pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1169-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 12 6 2,000 1,076E-06 2,588E-03 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,076E-06 1,294E-03 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,877E-06 1,505E-03 ! macrophage differentiation GO:0030225 11 7 2,000 1,877E-06 1,129E-03 ! establishment of nucleus localization GO:0040023 16 8 2,000 2,995E-06 1,441E-03 ! protein sumoylation GO:0016925 15 10 2,000 6,382E-06 2,559E-03 ! nucleus localization GO:0051647 19 11 2,000 8,751E-06 3,008E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,164E-05 3,5E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 2,000 1,915E-05 5,118E-03 ! filopodium assembly GO:0046847 32 16 2,000 2,929E-05 7,047E-03 ! microspike assembly GO:0030035 36 17 2,000 3,547E-05 7,758E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 9,084E-05 0,01821365 ! regulation of homeostatic process GO:0032844 134 62 3,000 9,486E-05 0,01755584 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,173E-04 0,02016236 ! protein maturation by protein folding GO:0022417 13 5 1,000 1,435E-04 0,02301101 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,435E-04 0,02157282 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 1,435E-04 0,02030383 ! sequestering of calcium ion GO:0051208 7 5 1,000 1,435E-04 0,01917584 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,484E-04 0,01878869 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,657E-04 0,01993561 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,843E-04 0,02111819 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 2,147E-04 0,02347517 ! triglyceride catabolic process GO:0019433 10 6 1,000 2,147E-04 0,02245451 ! response to drug GO:0042493 143 82 3,000 2,805E-04 0,02811672 ! prostate gland development GO:0030850 13 7 1,000 2,998E-04 0,02884915 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,998E-04 0,02773956 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,998E-04 0,02671217 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 2,998E-04 0,02575817 GO:0031958|corticosteroid receptor signaling pathway, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,998E-04 0,02486995 ! glycerol ether catabolic process GO:0044269 12 7 1,000 2,998E-04 0,02404095 GO:0046464|acylglycerol catabolic process, ! regulation of meiosis GO:0040020 12 7 1,000 2,998E-04 0,02326544 GO:0051445|regulation of meiotic cell cycle, ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 3,833E-04 0,02882173 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,987E-04 0,02906776 ! neutral lipid catabolic process GO:0046461 13 8 1,000 3,987E-04 0,02821283 ! oligopeptide transport GO:0006857 15 8 1,000 3,987E-04 0,02740675 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 3,987E-04 0,02664545 ! glycerolipid catabolic process GO:0046503 13 8 1,000 3,987E-04 0,0259253 ! ER overload response GO:0006983 12 8 1,000 3,987E-04 0,02524306 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 3,987E-04 0,0245958 ! CTP metabolic process GO:0046036 9 9 1,000 5,113E-04 0,03075559 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! microtubule bundle formation GO:0001578 21 9 1,000 5,113E-04 0,03000546 ! middle ear morphogenesis GO:0042474 14 9 1,000 5,113E-04 0,02929104 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 5,113E-04 0,02860986 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 5,113E-04 0,02795963 ! regulation of telomere maintenance GO:0032204 14 9 1,000 5,113E-04 0,02733831 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 5,586E-04 0,02921481 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 6,375E-04 0,03263704 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 6,375E-04 0,0319571 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 1,000 6,375E-04 0,03130491 ! apical protein localization GO:0045176 15 10 1,000 6,375E-04 0,03067881 ! pigmentation GO:0043473 100 46 2,000 7,304E-04 0,0344588 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 7,773E-04 0,03596418 ! detection of mechanical stimulus GO:0050982 22 11 1,000 7,773E-04 0,03528561 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 7,773E-04 0,03463217 ! DNA methylation GO:0006306 19 11 1,000 7,773E-04 0,0340025 GO:0006305|DNA alkylation, ! sequestering of metal ion GO:0051238 14 11 1,000 7,773E-04 0,03339531 ! positive regulation of cell cycle GO:0045787 89 48 2,000 8,276E-04 0,03493497 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 9,304E-04 0,03859596 ! asymmetric protein localization GO:0008105 20 12 1,000 9,304E-04 0,03794179 ! entry into host cell GO:0030260 32 12 1,000 9,304E-04 0,03730943 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 16 12 1,000 9,304E-04 0,0366978 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 1,000 9,304E-04 0,0361059 ! histone acetylation GO:0016573 26 12 1,000 9,304E-04 0,03553279 ! peptidyl-lysine modification GO:0018205 21 12 1,000 9,304E-04 0,03497759 ! regulation of cell projection organization GO:0031344 121 50 2,000 9,327E-04 0,03452423 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,097E-03 0,03998453 ! aging GO:0007568 103 55 2,000 1,231E-03 0,0442151 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,276E-03 0,0451637 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 1,000 1,276E-03 0,04450915 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,276E-03 0,04387331 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,366E-03 0,04627804 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 1,000 1,469E-03 0,04909416 ! dopamine metabolic process GO:0042417 35 15 1,000 1,469E-03 0,04842164 ! establishment of organelle localization GO:0051656 109 59 2,000 1,509E-03 0,04905986 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,661E-03 0,05329313 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,675E-03 0,05302211 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 1,675E-03 0,05233351 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,675E-03 0,05166257 GO:0031114|regulation of microtubule depolymerization, ! DNA replication initiation GO:0006270 27 16 1,000 1,675E-03 0,05100862 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 1,823E-03 0,05482373 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,893E-03 0,05624189 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 1,000 1,893E-03 0,05555602 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,893E-03 0,05488667 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,893E-03 0,05423325 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,994E-03 0,0564429 ! cell projection assembly GO:0030031 120 66 2,000 2,083E-03 0,05828173 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,125E-03 0,05876181 ! glutamine metabolic process GO:0006541 29 18 1,000 2,125E-03 0,05809407 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,125E-03 0,05744132 ! lipid phosphorylation GO:0046834 35 19 1,000 2,369E-03 0,06332773 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 2,369E-03 0,06263182 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,369E-03 0,06195104 GO:0030968|endoplasmic reticulum unfolded protein response, ! protein export from nucleus GO:0006611 36 19 1,000 2,369E-03 0,0612849 ! cellular pigmentation GO:0033059 36 19 1,000 2,369E-03 0,06063293 ! G1 phase GO:0051318 40 19 1,000 2,369E-03 0,05999469 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 2,369E-03 0,05936975 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,626E-03 0,06512381 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 2,626E-03 0,06445928 ! response to alkaloid GO:0043279 38 20 1,000 2,626E-03 0,06380818 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,626E-03 0,0631701 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,626E-03 0,06254465 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 1,000 2,626E-03 0,06193147 ! negative regulation of translation GO:0017148 29 20 1,000 2,626E-03 0,06133019 ! organelle localization GO:0051640 136 74 2,000 2,887E-03 0,06678037 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 2,895E-03 0,06632937 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 2,895E-03 0,06570362 ! cell aging GO:0007569 44 21 1,000 2,895E-03 0,06508957 ! DNA modification GO:0006304 34 21 1,000 2,895E-03 0,06448689 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,176E-03 0,07010994 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 3,176E-03 0,06947258 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,176E-03 0,0688467 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,176E-03 0,06823199 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 3,176E-03 0,06762817 ! protein stabilization GO:0050821 39 22 1,000 3,176E-03 0,06703494 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,47E-03 0,07259979 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 3,47E-03 0,07197393 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 3,47E-03 0,07135877 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 3,47E-03 0,07075403 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 1,000 3,47E-03 0,07015946 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 3,776E-03 0,07571107 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 3,776E-03 0,07508536 ! interaction with host GO:0051701 62 25 1,000 4,094E-03 0,08074436 ! somitogenesis GO:0001756 43 25 1,000 4,094E-03 0,0800879 ! initiation of viral infection GO:0019059 57 26 1,000 4,424E-03 0,08584835 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 4,424E-03 0,08516157 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 4,424E-03 0,08448568 ! cellular response to oxidative stress GO:0034599 39 26 1,000 4,424E-03 0,08382044 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 4,424E-03 0,08316559 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 4,767E-03 0,08890118 ! protein amino acid acylation GO:0043543 55 27 1,000 4,767E-03 0,08821733 ! fat cell differentiation GO:0045444 50 27 1,000 4,767E-03 0,08754391 ! regulation of chromosome organization GO:0033044 42 27 1,000 4,767E-03 0,0868807 ! glutathione metabolic process GO:0006749 39 27 1,000 4,767E-03 0,08622746 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 4,767E-03 0,08558398 ! dendrite development GO:0016358 59 28 1,000 5,12E-03 0,09125745 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 5,12E-03 0,09058644 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 5,12E-03 0,08992522 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 5,486E-03 0,0956484 ! catechol metabolic process GO:0009712 54 29 1,000 5,486E-03 0,09496029 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! sterol biosynthetic process GO:0016126 52 29 1,000 5,486E-03 0,094282 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 5,486E-03 0,09361333 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 5,817E-03 0,09856163 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 5,817E-03 0,09787238 ! phenol metabolic process GO:0018958 55 30 1,000 5,863E-03 0,09796667 ! leukocyte differentiation GO:0002521 202 96 2,000 5,988E-03 0,09936237 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 6,162E-03 0,10155158 ! peptide transport GO:0015833 55 31 1,000 6,252E-03 0,10233126 ! triglyceride metabolic process GO:0006641 43 31 1,000 6,252E-03 0,10163983 ! iron ion homeostasis GO:0055072 54 31 1,000 6,252E-03 0,10095769 ! interphase GO:0051325 213 98 2,000 6,339E-03 0,10168494 ! response to mechanical stimulus GO:0009612 57 32 1,000 6,652E-03 0,10599829 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 6,652E-03 0,10530094 ! cell cycle arrest GO:0007050 213 100 2,000 6,703E-03 0,10540497 ! positive regulation of endocytosis GO:0045807 50 34 1,000 7,487E-03 0,11697152 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 7,487E-03 0,11621686 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 1,000 7,487E-03 0,11547188 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 7,487E-03 0,1147364 ! neutral lipid metabolic process GO:0006638 50 35 1,000 7,921E-03 0,12062026 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 1,000 7,921E-03 0,11986165 ! glycerol ether metabolic process GO:0006662 53 37 1,000 8,822E-03 0,13266624 ! regulation of protein stability GO:0031647 73 37 1,000 8,822E-03 0,13184222 ! glycogen metabolic process GO:0005977 61 37 1,000 8,822E-03 0,13102838 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 8,822E-03 0,13022453 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 9,289E-03 0,13628279 ! nucleus organization GO:0006997 67 38 1,000 9,289E-03 0,13545683 ! glucan metabolic process GO:0044042 62 38 1,000 9,289E-03 0,13464083 GO:0006073|cellular glucan metabolic process, ! ear morphogenesis GO:0042471 60 39 1,000 9,767E-03 0,14071972 ! organic ether metabolic process GO:0018904 55 39 1,000 9,767E-03 0,1398821 ! segmentation GO:0035282 67 39 1,000 9,767E-03 0,1390544 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,01025596 0,14515196 ! gliogenesis GO:0042063 88 41 1,000 0,01075523 0,151328 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01126507 0,15757994 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01126507 0,15666907 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01126507 0,15576867 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01126507 0,15487857 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,01178537 0,1611114 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01178537 0,16020117 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01178537 0,15930116 ! biopolymer methylation GO:0043414 84 44 1,000 0,01231607 0,16554444 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01285706 0,17185604 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,01285706 0,17090656 ! cell growth GO:0016049 84 45 1,000 0,01285706 0,16996751 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,01340827 0,1762858 ! response to insulin stimulus GO:0032868 95 46 1,000 0,01340827 0,17532772 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01340827 0,17438 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01340827 0,17344248 ! response to calcium ion GO:0051592 81 47 1,000 0,01396961 0,17973738 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01396961 0,17878133 ! methylation GO:0032259 90 47 1,000 0,01396961 0,1778354 ! cellular component disassembly GO:0022411 86 48 1,000 0,014541 0,18413503 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 0,014541 0,18317097 ! activation of caspase activity GO:0006919 84 48 1,000 0,014541 0,18221696 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01512236 0,18852018 ! peptide metabolic process GO:0006518 76 49 1,000 0,01512236 0,18754843 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01512236 0,18658664 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01512236 0,18563467 ! regulation of ossification GO:0030278 117 50 1,000 0,01571359 0,19191324 ! histone modification GO:0016570 91 50 1,000 0,01571359 0,19094398 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01571359 0,18998446 ! positive regulation of binding GO:0051099 78 51 1,000 0,01631463 0,19626499 ! viral infectious cycle GO:0019058 99 51 1,000 0,01631463 0,19528854 ! regulation of cell shape GO:0008360 125 51 1,000 0,01631463 0,19432177 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01692538 0,20060327 ! amino acid activation GO:0043038 92 52 1,000 0,01692538 0,19961992 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! response to UV GO:0009411 104 53 1,000 0,01754577 0,20592738 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01817571 0,21228519 ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,01817571 0,21125965 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01881512 0,21764027 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01881512 0,21659893 ! nuclear export GO:0051168 97 55 1,000 0,01881512 0,21556751 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01894821 0,21606344 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01894821 0,21504427 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01894821 0,21403467 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01894821 0,21303451 ! neuron fate determination GO:0048664 7 5 0,000 0,01894821 0,21204365 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01894821 0,21106197 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01894821 0,21008933 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01894821 0,20912562 ! polyol transport GO:0015791 12 5 0,000 0,01894821 0,20817071 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01894821 0,20722448 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01894821 0,20628681 ! response to superoxide GO:0000303 10 5 0,000 0,01894821 0,20535759 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01894821 0,2044367 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01894821 0,20352404 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01894821 0,20261949 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01894821 0,20172294 ! female meiosis GO:0007143 7 5 0,000 0,01894821 0,20083429 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01894821 0,19995344 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01894821 0,19908028 ! cobalt ion transport GO:0006824 11 5 0,000 0,01894821 0,19821472 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01894821 0,19735664 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01894821 0,19650597 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01894821 0,1956626 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01894821 0,19482643 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01894821 0,19399738 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01894821 0,19317536 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01894821 0,19236027 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01894821 0,19155204 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01894821 0,19075056 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01894821 0,18995577 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01894821 0,18916757 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01894821 0,18838589 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01894821 0,18761064 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01894821 0,18684174 ! negative chemotaxis GO:0050919 14 5 0,000 0,01894821 0,18607912 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01894821 0,1853227 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01894821 0,18457241 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01894821 0,18382817 ! behavioral response to pain GO:0048266 9 5 0,000 0,01894821 0,1830899 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01894821 0,18235754 ! Notch receptor processing GO:0007220 8 5 0,000 0,01894821 0,18163102 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01894821 0,18091026 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01894821 0,1801952 ! micturition GO:0060073 9 5 0,000 0,01894821 0,17948577 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01894821 0,1787819 ! copulation GO:0007620 9 5 0,000 0,01894821 0,17808353 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01894821 0,1773906 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01894821 0,17670304 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01894821 0,17602079 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01894821 0,17534379 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01894821 0,17467197 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01894821 0,17400529 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01894821 0,17334367 ! grooming behavior GO:0007625 6 5 0,000 0,01894821 0,17268706 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01894821 0,17203541 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01894821 0,17138867 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01894821 0,17074676 ! response to protozoan GO:0001562 10 5 0,000 0,01894821 0,17010965 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01894821 0,16947727 ! lymph vessel development GO:0001945 10 5 0,000 0,01894821 0,16884957 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01894821 0,16822651 ! endochondral ossification GO:0001958 16 5 0,000 0,01894821 0,16760803 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01894821 0,16699408 ! parathyroid gland development GO:0060017 13 5 0,000 0,01894821 0,16638462 ! anagen GO:0042640 6 5 0,000 0,01894821 0,16577958 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01894821 0,16517893 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01894821 0,16458262 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01894821 0,16399059 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01894821 0,16340281 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01894821 0,16281923 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01894821 0,1622398 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01894821 0,16166449 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01894821 0,16109323 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01894821 0,160526 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01894821 0,15996275 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01894821 0,15940344 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01894821 0,15884803 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01894821 0,15829648 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01894821 0,15774874 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01894821 0,15720478 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01894821 0,15666455 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01894821 0,15612803 