pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1169-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 10 5 2,000 1,025E-06 2,357E-03 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 1,025E-06 1,179E-03 GO:0031272|regulation of pseudopodium assembly, ! macrophage differentiation GO:0030225 10 6 2,000 2,043E-06 1,566E-03 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 3,563E-06 2,049E-03 ! establishment of nucleus localization GO:0040023 13 7 2,000 3,563E-06 1,639E-03 ! nucleus localization GO:0051647 15 9 2,000 8,492E-06 3,255E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 1,209E-05 3,972E-03 ! protein sumoylation GO:0016925 12 10 2,000 1,209E-05 3,476E-03 ! filopodium assembly GO:0046847 19 11 2,000 1,657E-05 4,234E-03 ! microspike assembly GO:0030035 23 12 2,000 2,201E-05 5,063E-03 ! regulation of erythrocyte differentiation GO:0045646 27 14 2,000 3,617E-05 7,563E-03 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 1,29E-04 0,0247308 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 1,29E-04 0,02282843 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 1,706E-04 0,0280338 ! regulation of homeostatic process GO:0032844 105 60 3,000 1,881E-04 0,02884957 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 1,944E-04 0,02793792 ! protein maturation by protein folding GO:0022417 12 5 1,000 2,207E-04 0,02985271 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 2,207E-04 0,02819422 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 1,000 2,207E-04 0,02671032 ! apical protein localization GO:0045176 6 5 1,000 2,207E-04 0,0253748 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 2,207E-04 0,02416648 ! triglyceride catabolic process GO:0019433 6 5 1,000 2,207E-04 0,023068 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 3,103E-04 0,03102925 ! response to drug GO:0042493 108 69 3,000 3,229E-04 0,0309473 ! prostate gland development GO:0030850 9 6 1,000 3,3E-04 0,03035579 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 3,3E-04 0,02918826 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 3,3E-04 0,02810721 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 1,000 3,3E-04 0,02710338 GO:0031958|corticosteroid receptor signaling pathway, ! ER overload response GO:0006983 7 6 1,000 3,3E-04 0,02616879 ! glycerol ether catabolic process GO:0044269 8 6 1,000 3,3E-04 0,02529649 GO:0046464|acylglycerol catabolic process, ! regulation of meiosis GO:0040020 10 6 1,000 3,3E-04 0,02448048 GO:0051445|regulation of meiotic cell cycle, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 4,605E-04 0,03309922 ! neutral lipid catabolic process GO:0046461 9 7 1,000 4,605E-04 0,03209621 ! oligopeptide transport GO:0006857 11 7 1,000 4,605E-04 0,03115221 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 4,605E-04 0,03026214 ! microtubule bundle formation GO:0001578 8 7 1,000 4,605E-04 0,02942153 ! glycerolipid catabolic process GO:0046503 9 7 1,000 4,605E-04 0,02862635 ! asymmetric protein localization GO:0008105 8 7 1,000 4,605E-04 0,02787303 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 5,553E-04 0,03274675 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 6,121E-04 0,03519695 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 6,121E-04 0,03433849 ! middle ear morphogenesis GO:0042474 9 8 1,000 6,121E-04 0,03352091 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 6,121E-04 0,03274135 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 6,121E-04 0,03199723 ! regulation of telomere maintenance GO:0032204 10 8 1,000 6,121E-04 0,03128618 ! pigmentation GO:0043473 74 38 2,000 7,722E-04 0,0386085 ! CTP metabolic process GO:0046036 9 9 1,000 7,846E-04 0,03839465 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of phagocytosis GO:0050766 11 9 1,000 7,846E-04 0,03759477 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 7,846E-04 0,03682753 ! sequestering of metal ion GO:0051238 11 9 1,000 7,846E-04 0,03609097 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 8,982E-04 0,04050645 ! cortical actin cytoskeleton organization GO:0030866 19 10 1,000 9,777E-04 0,04324489 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 9,777E-04 0,04242895 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 1,000 9,777E-04 0,04164323 ! DNA methylation GO:0006306 15 10 1,000 9,777E-04 0,04088608 GO:0006305|DNA alkylation, ! peptidyl-amino acid modification GO:0018193 147 93 3,000 1,001E-03 0,0410944 ! regulation of cell projection organization GO:0031344 83 44 2,000 1,188E-03 0,04792384 ! cortical cytoskeleton organization GO:0030865 20 11 1,000 1,191E-03 0,04724114 ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,191E-03 0,04644044 ! regulation of phagocytosis GO:0050764 14 11 1,000 1,191E-03 0,04566643 ! positive regulation of cell cycle GO:0045787 77 45 2,000 1,268E-03 0,04781653 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 1,000 1,425E-03 0,05286867 ! histone acetylation GO:0016573 23 12 1,000 1,425E-03 0,05202948 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,425E-03 0,05121652 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,679E-03 0,05941393 ! cellular pigmentation GO:0033059 24 13 1,000 1,679E-03 0,05851372 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 1,823E-03 0,06259662 ! aging GO:0007568 79 52 2,000 1,929E-03 0,06522953 ! establishment of organelle localization GO:0051656 85 52 2,000 1,929E-03 0,06428418 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 1,953E-03 0,06416701 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,953E-03 0,06326325 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 1,000 1,953E-03 0,06238459 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 1,953E-03 0,06153001 GO:0031114|regulation of microtubule depolymerization, ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 1,953E-03 0,06069852 ! cell projection assembly GO:0030031 76 53 2,000 2,037E-03 0,06247673 ! regulation of protein complex assembly GO:0043254 81 54 2,000 2,15E-03 0,06505945 ! lipid phosphorylation GO:0046834 23 15 1,000 2,246E-03 0,06710099 ! regulation of neurotransmitter secretion GO:0046928 26 15 1,000 2,246E-03 0,06624072 ! regulation of survival gene product expression GO:0045884 20 15 1,000 2,246E-03 0,06540223 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 1,000 2,246E-03 0,0645847 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 2,246E-03 0,06378736 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 2,246E-03 0,06300946 ! dopamine metabolic process GO:0042417 30 15 1,000 2,246E-03 0,06225031 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 2,246E-03 0,06150924 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 2,386E-03 0,06456825 ! protein amino acid acetylation GO:0006473 28 16 1,000 2,559E-03 0,06845032 ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,559E-03 0,06766353 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 1,000 2,559E-03 0,06689463 ! protein export from nucleus GO:0006611 24 16 1,000 2,559E-03 0,066143 ! DNA replication initiation GO:0006270 25 16 1,000 2,559E-03 0,06540808 ! G1 phase GO:0051318 27 16 1,000 2,559E-03 0,06468931 ! negative regulation of translation GO:0017148 22 16 1,000 2,559E-03 0,06398617 ! myeloid cell differentiation GO:0030099 85 59 2,000 2,77E-03 0,06850643 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 2,892E-03 0,07075653 ! peptidyl-serine modification GO:0018209 27 17 1,000 2,892E-03 0,07001173 ! organelle localization GO:0051640 96 62 2,000 3,19E-03 0,07642396 ! positive regulation of DNA replication GO:0045740 29 18 1,000 3,243E-03 0,07690215 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 3,243E-03 0,07611743 ! glutamine metabolic process GO:0006541 23 18 1,000 3,243E-03 0,07534857 ! somitogenesis GO:0001756 24 18 1,000 3,243E-03 0,07459508 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 3,243E-03 0,07385652 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 3,614E-03 0,08148515 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 3,614E-03 0,08069403 ! response to alkaloid GO:0043279 32 19 1,000 3,614E-03 0,07991813 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 3,614E-03 0,079157 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 3,614E-03 0,07841024 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 3,614E-03 0,07767743 ! apoptotic nuclear changes GO:0030262 24 19 1,000 3,614E-03 0,0769582 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 3,614E-03 0,07625216 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 3,614E-03 0,07555896 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 1,000 3,614E-03 0,07487824 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 3,614E-03 0,07420969 ! protein stabilization GO:0050821 26 19 1,000 3,614E-03 0,07355297 ! regulation of neurotransmitter transport GO:0051588 35 20 1,000 4,003E-03 0,08075985 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 4,003E-03 0,08005759 ! DNA modification GO:0006304 28 20 1,000 4,003E-03 0,07936744 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 4,411E-03 0,08670514 ! protein amino acid acylation GO:0043543 37 21 1,000 4,411E-03 0,08597035 ! dendrite development GO:0016358 35 21 1,000 4,411E-03 0,08524791 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 4,411E-03 0,08453752 ! cell aging GO:0007569 32 21 1,000 4,411E-03 0,08383886 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 1,000 4,411E-03 0,08315165 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 4,837E-03 0,09044477 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 4,837E-03 0,08971538 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 37 23 1,000 5,281E-03 0,09717459 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 5,281E-03 0,09640337 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 5,281E-03 0,09564429 ! cellular response to oxidative stress GO:0034599 33 23 1,000 5,281E-03 0,09489706 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 5,744E-03 0,10240654 ! fat cell differentiation GO:0045444 37 24 1,000 5,744E-03 0,1016188 ! glutathione metabolic process GO:0006749 29 24 1,000 5,744E-03 0,10084308 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 5,744E-03 0,10007912 ! peptide transport GO:0015833 43 25 1,000 6,224E-03 0,10763277 ! iron ion homeostasis GO:0055072 39 25 1,000 6,224E-03 0,10682954 ! regulation of chromosome organization GO:0033044 35 25 1,000 6,224E-03 0,10603821 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 6,224E-03 0,10525852 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 6,722E-03 0,11285083 ! catechol metabolic process GO:0009712 43 27 1,000 7,238E-03 0,12062505 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 1,000 7,238E-03 0,11975725 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 7,705E-03 0,12658748 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 7,705E-03 0,12568969 ! phenol metabolic process GO:0018958 44 28 1,000 7,77E-03 0,12585803 ! positive regulation of endocytosis GO:0045807 33 28 1,000 7,77E-03 0,12497791 ! triglyceride metabolic process GO:0006641 34 28 1,000 7,77E-03 0,12411001 ! sterol biosynthetic process GO:0016126 40 28 1,000 7,77E-03 0,12325407 ! cell cycle arrest GO:0007050 150 86 2,000 7,957E-03 0,12534777 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 7,957E-03 0,12449506 ! interphase GO:0051325 159 88 2,000 8,474E-03 0,13169613 ! regulation of microtubule-based process GO:0032886 58 30 1,000 8,887E-03 0,13718856 ! leukocyte differentiation GO:0002521 143 90 2,000 9,011E-03 0,13817231 ! protein modification by small protein conjugation GO:0032446 140 90 2,000 9,011E-03 0,13725727 ! segmentation GO:0035282 41 31 1,000 9,471E-03 0,14331568 ! response to mechanical stimulus GO:0009612 43 31 1,000 9,471E-03 0,14237897 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 0,01007182 0,15042333 ! neutral lipid metabolic process GO:0006638 41 32 1,000 0,01007182 0,14945285 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 48 32 1,000 0,01007182 0,14849482 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,01068884 0,15658814 ! ear morphogenesis GO:0042471 42 33 1,000 0,01068884 0,15559708 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 1,000 0,01068884 0,15461848 ! nucleus organization GO:0006997 49 33 1,000 0,01068884 0,15365212 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 1,000 0,01068884 0,15269775 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,01073959 0,15247561 ! protein modification by small protein conjugation or removal GO:0070647 148 96 2,000 0,01073959 0,15154017 ! protein maturation GO:0051604 129 96 2,000 0,01073959 0,15061615 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 2,000 0,01104498 0,15396039 ! glycerol ether metabolic process GO:0006662 44 34 1,000 0,01132219 0,15687373 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,01132219 0,15593437 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,01167078 0,1597785 ! glycogen metabolic process GO:0005977 48 35 1,000 0,0119717 0,16292849 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,0119717 0,16197009 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01263721 0,16997421 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 1,000 0,01263721 0,16898598 ! organic ether metabolic process GO:0018904 46 36 1,000 0,01263721 0,16800919 ! glucan metabolic process GO:0044042 49 36 1,000 0,01263721 0,16704362 GO:0006073|cellular glucan metabolic process, ! ribonucleoside metabolic process GO:0009119 48 37 1,000 0,01331856 0,17504393 ! amino acid activation GO:0043038 52 37 1,000 0,01331856 0,17404936 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! gliogenesis GO:0042063 71 38 1,000 0,01401558 0,18212337 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 0,01472812 0,19030713 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,01472812 0,18924396 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,01472812 0,18819261 ! cell growth GO:0016049 61 39 1,000 0,01472812 0,18715287 ! response to calcium ion GO:0051592 58 40 1,000 0,01545601 0,19532318 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,01545601 0,19425584 ! peptide metabolic process GO:0006518 56 40 1,000 0,01545601 0,1932001 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 0,01545601 0,19215578 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,01545601 0,19112268 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,0161991 0,19924022 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,0161991 0,19818043 ! biopolymer methylation GO:0043414 62 41 1,000 0,0161991 0,19713186 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,01695722 0,20527166 ! cellular component disassembly GO:0022411 64 42 1,000 0,01695722 0,20419694 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,01695722 0,20313341 ! regulation of cell shape GO:0008360 78 42 1,000 0,01695722 0,20208091 ! positive regulation of binding GO:0051099 59 43 1,000 0,01773024 0,21020383 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 0,01773024 0,20912586 ! activation of caspase activity GO:0006919 65 43 1,000 0,01773024 0,20805889 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 0,01773024 0,20700275 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01773024 0,20595729 ! methylation GO:0032259 64 43 1,000 0,01773024 0,20492233 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,01851798 0,21295673 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,01932029 0,22107798 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,02013703 0,22928304 ! regulation of ossification GO:0030278 71 46 1,000 0,02013703 0,22815357 ! histone modification GO:0016570 68 46 1,000 0,02013703 0,22703517 ! response to UV GO:0009411 75 46 1,000 0,02013703 0,22592768 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02096804 0,23410921 ! glutamine family amino acid metabolic process GO:0009064 59 47 1,000 0,02096804 0,23297825 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,02181317 0,24120336 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,02181317 0,24004928 ! regulation of DNA replication GO:0006275 75 48 1,000 0,02181317 0,23890618 ! regulation of endocytosis GO:0030100 63 48 1,000 0,02181317 0,23777393 ! nuclear export GO:0051168 69 48 1,000 0,02181317 0,23665235 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,02267228 0,244818 ! maintenance of location GO:0051235 84 49 1,000 0,02267228 0,24367399 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02351702 0,25157748 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02351702 0,25041277 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02351702 0,24925879 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02351702 0,2481154 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02351702 0,24698245 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02351702 0,24585981 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02351702 0,24474732 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02351702 0,24364485 ! sleep GO:0030431 11 5 0,000 0,02351702 0,24255228 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02351702 0,24146945 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02351702 0,24039626 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02351702 0,23933255 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02351702 0,23827823 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02351702 0,23723315 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02351702 0,23619719 ! tongue development GO:0043586 6 5 0,000 0,02351702 0,23517025 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02351702 0,2341522 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02351702 0,23314292 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02351702 0,23214231 ! cobalt ion transport GO:0006824 9 5 0,000 0,02351702 0,23115025 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02351702 0,23016663 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02351702 0,22919134 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02351702 0,22822429 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02351702 0,22726537 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02351702 0,22631447 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02351702 0,22537149 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02351702 0,22443634 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02351702 0,22350891 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02351702 0,22258913 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02351702 0,22167687 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02351702 0,22077207 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02351702 0,21987462 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02351702 0,21898444 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02351702 0,21810144 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02351702 0,21722553 ! malate metabolic process GO:0006108 7 5 0,000 0,02351702 0,21635663 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02351702 0,21549465 ! behavioral response to pain GO:0048266 7 5 0,000 0,02351702 0,21463951 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02351702 0,21379114 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02351702 0,21294944 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02351702 0,21211434 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02351702 0,21128577 ! mating behavior GO:0007617 6 5 0,000 0,02351702 0,21046365 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02351702 0,2096479 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02351702 0,20883845 ! rhythmic behavior GO:0007622 12 5 0,000 0,02351702 0,20803522 ! copulation GO:0007620 7 5 0,000 0,02351702 0,20723815 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02351702 0,20644717 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02351702 0,2056622 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02351702 0,20488317 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02351702 0,20411003 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02351702 0,2033427 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02351702 0,20258111 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02351702 0,20182521 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02351702 0,20107493 ! response to protozoan GO:0001562 9 5 0,000 0,02351702 0,20033021 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02351702 0,19959099 ! lymph vessel development GO:0001945 7 5 0,000 0,02351702 0,1988572 ! endochondral ossification GO:0001958 12 5 0,000 0,02351702 0,19812878 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02351702 0,19740568 ! parathyroid gland development GO:0060017 8 5 0,000 0,02351702 0,19668785 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02351702 0,19597521 ! anagen GO:0042640 6 5 0,000 0,02351702 0,19526772 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02351702 