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,14491497 0,16474047 ! female gonad development GO:0008585 71 37 0,000 0,14491497 0,16466385 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,14491497 0,1645873 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,14491497 0,16451081 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,14491497 0,1644344 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,14852729 0,16845505 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,14852729 0,16837688 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,14852729 0,16829878 ! organic anion transport GO:0015711 82 38 0,000 0,14852729 0,16822076 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,14852729 0,16814281 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,14852729 0,16806493 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,14852729 0,16798712 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,14852729 0,16790938 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,14852729 0,16783172 ! regulation of protein stability GO:0031647 77 38 0,000 0,14852729 0,16775413 ! spermatid development GO:0007286 69 38 0,000 0,14852729 0,16767661 ! pigment metabolic process GO:0042440 87 38 0,000 0,14852729 0,16759916 ! neural tube formation GO:0001841 79 38 0,000 0,14852729 0,16752178 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,15212446 0,17149979 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,15212446 0,17142069 ! negative regulation of binding GO:0051100 71 39 0,000 0,15212446 0,17134165 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,15212446 0,1712627 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,15212446 0,17118381 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,15212446 0,17110499 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,15212446 0,17102625 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,15212446 0,17094758 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,15570653 0,17489243 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,15570653 0,17481206 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,15570653 0,17473176 ! learning GO:0007612 82 40 0,000 0,15570653 0,17465153 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,15570653 0,17457138 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,15570653 0,1744913 ! mismatch repair GO:0006298 58 40 0,000 0,15570653 0,1744113 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,15570653 0,17433137 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,15570653 0,17425151 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,15570653 0,17417172 ! RNA export from nucleus GO:0006405 61 41 0,000 0,15927356 0,17808023 ! mRNA catabolic process GO:0006402 79 41 0,000 0,15927356 0,17799877 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,15927356 0,17791738 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,15927356 0,17783606 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,15927356 0,17775482 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,15927356 0,17767366 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,15927356 0,17759256 ! feeding behavior GO:0007631 69 41 0,000 0,15927356 0,17751155 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,15927356 0,1774306 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,15927356 0,17734973 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,15927356 0,17726893 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,15927356 0,17718821 ! spermatid differentiation GO:0048515 73 41 0,000 0,15927356 0,17710756 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,15927356 0,17702698 ! RNA modification GO:0009451 64 41 0,000 0,15927356 0,17694648 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,16282563 0,18081046 ! ear morphogenesis GO:0042471 64 42 0,000 0,16282563 0,18072831 ! organic ether metabolic process GO:0018904 59 42 0,000 0,16282563 0,18064623 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,16282563 0,18056423 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,16282563 0,18048231 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,16282563 0,18040046 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,16282563 0,18031868 ! regulation of protein secretion GO:0050708 77 42 0,000 0,16282563 0,18023697 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,16282563 0,18015535 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,16282563 0,18007379 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,16636278 0,18390239 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,16636278 0,18381921 ! regulation of tube size GO:0035150 76 43 0,000 0,16636278 0,18373611 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,16636278 0,18365309 ! glucose transport GO:0015758 66 43 0,000 0,16636278 0,18357013 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,16636278 0,18348726 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,16636278 0,18340446 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,16636278 0,18332173 ! ion transmembrane transport GO:0034220 79 43 0,000 0,16636278 0,18323908 ! neuron migration GO:0001764 85 43 0,000 0,16636278 0,1831565 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,16988509 0,18695013 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,16988509 0,18686595 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,16988509 