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01894821 0,15559517 ! histidine catabolic process GO:0006548 6 5 0,000 0,01894821 0,15506594 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01894821 0,15454029 ! microvillus organization GO:0032528 7 5 0,000 0,01894821 0,15401819 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01894821 0,15349961 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01894821 0,15298451 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01894821 0,15247286 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01894821 0,15196462 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01894821 0,15145975 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01894821 0,15095823 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01894821 0,15046002 ! polyol catabolic process GO:0046174 7 5 0,000 0,01894821 0,14996508 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01894821 0,14947339 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01894821 0,14898492 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01894821 0,14849963 ! muscle cell migration GO:0014812 8 5 0,000 0,01894821 0,14801748 ! mitochondrial fission GO:0000266 8 5 0,000 0,01894821 0,14753846 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01894821 0,14706253 ! mRNA transcription GO:0009299 9 5 0,000 0,01894821 0,14658966 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01894821 0,14611982 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01894821 0,14565299 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01894821 0,14518912 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01894821 0,14472821 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01894821 0,14427021 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01894821 0,14381509 ! response to food GO:0032094 6 5 0,000 0,01894821 0,14336285 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01894821 0,14291343 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01894821 0,14246683 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01894821 0,14202301 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01894821 0,14158194 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01894821 0,14114361 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01894821 0,14070798 ! forebrain neuron development GO:0021884 13 5 0,000 0,01894821 0,14027503 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01894821 0,13984474 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01894821 0,13941708 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01894821 0,13899203 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01894821 0,13856956 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01894821 0,13814965 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01894821 0,13773228 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01894821 0,13731742 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01894821 0,13690506 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01894821 0,13649516 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01894821 0,13608772 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01894821 0,13568269 ! basic amino acid transport GO:0015802 11 5 0,000 0,01894821 0,13528007 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01894821 0,13487984 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01894821 0,13448196 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01894821 0,13408643 ! depyrimidination GO:0045008 10 5 0,000 0,01894821 0,13369321 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01894821 0,1333023 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01894821 0,13291366 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01894821 0,13252728 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01894821 0,13214314 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01894821 0,13176123 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01894821 0,13138151 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01894821 0,13100398 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01894821 0,13062861 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01894821 0,13025539 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01894821 0,12988429 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01894821 0,1295153 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01894821 0,1291484 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01894821 0,12878357 ! response to arsenic GO:0046685 10 5 0,000 0,01894821 0,1284208 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01894821 0,12806007 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01894821 0,12770136 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01894821 0,12734465 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01894821 0,12698993 ! response to cadmium ion GO:0046686 7 5 0,000 0,01894821 0,12663718 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01894821 0,12628638 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01894821 0,12593753 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01894821 0,12559059 ! decidualization GO:0046697 11 5 0,000 0,01894821 0,12524556 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01894821 0,12490242 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01894821 0,12456116 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01894821 0,12422176 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01894821 0,1238842 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01894821 0,12354847 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01894821 0,12321455 ! neural tube patterning GO:0021532 7 5 0,000 0,01894821 0,12288244 ! embryonic cleavage GO:0040016 6 5 0,000 0,01894821 0,12255211 ! peroxisome fission GO:0016559 5 5 0,000 0,01894821 0,12222355 ! histone demethylation GO:0016577 10 5 0,000 0,01894821 0,12189675 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01894821 0,12157169 ! mitotic recombination GO:0006312 9 5 0,000 0,01894821 0,12124836 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01894821 0,12092675 ! metaphase plate congression GO:0051310 7 5 0,000 0,01894821 0,12060684 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01894821 0,12028861 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01894821 0,11997207 ! enteric nervous system development GO:0048484 8 5 0,000 0,01894821 0,11965718 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01894821 0,11934394 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01894821 0,11903234 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01894821 0,11872236 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01894821 0,11841399 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01894821 0,11810721 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01894821 0,11780203 ! plasminogen activation GO:0031639 5 5 0,000 0,01894821 0,11749841 ! B cell homeostasis GO:0001782 13 5 0,000 0,01894821 0,11719636 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01894821 0,11689586 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01894821 0,11659689 ! metaphase GO:0051323 8 5 0,000 0,01894821 0,11629945 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01894821 0,11600352 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01894821 0,1157091 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01894821 0,11541616 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01894821 0,11512471 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01894821 0,11483472 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01894821 0,11454619 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01894821 0,11425911 ! response to redox state GO:0051775 5 5 0,000 0,01894821 0,11397346 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01894821 0,11368924 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01894821 0,11340643 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01894821 0,11312502 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01894821 0,11284501 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01894821 0,11256638 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01894821 0,11228913 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01894821 0,11201323 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01894821 0,11173869 ! striatum development GO:0021756 9 5 0,000 0,01894821 0,11146549 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01894821 0,11119362 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01894821 0,11092308 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01894821 0,11065385 ! glial cell migration GO:0008347 11 5 0,000 0,01894821 0,11038592 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01894821 0,11011929 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01894821 0,10985394 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01894821 0,10958987 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01894821 0,10932706 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01894821 0,10906551 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01894821 0,10880521 ! neuroprotection GO:0043526 6 5 0,000 0,01894821 0,10854615 ! neural plate development GO:0001840 8 5 0,000 0,01894821 0,10828833 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01894821 0,10803172 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01894821 0,10777632 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01894821 0,10752213 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01894821 0,10726914 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01894821 0,10701734 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01894821 0,10676671 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01894821 0,10651725 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01894821 0,10626896 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01894821 0,10602183 ! spindle assembly GO:0051225 6 5 0,000 0,01894821 0,10577584 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01894821 0,10553098 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01894821 0,10528726 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01894821 0,10504467 ! drug metabolic process GO:0017144 6 5 0,000 0,01894821 0,10480318 ! stem cell division GO:0017145 11 5 0,000 0,01894821 0,10456281 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01894821 0,10432354 ! organ regeneration GO:0031100 7 5 0,000 0,01894821 0,10408535 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01894821 0,10384826 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01894821 0,10361224 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01894821 0,10337729 ! regulation of DNA replication GO:0006275 101 56 1,000 0,01946393 0,10595069 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,02012204 0,10928587 ! lipid modification GO:0030258 97 57 1,000 0,02012204 0,10903973 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02012204 0,10879469 ! maintenance of location GO:0051235 118 57 1,000 0,02012204 0,10855076 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,0207894 0,11189998 ! regulation of endocytosis GO:0030100 91 58 1,000 0,0207894 0,1116502 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02146591 0,11502666 ! DNA catabolic process GO:0006308 86 59 1,000 0,02146591 0,11477104 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,02215149 0,11817403 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02215149 0,11791258 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02269492 0,12053857 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02269492 0,12027306 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02269492 0,12000873 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02269492 0,11974555 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02269492 0,11948353 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02269492 0,11922264 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02269492 0,1189629 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02269492 0,11870429 ! sleep GO:0030431 13 6 0,000 0,02269492 0,11844679 ! response to oxygen radical GO:0000305 11 6 0,000 0,02269492 0,11819041 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02269492 0,11793514 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02269492 0,11768097 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02269492 0,11742789 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02269492 0,1171759 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02269492 0,11692499 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02269492 0,11667515 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02269492 0,11642638 ! forebrain regionalization GO:0021871 8 6 0,000 0,02269492 0,11617866 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02269492 0,115932 ! male meiosis GO:0007140 7 6 0,000 0,02269492 0,11568638 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02269492 0,1154418 ! response to zinc ion GO:0010043 9 6 0,000 0,02269492 0,11519825 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02269492 0,11495573 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02269492 0,11471423 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02269492 0,11447373 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02269492 0,11423425 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02269492 0,11399576 ! malate metabolic process GO:0006108 11 6 0,000 0,02269492 0,11375827 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02269492 0,11352177 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02269492 0,11328625 ! protein refolding GO:0042026 15 6 0,000 0,02269492 0,1130517 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02269492 0,11281812 ! opsonization GO:0008228 8 6 0,000 0,02269492 0,11258551 ! mating behavior GO:0007617 7 6 0,000 0,02269492 0,11235385 ! neuron remodeling GO:0016322 15 6 0,000 0,02269492 0,11212314 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02269492 0,11189338 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02269492 0,11166456 ! equilibrioception GO:0050957 14 6 0,000 0,02269492 0,11143668 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02269492 0,11120972 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02269492 0,11098368 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02269492 0,11075856 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02269492 0,11053435 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02269492 0,11031105 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02269492 0,11008865 ! toxin metabolic process GO:0009404 11 6 0,000 0,02269492 0,10986715 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02269492 0,10964653 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02269492 0,1094268 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02269492 0,10920794 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02269492 0,10898996 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02269492 0,10877285 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02269492 0,1085566 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02269492 0,10834121 ! thymic T cell selection GO:0045061 12 6 0,000 0,02269492 0,10812668 ! protein lipoylation GO:0009249 10 6 0,000 0,02269492 0,10791299 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02269492 0,10770014 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02269492 0,10748813 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02269492 0,10727696 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02269492 0,10706661 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02269492 0,10685709 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02269492 0,10664838 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02269492 0,10644049 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02269492 0,10623341 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02269492 0,10602713 ! hyperosmotic response GO:0006972 9 6 0,000 0,02269492 0,10582165 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02269492 0,10561697 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02269492 0,10541307 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02269492 0,10520996 ! urea metabolic process GO:0019627 7 6 0,000 0,02269492 0,10500764 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02269492 0,10480609 ! neutrophil activation GO:0042119 8 6 0,000 0,02269492 0,10460531 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02269492 0,1044053 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02269492 0,10420605 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02269492 0,10400756 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02269492 0,10380983 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02269492 0,10361285 ! neuron apoptosis GO:0051402 9 6 0,000 0,02269492 0,10341661 ! nucleoside salvage GO:0043174 9 6 0,000 0,02269492 0,10322112 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02269492 0,10302636 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02269492 0,10283234 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02269492 0,10263904 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02269492 0,10244647 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02269492 0,10225463 ! carnitine transport GO:0015879 10 6 0,000 0,02269492 0,1020635 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02269492 0,10187308 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02269492 0,10168337 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02269492 0,10149437 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02269492 0,10130607 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02269492 0,10111847 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02269492 0,10093155 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02269492 0,10074533 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02269492 0,1005598 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02269492 0,10037495 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02269492 0,10019077 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02269492 0,10000727 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02269492 0,09982444 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02269492 0,09964228 ! neural nucleus development GO:0048857 14 6 0,000 0,02269492 0,09946079 ! response to UV-C GO:0010225 11 6 0,000 0,02269492 0,09927995 ! astrocyte development GO:0014002 15 6 0,000 0,02269492 0,09909977 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02269492 0,09892024 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02269492 0,09874136 ! interaction with symbiont GO:0051702 13 6 0,000 0,02269492 0,09856312 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02269492 0,09838553 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02269492 0,09820858 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02269492 0,09803226 ! response to copper ion GO:0046688 10 6 0,000 0,02269492 0,09785658 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02269492 0,09768152 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02269492 0,09750709 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02269492 0,09733328 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02269492 0,09716009 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02269492 0,09698752 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02269492 0,09681555 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02269492 0,0966442 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02269492 0,09647345 ! hair follicle maturation GO:0048820 7 6 0,000 0,02269492 0,0963033 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02269492 0,09613375 ! Schwann cell development GO:0014044 15 6 0,000 0,02269492 0,0959648 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02269492 0,09579644 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02269492 0,09562867 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02269492 0,09546149 ! subpallium development GO:0021544 10 6 0,000 0,02269492 0,09529489 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02269492 0,09512887 ! histone ubiquitination GO:0016574 8 6 0,000 0,02269492 0,09496343 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02269492 0,09479856 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02269492 0,09463427 ! G2 phase GO:0051319 16 6 0,000 0,02269492 0,09447054 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02269492 0,09430738 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02269492 0,09414478 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02269492 0,09398274 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02269492 0,09382126 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02269492 0,09366033 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02269492 0,09349995 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02269492 0,09334012 ! receptor internalization GO:0031623 10 6 0,000 0,02269492 0,09318084 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02269492 0,0930221 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02269492 0,0928639 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02269492 0,09270623 ! protein deubiquitination GO:0016579 14 6 0,000 0,02269492 0,0925491 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02269492 0,09239251 ! protein destabilization GO:0031648 9 6 0,000 0,02269492 0,09223644 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02269492 0,0920809 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02269492 0,09192588 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02269492 0,09177138 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02269492 0,0916174 