0,19456531 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02351702 0,19386795 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02351702 0,19317556 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02351702 0,1924881 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02351702 0,19180552 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02351702 0,19112776 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02351702 0,19045478 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02351702 0,18978652 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02351702 0,18912293 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02351702 0,18846396 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02351702 0,18780957 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02351702 0,18715971 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02351702 0,18651434 ! ovulation GO:0030728 6 5 0,000 0,02351702 0,18587339 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02351702 0,18523684 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02351702 0,18460463 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02351702 0,18397673 ! response to pH GO:0009268 9 5 0,000 0,02351702 0,18335308 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02351702 0,18273364 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02351702 0,18211838 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02351702 0,18150724 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02351702 0,18090019 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02351702 0,18029719 ! polyol catabolic process GO:0046174 7 5 0,000 0,02351702 0,1796982 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02351702 0,17910317 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02351702 0,17851207 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02351702 0,17792486 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02351702 0,1773415 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02351702 0,17676195 ! urea metabolic process GO:0019627 6 5 0,000 0,02351702 0,17618618 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02351702 0,17561415 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02351702 0,17504582 ! neutrophil activation GO:0042119 5 5 0,000 0,02351702 0,17448115 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02351702 0,17392012 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02351702 0,17336268 ! response to food GO:0032094 5 5 0,000 0,02351702 0,17280881 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02351702 0,17225846 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02351702 0,17171161 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02351702 0,17116822 ! forebrain neuron development GO:0021884 7 5 0,000 0,02351702 0,17062826 ! melanosome organization GO:0032438 7 5 0,000 0,02351702 0,17009169 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02351702 0,16955849 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02351702 0,16902862 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02351702 0,16850205 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02351702 0,16797875 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02351702 0,16745869 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02351702 0,16694184 ! nucleoside transport GO:0015858 6 5 0,000 0,02351702 0,16642818 ! nucleoside salvage GO:0043174 7 5 0,000 0,02351702 0,16591766 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02351702 0,16541027 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02351702 0,16490597 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02351702 0,16440473 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02351702 0,16390654 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02351702 0,16341135 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02351702 0,16291915 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02351702 0,1624299 ! depyrimidination GO:0045008 8 5 0,000 0,02351702 0,16194358 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02351702 0,16146017 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02351702 0,16097964 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02351702 0,16050195 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02351702 0,16002709 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02351702 0,15955504 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02351702 0,15908576 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02351702 0,15861923 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02351702 0,15815543 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02351702 0,15769434 ! monocyte differentiation GO:0030224 8 5 0,000 0,02351702 0,15723592 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02351702 0,15678017 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02351702 0,15632704 ! centrosome duplication GO:0051298 5 5 0,000 0,02351702 0,15587653 ! response to UV-C GO:0010225 6 5 0,000 0,02351702 0,15542861 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02351702 0,15498326 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02351702 0,15454045 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02351702 0,15410016 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02351702 0,15366238 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02351702 0,15322707 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02351702 0,15279423 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02351702 0,15236382 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02351702 0,15193584 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02351702 0,15151024 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02351702 0,15108703 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02351702 0,15066618 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02351702 0,15024766 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02351702 0,14983146 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02351702 0,14941756 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02351702 0,14900594 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02351702 0,14859659 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02351702 0,14818947 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02351702 0,14778458 ! neural tube patterning GO:0021532 6 5 0,000 0,02351702 0,1473819 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02351702 0,14698141 ! histone demethylation GO:0016577 9 5 0,000 0,02351702 0,14658308 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02351702 0,14618691 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02351702 0,14579288 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02351702 0,14540096 ! enteric nervous system development GO:0048484 8 5 0,000 0,02351702 0,14501115 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02351702 0,14462342 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02351702 0,14423775 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02351702 0,14385414 ! transcription termination GO:0006353 8 5 0,000 0,02351702 0,14347257 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02351702 0,14309301 ! plasminogen activation GO:0031639 5 5 0,000 0,02351702 0,14271545 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02351702 0,14233989 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02351702 0,14196629 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02351702 0,14159465 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02351702 0,14122495 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02351702 0,14085718 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02351702 0,14049132 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02351702 0,14012735 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02351702 0,13976526 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02351702 0,13940504 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02351702 0,13904668 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02351702 0,13869015 ! glial cell migration GO:0008347 10 5 0,000 0,02351702 0,13833544 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02351702 0,13798254 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02351702 0,13763144 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02351702 0,13728213 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02351702 0,13693458 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02351702 0,13658878 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02351702 0,13624473 ! neural plate development GO:0001840 6 5 0,000 0,02351702 0,13590241 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02351702 0,1355618 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02351702 0,13522289 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02351702 0,13488568 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02351702 0,13455014 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02351702 0,13421627 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02351702 0,13388405 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02351702 0,13355348 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02351702 0,13322453 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02351702 0,13289719 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02351702 0,13257146 ! spindle assembly GO:0051225 5 5 0,000 0,02351702 0,13224733 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02351702 0,13192477 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02351702 0,13160379 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02351702 0,13128436 ! organ regeneration GO:0031100 7 5 0,000 0,02351702 0,13096648 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02351702 0,13065014 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02351702 0,13033532 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02351702 0,13002201 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02351702 0,12971021 GO:0055081|anion homeostasis, ! ear development GO:0043583 72 50 1,000 0,0235452 0,12955494 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,0235452 0,12924574 ! lipid modification GO:0030258 73 50 1,000 0,0235452 0,12893801 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,02624545 0,14338369 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,02624545 0,14304392 ! DNA catabolic process GO:0006308 67 54 1,000 0,02717221 0,14774485 ! detection of external stimulus GO:0009581 66 54 1,000 0,02717221 0,1473964 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,02717221 0,14704958 ! nucleoside metabolic process GO:0009116 69 55 1,000 0,02811206 0,15177872 ! tRNA transcription GO:0009304 11 6 0,000 0,02815444 0,15165155 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02815444 0,15129722 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02815444 0,15094455 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02815444 0,15059351 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02815444 0,15024411 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02815444 0,14989632 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02815444 0,14955014 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02815444 0,14920555 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02815444 0,14886255 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02815444 0,14852112 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02815444 0,14818126 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02815444 0,14784294 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02815444 0,14750617 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02815444 0,14717093 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02815444 0,14683721 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02815444 0,146505 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02815444 0,14617429 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02815444 0,14584507 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02815444 0,14551733 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02815444 0,14519105 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02815444 0,14486624 ! neuron adhesion GO:0007158 9 6 0,000 0,02815444 0,14454288 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02815444 0,14422096 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02815444 0,14390047 ! signal peptide processing GO:0006465 8 6 0,000 0,02815444 0,1435814 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02815444 0,14326374 ! mRNA stabilization GO:0048255 15 6 0,000 0,02815444 0,14294748 GO:0043489|RNA stabilization, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02815444 0,14263262 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02815444 0,14231914 ! opsonization GO:0008228 8 6 0,000 0,02815444 0,14200704 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02815444 0,1416963 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02815444 0,14138692 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02815444 0,14107889 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02815444 0,1407722 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02815444 0,14046683 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02815444 0,14016279 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02815444 0,13986006 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02815444 0,13955864 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02815444 0,13925852 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02815444 0,13895968 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02815444 0,13866212 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02815444 0,13836583 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02815444 0,13807081 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02815444 0,13777704 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02815444 0,13748452 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02815444 0,13719324 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02815444 0,13690319 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02815444 0,13661437 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02815444 0,13632676 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02815444 0,13604036 ! thymic T cell selection GO:0045061 12 6 0,000 0,02815444 0,13575516 ! protein lipoylation GO:0009249 10 6 0,000 0,02815444 0,13547115 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02815444 0,13518833 ! pigment granule organization GO:0048753 11 6 0,000 0,02815444 0,13490669 ! drug transport GO:0015893 6 6 0,000 0,02815444 0,13462622 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02815444 0,13434691 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02815444 0,13406876 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02815444 0,13379176 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02815444 0,1335159 ! histidine metabolic process GO:0006547 6 6 0,000 0,02815444 0,13324117 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02815444 0,13296758 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02815444 0,1326951 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02815444 0,13242374 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02815444 0,13215349 ! adenohypophysis development GO:0021984 10 6 0,000 0,02815444 0,13188434 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02815444 0,13161628 ! hyperosmotic response GO:0006972 8 6 0,000 0,02815444 0,13134931 ! microtubule nucleation GO:0007020 10 6 0,000 0,02815444 0,13108342 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02815444 0,13081861 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02815444 0,13055486 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02815444 0,13029217 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02815444 0,13003054 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02815444 0,12976996 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02815444 0,12951042 ! response to dietary excess GO:0002021 7 6 0,000 0,02815444 0,12925192 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02815444 0,12899444 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02815444 0,12873799 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02815444 0,12848256 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02815444 0,12822814 ! purine salvage GO:0043101 8 6 0,000 0,02815444 0,12797472 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02815444 0,12772231 ! neuron apoptosis GO:0051402 8 6 0,000 0,02815444 0,12747089 ! organic alcohol transport GO:0015850 9 6 0,000 0,02815444 0,12722045 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02815444 0,126971 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02815444 0,12672252 ! male sex determination GO:0030238 9 6 0,000 0,02815444 0,12647502 ! carnitine transport GO:0015879 8 6 0,000 0,02815444 0,12622848 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02815444 0,1259829 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02815444 0,12573827 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02815444 0,12549459 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02815444 0,12525186 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02815444 0,12501006 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02815444 0,12476919 ! parturition GO:0007567 12 6 0,000 0,02815444 0,12452925 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02815444 0,12429023 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02815444 0,12405213 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02815444 0,12381493 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02815444 0,12357864 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02815444 0,12334326 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02815444 0,12310876 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02815444 0,12287516 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02815444 0,12264244 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02815444 0,1224106 ! astrocyte development GO:0014002 14 6 0,000 0,02815444 0,12217964 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02815444 0,12194955 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02815444 0,12172032 ! interaction with symbiont GO:0051702 8 6 0,000 0,02815444 0,12149195 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02815444 0,12126444 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02815444 0,12103778 ! eating behavior GO:0042755 6 6 0,000 0,02815444 0,12081196 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02815444 0,12058698 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02815444 0,12036284 ! response to copper ion GO:0046688 9 6 0,000 0,02815444 0,12013954 ! DNA topological change GO:0006265 8 6 0,000 0,02815444 0,11991706 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02815444 0,1196954 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02815444 0,11947456 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02815444 0,11925453 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02815444 0,11903531 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02815444 0,1188169 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02815444 0,11859929 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02815444 0,11838247 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02815444 0,11816644 ! gas homeostasis GO:0033483 11 6 0,000 0,02815444 0,1179512 ! hair follicle maturation GO:0048820 7 6 0,000 0,02815444 0,11773675 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02815444 0,11752307 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02815444 0,11731016 ! Schwann cell development GO:0014044 14 6 0,000 0,02815444 0,11709803 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02815444 0,11688666 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02815444 0,11667605 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02815444 0,1164662 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02815444 0,11625711 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02815444 0,11604876 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02815444 0,11584116 ! histone ubiquitination GO:0016574 7 6 0,000 0,02815444 0,1156343 ! G2 phase GO:0051319 13 6 0,000 0,02815444 0,11542818 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02815444 0,11522279 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02815444 0,11501813 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02815444 0,1148142 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02815444 0,11461099 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02815444 0,1144085 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02815444 0,11420672 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02815444 0,11400565 ! receptor internalization GO:0031623 9 6 0,000 0,02815444 