0,18678186 ! hexose transport GO:0008645 68 44 0,000 0,16988509 0,18669783 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,16988509 0,18661389 ! striated muscle contraction GO:0006941 85 44 0,000 0,16988509 0,18653002 ! phagocytosis GO:0006909 105 44 0,000 0,16988509 0,18644622 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,16988509 0,1863625 ! double-strand break repair GO:0006302 85 44 0,000 0,16988509 0,18627885 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,17339262 0,19003956 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,17339262 0,18995434 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,17339262 0,1898692 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,17339262 0,18978413 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,17339262 0,18969914 ! female gamete generation GO:0007292 71 45 0,000 0,17339262 0,18961422 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,17339262 0,18952939 ! polyol metabolic process GO:0019751 77 45 0,000 0,17339262 0,18944462 ! maintenance of location in cell GO:0051651 101 45 0,000 0,17339262 0,18935994 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,17688543 0,19308807 ! glycolysis GO:0006096 71 46 0,000 0,17688543 0,19300183 ! leukocyte migration GO:0050900 75 46 0,000 0,17688543 0,19291567 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,17688543 0,19282959 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,17688543 0,19274358 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,17688543 0,19265765 ! neural tube development GO:0021915 91 47 0,000 0,18036357 0,19635838 ! positive regulation of defense response GO:0031349 88 48 0,000 0,18382712 0,20003993 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,18382712 0,19995087 ! mitochondrial transport GO:0006839 94 48 0,000 0,18382712 0,19986188 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,18382712 0,19977298 ! cellular component disassembly GO:0022411 89 48 0,000 0,18382712 0,19968415 ! endosome transport GO:0016197 127 48 0,000 0,18382712 0,1995954 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,18382712 0,19950673 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,18382712 0,19941814 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,18382712 0,19932963 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,18382712 0,19924119 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,18382712 0,19915284 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,18727612 0,20279946 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,18727612 0,2027096 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,18727612 0,20261983 ! protein homooligomerization GO:0051260 84 49 0,000 0,18727612 0,20253013 ! regulation of action potential GO:0001508 102 50 0,000 0,19071065 0,20615315 ! regulation of ion transport GO:0043269 86 50 0,000 0,19071065 0,20606197 ! endocrine system development GO:0035270 109 50 0,000 0,19071065 0,20597088 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,19071065 0,20587986 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,19071065 0,20578892 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,19071065 0,20569807 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,19071065 0,20560729 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,19413076 0,20920223 ! peptide metabolic process GO:0006518 80 51 0,000 0,19413076 0,20910999 ! response to temperature stimulus GO:0009266 84 51 0,000 0,19413076 0,20901783 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,19413076 0,20892575 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,19413076 0,20883375 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,19753652 0,21240392 ! Notch signaling pathway GO:0007219 111 52 0,000 0,19753652 0,21231047 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,19753652 0,21221711 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,19753652 0,21212383 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,19753652 0,21203063 ! excretion GO:0007588 87 52 0,000 0,19753652 0,21193751 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,19753652 0,21184447 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,19753652 0,21175152 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,19753652 0,21165864 ! amino acid activation GO:0043038 98 52 0,000 0,19753652 0,21156585 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,20092797 0,21510387 ! positive regulation of growth GO:0045927 96 53 0,000 0,20092797 0,21500965 ! inner ear development GO:0048839 89 53 0,000 0,20092797 0,21491551 ! chromatin remodeling GO:0006338 122 53 0,000 0,20092797 0,21482146 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,20092797 0,21472749 ! vesicle organization GO:0016050 127 53 0,000 0,20092797 0,2146336 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,20092797 0,21453979 ! cartilage development GO:0051216 99 53 0,000 0,20092797 0,21444606 ! synapse organization GO:0050808 102 53 0,000 0,20092797 0,21435242 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,20430519 0,21786014 ! regulation of translational initiation GO:0006446 87 54 0,000 0,20430519 0,21776508 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,20430519 0,21767012 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,20430519 0,21757523 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,20430519 0,21748042 