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02269492 0,09146394 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02269492 0,09131099 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02269492 0,09115855 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02269492 0,09100662 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02269492 0,09085519 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02269492 0,09070427 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02269492 0,09055385 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02269492 0,09040393 ! catecholamine transport GO:0051937 9 6 0,000 0,02269492 0,0902545 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02269492 0,09010556 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02269492 0,08995712 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02269492 0,08980916 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02269492 0,08966169 ! maternal placenta development GO:0001893 12 6 0,000 0,02269492 0,08951471 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02269492 0,0893682 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02269492 0,08922218 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02269492 0,08907663 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02269492 0,08893155 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02269492 0,08878694 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02269492 0,08864281 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02269492 0,08849914 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,02284608 0,08894443 ! ear development GO:0043583 103 62 1,000 0,02354958 0,09153521 ! viral reproductive process GO:0022415 126 62 1,000 0,02354958 0,09138757 ! detection of external stimulus GO:0009581 91 63 1,000 0,02426193 0,09400033 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,02426193 0,09384921 ! tRNA transcription GO:0009304 14 7 0,000 0,02642744 0,10206168 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02642744 0,10189812 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02642744 0,10173509 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02642744 0,10157257 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02642744 0,10141057 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02642744 0,10124909 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02642744 0,10108812 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02642744 0,10092766 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02642744 0,10076772 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02642744 0,10060827 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02642744 0,10044933 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02642744 0,1002909 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02642744 0,10013296 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02642744 0,09997552 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02642744 0,09981857 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02642744 0,09966211 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02642744 0,09950615 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02642744 0,09935067 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02642744 0,09919568 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02642744 0,09904117 ! glycolipid transport GO:0046836 10 7 0,000 0,02642744 0,09888714 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02642744 0,09873358 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02642744 0,09858051 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02642744 0,09842791 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02642744 0,09827578 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02642744 0,09812412 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02642744 0,09797292 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02642744 0,0978222 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02642744 0,09767193 ! mRNA stabilization GO:0048255 18 7 0,000 0,02642744 0,09752213 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02642744 0,09737278 ! fibril organization GO:0043206 16 7 0,000 0,02642744 0,0972239 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02642744 0,09707546 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02642744 0,09692748 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02642744 0,09677995 ! lipoprotein transport GO:0042953 14 7 0,000 0,02642744 0,09663287 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02642744 0,09648623 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02642744 0,09634004 ! rhythmic behavior GO:0007622 15 7 0,000 0,02642744 0,09619429 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02642744 0,09604899 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02642744 0,09590411 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02642744 0,09575968 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02642744 0,09561568 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02642744 0,09547211 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02642744 0,09532898 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02642744 0,09518627 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02642744 0,09504399 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02642744 0,09490213 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02642744 0,0947607 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02642744 0,09461968 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02642744 0,09447909 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02642744 0,09433891 ! spinal cord patterning GO:0021511 13 7 0,000 0,02642744 0,09419915 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02642744 0,09405981 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02642744 0,09392087 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02642744 0,09378234 ! adrenal gland development GO:0030325 17 7 0,000 0,02642744 0,09364422 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02642744 0,09350651 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02642744 0,0933692 ! ovulation GO:0030728 9 7 0,000 0,02642744 0,0932323 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02642744 0,0930958 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02642744 0,09295969 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02642744 0,09282398 ! microtubule nucleation GO:0007020 20 7 0,000 0,02642744 0,09268867 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02642744 0,09255375 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02642744 0,09241923 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02642744 0,09228509 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02642744 0,09215135 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02642744 0,09201799 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02642744 0,09188501 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02642744 0,09175242 ! galactose metabolic process GO:0006012 13 7 0,000 0,02642744 0,09162021 ! vesicle fusion GO:0006906 17 7 0,000 0,02642744 0,09148839 ! response to dietary excess GO:0002021 8 7 0,000 0,02642744 0,09135694 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02642744 0,09122587 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02642744 0,09109517 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,02642744 0,09096485 ! organ growth GO:0035265 15 7 0,000 0,02642744 0,0908349 ! purine salvage GO:0043101 10 7 0,000 0,02642744 0,09070532 ! nucleoside transport GO:0015858 8 7 0,000 0,02642744 0,09057611 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02642744 0,09044727 ! parturition GO:0007567 14 7 0,000 0,02642744 0,09031879 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02642744 0,09019068 ! rRNA modification GO:0000154 14 7 0,000 0,02642744 0,09006293 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02642744 0,08993554 ! spindle checkpoint GO:0031577 15 7 0,000 0,02642744 0,08980851 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02642744 0,08968185 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02642744 0,08955553 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02642744 0,08942958 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02642744 0,08930397 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02642744 0,08917872 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02642744 0,08905382 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02642744 0,08892927 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02642744 0,08880507 ! fibrinolysis GO:0042730 10 7 0,000 0,02642744 0,08868121 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02642744 0,0885577 ! eating behavior GO:0042755 7 7 0,000 0,02642744 0,08843453 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02642744 0,08831171 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02642744 0,08818922 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02642744 0,08806708 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02642744 0,08794527 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02642744 0,0878238 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02642744 0,08770266 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02642744 0,08758186 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02642744 0,08746139 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02642744 0,08734125 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02642744 0,08722144 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02642744 0,08710196 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02642744 0,0869828 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02642744 0,08686397 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02642744 0,08674547 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02642744 0,08662729 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02642744 0,08650943 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02642744 0,08639189 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02642744 0,08627467 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02642744 0,08615776 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02642744 0,08604117 ! transcription termination GO:0006353 13 7 0,000 0,02642744 0,0859249 ! response to tumor cell GO:0002347 13 7 0,000 0,02642744 0,08580894 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02642744 0,0856933 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02642744 0,08557797 ! anaphase GO:0051322 17 7 0,000 0,02642744 0,08546294 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02642744 0,08534823 ! axonal fasciculation GO:0007413 18 7 0,000 0,02642744 0,08523382 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02642744 0,08511972 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02642744 0,08500592 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02642744 0,08489243 ! diuresis GO:0030146 12 7 0,000 0,02642744 0,08477924 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02642744 0,08466635 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02642744 0,08455376 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02642744 0,08444147 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02642744 0,08432948 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02642744 0,08421779 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02642744 0,08410639 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02642744 0,08399528 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02642744 0,08388447 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02642744 0,08377395 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02642744 0,08366372 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02642744 0,08355378 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02642744 0,08344413 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02642744 0,08333477 ! lymph node development GO:0048535 10 7 0,000 0,02642744 0,08322569 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02642744 0,0831169 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02642744 0,08300839 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02642744 0,08290017 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02642744 0,08279222 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02642744 0,08268456 ! adult feeding behavior GO:0008343 9 7 0,000 0,02642744 0,08257718 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02642744 0,08247008 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02642744 0,08236325 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02642744 0,0822567 ! muscle adaptation GO:0043500 14 7 0,000 0,02642744 0,08215042 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02642744 0,08204442 ! retina homeostasis GO:0001895 12 7 0,000 0,02642744 0,0819387 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02642744 0,08183324 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02642744 0,08172806 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02642744 0,08162314 ! protein prenylation GO:0018342 18 7 0,000 0,02642744 0,0815185 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02642744 0,08141412 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02642744 0,08131001 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02642744 0,08120617 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,02719825 0,08346811 ! lung development GO:0030324 144 67 1,000 0,02719825 0,08336178 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,02795369 0,08556815 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,02795369 0,08545943 ! viral reproduction GO:0016032 134 68 1,000 0,02795369 0,08535098 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02871751 0,08757203 ! urogenital system development GO:0001655 137 69 1,000 0,02871751 0,08746118 ! antigen processing and presentation GO:0019882 104 69 1,000 0,02871751 0,08735061 ! respiratory tube development GO:0030323 150 70 1,000 0,02948966 0,089586 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03014584 0,09146391 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03014584 0,09134872 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03014584 0,09123382 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03014584 0,0911192 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03014584 0,09100487 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03014584 0,09089083 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03014584 0,09077708 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03014584 0,09066361 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03014584 0,09055042 ! meiotic prophase I GO:0007128 13 8 0,000 0,03014584 0,09043751 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03014584 0,09032489 ! UTP metabolic process GO:0046051 8 8 0,000 0,03014584 0,09021254 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03014584 0,09010048 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03014584 0,08998869 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03014584 0,08987718 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03014584 0,08976595 ! succinate metabolic process GO:0006105 14 8 0,000 0,03014584 0,08965499 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03014584 0,0895443 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03014584 0,08943389 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03014584 0,08932375 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03014584 0,08921388 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03014584 0,08910428 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03014584 0,08899495 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03014584 0,08888589 ! reflex GO:0060004 16 8 0,000 0,03014584 0,08877709 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03014584 0,08866856 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03014584 0,0885603 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03014584 0,0884523 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03014584 0,08834456 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03014584 0,08823709 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03014584 0,08812987 ! pigment granule organization GO:0048753 16 8 0,000 0,03014584 0,08802292 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03014584 0,08791622 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03014584 0,08780979 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03014584 0,08770361 ! histidine metabolic process GO:0006547 16 8 0,000 0,03014584 0,08759769 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03014584 0,08749202 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03014584 0,08738661 ! glycine catabolic process GO:0006546 13 8 0,000 0,03014584 0,08728145 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03014584 0,08717654 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03014584 0,08707189 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03014584 0,08696749 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03014584 0,08686333 ! melanin metabolic process GO:0006582 15 8 0,000 0,03014584 0,08675943 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03014584 0,08665578 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03014584 0,08655237 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03014584 0,08644921 ! macrophage activation GO:0042116 12 8 0,000 0,03014584 0,08634629 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03014584 0,08624362 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03014584 0,08614119 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03014584 0,08603901 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03014584 0,08593707 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03014584 0,08583537 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03014584 0,08573391 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03014584 0,08563269 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03014584 0,0855317 ! osteoblast development GO:0002076 16 8 0,000 0,03014584 0,08543096 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03014584 0,08533045 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03014584 0,08523018 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03014584 0,08513015 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03014584 0,08503034 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03014584 0,08493078 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03014584 0,08483144 ! response to UV-B GO:0010224 16 8 0,000 0,03014584 0,08473234 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03014584 0,08463347 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03014584 0,08453483 ! intermediate filament organization GO:0045109 12 8 0,000 0,03014584 0,08443642 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03014584 0,08433824 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03014584 0,08424028 ! cellular extravasation GO:0045123 12 8 0,000 0,03014584 0,08414256 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03014584 0,08404506 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03014584 0,08394778 ! response to antibiotic GO:0046677 11 8 0,000 0,03014584 0,08385073 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03014584 0,08375391 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03014584 0,08365731 ! DNA topological change GO:0006265 12 8 0,000 0,03014584 0,08356093 ! response to tropane GO:0014073 15 8 0,000 0,03014584 0,08346477 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03014584 0,08336883 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,03014584 0,08327312 ! melanosome transport GO:0032402 13 8 0,000 0,03014584 0,08317762 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03014584 0,08308234 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03014584 0,08298728 ! mast cell activation GO:0045576 14 8 0,000 0,03014584 0,08289244 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03014584 0,08279781 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03014584 0,0827034 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03014584 0,08260921 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03014584 0,08251523 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03014584 0,08242146 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03014584 0,0823279 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03014584 0,08223456 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03014584 0,08214143 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03014584 0,08204851 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03014584 0,0819558 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03014584 0,0818633 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03014584 0,08177101 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03014584 0,08167892 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03014584 0,08158705 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03014584 0,08149538 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03014584 0,08140391 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03014584 0,08131265 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03014584 0,08122159 ! hormone catabolic process GO:0042447 17 8 0,000 0,03014584 0,08113074 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03014584 0,08104009 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03014584 0,08094965 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03014584 0,0808594 ! ATP catabolic process GO:0006200 11 8 0,000 0,03014584 0,08076936 ! blastocyst growth GO:0001832 19 8 0,000 0,03014584 0,08067952 