0,11380529 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02815444 0,11360563 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02815444 0,11340667 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02815444 0,11320841 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02815444 0,11301084 ! protein deubiquitination GO:0016579 8 6 0,000 0,02815444 0,11281395 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02815444 0,11261776 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02815444 0,11242224 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02815444 0,1122274 ! axonal fasciculation GO:0007413 9 6 0,000 0,02815444 0,11203324 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02815444 0,11183974 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02815444 0,11164691 ! midbrain development GO:0030901 6 6 0,000 0,02815444 0,11145475 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02815444 0,11126325 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02815444 0,1110724 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02815444 0,11088221 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02815444 0,11069267 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02815444 0,11050377 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02815444 0,11031552 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02815444 0,11012791 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02815444 0,10994093 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02815444 0,10975459 ! adult feeding behavior GO:0008343 6 6 0,000 0,02815444 0,10956888 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02815444 0,1093838 ! blastocyst growth GO:0001832 15 6 0,000 0,02815444 0,10919934 ! pigment granule transport GO:0051904 12 6 0,000 0,02815444 0,1090155 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02815444 0,10883229 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02815444 0,10864968 ! catecholamine transport GO:0051937 7 6 0,000 0,02815444 0,10846769 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02815444 0,1082863 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02815444 0,10810553 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02815444 0,10792535 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02815444 0,10774577 ! protein prenylation GO:0018342 10 6 0,000 0,02815444 0,10756679 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02815444 0,10738841 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02815444 0,10721061 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02815444 0,1070334 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02815444 0,10685678 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02815444 0,10668074 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,03003049 0,11360219 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,03003049 0,11341565 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,03100879 0,11691839 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,03100879 0,11672703 ! lung development GO:0030324 94 59 1,000 0,03199962 0,12026002 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03277009 0,12295467 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03277009 0,12275442 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03277009 0,12255482 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03277009 0,12235587 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03277009 0,12215756 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03277009 0,1219599 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03277009 0,12176287 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03277009 0,12156648 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03277009 0,12137072 ! reproductive behavior GO:0019098 12 7 0,000 0,03277009 0,12117559 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03277009 0,12098108 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03277009 0,1207872 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03277009 0,12059395 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03277009 0,1204013 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03277009 0,12020928 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03277009 0,12001786 ! RNA methylation GO:0001510 11 7 0,000 0,03277009 0,11982705 ! pericardium development GO:0060039 8 7 0,000 0,03277009 0,11963685 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03277009 0,11944725 ! fibril organization GO:0043206 13 7 0,000 0,03277009 0,11925825 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03277009 0,11906985 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03277009 0,11888204 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03277009 0,11869483 ! lipoprotein transport GO:0042953 9 7 0,000 0,03277009 0,1185082 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03277009 0,11832216 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03277009 0,1181367 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03277009 0,11795182 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03277009 0,11776752 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03277009 0,1175838 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03277009 0,11740065 ! chemosensory behavior GO:0007635 9 7 0,000 0,03277009 0,11721806 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,03277009 0,11703605 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03277009 0,1168546 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03277009 0,11667371 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03277009 0,11649338 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03277009 0,1163136 ! reflex GO:0060004 12 7 0,000 0,03277009 0,11613438 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03277009 0,11595572 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03277009 0,1157776 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03277009 0,11560002 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03277009 0,11542299 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03277009 0,11524651 ! spinal cord patterning GO:0021511 7 7 0,000 0,03277009 0,11507056 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03277009 0,11489515 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03277009 0,11472027 ! adrenal gland development GO:0030325 17 7 0,000 0,03277009 0,11454592 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03277009 0,1143721 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03277009 0,11419881 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03277009 0,11402604 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03277009 0,1138538 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03277009 0,11368207 ! endosome organization GO:0007032 10 7 0,000 0,03277009 0,11351087 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03277009 0,11334017 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03277009 0,11316999 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03277009 0,11300032 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03277009 0,11283116 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03277009 0,1126625 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03277009 0,11249435 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03277009 0,1123267 ! galactose metabolic process GO:0006012 10 7 0,000 0,03277009 0,11215955 ! vesicle fusion GO:0006906 15 7 0,000 0,03277009 0,11199289 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03277009 0,11182673 GO:0045851|pH reduction, ! organ growth GO:0035265 11 7 0,000 0,03277009 0,11166106 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03277009 0,11149588 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03277009 0,11133119 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03277009 0,11116698 ! retinol metabolic process GO:0042572 9 7 0,000 0,03277009 0,11100326 ! behavioral fear response GO:0001662 13 7 0,000 0,03277009 0,11084002 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03277009 0,11067726 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03277009 0,11051498 ! rRNA modification GO:0000154 12 7 0,000 0,03277009 0,11035317 ! protein heterooligomerization GO:0051291 10 7 0,000 0,03277009 0,11019184 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03277009 0,11003097 ! response to UV-B GO:0010224 11 7 0,000 0,03277009 0,10987058 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,03277009 0,10971065 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03277009 0,10955119 ! intermediate filament organization GO:0045109 11 7 0,000 0,03277009 0,10939219 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03277009 0,10923365 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03277009 0,10907557 ! fibrinolysis GO:0042730 9 7 0,000 0,03277009 0,10891794 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03277009 0,10876077 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03277009 0,10860406 ! B cell lineage commitment GO:0002326 17 7 0,000 0,03277009 0,10844779 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03277009 0,10829198 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03277009 0,10813661 ! response to tropane GO:0014073 13 7 0,000 0,03277009 0,10798168 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03277009 0,1078272 ! melanosome localization GO:0032400 10 7 0,000 0,03277009 0,10767317 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03277009 0,10751957 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03277009 0,1073664 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03277009 0,10721368 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03277009 0,10706139 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03277009 0,10690953 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03277009 0,1067581 ! mast cell activation GO:0045576 9 7 0,000 0,03277009 0,10660709 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03277009 0,10645652 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03277009 0,10630637 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03277009 0,10615664 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03277009 0,10600734 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03277009 0,10585845 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03277009 0,10570998 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03277009 0,10556193 ! T cell lineage commitment GO:0002360 12 7 0,000 0,03277009 0,10541429 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03277009 0,10526706 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03277009 0,10512025 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03277009 0,10497384 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03277009 0,10482784 ! response to tumor cell GO:0002347 12 7 0,000 0,03277009 0,10468224 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03277009 0,10453705 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03277009 0,10439227 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03277009 0,10424788 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03277009 0,10410389 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03277009 0,1039603 ! diuresis GO:0030146 12 7 0,000 0,03277009 0,1038171 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03277009 0,1036743 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03277009 0,10353189 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03277009 0,10338987 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03277009 0,10324824 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03277009 0,103107 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03277009 0,10296614 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03277009 0,10282567 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03277009 0,10268558 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03277009 0,10254587 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03277009 0,10240654 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03277009 0,10226759 ! lymph node development GO:0048535 9 7 0,000 0,03277009 0,10212902 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03277009 0,10199082 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03277009 0,10185299 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03277009 0,10171554 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03277009 0,10157846 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03277009 0,10144174 ! ATP catabolic process GO:0006200 10 7 0,000 0,03277009 0,1013054 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03277009 0,10116942 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03277009 0,1010338 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03277009 0,10089855 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03277009 0,10076366 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03277009 0,10062913 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03277009 0,10049495 ! muscle adaptation GO:0043500 12 7 0,000 0,03277009 0,10036114 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03277009 0,10022768 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03277009 0,10009458 ! retina homeostasis GO:0001895 9 7 0,000 0,03277009 0,09996182 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03277009 0,09982942 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03277009 0,09969738 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03277009 0,09956567 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03277009 0,09943432 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03277009 0,09930331 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03277009 0,09917265 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03277009 0,09904233 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,03300285 0,09961491 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,03300285 0,09948435 ! urogenital system development GO:0001655 101 61 1,000 0,03401834 0,10241125 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,03401834 0,10227738 ! respiratory tube development GO:0030323 99 62 1,000 0,03504596 0,10522938 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,03608557 0,10820965 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,03608557 0,10806875 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,03713703 0,11107303 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,03713703 0,11092878 ! respiratory system development GO:0060541 100 64 1,000 0,03713703 0,1107849 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03736409 0,11131788 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03736409 0,11117388 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,03736409 0,11103024 ! axon extension GO:0048675 11 8 0,000 0,03736409 0,11088698 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03736409 0,11074408 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03736409 0,11060155 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03736409 0,11045939 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03736409 0,1103176 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03736409 0,11017616 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03736409 0,11003509 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,03736409 0,10989438 ! phosphate transport GO:0006817 10 8 0,000 0,03736409 0,10975403 ! N-glycan processing GO:0006491 12 8 0,000 0,03736409 0,10961404 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03736409 0,1094744 ! UTP metabolic process GO:0046051 8 8 0,000 0,03736409 0,10933512 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03736409 0,1091962 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03736409 0,10905762 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,03736409 0,1089194 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03736409 0,10878153 ! succinate metabolic process GO:0006105 14 8 0,000 0,03736409 0,108644 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03736409 0,10850683 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03736409 0,10837 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03736409 0,10823351 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03736409 0,10809737 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03736409 0,10796157 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03736409 0,10782611 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03736409 0,10769099 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03736409 0,1075562 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03736409 0,10742176 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03736409 0,10728765 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03736409 0,10715387 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03736409 0,10702043 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03736409 0,10688732 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03736409 0,10675454 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03736409 0,10662209 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03736409 0,10648997 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03736409 0,10635818 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03736409 0,10622671 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03736409 0,10609556 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03736409 0,10596474 ! melanin metabolic process GO:0006582 12 8 0,000 0,03736409 0,10583424 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03736409 0,10570407 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03736409 0,10557421 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,03736409 0,10544467 ! macrophage activation GO:0042116 12 8 0,000 0,03736409 0,10531545 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03736409 0,10518654 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03736409 0,10505795 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03736409 0,10492968 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03736409 0,10480172 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03736409 0,10467406 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03736409 0,10454672 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03736409 0,10441969 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03736409 0,10429297 ! ruffle organization GO:0031529 11 8 0,000 0,03736409 0,10416655 ! osteoblast development GO:0002076 13 8 0,000 0,03736409 0,10404044 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03736409 0,10391464 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03736409 0,10378914 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03736409 0,10366394 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03736409 0,10353904 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03736409 0,10341445 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03736409 0,10329015 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03736409 0,10316615 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03736409 0,10304245 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03736409 0,10291905 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03736409 0,10279594 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03736409 0,10267313 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03736409 0,1025506 ! segment specification GO:0007379 10 8 0,000 0,03736409 0,10242838 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03736409 0,10230644 ! cellular extravasation GO:0045123 11 8 0,000 0,03736409 0,10218479 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03736409 0,10206343 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03736409 0,10194236 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03736409 0,10182157 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,03736409 0,10170107 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03736409 0,10158086 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03736409 0,10146093 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03736409 0,10134128 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03736409 0,10122192 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03736409 0,10110283 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03736409 0,10098403 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03736409 0,1008655 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03736409 0,10074725 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03736409 0,10062928 ! icosanoid secretion GO:0032309 12 8 0,000 0,03736409 0,10051159 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03736409 0,10039417 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03736409 0,10027702 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03736409 0,10016015 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03736409 0,10004355 