pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1169-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 13 6 2,000 7,831E-07 1,913E-03 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 7,831E-07 9,566E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 17 8 2,000 2,182E-06 1,777E-03 ! establishment of nucleus localization GO:0040023 18 8 2,000 2,182E-06 1,332E-03 ! macrophage differentiation GO:0030225 15 9 2,000 3,264E-06 1,595E-03 ! protein sumoylation GO:0016925 17 10 2,000 4,652E-06 1,894E-03 ! nucleus localization GO:0051647 22 11 2,000 6,38E-06 2,227E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 8,485E-06 2,591E-03 ! filopodium assembly GO:0046847 42 17 2,000 2,59E-05 7,03E-03 ! microspike assembly GO:0030035 46 18 2,000 3,1E-05 7,574E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 8,586E-05 0,01906938 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 9,682E-05 0,01971083 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 1,086E-04 0,02041771 ! protein maturation by protein folding GO:0022417 14 5 1,000 1,161E-04 0,0202528 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 1,161E-04 0,01890261 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 1,161E-04 0,0177212 ! sequestering of calcium ion GO:0051208 7 5 1,000 1,161E-04 0,01667878 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 1,35E-04 0,01832925 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 1,497E-04 0,01924568 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,737E-04 0,02121761 ! triglyceride catabolic process GO:0019433 10 6 1,000 1,737E-04 0,02020725 ! response to drug GO:0042493 149 83 3,000 1,969E-04 0,02186275 ! prostate gland development GO:0030850 14 7 1,000 2,426E-04 0,02577206 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,426E-04 0,02469822 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 2,426E-04 0,02371029 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 2,426E-04 0,02279836 GO:0031958|corticosteroid receptor signaling pathway, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,426E-04 0,02195398 ! glycerol ether catabolic process GO:0044269 12 7 1,000 2,426E-04 0,02116991 GO:0046464|acylglycerol catabolic process, ! regulation of meiosis GO:0040020 12 7 1,000 2,426E-04 0,02043991 GO:0051445|regulation of meiotic cell cycle, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,228E-04 0,02628555 ! oligopeptide transport GO:0006857 16 8 1,000 3,228E-04 0,02543763 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 3,228E-04 0,0246427 ! glycerolipid catabolic process GO:0046503 14 8 1,000 3,228E-04 0,02389596 ! ER overload response GO:0006983 13 8 1,000 3,228E-04 0,02319313 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 3,228E-04 0,02253047 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 3,823E-04 0,0259454 ! neutral lipid catabolic process GO:0046461 14 9 1,000 4,141E-04 0,02734034 ! microtubule bundle formation GO:0001578 22 9 1,000 4,141E-04 0,02662086 ! middle ear morphogenesis GO:0042474 14 9 1,000 4,141E-04 0,02593828 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 4,141E-04 0,02528982 ! regulation of telomere maintenance GO:0032204 17 9 1,000 4,141E-04 0,02467299 ! CTP metabolic process GO:0046036 11 10 1,000 5,164E-04 0,03003928 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of phagocytosis GO:0050766 14 10 1,000 5,164E-04 0,0293407 ! pigmentation GO:0043473 103 46 2,000 5,377E-04 0,02985364 ! positive regulation of cell cycle GO:0045787 96 48 2,000 6,096E-04 0,03309341 ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 6,298E-04 0,0334468 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 6,298E-04 0,03273517 ! detection of mechanical stimulus GO:0050982 22 11 1,000 6,298E-04 0,03205319 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 6,298E-04 0,03139904 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 1,000 6,298E-04 0,03077106 ! DNA methylation GO:0006306 19 11 1,000 6,298E-04 0,03016771 GO:0006305|DNA alkylation, ! apical protein localization GO:0045176 18 11 1,000 6,298E-04 0,02958756 ! sequestering of metal ion GO:0051238 15 11 1,000 6,298E-04 0,0290293 ! regulation of cell projection organization GO:0031344 135 51 2,000 7,285E-04 0,03295687 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 7,54E-04 0,03349305 ! entry into host cell GO:0030260 34 12 1,000 7,54E-04 0,03289496 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 17 12 1,000 7,54E-04 0,03231785 ! histone acetylation GO:0016573 27 12 1,000 7,54E-04 0,03176065 ! peptidyl-lysine modification GO:0018205 21 12 1,000 7,54E-04 0,03122233 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 8,891E-04 0,03620268 ! asymmetric protein localization GO:0008105 24 13 1,000 8,891E-04 0,03560919 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 1,000 8,891E-04 0,03503485 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 8,891E-04 0,03447874 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 1,008E-03 0,03848986 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,035E-03 0,0389 ! aging GO:0007568 112 58 2,000 1,061E-03 0,03926128 ! establishment of organelle localization GO:0051656 122 59 2,000 1,115E-03 0,04064569 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,192E-03 0,04280814 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 1,000 1,192E-03 0,04218773 ! dopamine metabolic process GO:0042417 35 15 1,000 1,192E-03 0,04158505 ! regulation of homeostatic process GO:0032844 148 62 2,000 1,287E-03 0,0442895 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,348E-03 0,04574394 ! regulation of neurotransmitter secretion GO:0046928 35 16 1,000 1,359E-03 0,04547043 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 1,000 1,359E-03 0,04485597 ! DNA replication initiation GO:0006270 28 16 1,000 1,359E-03 0,04425789 ! regulation of survival gene product expression GO:0045884 38 17 1,000 1,536E-03 0,04938794 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 1,536E-03 0,04874654 GO:0031114|regulation of microtubule depolymerization, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 1,536E-03 0,04812159 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 1,542E-03 0,04768349 ! myeloid cell differentiation GO:0030099 126 67 2,000 1,61E-03 0,04917204 ! cell projection assembly GO:0030031 138 68 2,000 1,68E-03 0,05068007 ! glutamine metabolic process GO:0006541 29 18 1,000 1,725E-03 0,05138051 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 1,000 1,725E-03 0,05076147 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 1,725E-03 0,05015717 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 1,923E-03 0,05527433 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 1,923E-03 0,05463161 ! protein export from nucleus GO:0006611 40 19 1,000 1,923E-03 0,05400366 ! cellular pigmentation GO:0033059 37 19 1,000 1,923E-03 0,05338998 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,132E-03 0,05852422 ! protein amino acid acetylation GO:0006473 41 20 1,000 2,132E-03 0,05787395 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 2,132E-03 0,05723798 ! response to alkaloid GO:0043279 38 20 1,000 2,132E-03 0,05661582 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 2,132E-03 0,05600705 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,132E-03 0,05541123 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 2,132E-03 0,05482796 ! negative regulation of translation GO:0017148 32 20 1,000 2,132E-03 0,05425683 ! organelle localization GO:0051640 155 74 2,000 2,141E-03 0,05392922 ! lipid phosphorylation GO:0046834 43 21 1,000 2,351E-03 0,05861264 ! regulation of neurotransmitter transport GO:0051588 44 21 1,000 2,351E-03 0,05802059 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 2,351E-03 0,05744038 ! apoptotic nuclear changes GO:0030262 34 22 1,000 2,581E-03 0,06241872 ! cell aging GO:0007569 48 22 1,000 2,581E-03 0,06180678 ! G1 phase GO:0051318 44 22 1,000 2,581E-03 0,06120671 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 2,581E-03 0,06061818 ! peptidyl-serine modification GO:0018209 50 22 1,000 2,581E-03 0,06004087 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 1,000 2,581E-03 0,05947445 ! protein stabilization GO:0050821 41 22 1,000 2,581E-03 0,05891861 ! positive regulation of DNA replication GO:0045740 44 23 1,000 2,82E-03 0,06378926 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 2,82E-03 0,06320404 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 2,82E-03 0,06262945 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 2,82E-03 0,06206522 ! DNA modification GO:0006304 36 23 1,000 2,82E-03 0,06151107 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 3,069E-03 0,06636028 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 3,069E-03 0,06577817 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 3,069E-03 0,06520619 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 1,000 3,069E-03 0,06464406 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 3,069E-03 0,06409155 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 3,329E-03 0,06891977 ! interaction with host GO:0051701 66 25 1,000 3,329E-03 0,06834061 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 3,598E-03 0,07325444 ! initiation of viral infection GO:0019059 60 26 1,000 3,598E-03 0,07264903 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 3,598E-03 0,07205355 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 3,877E-03 0,07701253 ! cellular response to oxidative stress GO:0034599 43 27 1,000 3,877E-03 0,07639146 ! regulation of chromosome organization GO:0033044 49 27 1,000 3,877E-03 0,07578033 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 4,166E-03 0,08078086 ! protein amino acid acylation GO:0043543 59 28 1,000 4,166E-03 0,08014479 ! dendrite development GO:0016358 67 28 1,000 4,166E-03 0,07951865 ! fat cell differentiation GO:0045444 57 28 1,000 4,166E-03 0,07890223 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 4,166E-03 0,07829529 ! glutathione metabolic process GO:0006749 42 28 1,000 4,166E-03 0,07769762 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 4,465E-03 0,08263563 ! catechol metabolic process GO:0009712 55 29 1,000 4,465E-03 0,08201431 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! somitogenesis GO:0001756 52 29 1,000 4,465E-03 0,08140226 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 4,465E-03 0,08079928 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 4,6E-03 0,0826286 ! leukocyte differentiation GO:0002521 232 98 2,000 4,733E-03 0,08440627 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 4,733E-03 0,08379463 ! phenol metabolic process GO:0018958 56 30 1,000 4,773E-03 0,08389151 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 4,773E-03 0,08329229 ! sterol biosynthetic process GO:0016126 56 30 1,000 4,773E-03 0,08270156 ! peptide transport GO:0015833 60 31 1,000 5,091E-03 0,08758642 ! iron ion homeostasis GO:0055072 60 31 1,000 5,091E-03 0,08697392 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 5,091E-03 0,08636994 ! response to mechanical stimulus GO:0009612 60 32 1,000 5,418E-03 0,0912882 ! triglyceride metabolic process GO:0006641 46 33 1,000 5,755E-03 0,09629664 ! regulation of ARF GTPase activity GO:0032312 73 34 1,000 6,101E-03 0,1013923 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 6,101E-03 0,10070721 ! positive regulation of endocytosis GO:0045807 56 35 1,000 6,456E-03 0,10585704 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 6,821E-03 0,11108828 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 1,000 6,821E-03 0,11035259 ! regulation of microtubule-based process GO:0032886 86 37 1,000 7,194E-03 0,11563245 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 7,577E-03 0,1209883 ! neutral lipid metabolic process GO:0006638 54 38 1,000 7,577E-03 0,12020266 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 77 38 1,000 7,577E-03 0,11942716 ! glycogen metabolic process GO:0005977 63 38 1,000 7,577E-03 0,1186616 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 7,577E-03 0,11790579 ! glucan metabolic process GO:0044042 64 39 1,000 7,969E-03 0,12321718 GO:0006073|cellular glucan metabolic process, ! nucleus organization GO:0006997 73 40 1,000 8,37E-03 0,12859928 ! glycerol ether metabolic process GO:0006662 57 40 1,000 8,37E-03 0,12779553 ! gliogenesis GO:0042063 91 41 1,000 8,779E-03 0,13321717 ! ear morphogenesis GO:0042471 64 42 1,000 9,198E-03 0,1387049 ! organic ether metabolic process GO:0018904 59 42 1,000 9,198E-03 0,13785395 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 9,198E-03 0,13701338 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 9,198E-03 0,136183 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 9,625E-03 0,1416495 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 9,625E-03 0,1408013 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 9,625E-03 0,1399632 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,01006086 0,14543595 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 0,01006086 0,14458045 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,01006086 0,14373495 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,01006086 0,14289928 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,01050537 0,14835038 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 0,01050537 0,14749779 ! biopolymer methylation GO:0043414 91 45 1,000 0,01050537 0,14665495 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 0,01095845 0,1521107 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01095845 0,15125131 ! cell growth GO:0016049 90 46 1,000 0,01095845 0,15040159 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01095845 0,14956135 ! response to insulin stimulus GO:0032868 98 47 1,000 0,01142002 0,15499511 ! cellular component disassembly GO:0022411 89 48 1,000 0,01189004 0,16048275 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01189004 0,15960098 ! methylation GO:0032259 97 48 1,000 0,01189004 0,15872884 ! response to calcium ion GO:0051592 94 49 1,000 0,01236844 0,16421794 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,01236844 0,16333028 ! regulation of ARF protein signal transduction GO:0032012 115 50 1,000 0,01285515 0,16884484 ! activation of caspase activity GO:0006919 95 50 1,000 0,01285515 0,16794193 ! regulation of ossification GO:0030278 123 50 1,000 0,01285515 0,16704862 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01285515 0,16616476 ! viral infectious cycle GO:0019058 104 51 1,000 0,01335012 0,17165444 ! peptide metabolic process GO:0006518 80 51 1,000 0,01335012 0,17075572 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,01335012 0,16986637 ! positive regulation of binding GO:0051099 88 52 1,000 0,01385328 0,17535523 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,01385328 0,17445134 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,01385328 0,17355672 ! histone modification GO:0016570 104 52 1,000 0,01385328 0,17267123 ! amino acid activation GO:0043038 98 52 1,000 0,01385328 0,17179472 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! covalent chromatin modification GO:0016569 115 54 1,000 0,01488393 0,18364364 ! glutamine family amino acid metabolic process GO:0009064 85 54 1,000 0,01488393 0,1827208 ! regulation of cell shape GO:0008360 142 54 1,000 0,01488393 0,1818072 ! response to UV GO:0009411 120 55 1,000 0,0154113 0,18731247 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,01594662 0,19285938 ! regulation of DNA replication GO:0006275 105 56 1,000 0,01594662 0,19190933 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01648983 0,19747381 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,01648983 0,19651053 GO:0010952|positive regulation of peptidase activity, ! regulation of intracellular transport GO:0032386 108 57 1,000 0,01648983 0,19555659 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01704087 0,20111522 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01704087 0,20014832 ! maintenance of location GO:0051235 124 58 1,000 0,01704087 0,19919067 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01704537 0,1982945 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01704537 0,19735472 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01704537 0,1964238 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01704537 0,19550162 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01704537 0,19458806 ! neuron fate determination GO:0048664 7 5 0,000 0,01704537 0,193683 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01704537 0,19278632 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01704537 0,1918979 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01704537 0,19101764 ! polyol transport GO:0015791 12 5 0,000 0,01704537 0,19014541 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01704537 0,18928111 ! response to superoxide GO:0000303 10 5 0,000 0,01704537 0,18842464 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01704537 0,18757588 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01704537 0,18673473 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01704537 0,18590109 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01704537 0,18507487 ! female meiosis GO:0007143 10 5 0,000 0,01704537 0,18425595 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01704537 0,18344425 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01704537 0,18263967 ! hypothalamus development GO:0021854 9 5 0,000 0,01704537 0,18184212 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01704537 0,1810515 ! cobalt ion transport GO:0006824 11 5 0,000 0,01704537 0,18026773 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01704537 0,17949071 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01704537 0,17872036 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01704537 0,1779566 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01704537 0,17719934 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01704537 0,1764485 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01704537 0,17570399 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01704537 0,17496574 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01704537 0,17423366 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01704537 0,17350769 ! transposition GO:0032196 9 5 0,000 0,01704537 0,17278774 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01704537 0,17207374 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01704537 0,17136562 ! negative chemotaxis GO:0050919 16 5 0,000 0,01704537 0,1706633 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01704537 0,16996671 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01704537 0,16927579 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01704537 0,16859047 ! behavioral response to pain GO:0048266 10 5 0,000 0,01704537 0,16791067 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01704537 0,16723633 ! Notch receptor processing GO:0007220 11 5 0,000 0,01704537 0,16656738 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01704537 0,16590376 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01704537 0,16524542 ! micturition GO:0060073 9 5 0,000 0,01704537 0,16459227 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01704537 0,16394427 ! copulation GO:0007620 9 5 0,000 0,01704537 0,16330135 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01704537 0,16266346 ! bioluminescence GO:0008218 9 5 0,000 0,01704537 0,16203053 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01704537 0,1614025 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01704537 0,16077932 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01704537 0,16016094 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01704537 0,1595473 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01704537 0,15893834 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01704537 0,15833401 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01704537 0,15773426 ! grooming behavior GO:0007625 6 5 0,000 0,01704537 0,15713904 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01704537 0,15654829 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01704537 0,15596197 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01704537 0,15538002 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01704537 0,1548024 ! response to protozoan GO:0001562 13 5 0,000 0,01704537 0,15422906 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01704537 0,15365994 ! lymph vessel development GO:0001945 10 5 0,000 0,01704537 0,15309502 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01704537 0,15253423 ! endochondral ossification GO:0001958 17 5 0,000 0,01704537 0,15197754 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01704537 0,15142489 ! single strand break repair GO:0000012 8 5 0,000 0,01704537 0,15087625 ! parathyroid gland development GO:0060017 14 5 0,000 0,01704537 0,15033157 ! anagen GO:0042640 7 5 0,000 0,01704537 0,14979081 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01704537 0,14925392 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01704537 0,14872088 ! cytokine secretion GO:0050663 15 5 0,000 0,01704537 0,14819162 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01704537 0,14766612 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01704537 0,14714433 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01704537 0,14662621 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01704537 0,14611174 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01704537 0,14560086 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01704537 0,14509354 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01704537 0,14458974 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01704537 0,14408943 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01704537 0,14359257 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01704537 0,14309912 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01704537 0,14260906 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01704537 0,14212234 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01704537 0,14163893 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01704537 0,1411588 ! microvillus organization