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03014584 0,08058987 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03014584 0,08050043 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03014584 0,08041118 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03014584 0,08032213 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03014584 0,08023328 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03014584 0,08014462 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03014584 0,08005616 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03014584 0,0799679 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03014584 0,07987983 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03014584 0,07979195 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03014584 0,07970427 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03014584 0,07961678 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03014584 0,07952948 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03014584 0,07944237 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03014584 0,07935545 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03014584 0,07926873 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03014584 0,07918219 ! reproductive structure development GO:0048608 113 71 1,000 0,03027004 0,07942173 ! regulation of caspase activity GO:0043281 122 72 1,000 0,0310586 0,08140196 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0310586 0,08131338 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,0310586 0,081225 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,0310586 0,0811368 ! respiratory system development GO:0060541 153 72 1,000 0,0310586 0,0810488 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03265995 0,08513524 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,03265995 0,08504311 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,03347259 0,08706491 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03385015 0,08795191 ! axon extension GO:0048675 15 9 0,000 0,03385015 0,08785703 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03385015 0,08776236 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03385015 0,08766789 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03385015 0,08757362 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03385015 0,08747956 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03385015 0,08738569 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03385015 0,08729203 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03385015 0,08719857 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03385015 0,08710531 ! phosphate transport GO:0006817 19 9 0,000 0,03385015 0,08701225 ! reproductive behavior GO:0019098 19 9 0,000 0,03385015 0,08691939 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03385015 0,08682672 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03385015 0,08673426 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03385015 0,08664199 ! GTP metabolic process GO:0046039 9 9 0,000 0,03385015 0,08654991 ! RNA methylation GO:0001510 15 9 0,000 0,03385015 0,08645803 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03385015 0,08636635 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03385015 0,08627486 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03385015 0,08618356 ! artery development GO:0060840 24 9 0,000 0,03385015 0,08609246 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03385015 0,08600155 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03385015 0,08591083 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03385015 0,0858203 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03385015 0,08572997 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03385015 0,08563982 ! chemosensory behavior GO:0007635 20 9 0,000 0,03385015 0,08554986 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03385015 0,08546009 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03385015 0,08537051 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03385015 0,08528112 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03385015 0,08519191 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03385015 0,08510289 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03385015 0,08501406 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03385015 0,08492541 ! protein targeting to ER GO:0045047 22 9 0,000 0,03385015 0,08483694 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03385015 0,08474866 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03385015 0,08466057 ! T cell selection GO:0045058 23 9 0,000 0,03385015 0,08457266 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03385015 0,08448492 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03385015 0,08439737 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03385015 0,08431001 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03385015 0,08422282 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03385015 0,08413581 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03385015 0,08404899 ! mannose metabolic process GO:0006013 13 9 0,000 0,03385015 0,08396234 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03385015 0,08387587 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03385015 0,08378957 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03385015 0,08370346 ! receptor clustering GO:0043113 18 9 0,000 0,03385015 0,08361752 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03385015 0,08353176 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03385015 0,08344618 ! ruffle organization GO:0031529 15 9 0,000 0,03385015 0,08336076 ! retinol metabolic process GO:0042572 18 9 0,000 0,03385015 0,08327553 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03385015 0,08319047 ! behavioral fear response GO:0001662 22 9 0,000 0,03385015 0,08310558 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03385015 0,08302086 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03385015 0,08293632 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03385015 0,08285195 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03385015 0,08276775 ! protein heterooligomerization GO:0051291 16 9 0,000 0,03385015 0,08268372 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03385015 0,08259986 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03385015 0,08251618 ! segment specification GO:0007379 13 9 0,000 0,03385015 0,08243266 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03385015 0,08234931 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03385015 0,08226613 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03385015 0,08218311 ! response to amine stimulus GO:0014075 13 9 0,000 0,03385015 0,08210027 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03385015 0,08201759 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03385015 0,08193508 ! erythrocyte development GO:0048821 15 9 0,000 0,03385015 0,08185273 ! gas homeostasis GO:0033483 16 9 0,000 0,03385015 0,08177055 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03385015 0,08168853 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03385015 0,08160668 ! renal water homeostasis GO:0003091 14 9 0,000 0,03385015 0,08152499 ! postreplication repair GO:0006301 22 9 0,000 0,03385015 0,08144347 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03385015 0,0813621 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03385015 0,08128091 ! icosanoid secretion GO:0032309 15 9 0,000 0,03385015 0,08119987 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03385015 0,08111899 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03385015 0,08103828 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03385015 0,08095772 ! regulation of cell division GO:0051302 15 9 0,000 0,03385015 0,08087733 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03385015 0,08079709 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03385015 0,08071701 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03385015 0,0806371 ! sterol catabolic process GO:0016127 11 9 0,000 0,03385015 0,08055734 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03385015 0,08047773 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03385015 0,08039829 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03385015 0,080319 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03385015 0,08023987 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03385015 0,08016089 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03385015 0,08008207 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03385015 0,08000341 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03385015 0,07992489 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03385015 0,07984654 ! purine base metabolic process GO:0006144 21 9 0,000 0,03385015 0,07976833 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03385015 0,07969028 ! pigment granule transport GO:0051904 17 9 0,000 0,03385015 0,07961238 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03385015 0,07953464 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03385015 0,07945704 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03385015 0,0793796 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03385015 0,0793023 ! mitochondrion localization GO:0051646 15 9 0,000 0,03385015 0,07922516 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,03429311 0,08018389 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,03595752 0,08399398 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,03680128 0,08588154 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,03680128 0,08579832 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,03680128 0,08571526 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03754044 0,08735232 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03754044 0,08726793 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03754044 0,08718369 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03754044 0,08709962 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03754044 0,08701571 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03754044 0,08693196 ! synapsis GO:0007129 13 10 0,000 0,03754044 0,08684837 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03754044 0,08676494 ! N-glycan processing GO:0006491 20 10 0,000 0,03754044 0,08668167 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03754044 0,08659856 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03754044 0,08651562 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03754044 0,08643283 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03754044 0,08635019 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03754044 0,08626772 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03754044 0,0861854 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03754044 0,08610324 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03754044 0,08602124 ! androgen metabolic process GO:0008209 17 10 0,000 0,03754044 0,08593939 ! phospholipid efflux GO:0033700 16 10 0,000 0,03754044 0,0858577 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03754044 0,08577617 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03754044 0,08569478 ! lung alveolus development GO:0048286 26 10 0,000 0,03754044 0,08561356 ! pathogenesis GO:0009405 13 10 0,000 0,03754044 0,08553248 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03754044 0,08545156 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03754044 0,0853708 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03754044 0,08529018 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03754044 0,08520972 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03754044 0,08512941 ! endoderm development GO:0007492 16 10 0,000 0,03754044 0,08504925 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03754044 0,08496924 ! arginine catabolic process GO:0006527 13 10 0,000 0,03754044 0,08488938 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03754044 0,08480967 ! proline metabolic process GO:0006560 13 10 0,000 0,03754044 0,08473012 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03754044 0,08465071 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03754044 0,08457144 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03754044 0,08449233 ! V(D)J recombination GO:0033151 28 10 0,000 0,03754044 0,08441337 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03754044 0,08433455 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03754044 0,08425588 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03754044 0,08417736 ! B cell proliferation GO:0042100 18 10 0,000 0,03754044 0,08409898 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03754044 0,08402075 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03754044 0,08394266 ! multicellular organism growth GO:0035264 18 10 0,000 0,03754044 0,08386472 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03754044 0,08378692 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03754044 0,08370927 ! epithelial cell development GO:0002064 20 10 0,000 0,03754044 0,08363176 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03754044 0,0835544 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03754044 0,08347717 ! macroautophagy GO:0016236 17 10 0,000 0,03754044 0,0834001 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03754044 0,08332316 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03754044 0,08324636 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03754044 0,08316971 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03754044 0,0830932 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,03754044 0,08301682 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03754044 0,08294059 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03754044 0,0828645 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03754044 0,08278855 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03754044 0,08271273 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03754044 0,08263706 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03754044 0,08256152 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03754044 0,08248612 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03754044 0,08241086 ! response to dsRNA GO:0043331 20 10 0,000 0,03754044 0,08233574 ! DNA ligation GO:0006266 19 10 0,000 0,03754044 0,08226075 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03754044 0,0821859 ! melanosome localization GO:0032400 16 10 0,000 0,03754044 0,08211118 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03754044 0,08203661 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03754044 0,08196216 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03754044 0,08188785 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03754044 0,08181368 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03754044 0,08173964 ! mRNA cleavage GO:0006379 17 10 0,000 0,03754044 0,08166574 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03754044 0,08159196 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03754044 0,08151832 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03754044 0,08144482 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03754044 0,08137144 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03754044 0,0812982 ! salivary gland development GO:0007431 27 10 0,000 0,03754044 0,08122509 ! prophase GO:0051324 15 10 0,000 0,03754044 0,08115211 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03754044 0,08107927 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03754044 0,08100655 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03754044 0,08093396 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03754044 0,08086151 ! midbrain development GO:0030901 13 10 0,000 0,03754044 0,08078918 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03754044 0,08071698 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03754044 0,08064491 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03754044 0,08057297 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03754044 0,08050116 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03754044 0,08042948 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03754044 0,08035792 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03754044 0,08028649 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,03754044 0,08021519 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,03754044 0,08014401 ! oocyte development GO:0048599 17 10 0,000 0,03754044 0,08007296 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03754044 0,08000204 ! blastocyst formation GO:0001825 17 10 0,000 0,03754044 0,07993124 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03754044 0,07986057 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03754044 0,07979002 ! activation of innate immune response GO:0002218 12 10 0,000 0,03754044 0,0797196 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03754044 0,0796493 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03754044 0,07957912 ! response to nicotine GO:0035094 20 10 0,000 0,03754044 0,07950907 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03754044 0,07943914 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03754044 0,07936933 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03754044 0,07929965 ! localization within membrane GO:0051668 20 10 0,000 0,03754044 0,07923009 ! response to metal ion GO:0010038 140 80 1,000 0,03765263 0,07939722 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,03765263 0,07932769 ! protein import into nucleus GO:0006606 158 80 1,000 0,03765263 0,07925829 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,03851152 0,08099537 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,03851152 0,08092463 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,03851152 0,08085402 ! nuclear import GO:0051170 161 81 1,000 0,03851152 0,08078353 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,03851152 0,08071316 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,03937787 0,08245705 ! response to oxygen levels GO:0070482 176 83 1,000 0,04025161 0,08421338 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,04113269 0,08598197 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04121676 0,08608292 ! respiratory burst GO:0045730 17 11 0,000 0,04121676 0,08600826 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04121676 0,08593373 ! neuron fate specification GO:0048665 17 11 0,000 0,04121676 0,08585932 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04121676 0,08578505 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04121676 0,08571091 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,04121676 0,08563689 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04121676 0,085563 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04121676 0,08548924 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04121676 0,08541561 ! response to pain GO:0048265 24 11 0,000 0,04121676 0,0853421 ! T cell proliferation GO:0042098 26 11 0,000 0,04121676 0,08526872 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04121676 0,08519546 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04121676 0,08512233 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04121676 0,08504933 ! bone resorption GO:0045453 16 11 0,000 0,04121676 0,08497645 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04121676 0,0849037 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04121676 0,08483107 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04121676 0,08475856 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04121676 0,08468618 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04121676 0,08461392 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04121676 0,08454179 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04121676 0,08446978 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04121676 0,08439789 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04121676 0,08432612 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04121676 0,08425448 ! lipid digestion GO:0044241 18 11 0,000 0,04121676 0,08418295 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04121676 0,08411155 ! UV protection GO:0009650 19 11 0,000 0,04121676 0,08404027 ! adult heart development GO:0007512 14 11 0,000 0,04121676 0,08396911 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04121676 0,08389807 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04121676 0,08382715 ! temperature homeostasis GO:0001659 17 11 0,000 0,04121676 0,08375635 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04121676 0,08368567 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04121676 0,08361511 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04121676 0,08354467 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04121676 0,08347434 ! regulation of organ growth GO:0046620 13 11 0,000 0,04121676 0,08340414 ! pigment granule localization GO:0051875 20 11 0,000 0,04121676 0,08333405 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04121676 0,08326408 ! vasoconstriction GO:0042310 18 11 0,000 0,04121676 0,08319423 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04121676 0,08312449 ! embryonic axis specification GO:0000578 18 11 0,000 0,04121676 0,08305487 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04121676 0,08298537 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04121676 0,08291599 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04121676 0,08284672 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04121676 0,08277756 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04121676 0,08270852 ! zymogen activation GO:0031638 15 11 0,000 0,04121676 0,0826396 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04121676 