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03736409 0,09992722 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03736409 0,09981116 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03736409 0,09969537 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03736409 0,09957985 ! sterol catabolic process GO:0016127 9 8 0,000 0,03736409 0,09946459 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03736409 0,0993496 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03736409 0,09923488 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03736409 0,09912042 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03736409 0,09900623 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03736409 0,0988923 ! prophase GO:0051324 11 8 0,000 0,03736409 0,09877863 ! S phase GO:0051320 8 8 0,000 0,03736409 0,09866522 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03736409 0,09855207 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03736409 0,09843918 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03736409 0,09832655 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03736409 0,09821418 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03736409 0,09810206 ! hormone catabolic process GO:0042447 13 8 0,000 0,03736409 0,0979902 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03736409 0,0978786 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03736409 0,09776724 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03736409 0,09765614 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03736409 0,0975453 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03736409 0,0974347 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03736409 0,09732436 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03736409 0,09721426 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03736409 0,09710441 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03736409 0,09699482 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03736409 0,09688546 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03736409 0,09677636 ! regulation of embryonic development GO:0045995 16 8 0,000 0,03736409 0,0966675 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03736409 0,09655888 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03736409 0,09645051 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,03736409 0,09634238 ! reproductive structure development GO:0048608 90 65 1,000 0,03820021 0,098388 ! regulation of caspase activity GO:0043281 97 65 1,000 0,03820021 0,09827795 ! antigen processing and presentation GO:0019882 96 66 1,000 0,03927498 0,10093013 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,03927498 0,10081748 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,04036122 0,1034903 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,04036122 0,10337506 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,04145878 0,10606807 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,04145878 0,10595022 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04193653 0,10705218 ! regulation of developmental growth GO:0048638 13 9 0,000 0,04193653 0,1069335 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,04193653 0,10681508 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04193653 0,10669692 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04193653 0,10657902 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04193653 0,10646138 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04193653 0,10634401 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04193653 0,10622689 GO:0010469|regulation of receptor activity, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04193653 0,10611003 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04193653 0,10599342 ! GTP metabolic process GO:0046039 9 9 0,000 0,04193653 0,10587707 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04193653 0,10576098 ! social behavior GO:0035176 14 9 0,000 0,04193653 0,10564514 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04193653 0,10552956 ! artery development GO:0060840 19 9 0,000 0,04193653 0,10541422 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04193653 0,10529914 ! regulation of glycolysis GO:0006110 15 9 0,000 0,04193653 0,10518431 ! response to pain GO:0048265 16 9 0,000 0,04193653 0,10506973 ! protein complex disassembly GO:0043241 17 9 0,000 0,04193653 0,1049554 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04193653 0,10484132 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04193653 0,10472749 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04193653 0,1046139 ! lung alveolus development GO:0048286 17 9 0,000 0,04193653 0,10450056 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04193653 0,10438746 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,04193653 0,10427461 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04193653 0,104162 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04193653 0,10404964 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04193653 0,10393752 ! protein targeting to ER GO:0045047 19 9 0,000 0,04193653 0,10382563 ! T cell selection GO:0045058 18 9 0,000 0,04193653 0,10371399 ! endoderm development GO:0007492 12 9 0,000 0,04193653 0,10360259 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04193653 0,10349143 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04193653 0,10338051 ! arginine catabolic process GO:0006527 10 9 0,000 0,04193653 0,10326982 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04193653 0,10315937 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04193653 0,10304916 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04193653 0,10293918 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04193653 0,10282944 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,04193653 0,10271993 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04193653 0,10261065 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04193653 0,10250161 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04193653 0,1023928 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04193653 0,10228421 ! mannose metabolic process GO:0006013 9 9 0,000 0,04193653 0,10217586 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04193653 0,10206774 ! receptor clustering GO:0043113 15 9 0,000 0,04193653 0,10195985 ! epithelial cell development GO:0002064 10 9 0,000 0,04193653 0,10185218 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04193653 0,10174474 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04193653 0,10163753 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04193653 0,10153054 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04193653 0,10142378 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04193653 0,10131724 ! motor axon guidance GO:0008045 14 9 0,000 0,04193653 0,10121093 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04193653 0,10110484 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04193653 0,10099897 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04193653 0,10089332 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04193653 0,10078789 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04193653 0,10068269 ! DNA ligation GO:0006266 14 9 0,000 0,04193653 0,1005777 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04193653 0,10047293 ! response to amine stimulus GO:0014075 13 9 0,000 0,04193653 0,10036838 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04193653 0,10026405 ! erythrocyte development GO:0048821 11 9 0,000 0,04193653 0,10015993 ! renal water homeostasis GO:0003091 14 9 0,000 0,04193653 0,10005603 ! postreplication repair GO:0006301 11 9 0,000 0,04193653 0,09995235 ! mRNA cleavage GO:0006379 13 9 0,000 0,04193653 0,09984888 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04193653 0,09974562 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04193653 0,09964258 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04193653 0,09953975 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04193653 0,09943713 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04193653 0,09933472 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04193653 0,09923252 ! acid secretion GO:0046717 14 9 0,000 0,04193653 0,09913054 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04193653 0,09902876 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04193653 0,09892719 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04193653 0,09882583 ! purine base metabolic process GO:0006144 18 9 0,000 0,04193653 0,09872468 ! oocyte differentiation GO:0009994 12 9 0,000 0,04193653 0,09862374 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,04193653 0,098523 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04193653 0,09842246 ! spleen development GO:0048536 15 9 0,000 0,04193653 0,09832213 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,04193653 0,09822201 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04193653 0,09812209 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04193653 0,09802237 ! detection of calcium ion GO:0005513 13 9 0,000 0,04193653 0,09792286 ! blastocyst formation GO:0001825 12 9 0,000 0,04193653 0,09782354 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04193653 0,09772443 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04193653 0,09762552 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04193653 0,09752681 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04193653 0,0974283 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04193653 0,09732998 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04193653 0,09723187 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04193653 0,09713395 ! prepulse inhibition GO:0060134 14 9 0,000 0,04193653 0,09703623 ! embryonic placenta development GO:0001892 12 9 0,000 0,04193653 0,09693871 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04193653 0,09684138 ! insulin secretion GO:0030073 17 9 0,000 0,04193653 0,09674425 ! response to nicotine GO:0035094 16 9 0,000 0,04193653 0,09664731 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04193653 0,09655056 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04193653 0,09645401 ! localization within membrane GO:0051668 15 9 0,000 0,04193653 0,09635766 ! response to metal ion GO:0010038 103 70 1,000 0,04368738 0,10028041 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,04368738 0,10018043 ! steroid biosynthetic process GO:0006694 94 71 1,000 0,04481816 0,10267108 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,04595976 0,10518153 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,04595976 0,10507697 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,04595976 0,10497263 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,04595976 0,10486849 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,04595976 0,10476456 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,04648751 0,10586264 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,04648751 0,10575793 ! neuron fate specification GO:0048665 11 10 0,000 0,04648751 0,10565343 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,04648751 0,10554913 ! thyroid gland development GO:0030878 19 10 0,000 0,04648751 0,10544504 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,04648751 0,10534115 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,04648751 0,10523747 ! synapsis GO:0007129 13 10 0,000 0,04648751 0,10513399 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,04648751 0,10503071 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,04648751 0,10492764 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,04648751 0,10482477 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,04648751 0,1047221 ! sulfate transport GO:0008272 12 10 0,000 0,04648751 0,10461964 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,04648751 0,10451737 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,04648751 0,1044153 ! phospholipid efflux GO:0033700 16 10 0,000 0,04648751 0,10431343 ! hippocampus development GO:0021766 19 10 0,000 0,04648751 0,10421176 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,04648751 0,10411029 ! blood vessel remodeling GO:0001974 21 10 0,000 0,04648751 0,10400901 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,04648751 0,10390794 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,04648751 0,10380706 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,04648751 0,10370637 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,04648751 0,10360588 ! pathogenesis GO:0009405 13 10 0,000 0,04648751 0,10350558 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,04648751 0,10340548 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04648751 0,10330557 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,04648751 0,10320586 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,04648751 0,10310633 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,04648751 0,103007 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,04648751 0,10290786 ! melanocyte differentiation GO:0030318 15 10 0,000 0,04648751 0,10280891 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,04648751 0,10271015 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,04648751 0,10261158 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04648751 0,1025132 ! response to X-ray GO:0010165 16 10 0,000 0,04648751 0,10241501 ! B cell proliferation GO:0042100 14 10 0,000 0,04648751 0,102317 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,04648751 0,10221918 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,04648751 0,10212155 ! forebrain cell migration GO:0021885 17 10 0,000 0,04648751 0,10202411 ! lipid digestion GO:0044241 15 10 0,000 0,04648751 0,10192685 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,04648751 0,10182978 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,04648751 0,10173289 ! UV protection GO:0009650 14 10 0,000 0,04648751 0,10163619 ! entry into host cell GO:0030260 20 10 0,000 0,04648751 0,10153967 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,04648751 0,10144333 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,04648751 0,10134717 ! negative regulation of ossification GO:0030279 19 10 0,000 0,04648751 0,1012512 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,04648751 0,10115541 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,04648751 0,1010598 ! regulation of bone resorption GO:0045124 24 10 0,000 0,04648751 0,10096437 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,04648751 0,10086912 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,04648751 0,10077405 ! regulation of organ growth GO:0046620 11 10 0,000 0,04648751 0,10067916 ! response to dsRNA GO:0043331 18 10 0,000 0,04648751 0,10058445 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,04648751 0,10048991 ! embryonic axis specification GO:0000578 12 10 0,000 0,04648751 0,10039556 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,04648751 0,10030138 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,04648751 0,10020737 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,04648751 0,10011355 ! cranial nerve development GO:0021545 12 10 0,000 0,04648751 0,10001989 ! fucose catabolic process GO:0019317 16 10 0,000 0,04648751 0,09992642 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,04648751 0,09983312 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,04648751 0,09973999 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04648751 0,09964703 ! zymogen activation GO:0031638 14 10 0,000 0,04648751 0,09955425 ! salivary gland development GO:0007431 22 10 0,000 0,04648751 0,09946164 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04648751 0,09936921 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,04648751 0,09927694 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,04648751 0,09918485 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,04648751 0,09909293 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,04648751 0,09900117 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,04648751 0,09890959 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04648751 0,09881818 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,04648751 0,09872693 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,04648751 0,09863586 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,04648751 0,09854495 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,04648751 0,09845421 ! detection of bacterium GO:0016045 10 10 0,000 0,04648751 0,09836363 ! embryonic gut development GO:0048566 11 10 0,000 0,04648751 0,09827322 ! activation of innate immune response GO:0002218 10 10 0,000 0,04648751 0,09818298 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,04648751 0,09809291 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,04648751 0,09800299 ! developmental induction GO:0031128 13 10 0,000 0,04648751 0,09791325 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,04648751 0,09782367 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,04648751 0,09773425 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,04648751 0,09764499 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,04648751 0,0975559 ! mitochondrion organization GO:0007005 104 73 1,000 0,04711205 0,09877639 ! cellular lipid catabolic process GO:0044242 105 73 1,000 0,04711205 0,09868643 ! response to oxygen levels GO:0070482 137 74 1,000 0,0482749 0,10103028 ! protein import into nucleus GO:0006606 118 74 1,000 0,0482749 0,10093844 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,0482749 0,10084676 ! response to inorganic substance GO:0010035 115 75 1,000 0,04944821 0,10320406 ! nuclear import GO:0051170 121 75 1,000 0,04944821 0,1031105 ! tRNA metabolic process GO:0006399 95 76 1,000 0,05063183 0,10548298 ! response to unfolded protein GO:0006986 99 76 1,000 0,05063183 0,10538752 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,05063183 0,10529224 ! regulation of protein transport GO:0051223 114 76 1,000 0,05063183 0,10519712 GO:0070201|regulation of establishment of protein localization, ! rRNA transcription GO:0009303 17 11 0,000 0,05101713 0,10590198 ! respiratory burst GO:0045730 14 11 0,000 0,05101713 0,10580649 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05101713 0,10571117 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05101713 0,10561602 ! virus-host interaction GO:0019048 17 11 0,000 0,05101713 0,10552104 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,05101713 0,10542623 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,05101713 0,10533159 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05101713 0,10523713 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05101713 0,10514283 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,05101713 0,1050487 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,05101713 0,10495474 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05101713 0,10486094 ! T cell proliferation GO:0042098 20 11 0,000 0,05101713 0,10476732 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05101713 0,10467386 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,05101713 0,10458057 ! bone resorption GO:0045453 16 11 0,000 0,05101713 0,10448744 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05101713 0,10439448 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05101713 0,10430168 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05101713 0,10420905 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,05101713 0,10411659 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05101713 0,10402429 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05101713 0,10393215 ! syncytium formation GO:0006949 15 11 0,000 0,05101713 0,10384017 ! plasma membrane organization GO:0007009 18 11 0,000 0,05101713 0,10374836 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05101713 0,10365671 ! focal adhesion formation GO:0048041 24 11 0,000 0,05101713 0,10356522 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05101713 0,10347389 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05101713 0,10338273 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,05101713 0,10329172 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05101713 0,10320088 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05101713 0,10311019 ! adult heart development GO:0007512 11 11 0,000 0,05101713 0,10301966 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05101713 0,10292929 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,05101713 0,10283908 ! temperature homeostasis GO:0001659 16 11 0,000 0,05101713 0,10274903 ! L-glutamate transport GO:0015813 16 11 0,000 0,05101713 0,10265914 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05101713 0,1025694 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05101713 0,10247982 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05101713 0,1023904 ! stem cell development GO:0048864 29 11 0,000 0,05101713 0,10230113 