GO:0032528 8 5 0,000 0,01704537 0,14068191 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01704537 0,14020823 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01704537 0,13973773 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01704537 0,13927038 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01704537 0,13880615 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01704537 0,138345 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01704537 0,1378869 ! polyol catabolic process GO:0046174 9 5 0,000 0,01704537 0,13743183 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01704537 0,13697975 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01704537 0,13653064 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01704537 0,13608446 ! muscle cell migration GO:0014812 8 5 0,000 0,01704537 0,13564119 ! mitochondrial fission GO:0000266 8 5 0,000 0,01704537 0,1352008 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01704537 0,13476325 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01704537 0,13432853 ! mRNA transcription GO:0009299 10 5 0,000 0,01704537 0,13389661 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01704537 0,13346745 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01704537 0,13304104 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01704537 0,13261734 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01704537 0,13219633 ! monocyte activation GO:0042117 10 5 0,000 0,01704537 0,13177799 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01704537 0,13136229 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01704537 0,1309492 ! response to food GO:0032094 6 5 0,000 0,01704537 0,1305387 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01704537 0,13013077 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01704537 0,12972537 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01704537 0,1293225 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01704537 0,12892212 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01704537 0,12852421 ! forebrain neuron development GO:0021884 13 5 0,000 0,01704537 0,12812875 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01704537 0,12773572 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01704537 0,12734509 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01704537 0,12695684 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01704537 0,12657096 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01704537 0,12618741 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01704537 0,12580618 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01704537 0,12542724 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01704537 0,12505059 ! lipid glycosylation GO:0030259 7 5 0,000 0,01704537 0,12467618 ! nucleobase transport GO:0015851 6 5 0,000 0,01704537 0,12430401 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01704537 0,12393406 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01704537 0,12356631 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01704537 0,12320072 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01704537 0,1228373 ! basic amino acid transport GO:0015802 12 5 0,000 0,01704537 0,12247601 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01704537 0,12211685 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01704537 0,12175978 ! actin nucleation GO:0045010 11 5 0,000 0,01704537 0,1214048 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01704537 0,12105188 ! depurination GO:0045007 5 5 0,000 0,01704537 0,120701 ! depyrimidination GO:0045008 10 5 0,000 0,01704537 0,12035215 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01704537 0,12000532 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01704537 0,11966047 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01704537 0,11931761 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01704537 0,1189767 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01704537 0,11863774 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01704537 0,1183007 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01704537 0,11796557 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01704537 0,11763233 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01704537 0,11730097 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01704537 0,11697147 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01704537 0,11664382 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01704537 0,116318 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01704537 0,115994 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01704537 0,11567179 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01704537 0,11535137 ! response to arsenic GO:0046685 11 5 0,000 0,01704537 0,11503272 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01704537 0,11471583 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01704537 0,11440067 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01704537 0,11408725 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01704537 0,11377553 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01704537 0,11346552 ! response to mercury ion GO:0046689 8 5 0,000 0,01704537 0,11315719 ! response to cadmium ion GO:0046686 7 5 0,000 0,01704537 0,11285053 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01704537 0,11254553 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01704537 0,11224217 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01704537 0,11194044 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01704537 0,11164034 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01704537 0,11134183 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01704537 0,11104492 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01704537 0,11074959 ! decidualization GO:0046697 11 5 0,000 0,01704537 0,11045582 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01704537 0,11016361 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01704537 0,10987294 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01704537 0,1095838 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01704537 0,10929618 ! embryonic cleavage GO:0040016 6 5 0,000 0,01704537 0,10901007 ! peroxisome fission GO:0016559 5 5 0,000 0,01704537 0,10872544 ! histone demethylation GO:0016577 13 5 0,000 0,01704537 0,1084423 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01704537 0,10816064 ! mitotic recombination GO:0006312 9 5 0,000 0,01704537 0,10788043 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01704537 0,10760167 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01704537 0,10732434 ! metaphase plate congression GO:0051310 7 5 0,000 0,01704537 0,10704844 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01704537 0,10677396 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01704537 0,10650088 ! enteric nervous system development GO:0048484 8 5 0,000 0,01704537 0,1062292 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01704537 0,10595889 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01704537 0,10568996 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01704537 0,10542239 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01704537 0,10515617 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01704537 0,1048913 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01704537 0,10462775 ! B cell homeostasis GO:0001782 13 5 0,000 0,01704537 0,10436553 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01704537 0,10410461 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01704537 0,103845 ! metaphase GO:0051323 11 5 0,000 0,01704537 0,10358668 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01704537 0,10332964 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01704537 0,10307387 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01704537 0,10281937 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01704537 0,10256612 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01704537 0,10231412 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01704537 0,10206335 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01704537 0,1018138 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01704537 0,10156548 ! response to redox state GO:0051775 6 5 0,000 0,01704537 0,10131836 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01704537 0,10107244 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01704537 0,10082771 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01704537 0,10058417 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01704537 0,1003418 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01704537 0,10010059 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01704537 0,09986054 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01704537 0,09962164 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01704537 0,09938388 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01704537 0,09914725 ! striatum development GO:0021756 14 5 0,000 0,01704537 0,09891175 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01704537 0,09867736 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01704537 0,09844408 ! glial cell migration GO:0008347 10 5 0,000 0,01704537 0,0982119 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01704537 0,09798081 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01704537 0,09775081 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01704537 0,09752189 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01704537 0,09729403 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01704537 0,09706724 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01704537 0,0968415 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01704537 0,09661681 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01704537 0,09639316 ! neuroprotection GO:0043526 8 5 0,000 0,01704537 0,09617054 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01704537 0,09594895 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01704537 0,09572838 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01704537 0,09550882 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01704537 0,09529026 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01704537 0,09507271 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01704537 0,09485614 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01704537 0,09464056 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01704537 0,09442595 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01704537 0,09421232 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01704537 0,09399965 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01704537 0,09378794 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01704537 0,09357718 ! spindle assembly GO:0051225 6 5 0,000 0,01704537 0,09336737 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01704537 0,09315849 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01704537 0,09295055 ! protein palmitoylation GO:0018345 12 5 0,000 0,01704537 0,09274353 ! drug metabolic process GO:0017144 7 5 0,000 0,01704537 0,09253743 ! stem cell division GO:0017145 11 5 0,000 0,01704537 0,09233225 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01704537 0,09212798 ! organ regeneration GO:0031100 7 5 0,000 0,01704537 0,0919246 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01704537 0,09172213 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01704537 0,09152054 ! nuclear export GO:0051168 110 59 1,000 0,01759968 0,09428954 ! lipid modification GO:0030258 112 60 1,000 0,01816621 0,09711171 ! DNA catabolic process GO:0006308 94 60 1,000 0,01816621 0,09689967 ! regulation of endocytosis GO:0030100 104 60 1,000 0,01816621 0,09668856 ! viral reproductive process GO:0022415 132 62 1,000 0,01932216 0,10261748 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,01932216 0,10239488 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,01991147 0,10528946 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02041971 0,10774372 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02041971 0,10751152 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02041971 0,10728031 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02041971 0,10705009 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02041971 0,10682086 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02041971 0,10659261 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02041971 0,10636534 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02041971 0,10613903 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02041971 0,10591368 ! response to oxygen radical GO:0000305 11 6 0,000 0,02041971 0,10568929 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02041971 0,10546584 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02041971 0,10524334 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02041971 0,10502178 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02041971 0,10480114 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02041971 0,10458143 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02041971 0,10436264 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02041971 0,10414477 ! forebrain regionalization GO:0021871 9 6 0,000 0,02041971 0,1039278 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02041971 0,10371173 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02041971 0,10349656 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02041971 0,10328228 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02041971 0,10306889 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02041971 0,10285638 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02041971 0,10264474 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02041971 0,10243397 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02041971 0,10222406 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02041971 0,10201502 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02041971 0,10180682 ! malate metabolic process GO:0006108 13 6 0,000 0,02041971 0,10159948 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02041971 0,10139297 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02041971 0,10118731 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02041971 0,10098248 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02041971 0,10077847 ! protein refolding GO:0042026 15 6 0,000 0,02041971 0,10057529 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02041971 0,10037292 ! opsonization GO:0008228 8 6 0,000 0,02041971 0,10017137 ! mating behavior GO:0007617 7 6 0,000 0,02041971 0,09997063 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02041971 0,09977069 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02041971 0,09957154 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02041971 0,09937319 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02041971 0,09917563 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02041971 0,09897886 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02041971 0,09878286 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02041971 0,09858764 ! toxin metabolic process GO:0009404 11 6 0,000 0,02041971 0,09839318 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02041971 0,0981995 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02041971 0,09800657 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02041971 0,0978144 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02041971 0,09762298 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02041971 0,09743231 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02041971 0,09724239 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02041971 0,0970532 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02041971 0,09686474 ! thymic T cell selection GO:0045061 16 6 0,000 0,02041971 0,09667702 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02041971 0,09649003 ! protein lipoylation GO:0009249 10 6 0,000 0,02041971 0,09630375 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02041971 0,0961182 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02041971 0,09593335 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02041971 0,09574922 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02041971 0,09556579 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02041971 0,09538307 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02041971 0,09520104 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02041971 0,0950197 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02041971 0,09483906 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02041971 0,0946591 ! hyperosmotic response GO:0006972 10 6 0,000 0,02041971 0,09447982 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02041971 0,09430122 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02041971 0,09412329 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02041971 0,09394603 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02041971 0,09376944 ! urea metabolic process GO:0019627 7 6 0,000 0,02041971 0,09359352 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02041971 0,09341825 ! neutrophil activation GO:0042119 7 6 0,000 0,02041971 0,09324363 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02041971 0,09306967 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02041971 0,09289636 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02041971 0,09272369 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02041971 0,09255166 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02041971 0,09238027 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02041971 0,09220951 ! neuron apoptosis GO:0051402 15 6 0,000 0,02041971 0,09203938 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02041971 0,09186988 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02041971 0,091701 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02041971 0,09153274 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02041971 0,0913651 ! carnitine transport GO:0015879 10 6 0,000 0,02041971 0,09119807 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02041971 0,09103165 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02041971 0,09086584 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02041971 0,09070062 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02041971 0,09053601 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02041971 0,090372 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02041971 0,09020858 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02041971 0,09004575 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02041971 0,0898835 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02041971 0,08972184 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02041971 0,08956076 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02041971 0,08940026 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02041971 0,08924033 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02041971 0,08908097 ! response to UV-C GO:0010225 14 6 0,000 0,02041971 0,08892218 ! astrocyte development GO:0014002 16 6 0,000 0,02041971 0,08876396 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02041971 0,08860629 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02041971 0,08844919 ! interaction with symbiont GO:0051702 14 6 0,000 0,02041971 0,08829264 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02041971 0,08813665 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02041971 0,08798121 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02041971 0,08782631 ! response to copper ion GO:0046688 10 6 0,000 0,02041971 0,08767196 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02041971 0,08751815 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02041971 0,08736487 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02041971 0,08721214 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02041971 0,08705994 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02041971 0,08690826 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02041971 0,08675712 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02041971 0,0866065 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02041971 0,0864564 ! hair follicle maturation GO:0048820 8 6 0,000 0,02041971 0,08630682 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02041971 0,08615776 ! Schwann cell development GO:0014044 15 6 0,000 0,02041971 0,08600921 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02041971 0,08586118 ! response to pheromone GO:0019236 6 6 0,000 0,02041971 0,08571365 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02041971 0,08556663 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02041971 0,08542011 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02041971 0,08527409 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02041971 0,08512857 ! subpallium development GO:0021544 15 6 0,000 0,02041971 0,08498355 ! neural tube patterning GO:0021532 8 6 0,000 0,02041971 0,08483902 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02041971 0,08469498 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02041971 0,08455143 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02041971 0,08440836 ! G2 phase GO:0051319 16 6 0,000 0,02041971 0,08426578 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02041971 0,08412368 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02041971 0,08398206 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02041971 0,08384091 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02041971 0,08370024 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02041971 0,08356004 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02041971 0,08342031 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02041971 0,08328104 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02041971 0,08314224 ! receptor internalization GO:0031623 11 6 0,000 0,02041971 0,0830039 ! plasminogen activation GO:0031639 9 6 0,000 0,02041971 0,08286602 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02041971 0,0827286 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02041971 0,08259163 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02041971 