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,20430519 0,2173857 ! membrane fusion GO:0006944 122 54 0,000 0,20430519 0,21729106 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,20430519 0,21719651 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,20430519 0,21710203 ! regulation of cell shape GO:0008360 142 54 0,000 0,20430519 0,21700764 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,20430519 0,21691333 ! RNA catabolic process GO:0006401 103 55 0,000 0,20766823 0,22038813 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,20766823 0,22029243 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,20766823 0,22019682 ! cell recognition GO:0008037 98 55 0,000 0,20766823 0,22010129 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,20766823 0,22000584 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,20766823 0,21991048 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,21101714 0,22336 ! glucose catabolic process GO:0006007 88 56 0,000 0,21101714 0,22326327 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,21101714 0,22316662 ! chloride transport GO:0006821 102 57 0,000 0,214352 0,22659539 ! muscle fiber development GO:0048747 131 57 0,000 0,214352 0,22649738 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,214352 0,22639946 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,21767286 0,2298076 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,21767286 0,22970833 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,21767286 0,22960915 ! gastrulation GO:0007369 122 58 0,000 0,21767286 0,22951005 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,21767286 0,22941104 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,21767286 0,22931211 ! maintenance of location GO:0051235 124 58 0,000 0,21767286 0,22921327 ! nuclear export GO:0051168 110 59 0,000 0,22097977 0,23259525 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,2242728 0,23595971 ! regulation of endocytosis GO:0030100 104 60 0,000 0,2242728 0,23585813 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,2242728 0,23575664 ! adult behavior GO:0030534 104 60 0,000 0,2242728 0,23565524 ! positive regulation of secretion GO:0051047 110 61 0,000 0,22755199 0,23899807 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,22755199 0,23889537 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,22755199 0,23879275 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,22755199 0,23869022 ! proton transport GO:0015992 117 61 0,000 0,22755199 0,23858778 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,22755199 0,23848542 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,23081742 0,24180402 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,23081742 0,24170037 ! tRNA processing GO:0008033 102 62 0,000 0,23081742 0,24159681 ! mesoderm development GO:0007498 128 63 0,000 0,23406914 0,24489546 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,23406914 0,24479063 ! hydrogen transport GO:0006818 121 64 0,000 0,2373072 0,24807081 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,2373072 0,24796471 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,2373072 0,2478587 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,2373072 0,24775277 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,24053166 0,2510119 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,24053166 0,25090472 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,24053166 0,25079763 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,24053166 0,25069064 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,24053166 0,25058373 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,24053166 0,25047692 ! ear development GO:0043583 114 66 0,000 0,24374258 0,25371245 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,24374258 0,2536044 ! activation of MAPK activity GO:0000187 124 67 0,000 0,24694002 0,25682182 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,24694002 0,25671254 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,24694002 0,25660334 ! secondary metabolic process GO:0019748 125 67 0,000 0,24694002 0,25649424 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,25012402 0,25969103 ! hexose catabolic process GO:0019320 113 68 0,000 0,25012402 0,25958071 ! extracellular matrix organization GO:0030198 146 68 0,000 0,25012402 0,25947048 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,25012402 0,25936035 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,25012402 0,25925031 ! regulation of lipase activity GO:0060191 137 68 0,000 0,25012402 0,25914037 ! adaptive immune response GO:0002250 126 68 0,000 0,25012402 0,25903052 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,25012402 0,25892076 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,25329466 0,26209185 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,25329466 0,26198088 ! single fertilization GO:0007338 83 69 0,000 0,25329466 0,26187002 ! cell redox homeostasis GO:0045454 114 70 0,000 0,25645197 0,26502207 ! activation of immune response GO:0002253 120 70 0,000 0,25645197 0,26491001 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,25645197 0,26479804 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,25959603 0,26793118 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,25959603 0,26781803 ! carbohydrate transport GO:0008643 114 72 0,000 0,26272688 0,27093363 ! actin filament