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05101713 0,10221202 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05101713 0,10212306 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05101713 0,10203426 ! vasoconstriction GO:0042310 15 11 0,000 0,05101713 0,10194561 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05101713 0,10185711 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05101713 0,10176877 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05101713 0,10168059 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05101713 0,10159255 ! ribosome assembly GO:0042255 13 11 0,000 0,05101713 0,10150467 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05101713 0,10141694 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05101713 0,10132936 ! chromatin silencing GO:0006342 19 11 0,000 0,05101713 0,10124193 ! nucleosome positioning GO:0016584 13 11 0,000 0,05101713 0,10115465 ! T cell homeostasis GO:0043029 20 11 0,000 0,05101713 0,10106752 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05101713 0,10098055 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,05101713 0,10089372 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05101713 0,10080704 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05101713 0,10072051 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05101713 0,10063413 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05101713 0,1005479 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05101713 0,10046181 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05101713 0,10037587 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05101713 0,10029008 ! male genitalia development GO:0030539 13 11 0,000 0,05101713 0,10020444 ! cholesterol efflux GO:0033344 19 11 0,000 0,05101713 0,10011894 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05101713 0,10003359 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05101713 0,09994838 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05101713 0,09986332 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05101713 0,0997784 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05101713 0,09969362 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05101713 0,09960899 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,05101713 0,09952451 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,05101713 0,09944017 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05101713 0,09935597 ! lysogeny GO:0030069 18 11 0,000 0,05101713 0,09927191 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05101713 0,09918799 ! acrosome reaction GO:0007340 13 11 0,000 0,05101713 0,09910422 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05101713 0,09902059 ! regulation of DNA binding GO:0051101 119 77 1,000 0,05182566 0,10050507 ! gland development GO:0048732 148 77 1,000 0,05182566 0,1004204 ! sex differentiation GO:0007548 105 77 1,000 0,05182566 0,10033587 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,05182566 0,10025148 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,05182566 0,10016724 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,05302956 0,10240805 ! chromatin assembly GO:0031497 102 80 1,000 0,05546713 0,1070255 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 1,000 0,05546713 0,10693579 ! regulation of GTPase activity GO:0043087 129 80 1,000 0,05546713 0,10684623 ! lactation GO:0007595 20 12 0,000 0,05552549 0,10686914 ! reproductive cellular process GO:0048610 14 12 0,000 0,05552549 0,10677979 ! tRNA modification GO:0006400 14 12 0,000 0,05552549 0,10669058 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05552549 0,10660152 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05552549 0,10651262 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,05552549 0,10642386 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05552549 0,10633524 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05552549 0,10624678 ! non-recombinational repair GO:0000726 19 12 0,000 0,05552549 0,10615846 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05552549 0,10607029 ! peroxisomal transport GO:0043574 21 12 0,000 0,05552549 0,10598226 ! cartilage condensation GO:0001502 18 12 0,000 0,05552549 0,10589438 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,05552549 0,10580665 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05552549 0,10571906 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,05552549 0,10563162 ! heart looping GO:0001947 15 12 0,000 0,05552549 0,10554432 ! palate development GO:0060021 15 12 0,000 0,05552549 0,10545716 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,05552549 0,10537015 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05552549 0,10528329 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05552549 0,10519656 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05552549 0,10510998 ! arginine metabolic process GO:0006525 13 12 0,000 0,05552549 0,10502354 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05552549 0,10493724 ! methionine metabolic process GO:0006555 13 12 0,000 0,05552549 0,10485109 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05552549 0,10476507 ! Golgi organization GO:0007030 18 12 0,000 0,05552549 0,1046792 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05552549 0,10459347 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05552549 0,10450788 ! monoamine transport GO:0015844 13 12 0,000 0,05552549 0,10442243 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05552549 0,10433711 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,05552549 0,10425194 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05552549 0,10416691 ! L-amino acid transport GO:0015807 20 12 0,000 0,05552549 0,10408201 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05552549 0,10399725 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05552549 0,10391263 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05552549 0,10382815 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05552549 0,10374381 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05552549 0,1036596 ! cerebellum development GO:0021549 13 12 0,000 0,05552549 0,10357553 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05552549 0,10349159 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,05552549 0,10340779 ! histone methylation GO:0016571 15 12 0,000 0,05552549 0,10332413 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05552549 0,1032406 ! gland morphogenesis GO:0022612 23 12 0,000 0,05552549 0,10315721 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05552549 0,10307395 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05552549 0,10299083 ! response to gamma radiation GO:0010332 20 12 0,000 0,05552549 0,10290784 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05552549 0,10282498 ! intestinal absorption GO:0050892 19 12 0,000 0,05552549 0,10274226 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05552549 0,10265967 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05552549 0,10257721 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,05552549 0,10249488 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05552549 0,10241269 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,05552549 0,10233063 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05552549 0,1022487 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05552549 0,1021669 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05552549 0,10208523 ! response to cold GO:0009409 14 12 0,000 0,05552549 0,1020037 ! mRNA transport GO:0051028 121 81 1,000 0,05670056 0,10407923 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,05670056 0,10399623 ! response to protein stimulus GO:0051789 111 81 1,000 0,05670056 0,10391337 ! regulation of neurological system process GO:0031644 122 81 1,000 0,05670056 0,10383063 ! detection of stimulus GO:0051606 108 82 1,000 0,05794359 0,10602247 ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,0591961 0,10822817 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,0591961 0,10814221 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06001269 0,10954697 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06001269 0,1094601 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06001269 0,10937336 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06001269 0,10928677 ! water transport GO:0006833 17 13 0,000 0,06001269 0,10920031 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06001269 0,10911398 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06001269 0,10902779 ! lipid localization GO:0010876 24 13 0,000 0,06001269 0,10894174 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06001269 0,10885583 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06001269 0,10877004 ! organelle fusion GO:0048284 28 13 0,000 0,06001269 0,1086844 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06001269 0,10859889 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06001269 0,10851351 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,06001269 0,10842827 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06001269 0,10834316 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06001269 0,10825819 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06001269 0,10817334 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06001269 0,10808863 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06001269 0,10800406 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06001269 0,10791961 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06001269 0,1078353 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06001269 0,10775112 ! NAD metabolic process GO:0019674 21 13 0,000 0,06001269 0,10766707 ! exocrine system development GO:0035272 27 13 0,000 0,06001269 0,10758315 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06001269 0,10749937 ! bone mineralization GO:0030282 15 13 0,000 0,06001269 0,10741571 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06001269 0,10733218 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06001269 0,10724878 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06001269 0,10716552 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06001269 0,10708238 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06001269 0,10699937 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06001269 0,10691649 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,06001269 0,10683374 ! genitalia development GO:0048806 15 13 0,000 0,06001269 0,10675111 ! regulation of cellular pH GO:0030641 20 13 0,000 0,06001269 0,10666861 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,06001269 0,10658624 ! tissue regeneration GO:0042246 21 13 0,000 0,06001269 0,106504 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06001269 0,10642189 ! cofactor transport GO:0051181 19 13 0,000 0,06001269 0,1063399 ! NADP metabolic process GO:0006739 18 13 0,000 0,06001269 0,10625803 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06001269 0,1061763 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06001269 0,10609469 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06001269 0,1060132 ! gas transport GO:0015669 18 13 0,000 0,06001269 0,10593184 ! regulation of RNA stability GO:0043487 28 13 0,000 0,06001269 0,1058506 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06001269 0,10576949 ! regulation of axon extension GO:0030516 23 13 0,000 0,06001269 0,1056885 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06001269 0,10560764 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06001269 0,1055269 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06001269 0,10544628 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06001269 0,10536579 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06001269 0,10528542 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06001269 0,10520517 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,06045799 0,10590509 ! protein-DNA complex assembly GO:0065004 107 84 1,000 0,06045799 0,1058245 ! sterol metabolic process GO:0016125 120 84 1,000 0,06045799 0,10574402 ! transcription initiation GO:0006352 118 85 1,000 0,06172914 0,10788528 ! regulation of protein localization GO:0032880 132 85 1,000 0,06172914 0,10780336 ! nucleosome organization GO:0034728 114 87 1,000 0,06429876 0,11220573 ! cellular defense response GO:0006968 102 87 1,000 0,06429876 0,11212066 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,06429876 0,11203572 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,06429876 0,11195091 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,06447883 0,1121795 ! superoxide anion generation GO:0042554 18 14 0,000 0,06447883 0,11209471 ! neuron maturation GO:0042551 21 14 0,000 0,06447883 0,11201005 ! regulation of S phase GO:0033261 18 14 0,000 0,06447883 0,11192551 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,06447883 0,1118411 ! myotube differentiation GO:0014902 21 14 0,000 0,06447883 0,11175682 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,06447883 0,11167267 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,06447883 0,11158864 ! inositol metabolic process GO:0006020 20 14 0,000 0,06447883 0,11150474 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,06447883 0,11142096 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,06447883 0,11133731 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,06447883 0,11125379 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,06447883 0,11117039 ! gene silencing by RNA GO:0031047 20 14 0,000 0,06447883 0,11108712 ! response to cAMP GO:0051591 19 14 0,000 0,06447883 0,11100397 ! limbic system development GO:0021761 25 14 0,000 0,06447883 0,11092094 ! startle response GO:0001964 21 14 0,000 0,06447883 0,11083804 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,06447883 0,11075527 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,06447883 0,11067261 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,06447883 0,11059008 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,06447883 0,11050768 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,06447883 0,11042539 ! glycine metabolic process GO:0006544 22 14 0,000 0,06447883 0,11034323 ! pituitary gland development GO:0021983 23 14 0,000 0,06447883 0,11026119 ! cellular response to starvation GO:0009267 21 14 0,000 0,06447883 0,11017927 ! lysosomal transport GO:0007041 20 14 0,000 0,06447883 0,11009748 ! regulation of heart rate GO:0002027 23 14 0,000 0,06447883 0,1100158 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,06447883 0,10993425 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,06447883 0,10985282 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,06447883 0,1097715 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,06447883 0,10969031 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,06447883 0,10960924 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,06447883 0,10952829 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,06447883 0,10944745 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,06447883 0,10936674 ! axon cargo transport GO:0008088 27 14 0,000 0,06447883 0,10928615 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,06447883 0,10920567 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,06447883 0,10912531 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,06447883 0,10904507 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,06447883 0,10896495 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06447883 0,10888495 ! mRNA splice site selection GO:0006376 26 14 0,000 0,06447883 0,10880506 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,06447883 0,10872529 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,06447883 0,10864564 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,06447883 0,10856611 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,06447883 0,10848669 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,06447883 0,10840738 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,06447883 0,1083282 ! muscle maintenance GO:0046716 19 14 0,000 0,06447883 0,10824913 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,06447883 0,10817017 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,06447883 0,10809133 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,06447883 0,1080126 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,06447883 0,10793399 ! cell killing GO:0001906 20 14 0,000 0,06447883 0,10785549 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,06447883 0,10777711 ! cilium assembly GO:0042384 20 14 0,000 0,06447883 0,10769884 ! peptide hormone secretion GO:0030072 23 14 0,000 0,06447883 0,10762068 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 1,000 0,065597 0,10940762 ! establishment of RNA localization GO:0051236 128 88 1,000 0,065597 0,10932834 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,065597 0,10924917 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,06690405 0,11134538 ! reproductive developmental process GO:0003006 127 89 1,000 0,06690405 0,11126487 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 1,000 0,06690405 0,11118448 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,068924 0,11445863 ! positive regulation of cell size GO:0045793 20 15 0,000 0,068924 0,11437604 ! metencephalon development GO:0022037 19 15 0,000 0,068924 0,11429358 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,068924 0,11421124 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,068924 0,11412901 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,068924 0,1140469 ! skin development GO:0043588 25 15 0,000 0,068924 0,11396491 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,068924 0,11388304 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,068924 0,11380129 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,068924 0,11371965 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,068924 0,11363813 ! bile acid metabolic process GO:0008206 22 15 0,000 0,068924 0,11355673 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,068924 0,11347544 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,068924 0,11339427 ! adult walking behavior GO:0007628 25 15 0,000 0,068924 0,11331322 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,068924 0,11323228 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,068924 0,11315146 ! myoblast differentiation GO:0045445 27 15 0,000 0,068924 0,11307075 ! centrosome cycle GO:0007098 16 15 0,000 0,068924 0,11299016 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,068924 0,11290968 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,068924 0,11282932 ! cerebral cortex development GO:0021987 29 15 0,000 0,068924 0,11274907 ! response to osmotic stress GO:0006970 22 15 0,000 0,068924 0,11266894 ! vesicle coating GO:0006901 25 15 0,000 0,068924 0,11258892 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,068924 0,11250901 ! DNA integration GO:0015074 22 15 0,000 0,068924 0,11242922 ! peptide secretion GO:0002790 27 15 0,000 0,068924 0,11234954 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,068924 0,11226997 ! regulation of vasodilation GO:0042312 24 15 0,000 0,068924 0,11219051 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,068924 0,11211117 ! neuron recognition GO:0008038 22 15 0,000 0,068924 0,11203194 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,068924 0,11195282 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,068924 0,11187382 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,068924 0,11179492 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,068924 0,11171614 ! biomineral formation GO:0031214 18 15 0,000 0,068924 0,11163746 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,068924 0,1115589 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,068924 0,11148045 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,068924 0,11140211 ! organic cation transport GO:0015695 19 15 0,000 0,068924 0,11132387 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,068924 0,11124575 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,068924 0,11116774 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,068924 0,11108984 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,068924 0,11101204 ! defense response to virus GO:0051607 27 15 0,000 0,068924 0,11093436 ! peptide hormone processing GO:0016486 19 15 0,000 0,068924 0,11085678 ! RNA localization GO:0006403 135 91 1,000 0,06954413 0,11177603 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,07087694 0,11383866 ! sulfur metabolic process GO:0006790 118 92 1,000 0,07087694 0,11375922 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,07221812 0,11583102 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,07221812 0,1157503 ! protein secretion GO:0009306 27 16 0,000 0,0733483 0,11747987 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,0733483 0,11739812 ! hormone secretion GO:0046879 25 16 0,000 0,0733483 0,11731648 ! bone remodeling