0,08245511 ! protein deubiquitination GO:0016579 16 6 0,000 0,02041971 0,08231905 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02041971 0,08218343 ! protein destabilization GO:0031648 9 6 0,000 0,02041971 0,08204826 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02041971 0,08191354 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02041971 0,08177925 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02041971 0,08164541 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02041971 0,081512 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02041971 0,08137903 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02041971 0,08124649 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02041971 0,08111438 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02041971 0,0809827 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02041971 0,08085145 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02041971 0,08072062 ! neural plate development GO:0001840 9 6 0,000 0,02041971 0,08059022 ! catecholamine transport GO:0051937 9 6 0,000 0,02041971 0,08046023 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02041971 0,08033067 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02041971 0,08020152 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02041971 0,08007278 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02041971 0,07994446 ! maternal placenta development GO:0001893 12 6 0,000 0,02041971 0,07981655 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02041971 0,07968905 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02041971 0,07956195 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02041971 0,07943526 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02041971 0,07930897 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02041971 0,07918309 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02041971 0,0790576 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02041971 0,07893251 GO:0055081|anion homeostasis, ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,02050826 0,07914959 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,02050826 0,07902475 ! ear development GO:0043583 114 66 1,000 0,02172406 0,08357775 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,02172406 0,08344634 ! detection of external stimulus GO:0009581 102 68 1,000 0,02296908 0,08809022 ! viral reproduction GO:0016032 142 68 1,000 0,02296908 0,08795215 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,02360242 0,09023585 ! lung development GO:0030324 165 69 1,000 0,02360242 0,09009486 ! urogenital system development GO:0001655 149 69 1,000 0,02360242 0,0899543 ! tRNA transcription GO:0009304 17 7 0,000 0,02378255 0,09049965 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02378255 0,0903589 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02378255 0,09021859 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02378255 0,09007872 ! regulation of helicase activity GO:0051095 16 7 0,000 0,02378255 0,08993928 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02378255 0,08980027 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02378255 0,08966169 ! sleep GO:0030431 16 7 0,000 0,02378255 0,08952354 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02378255 0,08938581 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02378255 0,0892485 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02378255 0,08911162 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02378255 0,08897515 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02378255 0,0888391 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02378255 0,08870347 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02378255 0,08856825 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02378255 0,08843345 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02378255 0,08829905 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02378255 0,08816506 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02378255 0,08803148 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02378255 0,0878983 ! glycolipid transport GO:0046836 11 7 0,000 0,02378255 0,08776552 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02378255 0,08763314 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02378255 0,08750117 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02378255 0,08736959 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02378255 0,0872384 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02378255 0,08710761 ! mRNA stabilization GO:0048255 18 7 0,000 0,02378255 0,08697721 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02378255 0,0868472 ! fibril organization GO:0043206 17 7 0,000 0,02378255 0,08671757 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02378255 0,08658834 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02378255 0,08645949 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02378255 0,08633102 ! lipoprotein transport GO:0042953 14 7 0,000 0,02378255 0,08620293 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02378255 0,08607522 ! rhythmic behavior GO:0007622 17 7 0,000 0,02378255 0,08594789 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02378255 0,08582094 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02378255 0,08569436 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02378255 0,08556815 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02378255 0,08544232 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02378255 0,08531685 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02378255 0,08519175 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02378255 0,08506702 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02378255 0,08494265 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02378255 0,08481865 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02378255 0,08469501 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02378255 0,08457172 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02378255 0,0844488 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02378255 0,08432623 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02378255 0,08420402 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02378255 0,08408216 ! spinal cord patterning GO:0021511 14 7 0,000 0,02378255 0,08396066 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02378255 0,0838395 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02378255 0,0837187 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02378255 0,08359824 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02378255 0,08347812 ! adrenal gland development GO:0030325 17 7 0,000 0,02378255 0,08335836 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02378255 0,08323893 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02378255 0,08311985 ! ovulation GO:0030728 10 7 0,000 0,02378255 0,08300111 ! adenohypophysis development GO:0021984 11 7 0,000 0,02378255 0,0828827 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02378255 0,08276464 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02378255 0,08264691 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02378255 0,08252951 ! microtubule nucleation GO:0007020 21 7 0,000 0,02378255 0,08241245 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02378255 0,08229571 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02378255 0,08217931 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02378255 0,08206324 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02378255 0,0819475 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02378255 0,08183208 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02378255 0,08171698 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02378255 0,08160221 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02378255 0,08148776 ! galactose metabolic process GO:0006012 13 7 0,000 0,02378255 0,08137363 ! vesicle fusion GO:0006906 20 7 0,000 0,02378255 0,08125982 ! response to dietary excess GO:0002021 8 7 0,000 0,02378255 0,08114633 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02378255 0,08103316 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02378255 0,0809203 GO:0045851|pH reduction, ! melanosome organization GO:0032438 10 7 0,000 0,02378255 0,08080775 ! organ growth GO:0035265 15 7 0,000 0,02378255 0,08069552 ! nucleoside transport GO:0015858 11 7 0,000 0,02378255 0,0805836 ! nucleoside salvage GO:0043174 11 7 0,000 0,02378255 0,08047199 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02378255 0,08036068 ! male sex determination GO:0030238 15 7 0,000 0,02378255 0,08024969 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02378255 0,080139 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02378255 0,08002862 ! parturition GO:0007567 16 7 0,000 0,02378255 0,07991853 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02378255 0,07980876 ! rRNA modification GO:0000154 14 7 0,000 0,02378255 0,07969928 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02378255 0,0795901 ! spindle checkpoint GO:0031577 16 7 0,000 0,02378255 0,07948122 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02378255 0,07937264 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02378255 0,07926436 ! monocyte differentiation GO:0030224 16 7 0,000 0,02378255 0,07915637 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02378255 0,07904867 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02378255 0,07894127 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02378255 0,07883416 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02378255 0,07872734 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,02378255 0,0786208 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02378255 0,07851456 ! fibrinolysis GO:0042730 11 7 0,000 0,02378255 0,0784086 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02378255 0,07830293 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02378255 0,07819754 ! eating behavior GO:0042755 8 7 0,000 0,02378255 0,07809244 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02378255 0,07798762 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02378255 0,07788308 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02378255 0,07777881 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02378255 0,07767483 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02378255 0,07757113 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02378255 0,0774677 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02378255 0,07736455 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02378255 0,07726167 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02378255 0,07715906 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02378255 0,07705673 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02378255 0,07695467 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02378255 0,07685288 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02378255 0,07675135 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02378255 0,0766501 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02378255 0,07654911 ! histone ubiquitination GO:0016574 9 7 0,000 0,02378255 0,07644839 ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02378255 0,07634793 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02378255 0,07624774 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02378255 0,0761478 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02378255 0,07604813 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02378255 0,07594872 ! transcription termination GO:0006353 14 7 0,000 0,02378255 0,07584958 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02378255 0,07575068 ! anaphase GO:0051322 18 7 0,000 0,02378255 0,07565205 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02378255 0,07555367 ! axonal fasciculation GO:0007413 19 7 0,000 0,02378255 0,07545555 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02378255 0,07535768 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02378255 0,07526007 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02378255 0,07516271 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02378255 0,0750656 ! diuresis GO:0030146 12 7 0,000 0,02378255 0,07496874 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02378255 0,07487213 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02378255 0,07477577 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02378255 0,07467966 ! antibiotic transport GO:0042891 9 7 0,000 0,02378255 0,07458379 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02378255 0,07448817 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02378255 0,0743928 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02378255 0,07429767 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02378255 0,07420278 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02378255 0,07410813 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02378255 0,07401373 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02378255 0,07391956 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02378255 0,07382563 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02378255 0,07373195 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02378255 0,0736385 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02378255 0,07354528 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02378255 0,07345231 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02378255 0,07335956 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02378255 0,07326705 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02378255 0,07317478 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02378255 0,07308274 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02378255 0,07299092 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02378255 0,07289934 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02378255 0,07280799 ! muscle adaptation GO:0043500 13 7 0,000 0,02378255 0,07271686 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02378255 0,07262597 ! retina homeostasis GO:0001895 12 7 0,000 0,02378255 0,0725353 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02378255 0,07244486 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02378255 0,07235464 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02378255 0,07226465 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02378255 0,07217488 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,02424289 0,07348063 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,02489045 0,07534991 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,02489045 0,07525665 ! respiratory tube development GO:0030323 171 72 1,000 0,02554504 0,07714034 ! regulation of caspase activity GO:0043281 136 74 1,000 0,02687508 0,08105658 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,02687508 0,08095664 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,02687508 0,08085694 ! respiratory system development GO:0060541 175 74 1,000 0,02687508 0,08075748 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02713395 0,08143518 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02713395 0,08133526 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02713395 0,08123558 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02713395 0,08113615 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02713395 0,08103696 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02713395 0,08093801 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02713395 0,08083931 ! male meiosis GO:0007140 9 8 0,000 0,02713395 0,08074084 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02713395 0,08064262 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02713395 0,08054463 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02713395 0,08044688 ! meiotic prophase I GO:0007128 14 8 0,000 0,02713395 0,08034937 ! response to zinc ion GO:0010043 12 8 0,000 0,02713395 0,0802521 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02713395 0,08015506 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02713395 0,08005825 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02713395 0,07996168 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02713395 0,07986534 ! signal peptide processing GO:0006465 12 8 0,000 0,02713395 0,07976923 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02713395 0,07967336 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02713395 0,07957771 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02713395 0,07948229 ! succinate metabolic process GO:0006105 17 8 0,000 0,02713395 0,07938711 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02713395 0,07929214 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02713395 0,07919741 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02713395 0,0791029 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02713395 0,07900862 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02713395 0,07891456 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02713395 0,07882073 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02713395 0,07872712 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02713395 0,07863373 ! reflex GO:0060004 17 8 0,000 0,02713395 0,07854056 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02713395 0,07844761 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02713395 0,07835489 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02713395 0,07826238 ! pigment granule organization GO:0048753 17 8 0,000 0,02713395 0,07817009 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02713395 0,07807801 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02713395 0,07798616 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02713395 0,07789452 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02713395 0,07780309 ! histidine catabolic process GO:0006548 10 8 0,000 0,02713395 0,07771188 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02713395 0,07762088 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02713395 0,0775301 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02713395 0,07743952 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02713395 0,07734916 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02713395 0,07725901 ! melanin metabolic process GO:0006582 17 8 0,000 0,02713395 0,07716907 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02713395 0,07707934 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02713395 0,07698982 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02713395 0,0769005 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02713395 0,07681139 ! macrophage activation GO:0042116 13 8 0,000 0,02713395 0,07672249 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02713395 0,0766338 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02713395 0,0765453 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02713395 0,07645702 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02713395 0,07636893 ! purine salvage GO:0043101 12 8 0,000 0,02713395 0,07628105 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02713395 0,07619337 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02713395 0,07610589 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02713395 0,07601862 ! osteoblast development GO:0002076 17 8 0,000 0,02713395 0,07593154 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02713395 0,07584466 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02713395 0,07575798 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02713395 0,0756715 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02713395 0,07558521 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02713395 0,07549913 ! response to UV-B GO:0010224 17 8 0,000 0,02713395 0,07541323 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02713395 0,07532754 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02713395 0,07524204 ! intermediate filament organization GO:0045109 12 8 0,000 0,02713395 0,07515673 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02713395 0,07507161 ! cellular extravasation GO:0045123 13 8 0,000 0,02713395 0,07498669 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02713395 0,07490196 ! response to antibiotic GO:0046677 11 8 0,000 0,02713395 0,07481742 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02713395 0,07473307 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02713395 0,07464891 ! DNA topological change GO:0006265 12 8 0,000 0,02713395 0,07456494 ! response to tropane GO:0014073 15 8 0,000 0,02713395 0,07448116 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02713395 0,07439757 ! melanosome transport GO:0032402 13 8 0,000 0,02713395 0,07431416 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02713395 0,07423094 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02713395 0,07414791 ! mast cell activation GO:0045576 14 8 0,000 0,02713395 0,07406506 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02713395 0,0739824 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02713395 0,07389993 ! gas homeostasis GO:0033483 14 8 0,000 0,02713395 0,07381763 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02713395 0,07373552 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02713395 0,07365359 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02713395 0,07357185 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02713395 0,07349028 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02713395 0,0734089 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02713395 0,07332769 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02713395 0,07324667 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02713395 0,07316582 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02713395 0,07308515 ! response to tumor cell GO:0002347 16 8 0,000 0,02713395 0,07300466 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02713395 0,07292435 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,02713395 0,07284421 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02713395 0,07276425 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02713395 0,07268447 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02713395 0,07260486 