0,08257079 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04121676 0,0825021 ! nucleosome positioning GO:0016584 15 11 0,000 0,04121676 0,08243352 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04121676 0,08236505 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04121676 0,0822967 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04121676 0,08222846 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04121676 0,08216033 ! acid secretion GO:0046717 18 11 0,000 0,04121676 0,08209232 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04121676 0,08202442 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04121676 0,08195663 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04121676 0,08188895 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04121676 0,08182139 ! oocyte differentiation GO:0009994 18 11 0,000 0,04121676 0,08175393 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04121676 0,08168659 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04121676 0,08161936 ! cholesterol efflux GO:0033344 19 11 0,000 0,04121676 0,08155224 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04121676 0,08148523 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04121676 0,08141832 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04121676 0,08135153 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04121676 0,08128485 ! embryonic gut development GO:0048566 15 11 0,000 0,04121676 0,08121828 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04121676 0,08115182 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04121676 0,08108546 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04121676 0,08101922 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04121676 0,08095308 ! defense response to fungus GO:0050832 13 11 0,000 0,04121676 0,08088705 ! developmental induction GO:0031128 19 11 0,000 0,04121676 0,08082112 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04121676 0,08075531 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04121676 0,0806896 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04121676 0,080624 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04121676 0,0805585 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04121676 0,08049312 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04121676 0,08042783 ! response to unfolded protein GO:0006986 131 85 1,000 0,04202102 0,08193078 ! nucleosome assembly GO:0006334 122 85 1,000 0,04202102 0,08186444 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,04202102 0,08179821 ! response to inorganic substance GO:0010035 153 86 1,000 0,04291655 0,08347391 ! chromatin assembly GO:0031497 124 86 1,000 0,04291655 0,08340648 ! mitochondrion organization GO:0007005 148 86 1,000 0,04291655 0,08333916 ! protein localization in nucleus GO:0034504 176 87 1,000 0,04381921 0,0850234 ! regulation of protein transport GO:0051223 154 87 1,000 0,04381921 0,08495489 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,04472892 0,08664878 ! regulation of DNA binding GO:0051101 155 88 1,000 0,04472892 0,08657907 ! gland development GO:0048732 206 88 1,000 0,04472892 0,08650947 ! regulation of neurological system process GO:0031644 148 88 1,000 0,04472892 0,08643999 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04487915 0,08666071 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04487915 0,08659121 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04487915 0,08652183 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,04487915 0,08645256 ! virus-host interaction GO:0019048 29 12 0,000 0,04487915 0,08638339 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04487915 0,08631434 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04487915 0,0862454 ! cartilage condensation GO:0001502 20 12 0,000 0,04487915 0,08617657 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04487915 0,08610785 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04487915 0,08603924 ! protein complex disassembly GO:0043241 27 12 0,000 0,04487915 0,08597073 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04487915 0,08590234 ! hippocampus development GO:0021766 26 12 0,000 0,04487915 0,08583406 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,04487915 0,08576588 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04487915 0,08569781 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04487915 0,08562985 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04487915 0,085562 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04487915 0,08549425 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04487915 0,08542662 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04487915 0,08535909 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04487915 0,08529166 ! drug transport GO:0015893 16 12 0,000 0,04487915 0,08522434 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04487915 0,08515713 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04487915 0,08509003 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04487915 0,08502303 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04487915 0,08495613 ! focal adhesion formation GO:0048041 35 12 0,000 0,04487915 0,08488934 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04487915 0,08482266 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04487915 0,08475608 ! forebrain cell migration GO:0021885 21 12 0,000 0,04487915 0,0846896 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04487915 0,08462323 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04487915 0,08455696 ! fear response GO:0042596 26 12 0,000 0,04487915 0,0844908 ! monoamine transport GO:0015844 18 12 0,000 0,04487915 0,08442474 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04487915 0,08435878 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04487915 0,08429293 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04487915 0,08422718 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04487915 0,08416153 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04487915 0,08409598 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04487915 0,08403054 ! protein homotetramerization GO:0051289 21 12 0,000 0,04487915 0,0839652 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04487915 0,08389996 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04487915 0,08383482 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04487915 0,08376978 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04487915 0,08370484 ! cranial nerve development GO:0021545 20 12 0,000 0,04487915 0,08364 ! fucose catabolic process GO:0019317 22 12 0,000 0,04487915 0,08357527 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04487915 0,08351063 ! histone methylation GO:0016571 26 12 0,000 0,04487915 0,08344609 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04487915 0,08338165 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04487915 0,08331732 ! gland morphogenesis GO:0022612 29 12 0,000 0,04487915 0,08325308 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04487915 0,08318894 ! T cell homeostasis GO:0043029 25 12 0,000 0,04487915 0,0831249 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04487915 0,08306096 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04487915 0,08299711 ! spleen development GO:0048536 22 12 0,000 0,04487915 0,08293337 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04487915 0,08286972 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04487915 0,08280617 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04487915 0,08274271 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04487915 0,08267936 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04487915 0,0826161 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04487915 0,08255294 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04487915 0,08248987 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04487915 0,0824269 ! response to cold GO:0009409 17 12 0,000 0,04487915 0,08236403 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04487915 0,08230125 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04487915 0,08223857 ! cellular defense response GO:0006968 114 89 1,000 0,04564563 0,08357944 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,04564563 0,08351588 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,04564563 0,08345242 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,04656927 0,08507643 ! sex differentiation GO:0007548 145 90 1,000 0,04656927 0,08501188 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,04656927 0,08494743 ! sterol metabolic process GO:0016125 152 91 1,000 0,04749977 0,08657912 ! response to protein stimulus GO:0051789 149 91 1,000 0,04749977 0,08651358 ! nucleosome organization GO:0034728 138 92 1,000 0,04843706 0,08815399 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04852768 0,08825215 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04852768 0,0881855 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04852768 0,08811894 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04852768 0,08805249 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04852768 0,08798613 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04852768 0,08791988 ! lipid localization GO:0010876 28 13 0,000 0,04852768 0,08785372 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04852768 0,08778767 ! organelle fusion GO:0048284 32 13 0,000 0,04852768 0,08772171 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04852768 0,08765585 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04852768 0,0875901 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04852768 0,08752444 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04852768 0,08745887 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04852768 0,08739341 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04852768 0,08732805 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04852768 0,08726278 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04852768 0,08719761 ! methionine metabolic process GO:0006555 27 13 0,000 0,04852768 0,08713254 ! plasma membrane organization GO:0007009 24 13 0,000 0,04852768 0,08706756 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04852768 0,08700268 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04852768 0,0869379 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04852768 0,08687321 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04852768 0,08680862 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04852768 0,08674413 ! response to X-ray GO:0010165 25 13 0,000 0,04852768 0,08667973 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04852768 0,08661543 ! exocrine system development GO:0035272 32 13 0,000 0,04852768 0,08655122 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,04852768 0,08648711 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04852768 0,08642309 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04852768 0,08635917 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04852768 0,08629534 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04852768 0,08623161 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04852768 0,08616797 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04852768 0,08610442 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04852768 0,08604097 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04852768 0,08597761 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04852768 0,08591435 ! regulation of cellular pH GO:0030641 22 13 0,000 0,04852768 0,08585118 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04852768 0,0857881 ! ribosome assembly GO:0042255 17 13 0,000 0,04852768 0,08572511 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,04852768 0,08566221 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04852768 0,08559941 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04852768 0,0855367 ! chromatin silencing GO:0006342 26 13 0,000 0,04852768 0,08547408 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04852768 0,08541156 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04852768 0,08534912 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04852768 0,08528678 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04852768 0,08522452 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04852768 0,08516236 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04852768 0,08510029 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04852768 0,08503831 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04852768 0,08497642 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04852768 0,08491462 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04852768 0,08485291 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04852768 0,08479128 ! embryonic placenta development GO:0001892 23 13 0,000 0,04852768 0,08472975 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04852768 0,08466831 ! insulin secretion GO:0030073 23 13 0,000 0,04852768 0,08460696 ! actin filament polymerization GO:0030041 24 13 0,000 0,04852768 0,08454569 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04852768 0,08448451 ! acrosome reaction GO:0007340 18 13 0,000 0,04852768 0,08442343 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,0503318 0,08749878 ! transcription initiation GO:0006352 153 94 1,000 0,0503318 0,0874356 ! rRNA transcription GO:0009303 25 14 0,000 0,05216239 0,0905503 ! lactation GO:0007595 26 14 0,000 0,05216239 0,09048501 ! reproductive cellular process GO:0048610 20 14 0,000 0,05216239 0,09041982 ! tRNA modification GO:0006400 20 14 0,000 0,05216239 0,09035472 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05216239 0,09028972 ! regulation of S phase GO:0033261 23 14 0,000 0,05216239 0,09022481 ! water transport GO:0006833 21 14 0,000 0,05216239 0,09015999 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05216239 0,09009527 ! non-recombinational repair GO:0000726 25 14 0,000 0,05216239 0,09003064 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05216239 0,0899661 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05216239 0,08990166 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05216239 0,0898373 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05216239 0,08977304 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05216239 0,08970887 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05216239 0,08964479 ! palate development GO:0060021 31 14 0,000 0,05216239 0,08958081 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05216239 0,08951691 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05216239 0,08945311 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05216239 0,0893894 ! arginine metabolic process GO:0006525 17 14 0,000 0,05216239 0,08932577 ! regulation of heart rate GO:0002027 24 14 0,000 0,05216239 0,08926224 ! organic alcohol transport GO:0015850 29 14 0,000 0,05216239 0,0891988 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05216239 0,08913545 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05216239 0,08907219 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05216239 0,08900901 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05216239 0,08894593 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05216239 0,08888294 ! L-amino acid transport GO:0015807 30 14 0,000 0,05216239 0,08882004 ! bone mineralization GO:0030282 17 14 0,000 0,05216239 0,08875722 ! stem cell development GO:0048864 43 14 0,000 0,05216239 0,0886945 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05216239 0,08863186 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05216239 0,08856931 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05216239 0,08850685 ! cerebellum development GO:0021549 21 14 0,000 0,05216239 0,08844448 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05216239 0,08838219 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05216239 0,08831999 ! response to gamma radiation GO:0010332 28 14 0,000 0,05216239 0,08825788 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05216239 0,08819586 ! cofactor transport GO:0051181 26 14 0,000 0,05216239 0,08813393 ! NADP metabolic process GO:0006739 24 14 0,000 0,05216239 0,08807208 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05216239 0,08801032 ! intestinal absorption GO:0050892 25 14 0,000 0,05216239 0,08794864 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05216239 0,08788705 ! oxygen transport GO:0015671 21 14 0,000 0,05216239 0,08782555 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05216239 0,08776413 ! male genitalia development GO:0030539 24 14 0,000 0,05216239 0,0877028 ! regulation of RNA stability GO:0043487 32 14 0,000 0,05216239 0,08764156 ! regulation of axon extension GO:0030516 37 14 0,000 0,05216239 0,0875804 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05216239 0,08751932 ! mRNA transport GO:0051028 169 96 1,000 0,05225295 0,08761018 ! detection of stimulus GO:0051606 151 96 1,000 0,05225295 0,08754917 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,05322328 0,08911289 ! regulation of protein localization GO:0032880 176 97 1,000 0,05322328 0,08905092 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,05420003 0,09062215 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,05518313 0,09220181 GO:0060538|skeletal muscle organ development, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05578334 0,09313998 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05578334 0,09307539 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05578334 0,09301088 ! superoxide anion generation GO:0042554 20 15 0,000 0,05578334 0,09294647 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,05578334 0,09288215 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05578334 0,09281792 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05578334 0,09275377 ! copper ion transport GO:0006825 20 15 0,000 0,05578334 0,09268971 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05578334 0,09262575 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05578334 0,09256187 ! sulfate transport GO:0008272 23 15 0,000 0,05578334 0,09249807 ! response to cAMP GO:0051591 22 15 0,000 0,05578334 0,09243437 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05578334 0,09237075 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05578334 0,09230723 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05578334 0,09224378 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05578334 0,09218043 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05578334 0,09211716 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05578334 0,09205398 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05578334 0,09199089 ! pituitary gland development GO:0021983 29 15 0,000 0,05578334 0,09192788 ! vesicle coating GO:0006901 33 15 0,000 0,05578334 0,09186496 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05578334 0,09180212 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05578334 0,09173938 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,05578334 0,09167671 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05578334 0,09161413 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,05578334 0,09155164 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05578334 0,09148923 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05578334 0,09142691 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05578334 0,09136467 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05578334 0,09130252 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05578334 0,09124045 ! histone deacetylation GO:0016575 20 15 0,000 0,05578334 0,09117847 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05578334 0,09111657 ! tissue regeneration GO:0042246 26 15 0,000 0,05578334 0,09105475 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05578334 0,09099302 ! water homeostasis GO:0030104 27 15 0,000 0,05578334 0,09093137 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05578334 0,09086981 ! muscle maintenance GO:0046716 26 15 0,000 0,05578334 0,09080833 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05578334 0,09074693 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05578334 0,09068561 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05578334 0,09062438 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05578334 0,09056323 ! cell killing GO:0001906 29 15 0,000 0,05578334 0,09050216 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05578334 0,09044118 ! detection of bacterium GO:0016045 18 15 0,000 0,05578334 0,09038027 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,05578334 0,09031945 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05578334 0,09025871 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05578334 0,09019806 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05578334 0,09013748 ! peptide hormone processing GO:0016486 23 15 0,000 0,05578334 0,09007698 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05939057 0,0958375 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,05939057 0,09577326 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05939057 0,09570911 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05939057 0,09564505 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05939057 0,09558108 ! bone remodeling GO:0046849 27 16 0,000 0,05939057 0,09551718 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05939057 0,09545338 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05939057 0,09538966 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05939057 0,09532602 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05939057 0,09526247 ! startle response GO:0001964 28 16 0,000 0,05939057 0,09519901 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05939057 0,09513562 