GO:0046849 24 16 0,000 0,0733483 0,11723495 ! endothelial cell migration GO:0043542 22 16 0,000 0,0733483 0,11715354 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,0733483 0,11707224 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,0733483 0,11699105 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,0733483 0,11690997 ! glial cell development GO:0021782 24 16 0,000 0,0733483 0,11682901 ! patterning of blood vessels GO:0001569 24 16 0,000 0,0733483 0,11674816 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,0733483 0,11666742 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,0733483 0,1165868 ! protein polyubiquitination GO:0000209 26 16 0,000 0,0733483 0,11650628 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,0733483 0,11642588 ! fructose metabolic process GO:0006000 20 16 0,000 0,0733483 0,11634558 ! regulation of protein binding GO:0043393 27 16 0,000 0,0733483 0,1162654 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,0733483 0,11618533 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,0733483 0,11610536 ! negative regulation of immune response GO:0050777 28 16 0,000 0,0733483 0,11602551 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,0733483 0,11594577 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,0733483 0,11586614 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,0733483 0,11578661 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,0733483 0,1157072 ! diencephalon development GO:0021536 25 16 0,000 0,0733483 0,11562789 ! oogenesis GO:0048477 23 16 0,000 0,0733483 0,11554869 ! neural crest cell migration GO:0001755 24 16 0,000 0,0733483 0,11546961 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,0733483 0,11539063 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,0733483 0,11531175 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,0733483 0,11523299 ! steroid catabolic process GO:0006706 22 16 0,000 0,0733483 0,11515433 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,0733483 0,11507578 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,0733483 0,11499734 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,0733483 0,114919 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,0733483 0,11484077 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,0733483 0,11476265 ! sperm-egg recognition GO:0035036 16 16 0,000 0,0733483 0,11468463 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,0733483 0,11460672 ! nerve development GO:0021675 18 16 0,000 0,0733483 0,11452892 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,0733483 0,11445122 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,0733483 0,11437362 ! response to oxidative stress GO:0006979 141 94 1,000 0,07356756 0,1146378 ! regulation of binding GO:0051098 151 95 1,000 0,07492516 0,11667426 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,07629081 0,11872048 ! response to light stimulus GO:0009416 153 96 1,000 0,07629081 0,11864021 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,07775183 0,12083055 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,07775183 0,12074897 ! negative regulation of defense response GO:0031348 19 17 0,000 0,07775183 0,12066749 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,07775183 0,12058612 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,07775183 0,12050486 ! glycerol metabolic process GO:0006071 20 17 0,000 0,07775183 0,12042372 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,07775183 0,12034268 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,07775183 0,12026175 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,07775183 0,12018093 ! signal complex assembly GO:0007172 29 17 0,000 0,07775183 0,12010021 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,07775183 0,12001961 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,07775183 0,11993911 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,07775183 0,11985872 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,07775183 0,11977844 ! memory GO:0007613 25 17 0,000 0,07775183 0,11969827 ! keratinization GO:0031424 17 17 0,000 0,07775183 0,11961821 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,07775183 0,11953825 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,07775183 0,1194584 ! retinoid metabolic process GO:0001523 22 17 0,000 0,07775183 0,11937865 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,07775183 0,11929901 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,07775183 0,11921948 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,07775183 0,11914005 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,07775183 0,11906073 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,07775183 0,11898152 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,07775183 0,11890241 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,07775183 0,1188234 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,07775183 0,1187445 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,07775183 0,11866571 ! membrane budding GO:0006900 29 17 0,000 0,07775183 0,11858701 ! heme metabolic process GO:0042168 27 17 0,000 0,07775183 0,11850843 ! actin filament bundle formation GO:0051017 26 17 0,000 0,07775183 0,11842995 ! neuromuscular junction development GO:0007528 23 17 0,000 0,07775183 0,11835157 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,07775183 0,11827329 ! body fluid secretion GO:0007589 27 17 0,000 0,07775183 0,11819512 ! stem cell differentiation GO:0048863 36 17 0,000 0,07775183 0,11811705 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,07775183 0,11803909 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,07775183 0,11796123 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,07775183 0,11788347 ! sensory perception of pain GO:0019233 23 17 0,000 0,07775183 0,11780581 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,07775183 0,11772825 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,07775183 0,1176508 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,07775183 0,11757345 ! synaptogenesis GO:0007416 24 17 0,000 0,07775183 0,1174962 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,07775183 0,11741905 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,07775183 0,11734201 ! cell-cell junction organization GO:0045216 25 17 0,000 0,07775183 0,11726506 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,07775183 0,11718822 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,07775183 0,11711147 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,07775183 0,11703483 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,07775183 0,11695828 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,07775183 0,11688184 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,07775183 0,1168055 ! protein import GO:0017038 156 99 1,000 0,08043503 0,12075755 ! regulation of translation GO:0006417 151 100 1,000 0,08183184 0,12277445 ! protein localization in organelle GO:0033365 161 100 1,000 0,08183184 0,12269441 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,08213469 0,12306827 ! positive regulation of translation GO:0045727 28 18 0,000 0,08213469 0,12298814 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,08213469 0,12290813 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,08213469 0,12282821 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,08213469 0,1227484 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,08213469 0,12266869 ! cAMP metabolic process GO:0046058 33 18 0,000 0,08213469 0,12258909 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,08213469 0,12250959 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,08213469 0,12243019 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,08213469 0,1223509 ! axis specification GO:0009798 26 18 0,000 0,08213469 0,12227171 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,08213469 0,12219262 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,08213469 0,12211363 ! pancreas development GO:0031016 26 18 0,000 0,08213469 0,12203475 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,08213469 0,12195596 ! response to retinoic acid GO:0032526 25 18 0,000 0,08213469 0,12187728 ! pigmentation during development GO:0048066 31 18 0,000 0,08213469 0,1217987 ! central nervous system neuron development GO:0021954 30 18 0,000 0,08213469 0,12172022 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,08213469 0,12164185 ! fucose metabolic process GO:0006004 26 18 0,000 0,08213469 0,12156357 ! response to fungus GO:0009620 19 18 0,000 0,08213469 0,12148539 ! peptide cross-linking GO:0018149 31 18 0,000 0,08213469 0,12140732 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,08213469 0,12132934 ! heart process GO:0003015 27 18 0,000 0,08213469 0,12125147 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,08213469 0,12117369 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,08213469 0,12109602 ! visual learning GO:0008542 35 18 0,000 0,08213469 0,12101844 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,08213469 0,12094097 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,08213469 0,12086359 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,08213469 0,12078631 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,08213469 0,12070913 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,08213469 0,12063205 ! vitamin transport GO:0051180 24 18 0,000 0,08213469 0,12055507 ! hormone transport GO:0009914 27 18 0,000 0,08213469 0,12047818 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,08213469 0,12040139 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,08213469 0,12032471 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,08213469 0,12024812 ! cell-cell recognition GO:0009988 20 18 0,000 0,08213469 0,12017162 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,08213469 0,12009522 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,08213469 0,12001893 ! regulation of glucose import GO:0046324 21 18 0,000 0,08213469 0,11994272 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,08213469 0,11986662 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,08213469 0,11979061 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,08213469 0,1197147 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,08213469 0,11963888 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,08649697 0,12591331 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,08649697 0,12583367 ! positive regulation of ossification GO:0045778 30 19 0,000 0,08649697 0,12575413 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,08649697 0,12567469 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,08649697 0,12559535 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,08649697 0,12551611 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,08649697 0,12543697 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,08649697 0,12535793 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,08649697 0,12527898 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,08649697 0,12520014 ! regeneration GO:0031099 32 19 0,000 0,08649697 0,1251214 ! sensory perception of taste GO:0050909 23 19 0,000 0,08649697 0,12504276 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,08649697 0,12496421 ! smooth muscle contraction GO:0006939 36 19 0,000 0,08649697 0,12488577 ! peroxisome organization GO:0007031 29 19 0,000 0,08649697 0,12480742 ! digestive system process GO:0022600 30 19 0,000 0,08649697 0,12472917 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,08649697 0,12465102 ! response to vitamin A GO:0033189 26 19 0,000 0,08649697 0,12457297 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,08649697 0,12449501 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,08649697 0,12441715 ! response to starvation GO:0042594 30 19 0,000 0,08649697 0,12433939 ! sex determination GO:0007530 29 19 0,000 0,08649697 0,12426173 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,08649697 0,12418416 ! plasma membrane fusion GO:0045026 23 19 0,000 0,08649697 0,12410669 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,08649697 0,12402932 ! cytolysis GO:0019835 20 19 0,000 0,08649697 0,12395204 ! renal system process GO:0003014 35 19 0,000 0,08649697 0,12387486 ! vasodilation GO:0042311 33 19 0,000 0,08649697 0,12379778 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,08649697 0,12372079 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,08649697 0,1236439 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,08649697 0,1235671 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,08649697 0,1234904 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,08649697 0,12341379 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,08649697 0,12333728 ! sarcomere organization GO:0045214 23 19 0,000 0,08649697 0,12326086 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,08649697 0,12318454 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,08649697 0,12310831 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,08649697 0,12303218 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,08649697 0,12295614 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,08649697 0,12288019 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,09083876 0,12896861 ! iron ion transport GO:0006826 37 20 0,000 0,09083876 0,12888905 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,09083876 0,12880959 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,09083876 0,12873022 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,09083876 0,12865096 ! response to vitamin GO:0033273 29 20 0,000 0,09083876 0,12857179 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,09083876 0,12849271 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,09083876 0,12841374 ! spinal cord development GO:0021510 31 20 0,000 0,09083876 0,12833486 ! response to ethanol GO:0045471 37 20 0,000 0,09083876 0,12825608 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,09083876 0,1281774 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,09083876 0,12809881 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,09083876 0,12802032 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,09083876 0,12794192 ! chromosome condensation GO:0030261 31 20 0,000 0,09083876 0,12786362 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,09083876 0,12778542 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,09083876 0,12770731 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,09083876 0,12762929 ! pallium development GO:0021543 38 20 0,000 0,09083876 0,12755138 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,09083876 0,12747355 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,09083876 0,12739583 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,09083876 0,12731819 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,09083876 0,12724065 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,09083876 0,12716321 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,09083876 0,12708586 ! collagen catabolic process GO:0030574 25 20 0,000 0,09083876 0,1270086 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,09083876 0,12693144 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,09083876 0,12685437 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,09083876 0,1267774 ! alditol metabolic process GO:0019400 24 20 0,000 0,09083876 0,12670052 ! actin filament-based movement GO:0030048 34 20 0,000 0,09083876 0,12662373 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,09516017 0,13256716 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,09516017 0,13248692 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,09516017 0,13240677 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,09516017 0,13232672 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,09516017 0,13224676 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,09516017 0,1321669 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,09516017 0,13208714 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,09516017 0,13200747 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,09516017 0,1319279 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,09516017 0,13184843 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,09516017 0,13176905 ! vesicle docking GO:0048278 27 21 0,000 0,09516017 0,13168976 ! phototransduction GO:0007602 25 21 0,000 0,09516017 0,13161058 ! visual behavior GO:0007632 39 21 0,000 0,09516017 0,13153148 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,09516017 0,13145248 ! ovarian follicle development GO:0001541 30 21 0,000 0,09516017 0,13137358 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,09516017 0,13129477 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,09516017 0,13121606 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,09516017 0,13113744 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,09516017 0,13105891 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,09516017 0,13098048 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,09516017 0,13090215 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,09516017 0,1308239 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,09516017 0,13074575 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,09516017 0,13066769 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,09516017 0,13058973 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,09516017 0,13051186 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,09516017 0,13043408 ! fatty acid transport GO:0015908 30 21 0,000 0,09516017 0,13035639 ! immunoglobulin production GO:0002377 33 21 0,000 0,09516017 0,1302788 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,09516017 0,1302013 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,09516017 0,13012389 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,09516017 0,13004658 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,09516017 0,12996935 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,09516017 0,12989222 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,09516017 0,12981518 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,09516017 0,12973823 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,09516017 0,12966137 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,09516017 0,1295846 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,09516017 0,12950792 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,09516017 0,12943133 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,09516017 0,12935484 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,09516017 0,12927843 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,09516017 0,12920212 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,09946128 0,13496221 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,09946128 0,13488263 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,09946128 0,13480315 ! viral genome replication GO:0019079 29 22 0,000 0,09946128 0,13472376 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,09946128 0,13464446 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,09946128 0,13456526 ! leukocyte adhesion GO:0007159 38 22 0,000 0,09946128 0,13448615 ! molting cycle process GO:0022404 40 22 0,000 0,09946128 0,13440713 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,09946128 0,13432821 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,09946128 0,13424938 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,09946128 0,13417064 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,09946128 0,13409199 ! vasculogenesis GO:0001570 33 22 0,000 0,09946128 0,13401344 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,09946128 0,13393498 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,09946128 0,13385661 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,09946128 0,13377833 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,09946128 0,13370014 ! lysosome organization GO:0007040 37 22 0,000 0,09946128 0,13362205 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,09946128 0,13354404 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,09946128 0,13346613 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,09946128 0,13338831 ! regulation of behavior GO:0050795 38 22 0,000 0,09946128 0,13331057 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,09946128 0,13323293 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,09946128 0,13315538 ! membrane depolarization GO:0051899 35 22 0,000 0,09946128 0,13307792 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,09946128 0,13300055 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,09946128 0,13292327 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,09946128 0,13284608 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,09946128 0,13276897 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,09946128 0,13269196 ! blastocyst development GO:0001824 37 22 0,000 0,09946128 0,13261504 ! neural tube closure GO:0001843 33 22 0,000 0,09946128 0,13253821 