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02713395 0,07252542 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02713395 0,07244616 ! hormone catabolic process GO:0042447 17 8 0,000 0,02713395 0,07236707 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02713395 0,07228815 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02713395 0,0722094 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02713395 0,07213083 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02713395 0,07205243 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02713395 0,07197419 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02713395 0,07189613 ! adult feeding behavior GO:0008343 10 8 0,000 0,02713395 0,07181824 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02713395 0,07174051 ! ATP catabolic process GO:0006200 11 8 0,000 0,02713395 0,07166295 ! blastocyst growth GO:0001832 19 8 0,000 0,02713395 0,07158556 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02713395 0,07150834 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02713395 0,07143129 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02713395 0,07135439 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02713395 0,07127767 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02713395 0,07120111 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02713395 0,07112471 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02713395 0,07104848 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02713395 0,07097241 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02713395 0,07089651 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02713395 0,07082076 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02713395 0,07074518 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02713395 0,07066976 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02713395 0,0705945 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02713395 0,0705194 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02713395 0,07044446 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02713395 0,07036967 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02713395 0,07029505 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02713395 0,07022059 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02713395 0,07014628 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02713395 0,07007213 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,02755043 0,07107255 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,02755043 0,07099758 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,0289215 0,07445229 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,0289215 0,07437392 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,0289215 0,07429572 ! antigen processing and presentation GO:0019882 117 78 1,000 0,02961712 0,07600275 ! steroid biosynthetic process GO:0006694 146 79 1,000 0,03031938 0,07772325 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,03031938 0,07764178 ! axon extension GO:0048675 16 9 0,000 0,03047393 0,07795583 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03047393 0,07787428 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03047393 0,07779291 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03047393 0,0777117 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03047393 0,07763067 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03047393 0,07754981 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03047393 0,07746911 ! reproductive behavior GO:0019098 22 9 0,000 0,03047393 0,07738858 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03047393 0,07730822 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03047393 0,07722802 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03047393 0,07714799 ! UTP metabolic process GO:0046051 10 9 0,000 0,03047393 0,07706813 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03047393 0,07698843 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03047393 0,0769089 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03047393 0,07682953 ! artery development GO:0060840 25 9 0,000 0,03047393 0,07675032 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03047393 0,07667128 ! regulation of glycolysis GO:0006110 20 9 0,000 0,03047393 0,0765924 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03047393 0,07651368 ! equilibrioception GO:0050957 20 9 0,000 0,03047393 0,07643513 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03047393 0,07635673 ! chemosensory behavior GO:0007635 21 9 0,000 0,03047393 0,0762785 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03047393 0,07620042 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03047393 0,07612251 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03047393 0,07604475 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03047393 0,07596716 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03047393 0,07588972 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03047393 0,07581244 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03047393 0,07573531 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03047393 0,07565835 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03047393 0,07558154 ! protein targeting to ER GO:0045047 25 9 0,000 0,03047393 0,07550488 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03047393 0,07542838 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03047393 0,07535204 ! T cell selection GO:0045058 27 9 0,000 0,03047393 0,07527585 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03047393 0,07519981 ! glycine catabolic process GO:0006546 15 9 0,000 0,03047393 0,07512393 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03047393 0,0750482 ! endosome organization GO:0007032 20 9 0,000 0,03047393 0,07497262 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03047393 0,0748972 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03047393 0,07482192 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03047393 0,0747468 ! mannose metabolic process GO:0006013 13 9 0,000 0,03047393 0,07467183 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03047393 0,07459701 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03047393 0,07452234 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03047393 0,07444781 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03047393 0,07437344 ! receptor clustering GO:0043113 20 9 0,000 0,03047393 0,07429921 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03047393 0,07422514 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03047393 0,07415121 ! retinol metabolic process GO:0042572 20 9 0,000 0,03047393 0,07407743 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03047393 0,07400379 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03047393 0,0739303 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03047393 0,07385696 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03047393 0,07378376 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03047393 0,07371071 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03047393 0,0736378 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03047393 0,07356503 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03047393 0,07349241 ! response to amine stimulus GO:0014075 13 9 0,000 0,03047393 0,07341993 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03047393 0,0733476 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03047393 0,07327541 ! erythrocyte development GO:0048821 17 9 0,000 0,03047393 0,07320336 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03047393 0,07313145 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03047393 0,07305968 ! renal water homeostasis GO:0003091 15 9 0,000 0,03047393 0,07298805 ! postreplication repair GO:0006301 25 9 0,000 0,03047393 0,07291657 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03047393 0,07284522 ! icosanoid secretion GO:0032309 15 9 0,000 0,03047393 0,07277401 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03047393 0,07270294 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03047393 0,07263201 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03047393 0,07256122 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03047393 0,07249057 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03047393 0,07242005 ! sterol catabolic process GO:0016127 14 9 0,000 0,03047393 0,07234967 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03047393 0,07227943 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03047393 0,07220932 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03047393 0,07213935 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03047393 0,07206952 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03047393 0,07199982 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03047393 0,07193025 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03047393 0,07186082 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03047393 0,07179153 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03047393 0,07172236 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03047393 0,07165333 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03047393 0,07158444 ! purine base metabolic process GO:0006144 25 9 0,000 0,03047393 0,07151567 ! pigment granule transport GO:0051904 17 9 0,000 0,03047393 0,07144704 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03047393 0,07137854 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03047393 0,07131017 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03047393 0,07124193 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03047393 0,07117382 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03047393 0,07110584 ! mitochondrion localization GO:0051646 18 9 0,000 0,03047393 0,07103799 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,03102825 0,07226121 ! response to hypoxia GO:0001666 178 81 1,000 0,03174365 0,0738569 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,03174365 0,07378663 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,03246555 0,07539291 ! protein import into nucleus GO:0006606 174 82 1,000 0,03246555 0,07532131 ! response to oxygen levels GO:0070482 183 83 1,000 0,03319389 0,07693802 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,03319389 0,07686509 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,03319389 0,0767923 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,03319389 0,07671965 ! nuclear import GO:0051170 177 83 1,000 0,03319389 0,07664714 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03380254 0,07797886 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03380254 0,07790529 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03380254 0,07783187 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03380254 0,07775858 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03380254 0,07768543 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03380254 0,07761241 ! associative learning GO:0008306 21 10 0,000 0,03380254 0,07753954 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03380254 0,0774668 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03380254 0,0773942 ! phosphate transport GO:0006817 24 10 0,000 0,03380254 0,07732173 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03380254 0,0772494 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03380254 0,0771772 ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03380254 0,07710514 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03380254 0,07703322 ! GTP metabolic process GO:0046039 11 10 0,000 0,03380254 0,07696142 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03380254 0,07688977 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03380254 0,07681824 ! social behavior GO:0035176 29 10 0,000 0,03380254 0,07674685 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03380254 0,07667559 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03380254 0,07660446 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03380254 0,07653347 ! androgen metabolic process GO:0008209 17 10 0,000 0,03380254 0,0764626 ! phospholipid efflux GO:0033700 19 10 0,000 0,03380254 0,07639187 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03380254 0,07632127 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03380254 0,07625079 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03380254 0,07618045 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03380254 0,07611024 ! lung alveolus development GO:0048286 26 10 0,000 0,03380254 0,07604016 ! pathogenesis GO:0009405 17 10 0,000 0,03380254 0,0759702 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03380254 0,07590038 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03380254 0,07583068 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03380254 0,07576111 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03380254 0,07569167 ! endoderm development GO:0007492 18 10 0,000 0,03380254 0,07562235 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03380254 0,07555316 ! arginine catabolic process GO:0006527 17 10 0,000 0,03380254 0,0754841 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03380254 0,07541517 ! proline metabolic process GO:0006560 13 10 0,000 0,03380254 0,07534636 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03380254 0,07527767 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03380254 0,07520912 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03380254 0,07514068 ! V(D)J recombination GO:0033151 34 10 0,000 0,03380254 0,07507237 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03380254 0,07500419 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03380254 0,07493612 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03380254 0,07486819 ! B cell proliferation GO:0042100 19 10 0,000 0,03380254 0,07480037 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03380254 0,07473268 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03380254 0,07466511 ! multicellular organism growth GO:0035264 19 10 0,000 0,03380254 0,07459766 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03380254 0,07453033 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03380254 0,07446313 ! ruffle organization GO:0031529 17 10 0,000 0,03380254 0,07439604 ! epithelial cell development GO:0002064 21 10 0,000 0,03380254 0,07432908 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03380254 0,07426224 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03380254 0,07419552 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03380254 0,07412891 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03380254 0,07406243 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03380254 0,07399607 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03380254 0,07392982 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,03380254 0,07386369 ! motor axon guidance GO:0008045 22 10 0,000 0,03380254 0,07379768 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03380254 0,07373179 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03380254 0,07366602 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03380254 0,07360036 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03380254 0,07353483 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03380254 0,0734694 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03380254 0,0734041 ! segment specification GO:0007379 15 10 0,000 0,03380254 0,07333891 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03380254 0,07327383 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03380254 0,07320887 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03380254 0,07314403 ! response to dsRNA GO:0043331 23 10 0,000 0,03380254 0,0730793 ! DNA ligation GO:0006266 18 10 0,000 0,03380254 0,07301469 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03380254 0,07295018 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03380254 0,0728858 ! melanosome localization GO:0032400 16 10 0,000 0,03380254 0,07282152 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03380254 0,07275736 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03380254 0,07269332 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03380254 0,07262938 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03380254 0,07256556 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03380254 0,07250185 ! induction of an organ GO:0001759 17 10 0,000 0,03380254 0,07243825 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03380254 0,07237477 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03380254 0,07231139 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03380254 0,07224813 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03380254 0,07218497 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03380254 0,07212193 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03380254 0,072059 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03380254 0,07199617 ! salivary gland development GO:0007431 28 10 0,000 0,03380254 0,07193346 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03380254 0,07187085 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03380254 0,07180836 ! midbrain development GO:0030901 14 10 0,000 0,03380254 0,07174597 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03380254 0,07168369 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03380254 0,07162152 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03380254 0,07155945 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03380254 0,0714975 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03380254 0,07143565 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03380254 0,07137391 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03380254 0,07131227 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03380254 0,07125074 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03380254 0,07118932 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,03380254 0,071128 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,03380254 0,07106679 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03380254 0,07100568 ! blastocyst formation GO:0001825 18 10 0,000 0,03380254 0,07094468 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03380254 0,07088378 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03380254 0,07082299 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03380254 0,0707623 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03380254 0,07070172 ! response to nicotine GO:0035094 20 10 0,000 0,03380254 0,07064124 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03380254 0,07058086 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03380254 0,07052059 ! response to metal ion GO:0010038 158 84 1,000 0,03392861 0,07072321 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,03466968 0,07220632 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,03466968 0,07214482 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,03466968 0,07208342 ! mitochondrion organization GO:0007005 159 87 1,000 0,0361706 0,07514012 ! nucleosome assembly GO:0006334 126 87 1,000 0,0361706 0,07507628 ! regulation of protein transport GO:0051223 165 87 1,000 0,0361706 0,07501254 GO:0070201|regulation of establishment of protein localization, ! chromatin assembly GO:0031497 128 88 1,000 0,03693036 0,07652322 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,03693036 0,07645837 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03711982 0,07678553 ! respiratory burst GO:0045730 17 11 0,000 0,03711982 0,07672057 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03711982 0,07665572 ! neuron fate specification GO:0048665 18 11 0,000 0,03711982 0,07659097 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03711982 0,07652634 ! thyroid gland development GO:0030878 26 11 0,000 0,03711982 0,07646182 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,03711982 0,0763974 ! synapsis GO:0007129 14 11 0,000 0,03711982 0,07633309 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03711982 0,07626889 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03711982 0,0762048 ! response to pain GO:0048265 27 11 0,000 0,03711982 0,07614082 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03711982 0,07607694 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03711982 0,07601317 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03711982 0,07594951 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,03711982 0,07588595 ! bone resorption GO:0045453 16 11 0,000 0,03711982 0,0758225 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03711982 0,07575916 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03711982 0,07569592 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03711982 0,07563279 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03711982 0,07556976 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03711982 0,07550684 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03711982 0,07544402 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03711982 0,07538131 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03711982 0,0753187 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,03711982 0,07525619 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03711982 0,07519379 ! UV protection GO:0009650 20 11 0,000 0,03711982 0,07513149 ! adult heart development GO:0007512 16 11 0,000 0,03711982 0,0750693 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03711982 0,07500721 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03711982 0,07494522 ! macroautophagy GO:0016236 19 11 0,000 0,03711982 0,07488333 ! temperature homeostasis GO:0001659 18 11 0,000 0,03711982 0,07482155 ! behavioral fear response GO:0001662 27 11 0,000 0,03711982 0,07475986 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03711982 0,07469828 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03711982 0,0746368 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03711982 0,07457542 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03711982 0,07451414 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03711982 0,07445297 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03711982 0,07439189 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03711982 0,07433091 ! regulation of organ growth GO:0046620 14 11 0,000 0,03711982 0,07427004 ! pigment granule localization GO:0051875 20 11 0,000 0,03711982 0,07420926 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03711982 0,07414858 ! vasoconstriction GO:0042310 20 11 0,000 0,03711982 0,074088 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03711982 0,07402752 ! embryonic axis specification GO:0000578 19 11 0,000 0,03711982 0,07396714 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03711982 0,07390686 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03711982 0,07384667 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03711982 0,07378659 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03711982 0,0737266 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03711982 0,07366671 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03711982 0,07360691 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03711982 0,07354721 ! prophase GO:0051324 17 11 0,000 0,03711982 0,07348761 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03711982 0,07342811 ! nucleosome positioning GO:0016584 15 11 0,000 0,03711982 0,0733687 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03711982 0,07330939 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03711982 0,07325017 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03711982 0,07319105 ! acid secretion GO:0046717 20 11 0,000 0,03711982 0,07313203 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03711982 0,0730731 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03711982 0,07301426 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03711982 0,07295552 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03711982 0,07289688 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03711982 0,07283832 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03711982 0,07277987 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03711982 0,0727215 ! cholesterol efflux GO:0033344 21 11 0,000 0,03711982 0,07266323 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03711982 0,07260506 ! oocyte development GO:0048599 20 11 0,000 0,03711982 0,07254697 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03711982 0,07248898 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03711982 0,07243108 ! embryonic gut development GO:0048566 19 11 0,000 0,03711982 0,07237328 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03711982 0,07231556 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03711982 0,07225794 ! activation of innate immune response GO:0002218 16 11 0,000 0,03711982 0,07220041 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03711982 0,07214297 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03711982 0,07208562 ! lysogeny GO:0030069 22 11 0,000 0,03711982 0,07202837 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03711982 0,0719712 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03711982 0,07191413 ! regulation of embryonic development GO:0045995 35 11 0,000 0,03711982 0,07185714 ! regulation of DNA binding GO:0051101 167 89 1,000 0,03769625 0,07291524 ! cellular defense response GO:0006968 123 89 1,000 0,03769625 0,07285755 ! protein localization in nucleus GO:0034504 192 89 1,000 0,03769625 0,07279996 ! regulation of neurological system process GO:0031644 175 89 1,000 0,03769625 0,07274246 ! response to inorganic substance GO:0010035 173 90 1,000 0,03846823 0,07417355 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,03846823 0,07411505 ! response to unfolded protein GO:0006986 139 90 1,000 0,03846823 0,07405665 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,03846823 0,07399833 ! gland development GO:0048732 220 91 1,000 0,03924624 0,07543553 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,04003022 0,07688195 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,04003022 0,07682155 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0404258 0,0775198 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0404258 0,077459 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,0404258 0,07739829 ! virus-host interaction GO:0019048 30 12 0,000 0,0404258 0,07733768 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,0404258 0,07727717 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0404258 0,07721675 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0404258 0,07715642 ! protein complex disassembly GO:0043241 28 12 0,000 0,0404258 0,07709619 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0404258 0,07703606 ! hippocampus development GO:0021766 29 12 0,000 0,0404258 0,07697601 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0404258 0,07691606 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0404258 0,0768562 ! T cell proliferation GO:0042098 32 12 0,000 0,0404258 0,07679644 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0404258 0,07673677 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0404258 0,07667719 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0404258 0,07661771 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0404258 0,07655831 ! drug transport GO:0015893 16 12 0,000 0,0404258 0,07649901 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0404258 0,0764398 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0404258 0,07638068 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0404258 0,07632166 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0404258 0,07626272 ! focal adhesion formation GO:0048041 37 12 0,000 0,0404258 0,07620388 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0404258 0,07614512 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0404258 0,07608646 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0404258 0,07602789 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0404258 0,0759694 ! lipid digestion GO:0044241 21 12 0,000 0,0404258 0,07591101 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0404258 0,07585271 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0404258 0,07579449 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0404258 0,07573637 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0404258 0,07567833 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0404258 0,07562039 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0404258 0,07556253 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0404258 0,07550476 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0404258 0,07544708 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0404258 0,07538948 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0404258 0,07533198 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0404258 0,07527456 ! cranial nerve development GO:0021545 23 12 0,000 0,0404258 0,07521723 ! fucose catabolic process GO:0019317 25 12 0,000 0,0404258 0,07515999 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0404258 0,07510283 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0404258 0,07504576 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0404258 0,07498878 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0404258 0,07493188 ! zymogen activation GO:0031638 18 12 0,000 0,0404258 0,07487507 ! T cell homeostasis GO:0043029 28 12 0,000 0,0404258 0,07481835 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0404258 0,07476171 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0404258 0,07470516 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0404258 0,07464869 ! oocyte differentiation GO:0009994 21 12 0,000 0,0404258 0,07459231 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0404258 0,07453602 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0404258 0,07447981 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,0404258 0,07442368 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0404258 0,07436764 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0404258 0,07431168 ! defense response to fungus GO:0050832 15 12 0,000 0,0404258 0,07425581 ! developmental induction GO:0031128 22 12 0,000 0,0404258 0,07420002 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0404258 0,07414431 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0404258 0,07408869 ! response to cold GO:0009409 17 12 0,000 0,0404258 0,07403315 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0404258 0,0739777 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0404258 0,07392232 ! localization within membrane GO:0051668 26 12 0,000 0,0404258 0,07386703 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,04082014 0,07453185 ! sterol metabolic process GO:0016125 166 94 1,000 0,04161595 0,07592813 ! nucleosome organization GO:0034728 143 95 1,000 0,04241759 0,07733296 ! sex differentiation GO:0007548 171 96 1,000 0,04322501 0,07874623 ! response to protein stimulus GO:0051789 158 96 1,000 0,04322501 0,07868756 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04372052 0,07953033 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04372052 0,07947115 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04372052 0,07941207 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04372052 0,07935307 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04372052 0,07929416 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04372052 0,07923533 ! peroxisomal transport GO:0043574 28 13 0,000 0,04372052 0,0791766 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04372052 0,07911795 ! cartilage condensation GO:0001502 22 13 0,000 0,04372052 0,07905938 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04372052 0,07900091 ! organelle fusion GO:0048284 36 13 0,000 0,04372052 0,07894252 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04372052 0,07888422 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04372052 0,078826 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04372052 0,07876787 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04372052 0,07870982 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04372052 0,07865186 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04372052 0,07859399 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04372052 0,0785362 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04372052 0,07847849 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04372052 0,07842087 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04372052 0,07836334 ! methionine metabolic process GO:0006555 31 13 0,000 0,04372052 0,07830589 ! plasma membrane organization GO:0007009 27 13 0,000 0,04372052 0,07824852 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04372052 0,07819124 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04372052 0,07813404 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04372052 0,07807692 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04372052 0,07801989 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,04372052 0,07796294 ! cytokine metabolic process GO:0042107 24 13 0,000 0,04372052 0,07790607 ! exocrine system development GO:0035272 34 13 0,000 0,04372052 0,07784929 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,04372052 0,07779259 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,04372052 0,07773597 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,04372052 0,07767944 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,04372052 0,07762299 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,04372052 0,07756661 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04372052 0,07751033 ! protein homotetramerization GO:0051289 24 13 0,000 0,04372052 0,07745412 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04372052 0,07739799 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04372052 0,07734195 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04372052 0,07728598 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04372052 0,0772301 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04372052 0,0771743 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,04372052 0,07711858 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04372052 0,07706294 ! histone methylation GO:0016571 29 13 0,000 0,04372052 0,07700737 ! chromatin silencing GO:0006342 29 13 0,000 0,04372052 0,07695189 ! gland morphogenesis GO:0022612 31 13 0,000 0,04372052 0,07689649 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04372052 0,07684117 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04372052 0,07678593 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04372052 0,07673077 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04372052 0,07667568 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04372052 0,07662068 ! spleen development GO:0048536 24 13 0,000 0,04372052 0,07656576 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,04372052 0,07651091 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,04372052 0,07645614 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04372052 0,07640145 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04372052 0,07634684 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04372052 0,07629231 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04372052 0,07623785 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04372052 0,07618347 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04372052 0,07612917 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04372052 0,07607495 ! insulin secretion GO:0030073 24 13 0,000 0,04372052 0,0760208 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04372052 0,07596673 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04372052 0,07591274 ! acrosome reaction GO:0007340 19 13 0,000 0,04372052 0,07585883 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04372052 0,07580499 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04372052 0,07575123 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,04403817 0,07624752 ! transcription initiation GO:0006352 171 97 1,000 0,04403817 0,07619352 ! regulation of protein localization GO:0032880 188 97 1,000 0,04403817 0,0761396 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,0465116 0,08035914 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 1,000 0,0465116 0,08030235 ! rRNA transcription GO:0009303 28 14 0,000 0,04700402 0,08109521 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04700402 0,08103798 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04700402 0,08098083 ! water transport GO:0006833 21 14 0,000 0,04700402 0,08092377 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04700402 0,08086678 ! non-recombinational repair GO:0000726 29 14 0,000 0,04700402 0,08080987 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04700402 0,08075304 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04700402 0,08069629 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04700402 0,08063962 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04700402 0,08058303 ! lipid localization GO:0010876 32 14 0,000 0,04700402 0,08052652 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04700402 0,08047009 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04700402 0,08041374 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04700402 0,08035747 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04700402 0,08030127 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04700402 0,08024516 ! arginine metabolic process GO:0006525 21 14 0,000 0,04700402 0,08018912 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04700402 0,08013316 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,04700402 0,08007728 ! regulation of heart rate GO:0002027 25 14 0,000 0,04700402 0,08002148 ! fear response GO:0042596 34 14 0,000 0,04700402 0,07996575 ! organic alcohol transport GO:0015850 29 14 0,000 0,04700402 0,07991011 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04700402 0,07985454 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,04700402 0,07979904 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04700402 0,07974363 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04700402 0,07968829 ! bone mineralization GO:0030282 18 14 0,000 0,04700402 0,07963303 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04700402 0,07957784 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04700402 0,07952273 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04700402 0,0794677 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04700402 0,07941274 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04700402 0,07935786 ! regulation of cellular pH GO:0030641 27 14 0,000 0,04700402 0,07930305 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04700402 0,07924832 ! ribosome assembly GO:0042255 18 14 0,000 0,04700402 0,07919367 ! cerebellum development GO:0021549 23 14 0,000 0,04700402 0,07913909 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04700402 0,07908459 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04700402 0,07903016 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04700402 0,07897581 ! response to gamma radiation GO:0010332 30 14 0,000 0,04700402 0,07892153 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04700402 0,07886732 ! NADP metabolic process GO:0006739 24 14 0,000 0,04700402 0,07881319 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04700402 0,07875914 ! oxygen transport GO:0015671 22 14 0,000 0,04700402 0,07870516 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04700402 0,07865125 ! male genitalia development GO:0030539 26 14 0,000 0,04700402 0,07859741 ! regulation of RNA stability GO:0043487 33 14 0,000 0,04700402 0,07854365 ! regulation of axon extension GO:0030516 43 14 0,000 0,04700402 0,07848997 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04700402 0,07843635 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,04700402 0,07838281 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05027634 0,08378247 ! lactation GO:0007595 30 15 0,000 0,05027634 0,08372536 ! reproductive cellular process GO:0048610 22 15 0,000 0,05027634 0,08366832 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05027634 0,08361137 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05027634 0,08355449 ! superoxide anion generation GO:0042554 22 15 0,000 0,05027634 0,08349769 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05027634 0,08344096 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,05027634 0,08338432 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05027634 0,08332775 ! copper ion transport GO:0006825 22 15 0,000 0,05027634 0,08327125 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05027634 0,08321484 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05027634 0,0831585 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05027634 0,08310223 ! sulfate transport GO:0008272 27 15 0,000 0,05027634 0,08304604 ! response to cAMP GO:0051591 25 15 0,000 0,05027634 0,08298993 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05027634 0,0829339 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05027634 0,08287793 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,05027634 0,08282205 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05027634 0,08276624 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,05027634 0,0827105 ! vesicle coating GO:0006901 38 15 0,000 0,05027634 0,08265484 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05027634 0,08259926 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,05027634 0,08254375 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,05027634 0,08248831 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05027634 0,08243295 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05027634 0,08237767 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,05027634 0,08232245 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05027634 0,08226731 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05027634 0,08221225 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05027634 0,08215726 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05027634 0,08210234 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05027634 0,08204749 ! histone deacetylation GO:0016575 24 15 0,000 0,05027634 0,08199272 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05027634 0,08193802 ! water homeostasis GO:0030104 28 15 0,000 0,05027634 0,0818834 ! cofactor transport GO:0051181 30 15 0,000 0,05027634 0,08182885 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05027634 0,08177437 ! muscle maintenance GO:0046716 26 15 0,000 0,05027634 0,08171996 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05027634 0,08166562 ! intestinal absorption GO:0050892 31 15 0,000 0,05027634 0,08161136 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05027634 0,08155717 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05027634 0,08150305 ! cell killing GO:0001906 32 15 0,000 0,05027634 0,081449 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,05027634 0,08139503 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,05027634 0,08134113 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05027634 0,08128729 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05027634 0,08123353 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05027634 0,08117984 ! actin filament polymerization GO:0030041 27 15 0,000 0,05027634 0,08112622 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05027634 0,08107267 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,05353752 0,08627451 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,05353752 0,08621763 ! positive regulation of cell size GO:0045793 29 16 0,000 0,05353752 0,08616084 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05353752 0,08610411 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05353752 0,08604747 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05353752 0,08599089 ! bone remodeling GO:0046849 28 16 0,000 0,05353752 0,0859344 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,05353752 0,08587797 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,05353752 0,08582162 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05353752 0,08576534 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05353752 0,08570914 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05353752 0,08565301 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05353752 