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05939057 0,09507233 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05939057 0,09500911 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05939057 0,09494599 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05939057 0,09488294 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05939057 0,09481998 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05939057 0,0947571 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05939057 0,09469431 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05939057 0,09463159 ! response to osmotic stress GO:0006970 25 16 0,000 0,05939057 0,09456897 ! lysosomal transport GO:0007041 26 16 0,000 0,05939057 0,09450642 ! fructose metabolic process GO:0006000 25 16 0,000 0,05939057 0,09444396 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05939057 0,09438158 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05939057 0,09431928 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05939057 0,09425706 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05939057 0,09419493 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05939057 0,09413288 ! axon cargo transport GO:0008088 43 16 0,000 0,05939057 0,09407091 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05939057 0,09400902 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05939057 0,09394721 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,05939057 0,09388548 ! neuron recognition GO:0008038 35 16 0,000 0,05939057 0,09382384 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05939057 0,09376228 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05939057 0,09370079 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05939057 0,09363939 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05939057 0,09357807 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05939057 0,09351682 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05939057 0,09345566 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05939057 0,09339458 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05939057 0,09333358 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05939057 0,09327266 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05939057 0,09321181 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05939057 0,09315105 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05939057 0,09309036 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,05939057 0,09302976 ! defense response to virus GO:0051607 37 16 0,000 0,05939057 0,09296923 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06298414 0,09853045 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06298414 0,09846643 ! metencephalon development GO:0022037 30 17 0,000 0,06298414 0,09840249 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06298414 0,09833864 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06298414 0,09827486 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06298414 0,09821117 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06298414 0,09814756 ! signal complex assembly GO:0007172 41 17 0,000 0,06298414 0,09808404 ! endothelial cell migration GO:0043542 28 17 0,000 0,06298414 0,09802059 ! inositol metabolic process GO:0006020 28 17 0,000 0,06298414 0,09795723 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06298414 0,09789395 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06298414 0,09783076 ! glial cell development GO:0021782 27 17 0,000 0,06298414 0,09776764 ! limbic system development GO:0021761 36 17 0,000 0,06298414 0,0977046 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06298414 0,09764165 ! adult walking behavior GO:0007628 33 17 0,000 0,06298414 0,09757878 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06298414 0,09751598 ! heart looping GO:0001947 30 17 0,000 0,06298414 0,09745327 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06298414 0,09739064 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06298414 0,09732809 ! myoblast differentiation GO:0045445 45 17 0,000 0,06298414 0,09726562 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06298414 0,09720323 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06298414 0,09714092 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06298414 0,09707869 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06298414 0,09701654 ! glycine metabolic process GO:0006544 28 17 0,000 0,06298414 0,09695447 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,06298414 0,09689248 ! NAD metabolic process GO:0019674 29 17 0,000 0,06298414 0,09683057 ! membrane budding GO:0006900 37 17 0,000 0,06298414 0,09676874 ! DNA integration GO:0015074 29 17 0,000 0,06298414 0,09670698 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06298414 0,09664531 ! regulation of protein binding GO:0043393 33 17 0,000 0,06298414 0,09658371 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06298414 0,09652219 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06298414 0,09646075 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06298414 0,09639939 ! genitalia development GO:0048806 30 17 0,000 0,06298414 0,09633811 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06298414 0,0962769 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06298414 0,09621577 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06298414 0,09615472 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06298414 0,09609375 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06298414 0,09603285 ! steroid catabolic process GO:0006706 31 17 0,000 0,06298414 0,09597203 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06298414 0,09591129 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06298414 0,09585063 ! gas transport GO:0015669 25 17 0,000 0,06298414 0,09579004 ! organic cation transport GO:0015695 31 17 0,000 0,06298414 0,09572953 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06298414 0,09566909 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06298414 0,09560873 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06298414 0,09554845 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06298414 0,09548824 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0665641 0,10085216 ! neuron maturation GO:0042551 42 18 0,000 0,0665641 0,10078869 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,0665641 0,1007253 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,0665641 0,10066199 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0665641 0,10059876 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0665641 0,10053561 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0665641 0,10047254 ! memory GO:0007613 31 18 0,000 0,0665641 0,10040955 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0665641 0,10034663 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0665641 0,1002838 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0665641 0,10022104 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,0665641 0,10015837 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,0665641 0,10009577 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,0665641 0,10003325 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,0665641 0,0999708 ! response to retinoic acid GO:0032526 26 18 0,000 0,0665641 0,09990844 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,0665641 0,09984615 ! response to fungus GO:0009620 21 18 0,000 0,0665641 0,09978394 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,0665641 0,09972181 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0665641 0,09965975 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0665641 0,09959778 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0665641 0,09953588 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0665641 0,09947405 ! vitamin transport GO:0051180 27 18 0,000 0,0665641 0,09941231 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0665641 0,09935064 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0665641 0,09928904 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,0665641 0,09922753 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,0665641 0,09916608 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,0665641 0,09910472 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,0665641 0,09904343 ! nerve development GO:0021675 28 18 0,000 0,0665641 0,09898222 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0665641 0,09892108 ! protein secretion GO:0009306 39 19 0,000 0,0701305 0,10415678 ! positive regulation of translation GO:0045727 30 19 0,000 0,0701305 0,10409253 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0701305 0,10402835 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0701305 0,10396426 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0701305 0,10390024 ! skin development GO:0043588 36 19 0,000 0,0701305 0,1038363 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0701305 0,10377244 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0701305 0,10370866 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0701305 0,10364496 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0701305 0,10358133 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0701305 0,10351778 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0701305 0,10345432 ! cerebral cortex development GO:0021987 36 19 0,000 0,0701305 0,10339092 ! pigmentation during development GO:0048066 41 19 0,000 0,0701305 0,10332761 ! response to vitamin A GO:0033189 27 19 0,000 0,0701305 0,10326437 ! heme metabolic process GO:0042168 36 19 0,000 0,0701305 0,10320122 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0701305 0,10313813 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0701305 0,10307513 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0701305 0,1030122 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0701305 0,10294935 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0701305 0,10288658 ! peptide cross-linking GO:0018149 37 19 0,000 0,0701305 0,10282388 ! heart process GO:0003015 30 19 0,000 0,0701305 0,10276126 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0701305 0,10269871 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0701305 0,10263625 ! visual learning GO:0008542 36 19 0,000 0,0701305 0,10257385 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0701305 0,10251154 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0701305 0,10244929 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0701305 0,10238713 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0701305 0,10232504 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0701305 0,10226302 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0701305 0,10220108 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0701305 0,10213922 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0701305 0,10207743 ! cilium assembly GO:0042384 37 19 0,000 0,0701305 0,10201571 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0701305 0,10195407 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0736834 0,1070545 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0736834 0,10698989 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0736834 0,10692536 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0736834 0,10686091 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0736834 0,10679654 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0736834 0,10673224 ! response to vitamin GO:0033273 31 20 0,000 0,0736834 0,10666802 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0736834 0,10660388 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,0736834 0,10653981 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0736834 0,10647583 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0736834 0,10641192 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0736834 0,10634808 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0736834 0,10628432 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0736834 0,10622064 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0736834 0,10615704 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0736834 0,10609351 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0736834 0,10603005 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,0736834 0,10596668 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0736834 0,10590338 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0736834 0,10584015 ! body fluid secretion GO:0007589 31 20 0,000 0,0736834 0,105777 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0736834 0,10571392 ! peptide secretion GO:0002790 35 20 0,000 0,0736834 0,10565092 ! stem cell differentiation GO:0048863 53 20 0,000 0,0736834 0,105588 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0736834 0,10552515 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0736834 0,10546237 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0736834 0,10539967 ! sensory perception of pain GO:0019233 30 20 0,000 0,0736834 0,10533705 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0736834 0,1052745 ! diencephalon development GO:0021536 34 20 0,000 0,0736834 0,10521202 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0736834 0,10514961 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0736834 0,10508729 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0736834 0,10502503 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0736834 0,10496285 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0736834 0,10490074 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0736834 0,10483871 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0736834 0,10477674 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0736834 0,10471486 ! regulation of glucose import GO:0046324 29 20 0,000 0,0736834 0,10465304 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,0736834 0,1045913 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0736834 0,10452963 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,0736834 0,10446803 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0736834 0,10440651 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0736834 0,10434506 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0736834 0,10428368 ! regulation of cell killing GO:0031341 42 21 0,000 0,07722283 0,10922877 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,07722283 0,10916459 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,07722283 0,10910049 ! hormone secretion GO:0046879 38 21 0,000 0,07722283 0,10903646 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07722283 0,10897251 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,07722283 0,10890864 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,07722283 0,10884484 ! axis specification GO:0009798 38 21 0,000 0,07722283 0,10878111 ! ovarian follicle development GO:0001541 35 21 0,000 0,07722283 0,10871746 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,07722283 0,10865388 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07722283 0,10859038 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07722283 0,10852695 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07722283 0,10846359 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,07722283 0,10840031 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,07722283 0,1083371 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,07722283 0,10827397 ! cytolysis GO:0019835 24 21 0,000 0,07722283 0,10821091 ! vasodilation GO:0042311 39 21 0,000 0,07722283 0,10814792 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07722283 0,10808501 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,07722283 0,10802217 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07722283 0,1079594 ! oogenesis GO:0048477 36 21 0,000 0,07722283 0,10789671 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,07722283 0,10783409 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,07722283 0,10777154 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,07722283 0,10770906 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07722283 0,10764666 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,07722283 0,10758433 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,07722283 0,10752207 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07722283 0,10745988 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07722283 0,10739777 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,07722283 0,10733572 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,07722283 0,10727375 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07722283 0,10721185 ! collagen catabolic process GO:0030574 28 21 0,000 0,07722283 0,10715002 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07722283 0,10708826 ! gut development GO:0048565 39 21 0,000 0,07722283 0,10702657 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08074886 0,11184903 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,08074886 0,11178467 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08074886 0,11172039 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08074886 0,11165618 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08074886 0,11159205 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,08074886 0,11152799 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,08074886 0,111464 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08074886 0,11140009 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08074886 0,11133625 ! regeneration GO:0031099 41 22 0,000 0,08074886 0,11127249 ! keratinization GO:0031424 28 22 0,000 0,08074886 0,11120879 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08074886 0,11114517 ! sensory perception of taste GO:0050909 28 22 0,000 0,08074886 0,11108162 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,08074886 0,11101815 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,08074886 0,11095475 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08074886 0,11089142 ! vacuolar transport GO:0007034 36 22 0,000 0,08074886 0,11082816 ! lysosome organization GO:0007040 41 22 0,000 0,08074886 0,11076497 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08074886 0,11070186 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08074886 0,11063882 ! fucose metabolic process GO:0006004 39 22 0,000 0,08074886 0,11057585 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08074886 0,11051295 ! ureteric bud development GO:0001657 43 22 0,000 0,08074886 0,11045012 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08074886 0,11038736 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08074886 0,11032468 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08074886 0,11026207 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08074886 0,11019952 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08074886 0,11013705 ! sarcomere organization GO:0045214 30 22 0,000 0,08074886 0,11007465 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,08074886 0,11001232 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08074886 0,10995006 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08074886 0,10988787 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08074886 0,10982575 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08074886 0,10976371 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,08426153 0,11447389 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,08426153 0,11440928 ! gluconeogenesis GO:0006094 33 23 0,000 0,08426153 0,11434475 ! viral genome replication GO:0019079 41 23 0,000 0,08426153 0,1142803 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,08426153 0,11421592 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,08426153 0,1141516 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,08426153 0,11408737 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,08426153 0,1140232 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,08426153 0,11395911 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,08426153 0,11389508 ! visual behavior GO:0007632 42 23 0,000 0,08426153 0,11383113 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,08426153 0,11376726 ! response to ethanol GO:0045471 46 23 0,000 0,08426153 0,11370345 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,08426153 0,11363971 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,08426153 0,11357605 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,08426153 0,11351246 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,08426153 0,11344894 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,08426153 0,11338549 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,08426153 0,11332211 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,08426153 0,1132588 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,08426153 0,11319556 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,08426153 0,11313239 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,08426153 0,1130693 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,08426153 0,11300627 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,08426153 0,11294331 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,08426153 0,11288043 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,08426153 0,11281761 ! fatty acid transport GO:0015908 44 23 0,000 0,08426153 0,11275487 ! platelet activation GO:0030168 37 23 0,000 0,08426153 0,11269219 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,08426153 0,11262958 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,08426153 0,11256705 ! hormone transport GO:0009914 40 23 0,000 0,08426153 0,11250458 ! cell-cell recognition GO:0009988 25 23 0,000 0,08426153 0,11244218 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,08426153 0,11237985 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,08426153 0,11231759 