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,09946128 0,13246146 ! protein tetramerization GO:0051262 39 22 0,000 0,09946128 0,13238481 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,10374219 0,13800291 ! neuron fate commitment GO:0048663 32 23 0,000 0,10374219 0,13792314 ! embryonic pattern specification GO:0009880 31 23 0,000 0,10374219 0,13784347 ! myelination GO:0042552 35 23 0,000 0,10374219 0,13776388 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,10374219 0,13768439 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,10374219 0,13760498 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,10374219 0,13752567 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,10374219 0,13744645 ! vesicle targeting GO:0006903 32 23 0,000 0,10374219 0,13736732 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,10374219 0,13728829 ! osteoblast differentiation GO:0001649 40 23 0,000 0,10374219 0,13720934 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,10374219 0,13713048 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,10374219 0,13705172 ! interaction with host GO:0051701 37 23 0,000 0,10374219 0,13697304 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,10374219 0,13689446 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,10374219 0,13681596 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,10374219 0,13673756 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,10374219 0,13665924 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,10374219 0,13658102 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,10374219 0,13650288 ! cell fate determination GO:0001709 45 23 0,000 0,10374219 0,13642484 ! pentose metabolic process GO:0019321 31 23 0,000 0,10374219 0,13634688 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,10374219 0,13626901 ! spermatid development GO:0007286 33 23 0,000 0,10374219 0,13619123 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,10374219 0,13611354 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,10374219 0,13603594 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,10374219 0,13595843 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,10374219 0,135881 ! telomere organization GO:0032200 32 23 0,000 0,10374219 0,13580367 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,10374219 0,13572642 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,10374219 0,13564926 ! regulation of amine transport GO:0051952 38 23 0,000 0,10374219 0,13557218 ! liver development GO:0001889 40 23 0,000 0,10374219 0,1354952 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,108003 0,14098007 ! initiation of viral infection GO:0019059 42 24 0,000 0,108003 0,14090011 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,108003 0,14082023 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,108003 0,14074045 ! superoxide metabolic process GO:0006801 32 24 0,000 0,108003 0,14066075 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,108003 0,14058115 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,108003 0,14050164 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,108003 0,14042221 ! sperm motility GO:0030317 27 24 0,000 0,108003 0,14034288 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,108003 0,14026363 ! vacuole organization GO:0007033 39 24 0,000 0,108003 0,14018448 ! receptor metabolic process GO:0043112 37 24 0,000 0,108003 0,14010541 ! neural crest cell development GO:0014032 39 24 0,000 0,108003 0,14002643 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,108003 0,13994754 ! primary neural tube formation GO:0014020 35 24 0,000 0,108003 0,13986875 ! negative regulation of cell development GO:0010721 56 24 0,000 0,108003 0,13979003 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,108003 0,13971141 ! base-excision repair GO:0006284 31 24 0,000 0,108003 0,13963288 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,108003 0,13955443 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,108003 0,13947608 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,108003 0,13939781 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,108003 0,13931963 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,108003 0,13924153 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,11224379 0,14462785 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,11224379 0,14454687 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,11224379 0,14446598 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,11224379 0,14438519 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,11224379 0,14430448 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,11224379 0,14422386 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,11224379 0,14414334 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,11224379 0,1440629 ! male gonad development GO:0008584 33 25 0,000 0,11224379 0,14398255 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,11224379 0,14390229 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,11224379 0,14382212 ! phospholipid transport GO:0015914 35 25 0,000 0,11224379 0,14374205 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,11224379 0,14366206 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,11224379 0,14358215 ! detection of light stimulus GO:0009583 30 25 0,000 0,11224379 0,14350234 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,11224379 0,14342262 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,11224379 0,14334298 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,11224379 0,14326344 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,11646466 0,14856834 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,11646466 0,14848599 ! translational initiation GO:0006413 43 26 0,000 0,11646466 0,14840372 ! regulation of pH GO:0006885 36 26 0,000 0,11646466 0,14832155 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,11646466 0,14823947 ! circadian rhythm GO:0007623 42 26 0,000 0,11646466 0,14815748 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,11646466 0,14807558 ! post-embryonic development GO:0009791 42 26 0,000 0,11646466 0,14799377 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,11646466 0,14791205 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,11646466 0,14783042 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,11646466 0,14774888 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,11646466 0,14766743 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,11646466 0,14758607 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,11646466 0,1475048 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,11646466 0,14742362 ! regulation of coagulation GO:0050818 39 26 0,000 0,11646466 0,14734253 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,12066571 0,15257346 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,12066571 0,15248963 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,12066571 0,15240589 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,12066571 0,15232224 ! membrane docking GO:0022406 39 27 0,000 0,12066571 0,15223868 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,12066571 0,15215522 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,12066571 0,15207185 ! acute-phase response GO:0006953 42 27 0,000 0,12066571 0,15198857 ! myofibril assembly GO:0030239 36 27 0,000 0,12066571 0,15190538 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,12066571 0,15182228 ! response to ionizing radiation GO:0010212 47 27 0,000 0,12066571 0,15173927 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,12066571 0,15165635 ! natural killer cell activation GO:0030101 35 27 0,000 0,12066571 0,15157352 ! lipid oxidation GO:0034440 38 27 0,000 0,12066571 0,15149079 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,12066571 0,15140814 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,12066571 0,15132558 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,12066571 0,15124312 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,12066571 0,15116074 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,12066571 0,15107846 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,12066571 0,15099626 ! gene silencing GO:0016458 41 27 0,000 0,12066571 0,15091415 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,12484701 0,15605877 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,12484701 0,155974 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,12484701 0,15588932 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,12484701 0,15580474 ! cell junction assembly GO:0034329 56 28 0,000 0,12484701 0,15572025 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,12484701 0,15563584 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,12484701 0,15555153 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,12484701 0,15546732 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,12484701 0,15538319 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,12484701 0,15529915 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,12484701 0,15521521 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,12484701 0,15513135 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,12484701 0,15504759 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,12484701 0,15496391 ! mesoderm formation GO:0001707 46 28 0,000 0,12484701 0,15488033 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,12484701 0,15479684 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,12484701 0,15471343 ! ensheathment of neurons GO:0007272 43 28 0,000 0,12484701 0,15463012 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,12484701 0,1545469 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,12484701 0,15446376 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,12484701 0,15438072 ! neural tube formation GO:0001841 41 28 0,000 0,12484701 0,15429776 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,12484701 0,15421489 ! placenta development GO:0001890 37 28 0,000 0,12484701 0,15413212 ! regulation of B cell activation GO:0050864 42 28 0,000 0,12484701 0,15404943 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,12900868 0,15909918 ! regulation of innate immune response GO:0045088 38 29 0,000 0,12900868 0,15901391 ! ovulation cycle process GO:0022602 41 29 0,000 0,12900868 0,15892874 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,12900868 0,15884366 ! protein targeting to membrane GO:0006612 53 29 0,000 0,12900868 0,15875867 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,12900868 0,15867378 ! mismatch repair GO:0006298 34 29 0,000 0,12900868 0,15858897 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,12900868 0,15850425 ! muscle cell development GO:0055001 38 29 0,000 0,12900868 0,15841963 ! formation of primary germ layer GO:0001704 48 29 0,000 0,12900868 0,15833509 ! telencephalon development GO:0021537 52 29 0,000 0,12900868 0,15825065 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,12900868 0,15816629 ! eye morphogenesis GO:0048592 51 29 0,000 0,12900868 0,15808203 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,12900868 0,15799785 ! tissue homeostasis GO:0001894 42 29 0,000 0,12900868 0,15791376 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,13315079 0,16289724 ! collagen metabolic process GO:0032963 40 30 0,000 0,13315079 0,16281064 ! organic anion transport GO:0015711 51 30 0,000 0,13315079 0,16272413 ! cholesterol transport GO:0030301 46 30 0,000 0,13315079 0,16263772 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,13315079 0,16255139 ! spliceosome assembly GO:0000245 49 30 0,000 0,13315079 0,16246516 ! spindle organization GO:0007051 37 30 0,000 0,13315079 0,16237901 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,13315079 0,16229296 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,13315079 0,162207 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,13315079 0,16212113 ! ceramide metabolic process GO:0006672 43 30 0,000 0,13315079 0,16203535 ! ovulation cycle GO:0042698 43 30 0,000 0,13315079 0,16194967 ! hindbrain development GO:0030902 45 30 0,000 0,13315079 0,16186407 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,13315079 0,16177856 ! adult locomotory behavior GO:0008344 47 30 0,000 0,13315079 0,16169315 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,13315079 0,16160782 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,13315079 0,16152258 ! response to heat GO:0009408 41 30 0,000 0,13315079 0,16143744 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,13315079 0,16135238 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,13315079 0,16126741 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,13727344 0,16617311 ! negative regulation of secretion GO:0051048 49 31 0,000 0,13727344 0,1660857 ! mammary gland development GO:0030879 57 31 0,000 0,13727344 0,16599838 ! glial cell differentiation GO:0010001 55 31 0,000 0,13727344 0,16591115 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,13727344 0,16582401 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,13727344 0,16573696 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,13727344 0,16565001 ! odontogenesis GO:0042476 50 31 0,000 0,13727344 0,16556314 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,13727344 0,16547637 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,13727344 0,16538969 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,13727344 0,1653031 ! metanephros development GO:0001656 58 31 0,000 0,13727344 0,1652166 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,13727344 0,16513018 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,13727344 0,16504386 ! cell fate specification GO:0001708 37 31 0,000 0,13727344 0,16495764 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,13727344 0,1648715 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,13727344 0,16478545 ! RNA modification GO:0009451 40 31 0,000 0,13727344 0,16469949 ! regulation of muscle development GO:0048634 48 32 0,000 0,14137672 0,16953413 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,14137672 0,16944578 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,14137672 0,16935753 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,14137672 0,16926937 ! meiosis I GO:0007127 52 32 0,000 0,14137672 0,1691813 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,14137672 0,16909332 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,14137672 0,16900543 ! peripheral nervous system development GO:0007422 53 32 0,000 0,14137672 0,16891764 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,14137672 0,16882993 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,14137672 0,16874232 ! cytokine production GO:0001816 44 32 0,000 0,14137672 0,1686548 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,14137672 0,16856737 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,14137672 0,16848003 ! vesicle localization GO:0051648 47 32 0,000 0,14137672 0,16839278 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,14546071 0,17316752 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,14546071 0,17307793 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,14546071 0,17298844 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,14546071 0,17289904 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,14546071 0,17280973 ! sister chromatid segregation GO:0000819 46 33 0,000 0,14546071 0,17272052 ! actomyosin structure organization GO:0031032 43 33 0,000 0,14546071 0,1726314 ! cell junction organization GO:0034330 63 33 0,000 0,14546071 0,17254236 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,14546071 0,17245342 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,14546071 0,17236458 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,14546071 0,17227582 ! female gonad development GO:0008585 49 33 0,000 0,14546071 0,17218716 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,14546071 0,17209858 ! positive regulation of cell development GO:0010720 54 33 0,000 0,14546071 0,1720101 ! lipid homeostasis GO:0055088 55 33 0,000 0,14546071 0,17192171 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,14546071 0,17183341 ! regulation of proteolysis GO:0030162 50 33 0,000 0,14546071 0,1717452 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,14546071 0,17165708 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,14546071 0,17156905 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,14546071 0,17148111 ! cytokinesis GO:0000910 52 33 0,000 0,14546071 0,17139326 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,14952552 0,17609252 ! mRNA catabolic process GO:0006402 48 34 0,000 0,14952552 0,1760024 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,14952552 0,17591237 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,14952552 0,17582244 ! feeding behavior GO:0007631 45 34 0,000 0,14952552 0,1757326 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,14952552 0,17564285 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,14952552 0,17555319 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,14952552 0,17546362 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,14952552 0,17537414 ! neuron migration GO:0001764 46 34 0,000 0,14952552 0,17528476 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,14952552 0,17519546 ! female gamete generation GO:0007292 43 34 0,000 0,14952552 0,17510626 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,14952552 0,17501715 ! polyol metabolic process GO:0019751 44 34 0,000 0,14952552 0,17492812 ! aerobic respiration GO:0009060 47 34 0,000 0,14952552 0,17483919 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,14952552 0,17475035 ! embryonic organ development GO:0048568 45 34 0,000 0,14952552 0,1746616 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,14952552 0,17457294 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,15357122 0,17920538 ! Notch signaling pathway GO:0007219 56 35 0,000 0,15357122 0,17911451 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,15357122 0,17902372 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,15357122 0,17893303 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,15357122 0,17884243 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,15357122 0,17875193 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,15357122 0,17866151 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,15357122 0,17857118 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,15357122 0,17848095 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,15357122 0,17839081 ! pigment metabolic process GO:0042440 61 35 0,000 0,15357122 0,17830076 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,15357122 0,1782108 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,15357122 0,17812093 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,1575979 0,18269918 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,1575979 0,18260714 ! negative regulation of binding GO:0051100 58 36 0,000 0,1575979 0,1825152 ! tissue remodeling GO:0048771 62 36 0,000 0,1575979 0,18242334 ! neural tube development GO:0021915 50 36 0,000 0,1575979 0,18233158 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,1575979 0,18223991 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,1575979 0,18214833 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,1575979 0,18205685 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,1575979 0,18196545 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,16160566 0,18649926 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,16160566 0,18640573 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,16160566 0,1863123 ! learning GO:0007612 67 37 0,000 0,16160566 0,18621895 ! ion transmembrane transport GO:0034220 56 37 0,000 0,16160566 0,1861257 ! regulation of protein secretion GO:0050708 51 37 0,000 0,16160566 0,18603255 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,16160566 0,18593948 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,16559459 0,19043377 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,16559459 0,1903386 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,16559459 0,19024353 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,16559459 0,19014855 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,16559459 0,19005367 ! phagocytosis GO:0006909 60 38 0,000 0,16559459 0,18995888 ! mesenchymal cell development GO:0014031 64 38 0,000 0,16559459 0,18986418 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,16559459 0,18976958 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,16956476 0,19422258 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,16956476 0,1941259 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,16956476 0,19402932 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,16956476 0,19393284 ! male sex differentiation GO:0046661 53 39 0,000 0,16956476 0,19383645 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,16956476 0,19374016 ! chromatin remodeling GO:0006338 68 39 0,000 0,16956476 0,19364396 