organization GO:0007015 167 72 0,000 0,26272688 0,27081931 ! B cell activation GO:0042113 179 72 0,000 0,26272688 0,27070509 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,26272688 0,27059096 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,26272688 0,27047693 ! humoral immune response GO:0006959 115 73 0,000 0,26584458 0,27357131 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,26584458 0,27345613 ! regulation of immune effector process GO:0002697 156 73 0,000 0,26584458 0,27334103 ! acute inflammatory response GO:0002526 118 74 0,000 0,26894918 0,27641684 ! amino acid transport GO:0006865 148 74 0,000 0,26894918 0,2763006 ! transition metal ion transport GO:0000041 143 75 0,000 0,27204074 0,27935919 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,27204074 0,27924181 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,27204074 0,27912454 ! axon guidance GO:0007411 162 75 0,000 0,27204074 0,27900735 ! rhythmic process GO:0048511 142 75 0,000 0,27204074 0,27889027 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,27511931 0,28192805 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,27511931 0,28180984 ! neurotransmitter transport GO:0006836 142 77 0,000 0,27818495 0,28483061 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,27818495 0,28471128 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,27818495 0,28459206 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,27818495 0,28447293 ! regulation of catabolic process GO:0009894 173 77 0,000 0,27818495 0,2843539 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,28123771 0,28735413 ! fertilization GO:0009566 99 78 0,000 0,28123771 0,287234 ! blood coagulation GO:0007596 151 79 0,000 0,28427764 0,29021742 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,28427764 0,29009619 ! protein oligomerization GO:0051259 149 79 0,000 0,28427764 0,28997507 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,29332103 0,29907483 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,2963102 0,30199659 ! exocytosis GO:0006887 153 83 0,000 0,2963102 0,30187065 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,2963102 0,30174482 ! inorganic anion transport GO:0015698 156 83 0,000 0,2963102 0,30161909 ! digestion GO:0007586 130 84 0,000 0,29928681 0,30452214 ! hemostasis GO:0007599 165 85 0,000 0,30225091 0,30741006 ! negative regulation of transport GO:0051051 164 85 0,000 0,30225091 0,30728213 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,30225091 0,30715431 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,30225091 0,3070266 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,30520255 0,30989602 ! regulation of lyase activity GO:0051339 169 86 0,000 0,30520255 0,30976728 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,30814179 0,3126206 ! mitochondrion organization GO:0007005 159 87 0,000 0,30814179 0,31249083 ! alcohol catabolic process GO:0046164 142 87 0,000 0,30814179 0,31236116 ! nucleosome assembly GO:0006334 126 87 0,000 0,30814179 0,3122316 ! cellular respiration GO:0045333 143 88 0,000 0,31106868 0,31506666 ! amine biosynthetic process GO:0009309 146 88 0,000 0,31106868 0,31493609 ! sensory perception of smell GO:0007608 117 88 0,000 0,31106868 0,31480563 ! chromatin assembly GO:0031497 128 88 0,000 0,31106868 0,31467528 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,31398327 0,31749219 ! tube morphogenesis GO:0035239 194 89 0,000 0,31398327 0,31736083 ! cellular defense response GO:0006968 123 89 0,000 0,31398327 0,31722958 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,31688561 0,32002958 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,31977576 0,32281495 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,31977576 0,32268161 ! defense response to bacterium GO:0042742 112 91 0,000 0,31977576 0,32254838 ! bone development GO:0060348 206 92 0,000 0,32265375 0,32531701 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,32265375 0,32518281 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,32551966 0,32793588 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,32551966 0,32780071 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,32551966 0,32766564 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,32551966 0,32753069 ! female pregnancy GO:0007565 166 94 0,000 0,32837351 0,33026615 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,32837351 0,33013024 ! regulation of membrane potential GO:0042391 179 94 0,000 0,32837351 0,32999444 ! regulation of defense response GO:0031347 171 95 0,000 0,33121537 0,33271347 ! nucleosome organization GO:0034728 143 95 0,000 0,33121537 0,33257672 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,33121537 0,33244008 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,33121537 0,33230355 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,33121537 0,33216714 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,33121537 0,33203084 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,33121537 0,33189465 ! regulation of T cell activation GO:0050863 175 96 0,000 0,33404529 0,33459313 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,33966949 0,34008711 ! mRNA transport GO:0051028 185 100 0,000 0,3452465 0,34552937 ! positive regulation of immune response GO:0050778 175 100 0,000 0,3452465 0,34538788 ! hormone metabolic process GO:0042445 171 100 0,000 0,3452465 0,3452465