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,08426153 0,1122554 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,08426153 0,11219328 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,0877609 0,11678801 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0877609 0,11672345 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,0877609 0,11665896 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0877609 0,11659455 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0877609 0,1165302 ! vesicle docking GO:0048278 47 24 0,000 0,0877609 0,11646593 ! spinal cord development GO:0021510 47 24 0,000 0,0877609 0,11640172 ! vacuole organization GO:0007033 43 24 0,000 0,0877609 0,11633759 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0877609 0,11627353 ! digestive system process GO:0022600 39 24 0,000 0,0877609 0,11620954 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0877609 0,11614561 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0877609 0,11608176 ! regulation of behavior GO:0050795 43 24 0,000 0,0877609 0,11601798 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0877609 0,11595427 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0877609 0,11589063 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0877609 0,11582706 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,0877609 0,11576356 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0877609 0,11570012 ! membrane depolarization GO:0051899 39 24 0,000 0,0877609 0,11563676 ! pallium development GO:0021543 49 24 0,000 0,0877609 0,11557347 ! pentose metabolic process GO:0019321 35 24 0,000 0,0877609 0,11551024 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,0877609 0,11544709 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,0877609 0,115384 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0877609 0,11532099 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0877609 0,11525804 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0877609 0,11519516 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0877609 0,11513235 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0877609 0,11506961 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0877609 0,11500693 ! regulation of amine transport GO:0051952 40 24 0,000 0,0877609 0,11494433 ! protein tetramerization GO:0051262 52 24 0,000 0,0877609 0,11488179 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,09124701 0,11938026 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,09124701 0,11931538 ! myelination GO:0042552 45 25 0,000 0,09124701 0,11925057 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09124701 0,11918583 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,09124701 0,11912116 ! phototransduction GO:0007602 33 25 0,000 0,09124701 0,11905656 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09124701 0,11899204 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,09124701 0,11892758 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,09124701 0,11886319 ! sperm motility GO:0030317 31 25 0,000 0,09124701 0,11879887 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,09124701 0,11873462 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,09124701 0,11867044 ! receptor metabolic process GO:0043112 46 25 0,000 0,09124701 0,11860632 ! chromosome condensation GO:0030261 45 25 0,000 0,09124701 0,11854228 ! response to starvation GO:0042594 42 25 0,000 0,09124701 0,11847831 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09124701 0,1184144 ! neural crest cell development GO:0014032 54 25 0,000 0,09124701 0,11835057 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09124701 0,1182868 ! negative regulation of cell development GO:0010721 73 25 0,000 0,09124701 0,1182231 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,09124701 0,11815948 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,09124701 0,11809591 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09124701 0,11803242 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09124701 0,117969 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09124701 0,11790564 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09124701 0,11784235 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09124701 0,11777913 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09124701 0,11771598 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,09124701 0,1176529 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,09124701 0,11758988 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09124701 0,11752693 ! telomere organization GO:0032200 43 25 0,000 0,09124701 0,11746405 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09124701 0,11740123 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09124701 0,11733848 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09471991 0,12173937 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09471991 0,12167438 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09471991 0,12160945 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09471991 0,12154459 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09471991 0,1214798 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,09471991 0,12141508 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09471991 0,12135043 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09471991 0,12128585 ! molting cycle process GO:0022404 50 26 0,000 0,09471991 0,12122133 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,09471991 0,12115689 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09471991 0,12109251 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,09471991 0,1210282 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09471991 0,12096396 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09471991 0,12089979 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,09471991 0,12083569 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,09471991 0,12077165 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09471991 0,12070769 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09471991 0,12064378 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09471991 0,12057995 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09471991 0,12051619 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,09471991 0,12045249 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09471991 0,12038886 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09471991 0,1203253 ! blastocyst development GO:0001824 49 26 0,000 0,09471991 0,1202618 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09471991 0,12019837 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09471991 0,12013501 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09471991 0,12007171 ! neuron fate commitment GO:0048663 48 27 0,000 0,09817966 0,12439192 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,09817966 0,12432645 ! iron ion transport GO:0006826 59 27 0,000 0,09817966 0,12426105 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,09817966 0,12419572 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09817966 0,12413046 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09817966 0,12406526 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,09817966 0,12400014 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09817966 0,12393508 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,09817966 0,12387009 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,09817966 0,12380517 ! autophagy GO:0006914 41 27 0,000 0,09817966 0,12374031 ! male gonad development GO:0008584 44 27 0,000 0,09817966 0,12367553 ! response to toxin GO:0009636 47 27 0,000 0,09817966 0,12361081 ! primary neural tube formation GO:0014020 51 27 0,000 0,09817966 0,12354616 ! base-excision repair GO:0006284 41 27 0,000 0,09817966 0,12348158 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,09817966 0,12341706 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09817966 0,12335261 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09817966 0,12328823 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09817966 0,12322392 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,09817966 0,12315968 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,1016263 0,12741682 ! circadian rhythm GO:0007623 50 28 0,000 0,1016263 0,12735045 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,1016263 0,12728416 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,1016263 0,12721793 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,1016263 0,12715178 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,1016263 0,12708569 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,1016263 0,12701967 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,1016263 0,12695372 ! synaptogenesis GO:0007416 42 28 0,000 0,1016263 0,12688784 ! lipid oxidation GO:0034440 43 28 0,000 0,1016263 0,12682203 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,1016263 0,12675628 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,1016263 0,12669061 ! translational initiation GO:0006413 65 29 0,000 0,10505988 0,13090319 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10505988 0,13083544 ! regulation of pH GO:0006885 43 29 0,000 0,10505988 0,13076775 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10505988 0,13070014 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10505988 0,13063259 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10505988 0,13056511 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10505988 0,13049771 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10505988 0,13043037 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10505988 0,13036311 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,10505988 0,13029591 ! cell fate determination GO:0001709 60 29 0,000 0,10505988 0,13022878 ! detection of light stimulus GO:0009583 38 29 0,000 0,10505988 0,13016172 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,10505988 0,13009473 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,10505988 0,13002781 ! tissue homeostasis GO:0001894 48 29 0,000 0,10505988 0,12996096 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,10505988 0,12989417 ! zinc ion transport GO:0006829 45 30 0,000 0,10848045 0,13405442 ! membrane docking GO:0022406 61 30 0,000 0,10848045 0,1339856 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,10848045 0,13391686 ! cell junction assembly GO:0034329 78 30 0,000 0,10848045 0,13384818 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10848045 0,13377958 ! acute-phase response GO:0006953 49 30 0,000 0,10848045 0,13371104 ! myofibril assembly GO:0030239 47 30 0,000 0,10848045 0,13364258 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,10848045 0,13357418 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10848045 0,13350586 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,10848045 0,1334376 ! phospholipid transport GO:0015914 51 30 0,000 0,10848045 0,13336942 ! ensheathment of neurons GO:0007272 57 30 0,000 0,10848045 0,1333013 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10848045 0,13323326 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,10848045 0,13316528 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,10848045 0,13309738 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,10848045 0,13302954 ! eye morphogenesis GO:0048592 60 30 0,000 0,10848045 0,13296177 ! regulation of B cell activation GO:0050864 50 30 0,000 0,10848045 0,13289407 ! response to heat GO:0009408 50 30 0,000 0,10848045 0,13282644 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11188806 0,13692913 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,11188806 0,13685951 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11188806 0,13678997 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11188806 0,1367205 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,11188806 0,1366511 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,11188806 0,13658177 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,11188806 0,13651251 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11188806 0,13644332 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,11188806 0,1363742 ! ovulation cycle process GO:0022602 49 31 0,000 0,11188806 0,13630515 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11188806 0,13623616 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,11188806 0,13616725 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,11188806 0,13609841 ! mesoderm formation GO:0001707 69 31 0,000 0,11188806 0,13602964 ! natural killer cell activation GO:0030101 45 31 0,000 0,11188806 0,13596094 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11188806 0,13589231 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11188806 0,13582374 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,11188806 0,13575525 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,11188806 0,13568683 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,11188806 0,13561847 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11528275 0,13966279 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11528275 0,1395925 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11528275 0,13952229 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11528275 0,13945214 ! cholesterol transport GO:0030301 56 32 0,000 0,11528275 0,13938206 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11528275 0,13931206 ! spliceosome assembly GO:0000245 67 32 0,000 0,11528275 0,13924212 ! spindle organization GO:0007051 46 32 0,000 0,11528275 0,13917225 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11528275 0,13910246 ! metanephros development GO:0001656 74 32 0,000 0,11528275 0,13903273 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11528275 0,13896308 ! response to ionizing radiation GO:0010212 65 32 0,000 0,11528275 0,13889349 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11528275 0,13882398 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,11528275 0,13875453 ! muscle cell development GO:0055001 49 32 0,000 0,11528275 0,13868515 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11528275 0,13861584 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,11528275 0,13854661 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,11528275 0,13847744 ! ovulation cycle GO:0042698 51 32 0,000 0,11528275 0,13840834 ! peripheral nervous system development GO:0007422 64 32 0,000 0,11528275 0,1383393 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11528275 0,13827034 ! hindbrain development GO:0030902 61 32 0,000 0,11528275 0,13820145 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11528275 0,13813262 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11528275 0,13806386 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,11528275 0,13799518 ! gene silencing GO:0016458 65 32 0,000 0,11528275 0,13792656 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,11866459 0,14190209 ! post-embryonic development GO:0009791 69 33 0,000 0,11866459 0,14183159 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,11866459 0,14176117 ! protein targeting to membrane GO:0006612 68 33 0,000 0,11866459 0,14169082 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,11866459 0,14162053 ! ceramide metabolic process GO:0006672 64 33 0,000 0,11866459 0,14155032 ! formation of primary germ layer GO:0001704 72 33 0,000 0,11866459 0,14148018 ! cell fate specification GO:0001708 52 33 0,000 0,11866459 0,1414101 ! sterol transport GO:0015918 57 33 0,000 0,11866459 0,1413401 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,11866459 0,14127016 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,11866459 0,1412003 ! adult locomotory behavior GO:0008344 59 33 0,000 0,11866459 0,1411305 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,11866459 0,14106077 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,11866459 0,14099111 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,12203361 0,14492244 ! glial cell differentiation GO:0010001 63 34 0,000 0,12203361 0,14485094 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12203361 0,14477952 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,12203361 0,14470816 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,12203361 0,14463688 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,12203361 0,14456566 ! mismatch repair GO:0006298 46 34 0,000 0,12203361 0,14449452 ! spermatid development GO:0007286 63 34 0,000 0,12203361 0,14442344 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,12203361 0,14435244 ! placenta development GO:0001890 53 34 0,000 0,12203361 0,1442815 ! regulation of muscle development GO:0048634 70 35 0,000 0,12538986 0,14817682 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,12538986 0,14810407 ! negative regulation of secretion GO:0051048 63 35 0,000 0,12538986 0,1480314 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,12538986 0,1479588 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,12538986 0,14788627 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,12538986 0,14781382 ! odontogenesis GO:0042476 66 35 0,000 0,12538986 0,14774143 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,12538986 0,14766911 ! female gonad development GO:0008585 58 35 0,000 0,12538986 0,14759687 ! telencephalon development GO:0021537 68 35 0,000 0,12538986 0,14752469 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,12538986 0,14745259 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,12538986 0,14738056 ! cytokine production GO:0001816 59 35 0,000 0,12538986 0,14730859 ! neural tube formation GO:0001841 67 35 0,000 0,12538986 0,1472367 ! vesicle localization GO:0051648 64 35 0,000 0,12538986 0,14716488 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,12873339 0,15101538 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,12873339 0,15094178 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,12873339 0,15086826 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,12873339 0,15079481 ! cell junction organization GO:0034330 86 36 0,000 0,12873339 0,15072143 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,12873339 0,15064812 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,12873339 0,15057489 ! positive regulation of cell development GO:0010720 80 36 0,000 0,12873339 0,15050172 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,12873339 0,15042863 ! regulation of proteolysis GO:0030162 72 36 0,000 0,12873339 0,1503556 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,12873339 0,15028265 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,12873339 0,15020977 ! aerobic respiration GO:0009060 55 36 0,000 0,12873339 0,15013696 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,12873339 0,15006422 ! embryonic organ development GO:0048568 57 36 0,000 0,12873339 0,14999155 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,12873339 0,14991895 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,12873339 0,14984642 ! RNA export from nucleus GO:0006405 56 37 0,000 0,13206425 0,15364922 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,13206425 0,15357496 ! meiosis I GO:0007127 65 37 0,000 0,13206425 0,15350077 ! sister chromatid segregation GO:0000819 58 37 0,000 0,13206425 0,15342665 ! actomyosin structure organization GO:0031032 62 37 0,000 0,13206425 0,1533526 ! organic anion transport GO:0015711 68 37 0,000 0,13206425 0,15327863 ! tissue remodeling GO:0048771 76 37 0,000 0,13206425 0,15320472 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,13206425 0,15313089 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,13206425 0,15305713 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13206425 0,15298344 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13206425 0,15290981 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,13206425 0,15283627 ! spermatid differentiation GO:0048515 66 37 0,000 0,13206425 0,15276279 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,13538249 0,15652584 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,13538249 0,15645066 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,13538249 0,15637555 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,13538249 0,15630052 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,13538249 0,15622555 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,13538249 0,15615066 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,13538249 0,15607584 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,13538249 0,15600109 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,13538249 0,15592641 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,13538249 0,15585181 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,13538249 0,15577727 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,13538249 0,15570281 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,13538249 0,15562842 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,13538249 0,1555541 ! mRNA catabolic process GO:0006402 71 39 0,000 0,13868815 0,15927623 ! mammary gland development GO:0030879 86 39 0,000 0,13868815 0,15920024 ! learning GO:0007612 77 39 0,000 0,13868815 0,15912432 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,13868815 0,15904847 ! ion transmembrane transport GO:0034220 66 39 0,000 0,13868815 0,1589727 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,13868815 0,158897 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,13868815 0,15882137 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,13868815 0,15874581 ! RNA modification GO:0009451 57 39 0,000 0,13868815 0,15867033 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,13868815 0,15859491 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,14198129 0,1622836 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,14198129 0,16220654 