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,16956476 0,19354786 ! JNK cascade GO:0007254 54 39 0,000 0,16956476 0,19345185 ! developmental growth GO:0048589 62 39 0,000 0,16956476 0,19335594 ! synapse organization GO:0050808 55 39 0,000 0,16956476 0,19326013 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,17351626 0,19766588 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,17351626 0,19756802 ! regulation of tube size GO:0035150 60 40 0,000 0,17351626 0,19747026 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,17351626 0,1973726 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,17351626 0,19727504 ! inner ear development GO:0048839 57 40 0,000 0,17351626 0,19717757 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,17351626 0,1970802 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,17351626 0,19698292 ! double-strand break repair GO:0006302 67 40 0,000 0,17351626 0,19688574 ! B cell differentiation GO:0030183 62 40 0,000 0,17351626 0,19678866 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,17351626 0,19669167 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,17351626 0,19659478 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,17744919 0,20095182 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,17744919 0,20085292 ! glucose transport GO:0015758 52 41 0,000 0,17744919 0,20075413 ! endosome transport GO:0016197 71 41 0,000 0,17744919 0,20065543 ! striated muscle contraction GO:0006941 62 41 0,000 0,17744919 0,20055683 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,17744919 0,20045832 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,17744919 0,20035991 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,17744919 0,2002616 ! mitochondrial transport GO:0006839 60 42 0,000 0,18136363 0,20457889 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,18136363 0,2044786 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,18136363 0,20437842 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,18136363 0,20427833 ! hexose transport GO:0008645 54 42 0,000 0,18136363 0,20417834 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,18136363 0,20407845 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,18136363 0,20397865 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,18136363 0,20387896 ! excretion GO:0007588 63 42 0,000 0,18136363 0,20377936 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,18136363 0,20367986 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,18136363 0,20358045 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,18525966 0,2078523 ! leukocyte migration GO:0050900 60 43 0,000 0,18525966 0,20775096 ! neuromuscular process GO:0050905 79 43 0,000 0,18525966 0,20764972 ! tRNA processing GO:0008033 49 43 0,000 0,18525966 0,20754858 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,18525966 0,20744753 ! vesicle organization GO:0016050 79 43 0,000 0,18525966 0,20734658 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,18525966 0,20724573 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,18913738 0,21148078 ! glycolysis GO:0006096 53 44 0,000 0,18913738 0,21137802 ! regulation of action potential GO:0001508 71 44 0,000 0,18913738 0,21127536 ! regulation of ion transport GO:0043269 57 44 0,000 0,18913738 0,2111728 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,18913738 0,21107034 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,18913738 0,21096798 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,18913738 0,21086571 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,18913738 0,21076355 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,18913738 0,21066148 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,18913738 0,21055952 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,18913738 0,21045765 ! RNA catabolic process GO:0006401 64 45 0,000 0,19299686 0,21464834 ! positive regulation of defense response GO:0031349 59 45 0,000 0,19299686 0,2145446 ! regulation of translational initiation GO:0006446 64 45 0,000 0,19299686 0,21444095 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,19299686 0,21433741 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,19299686 0,21423396 ! cell recognition GO:0008037 58 45 0,000 0,19299686 0,21413062 ! cell maturation GO:0048469 60 45 0,000 0,19299686 0,21402737 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,19683819 0,21818208 ! cell redox homeostasis GO:0045454 63 46 0,000 0,19683819 0,21807699 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,19683819 0,21797199 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,19683819 0,2178671 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,20066145 0,22199198 ! viral infectious cycle GO:0019058 71 47 0,000 0,20066145 0,22188526 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,20066145 0,22177863 ! endocrine system development GO:0035270 83 47 0,000 0,20066145 0,22167211 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,20066145 0,22156569 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,20066145 0,22145937 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,20066145 0,22135316 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,20066145 0,22124704 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,20066145 0,22114103 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,20066145 0,22103512 ! chloride transport GO:0006821 67 48 0,000 0,20446673 0,22511895 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,20446673 0,22501124 ! response to temperature stimulus GO:0009266 62 48 0,000 0,20446673 0,22490363 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,20446673 0,22479612 ! gastrulation GO:0007369 73 48 0,000 0,20446673 0,22468872 ! heart morphogenesis GO:0003007 65 48 0,000 0,20446673 0,22458141 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,20446673 0,22447422 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,20446673 0,22436712 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,20446673 0,22426013 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,20446673 0,22415323 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,20446673 0,22404644 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,20825412 0,22808784 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,20825412 0,22797928 ! sensory perception of smell GO:0007608 61 49 0,000 0,20825412 0,22787082 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,20825412 0,22776247 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,20825412 0,22765421 ! RNA elongation GO:0006354 62 49 0,000 0,20825412 0,22754607 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,20825412 0,22743802 ! germ cell development GO:0007281 68 49 0,000 0,20825412 0,22733007 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,20825412 0,22722223 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,20825412 0,22711449 ! cartilage development GO:0051216 70 49 0,000 0,20825412 0,22700686 ! regulation of actin filament length GO:0030832 72 50 0,000 0,21202369 0,23100638 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,21202369 0,23089701 ! membrane fusion GO:0006944 80 50 0,000 0,21202369 0,23078773 ! positive regulation of growth GO:0045927 67 50 0,000 0,21202369 0,23067856 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,21202369 0,23056949 ! proton transport GO:0015992 75 50 0,000 0,21202369 0,23046053 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,21202369 0,23035167 ! positive regulation of secretion GO:0051047 71 51 0,000 0,21577552 0,23431714 ! hydrogen transport GO:0006818 77 51 0,000 0,21577552 0,23420656 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,21577552 0,23409609 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,21577552 0,23398572 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,21577552 0,23387545 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,21577552 0,23376529 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,21577552 0,23365523 ! adult behavior GO:0030534 80 51 0,000 0,21577552 0,23354527 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,21577552 0,23343542 ! transition metal ion transport GO:0000041 74 52 0,000 0,21950971 0,23736358 ! regulation of cellular component size GO:0032535 74 52 0,000 0,21950971 0,23725204 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,21950971 0,2371406 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,21950971 0,23702927 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,21950971 0,23691804 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,22322633 0,2408164 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,22322633 0,2407035 ! kidney development GO:0001822 90 53 0,000 0,22322633 0,2405907 ! single fertilization GO:0007338 59 53 0,000 0,22322633 0,24047802 ! amino acid transport GO:0006865 84 54 0,000 0,22692547 0,24434858 ! regulation of mitosis GO:0007088 84 54 0,000 0,22692547 0,24423424 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,22692547 0,24412001 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,22692547 0,24400588 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,22692547 0,24389186 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,22692547 0,24377794 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,22692547 0,24366413 ! exocytosis GO:0006887 74 55 0,000 0,2306072 0,24750189 ! mesoderm development GO:0007498 76 55 0,000 0,2306072 0,24738645 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,2306072 0,24727112 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,2342716 0,25108326 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,2342716 0,25096632 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,2342716 0,25084948 ! carbohydrate transport GO:0008643 74 57 0,000 0,23791876 0,25463618 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,23791876 0,25451775 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,23791876 0,25439942 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,23791876 0,25428121 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,23791876 0,2541631 ! camera-type eye development GO:0043010 88 57 0,000 0,23791876 0,25404511 ! secondary metabolic process GO:0019748 84 57 0,000 0,23791876 0,25392722 ! developmental maturation GO:0021700 75 57 0,000 0,23791876 0,25380944 ! gonad development GO:0008406 79 57 0,000 0,23791876 0,25369178 ! viral reproductive process GO:0022415 87 58 0,000 0,24154876 0,25744308 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,24154876 0,25732383 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,24154876 0,2572047 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,24516168 0,26093099 ! activation of MAPK activity GO:0000187 84 59 0,000 0,24516168 0,2608103 ! actin filament organization GO:0007015 95 59 0,000 0,24516168 0,26068972 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,24516168 0,26056925 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,24875759 0,26426904 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,24875759 0,26414703 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,24875759 0,26402513 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,24875759 0,26390335 ! regulation of heart contraction GO:0008016 91 60 0,000 0,24875759 0,26378168 ! fertilization GO:0009566 68 60 0,000 0,24875759 0,26366012 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,25233658 0,26733032 ! meiosis GO:0007126 96 61 0,000 0,25233658 0,26720724 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,25233658 0,26708428 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,25233658 0,26696142 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,25233658 0,26683868 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,25233658 0,26671605 ! extracellular matrix organization GO:0030198 103 61 0,000 0,25233658 0,26659354 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,25233658 0,26647114 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,25233658 0,26634885 ! amine catabolic process GO:0009310 90 62 0,000 0,25589872 0,26998489 ! neurotransmitter transport GO:0006836 81 62 0,000 0,25589872 0,2698611 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,25589872 0,26973742 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,25589872 0,26961386 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,25589872 0,26949041 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,25589872 0,26936708 ! meiotic cell cycle GO:0051321 97 62 0,000 0,25589872 0,26924385 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,2594441 0,2728493 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,2594441 0,2727246 ! viral reproduction GO:0016032 92 63 0,000 0,2594441 0,27260001 ! regulation of lipase activity GO:0060191 109 63 0,000 0,2594441 0,27247553 ! negative regulation of cell size GO:0045792 108 64 0,000 0,26297278 0,2760554 ! appendage morphogenesis GO:0035107 93 64 0,000 0,26297278 0,27592947 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,26297278 0,27580364 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,26297278 0,27567794 ! hexose catabolic process GO:0019320 82 64 0,000 0,26297278 0,27555234 ! adaptive immune response GO:0002250 94 64 0,000 0,26297278 0,27542686 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 0,000 0,26648485 0,27897822 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,26648485 0,2788513 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,26648485 0,27872449 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,26648485 0,2785978 ! defense response to bacterium GO:0042742 73 65 0,000 0,26648485 0,27847122 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,26648485 0,27834476 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,26648485 0,27821841 ! activation of immune response GO:0002253 83 65 0,000 0,26648485 0,27809218 ! protein oligomerization GO:0051259 100 65 0,000 0,26648485 0,27796606 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,26998039 0,28148454 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,26998039 0,281357 ! axon guidance GO:0007411 99 66 0,000 0,26998039 0,28122957 ! regulation of immune effector process GO:0002697 101 66 0,000 0,26998039 0,28110226 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,27345946 0,28459582 ! acute inflammatory response GO:0002526 92 68 0,000 0,27692216 0,28806919 ! learning or memory GO:0007611 123 68 0,000 0,27692216 0,28793896 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,27692216 0,28780884 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,27692216 0,28767885 ! rhythmic process GO:0048511 105 68 0,000 0,27692216 0,28754897 ! inorganic anion transport GO:0015698 93 68 0,000 0,27692216 0,28741921 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,28036855 0,29086499 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,28036855 0,29073385 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,28036855 0,29060283 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,28379872 0,2940257 ! humoral immune response GO:0006959 86 70 0,000 0,28379872 0,29389331 ! eye development GO:0001654 111 70 0,000 0,28379872 0,29376105 ! amine transport GO:0015837 101 70 0,000 0,28379872 0,2936289 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,28379872 0,29349687 ! regulation of catabolic process GO:0009894 106 70 0,000 0,28379872 0,29336496 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,28721272 0,29676068 ! muscle cell differentiation GO:0042692 104 71 0,000 0,28721272 0,29662742 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,28721272 0,29649428 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,28721272 0,29636127 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,28721272 0,29622837 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,28721272 0,29609559 ! negative regulation of transport GO:0051051 116 73 0,000 0,29399258 0,30294934 ! regulation of blood pressure GO:0008217 107 73 0,000 0,29399258 0,30281367 ! tube morphogenesis GO:0035239 118 73 0,000 0,29399258 0,30267812 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,29399258 0,3025427 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,29735857 0,30586973 ! digestion GO:0007586 97 74 0,000 0,29735857 0,305733 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,29735857 0,30559639 ! blood coagulation GO:0007596 116 75 0,000 0,30070871 0,30890131 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,30070871 0,30876341 ! response to nutrient GO:0007584 104 75 0,000 0,30070871 0,30862563 ! regulation of ligase activity GO:0051340 114 75 0,000 0,30070871 0,30848797 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,30070871 0,30835044 ! amine biosynthetic process GO:0009309 97 76 0,000 0,30404307 0,3116306 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,30736172 0,31489174 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,30736172 0,31475154 ! protein ubiquitination GO:0016567 125 77 0,000 0,30736172 0,31461146 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,30736172 0,31447151 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,31066474 0,3177096 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,31066474 0,3175684 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,31395219 0,32078633 ! cellular respiration GO:0045333 107 79 0,000 0,31395219 0,32064389 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,31395219 0,32050157 ! T cell activation GO:0042110 134 79 0,000 0,31395219 0,32035938 ! regulation of lyase activity GO:0051339 133 79 0,000 0,31395219 0,32021731 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,31395219 0,32007537 ! alcohol catabolic process GO:0046164 104 80 0,000 0,31722415 0,32326786 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,31722415 0,32312469 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 131 80 0,000 0,31722415 0,32298165 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,3204807 0,32615292 ! hemostasis GO:0007599 125 81 0,000 0,3204807 0,32600867 ! vitamin metabolic process GO:0006766 103 81 0,000 0,3204807 0,32586455 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,3204807 0,32572055 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,3237219 0,32886942 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,32694782 0,33199999 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of defense response GO:0031347 117 84 0,000 0,33015854 0,33511238 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,33335413 0,33820666 ! rRNA metabolic process GO:0016072 107 85 0,000 0,33335413 0,33805754 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,33335413 0,33790855 ! regulation of membrane potential GO:0042391 128 85 0,000 0,33335413 0,33775969 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,33335413 0,33761096 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,33653465 0,34068209 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,33970019 0,34373534 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! female pregnancy GO:0007565 130 87 0,000 0,33970019 0,34358418 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,3428508 0,34661839 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,3428508 0,3464661 GO:0016054|organic acid catabolic process, ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,34598656 0,34948137 ! regulation of T cell activation GO:0050863 128 89 0,000 0,34598656 0,34932796 ! hormone metabolic process GO:0042445 121 90 0,000 0,34910753 0,35232441 ! ATP metabolic process GO:0046034 137 91 0,000 0,35221379 0,35530339 ! response to virus GO:0009615 122 91 0,000 0,35221379 0,35514762 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,35530541 0,35810799 ! cell fate commitment GO:0045165 141 92 0,000 0,35530541 0,35795113 ! positive regulation of immune response GO:0050778 121 92 0,000 0,35530541 0,35779441 ! DNA recombination GO:0006310 146 92 0,000 0,35530541 0,35763783 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,35838244 0,36057726 ! electron transport chain GO:0022900 123 94 0,000 0,36144497 0,36349953 ! angiogenesis GO:0001525 149 95 0,000 0,36449305 0,36640473 ! carboxylic acid transport GO:0046942 147 95 0,000 0,36449305 0,36624466 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,36752676 0,36913168 ! in utero embryonic development GO:0001701 147 96 0,000 0,36752676 0,36897056 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,37054616 0,37183951 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,3765423 0,3776918 ! extracellular structure organization GO:0043062 156 99 0,000 0,3765423 0,37752715 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,37951917 0,38034601 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,37951917 0,38018036 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,37951917 0,38001484 ! divalent metal ion transport GO:0070838 171 100 0,000 0,37951917 0,37984948 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,37951917 0,37968425 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,37951917 0,37951917