0,08559696 ! startle response GO:0001964 28 16 0,000 0,05353752 0,08554097 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05353752 0,08548507 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05353752 0,08542923 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,05353752 0,08537347 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05353752 0,08531778 ! glutamate metabolic process GO:0006536 25 16 0,000 0,05353752 0,08526216 ! pituitary gland development GO:0021983 30 16 0,000 0,05353752 0,08520661 ! response to osmotic stress GO:0006970 27 16 0,000 0,05353752 0,08515114 ! lysosomal transport GO:0007041 31 16 0,000 0,05353752 0,08509574 ! fructose metabolic process GO:0006000 25 16 0,000 0,05353752 0,08504041 ! L-amino acid transport GO:0015807 33 16 0,000 0,05353752 0,08498515 ! stem cell development GO:0048864 46 16 0,000 0,05353752 0,08492997 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05353752 0,08487485 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05353752 0,08481981 ! intermediate filament-based process GO:0045103 36 16 0,000 0,05353752 0,08476484 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,05353752 0,08470994 ! negative regulation of immune response GO:0050777 38 16 0,000 0,05353752 0,08465511 ! axon cargo transport GO:0008088 46 16 0,000 0,05353752 0,08460036 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05353752 0,08454567 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05353752 0,08449105 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,05353752 0,08443651 ! neuron recognition GO:0008038 40 16 0,000 0,05353752 0,08438203 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05353752 0,08432763 ! tissue regeneration GO:0042246 27 16 0,000 0,05353752 0,08427329 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05353752 0,08421903 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05353752 0,08416483 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,05353752 0,08411071 ! biomineral formation GO:0031214 22 16 0,000 0,05353752 0,08405665 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05353752 0,08400267 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05353752 0,08394875 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,05353752 0,0838949 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05353752 0,08384112 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05353752 0,08378741 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,05353752 0,08373377 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05353752 0,0836802 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,05353752 0,08362669 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,05353752 0,08357326 ! peptide hormone processing GO:0016486 27 16 0,000 0,05353752 0,08351989 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05678758 0,08853355 ! metencephalon development GO:0022037 32 17 0,000 0,05678758 0,08847708 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,05678758 0,08842069 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,05678758 0,08836437 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,05678758 0,08830813 ! signal complex assembly GO:0007172 47 17 0,000 0,05678758 0,08825195 ! endothelial cell migration GO:0043542 31 17 0,000 0,05678758 0,08819585 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05678758 0,08813981 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05678758 0,08808385 ! glial cell development GO:0021782 28 17 0,000 0,05678758 0,08802796 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05678758 0,08797214 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05678758 0,08791639 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,05678758 0,08786071 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,05678758 0,08780511 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05678758 0,08774957 ! myoblast differentiation GO:0045445 50 17 0,000 0,05678758 0,0876941 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05678758 0,0876387 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,05678758 0,08758338 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,05678758 0,08752812 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,05678758 0,08747293 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,05678758 0,08741781 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,05678758 0,08736276 ! NAD metabolic process GO:0019674 33 17 0,000 0,05678758 0,08730778 ! membrane budding GO:0006900 42 17 0,000 0,05678758 0,08725287 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05678758 0,08719803 ! regulation of protein binding GO:0043393 33 17 0,000 0,05678758 0,08714326 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,05678758 0,08708855 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,05678758 0,08703392 ! genitalia development GO:0048806 32 17 0,000 0,05678758 0,08697935 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,05678758 0,08692485 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05678758 0,08687042 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,05678758 0,08681606 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05678758 0,08676177 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05678758 0,08670754 ! steroid catabolic process GO:0006706 34 17 0,000 0,05678758 0,08665338 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,05678758 0,08659929 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05678758 0,08654527 ! gas transport GO:0015669 26 17 0,000 0,05678758 0,08649131 ! organic cation transport GO:0015695 32 17 0,000 0,05678758 0,08643742 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,05678758 0,0863836 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05678758 0,08632985 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,05678758 0,08627616 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,06002658 0,09114042 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06002658 0,09108381 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06002658 0,09102728 ! limbic system development GO:0021761 40 18 0,000 0,06002658 0,09097081 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06002658 0,09091441 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06002658 0,09085808 ! adult walking behavior GO:0007628 36 18 0,000 0,06002658 0,09080182 ! patterning of blood vessels GO:0001569 43 18 0,000 0,06002658 0,09074563 ! heart looping GO:0001947 34 18 0,000 0,06002658 0,09068951 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06002658 0,09063346 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,06002658 0,09057748 ! centrosome cycle GO:0007098 26 18 0,000 0,06002658 0,09052157 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06002658 0,09046573 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06002658 0,09040995 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,06002658 0,09035425 ! glycine metabolic process GO:0006544 30 18 0,000 0,06002658 0,09029861 ! response to retinoic acid GO:0032526 31 18 0,000 0,06002658 0,09024304 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,06002658 0,09018754 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,06002658 0,09013211 ! DNA integration GO:0015074 32 18 0,000 0,06002658 0,09007674 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,06002658 0,09002145 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06002658 0,08996622 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06002658 0,08991106 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,06002658 0,08985597 ! neural crest cell migration GO:0001755 41 18 0,000 0,06002658 0,08980094 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06002658 0,08974599 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06002658 0,0896911 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06002658 0,08963627 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06002658 0,08958152 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,06002658 0,08952683 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,06002658 0,0894722 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,06002658 0,08941765 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06002658 0,08936316 ! detection of bacterium GO:0016045 22 18 0,000 0,06002658 0,08930873 ! nerve development GO:0021675 34 18 0,000 0,06002658 0,08925438 ! defense response to virus GO:0051607 43 18 0,000 0,06002658 0,08920009 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06002658 0,08914586 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,06325455 0,09388266 ! positive regulation of translation GO:0045727 31 19 0,000 0,06325455 0,09382566 ! negative regulation of defense response GO:0031348 27 19 0,000 0,06325455 0,09376873 ! neuron maturation GO:0042551 46 19 0,000 0,06325455 0,09371186 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,06325455 0,09365507 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,06325455 0,09359834 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,06325455 0,09354169 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,06325455 0,0934851 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,06325455 0,09342858 ! inositol metabolic process GO:0006020 33 19 0,000 0,06325455 0,09337212 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06325455 0,09331574 ! memory GO:0007613 34 19 0,000 0,06325455 0,09325942 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,06325455 0,09320318 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,06325455 0,09314699 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,06325455 0,09309088 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,06325455 0,09303484 ! cerebral cortex development GO:0021987 40 19 0,000 0,06325455 0,09297886 ! pigmentation during development GO:0048066 42 19 0,000 0,06325455 0,09292295 ! response to vitamin A GO:0033189 32 19 0,000 0,06325455 0,09286711 ! heme metabolic process GO:0042168 40 19 0,000 0,06325455 0,09281133 ! neuromuscular junction development GO:0007528 43 19 0,000 0,06325455 0,09275562 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,06325455 0,09269998 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,06325455 0,0926444 ! response to fungus GO:0009620 26 19 0,000 0,06325455 0,09258889 ! peptide cross-linking GO:0018149 39 19 0,000 0,06325455 0,09253345 ! heart process GO:0003015 32 19 0,000 0,06325455 0,09247808 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,06325455 0,09242277 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,06325455 0,09236752 ! visual learning GO:0008542 38 19 0,000 0,06325455 0,09231234 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,06325455 0,09225723 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,06325455 0,09220219 ! vitamin transport GO:0051180 31 19 0,000 0,06325455 0,09214721 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,06325455 0,09209229 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,06325455 0,09203744 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,06325455 0,09198266 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,06325455 0,09192794 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,06325455 0,09187328 ! cilium assembly GO:0042384 38 19 0,000 0,06325455 0,0918187 ! peptide hormone secretion GO:0030072 32 19 0,000 0,06325455 0,09176417 ! protein secretion GO:0009306 45 20 0,000 0,06647152 0,09637384 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,06647152 0,09631668 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,06647152 0,09625959 ! positive regulation of ossification GO:0045778 50 20 0,000 0,06647152 0,09620256 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,06647152 0,09614561 ! skin development GO:0043588 42 20 0,000 0,06647152 0,09608871 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,06647152 0,09603189 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,06647152 0,09597513 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,06647152 0,09591845 ! response to vitamin GO:0033273 36 20 0,000 0,06647152 0,09586182 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,06647152 0,09580527 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,06647152 0,09574878 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,06647152 0,09569236 ! bile acid metabolic process GO:0008206 34 20 0,000 0,06647152 0,095636 ! retinoid metabolic process GO:0001523 34 20 0,000 0,06647152 0,09557971 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,06647152 0,09552349 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,06647152 0,09546733 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,06647152 0,09541124 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 47 20 0,000 0,06647152 0,09535521 ! body fluid secretion GO:0007589 33 20 0,000 0,06647152 0,09529925 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,06647152 0,09524336 ! peptide secretion GO:0002790 38 20 0,000 0,06647152 0,09518753 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,06647152 0,09513177 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,06647152 0,09507607 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,06647152 0,09502044 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,06647152 0,09496487 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,06647152 0,09490937 ! cell-cell junction organization GO:0045216 43 20 0,000 0,06647152 0,09485393 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,06647152 0,09479856 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,06647152 0,09474325 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,06647152 0,094688 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,06647152 0,09463283 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,06647152 0,09457771 ! regulation of glucose import GO:0046324 30 20 0,000 0,06647152 0,09452266 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,06647152 0,09446767 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,06647152 0,09441275 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,06647152 0,09435789 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,06647152 0,09430309 ! regulation of cell killing GO:0031341 46 21 0,000 0,06967754 0,09879409 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,06967754 0,09873679 ! hormone secretion GO:0046879 39 21 0,000 0,06967754 0,09867955 ! cAMP metabolic process GO:0046058 41 21 0,000 0,06967754 0,09862238 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,06967754 0,09856527 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,06967754 0,09850823 ! ovarian follicle development GO:0001541 39 21 0,000 0,06967754 0,09845126 ! smooth muscle contraction GO:0006939 48 21 0,000 0,06967754 0,09839435 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,06967754 0,09833751 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,06967754 0,09828073 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,06967754 0,09822402 ! plasma membrane fusion GO:0045026 33 21 0,000 0,06967754 0,09816737 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,06967754 0,09811079 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,06967754 0,09805428 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,06967754 0,09799783 ! sensory perception of pain GO:0019233 33 21 0,000 0,06967754 0,09794144 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,06967754 0,09788512 ! diencephalon development GO:0021536 36 21 0,000 0,06967754 0,09782886 ! collagen fibril organization GO:0030199 62 21 0,000 0,06967754 0,09777267 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,06967754 0,09771655 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,06967754 0,09766048 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,06967754 0,09760449 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,06967754 0,09754855 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,06967754 0,09749268 ! collagen catabolic process GO:0030574 29 21 0,000 0,06967754 0,09743688 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,06967754 0,09738113 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,06967754 0,09732546 ! sperm-egg recognition GO:0035036 23 21 0,000 0,06967754 0,09726984 ! actin filament-based movement GO:0030048 47 21 0,000 0,06967754 0,09721429 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,06967754 0,0971588 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,07287263 0,1015561 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,07287263 0,1014982 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,07287263 0,10144036 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,07287263 0,1013826 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,07287263 0,10132489 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,07287263 0,10126726 ! microtubule-based transport GO:0010970 59 22 0,000 0,07287263 0,10120969 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,07287263 0,10115218 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,07287263 0,10109474 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,07287263 0,10103737 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,07287263 0,10098006 ! cellular response to starvation GO:0009267 37 22 0,000 0,07287263 0,10092281 ! vacuolar transport GO:0007034 41 22 0,000 0,07287263 0,10086563 ! central nervous system neuron development GO:0021954 47 22 0,000 0,07287263 0,10080852 ! fucose metabolic process GO:0006004 44 22 0,000 0,07287263 0,10075146 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,07287263 0,10069448 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,07287263 0,10063756 ! ureteric bud development GO:0001657 50 22 0,000 0,07287263 0,1005807 ! stem cell differentiation GO:0048863 57 22 0,000 0,07287263 0,10052391 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,07287263 0,10046718 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,07287263 0,10041051 ! cytolysis GO:0019835 27 22 0,000 0,07287263 0,10035391 ! renal system process GO:0003014 42 22 0,000 0,07287263 0,10029737 ! vasodilation GO:0042311 40 22 0,000 0,07287263 0,1002409 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,07287263 0,10018449 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,07287263 0,10012814 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,07287263 0,10007186 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,07287263 0,10001564 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,07287263 0,09995948 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,07287263 0,09990339 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,07287263 0,09984736 ! sarcomere organization GO:0045214 32 22 0,000 0,07287263 0,09979139 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,07287263 0,09973548 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,07287263 0,09967964 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,07287263 0,09962386 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,07287263 0,09956814 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,07287263 0,09951249 ! gut development GO:0048565 44 22 0,000 0,07287263 0,09945689 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,07287263 0,09940136 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,07287263 0,09934589 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,07605684 0,10362904 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,07605684 0,10357127 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,07605684 0,10351357 ! gluconeogenesis GO:0006094 38 23 0,000 0,07605684 0,10345594 ! glycerol metabolic process GO:0006071 40 23 0,000 0,07605684 0,10339837 ! viral genome replication GO:0019079 44 23 0,000 0,07605684 0,10334086 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,07605684 0,10328342 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,07605684 0,10322604 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,07605684 0,10316872 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,07605684 0,10311147 ! regeneration GO:0031099 42 23 0,000 0,07605684 0,10305428 ! axis specification GO:0009798 43 23 0,000 0,07605684 0,10299715 ! visual behavior GO:0007632 46 23 0,000 0,07605684 0,10294009 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,07605684 0,10288309 ! response to ethanol GO:0045471 47 23 0,000 0,07605684 0,10282616 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,07605684 0,10276928 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,07605684 0,10271247 ! peroxisome organization GO:0007031 43 23 0,000 0,07605684 0,10265573 ! lysosome organization GO:0007040 47 23 0,000 0,07605684 0,10259904 ! vesicle targeting GO:0006903 49 23 0,000 0,07605684 0,10254242 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,07605684 0,10248586 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,07605684 0,10242936 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,07605684 0,10237293 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,07605684 0,10231656 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,07605684 0,10226025 ! fatty acid transport GO:0015908 47 23 0,000 0,07605684 0,102204 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,07605684 0,10214781 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,07605684 0,10209168 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,07605684 0,10203562 ! hormone transport GO:0009914 41 23 0,000 0,07605684 0,10197962 ! cell-cell recognition GO:0009988 28 23 0,000 0,07605684 0,10192368 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,07605684 0,1018678 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,07605684 0,10181198 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,07605684 0,10175622 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,07923021 0,10594384 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,07923021 0,10588588 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,07923021 0,10582799 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,07923021 0,10577016 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,07923021 0,10571239 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,07923021 0,10565469 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,07923021 