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14198129 0,16212956 ! feeding behavior GO:0007631 59 40 0,000 0,14198129 0,16205265 ! negative regulation of binding GO:0051100 72 40 0,000 0,14198129 0,16197581 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,14198129 0,16189904 ! mesenchymal cell development GO:0014031 87 40 0,000 0,14198129 0,16182235 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 0,000 0,14198129 0,16174573 ! cytokinesis GO:0000910 72 40 0,000 0,14198129 0,16166918 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,14526194 0,1653265 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,14526194 0,16524833 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,14526194 0,16517024 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,14526194 0,16509222 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,14526194 0,16501427 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,14526194 0,1649364 ! T cell differentiation GO:0030217 81 41 0,000 0,14526194 0,1648586 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,14526194 0,16478087 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,14526194 0,16470322 ! female gamete generation GO:0007292 61 41 0,000 0,14526194 0,16462564 ! polyol metabolic process GO:0019751 66 41 0,000 0,14526194 0,16454813 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,14526194 0,16447069 ! regulation of tube size GO:0035150 71 42 0,000 0,14853016 0,16809198 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,14853016 0,16801295 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,14853016 0,167934 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,14853016 0,16785512 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,14853016 0,16777632 ! neuron migration GO:0001764 79 42 0,000 0,14853016 0,16769759 ! regulation of protein secretion GO:0050708 71 42 0,000 0,14853016 0,16761893 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,15178598 0,17121288 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,15178598 0,17113265 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,15178598 0,1710525 ! glucose transport GO:0015758 65 43 0,000 0,15178598 0,17097241 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,15178598 0,17089241 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,15178598 0,17081248 ! neural tube development GO:0021915 77 43 0,000 0,15178598 0,17073262 ! striated muscle contraction GO:0006941 77 43 0,000 0,15178598 0,17065284 ! phagocytosis GO:0006909 90 43 0,000 0,15178598 0,17057313 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15178598 0,1704935 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,15502947 0,17405549 ! hexose transport GO:0008645 67 44 0,000 0,15502947 0,1739743 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,15502947 0,1738932 ! male sex differentiation GO:0046661 76 44 0,000 0,15502947 0,17381216 ! double-strand break repair GO:0006302 81 44 0,000 0,15502947 0,17373121 ! B cell differentiation GO:0030183 107 44 0,000 0,15502947 0,17365033 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,15502947 0,17356952 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,15502947 0,17348879 ! developmental growth GO:0048589 82 44 0,000 0,15502947 0,17340814 ! maintenance of location in cell GO:0051651 97 44 0,000 0,15502947 0,17332756 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,15826066 0,17685794 ! glycolysis GO:0006096 65 45 0,000 0,15826066 0,17677584 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,15826066 0,17669381 ! leukocyte migration GO:0050900 68 45 0,000 0,15826066 0,17661185 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,15826066 0,17652997 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,15826066 0,17644817 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,15826066 0,17636644 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,15826066 0,17628479 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,15826066 0,17620322 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,15826066 0,17612172 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,1614796 0,17962086 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,1614796 0,17953786 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,1614796 0,17945493 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,1614796 0,17937208 ! positive regulation of defense response GO:0031349 76 47 0,000 0,16468634 0,18284972 ! endosome transport GO:0016197 108 47 0,000 0,16468634 0,18276538 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,16468634 0,18268112 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,16468634 0,18259693 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,16468634 0,18251282 ! JNK cascade GO:0007254 91 47 0,000 0,16468634 0,18242879 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,16468634 0,18234484 ! protein homooligomerization GO:0051260 76 47 0,000 0,16468634 0,18226097 ! mitochondrial transport GO:0006839 82 48 0,000 0,16788092 0,18571104 ! Notch signaling pathway GO:0007219 96 48 0,000 0,16788092 0,18562569 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,16788092 0,18554042 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,16788092 0,18545524 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,16788092 0,18537013 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,16788092 0,18528509 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,16788092 0,18520014 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,16788092 0,18511526 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,17106339 0,18853803 ! regulation of action potential GO:0001508 95 49 0,000 0,17106339 0,18845171 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,17106339 0,18836546 ! regulation of ion transport GO:0043269 77 49 0,000 0,17106339 0,18827929 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,17106339 0,1881932 ! response to temperature stimulus GO:0009266 76 49 0,000 0,17106339 0,18810719 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,17106339 0,18802125 ! endocrine system development GO:0035270 104 49 0,000 0,17106339 0,1879354 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,17106339 0,18784962 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,17106339 0,18776393 ! neuromuscular process GO:0050905 99 50 0,000 0,1742338 0,19115664 ! inner ear development GO:0048839 79 50 0,000 0,1742338 0,19106952 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,1742338 0,19098247 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,1742338 0,1908955 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,17739218 0,19426745 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,17739218 0,19417907 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,17739218 0,19409076 ! excretion GO:0007588 83 51 0,000 0,17739218 0,19400254 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,17739218 0,1939144 ! chromatin remodeling GO:0006338 109 51 0,000 0,17739218 0,19382633 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,17739218 0,19373835 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,17739218 0,19365045 ! vesicle organization GO:0016050 107 51 0,000 0,17739218 0,19356263 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,17739218 0,19347488 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,17739218 0,19338722 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,18053859 0,19672819 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,18053859 0,19663913 ! membrane fusion GO:0006944 110 52 0,000 0,18053859 0,19655016 ! positive regulation of growth GO:0045927 90 52 0,000 0,18053859 0,19646126 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,18053859 0,19637244 ! cartilage development GO:0051216 90 52 0,000 0,18053859 0,19628371 ! synapse organization GO:0050808 85 52 0,000 0,18053859 0,19619505 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,18367307 0,19951124 ! RNA catabolic process GO:0006401 93 53 0,000 0,18367307 0,19942121 ! regulation of translational initiation GO:0006446 82 53 0,000 0,18367307 0,19933126 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,18367307 0,19924139 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,18367307 0,1991516 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,18367307 0,19906189 ! cell maturation GO:0048469 100 53 0,000 0,18367307 0,19897226 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,18367307 0,19888272 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,18367307 0,19879325 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,18679566 0,20208199 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,18679566 0,20199117 ! cell recognition GO:0008037 85 54 0,000 0,18679566 0,20190043 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,18679566 0,20180977 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,18679566 0,20171919 ! chloride transport GO:0006821 90 55 0,000 0,18990641 0,20498646 ! glucose catabolic process GO:0006007 82 55 0,000 0,18990641 0,20489454 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,18990641 0,2048027 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,18990641 0,20471094 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,18990641 0,20461927 ! gastrulation GO:0007369 112 55 0,000 0,18990641 0,20452767 ! heart morphogenesis GO:0003007 97 55 0,000 0,18990641 0,20443616 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,18990641 0,20434473 ! RNA elongation GO:0006354 79 55 0,000 0,18990641 0,20425338 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,18990641 0,20416212 ! regulation of actin filament length GO:0030832 105 56 0,000 0,19300536 0,20740103 ! sensory perception of smell GO:0007608 80 56 0,000 0,19300536 0,20730844 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,19300536 0,20721593 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,19300536 0,20712351 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,19300536 0,20703117 ! proton transport GO:0015992 94 56 0,000 0,19300536 0,20693891 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,19300536 0,20684673 ! muscle fiber development GO:0048747 112 57 0,000 0,19609257 0,21006176 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,19609257 0,20996827 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,19609257 0,20987487 ! hydrogen transport GO:0006818 97 58 0,000 0,19916806 0,21307174 ! adult behavior GO:0030534 99 58 0,000 0,19916806 0,21297705 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,19916806 0,21288243 ! positive regulation of secretion GO:0051047 95 59 0,000 0,20223189 0,21606125 ! regulation of cellular component size GO:0032535 109 59 0,000 0,20223189 0,21596535 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,20223189 0,21586953 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,20223189 0,2157738 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,20223189 0,21567816 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,2052841 0,21883631 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,2052841 0,21873939 ! regulation of heart contraction GO:0008016 110 60 0,000 0,2052841 0,21864256 ! camera-type eye development GO:0043010 116 60 0,000 0,2052841 0,21854582 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,2052841 0,21844916 ! kidney development GO:0001822 122 60 0,000 0,2052841 0,21835258 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,20832473 0,22148887 ! mesoderm development GO:0007498 119 61 0,000 0,20832473 0,22139104 ! tRNA processing GO:0008033 89 61 0,000 0,20832473 0,22129329 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,20832473 0,22119564 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,21135383 0,22431289 ! gonad development GO:0008406 98 62 0,000 0,21135383 0,22421399 ! regulation of mitosis GO:0007088 105 63 0,000 0,21437145 0,22731498 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,21437145 0,22721485 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,21437145 0,2271148 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,21737761 0,2301983 ! cell redox homeostasis GO:0045454 102 64 0,000 0,21737761 0,23009702 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,21737761 0,22999584 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,21737761 0,22989474 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,21737761 0,22979373 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,21737761 0,22969281 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,22037237 0,23275502 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,22037237 0,23265289 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,22037237 0,23255085 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,22037237 0,23244889 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,22335577 0,23549255 ! actin filament organization GO:0007015 148 66 0,000 0,22335577 0,2353894 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,22335577 0,23528634 ! extracellular matrix organization GO:0030198 133 66 0,000 0,22335577 0,23518337 ! secondary metabolic process GO:0019748 116 66 0,000 0,22335577 0,23508049 ! developmental maturation GO:0021700 116 66 0,000 0,22335577 0,2349777 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,22632786 0,23800036 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,22632786 0,23789639 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,22632786 0,2377925 ! activation of MAPK activity GO:0000187 115 67 0,000 0,22632786 0,23768871 ! chromosome segregation GO:0007059 113 67 0,000 0,22632786 0,237585 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,22632786 0,23748139 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,22632786 0,23737787 ! hexose catabolic process GO:0019320 104 67 0,000 0,22632786 0,23727443 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,22632786 0,23717109 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,22632786 0,23706784 ! adaptive immune response GO:0002250 119 67 0,000 0,22632786 0,23696468 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,22632786 0,2368616 ! amino acid transport GO:0006865 125 68 0,000 0,22928867 0,23985588 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,22928867 0,23975164 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,22928867 0,23964749 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,22928867 0,23954344 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,22928867 0,23943947 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,22928867 0,23933559 ! negative regulation of cell size GO:0045792 134 69 0,000 0,23223824 0,24230928 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,23223824 0,24220425 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,23223824 0,24209931 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,23223824 0,24199446 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,23223824 0,2418897 ! appendage morphogenesis GO:0035107 135 70 0,000 0,23517663 0,24484421 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,23810386 0,24778456 ! appendage development GO:0048736 136 71 0,000 0,23810386 0,24767743 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,23810386 0,2475704 ! B cell activation GO:0042113 160 71 0,000 0,23810386 0,24746345 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,23810386 0,24735661 ! regulation of immune effector process GO:0002697 137 71 0,000 0,23810386 0,24724985 ! acute inflammatory response GO:0002526 113 72 0,000 0,24101999 0,25017002 ! carbohydrate transport GO:0008643 110 72 0,000 0,24101999 0,25006214 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,24101999 0,24995436 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,24101999 0,24984666 ! learning or memory GO:0007611 147 73 0,000 0,24392506 0,25274922 ! regulation of blood pressure GO:0008217 125 73 0,000 0,24392506 0,25264042 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,24392506 0,25253171 ! axon guidance GO:0007411 139 73 0,000 0,24392506 0,2524231 ! fertilization GO:0009566 90 73 0,000 0,24392506 0,25231457 ! transition metal ion transport GO:0000041 126 74 0,000 0,2468191 0,25519844 ! neurotransmitter transport GO:0006836 123 74 0,000 0,2468191 0,25508882 ! meiosis GO:0007126 121 74 0,000 0,2468191 0,25497929 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,2468191 0,25486986 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,2468191 0,25476052 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,2468191 0,25465127 ! eye development GO:0001654 143 74 0,000 0,2468191 0,25454212 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,24970216 0,25740506 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,24970216 0,25729482 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,24970216 0,25718468 ! meiotic cell cycle GO:0051321 122 75 0,000 0,24970216 0,25707463 ! rhythmic process GO:0048511 128 75 0,000 0,24970216 0,25696467 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,24970216 0,25685481 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,25257429 0,25969818 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,25257429 0,25958724 ! defense response to bacterium GO:0042742 89 76 0,000 0,25257429 0,2594764 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,25257429 0,25936566 ! regulation of catabolic process GO:0009894 161 76 0,000 0,25257429 0,259255 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,25543551 0,2620801 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,25543551 0,26196838 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,25543551 0,26185677 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,25543551 0,26174524 ! blood coagulation GO:0007596 146 78 0,000 0,25828587 0,26455334 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,25828587 0,26444077 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,25828587 0,26432829 ! protein oligomerization GO:0051259 139 78 0,000 0,25828587 0,2642159 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,26112542 0,26700712 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,26112542 0,26689369 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,26112542 0,26678036 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,26112542 0,26666713 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,26395419 0,26944157 ! muscle cell differentiation GO:0042692 159 80 0,000 0,26395419 0,2693273 ! inorganic anion transport GO:0015698 138 80 0,000 0,26395419 0,26921313 ! T cell activation GO:0042110 168 81 0,000 0,26677222 0,27197202 ! digestion GO:0007586 112 81 0,000 0,26677222 0,27185682 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,26677222 0,27174173 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,26957956 0,27448515 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,26957956 0,27436904 ! response to nutrient GO:0007584 125 82 0,000 0,26957956 0,27425303 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,26957956 0,27413711 ! regulation of lyase activity GO:0051339 160 83 0,000 0,27237624 0,27686406 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,27516231 0,27957792 ! hemostasis GO:0007599 158 84 0,000 0,27516231 0,2794599 ! negative regulation of transport GO:0051051 153 84 0,000 0,27516231 0,27934199 ! negative regulation of growth GO:0045926 155 84 0,000 0,27516231 0,27922417 ! regulation of ligase activity GO:0051340 142 84 0,000 0,27516231 0,27910645 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,2779378 0,28180292 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,28070275 0,28448645 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,28070275 0,28436666 ! tube morphogenesis GO:0035239 176 86 0,000 0,28070275 0,28424698 ! alcohol catabolic process GO:0046164 130 86 0,000 0,28070275 0,2841274 ! amine transport GO:0015837 155 86 0,000 0,28070275 0,28400792 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,28345721 0,28667426 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,28345721 0,2865538 ! cellular respiration GO:0045333 135 88 0,000 0,28620122 0,28920627 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,28620122 0,28908486 ! ossification GO:0001503 188 90 0,000 0,29165801 0,29447301 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,29165801 0,29434949 ! bone development GO:0060348 189 91 0,000 0,29437088 0,29696283 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,29437088 0,29683836 ! regulation of defense response GO:0031347 149 92 0,000 0,29707345 0,29943809 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,29707345 0,2993127 ! vitamin metabolic process GO:0006766 139 92 0,000 0,29707345 0,29918741 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,29976576 0,30177256 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,29976576 0,30164635 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,29976576 0,30152024 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,29976576 0,30139424 ! regulation of membrane potential GO:0042391 164 93 0,000 0,29976576 0,30126834 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,29976576 0,30114255 ! female pregnancy GO:0007565 164 94 0,000 0,30244784 0,30371015 ! regulation of T cell activation GO:0050863 158 94 0,000 0,30244784 0,30358344 ! forebrain development GO:0030900 188 95 0,000 0,30511974 0,30613766 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,3077815 0,30867957 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,3077815 0,30855095 ! protein ubiquitination GO:0016567 217 97 0,000 0,31043315 0,31107962 ! hormone metabolic process GO:0042445 157 97 0,000 0,31043315 0,31095011 ! response to virus GO:0009615 160 98 0,000 0,31307473 0,31346558 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,31307473 0,31333519 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,31570627 0,31583754 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,31570627 0,31570627