0,10559705 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,07923021 0,10553947 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,07923021 0,10548196 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,07923021 0,10542451 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,07923021 0,10536712 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,07923021 0,10530979 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,07923021 0,10525253 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,07923021 0,10519532 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,07923021 0,10513818 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,07923021 0,1050811 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,07923021 0,10502409 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,07923021 0,10496713 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,07923021 0,10491024 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,07923021 0,10485341 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,07923021 0,10479664 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,07923021 0,10473993 ! membrane depolarization GO:0051899 45 24 0,000 0,07923021 0,10468328 ! pallium development GO:0021543 56 24 0,000 0,07923021 0,1046267 ! oogenesis GO:0048477 44 24 0,000 0,07923021 0,10457017 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,07923021 0,10451371 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,07923021 0,10445731 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,07923021 0,10440097 ! platelet activation GO:0030168 41 24 0,000 0,07923021 0,10434469 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,07923021 0,10428847 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,07923021 0,10423231 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,07923021 0,10417621 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,07923021 0,10412017 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,07923021 0,10406419 ! regulation of amine transport GO:0051952 41 24 0,000 0,07923021 0,10400827 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,08239276 0,10810178 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,08239276 0,10804375 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,08239276 0,10798579 ! leukocyte adhesion GO:0007159 55 25 0,000 0,08239276 0,10792789 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,08239276 0,10787005 ! phototransduction GO:0007602 37 25 0,000 0,08239276 0,10781227 ! keratinization GO:0031424 37 25 0,000 0,08239276 0,10775456 ! vasculogenesis GO:0001570 49 25 0,000 0,08239276 0,1076969 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,08239276 0,10763931 ! vacuole organization GO:0007033 49 25 0,000 0,08239276 0,10758178 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,08239276 0,10752431 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,08239276 0,1074669 ! receptor metabolic process GO:0043112 53 25 0,000 0,08239276 0,10740956 ! chromosome condensation GO:0030261 48 25 0,000 0,08239276 0,10735227 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,08239276 0,10729505 ! regulation of behavior GO:0050795 48 25 0,000 0,08239276 0,10723789 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,08239276 0,10718078 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,08239276 0,10712374 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,08239276 0,10706676 ! immunoglobulin production GO:0002377 62 25 0,000 0,08239276 0,10700984 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,08239276 0,10695298 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,08239276 0,10689618 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,08239276 0,10683944 ! liver development GO:0001889 55 25 0,000 0,08239276 0,10678277 ! protein tetramerization GO:0051262 57 25 0,000 0,08239276 0,10672615 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,08554454 0,11075003 ! myelination GO:0042552 50 26 0,000 0,08554454 0,11069137 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,08554454 0,11063278 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,08554454 0,11057424 ! molting cycle process GO:0022404 52 26 0,000 0,08554454 0,11051577 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,08554454 0,11045735 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,08554454 0,110399 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,08554454 0,11034071 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,08554454 0,11028249 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,08554454 0,11022432 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,08554454 0,11016622 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,08554454 0,11010817 ! digestive system process GO:0022600 49 26 0,000 0,08554454 0,11005019 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,08554454 0,10999227 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,08554454 0,10993441 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,08554454 0,10987661 ! osteoblast differentiation GO:0001649 63 26 0,000 0,08554454 0,10981887 ! neural crest cell development GO:0014032 59 26 0,000 0,08554454 0,10976119 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,08554454 0,10970358 ! negative regulation of cell development GO:0010721 83 26 0,000 0,08554454 0,10964602 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,08554454 0,10958852 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,08554454 0,10953109 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,08554454 0,10947371 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,08554454 0,10941639 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,08554454 0,10935914 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,08554454 0,10930194 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,08554454 0,10924481 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,08554454 0,10918773 ! blastocyst development GO:0001824 50 26 0,000 0,08554454 0,10913071 ! telomere organization GO:0032200 46 26 0,000 0,08554454 0,10907375 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,08554454 0,10901686 ! neural tube closure GO:0001843 58 26 0,000 0,08554454 0,10896002 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,08554454 0,10890324 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,08554454 0,10884652 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,08554454 0,10878986 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,08868558 0,11272574 ! embryonic pattern specification GO:0009880 49 27 0,000 0,08868558 0,11266712 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,08868558 0,11260857 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,08868558 0,11255007 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,08868558 0,11249163 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,08868558 0,11243325 ! iron ion transport GO:0006826 65 27 0,000 0,08868558 0,11237494 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,08868558 0,11231668 ! superoxide metabolic process GO:0006801 41 27 0,000 0,08868558 0,11225849 ! tube lumen formation GO:0035148 59 27 0,000 0,08868558 0,11220035 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,08868558 0,11214228 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,08868558 0,11208426 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,08868558 0,11202631 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,08868558 0,11196841 ! response to starvation GO:0042594 47 27 0,000 0,08868558 0,11191058 ! response to toxin GO:0009636 49 27 0,000 0,08868558 0,1118528 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,08868558 0,11179509 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,08868558 0,11173743 ! leukocyte proliferation GO:0070661 59 27 0,000 0,08868558 0,11167984 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,08868558 0,1116223 ! neuron fate commitment GO:0048663 52 28 0,000 0,09181593 0,11550273 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,09181593 0,11544329 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,09181593 0,1153839 ! vesicle docking GO:0048278 55 28 0,000 0,09181593 0,11532458 ! circadian rhythm GO:0007623 56 28 0,000 0,09181593 0,11526532 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,09181593 0,11520611 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,09181593 0,11514697 ! sperm motility GO:0030317 37 28 0,000 0,09181593 0,11508789 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,09181593 0,11502887 ! base-excision repair GO:0006284 41 28 0,000 0,09181593 0,11496992 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,09181593 0,11491102 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,09181593 0,11485218 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,09181593 0,1147934 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,09181593 0,11473468 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,09181593 0,11467603 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,09181593 0,11461743 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,09181593 0,11455889 ! lipid oxidation GO:0034440 48 28 0,000 0,09181593 0,11450041 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,09181593 0,11444199 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,09181593 0,11438363 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,0949356 0,11820983 ! translational initiation GO:0006413 66 29 0,000 0,0949356 0,11814961 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,0949356 0,11808945 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,0949356 0,11802935 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,0949356 0,11796932 ! primary neural tube formation GO:0014020 61 29 0,000 0,0949356 0,11790934 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,0949356 0,11784943 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,0949356 0,11778958 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,0949356 0,11772979 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,0949356 0,11767005 ! synaptogenesis GO:0007416 46 29 0,000 0,0949356 0,11761038 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,0949356 0,11755077 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,0949356 0,11749122 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,0949356 0,11743174 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,09804465 0,12121614 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,09804465 0,12115482 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,09804465 0,12109357 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,09804465 0,12103238 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,09804465 0,12097125 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,09804465 0,12091019 ! acute-phase response GO:0006953 50 30 0,000 0,09804465 0,12084918 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,09804465 0,12078824 ! myofibril assembly GO:0030239 50 30 0,000 0,09804465 0,12072736 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,09804465 0,12066654 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,09804465 0,12060578 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,09804465 0,12054508 ! cell fate determination GO:0001709 64 30 0,000 0,09804465 0,12048445 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,09804465 0,12042387 ! phospholipid transport GO:0015914 65 30 0,000 0,09804465 0,12036336 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,09804465 0,1203029 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,09804465 0,12024251 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,09804465 0,12018218 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,09804465 0,12012191 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,09804465 0,1200617 ! regulation of coagulation GO:0050818 52 30 0,000 0,09804465 0,12000154 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,10114311 0,1237319 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,10114311 0,12366997 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,10114311 0,12360811 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,10114311 0,1235463 ! cell junction assembly GO:0034329 85 31 0,000 0,10114311 0,12348456 ! regulation of innate immune response GO:0045088 57 31 0,000 0,10114311 0,12342288 ! ovulation cycle process GO:0022602 55 31 0,000 0,10114311 0,12336126 ! male gonad development GO:0008584 56 31 0,000 0,10114311 0,12329971 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,10114311 0,12323821 ! detection of light stimulus GO:0009583 44 31 0,000 0,10114311 0,12317677 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,10114311 0,1231154 ! natural killer cell activation GO:0030101 50 31 0,000 0,10114311 0,12305409 ! ensheathment of neurons GO:0007272 64 31 0,000 0,10114311 0,12299284 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,10114311 0,12293165 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,10114311 0,12287052 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,10114311 0,12280945 ! eye morphogenesis GO:0048592 65 31 0,000 0,10114311 0,12274844 ! response to heat GO:0009408 54 31 0,000 0,10114311 0,12268749 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,10114311 0,12262661 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,10423101 0,12630771 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,10423101 0,12624509 ! collagen metabolic process GO:0032963 49 32 0,000 0,10423101 0,12618253 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,10423101 0,12612003 ! spindle organization GO:0007051 50 32 0,000 0,10423101 0,1260576 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,10423101 0,12599522 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,10423101 0,12593291 ! metanephros development GO:0001656 81 32 0,000 0,10423101 0,12587066 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,10423101 0,12580847 ! muscle cell development GO:0055001 52 32 0,000 0,10423101 0,12574634 ! mesoderm formation GO:0001707 73 32 0,000 0,10423101 0,12568428 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,10423101 0,12562227 ! ovulation cycle GO:0042698 57 32 0,000 0,10423101 0,12556033 ! peripheral nervous system development GO:0007422 68 32 0,000 0,10423101 0,12549845 ! BMP signaling pathway GO:0030509 71 32 0,000 0,10423101 0,12543662 ! hindbrain development GO:0030902 65 32 0,000 0,10423101 0,12537486 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,10423101 0,12531316 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,10423101 0,12525152 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,10423101 0,12518994 ! gene silencing GO:0016458 71 32 0,000 0,10423101 0,12512843 ! regulation of pH GO:0006885 56 33 0,000 0,10730838 0,12875952 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,10730838 0,12869631 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,10730838 0,12863316 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,10730838 0,12857007 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,10730838 0,12850705 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,10730838 0,12844409 ! response to ionizing radiation GO:0010212 74 33 0,000 0,10730838 0,12838118 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,10730838 0,12831834 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,10730838 0,12825557 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,10730838 0,12819285 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,10730838 0,12813019 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,10730838 0,1280676 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,10730838 0,12800507 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,10730838 0,1279426 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,11037527 0,13153502 ! glial cell differentiation GO:0010001 67 34 0,000 0,11037527 0,13147089 ! post-embryonic development GO:0009791 76 34 0,000 0,11037527 0,13140682 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,11037527 0,13134281 ! cholesterol transport GO:0030301 62 34 0,000 0,11037527 0,13127887 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,11037527 0,13121498 ! spliceosome assembly GO:0000245 75 34 0,000 0,11037527 0,13115116 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,11037527 0,13108741 ! formation of primary germ layer GO:0001704 76 34 0,000 0,11037527 0,13102371 ! cell fate specification GO:0001708 56 34 0,000 0,11037527 0,13096007 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,11037527 0,1308965 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,11037527 0,13083299 ! adult locomotory behavior GO:0008344 62 34 0,000 0,11037527 0,13076954 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,11343171 0,13432558 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,11343171 0,1342605 ! negative regulation of secretion GO:0051048 68 35 0,000 0,11343171 0,13419549 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,11343171 0,13413053 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,11343171 0,13406564 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,11343171 0,13400081 ! membrane docking GO:0022406 69 35 0,000 0,11343171 0,13393605 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,11343171 0,13387134 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,11343171 0,1338067 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,11343171 0,13374212 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,11343171 0,13367761 ! ceramide metabolic process GO:0006672 72 35 0,000 0,11343171 0,13361315 ! telencephalon development GO:0021537 81 35 0,000 0,11343171 0,13354876 ! sterol transport GO:0015918 63 35 0,000 0,11343171 0,13348443 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,11343171 0,13342016 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,11343171 0,13335596 ! placenta development GO:0001890 53 35 0,000 0,11343171 0,13329181 ! vesicle localization GO:0051648 70 35 0,000 0,11343171 0,13322773 ! regulation of muscle development GO:0048634 82 36 0,000 0,11647774 0,13673961 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,11647774 0,13667393 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,11647774 0,13660831 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,11647774 0,13654276 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,11647774 0,13647728 ! positive regulation of cell development GO:0010720 85 36 0,000 0,11647774 0,13641185 ! protein targeting to membrane GO:0006612 75 36 0,000 0,11647774 0,13634649 ! regulation of proteolysis GO:0030162 77 36 0,000 0,11647774 0,13628119 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,11647774 0,13621595 ! aerobic respiration GO:0009060 56 36 0,000 0,11647774 0,13615078 ! cytokine production GO:0001816 68 36 0,000 0,11647774 0,13608566 ! embryonic organ development GO:0048568 67 36 0,000 0,11647774 0,13602061 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,11647774 0,13595562 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,11951339 0,13943228 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,11951339 0,13936573 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,11951339 0,13929924 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,11951339 0,13923281 ! sister chromatid segregation GO:0000819 65 37 0,000 0,11951339 0,13916645 ! odontogenesis GO:0042476 74 37 0,000 0,11951339 0,13910014 ! actomyosin structure organization GO:0031032 68 37 0,000 0,11951339 0,13903391 ! cell junction organization GO:0034330 96 37 0,000 0,11951339 0,13896773 ! tissue remodeling GO:0048771 78 37 0,000 0,11951339 0,13890162 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,11951339 0,13883557 ! female gonad development GO:0008585 71 37 0,000 0,11951339 0,13876958 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,11951339 0,13870366 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,11951339 0,1386378 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,11951339 0,138572 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,12253869 0,14201234 ! meiosis I GO:0007127 74 38 0,000 0,12253869 0,141945 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,12253869 0,14187773 ! organic anion transport GO:0015711 82 38 0,000 0,12253869 0,14181052 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,12253869 0,14174338 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,12253869 0,1416763 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,12253869 0,14160928 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,12253869 0,14154232 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,12253869 0,14147543 ! spermatid development GO:0007286 69 38 0,000 0,12253869 0,1414086 ! pigment metabolic process GO:0042440 87 38 0,000 0,12253869 0,14134184 ! neural tube formation GO:0001841 79 38 0,000 0,12253869 0,14127514 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,12555368 0,14468285 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,12555368 0,14461463 ! negative regulation of binding GO:0051100 71 39 0,000 0,12555368 0,14454648 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,12555368 0,1444784 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,12555368 0,14441038 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,12555368 0,14434242 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,12555368 0,14427452 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,12555368 0,14420669 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,12555368 0,14413893 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,12555368 0,14407122 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,12555368 0,14400359 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,1285584 0,14738065 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,1285584 0,14731152 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,1285584 0,14724246 ! learning GO:0007612 82 40 0,000 0,1285584 0,14717346 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,1285584 0,14710452 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,1285584 0,14703566 ! mismatch repair GO:0006298 58 40 0,000 0,1285584 0,14696685 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,1285584 0,14689811 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,1285584 0,14682943 ! RNA export from nucleus GO:0006405 61 41 0,000 0,13155287 0,15017928 ! mRNA catabolic process GO:0006402 79 41 0,000 0,13155287 0,15010914 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,13155287 0,15003906 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,13155287 0,14996905 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,13155287 0,1498991 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,13155287 0,14982921 ! feeding behavior GO:0007631 69 41 0,000 0,13155287 0,1497594 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,13155287 0,14968964 ! mesenchymal cell development GO:0014031 94 41 0,000 0,13155287 0,14961996 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,13155287 0,14955033 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,13155287 0,14948077 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,13155287 0,14941128 ! spermatid differentiation GO:0048515 73 41 0,000 0,13155287 0,14934185 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,13155287 0,14927249 ! RNA modification GO:0009451 64 41 0,000 0,13155287 0,14920319 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,13453714 0,15251705 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,13453714 0,15244631 ! T cell differentiation GO:0030217 93 42 0,000 0,13453714 0,15237563 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,13453714 0,15230502 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,13453714 0,15223448 ! regulation of protein secretion GO:0050708 77 42 0,000 0,13453714 0,152164 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,13453714 0,15209358 ! cytokinesis GO:0000910 84 42 0,000 0,13453714 0,15202324 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,13453714 0,15195295 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,13751124 0,15524028 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,13751124 0,15516857 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,13751124 0,15509693 ! regulation of tube size GO:0035150 76 43 0,000 0,13751124 0,15502536 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,13751124 0,15495386 ! glucose transport GO:0015758 66 43 0,000 0,13751124 0,15488242 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,13751124 0,15481104 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,13751124 0,15473973 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,13751124 0,15466849 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,13751124 0,15459731 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,13751124 0,1545262 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,13751124 0,15445515 ! ion transmembrane transport GO:0034220 79 43 0,000 0,13751124 0,15438417 ! neuron migration GO:0001764 85 43 0,000 0,13751124 0,15431326 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,1404752 0,157567 ! hexose transport GO:0008645 68 44 0,000 0,1404752 0,15749469 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,1404752 0,15742244 ! striated muscle contraction GO:0006941 85 44 0,000 0,1404752 0,15735026 ! phagocytosis GO:0006909 105 44 0,000 0,1404752 0,15727815 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,1404752 0,1572061 ! double-strand break repair GO:0006302 85 44 0,000 0,1404752 0,15713412 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,14342906 0,16036485 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,14342906 0,16029149 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,14342906 0,1602182 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,14342906 0,16014497 ! B cell differentiation GO:0030183 124 45 0,000 0,14342906 0,16007181 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,14342906 0,15999872 ! female gamete generation GO:0007292 71 45 0,000 0,14342906 0,1599257 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,14342906 0,15985274 ! polyol metabolic process GO:0019751 77 45 0,000 0,14342906 0,15977985 ! developmental growth GO:0048589 88 45 0,000 0,14342906 0,15970702 ! maintenance of location in cell GO:0051651 101 45 0,000 0,14342906 0,15963426 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,14637285 0,16283647 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,14637285 0,16276235 ! glycolysis GO:0006096 71 46 0,000 0,14637285 0,1626883 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,14637285 0,16261432 ! leukocyte migration GO:0050900 75 46 0,000 0,14637285 0,1625404 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,14637285 0,16246655 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,14637285 0,16239277 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,14637285 0,16231906 ! neural tube development GO:0021915 91 47 0,000 0,14930661 0,1654973 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,14930661 0,16542225 ! positive regulation of defense response GO:0031349 88 48 0,000 0,15223037 0,16858513 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,15223037 0,16850874 ! mitochondrial transport GO:0006839 94 48 0,000 0,15223037 0,16843242 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,15223037 0,16835617 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,15223037 0,16828 ! endosome transport GO:0016197 127 48 0,000 0,15223037 0,16820388 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,15223037 0,16812784 ! male sex differentiation GO:0046661 93 48 0,000 0,15223037 0,16805187 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,15223037 0,16797597 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,15223037 0,16790013 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,15223037 0,16782436 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,15223037 0,16774866 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,15514416 0,17088241 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,15514416 0,1708054 ! JNK cascade GO:0007254 106 49 0,000 0,15514416 0,17072846 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,15514416 0,17065159 ! protein homooligomerization GO:0051260 84 49 0,000 0,15514416 0,17057479 ! regulation of action potential GO:0001508 102 50 0,000 0,15804802 0,17368929 ! regulation of ion transport GO:0043269 86 50 0,000 0,15804802 0,1736112 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,15804802 0,17353317 ! endocrine system development GO:0035270 109 50 0,000 0,15804802 0,17345521 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,15804802 0,17337732 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,15804802 0,17329951 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,15804802 0,17322176 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,15804802 0,17314408 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,16094197 0,17623543 ! response to temperature stimulus GO:0009266 84 51 0,000 0,16094197 0,17615647 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,16094197 0,17607758 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,16382607 0,17915268 ! Notch signaling pathway GO:0007219 111 52 0,000 0,16382607 0,17907252 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,16382607 0,17899243 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,16382607 0,17891242 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,16382607 0,17883247 ! excretion GO:0007588 87 52 0,000 0,16382607 0,1787526 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,16382607 0,1786728 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,16382607 0,17859307 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,16382607 0,17851342 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,16670033 0,18156438 ! positive regulation of growth GO:0045927 96 53 0,000 0,16670033 0,18148346 ! inner ear development GO:0048839 89 53 0,000 0,16670033 0,18140263 ! chromatin remodeling GO:0006338 122 53 0,000 0,16670033 0,18132186 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,16670033 0,18124116 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,16670033 0,18116054 ! vesicle organization GO:0016050 127 53 0,000 0,16670033 0,18107999 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,16670033 0,18099951 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,16670033 0,1809191 ! cartilage development GO:0051216 99 53 0,000 0,16670033 0,18083876 ! synapse organization GO:0050808 102 53 0,000 0,16670033 0,1807585 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,16956479 0,18378295 ! regulation of translational initiation GO:0006446 87 54 0,000 0,16956479 0,18370145 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,16956479 0,18362002 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,16956479 0,18353867 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,16956479 0,18345738 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,16956479 0,18337617 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,16956479 0,18329503 ! membrane fusion GO:0006944 122 54 0,000 0,16956479 0,18321396 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,16956479 0,18313297 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,16956479 0,18305204 ! RNA catabolic process GO:0006401 103 55 0,000 0,17241948 0,18605159 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,17241948 0,18596944 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,17241948 0,18588737 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,17241948 0,18580538 ! cell recognition GO:0008037 98 55 0,000 0,17241948 0,18572345 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,17241948 0,1856416 ! cell maturation GO:0048469 107 55 0,000 0,17241948 0,18555982 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,17241948 0,18547811 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,17241948 0,18539647 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,17526444 0,18837265 ! glucose catabolic process GO:0006007 88 56 0,000 0,17526444 0,18828981 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,17526444 0,18820705 ! RNA elongation GO:0006354 90 56 0,000 0,17526444 0,18812435 ! chloride transport GO:0006821 102 57 0,000 0,1780997 0,19108369 ! muscle fiber development GO:0048747 131 57 0,000 0,1780997 0,19099981 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,1780997 0,190916 ! heart morphogenesis GO:0003007 105 57 0,000 0,1780997 0,19083227 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,1780997 0,19074861 ! regulation of actin filament length GO:0030832 118 58 0,000 0,1809253 0,19368996 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,1809253 0,19360512 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,1809253 0,19352036 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,1809253 0,19343567 ! gastrulation GO:0007369 122 58 0,000 0,1809253 0,19335105 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,1809253 0,1932665 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,1809253 0,19318203 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,1809253 0,19309764 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,18654761 0,19901127 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,18654761 0,19892441 ! adult behavior GO:0030534 104 60 0,000 0,18654761 0,19883761 ! kidney development GO:0001822 133 60 0,000 0,18654761 0,1987509 ! positive regulation of secretion GO:0051047 110 61 0,000 0,1893444 0,2016427 ! regulation of cellular component size GO:0032535 125 61 0,000 0,1893444 0,20155484 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,1893444 0,20146706 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,1893444 0,20137935 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,1893444 0,20129172 ! regulation of heart contraction GO:0008016 123 61 0,000 0,1893444 0,20120416 ! camera-type eye development GO:0043010 126 61 0,000 0,1893444 0,20111668 ! proton transport GO:0015992 117 61 0,000 0,1893444 0,20102928 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,1893444 0,20094195 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,19213165 0,20381138 ! tRNA processing GO:0008033 102 62 0,000 0,19213165 0,20372292 ! regulation of mitosis GO:0007088 112 63 0,000 0,19490939 0,20657859 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,19490939 0,206489 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,19490939 0,2063995 ! hydrogen transport GO:0006818 121 64 0,000 0,19767766 0,20924027 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,19767766 0,20914965 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,19767766 0,20905911 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,2004365 0,21188505 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,2004365 0,21179341 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,2004365 0,21170184 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,2004365 0,21161035 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,2004365 0,21151894 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,2004365 0,21142762 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,20318592 0,2142353 ! gonad development GO:0008406 115 66 0,000 0,20318592 0,21414288 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,20592596 0,2169371 ! activation of MAPK activity GO:0000187 124 67 0,000 0,20592596 0,21684359 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,20592596 0,21675016 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,20592596 0,21665682 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,20592596 0,21656355 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,20592596 0,21647036 ! secondary metabolic process GO:0019748 125 67 0,000 0,20592596 0,21637726 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,20865666 0,21915229 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,20865666 0,21905811 ! hexose catabolic process GO:0019320 113 68 0,000 0,20865666 0,21896401 ! extracellular matrix organization GO:0030198 146 68 0,000 0,20865666 0,21887 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,20865666 0,21877606 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,20865666 0,21868221 ! regulation of lipase activity GO:0060191 137 68 0,000 0,20865666 0,21858843 ! adaptive immune response GO:0002250 126 68 0,000 0,20865666 0,21849474 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,20865666 0,21840112 ! negative regulation of cell size GO:0045792 144 69 0,000 0,21137805 0,22115485 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,21137805 0,22106018 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,21137805 0,22096558 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,21137805 0,22087107 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,21137805 0,22077664 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,21137805 0,2206823 ! developmental maturation GO:0021700 128 69 0,000 0,21137805 0,22058803 ! single fertilization GO:0007338 83 69 0,000 0,21137805 0,22049384 ! cell redox homeostasis GO:0045454 114 70 0,000 0,21409015 0,22322759 ! germ cell development GO:0007281 133 70 0,000 0,21409015 0,22313235 ! activation of immune response GO:0002253 120 70 0,000 0,21409015 0,2230372 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,21409015 0,22294213 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,216793 0,22566055 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,216793 0,22556444 ! appendage morphogenesis GO:0035107 150 72 0,000 0,21948664 0,22826984 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,21948664 0,2281727 ! actin filament organization GO:0007015 167 72 0,000 0,21948664 0,22807565 ! B cell activation GO:0042113 179 72 0,000 0,21948664 0,22797868 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,21948664 0,22788179 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,21948664 0,22778499 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,21948664 0,22768826 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,21948664 0,22759162 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,21948664 0,22749506 ! appendage development GO:0048736 151 73 0,000 0,22217108 0,23017979 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,22217108 0,23008222 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,22217108 0,22998473 ! regulation of immune effector process GO:0002697 156 73 0,000 0,22217108 0,22988732 ! acute inflammatory response GO:0002526 118 74 0,000 0,22484637 0,23255702 ! amino acid transport GO:0006865 148 74 0,000 0,22484637 0,2324586 ! transition metal ion transport GO:0000041 143 75 0,000 0,22751253 0,23511553 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,22751253 0,23501612 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,22751253 0,23491679 ! eye development GO:0001654 155 75 0,000 0,22751253 0,23481754 ! axon guidance GO:0007411 162 75 0,000 0,22751253 0,23471838 ! rhythmic process GO:0048511 142 75 0,000 0,22751253 0,2346193 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,2301696 0,23725921 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,2301696 0,23715914 ! learning or memory GO:0007611 161 76 0,000 0,2301696 0,23705916 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,2301696 0,23695926 ! regulation of blood pressure GO:0008217 134 76 0,000 0,2301696 0,23685945 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,2301696 0,23675972 ! amine catabolic process GO:0009310 136 77 0,000 0,2328176 0,23938274 ! neurotransmitter transport GO:0006836 142 77 0,000 0,2328176 0,23928203 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,2328176 0,23918141 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,2328176 0,23908087 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,2328176 0,23898042 ! regulation of catabolic process GO:0009894 173 77 0,000 0,2328176 0,23888005 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,23545657 0,24148631 ! fertilization GO:0009566 99 78 0,000 0,23545657 0,24138497 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,23545657 0,24128372 ! blood coagulation GO:0007596 151 79 0,000 0,23808653 0,24387647 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,23808653 0,24377426 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,23808653 0,24367214 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,23808653 0,2435701 ! protein oligomerization GO:0051259 149 79 0,000 0,23808653 0,24346814 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,24070752 0,24604539 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,24070752 0,24594248 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,24070752 0,24583966 ! meiosis GO:0007126 143 81 0,000 0,24331957 0,24840356 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,24331957 0,24829979 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,24331957 0,24819612 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,24592271 0,25074673 ! meiotic cell cycle GO:0051321 144 82 0,000 0,24592271 0,25064212 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,24851696 0,25318054 ! exocytosis GO:0006887 153 83 0,000 0,24851696 0,253075 ! inorganic anion transport GO:0015698 156 83 0,000 0,24851696 0,25296955 ! T cell activation GO:0042110 189 84 0,000 0,25110236 0,25549482 ! response to nutrient GO:0007584 135 84 0,000 0,25110236 0,25538845 ! digestion GO:0007586 130 84 0,000 0,25110236 0,25528218 ! regulation of ligase activity GO:0051340 147 84 0,000 0,25110236 0,25517598 ! hemostasis GO:0007599 165 85 0,000 0,25367894 0,25768717 ! negative regulation of transport GO:0051051 164 85 0,000 0,25367894 0,25758007 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,25367894 0,25747306 ! negative regulation of growth GO:0045926 168 85 0,000 0,25367894 0,25736613 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,25367894 0,2572593 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,25624673 0,2597555 ! regulation of lyase activity GO:0051339 169 86 0,000 0,25624673 0,25964776 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,25624673 0,25954011 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,25880575 0,2620234 ! alcohol catabolic process GO:0046164 142 87 0,000 0,25880575 0,26191485 ! cellular respiration GO:0045333 143 88 0,000 0,26135604 0,26438626 ! amine biosynthetic process GO:0009309 146 88 0,000 0,26135604 0,26427683 ! sensory perception of smell GO:0007608 117 88 0,000 0,26135604 0,26416749 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,26389763 0,2666261 ! tube morphogenesis GO:0035239 194 89 0,000 0,26389763 0,26651588 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,26643055 0,26896274 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,26895482 0,27139885 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,26895482 0,2712868 ! defense response to bacterium GO:0042742 112 91 0,000 0,26895482 0,27117483 ! bone development GO:0060348 206 92 0,000 0,27147047 0,27359833 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,27397754 0,27601119 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,27397754 0,27589742 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,27397754 0,27578374 ! vitamin metabolic process GO:0006766 153 93 0,000 0,27397754 0,27567015 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,27647605 0,27806957 ! female pregnancy GO:0007565 166 94 0,000 0,27647605 0,27795514 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,27647605 0,27784081 ! regulation of membrane potential GO:0042391 179 94 0,000 0,27647605 0,27772656 ! regulation of defense response GO:0031347 171 95 0,000 0,27896604 0,28011263 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,27896604 0,27999755 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,27896604 0,27988256 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,27896604 0,27976766 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,27896604 0,27965286 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,27896604 0,27953816 ! regulation of T cell activation GO:0050863 175 96 0,000 0,28144752 0,2819091 ! forebrain development GO:0030900 210 98 0,000 0,28638511 0,28673722 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,28638511 0,28661975 ! positive regulation of immune response GO:0050778 175 100 0,000 0,29128904 0,29140832 ! hormone metabolic process GO:0042445 171 100 0,000 0,29128904 0,29128904